Reaction catalyzed by 10-deoxymethynolide synthase (2.3.1.239)
+
5
+
5
NADPH
+
5
=
+
6
CoA
+
6
+
5
NADP+
+
2
H2O
malonyl-CoA
+
5 (2S)-methylmalonyl-CoA
+
5 NADPH
+
5 H+
=
10-deoxymethynolide
+
6 CoA
+
6 CO2
+
5 NADP+
+
2 H2O
