Reaction catalyzed by 16alpha-hydroxysteroid dehydrogenase (1.1.1.147)
+
NAD(P)H
+
=
+
NAD(P)+
3-hydroxy-estra-1,3,5(10)-triene-16,17-dione
+
NAD(P)H
+
H+
=
3,16alpha-dihydroxy-estra-1,3,5(10)-triene-17-one
+
NAD(P)+
