Reaction catalyzed by 3-methyl-2-oxobutanoate hydroxymethyltransferase (2.1.2.11)
+
+
H2O
=
+
5,10-methylenetetrahydrofolate
+
3-methyl-2-oxobutanoate
+
H2O
=
tetrahydrofolate
+
2-dehydropantoate