3.1.4.56: 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase

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For detailed information about 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase, go to the full flat file.

Reaction

Synonyms

MJ0837 gene product, MptB

ECTree

3 Hydrolases

3.1 Acting on ester bonds

3.1.4 Phosphoric-diester hydrolases

3.1.4.56 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase

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Results	in table
26	AA Sequence
1	Cloned(Commentary)
5	Metals/Ions
2	Molecular Weight [Da]
1	Natural Substrates/ Products (Substrates)
1	Organism
1	Oxidation Stability
6	Pathway
2	pH Optimum
1	pH Range
3	Protein Variants
1	Purification (Commentary)
4	Reaction
1	Reference
5	Specific Activity [micromol/min/mg]
7	Substrates and Products (Substrate)
2	Subunits
2	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]
1	Temperature Stability [°C]

Temperature Stability

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Temperature Stability on EC 3.1.4.56 - 7,8-dihydroneopterin 2',3'-cyclic phosphate phosphodiesterase

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70 - 100

Methanocaldococcus jannaschii

Q58247

after heating for 45 min in absence of Mn2+ the activity of the enzyme drops about 30% from the 70°C heated sample to the 100°C heated sample. In the presence of Mn2+, in the case of 45 min heating the activity of the enzyme increases about 53%from the 70°C heated sample to the 100°C heated sample. In the case of 2.5 h heating the activity of the enzyme drops about 26% from the 70°C heated sample to the 100°C heated sample. Adding Mn2+ to the enzyme increases the temperature stability of the protein

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