Reaction catalyzed by vitamin D 1,25-hydroxylase (1.14.15.22)
+
2
reduced ferredoxin [iron-sulfur] cluster
+
2
+
=
+
2
oxidized ferredoxin [iron-sulfur] cluster
+
H2O
calcidiol
+
2 reduced ferredoxin [iron-sulfur] cluster
+
2 H+
+
O2
=
calcitriol
+
2 oxidized ferredoxin [iron-sulfur] cluster
+
H2O
