Reaction catalyzed by steroid 21-monooxygenase (1.14.14.16)
+
+
=
+
+
H2O
progesterone
+
[reduced NADPH-hemoprotein reductase]
+
O2
=
16alpha-hydroxy-progesterone
+
[oxidized NADPH-hemoprotein reductase]
+
H2O
