Reaction catalyzed by hydroxymethylglutaryl-CoA reductase (1.1.1.88)
+
CoA
+
2
NAD+
=
+
2
NADH
+
2
(R)-mevalonate
+
CoA
+
2 NAD+
=
(S)-3-hydroxy-3-methylglutaryl-CoA
+
2 NADH
+
2 H+
