Reaction catalyzed by phthioceranic/hydroxyphthioceranic acid synthase (2.3.1.287)
7
+
palmitoyl-[(hydroxy)phthioceranic acid synthase]
+
14
NADPH
+
14
=
7
+
C37-phthioceranyl-[(hydroxy)phthioceranic acid synthase]
+
14
NADP+
+
7
CoA
+
7
H2O
7 (S)-methylmalonyl-CoA
+
palmitoyl-[(hydroxy)phthioceranic acid synthase]
+
14 NADPH
+
14 H+
=
7 CO2
+
C37-phthioceranyl-[(hydroxy)phthioceranic acid synthase]
+
14 NADP+
+
7 CoA
+
7 H2O