Reaction catalyzed by 11beta-hydroxysteroid dehydrogenase (1.1.1.146)
+
NADP+
=
+
+
NADPH
7beta-hydroxydehydroepiandrosterone
+
NADP+
=
7alpha-hydroxydehydroepiandrosterone
+
7-ketodehydroepiandrosterone
+
NADPH
