2.7.1.31: glycerate 3-kinase

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For detailed information about glycerate 3-kinase, go to the full flat file.

Reaction

Synonyms

AtGLYK, D-glycerate 3-kinase, D-glycerate kinase, D-glyceric acid kinase, GK, glycerate kinase, glycerate kinase 1, glycerate kinase 2, glycerate-3-kinase, Glyctk, GLYCTK gene, GLYCTK1, GLYCTK2, GLYK, kinase, glycerate (phosphorylating), More, NosGLYK, OsGLYK, ScGLYK

ECTree

     2 Transferases

         2.7 Transferring phosphorus-containing groups

             2.7.1 Phosphotransferases with an alcohol group as acceptor

                2.7.1.31 glycerate 3-kinase

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Results	in table
2	Activating Compound
4993	AA Sequence
1	CAS Registry Number
6	Cloned(Commentary)
1	Crystallization (Commentary)
14	Disease/ Diagnostics
1	Expression
2	General Information
1	General Stability
28	Inhibitors
26	KM Value [mM]
8	Localization
56	Metals/Ions
10	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
29	Organism
11	Pathway
7	PDB ID
14	pH Optimum
3	pH Range
4	pH Stability
2	Protein Variants
19	Purification (Commentary)
3	Reaction
1	Reaction Type
29	Reference
41	Source Tissue
9	Specific Activity [micromol/min/mg]
7	Storage Stability
44	Substrates and Products (Substrate)
4	Subunits
28	Synonyms
1	Systematic Name
5	Temperature Optimum [°C]
2	Turnover Number [1/s]

Engineering

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Engineering on EC 2.7.1.31 - glycerate 3-kinase

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PROTEIN VARIANTS

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

F483S

Homo sapiens

Q8IVS8

naturally occuring mutation, the homozygous mutation c.1448delT, p.Phe483SerfsX2 in the GLYCTK gene causes D-glyceric aciduria, but is not involved in nonketotic hyperglycinemia (NKH) as a secondary phenomenon, the latter is caused by mutations in the AMT gene (EC 2.1.2.10), also harbored by the patient

759778

additional information

Arabidopsis thaliana

-

construction of inactive T-DNA insertion knockout mutants, which are not viable in normal air, but grow under elevated CO2 concentration, and show high accumulation of glycerate, overview

660135