1.1.1.187: GDP-4-dehydro-D-rhamnose reductase

This is an abbreviated version, for detailed information about GDP-4-dehydro-D-rhamnose reductase, go to the full flat file.

Reaction

GDP-alpha-D-rhamnose
+
NAD(P)+
=
GDP-4-dehydro-alpha-D-rhamnose
+
NAD(P)H
+
H+

Synonyms

GDP KR reductase, GDP-4-keto-6-deoxy-D-mannose reductase, GDP-4-keto-D-rhamnose reductase, guanosine diphosphate-4-keto-D-rhamnose reductase, RMD, tld gene product

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.187 GDP-4-dehydro-D-rhamnose reductase

Systematic Name

Systematic Name on EC 1.1.1.187 - GDP-4-dehydro-D-rhamnose reductase

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SYSTEMATIC NAME
IUBMB Comments
GDP-6-deoxy-alpha-D-mannose:NAD(P)+ 4-oxidoreductase
The enzyme, which operates in the opposite direction to that shown, forms a mixture of GDP-alpha-D-rhamnose and its C-4 epimer, GDP-6-deoxy-alpha-D-talose. cf. EC 1.1.1.281, GDP-4-dehydro-6-deoxy-D-mannose reductase and EC 1.1.1.135, GDP-6-deoxy-D-talose 4-dehydrogenase.