Reaction catalyzed by carboxypeptidase A (3.4.17.1), carboxypeptidase A2 (3.4.17.15)

		+		H2O	=			+
	methotrexate-alpha-(1-naphthyl)alanine	+		H2O	=		methotrexate	+		(1-naphthyl)alanine