Reaction catalyzed by protein acetyllysine N-acetyltransferase (2.3.1.286)
NAD+
+
=
+
+
NAD+
+
[histone H4]-N6-acetyl-L-lysine8
=
nicotinamide
+
[histone H4]-L-lysine8
+
2'-O-acetyl-ADP-ribose
