Reaction catalyzed by thiamine phosphate synthase (2.5.1.3)
+
=
+
+
4-amino-2-methyl-5-(diphosphomethyl)pyrimidine
+
2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate
=
diphosphate
+
thiamine phosphate
+
CO2