>Q8KHE4|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Lentzea aerocolonigenes|Swiss-Prot
MGARVLVATTPGDGHVNPMVPVAQEMVSRGHEVRWYTGKAFRSTVERTGARHEPMRDAHD
FGGMPREEAFPQHAGLTGITGMIAGFRDIFIEPAADQMTDLLALLEDFPADVLVTDETFF
GAGFVSERTGIPVAWIATSIYVFSSRDTAPLGLGLPPSSSRLGRLRNTVLKQLTDRVVMR
DLRRHADVVRDRVGLPRIRKGAFENIMRTPDLYLLGTVPSFEYPRGDMPPEVRFVGPFVS
PAPPDFTPPAWWGELDSGRPVVHVTQGTVANDAERLLLPAIRALAAEDVLVVATTGAPLE
LEPMPANVRVERFIPHHALLPHVDAMVTNGGYGGVNTALAHGVPLVVAAATEEKHEVAAR
VSWSGAGVHLKKRRLSERDIRRAVRAVLDEPRFRVHAARLRDEYAARDAVVDAVDLIEGL
V
>K5B8Q2|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycolicibacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 / 3849)|TrEMBL
MRVAVVAGPDPGHAFPAIALCLRLSAHGDTPTLLTGVERLAVARAAGVDAIELLGLSAAE
TDDDSDAGAKIHERAARMAVLNAPQLTELAPDLVVSDAITACGGMAAELIGLPWVELNPH
PLYLPSKGLPPIGSGLAPGVGWRGRLRDAVLRALSARSYRRGLRQRAAARRGIGLPGAGP
GPRRRLIATLPALEVPRPDWPAEAVLVGPLHFEPTATTLPIPPGTGPVVVVAPSTATTGA
HGVAEVALQALTPGETLPDGARLVVSRLSGPELAAPPWAVVGLGRQDELLSHADLVICGG
GHGMVSKALLAGVPLVVVPGGGDQWEIANRVVRQGCGELVRPLTADALVAAVQRVLGSAS
YREAARRAGATVTQVADPVRVCHESLSDQA
>A0A0F2E6I2|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus infantis|TrEMBL
MKRIKIDVVIVPLSGHLYPTMNLLLPLLDNPQYEIRLFTGPQKKAVCEASGFQVVPILED
HIEEFESAANNSEQLGILSAYHQLSASIDLINVVSDQLLDEWQKNRPDIVIADFITLSGG
LVANQLGIPWITTMATQFVLETTDGPPCLIGGMGSPKNAWDSAVQFLGRKGTRLVKRIVS
FSFRDRLKRYNFRLYNQLDQETIYSPYSILGIGMKEVELKKGFPEHYKWVGPSGASVEVG
EDYPLDLSPFMDRKKVLVTCGTQLAWAKENLIYQATQLAKSHPDCHFFVTRGVGGEPFQC
ENLMENLSVVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIYGKPALILPHDYDQFDYAVRG
VEAGVALTANKEDTRAIGLAFEKLIAKEDWSELEILRQAAQSYHPTEILESEIHRLLADK
EKE
>A0A4V3HUQ6|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycobacteroides franklinii|TrEMBL
MRVAVVAGPDPGHAFPAIALCLKFAAAGHDPVLLTGTRWLEQARAVGLESLELLGLQPRV
ADDDTDAGAKIHQRAAHMALANLDQLRDLAPDLVVSDVITACGGMAAELLGVPWVELNPH
PLYLPSKGLPPLGSGLAPGEGWRGRLRDGVMRRLTQRSIDEGLRQRSQARVAIGLPARDP
GPVRRLIATLPALEVPRPDWPREAVLVGPLHWEPTDVVLQPPSGPGAVVVIAPSTAFTGA
EGMTELAVQALDSAGARVVVSALDPPASGLPAWAVAGLARQDLLLAGADLAICGGGHGFL
SKALLAGVPAVVVPGGGDQWELANRVVRQGSAELVRPLNRDSLAAAIGRVLGERRYTEAA
RRAAAGAVDVTDPVRVCQDAVTALK
>A0A517TNQ3|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Planctomycetes bacterium MalM25|TrEMBL
MLCLLTALGSYGDVYPMVGLGEALRRRGHEVRLIANPHFESVVNGAGLQLVPVSSAEEYD
EFTACRELWSPKEGLRLIFKRGAMAVLEELYEKLGQLHCPGETVIAAHGLDLASRVFAET
HDAPVAAAVFAPMAIWSNQSPPRLPSGVAWPGAPRWLHRLQFTAAEHLILRRLAVDELEA
FRSQQGLAPLRGGYWDWYYGVAPPLGLFPDWFVSPDGRTPADWPPGSATTGFPFGDALSD
PALSPELLRFLDAGEPPIVFTPGSAMRFGERFFAAAVGACQRLNRRGVLLTKYSEHLPND
LPDTILAPGFTPLARLLERTAAFVHHGGIGSSARGLAAGVPQLIQPMAFDQYDNAWRLRR
LGVAEELPPKRFTARRVAEKLDRLLSDPEVSRACARWAGRVDREAALEAACEHLESRLVG
GSD
>A0A2I2L1J2|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Frankia canadensis|TrEMBL
MGCLMARFLFATMPAVGHTSPAIPVARELVARGHGVRWYGGAAFADQIARTGAAFHPITE
SQHDHSVHGLDARYPHRRELSGLRKLQFDMTYGFAAPVAGQVRDLTALLDKEPADVIIGD
TGFIGGTIVQELGGPALAGFGISVLGFPSRDLAPFGFGLSPARGPLGRVRNRVLDKATRR
ILFRGMTAEVNVARRAFGLPPTSAAVYDFALETRLYLQFSTPGFEYPVTDRPSQVRFVGP
PRQETDRHWQRPDWWDDLSGDRRVVLVTQGTVATDPSQLLRPAIDALGPEDDLLVVAVTG
GADPSELGAVPANTRVARFIPFDLLLPHTDVFVTNGGYGGVQLALSHGVPVVGAGKTEDK
GEVNARVAYSGVGIDLRSQTPGPDRVRAAVRQVLGDIGYTLAAGRLRAEIDAAGREQRAA
DLLEELARQQSTGGARVAQGD
>A0A0N0XK97|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Amantichitinum ursilacus|TrEMBL
MSRILFAWELGDNHGHLWRLLPIALAARAQGHDISFALRAMRSAQRYLTPRSVPFMACPN
PYDVPALGRDPSTYADVLALNGATDVDLLGGMVRGWRQLYQLVKPDVVVIDHAPTALMAS
RVAGIRSVQIGTGFAIPPSLMPAPCYRAWDSDIEARQHTQAAVEHAVASVCEMPLSTALQ
ADHTRLLSLPELDHYATVRPAGALFLGGMPQPPAGQAVQWHTDKTHILVYLQNGDWLGTV
LEGLVNSEAEVIAVVPGIALAQAAQFPELRIYTQPVQLEPLLPRCDLIISHGGHGTALNA
LRAGVPLLMLPQHMEQLLVTERVAVAGAGLGVFPTHIESSFEHVLFTLLMSPQYRAAAQQ
VAARYAEWRDEFALQQMLAVLNTACAEAA
>A0A7K0C445|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Actinomadura macrotermitis|TrEMBL
MRGRRVQVPSLLDDIPASLGGTAAAPPPVEEGGGRRRFLFAVPPLVGHVNPAVSVASELA
ARGHRVAWVGHKTMLEPLLKPGSRIFPAGDAEFAKRLTAAREQWRGLRGPAALKFLWEEF
IVPLGHAMLPGVQEAIGKFRADVVVGDQQVLAAPVAARLCDVPWATSATTSAEFTRPLAG
MPLVEEWVRDQIGDFQLDHGIEDLLDLRFSDHLTLVFTTSALLGDTSFFPDHFAFVGPAL
SRPPGGDFPWEWLQEGRPAVLVSLGTVEGAAGARFLQAAAEAVADLDVQAVFVAPDRVLR
DPPPNVLVRPHVPQLELLAQMSAVVTHGGHNTVCESLAHGLPLVVAPIRADQPIIARQVE
TAGAGRTVRYGRAGAAELREALVDVLTGTAYREAAGRVRESFAAAGGAAEAASRLEKLA
>A0A2X3N3F6|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Frankia sp. Ea1.12|TrEMBL
MARFLFATVPAVGHTVPALPIARALIERGHTVRWYTGVAFAEKITAVGAKFHPITDPDFD
YSLVGLEEHYPRRRELSGLKKLQFDLVQGFSKPVPNQVRDLMALLQEEPADAVVTDTAFI
GGVLLQELGGPPVAGFGISVLPFPSRDLAPFGMGLAPATGPLGRLRNKALAGFTRQVVYR
PVTAEINRTRRMLGLPATAGTIFSYPLATQLYLQFSPPSFEYDVSDLPGQVAFVGPPRPP
VDPGWEPPSWWHELSGRRVVLVNQGTVATDADQLIRPALAGLADEDVLVVAVTGGSDPAE
LGPLPANARVERFIPFDQLLPRVEVFVTNGGYGGVQLALSHGVPIVGAGRTEDKIEVNAR
VAASGVGVNLRTQTPEPDVIRGAVAKVLADSRYATAARRMQAEIAQAGRETRAAELLEQL
ADGSTPGRSELVSGTTGDRLHPDHAAF
>A0A1C0U291|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Photorhabdus australis subsp. thailandensis|TrEMBL
MACIVIAAIASPGHFYPMLKVAQSLISQGHQITLFTGAVFRQQVEAINAQFVAFDERIDY
DYRHFVQHFPLRAQLPPGNLQLALSLKHIFAEPIPFLSQQLQQIIREQQAELVITENYFF
SILPLLQEERICRLPVIILGLGPLSYSSKDTVLFGPRIPPVLIPPELTHEQLVDEKTRQL
IAEVQTYFDDALIQSGCSALTRPFNDAIILGADRFLQLSTLAFEYEREELPDTVHFIGPI
LDSTPITEAPHLWEDDDPRPLVIVTQGTISNSDLNQLLLPTLRALATLPVRVLATTGGRA
VETLNEVIPENACVKDFISFERWLPKAELLISNGGYGTINYALSHGVPLLIADAGESKQE
TAFRVILAGCGISLNTAYPTETALRQSVEKILNTNLFKQRAKIVQQDYARHNALAEISKH
VEQLILERSRIN
>A0A1C0U2C1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Photorhabdus australis subsp. thailandensis|TrEMBL
MARIVIAAVATPGHVYPMLKVTQSLITQGHQVTVFTGVLFRQHVEDLNATFIPFDEKIDF
DYRHLKQRFPDRAHVPPGNLQMALAFKDFFCSPIPLLDSQLQQIIHEQQAELLIAENCFY
GILPLLQKEKSHRLPVIIIGITPLAYSSKDSIFWGPRIPPALLPSELTHEQLVDEEARQL
ITEVQNNFNDALAQSGCSTLTRFFNDEVIFSSDRFLQLSTLAFEYPREGLPDTVHFIGPL
PNPAPKIESPQLWEDDDPRPLVVVTQGTMSNTDLNQLILPTLRALATLPVRVLATTGGRS
VEILQENIPDNAHIEEFISFEDWLPKASLLITNGGYGTINYALNHGTPLLIADTGEGKQE
TAFRVVWAGCGINLDTAQPAESQLKQTVENMLSTNLFKQRAQIVQDDYASHDALAAISNH
AEQLILERNRAN
>A0A221W2R4|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Actinoalloteichus hoggarensis|TrEMBL
MTRVLIAAVPIHGHVTPMRAIARNLVERGYPVTFLTGQDFRESVERTGARFRSLPSEADL
TGPVNELFPERDTGALRREQIEFDMRLTIHGLSGQHAAMQEILAEADGEPVVLVHETLFM
GGWPVRLGAPGLRPAGVVGIGVIPVPISSIDHAPWGMGLPPDSSSEGRARNRFLNDVAAA
ELQAGVQRELAAGLAALGATEEPPLMFDGLVAMPDRFLQLTIGSMDYPRSDAPPRLRHVG
ALPAEPPEDVELPEWWDELITASRVVVVTQGTLANADLSRLIEPAVRALADLDALVVVTT
GSDVIPDRLPANARAARYLPFDLLLPHADVLISNGGYGGVHRALWHGVPMVLAGDTEDKV
EVGALAAWAGAAINLATGDPDEADIRKAVDAVLTDPTHARRAEELRAECLRQDPHGTIAA
AVEELARRTE
>A0A221W4T6|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Actinoalloteichus hoggarensis|TrEMBL
MKILVYAYGTRGDVQPYLALAAALGRAGHEAILSAPARFETLASAHGVEFRGRDDEWLGI
LEDPDVRRILAMGGMRKALDKDARRRARTRLHDDFRRLFPKILADTAAAADSDVDLVVHS
QEYVDQGGQIAEKLGVPSVLALLHPFIVPSWEYPSGLFPFDTRLPRLLNRLSHVPLRFLR
LERRTLARWRSEDLGLPPRPRSHDMQRRPDGGRVTVLHGFSRHVVTPASDWPSEVHTTGF
WLLPGGDSWTPPPALAAFLDAGEPPVFIGFGSLAGLDPRETGRAVVAAVRAAGVRAVVSS
GWGSIEIDDPPEDVLIVEEVPYDRLFPRMRAVVHAGSAGAMNEALAAGVPQAACPLHREQ
ELWGNRVHRLGIGPAPVRQRDLNAAVLTEIIRQVVTDRTMAERAARMRTLVRAEDGARVA
ATVLTDLFDATATHTG
>A0A100J3W5|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces acidiscabies|TrEMBL
MSGFLFVVPPLTGHVNPAVGVAARLAARGHRVAWVCPDRELVRRLAGADAVVFGCGDELS
RITHAQAASHRPAGIRGPEALKFLWERFLLPLAEAMAPGVRRAVEVFRPDVVIADQQAFA
GALVAERAGIPWATSATTTAEFMDPLAGLPKVREWIEARLDALRRAVGDASKAADPRFSP
HLVIGFSTPELAGDIKGVQWVGPSVTGRPDAGGFPWEWLDPDRATVLVSLGTANADAGER
FLAVCRDVARERAGRLRAVVVDPGGVLGAGTDDNVLIVPSVPQIALLAKGVDAVVCHAGH
NTVCEALWYGVPLVVAPIRDDQPVIAGQVVAAGAGVRVRFGRVGAQQLGAALDAVLDEPS
YRARAARVGAAFRAAGGADAAAVHLEELAERSRA
>A0A291DB70|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus oralis|TrEMBL
MRKIKIDVVVVPLSGHLFPTLNLLAPLLKDPLYEIRLFTGPQRKTVAEEMGFRVISILEN
CVDEFERVANNEGQLNLFSAYRQLSASLDLINVVSDQLVQEWQENRPDIVIADFITLSGG
LVAEQLNIPWITTMATQFAIETTDGPPCFFGGLGSPKTSFQSGLQWLGRKGTRLGKRIVS
FLLRERLKRYDFKLYNQKGQETIYSPYSILGIGMKELELKSGFPEHYLWVGPFGSSIERA
ENYPLDLSPYAGYKKVLVSCGTQLAWAKDNLLCQTQQLAEAHPDCHFFVTLGFGGQDFQC
EELMDNVSVVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIYGKPALILPHDYDQYDYAVRG
LEAGIALTAKREDTEAIGRAFDELLARDDWADLNKLSRAAQIYQPTEILKSEIHRLLGDK
EK
>A0A1X0LEH1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycobacterium persicum|TrEMBL
MRVAVVAGPDPGHSFPAIALCQRFQAAGDAPTLFTGVEWLDAAHAVGVDAVELDGLTATD
EDLDAGARIHRRAAEMAVLNAPALRELAPDLVVSDVITACGGLAAELVGIPWIELNPHPL
YLPSKGLPPIGSGLARGTGIRGRLRDATMRALTGRSWRAGLRQRAAVRVQIGLPARDPGP
LRRLIATLPALEVPRPDWPAEAVVVGPLHFEPTDRVLPVPPGSGPVVVVAPSTAVTGTAG
LVEVALGCLTPGDTLPEGSRVVVSRLGGGDLPVPAWAVVGLGNQAELLTHADLVICGGGH
GMVAKTLLAGVPLVVVPGGGDQWEIANRVVRQGSGRLVRPLTAEALVAAVNEVLSSPGYR
RAAQQAAAGAAAVADPVRVCHEAL
>A0A7G6UZT1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Burkholderia cenocepacia|TrEMBL
MKRILFCVVPEKGHVNPCIGPAQHLRASGCDVAFYAPADISEQLDGAGDFAFVGPRETPE
RHDLSRGASFAANIRDADWLRHWIRTLLIDLAPAQVDGIRAVLRDWRPDVVVIDPLLYAA
AIAAELEGLPWVSMSNSLNPVLPDDLDSELLRTVRWLEPERTRLFARYGLDARFRGCDVL
SPHLTLAFTTDALVGAPPLGVELVGPAMPSGPRGDETAFPWERVDADRPLVYMSLGSQLY
YHPEVFAKVIDATRATSAQLVLSVGELVDSDLLPAADERVLAVRYAPQLALLRRTHAFVS
HGGANSVMESLACGVPMLLSPFCNDQFHSAHFVERAGAGCVLDLQRAGVTDITDALERLL
RAGPLREQAARIRDSYAACDGSAQAARLIRALASGSRLATAS
>A0A7G6V2I5|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Burkholderia cenocepacia|TrEMBL
MKLVIATYGTEGDTRPLAALGRALLDAGHEVRLLADAATLGSAAALGVPSAPLSGDIRRA
IAPEGALADAVRGRGGFNDTSKALAAIANANTAAWMREVADASAGCDALLVSGLVSFVGL
SVAEYRGIPAIGTGMIPITPTAEFASPFLPPGKLPRWLNRASHRLVNALLWQAFRKSTNA
ARAGVCGLPPRQHVWTDHPMLYGVSPALLSGPADWPANVQACGQWRIDARAWAPSPELAA
FLDAGEPPVYIGFGSMAGFDRAAMAAALTQALAGRRALFYPGWSGIDASLLPAHVRVIGD
TPHDWLFPRVAMAVHHGGSGTTHSAARAGIASVVVPFAGDQFFWANRLQRLGVAAAPVAG
RRMEAVALARAIAFAERGETKARATALGARLAQEDGLKRAVSAIERWVRPRAR
>A0A0M2H0E1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Microbacterium trichothecenolyticum|TrEMBL
MHEWMPHDELFPEASLVVGHGGHGTTLAALAHGIPVRTLPLEPTSDQPRIGRAVARAGVG
ATMSRRTEPAAIRRAIRRTLADDRTGGRAQRLGVAIRAFDGPRRAADVLELYAVAPR
>A0A0J6W4V8|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycolicibacterium chlorophenolicum|TrEMBL
MVWRMRVAVVAGPDPGHAFPALALCLRFAAAGDSPTLLTGTRWLDEARAQGIDAVELDGL
RVMTGDDDADAGAKIHERAGRMAVLNTDRIAALKPDLVVSDSITTCGGLAADLLGVPWIE
LNTHPLYRPSAGLPPLGSGLAPGTGIRGRARDAVLRALSARSWREGLRQRAAVRVEIGLP
ADDPGPLRRLIATLPAMEVPRPDWPAEAVVVGPLHYEPTTSVLTLPDGEGPVVMVAPSTA
STGAVALADLALQTLVPGDVLPAGARVAVSQLHAPTGEVPPWAVVGLGRQDELLGRTDLL
VCGAGHGIVSKALLAGVPMVVVPGGGDQWEIANRLVRQGSAQLVRPLTRETLGAAVREVL
GTPRYRDAARRAGATVAAVADPVRVCHDALRTGK
>A0A1C3H8K2|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Serratia marcescens|TrEMBL
MAAVATPGHVYPMLAIARHLIAQGHQVRVMTGALFRERAEAVGASFVPFDAQVDFDYRHL
EEHFPERAALPPGNAQMALALKDFFAAPIPLLDRQLRAAIAAEKTDLLMVENCFYGVLPL
LQSAERPPVFGIGVTPLSYSSRDAIFYGPRIPPALLPQALTREQLVDEETRVLLDEVQQS
FDAALVQAGGRALNRPFTDALIGGCERFLQLATTALEYERDDLPSGVRFVGPLRSGGQPA
AEETLWEKDDRRPLVIVSQGTLANVDLHQLIVPTLQALAHLPVRVLATTGGRATEGLMEA
LPGNARVREFISFERWLPEAALLITNGGYGSINYALDSGVPLIVAGTGEDKLEAAARVVA
AGCGISLHTSTPSAEQILAAATRILQQPIYRQRAALVREDYARHDALTAIANEVAAITA
>A0A0J6ZE31|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycolicibacterium chubuense|TrEMBL
MVWRMRVAVVAGPDPGHAFPALALCLRFAAAGDSPTLLTGTRWLDEARAQGIDAVELDGL
RVMTGDDDADAGAKIHQRAGRMAVLNTDRIAALEPDLVVSDSITTCGGLAADLLGVPWIE
LNTHPLYRPSKGLPPLGSGLAPGTGIRGRARDAVLRALSARSWRAGLRQRAAVRVEIGLP
ADDPGPLRRLIATLPAMEVPRPDWPAEAVVVGPLHYEPTTSVLTLPDGDGPVVMVAPSTA
STGAVALADLALQTLVPGDVLPAGARVAVSQLHAPTGEVPPWAVVGLGRQDELLGRTDLL
VCGAGHGIVSKALLAGVPMVVVPGGGDQWEIANRLVRQGSAQLVRPLTRETLGAAVREVL
GAPRYRDAARRAGATVAAVADPVRVCHGALDAGK
>A0A6I1Z8R2|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces sp. RB17|TrEMBL
MSAFLFVVPPLTGHINPAVGVAARLAAHGHRVAWVCADPALVRRLAGPDAEVFGCAGPVP
GAEGAVRPPDLRGAEALKFLWEWYLLPLADAMAPGIRAAAEAFRPDVVVADQQAFAGALV
AERLGLPWATSATTSAEFTGAYDGLPKVATWLRHRLTDLRARIGDPSGTADPRSSPHLLL
IFSTPELIGPQAPLAPHIHYVGPSLADRPAGPGFPWELLDRARAKVLVTLGTANADAGGR
FLVECRTALRERADRVQAVVADPGGALTVPPGDKDVLILPSVPQLALLERMDAVACHAGH
NTVCEALWHGVPLVVAPIRDDQPVVAAQVVDAGAGVRVRFGRVRADGLGAALDTVLTDPA
HRAAAARIRTAFRAAGGARAAAAHLERLAAECR
>A0A3R9RGH5|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus mitis|TrEMBL
MKRIKIDVVVLPLSGHLFPTLNLLAPLLKDPLYDIRLFTGPQRKAVAEEMGYQVFPILEN
SVDEFERVANNEGQLNLISAYRQLSASLDLIDVVSYQLVQEWQKNRPDIVIADFITLSGG
LVAEQLGIPWITTMATQFAIETTDGPPCFFGGMGSPKNPFQSTQQWLGRKVTRLGKRIVT
FLLRERLKRYDFKLYNQKNQETIYSPYSILGIGMKELELKSGFPEHYLWVGPFGSSIERA
ENYPLDLSPYAGYKKVLVSCGTQLAWAKDNLLYQTQQLAKAHPDCHFFVTLGFGGQGFQC
EKLMDNVSVVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIYGKPALILPHDYDQYDYAVRG
LEAGIALTAKREDTEAIGRAFDELLARDGWSDLNKLSRVAQDYQPTEILKNEIYRLLGDK
EK
>A0A5P9PT35|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Amycolatopsis sp. YIM 10|TrEMBL
MSRFLLVVPPLVGHVNPVVGVAAELARRGHEVAWAGHGELITRLAGAARVYDCALPPATA
RPPDLRGAAALKFLWEEGFLPLATAMAPAVEAAIADFRPDALLVDQQAVAGGLIADRLGL
PWLTSATTSAELTDPLASMPKVRDWVLDRLAGLRASIGDPAGTADPRFSPHGVLAFTTAE
LAGEMRGVHFVGPSITDRESEKDFPWDWLDHRPTVLVTLGTANADAGARFLAECAATGVR
AVVADPAGVLPSSDTVLSRPHVPQLELLPKMDAVVCHGGHNTVCESLWHDLPLVVAPIRD
DQPVIAEQVAEAGAGVRVRFTKATADHLRVAISTVLDPGSGMRANAARIGRSFRAAGGAA
AAAGHLEALTTAGVRA
>A0A3G4W771|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces sp. ADI95-16|TrEMBL
MKILLCPLSDGGYLYPSIAAGRELRRRGHDVSVLGRSTAAPVAADAGLPFAAAEDFGGHR
AFSATWWGPTGAAQYRATVRAARETGADLLVTSVLCNGALLAAETLDIPVAVIGLSVHLW
DYRAGGDDEPHLGRTRRSRTHDCLRLHADLREQAGLAGRASRWGDEPLLGDALLLRGDPE
LEYPGARLPERVHHVGPLSWEPAPDPAEVEAIGDHLSRSGKPVVYVHLGRFFEGRSLWPR
LNEAFTGGRFQAVVEQGRSTDPRPAPDADILLVRKRWMGPLVDRAGLVLSSGTSAPVLAA
LLRGRPLALSPNGSEQPLLAGACMRAGVAVHFPNNPSVEASPLLESAWRDDGLRSRAHVL
GSRLAAMDSAVRAADVVERVAGASTAPPAGAAPAGAAPAGAAPAGAPSATASVSSKENHE
YAISRPR
>A0A6J5CU99|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Burkholderia paludis|TrEMBL
MKRILFCVVPEKGHVNPCIGPAQHLRTAGCDVAFYAPADISAQLDGAGGFAFVGPREMPE
RHDLSRGASFAANIRDADWLRHWIRTLLIDLAPAQVDGIRAVLRDWRPDVVVIDPLLYAA
AIAAELEGLPWVSMSNSLNPVLPDDLDSELLRTVRWLVPERTRLFARYGLDARFRGCDIL
SPHLTLAFTTDALVGAPPPGVELVGPALPSGPRGDETPFPWERLDADRPLVYMSLGSQLY
YHPDVFAKVIDATRATSAQLVLSVGELVDSDLLPADDDRVVAVRYAPQLALLRRTQAFVS
HGGANSVMESLACGVPMLLSPFCNDQFHSAHFVERAGAGCVLDLQQAGVADIADALERLL
RPGSLREQAARIRASYAGDGSARAARLISALASGNRLATAS
>A0A1V5MAY0|4'-demethylrebeccamycin synthase|EC 4.3.3.5|bacterium ADurb.Bin425|TrEMBL
MKVLVLALGSDGDINPMVEIARAIKSRGHDVGFVANAYFADKVAAHGLDFIEMGDRASFE
AVTADPELWQPRRAFATVWKNLYKYLPGSVDALEKLVVPGKTVMVGTTLAIAGRILQEKA
ASAKLQAVPLSTVHLSPCCLISRFEPPTGPDFEIPSACPQIFKDIYFNLVDRFLLDGNCR
ADLNTYRRSLGLAPVKQVFSRWLHSPDQVLCAFPQWFAAPQADWPSPLRFVGFPLYNRSG
VESLSAATENFIAAGEAPLVFTAGSAMAHSHSYFALALEAVKKLNRRAIFVSRYKDCLPP
LPDFVHHAQYEPFDILFSRAAFVSHHGGIGTSAQALNAAVPQLVAPFAHDQFDNAFRLKK
LGVAQSVKADAFSESRAQDFTEKCRILLSAPYQEKAKEAARLMQDQSDAAARAALYVEEL
ERLL
>A0A2K8RGX5|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces sp. M56|TrEMBL
MSEPSRTREVPPRRFLFVVPPLVGHVNPTLGVAAELTARGHQVAWAGMPEVVQRLTGQGA
TVYRCAGPVLGEGGADRPPDVRGPAALKFLWERFLVPLAEAMAPGVAKAIGEFRPDVVIA
DQQTVAGGLVAERLGVRWATSATTSAEFTGALDGMPKIDAWLDGLMAEVRGRIGDPKGTA
DPRFSPDLVLAFTTEELAGRPARAGDRIHYVGPSIAERPATADFPWAWLDPARPAVLVTL
GTANTDAGARFLTECLEAVRARADRFQTVIVDPDGVLTRATPDVRNAPAAPDDKDVLVCR
YVPQLALLKRVNAVVCHAGHNTVCETLWHGVPLVVAPIRDDQPVVAAQVVDAGAGIRVRF
GRVRAAALGEALDAVLDEPRYRAAAERVSASFRTAGGATAAATHLERLATASAVTHVERP
ATGTAATHTTTNPGGER
>A0A8F8Y351|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Nonomuraea coxensis DSM 45129|TrEMBL
MTPGGPLTRVLLVAHGSDGDVLPFVRLGGVLRERGHDVTLLTHAPYRERVEAAGLDFVPV
DTHDAFARYSADTALLPDGLGTLDWLSFYRRNHLFEQFAGECRALVARVVPGRTVLAGRH
TSALSVLAARELTGAPAAWIAVAPIQPLAAEVARHLHQHVLGPGIDAVRGDLGLPRVPDW
RAWFSSADLRLGLWPRWFDAAGPATGPAMRLTGFPLPDDDSADPVPAEAAELLDGTVRPV
LITGGTGRMLRPGFHDAALAGCRRAGLPALLVAPHAESVPRPLPPHVRRFARLPFREVVP
QVAAVLHHGGIGTLTRALAAGTPQVILAHGADRPDNAARLEKQGLARWLPEERWDAGEVA
EALRAALRDGRHPPRTGPRDAADGLALAATHLERLLHGPARLGEPLTEEEQGGEARRRLA
ALPAERRRLVAARLRRPAGQEAS
>A0A428CLK4|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus mitis|TrEMBL
MLERTIILVVLFLKICYPRHMRKIKIDVVVVPLSGHLFPTLNLLAPLLKDPLYEIRLFTG
PQRKAVAEEMGFQVLPILENSVDEFERVANNEGQLNLISAYRQLSASLDLINVVSDQLVQ
EWQKNRPDIVIADFITISGGLVAEELGIPWITTMATQFAIETTDGPPCFFGGMGSPKNPF
QSIQQWLGRKVTRLGKRIVTFLLRERLKRYDFELYNHKNQETIYSPYSILGIGMKELELK
SGFPEHYLWVGPFGSSIERAENYPLDLAPYANHKKVLVSCGTQLAWAKDNLLYQTQQLAK
AHPDCHFFVTLGFGGQDFQCEELMDNVSVVSYLPYKEYIPQMDYVVHHGGAGIFYQCIIY
GKPALILPHDYDQYDYAVRGLEAGIALTAKREDTEAIGRAFDELLARADWSDLNKLSRAA
QDYQPTEILKSEIHRLLEDKEK
>A0A428DHU3|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus mitis|TrEMBL
MLERTIILVVLFLKICYSRHMRKIKIDVVVVPLSGHLFPTLNLLAPLLKDPLYEIRLFTG
PQRKVVAEEMGFQVIPILENCVDEFERVANNEGQLNLISAYRQLSASLDLINVVSDQLVQ
EWQQNRPDIVIADFITLSGGLVAEQLGIPWITTMATQFAIETTDGPPCFFGGMGSPKTSF
QSAQQWLGRKGTRLGKRIVTFLLRERLKRYDFKLYNRKGQETIYSPYSILGIGMKELELK
SGFPEHYLWVGPFGSSIERAENYPFDLSPYAGYKKVLVSCGTQLAWAKDNLLYQTQQLAE
AHPDCHFFVTLGFGGQDFRCEELMDNVSVVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIY
GKPALILPHDYDQYDYAVRGLEAGIALTAKREDTEAIGRAFDELLARDDWADLNRLSRVA
QIYQPTEILKSEIHRLLGDKEK
>A0A1B8YGB2|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Photorhabdus namnaonensis|TrEMBL
MARIVIAAVATPGHVYPMLKVAQSLIAQGHQVTVFTGALFRQQVEALSAQFVPFDEQIDF
DYRHLEQHFPDRAQLPPGNVQMALAFKNFFSAPIPVLDRQLRQIIREQQADLLIAENCFY
GILPLLQEEKTHRIPMIVIGITPLAYSSKDSIFWGPRIPPAVLPPELTHEQLVDETNQQL
IAEVQDSFNDALVQSGSSALTRPFNDEVILSADRFLQLSTLAFEYPREGLPDTVHFIGPL
PNPAPTTTSPQLWEEDDPRPLVIVTQGTISNTDLNQLILPTLRALATLPIRILATTGGRS
VETLSKDLPENVRIEEFISFEHWLPKASLLISNGGYGTINYALSHGTPLLIADAGEGKQE
AAFRVVWAGCGTNLDTAHPTESQLKQTVENMLSTDLFKQRAQIVQKDYARHDALAAISRH
IEQLIHLFLT
>A0A1E3H1K8|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Methylobrevis pamukkalensis|TrEMBL
MPRSSYLFATHGSLGDLNPFLALGSFLRQGGSRVVIATHETYRARVEALDLEFVSIFPDA
GGYEAELGMDAAAIVHRVSDDFDFFLRDIVGRHVEASIERLLPVVRTVDMVIASSYAHGA
HIAAQMEGKRFVGVALQPAAMVAAGEPAVIARMPMMQTPSRRLDRLFNRAILAIANWRMR
GALATVRQAYTIRGLKPEAGINGITADVPTLALFSPLLGGTPAQADGRSRMTGFLYLDDE
VVSGEVERRVSTFLAAGPAPIVVTLGSFNVTVGERFFRMAIRATRRLGHRCIVIAGEASP
LLGEDFGRQVLVLPYLPYARIFPHAAAIVHHGGIGTCAQALKAGRPQVVCPLFADQHDNA
HRITRLGAGETLEFRRARPRRTQAALKRILESPEIDERCRSLAETIGREEGLLAAAAFLR
NSVDEALPAEAVVYARAQA
>A0A5C6B7R5|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Stieleria varia|TrEMBL
MRILILTVGTRGDVQPYLALALGLQDAGHDVRICTCQIFESWIASRGVGYLPLNNDIRDF
MESDDGRLAMETTTNLLAAIRTGVRLMPKLKGMMHRQIDEMWAAAESFQPDLILFHKKAI
GAEDFAEKLGCRCALAFYLPMYVPTSESPAFGFPRLPLGGLYNRLTYRAVEIVTRLSARK
FVKRWRESHGMPANRPPFFQHADGTPISSLQAYSPSVVPQPSDWPDHALVTGYWFLDSES
NYQPSQPLVDFIEQGPPPIYVGFGSIFGRDPRATTQRVIEGVRQSGCRAILASGWGGLDL
RDLDLPESMLAIETAPHDWLFERVAAVVHHGGCGTTAAGLRAGRPTIICPFFGDQPFWGR
IVHGLGVGPKPIPQRKLTAEKLAAAIRSTLSDSTMRSKAAELGMRIRSENGVSNAVNFIQ
QIPRPT
>A0A3N6CL47|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces sp. ADI91-18|TrEMBL
MKILLCPLSDGGYLYPAIAAGRELRRRGHDVSVLGRSTAAPVAAGAGLPFAAAEDFGGHR
AFSATWWGPTGAAQYRAVVRAARETGADLLVTSVLCNGALLAAEALDIPVAVVGLSVHLW
DYRSGGDDEPHLGRTRQSRTHDCLRLHADLREQAGLAGRASRWGDEPLLGDALLLRGDPE
LEYPGARLPERVHHVGPLSWEPAADPAEVEAIGDHLSRSGKPVVYVHLGRFFEGRSLWPR
LNEAFTGGRFQAVVEQGRSTDPRPAPDADILLVRKRWMGPLVDRAGLVLSSGTSAPVLAA
LLRGRPLALSPNGSEQPLLAGACMRAGVAVHFPNNPSVEASPLLESAWRDDGLRARAHVL
GGRLAATDDAVRAADVVERVAGASAAPPAKASVSSKENHEYAISRPR
>A0A5P9PFE9|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Amycolatopsis sp. YIM 10|TrEMBL
MDALLLTYGSQGDVQPFIALAGALRAAGHGVRLAGPARSAKLAGDLDYRPITDALIEAVD
TDEVRQARDSGKGAGAVARSLGAVKAAAREALDDSWSAAADGADVIVHHPITAGHHLAEK
LGVPSVPASLFPTNVPTSEFPCATAPVRLPKALNRLTYRLDGLAGLALRGTVDDWRGSLG
LPKRRGRHDFLRDPRGGHVTVLNAFSRHVVPPPADWPVSVHTTGYWFLPTDPEWTPPAEL
TAFLDAGEPPVCVTFGSLVGSDPAKTARTVLAAIRAAGVRAVLIAGWGGLRVDEVPDDVL
VVDQVPYDWLFPRAAAVVSHSGAGTSSAAAAAGRPQVGIPMDVEQPMWAARLHGLGVGPA
PIPYGELAEAPLAAALRAVTTEPAYASRAAELGELINAEGGAAEAVAVLERRMD
>A0A0H4VUY5|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Bordetella hinzii|TrEMBL
MKIVVLTYGTEGDTRPLIALSHALIQAGHETILLGEARSLGSARRLSVPVRPLSGDIRTL
FTRWGQSGARGTAKALVDLTNAQSAAWMAQTLETAQGCDAILVSGLAGFVGLSVAERLAI
PAIGAGMIPLTPSNEFPSPFLAPAWVPAPLNRASLRLTNQLLWLGLRKALNRARADVLGL
PPRDRLWTTHPMLYGISPTLLPPPRDWPDNAVLCGQWTPPPDSGFIPPAELTQFLDAGPA
PIYVGFGSMTGIDLPRMLQTVIQALDGRRAVVWPGWSDMGTMTLPPNILRIDATPHDWLF
PKMAAIIHHGGSGTSHTAASAGRPSIILPFAGDQAFWADRLHRLGVAAPAVSPQRLHAKA
LAQAIAFVEQPAVNARAAQLGQAMARENGLAVAVERMEKWLATRAAR
>A0A4R8S842|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycobacteroides salmoniphilum|TrEMBL
MRVAVVAGPDPGHAFPAIALCLKFAAAGHDPVLLTGTRWLDQARSAGVESAELLGLQPRA
GDDDLDSGTKIHQRAAYMAAANVDQLRELSPDLIVSDVITACGGMAAELLGVPWVELNPH
PLYLPSKALPPLGSGLAPGVGLRGRLRDVLMRKLTQKSINEGLSQRSQARVGIGLSAKDP
GPVRRLIATLPALEVPRPDWPDEAVLVGPLHWEPTDVVLQPPSGSGPVVVIAPSTAFTGA
EGMTELALQALESAGARVVVSALDPAASGLPPWAVAGLARQDLLLAGADLAICGGGHGFL
SKALLAGVPVVVVPGGGDQWELANRAVRQGSAELVRPLSRDSLTGAVGRILGERRYVEAA
RRAAAGAVDVEDPVRVCQDALAALK
>A0A7G2JJ46|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Serratia grimesii|TrEMBL
MACILMTAVATPGHVYPMLSIARHLIAQGHQVRVMTGALFRERAEAAGAQFIAFDERVDF
DYRYLEQHFPERAALPPGNAQMALALKDFFAAPIPLLDQQLRIAIAAEPTDLLMVENCFY
GVLPLLQTMDRPPVLGIGVTPLSYSSTDSIFYGPRIPPALLPRDLLREQLVDDETRLLID
EVQQRFDFAMAQSGGKPLQQAFTDALIGGCDRFLQLATPALEYPRDDLPDSVRFIGPLRH
VATAEQTPDLWDESDRRPLVIVSQGTLANVDLHQLIVPTLKALSQLPVRVLATTGGRSVE
ALLALLPANAKVQEFISFDHWLPQAALLITNGGYGSINAALDHGVPLIVAGTGEDKLEAA
TRVVAAGCGVNLQTSNPDEAQLRQAVRQILAQPLYRQRAALVQADYARHDALAMIAEEVV
ALTG
>A0A1Y5RVR5|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Pseudoruegeria aquimaris|TrEMBL
MRQGKPYHVLLATIGSAGDVFPYMEIGRVLKAQGHRVTLMTTPLLAEMVADHGLDFAPFG
DLDQLKSAAKDPKIHGEASGPGAFWDRLVAPNLLAIRRFVEALPKEEHPVVLCHTFLVPA
AALARSAGRPITIINPILQPAFIRSALTRQTFGVPKLGPVTFGRWMPAALRRLITRKGED
RMINAPMLPALNALRHETGLPPVESFFGHIQEAADLYVPLFPTWFAAPQADWPAPRVQGD
FIFYQALKSQAVSPELQGFLDSGPAPVVFTAGTGNFQANRLYSIAIPVLKRLGLRAVFLT
HVRDQLPDPLPEGMLWQPYAPFDKILPSACALVQHGGIGTTAEALRAGVPQLVTPFGYDQ
YDNARRIREMGAGTSVPFQHLTEEKFEKALSGLLATNRRRPTFAGSMATEEIVAAIFEAI
GPASRS
>A0A3R9SDB7|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus oralis subsp. dentisani|TrEMBL
MLERTIILVVLFLKICYSRHMRKIKIDVVVVPLSGHLFPTLNLLAPLLKDPLYEIRLFTG
PQRKVVAEEMGFQVIPILENCVDEFERVANNEGQLNLISAYRQLSASLDLINVVSDQLVQ
EWQQNRPDIVIADFITLSGGLVAEQLGIPWITTMATQFAIETTDGPPCFFGGMGSPKTSF
QSGLQWTGRKGTRLGKRIVSFLLRERLKRYDFKPYNQKGQETIYSPYSILGIGMKELELK
SGFPEHYLWVGPFGSSIERAENYPLDLSPYAGYKKVLVSCGTQLAWAKDNLLYQTQQLAE
AHPDCHFFVTLGFGEQDFQCEELMDNVSVVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIY
GKPALILPHDYDQYDYAVRGLEAGIALTAKREDTEAIGRAFDELLARDDWSDLNKLSRAA
QIYHPTEILKSEIHRLLGDKEK
>A0A1Y2N1Y1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Pseudonocardia autotrophica|TrEMBL
MTDYLFALTDGGGTVPPELGVAHRLVTRGHRVRVLADASMAADVAAIDAEFLPWAPGRDD
PAPASAYRDWELRSPWALAGGMAEHMIAGPAAGHTHRLLEVVRTGAPDLGLAPVPGVWDQ
VHRARRQLVLTARTFDFPARLAPSVRYVGPVLDDPSWAHGERWEPPAGDGPLVLVAMSST
YQAQYATVRNVVDALTRSGARGLVTVGPALDPGLVRGGDGIVVVRSAPHAEVLDHVELVI
THGGHGTVLKSLVAGRPMLVLPHGRDQRDNAARVTFRGAGEMLRRSATADRIAAAANRVL
HTPYYTAAARWFGGRIRAELARSTLLAELEQRPA
>A0A6J4GLM2|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Flavobacterium bizetiae|TrEMBL
MSKVLFLSIPSHGHMNPMMGLANELVNQGEEVLFFSSEEFKKPIQELGAEFKCYKEDLNI
FQKKEEKPVEDASKKKSLTGLASALLHPEVFIDAILEEIQGLQFDYIVFSAAYPYAKLIS
QILQIPSVSSYAVFATKEDLFNKKASPGNEPPKKGPFGLSPEIMKEFQTVRENLIEKYKI
KLPENMMDLFFNKGDLNIVYTSKYFIKNINNYDESFLFIGPPIYNKKYNVDFPFDKIEGK
KVVYISLGTIFSNHSKDLNNLFFDAFANTDYVVVMAAHKVNLDQYKIPANFIIRDYVPQL
EILKHTNVAITHAGMNSMGDLVYNKVPFVSIPLGADQFFLANRAEELGATIVLDVNTLTS
ESIKNTVEKVNTESSYAENIAKISNSFIEAGGYKKAVEEIFRLKSK
>A0A5C6CFB1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Bythopirellula polymerisocia|TrEMBL
MKFLITALGSYGDVFPMVGLGAALCGRGHQVVLVTNPHFQAIVEAAGIEFLPLGTAEEYD
ELAHHPDLWHPMRGPIMVLRKSFKNGLRELYDIVSANVTQGETILVAHCLDLASRIHHDK
FGTPLASVHFAPVALRSFHQSPQMFGMLMQSWVPSTLRKFQFWLADKMVDHLVAGEVNAL
RGKLGLPPVRRVMHEWYFSPQLVLGMFPAWFAPPQPDWPPQTRLTGFPLWDQSVQENLQP
DVEEFLQSGSPPIVFAPGSAMTRGEKIFAAAVDACQRLDRRGILLTRYPEQLPATLPESI
KHCHFVPMSRLLPRCAALVQHGGIGTSAQGLAAGLPQIVMPMAYDQLDNATRLKNLDVAE
ILRPKRFTGANLAAGLDRLLGNSYVTKQCQHWAQQFDLPAAMNASCTELESLGGA
>A0A165W401|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Pseudovibrio sp. Ad26|TrEMBL
MLQPAKILILTYGSRGDVEPFIALACGLTARGHTVTLSSAEKYWDWVKSFGLAFEPLSND
TIDLMTTPDGIAALEGSSGLIKRVAAGTRLAKKSGRLNDGLNRDAWRAAQAVQPDLIIFH
PKVMAAPHIAEALDIPAVMGLLQPMIVPTNEFPVAGMPRLPIPGYNKLGYALVKLSYSAF
RKSVNQLRTKALKLTAIQHRNEVLFPRGALPIKTLHAISSWVVPRPKDWPDAAVMSGYWS
LKSDGDYEPPASLRSFLERGPPPVYIGFGSMTVEDPKALQEVLVEALRKANVRGVLSTGW
AGFDAIESDDILSVSDVPHEWLFPKMAAVVHHGGMGTTAQGFRAGVPCVLCPFFGDQPYW
AQKSVALGVGAPPVPRKALTADKLAHSIHLAVNDASLKKNASDLALHLQSEDGVGTAVAE
IEACLAGVSSK
>A0A518IYC0|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Rosistilla oblonga|TrEMBL
MPTANSNQPLAIVSAFGSRGDVNPMLALARELHRRGWRILFLTSAPYQALAEAAGFDSQS
LVSQEEFDAFITKPGLWQPIQGLRVVLGETATMLLEPTFELLRDRVEPGNTILVTHPLDF
ASRIYRDLHPDLPLIGTVLAPMAIRTPRDPAKLTGWPIEISRPAWLVEASYHAADWLFIR
KWLGRPVNRFRKQQGLPPIDRVLKSWYLSPDLVLGLFPDWFAPRPDQRPPQLQCTGFPLE
DAAGEMAAENIAAVQAIRDQHGQPPVVFAPGTANRQAADYFQIATDVCQALEIPAILQTE
FPQQLPKRLPPNVVHKSYLPFRALLPHCRAIVHHGGIGTTSQSLAAGTPQLVVPMAFDQF
DNARRVERLGCGKSLLQRKLSQRRLTQQLADLLADDTTRPRCHELRDRMKTNDTVGQSVD
AIERLAIAKGVLPHPTGDN
>A0A0J1F944|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Peptococcaceae bacterium CEB3|TrEMBL
MKVICTAQMGGTALGQTMRVVAVAKELKRRGHQVKILAGEKQIPLMQSQGLDFIPMPPLA
ADFPFGAMWGAPGKAREEVMARLKQIIEPLAKAEQEIVRREKPEVMVCGSFTGPSSARAC
DIPCALVVLQPHGRKTMEFATQRMQGGTRFWEMLKAVSLIIMEGMPELDGGMAAEIKGEW
AEALREKIRFTGPLLAEPPENLSAREDLKFRYAGDKEGALVYVTIGGGTPLIGKDFLSLV
LEAFRPLPDVHVVMATGLALEPGELAEYDPPSNVSVHGFVPGLELIKASDVTVFHGGSST
LMTCLACGTPAVVVPSMVEQEDNGAVLEANGAGIVLAKNDLTPTALAEAVRKILQEPAFR
RNAEKLRQLGEKYGGASAAADMVEQMSKQE
>A0A7J5X3K2|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Gordonia sp. YY1|TrEMBL
MHVALVAGSDAGHAFPAFALAERFTAAGHRATVHTGLNWSAAARRRGIDIAELPGLAATD
VDDDADAGDKLSGRAARMADLLAPLLAESGADLVVSDVITVCGGWAAQLRGLPWIELSPH
PLYMPSRGLPPIGSGLAPGTGIRGRVRDTLMRAATATSIRKGERQRAAARLSIGLPALHG
GPCARFVATLPGLEVPRPDWPADTHLIGPLLWEPTDDLFDRPDGDAPLVVLAPSTAQTGA
PDMVGVVLEALSERVLGRRVRVVVSGLHRPSTADLARFGDSSAPIAAGLGRQDEVVADAQ
VLICGSGHGILAKAMSAGVPVVAVPGGGDQWELANRLRRAGAGRLVRPLTVEAAADAVRT
VLDDPEYARSARRIGASGADTVDPVAVAHAVLDRASFRRVGPCA
>A0A5S9RA59|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycolicibacterium vanbaalenii|TrEMBL
MPEILVATLSSAGRAEPLFSVAGDLVGRGHRVTVMTGVAHAESVRQLGARLHPLPATADG
EPSSHTAGAGPDDFSRRLPCQTVEFRRALGERRYDVVIMDYGLSGIVPLLSGAATAVPPV
LCYTPTPAVPAQLLEVGALFDRLIVPTVPSFEYPHNDLPASLRFVGVVRPRPPDGFVPPA
WWAELDGARPVVHVTQGTDNGDLSQLVEPCISALADSDVTVVVSTGGRDPGALGIPLPAN
AFVAEHLPQDLLLPKVDVLVTDGGYATVQPALAAGVPIVVAGSTGDRAEVAARVAWSGTG
INLQTGTPSPAAIAAAVQRIRSEAGFLRNARRLEADFARRDGVAEIAALVDEVVGERAQR
WAN
>A0A3R9L723|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus mitis|TrEMBL
MKRIKIDVVVLPLSGHLFPALNLLAPLLKDPLYDIRLFTGPQRKAVAEEMGFQVLPILEN
FVDEFERVANNEGRLNLISAYRQLSASLDLINVVSDQLIQEWEKNRPDIVIADFITLSGG
LVAEQLGIPWITTMATQFAIETTDGPPCFFGGMGSPKNPFQFAQQWLGRKGTRLGKRIVT
FLLRERLKRYDFKLYNQKNQETIYSPYSILGIGMKELELKSGFPEHYLWVGPFGSSIERA
ESYPLDLSPYASYKKVLVSCGTQLAWAKDNLLYQTQQLAKAHPDCYFFVTLGFGGQDFQC
EELMDNVSVVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIYGKPALILPHDYDQYDYAVRG
LEAGIALTAKREDTEAIGRAFDELLARDGWSDLNKLSRVAQDYQPTEILKNEIYRLLGG
>A0A143QBP6|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Rhodococcus sp. PBTS 1|TrEMBL
MRHRTGRSAHLRNRLAHAAVRHLLFRRTQQLAARLVADAGGSLDTFVLDYSTLCDRFLQM
GPSEFEYARSDLAPNTVFAGPVPSRPGPPTPPPGWWDDMVADPRPLIHVTQGTLDNHDLS
QLIEPTLHALADADVQVVVSTGGAPVDTIAQSLPNNARAASYLDYDALLPRTAVMITNGG
YGGVLTALRHGVPVVVAPGAEDKPEVAARVHHVGVGIDLRTRRPTPSAIRTAVDTALTSP
DIRRAATGLQHAIATYTPLETVRTELAATLTDHAARTDWSPT
>A0A165QRL1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Pseudovibrio sp. W74|TrEMBL
MLQPAKILILTYGSRGDVEPFIALACGLTARGHTVKLSSAEKYGDWIESFGLAFEPLSND
TIDLMTTPDGIAALEGSSGLLKRVAAGTRLAKKSGRLNDGLNRDAWQAAQAVQPDLIVFH
PKVMAAPHIAEALNIPAVMGLLQPMIVPTNEFPVAGMPRLPIPGYNKLGYALVKLSYSAF
RKSINQLRTKALKLPAIRHRNEVLFPRGVLPIKTLHAISSWVVPRPKDWPDVAVMSGYWS
LKSDGDYEPPASLRSFLERGPPPVYIGFGSMTVEDPKALQEVLDKALRKANVRGVLSTGW
AGFDAIESDDILSVSDVPHEWLFPKMAAVVHHGGMGTTAQGFRAGVPCVLCPFFGDQPYW
AQKSVALGVGAPPVPRKALTADKLASSILLAVNDAVLKKNAHDLALHLQSEDGVGIAVAE
IEACLAGVGGT
>A0A5B9W2M8|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Aquisphaera giovannonii|TrEMBL
MNHDSSPAGPSARRIVLMAVGSYGDVHPYIAIALGLKARGHNAVVATCACYRKKVESLGL
GYRTVRPDCDRVDDPSFMTRYMDPRRGTFRVLRELFLPALRDSYEDAMAAAEGADLLVSH
TIFYATRLVAATTGIPWVSTAITPSALYSAYDPPLFPGRPAISRLLRPLGPRFWKGAWSL
AGRATRHWAEPIRRLEAELGVTPVKHHPLVDAHSPGLVLALFSGVLAAKQPDWPPQVAVT
GFPFYDRRDGEDPGLPAELARFLDDGPPPIVFTLGMSSANVAGRFFEDSLAAAGSIGMRA
VLLGKRHGHVEPADPAKAIWCEYAPFSLLFPRAAMVVHGGGIGTTGLSMRAGRPMLVVPF
SHDQPDNADRLRRLGVARVLPGPRYDARRAAAALRMLRDDPSYARRAAEVGERVGREDGV
AAACDAIEGLLRPGRDGNGAGPPRRGCP
>A0A0M2H3S5|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Microbacterium ketosireducens|TrEMBL
MSDILFAAVPIHGHVAPLLPLVRHFVDRGDRVRFLTGSRFADAVLRAGAEHVPLPAAVDF
DDRGVTAAFPERAAMSPAKAIAFDFEHIFVRPGEHQHAALRDLIDAGDVDAVVCDPLFVG
AALLVESDPKQRVPVVVAGVVPLSYPGPGLAPFGLGLAPLGGAVGRIRNGILRMATQRMF
RPVEAAADEIAVRALGAALSGPVLDWLPRADAVCQLTVPRFEYPRPDAPASLVFTGPVGA
AAPAAAHPSWWGDLTGERPVVHVTQGTIANDDPNELILPTIRALAGADVLVVVSTGGTPV
EELGPLPSNVRAAEFLPYADLFPKTDVFVTNGGYGGTQFALAHGVPLVVAPGKEDKVEVA
ARIAWSGTGVNLKTQRPTARQIEKAVRMVLADPRYRTAAREIGADIRAASHAVGFASVVD
ASIAAHRAPRATAPRPE
>A0A428IG30|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus oralis|TrEMBL
MRKIKIDVVVVPLSGHLFPTLNLLAPLLKDPLYEIRLFTGPQRKTVAEEMGFRVIPILEN
CVDEFERVANNEGQLNLFSAYRQLSASLDLINVVSDQLVQEWQENRPDIVIADFITLSGG
LVAEQLNIPWITTMATQFAIETTDGPPCFFGGMGSPKTSFQSGLQWLGRKGTRLGKRIVS
FLLRERLKRYDFKLYNQKGQETIYSPYSILGIGMKELELKSDFPEHYLWVGPFGSSIERA
ENYPLDLSPYAGYKKVLVSCGTQLAWAKDNLLYQTQQLAEAHPDCHFFVTLGFGGQDFQC
EELMDNVSVVSYLPYKEYISQMDYVIHHGGAGIFYQCIIYGKPALILPHDYDQYDYAVRG
LEAGIALTAKREDTEAIGRAFDELLARDDWPDLNKLSRAAQIYQPTEILKSEIHRLLGDK
EK
>A0A679K1K3|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Methylobacterium bullatum|TrEMBL
MRVLIAATALTGHITPLLAAGRLLAARGDSVVMTTAEEFRDKIESAGLRFAPIDDGHAAE
YRETSLPAGPERYRREFARRFIDPIPVQFEALSRLVEAERPDVIVAGSLFLGVLPLLLGS
RPRPPIVVLNVSFLFLDRPDDAPVGLGLPPARTETEHAHYALLKAGMDAAFVDPVRAYAD
AQMALLGLPPLPASLPHSIAILPDLFLQPTVPEFEYDYGTLPPNLRFTGLLPVPPTHAPL
PDWWRARDVTKRVVLVTQGTLANADFGELIEPTLAALADRDDLLVVATTGGRPVEALSGP
LPGNARVAPFLPFDAMLPDISLLVTNGGYGSVSQALADGVPIVSAGLTEDKAEIGGRIGW
SGAGFNLATNNPTARALREAIDTVLGQPHFRARAASLARAFAGLDSGRAVLAGIDDVVRG
GPIVRGIAA
>A0A517XXT0|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Urbifossiella limnaea|TrEMBL
MRLLVSTFGSAGDVFPMLGLALALRGRGHVVTFATNPYFEEPVRRHGFDFEPLGTAAQFE
DTIRDPGLWKPRTGFRTVLDRLGDAIRQQYTLHEKLRLPGVTNVFGFGALTAREKLGLPV
VSVHLQPSVIWSNVVPPDFAGLAGPLWLRRLLYAAGIRFFAHPTVARSLNPWRAELGLGP
LPRVDRWWHSPDGVVGLFPDWFGPPQPDWPPGVVLTDFPLWNDGTADGLPADLAAFLDAG
EPPLAFTPGSANVHGRAFFAAAVDAAQRLGRRALLLTRFPEQLPAALPPGVRHVTYAPLD
VLLPRTAAFVHHGGVGSMSQALAAGTPQLVMPLAHDQFDNLARAVRLGVGEGLAVKRFTG
RRVAAALARLLGSAEVASACRAVAAKLTVRDGLARSAAAVERLITARNPG
>A0A3N6H9F8|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces sp. ADI97-07|TrEMBL
MKILLCPLSDGGYLYPVIAAGHELRRRGHHVGVLGRATAAPVVAGARLPFMTAEDYGGRR
AFSAARWGTTGRAQYEATVRAAREAGADLLVTSVLCNGVLLAAEVLDIPVVVVGLSVHLW
DYRSGGEGEPQLGRTRASRTSEGLRLYTELREQAGLAARASRWEAGPLLGDALLLRGDPA
LEYPDAELPERVSHVGPLAWEPTPDPGEVEAVREQLDRTGKPVVYVHLGRFFGGGSLWPR
LNAAFTGGRFQAVVEQGRSTDPQPAPDADVLLVRKPWMGPFIDMAGLVLTNCTSAPVLAA
LLRGRALAVSPNGAEQPLLAGACLRAGVAARMPDTPAARPSALLESAWEDQGLRARARVL
GGRLAAMESAARAADIVERTAQASATPKKEEDHGYAISRP
>A0A3R9KMX0|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus mitis|TrEMBL
MKRIKIDVVVLPLSGHLFPALNLLAPLLKDPLYDIRLFTGPQRKAVAEEMGFQVLPILEN
FVDEFERVANNEGQLNLISAYRQLSASLDLINVVSDQLIQEWEKNRPDIVIADFITLSGG
LVAEQLGIPWITTMATQFAIETTDGPPCFFGGMGSPKNPFQFAQQWLGRKGTRLGKRIAT
FLLRERLKRYDFKLYNQKNQETIYSPYSILGIGMKELELKSGFPEHYLWVGPFGSSIERA
ENYPLDLSPYASYKKVLVSCGTQLAWAKDNLLYQTQQLAKAHPDCYFFVTLGFGGQDFQC
EELMDNVSVVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIYGKPALILPHDYDQYDYAVRG
LEAGIALTAKREDTEAIGRAFDELLARDGWSDLNKLSRVAQDYQPTEILKNEIYRLLGG
>A0A517T3P6|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Calycomorphotria hydatis|TrEMBL
MHILLLPFGSFGDVNPYVGLGMALKERGHRVTVGTVGYFRDVVEKEGLEFFEIGTAEEYQ
QVIGHPHIWHPIWSFGHIFRTGISKVLQKQYDFIAEYYQPGETVVVTSSMGFGALCAREK
LGVPLVTVHLQPSVMWSEFASPVLAGMPTNMPRWWKRFQFACGEWLAIDRACCPQLNRFR
AELGLPPVNHLPRWWHSPDQVLCLFPEWFGPTQPDWPQPLAHAGFPLWDSDSEQQPLREF
VQFIDEHPRPLVFTPGSANQHAEKFFRTAIETCRLMDSPGILLTRYPEQLPPELPPFVKH
FKYLPLERVLPHASALIHHGGIGTTAQALKAGIPQVIMPLAHDQFDNAARLKKLGVGDSL
SPTFFSAPRLTRVVQRLLTSEQSRAACKALAEKVREGDCFEKACEVIASAGSRQVVHQ
>A0A1Q2ZDY4|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces acidiscabies|TrEMBL
MSGFLFVVPPLTGHVNPAVGVAARLAARGHRVAWVCPDRELVRRLAGADAVVFGCGDELS
RITHAQAASHRPADVRGPEALKFLWERFLLPLAEAMAPGVRRAVEVFRPDVVVADQQAFA
GALVAERAGIPWATSATTTAEFTDPLAGLPKVREWIDARLGELRRTVGNASEGADPRFSP
HLVIGFSAPELAGDVEGVRWVGPSVTGRPDAGGFPWEWLDPDRATVLVSLGTANADAGER
FLAVCRDVARERAGRLRAVVVDPGGVLGAGTDDNVLIVPSVPQIALLAKGVDAVVCHAGH
NTVCEALWYGVPLVVAPIRDDQPVIAGQVVAAGAGVRVRFGRVGAQQLGAALDAVLDEPS
YRARAARVGAAFRAAGGADAAAVHLEELAERSRA
>A0A3R9TQR7|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus oralis|TrEMBL
MLGRTIILVVLFLKICYPRHMRKIKIDVVVVPLSGHLFPTLNLLAPLLKDPLYEIRLFTG
PQRKAVAEEMGFQVIPILENSVDEFERVANNEGQLNLISAYRQLSASLDLIDVVSDQLVQ
EWQENRPDIVIADFITLSGGLVAEQLGIPWITTMATQFAIETTDGPPCFFGGMGSPKTPF
QSVQQWLGRKVTRLGKRIVTFLLRERLKRYDFKFYNQKGQETIYSPYSILGIGMKELELK
SGFPEHYLWVGPFGSSIERAENYPLDLAPYANHKKVLVSCGTQLAWAKDNLLYQTQQLAK
AHPDCHFFVTLGFGGQDFQCEEIMDNVSVASYLPYKEYISQMDYVIHHGGAGIFYQCIIY
GKPALILPHDYDQYDYAVRGLEAGIALTAKREDTEAIGRAFDELLAGDDWPDLNKLSRAA
QVYQPTEILKSEIHRLLGDKEK
>A0A3R9J643|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus oralis|TrEMBL
MRKIKIDVVVVPLSGHLFPTLNLLAPLLKDPLYEIRLFTGPQRKTVAEEMGFRVIPILEN
CVDEFERVANNEGQLNLFSAYRQLSASLDLINVVSDQLVQEWQENRPDIVIADFITLSGG
LVAEQLNIPWITTMATQFAIETTDGPPCFFGGMGSPKTSFQSGLQWLGRKGTRLGKRIVS
FLLRERLKRYDFKLYNQKGQETIYSPYSILGIGMKELELKSGFPEHYLWVGPFGSSIERA
ENYPLDLSPYAGYKKVLVSCGTQLAWAKDNLLYQTQQLAEAHPDCHFFVTLGFGGQDFQC
EELMDNVSVVSYLPYKEYISQMDYVIHHGGAGIFYQCIIYGKPALILPHDYDQYDYAVRG
LEAGIALTAKREDTEAIGRAFDELLARDDWPDLNKLSRAAQIYQPTEILKSEIHRLLGDK
EK
>A0A0J6YGJ0|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycolicibacterium chlorophenolicum|TrEMBL
MASIVIGSVPVHGHVTPLLTVAAQFVARGDDVRFVTGSRFADKVAATGARFVPLPAEADY
DERNLTGSFPQRARLKGARAIAFDIEHVFARPARAQYGALVAALAEQPADAVLADPAFVG
AAFLLHHRRPERPAVVQCGVLPLCIESRDTAPFGMGLAPARVLNRPRNAALARVNRRVLR
RPYALIDDLHRAQHGVDMPDTLVDWGRRADALVQFTVPAFEYPMSDAPEALHFAGPLSAT
GSQAPLPEWWSDLDGRRPVVHVTQGTFANLDYEQLIVPTLRALADQDVVVAVTTGGRPLD
TLPDLPPNARAATYLPYDELLPRTSVFVTNGGYGGVQYALRFGVPIVATGGKEDKPEVGA
RVAWSGVGRRIRSEYPSARVLRREILAVLRDSRYRQASERLAAQMAATPGFTGLAGVIDG
LTERPTRTCANP
>A0A0J6WM41|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycolicibacterium chubuense|TrEMBL
MATILAYTSPALGHLLPLSALLAELMARGHQIHIRTLADGVETAVAQGFSAASIDPRIEA
IEMDDWRAANPVSALRLSVSAFRRRAPYEVGDLRAAIAEVAPDGLLVDVNCWGAQTAADA
ADLPWASFSPYTPALDVEGVPPFGLGLRPVRGIVGRWRDAVVRAAVNRPLQRPAVAAINA
IRAPLGVRPVASLDDFLRRPPLLFLATGTPFQYTADWGSNVHMIGPCVPEPVAGEPPEWL
SSIDRPIVLVTTSSERQNDADLVSAAAAALTDDPVHVVATLPAGVTEGLVDRPRVTVRRF
VDHDQVLARAVCAVTHGGMGGTQRALARGVPVCVVPYGRDQFEVARRAEVAGCGTRLPAR
RLSVPRLRRKIHEAMTMGPGAARVAQGFRATGGVARGADLFEELMER
>A0A1Y2NY40|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces fradiae ATCC 10745 = DSM 40063|TrEMBL
MTRVLIATTPAPGHVVGVLEVARELTRRGHEVRWYTGRAFQERVEQTGARFEPMREELDF
GGRSREEAYPHHAGLTGIAGFKAGVRDIFYRTAPGQMEDLLAVLERFPADCVLADDMCYG
ACFAAERTGIPLAWLANSVYILGSRDTGPLGRGLLPATSALGRLRNALLRFAGDHVVMRD
LRREADRTRARVNLARLRTGAMENIARPPALYLMGTVPSFEFPRGDLHPGTHFVGGLLGL
PPERFDEPSWWGELTGGRPVVLVTQGTTANDVDGLLAPAVRALADRDVLVVVTTGSALDV
DRLHPLPDNVRLERYVPYHHLLPHVDVMVTNGGYNGVNAALAQGVPLVVAPGSEEKPDVA
ARVGWCGAGVVLPRRALTEAGLRDAVSTVLNDERYRRRAQELAEEHRSRDAPRRAAELIE
SLAEHRGQIPTGGVTR
>A0A1C0U2B7|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Photorhabdus australis subsp. thailandensis|TrEMBL
MARIVIAAVATPGHVYPMLKVAESLIAQGHQVTVFTGALFRQQVEALSAQFAPFDEQIDF
DYRHLEQHFPNRAQLPPGNVQMALAFKNFFSAPIPLLDRQLRQIIREQQAELLIAENCFY
GILPLLQKEKAHRLPVIVVGITPLAYSSKDSVFWGPRIPPAVLPPELTHEQLVDETNQQL
ITEVQDSFNNSLIQSGGSALTRPFNDEMIFGADLFLQLSSLAFEYPRQGLPDTVHFIGPL
PNPAPKIESPQLWEEDDPRPLVVVTQGTISNTDLNQLILPTLHALATLPIRVLATTGGRP
VETLRKDLPENVCIEEFISFEHWLPQASLLISNGGYGTINYALSHGTPLLIADAGEGKQE
AAFRVVWAGCGINLETAHPTESQLKQTVENMLSTDLFKQRAQIVQKDYARHDALTAISNH
VERLTLA
>A0A5P9PTL7|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Amycolatopsis sp. YIM 10|TrEMBL
MKILLITHGSHGDVRPFVALAMGLREAGHEVVLAGPVSSVSVARPHCDHVHPLDDGTNNL
VHDRNAWEAVETNFRGLRGKKLGLAFLRQNRAAMAKVFEDLAVLTGDLATAGDIDLVVHQ
VNVPGQAIAEKLGVPAVPVCLQPFWVPTATFADPILPFRPPRFLNRASYLSTKLFVRGFT
GGTANWRTERLGLPRRRFAQDVFRRPDGSSAPTLQAFSRYVLPSPVRYPDSVHTTGFFFL
PAASDWTPPRPLAEFLAVGEPPVYLGFGSMVGSDPARTGRIVAEAVRLAKVRAVVAVGRG
GIRPGGSDERVFHLEHAPHDWLFPRMAAVVHHGGAGTAGAALAAGRPQVVCPFMFDQPYF
GRRLHEIGVAPPPRPLRHLTSRGLATAIHEAVHNRAFTARARELGHWVRAEDGVREAVKV
LESVT
>A0A231H5I1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Nocardia cerradoensis|TrEMBL
MTSVLLTATPVRSHVTPLLSVAEALIAAGDRVRFLTGTRFRDDVLATGAEFLPLPSEADY
DDRDIDAAFPGRRGLSGPAGIRYDMIEIFLRPVPAQLRAVREAIAAEPTDAVLAESMFAA
AAVLGGIPRSERPLLVNLGILPLALKHPDVAPFGLGIAPMRGPLGRLRNAVLTLGAEKGV
FAPVQRFANEIARAETGRALPRFFLDWPAGADHIVQFTVPEFEYVRRGLPDTVHFVGPVA
RSRPSAIPVPEWWDDLAGRRVVHVTQGTVATGEWNLIAPTVRALAHDDVLVVVSTGGRPV
GTLPNDLPANVRVAEFLPYDRLLPQTDVFVTNGGYGGVHYALEHGVPIVVAGRTEDKTEV
SARVAWSGVGIDLRTDNPTPDKVGGAVRTALTDERYRLRAKEIGDSIRRSPGPEAVHGII
ADAVRSAGRQRA
>A0A498QUZ7|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycobacterium pseudokansasii|TrEMBL
MHVAVVAGPDPGHSFPAIALCQRFQAAGDTPTLFTGVEWLDAAHAVGIDAVELDGLTATD
EDLDAGARIHRRAAEMAVLNAPALRELAPDLVVSDVITACGGLAAELVGIPWIELNPHPL
YLPSKGLPPIGSGLAPGTGIRGRLRDAAMRALTGRSWRAGLRQRAAVRVEIGLPAPDPGP
LRRLIATLPALEVPRPDWPAEAVVVGPLHFEPTDRVLSVPPGSGPVVVIAPSTAVTGTAG
LVEVALGCLTPDDTLPEGSRVVVSRLGGEDLPVPAWAVVGLGNQAELLTHADLVICGGGH
GMVAKTLLAGVPLVVVPGGGDQWEIANRVVRQGSGRLVRPLTAEALVAAVNEVLSSPGYR
QAAQQAAGGIAEVADPVQVCHEAL
>A0A498Q051|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycobacterium innocens|TrEMBL
MRVAVVAGPDPGHSFPAIALCQRFQAAGDMPTLFTGVEWLETARAVGIDAVELDGLTATD
EDLDAGARIHRRAAEMAVLNVPALRELAPDLVVSDVITACGGLAAELVGIPWIELNPHPL
YLPSKGLPPIGSGLAPGTGIRGRLRDATMRALTGRSWRAGLRQRAAVRVQIGLPAPDPGP
LRRLIATLPALEVPRPDWPAEAVVVGPLHFEPTDRVLAIPAGSGPVVVIAPSTAVTGTAG
LVEVALGCLTPGDTLPEGSRVVVSRLGGGDLPVPAWAVVGLGNQAELLTHADLVICGGGH
GMVAKTLLAGVPLVVVPGGGDQWEIANRVVRQGSGRLVRPLTAEALVAAVNEVLSSPGYR
RAAQQAAAGAAGVADPVRACHEAL
>A0A517U467|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Lacipirellula limnantheis|TrEMBL
MHLILSAFGSYGDVLPMVGLGAAVRARGHRVSVIVNPYFQSVVEGAGLEMLPLGTADEYR
ELMQHPDLWHPQRGLTLVLTRGAAHYLDEVYALLESQVTPGETVLAAHGLDMASRIYHER
HDVPLATVHFAPMALTTVHETSRYMGVPNMATWPRWAKRGVFWAADKWKIDPLIAPAVNK
LRARHGLPAVARIFTQYNNSPQLVLGLFPDWFGPMQPDWPPHTALVGFPLWDPPAEQQLS
AEVDEFLNAGESPIVFAPGSANVQATDFFQTAADVCVQLSRRGVLMTKYPDQLPQQLPAN
VRHFGFVPFSQLLPRAAALVHHGGIGTCAQGLACALPQVVMPMAYDQLDNGTRLARLGVG
AIVPEEKFKATRVAATLGALLASDEVRERCRDYAGRCDGAASLDAASDLLERLHARRGDR
VR
>A0A518I6Z6|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Gimesia fumaroli|TrEMBL
MRLMMIAVGSIGDVFPLLGIAREMRTRGHAVQVIANPFYTKHVEQVGAELLPIGTAEEHQ
QMMNHPSITHPRKGWALWLKLGSLNYLKQTYALIEEHAVKGETVLAGSWGAQAALVAREK
LDIPAATFHLEPDKFRTAFDSAALPRRSLVFQSNPPWLKRMQYRLLDKLLIDPAFSPVNT
FRRELSLPEIQHFWNAGIHSPDLTVGLFPDWWGPIQPDWPKQTKLIGFPLWDQNPDQQFP
EEVAEFLDAGEPPVVFSPGGFGNIPEKLFQIVVPVCEDLGLRAILLTSNRSLLPKQLPEA
IRHFQFIPFTPLLNRAKAVVHHAGIGTAALCLAAGTPQIAIPPMHINRDTALRLERLNVG
RMISPFSLREESLKQSLRVLQGADTISSNCQEIASRLKNSSTIPTAADLLESLVTNA
>A0A3E2MX49|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycobacterium marinum|TrEMBL
MRIAVVAGPDPGHSFPAIALCRRFLAAGDTPTLLTGVEWLDTARAAGVDAIELAGLVATD
EDLDAGARIHRRAAQMALLNAPALSDLAPDLVVSDVITACGGMAAERLGIPWIELNPHPL
YRPSKGLPPIGSGLAPGTGIRGRLRDTTMRALTARSWRAGLRQRAAVRAEIGLAEHDPGP
LRRLIATLPALEVPRPDWPAEAIVVGPLHFEPTDQLLKVPAGSGPVLVIAPSTALSGTAG
LAEVALESLIPGDTLPSGSRLVVSRLGGDDLVTPSWAAVGLGSQAELLTHADVVICGGGH
GMVSKTLLAGVPLVVVPGGGDQWEIANRVVRQGSARLIRPLGADALAAAVNEVLSSPGYR
EAAQRAAASIADVADPVQVCHEALALAG
>A0A518D7R0|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Pirellulimonas nuda|TrEMBL
MRLILSGLGSYGDVFPMIGLGAAMQRRGHGVTLLANPYFRSNVESAGLTLAPFSTEAEYL
RLTQEPDLWRPRGGMQVIFRESMQQLRPLVEQVRGMVASSSEPAVLVAHPLDMASRIVSE
QLGTPLVAVAYAPMALWSRQSPPRLAGVWVGRGTPKWLLDAQFWLGEKLLVEPTVRRPLN
LLRAELGLPPIGRVFPEWWYRADHVLGLFPEWFATASGEDLPGDWPQNLTLAGFPFWDGP
IPADGAQRPPLPAEVEAWLASGDRPIVFAPGTANRAAGPFFRAAIDACARLGRRGVLLTK
YAEQLPDPLPDHVRSFEFVPLSLLLPRCAALVHHGGIGTTSQGLAAGIPHLVQPMGFDQP
DNAERLAHLGVGDSLRPARFTGARVAARLDALLSSRTVPKACGRLAERCRENDPFAAACL
CLESLAGS
>A0A7Z7N9A2|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycobacterium simulans|TrEMBL
MRVAVVAGPDPGHSFPAIALCQRFQQAGDTPTLFTGVEWIEAARAAGVDTVELDGLAAID
NDVDAGARIHRRAAGMAVLNVPALRELAPDLVVSDVITACGGMAAELLGIPWIELNPHPL
YLPSKGLPPIGSGLAPGTGIRGRLRDAVMRALTARSWRAGLRQRAAVRVEIGLPARDPGP
LRRLIATLPALEVPRPDWPVEAVVVGPLHFEPTDRVLDIPPGSGPVIVVAPSTAMTGTIG
LVELTLQCLRPGDTLPPGSRLVVSRLEGPDLALPSWAVAGLGRQDELLTHADLVICGGGH
GMVAKTLLAGVPLVVVPGGGDQWEMANRVARQGSARLIRPVTADALVAAVNEVLSSPRYR
EAAMTAASSVGGVADPVRVCHEALALAG
>A0A3G8JGU2|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Gordonia insulae|TrEMBL
MNARTYLFALVDGGGTVPPELGAARRLVERGHHVTVLAEDSMASDVHATGATFIPWTTAP
NRASRRPEDDPYRDWECTNPLELFGRLLEYQFAGPAPAYAHDTAHAIDTVKPDLAVCSFF
AVGAMVAAQARGVPFDVPFPNTYLLPVEGMPPSGLGLTPAHGPLTRLRDRVVRSLTLRQW
NKGVPALNAVRATYGLPPVEGFFDQANLARKHLVLTSAEFDFPARMPARVRYVGAVLDDP
AWTSDAPWTPPPGDAPLVLVALSSTFQDQVGCLQRVIDALAELPVRGYVTTGPAVDPGAL
TAPDTVTVVEAAPHSRILPHADAVITHAGHGTVVRTLAAGVPIVALPHGRDQADNAVRVS
VRGAGKTLSRKASARKIAAATQQVLGDSAYADAAARLGAIIRHDAEAGALVAELEEIEVT
ETSVTGG
>A0A6N7CA40|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Rhodococcus sp. T7|TrEMBL
MRVAVVAGPDPGHAFPALALCLAFIGAGDEPVLFTGTRWVEPARAAGVPAEVLKGLAPRP
TDDDLDAGARIHARAAHISTELLPDLRAMGPDLVVSDILTAGGGMAAERLGIPWVELSPH
PLYAASRGLPPIGSGLAPGVGIRGRARDTLMRAATARSIRQGERQRSEARVGVGLPAKDP
GPVRRLIATLPALEVPRPDWPAEAHVVGPLLWEPTNEVLEPPDGTDPLVMVAPSTAFTGA
EGMLETTLAGLDGAGVRVIASILDGSSAAVPPWVRAGLGRQDAMLREASVVVCGGGHGML
AKALLAGVPAVVVPGGGDQWELANRAARQGSAVVVRPPSAEALRAAVDRVLSNGAHAEAA
QKAARSIADVVDPVEVCRDALR
>A0A221W338|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Actinoalloteichus hoggarensis|TrEMBL
MGAGDTMARVLIAAVPFFGHVRPMRLIAADLVARGHAVTFLTGAAFRAAVEGTGARFVPL
PAEADVRPDRFPDRRRIPTGPARLEYDNQHLFVAPMAAQHAALQALLAEDAAPAVLLHDT
MFLGAWPVRHGAAGVRPAAVVGIGVMPLPMNSADHPPFGSGLVPDDSEEGRARSRVLTEK
AEAAERAGSHRLLTRAFERLGAAEPPPLLSQGLVGVPDLFLQLSIESLEYPRGDAPSHLR
YIGALPPERGEARALPVWWDDVTRANRVILVSQGTIANDDLGRLIEPTLRALADLDAVIV
VATGRDAVPATLPANARVAEFIPFDTVLPHVDVLVSNGGYGGVQQALRHGVPLVLAGDTE
DKIEVCAKVSWAGAAVSLGTGDPDEADIRKAVDSVLDDPLCRDRARELRAEYEAHDPRVA
IADAVDGLAVRRG
>A0A428CF73|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus oralis|TrEMBL
MRKIKIDVVVVPLSGHLFPTLNLLAPLLKDPLYEIRLFTGPQRKAVAEEMGFQVIPILEN
CVDEFERVANNEGQLNLFSAYRQLSASLDLINVVSDQLVQEWQGNRPDIVIADFITLSGG
LVAEQLNIPWITTMATQFAIETTDGPPCFFGGMGSPKASFQSAQQWLGRKGTRLGKRIVS
FLLRERLKRYDFKLYNQKGQETIYSPYSILGIGMKELELKSGFPEHYLWVGPFGSSIERA
ENYPFDLSPYAGYKKVLVSCGTQLAWAKDNLLYQTQQLAKAHPDCHFFVTLGFGGQDFQC
EEVMDNVSVVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIYGKPALILPHDYDQYDYAVRG
LEAGIALTAKREDREAIGRAFGELLARDGWSDLNKLSRAAQIYQPTEILKSEIHRLLGDK
EK
>A0A3R9KE61|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus oralis|TrEMBL
MLGRTIILVVLFLKICYSRHMRKIKIDVVVVPLSGHLFPTLNLLAPLLKDPLYEIRLFTG
PQRKVVAEEMGFQVIPILENSVDEFERVANNEGQLNLISAYRQLSASLDLIDVVSDQLVQ
EWQENRPDIVIADFITLSGGLVAEQLGIPWITTMATQFAIETTDGPPCFFGGMGSPKTPF
QSVQQWLGRKVTRLGKRIVTFLLRERLKRYDFKLYNQKNQETIYSPYSILGIGMKELELK
SGFPEHYLWVGPFGSSIERAENYPLDLAPYANHKKVLVSCGTQLAWAKDNLLYQTQQLAK
AHPDCHFFVTLGFGGQDFQCEELMENVSVVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIY
GKPALILPHDYDQYDYAVRGLEAGIALTAKREDTEAIERAFDELLARDDWADLNKLSRAA
QIYQPTEILKSEIHRLLGDKEK
>A0A399H4E5|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces sp. YIM 130001|TrEMBL
MSRFLLVVPPLVGHINPLAGVAAELGRRGHEVAWCGHAERIRSLTDDRAQVHDAPLPEGG
DLSRPPGLTGPGAFRFLWEEFFVPLAESMAPHVERAVSEFRPDVVVTDQHAVAGALVPER
LGVPYLTSASTSAELVDPLAELPKVAAWLADRLDALRQRIGDPSADHDPRFSPYGILAFT
SRELLGDADLPWERVHLVGPVIAERPEDPDFPWDDLDADRDLVFVSLGTANTEAGQRFLG
ETVEALHHLRDRVQGVFADPGGHLGELPAGMLARPQVPQLDLLSRAKAVISHSGHNTVAE
SLWHGLPLVLAPIRDDQPIVAAQVVAAGAGVRVRFGRVKAPRIAEALTTVLDDAEGHRTA
AAAIGRTLRAGGGQHTAATHLERLAAQPVTAATVRS
>A0A518H4T8|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Tautonia plasticadhaerens|TrEMBL
MTAQTDPRPTADDTSPSPDAGRRPTARRIVLGTFGSLGDVHPYVALARELKRRGHRPSIA
TSAYWRPKVEQEGIDFSPVRPDAPDPDAMHDLMARLFDPRRGPKVVISEVMMPSLRESFE
DTRAAAEGADLLVSHPLTFAVRLVAEAGGIPWASSVLAPMSFLSAFDPPTLPAAPALSGL
RRLGPRFHRPLFRGFRLLVAPWERPWRRLRAELGLPPTGESPVFEGQHAPDLVLAMFSKL
LGAPQPDWPPNAVVTGFSFFDRDSAEDDSPEELLRFLDDGPPPVVFTLGSSAVWAPGRFF
NESLGAVRRLGCRAILLTGPEGANARPSGLPPGVLATGYAPYSGLFPRCAAIVHQGGVGT
TAQAMRAGRPMLVVPHGFDQHDNADRVSRLGIARTLSRPRYTASRVADALRPLLDDPGFA
SRSAEVGHLVRAEDGPAAAADAIEALVSRGRAAR
>A0A7G6V6K9|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Burkholderia cenocepacia|TrEMBL
MAKMIVTAIGSAGDVHPLLGVARTLAARGHDVVFCTHVPFEAAVRRCGFAFVPVGTAAEY
DAAMANPALWNPRTSFRTLWQVIAPTLRPHYDALRALTDADTVLVGTLWAFSARFMQELH
GTPYVSVQVSPSTLLSAHAPPTHPRLTIPARWPLPVKSALMTLIERQVLDRVCGPALDAV
RRELELAPARRVLGRWLHSTDGVLCLFPGWFAPPQPDWPSNHLQSGFPLFNDIATPDDDG
ALDAFLAAGEAPVVFTAGSTLVDHAAYARAVADALRATGARGILLTPHDAVQGDDRLLVR
RFVPMRTLLPRCRALVHHGGIGTAALACEAGIVQVVTPFAHDQFDNAQRVVANGCGVRVD
GPLDGARLGAALARVLDEPAFAVHAERTRALLAAAPDGCGAAADFIERFVPRRGRAAARA
DVAVAGA
>A0A142X3P8|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Planctomyces sp. SH-PL14|TrEMBL
MEFLLLPQGSSGDVNPFIGIGRELQSRGHSVTLATGEYFREPVEQAGLQFSPLGTIEQYN
RILRNPDLWHPSRGTKVVFADPDVYEGIRAGHRLTTEFHERHPSGVVAAGSLAMGARVAK
ETHPGLKLATLHLQPCMLRSFVDPPVLAGVRFPTWVPRGVVRGFFWLGDRVVDGHLSTTL
SRFRKELGLPEHHRYLKDWIHSPERILGLFPKWYADAPDWPGHFQQTGFVQEDAAGELPG
DLKDWLDAGPPPVVFTFGSAMIHGAPLFRGAVDACRILGCRGLLLTKYPEQLPEPLPDHV
RHERYAPLLDVLRRSALLVHHGGIGTTARALQAGIPQIIVPLSHDQFDNVQRIERLQAGT
SIPRGSFVGRRVATVIGRCLGDAGMKQHATRASERFAGPTGNELTATALEEFASGQPPGR
D
>A0A3Q9J139|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Microbacterium lemovicicum|TrEMBL
MTLLVISPDYASHLLPLAGIATAWRDAGERVVVATGPATAPVVAQFGYDRVNLPLGRGAN
PGVIRSDEQVAAEAQSLEGFFAATRLGMVETLTYQARERLTDLMWQPVDRARATLAVIEE
VRPDAILVDHLAFSARLALHTRGIPYGDVVLGHPTALPVGDEVYGCPPSWPAAFDPGDEQ
LAALRALCERVATGFTAQWNEAARELDAAASPVDDAFALRGDTVLYNYPVELADGDGRVL
PPHRFLGSVPRDEAREAHVEEWLATGEPFVYVSFGSFLSVRADVLARVAEALRRAGLRAA
IATGSTDPAELGPVPAGWLVAAYLPQVRLLSAATAAVTHGGNNSVTEAVGSGVPLVVLPF
STDQFAGAAALERTGAGIALDPNAADVVALTRALMAVVDEGFRGRAPLAAAAEAQAERPG
PQIAFETLSGSV
>A0A3N6E880|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces sp. ADI96-02|TrEMBL
MSRFLFVVPPLVGHINPAVGVAAVLASRGHRVAWAGEPALIRRLAGPDAVVHPCPPPGSE
LGWEEGPVAGRPPDVRGPEALRFLWERFLVPLAEAMAPGVRQAVAAFRPDVVVADQQAMA
GALVAEDLGLPWATSATTSAEFADVLATMPRVAAWNEALLRDLRARIGDPAGSGDPRFSP
HLVLAFTTPELAGPAARGGDRVRWVGPSLTARPFPAAFPWDRLDPGRRLVLVTLGTANTD
VGARFLGRAAEALRARADRVQAVIVDPEGTLAGSAPGGPDRERDVIALPAIPQLELLERA
DAVVCHAGHNTVCEALWHGVPLVVAPIRDDQPVVAAQVADAGAGVRIRFGRSGADAIGAA
VDTVLDEPHPRAAARTIARAFRDAGGAPAAARHLERLADGRMEDK
>A0A5S9P4E8|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycolicibacterium vanbaalenii|TrEMBL
MRVAVVAGPDPGHAFPAIALCLRFLAAGDAPTLLTGRKWLEVARGQGIGAVELDGLDPTS
VDDDADDGAKIHQRAARMAVLNTQRIADLAPDVVISDSITTCGGLAADLLGVPWIELNTH
PLYRPSKGLPPLGSGLAPGTGLRGRMRDSVLRALSARSWRAGLRQRAAARVGIGLPAHDP
GPLRRLIATLPALEVPRPDWPGEAVVVGPLHFEPTTSVLPLPPGDGPVVVVAPSTATTGA
KGLTELALETLIPAQVLPAGARVAVSRLEGPEGELPPWAVVGLGRQDELLSAADLLICGG
GHGTVAKALLAGVPMVIVPGGGDQWEIANRVVRQGSAQLIRPLTGAALAAAAREVLATPR
YREAARQAGATATQVADPVRVCHEALQGSA
>A0A1K2G1F7|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces sp. F-1|TrEMBL
MRILCTVTGKPSHARAMLPLARACAEAGHEVLVVVPPELTHVFAHEPVSVLGALPAPGSS
SRVGPKLADTFRALLPVARDFGPALILRDGTEFAASFVGEELGVPHLPVPSGSGNVFDPA
LVLAPLNERRAEVGLPTTDDPHAIFRYGRLDCMPPDHSFIANPTPHTFAYRQPATVDRAE
RLPGWVAQLPTDKPLVVAAIGTALPQFKDLRPQDHNIPLDRWAKYNPTTLLNAMVAGLSR
VDCVAVVATGGVPVEQERVAGNVHLVESFAQPLLLQCAQLMLTHGGYNSIRECVGAGVPM
AVLPVFGDQPQNADRVEELGLGTRVRDVDAAEIAKGCEQVLQDPEFTRRARSAQRRMLAL
PSVADAVAELERVAAERSPLRGA
>A0A3R9M946|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus mitis|TrEMBL
MKRIKIDVVVLPLSGHLFPALNILAPLLKDPLYDIRLFTGPQRKAVAEEMGFQVLPILEN
FVDEFERVANNEGQLNLISAYRQLSASLDLINVVSDQLIQEWEKNRPDIVIADFITLSGG
LVAEQLGIPWITTMATQFAIETTDGPPCFFGGMGSPKNPFQFAQQWLGRKGTRLGKRIVT
FLLRERLKRYDFKLYNQKNQETIYSPYSILGIGMKELELKSGFPEHYLWVGPFGSSIERA
ENYPLDLSPYASYKKVLVSCGTQLAWAKDNLLYQTQQLAKAHPDCYFFVTLGFGGQDFQC
EELMDNVSVVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIYGKPALILPHDYDQYDYAVRG
LEAGIALTAKREDTEAIGRAFDELLARDGWSDLNKLSRVAQDYHPTEILKNEIYRLLGDK
EK
>A0A3N6H5Z8|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces sp. ADI98-12|TrEMBL
MDSAARPILFVSLPESGLLNPLLVLAGELARRGVADLWFATDEHRRADVEALSAVSGVSF
ASLGEVVSELSAVTWDDEVYREVTQSSRFKAHRAVVRQSYRPALQARKYRELEKVVDEVR
PALMVVDCVAGFAVDLALARGIPYVLNVPFVASNVLTSHNPFGASYTPKNFPVPNSGLPA
RMSARQKLANTMFRWRTLGMFLHPEMGRLLREDAALRKELGIAPPNAMTRVDEAAAVVCS
SIAELDYPFDLPEKLNLVGAVLPPLPEAPDGDEVSKWLDEQSSVVYMGFGTITRLTREEV
GALVEVARRMSATHQFLWKLPKEQQHLLPADGSLPANLRVESWVPSQLDVLAHPHVSAFF
SHGGGNAYHEGVYFGKPQVVRPLWVDCFDQAVRGRDLGISLTLDKPHTVDPDDVVDKLTR
VTAEPSFREEAERLGALQREAGGRETAADLVTGLLPAA
>A0A2K8PQP1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces lavendulae subsp. lavendulae|TrEMBL
MRILIATAGSRGDVAPYTGLGVALSRAGHEVALAATGTFEPLATEAGLEFRPLPADHRAH
GSARGKRELLRAAAAFVTDLGEGFAGAVDRGTDVLLLSATTAPLGWHVAEAAGTPSMGVY
LQPTTPTGDFPPTVTGTRSLGRLGNRAAGRFALHMADRVFEPAVARLRARLDLPPLTAAR
MRRRQAQARWPVLHGFSTALLPRPSDWAAGLAVTGPWWPYVGADRRLPAELEDFLAAGPP
PVLVGFGSMAAGEGERLGEIAVRALRRAGLRGVLQSGSAGLAADADDVLTVGDLPHALLF
PRLAAVVHHAGAGTAAAALRAGVPSVTVPVTADQPFWAGRLAAVGAAPVPIPFRSLTAEG
LGDALAKVVREPSYAAAAAAAARHIAVEDGEAALVSAVGRLIG
>A0A1V5JK24|4'-demethylrebeccamycin synthase|EC 4.3.3.5|bacterium ADurb.BinA028|TrEMBL
MTAVLAYTSPAMGHLYPMMPLLLELRDRGLDVHVRTLDTLVDQARAAGLSAERIDARLRP
IADKHPDWAATNAKAALERSATMFAERAVLDGPDFRRAIEEVDPDLLIVDTNAWGALVVA
EAQRRPWLHFSPYLVPLRSTGTPPFGPGLPRWDNPVGRVRDAVVGRLVFGAVERSIIPRI
NALRTPAGLAPVRSFDDLVLAAPLVAICSATPFDYPHPDWPSHVISIGAMTWEPPTAPPA
WLADLPDPLTLVTTSSEYQADEALARVAVAALASEPGSLVVTMPAGVPDDLRDLPPNVRV
EQFVPHAPLVARAAVAVTHGGMGATQKALAGGIPVCVVPYGRDQLETAARVVHADAGTQL
APKKLTPAALRAAVRAAAGKRAGAAACADGFRAAGGARAAADALLAQLASPSRR
>A0A518EPE1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Planctomycetes bacterium Poly30|TrEMBL
MSADRSSLRIDWVSPPFAGHLFPILTVAQGLWQRGFHGQRILSTPSACSAAAECGLPFVP
LLAGKESHILGIANTETRVGASPRRLLRQFKDTLGVLGVLGEELEREWSSDPPRVVIADR
VLPTAGFAARAAGAAWWTSMTSVCPTETRTGVPAYLGGLDQGSGPWRRIRNGAGRAATRT
FKRSAAWLARRELRAIGLERIYRSDGTEAFYSEEKILAFGLPEFEFERRDWPPALEFVGP
ALGSPIDRGRAPGDVPPVDPGTPHVLVTIGTHLLWAKERAASAALELSRRLPGWVVHFSR
GDARPGAQSAGVRQTGPRCFEIPYVPYDAALARYAAIVHHGGSGISYAALASGVPALVWP
HDYDQFDHAAQIVHHGFGLRTNGEPAQMAHDLLRLHGEPEFRGRVVWMAGQIAASDPVEA
SAAALDRLSSPPE
>A0A517RA40|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Gimesia alba|TrEMBL
MRLIMIAVGSIGDVFPLLGIAREMRTRGHAVQVIANPFYAKHVEQVGAELLPIGTAEEHQ
QMMSHPSITHPRKGWALWLKLGSLNYLKQTYALIEEHAVKGETVLAGSWGAQAALVAREK
LGIPAATLHLEPDKFRTAFDSAAMPRRSLVFQSNPAWLKRMQYRLLDKLLIDPAFEPVNA
FRRELALPEIQHFWNAGIHSPDLTVGLFPDWWGPLQPDWPQQTKLIGFPLWDQNPDQQFP
EEVAEFLDAGEPPVVFSPGGFGNIPEKLFKIVVPVCEELGLRAILLTSNRSLLPKQLPET
IGHFQFIPFTPLLNRAAAVVHHAGIGTAALCLAAGTPQIAIPPMHINRDTALRLERLGVG
RMISPFSLREESLKQSLRVLLGADTINSNCQEIASRLENSSTIPTAADLLESLVPKA
>A0A0H2LV09|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Variovorax paradoxus|TrEMBL
MASYLIAATALPGHVLPMLAIAQHLVALGHEVRVHTASQFRAQAEATGAGFTPFAPAIDY
DYRDLDKRFPERQRLSSAHAQLCFGLKHFFAGAMAAQHAGLRSILDGFEADAILVDTMFC
GTFPLLLGPREERPAVVAIGISALPLSSCDTAFFGTALAPSSTPEGRARNRAMNANLKQA
MFGEVQRHFDGLLARSGSPALPEFFVDAMVKLPDLYLQLTAPSFEYPRSDLPASVRFVGP
LLAPASRGFTPPDWWHELDDGRSVVLVTQGTLANQNPAQLIGPTLQALAGDGNVLVIATT
GGPVPPALAANLPANARVLPFLPYDRLLPKVHAMVTNGGYGSVNHALSLGVPLVVAGTSE
EKPEIAARVAWSGAGINLGTGQPGARQIGDAVRKVLGESSYRQRAAALREDFARHHALAG
IAEALAALRRTTPASAEMA
>A0A231HFG0|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Nocardia cerradoensis|TrEMBL
MRVAVVAGPDPGHAFPAIALCLRFLQAGDDPVLFTSPRWFDAAREAGIAVRRLKGLAPRP
QDDDADAGARIHDRAAHISSEILPDLSAMLPELVVSDVLTAGGGMAAERLGVPWVELSPH
PLYLPSKALPPIGSGLAPGEGLRGRMRDTVLRGLTARAITRGDRQRGAARASVGLPELDP
GPDARLIATLPALEVDRPDWPEDAHVVGPLLWEPTSEVLVPPPGDRPLVMVAPSTARTGF
GDLAIGALEALADSDVRVAISMLDTPPQDLPPWATAGLGRQDELLRHAAVVVGGGGHGLL
AKTLLAGVPIVTVPGGGDQWELANRAFRQGSSQLVRPFTPESLRAAVHTVLDDESYRKAA
AAAAATASDVADPVDICHRTLDRARAS
>A0A4R8SIN7|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycobacteroides salmoniphilum|TrEMBL
MKGSAMKFVLSFYGTRGDVEPGIAVGRELLRRGHDVRMIVPPDLVAFTEAAGLSAVACGP
DVRVWQDVNRDFWARFLRNFWKNFWRIRDLRELLREDWRLLVQCWEDVSSTLRSQAADAD
LLFTGVLGEESAGNVAEFYSLPFATLHVFPIRANGQLVPGMPARLGRSIMRLSEWLGWPM
FKRLEDPQRRELGLPKATGPSPWRIAERGSLEIQAYDEACMPGLAEEWAEYDGRRPFVGA
LTLDLPTDSDAEVASWIAGGEPPICFGFGSMPVESAAETLAMISAACEQLGERALVCAGG
SDFSHVPLFENVKVVGMMNYSAAFPACRAVVHHGGAGTTAASLRAGVPTLVLSTDLDQTL
WGARVKRLKVGTARRFSATTEKTLVADLRTVLDTQYVTRAREVATRMTKAAESPVTTADL
LEDFVRLKRAG
>A0A1F2Q0F7|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Rhodococcus erythropolis|TrEMBL
MRVAVVAGPDPGHAFPAIALSLALIQAGDDPILYTGTRWVEAARAAGVEAEPLKGLAPRP
GDDDLDAGARIHSRAAYISTELLPDLKSVSPDLVVSDILTAGGGLAAERLGIPWVELSPH
PLYSPSRGLPPIGSGLAPGIGIRGRLRDTLMRAATGRSIKQGLAQRSQARVGVGLPALDP
GPNARLIATLPVLEVPRPDWPERAHVVGPLLWEPTEVILDPPPGDEPLVMVAPSTAHTGA
VGMFEGTVEGLGGAGVRLIASMLDGAEGEHPDWVRAGLGRQDAMLRDASVLVCGGGHGML
AKALLAGVPTVVVPGGGDQWELANRAARAGTSVIVRPADARSIRDAVLQVLSDKRFAEAA
MSAAATASQVTDPVAVCRQVVNGGVTA
>A0A5B9VZ08|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Aquisphaera giovannonii|TrEMBL
MLRDSFEDLRAAVWGADLLVTHTMTFAGPIVAACEGIPWASAVLAPASLMSRFDPPVLSQ
APWMSRLRPLGPRFHGPVLRHGMALAGRWVPEVDQLRADLGLPPGDNPLGDGQHAPGCVL
ALFSGVLGVPQADWPPQAVQTGFPFLDAPQPETDPDLERFLDAGDPPVVFTLGSSAVHDA
GRFYAESLDAARRVGRRAVLIVGPDPRNRLRGRLPSWAFEAGYADHGSLFPRAWAVVHHG
GVGTTAQGLRAGKPMLVVPYTFDQFDNADRVVRLGLAASISSRRYNASRSARGLGRLAEP
GCQERAARIGRAVRAEDGVETACRRLDALIASRGAGAPARSANPRWRTWARPGGRD
>A0A5C5YSM7|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Posidoniimonas polymericola|TrEMBL
MRILILTVGTRGDVQPYLALAKGLLAAGHNVRLCTCGRFESFAAAHGVDFAAINNDLLDF
MDSDLGRSVMETTTNLFEMVRTVRRVWPTVGPMIRRHIDEMAAVAMAYRPDLILFHKKAI
GAEDFAEKLGCRCALAFYLPMYVPSSHAPAFGLPRLPLGSAYNRLTYRFINAVTKASSAS
FARPWRKRQGMSPRGRYRRHADGSPIGAIHAYSPSVLPEPSDWPEWAIVSGYWFLDGPED
YSPPAELRAFLAAGPPPVYVGFGSIFGRDPRGKAKAVIEGVRRSGARAILASGWGGIDLT
DLKLPETMLAIESAPHDWLFPRVAAVVHHGGCGTTGAGLRAGKPTIVCPFFADQPFFADQ
PFWGRIVHELGVGPKPILQRRLTADKLAAAIRSTLADEAMRAKASALGETLRSERGVENA
VAFVERYMAGQ
>A0A5C5VUE5|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Phycisphaerae bacterium RAS1|TrEMBL
MFVWISTGGSHGDVHPFLALGQTMQRRGHRVVLCVHPHFRDDVLAAGLEHSPIGEHVDVP
AILNDPDLMHHRRGGGRVLDLILGSVPAGLRTLRDAWRNDRPDVVVAHHICIGVRWVCNE
LHIPLALCTLAPLLWFSPRDPVPVFQRRHGRAAAAIARAMLPCVKPLASWIVGRRVNRIR
RQCGVAAERNAFWADMHGGDALLGLWSPHYRAPTTADPPRSLVCGFTWYDRSDREPMLPP
ELERFLSRGQPPIVFSLGTAAVYHPGDYYHIAAETCQRLGRRGVLLVGKDANAPPDLPAD
ILPVHYAPFSLLLPRAAAVVQHGGIGSTAQSLRAGCPQVVVPHAHDQFHNALHVRRLGVG
LNTPRVGLNARKLAAALAPVASDPAFRRHADRLAGLLRNEDGARVASEAVEKLVADSAAR
RGGA
>A0A5P9PQH9|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Amycolatopsis sp. YIM 10|TrEMBL
MRILFTFAGGTGHFNPLVPIARAAEAAGHQVAFAGQAVMVDTVRAAGFTAYDTGGDTFGA
RERMPLLAIDLDREELALREGYARKVAGERCPRVIEVCREFPADLVVCDEADFGAVVAAE
SLGLPHATVLVIAAGSLIRPGLVGEPLNELRARHGLAPDPDTAMLGRHLVLSPFPPSYRN
PDFPLPPTAHSLTLDPVVPDLAPPDWLRTDAPTVYFTLGTVFNTESGDLFHRVLAGLREL
PVNVVMTVGPHIDPAEFGPQPDSVRIEQYVPQASLLPWCAAVISHGGSGSVLGALAHGLP
MVLLPMGADQPHNAERCAGLGVAKVLDVLDATPAEIGAATQEVLQDSGYREAAARMRDEI
ATLPDAGHAVRLLEDLVRAQ
>A0A517YU11|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Poriferisphaera corsica|TrEMBL
MRVMIATVGSRGDVQPYVALGVGLKEAGHEVVVCCPSSFKEFVEGYGLRYGYMNNEVIDL
IQSDLGKELTENLTNIVKTINAFFRLYKQMGPMQQRMIDDGGEVAKEFEPDVVVYHPKAS
GGPWYAELVDGKAMMAVPMGMMVPSGEKPCIGFPNLRLGWLNRLTYKLVMWLSMKGIRKH
IEAWRENMGLKGRSIYRNLVFKRDGEMLPVMHCYSGLVGDEPRDWPEQSVATGYWFLERN
DGWIADEGLVKFLESGDGPIVYVGFGSMSGKNPERRAKAVVEGLLKAGARGVISKGWGGM
ASGELPDSIYEIDDVPHDWLFEKVDVVVHHGGAGSTAAGLRAGKPTIVCPFFGDQPYWGK
RVWELGVGPRPIPQRKITGEKLTQAIREVLSDEKMKQKAKVLGEQLRVENGVGEGVKFVE
KYGANERVY
>A0A0J6VIT1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycolicibacterium chlorophenolicum|TrEMBL
MATVLAYTSPALGHLLPMSALLAELMARGHQIHLRTLADGVEAAVVQGFSTAPIDPRIEE
VEMDDWRATNPVSALRLSVSAFSRRAPFEVGDLRAAIAEVAPDGLLVDVNCWGAQTAADA
ADLPWASFSPYTPALDVEGVPPFGLGLRPVRGILGRWRDAVVRAAINRPLQRPAVAAINA
IRAPLGASPVASLDDFLRRAPLLFLATGAPFQYTADWGSNVHMIGPCIPEPVAGEPPEWL
SSIDRPIVLVTTSSERQNDADLVSAAAAALADDPVHVVATLPAGTPDDVTDRPHVTIRRF
VDHDLVLARAVCAVTHGGMGGTQRALARGVPVCVVPYGRDQFEVARRAEVAGCGTRLPAR
RLSVPRLRRAIHEAMTMGPGAARVAEGFRATGGVARGADLFEQLMER
>A0A3G8JIU4|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Gordonia insulae|TrEMBL
MARVAIVAGPDAGHAFPAFALADRLTGDGIETVVFTGTRWCARAGNRGLDVAELPGLVAR
DADDDTDAGAKLGRRAARIAVELAPLLAQRAIDLVISDVITVGGGWAAELTGIPWVELSP
HPLYLPSRGLPPIGAGLAPGTGVSGRLRDTAMRVATGRSLRQGERQRALARADIGLVGRG
GPAARFVATLPALEVPRPDWPEDTHLIGPLLWEPTDALFDRPAGTGPLVLVAPSTAVTGA
ADMGTVALAALSSDNLGIPVRVVFSALHVPAGVDHADHVVAGTARQDEILADTDLVVCGG
GHGMLAKALSAGVPVVTVPGGGDQWELANRVQRQGSGLLVRPVEVGSLSSAAGRVLTEPA
FAAAAGRASASVDGVVDPVRIVRRLLRLRRDRVAARR
>A0A3N6GZL2|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces sp. ADI95-17|TrEMBL
MSRFLFVVPPLVGHINPTVGVAAELVASGHAVAWVCPDPALVGRLAGPGAGPVMACAGAP
RGERPTELRGPEALKFLWERYLLPLAESMAPGVRAAVEAFRPDVVVADQQAFAGALIAER
LGLPWATSATTSAEFTDPLAGLPKVGQWLQQRLGALREAVGDPAGTADPRFSPHLVLAFS
TPELAGSAHDGVCWVGPSITARPSAAGFPWEWLDAGRTTVLVTLGTANADVGGRFLDMCR
SALRERADRVQAVIADPGGVLSARDGDKDVLIVPSVPQLSLLERGVGAVVCHAGHNSVCE
ALWHGVPLVVAPIRDDQPVVAGQVVDAVAGVRVRFGRVTVQKLASAVDSILDDPEYRDGA
HRIRTAFRSAGGARAAALHLGDLAVRQVVSAAARDGSAMSTRAAPTSRDTLAHRESADAA
PRRTGTAREFR
>A0A517VZ12|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Gimesia aquarii|TrEMBL
MNILIITVGTQGDVQPYVALGKGLKASGHSVTVCTCAYFESFVTAHGLDYAFMNDDLIKF
MHSDDGKIAMENTGNLWEAIRTAIKIIPTVGPMQRRQIDDSWQATQAVHPDLVLYHPKAL
CAPDFAERLNVPSIIGFYLPLFAVTGDFPAMGLPRWKLGRWYNRFTHRLINKATWWGMRK
HISAWRKENNMPRKQGIDFLNQSDGQPAPALYAFSESVIPRPSDWPENARVSGYWFLNQI
DDWEPPAELQEFLANGASPIYFGFGSIFGQDPLRLTKIIVEAVKTTGARAILARGWGGLD
LDQIELPETIFKLNFAPHDWLFPQVAAVVHHGGCGTTAAGLRAGRPSILCPFFGDQPFWG
SIIENLGVGPTPLPQKKLTVEKLSTAIRQVTTDTAMIEKADQIGQRIRSEDGVANAVEFI
DQWLARYSESSLVDRRSDGLQ
>A0A4R8SPU5|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycobacteroides salmoniphilum|TrEMBL
MRVAVVAGPDPGHAFPAIALCLKFAAAGHDPALLTGTRWLDQARSAGVESIELLGLQPRA
EDDDLDSGTKIHQRAAYMATANVDQLRELSPDLIVSDVITACGGMAAELLGVPWVELNPH
PLYLPSKALPPLGSGLAPGVGLRGRLRDVLMRKLTQKSINEGLSQRSQARVGIGLSAKDP
GPVRRLIATLPALEVPRPDWPDEAVLVGPLHWEPTDVVLQPPSGSGPVVVIAPSTAFTGA
EGMTELALQALESAGARVVVSALDPAASGLPPWTVAGLARQDLLLAGADLAICGGGHGFL
SKALLAGVPVVVVPGGGDQWELANRVVRQGSAELVRPLNRDSLTAAIGRVLGAPRYTEAA
RRAAAGAVDVQDPVRVCQHAVAALK
>A0A7L4ZGU3|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Kordia antarctica|TrEMBL
MNILFCSQPQIGHLHNLIPLAKKLQSKDVTIIFATSKSLKNEIEHLGFKHEPMGIDFMGF
GDLQVELKKRNIIPKDEPFSLKLFVNPLATLSLNEIEKIALKYKPKMIIRDPVEFSSLIV
AEKHDIKTLTINWGYNFPLEKSIKKCFLEIDNLRIKSGLKSDIKLDFLMKQKYINLLPEK
WYDKSFIENYNVSYYKSNSYNSISKKNNVSVPNNIIYATLGTVFMNKDIISVYIDAFKQV
KEQFLISYPVRNQFPTIKNILFYQYIPNNHVLPKAKLVITHGGFNTIRQALSLGIPLIIT
PITGDQKVYAKKIENLGLGIAINKKDLTSSKLIESINKIKNNSKFKFNALKFKNEINNLD
DINVLVEKLLV
>A0A7G2D7D9|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Microbacterium sp. Nx66|TrEMBL
MSRYLLTCTPAHGHVLPLLQVARHLVAGGHEVLFLTSSRYEERVTAAGARFRPLPAEADV
DLDDANGAFPEREGLTGAAALRFDMSTLFIRPGRAQHEAVRVELARNRIDAVLTEPLFVG
AALLQRLPKAERPPVVVLGIFPLGARSVDTAPFGLGVTPMSGLFGRVRNAFLRLVAERVI
FGGVQKEADAMAREAVGRDLGGFVLDWAGRADAYVQFSVSAFEYPRSDLPASVHFAGPLP
AAPSTAPLPDWWSDLDGRRPVIHVSQGTIANADFGQLVLPTIAGLAATDALVVVSTGGRP
VDALRAELPANVRVAEYLPYDRLLPEIDVFVTNGGFGGVQQALAQGVPLVVAGQTEDKVE
VSARVGWTGVGVNLRTNAPKPGQVAAAVHRVLVEPTFRDRARQVGEAMRAADAWQTLDAV
LAGEATRAEADSSMHR
>A0A518H5S3|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Tautonia plasticadhaerens|TrEMBL
MKITILTVGTMGDLRPFVALAVGLKRAGHEVTVATGTDFEGFVVQHGLAYAPLRADFLEL
VKSDQGKAILRGSPLETLRAMRTTIPPLVRRILDDAWEACRGSECLIYHPKSIGGRDIAM
ALGIPAFVGLYLPMLVPTRSFPNPILPARSLGGSLNRLSYSLTRFMTLPFLGVINRWRQE
VLGLPPRSRFEDELRRDGEPIPVLYAFSPSVIEPPDDWPESVHVNGFWSLEESGYEPPSE
LASFLESGPPPVYVGFGSMASQCPEEVTRLVVEALGRSGQRGILATGWGGLGGVEASDDI
LVVDSVPHDWLFPRTAAVVHHGGAGTTAAGLGAGRPTGICPFFGDQPYWGRVVSGVGVGP
EPIPQKRLTADRLAGAIRQATGDMEMRTRAQRLGERMRSEDGVGRAVEVIERLTSQTRHE
VGSSELLA
>A0A498PUR7|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycobacterium attenuatum|TrEMBL
MRVAVVAGPDPGHSFPAMALCQRFREAGDTPTLFTGVEWLDAAHAAGIDAVELDGLTATD
DDLDAGARIHRRAAQMAVLNAPALRELAPDLVVSDVITACGGMAAELVGIPWIELNPHPL
YLPSKGLPPIGSGLAPGTGLRGQLRDAVMRALTGRSWRAGLRQRAAVRVEIGLPARDPGP
LRRLIATLPALEVPRPDWPAEAVVVGPLHFEPTDRVLAVPPGFGPVVVVAPSTAATGMTG
LAEVTLGCLTPGDTLPPGSRLVVSRLGGDDLAVPPWAVVGLGNQAELLTHADLVICGGGH
GMVAKTLLAGVPLVVVPGGGDQWEMANRVVRQGSGRLVRPLTAEALVAAVREVLSSPAYR
HAAQQAAAGIAGVADPVQVCHEAL
>A0A498PT08|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycobacterium attenuatum|TrEMBL
MSAQVATMREVGFHTAPVDAGIEAIATQDQFARNGFGVLKMSIDVLRRRASLEVDDVRGA
ISAVAPDAVIVDANCWGAISAVEASNIPWLVFSPFTPYLQSPGVPPFGPGLRPWGGTIGA
LRDASVRPVVRYLFDRPMLPRVNAIRESLGVLPVKSVDALMRRAPLLLAVGGEPFEYPHP
GWGDSVHLIGACAFEPTAMPGPDWLSAIERPLVLVSTSSIAQADVVLAATALRALAEEQL
HVVATFPAGVPRGLPRPPNATVCQFVAHGAVLDRAVCAITHGGMGTTVKALDRGVPVCVV
PFARDQAEVARRVQVAQCGTRLPARRLNPRRLRAAVRAAMTMTEGARMVATGFASTGGVV
HGAELIEQRLFGAAAGEPSAKR
>A0A1S8M824|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Clostridium roseum|TrEMBL
MSLGTVFNNKPKVFKKILSGLEKENYQVIVSAGGAYNKLIKYNFNNNILIFKRVPQLEIL
KKVDIVISHGGNNTINETLAAGKPIIVIAIGGEQGDNASKIQYLNVGKRINISNFSSNEV
LEKVKSIFADSIYKQNAERIRKIISKTDGVSTSVKLISSVAENRKI
>A0A4R8S510|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycobacteroides salmoniphilum|TrEMBL
MRVAVVAGPDPGHAFPAIALCLKFAAAGHDPVLLTGTRWLDQARSAGVESVELLGLQPRA
GDDDLDSGTKIHQRAAYMAAANVDQLRELSPDLIVSDVITACGGMAAELLGVPWVELNPH
PLYLPSKALPPLGSGLAPGVGLRGRLRDVLMRKLTQKSINEGLSQRSQARVGIGLSAKDP
GPVRRLIATLPALEVPRPDWPDEAVLVGPLHWEPTDVVLQPPSGSGPVVVIAPSTAFTGA
EGMTELALQALESAGARVVVSALNPAASGLPPWAVAGLARQDLLLAGAELAICGGGHGFL
SKALLAGVPVVVVPGGGDQWELANRVVRQGSAELVRPLNRDSLTGAVGRVLGERRYAEAA
HRAAAGAVDVEDPVRVCQDALAALK
>A0A4R8RWM0|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycobacteroides salmoniphilum|TrEMBL
MKGSAMKFVLSFYGTRGDVEPGIAVGRELLRRGHDVRMIVPPDLVAFTEATGLSAVACGP
DVRVWQDVNRDFWARFLRNFWKNFWRIRDLRELLREDWRFLVQCWEDVSSTLRSQAADAD
LLFTGVLGEESAGNVAEFYSLPFATLHVFPIRANGQLVPGMPARLGRSIMRLSEWLGWPM
FKRLEDPQRRELGLPKATGPSPWRIAERGSLEIQAYDEACMPGLAEEWAEYDGRRPFVGA
LTLDLPTDSDAEVASWIAGGEPPICFGFGSMPVESAAETLAMISAACDQLGERALVCAGG
SDFSHVPLFENVKVVGMMNYSAAFPACRAVVHHGGAGTTAASLRAGVPTLVLSTDLDQTL
WGARVKRLKVGTARRFSATTEKTLVADLRTVLDTQYVTRAREVATRMTKAAESPVTTADL
LEDFVRLKRAG
>A0A517YPB0|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Poriferisphaera corsica|TrEMBL
MNRKKRYVVMTFGSYGDVFPMLGLCEELKRRGEDVAFCSRPGTREMAERIGIEFIGAGDD
ALYEESVRNPDIWHPWKASFMVAEKIGELIDPSYAVVRNEYEKHGEDLVVIASMLVFGAR
LAREQWGFRLVTVHLQPLVFRDTRKPPRFSVYGPDMRKLPRWVNRGFYGVADLLLDGVVR
KPLNEWQVEHGIEPVKKGIFRDWGHSPDLVLGMFPEWFAEKGEEWPRVSEVVGFPVWDDE
EKAGLSAELEAFLNGGDEGGSGGDRPVVITPGSANVFGGKFIEVGVEACRKIGRRALVMT
GYPEQICELKEGREMWCEYAPFDVLFKRVSVVMHHGGVGTTARCLGSGVPQIIMPLAHDQ
PDNGQRVKELGAGDWIAPKKFTVERVAARLEEMVGDAEMKSNCENMAGQIAGEDGVKRAV
DLIVGE
>A0A165N2D9|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Rhodococcus fascians D188|TrEMBL
MWHAERVRIAVVAGPDPGHAFPAIALSLLFERAGDDPVLFTGSRWVGDARAAGIRTLPLG
GLLPRPEDDDLDAGQRIHSRAAFVATELLPDLERENVDLVVSDILTAGGGMAAERLGIPW
VELSPHPLYSPSTGLPPIGSGLAPGRGVRGRLRDTVMRALTARSIARGQQQRADARVSIG
LPARDPGPAARLIATIPALEVPRPDWPRDAHVVGPLLWEPTDELLDVPAGDTPLVMVAPS
TAFTGAEGMLEMALKGLDGTGVRVVASVLDGGPDDVPEWANAGLGRQDELLRRADVVVCG
GGHGMLAKALIHGVPVVTVPGGGDQWELANRAARQGSAVLVRPATAGAIADAVSAVLSDP
RHAAAATSAAAGAHHVEDPVSVCREVLAGSDAEGGR
>A0A5C5VL30|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Blastopirellula retiformator|TrEMBL
MNILLFPVGSYGDVHPFIGLAGELKRRNHQVTLYTSEHFRSLAERAEIDYFAVDTEEEYK
KAVYDPDIFHPLRGIGAVARNVVLPWQRRHYEIVAQALARGGDAPLVMVGSALSQGLQMA
HATFQIPLATIHLQPAVLWSNIHPPKVTGLLPTGPGMPRWWNAGLYRLAERIMIDPVLKG
PTNAFRRELGLPPIRGGITQLWHSPQRVIGMFPEWYAPPQADWPANTVLTDFPLWDESEL
GALNNDVRAFLDAGDPPIIFTPGSAMVHGHKFFEEAIAACQLLDRRGILLTRFPEQLPAQ
LPSGIRHFSFVPLSQLLPHAAALVYHGGIGTLSQACAAGIPHLIMPLSHDQPDNADRVER
LGIGATLYPSQFRARKIAEKLQHLLQSDQTNQACREISARLANPQGVTRTADEIERLLAQ
DALAET
>A0A517M435|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Rosistilla ulvae|TrEMBL
MSMVNSTQPLAIVSAFGSRGDVNPMLALARELSRRGWRILFLTSAPYQAMAEAAGFDSQA
LVSQEEFDKFIAVPGLWHPVQGLRVVLGETATMLLQPTFDLLERRVEPGNTILVTHPLDF
ASRIYRDLHPEVPLVGTVLAPMAIRTPGDPAKLTDWPLEISRPAWLVEVSYMAADWIFIS
KWLGRPVNRFRRQLGLPPIDRVLKSWYLSPDLVLGLFPEWFAPRPDQWPSQLQCTGFPLE
DAAGEMDAANIAAVQAIRDQHDQPPVVFAPGTANRQAADYFQIAADACGELDIPAILQTE
FPQQLPARLPPKVVHQSYLPFRSLLPHCRAIVHHGGIGTTSQALAAGIPQLVVPMAFDQF
DNARRVERLGCGRSLLHRQLSRRRLTQKLTDLLDGESIRSRCGEIRSRMTTNETVRQSVD
AIQQLAIARGVVGRSAETA
>A0A6J5FMZ9|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Paraburkholderia caffeinitolerans|TrEMBL
MIKTTNAGPHLRILAVCWEGGGNVPPTLAAVRALAARGHEVRLIADDTMSAEAIEAGARF
LPWKRAPNRPDRSDESCFLRDWESADPVACFQRACARIFVGPAQCYAEDILEALATEPAD
ILLGSDLLFGSMLAGEIAKLPTALLASNISLWPLPGHPPFGPGFQPARSASDRAREAEAS
AMAEQAWDGFLPRLNAARAHFGLAPLAHVHEQRLSAGRHLPATSRSFDFPAEHLPDSVRY
VGPLLEMPSWAHDRWTSQPEREMRPLVLVSFSTTNQGQADVLQRVISGLAGEPVEVVLTL
GKALEGLRLQAAANVTVLSNAAHDDILTKARAVVTHGGHGTIMRSLHHGVPLVILPMGRD
QNDNAARVDYHGAGLRLDHSVHQIIIGEAVRRVLSERCFAERAMALGRAVAKEGPGPERI
AAEIEDFVLKSSQSALSST
>A0A222TLP9|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Gordonia rubripertincta|TrEMBL
MHVALVAGSDAGHAFPAFALAERFVAAGHRATVYTGLNWSAAARRRGIDIAELPGLAATD
VDDDADAGDKLSARAARMAQLLAPVLSEAGADLVVSDVITVCGGWAAQLDGLPWIELSPH
PLYLPSRGLPPIGSGLAPGTELRGRLRDALMRAATATSIRKGERQRAAARVSIGLPAVDD
GPSARFVATLPGLEVARPDWPADTHLIGPLLWEPTDDVFDRPDGDEPLVVLAPSTADTGA
ADMVGVVLEALSERILGRRVRVVVSGLHRPSADDLARFGGDGPAPITAGLGRQDEVLAHA
RVLVCGSGHGILAKAMTAGVPVVAVPGGGDQWELANRLQRAGAGRWVRPLTVSGVAEAVR
AVLDDPGHTRCAERIGASGADTVDPVAVAERRVGLCA
>A0A6J5DNF1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Paraburkholderia solisilvae|TrEMBL
MKILIASTPASGLFNPLLAIGRILIAAGHEVTALTGSAFRQRVEGIGAKFHPLPAQVDFD
PGNIHAVAPELKNTRPGPEWLRISLERVFVDSIRGQHEGTGEVLRDLLADVIVVDDMFFG
VLPMLLGPSSERPPVIVCGTSVLHWRREDGAPVFSGLPPATTKAQFDEYATIARDYDRIV
NQPLALRLNQVLAGLGLGPVHTPLLECVVELADVDMQLSVPGFEFPRAMPATVNFVGALP
IIPNQAPRPSWAHELDGSRKVVLVTQGTVANHDFSLLVAPTLAALANERDVLVVVTAGGR
PTDAIPGPIPGNARLASYLPFEWILPKTDVFVTNGGYGSVNQAMSFSVPLVTAGLTEDKA
AVNARVAWSGVGIDLATNQPSPESLRDAIRTVLDNSEYRARASLMAEEFARIDTRSEIVR
IVAAAASRRR
>A0A5B9P7T3|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mariniblastus fucicola|TrEMBL
MRILILTVGTRGDVQPYVALAMGLIAAGHDVSICTCQIFESFVTSRGVGYLPLNDDIRDF
MESEDGRRAMETTTNLFSAIRAGIRLMPKLKGMMNRQVNEMWAAAESFQPDLILFHKKAI
GAEDFAEKLGCRCALAFYLPMYVPTRETPAFGFPRLPLGGWYNRLTYRVIEFVTRLSGGK
FVKRWRQEQGMSKKRTPYFKHADGTPIASLQAYSPSVIPEPGDWPQHATVTGYWFLDAKE
EFEPANELVQFLKNGPRPIYVGFGSIFGLDPRAKTERVIEGIRQSGCRAILAAGWGGLDL
KSFDLPDTMLAIDSAPHDWLFPRVAAVVHHGGCGTTAAGLRAGCPTIICPFFGDQPFWGR
IVHELRVGPKPIMQRKLTPENLAAAIRSTLESKSIRANAAALGEKIRNETGVDNAVNFIN
RHFQSVVLSREK
>A0A2S8BKU1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycobacterium talmoniae|TrEMBL
MRVVVIAGPDPGHSFPAIALCQRFQAAGDTATLLTGVEWLATAAAAGIDAAELAGLDPTA
ADDDADAGAKIHQRAARMAVENVDRLRALAPDLVVSDVITACGGMAAELLGIPWIELNPH
PLYLPSKGLPPIGSGLAPGTGLRGRLRDAIMRALTARSWRAGLRQRAAVRAEIGLPARDP
GPLRRLIATLPALEVPRPDWPAEAVVVGPLHFEPTEQVLPIPPGAGPLVVVAPSTALTGT
RGMAQVALDCLAPGVGLPDGARVVAVPGSTVPT
>A0A5B9QJD1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Bythopirellula goksoeyrii|TrEMBL
MRFLISALGSYGDVFPMVGLGSALRSRGHQVTLVTNPHFQAIVESVGLEFLPVGTTEEYD
ELTRHPDLWHPMKGPILVVGKSFSKSLRELYDIIAANTKAGETILVAHCLDLASRIHHDK
FGTPLASVHFAPIALRSFHQSPQMFGMLMQNWVPRSLRRFQFWLADKMVDYLVGSELNGL
RGELGLPPVRRVMHEWYFSPKLVLGLFPKWFAPPQPDWPPQTQLTGFPLWDQSGQEELQP
EVQDFLQSGSPPIVFAPGSAMTAGEKFFAAAIEACQRLDRRGILLTKYPEQLPTELPPTI
KHCHFVPMSSLLPQCAALVHHGGIGTCAQGLAAGLPHIVMPMAYDQLDNAMRLKNLGVAD
ILRPKRFTGENLGSALSRLLHDPDVQSRCSHWVQEIDVPATMSATCEALESLSAA
>A0A1V4SPN1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Ruminiclostridium hungatei|TrEMBL
MAKAVFFTLPHHGHINPNIGLLEELVRRGEAVLCYSSAKYKGIVEAAGARWREYRVDLEA
FFFKKGEYGTDIPAQENEDIRFNIQKAFEDIEALFGVGRDIYLKHCKEILEYGADYFIYD
SFAVWGKIFSDKLGIPAVCCESLFVMTEEIFNAHIEYFIVYLIKNKSLDSVTPAEKKLAA
DCMDYYSRRIQRKLAIRDFSFSGYFYSDYLNIVYLVKEMQPMSHCIGDKFALVGMDYNTG
TDLQNKREENRTPLIFISRGTIHGSEAMEVFNKCISVLGGMDCRVIISTGGCTAGTQFKD
LPSNIKVFDFVNQKQLLKEADIFITHGGLTGVREAIFNGVPMLLYPETTDQYIASRQIAQ
AGAGIWLKSKPFCCAELENAIEKILKTQEYRENVKLLKAGFESAGGYGRSVEKIFDFKKA
VNIL
>A0A1D8FX50|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces rubrolavendulae|TrEMBL
MTRVLIATTPAPGHVVGVLEVARELTRRGHEVRWYTGRAFQERVEQTGARFEPMREELDF
GGRSREEAYPHHAGLTGIAGFKAGVRDIFYRTAPGQMEDLLAVLERFPADCVLADDMCYG
ACFAAERTGIPLAWLANSVYILGSRDTGPLGRGLLPATSALGRLRNALLRFAGDHVVMRD
LRREADRTRARVNLPRLRTGAMENIARPPALYLMGTVPSFEFPRGDLHPGTHFVGGLLGL
PPERFDEPSWWGELTGGRPVVLVTQGTTANDVDGLLAPAVRALADRDVLVVVTTGSALDV
DRLHPLPDNVRLERYVPYHHLLPHVDVMVTNGGYNGVNAALAQGVPLVVAPGSEEKPDVA
ARVGWCGAGVVLPRRALTEAGLRDAVSTVLNDERYRRRAQELAEEHRSRDAPRRAAELIE
SLAEHRGQIPTGGVTR
>A0A7K0D1K4|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Nocardia macrotermitis|TrEMBL
MRVAVVAGPDPGHAFPAIALCLRLLAAGDEPVLFTGPRWLDVARATGIGVRRLKGLAPRP
QDDELDAGARIHERAAHISTEILPELGAMLPELVVSDVLTVGGGMAAERIGVPWVELSPH
PLYLPSKALPPIGSGLAPGEGWRGRARDAVLRGMTGRAIARGDRQRAAARASVGLPEQDP
GPAARLIATLPALEVPRPDWPDEAHVIGPLLWEPTTETLPLPPGDDPLVVVAPSTAQTGV
SGMASTVLEALDGVGVRVAVSTLDTPPADLPPWATAGLGRQDELLRHAAVVVGGGGHGLL
AKSLLAGVPIVTVPGGGDQWELANRAVRQGVSLLVRPFTVEAARSAVRTVLAEPSFTTAA
RAAAASAAEVDDPVEICHRVLDRARFR
>A0A0M2HFH1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Microbacterium ketosireducens|TrEMBL
MARFLFSAMPFTGHVQPVSAVAAALVARGHDVRIYTGHAFAGRVAASGARLVPWHHAPDF
DENDLAATFPRLVGKKGLGQLLVNVQDVFIKTAPAQVRDLTEEFAREPWDAVAGDDVSLG
AIFHSDLAVIPWATISVTPLNIVGTEGPPSGMGLAPGTNVFTKARDAALRALVPALSISL
RRPLIDARAAAGLPPSKATLDQTLFSPRLIVASGCRLLDYDRGDRPPHLHFVGRLTAPAA
AGAPLPLPPWWGDLAGRRVVHITQGTQNIDPSDLLQPAIEALADSDALVVAVTGVAGRDE
LPFPVPANVRVAGFIPYDALLPLTDIVITNGGWGGTLAALSHGIPLVIGGGDLDKPEIAS
RVTWAGAGVNLKTGTPTAAQVRAGHDRVVADRSFRDAAARVGAQLTALGGPAVAAELLET
LV
>A0A2H5Z0P4|4'-demethylrebeccamycin synthase|EC 4.3.3.5|bacterium HR27|TrEMBL
MVFVVEESFAGTLEAKGFEERLMRLTPPPEQPEEPGQFWKDFIANTAPHFRESTFDQITS
LVAPIWESLIDGALYVEPRLREIFAELRPDVIVEDNVVAFPAVVTAGVPWVRIISCNPLE
IPDPDLPPALSGLPTHDRSQWEAWRRAYWEAVAPLYEKLDTFCREQGAPPLPPKQFIWES
PYLNLYLYPAELDYPRSRPLAPTWHRIDSSVRDTELPFTLPDRLHDGGPLLYVSLGSLGS
AEPELMGRLVELLGRTDYRVIMSLGPQKNKLPLPDNVWGDEYLPQPSILPLVDAVITHGG
NNTTTECMHFGKPMLVLPLFWDQHDNAQRVAECDFGFRFHPYQFSDEDFFRALEDLLTNQ
ERRARLAAASARIQAADGRRRAARLISELARTKQPIHRA
>A0A0J6VPC6|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycolicibacterium chlorophenolicum|TrEMBL
MAVVLAYTSPALGHLFPFCALLTELASRGHQVHLRTLAAGVDLARELGFTAAPVHPGIEA
LQSIDPFTDSMMRSVASTVEVLTRRAVLEVGDFQVAVRDVEPDVMVLDANCWGAMAAAEA
QTRPWVVLSPFVPYLRSPGSPPFGAGAAPMRGPVGRVRDWGIGLVTVPLFDRPLARGMRP
VREALGLAPLRSADDLLRRAPGLLVATGKPFEYEHTDWGASASMIGPAAFDPPLQRPPAW
LDDIDLPVVLVTTSSVRQADEALIRATIDALDGQPVHVVATSPAGDADAVQTRRGVTMAR
FVPHSAVLERAVCVVTHGGMGVTQKALGRGIPVCAVPFGRDQFEVARRVQVARCGTRLPA
RRLSVPRLREAIGAAMTMTAGAQAVAAGFAATGGVRRGADIVESHLTRRS
>A0A7K0DJC7|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Nocardia aurantia|TrEMBL
MRVAVVAGPDPGHAFPAIALCLRLRAAGDDPVLFTGPRWFEAAEGAGIEVRRLKGLAPRA
GDDDADAGQRIHDRAAHISTEILPDLREWGPDLVVSDVLTVGGGMAAERLDIPWVELSPH
PLYLPSKGLPPIGSGLAPGVGLRGRARDAFLRRMTARAIALGDRQRAAARASIGLPEADP
GPAARLIATLPALESPRPDWPAEARLIGPLLWEPTDAVLPLPPGDDPLVMVAPSTAATGV
GSMAETVLAALDGAGVRVVVSMLDTPPVEIPPWATAGLGRQDELLRHADVVVGGGGHGLL
AKTLSAGVPIVTVPGGGDQWELANRAARQGGSVLVRPFDGPAVRNAVQRILGDPAYRRAA
GAAAATAAEVSDPVEICHRVAETVRAR
>A0A518AIM9|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Aeoliella mucimassa|TrEMBL
MHFILTAIGSYGDVHPFVGLGQRLRERGHRVQVLTNPYFSEVVESAGLELLPMLTADDYR
QLIDHAQIWHPIRGVPYLFRNAVVETMRGMFGLLEQHFVAGETILVAHPLDVASRLFRER
YQTPVALATLAPQALWSRHQPPKLGALPVGPGWPRWWNEFQFWAGTRLFLDPVLKQPISV
FRKELGLPAVARLFPGWWFSSDLNLCLFPDWFGPVQPDWPRPVEPVGFPLWDGSEVGALA
DEVEQFLGAGEPPVLFTPGTANKYAADYFTTAVEACQQLGRRAMLLTKFAEQVPSNLPDT
VGHFSFVPLLPLLPRTAAVVHHGGIGTSSQVLAAGVPQLVRPMAFDQYDNAQRLCKLGVA
EQLKPKRFSVDRVVASLARLTSSTEVAEACQMHAARCDRQGLHRAADLLEALGGKYQNLP
NGREA
>A0A518G1V2|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Aureliella helgolandensis|TrEMBL
MNIEILAVGTRGDVQPYVALGKGLLAAGHCVTLCTCAKFESFITDHGLNYASMNDDLIDF
MHSDDGKIAMENTGNWWEAIKTAFKLLPKLGPMQRQQIKDTWESTCAAKPDLILFHPKAV
GAVDFAERLGVPCMLAFYLPMYVSTGSFPAMGIPDLRIGRWYNRLTYRFIAKATWWGTGK
YINEWRQANGLPPRRGGKYLRHANGEPIPALHAYSESIIPRPSDWPESATVTGYWFLNHP
EGWRPSPELEDFLAGGEPPVYFGFGSIFGRDPVHLTQIVLDAVRATGVRAIIASGWGGLD
PARFELPSTVLAIDSVPHDWLFPRVAAVVHHGGCGTTAAGLRAGRPTVVCSFFGDQPFWG
AKVKALGVGPAAIPQKRLSVERLSAAITQATTDVTLREKADALGQRIRNEDGVGNAVQFI
NHWMKRSR
>A0A6N7CPS3|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Rhodococcus sp. T7|TrEMBL
MADIVIVTFDAGGNVPPALGIGRELRKRGHRVRVLGHQGQRPVVEAAGLEFRGYRNSPRW
PPHTEVSTWTVLTMGLTMVTDPGIGCDLREVVRDDPADLVVIDCMLFNALDAAARAGLPH
AALFHTFYAAFDGSFRHGPFGIVPRLKGLGPRRLWRQADLALVCSDPVLDPAGTRSHDGH
LVWTGAVHDAKAAAVGRTPPRVLASLSTSGFPGQRRALQNILDAAEDTDIELVVTTGPAI
DPAAFRVPANASVHRYLPHNEVMPTCSAVIGHGGHATAFRALAHGLPMLILPMSALTDQR
TIGKTVAATGAGKVLRKTAKPNQIRAALDELLASESYRTAAATLGARIRATDGASAAADQ
LLTLIDR
>A0A1V6APM2|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Deltaproteobacteria bacterium ADurb.Bin151|TrEMBL
MSTVLFLNQPTTGHLNVMLTIALQMRDEGHKVRFLIPGKKVKLDPPFQVLKDAMSLPKTI
ARHGIPVDVILPPITALIKGIRVPYTSGYKEFSLVVGLASIGTAYYVKSILKYLESIKPD
VLVSDFAFFPAHFAAELMDIPCAVIYHSGLPFKGSLIPPFASGLPIGAVPDELYRQHEQR
ERAVLRRLDEKLNRARQKFGLPPNPPDILRRPYSKWLNLVVSSQAIEAPRDNLTANTLYI
GPCFTKRKNLPDICFPFGNLKSDRFKVYVSLGTVFNNKPEVFRKIMHALDHPDYQVVISA
GGAYRKLIKRQIPNNVMLYPSVPQIDLLPNVDLVIGHGGNNSTNETLATGKPLIIMPIGG
EQTDNASRVEYLGVGLRLNIMDFNAQELRQKVEQIKNNPGFQQRASLLKEAIAQTDGCST
SSGCIQWLAYHRRPLTRPEGFPITITRENFHDLMSGVPGQRR
>A0A3R9JA12|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus mitis|TrEMBL
MKRIKIDVVVLPLSGHLFPALNLLAPLLKDSLYDIRLFTGPQRKAVAEEMGFQVLPILEN
FVDAFERVANNEGQLNLISAYRQLSASLDLINIVSDQLVQEWEKNRPDIVIADFITLSGG
LVAEQLGIPWITTMATQFAIETTAGPPCFFGGMGSPKNPFQSAQQWLGRKVTRLGKRIVT
FLLRERLKRYDFKLYNQKNQETIYSPYSILGIGMKELELKSGFPEHYLWVGPFGSSIERA
ENYPLDLSPYASYKKVLVSCGTQLAWAKDNLLYQTQQLAKAHPDCHFFVTLGFGGQDFQC
EELMDNVSVVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIYGKPALILPHDYDQYDYAVRG
LEAGIALTTKREDTEAIGRAFDELLARDGWSDLNKLSRVAQDYQPTEILKNEIYRLLGGQ
GEIKHEESIGNRCYGLFR
>A0A143QD11|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Rhodococcus sp. PBTS 1|TrEMBL
MTAILLCATPLAGHVGPLTTLGADLRRHGYEVHLLTGSRFATSVDAAGLHHHSLSGAADF
DERDPSTFVPHADRYTGLALSRYQVEQTFVRPIPDQAAAVERLVGDHHVDAVLTDGTFAG
ALPLLSVPAHRRPPVLGVGVMPLVLVYDRSMTTAVCIGGNDVSWVEPAALA
>A0A3R9JRG9|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus oralis|TrEMBL
MRKIKIDVVVVPLSGHLFPTLNLLAPLLKDPLYEIRLFTGPQRKTVAEEMGFRVIPILEN
CVDEFERVANNEGQLTLFSAYRQLSASLDLINVVSDQLVQEWQQNRPDIVIADFITLSGG
LVAEQLNIPWITTMATQFAIETTDGPPCFFGGMGSPKTSFQSIQQWLGRKGTRLGKRIVT
FLLRERLKRYDFKLYNKKDQETIYSPYSILGIGMKELELKSGFPEHYLWVGPFGSSIERA
ENYPLDLSPYAGYKKVLVSCGTQLAWAKDNLLYQTQQLAEAHPDCHFFVTLGFGGQDFQC
EELMDNVSVVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIYGKPALILPHDYDQYDYAVRG
LEAGIALTAKREDTEAIGLAFDELLARDDWADLNKLSRAAQIYQPTEILKSEIYRLLGDK
EK
>A0A1A8TVI4|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Marinomonas spartinae|TrEMBL
MQIVILTIGTEGDVRPLVALAVGLKKLGHQVRIATDMSCQSPVVDHGLEFSPLTGDFMDW
MRRDKDLQKRGLSTLAMAKAFQAQLLEMSQDWPEQGRQAAQDTDLLIGNGMVYFLAQSLG
EAFGIPVVETQLVPTMPSHHAPIMPLPGWMKSLPPAINVGLGHLTRQIVWHVYQPVYNKV
VRPQLGLAAYPRFGPYHHKKFQRPKMFAYSPCLIEPRKNWPSRIQTTGPWMLETGAAWEP
PSELLDFLQAGPKPIYIGFGSMFHHDAQAFTDMIQASIEETGQRVIIATGWGGLHVKNMS
EASRDKMLSVGHIPHDWLFPRIALAVHHGGAGTTHAVLRAGIPSVVVPVFGDQPFWAQRL
ERLGVAPRALPRETLTSSDLTKAITVAASTEMRARASTVARMMQAENGVDNAIKALRDFG
LLPA
>A0A7M4DMD8|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Occultella aeris|TrEMBL
MPLAYLFALVDGGGTVPPELGVARRLIGRGHRVRVLGEDSMAADVAATGATFVPWRHAPN
RPDRSVAHTAYRDWETSDPLALARGMADHMIAGPASGQARDVAAAIEADRPDLVLASFTA
LGAMIGAEAEGVPFDVLLPNVYTMPAPGMPPMGLGLRPATGRPGLLRDRAVNAMSTRLLG
RYGLDRVNAARAAHGLAPVATIWDQVHRARRELVMTSPEFDFPATVPANVRYVGPVLDDP
PWAGGDRTPPPGEEPLVLVAMSSTFQDQTGCLQRVTDALGTLSVRGLVTTGPALDPALIH
ASPNVRVVAAAPHAQVFPVAAAVVTHGGHGTVIKALAAGLPTVVLPHGRDQADNAVRITA
RGAGITISRDSSTPVIARAINRVLSDPAFARAARTLGAAVAADAAGDALIRELENLEDAT
RAES
>A0A0H2MKK5|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Variovorax paradoxus|TrEMBL
MKIAVLTYGTEGDARPLAALCRALDEAGHSSVLLADASTLGAAQRLGVRTQALAGDIRGA
LGASGAIANVVAHSERPGAAAKALAAIANGNATAWLRQAVETARGSDAIVCAGLAAFVGL
SAAEALRVPAIGAGLFPLTPTRDFASPFLPPSRVPRWLHRASHHLVNAMLWRAFRPAVNA
ARAEVCALPPRRRMWSTHPMLYGFSPSLVPRPADWPANAAVCGQWIPPAPDWQPPPALAA
FLAAGEAPVYIGFGSMTGFDAARLRQVVVDGVAGRRAVLHPGWSGIDTQGLPTNFHVVGE
VPHDWLFPRTSLVVHHGGSGTTHSAARAGVPSVAVPFAGDQFFWAHQLAQAGVAPDAVAG
SRLGADDLARGLAFAGRPEVRARAQALGEKMRAEDGLSRAVEAIERSLAGRALRL
>A0A1B8YGE8|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Photorhabdus namnaonensis|TrEMBL
MARIVIAAVATPGHVYPMLKVTQSLIAQGHQVTVFTGALFRQQVEDLNATFIPFDEQIDF
DYRHLKQRFPDRAHLPPGNLQMALAFKDFFCTPIPFLDRQLQQIIHEQQAELLIAENCFY
GILPLLQKEKTHRLPVIIIGITPLAYSSKDSIFWGPRIPPALLPSELTHEQLVDEETRKL
ITEVQDNFNDALAQSGCATLTRFFNDEVILGSDRFLQLSTLAFEYPREGLPDTVHFIGPL
PNPAPTTESPQLWEENDPRPLVIVTQGTMSNTDLNQLIFPTLRALATLPVRVLATTGGSS
IEIRSENIPDNAHIEEFISFEHWLPKASLLISNGGYGTINYALNHGTPVLIADTGEGKQE
TAFRVVWAGCGINLDTAQPTEFQLKQTVENMLRTNLFKQRAQIVQDDYASHDALAAISHH
AEQLIFENRAN
>A0A4R8SI64|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycobacteroides salmoniphilum|TrEMBL
MKFVLASYGTRGDIEPCVAVARELLRRGHEVQMAVPPDLIAFVEAAGPTAVPYGPDLQAV
LDAHRDFWTHFFRNFWKIRDLIRMRRDVVRPFLQCWKDIVATLTSLAEGADLLFTGVNFE
DAAGNVAEYYDIPLATLHFFPLRANGHFVPLLPAPLGRSTMRVGEWLAWQNAKKVEGVQR
GELALPKAAAPSPWRITERGSLEIQAYDEVCFPGLAAEWAEHEGRRPFVGALTLDLPTEF
DDEVASWISAGAPPVFFGFGSLPVESAAKTLAMINSACDQLGERALVCSAGSDFSDFALA
ENIKVVDAMNYSAAFPACRAVVHHGGTGTTAAGLRAGVPTLILSTDLDQTLWGARVKRLK
VGTSRRFSATTEKTLVADLRTILEPECAARAHEVATRMITAAESVVITADLVESLAAG
>A0A3R9K570|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus oralis|TrEMBL
MLERTIILVVLFLKICYSRHMRKIKIDVVVVPLSGHLFPTLNLLAPLLKDSLYEIRLFTG
PQRKAVAEEMGFQVIPILEHCVDEFERVANNEGQLNLISAYRQLSASLDLINVVSDQLVQ
EWQENRPDIVIADFITLSGGLVAEQLGIPWITTMATQFAIETTDGPPCFFGGLGSPKTSF
QSVQQWLGRKVTRLGKRIVTFLLRERLKRYDFKLYNQKGQETIYSPYSILGIGMKELELK
SGFPEHYLWVGPFGSSIERAENYPLDLSPYAGYKKVLVSCGTQLAWAKDNLLYQTQQLAE
AHPDCHFFVTLGFGGQDFQCEELMDNVSVVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIY
GKPALILPHDYDQYDYAVRGLETGIALTAKREDREAIGRAFDELLARDDWPDLNKLSRAA
QIYHPTEILKSEIHRLLGDKEK
>A0A4V3HU70|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycobacteroides franklinii|TrEMBL
MKFVLASYGTRGDIEPCVAVGRELMRRGHDVCMAVPPDLIGFVEAAGLTAAPYGPDLQNV
LDAHREFWTHFFRNFWKIRDLIKKRREVVEPFLQCWKDIVATLTSLADGADLLFTGVNFE
DAAGNVAEYYDIPLATLHFFPLRSNGQFVPLLPAPLGRSAMKAGEWLAWQNAKKVERVQR
GELALPKAAQPSPWRIAERGALEIQAYDEICFPGLAAEWAEFAPRRPFVGALTLDLPTDF
DAEVASWISAGTPPIFFGFGSLPVASAEKTLAMISAACEELGERALVCAAGSDFGGTTYS
GNIKIVSAMNYSAAFPECRAVVHHGGTGTTAAGFRAGVPTLILSTDLDQTLWGARVKRLK
VGTARRFSGTTEKTLVSDLRVILDPQCVARARELAARMTEPTESVETTADLVEDLAASYR
CGSRS
>A0A0J6YXI2|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycolicibacterium chubuense|TrEMBL
MASIIIGSVPVHGHVTPLLAVAAHLVARGDDVRFVTGSRFADKVAATGARFVPLPPEADY
DDRDLTRSFPQRARLKGARAIAFDIEHVFARPAREQYGALVAALAERPADAVLVEPAFVG
AAFLLHRPRPERPAVVVCGVLPLCVESRDTAPFGMGLAPARILNRPRNAVLAGVNRRVLR
RPYAVIDALHRDLHGVDMPGTMIDWGRRADALVQFTVPGFEYPRSDAPEALHFAGPLSAT
GSQAPLPQWWSELDGSRPVVHVTQGTLANLDYEQLIAPTLRALADEDVLVAVTTGGRPLD
TLPDLPANARAAIYLPYDELLPRTSVFVTNGGYGGVQYALRFGVPIVATGGKEDKPEVGA
RVAWSGVGRRIRSEHPSARVLRREILAVLHDGRYRQASARLAAQMAAAPGFTGLADVIDG
LTERKTRTCANP
>A0A1E7WPN3|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Duganella phyllosphaerae|TrEMBL
MSASSVPSRSLQPATAQSPLARPAAVQPRILILAVGSAGDVYPFIVIGQALRARGFEVTL
MASANFEERVQRAGLQFISGLSQQELDAGIRDPDLWDPVKGFATIWKHMARHLPAAYSQQ
LALVREKPTLIVASTLGLTGRLLQEAHGVPLVTVHLAPSCLFSADDTAVRRGLHWPRGWP
RWAVRLTLGLVDRLMVDAVVRPALNGLRANIGLAPVRRVMSEWLHSPQQVVCAWPAWFAA
PQADWPPNAVCAGFPRMPAPTAELDPALQRFIDDGEAPIVITPGSAMAHGSDFIARALAA
AMALELRAVVVTPYREQVPADLPATVHYAAYAPFDVLSRQAAAFVHHGGIGTSATVLAAG
KPQLIVPFAFDQPDNAARLTRLGVAATVLPDSAPAVWQQQLGGLLEDPAVAKACATFATV
MASGPAAADTIAELVLGTVSLS
>A0A896WMV7|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces cyanogenus|TrEMBL
MPVPSVDKPARKVPRMSSSSRPILFVSLPESGLFNPVQTIAGEFARRGVQDLWFATDEER
RGDIEALADVSTVRFASLGDVVPELSALTWDEEVYAKVTGPKRFAAHAAVIRHTYDPALH
VDKYRRLLEIVEKLEPALMVIESLTAYAIDIAITRRIPYVLVSPFLPSNYVTAYTPFTKA
YTDPDFPVPHSGLSVHMTLRQRIENRLFRVRTLGIFLRPSMARVLKRDRRTRQQLGIAPE
ARRFLARIEHAELVVNGSLAELDYPFRAPDNMRMVGALIPPLPQAPEDEDVSGWLATHNS
VIFVGLGTTTRLTSEQVRDMLTVARRLGNDHHILWKLPVEQQRLLPDEPLPENVRIESWV
PSQLDVLAHPNVKAFLTHGGGNGFHEGLYFGKPMVIRPLWVDCYDQAVRGEDFGVSLTVD
PHRGTGDDIFRALRRVLDEPSFSERAQHFGKVLRAAGGAAAATDLVLDLPALAS
>A0A3R9KM14|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus mitis|TrEMBL
MKRIKIDVVVLPLSGHLFPALNLLAPLLKDPLYDIRLFTGPQRKAVAEEMGFQVLPILEN
FVDEFERVANNEGQLNLISAYRQLSTSLDLINVVSDQLIQEWEKNRPDIVIADFITLSGG
LVAEQLGIPWITTMATQFAIETTDGPPCFFGGMGSPKNPFQSAQQWLGRKGTRLGKRIVT
FLLRERLKRYDFKLYNQKNQETIYSPYSILGIGMKELELKSGFPEHYLWVGPFGSSIERA
ENYPLDLSPYASYKKVLVSCGTQLAWAKDNLLYQTQQLAKAHPDCYFFVTLGFGGQDFQC
EELMDNVSVVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIYGKPALILPHDYDQYDYAVRG
LEAGIALTAKREDTEAIGRAFDELLARDGWSDLNKLSRVAQDYQPTEILKNEIYRLLGG
>A0A508TYQ7|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Bradyrhizobium ivorense|TrEMBL
MKILVASVPAPGHVNPMLAITRILKADGHEVAFHTGASFEARVAASGARFLPLPADADFD
PGNPFERAPELKTVPPGFKWLRIALERFFIDNIAAQHHGVQDVLKKFPADVILGDDMFFG
LLPMLLGPRLKRPPIALCGTSLLHWPREDGAPNFLGLPPATTIEERDEYLALARDYDEAV
DRPAGRHLNKALKALGVGPLAMPLFDSSVGLADAYMQLSVPGFEFPREIPPSVHFVGTPP
IIPGQVDLPPWAHELDGSRKVVLVTQGTVANHNLDLLITPTLAALANERDVLVVATTGGR
PTDDISGPVPANARLSSYLPFEWLLPKVDVLVTNGGYGSVNQAMSFGIPLVGAGLTEDKA
DVNARIAWSGVGINLADNAPTKQALRNAVRTVLDQPNYRQRAAQMKDEYAAIDTPSEILR
IVGQLVADQSTSLRSAPMAAGKARRAARQH
>A0A142YA85|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Planctomyces sp. SH-PL62|TrEMBL
MARYLFTVWPFVGHINPFMSVARALKARGHDVAFYTSESTRAVIEPQGVTLFPFNHLREE
PIWEAVQAAETRATLGWHSPRLLLRAFRDWLAGTLPEQVADIQEIVDEWRPDVIVTETGM
WGPIVVLGETSPVPVAILTTLMGCLIPGPDAPPGGPGLPSPRNFRTRLLAKAVTKLGDVL
AIGVRRHVNKVRASHGLAPMESSVNAHMARLPLYLIPSVREIDYDRHDLPPSVHYVGPCV
WNKSEDAPAPAWLDELPTDRPWVHVTEGTAHFQDPVVLRAAARGLADLPMQVILTTGSQR
DPAELDLGPIAPNIRVERWVSHSDLLPRCSVLVTTGGAGTVLTALQLGVPLIIVPTHWDK
PDNARRVVEAGAGLRLTPRRCTPDGLRAAVERVLNEPSFRRNARRIAGVMAEHPGPAGAA
VLLETLAARSPNAGRPAKTLVH
>A0A1X1PK66|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Burkholderia puraquae|TrEMBL
MKRILFCVVPEKGHVNPCIGPAQHLRAAGCDVAFYAPADISAQLDGAGGFTFVGPRETPE
RHDLSRGASFAANIRDADWLRHWIRTLLIDLAPAQVDGIRAVLRDWRPDVVVIDPLLYAA
AIAAELEGLPWVAMSNSLNPVLPGDLDSELLRTVRWLEPERTRLFARYGLDARFRGCDIL
SPHLTLAFTTDALVGAPPPGVELVGPALPSGPRGDETPFPWERLDADRPLVYMSLGSQLY
YHPDVFAKVIDAARATSAQLVLSVGELVDSDELPADDERVVAVRYVPQLALLRRTHAFVS
HGGANSVMESLACGVPMLLSPFCNDQFHSAHFVERAGAGCVLDLQRAGVAEIADALERLL
RPGPLREQAARIRASYAARDGSAEAARLISALASGNRLATAS
>A0A0J6YTB7|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycolicibacterium obuense|TrEMBL
MRVAVVAGPDPGHAFPAIALCRRFLAAGDEPTLLTGTRWLDTARGEGFDAVELDGLRVMA
GDDDADAGAKIHERAARMAVLNRARIESLKPDVVVSDSITTCGGLVADLIGVPWIELNTH
PLYRPSKGLPPLGSGLAPGVGLRGRARDAVLRALSARSWRAGLRQRAAVRVEIGLPAADP
GPLRRLIATLPALEVPRPDWPAEAVVVGPLHFEPTTTVLDLPPGDGPVVMVAPSTASTGA
VALADLALQTLIPGQVLPQGARVAVSQLHGPDGEVPPWAVVGLGRQDELLSRADLLVCGA
GHGIVSKALLAGVPMVVVPGGGDQWEIANRLVRQGSAQLVRPLNSETLGTATAEVLGSAR
HRDAALRAGATADAVADPVGVCHDALRASA
>A0A853SIF9|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Janthinobacterium lividum|TrEMBL
MLAAPDASLGLFPAWFAAPQADWPPHFAQADFTGAAMHGAAALPPELERFLDEGEPPIVF
TPGTGHQHAQRYFSIALAVLRRLGRRGLFLTPHAAQLPQRMPASVMWQAHAPFAALLPRV
AAVVHHGGIGTSADAFRAGIPQLIVPFAYDQFDNGWRAKRLGVGDVLLARRLSAGSMQRQ
LARLLAAPEVKLACGEVARQMGQGLESARLLDHVEAALAA
>A0A0M2HU18|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Microbacterium hydrocarbonoxydans|TrEMBL
MPSTSYRADGPLSLLICSTPVHGHVVPLLAVARTLVAQGHEVRFLTGARYRSAVEGTGAR
WVGLPREADYDDSDMDRAFPERSGRRGVDGARWDLEHIFLAPAPAQLSAIDEQLRAAPVD
AVLVESLFLRGMLLLCRPAAQRPPVLNLGIVPLGLRSRDTAPFALGIPPMRGPLGTLRNR
ILNAVTDRLVFGELQTAAERMVSEVVGARLPTGAMNYPSLADAIVQFTVPAFEYPRRDLT
VPVHFVGPVSLASASDTSEPDWWGDLEGSTVVHVTQGTVANADLEELVLPTMRALADEDL
LVVASTGGRPVPSAALPANARIAPYLPYDRLFAHTDAVVTNGGYGGVHFALAQGVPVIAA
GNTEDKAEVSARVAWSGAGVRLRPGRGGLPARAIRSAVRRVLDDPAFRDHAARIGAEIAV
APGPAGIEAVVRGLLAARVG
>A0A1V5L3M6|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Verrucomicrobia bacterium ADurb.Bin474|TrEMBL
MKILFKIYPQRSHYNGTFPIAGALARMGHEVAYVGIESLRAHVEAQGFRYIVQDDDIYPH
AEAQPLAGSELTSFRDKVAAWMQFRNWAKARWRRCSALDEVIHRIPFDFLMLDSPYSFFA
LALCRDQKRFGIIESMMPQDQSVGCPPLSSTYIPRGTWWSDRICDGLWVRYLLKRWFLGA
SGMRPDYDKRLIRRTASKMGVSPSDLDIRRYFHIGFRNAPEFVISPHCLDFPRAATPNRV
HLSIRVNPDRPESQWDYGFTSRFESMVARRPGIPLVYCSLGTAGWRYKGATGFLGNVIES
AKGSPWNLIVSIGNLDRSMLPSPPPNVAVLQSVPQMRVLKSCDLMITHGGMNSITECVAL
GVPILVCPGTHQIDQAGNAARVVYHGIGLLGNLRRETTESLKHKISQILGNPAFRDQCLR
VKQRMDSSPELEAILSHYFGDTTEAYRASESAQLVQEGRKERSSLPKKTFDATSSLTWLD
GSRVEN
>A0A0J6W5S2|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycolicibacterium chubuense|TrEMBL
MAVVLAYTSPALGHLFPFCALLTELASRGHQVHLRTLAAGVDLAGELGFTAAPVHPGIEA
LQSIDPFTDSMMRSVASTVEVLTRRAVLEVGDFQAAVRDVEPDVMVLDANCWGAMAAAEA
QTRPWVVLSPFVPYLRSPGSPPFGAGAAPMRGPVGRVRDWGIGLVTGPLLDRPLARGMRP
VREALGLAPVRSADDLLRRAPGLLVATGKPFEYEHTNWGASVSMIGPASFDPSLQRPPSW
LDDIDQPVVLVTTSSVHQADEALIRATIDALDGRPVHVVATSPAGDTDAVRTRRGVTLAR
FVPHSAVLDRAVCVVTHGGMGVTQKALGRGIPVCAVPFGRDQFEVARRVQVARCGTRLPA
RRLSVPRLRKAIGAAMTMTAGAQAVAAGFAATGGVRRGADIVVSHLA
>A0A653LGZ1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Curtobacterium sp. 8I-2|TrEMBL
MSSYLLCSPPVYGHLAPLVDVGRALAVRGHDITVLTGTKYRELVVGVGLRFAALPADVDF
DDADLQERLADASAARGIAVVREGIIAMFVRAIPSQYRELTALLAAGRFDAVLGEASFTG
LAPYLALPPAERLPVLGIATTPVTLTSVDAAPFGTALPPGRGPVARARNRLLTAALHPVL
TRPLRRAVDAVLAEVGAPPSTIDTFDFAYRAFDTLFQMSVRELEYPRRELPDTVRFVGPV
VARSAPTSAADLPAWWDDLDTDTPVVLVTQGTIDTVDLGRLLAPTLRALADEDVLVVATT
GGRPVDQLERALGTALPANARVATFLPYDQLLPRCSVVVTNGGFGGVQRTLAHGVPLVVA
GSTEDKPEVAARVAWAGCGRNLRSGTPRPRAIRRAVLEVLSTSTHRARSRQVAASIAALP
DPVDVIETGLAAAVAAATAGGTQRR
>A0A6C0QCW3|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces sp. S4.7|TrEMBL
MTRFLLVVPPLVGHTNPLAAVAGELLHRGHEVAWAGYGEQIRALAGPRAEVFECAMPDAG
LSRPPGLKGPAAFQHLWEKFFIPLGDLMAPGVDAAIDAFRPDAVFTDQHAVAGALVAERR
GIVHVTSATTSAELVDPLADLPKVGAWLDELLGGLRARVGDPSASGDPRFSPHGVIAFTG
RELVGDTPLPSEHVHLVGPAVAPRAGSSDFPWERLDPARRLVLVSLGTANADAGGRFLNE
AVTALDALGDRVQGVVVDPGRTLGAVPPGVIVRPHVPQLELLARADAVVCHAGHNTVCET
LWHGLPLVLAPIRDDQPIVAGQVVDAGAGVRVRFRRVDAARLGAAIETVLEDTGGHRAVA
ESIGRSLRAAGGRSAAADHLERIAARHAPVPASG
>A0A1S8L1D4|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Clostridium felsineum DSM 794|TrEMBL
MSKIMFVTQPTMGHTNAILSIAVRLKELGHEVLFVIPNAKRIPKKIINRLPDYVKTSLSI
PGKVRANGINCVSIDMPIKVLFKYMILPFAKRFTETQYAMNVFSDCLYKYSKLIEGIVLR
EKPDVIVNDFFFFPPYIVAERYDIPCVTIYHSGLPFRGDGIPPFGSGLAINGNWGVKGKL
YAILSRNTNKLVTKRYIRACKKMDVSDIRKVNWSKPYSKWLNLLLTAKEIEAPRQLNNNN
TIFVGPCFSCKRIDIQDKFPFEILSEEIPKIYVSLGTVFNNKPKVFKKILSGLEKENYQV
IVSAGGAYNKLIKYNFNNNILIFKRVPQLEILKKVDIVISHGGNNTINETLAAGKPIIVM
PIGGEQGDNASKIQYLNVGKRINISNFSSNEVLEKVKSIFADSIYKQNAERIRKIISKTD
GVSTSVKLISSVAENRKI
>A0A1E3X2H6|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Candidatus Scalindua rubra|TrEMBL
MRITILTAGSRGDVQPFMALGAAFKAGGHNVLIATHNTFENAIRDLDLEFSPLKGDIREL
LQSKPVQEILTAGGNPISFVPRFIRASKPLVIETVKGMLTACENADLIVLAGLGFYGGAD
VAEALKIISVTAAVQPMQPTRGFHNPFFPAPLRWMPFKKAYNRLSHVLFAKFFWQFVRPL
LNKARKEILDLSPTTRQPVFKQVDKQQILSLWGISPTVVPKPEDWAEWHKVTGYWFLDAP
SKWQPPEDLADFLNTGDSPVYIGFGSMNDEDAESLTEIAIQALKMAKRRGILLTGWGAIA
TASQSDDIYMADSIPHDWLFPRVAAVAHHGGAGTTAAGFRAGVPTVVIPFAADQFFWADR
VVKLGVGVTPGYRKKLTIEKLSQSLQTVLADENIRLRAKKLGEKVRQEDGLKQSVKEVEA
LLPNPASER
>A0A143Q8S8|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Rhodococcus sp. PBTS 1|TrEMBL
MRVVLIAGPDAGHAFPVMALAERFRSAGDEAVVLTGERWWQAGRAARLDVRPLPGLEPRP
EDDDADAGQRIHGRAAHMSTQVMPVLTDLAPDLVVADVLTAGGGMAAERCGIPWVELSPH
PLYRPSRSLPPLGSGLAPGSGVRGRMRDGVMRRLTARSVRAGTAQRSAARISVGLPALDP
GPARRLIATIPALEVPRADWPSEARLVGALLWEPTDTVLDLPSGDEPLVVVAPSTAATGE
ASTVDVALSAAARSRASGLPVRVAISALEVPGRQHDALPSWAVAGSGRQDVLLRSASAVV
CGGGHGMLAKTLSSGVPAVTVPGGGDQWELANRAARQGSSIPVSPPDVDALARALARVLR
EPSFRRAARRAAAGADAVRDPVAVCRSVLAGRA
>A0A4V3HXT8|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycobacteroides salmoniphilum|TrEMBL
MKFVLASYGTRGDIEPCVAVARELLRRGHEVQMAVPPDLIAFVEAAGPTAVPYGPDLQAV
LDAHRDFWTHFFRNFWKVRDLIRMRRDVVRPFLQCWKDIVATLTSLAEGADLLFTGVNFE
DAAGNVAEYYDIPLATLHFFPLRANGHFVPLLPAPLGRLTMKVGEWLAWQNAKKVEGVQR
GELALPKAAAPSPWRITERGSLEIQAYDEVCFPGLAAEWAEHEGRRPFVGALTLDLPTEF
DDEVASWISAGAPPVFFGFGSLPVESAAKTLAMINSACDQLGERALVCSAGSDFSDFPLA
ENIKVVDAMNYSAAFPACRAVVHHGGTGTTAAGLRAGVPTLILSTDLDQTLWGARVKRLK
VGTARRFSATTEKTLVADLRTILEPECVARAHEVATRMITAAESVVITADLVESLAAG
>A0A518JXD9|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Rosistilla carotiformis|TrEMBL
MTDAASKQPLAIVSAFGSRGDVNPMLALARELHRRGWRILFLTSAPYQALAEAAGFDSQS
LVSQEEFDAFIAKPGLWQPVQGLRVVLGETATMLLQPTFDLLQHRVEPGNTILVTHPLDM
ASRIYRDLHPEVPLIGTVLAPMAIRTPHDPAKLTDWPLEISRPAWLVEASYLAADWVFIR
KWLGRPVNRFRRQVGLPPIQRVLKSWYLSPDLVLGLFPDWFASHPDHWPSQLQCTGFPLE
DAAGEMASANVAAAEAIREQHAQPPVIFAPGTANRQASEYFQIATDACQTLNIPAILLTE
FPQQLPDRLPENVVHQSYLPFRALLPHCRAIVHHGGIGTTSQALAAGTPQLIVPMAFDQF
DNARRVERLGCGRSLLHRKLSRRRLTQQLADLLNDDSIRARCHELRDRMTTSNTVGQSVD
AIEQLAATRGVLPRHTAAN
>A0A428C340|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus oralis|TrEMBL
MRKIKIDVVVVPLSGHLFPTLNLLAPLLKDPLYEIRLFTGPQRKTVAEEMGFRVIPILEN
CVDEFERVANNEGQLNLFSAYRQLSASLDLINVVSDQLVQEWQENRPDIVIADFITLSGG
LVAEQLNIPWITTMATQFAIETTDGPPCFFGGMGSPKTSFQSGLQWLGRKGTRLGKRIVS
FLLRERLKRYDFKPYNQKGQETIYSPYSILGIGMKELELKSDFPEHYLWVGPFGSSIERA
ENYPLDLSPYAGYKKVLVSCGTQLAWAKDNLLYQTQQLAEAHPDCHFFVTLGFGGQDFQC
EELMDNVSVVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIYGKPALILPHDYDQYDYAVRG
LEAGIALTAKREDTEAIGRAFDELLARDDWPDLNKLSRAAQIYQPTEILKSEIHRLLGDK
EK
>A0A3R9JDS0|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus oralis|TrEMBL
MRKIKIDVVVVPLSGHLFPTLNLLAPLLKDSLYEIRLFTGPQRKAVAEEMGFQVIPILEN
CVDEFERVANNEGQLNLFSAYRQLSASLDLINVVSDQLVQEWQENRPDIVIADFITLSGG
LVAEQLNIPWITTMATQFAIETTDGPPCFFGGMGSPKTSFQSAQQWLGRKGTRLGKRIVS
FLLGERLKRYDFKLYNQKGQETIYSPYSILGIGMKELELKSGFPEHYLWVGPFGSSIERA
ENYPLDLSPYAGYKKVLVSCGTQLAWAKDNLLYQTQQLAEAHPECHFFVTLGFGGQDFQC
EELMDNVSVVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIYGKPALILPHDYDQYDYAVRG
LEVGIALTAKREDTEAIGRAFDELLARDDWADLNKLSRAAQIYQPTEILKSEIHRLLGDK
EK
>A0A6N7CPJ2|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Rhodococcus sp. T7|TrEMBL
MFTDPGPGIDLLDTVAAEPADVVVTDCLLYGALAAAERARLPRVTLVHTFYEFMEAGARR
GPAPVLARLKGQRPLRLWTSSDLVLVTTERELDPAGRRRRDLPPAVHYTGVVPHRMPSAL
TWVGEREPLILVSLSSTNFRGQQQTLQRVLDALRGVPARTVVTTGTSVDPTTLTAGPDAE
IHGHLDHETILPDATLVIGHGGHDTTMRALAHDVPLIILPMHPLLDQTMIGRTLDHRGAA
RCLPKKAPPDRIRAAVDTLLADGPHRAAAAGLGTRIRSHDGSMAAADLIDHLPHRQVRR
>A0A653YQ97|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Arthrobacter sp. 9AX|TrEMBL
MKILFASQAIDGHFNPMTGVAMELKERGHDVRWYTGRVLAGKLGELGIPLFPFKRAIEHR
ADNLTELYPERARLKGPRAIGFDGEKIFASNISSFFEDIRELDHDFPFDVLVADSSMFIH
RLVAHLLGKRVVGFVVIPNMESDPLVPPLFFGFSPARNPGEKALQAVAGLLSDKVILRAA
SQSYRRQHRFYGQEMPKGGRLTDEPYRCSDAVIQTGSRSLDFPRRNDNPKVHYVGALLPY
RPPGTAVPEIRPEGFARTVVVTQGTVDNLDQDKLIIPALEALKDTDTLVMVATAGRGTAE
LRERYPQPNIRIHDYIDFEAVFDFTDVFVTNGGFGGVQLALSKGVPLVVSGINEGKNDVN
ARVEYAGAGINLKTDRPSAAGIGKAVNAILAHPEWKHRAQQMAQDFGSQNPAEAAAKVVE
GVLSNS
>A0A0F3HKF5|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus infantis|TrEMBL
MKKIKIDVVALPLSGHLYPTLNLLAPLLQNPQYEIRLLTGPQKKAVAEAVGFQVLPILEG
HVKEFEKAANNKEQLGIISAYRQLSASLDLVNLVSDQLIQEWTNHRPDIVIVDFITLSGG
LVAEQMGIPWITTMATQFAIETTDGPPCFFGGMGTPQNCWQVLAQFLGRKTTRLGKRIVS
LLLRDRLRRYHFKLYNQKGQETIYSPYSILGIGMKEVELKKGFPEHYRWVGPFGASVEAG
EDYPLDLSVFPNRKKVLVTCGTQLAWAKDNLIFQAKQLAKAHPDFHFFVTRGVGGEPFQC
ENLMENLSLVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIYGKPALILPHDYDQYDYAVRG
VEAGVAFTAKRDNSQEIGQAFEKLIAKEDWSELEILRQAAQSYHPTEILESEIHRLLADK
EKE
>A0A1J5QVD3|4'-demethylrebeccamycin synthase|EC 4.3.3.5|mine drainage metagenome|TrEMBL
MANILIVGKGGFGDLFPLFAIAEELIRRGHAVRVAAEPHHAAACAQIGAAHRVLDSAAPP
RAGSLRAQLAATLDPSALATEVRTLEPLARGADLMLGNQLAYAGAIVRDLLGTPWAFCAA
SPLALPSRFDAPLWPYLHPLQRAAAAIGLPQAAFIGPARAATRALMRAQTRLRRELGVDT
HAHPRFEALYSQRLNLLPVSPLLLQPQPDWPAHTRLSGFAWFESTFLGDQRLADELAAFA
AAGAPPVVLAPGGSARGDPLRFLERGVAACRAVGRRAIVVAAPRLHAALPAGDDVRPTGY
LPYARLFGLGAAVLHSGGIGTLGWAMRAGVPSLLLPGDWDQYDNARLAQRAGVGAVLGKR
ADTACDAAVLDALLGDDALHQRLRRLAPQVAAENGAAVACDAIEAII
>A0A1Y2NDB5|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces platensis|TrEMBL
MRVLFVVPPLAGHVNPTVAVAAELTARGHQVAWTGPAAALTPLLPTGSLLYPAGDRGAAG
GQELGGARWRDLRGIAALRFLWAEALIPLARAMLPGVHAAVEAFRPDILVTDQQALAGPV
VARRHGLPWATSATTSAEIVRPFDDFPKVGEWVNRRIAALLAECGAPGGWDPRFSPHLVL
VFSTPALIGDDGPERSAAHTLNGGPGGVAGRYPPHYVFVGPAFGARPPGGDFPWRRLDPG
RARVLVSLGTLNRAAGARFYPAVLRAADALADRAQLILAAPGDLAGDIPPHMLHQEYVPQ
LQLLPHLDAVLCHGGHNTVCEALAYGLPLVVAPVRDDQPIVARQVAEAGAGVRVRFGRAR
ADELHQALSAVLDDPAHRRAARRIQASFAAAGGAATAADRLEKLRPGPRPGPSAPATAPT
DNEKGP
>A0A428EEW1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus mitis|TrEMBL
MLERTIILVVLFLKICYSRHMRKIKIDVVVVPLSGHLFPTLNLLAPLLKDPLYEIRLFTG
PQRKTVAEEMGFRVIPILENCVDEFERVANNEGQLNLFSTYRQLSASLDLINVVSDQLVQ
EWQENRPDIVIADFITLSGGLVAEQLNIPWITTMATQFAIETTDGPPCFFGGMGIPKTSF
QSIQQWLGRKGTRLGKRIVTFLLRERLKRYDFKLYNKKDQETIYSPYSILGIGMKELELK
SGFPEHYLWVGPFGSSIERAENYPFDLSPYEGYKKVLVSCGTQLAWAKDNLLYQTQQLAE
AHPDCHFFVTLGFGGQDFRCEELMDNVSVVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIY
DKPALILPHDYDQYDYAVRGLETGIALTTKREDTEAIGRAFDELLARDDWPDLNKLSRAA
QIYQPTEILKSEIHRLLGNKEK
>A0A0F0LAE8|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Microbacterium oxydans|TrEMBL
MTEKSVLITSSPLLGHLTPGVLIGAELARRGHRVRVLTGARHRERVERAGLEFVPLDVAA
DFDDRDMRSAFPQVADLTGIRGLSAGVLEVFSKPVDAQFASVERALGDVPTDVVLSEMLF
AGVYPLALLPKSERPRIGILGISPMTLGAPGLPPYGMGLLPATGPIGSLRNWILYQAANR
VVLRPAQKYLAQAMRRLTDTTLSVPFFEMPGLGDALIHLGTQGFEYPRPRPRTRLIFAGP
LSSRNVGGEVPDWAEDIEGRKVVHVTQGTVANADLRELVVPTVESLRGTETLVVITGGGR
PADEVLTELRQHLGELPDNIRVSTFLDYEWLFPRIQLFITNGGYGGVNEALRHAVPVVVV
GNTEDKPEVAARVEWSRVGVRVRSTLPSAGEMRKAIDLVLGDPSFRDRAATMSEEIASSP
GLDVIEEFVTQPSGAASADNSPST
>A0A3N6FRV7|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces sp. ADI91-18|TrEMBL
MRVLFTVPPLAGHVNPTVAVGAELASRGHEVAWCGPAGALARLLPAHARILPAGEEAGGA
YEALHARWRDLRGVGALRFLWEEALVPLARAMTPGVTDAVRAFAPDLVVADQQALAGPLV
ARRLGIPWATSATTSAELTRPFADFPKVGEWVEGQIAGLLAAYGEDASGWDPRFSERLVL
VFSTPELVGAADRFPAHYAFVGPAFGARPAAPVFPWHRLDPDRRRVLVSLGTLNQEAGER
FYGAVLEAAGQLGRDVQLVLVAPAALIGAVPANVLVRDGVPQLELLPHLDAVVCHGGHNT
VCEALAHGLPLVVAPIRDDQPIVARQVVEAGAGVRVRFGRPRAEELRDALTAVLDDPGPR
RAARRIQASFAAAGGTAAAADRLEKLL
>A0A517WVW7|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Gimesia aquarii|TrEMBL
MNILIITVGTQGDVQPYVALGKGLKAAGHSVTVCTCAYFESFVTAHGLDYAFMNDDLIKF
MHSDDGKIAMENTGNLWEAIRTAIKIIPTVGPMQRRQIDDSWQATQAVQPDLILYHPKAL
CAPDFAERLGVLSIIGFYLPLFAVTGDFPAMGLPQWKLGRWYNRLTHGLINKATWWGMRK
HISAWRKENDLPRKQGIDFLNQSDGQPAPALYAFSESVIPRPTDWPENARVSGYWFLDQI
DDWKPPAELQEFLSNGEPPIYFGFGSIFGQDPLRLTKIIVEAVKATGVRAILARGWGGLD
LDQIELPETIFKLDFAPHDWLFPQVAAVVHHGGCGTTAAGLRAGRPSILCPFFGDQPFWG
SIIENLGVGPTPLPQKKLTVEKLSAAIRQVTTDTAMIEKADQIGQRIRSEDGVANAVKFI
DQWLARDSELSLVDRKSDGLQ
>A0A8B3IXT7|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptococcus oralis|TrEMBL
MRKIKIDVVVVPLSGHLFPTLNLLAPLLKDPLYEIRLFTGPQRKTVAEEMGFRVIPILEN
CVDEFERVANNEGQLNLFSAYRQLSASLDLINVVSDQLVQEWQENRPDIVIADFITLSGG
LVAEQLNIPWITTMATQFAIETTDGPPCFFGGMGSPKTSFQSGLQWLGRKGTRLGKRIVS
FLLRERLKRYDFRLYNQKGQETIYSPYSILGIGMKELELKSGFPEHYLWVGPFGSSIERA
ENYPLDLSPYAGYKKVLVSCGTQLAWAKDNLLYQTQQLAEAHPDCHFFVTLGFGGQDFQC
EELMDNVSVVSYLPYKEYIPQMDYVIHHGGAGIFYQCIIYGKPALILPHDYDQYDYAVRG
LEAGIALTAKREDTEAIGRAFDELLARDDWPDLNRLSRAAQIYQPTEILKSEIHRLLGDK
EK
>A0A385XYI1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Dickeya dianthicola|TrEMBL
MSHILMAAVATPGHVYPMLTIARHLLTKGHRVTLFSGALFREQAQAAGVGFIAFDEQIDF
DYRHLERHFPKRATLPPGNAQMALALREFFSAPIPLIDRQLRAVLAQTGADVVMAENCFY
GILPLLASEDRPPVIGIGVTPLSFSSRDSIFYGPRIPPALLPPDLTREQLIDEETRELIA
GVKEAFDTVMVQSGQQPLTAPFADALISGCDRFLQLSTTELEYHRDDLPSCVRFVGPLPL
KVTEEETDQALWPSQDTRPLVIVSQGTLANVDLQQLIGPTLRALAGLPVRVLATTGGRPV
EELAASAPANARVCRFISLEHWLPRAALLITNGGYGSLNAALSHGVPLIVAGTGEDKLET
AARVVFAGCGLNLGTSTPGERQIADAVTRILEQPGYTQRARWVQSDCARHHALEAIAEEV
GAIG
>A0A143QPX2|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Rhodococcus fascians|TrEMBL
MWHAERVRVAVVAGPDPGHAFPAIALSLLFERAGDDPVLFTGSRWVGDARAAGLRTLPLG
GLLPRPEDDDLDAGQRIHSRAAFVATELLPDLERENVDLVVSDILTAGGGMAAERLGIPW
VELSPHPLYSPSKGLPPIGSGLAPGRGVRGRLRDTVMRALTARSIARGQQQRADARVSIG
LPARDPGPAARLIATIPALEVPRPDWPRDAHVVGPLLWEPTDELLDVPAGDTPLVMVAPS
TAFTGAEGMLEMALNGLDGTGVRVVASVLDGGPDDVPEWANAGLGRQDELLRRADVVVCG
GGHGMLAKALIHGVPVVTVPGGGDQWELANRAARQGSAVLVRPATAGAIADAVSAVLSDP
RHAAAATSAAAGAHHVEDPVSVCREVLAGSDAEGGR
>A0A2P4UCN0|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Actinomadura rubteroloni|TrEMBL
MRARRVQVPSLDTLLGTAPVPPEDDGPERRRFLFAVPAVAGAVAPARAVAEELAARGHRV
AWAGHRERLEPLLRGGSRVFHAEDPAWTAALDTARREGRDLRGPAALRFRWERLLIPLGH
AMLPGVENAVDRFRPDVVVADQDVLAAPVVARRRGLPWATSASTSAEFTRPLAALPLVEE
WIRDLIGGFQLDNGIEDLVDLRFSDHLALVYSTAALFGDVSYFPDHVAFVGPALGAPPRG
DFPLDRLDGRPAVLVTLGGADGPGAARFLRAAADALAGMDVQAVVVATDALLPDPPPNAL
VFPHVPQRALLEHMAAVVSHGGHTTVTEALAQGLPQVVAPIRDDQPVVARQVEACGAGRS
VRFGRCTAADLRAALADVLTDASYRTAAGRVRASFHGAGGAAAAADRLEKLT
>A0A1S8S2B2|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Clostridium beijerinckii|TrEMBL
MKVVFLTLGSRGDVQPYVALAKELIKSRHEALVCTGASFKSFVKENGVTFCEASADLMAV
LESEEGKKIFNGGHYNVFRMLKYAKEVITPAYRKSMDDFLEASKGADIIVYHPKALGAVD
ISEYLNIPCISMPPIPIVYPITEFPNLAISANKNFGPFLNKLSYKASSLGELSYMKHIND
FRKKSLHLPKRKAGELAFKVNGKNIPIVYPISPFLFKEVDTWSESVFLSGFFFLDIVETE
LDDEMEEFLKSGVRPIVVSFSSMPLKDPKIFKDKLIKALKETGDRAIVLTGTSGMTFEND
DNIMAVKKASHRLLFRRAKCIIHHGGVGTMSEALLSGVPQLIMPFTVDQPFWANRLYLKG
LTTHPLKEKNLKVYDLVKAFKEMENDKYIRNAEEIKNIIESEKGLENAVKYIERVYKTF
>A0A5P9PXP8|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Amycolatopsis sp. YIM 10|TrEMBL
MAPESPSRPILFVSYSESGLLNPMLVLAEELSRRGVAGLWFATDENRRAAVEKLNAGSPV
EFFSLGDPVPELSSTTWDDETYRLVTQKSKFKARRAVIEQTDKPRLRMAKYRKLEEAVEK
IGPALLVIESMCRFGIELAITKKIPYVLSVPFVPSNLLTSYVPIGKSYTPKGFPIPHSGL
PFRGTLAQRLSNRLFGWRTLTMAMSKEMRARQAEDAHVREELGVAPEAFGQFVRVEKAEL
VLCNTIPELDYPFELPEKVRTVGALVPPLPESDDTELADWLSARDSVIYMGFGTITRLTA
EQVGALVEVARRLDGEHDVLWKLPAEQQKWLPPADQLPGNLRIESWVPSQLDVLAHPSVK
LFFSHGGGNAYNESVYFGKPQVMRPLWVDCFDQAVRGESFGISLTLDRPHDMDVDDVLDK
VTRVLGNSAFRTRAERLSRLQHQAGGREKAAELILGLPAMAKD
>A0A3G4VUK1|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Streptomyces sp. ADI95-16|TrEMBL
MRVLFTVPPLAGHVNPTVAVGAELASRGHEVAWCGPAGALARLLPAPARILPAGEEAGGA
YEALHARWRDLRGVGALRFLWEEALVPLARAMTPGVTDAVRAFAPDLVVADQQALAGPLV
ARRLGIPWATSATTSAELTRPFADFPKVGEWVEGQIAGLLAACGEDASGWDPRFSERLVL
VFSTPELVGAADRFPAHYAFVGPAFGARPAAPVFPWHRLDPDRRRVLVSLGTLNQEAGDR
FYGAVLEAAGHLGRDVQLVLVAPAALIGAVPANVLVQDGVPQLELLPHLDAVVCHGGHNT
VCEALAHGLPLVVAPIRDDQPIVARQVVEAGAGVRVRFGRPRAEELRDALTAVLDDPGPR
RAARRIQASFAAAGGTAAAADRLEKLL
>A0A517N277|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Adhaeretor mobilis|TrEMBL
MHLLLTALGSYGDVLPMVGLGAAMRERGHEVSVITNPHFREETESAGLDLVPLGTIEEYE
ELTSHPDLWRPIRGPKIMMELVATFARELYDTISDHYRVGETVLGSHGLDLAGRTFSEKQ
IQQGNRAPQATIHYAPLALRTMHDTPNFIGAFTQPPTPRWLKRLQFWLGDKLVIDRILGK
EVNGLRAELGLPPVSRIYRQWHNSPELTLCFWPEWFGPKQPDWPHSAELVGFPLYDSDPA
AELSEDVETFLNAGEPPIAFAPGSANTQAAKFFQTAVGVCEKLDRRGVLLTKYPQQIPDD
LPPSVQHFAFVPFSKLLPRVAALVHHGGIGSCAQALSAGVPQLVMPMSYDQLDNATRLKR
LGTGDLVMPKQFKTHKVAQRLAELFQQPSIHESCQQLAKRCDGAVAIRGACENFERLFND
TEKGKR
>A0A4R8SW90|4'-demethylrebeccamycin synthase|EC 4.3.3.5|Mycobacteroides salmoniphilum|TrEMBL
MKGSAMKFVLSFYGTRGDVEPGIAVGRELLRRGHDVRMVVPPDLVDFTEAAGLSAVACGP
DVRVWQDVNRDFWARFLRNFWKNFWRIRDLRELLREDWRFLVQCWEDVSTTLRSQAADAD
LLFTGVLGEESAGNVAEFYSLPFATLHVFPIRANGQLVPGMPARLGRSIMRLSEWLGWPM
FKRLEDPQRRELGLPKATGPSPWRIAERGSLEIQAYDEACMPGLAEEWAEYDGLRPFVGA
LTLDLPTDSDDEVASWIGGGQPPICFGFGSMPVESAAETLAMISAACDQLGERALVCAGG
SDFSHVPLFENVKVVGVMNYSAAFPACRAVVHHGGAGTTAASLRAGVPTLVLSTDLDQTL
WGARVKRLKVGTARRFSATTEKTLVADLRTILDAAYVTRAREVAARMTKAADSPVTAADL
LEDFVRLKRAG