Reaction catalyzed by alpha-N-acetylneuraminate alpha-2,8-sialyltransferase (2.4.3.8)

		+			=			+
	CMP-alpha-N-acetylneuraminate	+		alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide	=		CMP	+		alpha-N-acetylneuraminyl-2,8-alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide