1.1.1.325: sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
This is an abbreviated version!
For detailed information about sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming), go to the full flat file.
Reaction
Synonyms
MDSPR, sepiapterin reductase, SPR
ECTree
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Substrates Products
Substrates Products on EC 1.1.1.325 - sepiapterin reductase (L-threo-7,8-dihydrobiopterin forming)
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REACTION DIAGRAM
6-pyruvoyl-5,6,7,8-tetrahydropterin + 3 NADPH + 3 H+
L-threo-7,8-dihydrobiopterin + 3 NADP+
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-
-
-
?
6-pyruvoyl-5,6,7,8-tetrahydropterin + NADPH + H+
L-threo-7,8-dihydrobiopterin + NADP+
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-
-
-
?
L-threo-7,8-dihydrobiopterin + NADP+
sepiapterin + NADPH + H+
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-
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-
r
sepiapterin + NADPH + H+
L-threo-7,8-dihydrobiopterin + NADP+
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-
-
?
sepiapterin + NADPH + H+
tetrahydrobiopterin + NADP+
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no stereochemic specification in the publication
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additional information
?
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the enzyme also shows activity with D-threo-dihydrobiopterin, L-threo-dihydroneopterin, and dihydrotepidopterin, and low activity with L-erythro-dihydrobiopterin
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?