Reaction catalyzed by 3'-phosphate/5'-hydroxy nucleic acid ligase (6.5.1.8)
(ribonucleotide)10-3\'-phosphate
+
5\'-hydroxy-(ribonucleotide)10
+
=
(ribonucleotide)20
+
+
(ribonucleotide)10-3'-phosphate
+
5'-hydroxy-(ribonucleotide)10
+
ITP
=
(ribonucleotide)20
+
IMP
+
diphosphate
