Reaction catalyzed by norbelladine O-methyltransferase (2.1.1.336)
2
+
=
2
+
+
2 S-adenosyl-L-methionine
+
(-)-norepinephrine
=
2 S-adenosyl-L-homocysteine
+
4-O-methylnorepinephrine
+
3-O-methylnorepinephrine
