Reaction catalyzed by 3'-phosphate/5'-hydroxy nucleic acid ligase (6.5.1.8)
(ribonucleotide)n-2\',3\'-cyclophosphate
+
5\'-hydroxy-(ribonucleotide)m
+
+
H2O
=
+
+
(ribonucleotide)n-2',3'-cyclophosphate
+
5'-hydroxy-(ribonucleotide)m
+
UTP
+
H2O
=
(ribonucleotide)n+m
+
UMP
+
diphosphate
