3.4.22.B32: calpain 12

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For detailed information about calpain 12, go to the full flat file.

Reaction

broad endopeptidase specificity =

Synonyms

Capn12

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.22 Cysteine endopeptidases

                3.4.22.B32 calpain 12

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1	AA Sequence
1	Application
1	CAS Registry Number
3	Disease/ Diagnostics
3	General Information
1	Metals/Ions
7	Organism
1	Reaction
2	Reaction Type
7	Reference
6	Source Tissue
1	Substrates and Products (Substrate)
4	Synonyms

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Application on EC 3.4.22.B32 - calpain 12

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APPLICATION

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

medicine

Homo sapiens

-

in a patient with a paternal missense mutation (c.1511C>A; p.P504Q) and a maternal deletion due to activation of a cryptic splice site in exon 9 of the gene (c.1090_1129del; p.Val364Lysfs*11), filaggrin expression is almost absent in the skin

754354