2.1.1.7: nicotinate N-methyltransferase

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For detailed information about nicotinate N-methyltransferase, go to the full flat file.

Word Map on EC 2.1.1.7

2.1.1.7

pyridine

corticosterone

methanesulfonate

aureus

hydrochloride

mungbeans

agonists

prolactin

mononucleotide

phaseolus

seedlings

opiate-induced

pituitary

radioimmunoassay

n-methylnicotinate

luteinizing

ethylketocyclazocine

morphine

opiate

neuroendocrine

Reaction

Synonyms

At3g53140, furanocoumarin 8-methyltransferase, furanocoumarin 8-O-methyltransferase, methyltransferase, nicotinate, NANMT, nicotinate methyltransferase, nicotinic acid methyltransferase, NNMT, S-adenosyl-L-methionine:nicotinic acid-N-methyltransferase, T4D2.70, trigonelline synthase

ECTree

2 Transferases

2.1 Transferring one-carbon groups

2.1.1 Methyltransferases

2.1.1.7 nicotinate N-methyltransferase

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Results	in table
7	AA Sequence
1	CAS Registry Number
1	General Information
4	General Stability
15	Inhibitors
1	kcat/KM [mM/s]
8	KM Value [mM]
1	Metals/Ions
3	Molecular Weight [Da]
6	Natural Substrates/ Products (Substrates)
7	Organism
1	Oxidation Stability
2	Pathway
1	PDB ID
5	pH Optimum
3	pH Range
2	Purification (Commentary)
1	Reaction
1	Reaction Type
7	Reference
8	Source Tissue
5	Specific Activity [micromol/min/mg]
4	Storage Stability
13	Substrates and Products (Substrate)
1	Subunits
11	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Range [°C]
1	Turnover Number [1/s]

General Information

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General Information on EC 2.1.1.7 - nicotinate N-methyltransferase

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physiological function

Arabidopsis thaliana

Q9SCP7

homozygous mutant lines show marked reductions in N-methylnicotinate accumulation in inflorescence tissues, whereas the levels of nicotinate, glucosylated nicotinate, nicotinate mononucleotide, and NAD are increased. Overexpressing lines have higher N-methylnicotinate content and lower nicotinate, glucosylated nicotinate, nicotinate mononucleotide, and NAD contents

758041