1.14.12.22: carbazole 1,9a-dioxygenase
This is an abbreviated version!
For detailed information about carbazole 1,9a-dioxygenase, go to the full flat file.
Word Map on EC 1.14.12.22
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1.14.12.22
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ferredoxin
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rieske
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resinovorans
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carac
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carbazole-degradation
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dibenzo-p-dioxins
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dibenzofurans
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fluorene
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aromaticivorans
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nocardioides
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dianhydride
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dibenzothiophene
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polyimide
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janthinobacterium
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stipes
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degradation
- 1.14.12.22
- ferredoxin
-
rieske
- resinovorans
- carac
-
carbazole-degradation
- dibenzo-p-dioxins
- dibenzofurans
- fluorene
- aromaticivorans
-
nocardioides
-
dianhydride
- dibenzothiophene
-
polyimide
- janthinobacterium
-
stipes
- degradation
Reaction
Synonyms
CarAa, CarAc, carbazole dioxygenase, CARDO, CARDO-F, CARDO-R
ECTree
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Cofactor
Cofactor on EC 1.14.12.22 - carbazole 1,9a-dioxygenase
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ferredoxin component CarAc acts as a mediator in the electron transfer from ferredoxin reductase CarAd to terminal oxygenase CarAa. It contains a Rieske [2Fe-2S] cluster, which is located at the tip of the cluster-binding domain, where it is exposed to solvent
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Ferredoxin
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ferredoxin component contains two Rieske [2Fe-2S] clusters
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NADH
both NADH and NADPH are effective as electron donors for His-tagged ferrdoxin reductase CarAd. The ratio kcat/Km for NADH is 22.3-fold higher than that for NADPH in the 2,6-dichlorophenolindophenol reductase assay
NADPH
both NADH and NADPH are effective as electron donors for His-tagged ferrdoxin reductase CarAd. The ratio kcat/Km for NADH is 22.3-fold higher than that for NADPH in the 2,6-dichlorophenolindophenol reductase assay