Reaction catalyzed by protein-lysine desuccinylase (NAD+) (2.3.1.B43), protein acetyllysine N-acetyltransferase (2.3.1.286)
NAD+
+
=
+
+
NAD+
+
[histone H4]-N6-acetyl-L-lysine16
=
nicotinamide
+
[histone H4]-L-lysine16
+
2'-O-acetyl-ADP-ribose
