Reaction catalyzed by prostaglandin-F synthase (1.1.1.188), 3(or 17)alpha-hydroxysteroid dehydrogenase (1.1.1.209)

		+		NADPH	=			+		NADP+
	5beta-androstane-3,17-dione	+		NADPH	=		5beta-androstan-3alpha-ol-17-one	+		NADP+