Reaction catalyzed by catechol O-methyltransferase (2.1.1.6)
+
=
+
+
S-adenosyl-L-methionine
+
(3,4-dihydroxyphenyl)acetic acid
=
S-adenosyl-L-homocysteine
+
(4-hydroxy-3-methoxyphenyl)acetic acid
+
(3-hydroxy-4-methoxyphenyl)acetic acid
