Reaction catalyzed by tetracenomycin A2 monooxygenase-dioxygenase (1.14.13.200)
+
2
+
2
NAD(P)H
+
2
=
+
2
NAD(P)+
+
H2O
tetracenomycin B2
+
2 O2
+
2 NAD(P)H
+
2 H+
=
8-demethyl tetracenomycin C
+
2 NAD(P)+
+
H2O