>Q03131|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Saccharopolyspora erythraea|Swiss-Prot
MSGPRSRTTSRRTPVRIGAVVVASSTSELLDGLAAVADGRPHASVVRGVARPSAPVVFVF
PGQGAQWAGMAGELLGESRVFAAAMDACARAFEPVTDWTLAQVLDSPEQSRRVEVVQPAL
FAVQTSLAALWRSFGVTPDAVVGHSIGELAAAHVCGAAGAADAARAAALWSREMIPLVGN
GDMAAVALSADEIEPRIARWDDDVVLAGVNGPRSVLLTGSPEPVARRVQELSAEGVRAQV
INVSMAAHSAQVDDIAEGMRSALAWFAPGGSEVPFYASLTGGAVDTRELVADYWRRSFRL
PVRFDEAIRSALEVGPGTFVEASPHPVLAAALQQTLDAEGSSAAVVPTLQRGQGGMRRFL
LAAAQAFTGGVAVDWTAAYDDVGPNPALCRSSRRPRRKTSRPSPASTGTRHRTCCERLLA
VVNGETAALAGREADAEATFRELGLDSVLAAQLRAKVSAAIGREVNIALLYDHPTPRALA
EALAAGTEVAQRETRARTNEAAPGEPVAVVAMACRLPGGVSTPEEFWELLSEGRDAVAGL
PTDRGWDLDSLFHPDPTRSGTAHQRGGGFLTEATAFDPAFFGMSPREALAVDPQQRLMLE
LSWEVLERAGIPPTSLQASPTGVFVGLIPQEYGPRLAEGGEGVEGYLMTGTTTSVASGRI
AYTLGLEGPAISVDTACSSSLVAVHLACQSLRRGESSLAMAGGVTVMPTPGMLVDFSRMN
SLAPDGRCKAFSAGANGFGMAEGAGMLLLERLSDARRNGHPVLAVLRGTAVNSDGASNGL
SAPNGRAQVRVIQQALAESGLGPADIDAVEAHGTGTRLGDPIEARALFEAYGRDREQPLH
LGSVKSNLGHTQAAAGVAGVIKMVLAMRAGTLPRTLHASERSKEIDWSSGAISLLDEPEP
WPAGARPRRAGVSSFGISGTNAHAIIEEAPQVVEGERVEAGDVVAPWVLSASSAEGLRAQ
AARLAAHLREHPGQDPRDIAYSLATGRAALPHRAAFAPVDESAALRVLDGLATGNADGAA
VGTSRAQQRAVFVFPGQGWQWAGMAVDLLDTSPVFAAALRECADALEPHLDFEVIPFLRA
EAARREQDAALSTERVDVVQPVMFAVMVSLASMWRAHGVEPAAVIGHSQGEIAAACVAGA
LSLDDAARVVALRSRVIATMPGNKGMASIAAPAGEVRARIGDRVEIAAVNGPRSVVVAGD
SDELDRLVASCTTECIRAKRLAVDYASHSSHVETIRDALHAELGEDFHPLPGFVPFFSTV
TGRWTQPDELDAGYWYRNLRRTVRFADAVRALAEQGYRTFLEVSAHPILTAAIEEIGDGS
GADLSAIHSLRRGDGSLADFGEALSRAFAAGVAVDWESVHLGTGARRVPLPTYPFQRERV
WLEPKPVARRSTEVDEVSALRYRIEWRPTGAGEPARLDGTWLVAKYAGTADETSTAAREA
LESAGARVRELVVDARCGRDELAERLRSVGEVAGVLSLLAVDEAEPEEAPLALASLADTL
SLVQAMVSAELGCPLWTVTESAVATGPFERVRNAAHGALWGVGRVIALENPAVWGGLVDV
PAGSVAELARHLAAVVSGGAGEDQLALRADGVYGRRWVRAAAPATDDEWKPTGTVLVTGG
TGGVGGQIARWLARRGAPHLLLVSRSGPDADGAGELVAELEALGARTTVAACDVTDRESV
RELLGGIGDDVPLSAVFHAAATLDDGTVDTLTGERIERASRAKVLGARNLHELTRELDLT
AFVLFSSFASAFGAPGLGGYAPGNAYLDGLAQQRRSDGLPATAVAWGTWAGSGMAEGAVA
DRFRRHGVIEMPPETACRALQNALDRAEVCPIVIDVRWDRFLLAYTAQRPTRLFDEIDDA
RRAAPQAPAEPRVGALASLPAPEREEALFELVRSHAAAVLGHASAERVPADQAFAELGVD
SLSALELRNRLGAATGVRLPTTTVFDHPDVRTLAAHLAAELGGATGAEQAAPATTAPVDE
PIAIVGMACRLPGEVDSPERLWELITSGRDSAAEVPDDRGWVPDELMASDAAGTRAHGNF
MAGAGDFDAAFFGISPREALAMDPQQRQALETTWEALESAGIPPETLRGSDTGVFVGMSH
QGYATGRPRPEDGVDGYLLTGNTASVASGRIAYVLGLEGPALTVDTACSSSLVALHTACG
SLRDGDCGLAVAGGVSVMAGPEVFTEFSRQGALSPDGRCKPFSDEADGFGLGEGSAFVVL
QRLSDARREGRRVLGVVAGSAVNQDGASNGLSAPSGVAQQRVIRRAWARAGITGADVAVV
EAHGTGTRLGDPVEASALLATYGKSRGSSGPVLLGSVKSNIGHAQAAAGVAGVIKVLLGL
ERGVVPPMLCRGERSGLIDWSSGEIELADGVREWSPAADGVRRAGVSAFGVSGTNAHVII
AEPPEPEPVPQPRRMLPATGVVPVVLSARTGAALRAQAGRLADHLAAHPGIAPADVSWTM
ARARQHFEERAAVLAADTAEAVHRLRAVADGAVVPGVVTGSASDGGSVFVFPGQGAQWEG
MARELLPVPVFAESIAECDAVLSEVAGFSVSEVLEPRPDAPSLERVDVVQPVLFAVMVSL
ARLWRACGAVPSAVIGHSQGEIAAAVVAGALSLEDGMRVVARRSRAVRAVAGRGSMLSVR
GGRSDVEKLLADDSWTGRLEVAAVNGPDAVVVAGDAQAAREFLEYCEGVGIRARAIPVDY
ASHTAHVEPVRDELVQALAGITPRRAEVPFFSTLTGDFLDGTELDAGYWYRNLRHPVEFH
SAVQALTDQGYATFIEVSPHPVLASSVQETLDDAESDAAVLGTLERDAGDADRFLTALAD
AHTRGVAVDWEAVLGRAGLVDLPGYPFQGKRFWLLPDRTTPRDELDGWFYRVDWTEVPRS
EPAALRGRWLVVVPEGHEEDGWTVEVRSALAEAGAEPEVTRGVGGLVGDCAGVVSLLALE
GDGAVQTLVLVRELDAEGIDAPLWTVTFGAVDAGSPVARPDQAKLWGLGQVASLERGPRW
TGLVDLPHMPDPELRGRLTAVLAGSEDQVAVRADAVRARRLSPAHVTATSEYAVPGGTIL
VTGGTAGLGAEVARWLAGRGAEHLALVSRRGPDTEGVGDLTAELTRLGARVSVHACDVSS
REPVRELVHGLIEQGDVVRGVVHAAGLPQQVAINDMDEAAFDEVVAAKAGGAVHLDELCS
DAELFLLFSSGAGVWGSARQGAYAAGNAFLDAFARHRRGRGLPATSVAWGLWAAGGMTGD
EEAVSFLRERGVRAMPVPRALAALDRVLASGETAVVVTDVDWPAFAESYTAARPRPLLDR
IVTTAPSERAGEPETESLRDRLAGLPRAERTAELVRLVRTSTATVLGHDDPKAVRATTPF
KELGFDSLAAVRLRNLLNAATGLRLPSTLVFDHPNASAVAGFLDAELGTEVRGEAPSALA
GLDALEGALPEVPATEREELVQRLERMLAALRPVAQAADASGTGANPSGDDLGEAGVDEL
LEALGRELDGD
>Q03132|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Saccharopolyspora erythraea|Swiss-Prot
MTDSEKVAEYLRRATLDLRAARQRIRELESDPIAIVSMACRLPGGVNTPQRLWELLREGG
ETLSGFPTDRGWDLARLHHPDPDNPGTSYVDKGGFLDDAAGFDAEFFGVSPREAAAMDPQ
QRLLLETSWELVENAGIDPHSLRGTATGVFLGVAKFGYGEDTAAAEDVEGYSVTGVAPAV
ASGRISYTMGLEGPSISVDTACSSSLVALHLAVESLRKGESSMAVVGGAAVMATPGVFVD
FSRQRALAADGRSKAFGAGADGFGFSEGVTLVLLERLSEARRNGHEVLAVVRGSALNQDG
ASNGLSAPSGPAQRRVIRQALESCGLEPGDVDAVEAHGTGTALGDPIEANALLDTYGRDR
DADRPLWLGSVKSNIGHTQAAAGVTGLLKVVLALRNGELPATLHVEEPTPHVDWSSGGVA
LLAGNQPWRRGERTRRARVSAFGISGTNAHVIVEEAPEREHRETTAHDGRPVPLVVSART
TAALRAQAAQIAELLERPDADLAGVGLGLATTRARHEHRAAVVASTREEAVRGLREIAAG
AATADAVVEGVTEVDGRNVVFLFPGQGSQWAGMGAELLSSSPVFAGKIRACDESMAPMQD
WKVSDVLRQAPGAPGLDRVDVVQPVLFAVMVSLAELWRSYGVEPAAVVGHSQGEIAAAHV
AGALTLEDAAKLVVGRSRLMRSLSGEGGMAAVALGEAAVRERLRPWQDRLSVAAVNGPRS
VVVSGEPGALRAFSEDCAAEGIRVRDIDVDYASHSPQIERVREELLETTGDIAPRPARVT
FHSTVESRSMDGTELDARYWYRNLRETVRFADAVTRLAESGYDAFIEVSPHPVVVQAVEE
AVEEADGAEDAVVVGSLHRDGGDLSAFLRSMATAHVSGVDIRWDVALPGAAPFALPTYPF
QRKRYWLQPAAPAAASDELAYRVSWTPIEKPESGNLDGDWLVVTPLISPEWTEMLCEAIN
ANGGRALRCEVDTSASRTEMAQAVAQAGTGFRGVLSLLSSDESACRPGVPAGAVGLLTLV
QALGDAGVDAPVWCLTQGAVRTPADDDLARPAQTTAHGFAQVAGLELPGRWGGVVDLPES
VDDAALRLLVAVLRGGGRAEDHLAVRDGRLHGRRVVRASLPQSGSRSWTPHGTVLVTGAA
SPVGDQLVRWLADRGAERLVLAGACPGDDLLAAVEEAGASAVVCAQDAAALREALGDEPV
TALVHAGTLTNFGSISEVAPEEFAETIAAKTALLAVLDEVLGDRAVEREVYCSSVAGIWG
GAGMAAYAAGSAYLDALAEHHRARGRSCTSVAWTPWALPGGAVDDGYLRERGLRSLSADR
AMRTWERVLAAGPVSVAVADVDWPVLSEGFAATRPTALFAELAGRGGQAEAEPDSGPTGE
PAQRLAGLSPDEQQENLLELVANAVAEVLGHESAAEINVRRAFSELGLDSLNAMALRKRL
SASTGLRLPASLVFDHPTVTALAQHLRARLVGDADQAAVRVVGAADESEPIAIVGIGCRF
PGGIGSPEQLWRVLAEGANLTTGFPADRGWDIGRLYHPDPDNPGTSYVDKGGFLTDAADF
DPGFFGITPREALAMDPQQRLMLETAWEAVERAGIDPDALRGTDTGVFVGMNGQSYMQLL
AGEAERVDGYQGLGNSASVLSGRIAYTFGWEGPALTVDTACSSSLVGIHLAMQALRRGEC
SLALAGGVTVMSDPYTFVDFSTQRGLASDGRCKAFSARADGFALSEGVAALVLEPLSRAR
ANGHQVLAVLRGSAVNQDGASNGLAAPNGPSQERVIRQALAASGVPAADVDVVEAHGTGT
ELGDPIEAGALIATYGQDRDRPLRLGSVKTNIGHTQAAAGAAGVIKVVLAMRHGMLPRSL
HADELSPHIDWESGAVEVLREEVPWPAGERPRRAGVSSFGVSGTNAHVIVEEAPAEQEAA
RTERGPLPFVLSGRSEAVVAAQARALAEHLRDTPELGLTDAAWTLATGRARFDVRAAVLG
DDRAGVCAELDALAEGRPSADAVAPVTSAPRKPVLVFPGQGAQWVGMARDLLESSEVFAE
SMSRCAEALSPHTDWKLLDVVRGDGGPDPHERVDVLQPVLFSIMVSLAELWRAHGVTPAA
VVGHSQGEIAAAHVAGALSLEAAAKVVALRSQVLRELDDQGGMVSVGASRDELETVLARW
DGRVAVAAVNGPGTSVVAGPTAELDEFFAEAEAREMKPRRIAVRYASHSPEVARIEDRLA
AELGTITAVRGSVPLHSTVTGEVIDTSAMDASYWYRNLRRPVLFEQAVRGLVEQGFDTFV
EVSPHPVLLMAVEETAEHAGAEVTCVPTLRREQSGPHEFLRNLLRAHVHGVGADLRPAVA
GGRPAELPTYPFEHQRFWPRPHRPADVSALGVRGAEHPLLLAAVDVPGHGGAVFTGRLST
DEQPWLAEHVVGGRTLVPGSVLVDLALAAGEDVGLPVLEELVLQRPLVLAGAGALLRMSV
GAPDESGRRTIDVHAAEDVADLADAQWSQHATGTLAQGVAAGPRDTEQWPPEDAVRIPLD
DHYDGLAEQGYEYGPSFQALRAAWRKDDSVYAEVSIAADEEGYAFHPVLLDAVAQTLSLG
ALGEPGGGKLPFAWNTVTLHASGATSVRVVATPAGADAMALRVTDPAGHLVATVDSLVVR
STGEKWEQPEPRGGEGELHALDWGRLAEPGSTGRVVAADASDLDAVLRSGEPEPDAVLVR
YEPEGDDPRAAARHGVLWAAALVRRWLEQEELPGATLVIATSGAVTVSDDDSVPEPGAAA
MWGVIRCAQAESPDRFVLLDTDAEPGMLPAVPDNPQLALRGDDVFVPRLSPLAPSALTLP
AGTQRLVPGDGAIDSVAFEPAPDVEQPLRAGEVRVDVRATGVNFRDVLLALGMYPQKADM
GTEAAGVVTAVGPDVDAFAPGDRVLGLFQGAFAPIAVTDHRLLARVPDGWSDADAAAVPI
AYTTAHYALHDLAGLRAGQSVLIHAAAGGVGMAAVALARRAGAEVLATAGPAKHGTLRAL
GLDDEHIASSRETGFARKFRERTGGRGVDVVLNSLTGELLDESADLLAEDGVFVEMGKTD
LRDAGDFRGRYAPFDLGEAGDDRLGEILREVVGLLGAGELDRLPVSAWELGSAPAALQHM
SRGRHVGKLVLTQPAPVDPDGTVLITGGTGTLGRLLARHLVTEHGVRHLLLVSRRGADAP
GSDELRAEIEDLGASAEIAACDTADRDALSALLDGLPRPLTGVVHAAGVLADGLVTSIDE
PAVEQVLRAKVDAAWNLHELTANTGLSFFVLFSSAASVLAGPGQGVYAAANESLNALAAL
RRTRGLPAKALGWGLWAQASEMTSGLGDRIARTGVAALPTERALALFDSALRRGGEVVFP
LSINRSALRRAEFVPEVLRGMVRAKLRAAGQAEAAGPNVVDRLAGRSESDQVAGLAELVR
SHAAAVSGYGSADQLPERKAFKDLGFDSLAAVELRNRLGTATGVRLPSTLVFDHPTPLAV
AEHLRDRLFAASPAVDIGDRLDELEKALEALSAEDGHDDVGQRLESLLRRWNSRRADAPS
TSAISEDASDDELFSMLDQRFGGGEDL
>Q03133|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Saccharopolyspora erythraea|Swiss-Prot
MSGDNGMTEEKLRRYLKRTVTELDSVTARLREVEHRAGEPIAIVGMACRFPGDVDSPESF
WEFVSGGGDAIAEAPADRGWEPDPDARLGGMLAAAGDFDAGFFGISPREALAMDPQQRIM
LEISWEALERAGHDPVSLRGSATGVFTGVGTVDYGPRPDEAPDEVLGYVGTGTASSVASG
RVAYCLGLEGPAMTVDTACSSGLTALHLAMESLRRDECGLALAGGVTVMSSPGAFTEFRS
QGGLAADGRCKPFSKAADGFGLAEGAGVLVLQRLSAARREGRPVLAVLAGSAVNQDGASN
GLTAPSGPAQQRVIRRALENAGVRAGDVDYVEAHGTGTRLGDPIEVHALLSTYGAERDPD
DPLWIGSVKSNIGHTQAAAGVAGVMKAVLALRHGEMPRTLHFDEPSPQIEWDLGAVSVVS
QARSWPAGERPRRAGVSSFGISGTNAHVIVEEAPEADEPEPAPDSGPVPLVLSGRDEQAM
RAQAGRLADHLAPEPRNSLRDTGFTLATRASAMEHRAVVVGDRDEALAGLRAVADRRIAD
RTATGQGPNSPRRVAMVFPGQGAQWQGMARDLLRESQVFADSIRDCERALAPHVDWSLTD
LLSGARPLDRVDVVQPALFAVMVSLAALWRSHGVEPAAVVGHSQGEIAAAHVAGALTLED
AAKLVAVRSRVLRRLGGQGGMASFGLGTEQAAERIGRFAGALSIASVNGPRSVVVVAGES
GPLDELIAECEAEAHKARRIPVDYASHSPQVESLREELLTELAGISPVSADVALYSTTTG
QPIDTATMDTAYWYANLREQVRFQDATRQLAEAGFDAFVEVSPHPVLTVGIEATLDSALP
ADAGACVVGTLRRDRGGLADFHTALGEAYAQGVEVDWSPAFADARPVELPVYPFQRYWLP
IPTGGRARDEDDDWRYQVVWREAEWESASLAGRVLLVTGPGVPSELSDAIRSGLEQSGAT
VLTCDVESRSTIGTALEAADTDALSTVGVAAVPHGEAVDPSLDALALVQALGAAGVEAPL
WVLTRNAVQVADGELVDPAQAMVGGLGRVVGIEQPGRWGGLVDLVDADAASIRSLAAVLA
DPRGEEQVAIRADGIKVARLVPAPARARTHPLEPLAGTVLVTGGTGGIGAHLARWLARSG
AEHLVLLGRRGADAPGASELREELTALGTGVTIAACDVADRARLEAVLAAEAAAEGRTVS
AVMHAAGVSTSTPLDDLTEAEFTEIADVKVRGTVNLDELCPDLDAFVLFSSNAGVWGSPG
LASYAAANAFLDGFARAARSEGAPVTSIAWGLWAGQNMAGDEGGEYLRSQGLRAMDPDRA
VEELHITLDHGQTSVSVVDMDRRRFVELFTAARHRPLFDEIAGARAEARQSEEGPALAQR
LAALLCDGREREHLAHLIRAEVAAVLGHGDDAAIDRDRAFRDLGFDSMTAVDLRNRLAAV
TGVREAATVVFDHPTITRLADHYLERLVGAAEAEQAPALVREVPPKDADDPIAIVGMACR
FPGGVHNPGELWEFIVGGGDAVTEMPTDRGWDLDALFDPDPQRHGTSYSRHGAFLDGAAD
FDAAFFGISPREALAMDPQQRQVLETTWELFENAGIDPHSVRGSDTGVFLGAAYQGYGQD
AVVPEDSEGYLLTGNSSAVVSGRVAYVLGLEGPAVTVDTACSSSLVALHSACGSLRDGDC
GLAVAGGVSVMAGPEVFTEFSRQGGLAVDGRCKAFSAEADGFGLPEGVAVVQLQRLSDGP
AEGGRQVLGVVAGSAINQDGATNGLAAPSGVAQQRVIRKAWARAGITGADVAVVEAHGTG
TRLGDPVEASALLATYGKSRGSSGPVLLGSVKSNIGHAQAAAGVAGVIKVVLGLNRGLVP
PMLCRGERSPLIEWSSGGVELAEAVSPWPPAADGVRRAGVSAFGVSGTNAHVIIAEPPEP
EPLPEPGPVGVLAAANSVPVLLSARTETALAAQARLLESAVDDSVPLTALASALATGRAH
LPRRAALLAGDHEQLRGQLRAVAEGVAAPGATTGTASAGGVVFVFPGQGAQWEGMARGLL
SVPVFAESIAECDAVLSEVAGFSASEVLEQRPDAPSLERVDVVQPVLFSVMVSLARLWGA
CGVSPSAVIGHSQGEIAAAVVAGVLSLEDGVRVVALRAKALRALAGKGGMVSLAAPGERA
RALIAPWEDRISVAAVNSPSSVVVSGDPEALAELVARCEDEGVRAKTLPVDYASHSRHVE
EIRETILADLDGISARRAAIPLYSTLHGERRDMGPRYWYDNLRSQVRFDEAVSAQSPDGH
ATFVEMSPHPVLTAAVQEIAADAVAIGSLHRDTAEEHLIAELARAHVHGVAVDWRNVFPA
APPVALPNYPFEPQRYWLAPEVSDQLADSRYRVDWRPLATTPVDLEGGFLVHGSAPESLT
SAVEKAGGVVPVASADREALAAALREVPGEVAGVLSVHTGAANALALHQSLGEAGVRAPL
WLVTSRAVALGESEPVDPEQAMVWGLGRVMGLETPERWGGLVDLPAEPAPGDGEAFVACL
GADGHEDQVAIRDHARYGRRLVRAPLGTRESSWEPAGTALVTGGTGALGGHVARHLARCG
VEDLVLVSRRGVDAPAAAELEAELVALGPKTTITACDVADREQLSKLLEELRGQGRPVRT
VVHTAGVPESRPLHEIGELESVCAAKVTGARLLDELCPDAETFVLFSSGAGVWGSANLGA
YSAANAYLDALAHRRRAEGRAATSVAWGAWAGEGMATGDLEGLTRRGLRPMAPDRAIRAL
HQALDNGDTCVSIADVDWEAFAVGFTAARPRPLLDELVTPAVGAVPAVQAAPAREMTSQE
LLEFTHSHVAAILGHSSPDAVGQDQPFTELGFDSLTAVGLRNQLQQATGLALPATLVFEH
PTVRRLADHIGQQLDSGTPAREASSALRDGYRQAGVSGRVRSYLDLLAGLSDFREHFDGS
DGFSLDLVDMADGPGEVTVICCAGTAAISGPHEFTRLAGALRGIAPVRAVPQPGYEEGEP
LPSSMAAVAAVQADAVIRTQGDKPFVVAGHSAGALMAYALATELLDRGHPPRGVVLIDVY
PPGHQDAMNAWLEELTATLFDRETVRMDDTRLTALGAYDRLTGQWRPRETGLPTLLVSAG
EPMGPWPDDSWKPTWPFEHDTVAVPGDHFTMVQEHADAIARHIDAWLGGGNS
>A0A291T2Z0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces malaysiensis|TrEMBL
MSNEEKLLDHLKWVTAELRQTRQRLREAESAEPEPIAIVGMACRYPGGVRSPEELWRLVR
DGEDAVSGFPTDRGWGTEELFDPDPESYGKSYVDQGGFCYDATEFDASFFDISPREAQTM
DPQQRLLLETAWEAFERAGLTQESLSGSNTGVFAGVGSHDYLSVIGNITSEVEGYVGAGN
LGSVVSGRVAYSLGLEGPAVTVDTACSSSLVAIHLACQALRNGECDLALAGGVAVMATPG
GFIEFSRQRGMAPDGRCKPFAAAADGTGWGEGSGLIVLERLCEAQRRDRRVLGVIRGSAV
NQDGASNGLTAPNGPSQQRVIRQALANAQLSTAEVDAVDGHGTGTTLGDPIEAQALLATY
GQGRPEDRPLWLGSIKSNLGHTQAAAGAAGVIKMVMAMRHELLPASLHIDEPTPHADWAS
GAVRLLTEPVPWPRGERARRAGVSAFGISGTNAHLILEQAPAPAGTPSVTTVPTDGDGVP
AGGVVPWVVSGRGAEALRGQARALAERVATDPDASPAEVGWSLISTRSVFDHRAVIVGEH
RDELLAGLNALATGDTHPTLTEPTTTTGPGAGGMGPVLVFPGQGSQWPGMGAGLLDTSPV
FATRIAECEHALTPHVDWSLTEVLRGGVNAADLARVDVVQPVLWAVMISLAAVWDHHGLT
PTAVIGHSQGEIAAACVAGALSLDEGARIVALRAHALRRLAGHGAMASLTTSQTHTEELL
TNLGEPAREVGIAAVNGPGSVVVSGPPEQVTHAITACEQAGHRARLIDVDYASHSAQVDE
IAEELREVLSGIEPVQAEVAFYSTVTGARMDTSGLDTAYWVKNLRERVRFADAVRALLHD
GHRVFIEASTHPVLTIGMQETFEEAGVPAAAVPTLRRDHGDQAQLLRSVAQAFTAGVAVD
WTRWFRTDPAPRTIDLPTYAFQRRRYWLDGRGGHSGDPGDLGLGSAGHPLLGAAVELAEG
GAHLLTGRLSPRTHPWLNDHRVLDTVLLPGTAFAELALHAAARTGCDHVSELTLHAPLVI
PQGEAVDVQIAVAAPDHTGERPITVHSRPAAEGDDGAWTRHATGALATSPPANPVSLSGT
WPPPGATPLPVEDFYRQLADHGYHYGPSFQGLTAAWRLDGDVYAEVSLPEGEREGAAAYG
IHPALFDAALHARALDVAPGSEDARRILLPFTWSGLRLCATGADTLRIRITPTAPDRLAL
LAADPTGAAVAVVDDLILRPVPDGQLGRARAAGRNSLFQLVWTRMTPTAPAPTCRSAVIG
PDGGPPADALRDAARLPDLAAVRATVTDGAPPPDVVFASFGSSADGRGDPGDPGDPVART
HDLGKEALGVLREFLATPEFADARLAVVTRGAVATQSHDDVHDLPASAVWGLVRSAQSEN
PGRVLLLDLDERDTSLRSLPDAVASGEPQLALRDGVAYVPRLVHDDAAKRLTPPEGAATW
RLGLTGHGSLDQLALVDCPDNTRPLDRGEVRVALRAGGVNFHDVVVALGMVEDPRPLGGD
GAGVVVEVGPGTEGFAVGDRVMGLFNGTGPLVVTDVRMITRIPVGWSYAQAATTPSAFLT
AYYGLADLAGLRAGEKLLLHAATGGVGLAAVQLARHWQAEVYATAGPTKWHALRERGFDD
RHIASSRTLDFEERFRAAAGSVDVVLNSLAGDFVDASLRLLGPGGRFIDMGRTDIRDAEQ
VAVRCPGVAYRAFDLVGGAGPDRIQQMLAELSALFENGTLRPLPTTLWDIRRAPEAFRHF
SQARHIGKIVLTLPSALDPEGTVLITGGTGTLGAATARHLVAHHGVRRLLLISRRGLDTP
GATELAAELTGLGAEVSIAACDAADRAALAKLLETVPGRHPLTAVVHAAGLLRDATVEAL
TPDQLDEVLRAKADAAWNLHELTRDAGLSAFVLFSAAAGLLGAAGQGNYAAANAFLDALA
VHRHAQGLPATSLAWGYWAEATGMTGGMTDTDRARLARSGMVGLETEQGLALLDIALDSG
LPALAPIRLDLAGMRREAHADDLPPLFRSLVRGATPQAATGAAGPGGAAPAEAFAAMSEE
DRQQALLKLVRGATATVLGHDTADAIHPTQNFRELGFDSLTAVELRNRLGAATGLRLPAT
LVFDHPTPTAVVRLLRELLVPAGVTPTDSLLTGLDSLDTALTGGIADGERRARIAARLRE
LLRKVDGPWQGAEGDDPAEEDLASASDEELFQALDNELTVPSDDSLR
>A0A291T3K8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces malaysiensis|TrEMBL
MLNGSSDSGESIAQSGPDRDEGPGELPSLGPDFRDLPDLEQRRVLFDLVRAHVAAALRSE
SPRTLDAGSSFLDLGLDSLAAVNLHRGLVAATGLTLEVSLAYDYPTPSELVDHLHRQIVP
VATDEAAPARAVVGSDDPIAIVGMSCRFPGGVNSPEDLWKVVSEGVDAITPFPTDRGWDL
EALYSPDPDRPGTSYATEGGFIHDAPEFDAEFFGISPREALAMDPQQRLLLETSWEVFER
AGIDVTKLRGSRTAVFTGAEHHDYGPHLQSTKSGLEGYALTGIAGSVASGRISYTFGFEG
PAWTVDTACSSSLVSLHQAAHSLRQGECDLALATGVATMPTPGDFILFSRQRGLSSNGRC
KAFGAEADGTSWAEGVGVLLVERLSDARRNGHEVLAIVRGSAVNQDGASNGLTAPNGRSQ
QRVIRQALANAELTADQVDVVEAHGTGTSLGDPIEAQALLATYGENRPEGQPVWLGSLKS
NIGHTQAAAGAGAVIKMVMAMRHGILPKTLHVEVPTPHVDWSTGGLALLAEQRPWPETGR
PRRAGVSSFGMSGTNAHAIIEQAPPEEPLPATDADADEETASQPVSWLVSARSEEALRAQ
AARLREHVVRDRDLRPVDIGWSSAMTRAALEQRGVVVASDREGLLRGLAALAEDTDAPGL
VRGRSTAQRLAFLFTGQGAQRLGMGRELYETYPLFADVFDEACDYLEVRLGTSVLDVVFG
PENGADGADGEAAGDTAGDELNQTMFTQAGLFAFEVALFRLLESWGVRPDFLMGHSVGEI
AAAHVAGVLSLEDACALVAARGRLMQELPEGGAMVAVQASEQEVAESLEGREAQVSLAAL
NGPTSVVLSGDEDAVLELAGHWEARGRKTKRLRVSHAFHSPRMDAMLEEFGQIAACLSYS
APAIPVISNVTGDVAGAELATPEYWVRHVREAVRFDDGMRRLADQGVTTCVELGPDAVLT
AMGQDCLDAVGADAAFVPMARSGRAEAQTLAEAVATLYVNGVGVDWDAVYAGRGARRVSL
PTYAFQHKRYWLESGGAVTGDARSVGLGRVDHPLLGGLTELAEGDRTVLTGRLSLQTHPW
LADHAVAGGVLFPGTGFVELGLLAGIETGAGRLGELTLETPLLLPEQGGVRVQLVVGPAD
ESGVRPLGVYSRSDSDEPGEEWVRHAQGVLEADSGTAVTDSLLQWPVPGAEQVPMEGFYE
GLAQVGYGYGPVFQGLESVWRLDGDVFAEVALPDSAAQEAGRFGLHPALLDAALHAMEMG
DFGGESGRVTLPFSFTGVTLHAVGAGRVRVRLRPQGKDTVALLVTDTTGAPVASVESLVV
REVAPERFASGPRSTGGDGTLFRANWDVLAAARGGDRTADGVSTAVVGADRARVGELLAA
SGVEYAEYTGVDALVTALDGGAAVPDVVWAWCGAEPAGPDAGDIAEATRKATHRALALVQ
SWLAEDRFDGSRLVVVTRDAVAAGPGEGVAGLSNAAVWGLVRSAATENPGRLLLVDLDRH
AESATAAAGVVTAAMAVGEREVAVRTGQGLVPRLARNASGRVLEAPAGTSAWKLGTTGGG
TLDNLSLLPDPAAEAPLAPGYVRIAVRAAGLNFRDALIAIGMYPEDDATMGGEGAGVVLE
VGPGVTDLAPGDRVMGMINASFGPIAIADRRQIVPMPRGWTFAQGASVPVVFLTAYIGLV
EIGKLRAGESILVHTATGGVGMAAVQLARHLGAEVYATASPGKWDTLRAMGFDEEHFASS
RDLEFERRFMDATEGRGMDMVLDSLAREFVDASLRLLPRGGRFLEMGKLDVRDPEVVAAD
HPGVEYTAYDLVVADYDWVQRMLVELVELFESGALNPLPLTAWDVRRAPDAVRHISQARH
IGKNVFTMRRALDPEGSVLVTGGTGGLGSEVARHLVAEYGVRHLVLVSRRGPDAEGAADL
EAELAEAGASVTLAACDVADRASLERVLSAVPAEHPLTAVVHAAGVLDDGVIDTLSPKRI
DAVFEPKVDAAWNLHELTRTLDLAEFVMFSSVAGVFGSPGQGNYAAANSFLDALAAHRRA
LGLPAVSLAWGPWEQGGGMTGTLSQADMVRMAREGMAALSMAGGLRLLDAGRTSEDALLV
PMRLETSALSGQTDIPTLLRGVVRVRSKAASDGKAAAPESAKVKLAGLSGAELDRALLDL
VRGSAAMVLGHSGAQSIEPDRSFQNLGFDSLAGVEFRNRLNSATGLRLPSTLIFDNPTPA
ALAEYLRGRVATDGPAEPDVDPEEARVRALLASIPLERLRRAGLLDTLTELAGGKDQAEP
DAEEKETDSIDAMDDDDLIDMMLEDLDS
>A0A0L6Y2J5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Escherichia coli|TrEMBL
MDNAAIISGYSVWMPYAEDCSQLIDNLKQGKRVARTPWFTSNEEAIKCGFKGNPSVATLK
QVDDSALDLQSQLIDEALEQAMLDKHCLAGRNVRVYLTGIGPRIDGLDYKSFYNYNDVED
INLTQSITNLHASKMSQDTISSHLARKYRLQYLPPNMNCTSNSSLTAVHLATQGIEQGGI
DLAIVLNCSKIKTQDIWFLETQSMLDSEQVQPFGENSKGVAFAEGFSALLLESAHHRRAR
QQSEGVRVQTTYTQISAGRSNDASWLSTNVHKVMQAAMKQAEIALDDLAAILPHGNGSAV
SDNAEAKAITMFAGERQIPVLAYKGQIGYTATGSGVVDLIIGHHSLTHHQLIAPVGNDVI
IDSMASLVLTDGSVTNHSKRHLLKVGVGVDGSVIGVVMTNMQAGRAK
>A0A533QSF8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Candidatus Accumulibacter sp|TrEMBL
MTRRIAITGYSFRMPGTSTATYWQDLLAGRDLVGTVDPQRWALETFLHPRKDHPGTTYTF
AAGSIGDVTTFDAAFFGISPREAALMDPQQRLLLEMCWETLENSGIRPSRLRGSRCGVFI
GIASADYSYRMADDLAVADSTMATGNTASIAANRISYVLDLRGPSMAIDTACSSSLVALH
QACRAIASGEVSQALAGGISLHLHPYGFLGFAKASMLSPRGRCSVFDASADGYVRSEGGG
VFFLKDHDQAVADGDPILAIVAGSAVNTDGRKSGLTVPSADVQAALLEEAYAAAGIDPAA
IDYLEAHGTGTAVGDPIETLAIGNALGKRRAPGKPLPIGSVKSNLGHLETASGAAGLVKV
LHCLEHRLVPATIGISSVNPRIRASDWNIEVVTSNRPLPKTGKLTIGLNSFGFGGSNAHL
IIESPPQRRARGRPAATTGTLPPLLLSARSEQALKAAAGDFASFLAGQPPAAYYDIAHSA
AFRRDWLEQRLLVEAPTVPAITRALLDFAEDRGEATMASSGRMLSAASGPAFIYSGNGCQ
WSGMGRQLLADEPSFRDAVREVDTLFRRHADFSLIDELAGDNGDDRYDRTEIAQPALFAL
QVGITRLLQRQGITPKVVAGHSVGEVAAAWAAGALSLADAVEVIYERSRLQGTTRGLGQM
TAVALPQAAAASLLAELGLAGDLTIAGINSVRGLTIAGEQPALAALEDALTTRQVPWKRL
DLDYAFHSPAMDRLEAGIRQALAGIEPRASALPFCSTVSGSPLPGEDLGAAYWWRNIREP
VLFASAIDSLLDQGITIFVEIGAHPILRTNLNDCLKARSIDGRVIATGTRGDDGAQRIRS
AAREVAIAGAAVDWRTAFPKPGRFVRLPGYPWQRERHWHPVTSEALGLIHRHKIHPLLGY
PLAQHELTWENQLDTELNPVLADHVVGEATVLPGSAHAEMALAAALAWQPAAIVEIEDLE
IHSPLLLADDRSALVRLSIDPRDGKLAIRSREQLGTTDWTVHASARVVREAQDTLLREVL
PDLPQRPPDFDAEGHAALTRAIGISYGPSFQCIEHGWIDGRSALAALHIPPRVEAELVGT
HLHPALLDSAFQLLFQLLRQAIDADDAIAFIPTRFGRVILHSGHEGPPCFARATLLRRSA
RSLQAEFALFSPAGRVIAVVKDARFRGVRLSRSGRDRLRFLALHATPKPHAGRPAGPPAL
GFERVRSALAAVTQRAALKGTHRRYTEEVDPLLDSLCSRFTRRALQQIATEDGTLSAAAI
LSCQSASPDSAPFLADLLRLASDERSLAAAADGWAIVPDPREESSAEDIWNSLLADYPDY
FQIIHSVGRVGLHLPEILAGSSTLSEICPQESSLATLLLQVLGAHGRMKLGQALSALVTE
ALATLPAGQRLGIVEISEGAPALAMDICFALDFTRSDYCFASSSAAALEEAQVRLGEFFP
TIRTSLIDDARPADGNQEPAAGSCMMAIVMLDFPTTERALQALRHARRCLAGGASLIVLG
QHPSRWIDFVFGARRDGWSQSESGRWISSQRPGSFWQRQLQDLGCRCTDPCEFSPDTLSG
PYLLLAEVDEAAAAPVVAAEASVRSWILLADPVGYSARLADELARTLQARKDLVIQASTT
DTAALAALLRQTTTSYGALDGLVMLAGLAPASPTVSADETLTHHVERCALAARITQACEQ
SGTRTTCWLITGNAAAALLPPVAAEDDGSRAGPSDDAAFCGFARTMLNEAEPGSVRLIDL
ALPMSAQAAASLLDREFEKPDGELEIILTAAGQRYVPRLRDEPRPDARTPQILESPTVSL
GFQFAGQLRNLRWETHPRLAPAPDQVEVEVQASGLNFRDVMYALGLLSDEAIENGFAGPT
LGFEFAGVISRVGSNCTGFSPGDEVVGFAPSSFGNRVLTQGSAVAHIPPGISCEAAATIP
STFFTVYYALHHLARLQAGERVLIHGAAGGVGIAAIQIARWLGAEIYATAGSDEKRDFLR
LLGVVQIFDSRSLAFADQILEQSGGHGVDVVLNSLAGEAINRNFRVLRPFGRFLELGKRD
FYENTRIGLRPFRNNVSYFGIDADQLMLLHPELTRRLFGELMDLFSDGILHPLPYRSFEA
EDVVEAFRYMQQARQIGKIVITYHHGIKRVQPPQPGARRRLQLAADASYLVTGGLSGFGL
RAAEWLASKGARHLILISRSGPASAAAKAAIERLEEQGVRVHAAACDVTSRDALAALLDA
TGDDLPPLKGVLHAATAIDDALVRNLDDTQIRQVLAAKVLGARHLDELTRPRALDLFVLF
SSATAAFGNPGQAAYVAANTWLEALAAHRRSQGLCATAVGWGPIADCGFLARNEKVREAL
ENRLGGSALKSELALDVLEEMLLADRSGLAALDFEWQALSRVLPSAGSPKFGELAQQCGG
GDDDDQSQDIRRLLAELSDDELLVVIGDMLRSEIGEILRMAPEKIDANRSLFDMGLDSLM
GVELAVALDARFGIRLPVLALSQSPTITRLAERLLLQLRQTEGGARGGAGAAQEELVAQT
ELIARQQGVEVSAEEIARFAADFDATTPGDGTSGSDRHGA
>S7UV78|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii (strain ATCC 50853 / GT1)|TrEMBL
MAKPSPHSQPSIWSEKWAYHSSVPENDAVFKVPKKAWIIVGVPSQHMAEVLLSLKRMGLD
TSRVCGLGAISSMETLQNLVQGGTWAGMLVVSGLWATVSAVESLTETAHILRHYACLSTE
IEVPVLAVVTRGAQRSVVSPETFGQRERPTLESVPQQNQVFGHLEDEVPVHAGLLAFCRT
LRLEMGRCCRRFKPFLYFDTDRLHPRQSKESLDYHLGAVLKWLSRNDVPASFSEQIRPDS
DTLREWDIVIRKQSYFVPRVAPVLLKQPSTTAAGRIQKAKSYIVTGGLGGIGIVVASWLL
RQGAGRIFLWSRRGVPTDDVKETNQWCELNAAMETGRIQTVSCDVSEIEQVRHSIVLAVT
DSILGGIFHCAGTEGKGKLQDVSQQDIADVYASKVEGAWNLHRICSEMSINTNLDFFVLF
SSIAALPGNDAFATYAAANGCLDSLAEHRRSLSLPARSIQWGPWLDAGMAARTPSFERFM
RSRGIRGFHNEEAISHLETLLTADESLTCCAAVHVDWRIYAHIFGSHVPTWLQDVVPGLQ
TSLTPFSESNAPEQMHGSMDIQGVESAVIDVARRLCGAEGIVSASTEISSLGLDSLGAVE
FRNALQEALKIKLPASLLVEYACLKDIIQFIMENCFSDAARSTSDLVPLVTREPAANDQG
FAVVGMGCRIPKNATTTEEFWDMLLHEIDAVCEIPMDRFNIDAFYDPDPEQDKCYTREAA
LLDHPDFFDNTFFNLSDQEVLAIDPQQRVLLEVAYEALFEAGFTKEALLGKDFGVFCAAY
NNDFQFTNLTQGKATMCVFDKGEGRGRIPSLGEAAGYPEPGGFMCFIPNRISYSFGLTGP
SIGIDAACASSLVAFDAAVTKLKRGACSGALVGGVNIILSPTFFLGGCKAHQFSRAGRCK
TFDCNADGLVRGEGCGAAFLLPLDAARETGAFVHAVVRGSATCHYGRSSQITSPNTRALT
RVLRLSLQDASTAPSLVRYYEAHGTATVLGDVIEMSAVKDVFQTGRNAAAPLHMGTVHNN
IGHLDAAAGIVAFLKTVLCLKHRFVPANIHFKSLHPDIHGIDTQLIKYTRESHSIMTDDV
ATGVRKTIFGANLAYGMGGSVAAIITESGDEEADRRSLKAAPRHVWNHRRFPLNTQKFVY
LMGAMGQISMDDMPTPQSDVIHVMKRLSATALNVAFMRKLSPSTCAAGSIRSVFLTGATG
FIGSQVLFHLLQVKRQDPKLGTEDKKLTIYCLVRARDRAHGIYRIRDSLVGRGIEWKHEF
DQQVIPVIGNLEEGENMGLGPKQMQYLEQTVDAVYHAADYVNFAAPYDALRKSNVLSLIP
ILKLCTTYVAKPLHLVSNFAHHLQYFAGFSEDLNIAVDETVSPPLSPASIDRLEQQMPAG
IIGYPWTKWAVEEIIGRMKDVLHERCEEEGQRVSMEESEKNDILSKFQVTVYRLPNSCVY
YNNGYTNFANASLSLVLASAQERMIPPGVLPVGAPFLTTPVDLITGILVKLSMTEGKRHH
VYHLVSLRVARRKHVVQAIKWLFPDSVECTADELFRRIDENKENSPAHPLRAAMRFWRRY
WYSSDTDRDSPFPVAVNNVEDDLPGVMATFPSLADTWLRMASYCVKNYHMVRHPFTLAIS
FERLKKAIAGITKQRIDELALPSQTQELLNETCSTEDTTDIAAVKALVEHANLRKYDDCA
VSDVPDPRARA
>A0A7D3VZ04|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinomadura verrucosospora|TrEMBL
MGQERHTDFVSLVRENVREHGGRRAFTFVSEDAGPGRSYREDVLGFADLDRRARALACRL
EERGLRDRAVLLLYPEGLEFLSAFLGCLYARAVAVPAPLPALDAGRFDRTRRIIGDADIA
WILTDTAHREALETWLKEAGLAGRVQCLDTEAGEGDDPDAWTMPRYGPDTLAFLQYTSGS
TSDPKGVMVTHGNLLCNGEEIKRRIGGSADTVGVGWVPHYHDMGLVGQFLEPLYLGCRYV
FTSPITFIKRPALWLELITRHRGTITVAPNFGYELALRRVTDRQLEGLDLASLRTVKNGA
EPVRAATLERWCERFAPAGFEPEMWMPCYGMAETTLLITGAPSGPGPVIRDFDAAALARG
RAVPAGEGAARRLVSSGRPVTLDVRIVDPDGLVPLPDGRAGEIWVRGGSVAAGYWRSPAE
TRVTFQAYTAGGDGPFLRTGDLGFVDGGELFVTGRSKDLIIVNGRNVHAHDVEETAQAAH
PAALAGAAFVLDGVTTEDGREEVVLVQEISTRAAAGVPPGELAGRIKAAVARAHELPALS
VVLTGRGTVRRTTSGKMQRGLTRQALLDGLVTVLGADLEPAAAKFVRTEPSQKHD
>A0A7D3VSP8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinomadura verrucosospora|TrEMBL
MHGHGTTLIDLTPGRAGRVTLLCLPYAGGGTSAFHGWGDVLPDDVRVVAARLPGRESRLT
EPPLRDVRAVVAALAAEAGRLAAGPYAVFGHSMGALIGYELVRALRAAGRPEPECLVVSG
HSAPQCSGTVRRLHRLPDDELVAALRDYGGTPEALLSSPELMDLFLPTLRADFAVAETYA
HTPGPPLSCPMAVFGGERDAEVAPPALRAWAELTAGGCDLRVFPGGHFFVFENRDRVLAE
LAAILRRGRSASHAALPSGEAK
>I2C5F1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Bacillus amyloliquefaciens (strain Y2)|TrEMBL
MQNTEDLLYKLLAGQLKSVGFFTENETQPVMQGFYGRWLEESISILVQKGFLKQSGSTYV
LTGPIERADVLWQEWDEKKAPLLKDSSKQAMITLVETALRALPDILSGRVSATDVLFPDS
SMELVEGIYKNNETADYFNEVLADTLAAFIEERLKEDPNAEIRILEIGAGTGGTSAAVFK
RLKEYKHHVKEYCYTDLSKAFFMHAEKEYGPDNPYLTYKRFNVEEPPALQGIEAGAYDAV
IAANVLHATKNIRRTLRNAKAVLKKNGILLLNEISSHSFYSHLTFGLLEGWWLYEDAKLR
IPGCPGLYPEAWQSELESEGYRYVTFMAESSHHLGQQIVAAESDGVIRQKQPDAQAVEET
AASKEPADFTEPSFSVTDRTVQFIKETLAKSIKLAPERIQPETSFEKYGIDSILQVNFIR
ELETLTGELPKTVLFEHTNTKELAEYLLETYPDKLQQAFGAEQAPPETEHPEPAMNEPVP
LVTETRRFITEQKEPKAPKPETETVTVNRSDRDDIAIIGISGRYPESETLDELWEHLKAG
DSCITEAPENRWKSGLLKTMAKETRKEERKTRYGGFLQHIDAFDHHLFDIREDHVMEMTP
ELRLSLETVWETFENGGYSLERVNEWQESDSGIGVFMGSMYNQYFWNIPSLEKAALSSNG
GDWHIANRISHFFNLTGPSMGVTTACSSSLSAIHLACESLKLNSCSMAIAGGVNLTLEPS
KYDALERANLLEQGSESKSFGTGTGLMPGEGVGAVLLKPLSKAVADKDHIYGVIKSSALC
HSGGRQMYTAPDPKQQAKLMAASIDKAGINPETISYVESAANGSVLGDPIEVIALTNAFA
QYTDKKRFCALGSVKSNLGHLEAASGMSQLAKVLLQMERETLVPTINAKPQNPNIALEQT
AFYLQEKTEYWERLKDAETGDIIPRRSMINSFGAGGAYANLIVEEYISPNSDQSRHGDEE
YIFPVSAKTKWSFEAYLERLAAFLEKTPTLHPAAIASALQKRTHHSEYRAAFTAASVLEL
LEKLAAYRMDQRNLNFSDSDIGRRARQWEKGENIAFDQLRQEHAVHLPAYAFDHGTSFQF
GESENAAGVQAVYSDVDPYVKGHQFSGEPVLVGATYNSLAVDHFCDLFPEAEGGQIKKLN
YASPITVKKGDRIELKTESKQNGDAFELSIMHRSRTSPDWSIAAYAECSPYPFQKQHADL
AAIQRSYREVGRIDELYGDGTGTVVWGEEFKTITRLYKGSDAVLAKVNLNNSDSQQAHHY
AVNPLIANSAYLASLSLLDQTEAESYLPFGINSVTFSSPEDLTDCWLHIKLAKQTGEMIL
INADVISSRSEVVMRFEGYALKRFRPKTEQMNQPARTAVKNAGAPISSGSLTDDIRSYVL
GKLAKMMDEPAPSLPSDANIMELGLDSASLIGLTKEIGQEADIDVNPTLFFEYPTAEELT
RHFASAYKSKFSQLLADHKHSEEVRVTEAEERTLPKKQHPPCDNADIKQGIAIIGMSAQF
PQSPDIQSFWEHIVNGDHCITEIPADRWDWRRYAGDENDTSLRWGGFIDGVGEFDPLFFG
ISPKEASQMGPEQFLLLMHTWKAMEDAGLTNKALSSRPTGVFVAAGNSDPNNGTAIPSII
PNRISYALNLQGPSEYYEAACTSTLVALHRAVQSIRHNECEQAVVGAANILQSPKGFIGF
DSMGYLSKNGRAKSFQKDADGFVRSEGAGVIIIKPLEAAIEDGDHIHMVIKGTGVSHGGK
GMSLHAPNPAGMKAAMKKAYEDTDIDPQTVTYIEAHGIASEMADALEFNAIKAGYGESAN
QEESAPCYISTVKPCIGHGELASGLAALIKVVMAMKHHTIPGIPGFSAANEQMAIQKSRF
RFTEDNQEWTQLTDHTGRPIPRRAAINSYGFGGMNAHVVLEQYSPSHKDKESACEPQLIV
LSAKSEGRLKAAAGQLADFVQTGDTPSLRDIAYTLQTGREAMNCRLALVARNQDELLEKL
KEYRAFSEESNGMKSFFTGSQQTGSGDIGVLLEGTLGTVVTETLLAENNLEKLAFCWVKG
ADIPWDRLHQGKSVQRVPLPTYPFENHKYWNGGQSEDISLAPVSQNPQIRCESAADIVAD
ILGMEPAEMDQNKPLTEYGFDSISSIQLLKKLEGGDSRISLEALQKCSTVQEISMLLKTN
QSQEAGRNFPELVKLNDREKGRPVFWFHGGTGGVEAYQPFAKKSQRPFYGIQARGLTGKE
PLQGIEETAASYMRIIQAVQPKGPYDLGGYSLGGMLAYETARLLQEEGHTVKSAVMIDTP
YSEKWKERKPSVKSVMLQTINTMLTAYLKPENLEEALISREDITVQAEEEEVLKELIGLA
KKRGLPKSEEAIRMQLEQMMKTQLAYGMEEYDMKPLPHPEALQCYYFRNKSGLFLGDLER
YLTAEEEQIPLDHDAYWKEWERQMKQFHLLDVHSSNHVTMLSEPKPQNAIKAFCEKLYAN
KGTISANFLKSFRKKLDETNELVKR
>G4I0Q2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium rhodesiae JS60|TrEMBL
MSESETPETPDVPPRTDMTVQEMREWLRNWVANATGQGPDAIDESTPMVELGLSSRDAVA
MASDIEDLTGVTLTATVAFRHPTIESLATVIIEGEPEVEFDGDSEDWSRADGVEDIAIVG
VSTRFPGDMNTPDEMWTALLEGRSGISDLPEGRWSEFLSEPRIAERVAKAATRGGYLSDI
KGFDAEFFALSKMEADNMDPQQRMALELTWEALENARIPASSLRGADVAVYIGSSNNDYS
FLSLSDPSVAHPYAITGNQSAIIANRVSYFYDFRGPSVSVDTACSSSLVAAHHGVQALRS
GEADVALVGGVNALITPLVTVGFDEVGGVLAPDGLIKSFSSDANGYSRSEGGGMLVLKRL
SDARRDGDEILAVIAGSAINHDGRSNGMLAPNPDAQADVLRKAYKNAGINPRTVDYIEAH
GTGTILGDPIEADALGRVIGRGRAADQPALLGAVKSNVGHLESAAGAASLAKVALSLSRD
KVPPSINYAGPNPYIDFDDIRMRVADKVSDWPRYSGHAIAGVSGFGFGGANAHLVLREVL
PSDLAPPVADSEPVAEKAAADPNAGYVGGVRMDEYGEFVDEPLARRASDSDDDADDDEYA
ASASAFAEDAEPELPGLTDEALELIEAARAEWESAEKPVPVVPLAVSGFLTSRKRTTAAE
LADWVDSPEGRATSLEAIGRSLSRRNHGRSRAIVLAHDHDEAVKGLRAIADGKQSPLVYS
ADGPVTNGPVWVLAGFGAQHRKMGKSLYLRDPVFAEWINKVDAHIQDERGYSVVELILDD
AIDYTNETCEYPIEVVQTVIFALQIALGELLKHHGAKPAAVVGQSLGEAAAAYFAGGLSL
ADATRAICSRAHLMGEGEAMLFGEYIRLMALVEYSAEEIKTVFSDFPGLEVCVYAAPTQT
VIGGPPEQVDAIIARAESEGKFARKLQTKGASHTQQMDPLLGELAAELQGIEPHPLHTGY
FSTVHEGSYIRPGGEPIHDVEYWKKGLRHSVYFTHGIRNAVDNGYTTFLELAPNPVALMQ
VGLTTASAGLHDGQLIATLARKQDEVESMVAAMAQLYVYGHDLDLRTLFEAGDFAHIPPT
RFKRKPHWLDAQFTGDSSVMMPGNHVATPDGRHVWEYSPKGQTDLAALVKSAAAQVLPDA
KLTASEQRAVVGDGARLVTTLTRHPGGASVQVHARIDESFTLVYDAVVTRGGAVSALPSA
VATGTAVSAPAVAAVEEDDDADILSDNLTAGAGLAAGFAKWSPDTGETVHDRLAAIVGGA
MGYEPEDLPWEVPLIELGLDSLMAVRIKNRVEYDFDLPPIQLTAVRDANLYAVEKLIQYA
IEHRDEVEELAETQKGKTAQEIAAEQAELMGGASTVAELEAKLAEAGHPIATESEPTIPP
PPTDPAGPGPRASEATGEAKSTAAAAAAKVLTQEAVAEALGADVPPRDAAERVTFATWAI
VTGKSPGGIFNELPALDDAAATKMADRLSERAEGVISVDEVKSAKTIEALSTIVRAQLEE
GVVDGFVRILRAPQEGSAQTPVFVFHPAGGSTVVYEPLMKRLPADTPIYGLERVEGSIEE
RAAEYVPKLMEIHGAGPYILTGWSLGGALAYACAVGLKRNGCDVRFVGLIDTVRAGEEVP
QTKEEIRARWDRYALFASRTFNVEIPEIPYEQLEELDDEGQVKFVLDAVKQAGVDIPGGI
IEHQRTSYLDNRALDTANIEPYEGHVVLYMAERYHDDAIMFEPRYAVRQPDGGWGQFVAD
LEVVPIGGEHIQAIDEPYIAKVGAHMSEAINRIDAEEKQDQ
>A0A3S4CWJ7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium basiliense|TrEMBL
MNSRYEAFDQSVENYWLTSTEGSVLSGRLAYVFGFVGPALSVDTACSSSLVALHEACKRC
VWRMRWRWPVE
>A0A086PNW5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii MAS|TrEMBL
MAKPSPHSQPSIWSEKWAYHSSVPENDAVFKVPKKAWIIVGVPSQHMAEVLLSLKRMGLD
TSRVCGLGAISSMETLQNLVQGGTWAGMLVVSGLWATVSAVESLTETAHILRHYACLSTE
IEVPVLAVVTRGAQRSVVSPETFGQRERPTLESVPQQNQVFGHLEDEVPVHAGLLAFCRT
LRLEMGRCCRRFKPFLYFDTDRLHPRQSKESLDYHLGAVLKWLSRNDVPASFSEQIRPDS
DTLREWDIVIRKQSYFVPRVAPVLLKQPSTTAAGRIQKAKSYIVTGGLGGIGIVVASWLL
RQGAGRIFLWSRRGVPTDDVKETNQWCELNAAMETGRIQTVSCDVSEIEQVRHSIVLAVT
DSILGGIFHCAGTEGKGKLQDVSQQDIADVYASKVEGAWNLHRICSEMSINTNLDFFVLF
SSIAALPGNDAFATYAAANGCLDSLAEHRRSLSLPARSIQWGPWLDAGMAARTPSFERFM
RSRGIRGFHNEEAISHLETLLTADESLTCCAAVHVDWRIYAHIFGSHVPTWLQDVVPGLQ
TSLTPFSESNVPEQMHGSMDIQGVESAVIDVARRLCGAEGIVSASTEISSLGLDSLGAVE
FRNALQEALKIKLPASLLVEYACLKDIIQFIMENCFSDAARSTSDLVPLVTREPAANDQG
FAVVGMGCRIPKNATTTEEFWDMLLHEIDAVCEIPMDRFNIDAFYDPDPEQDKCYTREAA
LLDHPDFFDNTFFNLSDQEVLAIDPQQRVLLEVAYEALFEAGFTKEALLGKDFGVFCAAY
NNDFQFTNLTQGKATMCVFDKGEGRGRIPSLGEAAGYPEPGGFMCFIPNRISYSFGLTGP
SIGIDAACASSLVAFDAAVTKLKRGACSGALVGGVNIILSPTFFLGGCKAHQFSRAGRCK
TFDCNADGLVRGEGCGAAFLLPLDAARETGAFVHAVVRGSATCHYGRSSQITSPNTRALT
RVLRLSLQDASTAPSLVRYYEAHGTATVLGDVIEMSAVKDVFQTGRNAAAPLHMGTVHNN
IGHLDAAAGIVAFLKTVLCLKHRFVPANIHFKSLHPDIHGIDTQLIKYTRESHSIMTDDV
ATGVRKTIFGANLAYGMGGSVAAIITESGDEEADRRSLKAAPRHVWNHRRFPLNTQKFVY
LMGAMGQISMDDMPTPQSDVIHVMKRLSATALNVAFMRKLSPSTCAAGSIRSVFLTGATG
FIGSQVLFHLLQVKRQDPKLGTEDKKLTIYCLVRARDRAHGIYRIRDSLVGRGIEWKHEF
DQQVIPVIGNLEEGENMGLGPKQMQYLEQTVDAVYHAADYVNFAAPYDALRKSNVLSLIP
ILKLCTTYVAKPLHLVSNFAHHLQYFAGFSEDLNIAVDETVSPPLSPASIDRLEQQMPAG
IIGYPWTKWAVEEIIGRMKDVLHERCEEEGQRVSMEESEKNDILSKFQVTVYRLPNSCVY
YNNGYTNFANASLSLVLASAQERMIPPGVLPVGAPFLTTPVDLITGILVKLSMTERKRHH
VYHLVSLRVARRKHVVQAIKWLFPDSVECTADELFRRIDENKENSPAHPLRAAMRFWRRY
WYSSDTDRDSPFPVAVNNVEDDLPGVMATFPSLADTWLRMASYCVKNYHMVRHPFTLAIS
FERLKKAIAGITKQRIDELALPSQTQELLNETCSTEDTTDIAAVKALVEHANLRKYDDCA
VSDVPDPRARA
>A0A099L5V5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Colwellia psychrerythraea|TrEMBL
MNTETTELSSETDIAIVGLSGRFPGAENVDVFWQNLKNGVESIEQYNEETLRDMGVSEDK
ISDPDFVACGALLPDQDKFDAAFFGYSPREAEELDPQQRLFLETAWQAMESAGYHGDACD
FPIGVYGGCGVNTYLITNLMQSGRFNDLGNISSLQALMNGNNKDAMTMTLAYKLNLKGPA
VTIQTACSTSLSAIHMACRSLLNHEADMTLAGGAWLNLLHEGGYVYQPGAILSPDGHCRP
FDEQAQGTIIGSGSGVVALKRLEDAIADGDTVYAVIKGSAMNNDGNTKAGYTAPSVDGQA
EVIAAAQEMADTPPETISYIEAHGTGTVLGDPIEIAALTRAFRLGTDKNQYCAVGSVKSN
VGHLDAAAGVTGLIKTVLSLKNGIIPASLHYKKANSEIDFDNSPFYVANKTMPWTNENGP
RRAGVSSFGIGGTNVHVILEEAPKQPNIAPQRNWQILPLSAKTSSALTNQQANLAEWLEK
MPAEQWQNAAYTLQVGRKGFNHRSFVVAQNSNQAKGALIADASPLRVQSHSMVDSNRPVV
FMFPGQGSQHINMAQSLYGSEAVFKAEFDRCRQGFQPHLDLDIAELIFVDDNQAENAAEQ
LKQTALTQPVLFAVEYALAKQWQAWGIKPNAMIGHSIGEYVAACLAGVFSFADTLKIVAQ
RGLLIQAQPSGSMLSVALSEKKLVAYLQSGCELASVNGPENCVISGTDSAISAAEATLTA
AGIAVQRLHVSHAFHSSLVAEAGNGLAALIADLPRKTPNIPFISNVTGTWITDQQATDPE
YWSAHLTQTVRFHQGLRTLVATQNFVLLEVGPNNVLSQLAGRDPKVKEQASVVTSLPHVR
KNTEEAQHVTTTLGRLWLEGVNIDWTSLYTEAPRRIALPTYPFERKRFWVEAQPEAFNTL
QNNNLGIVAKPLENWFYMPSFKRCLSSPIENPSLGGTLLFIDDHDISQTLINKLTNDAEF
LVCLRLGDAFKQTSENEFIVRATDGEDYQQVLSTVNKTHGSVTQIFHTWSLSVSNTTSFE
QTQERGLLSVLTLVQALETIQIGKNVQLSLITKGMLDVSGHDDVLPQQTTLLGACKVIPQ
EFPNIHCRLIDFGTHFNATWLDWLVTDIAADDDLVLAYRHHNRWQLTYEALAKPVQDKAV
YRQKGVYLITGGLGGIGSVVAEHLATTVQAKLVLLGRNSPNEKQQTWLTKLEGLGAEVMF
CQADVANKNQIQQIISEALARFGEINGVIHAAGNGATNLISATDRNFVDDMFAAKVSGTQ
LLLESLANQQLDFIVLCSSLASIAGGLAKGAYAAANAYLDGIAQRYAQQNNFPVIAVNWD
SWREVGMAANMEMPDNVGITPTQGLEVMQRILSAPVVPQILISTVDLHTRIQATKGNILV
ADLAMPIAEPRSEEYARPDISTPYIAPEDELQQGIAEVWTGMLGIKEVGIHDNLFELGGD
SLMGVQMLSKVRSLYEVDLPPASFFKEPTVLGLAQLVTTLLIQQLEQEVNTQELA
>A0A0C5PRK7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pelosinus fermentans JBW45|TrEMBL
MKDNENQSSVEKDQEDLQSKPSQEKLMDIAIIGMASRFPGAKNYEEFWENLKQKRSSVQE
IPLERWNWEAFWGDPKTEINKSNSKWGGFIEDVDAFDAGFFSLSPRELEALDPQQRIMLE
LSWTCLEDAGVCPSHVSGKKVGVYVGVFNFDYKELQERTFRTIETHHSIGTAAGVIANRV
SHYLNLKGPSFTVDTACSSSLTAIHVAMQSLHSGECSMALAGGINLLLTPTRHISFSKAG
LMSPTGSCKAFDEGADGYVRSEGAGVILLKPLEKAIEDGDYIYAIVKGSAINHNGKTHTL
TYPSSDAQADVIVEAHKQARVAPESISYIETHGTGTPKGDPIEFQGLLKAFERLYSEGNQ
SLIRNYCGLGSAKTNIGHLEAAGGMAGVIKVVLSMKYKQLAGLQNFKRLSHRISIENSPF
YVVDQLQEWKLLKDENNQAFPRRAGVSSFGFGGTNGHLVLEEAPNIVRHSKRKFPYSLIC
LSAKTEEALRNKEEDLLHWLEEKGQENKLIDISATLLLGRDHFEIRSAFVVKNVQELQKK
LKQVLEKEEAEGYFKESNARKEKETQSSFEESGKMILTELHLNKLKDEHEYGSKLMALAE
MYANGNDLDWKMVFPEGKIQRLNLPTYPFARERYWISDSDIESDTRSINLALIHPLLHEN
TSDLSEQRFSSTFTGQEFFLADHVVKGQRILPGVAYLEMARAAVKQAAGALAEGQTGIRL
KNVVWSRPIAVGDQPIPVHIGLFPEDGAIGYEIYTEPEGVNAESIIHSQGIAKLCSFAEP
PILDLPALQAECNQSILNSDQCYKALRTVGLDYGPGHQGIEKLYAGSGQVLAKLSLPSFV
ADTRDQFILHPSLMDSALQASLMMNSSDFKLALPFALQEVEIIEKCISDMWALIRYSEGS
KAGDKVQKLDIDLCDEQGMVCVRMKGVSSRVPPATLGALLLHPYWKEQAIAQEAAAPTYT
QHLVMLCETNKISQAMIESQMNGVRCLTLESQQSGIEERFQIYAVQAFEEIQSILKEKTK
GNVLIQIVISTQQEQQLFSGLSGLLKTAQLENPKFIGQLIEVESGEDAEGIVEKLKNNSQ
SLIDNHIRYQDNKRYVIGWNEVEALKEAVKIPWKDQGVYLITGGAGGLGLMFAKEIAHKV
KGAILIFTGRSPLDEDKQSKIRELESLGTLITYKQVDVTDKQAILDVIQSIQKNFGRLNG
IIHSAGIIRDNFFIKKTKEELEAVLAPKVTGLVNLDEATKDLNLDFFILFSSITGALGNL
GQADYATANAFMDAYAGYRNSLVALEQRQGQTLAINWPLWKEGGMHVDIETEKMMIQNWG
AIPLQTTTGIGALYQGVASGKTQVMVLEGELKRIDEIFLGQLPRREAAETSSIIAEDKAV
AVISPDLLQEKAINYFKKLLSSVIKLPVNRIEANASMEKYGIDSIMVMQLTNQLEMIFGS
LSKTLFFEYQNIQELTGYFLESYRDKMIGLLGIEGKTQVLAADLKASVAVTEPIETAISS
RRRARFASLCRETEFPQEKAGASDIAIIGVSGRYPQAKNIQEFWNNLRDGKDCITEIPKD
RWDHNLYFDEDKNKQGKTYSKWGGFLDGVDQFDPLFFNISPREAEIMDPQERLFLECVYE
TMEDAGYTREGMNHDLGVKGNVGVYVGVMYDEYQLYAAQEQIQDRPVSVWGNPSSIANRV
SYFCNFHGPSMAVDTMCSSSLTAIHLACQSLQRGGCELAIAGGVNISIHPNKYLFLSQGK
FVSSKGRCESFGQGGDGYVPGEGVGAVLLKPLSKAIADGDQIYGIIKATTVNHGGKTNGY
TVPNPNAQASVIGRAIKEAGINPRTISYIEAHGTGTSLGDPIEITGLTKTFQEYTKDKQF
CAIGSAKSNIGHCESASGIAGVTKVLLQLKYRQLVPSLHSETLNPKIDFANTPFVVQQKL
AEWRRPVLEICGESREYPRIAGISSFGAGGLNAHVVIEEYIPQDLRRSQTTINSQNPAII
VLSAKTEDKLKEQAQQLLAAIGEQQFSDENLLEMAYTLQVGREVMEEHLAVIVGSIKELE
GKLKDFLAGQDGIEDLYRGKVKRNKELLAVFAADEDMEKTIDAWIRKGKYDKFLELWVNG
LIFDWNKLYGDSKPHRISLPTYPFAKERYWVPKIDTAVSSKINKDIRALIHPLLHENTSD
LSEQRFSSTFTGQEFFLADHVVKGQRILPGVAYLEMARAAVKQAAGALAEGQTGIRLKNV
VWSRPIAVGDQPIPVHIGLFPEDGAIGYEIYTEPEGVNAESIIHSQGIAKLCSFAEPPIL
DLPALQAECNQSILNSDQCYKALRTVGLDYGPGHQGIEKLYAGSGQVLAKLSLPSFVADT
RDQFILHPSLMDSALQASLMMNSSDFKLALPFALQEVEIIEKCISDMWALIRYSEGSKAG
DKVQKLDIDLCDEQGMVCVRMKGVSSRVPPATLGALLLHPYWKEQAIAQEAAAPTYTQHL
VMLCETNKISQAMIESQMNGVRCLTLESQQSGIEERFQIYAVQAFEEIQSILKEKTKGNV
LIQIVISTQQEQQLFSGLSGLLKTAQLENPKFIGQLIEVEPGEDAEGIVEKLKNNSQSLI
DNHIRYQDNKRYVIGWNEVEALKEAVKIPWKDQGVYLITGGAGGLGLMFAKEIAHKVKGA
ILIFTGRSPLDEDKQSKIRELESLGTLITYKQVDVTDKQAILDVIQSIQKNFGRLNGIIH
SAGIIRDNFFIKKTKEELEAVLAPKVTGLVNLDEATKDLNLDFFILFSSITGALGNLGQA
DYATANAFMDAYARYRNSLAALKQRQGQTLAINWPLWKEGGMHINEDAEKMMMQNSGLIA
LETTTGIEALYQGVSSGKDQVMVIEGDIERLHTAFLGQPSVTGGAKISVIVDEKKVVPTI
GQDLLQEKALNYFKKLLSAVIKLPTDRIEADAPLEQYGIDSVMVMQMTNQLEKYFGSLSK
TLFFEYLNIQELTGYFLISYRDQLTELLGVDEKAAATIENSTELITEAETVKAIFNSRKR
PRFTSLPIGSPEEKTSSALDIAIIGVSGRYPQAKNVKEFWNNLQNGKDSITEIPKERWDH
SLYFDEDKNKQGKTYSKWGGFLDGVDQFDPLFFNISPREAEMIDPQERLFLQCVYETLED
AGYNREVLGIHQGFGLEGNVGVFVGVMYEEYQLYGAQEQIQGRAIALPGNSSSIANRVSY
FCNFHGPSMAVDTMCSSSLTAIHLACQSLQRGGCEFAVAGGVNVSIHPNKYLMLGQGKFV
SSKGRCESFGQGGDGYVPGEGVGAVLLKPLSKAIADGDQIYGIIKGTAVNHGGKTNGYTV
PNPNAQASVIGRAIKEAGINPRTISYIEAHGTGTSLGDPIEIAGLTKTFQEYTKDKQFCA
IGSAKSNIGHCESASGIAGVTKVLLQLKYRQLVPSLHSETLNPNIDFANTPFMVQQELVE
WKRPIVELDGEKREYPRTAGISSFGAGGSNAHVVIEEYISKDQQRPSIMITTQNPAVIVL
SAKNEERLHEQAQQLLTAIGEQESSELGLANIAYTLQVGREAMEERLGLIVGSSKELEEK
LKSFLAGQKGIENLYRGQVKRSKENLVVFMADEDLQKAIEAWINKGKYGKLLDFWVKGLI
IDWNKFYGNVKPHRISLPTYPFAKERYWIPKTSNYPASNTITAISGPIIGPIHLLLHQNT
SNFSEQRFSSTFTGQEFFLADHVIKGQKVLSGVACLEMARAAVEQAVGVLKESQLGIRLK
NVVWTQPIVVGEQPVQVHIGLFPEDDGLIAYEIYSETKADSADPIVHSQGTAVLSEILEV
PTLDIKTLQAECSRDILASHQCYDAFRAMGFDYGPGHQGLETVYVGQRQVLAKLSLSSLF
SSTKDQFVLHPSLMDAALQASIALIIGSGNLKTILPFALQELEVFSRCTPAMWALVRYCN
DSKAGDKLQKFDIDLCDEQGLVCVRMKSFSARVLEDEVGLLGTTAALGSLMLKPYWKEQI
LVQEVIVPDYEQHFVVLCEANEDLKESIENLIDGVRCISLESKQNNIAERFQTYTVQVFE
NIQSILKKKNKKNILIQIVVPSRGEQQIFSGLSGLLKTAQLENPKLIGQLIEVGLEEDSV
EIIKILKENSQCPLDNHIRHEEGKRYVAGWKEVEISQEEVNLPWKDKGIYLITGGMGGLG
LVFAKEIADKVKDVTLILTGRSLLNENKQTKLKELETLGARIVYKQVDVTEKQAVVELIQ
SIKDNFGNLHGIIHSAGVICDNFIFKKTNEELEKVLSPKVTGVVNLDEATKDLDIDFFVL
FSSVSGALGNLGQVDYSTANAFMDAYSRHRNDLEMLNQRHGRTLSINWPLWQEGGMHVDQ
QTEKMMQQNMGMIPIKTPTGIQAFYQILASENNQMMVWEGDNVQLRHYMKTILRNFEQLQ
RNTENDDHDNSATNGNIAEINDEFYSNVFEKIAKGKLSKEQFINSVVSGKGA
>A0A2N9BJI6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces chartreusis NRRL 3882|TrEMBL
MAASNDSVVRALRASMKQNERLQRENNRLAEAAREPIAIVGMACRFPGGVASPEDLWRVV
ADGVDATSEFPADRGWPEDLYDPDPDASGKAYARRGGFLDDVAGFDAEFFGISPREALAM
DPQQRLLLEVSWEALERAGLKAEQLRGSSTGVFIGGATSAYISDLNRVPDSVEGYSLTGN
TLSVLSGRVSYFLGLEGPSVTVDTACSSSLVALHLAVQALRQGECSLALAGGVTVVASPT
GIIELSRQRALAQDGRCKAFSASADGFSAGEGVGVLAVERLSDARRNGHRILGVVRGSAV
NQDGASSRLTAPNGPSQQRVIKAALENAGLQPQDVDAVEAHGTGTKLGDPIEAQALIATY
GKDRPEGRPLWLGSVKSNIGHAQAAAGVAGVIKTVMALRNDMLPPSLYAGDPTPMIDWND
GDVSLLSEGVAWPRGERVRRAGVSSFGISGTNSHVIVEEAPAEECVDQPVVPVVDGGSGL
VPWVVSAASVGGLRGQVERLVSFVGERPGVDVAGVAAGLVGRAGLRRRLAVVGGSVGELV
AGLESVVGEGGVVAREGVRVGLLFAGQGAQWAGMGRDLYEGSSLFAGVVDELCGVLDGLV
GGSVREVMFGLGGVEGLLDQTVWAQAALFVLEVGLFRLVESWGVVPDVVVGHSVGEIAAA
HVAGVLSVEDACVLVAARGRLMQGLPVGGAMVSVAAGVEVVEPLVVAAGAGVAVAAVNGP
ASTVVSGDADAVGVVVAACEERGFRTRRLRVSHAFHSARMDPMLDEFRSVVEGLGFGEAR
FGVVSTLLGRVAGPGELGRPEYWVRQVREPVLFAAAVGEAVRAGVGAFVEVGPGGGLTAM
ARECVGDGEVVLVPLLRKGRGECASVLGAAGRLWEQGVEVDWRAILPPVPAVELPTYAFD
HTPYWLEQETAAPGDPVEREFWDLVESQDVGQLSALVGLDDDGRSAAGAVLPALSSWRRR
QRQSGRLDARRYRIDWKPVAVGTPELSGTWLVVVPAGLDDAEPVSGCVRAITRHGGEVRR
LAVDAGSGEARDALRAALRDAATGTPEIAGVVSLLGLCEAPVPAHPELPAGVAGTVLLIQ
TLAETGIDARLWSVTSGAVRATDDDGPVRPEQAPVWGLSRVAALEEPKRWAGLIDVPPAL
DDRAGERLAAALAGIGDEDQVAVRGDGVLARRLVRAPLGGAAPVRDWRPTGTALVTGGTG
ALGGHAARWLAGHGAAHLLLVSRSGPEAPGARELRDELTATGAEVTIAACDVSDRAALAE
LLAGIPAEHPLTTVVHTAGALGSGAALLESDLPGIAEVFAGKVAGAVNLHELTADTPLDL
FVLYSSNAGVWGGTRQAGYAAANAYLDALAEHRRAHGLPATAVAWGAWAGSGMAGDEEAV
EWLGRSGMRTLDPETGLAALHQAVRHDETFVAVADLDWQRFAETYHAARPRPLIAEIPEA
RRAEEEPAAEQGPAPLARLVAETSAARGPAVLFEALCTEVAAVLGHTTVAEFDRELPFGD
LGFDSLTGVELRNRLAAATGLSLPTTLVFDHPTLGALAEFLLGRLQPQQAEEAAPALGEI
HRLEQLLGTLADTDDRDEITGRLETLLWNWRRSAYGDDPASVPLGSASPDAVSLDTVSVD
SVSDEDIFGLIDKELGDD
>A0A0U0ZQB3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus|TrEMBL
MTAVHVDPVVISGMAIEAPGGIDTPAAFWNALADGRELISAFPRDRGWPVDELLSLSNLD
GWGRISDAGGFITDASAFDPTFYGITQREAVAMDPQQRVAMRVAWKALENTGLNPGAVDG
SEAGCFIGISPNEYGPPVGEVNAHSGMRVVGRGQLGAAGRISHGLGLIGPSVCVDSACAS
SLAALHIAASAVRADECEWAIAGGVCVMGSPGGFYEFSRMHALDPDGHCRSYSDEANGTL
WGEAVGMVVLERESRARALGHRVYGRIMAVRTNHNGGGKPILVPRGRAQAKLVAATIAAS
GVDPADVGMLEGHGTGTRAGDPLEILALQSTYGAGGSNALLGSAKSNAGHAQSAAGMVGL
IKLLLSGQYGHIPPTLFADNPTTKIDWSMTGIRLATKLHPWEPKDGIRYGAVSSFGAGGA
NAHAIIAMPAMDTQGEDGDDF
>A0A6C0QDT2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. S4.7|TrEMBL
MADEGKLRDYLTRVIAELHQTRQRLHDAESQEHEPIAIVGMACRFPGGVRSPEDLWRLVA
DGRDAVGGFPTDRGWDIESLYHPDPDHPGTSYVREGGFLEKAADFDADLFHMSPRETLAT
DPQQRLLLETAWEAFERAGINPQSLHGSRTGVFTGVMYNDYSSRLMHQVPAGFEGHVGNG
SAGSIASGRVSYAFGLEGPAITVDTACSSSLVSLHLAAHALRQGECTLALAGGVTVMATP
GTFVEFSRQRGLAPDGRCKPFAAGADGTGWSEGVGLLLVERLSDAKRNGHQVLAVLRGSA
VNQDGASNGLTAPNGPSQQRVIRQALVNAGLTPADIDAVEAHGTGTALGDPIEAQALLAT
YGEGRSEDAPLWLGSLKSNIGHTQAAAGVAGIIKMVMAMREGVLPRTLHVDEPSSHIDWS
SGTVRLLTEQQDWSHPDWPLRAAISSFGLSGTNAHVVLEQAPAIAPVEGETEPSESGSSG
VVVWPVSGHTAPALAAQAAQLHAWLEDHPDADLPAVADALGRTRATLDHRAVVFGTERGQ
LLDALAGIAAGTPTPHGVTGRYQAGKLAVLFTGQGSQYPGMGHGLYTTHPVFRDALDEAC
AALDPHLPVPLLSVMFAGPGTPEADLLHHTTHTQPALFALETALYRLVESYGVRPDALAG
HSIGELTAAHAAGVFTLTDAAVLVTTRARLMGELPAGQGTMLTLHTTPDHITPLLEGTTL
EIAARNSPTNTVVSGTVSDIETLTARAAEAGIRTRALNVSHAFHSAHMDPVLDTFRTTLT
TLNPQPPTLPVISNRTGQPLTPEQALSPDYWTEQLRHSVNYTDITHHLDTTGTTTYLELG
PDTTLTTLTTQTLPDATAIGTLHPKHPHHHTLHTALATLHTHHTPLTWPTTTHPTHHHPT
LPTYAFQHHHYWLNAPANSGDPASLGLRRTAHALLGAAVELADGGSAVTFTGSLSLRTHP
WLADHAVAGAVLLPGTAFVDLALHAGEHTGHPHLAELTLQAPLVMAETGSVHLQVTAGAD
EDGSGRRPVTVHSRAEDGESWALHATGHLTTTPPAPAEDLTVWPPAGAEALSVDTLYDDL
AEHGYHYGPTFRGLTAAWRSGDSDDVYAEITLGEDADPDGYGIHPALLDATLHALGLAPG
TDQQDEDGYENGKAQLPFSWSGVDLHATGASALRAHVRRLTPTTARITLADPEGQPVGHI
DTLTLRPLDVAQLHRAGESDPYRDTLFSLDWSPVPLPEAGAGSSGQYAVLAPLADGSSSD
DNSTNHAAEFAASLAAAVGCEGTTDLDRLAEGDEVPATVFLPVMDRGMHADDEPVPARVR
QLGTRLLALVQRWLRDESLAAVRLVVVTSGAVAAEPGDPVSDVVSASVWGLLRSAQSEHP
DRFLLVDVDGEPESAAALPAVVLSGEPQVAVREGRPLAARLGRYSTKEALAVPAGASDWS
LGVTGQGTLDHIALVESPEASAELAPGEVRVAVRAAGLNFRDVVVTLGMVSDVRAVGGEG
AGVVLEVAPDVTHLRSGDRVMGLFTSTGPVTVTDARLLTRIPQGWTFAEAATVPIVFLTA
YYGLVDLAAIEPGERLLVHAGAGGVGMATLQLARHWQVEILSTASTGKQHVLRAHGLDDA
HIASSRTLDFEEHFRASTEGAGVDVVLNSLAGDFADASMRLLSDGGRFIEIGKTDIRDSE
AVAEAYPGTVYQAFDLGDAGPERIQEMLEELRTLCEEGVLSPLPVTAWDIRRAPEALRYL
SQARHIGKVVLTLPSALRAEGTVLVTGGTGTLGALTARHLITEHGARHLLLTSRSGPDAG
GARELQEELTALGADVRIAACDAADREQLTALLDTIPAEHPLTAVIHTAGVLDDATVDRL
TPEQLTAVLAPKVDAAWNLHQLTAESDLDAFVLFSSAAATFGAPGQANYGSANVFLDTLA
AHRHRRGLPAASLGWGLWAESSGMTQHLDGADVARVSRAGVVPLTTPQGLALLDMGLAEN
RPFLLPTGLDTRALGSTAPPPLLRALVQPRRASVSRAARGSGASTGKGGSLAEALSLLAP
EQRERHLLDLVRSHVATVLVRGDAAAIEADRTFRELGFDSLTAVEVRNRLTASTGLQLPT
TLIFDHPTPILAARFLLTELLGTLPATAIGAAAPIAHDEPIAIIGMACRFPGEVSSPEDL
WELLAEGRDGIGDFPTDRGWDIERLMDPDPERTGTSATSSGGFLYDAAKFDPELFRISPR
EAVATDPQHRLLLETSWEAFERAGINPMSLQGSDTGVFAGVISQDYLSRLTDTPKGFEGQ
VGIGSALSVASGRVSYTFGLEGPALTIDTACSSSLVALHLACQSLRNGESSLALAGGVTV
MAAPGCFTEFTRQGGLAPDGRCKPFAASADGTGWSEGVGLLLVERLSDAKRNGHQVLAVV
KGSAVNQDGASNGLTAPNGPSQQRVIRQALANAGLSAADVDAVEAHGTGTALGDPIEAQA
ILTTYGQDRPEDAPLWLGSLKSNLGHTQAAAGVGGVIKMVMAMREGVLPQTLHVDEPTPH
VDWSAGAVELLTENTPWSVEGERPRRAGVSSFGMSGTNAHVILEQAPAAEPVETTETDDP
AESPSGVLVWPVSGHTSDALGAQASRLHAYLAAHPEVTAEQVAHALTTTRAALTHRGAVV
ATEYAELMEGLAALGEGAPSAHVVSGVTRPQGKTVFVFPGQGAQWPLMTADLLTTEPVYA
QSIDACAKALAPYVDWSLRDVLTDPAGELLERVDVVQPALFAVMVSLARLWEHHGTSADA
VIGHSQGEIAAAHIAGALSLEDAAKIVALRSKALTTLTGRGTMASVTLPHEQVTEQIAGY
DSLSVAVINSPTHTVISGTTEDIHTYLDHCQANNVQTRLLPVDYASHSPHVEALEAELLT
ALADIVPQAASIPFHSTTHPIDRPTDTTTLNSTYWYDNLRRPVHFHTTLTHLNNTGHTTY
IETSPHPTLTTPINQTNENPETGNGNDTPLTVTGTLRRHQYGPTQFRLAQATLHTHNTPT
TWPTPTTQPTTLPTYAFQHQHYWLNDTPTQANLTTAGLTPANHPLLAATIQHPDNHTTTF
TGTLSLRTHPWLADHTVTGTILLPGTAYIDLALHAGHHTNHPHLTELTLQTPLTIPENET
IQLQLIAGPEDTQQQTTPISIHSRRVTDEAWTLHAIGVLSDVPADSAGTDLTAWPPAGAK
ALSVETLYESMDARGYGYGPAFRGLTAAWRDGDNLYAEIELDPDTDVTGYGIHPALLDAA
LHTLGADSGTDSGTDGRAEAELALPFSWSGVSLHATGATALRVHIGRGDARTLALSIADP
VGQPVVHVEALTLRAIDPAQLAAVSTGPADENRLFTVAWSPAVPSEAGTEAVANGVANDA
DPQPYALLLAGVDEAPQEVEVHARLGDFAELPLPERVQATSEQALALLQDWLTDDARTNS
HLVVLTRHAVAAQPGEHLTDLTHAPLWGLIRSAQSEHPRRITLIDTDNHPDSTNHLTQAI
HTATITDEPQVALRNGNILTPRLTPFPTPERLSPPADAPAWRLGVTGGGTVEDVRLVDFP
EAVAPLAPGQVRIALRAAGLNFRDVVVALGMVADVRSLGGEGAGVVIEVAPDVSHLAVGD
RVMGLLSGTGPVTMTDARLVTRMPDGWSFAEAATLPIVYLTAYYGLSDLAGVQRGERLLL
HAATGGVGLATLELAEHWGLEVFTTASPAKQYVLRDRGIPDTHVASSRTLDFEQHFRATA
GAPGVDIVLNSLAGDFTDASLRLLGDGGRFIEIGKTDIRDADTVSAEHDHDVVYQAFDLG
DAGPDRIQEMLQELRELFVSGALKPLPVTAWDIHDAQQAIRFLSQARHIGKVVLTLPSGI
SPEGTVLITGGTGVLGGHIARELVAGHGARHLLLASRSGADAAGAAELRAELEALGAEVR
VESCDAADRDQLAELLDTVPAEHPLSAVVHAAGVLDDATVERLTPEQLAFVRRPKVDAAW
NLHELTAGSDLDAFVLFSSAAAGLGAPGQANYASANAFLDALAVHRRHQGLPAGSLGWGY
WAEASGMTGHMSDADTERLVRGGVRPLRTETALRLFSTALTSGAPSLLPIDLDTKRLSPE
SAPALLRGLVRRPTRRVAAGAGAGAVAGLAGSLAGLSPAAQREQLLALVSQHVAAVLGHA
AGVDADRAFKELGVDSLTAVELRNRLGAATGVQLPTTVVFDHPSPKALTQYLLTQLVGTE
SAGTARPATSNGTSQDDEPIVIVGMACRFPGDVSSPEDLWRLLADGGSGIGEFPTDRGWD
IERLLDPDPDHAGTSTTRRGGFLHSAAQFDAELFRISPREALATDPQQRLLLETAWETFE
SAGIDPTSLKGSATGVFAGLTSQDYFSRLSSIPEDLEGYLGSGSLASIASGRIAYTLGLE
GPAVTVDTACSSSLVALHMAAQSLRNGECDLALAGGVTIMSTPNAFVVFSRQRGLAPDGR
CKPFAAGADGTGWSEGVGLLLVERLSDAVRNGHQVLAVVKGSAMNQDGASNGLTAPNGPS
QERVILQALANSGLSAADVQAVEAHGTGTTLGDPIEAQAILATYGQDRPEDAPLWLGSLK
SNIGHTQAAAGVGGVIKMVMAMREGVLPQTLHVDEPTPHVDWSAGAVELLRENTPWTVGE
DRPRRAGVSSFGMSGTNAHVILEQAPAAEPVETTETDDPAGSSSGVVVWPVSGHTSDALG
AQASRLHAYLAAHPEVTAEQVAHALTTTRAALTHRGAVVATEYAELMEGLAALGEGAPSA
HVVSGVTRPQGKTVFVFPGQGAQWPLMTADLLTTEPVYAQSIDACAKALAPYVDWSLRDV
LTDPAGELLERVDVVQPALFAVMVSLARLWEHHGTSADAVIGHSQGEIAAAHIAGALSLE
DAAKIVALRSKALTTLTGRGTMASVTLPHEQVTEQIAGYDSLSVAVINSPTHTVISGTTE
DIHTYLDHCQTNNIQTRLLPVDYASHSPHVEALEEHLLTVLADITPQAASIPFHSTTHPI
DRPTDTTTLNSTYWYDNLRQPVHFHTTLTHLNNTSHTTYIETSPHPTLTTPINQTNENPE
TDNGNDTPLTVTGTLRRHQXGPTQFRLAQATLHTHNTPTTWPTPTTQPTTLPTYAFQHQH
YWLNDTPTQANLTTAGLTPANHPLLAATIQHPDNHTTTFTGTLSLRTHPWLADHTVTGTI
LLPGTAYIDLALHAGHHTNHPHLTELTLQTPLTIPENETVQLHIATGPEDPATQDLIPVT
IHSRQADDEPWTLHATGLLADAGATNYPAEPASWPPADATALSTDSLYDDLATHGYGYGP
AFQGLTAAWRDGDNLYAEIELDPDTDVTGYGIHPALLDAALHTLALGSSDEQRVQLPFSW
SGVELFSTGATSVRARITQTDASSVSLVLTDPQGALVARIQALTMRAIDTAQLAAAGTST
HNRLFAVEWTATALASDGGTDAGDHQAWTILTAGTPATAPPESITHLELDPADPDLPLPQ
QVHHAAAQTLQHLQDWLTDPANTDRHLIVLTHHAVTTHPGENITDLTHAPLWGLIRSAQN
EHPHRITLIDTDNHPDSNKHLPGAVHAATTAGEPKLALRNGDTLVPRLARHTPTPGNTLT
PNPHGTTLITGGTGTLGTHIARHLVTHHSARHLLLTSRTGPETERAQALLKELTALGADV
RIAACDAADRQQLTALLDTIPAEHPLTAVIHTAGVLDDATIDNLTPQQLTTVLAPKVDAA
WNLHQLTADHNLDAFILFSSAAATLGATGQANYATANTFLDALAHHRHHNGQPTTSLAWG
YWAQPTGMTAHMDDGHVAKLRRSGLVPMTSETGMALFDIAAAPGEPPMLLPAELSPSHID
ADSVPPLMRGLVRPVRRAAAGSTPGGPTGLLGRLSGLEVHEAREELVKLVSAHVSAVLGH
GPGASASPDKAFKDLGFDSLTAVELRNRLAATTGLRLPATLVFDHPSPKAVALHLHEELF
AGGPASGEAVAVTVPKNPLAELDRLDAALLAGTDDSVLDRVALRLTAVLARLNADRNERE
AAAREDTTSDRLQGASSDELFDFIDKDLGRNSHA
>B1KJP2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Shewanella woodyi (strain ATCC 51908 / MS32)|TrEMBL
MSQTSKPSKPLADKKSAKASSTNTAEMNQDPQADKRLNKRLKDMPIAIVGMASIFANSRY
LNKFWDLISEKIDAITELPSTHWQPEEYYDANKSTPDKSYCKRGGFLPDVDFNPMEFGLP
PNILELTDSSQLLSLIVAKEVLADANLPEGYDRDKIGITLGVGGGQKISHSLTARLQYPV
LKKVFANSGISDEDSAMLIKKFQDQYVHWEENSFPGSLGNVISGRIANRFDLGGMNCVVD
AACAGSLAAMRMALTELTEGRSEMMITGGVCTDNSPSMYMSFSKTPAFTTNETIQPFDID
SKGMMIGEGIGMIALKRLEDAERDGDRIYSVIKGIGSSSDGKFKSIYAPRPEGQAKALNR
AYDDAGFAPHTLGLIEAHGTGTAAGDAAEFAGLCSVFANGNDTKQHIALGSVKSQIGHTK
STAGTAGLIKAALALHHKVLPATINVSQPSPKLDIENSPFYLNTETRPWLPRVDGTPRRA
GISSFGFGGTNFHFVLEEYNNEHSRLDSEKAKYRQRQVAQSFLISASSKDALIAELNKLA
TAATTDEFIIATAAQDYGLRELDANAPRIGLVANTAEELATQIKQAIAKLATDTLAAQEG
FQLPGGTSYRANAVTGKVAALFAGQGSQYLNMGRDLACYYPEMRQQFVAADKVFAANDKT
PLSQTLYPKPVFNKDDLKAQEAILTNTANAQSAIGAISMGQYELFTAAGFNADMVAGHSF
GELSALCASGAISTDDYYKLAFARGDAMATKAPAKNGVEADAGAMFAIITKSAADLESVE
ATIAKFDGVKVANYNAPTQSVIAGPTSSTGEAAKALSELGYKAINLPVSGAFHTELVGHA
QAPFAKAIDGAKFSKPTRALYSNATGELYANTGAKIKASFKKHMLQSVRFTAELEAMYKD
GARIFVEFGPKNILQKLVQGTLADRMNELCAISINPSPKGDSDLQLKQAAVQLAVAGIKL
DNIDPYQADIAAPEKRSPMSISLNAVNHISKSTRAKMEKSLHTGAVTSSTIVEEKVVEKV
VEVEKIVEVEKIVEVPTVVEKIVEVSTAQANPVITHSVQESQVVSQNKPAFNTEPSAVLN
VSSDALTSFFAAQQQAAELHQQFLEIPQQYGETFTTLMTEQTKLAGSGVAIPESLQRSME
QFHQLQAQTLQSHTQFLEMQAGSNIAALNLLNGTPAPVQVAPIAQPAVIQAAPSTVAPIV
SAPVQAAPAKVATPAPMAAPVVQVAPAITPVQAVTVAQAAKVESRVEPVATSNTSAADSP
PLKAAEGSLSAQKVQATMLEVVAEKTGYPTEMLELEMDMEADLGIDSIKRVEILGTVQDE
LPDLPELSPEDLAECRTLGEIVSYMNSKLPSVGSQATATSTTDSSTLKAAEGSLSTGLSA
EKVQSTMMSVVAEKTGYPTEMLELEMDMEADLGIDSIKRVEILGTVQDELPGLPELSPED
LAECRTLGEIVSYMNSKLPSVGSATSTTDSSPLKAAEGSLSTGLSADQVQGTMMSVVAEK
TGYPTEMLELEMDMEADLGIDSIKRVEILGTVQDELPGLPELNPEDLAECRTLGEIVTYM
NSKLPSVGTNTSAAAAPATSGLSAETTLSAETVQSTMMSVVAEKTGYPTEMLELSMDMEA
DLGIDSIKRVEILGTVQDELPDLPELNPEDLAECRTLGEIVTYMNSKLPSVGANTSAAAA
PATSGLSAETALSAALSAEKVQATMMSVVADKTGYPTEMLELSMDMEADLGIDSIKRVEI
LGTVQDELPGLPELNPEDLAECRTLGEIVSYMNSKLPSVGSQATATSTTDSSPLKAAEGS
LSTALSADQVQGTMMSVVAEKTGYPTEMLELSMDMEADLGIDSIKRVEILGTVQDELPGL
PELNPEDLAECRTLGEIVSYMNSKLSTTDAEGSRSTVGAAVSGAVKSVAETITSSLELPP
HSEVALKKLKAADQINNCFAADATVVINDDGHNAGVLAEKLTKQGLKVAVVRLPKGAAQS
PLNSDVASFQATSLDETGISAIIAQIEQQLGQIGGFIHLQPEADSNSVNNAVNLSDDSYT
HVSQAFLWAKLLQPKLTTSSDKRRSFITVSRIDGGFGYLDARALENAELNQAALAGLTKT
LSHEWPSVFCRALDIATSLDATHLADAITAELFDSVTGLPEVGLSIDNKGNVSRCTLVAG
EASNKTAKAELNSIDKILVTGGAKGVTFECALALAKRTQSHFILAGRSELQAIPTWATGK
QISELKPAAIAHIISTGSKPTPKQVEALVWTVKSSIEINTALNAFAEVGASAEYVSMDVT
DTAAITKALNGRSSEITGLIHGAGVLADKHIQDKTIEELARVYGTKVNGLKALLAALDSS
KVKLLAMFSSAAGFYGNTGQSDYAMSNDILNKAALQFTARNPQAKVMSFNWGPWDGGMVT
DALKKMFTERGVYVIPLKAGAELFATQLLSETGAQLLIGTSMQGGDDASKKDASVKKLNA
GEVFYASHPLAPVSLTRALNPNDMVFIQDHRISGNPVLPTVCAIQWMREAASKVLGAQVK
VLDYKLLKGIIFDSSNAQEITLELTPTDNNQIAALISSQGRPQYKATLAVSNETFATKSI
DLTGEAITDSAELYSNGTLFHGPRLQGIKQVFNFDDAGLLASCQLPQVDDSDCGQFVATQ
HIGGSQPFAEDLLLQAMLVWARIKYGAASLPSTIGEFVSNKPLAFGDKAVLTLEVVKTSA
RSLEANVALYHENGELSAMMKGAKVTISKNLNSAFLNENSTANRISGEKS
>A0A1V2RTB3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MSVSEAWVHGVAVEWARVFEGARRVDVPTYPFQRRRYWLDAPPPGRRGTGTDDWLYRVAW
RPASEPAQPPALAGTWLLLTPSGAVENDAMAAVADGLKGAGADVVVAAAGEAGPPGSQVA
GVVSLLALADAGDPLPATAALPGALARAGIAAPLWVLTRQAVTTGTADAPPDPWQARLWG
LGRVAALEHPERWGGLVDLPGQADQAAVARLAAVLAGAAGQEDQLAVHATGLAVRRLTRA
PAAAAAGTWHPGEGTVLVTGGTGALGAHVARWLARRGAAHLLLLSRRGDGAPGAAVLAEE
LRGLGAGVTVAACDAGDRDALARTLADVPEDRPLTAVFHTAGVLDDGALDDLTPERFAAV
ARPKSDAALHLHELTAGLDLSAFVLFSSFAGAVGNVGQANYAAANAFLDALAERRRAEGL
PATSLAWGAWAEAGLATGEVGERLRQRGVAPMDPQRAVAAMHTALDGDETAVGVAAIEWG
TFAQALRAVRPAPLLDELPEAAPAADDGAPGQGLAERLAGHDAEERQEIVSGLVRGHVAA
VLRHAAPDSVDGGRAFRDLGFDSLTAVDLRNRLGAATGLRLPTTLAFDHPTIDDLTAHLL
AELAPADTGPAEGAAELRRLLDRIPFTRLKESGLYEALRNLAEEPAPERPAEPAGTAQER
ELEDEEIDGMSVADLVQLVLSDDGDSSNGSNHTSGTDDTDDTAYGKTGDQQ
>A0A1V2RP37|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MSRSDSVPTERLHAGKDAIAVVGVSCRLPSADDPAGFWRLLTGGRSAVSQVPPGRWDEGA
AVSDETVLGAFLDHVDRFDAEFFGISPREARAMDPQQRLALELGWEVLEDAGVLPDAVRG
SDTGVFVGVTADDYGALDRRRGPAAIGHHTLTGLNRSVIANRMSYSLGLRGPSLVVDTGQ
SSSLVAVHLACESLRRGESATALAGGVHLNLLPDSAEAVARLGALSPDGRCFTFDERANG
YVRGEGAGMVLLKPLARALADGDDVHCVIEGSAVNNDGPGEGLTIPDARGQQAVLRAACR
RAGVDPAAVQYVELHGTGTRVGDPVEAAALGAVYGAGRSSDSPLLVGSAKTNVGHLEGAA
GIVGLVKVALSLRNGALPPSLGFERPNPLIRFDEWRVDVVTSARPWPYREGRALAGVSSF
GIGGTNCHLIVSAAERKPRTPQTPQTPGNAAPAADRASAAGGPVPWPLSGRTHDALRAQA
ARLASQLAENPRLDPVDVGFSLAGSRTSTFRHRAVVLPSGGPGGAPGALTALADGESAPG
LVRGVADVEGRTVFVFPGQGSQWTGMGVRLMAESEVFAERLAECAAALAPHVDWSLPEVL
RQAAGAPSLERVDVVQPASWAVMVSLAALWQAHGVVPDAVLGHSQGEIAAACVAGALSLE
DAARVVALRGRTIAAHLSGAGGMLSVPLPRAEVEAWLSPWNGRLSVAALNGPASVAVSGD
LAALEALSGELAGAGVRARRIAIDYASHSAQAERVREELPATLAGIRPRRAEVPLFSTVT
GTWLDTTGMDGEYWYRNLRQTVGFEPAVRALLGQDHRVFVEVSSHPVLTAAVQEVIDAEG
GRAVAVGTLRRDRGGKERFLTCLAEVFVRGVPVDWSRAFAGTGARRVPLPTYAFQRERYW
LAEPAGGAAPLVTGHAQEPEPEPEPEGPGTEPGVPRTRADLGRLVRAETAVVLGSASAER
VNPALSFKELGFDSAMTVELVTRLKNVTGLPVANTALFDHPTPDRFADHLAAGFTGPAAG
GVPAAPRTVPADDPVVVVGMACRYPGGVTSPEELWDLVAGETDAVSGMPTDRGWAPELLA
TGRPGGFLYDADRFDAALFGISPREAEAMDPQQRLALEVSWEAVERAGIAPSSLHGSRTG
VFVGAMAQDYGPRLQDSSGAAEGYVLTGTSPSVLSGRVAYALGLRGPALTVDTACSSSLV
ALHLAAQALRGGECSLALAGGVTVMSEPGIFVEFARQGGLSPDGRCKAYAESADGTGWSE
GVGVLVLERLSDAVRAGHRVLAVLRGSAVNSDGASNGLTAPSGTSQQQVIGQALAGAGLL
PSDVDAVEGHGTGTRLGDPIEAQALLATYGQGRAQDRPLLLGSLKSNIGHTQAAAGVAGV
IKMVLAMRHGVVPRTLHVDAPSAQVDWSAGAVELLTASTPWPRAARPRRAGVSSFGISGT
NAHVIVEQPPEDRAVPPVGPPAAAGPHVVPWPVSARTEAALQAQLGRLAAFVTATGAAAQ
DIGYSLATTRSDLECRAVLLAAADGAGQPVRVAEGTAVGDPGLSAWLFAGQGAQRPGMGR
ELHAAFPVFAAAWDEVCTLLDGELERPLREVVFGDETGLLSRTEYAQPALFALEVALFRL
VESWGAAPDLLLGHSVGEIAAAHVAGVLSLPDACTLVAARGRLMQALPEGGAMIALEAAE
NEVVPLLAGAEDRVGLAAVNGPRAVVVSGDADAVRAIADRFAAEGRRTTRLRVGHPFHSP
LMTPMLDGFRAVVEGLAFAEPRIPIVSTVTGERLQDEQIRTPDYWVRHVGQTVRFADAVG
AAAAAGARVFLELGPDATLSVLAQDVLAQDVPAEVAGAETVPLLGKDQGEETTALTAVAR
LYVRGVPVRWAGLFAGTGARRVELPVYAFQRDRYWTSAAGRGPSAGVVSAGLDRLEHPLL
GAAVERPETGGLLCTGLLSVTAQPWLADHVENGQAVFPATGFLELAVRAGDEAGCGLLEE
LTLAAPLVLPARGRGEVRVQAAIGGPGDDGRRTLNVYARPADPPDTPWTLHATGTLARGT
AAVGTADGQAWPPANAVPVDLEGFHEPAPPGLRAAWEAGDEVLAEIVLPEHVADDADAFR
LHPALLAAALHLVPPAGLDDAEDRWLPFAWAGVSLHAAGASVLRVRMSRTGDDTVTLSAA
DAAGDPVLSVRSLRLRPRDVPAAATAATTFTQPLLRLDWLPAPVPDAGGHDRVADGADGA
DGAAVLVPVTVPAGLPVPEAVRDVTASVLDVLRQRLDDEDDGGPLPQLVFVTRGAVATTS
GETPDVVAAAVWGLVRSAREESPGRFVLLDVDPADDGDPGTVLRAALDCGEPELALRAGK
LLVPRLAPAAGPRPAAPGTVWDGDGTVLITGGLGGLGALVARHLVTVHGVRHLVLAGRRG
ARAEGAAELVAELTGHGARVVAAACDVSDRAAVAALLAAIPAEHPLTGVVHAAGVLDDGL
VGTLTPDRLDTVFRPKLDGAWHLHELTRDRGPTAFVMFSSVFGVLGNAGQAGYSAANAFL
DALAQRRAADGLPGLSVGWGPWPRDAGMSAGLSAAQVHRIAAAGLPVLSTEQGLAWFDAA
GAAGEASVVAARVDRAALRARDTVPAVFRGLVPAARRAASATGTGFDLPAGPATDLLRLV
REQAAAVLGHRGPVVGAEGRTFKDMGFDSLTTGQLRHSLRKRTGLNLPSTLVYDHPTPEA
LAAHLRAELGGGADERPTPAPAPAPAGGAVARGSDAEPIAIIGMSCRFPGGVRSPRQLWE
LLIAGTDAVSPLPADRGWDPGLYHPDPGRTGTTYSAAGGFLDGADEFDAGFFGISPREAT
SMDPQQRILLELAWEAFERAGLDPTSLRGSTTGTFVSATAQQHGAGASTDSDGYQLTGTI
PSVLSGRIAYLFDFQGPTVTVDTACSASLVALHMACQSLRAGESTLALAGGATVLTGPDT
LVSLSRHRVTAPDGRCKAFAESADGMGIAEGAGLLVLERLSDAVRNGHRVLALVRGSAMN
SDGASNGLTAPSGPAQQRVIRQALANSGLAASDVDAVEAHGTGTALGDPIEAHALLATYG
QDRGDSPPLLVGSVKSNIGHTQVAAGVAGVIKMVMALRHGRLPKTLHVATPSSRIDWDAG
AVGLLTEPAPWPELGRPRRCGVSAFGMSGTNAHVVLEQAPAHAPAPVSAQAPAQAPAPAA
EGPVAWPLAGKSAGALRGQAAELLAHLDSHLDDRPVLRPVDIGYSLATTRTAFEHRAVLV
GDDQATLRGGLAALAEGTSHPGVLRGTAPGRGPVVFVFPGQDAAWRGMAAELLDASPVFA
ARIGECEAALAPYLDWSPTDVMRGELGAPPVEGRPDVLQPVLWSVMVSLAALWRSFGVEP
AAVVGHSQGEIAAACVSGGLSLDDGARVVALRSRLIRERLSGSGAMMSVMASQEQVRPLM
DGVSGAVSIAVVNGPRTVTLSGDPAALREVERGLSKAGIMRWWLEGVDFAAHSAHTDRIE
AELLDVLAPVRPGPSEVPFWSTVTGGRLDTEELDARYWCRNLRETVSFAETMTGLVHEGH
GFMIEISPHPVLSIGISDIVESADSPALALGTLRRDDGGWDRVLRSLGEAYAHGAPVDWS
AVLAGGRTVDLPTYAFQHESYWTAPTAPTVAAPGPVGQAGAPGSADEPLWDAVGRGDPAA
VAALIGLEGEEDRAALGSVLPALSAWRGRQDRHTRTSTRRYRTVWTPLRVPADPSLTGTW
LVLTTDGADGADVLAALAAHGAEARRVVVDGTCTDPGKLAERLGDVHRAAGVLSLLAAAE
ETDCGGTALPTGLALTVSLIRALMESGAEVPLWMVTRGAVSTGAADPVRHPRQAMVLGLG
RTAAVEAPSLRGGLADLPERLDTRTARRFAALLTTGSGENQAAVRSSGVLVRRLVRAPAR
AGSPSTWAPGGTTLVTGGTGALGSRVARWLARQGAGHLVLTSRRGAAAPGTIALAAELSA
QGASVEVVPCDLTDRKDVATVLDRLAADGRPVRAVMHTAGTRVLGPIGTSGPAHFADAAH
AKVAGAAHLDELLDDSGLDAFVMFSSMAGVWGIGHHAAQAVADAYLGALAAQRRARGACA
TALSCSPWQEARGQMSEQDGEQLLRSGMSFLDGELALAGLAQALHEEETALTIADIDWVR
YLSVATANGPSAFFDELSEAQTAPAAASGDGRFTQRLRAAPPAGRRQLLVDLVRNEAAAV
LGHASAEALDEHAAFPDHGMDSLASVDLRNRLAAVLDTALPSTVVLLHPTPADLAGHLLD
HLASPRAEESGSGGAPAPDLVAELHRDAVRTGRLDEAESLLLGLAALRPRSSGPVPPTVE
RLAAGTGTGASGSHLVCVAPIVPLTGPHTYAALTQALPDDWAVTCLTPPGFRADEELPAT
REALVEGLALAVGAPTQPVVLLGTSSGGILAHETARHLAAHGTPVRAVVLLDTYILESPT
ARGLLPHLWHGLYEREHLTDGYTGAGLSAYAWTERLLRTWTPAPVPFPTLLLRASEPMPL
PPGADPAPNGWQTGLPHITTTRTVAGNHFTLINQHAPATAAHLAEWLAGETRP
>D5UX42|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / CCUG 35730 / CIP 100753 / JCM 10117 / KCTC 9821 / NBRC 16120 / NCIMB 702349 / NCTC 13040)|TrEMBL
MVGGEPGVGVAMVTTEKVAVVGISCTFPGGDSPSSWWSFLETGAEGVADAETLDAFDAWR
LGAPRGGLIDAVTDFDAAFFRISPREARAMDPQQRILLQSSWKLLEDARITDADRRANRI
AVYVGAMSSDYSALAARSGRVTDRHTLTSTARSLLANRLSHALGLGGESLTVDTGQSSSL
AAVHLAASAVARGDTDIALAGGVNLILDPQGTETAGAFGALSPDGRCFTMDERANGYVRG
EGVGLIALKSLSRARADGDRIYCVIDGSAMRSDGADDALTVPARAGQARTFRAAYENAGV
DPATIEYVELHGTGTAVGDPIEAHALGEVLGTPRRAAGRDPLRVGSVKTVIGHLEGAAGI
AGFIRTALAIHHGVLPRSANFVTPNPAAALHENHLAVQVTPEIWAGPGRRAAVSAFGMGG
TNVHVVLSAVPAQAEEAAAGADDGSGGAPSAPDATVVPLLLSGPDDAALARQARTWHDWL
SGRSDRERSDAARISLLRPRLGRTAVIAEPSTAGCTAELAALADSIAGPSTSVLGQATGD
GAGAGSVSWVFSGQGTQRAGAGAGLYSQHPVFAKTVDRITEAFIPLLGVDLRRYLLAEPD
SPLSAELTDTRIAQAAVFTVQSGLAALLGAYGARPDSVTGHSVGEYAAAVVAGVMSEADA
VYLVAHRGLLMSALPSGGGMVSLRADADAVAELLGAGDTPVEIAAVNAADNIVLSGESDA
IAEVIAAAATRGISAKPLRVSHAFHSRAMDPVLAPFREHATAVTLAEPTIPFVSTVSGRA
MTTELADPEYWVQQIRQPVAFHAAVTALAQAGTRGFIEIGPQSSLTAVIGETVPDATAVI
PVLHHSKSEQQTLSTALGVHAVTTGTGRRTYELLRVHGQPLVEPPTYEFDRRRYWAFDAE
TSSAETDPGAAVFVGSPAPDAHARPEPTADHASSDDPDAVPPKTVRAALAAVLGADAGEL
DLTATFTALGLDSMGAVELVQRLQPFTSTRLTPSVVFDHPTPASLIAYLGSTDGAAETST
AAIASTAADDPVVVIAMDCLLPGGADGPAALWRLLIDEVDAIGPFPDDRDWNTEGLFADD
PSVPGTSYAREGGFLEAATSFDPAFFGLSPREATAMDPQQRLLLQLTHRAWERAGLTEAD
LRGSDTGVFVGAMAQPYGPPMDSAAPETEGYLLTGVSPSVLSGRIAYHYGLTGPALTVDT
ACSSSLVAVHLAAQAIRSGACSLALAGGVTVMPTPGMFVELSRQQALSPSARCRAFSADA
DGTGWGEGAGLVLLTRASIARTRGIPVLAVIEGSAINQDGASNGLTAPSGTAQQRVIDEA
TRAAGVDLASVDAVEAHGTGTKLGDPIEANALIATYGQRPDTADPLWLGSLKSNVGHSQA
AAGVVGLIKMVLALGAERLPRTLHVTAPSPFVDWSAGRVELLTEPRPWPVTPGRTRRAGI
SSFGISGTNAHLILAEPTWLEADDTAATALPAPANPGADRLHLLAVTAPDAAALSRRCTD
LADFLEGTATDLGDLAAVLATTRTHWAHRVVVLAADTPTAVAALRAAATGDPFSGCRGIA
APGETTFVFPGQGAQWPGMAAGLIASEPVFEAELRRADAVIAELAGWSVIDVLTGAPGAP
DPERIDVIQPVLFATMVSLGALWRSYGVRPDTVIGHSQGEVAAAYFAGALSLRDAATVIV
VRSRVSRTADGTGGMLSILAPRTEVATLLRESGAALDIAAVNSSRSTTVAGLARDLDTFA
ETVAAAGFDCRRIPGVTMAGHSRVCEPLREDLLAGLQAIRPRPASVEMLSTVTAAEVDGA
ALDADYWYRNLRETVDFHGASLARLAQGRSVFIEVSTHPLLVNALSTTIEESSAAGAGVG
TLSRGAGDRATFLLALAQAFVSGVPADLRTRDGDGDPLGFRDRGLPARLPAYPFARTRLW
LPATPAGAVDAAALGGSDVAGPLVTARLHTPGAGGEVFTGRIAVDDPAAAVGLLVELALE
AGDEAGYALLARLDVTGPLPPARECIAQVHLAEVGGERTAFTIHVRSTGGEDDWVQVAEG
ELRDSPAVATVPDPLPASATVDPELVTGTVHTGGAGPDESPVSIAAVRRGPEALDVDLDL
PDDSDHPDSAAAILAPALLGAAGTLAGHLLDPDGAAAPLAVLRVEGLGSLLQGVRAVRIA
LRMRGGTESGAVVDMTITDRTGAPVTPTATLTLGTPRTMAASAIEARRTMYVVDWRDAAP
HDVAVGTGQERGPEPYLVPDGTDATAPQRAREVTETVLERLREHLAADDPEAVLAIHTRH
AVVTGLEHEEANPVHAAVWGLVRSAQTETPGRFVLIDSDGHPDSAAAVSAAGRAGHPQVA
VRAGRLCLPRLRRYSEHPSDSPRPANNGTVLVTGATGGLGRMVAEHLVREHGVRDLVLVS
RGGPRSSGADELIANLIDLGARPELVACDAADRDAIAEVIAGITAHRPPLRAVIHTAGVL
DDATIANLTREKIDAVFRAKVDALEHLDELTADLDLDYFLVYSSMVASFGNPGQANYAAA
NAYMESLISRRRRRGLAGTAIGWGYWATDSAMSAHLSELDISRIRRTGVIPLGADQGMAV
VDTLLAAPGQDAPPAVLAVPFDPTVITSRATDPELSPLIRSLAPPSRRRAVATRTTTGTA
LQRLLARALPAEWRRLTAELVRTQVRTVLGTAPDSPLDGGRALRDIGFDSLTSVELRNRL
AAETGLALPTTLVFDHPTPDHLTDYLLRQVAEDEEAPDGVDDAAPDRPDASPRSLDDDPI
VIVSMACRLPGGVRSADDLWNLVAHGRHGIGPFPEDRGWPAELYHADPAAKGHSYTRHGG
FIYDAAEFDAGFFGMSPREALATDPQHRLMLETVWEALEEAAIDPHSLRGANVGVYIGSV
GQDYVHLGDRVDESLEGFLVTGRASSVLSGRVSYTFGFEGPAITVDTACSSSLVALHLAV
TALRRDECEMAVVGGVSIMADPGLFIEFSRQRGLAADGHCKTFSEQADGTAWAEGIGVLL
VERRSHALRYGHRILAEVSGTAINQDGASNGLTAPSGPAQRRVIAAALADAGVAPSEIDL
VEAHGTGTPLGDPIEAGALIEAYGEHRDGAAPLYVGALKTNTGHTQGAAGIAGVIKTVLA
LRHQLMPRSLWGRNRSSAVTWQGVELLPDERPWPHGERRRRAGVSAFGISGTNAHVIVSE
PVVPSDTPHRAPEGVAPEELGLTVWPVSADDPDALSVLLESVPHALEHTADPADAGAALT
TGRAQLTHRAVLLPGEPEPIARGAVTDAGTVFVFSGQGGQWLDMGRALAEASPTFASALD
DVCAAVDRYLDRPIRDIMWHSDSGDSGTDALLNDTRYSQPAIFAIQVALLRLVEALGLRP
DAVIGHSVGEVAAAHAAGILGLDAAARFIAARGTQMSAAPAGGAMAAIAAPPDRVHGLIT
RDASPHHGTDPVVIAAINGPAAVTVSGSAAAVAAAVDAATAAGIRTKTLQVSHAFHSAQM
AAAAHGLAGVADEIDFQKPRIPFLPTGGRSRAVHNPAYWTEQVTAPVDFLGAVNEAAERG
PARYLVLGPDSALVAALREATNGSVATALMSPKTGTTAQGAARDAATALGRLWADGAPVT
WAALYRDRDPHAVRMPSYPFQRKHYWIIPDRRSASAPPTGLCYESSWIPIPAAAGGAPVD
RVVLAVAADTHTDVVDTVRKALLEAGHEPIVATVDEIERSTIVSGATTVLALLSFTDSER
APEDTLRLAQLAERSGAALVVVTGADGGAHTAVAALARTIGLEAPHTISTIVQIASPTDL
AQAGRLAGIIGGSPEREIAVSTESGIAGRRLVRVDSADTAPFRPSGTVLITGGTGGLGSE
IARWCARNGAERVVLASRGGERSPGAASLVAELDELGTDCTVLTADCGDRPAFRSALSAF
EGASGGEITAVFHAAGIVDFTSFTATEPADVRRLAAGKVTGARVLDEYFHDRELDAFVLF
SSIAATWGSAGQSAYSAANGYLDGLAAQRRARGLAAISVAWGPWAEVGMITTDGVADALD
KHGLIAMPAAAAIAALADTLGNPTVGAAVVIADVDWRRFLRTYSATGDTCLFELVANDHD
GESARPDDRSDHPRRTPQTLLDRLAQSPVEARDAAVREVTDRLVAEVLGAATHSRIDGTR
AFRDLGFDSLMTVELRDRLIAETGLAVSAMTIFDNPSPHELHRHLLGLVSAALDPDPLSQ
LDQLETGLSALAEDDARRTELAARLRDLADRFAEPRAAADEPAPAELADADADAVIAFLD
GLES
>A0A7Z6T598|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. CBMAI 2042|TrEMBL
MADLTPARTHGRHEPVAIVGIGCRLPARIEDPAALWQALLDGVDAVRQVPADRWNAPAWA
DAEASGGAANRRGGFLDDVTGFDAEHFSIPPAEARQMDPQQRIALEVACAAVEDARRSTA
SLAGTRTGVFMGAMWQEYPLFTQGATEAIHAHSAIGWDTSVIPSRIAYALGLRGPAMGVA
TASSSSLVAVHLAVQSLRSGESDLALAGGVNLMLHPNTSVALTKLGTQSPAGLSRAFDGD
GDGYARGEGCAVVVLRRLSDALADGDRVYALVHGSAVNNDGATDGLTAPGRQAQTEVLRS
AWENAGVAPRAVSYVEAHGTGTPLGDVTEAGALGTVFGPDRPAPLRIGSAKTNFGHLESA
AGVLGLVKAALAVHHGVIPPSLHFRTPNPRIDFAAERLEVVTETTAWPAGPRFAGVSSFG
YGGTNAHVALGEAPESAPVRATTPDAGGPVCLAVSGTGPQALARNAARLADHLGRSSGTR
LSDVAHSLATTRTHHRTRGMVIAGTTDEAVAGLRALAADESHDAVVTGAAAERGRVAFVF
PGQGAQWWGMGASLWEQNEAFREAVTACDEALAPHTGFSVADVVRGQDGIAPSFTRTDVV
QPALFAMYVGLAAMWRAWGVEPGAVVGHSQGEVAAAVVSGALSLADGARIVALRARAVRD
HAPDGAMGLVERPVGEVTEELAAYGEALSVAVVNTARSTVVAGDAEVLDRFLGRMEATGA
YCQRVDVDYASHSPHMDALLPELREQLAGLAPEDTEIAFYSSVTGERAAGPELDGVYWCR
NLREPVRFDRALERLRADGFGTFVEVSPHPVLQIALAQGTEADGAAVVVGSLRRDRGGLE
QPLRALAELHVQGVSIPWKRVFPASDGHGVDLPTYAFEHRRYWLDEHDDAMPAAGSASWR
EAVMALPEPERPGSLVALVTEEAAALLGRPVEAIRPDLTLREQGFDSLMVVELRNRLSAR
TRVPLPTVLAFDYPTPQAIATLLLTHADTQDPGDRAADVPPAVAAESERPDEDDPVVIVS
MACRLPDGIETPEAFWDLLADGREASSPFPQRWDGWDLGTIEEAERAATGRRFERKGGFV
RDVEDFDAAFFGLSPREALSLDPQQRLVLEVVWEAIERANLRAASLEGSNTGVYIGSMSS
DYDVAGRWDVGSSDGYKITGNGSSLISGRVSYTLGLSGPALTIDTACSSSLVALRLACEA
LRNGECDLALAGGVTVMSTPQIFVEFSRLNGLAADGRCKSFADDADGTSWAEGCGVLVLK
RLSDARRDGDRVLAVVRGTAMNQDGRSQGLTAPNGLAQQRVVRSALADGGLTPADIDAVE
AHATGTVLGDPIEAGALAAVFSGRVRPLHLGSAKSNIGHAQAASGVIGVIKMVLALQHEL
LPRTLHAEKPNTRIDWTGGELELLRRPRKWPRTRRVRRAGISSFGISGTNTHVIIEEAPE
AVGADRTGDDLVHPLVISGTDVTALRAQARHWAEWLDARPAATMRDIAYTSAVGRTHLEA
RAVVFAGSASEGAEALRAVEYGPGTALGEIAFVFGGQGGQPPGVNRQLLEQSAVFRDTVA
ECDAALSPLTGWSVLKVLRGEEDVSGPDVRPGTLFATYLGRAALWRSWGVEPAAVVVGDA
HGEVAAAVVSGALTMEDGARVIALRARARSGDAVGDAMAGIVPGRASLPVHSGLTGEVVL
GPELGGDPWLGDLHDQEQEPWLESDSSRLDLVLERLRGEGFGAFVDVGPPADGGPGGVDQ
LWRAAAALFERGFPLDWERVLGSHGAGKADVPTYAFQRRRFWLGEPPSGPAKVTLGRPAS
DHPWFDSATTLAGSGGHLFTGRLSLDESPWLADHVVGGQVYVPGAGLIDAALFAAHTAGA
DAVADLTLLEPVVLLPGRVLRIQATVGDPDAHGRRPFALHSQPEDTAEPLTWQQHVTGEC
VTRASADATVPSDLGSGPMPDARALDIEAFYARALANGLDYSPAFRGLRELVCRDGVYHA
RVSLPSALDEAGHGLHPALLDAALQVVVAGLMEAGAAPGPLVPFIWSDVELFRTAGRELT
VRVSFASGGGEDLAPATVWLADPAGHPVARIGGLKFQPGRRRGHPFAEHLYRVGFEAVHP
EAEAVDPAGTLVVGDAEVGAGLGADVVTDLDTLVKRLDGPADTPRRLLFALSDSVSAQRY
DAEGGAAEALRTLQVCLGDPRLQGAELLWITRDAVASSPDDPVENWAHAAVWGMVRTART
EQPERVLRLIDLDPGTPDFRLLARVIETSGEPECVLRGGTVRVPRARPTVEEVDALVLPD
QGGWHLNRREDGQLDLIAAPHDEGAPEPVAPGEVRVEVRAAGLSPAEAQVLEFAGTVREV
GSGVTSIHAGDRVMGRAPGVLGKEIRVDGATLRPIPAHLTFAQAAAHPSASDPGRDQESF
TAFDVRDAPYALRHPQRNAPHKAVLTLPRALDQDGTVLITGGLGELGSALAAHLVRAHGV
RRLVLLSRRGGNAPEAGPFVRELEAEGAERVDLVAGDAADRAAVAAVLEGIDPGHPLTAV
FHLAGVLDDGLVEGFTPERLHRVMAPKVQGARLLDELTERLDLAAFVLFSSAAGTLGTAG
QSGYAAANATLDALAANRRKRGLAGLSLAFGLWEQAGVGMTAHLGKAELGRLRRQGIGAL
TLAEGLNALDVALARPETQLMPVRLELASLRHALGDAEAPPLLRAMLRPTAEGLGAEVPG
TTQSLDTRMADATEAERPALLLDLVRSEVADVLGLPGPDSVPADRALRSLGIDSLTMVQL
RKRLAKRLNTTLPATLVFDYPTADAIAGLLLHDATTPTRNEK
>A0A3E2MPF9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium marinum|TrEMBL
MGAQLYRQHPVFTTAIDACDAELRPYTGWSVRDVXCXDPDAPSLELVEVIQPVLFAVMIA
LAETLRXYGIVPDAVIGHSQGEIAAAYIAGALXLAEAAKVVALRSAALAQLAGTAPEIAA
AYIAGALXLAEAAKVVALRSAALAQLAGTGTMASVLLSPEELRPLLQPWNTQISIAAING
PAHTIISGDTTAVDQFIGTCEDGGVQIRPIAVDYASHSAHVERLREHLLHELADLNPQPA
RIPLYSTVASELSEHPLDTTAMDADYWYRNLREPVEFYSCVAQLLAHSERVFVELSPHPV
LASALTDALADXGQLTQSAVVTTLRRDRPDMDMVANAIANLHVHGHSPSWQKIYPGATTR
NRELARPRPQPVMAKDLPRRYHXGITHLPIPAPPLLVGGAHSXPCHCQ
>A0A518DIC2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pirellulimonas nuda|TrEMBL
MSDQLSTTELSPETLAGIAAALKDARSRLRQARDAQHEPLAVVGIGCRFPGAADLDAYWR
LLSEGRSGLSDVPADRWGHAELAATAAKQPGKIASSRGGFLDGVDQFDAGFFGLSSREAA
SLDPQHRVFFETAWTALEDAGLETSRLRGSRTGVFLGICSNDYLHLLTQRDASQIDAYLG
TGNAHSTAVGRLSYWLGLVGPSVAIDTACSSSLTAIHYAAQSVRSGESDLAIAGGVNLML
SPELSINLSQAGMLSPRGEIRAFAAGADGFVRGEGCGVVVLKRLSAALADGDRVWAVLRG
TAVGQDGRSNGLTAPSGPSQQAVIRQALAASGLKPADIDYIEAHGTGTELGDPTEMGALG
AVFGERHRPLAVGSVKTNIGHLEGAAGVAGLIKACLALHHGQQPPTLNFAAPSPHIDWSL
PLEVSGELRAWPEEEGRVRRAGVSSFGFGGANAHAVLESAPNKAPGTLLEKVPDTFSWVT
LSARTPAALAEQARRWAGAITPATPVAETAAVAARREAFDCRLAIHADTSEQLVERLGAF
AVGEATAEKRLLVGDAAGTPRAPIGLLFGGQGAVRPRMGKELYERFGVFAETWDRCEAIL
APHWPRSLRTIAWDEPERWLLGVDCQPLLVAWQASLAALWRSWVGPPAWVLGHSLGEFAA
AVAADRIDLEAALPLVCVRARALDAIDPAQRGAMLAVMAPVEHVESLVDGTLAVASLNGP
RQTVVSGSLAEIEALKQRLGRTRSVRLETTHAFHSALVEPALAAVAQAGAGAPTRGSDIG
FFSTLTGAALEGPLPADYWARQLREPVRFHRALMATGASQAIEVSPAAALTPLCPTRPLL
ASGMKPGDEAAGAERAAIELWTAGYDVNRRLVAPRVPIVSRLPGYPFQRRRHWFSPSPAS
KRPAASAAVHPLLGERLDTPAQASVFEVDLATLPWLEDHRVAGRPTLPAAAYLELAIAAG
VQLAPEADWDVSQLSIDARVAWASGESCRVQTHASRAGDQWRLSFYSRGATGEWQACAAA
SLTQRQSRPAPLEGFRTLADADVSQHYAGCRAAGLDYGPAFQGVKSLRGAEGFAEASLCV
TGAEEHECWTPLVDAALQALAAAFPGGTDTAWVPVGVDRFTPCGDLRSPCRARAKLRLSE
HEASATVQILDPAGSLLAEVEGLRLRPLAPPPRDAQRRVDPRSDVLFEMLQVSGDERVER
LTRFLRGRLAGVLDEPEASLSPTAALDSLGLDSLMAYELRDDLQSALGLEAPMELFLQEL
SLRDLAAWLGERLTPDEPAVEASWVEGAL
>A4Y521|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Shewanella putrefaciens (strain CN-32 / ATCC BAA-453)|TrEMBL
MSHTPSVPNSATESKKDKRLNKRLKDMPVAIVGMASIFANSRYLNKFWDLISEKIDAITD
IPDTHWRAEDYYDADKSKADKSYCKRGGFLPEVDFNPMEFGLPPNILELTDTSQLLSLIV
AKEVLADANLPTDYDRDRIGITLGVGGGQKISQSLNSRLQYPVLKKVFKSSGLSDEDSEM
LIKKFQDQYIHWEENSFPGSLGNVIAGRIANRFDFGGMNCVVDAACAGSLAAMRMALTEL
TEGRSDMMLTGGVCTDNSPSMYMSFSKTPAFTTNETIQPFDIDSKGMMIGEGIGMVALKR
LEDAERDGDRIYAVIKGVGASSDGKFKSIYAPRPEGQAKALERAYDDAGFAPHSIGLVEA
HGTGTAAGDVAEFNGLKSVFAQGNDTNQHIALGSVKSQVGHTKSTAGTAGVIKAALALHH
KVLPATINVSKPNPKLNIESSPFYLNTETRPWFQRADATPRRAGVSSFGFGGTNFHLVLE
EYKPEHSRDEQYRQRSVPQTLLFAAANKAALLSELKAALSQSVNTSANANKSSAASLNAI
AQQYPLRPLASTDARLGFVAKDIAQLQAQLNQSIAHLESGHLETSASEVWQLPSGISYRA
KALVTETNSKNDSNKVAALFAGQGSQYLNMGRELACHFPEMRQQVTASDKVFAHHGQTPL
SNILYPIPAFDADAVKAQEAALTNTLFAQSAIGAISMAQYSLLTQAGFAPDMVAGHSFGE
LSALCAAGVISNEDYVELAFARGHAMAQVPSDTASKAVDLGTMFAIILKQKNDIDALNRC
LAQFDGVKIANYNAPTQLVIAGGTEQTQLAAKAISELGFKAIALPVSGAFHTPLVGHAQK
PFAKAIDKAKFSAPSIALYANGTGQLHPSDGKAIKAEFKQHMLQSVRFSEQLQAMYDAGA
RVFVEFGPKNILQKLVENTLGEHLNELCLVSMNPNPKGDSDSQLRLAAVQLAVAGVALTE
VDPYQAVTSQEIAEREAPSAMNIKLTATNHISAATKAKMAKSLATGSVTSQVQYVDRIVE
TVVEKVVEKEVIVEKVVEKIIEVETNQVATVEMKQKSPSVAQGLSNHQQQATAQLSPSTA
SVSGDALTAFFSAQSQAAQLHQQFLAIPQQYGDTFTTLMTEQAKMASLGIAIPESLQRSM
EMFHQHQAQTLQSHTEFMQLQSSSSQAALAMLNNAPINFTPAVASQPRATAPAPASVDPA
PVAATTMPHNAAPVTQAVATEAVSTPVAPVVQTAPVAYSPAVTVQVAPAAPALVMPAVVM
PEVTPAAPATSGLSAGLVQASEIESTMMAVVADKTGYPTEMLELGMDMEADLGIDSIKRV
EILGTVQDELSGLPELSPEDLAECRTLGEIVDYMQSKLTQNDKLPAVGSIIVAPITTANV
ATQVATAAPAVNGLSAALVQQTMMAVVADKTGYPTEMLELSMDMEADLGIDSIKRVEILG
TVQDELPGLPELSPEDLAECRTLGEIVDYMNSKLPAVGSVSAPIATSVTVATNNGLSAAL
VQQTMMAVVADKTGYPTEMLELSMDMEADLGIDSIKRVEILGTVQDELPGLPELSPEDLA
ECRTLGEIVDYMQSKLTQNDKLPAAGSVVVSTTAQAAPAANGLSTALVHASEIESTMMAV
VADKTGYPTEMLELSMDMEADLGIDSIKRVEILGTVQDELPGLPELNPEDLAECRTLGEI
VALFSKEIGQSKLGQNAVSQNAAPVSAVVQPEPTIDLPPHDLPPHSEVVLKKLPAAAELT
QLSPQQSSKQSAQQGLPRVFAKDACIIISDDGHNAGVLAEKLHAQGLTVAVVRSPESLVA
SASPLNSHIASFTLAAIDDASISAVINEIKSLGTVAGFIHLQPQHKTSADAKGLVLSSAA
KASVEQAFLFAKHLQPFLTTAATANTGSSFISVSRIDGGFGYLNHSQIARSELNQAALAG
LTKTLSHEWPNVHCRALDIAPALDAKQLANAVIAELFATDNVLEVGVSQGAAQALERVTL
VAGKANTRHNAANLTSADKILVTGGAKGVTFECALSLAKRSKAHFILAGRSSQQTIPAWA
QGKNNSELKAAAIAHIQSLGEKPTPKQVDALVWSVQSSLEIAAALEAFTAVGASAEYLSL
DVNNPDAIASTIVPITELSPITGIIHGAGVLADKHIQDKTLDELARVYGTKVTGISNLLA
ALDLDKLKLIALFSSAAGFYGNTGQSDYAMSNDILNKAALQLAQQLPNAKVMSFDWGPWD
GGMVNPALKKMFMDRGVYVIPLKAGAELFASQLLSNTGVQLLVGTDMQGSAPHDDTSNKL
QETEGSNLKKPEADLTTDASGPHALASTLAAIAFTRPLTLQRTLDPKAMIFIEDHCINGH
PVLPTVCAIQWMREAAFDVLKQPVKVQSYKLLKGIIFDTAVLQNGVLESEAPITLELELA
PIALTDNAATNTDERLSEQFSALISFEGRPQYQAILVVDDAVDDAASDYLATNSKATAFD
AQSLAGLSVITTASSLYSDGTLFHGPRLQGIESVLKFDDASLIAKVSLPHVALADCGSFV
PNLAPKGSQAFAEDLLLQAMLVWARLKYGAASLPSSIGEFISHAPFAFGDKGYLVLEVVK
HSGRALEANITLYHQDGRLSCEMNNAKVTISKNLNGAFLANKVAANQTAANKAIESVEAK
VE
>A0A655ACI8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MCARIAAVMGYTDQSTVEPAVPLDKPLTELGLDSLMAVRIRNGARADFGVEPPVALILQG
ASLHDLTADLMRQLGLNDPDPALNNADTIRDRARQRAAARHGAAMRRRPKPEVQGG
>A0A0M7BEU2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Lentzea sp. ATCC 31319|TrEMBL
MSAIAVIGMSCRVPGAADPAEFLRNLVAGRSSVTEVPEGRWQGRRGFGGFVDGLDAFDSG
FFGMSRREATWTDPQQRLLLELAWECVEDAAVSTADVKASRWGVFVGACADDFRQRYLAS
GALDRHGHMGTSRSMLANRVSYFFGLRGPSEVVDTGQSSSLVAVHRAVSAIRTGECDAAI
AGGVNLNLLGEVTEQIALWGGLSPDGRCHTFDERANGYVRGEGGGLVVLKPLEAALRDGD
AVHAVIRGSATAHDGGPELLGTPSADAQQDLVEAAHKAAGVSPEDVAYVELHGTGTPAGD
PVEAQALGAAIGRARRVKVGSVKTNVGHLESAAGVTGLLKACLMIRHAVLPPSLNFTRSS
LPLDELNLEVVAQQEDLVLRPHEVIGVSSFGMGGTNAHVVVGPPPVVDQDAWSGNVVWCL
SARSPHALGELARRLNDHDPGDHTPADVAWTLLHRTRWEHRAVVVGSTWDELRQGLASVL
AGNSFAVPLGWEADAGVLRAAGEHLATGDPAAVLALLGAARKVPSLPTHPFDRTEFPVLP
DLPVASTPEPDAEPAFADEWRNAPDRSWRVRSLVERELGDLLGEPLPRGTSGVAFRDLGV
DSQAQMELVDRINTSTGLALADTDIFDCPTIDDLTTHVNTMMEASCA
>A0A2K8QUQ6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MSREEFIQPIHDLLRVNAERLGDKIAYVDSRCELTHAELRTRTGRIAGHLVDLAVERGDR
VAILLGNRVETIESYLAIARAGAIAVPLNPDATGAEVAHFLADSGAVLVITDSAHLDDVR
RAAPAVTVVLVDEGPLPAGTRSFAELATAEPPTPARDDLGLDEAAWMLYTSGTTGTPKGV
VSTQGSGLWSAANCDVPAWELTENDVLLWPAPLFHSLAHHLCLLATTAVGATARIMSGFV
AGEVLHELEEHACTVLVGVPTMYHYLLGAVGEAGPRLPSLKMGLVAGAVSPPALIEGFER
VFGVPLLDTYGCTETTGSLTVNRLSGPRMPGSCGQAVPGISLRFVDPHTGAEVAEGEEGE
LWASGPSLMIGYHGRPDATREVLSDGWYRTGDLARRSETGHITITGRVKELIIRGGENIH
PRDIEAVALELPGVRDAAAAGKQHPVLGEIPALYLVPDVDGVDAEAVLAACREKLSYFKV
PEEIYRVDAIPRTLSGKVKRAALTEAPAELLSAASGNGSLYRLEWVPAETPPAGTGDPVA
VHVTRRAVATGPADLPDQEQAATWDALRREQTGPGGPVLIDLDGADVDDARLSALASLGE
PQIVVRDDTPFVARLAREKSPALTIPGERAWVLEPDHSGVLQELALVAADTDVRPLRPGE
VRIEVRAAGLNFRDVLVALGTDLGDGVFGAEGAGVVLETGSDVPDLRPGDRVFGLLEGGH
GSIAIADRRMLAVIPEGWSFATAASVPEVFVIAYYGLVDLAGLRAGESVLIHAATGGVGM
AATQIARHLGAQVYATAGVGKQHILRDAGLGDDRIADSRTTGFREAFRDSTQGRGVDVVL
NSLKGDFVDASLDLLADGGRFLELGQTDIRDAGEIAAERPGTTYHSFTRMNAGPDRLREI
IAELLALFEQGVLRPSPVHTWDIRHAREAFSWMSGGRHTGKMVLTMPQRIDPGGTVLIAG
GSEALARIAARHLGVRHLLLDRGVADAAPDAVVCDVSDHDALERVLADLSPEHPLTAVIH
TGGAAVTDEIRRLHDLTESLDLTDFVVFSQDAPAAVEAFARSRRAHGLPVRTIAWGIPEA
DPVVADEHLLGRALASAEQAQIVARVNTAGLRALTAANALPPLLRNLIHAEPEETGQSAW
PHRFEAAGADREEALLDLIRANVVDILSLPTADRYAPDRTFREMGIDSLTAVGLRNSLAK
ATGLPLPTTMVFDYPTPAVLTGRMRELLAGESPAPARTAARAVAQDEPLAIVGMACRLPG
GVSSPDDLWRLVAAGTDAISEFPADRGWDVDNLYDPDPDAPGKTYTVLGGFLDGVAGFDA
SFFGISPREALAMDPQQRLMLEVSWEAFEHAGIPPRSVRGSDTGVFMGAFPSGYNAGLEE
FGMTGDAVSVLSGRVSYFFGLEGPAITVDTACSSSLVALHQASSALRQGECSLALVGGVT
VLATPQTFVEFSRQRGLALDGRSKAFADAADGAGWAEGVGVLVVERLSDARAKGHQIWGV
IRGSAVNQDGASNGLSAPNGPSQQRVIRQALANAGLAPHEVDVVEAHGTGTTLGDPIEAQ
AVIATYGQDREQPLLLGSLKSNVGHTQAAAGVSGVIKMVMALQHDTVPATLHVDAPSRHV
DWTAGAVELVTENRPWPETGRVRRAGVSSFGISGTNAHVILESAPEQPVSPPEAVAPVVA
SDRVPLVISAKTPAALAEMENRLRAYLAAAPGADPRAVASTLATARSVFEHRAVLLGENT
ITGTVAGADPRVVFVFPGQGWQQLGMGRALRESSPVFAARMAECAAALSEFVDWDLFTML
DDPAVIDRIDVLQPACWAVMMSLAAVWQAAGVRPDAVIGHSQGEIAAACVAGALSLRDAA
RIVALRSQLLAREMVGHGVMAAVALPADDIPLVDGVWIGARNGPSSTVISGTPEAVEVVV
AACEERGARVRRITAAVASHSPLGEKIRTELLGISASIPSRTPVVPWLSTADGIWIEAPL
DPAYWWRNLREPVGFGPAVDLLQARGENVFLEMSASPVLLPAMNDAVTVATLRRDDGTPD
RMLTALAEAHAHGVIVDWPRVFGSTTRVLDLPTYAFEHQRYWAVSADRPSDAGHPMVETV
VPLPASDGVALTGRVSLATHAWLADHAVRGTALLPGTAFVELVTRAATEVDCPVIDELVI
EAPLVLPQTGAVQLSTTVGEADESGRRPVTVFSQADGTDAWTRHVTATIGRAASLPDPVA
WPPAQAEPVDVTGFYDELAAAGYEYGPAFQGLRAAWRDGDTVYAEVVLAEEQAHEVDRYA
VHPALLDAALQASMVNTAGTGQGVRLPFSWNGIQVHSTGATTLRVAVTPLADGWSVRAAA
DNGRPVATIGSLVTRPVTTDMLGSTTDDLFAVIWTEITAPEPGDPSDVGVFTALPEAGDP
LTQTRALTAQVLQTVQQWLAGEDRPLVVRTGTDLASAAVSGLVRSAQSEHPGRLILVESD
DALTPEQLAGTAGLDEPRIRIDGGHYEVPRLAREDASLTVPEDRAWLLELPGSGTLRDLR
VIATDTAERPLRRGEVRVGVRAGGLNFRDVVVALGMVTDPRPAGGEAAGVVLETGPGVED
LSPGDRVFGILDGGFGSVAIADRRLLAVIPDGWSFTTAASIPVVFATAYYGLVDLAGLRA
GESVLIHAATGGVGMAATQIARHLGAEIYGTAGIAKQHILRDAGLGDDRIADSRTTGFRE
TFRDSTQGRGVDVVLNSLSGDFVDASLDVLADGGRFIEMGKTDIRDAEQITHATYRAFDL
MDAGPDRVREIIAELLGLFEQGVLRPLPVQAWDIRQARDAFTWMSRARHIGKIVLTIPQQ
LDPDGTVLISGGSGVLAGILARHLVAERGVRHLLLVSRSAPSKALISELTALGAQVETAA
CDVSDRAALEQVLDGVPLTAVFHTAAALDDGVVESLTPQRVDTVLRPKADAAWYLHELTR
DADLAAFVMYSSVAGIMGAAGQGNYAAANAFLDALAAHRRREGLPALSLAWGLWEDTSGL
SAGLTETDHDRIRRGGLEAIAAEHGMRLFDTATRQGEPVLLASPLNLTRQGEVPALLRTL
HRPVARRAATANGRPADLTPEALLKLVCGRAAAVLGHVDADAVPVAAAFRDLGVDSLTAV
ELRNSLAKATGLRLPATLVFDYPTPTVLAGRLGELLAGGTAPVRAAVVRRAAASDEPLAI
VGMACRLPGGVLSPEDLWRLVESGGDAISGFPVDRGWDVENLFDPDPDAAGKTYTVRGGF
LDGAAGFDASFFGISPREAQAMDPQQRLVLEVSWEAFERAGIEPGSVRGSDTGVFMGAYP
GGYGVGTDLGGFGMTSVAVSVLAGRVSYFFGLEGPAMTVDTACSSSLVALHQAGSALRQG
ECSLALVGGVTVMPTPQTFVEFSRQRGLAADGRCKAFADAADGTGFSEGVGVLLVERLSD
AQARGHNILAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALANAGLAGAEVDVVEAHGT
GTTLGDPIEAQAVIATYGQDRDRPVLLGSLKSNLGHTQAAAGVSGVIKMVMALRHDAVPA
TLHIDEPSRHIDWTAGAVELVTENQSWPVLGRPRRAGVSAFGISGTNAHVILESAPATDT
PAPAVTTGMVPLPISARTVPALADLEDRLRAYLTTTPETDLPAVASTLAMTRSVFEHRAV
LLGEETVTGIAVSDPRVVFVFSGQGSQRVGMGEELAAAFPLFARLHRQVWDLLDVPDLEV
DDTGYVQPALFALQVALFGLLESWGVRPQAVIGHSVGEVAAGYVAGVWSLEDACTLVSAR
ARLMQALPAGGAMVAVPVSEEQARAALVDGVEIAAVNGPASVVLSGDESAVLQVAEGLGR
WTRLSASHAFHSARMEPMLEEFRQVASQLTYQEPRIAMAAGEQVTTPEYWVRQVRDTVRF
GDQVAAFGDAVFLEIGPDRTLSRLIDGIATLHGDDEQHAVVTALAELHVQGVPIDWSAIL
GVNPARVLDLPTYAFQHERYWMVSTGRVGGEGHPLLGWGVPVAEAGGRLYTGRVARQDGP
VLPVAAFVEMAFAAAGGRPIRELSVDALLYIPDDGTAELQTWVSEHRLTIHARYRDTEPW
TRLATAALDTNEPATTHTPHPGLITTALTLTGDEAPAIWHDLTLHTGNATELHTHITPGD
DGTLTITATDTTGQPVLTAHTATPTTIPVHTPTTPADDLLTLTWTQIPTPGPGDPTDIAV
CTALPEPDGDPLAQTRTLTAQVLQSIQASLAGEDRPLVVHTGTGLASAAVSGLVRSAQSE
HPDRFILVESDDETLTPDQLAAAAGLDEPWLRITGGHYEVPRLTKTTTTAAATTVSEPVW
NPDGTVLITGGSGALAGILARHLVTERSVRHLLLISRSTPSTTLINELTALGAHIETAAC
DVSDRDALAHVLDGVDLTAVFHTAGALDDGVVESLTPQRLDTVLTPKADGAWHLHELTRD
RDLAAFVMYSSAAGVMGAAGQGNYAAANAFLDALAEHRRADGLPALSLAWGMWDDTDGMT
ASLSGTDHRRIRRSGQRAITPEHGMRLLDKASGRSEPVLVATAMNPIPDTDLPALLRSLY
PKTARKSQPIQELSPEALLKIVRDSAAMMLGHPNTDAIAATTAFRDLGVDSLIAVELRNS
LAKATGLRLPATLVFDYPTPTVLAGRLGELLAGVAPQRHATVRTATASDEPLAIVGMACR
LPGGVSTPEDLWRLVESGTDAITDFPTDRGWDTDTLFDPDPDTPGKTYTVHGGFLDDVAG
FDASFFGISPREAQAMDPQQRLVLEAAWEAFERAGIEPGSVRGSDTGVFMGAYPGGYGIG
ADLGGFGATAGAGSVLSGRLSYFFGLEGPAMTVDTACSSSLVALHQAGSALRQGECSLAL
VGGVTVIANPQIFVEFSRQRGLAADGRCKAFADSADGTGWSEGVGVLLVERLSDAQARGH
NILAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALANAGLAGAEVDVVEAHGTGTTLGD
PIEAQAVIATYGQDRDQSVLLGSLKSNLGHTQAAAGVSGVIKMVMALQNGVVPRTLHADQ
PSRHIDWTAGAVELVTENQPWPELDRPRRAAVSAFGVSGTNAHVILESAPAQPALPTDSP
ATGIPVSAVAAGVVPLPISARTVPALADLEDRLRAYLTATPETDLPAVASTLAMTRSVFE
HRAVLLGEETVTGIAVSDPRVVFVFSGQGSQRVGMGEELAAAFPLFARLHRQVWDLLDVP
DLDVDDTGYVQPALFALQVALFGLLESWGVRPQAVIGHSVGEVAAGYVAGVWSLEDACAL
VSARARLMQALPAGGAMVAVPVSEERARAVLVDGVEIAAVNGPASVVLSGDEAAVLRVAE
GLGRWTRLSASHAFHSVRMEPMLEEFRQVASRLTYREPRIVMAAGEQVTTPEYWVRQVRD
TVRFGDQVAAFGDAVFLEIGPDRTLSRLIDGIAMLDGDDEVRAAVAALAVMHVQGVGVDW
PAILGTTTGRVLDLPTYAFQHERYWMANAVEGHPLLGKVEHPLLGSVMALPNSDGVVLTG
RISLATHAWLADHVVRGTVLLPGTGFVEMVARAAAEVGCGVIDELLIEAPLLLPEHGGVH
LSVSVGEADGAGRRPVTVFAQADDAEVWVRQVTATISPAGPAVSLPELEVWPPVQAEPVD
VSNFYERLARADWQWGPAFQGLQAAWRDGDTIYAEIALADEEAREADQFLVHPALLDAAL
QTSVLKTPDDLRLPFSWNQIEFHATGAAILRVAVTPVADRWIVHAADSTGRPVATIGALV
SRPVTAETLGSNTDDLFALTWTEIPAPGPGDGADVVVCTALPEPDGDPLAQTRTLTTQVL
HSIQASLTGEDRPLVVQTGTGLASAAVSGLVRSAQSEHPDRFILVESDDETLTPDQLAAT
AGLDEPWLRITGGHYEVPRLTKTTTTATTTVSEPVWDPDGTVLITGGSGALAGILARHLV
TERGVRHLLLISRSTPSTTLINELRELGAHVDVAACDVSDRDALARVLDGVNLTAVFHTA
GALDDGVVESLTPQRLDTVLMPKADGAWHLHELTRDRDLAAFVMYSSAAGVMGAAGQGNY
AAANAFLDALAEHRRADGLPALSLAWGMWDDADGMTASLSGTDHRRIRRSGQRAITAEHG
MRLLDKASGRSEPVLVAAVMNSAGEGEVPALWRTLHRPVARRAATTNGRPADLTPEALLK
VVRDSAAMVLGHASADTVPAATAFQELGLDSLIAVELRNSLAKATGLRLPATMVFDYPTP
AALAGRLGELLAGETTPATAAVVRRATASDEPLAIVGMACRLPGGVSSPEDLWRLVESGF
DAITGFPTDRGWDVDNLYDPDPDAPGKSTTLHGGFLDDVAGFDASFFGISPREAVAMDPQ
QRLAMEVSWEAFERAGIEPGSVRGSDTGVFMGAYPGGYGIGAELGGFMLTGRAGSVLAGR
VSYFFGLEGPAMTVDTACSSSLVALHQAAYALRQGECSLALVGGVTVMPTPVMFVEFSQQ
QNLADDGRCKAFADSADGTGWSEGVGVLLVERLSDAQARGHNILAVVRGSAVNQDGASNG
LTAPNGPSQQRVIRSALTSAGLTTADVDVVEAHGTGTTLGDPIEAQAVIATYGQDRDQPV
LLGSLKSNLGHTQAAAGVSGVIKMVMALQNGVVPRTLHVEEPSRHVDWMAGAVELVTENQ
SWPETGRARRAAVSSFGFSGTNAHVILESAPAQPTLPMDTPAPTVTTGVVPLPISAKSLP
ALTGLEDQLRAYLTTTPETDLPAVASTLATTRSVFEHRAVLLGEDTVSGTAIPDPRIVFV
FSGQGSQRVGMGEELAAAFPLFARLHRQVWDLLDVPDLDVDDTGYVQPALFALQVALFGL
LESWGVRPQAVIGHSVGEVAAGYVAGVWSLEDACTLVSARARLMQALPAGGAMVAVPVSE
EQARAALVDGVEIAAVNGPASVVLSGDESAVLQVAEGLGRWTRLSASHAFHSARMEPMLE
EFRQVASRLTYQEPRIAMAAGEQVTTPEYWVRQVRDTVRFGDQVAAFEDAVFLEIGPDRT
LSRLIDGIPTLHGDDEQHAVVAALAELHVQGVPIDWPAILGTTTGRVLDLPTYAFQHQRY
WAASTDRPAGDGHPLLDTVVALPGADGVVLTGRISLATHAWLADHAVRGTVLLPGTGFVE
MVARAAAEVGCAVVDELVIEAPLLLPASGGVQLSVSVGEADDAGHRPVTVHSQADETEAW
VRHVTATISPSGPIVSLPEFEVWPPAQAEPVEVARFYDELAAAGYEYGAAFQGLRAAWRA
GETIYAEVVLAEDQTLEAARFTVHPALLDAALQANILNASGDLRLPFSWGQVQFHTTGAA
TLRVAVTPVADGWTIQATDDAGRPVATVGSVVARPVAGLGATAEDLFALTWNEIPPPGQG
GRTVGRFEDLADDGPVPELVVFTALPDVDADPLVRARALTARVLEAIQQWLGEPRFADST
LVVHTGTDLASAAVSGLVRSAQSEHPDRFILVEGDSSPVAIGLDEPWLRVDGGRYEVPRL
IRLSAEPVQEAVWNPDGMVLITGGSGALAGILARHLVAENKARRLLLVSRSVPDDALISE
LTELGAEVGTAVCDVSDRAALARVLAGVPSLTAVIHTAGVLDDGVMESLTPQRLDTVLRA
KADGAWHLHELTRDRDLAAFVMYSSAAGLMGSPGQGNYAAANAFLDALAIERRAEGLPAL
SLAWGFWEETTGLTANLTGADRDRIRRGGLQTITAERGMRMFDTATQHGEPVLLAAPMAP
VRDGEVPALLRSLHRRATRRGTTADASAQWLAGLAPEEREGALMKVVRDTAAVVLGHADA
GTIPVTAAFKDLGLDSLTAVELRNSLAKSTGLRLPATMVFDYPTPASLAARLDDLMNPRV
SSTALLAELDRIEGMFDSVTFDEKQASLVKDRLSAALGKWQQISRSADVATVALANADAG
EILDFIDREFGNPTI
>A0A2K8QXP5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MSGTEEKLRQYLKRVTVDLGQARQRLREMEERSQEPVAIVSMACRYPGGVGCPEELWELV
ASGGDGITAFPTDRGWDLDGLYHPDPDHPGTSYVRHGGFLGGTDRTDGTDRFDAEFFGIS
PREALAMDPQQRLLLEVSWELFERAGVDPVMMKGSRTGVYAGVSSQDYLSRMPRVPEGFE
GYATTGSLTSVVSGRVAYTFGLEGPAVTVDTACSSSLVAMHLAAQALRQGECDLALAGGV
TALTTPTAFAEFSRQRGLAPDGRCKSFAAGADGTGFSEGVGLVLLERLSDARRNGHRVLA
LIRGSAINQDGASNGLTAPNDVSQERVIRQALAGARLAPDQVDAVEAHGTGTSLGDPIEA
HALLATYGQDRPGERPLWLGSLKSNIGHAQAAAGVAGVIKMVMALRHETLPVTLHIDEPT
PHVEWEGGGVRLLTEPVPWPTGERPRRAGVSSFGISGTNAHLILEQAPEPSPPALSKEAE
PEHPAATTPEESGTAVPWVLSARGARALRGQADALVRRMADEPGSSIADVSWSLATTRSV
FDHRAVAVGETRAELVAAVEALATGGTHPGLVHSGGAAVAGELGPVLVFPGQGSQWPGMG
AELLSTSAVFAARVAECERALAPYVDWSLTDVLRGADGAADLGRVDVVQPVLWAVMVSLA
AVWAGHGVRPAAVIGHSQGEIAAAVVAGALSLEDGAKVVALRSKALRRLAGGGAMASLGV
SRERARRLLAGLGDRAAAVGVAAVNGPSSTVISGPPEQVANAVAACREAGDRARPIEVDY
ASHSPQVDEIADELAQALAGVRPVASTVAFYSTVTAGRIDTTGLDTGYWVANLREPVRFA
DTVQALLADGHRVFIESSTHPVLTVGMQESFEEAGVEAVTVPTLRRDHGGRERLLQSLAL
AFTAGVAVDWTTLHPTGPAAPRTVELPTYAFQRERYWLADLVSFDTASPADEEESGFWAA
VEGEDLGALSEALNLPDGTGHRTSLGTVLPALSTWRRGRRERSAADSWRHRVEWRPVPDT
APTTRGSWLVVHPKSASDGWTDACVRALGADGGQVRLLELDGDTDREGLAALLRSRYAEE
TPPTGVLSLLALDEDTPPLPGVAPGLTGTLTLLQALVEAAVPAPLWCATRGAVSIDDSDP
LDAPHQAQLWGLGRVAALEHPDRWGGLVDLPASPDSLDARRLCALLTGACGEDEAALRPA
GAYGRRLIPDPIGGRAPRRTWKPRGTVLITGAADGPAAHVARRLAADGAKHIVMLGPGGG
DAPAAVELKAELDALGTGLTVADHAPADREATAHLLERVAEASGRIGTIVHTAASGELTP
LMELTPRRLAEEIRAHLDDTGRPLDELCDMGPEDTVVYFSTVAASWGSKDHGSYAAATAC
LDALARRDRAEGRPTISIAWGLWDLPYGGDATDVPYGGDTPDAPYGRDTPDTPDTPDTPD
TAETPSAPHTERSRRQGLSPLDPRLALTALRQALDHDDPSVTIADVRWERFAPLFTLARP
SRLFDGVPAARQAIETARGPVEDTGGDEASALRRELGALPEDERVERLLALVRAHVAAVL
HYPAPESVEPDRPFKELGFDSIAAVELRNRLRAATGLSLPTTVVFDYPTPRTLAGHLLTE
VDPGEAGAAAHPVSGHLDELEAALAGLSAGDPRRAGLVNRLQALVWKYGATARESDEPEA
DEQDLTAATADEVFALIDRELGV
>A0A2K8RA61|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MASANEEKLLDNLKWMTTELRRTRRRLTEVEADAQEPIAITAMSCRFPGGVGSPEDLWQL
VAEGGDAISGFPADRGWDIEGLADPDPDRKGTFYNSGGGFLDGVAEFDPGFFGISPREAL
AMDPQQRLLLETSWEAFERAGIDPTSVKGSRTGVYVGAAAMGYGSDVQGAPQELEGLLLT
GGATSVLSGRIAYTFGLEGPAATIDTACSSSLVALHWATQALRQRECSLALVGGVTVMPN
PDVFVEFSRQRGLAPDGRCKSFAASADGTGWSEGVGVLLVERLSDARKNGHPVLAVVRGS
AVNQDGASNGLTAPNGPSQRRVIRQALENARLSAAEIDVVEAHGTGTTLGDPIEAQALLA
TYGQERPEGRPLWLGSLKSNLGHAQAAAGVAGIIKMVMAIRHGVLPKTLHVDQPSPTVDW
TAGEVSLLTEARPWDETGRPRRAGVSAFGVSGTNAHTILEQAPAPEDFPAPDGDTTPAAN
AAKVTAAVLPWTLSARNAAALRDNARRLASHLDREPALSTADVGHSLATGRAALERRAVI
VGEDRAGLTAALEALARGESAPGLVEGTVAEGETAFLFTGQGSQRLGMGRELYDAYPVFA
EALDAVCAELDPHLERPLKTAVFGDDAEALDRTGFTQPALFAIEVALFRLVEAWGLKADY
LSGHSIGELAAAHVAGVLSLADAAKLVAARGRLMQELPAGGAMIAVQASEDEVAPLLTER
VSIAALNGPTSVVIAGDEDAALEIAAGFEARGRKTKRLTVSHAFHSPRMDGMLDAFREVA
RGLSYEAPKIPIVSNLTGGVVSAEEITSPDFWVRHVREAVRFLDGVRTLEAKGVTTFIEL
GPDGVLTAMAQECVTGEDAGFIAALRKDRPEAEALTTAVARAHVRGVAVDWAAYFAGTGA
NRVDLPTYAFQHERFWLEPGAASVGDVASVGLELAGHPLLGATVPLAESDGLVFTGRLGL
DTHPWLADHVVRDAVVLPGTAFVELAVRAGDQVGCDLLDELTLHAPLVLPAHGGIRLQLT
VGAPDGAGRRSLTVLSRAEDAPAEEPWTRHADGVLASGAPRPSFALTAWPPQGAEAARTE
ELYAALADGGLRYGPLFRGLTAAWRRGDELFAEVRLDESTASEAQAYGLHPALLDSALHA
LGLGDGDDQGRLPFAWSGVALYASGASALRVRLVLRGADGVRLEIADSAGAPVAAVDSLV
LRAVSAEQVRAARAAYHESLFRVEWIELPAGAGAGASGGGRWAVLGTDAFGLGATAYADL
AELGEAVDSGMALPEYVVVCPALERPGAAIQARPALEDGGPGRSPGGVQGAEPLHAAEPH
IDAAGRGGVGEGPSLATTAHQATTQVLGLLHQWLADERFATSRLVFMTLGEGEPVRDPAQ
SAVWGLLRTAQAENPDRFVLLDIDGQDTSLAALPAALAAGEEQLAVRAGVVRIPRLARVP
VAEEAGMAADFGAAGTVLVTGASGSLGGLVARHLVAERGVRHLLLVSRRGERAPGAAELA
AELTELGAEVVWAACDVADRSALAATLATVPAEHPLTAVVHTAGVLDDGVIGSLTPERVD
HVMRPKVDAAWNLHELTRDLDLTAFVLFSSASGVFGTPGQGNYAAANAFLDALAAHRRAE
GRPAVSLAWGPWAGAGMAGGLDEADISRMRRAGLPPLSPAEGLALLDSALTTDEVAPVPM
RVDAVALRAQAAAGALAPLLRGLVRVPVRRAVDAAAGGGSALAERLAGLSEAERDRLLLD
LVRTQVAAVLGYAGPQAVEEGRAFKDLGFDSLTAVELRNLLREATGLRLPPTLVFDYPTS
TALAGHLREEIVGDTAAAIVPDRVLSAVDREDPIAIVAMSCRFPGGVRSPEELWQLLLAG
EDAITPFPADRGWDLATLYSDDPDREGTSYTREGGFLHDVADFDASFFGISPREALAMDP
QQRLLMETSWEAFERAGIDPATLRGTSTGVYIGSNDRDYLTLWLNEPQGLEGHLGTGNSS
SVASGRLSYAFGLEGPAVTIDTACSSSVVALHLAAQALRGGECSLALAGGVSVMSTPGAF
LEFSRQRGLAADGRIKAFSGDADGTNWAEGAGVFLVERLSDARRNGHPVLAVLRSTAINQ
DGASNGLTAPNGPSQQRVIRQALANAGLSPADIDVVEAHGTGTALGDPIEAQALLATYGQ
DRPEGRPLWLGSAKSNIGHTQAAAGAAAIMKMVMAMRHGVLPRTLHVSEPTPHVDWSAGD
IELLTEARPWPETGRPRRAGVSSFGFSGTNSHAIIEQAPAANAVSAPAPERSLPVLAWPV
SARTEDALRDQAARLRPSVDADAGAGTPRPLDLAYSLATSRAALEHRAVLLGRDGDLLGE
QLAALAEGRDATGLVEGSVSGGKLAFLFTGQGSQRLGMGRELYDAFPVFAEALDAVCDEL
DAHVERPLREVLFGEDAEALDRTGFTQPALFAVEVALFRLVEAWGLKADFLSGHSIGELA
AAHVAGVLSLADACTLVAARGRLMQELPAGGAMVAVQASEDEVAPLLTERVSIAALNGPN
SVVIASDEDEALAIAAAFEAQGRKTKRLTVSHAFHSPRMDGMLEAFREVAEGLTYEAPRI
PIVSNLTGTVVSAEEITTPDFWVRHVREAVRFLDGVRTLEAQGVTTYVELGPDGVLTAMA
QECVTDADAAGFAAALRKDRAEAETVTAALAQAYVRGAEVDWAGYFAGTGAHRVDLPTYA
FQRRRYWPDALETGARAEGAVDTVDARFWEAVESEDWESLATELRVEGDQPLSAVLPALS
SWRRAQRERSAADGHLYNVVWKPRPQGPSGSPAPSGTWLTVVPASHADDPRIAAVADDLT
RRGVRVVRVELDAADTDPATVADRLAAATADGPVAGVLSLLALDERPHPEHPAVPVGLAL
TGALAEALARRGDDAPARLWCATRGAVSTGGADRLDSATQAQVWGYGRVVALEQPERWGG
LIDLPETVDDRALDRLAAVLAGSGDEDQVAIRTTGVFVRRLAPAPRTAATSAAEPWTPRG
TVLVTGGTGALGRHVARWLAHNGAERVVLLSRRGPDAPGAAEIVAELSGTDTAVSVEACD
VADRDALAVLVEKLAVGGTPVRAVVHSAGISQEPGTGTELPEFARIVAAKTTGAVHLDAL
FGEDADPLDAFVLFSSIAGVWGSGGQGAYAAGNAFLDALAEQRRARGLTATSVAWGPWAD
GGMAAEGDAEEQLRRRGLPPMAPELNMVAFQRVLSREETAVTVADVDWERFAPAFTAARP
RPLIDDVPQVATVLRGGGEGESADTAAKDGASALRERLAGLSGADREDAVLEVVRSHVAS
ALGHASADEVEARRAFNELGFDSLTAVELRTRLGAATGLKLPASLVYDYPTPAALAEHLL
TELIPDGPGHGPGHGYTPAYADTDPQDAELRRTLATIPMSRIREAGLLDTLLRLADPQAT
TSDPSRVEDDAESIDEMDVQHLIDMALDLDSLDGNES
>A0A5B7ULK0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MGECGAALEPYVGWSLVEVVRSGVGFERVDVVQPVLFAVMVSLARLWRVFGVVVDAVVGH
SQGEIAAAVVAGGLSLEDGARVVALRSRAIVRLAGSGGMVSLALSSAEVEERLAGWGGRL
SVAAVNGPSAVVVSGDGDALGELVAGCEAEGVRARRIDVDYASHSAHVERIEAELLEALK
GIAPSSSEVPLFSTVTGEWLDTSVMDGGYWYANLRRTVAFEPAIRALAEQGFGAYVEVSP
HPVLTMAVEATLESAESTAVVLGTLRRDEGGLERMLLALGQAHVHGLSVDWAPLFEGTDA
TRVELPTYPFQRERYWLGPQESAAPAPDTDDLWEALVREEPARLAETLKVTPQALDEVLP
ALSAWRAERARERSVDAWRHRVAWQPLELPPGSVPEGRWLAVCPEAVRPEAVRPEEPAYA
EGAPYAEGAADPEAGSADDIVRGLRALGLDLAVVTARGPGQGRAGLAAALADAVAERPVA
GVLSLLADERRPHPDHTDLPGGLALTLALVQALGDAGIDAPLWCVTRGAAVVGAGERPGP
SAHAAVAGLGRCVALEHPDRWGGSADLPAEPDERALRRLCAVLASVTDEDQVAVRSTGVH
GRRLLPAPVTRGGTPAVEEGFGTGTVLITGGTGGVGAHVARWLAAQGAGQLLLVSRRGPG
APGAAALRAELAAAGAAVTVAACDVADPGQVTALLDALPREHPLTAVVHAAGVLDDGMVD
ALTPARLAVSLRAKATAARVLHEATAGLDLSAFVVFTSVMGVVGNAGQGNYAAANAALES
LAAARRAAGLPGTALAWGAWAAGEGMLDDGVAGRLRDRGLPSMDPAAAVTAIGRALAEDD
GHVVVADADWQRFAAATGPRATALLAAYTGPDGDGGERAPGSPDGTLRDRLAAVPAAERE
RFVTDLVRTHAAAVLRHPTPDAVRPERAFNDMGFDSLTAVELRNRLAAATGVRLPATVLF
DRPTPAVLAAHLLDELGETGAESPQDGAREAGRAPSAYDAEPIAVVGMGCRFPGGVERPA
DLWRLLAEGRDAVTDWPADRGWDAAGLYDPDPDRAGTTYCTRGAFVTDAAGFDAEFFGIS
PREALAMDPQQRLLLETSWEALERAGQDPEALRGRRVGVFVGTNGQDYMALAGADPEVSE
GHLLTGNTASVLSGRVAYVLGLEGPALTVDTACSSSLVAVHLAAQALRRGDCDQAFAGGV
TVMSTPRLFVEFSRQRGLARDGRCKAFGAGADGTSWGEGAGVLLLERLSDARRNGHPVHA
VLCGSAVNQDGASNGLTAPNGPAQQDVIRAALADAGLRADQVDAVEAHGTGTVLGDPIEA
QALQAVHAGRPAGRPLWLGSVKSNIGHTQAAAGVAGLMKMVLALQAGELPGTLHAEEPNP
HVDWSTGDVRLLTGRTPWPETGEPRRAGVSSFGISGTNAHVIVEQAPPADAPAAAGTPGV
PAAEASRADQPGPAAEAPRTEAPGPGSEAPRPDAPRTGVAVPLLLSARTPDALRAQAARL
RTYLGGHQPGHRPPDEGTAPGALADTAHALATRRAALDHRAAVLGRDPDAVFAALAALAE
GNSAGRLVTGHAGAPGRTAFLFPGQGSQRAGAGAELYRSEPVFADALDAVLTHLAPHLSP
DLELPLRDVMFAAPGTGAAALLDRTGCTQPALFALQVALFRLTEHWGVRPGLLLGHSIGE
LAAAHVAGVLDLPDACALVAARGRLMDALPGGGAMAAVEADEDEVRALLAEAGEPGVCVA
AVNGPRATVLSGDRAPVLRLAEAFRARGRRTKELAVSHAFHSARVDGMLDAFRAVARQMT
YAPPRIPVISNLTGARATADELCDPEYWVRHVRGTVRFLDGARTLLAESATSCLELGTGG
VLSGLVEACGTDGDACRAVPLLRDGRPETASFTGALAALHVRGAAVDWSVGCPDRLPRLD
DLPTYPFRHRRYWPAPRPAEAADAADARTYRVAWRALPEPAAAPALTGTWLLVVPGAAAS
TPLADACRAALAGHGAAVSVLAVPDGTDRAGLAALVPLGASGVLSLLATAPAGGTEATLL
LVQALGDAGGDAPLWCVTTGAVALDGRGPDRPEQAQVWGLGRVAALEHPGRWGGLADLAE
RPDAASLRRLCALLSGSVRTDGGCAEDQVALRADGLYGRRLLRAAPTPAYGSRTAADDAR
TTGSGEPGWSARGTVLVTGGTGGLGAHVARRLARDGAEHLVLTSRRGPDAPGATELAADL
EALGARVTVAACDVADRDALAELLDRLAADGDAVRAVFHAAGVTSDTRVADCTPALLAEE
TAAKVRGAAHLDDLLGEGPDAFVLFSSVSATWGSAGQAAYAAANAHLDALAERRRADGRA
AVCVAWGPWAGAGMAHGATGDGLRRLGLVPMAPEAALDALWRALERDDSGMVVADMDWPR
FAPAFRSGRDSALLAELPDAAAEPGRETDDALSGAAARWRDRLAALPPAERPRALTDLVR
AEAAAVLGHDAAVAVEAARPFHDIGFDSLTAVELRNRLAAATGLTLPASTVFDHPTATAL
GGHLHAELTGATPAPQDEPVRPATTDEPLAVVGMACRFPGGVRGPEDLWDLVAGERDAVG
PLPADRGWPLDDLYDPDPEREGTFYTTGGGFLDGAGDFDAAFFGISPREALAMDPQQRLL
LETAWEALERAGIDPGSVRGSQGGVYLGVAAQGYGTGPQDPAAAVEGHLLSGTVTSVASG
RIAYTLGTEGPAVTVETACSSSLVALHLAGQALRAGECSFALVGGAAVMASPDVFVEFSR
QRGLAPDGRCKSFAAAADGTGWGEGVGMLVVERLSEARRRGHPVLAVVRGSAVNQDGASN
GLTAPSGPAQERVLRRALAAAGLTGADVDLVEAHGTGTVLGDPIEARSLIAVYGQDRPAE
RPLWLGSLKSNIGHTQAAAGVAGVIKTVMALRHGLLPRTLHVDMPTTEADWSGGAVRLLT
EARPWDDTGRPRRAGVSSFGMSGTNAHAVIEQAPDEPPLEPAAPAPAVDPIATDAVALPL
SAASAPALRAQARRLREHAEAAPALPLTDLAHALATTRTAFPHRAAVTGRTRDELLAALA
ALAEGAPAPGATTGRAGEARTVFVFPGQGSQWPGMARELLHSSPEFAARITACAEALAPH
TEWSLLDVLREVPEAPSLERVDVVQPVLFAVMVSLAEVWRSYGVEPAAVVGHSQGEIAAA
CVAGALTLKDAALVVALRSRELRRLAGRGGMVSLAAPEEHVRELLLPYDGRIGVAAVNGP
GAVVVAGAPDALTGLQADCERAGVRARRLPVDYAAHSAQVADVGDALRTALAGVRPRPSR
IPLYSTVTGDVIDGTALDAAYWYRNLREPVEFARTTETLLAAGHDLFVETSPHPVLTAAL
TGTAERAERPVAAVGTLRRDDGGTDRLLTALAEAWAHGAPLDWAAALPRPARTHVPLPTY
AFQHERYWLATPGRTAAVAATAPAQAPAPVPNGDPAAELAARLAPLSGTDRRRAVLDLVT
AHAAAVLGHSGGAAVEARRPFTAAGFDSMLAVTFRNRLGEATGLRISPTAVFDHPTPAAL
ADHLHQRLCAASAPDRPDRPVHEHLDGLAAALAAAGPDTPGADTIGTRLRDLLRAWNDRV
PQDGSGVDGAPAVDTATADELFELLDNNYGA
>A0A3S4TLA6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium chitae|TrEMBL
MTRIPSWPDGRVPVLLSAHAEDLIAADARAIGRYLGGGTEVGVAEVAAQLLRTRRIRRYR
TVVRAAGLTELTAGLDAVARAEAHPLVATATEASAPRVAFVVPGQGGQHPGMGADAYRAL
PGYRDAVDTCCAAFAAADRATPLRYLTEVDDPESFAEIEIQGAQFTHAVGLAAVWRHHGI
VADLTVGHSLGEIAAAYLAGVIDLPAAIGVVAARAGVVDKLTGDYAVAALGITPAAAREL
IAETPGWLELSVINASSAVAVSGEAEAVTAAVARVRERGQLGREITVNFPVHTSVLEPLR
NWVQAQLPKPDEGGRFAESPVQFIGGTTGAVVEPSTGFADYWYDNLRNTVRFDHAVQAAI
DCGATVFIELSGHPALLHAVAERAADSAVLVGTGHRDAPAAEQFSANLAAVAVADPTHRW
RELGADAPPASPLPHFPNAPMRATPLWAHREPLEPIAALTVAGETWRPLTEAPVRPAAAP
RPAVLPLGPESALAAALRTSLADAGVTETDPAEAEVLVLVAPDAHDTDPVAAATTLTELA
EAGGLRLADRIGPACREVWLVTAGAEQVDATDPVPAPVPAALAAAVRSIGLEHPEQSFGH
VDVLGAEPPAAAAAVLDTVLAGPGTFALRWSAGAPRRYRRDLDLFGGSTVHAPDLPLDTG
LLDDVVITGAAGAIGTHYARHLAERGARRIVMVSRRGADPALITELGQRYGTEIVSAACD
LTDAAQLAAVAAALSGDGASLIVHAAGAATFGPATQLDGAAFAHTLAAKVTGLARLIEHW
PRRADCRMLLCSSMSAVWGGQGHAAYSAANRMLDVLAAQERAAGRRCTAVRWGLWQAGAD
GIVDTAEITQIERSGLRQMAPDLAIAASLRDYTLDPMVLAADPDRLRMFLAGVTGAAAET
PTATADSADLDGADTAQVVRTHLAAVLSAGPDDLDLSASLFDLGVDSLLALDLRKRLKRS
LGHTVGLARLLSGITGTELVSDLDAASSTTR
>G0PUE2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MANEAKLREYLKKAIADTRQAQHELQEVQGAASEPIAVIGMACRFPGGVTDPEGLWRLVA
DGRDGMTDFPVNRGWDNEGIYDPDPEAVGTTYVRTGGFLHDADAFDPEFFGISPREATAM
DPQHRLLLETAWETLEDAGIAPQSLHGSKTGVYTGVMYHDYSSRVSEVPAALEGLIGPGN
AGSIASGRISYTLGLEGPAVTIDTACSSSLVATHLAVQALRTGEVSYALSGGIAVMATPE
TFVEFSRQRGLAADGRCKAFSGDANGTIWGEGVGLLMLERLSDAVRNGHTVHAVIRGSAV
NQDGASNGLTAPNGPSQERVIQSALKNARLSVSDVDVVEAHGTGTTLGDPIEAQALLATY
GQGRPADRPLHLGSLKSNIGHTQAAAGVGGIIKMIMAMRHGTLPRTLHVSQPTPHVDWTT
GAVTLLTENQPWPELDRPRRAAVSSFGISGTNAHLILEQPTPTPATPATTEPIPYPVSAK
TPQALQAQITALQHHLTEHPELAPADIAHTLNHRTQFDHRALLLGTEELTRGAVGTGRLA
YLFTGQGAQHSGMGRELYETYPVFREALDAALTALGIQDEFFTGDLDRTRLTQPALFALE
TALYRLYESWGITPDHLVGHSIGEITAAHVAGILTLPDAAKLVTARATLMDALPHTGTMT
AIEATEEEITPHITDGVSIAAVNGPTSVVISGDTDATQRITEHFRTQGRRTKALTVSHAF
HSHHMEPMLDDFRTVARTLTYSAPRIPIVSTVAVDSDLTDPDYWVTQIREAVRFHHAVQE
LETRGVTTFIELGPDGVLTAQAQQSAEGTFTAALRRGRDETTTALTALGTAYVHGRTLTT
PHGAQLSDLPGYAFQRQSYWMEAPRSAQNAAALGQTSVEHPLLSSLIHAVDSETTLFTGQ
ISRSSHPWLADHTVMGNVIVPGTALIELAIHAGDRAGFDTVDEMLIAAPLFLTDEAVQLQ
VALKDNTVSIHSRSGDRAWDLHATATLSTTAASAETLAWPPQGQPVPIEDVYPALERIGL
GYGPAFQGLTAAWRSGDALFVEIALPEAVHDAAFGIHPALLDSALHAYAHQHAVDGGISL
PFSWNGVRLHASGATALRARITPAGEGGLALHAVDHAGQPVVSVAQLATRPVSADQLQMR
TSSAEQLLVPSWQPLTLPVDAPEAPHQVLSVPRGGELHEVTEYVLTALREWLALDTDDVL
VVHTHDAVDTGTPDLAAAAVWGLVRSAQTENPGRILLLDGDFDATVIGGAVAVEENQLLV
RGDEVRAARLIRPDTDALLPVPGGPWQLVSTGAGTLETLAITADERVSRPLFPGEVRLEV
RASGVNFRDVLIALGMYPHDPLPPLGGEVAGIVIEVAPDVTTMAVGDRVFGLAEGTFSRQ
AVGDHRALHAMPSCWTFTQAATAPIVWMTALLGLKNIAGLSAGEKVLIHAGTGGVGMAAI
QLARHYGAEVYATASLPKWDVLRSLGVDDRHIADSRTLDFEEHILRETGGSGVDVVLDSL
AGDFVDASLRLLPRGGRFLEIGKTDIRDADEVALRHTGVAYTAYDLNASDPDTLQALLAE
LYDLFERQVLTALPVRAWPVPQAPAVFRYMGQAKHTGKIALTVDRPLDPEGTVLITGGTG
TLGAILAKHLVERHGVRRLLLTSRRGHAPELAAELTGLGAEVTVAACDASDREALAALLA
GVENLTGVVHTAGVLDDAMVTNLTPEQLHVVLRNKADAAWHLHELTRDRDLAAFVLYSSM
AGTLGGPGQGNYAAANAYLDALAHHRRERGLPAVSMAWGLWEDASAMSAHLTATDLARMA
REGFPAISAAQGVEMFDAALTLGQAAVLTAPITLSSLRGEVAPVLRALVRTPSRRTASAR
TADTDALASALAARDEAGRLELLLGIVREHVAYTLGHSGGDAVDPETPFKEIGFDSLTAV
ELRNRLSAATGVRLPATIIFDHPTAAAMAAFLRSKLTGGASAAAPVVRAVVTDDEPIAIV
SMACRLPGDVRTPEDLWRLVADERDAITGFPTNRGWDLDGLHDPERTRSRTSYISAGGFL
HDADRFDAAFFGISPKEALAMDPQQRVLMETSWELFENAGINPKALRGSRTATYVGLLGQ
DYAPRGPQAFDEVEGHVMTGISNAVASGRIAYAYGFEGPALTVDTSCSSSLMATHIALRA
LRSGECDLALAGGVTVIAQPDIFTEFSRQGGLARDGRVKSFGAGADGTSFAEGAGLLLLE
RLSDAVRNGHTVHAVIRGSAVNSDGASNGLTAPNGPAQERVIQEALASGGLVPADVDALE
AHGTGTVLGDPIEAQAVLATYGQNRTSPLLMGSLKSNLGHTQGAAGVAGVIKMVMAMKHD
LLPRTLNVDEPTPEVDWSTGSVALLAEARPWPAGDRPRRAGISSFGISGTNAHLIIEEPP
AHAPDSPGPSDSVGSPVEESSAAQPGPVPYLVSARTPEALTAQVARLERHLADHPELAAS
DVAHTLAGRARFDHRALLLGTEVLAGGTVGSGGLAFLFTGQGSQRTGMGSELYETYPVFR
EALDAALTALGIQDEFFTGDLDRTRLTQPALFALETALYRLYESWGITPDHLVGHSIGEI
TAAHVAGILTLPDAARLVTARATLMDALPHTGTMTAIEATEEEITPHLDDTVGIAAVNGP
TSVVISGDTDATERITEHFRTQGRRTKALTVSHAFHSHHMEPMLDDFRTTAEQLTYGEPT
IPIVPTAATHLAMTDPEYWVTQIREAVRFHHAVTALPEGTVFIELGPDPVLSAAAQQFVK
GSFAATLRTGQSEVTGVLTALGTAYVHGGSPVLPAGNTVELPNYAFQQQSYWLTDLGGPV
DAAGLGLLPGGHPLLGGEIRQADSDTVLFTGRVIGVEHGAATLLDLALHAADGGLAELTV
ESPLPSGEALLLQVAVDGTRLTIHSRADDTPWQRHATGTLATVESDTPGLTWPPNAVEAD
APADGVTQAWRDGDTFYAEAAKDATEHGIDPGLLTAVLQRGGVPVQPVHWRNVRLHRAGA
TTLRVRFDGGLLATDEDGVPVLTAEQVTTAPVSAAQHALFDLTWVPSAKSGVTGFDVLEV
PRFGELDGVLTTVLHALRSERSGPLVVHTHDAVHTEDPDPVAAAVWGLVRTAQHEEPGRF
VLVDGETVPAALPDDEPQVVVRGHETLVARLARITASAPAPDWHGTVLATGDAPFVRHLP
VKDVVTWTGDDPEELRQVLDAHDVTAVVHVPEPGAEELVAQLTPERLVKTVRAAADLARH
LHRLTEGRELVAFVLSSSMAGTVGRTGRGADAATAAYLEALARHRNAAGLPAIAVAWGSE
RSQELFDAAVTAGRPAVVANVLDPSAIRAAGPVPAVLRGLVKPLPQRGRTLAARLVGLDE
AARGAVVLEVLREAIAEVLGHDDPKEIEAEYPFSDLGFTSMTAVELRNQLFTATGLDLST
TLVFDHPTPAALAEVLLERLGPENRAHQAVQSDLDRLEASLAAASATTSPHAAAVANRLR
AMLAKWTEDPDENTDGEDENFASASAEDIFDFIDNQLGRSTN
>F8B6L4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Candidatus Frankia datiscae|TrEMBL
MSGDTLAQRRLADNPIAIVGMAGLFPNAYNYREYWQNIVDATDCTQDVPASRWNLDDYYD
PDPTVPDMTYSRRGGFIPDVDFDPLEFGIPPNQLEVTSVMQTLSLIVARDLLRDAGATES
DWYDATRTGVVLGVTGPVPLMHPLAARLSTPVLKEVVRSCGLSASDAEAIAAKYVQAFAP
WEENSFPGLLANVVSGRVANRLGLGGMNCTVDAACAASLSALRMAVAELVDGRAEMMIAG
GADTENSIFGYMCFSKTQALSKSGQIRPFDDAADGTLIGEGIGMIALKRLADAERDGNRV
YAVIRGIGSSSDGRSKSIYAPRAEGQRLALARAYADADCSPASVELFEAHATGTAVGDRT
ELSALTEALSEASGERHFAAVGSVKSQIGHTKGAAGTASLMKLALALHHRTLPPTINVEH
PNSAIDFTGGPLYVNTRTRPWIRDPDRPVRRAAASAMGFGGTNFHVVLEEHTASEEHTGE
RRATTTLHRTARAHLWHAADTASLLELLRSGAEPDDSTQIPAEHARVGFVAADDETAQRL
LALAVEQLAAAPDAQQWTHPAGVFFRARALADLKVGALFAGQGSQYLDMGLEAVLNIPTV
AGAVDDANEAFAGADHRLGAIIYPPPVFDAELRQEQESRLRRTEYAQPAIGAISVGQFRY
LAELGLRCSGFLGHSFGELTALWAAGALDDADFFRLARARGEAMAPPAEDPDHDPGTMAA
VQATREQVIDILRAFPNVVICNHNAPDQVVVGGDTQAVGEVVQECKQRQLGARLLPVSAA
FHTSHVAHAVEAFGHAVSSARIGEPRQPVYANTAGVRYGPDVEANRRALTEQLLQPVEFV
QALEAIRADGCNVFVEFGPKQVLTALARRTLEAAGIVAVPTDAGPLGDSDVALKQAAVQL
AVLGAPISGVNRHDAPAWVAPKPRGMAVTLNGADYVPESRRAAYQAALNDGFRASTVTPA
VTSTNGVGGVGGDNVGSDNGFGLGAGIDADITDAHQAAQQVPVDAAVPSDLPTPDLSVLS
ADHAAPSAAAPSTAASSTATSLATVQPATAWPPAAGVAEPPAAYAHSVDAGEDVGLDDVV
AQHVALHSRYLESQLQVTEGLVEILHQQQPGVDAGGGAWLARAVESVKDQSLAIGQAHIR
ANEILSSLAEIERGGHRSPTVNGYPAPAPADFGPSAPPLPALPEQPRRTEIAAAPSPAPA
SAPTPVPAFAPASAPVSAPAPVPVPVPSAEAAPVSAAPAPTPADAAPPAPTDAAVSAGSV
DAGLLRSALVGVVAERTGYPPEMIDTGMDLEADLGVDSIKRVQILGAVQERFPQVPSVGP
ELLGELRTLEHIIDFLVSAAAPAPTGAAATAAPAAPSAEEQAPPVEQVARHPVELVGLPP
VDRIEQPYPAGPVAVVVHPAEQAGETFAAGLEEAGWTVTRVGLPAPGGDGTSDLAGWDGE
AVERRLSEALTDALGTTGRIDLFLTVLGGSDTRDHSVRQDTTEDRGVRQLADAVLVAKHA
SVPLATAARSGDRAAFVTVTRLDGGLGHRGGRGAAEALLGGVGGVVKTLAHEEPSIFCRA
LDIDPELGGDDALAVLLDEIADAATDTLEVGVDAARRRWTVIPAPYGSPRASTAVATGAT
VAPVAGTGAAATDAVPSASTVGAGDVLVVTGGARGVTASCVRVLGEHSQVEFLLLGRTAL
AAEPDWAAGVADADLKRAAIAALGAGGGRPPTPRQVDAVLRDIQAQREIRATLDALAGSG
SATAASYLQVDVGDAAAVRDALAAHRDRIMGVVHGAGTLADGLVRTKTADDVRRVFTPKL
AGLRNVLDALDGAPIRHVVLFTSVAGLFGNAGQADYAAANEALCRVAASLKREHPERHVT
AIDWGAWDGGMVAADLRELFHARGVELLAPATGARLFVEQFGAERVDDVCVLVGQRKALT
DGTGRAFTARRELTGIEDTEVLQAHRIDASPVLPATFGLGWLVNVLERAHPGLQVIEVSG
FEVHKGIVFDGAHSRAYQVEVPLAEARDGRLTVRAAVRAAVGGTGSGAGSAAGSGSALPV
SHYVGTFVLAEAPPAAPVAPGRPGEAVGSGPEDGVEIYTGGTLFHGPALQGIRRILQRSD
DRVVLECRLADQVVADGAFTGALHSPVLADILLHGPSVLGRWLTGLACLPLAVGRWEYFA
PLPDGEPFVVVLDDVRRAASSITVTVTASDPGGRVLQRLRDVSMIGTPDMAAKFAAAVRW
WLPGEGA
>A0A0N1FN62|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OV450|TrEMBL
MSNEEKLLGYLRRATTDLREARKRLAAAERRSSGEPIAVVGMACRYPGGVNSPDELWQLV
AEGRDGVSAFPEDRGWNTDALYDPEPGKPGRTITREGGFLYDAGDFDAALFGISPREALA
LDPQQRLLLETSWEAIENAGIAPHTLRGTKTGVFGGVMYHDYALGTEAAATTGGSLVTGR
VAFSLGLEGPAVTVDTACSSSLVALHLAAQSLNSGESTLALAGGVTVMTEPDMFLYFSHQ
RGMAADGRCKPFASAADGTGCSEGVGVLVLERLSDARRNGHRVLAVIKGSAVNQDGASSS
MTAPNGPSQQRVIRSA
>A0A1A8XY34|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Candidatus Accumulibacter aalborgensis|TrEMBL
MNPPDPARNEAAIAIVGMSCRFPGADDVTAFWRNLEQGVESISFFSEAELLAAHVDPALL
ADPAYVRAGAVIDPIDCFDATFFGYSPREASLIEPQQRIFLECAWEALERAGYTPASHGR
AIGVFAGSAMNGYLIYNLASRPDVAPALFDFQIQIGNDKDYLTTRVSYKLNLTGPSINIQ
SACSTSLVAVHVACQSLLNGECNLALAGGISVAVPHRVGYRYQEGGVNSADGHCRAFDAD
ARGTVLGSGVGIVVLKRLADALADGDHIHSVIKGSAVNNDGSAKVGYTAPSVYGQAAVVA
EALAMAAVDADEIGYIETHGTGTPIGDPIEIKALTQAFRETTDRQGYCAIGSVKTNIGHM
DVASGVAGLIKTTLMLEHRRIPPSLHYRRPNPEIDFAHSPFYVNAALADWTQAVRRAGVS
SFGLGGSNAHVVLEEAPARAAAAPSRPWQLIVLSARTATALERMRERLAAHLSHDPEQTL
ADIVFTLQTGRQRFAQRRIWVCAEQSSLTRTLLTADSQRSAGSVCELNDRPVVFMFPGQG
AQYLGMGRELYDSEPVFRAEVDLCVELLAPHLGHDLRHLMWSAPDADADAEPLQQTWIVQ
PALFVIEYSLARLWMSWGVRPTAMIGHSIGEYAALCLADVLSLADALRLVAARGRLMQEM
PPGSMLAVDQPESVLADLDARGLALAGVNAPGRCVLSGPTEAVAAWQRQLAAEGRQCQPL
HTSHAFHSAMMDPILARFAAEVAAIRLQAPRIPVVSNLSGTWLTAAQATDPAYYVQHLRR
TVRFADGIATVIADGDPLLLEVGPGRTLGTLAQLCSATSGAKGALWSMRHPQQEEPDQAM
LLATLGKLWLAGVTVDWAGFYADEKRRRVPLPGYPFERQRHWVEPGRLLAQAVTDDRPAP
RAAASKRPLADWFYQPFWQQTPLRDGGPAASGPWLVFTLGDGFGEYLAGELEQAGDNVIR
VLPGSQAGWSSARCFTVNPARRADYDALVEALAGAGKLPHSALHTWNLTPPPDHSPNPED
FARAQDLGFNSLLYLAQALGSRNHSEPLRIGVLGTAIHALTATELPLPERSTLIAACIVI
AQEYASLDTRCFDLLPPAAGSAAEQWLGHQIRIEMGSDAADAMVAYRDNIRWVQDYRPLH
LEPLAGTPGRLRQQGVYLITGGLGAIGYALAEELARSVQARLILTGRSALPDPGEWDHWI
ATHASSDPGSQRIARVRALQALGAKVLVVAADVADAGAMARAVNQARSRFGRIDGVIHGA
GIIAEEAFLAVQDTRPEHCGEHFRPKVEGLLVLHDLLRAEPPDFYVLLSSISSVLGGLGY
AAYAAANAYLDAYAAHQSHQAHQSGQPGPAWLTIGWDAWIPAATRTDQRSMGAIVSDLAL
SSEEGVDAFRRMLAADAGQQIIVSTTDLSTRIAQWVKRKPRAASSPQATTGIAPGVAYAS
EMQAAIAGIWRSALGVSDIEVQDNFFDLGGDSLLLMDVIARLKSAYGIVLNPREIMFQTL
AQLAAVCEERQMAKDKAQSASTGTAAVAAPQTLAEAEPGAQPQLKGGLFGALKRKIRG
>K9PTM1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Calothrix sp. PCC 7507|TrEMBL
MSAYSIDTALAELESLINSCEKDLIKFIEEKKVNSEKPMSINKINRKLQQNPIAIIGMAS
LFPQARNLREYWRNIVNKIDCITDVPSTHWSVEDYYDPNPRTTEDKTYCKRGGFIPEVDF
NPMEFGIPPSILEVTDVSQLLSLVVAKEAMEDAGYGESREFSRETIGVILGVAMAKQLGM
PLSARLEYPIWEKALKSSGLSDEDTQKIVEKIKSAYIKWDENAFPGMLANVVAGRIANRL
NFGGMNCVVDAACASSFGALKMAISELVEHRSDMMLTGGVDTDNTIMAYISFSKTPAVSP
SEHVRPFDAKSDGMMLGEGIGMIVLKRLEDAERDNDKIYAVIKGIGTSSDGRYKSIYAPR
KEGQVSALRRAYDDAGFSPATVGLMEAHGTGTMAGDPTEFGSLRDFFNEEDQKRQHIALG
SVKSQIGHTKAAAGAASLIKTALALHHKILPATINITEPNPKLNIKNSSFYLNTETRPWI
RADGEAPRRAGVSSFGFGGTNYHVVLEEHEAEQNRPYRLHNAPAEILLFADTPAQLVMKC
EETLGKLQSKEGDRHYAQLVQDCQNQEIPLAAARVGFVAETLQEACKFMQTSLDWLKLKG
SAASWEHPQGIYYRASGMALGGKVVALFSGQGSQYLEMGRDVVMNFPTLRRIYGYMDSLL
LKDNLQPLSQIVFPNPVFEESEKNAQVAALQRTEYAQPAIGVLSAGLYSILQQAGFRSDF
VAGHSFGELTALWAAGVLSDQDYFFLVKARGQAMAAPEDPDHDAGSMLAVKEEISKVEAV
VRHYPQVAIANFNSPTQVVLAGPTAEIAKVRQALHDQGYAAVLLPVSAAFHTPLIAFAQK
SFAIATKSVNFQTPKIPVFSNVTGKQYPQEAPAIQKILETHLSNSVLFKQEIENIYAAGG
TCFVEFGPRKILSNLVKDTLGDRPHITVTLNPSTQKNSDRSLREAAVQLRVIGMNLKNLD
PYQIPPTPPAPEDQKKKALTVKLNGISYKSEKTKNAFAQALQNGHQVKLAATPSPEFAGI
AADFATLAAATPTTPAIEGNGHKKTSVVPTLLEAGEQGEKSFPPASYQESKMPEKPVNYQ
QILESLEYLLKQFQQNQSENLQLHGSYLNHQIEYTKTFFQLMEQQNSVLANSKANTEIKP
VVMEGLQRSMMQFHAQQGETLRIHEKYLQEQVEYSKNFFQLIQQQYSQLLSGEKAGEQGS
RGEIQPASVAAPVWEIQPAPVVETPVVPAFTIAEIPPAPVVEIPKVAEIQPVPVVETPKV
AEIPPAPVVEIPKVAEIQPAPVASDLNLAELGKHLLEITSEKTGYPIEMLEMDMDMEADL
GIDSIKRVEILGGLQELYPNLPKPNLEELSEKRTIGQVVEYLESHASRSVSVDIAIQEIQ
QAVEVAPVVEPVVIPPVAAVVEPVAIPQAIPVNEIVAFTPEVETTATTDYADLGQTLLNI
TSEKTGYPVEMLEMEMDMEADLGIDSIKRVEILGTMQEMYPDLPKPNLEELGDLRTIGQI
VDYLQKLAAGSEKKKSQFEFDDEPIDIEHNVKRRPAKLKFLPPPDDLDFTLPEGHIGLIT
DDGSLTTSVVVQSLIERGWQIVVLSFPQSVVSTQAQLPAGVTRITLADLSEELLQHKLSA
IASNIGKIGAFIHIHPTLRVKNTIGYIEAEKAIVKQVFFIAKHLKKSLNDAAHYGRSCFC
TVTRLDGAFGFEHKVNYGVIGAGLFGLTKTLRWEWPKVYTRAIDLSPALDAKQSAQHIIA
ELHDSNLYISEVAYGSQGRVTLTTSAE
>A0A3N6GER5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI98-12|TrEMBL
MEREDLDSLSATLELDDTVLSSVLPALSTWRRGRSERTLLDGWRYRVTWQPVPVPEAAAD
GTDGPWLVLVPAGHGDPWTEALAGAFGESAVRLAVPAADEDGTAALLGAAAEGTAYAGVL
SLLAGTGTDGTARPDTLLRLLETAGIDAPLWCVTREAVCVGRSDAAADPGRAALWGLGRV
LALEAPGRWGGLVDVGHVADARTIRRLRAVLTTAAPAGTAEDQVALRTSGVFGRRLSRAD
APATDVTWRPAGTVLVTGRAEGFGGHVARWLAAHGAAEVLLAGPGDADEAVTTALRTEMA
AAGAVLTTVRHTDPADAAPLVEALAALAADRPLTAIVHTGDTGDTGDTGDTGAEDAPGIN
EARAAYEALVTAAGSRQLDAFVVFGSISAVWGVTGQGAGAAAGVCLDALVQQHRASGTNA
VSVAWGAWQGAGPEGLAAHLRANGLPAMDPARALDALAPAIGAGAADPAAPASVTVADVA
WDRFAPAFTRARAGLLLTGVPEARAALSDAGGDGADAGTAAELRERLRQSDPAERVRALL
ATVLTEVASVLGHADAGDVPAENAFKDLGFDSLTAVDLRNRLATATGLTLPATLVFDYPT
PTALAGHLLTELLGEDTAPGTGDLSARGAADADDPIVIVGMSCRYPGDVRSPEDLWAMLG
SGTDAIGGFPTDRGWDLDKLLHGDRDGRGRSVTREGGFLYDVADFDPAFFGISPREALVI
DPQQRIVLQAAWEALERAGIDPAALHGGDTGVFVGGGSGDYRPAVGQSGHVETAQSASLL
SGRLSYTLGLEGPSVSVDTACSSSLTALHLAAQAIRAGECSLALAGGVTVMSTPVGFVEF
GEMGALSPDGRCKPFSDAADGTAWSEGVGMLVVERLSEARRRGHEVLAVLRGSAVNQDGA
SNGLTAPNGPSQQRVIRKALAAAGLTPREVDAVEAHGTGTTLGDPIEAQALLATYGQDRP
EGRPLLLGSVKSNIGHSQAASGVAGVIKMVLAMRHGTLPRTLHAEKPSRHVAWDPDAVRL
LTEAADWPETGRPRRAGVSSFGASGTNAHVILEQAPAEPAAPARDARPAPDATGAVRTLP
VPLSGATADALTEQAVRLRDRLTAGAPELPAVADLALSLGTTRSAFEHRAVLAVAGRDDL
LDALTALVEDRAHPAALRDRATPGGRTAFLFPGQGSQRAGAGRVLYARFPVFAAALDEVL
AHFDQELERPLREVMFADEGTAEAELLDRTGWTQPALFALGVALYRLVESWGVRPDLLAG
HSVGEIAAAHVAGVLSLADACRVVAARARLMEALPAGGAMVAVRAGEEEVSPHLTDRVSL
AAVNGPDSVVVSGDEDAVTALAEEFAARGRKTRRLRVSHAFHSLHMDAMLQDFERVTRSV
SYTPPKLPLVSNLTGGPATDAQVCDPRYWVEHVRGAVRFGDGVRTLAVRGATRYLELGPD
GVLCGLAQETLDTLADEHRPAPAVVPALRTGRDEEQALIAAVARLHAAGQPLDWSALLDG
TGARRVDLPTYPFRRLRFWPDEAPAADAPAPDAGDAAFWAAVQDEEFDSLAGELGVDGEA
LLRVLPALRDWRRKHGDQATVDGWRQRIAWRPLNRATAGTPAGTWLAVVPADHAGHPWTT
AVLTALGTGAQLLEVAGQDRAGLAAALRARLDADGPFTGVVSLLAVAGEPGDGTGALAGG
VPVGAALTATLVQALGDAGTDAPLWCLTRGAAAVSPAETVAAPLQAAVHGLGRVTALEHP
RRWGGTVDLPLAVDARTAERLAAVLADPEGEDQLAVRPGAVFGRRLAAVRPETPRDWKPT
GTVLITGGTGALGARTARRLAGAGARRLVLLSRSGPDAPGAGELAADLRALGAEPVITAC
DTADRKALAAVLAAIPEDTPLTGVIHTAGVLDDGVVDALTPERFAAVFRAKVTSALLLDE
LTRAHDLEVFALFSSASAAVGNPGQGTYAAANAVLDALAEQRRAEGLPATSVAYGAWGGE
GMADGVRAAALARRTGIRPLDPDLAVLALRQVVTGSDPVAVVADVDPDRFVRAFTTVRPS
SLLAEMPAYAALKAAGASAGGDTATTGPSLRDRLARLPEGRRAQTVLALVRERAAEVLGH
FGTDQVGPDRAFRDLGFDSLGAVELRNQLGAASGLTLSATLVFDHPTPAALADHVLGQLL
PAGTSGAPAAAGADDEERAVRAALARLPVDRLRESGLLDQLLDLAGQNPAGSGTDQEATA
ADADESYDASIDAMDVDGLVQAALNGNPDEERD
>A0A3N6F2C9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-17|TrEMBL
MGTQVEEIVQALRTSLVENERLRQQHQRLVDERTEPIAVVAMSCRLPGGIRSPEDLWRLV
LDGEDAMSGFPDGRGWDAGWLRGLGDSGITPEGGFVHDADAFDPVLFGISPREALAMDPQ
QRLLLEAAWEVLERAGVDPTSVRGTDTGVFVGASSSGYSAGMYGDAEGSESFLLTGSAGS
VLSGRLSYTFGLEGPAVTVDTACSSSLVALHMAVRSLRGGECSLALAGGVTVMASPGAFV
EFSKQGGLAGNGRCKSFAAAADGTGWGEGVGVLLLERLSDARRNGHQVLAVVRGSAVNQD
GASNGLTAPSGPAQRRVIGQALADAGLAPADVDAVEAHGTGTTLGDPIEAQALLATYGRQ
RPAERPLLLGTVKSNIGHTQAAAGAIGAIKTVLALGHGVLPRTLHIDEPTPHVDWSSGAV
SLLTEAVAWPDTGRPRRAGVSAFGLSGTNAHLILEQAPDAEPTKAPDAPDAEAAGTPLPV
VPLLVSGRTDEALRGQAARLIDRLRDTPDVPLADLGRTLAVTRAALDRRAVLLAADHAAL
LRGLTAVAADKPGPGVVRGAVRVAGGTAFLFTGQGSQRLGMGAELHALFPAFAEALDAAC
ARFDPYLRTPLRAVMFGTDADLLDRTEYAQPALFAFEVALHRLLESWGVRPDAVAGHSVG
ELAAAHVAGVLSLEDACTLVAARGRLMQAMPAGGAMVSIEASEQEVRDSLAGRPDAALSI
AAVNGPAAVVVSGDRASVDEVVALWAARGRRHKELRTSHAFHSAHMDAMLAEFRSVAEGL
TFRRPEIDVVSALTGERLTADQAVSADYWTRQVRETVRFADAVRRLSDDSVTTFVELGPD
GVLTALARVCLADRTDARQPLLAAAQRRDRPAAHALFNMLAELHVQGVTVDWDAVFADRG
TRRVDLPTYAFQRQRYWPAPPAAHADVPEPVAEDGGFWSAVEHGGPAAVARLLDAPEEDE
AALRTVLPALAAYRRRHTRSTLTGDWRYRTAWEPVTVPESVALSGSWLVVGPDTAPVADV
TRALRARGAEVLCVPLAGADRDALADAVNRLWPDPALPPMAGVLSLEALAEPADGSCPDG
ALAATVALLQALGDNGVSAPLWCLTSGAVRAAGTDPAPDPVAAQLWGLARVVALEHPERW
GGVVDLPATLDEAALDRLVGVLGAADREDQLAVRASGVLGRRLVRARTEDREPVRRWTPH
GTVLLTGAADERAAHVAGWLAEQGADHVVLAGAGAEQAAVVEERVTAAGAKVTVLPDHVE
NCPDLSARIGQLARLSRLTAIVHIALPTAVGVPLAETEPAELARAVHAETGLARTLDGAL
TAPELEAFVVFSSTAATWGGGGFAARAAVGAAMDALVEARRERGLPGTSIAWVPWAGSPP
GAADERLRRRGVRALRPGPAVSALQQALDHDDTCVAIADIDWARFTPAFTAARPSALLTG
IPEARAVLAAPVTEAQPDDSPAALVGRLESCSPPDRYQLLLELVRSRAAAVLGHASAGYV
DIDRDFLEQGFDSLTALELRDALQAATGLDGLSGTLLFDHPTPSELARHLSAVLADGNTG
AEEGERVAAPAADKGPAAGNGGILGRLFRHTRSQGESTEYAKVLLRLAEFRPVYTDPADL
PRPATVVRLMSGRGQDTPGGRRAGSGGELPPVFCCCTMSMLSGAHEYARLAAGFRGSRSV
YALPHPGFADDEALPASYDVLMRTHADSVLRTAGDGPFVLTGHSGGAQLANSLAHELAAQ
GRPPAAVVLLDSYPMDSGVMAQWVPELLDGMLERDSAYTPMDDFRTTAWAAYLPLLHGVT
PQPVDVPTLLMRASTPLSEWTGEGDWRASWPLPHTAVDAPGDHFTLIGDHAADVARQMQE
WLRSEGC
>F1TGL0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
KAETENIRATELSVSHGFHSPMIEPMLKDYERILDEVDFHESKITIISGVTGQKADEETL
GKEYWLRHVMEPVDFYSSVKSCEESNIGIMLEIGATNTLCNMAKKIVTREDLLILSTLKR
GSSDWRSFQEAMTQLYIKGISINYEAYDKGYKRKRIALPLYPFNGKKYWQNQQVVENKAF
EIKPEEVPAIKPKKEYKLKEKVNHLLLDIIAGASKPISGQLSVYNTFMSMGLDSNSLIYT
GSEIEKRLDVVFYPSAFFEYNSIDAMSDFILKEYKENVLRYFNSVDNITTPSMEDVPESD
TNNKEKFKHKEAKVEKCLDDDIAIIGMSGQFPKAEELNTFWSNLSQGLDCVSDIPAFRLD
LDKYYDSNRNADKKTYLKKSGLLENVDMFDAEFFSISPKEAKDMDPQQRLFIQEAYHALE
AGGYGGNRLYESNTGVFVGVAHTQYKEDIPYINTFTPLGNHEAIIANRVSYFMNFNGPSL
VVNTQCSSSLVAIHLACRSIQNGECDQALAGGVMAVFSPIYYLSGSKLQAFSPDGSCKAF
DKEANGYVPGEGCGVLLLKSLKKALEDSDNIYAVIKGSAINHGGRANNLSAPNSKAQEMV
ITSAMKDAGLKPDDISYIEAHGTGTVLGDPVEIRGLDAAYSKDTERKGYCAIGSLKSNIG
HLESAAGVSGIIKVVLAMKHGKLPPTIHFNKLNPFIDIINSPFYINDKLKEWKCQGPKRA
GISSFGMGGSNAHIIVEEYPVNKMQEERKLRKYNVITISAKNKNGLKKLAASYKNMLLED
NTAEFQDVCYTTNTGRGHFEYRLAINADSVDKVITALDAFETESVKEKELFFYGENNNKN
IKVTYHFSGQVNLETCAETIEELYQSEEQYKTILDKFDSILCKKGINFLQLIKQKDLFKK
QVNEDEKIKGITGFLFEYSLGKMLEHAGLAPISMEYTDKGVYTVACLTGYMEVEKAIELI
LKGVTEEDDYFKEIKESLDGDSDQQADYKLYLGYKSTEQINEEKSLLPINSFINKDCNLF
TFIISKLYSLGVDLEWSGIYQQYSTRKAELPLYPFSRNSFWKQSSMIAPASAVKEVYEIS
LISGDYQHSIYNIKLNAVLEKLMNEHKVLNNRIMPGTGYIDIVMFVMQKFTGSVPAKIQN
VTVLNTITYEQFNSGEVIIECKKNSDEGLFTICKSNSETTGERQIECVTGRVSFEKQVSQ
NIDKNNFNLIDGNIIDSIDIYEAYKSIGMNYGKSFMCIDSIRINSKQFVSHLSLKEQSEL
GYFYVHQGMLDGALQSIIAASMNNGVDNSTAYLPFYYENILIYEKLNTSKYICHGEIKED
ISKAASNIKCDIDIYDTYGKKIISIEGFTVKKKQLTLQNGKNVNVSSEVMNYLNEVRWIN
VNLNNNDIKMDKSGKWLIFSDNNRFTNILKEKLAGYGQEAIIISEVKDIEQEISSIKDMH
SSIRGIIYSTAYDNAKAKINSIECFYREEGATLRNLFYLAKSLGSTNRRQKLEFITLTGD
AVYIEEKKAEINPKNASVWAFSKVMDIENESLNVRCIDFDCGQLNEEGNSESIAREICLG
ADKYVLYNGGKRYISEIYQLKSEVAQTPSKFLEQGVYVITGGLGEIALETSKYLAENYNA
KLILLSRTAFPDKKDWNSIIENQNENHKDYKRIKAIEALDSEVEVLQCDITNEAQLKDCI
DSIRRKYGKINGIFHMAGIIKDKLISLKTWDDMVEVLAPKVIGAELLDKVTENDNLDFFA
MYSSVAAITGNMGQSDYAAGNSYIDALAHRRRASGKTAVSLNWTLWEQIGMGVKFINAQK
SRGVKTIKNAAAMEAMEYSLTRENGQVIIADLSQYITSQKDNDGKDYKQEAEDYFINKIA
DFLCAALDYNKESIDITTSFVELGIDSILGVEIIRKIEDLLDTPLNPTFIYDYPNIERLS
NFLAANYLDEIIDKGLVACSASSVENERTFIDEIATETLITDTAEEEFEETDIAIIGMSY
RLPGTDEENDFLDFLTKGESAINEFPWDRALTKVQKQDNNKPLGGYLEDIYSFDPQFFNI
TPKEAELMDPQQRTMLKVVWEAVEVSGYSDKIQGSDTGVFIGVSTNEYQLLVGEHHSQVG
TGNALSITANRISYFFDLKGPSMAIDTACSSSLVSLDTACANIRQGNCDMAIAGGVSLIL
TTNTTKVFNEAGMLSADGRCKTFDSSANGYVRGEGCGVVVLKPMKKAKEDKDNILAVIKG
SSVNQDGHTNGLTAPNAISQELVIKKALKLSKVNAENITYIEAHGTGTPLGDPIEIRALT
SVFNSFTDRKSFCAIGSVKTNIGHLEAASGIASIIKVILALKYKVILPTLNFKKLNAHIP
LIDSPFYIADEVKPWKCENGKRIAGVSSFGFGGTNSHAVIQEAPSIARVSDASEKHCIFT
VSATNQLSLRNNIKRLCAYIKKNKEINLASISYTLTARRKHFSNRIVFIAQNRDEVIRKL
EYILSQENFKTDNEYGYSIIKSNYAVRSSKVWGQKLEENLTADERVSILKELEKAYLLDE
KIQWFKIFAEDERRVSELPPYCFNEDRYIAGEENSEKAEESLVKTENSDNSKTIKVYSYS
TEGLADKISSIFVEQLIEKLKFKADQIDIDSSLMDYGFDSIFAVSTLQVYEQKIGTQLDP
TLLFDFSSIRDFSKYLAEEYNEQFQTYFAGTEESEPVVEQYISPIINTTEDTLRSETTPL
KLINKNSSDIAIIGYSGRFPKCDSPEMLWNKLKEGFDGISQLPEERYVYGGAEKNDTLKN
VFSGYIGNVHMFDPLLFNISGKEAECMDPQQRLMLEVVWETLEHSGYNSQELSDRKTGVF
VGTSSKDYSVLISEGKSFSPYMGTGNAPSIIANRISHTFNLKGPSISVDTACSSSLVAIH
LACQSIYSGESNIAIAGGVNLLLDYDSQAIFEKAGMLSADHHCKTFDDSANGYVRAECAG
AIMLKPLEDALRDGDHIHAVIKATGVNQDGRSNGLTVPNAVSQTELLCDTWNKGGINPET
ISYIEAHGTATSLGDPIEIRGITEAFKKYTNKKSFCAVGSIKSNIGHAESAAGIAGIIKV
ILAMKHGYIPPSVNFKRASKKINFIESPVYVNAALNKWESCDGAPRRAGISSFGFGGTNS
HILLEEAPKISADVCKEPDSALSLLTLSGKNQSMLKKYLGDIYSHIKKNNDLNIYDLCYT
LSTGRQHMNNRLAVKCNSRDELLNKLESVIESDFSDNMQGVWKSENSDKKHQPVVFMYTG
QGSQYKGAGYTLYLNEPIFREALEKCEELLLPYIKYKLTDLLYSDKCSEELLNQTNIAQP
VIFSFGYALTCLWMEWGIRPDIVLGHSVGEYIAAVVAGVFSLQDGIKLIAERGRLMSEVA
AEGEMYAVFANLEVIKAYIKDYPSDKIRIAAINSPNNIVISGDKEIARQVIKKLSENNIN
SQKLAVSNAFHSPLMEPIVNEFRALASKIQYFKPVIPIVSNVSADIFKDKTFNPEYLVEH
LLNPVKFMDSIELLEEQGYKVFVEISGRQTLVNLCKNIFIDKKDKILLSSLQPSKNYLET
VTDVLGQLYALGSKINWCKIYANKKGRKIPLPAYPFNRKSYWFKELQDSHMSSKTGRTSS
MRGKKVQ
>F1TD54|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
MNLEEFFLALQAKEISPEDAKKELRKIKTVPEQSLSEESNQEIASIGEEKRFIDNKEAVA
IIGMSGRYPAAGNLEQYWVNLAKAKNSIQEVPKSRWDVNKYYDPRPSQKGKVYSKWIGLL
EDIECFDPLFFNISPTEAEVMDPQHRIFLEEGYKAFEDAGYSRQLLNSKKCGVYLGIMNA
EYGIMLWQNQASTNNITGNSYSIAAARIAYFLNLKGPAIAIDTACSSSLVATHLACQALL
SHDIDMALVGGVTLYLTQEPYIGMCAAGMLSPDGQCKTFDQNANGFVPGEGAGALVLKRL
KDAEADNDPIYGVIIGSGINQDGKTNGITAPSANSQAELEREIYNKNKIHPESISYVEMH
GTGTKLGDPIELEALSTVFMEKTTHKEYCGIGSVKSNIGHTSAASGIASVQKVLLCMKYG
KLVPTLNFQNPNEHFNFKESPFYINTELRPWKVSQGMPRRASVSSFGFSGTNAHIVIEEY
IPKLATAKAQIPVNENTPILFALSAKSEQQLRFHAKNMKEYIESHADLNLVDMAYTLQVG
REAMEYRLAFLADSRETLLKALKDFINNNSTTEVLTAQVKKSKDGVAAFKTDEDAEVLFQ
TLIQKRLYYRIAELWVKGLAFDWNKLYSGIKPNRISLPAYPFFRERYWIPQIKYEGGNKS
PILAEDSWPFNTEIVIHTKEWHAKAIDTKAPIQSGVVAVLGTPATRKLAFALFEDMEGLQ
VIQVIHDEIGSDEEILTDFYSSSAGESLYEQFKDKLKGRKILGVIDITAHDSAYEQSTTI
ESGKITFLQKLIEYDRNEGYRLLQATYKLHAFQLAAATIQGARTAGLYRMLGAEYKQIQA
MSMDSDCSVENHIILTQQIQTEFLNMDKVNPTECCYRKNERYEPYLAISQTNSVIQDKLG
IPEKYDEHDVVLITGGTRGIGASIAEHVVSQGIKNLVIMGREALPEPSEWNNILDGNGKL
EIEQKLKRMQSLINRGVRIRYYRTPLSDENGMKAMVQDIHLHLGHITGVFHCAGLTSRNP
AFFKKSIKDFEAVCEPKMKGLVILHRALEEEPLDFFILFSSISSIVPTLSTGQSDYAMAN
AYMDYFAMNQVGEEKHYFKSVQWPAWSGTGMAAGGVHTAAYKAAGLTSLEINDGLALLDM
VKRMPHIVSLPCMVVPGEFTPDHLLKTKIMPGMQKYGLELQRSSEQKPEASPAQQSRADL
RTCTMQWLKQVFCSELKLSANQLNDEKPFDEYGVESIIMAQLVQLLQEKVSKKIDPSLIL
EYSTITALTDYFLANHAEDLQKNLGHEKKCVKEDFRISVNQPKVISEPKKSEEDIAIVGI
SCRLPGSPTKEAYWELLTTGVSAIEPVPPQRWSSKNNRQDYGGWIENIDLFDPQFFNINE
NDAAIMDPQARIILEESMHAIYDAGYEHKQLSGQKVGVYIGGRYQPNTNVDAILRAPNPV
LGIGQNYLAANISRCFNFKGPSLVVDTACSSGITGMLLACDSLRERRIDMALIGAVSLLV
NPYAHDLFAARNILSRNGEFHIFDKRSNGEVLGEGAGVVMIKRLCDAIKDGNHIYGIIKA
IAVNNDGQTLGPGSPNINAQEQVMRDALTLSGKQLEDIGYIEVNGGGSAIVDSIEIKALS
NVYNLGNKALKPCGIGSVKPIIGHLLLTAGMAGFIRCVLSVYHKKIPPFLSTLDPFSSYD
FSSSRIEFNRKTIDWTVDYGKKRIAALNSFPDGGTNCHVILEEFVSDGNYQQKYFPRKAP
GMVKKRFPISLPELSSDMENTKHSRVAITNIWGEYYEKEV
>A0A379MZ53|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Roseomonas mucosa|TrEMBL
MPVLKNPRKNRAPKAQQKVVPVAIVGAACRFPGAADLDAFWRLMAEGRDAVSTLPEDRFS
QARFHHPRKGEPGRAYTFAAGHLGDIAGFDARAFGLSPREAAEADPQQRLLLEVAAEAIE
DSGLPASTLAGRPVGVWIGGSSTDYAELRLSDPSGADRYFMTGNALSILANRLTNVFDLR
GPAQTVDTACSSALVALHHALRALAHGDAEMALVGGVQLLLSPYAFMGFSRASMLSPTGR
CRAFDAAADGYVRAEGAGMVLLKPLDRALAEGDRVRAVLLASGVNSAGRTIGLSLPNGEA
QAALMERVMREAGVEPEQFGYFEAHGTGTQAGDPIETWAIGEAIAKRRRAPLPVGSVKTN
IGHTEPASGMAGLLKAMLVLERRSIPPSLHFSTPNPNIAFDGLNLRVPVAEEPLRLGSRP
ARRRGDPAPVVGVNSFGFGGTNASVVLATAPVTAALEEPASGEVPALPATPLPPLLLSAR
SPAALRLLAGRWQARLAETPDGDLPALLRGAARHRDLQPQRLALRGRTAVELAAALADWS
EGRDNPAATEGQAPAASDIPAGGLAFVFSGNGSQFPGMAREALAASPALRAGLEEADAAL
APLLGWSPAARLAAGVSEAEVAGTDIAQPLLFAIQAALLRALAGEGLRPALVIGHSVGEA
AAALAAGILDMDQAARLVVARSAAQHRTRGQGRMAALALPPEEAAPLLAEAGPGLEIAAR
NAPRAVTVAGPAGAIARLADLAKAHRASCVPLDLDYAFHSAAMEPVREALLGALGTMAPR
PGQIPFVSTVTGAPLPGEAADAEYWWRNLRAPVRFAEAMAAALGQGARLFLEIGPNPVLQ
SYLREGARAAGLTAGTLFSLSRRDRPEAFPGGDPVPAIADRATTRGADPRGGALFRGPAR
RDLPLTPFARERHWLGATAESHRLHDAPRDHRLLGERQDPEPRLWGREFDTLLEPWLDDH
RLGGEPVLPGAAMLEMALAAAALRFPEAPALEVATFQILRPLPLSDGETRQVRLRLADDG
VVTLESRLRLAETAWTLHARGRLGEANEAALPATAALALAAPDEMTGPEITALAARLGLD
YGPAFRPLVSVATEGGQALLRLALPGAAPPDEGFHLHPVRLDGALQGLIGLLAPQFPARA
DALPEGEALVPVRFERLVFRRGAAPADSAELRLASLGERSAEASLLLRDAAGQVVAFAQG
VTLQRLRLARGEEAPLRAFRLEDVPVADPSLPAPEPALDDALAAAMRADERLDLSESALL
LEGWAGVLAQRALSALPTIRSAPATPPATLAGGLWQALAEDGLAHHDGTAWRLLPQEELP
APEEIWQSVLADQPALAHDLAWLALAAERLPDSLAGHVPALPLAPPDLAGGQDRLAETAA
AAAAALAAAWPADRPLRVLDLGGAALTRHLLAALAETGRAVTLLVAGEGRPLPEARGHVA
PEALAWDPLSEQPAPVAADLVVGIGAALRARCGTALLSRLAPALAEGGTLLLAEPLPGRL
LDLALGQEPGWWSGRPLPDAAEWRAALAREAGWHHVRAEPLRAAPWPALLLLATRPAPVR
HPATGSVSARPASARLLLLADAGAAALRDALAGELAAALPDALRDGGWLEDAAALPARDL
RGADLLVLAAPGEADPATSLAATLAALARLAEAAQGTVRRFTLVIAGTPAQPVAEALRAF
ARGLANEMPDLAPRRILLDTALAPRAAAARLLPELLAPGAEPELLIGAAARRAPRLRPGG
AEPRPPAAPARLAVRQPGQLGSLGWEPSPVQHAPLAQGEIAVRIEAAGLNFRDLMWAQGL
LPEETLRDGFAGPGLGMEFAGVVEAAGPGTALSPGARVFGFAPRALASHAVTRAEAVAPM
PEGMGFAAAATAPVAFLTAIWSLEACARLQPGERVLVHGGAGAVGLAALQVARAAGAEVA
MTAGTEAKRAFLRAAGADLVLDSRDAGFADHLRRHWPDGVDVVLNSLAGEAMERSIALLR
PWGRFVELGKRDYAEDRRIALRPFRRNISYFGVDVDQLPAARPGEAQRLIESLRDRLSRG
ELIPLPRLTRRAEEVEDAFRLLQASAQIGKIVILPPRLQAEEKPGWTPPEGLVLVTGGTG
GFGLECAKWLAASGARRLALVSRRGPATPGIEAALVALGALGARASAHACDAADPQALAT
LLDTLRREGPVAGVVHAAAVFDDGALASLDAPRFAAVLGPKLRAALNLDRLTRRDPLELF
LLFSSATTPLGNPGQGNYVAANAGLEALARARRAEGLPALAVGWGPIADAGILARESGTA
ATLARRLGVEPMASREALDSLPALLSGDRPVVHLARLGWRRLGAALPVLREPAFTLVREA
GGTGAEVEDMRAHLATLPPEEARALLVRIGAEELGRILRLPPESLAADTPVARLGLDSLG
GLELRGALEQRLGLSVPLAGVTDDLTLGSLAARVADGLRGGGEEAQVAMLLEHFEPSHPP
EDLAAGGEAASGGHAAPPVPSRDIARGIPSHPSPGGPQPGAAGGQPLTTEGETAR
>A0A3N6CIA5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI91-18|TrEMBL
MTESAAASGIESWRYRVAWKGLSLPESVRLDGRWLLVVPEDLDADGTRVAHDVEQALTTH
GATVSRLTVDVTATDRADLAARLTTTAAEEQEPLVGILSLLGTDERQHPDHPGVDRATAA
TMLLAQACADLDADVARGVEPKLWVVTRGAVAVSPAERPSSAGAQVWGLGRCAALELPTR
WGGMVDLPRAARDTGRQGRQLVRVLSETSAEDQVALRASGAYGRRLLPASSPSASAPRAA
KGGYQPRGTVLVTGGTGSLGGHLARWLARNGAEHIILAGRRGEVAPGAAELSAEIKELGA
EVTVAACDVADRNALRDLLDALPAGQPLSAVFHAAGVPHSAPLAETDVAGLAAVVSGKVV
GARHLHDLTREKELDAFVLYASGAGVWGSGGQSAYGAANAALDALAEQRRAEGLTATSVS
WGLWDGGGMAGEQGEEFLTALGLRAMEPESAVAALGEALDRGDTCVSVVDVDWSRFAQSF
TAFRPSPLIADLPGVRTAPDGPAGGPSEGLSGGARPVGAADPGVLARLARATGDDRLEVL
LDLVRRHAAAVLGHPGPQHIEPDAGFRTLGFSSVTAVELANKLGAAVGTKIPATFAFDHP
NARAAAARLDVLLAVPSDAAAQEAEIRQALQNVPLARLRAAGLLDGLLELAGLGAESGGW
ADLPGGEPHRGAATPDEESALAEVDGLDAEALVDLVLNQSDS
>A0A8B4DI52|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus subsp. massiliense|TrEMBL
MLRREASALLAYVAEHPRIAPNRIAGMIFRTRVARRYRTLVTVENHDQLVAALRTVVAGT
EHPLVVRNSEPATARRHGFVFPGQGGQRPGMGRLFYDAFPSFRAEVERCADLFAKQFGRS
PLSYLLDDQLPPNDSATVVQPALFTQMAGLAALWRTVGVIPRAVVGHSQGEIAGAYVSGV
MSLDDAVTVVGTRAGIADKFPADDYAMAVIATDRDTCEELLARNSGWAELSVVNSPSMVG
ISGQRETVHQIVEHLTGDGVFARVIPVRYPAHTSMIASIGAQIRHALTENLHAGEFTVSE
IDCIGATLGTAISPEMPVDQYWFWNLRNAVRFDRAVATAAAAHVDTFVELAEHPTLQLAL
RENLAALGSERTARVVSTSHRNATDLAEFTANLAKIAVHDLDYNWDALRAEAPDRVSLPL
RDFPNVQNNDIPLWLSYRAGTSGVAVPKQPAVTPEAERRVDTSNDSRAYPRLLREAWTKV
TRRSMMPPRSYAFIDGTGDAGALVEALRDNAPNFGSSARIVTGTNESGIGDADTVVIVLP
SPALLDDREAAEAVARFFGNRTWWPGLSSTVTGCWLVTVGGEQAVADDRPAHPVHAAIAA
GFRCMGTEHPGIAFRHLDLTPDIAGPDKADNILAALQSAGESELALRADGMYAKRVIDID
QDGDESSRAVAPDHVVITGGTGKLGQEFCEHYARMGTRQITLISRSGETDAVTGRLDAIR
RSTGAKVRALPCDVTDTAAVTALADQLRDTPADLIIHAAVDYSDTPLAEVTADKFQDALR
AKVIGISNVLDTVPRTDSCRVMLCSSLAATIGGKGQLMYAAGNRMLDVLASTRRASGLDC
TSIQWGQWTVHLDLGDTGIAKLAAAGVHPMRPADALAVGMGRHHGNTLVGAFDLTRARAM
LGVFGYGPLLSELEDNSGPVAPAETIRPAPVVPENRSGHLVQLLAEVIGADHADSIDTAM
PMVAMGLDSLQALEFRRRVQAELDFELPVQDLLGGASVDHVIDALTAQSR
>G6FT28|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Fischerella thermalis JSC-11|TrEMBL
MSQFICFSVSPINLAHPGIAVATTRAGGIGILDREFCHDPKQASNNLDKLLALTNPGQSV
GIRLSATQVASSHALLKRLSHQPHWLILCGWNAKTLVETVASLPTGRSRKLLLEITDIEQ
AQALDNQIQNINIDGLIARGHESGGWVGEDSAFILLQKLLSVQSRPVYVQGGIGIHTAAA
CRAAGAAGVVLDDQLWLMPESPLPQEWQRHLSNLNGQEAMVLGERLNAGCRVLSRPGFQA
ITNLQQLADQIEVENDGSADGVQNWQQQAQPLIGWGEPGKLAWPMGQAVGLAATFRDRYP
TIGKLIQALLKQSQEQIKTAQQLRPLDANAPLAVSHGTQYPIVQGPMTRVSDTAEFANAV
SQAGGLPMLALALMRGSQVRSLLQKTQQLMGNRAWGIGMLGFVSHALREEQIQAVKEFKP
PFALIAGGRPDQAAQFEAEGIATYIHVPAPRLLKMFLEQGARRFVFEGRECGGHVGPLSS
FVLWESMIATLLADVPPGKESEIHVLFAGGIHDALSAAMIAAMAAPLVERGMRIGVLMGT
AYLFTQEAVACGAIVQKFQEQALACSRTINLETGPGHASRCVFTPFAQEFYATRRQMMAA
GSPPEEIKDTLEDLTLGRLRIASKGLQRTPDGQVQTVDEAQQLTNGMYMIGQVATLRDQV
CTVRELHQNVSEIGTKLLISAFVEQDGEQKVTTRPSDIAIIGIGTLLPQAQYPETFWNNI
LRKVDAITEIPAQRWDWRLYYNPDRNARDKVYSKWGGFLEDVPFDPLRFGIPPKSLKSIE
PVQLLALETVRRALEDAGYGSGNFDREHTSVILGAGGGIADLGQQYATRCEIPRMVGKTT
PEVWDRLPEWTEESFPGLLLNVIAGRVANRFDFGGHNFTVDAACASSLAALDLAVKELES
GRSNVAIAGGVDTVQSPFAYFCFSKTQALSPRGRSRTFDKTADGIAISEGIAVVVLKRLA
DAERDGDRIYGVIKAVASSSDGKALGMTAPLPAGQMRALRRAYKKAGFSPNTLGLYEAHG
TGTPAGDKAELETVISVLKEYQAHPKCCAIGSVKTSIGHTKSTAGIAGVIKAVLALHHKV
KPPHMNVDTPLDPIIDHESPVYLPKEAQPWLAHPDHPRRAGVSAFGFGGTNFHAVLEEYR
GNWQATAPGADAWPYELFVFRAENRAALAQEAKSLLRDLSNGAEPRLQDLAHSFAQRAQT
RQNQSACLAIVAESLSQLRVDLEIAIAQLEGRQSQTLPPHIQFGMADPQANQQVAFLFPG
QGSQYSGMARETGLYFNEIRGTFEFADRQLRQCFPKLLSQYVYPPSPYSEEEEKQNYKQL
MDTRIAQPAIGAVETGLMDLAARLELKPVMVGGHSFGEYAALHAAGVLSREDFFNLAATR
GRVMAEACATSVGAMAAVQTTREDLLLRLQNFEGVVIANQNAPRQSVISGDKQVVQQVVD
SLNAAGITARMLPVSGAFHSALVASAQAALAAPISTVTMHSPRIPVYANSTGRPYGSNIN
DIRSQLSKQLLNPVEFLGQINAMYADGARIFVELGPKHVLTNLVGQILAQKEHTAVSLDG
QGGGLRGLLMALGTLFVRGVHIKLTALFDGRDVQNLNLAKLVELTRKPALPPTAWLINGG
SARPQNQPAGYTGKLPPLNQETAALIAPLPELSLGLKPQATPTQPVPIQEQPTPKPQPHT
HLVSKKPEIPMNQPATSSTPANGKSLNGNSSPLPVPANPPQQAMGAGILQAYQAYQETMR
KFLAVQEQVMSQLLATTNSVPTLTPATTPLPPRRQPENHLPPAPQPVVVQPKNGSAPTLT
PNNKQEQIPVAPQPLIPQPVSAPPVQEMVVKQVPAPPATTQFLPDRASLTQTLLGLVSER
TGYPADMLGLDQDMEAELGIDSIKRVEILGAFNQALPASLADSVRQQMEQLTRVKSLNGI
VDKILENLQPTAAATVTNTVTAANISSASVGESLNQTELTQTLLQLVSDRTGYPTDMLGL
DQDLEAELGIDSIKRVEILGALQKSLPQSLATSVQARMESLTRVKSLNSIVEQVLAISAQ
ENGLGKSPAQLQVSHAT
>E8WKL0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Geobacter sp. (strain M18)|TrEMBL
MLKTDDLKPAISSNGTRLAIIGIGCLFPQAADKNAYWANIVDGVDAITEVPPTHWPIDAY
YDEDQKSPDRTYGRRGGFLSPVDFNPMEFNIPPNVLEAIDTSQLLGLVAAGQALKDAGYG
PDRSFDKSSVSVILGVTGTLELVIPLGARLGHPVWRSALKDAGVDEETARDVVERISDSY
VPWQENSFPGLLGNVVAGRISKQYDLGGTNCVVDAACASSFSALHLASMELNSGKSDIVV
TGGIDTFNDIFMYMCFSKTPALSPSGNAKPFDVSADGTILGEGLGIVVLKRLADAERDGD
RIYAVIRGVGSSSDGKGDAIYAPSASGQKKALLNAYKNAGVTPETIGMLEAHGTGTKVGD
AVEVSALREVYGKAENPWCALGSVKSQIGHTKAAAGSAGLIKAALALHHKVIPPTIKVQT
PQKEVVADHSPFYLSTRKRPWFPRPDAPRRAGVSAFGFGGSNFHVVLEEYQPKKQSADWD
GNTQVLAFSGADASALAAKLDSVPAGAAWHAIRDLALASRASFDAKAACRLALVAERNKT
NLASLVKNARAMLDKNAKSAWQTPDGAYFACGGAPGKLGMLFPGQGSQYTGMLNDLACRF
PQVLDSVTAANQGFGCTGGRMLSDLIYPPSAFDEETSAKQEEALRATQAAQPAIGAASLG
ALRVLQAFGLNPDAVAGHSYGELTALCAAGRLNEDALHELSRLRGKLMGAGDGDKGSMLA
VSAPLARISEVVAAEKLDLVIANKNAPAQAVLSGASAEIKRAVPIFKALGLTCKELPVAA
AFHSALVADAAKPFLAALEKIDMPQAGIPVYANTTAAVYPSDVAAAKAQLAAQLAKPVEF
VAEIEAMYAAGITNFVEVGPGNRLTGLVQAILGDRPHLAFAVDASSGKRAGVADLARVLA
QLAVLGYGVNLALWDEGHRPAPAPTGKKPALTIPICGANYVKAKPKKPPVLPKPAVAAPV
QTVAAPVQPQPAAQVQAAAATVQPQTGYQSAAPANPAQGTCQPQAVQPASQGALTESLRL
AREGMAVLQKMQEDTALLHRRFLEGQEVAAKTFQALLAQQQHLIMGAPVGQAAPVAFAPV
APAPAAPVQAQAYVAPTPVAPPAPVQAAPAPAMPAAAPVVSAAPAAPAAPVAPAASSNTD
AARITQTLLNVISEKTGYPIEMLELDMGMDSDLGIDSIKRVEILSTLQDRLPGTPVIGPE
HLGTLRTLGDIAGHLAAGAASAVAAPPVAAAAASVASVAVPATGAATAQVTETLLAVVSE
KTGYPVEMLELDMGMDSDLGIDSIKRVEILSTLQERLPGSPAIGPEHLGTLRTLGDIAGH
LAAGSVSAAAFAPAAAAPAAAVAVPAAGVEAAQVTETLLAVVSEKTGYPVEMLELDMGMD
SDLGIDSIKRVEILSTLQERLPGTPAIGPEHLGTLRTLGDIAGHLAAGAVSAPAAVSVAV
AHQTAPATPAGDITAVLLEVVSEKTGYPVEMLELEMGMDSDLGIDSIKRVEILSTLQERL
PGTPAIGPEHLGTLRTLGDIAGHLGSGDVAPAAVSEPAAPAPGTPVPAAATSAAAVDPAA
VTQALLEVVSDKTGYPVEMLELTMGMDSDLGIDSIKRVEILSTLQERLPACPAIGPEHLG
TLRTLGDIAHFLAGPAKQAPSAIEAVALPATPADAAPAAPVAEPVQAAPQAIQRSSVVPV
LLGENDDADAITLANDGEIWVTDDGSAFAAELSGILLEHGCSVRKVDASQARQIAPAGKL
SGLVICAPVAGTDDQFLEDAFQLLKNASAALLESGRSEGAVCITVSRLDGAFGFGSGKSL
KDPLSGGLAGLAKTAAFEWPEVACKAIDLGEFPHPAAAAGAVAIEMLRSGPVEIGLTPEG
RFALQSAVLPTAAAPVVPAIAKGDVVVITGGGRGVTAVSALALAKEYHPFLVLLGRSSEP
QEEPAWLLGLTEEADIKRAIMQNAVGKLHPREIEERYRSVEAGRELTATLESIAATGAEA
IYRSVDIRDQSAMELLLGEVRRAHGPIRGVVHGAGVLADRLIVDKTPEQFEQVYSTKVHG
LRALLHATRNDDLKFIALFSSSTGRFGRVGQVDYAVANEVLNKTAQAEARRRSGCRCVSI
NWGPWDGGMVTPALKKVFASEGIGVIGLAEGGDFLAREISAAEAPVEIVAIAQLPEQVSA
AAPATSKHLSLSEAFSLTLTVPEYPFLRSHVLDGKAVLPMAVIVEWLAHGALHGNPGFRF
HGFNDLRICKGVVFEDNTPFTLNVMAGRAEKRESFWLVPVELSSPGVNGKTILHARAEIV
LATRHPEGIRSITEIPNTPYAPHDGVIYNSERLFHGPDLHGIEHVDGCSAKGISASVKGA
PAPAKWIRRPLRSAWLTDPLVLDSAFQMMILWSFERFGAGSLPCFAGRYRQFQESFPREG
VQVVIRVISETRHGASADMEFLDRNSGKLVARLEGYECVIDPSLKQAFQRNKLRTVTVVG
AA
>A0A221W529|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinoalloteichus hoggarensis|TrEMBL
MEVLPEGGAMVAVAASEDEVRPLLSDAVSLAAVNGPRAVVLSGVESAIGSLEQHFVVLGR
KTRRLSVSHAFHSSLMDPMLDEFAEVVGGVRFESPRLPVISLVSGEVAGAEITTPEYWVR
HVRETVRFADGVTTLRGTGVTRFLELGPRAVLTPMITDLVADATAVAALRRDRPEPAALS
AALAVLYTTGVDLDWAALLPDARRVDLPTYAFRRQRFWPEPGADSADVAAAGLSAVEHPL
LGARVSVAGTDGLVLTGRISTRTHPWLADHVVHGTTIVPGTALVELAVHAGDHVGAPHLA
ELTLHTPLTLTRHDTQVQIVVGAPAENGERPLHVYSRPDDDASWTTHAGGVLLAEAYRPA
AADLTAWPPADAAALPFDGAALYSRLAAGGLAYGPAFRGLRAVWRRGDDVYAEVELPESE
RDRAAAFGLHPALLDAALHAVSFADLGAGDDRGLVPFAFSGVSLHATGADTLRVRLSPRG
PDSLALTVADGTGAPVAAVESLVLRPMVADRLGMSTDALYRVDWRPRDVESRAGIGAEHW
AVLGETALAASLADHLPEAPRHTTLDEIAAADVVVAALSTGRDVETADVHTAVRAALALL
RSWLAAERFAESRLILVTGMAAGPDTACPAGAAVWGLVRSAQSEHPGRIMLVDVDEHPAS
AAALPALAAAGEDQAVLRGGTPVVPRLGRLPNPGEPGGPLRPPPVEHWRLDAPERGSVDN
LTLVECPEAGAPLTAGQVRIEVRAAGVNFRDVLGALGMYPGPPVPLGIEASGIVREVAPD
VTALRPGDRVMGIVGGGFGPTTLADHRLCARIPDSWTFAEAASVPLVFLTAYYALVDLGR
VRPGETVLIHAAAGGVGMAATQLARHLGAEVFGTASAAKHDTLRALGFTEDHLASSRDLR
FEDRFRAVTDGRGVDVVLNSLAGEYVDASQRLLVPGGRFLELGKTDVREPSAGYRAFDLI
EAGPDRIQEMFAALLALFADGTLQPLPITAWDVRDARTAFRRLSQAGLVGKAVLTVPTAW
RTDGTVLVTGGTGALGAQLARHLARAGFRHLLLISRRGATPEAEELIRELADLGAETEVL
ACDVTNRAALTAVLAGVPADRPLTAVVHAAGVLADGLVDTLDADGLDAVLRPKADAALAL
DELTRGLDLAGFVLFSSLSATVGAPGQANYAAANALLDAVAIRRAAAGLPAHSLAWGPWV
ADGGMTSTVGAADRRRLAAAGLVPFTEDDGWPLFDLAVAAAAPAVVPVRFDLRALRARAE
ALSPILSGLAPTRRRQAAAGAANAGTLLDRLAGATDAERRRTLLDLVRAQVAGVLGHPSP
ESVDPDRAFTDLGFDSLTAVELRNLLASATGLRLPATLTFDYPTPSALVAQLDADLGGAA
AVPTPATSTRSADPAEPIAIVAMSCRFPGGVASPEDLWRLVAEGTDAIGDFPTDRGWDLA
GMADSGQQRAGVSYVHEGGFVDGVGDFDPRFFGISPREALAMDPQQRLLLEASWEVLERA
GVVPASLRGTPTGVFIGAASSGYGTGLAEMSEDLTGHLLTGNAGSVSSGRIAYVLGLEGP
SMTVDTACSSSLVALHLASRSLAAGECSLALVGGVAVLATAGMFLEFSRQRGLAPDGRCK
AFAEGADGTGWSEGVGVLLVERLSDARRLGHPVLAVVRGSAVNSDGASNGLTAPNGPSQQ
RVIRGALADAGLAASEVDAVEAHGTGTVLGDPIEAQALLATYGRDRPAGRPLWLGSLKSN
IGHAQAAAGVAGVIKMVEAMRHGVLPKTLHVDAPTSQVDWEAGDIRLLTEATPWDGGDRP
RRAGVSSFGISGTNAHVLLEEAPADPDPHADADAVPVASPPAPAVVPWLLSARSPQALAE
QARRLSSFLTAEPAREPADVGWSLANSRTAFEHRAVVIGEGRDELLAGLTTTEPTAAAGA
VGRLVLVFPGQGSQWVGMGRELLACSPVFAARFGECVDALGEWVDFAPLAALGDEVLLSR
VDVVQPLLFAVLVSLAAVWESFGVVPDAVVGHSQGEIAAAVVAGGLSLADGARVVCLRSR
LIAETLAGHGGMLSVALSEADVRRRLSGFEGVSVAAVNGPSSVVVSGDAVPLAEFAAAGE
ADGVRVRWIPVDYASHSAQVERIEADLRTALADLAPRSSEVGFFSTVTGDWLDTAHLDGA
YWYRSLRQTVRFHPAITALADQGHTAFVESSPHPVLVMPIQEALDAHDVLVVGTLRRDDG
GPRRLYDSVGQVWARGHAVDWTPAFGDHARRVPLPTYPFQRSHYWPANPRPAGDAAALGL
DVAAHPLLGAAADLADGGRTILTGTLSTARQPWLRWHSVAGTVLFPGAGFLELALHAADH
VGCRRVDELVLAAPLTLPDDGVVQIQVVIADAEADGRRAVSVHSRAVGAADPDWTRHATG
LLSPAAGPAESLRAWPPEGTVPIELGAEENGVLAAWRADEEIFADVALPADLHDEAARFT
LHPVLLTAALDAINLLGLDGALADGWMPFTWAGVSASAAGATAARVRLTRTAADTVALTL
ADGAGAPLATAESLVLRPPPAAPDAGGPSLLRMTWPVLPVDAAEQDGRWAVVGGDALDLV
ASLRAAGLPAESYLDLAALGAAAGRGAAAPDVVLVSAVTGADGDAAAVRADAADALRLVQ
DWLAQDHLHDSRLVLCTRGAVAVDAQDRITDLGAAAVWGLLRTAQTENPDRFLLVDLDER
EKSAAALPALLAAGEPQAAMRDGAVHVPRLERTASTPAMPPIALDGGTVLLTGATGTLGR
LFARHLVTRHGVRDLLLLSRRGAEADGAADLLAELISLGARPDLVACDAADRAALADVLA
AVPADRPLTAVVHAAGVLDDGVLGSLDEERMDRVLRPKVDAALNLHELIGDTPVAVVLFS
SVVGTFGWPGQGNYAAANAFLDALAAHRHGLGLPAHSLAWGLWAADDDLGGAGRSRMSRG
GLLPLSEAEGLALFDAALASREPVLVTAPLDTAALRSGAELPRMFAGLGRPGRRRAAAKG
TDSGALRRELASLAEPERRDSLTDLVRTTAATILGFTDGESLAADEDLLAAGFDSLTAME
LRNRLGTATGLRMAASVVFDHRTPAALARVLAEELAAAPETTPGSRTDPADSLRHLFRDA
CAANRLKEGLDLLAAAATLRPSFRDSVGYGSPLTPVQLARGDARPPLVCFSSYAAMGGIH
QYARLAAASRGVRDLYGIPTPGFLADEPLPETREALFDLYAEAVLAAAGDEPVILLGSSS
GGLFAHATASALEAAGRSPAAVVLLDSYVPRTVTGNAFWQQMTQGMFDRENLFGELDTTR
LSAMSWYFRIFADFEPGELDAPVLFVRPADAVRIGPEQREPEGEWRSTWDTAHTSVEVPG
DHYTMVESHAETTAAAVEAWIAETL
>A0A221W4M5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinoalloteichus hoggarensis|TrEMBL
MSNEAKLREYLKRVTAELHDTSERLYQLEEAAGEPIAIVGMACRFPGGIESPEDLWDVLA
AGGDVISGFPADRGWDVESRYAPGSDRSGTVHAREGGFLYDVADFDAEFFGISPREALAM
DPQQRLLLEASWEVVERAGIDAESLRGSATGVFVGLMHHDYAARLNGLPEDLEGYVGNGN
AGSVASGRVAYTLGLEGPAVTVDTACSSSLVALHLATQAVRAGECSMAIAGGVSVMSTPD
VFAEFSRQGGLAPDGRCKPFAGRSDGAGFSEGVGLVLVERLSDARRRGHSVLAVVRGSAI
NQDGASNGLTAPNGPAQQRVIRQALTSAGVTAAEVDVVEAHGTGTRLGDPIEAQAIIATY
GQDRPRPLLLGSVKSNLGHTQAAAGIAGVLKMVLGMRHGTVPRTLHVDVPTPHVDWSAGT
VELASEAVTWESSGARRAGVSSFGISGTNAHVILEEAPAPADPAADAEASSPADPENATG
GPAETPSSDKAISWLISAKSAAALRAQAGRLSAHVTARPDLRAADVAYSLATTRSTFEHR
AVAVGRDRAELLAGLDALRQGSPAPGVIAGVADVEGRTVFVFPGQGAQWPGMGVALLDTA
PVFRAAIAECERALAPLVDWSLTDVLRGAPGAPGYERIDVVQPALFAVMISLARLWRDRG
VHPAAVVGHSQGEIAAAYVAGALSLDDAMKVVVLRSRLFARRLVGNGAVASVAMSEADLR
RRLARWDGRLEVSGMNGPRSSAVAGAVDALEELVAELVAEGVRARIVPATVASHCAQVDP
LRDTLLELLDGITPRSGDIPFYSTVTGGELDTAELTPEYWYRNARLPIDFVGALRALFAT
GHQTFIEASAHPVLVAGVQETAQGADTPVVTVGTLRRDDGGESRLLVSLAEAHVRGVPVD
WPVRDGARKVELPTYAFARERFWLDVTSEPATGGEAVDSEFWAAVEAGDLPALSAALDVA
EGGLSDIVPALAAWRRRDQDRRAAHEWRYDVGWSPVAANGSETLDGRWLLLTGPAGEPTA
AALAERGADVTVLRVDVAAADRVALVEQLRAAAGPDLTGIVSLLAQDDGPHPVLADVSRG
LAASVALVQALGDLATDAPLWWVTGGAVAVDVAADGSPSSPTQAGAWGLGRVVALEHPRR
WGGLIDLPPQVDDRGITRLIQSLTRADGEDQLAVRAAGVFARRLRHAGRPASRRAWRPDG
TVLVTGGTGGVGAHVARWLIGAGAEHVVLTSRRGDQAPGASDLRAELEGIGGRITIAACD
VADRDKVAALLAEHPVSAVFHTAGVGDTASIDDITPDHLAELLRAKVTGARNLDELTRNR
ELSAFVLFSSGAGIWGGSGQGAYAAANAQLDGLAECRRAQGRPTTSVAWGFWGGGAGMAG
GEAGDLLSRWGLRPLAPELAVAALHAALDGDETTVTVADIDWARFAPQFTVARPSPLLAD
LPEPRAAETRADAAPSGLAATLAALGTAERRAAVRDLVLAQTAAVLGHRSADAVSPSRAF
KELGFDSLTAVELRNQLTSAIGVSLPTTVVFDHPNATALADHVVTVLFGGAEPERPVETT
AAAADDPVVIVGMTCRFPGDVDSPDDLWRLLLAEADVMSEFPTDRGWDLARLHDPDPDRP
GTTVTRRGGFLRDVAHFDAAFFGISPREATGMDPQQRQLLETSWELFERAGLDPATLRGS
DTGVFIGNNGQDYTVGIRDIPEEVAGHLLIGNAGSVVSGRVAYAFGLEGPAITVDTACSS
SLVAMHHAIRALRSGDCSLAITGGVTAMFTPRAFVEFSKQGGLAPDGRCKSFAADADGTV
WSEGTALLLLERLSDARRRGHTVLAVVRGSALNQDGASNGLSAPSGPAQQRVIRRALADA
GLSAADVDVVEAHGTGTRLGDPIEASALLAAYGQDRPRPLLLGSVKSNLGHTQAPGGVAS
VIKMVLAMRHGIVPKTLHVEEPTPHVDWSSGAVELATEAVRWPDSGRPRRAGVSSFGVSG
TNAHVVLEAAPVAERSEDPVESTSGTAVPWVLSARSAPALRAQAVRLADFVRDRPALRPV
DVGASLASRALLDHRVLISGSRLDDFLPGLADVVSGVLPVGGRPADSGVVLVFPGQGSQW
VGMAVGLAAVSPVFAARLGECGEALSEFVDWSLPDVLSDEAALSRVDVVQPVLFAVMVSL
AELWRSVGVVPAAVVGHSQGEIAAAVVSGGLSLRDGARIVVSRSRLIAGLGGGGGMVSVG
LPAAEVVDLLPAGVSLAAVNGPASVVVSGSEQSLAELVADCESRNVRARWIPVDYASHSV
LMDALRDELLDVLAGIEPRSSTVPFYSSVTGAAKDTASLDARYWFDNLRETVRFDRAVES
LLSDGLGVFVESSAHPVLTYGIGEVVEEHGAENVLVVGTLRRDDGGLDRFLASAGELFAH
GIDLDLTPFLTGGRLVELPTYAFQHERYWLDTRAEAPDVTSAGLDASRHPLLHAVVPLAD
SDGIVLTGQISVEEQPWLGDHAVAGTVLLPGTAFVELAVRAGDEVGAGVVDELTLHAPLT
LPDRGGVRLQVTVGEPDAAAIRAVAVHSRAAGARDWVCHATGHLRPMSAETGPDLRQWPP
ADAEHVDVSEFYDGLAATGYEYGPMFRGLRRAWRHDDELFAEVELPSGADGPARRFGVHP
ALLDAALHVAGLRPRATTEILLPFTWSGVTLFAGGASALRVRLRATGENELSLDVADPTG
TPVAAVASVRLRTVDVGRLAETTRHDGLFRLDWRPVPIDDDARCDRWAVLGGAEAKPLAA
LAGVTAHVDLAAWRGSVPASEPTPDTIVLSCLPAESADSPPPPVAARAAVLRVLAVLQEW
SADERWADTRLVVVTRGAVEHGADLAGAAVWGLVRSAQTEHPDRIVLVDLDDDAEAAALL
PAALTSDEPQLNVRAGRVLAARLIAEPPDRTGPAAPDIAESTPWDTDGTTLITGGTGTLG
AAVARHLVVEHGVRSLLLTSRRGSAAPGAAALSDELTGLGASVEVAACDVADRAELAALL
AEHPVAAVVHAAGVLDDGVLAALTPDRVHTVFAPKVDAAWHLHELVGEVSAFVSFSSASG
VFGAAGQANYAAANTFLDALAQHRRARGLPAQSLAWGHWAPPSELTGGLSDADRSRLARG
GVLPMSVREGLALLDAAIGVGRPTLVTARLDTHAMSEPAPSLVRELVPAVRRRTAAGRGA
ANGVPIGQRLAGLTPEERAQTLIRLVRTTAAAVLGHRSTETVPADTAFKDLGFDSLTAVE
LRNRMNRETGLRLPATLVFDHPTPAALAAHLRDLLRPDDVGARPDPEEDEITTILAAIPP
ARLRQAGLLDVLRQLAAGEDRAVEPLGSIDELDTEELLKMAQFGGDA
>K9PUU3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Leptolyngbya sp. PCC 7376|TrEMBL
MFGQFTSFVDLLQYRAESQPDKTIFTFLADGEAETDSLTYGDLHTRARAIAAYLQTHHAR
GERALLLYPPGLEFISAFLGCLYAGVIAVPAYPPRPNRSFGRLYSIIQDAQAQFALTTAE
LRGKIANRFEELENSAFQCLSTDNLSLDLAAAWKNPNVGLDDLAFLQYTSGSTGNPKGVM
VAHSNLLHNSHIIQTGFKNSQDVRAVSWLPPYHDMGLIGGILQPIYVGIFQVLMPPVSFL
QRPFRWLKAISKYKATTSGAPNFAYDLCVSQITQEQKSTLELESWQLAFSGAEPIRSATL
DNFSQHFAEVGFDKKAFYPCYGMAETTLMVSGTEPQALPREITVSKQAIEENQVREAIAD
EPTVTLVGSGQIIGDLAVRIVNPETLARCTDSIIGEVWVNGESVAKGYWQKNELTERTFQ
AQVDGETGFLRTGDLGFQRDGELYITGRLKDLLIIRGRNHYPQDIELTVEKAHPAIRQGA
GAAISVEVDGDEQLVIVQEVERKFVRHLNVEEVSQAIRGAIATEHQLQPYAICFIKTGSI
PKTSSGKIRRHACKLGFLDESLSVVGQWVQGLETRQSQPVTSEQKAPSHTWAAVGKGDRQ
QQELEAWLIDNIAQRLGVNSNKINVLEPFASYGLDSVQAVQVTADLEDRLERKLEPTLAY
DYPSIRALAAFLITGETATQTFAITPEKKLQNSEIAVIGLSCRFPQANNPEAFWKLLAQG
KDGIRQLGDRWGSDEWGGFLDEIDQFEPSFFGISPREAEQMDPQQRLLLEVSWEALERAG
IPANKLANSPTGVFVGISNSDYAQLQVREKNPINAYMGTGNAHSVAANRLSYFLDLRGPS
LSVDTACSSSLVAVHLACQSLINGECKQAIAAGVNLILTPDVTQTFSQAGMMSGAGRCKT
FDESADGYVRGEGCGAVILKPLADAERDGDSVLAVIHGSAINQDGRSNGLTAPNGLAQQA
VIQQAIARAGMSAADLDYVEAHGTGTPLGDPIEINSLKSVLKNDGQMREKPCVVGSVKTN
IGHLEAAAGIAGLIKIVLSLQHGKIPRHLHFQQLNSRIDLEQTLTIPAVAQLWIKLNQPR
FAGVSSFGFGGTNAHIIVGDRPTTTPQQSQAKKRPWHVLTLSAKNQVALKAVQGNYAKYL
TTQSDLDLQKLCLTANTGRSHFNQRRAIIFQDQADLQSQLATSVSSPPAITPQKIAFLFT
GQGSQYVGMGQQLYETQPLFKSVLDECDRLWQSFSSDAPTLIDLLYGGHDPQIVNQTIYT
QPLLFAVEYAIAQLWLSWGIAPDFCMGHSVGEYVAACLAGVFSLEDGMKLITARGKLMQN
LPSNGGMAAVFADKTAITPYLSKNLTVGAENGSHLVLSGQTLCLEQSLSKLQRQGIKTKA
LKVSHAFHSPLMAPMLGAFRQVAEQIQFHEPRLPLISNVTGQEIGSAIATADYWVSHVSE
PVKFVQSMQTIAAAGVNVFLEIGAKPVLLSMGRHCLPDVEALWLPSLRPQNDDWQEMFTS
LGKLYEQGLNINWQAVEADYTQQKLTDLPTYPFQRKRYWFSEKSWTNSETIEADFSEWFY
EVQWHQVELPQASEQKEGLWLILGDHHSQTLEIAQQFPQSQIVSLGDEFQQHSDHWEVHP
DQFDQLFTSLANTKLAGIIHGWAIAAEEQNLDHSQWLTCYTTLQLIQSLQRQQRQIPCWL
LTRNSQAVLENDKVEGFTQNSLWGMGKTIALEHPELWGGIIDLDAAIPNLTKLCNQTKIQ
HLACRNGSIYCSQLVPQTVTKTKISAIVPQAVYLITGGLGSIGRRLAQWLDEQGATKVLL
LTRRSLATDDSRLADLPKSAIAYTCDIADDHEVQNLFQRYPNISGIFHAAGVLEDGFLAT
QTWKNFEKVFAAKVQGTWNLHHHSLTNPLDFFVTFSSVASIVGSPGQGNYAAANGFMDAI
ARYRQGQGLPALNINWGPWATDGMATALRNQGMAFLAPEQGLHILETVLAQQTNVGVFKP
DWQQLSRQFPAIANSYYFRAVMGETEEVSTQNDIFERLQTLPTTEQQQQLTDYLRESIAR
ILKLDSTQIQPSDNLLDLGMDSLMVMEAIAHLKQDLRLMLYPREIYERPKLEVLAKYLGD
EFQKAHNPDYQQKTVSIPTQLPSQTNKTWQIPAQKNEKPIAFILSSPRSGSTLLRVMLAG
HPELYSPPELHLLPFETMGDRQEELGLSHLGEGLQRAIMDLDGLTAEESQQTINQWLTEN
RSIGDIYSELQTKATGRLLIDKSPSYGSDRQTLEHSEILFENAKYIHLVRHPYAMIESFS
RLRMDKLLGDTSANPFGLAESIWTKSNQNILHLGQTLSPDKYLQVVYEDLVKNPRVVLTQ
ICKFLGVDFDESLLNPYSGDRLTDGLHQQSMGVGDPNFLKHKNIDPALADKWRNVQLPQP
LNPTTIRLAQTFNYDLPNEDLTVSEVPTMTERSVTVRGLNYCLCEWGDRTKPLILMLHGI
LEQGASWQLIAPQLAAQGYWVVAPDLRGHGKSDHAQSYSMLDFLADVDTLAKELTDQSFT
LVGHSMGSIIGAMYAGIRRDQVKHLCLVETIVPNDIDDAETANHLVTHLDYLATPQEHPT
FPDVAIAARRLRQVTPALSEELSLKLVERSTEQTETGYQWRWDAFLRTRAGIEFNGISRR
RYLALLENIQAKITLIYGDQSEFNRSEDLAATQAAMPNAQRLTVNGGHNLHFENPEAIAR
ILMECLTF
>W6W133|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Rhizobium sp. (strain CF080)|TrEMBL
MLEGSNQVCASDIAIVGMALRVPGARNVAEFWQNLRDGVESVRTFSPEDLIAEGEDPERL
HHPNYVPRGADLPDMEMFDAEFFGLNPKEAAIMDPQHRHFLECAWEAMEDAGRTPNNQPG
PVGIFAGCGMGSYFYFNVCSNRNLVDQVGMFLLRHTGNDKDFLATRASFTFDLRGPSVNV
QTACSTSLVAVHYACQSLISGECDMALAGGVTIEFPHRRGYTFQEGEILSPDGHCRPFDH
RAAGTIFGSGVGVVVLRRLSDALRDGDVIHAVIKGTAVNNDGSSKAGYLAPSVSGQAEAV
LEAQGLAGVDADTIQYVECHGTGTFLGDPIEIEALTAAFRQSTDRTGFCHVGSVKSNIGH
LDTAAGVVGLIKATLAVNEGEIPPTLGFERPNPSIDFERSPFRVNNKLVKWPHAPGPRRA
AVNSLGVGGTNAHAIIEQAPTRYVPDATEGDAQTGADSDPMLLFLSARQRKTIDQAAERL
GLAMSAQPGLSLDDVSYTLQHGRKHFDHRMVLAVRSREDAVTALANPGSRGFVHQHVPNN
AGAIFLFPGGGAQYVGMAKRLYEEDRTFRRIVEEGLSHLPVDAAKEIRATWLDENSAAAA
KTFLRPSLQLPAILITEVGLARLWMDWGVKPKALIGHSMGENTAACIAGVMSFRDAVNLV
HLRGKLFETIRPSGMMSVPLDHDKLSELLPTSLDIASVNAPSLCVVSGLNEDLDLFREFL
ARQGIDATRVPINIAAHSRLVTPILKAFEAFLRDITLRAPAIPILSNRTGLPLSAEEATD
PMYWVGHLRSTVYFANGMAALSTEPGRIYIEVGPGRVLSSLTKAQGSIPANQVINSLPHP
DETGDDRLYFLSAVGRAWATGLDVDIDRLWQGRSPRRVRLPAYPFQHKRFFIDLAGANEK
GKNAEPVLSKEPDIARWGYRPSWKQTLADYEIGGEKEAQSWLFFLDETGAGQKLVDALRN
VGHRVVTVSLGDAFIRRSAEDYMLCPELGRAGYDALVAGLVGDGGLPSRIVHMWLLTQAE
TFRPGSNFFHRNQECGFDSMLHLAQALGDAASVPEMHFTVISNGMQQVSGEPLPYPEKAT
VLGPGLVLPKEMAGATVRVIDIDLPPEAERHGKRFALTRVTGRSEKKNAAEPAALIEQLW
EDLHATPGSEIVAYRKGRRWSQVHQRMPLKDVSPEQAKLRQGGVYFFSGGLSDVALALAD
ELAGQFRARIVLVGRLVLPPRAEWAFYDRTHGHDGVRRAISAIRRLEDRGAEVLYLIGDV
GNPEQMSRAVETSLSRFGEINGVLHAAGTVDDGLIQTKTRDSIDRVLTPKVLGTTVLDAA
FETVALDFFLMFSSTSTDVVRAGQVDYVAANAYLNAFAQSRSHRTDRATVALHWGVWNGV
GLAARALGNSGDDDWITPVAGPAVGPFFQNWKEDETGLPWLEALVSPETEWMLDEHRLLS
GQAVMPGTGYLELITQASREYGLPFEAEVADLVFLRPLVFNDGETKAVRIRLEPVAEHFR
VVVLAGPADGEDALFVKHAEAVLKPQPQRRRETVDIAATASACDETRVAGGGSALRAVQE
KHIRFGPRWAVLRSMAIGNGKAIAELKLDPSFADDLAKGVLLHPGLLDIATGFAMELAKD
YDAETSLWAPATYGRVVLHKPLPAEVVSIVRLADSSDFGEGYAAFDVTITDPYGNVVFEA
EKFVMRRLENDLALGVASQADAPAAAKAKQAALSPAMLKLGTQVRNGILPAEGFSALQRA
LATSEPQPIISSIDLETLREWIAASAETATPSGDNFERPDLENEFVEPRNPVEETLAGYW
RELLGIAKVGIHDSFFDMGGHSLIAVRLFRMIKKQYALDLPISTLFEAPTIAQCAERIAA
ELPDGGEAAGSETKANAPTTTAKPVHLVLMNPGKDAKAVPLFICAGMFGNILNLRHLAMT
MGADRPVYGLQARGLYGDHEPHATFEEMALDYIAEIRSVQPNGPYLLAGYSGGGITAYEM
ARQLQEAGEEVSHVVMLDTPLPRQPGLDLRDRVSMKLQDIRRHKANYLAKYLQDRLRDRM
DGRAKQEAEHQVGSTEHFNNERIEVAFRRAAHQYQVKPYAGAVTLFRPKPAVFYRLSGGR
CLKENRDILLLDNGWTEHVTQLTVSEVPGDHDSMVLDPYVRVLAERMRAVVAEAVEKRRL
QEAGSAQLVQRTSAALNPVIELA
>A0A2X1U7Q9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium xenopi|TrEMBL
MSDQQSAALPGDTDPIVIIGMAVEAPGDIDTAEAYWALLSQQREALGPFPTDRGWPIRDL
LAGSCRDGFKKIHDSGGFLTGAATFDPAFFGISPREATTMDPQQRVALRVAWRALENSGI
NPDDLAGQNVGCYVGASPTGYGPDMAEFSRHSGHLITGTALSVVSGRIAYTLGLAGPALT
VDCSCSSALAALHVAVQSLRTGDCDMALTGGVCVMGSPGYFVEFSKQHALSDDGHCRPYS
ARPSGTVWAEGAAMFVLQRKSDATRDGRRIVGEIRASAVNQDGRSAGLSAPSAAAQTRLL
RRAMAQAGLHPDDVAMVEGHGTGTQIGDRIELHSLSQTYGDTEPGRGALLGSVKSNVGHA
QAAAGGLGLAKVLVSAEHGAVPATLHADEPSREIDWESQGLRLARTLTPWPEVDGQRIAA
VSAFGISGTNAHVIVSVPAVA
>A0A378SQ70|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium gilvum|TrEMBL
MRVSGDPVVIAGMALEAPGGIDTPDAYWAMLAEEREVLGPFPTDRGWAVRDLLDGSRREG
FKRIHDRGGFLAGAAQFDPEFFGISPREAVAIDPQQRVALRVAWRALENAGINPDTLAGR
EVGCYVGASYLGYGGDLAEFTAHSGHLLTGTTLGAISGRIAYVLGLGGPALTIDASCTGG
LAALHVAVSALRAGDCDVALTGGVCVLGSPGYFVEFSSQHALSDDGHCRPYSAHASGTVW
AEGAAMFVLTRRSVAQREGYPVLAEILASGVNSDGRTKGMTAPSGDAQARLFRRTLDLAG
VRPDQIGMIEGHGTGTRLGDRTELHSLATTYGATRPGSGGVLGSVKSNIGHAQAAAGPLG
LAKVLVAAEHAAIPRSLHTDQPSREIDWETQGLTLATKLTRWPAVDGRRLAAVSAFGMSG
ANAHAIVAVPDGGTS
>A0A1S1NGX5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium talmoniae|TrEMBL
MASMQDLNDSSSGFAIVGYAARFPGAADAGEFWEVLRDGRDAISEVPEDRWDADEFFDPE
PGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREARLLDPQHRLLLETAWRAVEHSGTAPTA
LANTNTGVFVGLATHDYLGMASGELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV
DTACSSSLVAIHQACQALRLGECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA
AADGYVRGEGCGVIVVKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
DALKRAGLAPSDVGYLEAHGTGTSLGDPIEAQAAGAVLGAGRDPSQPLLIGSAKTNIGHL
EAAAGIAGVIKVILALENELLPQHLHFQNPSPHIPWDRLAVQVVQEATPWERNGRPRIAG
VSSFGFAGTNAHVILEEAPVPAGQPAVLPRPAAAPADRRFNILPLSARTPAALVQIADQY
RTWLNAHPEATLDDVCFTAGAGRAHFEHRAALVVNSKESASELLGALADDRPAPGLVRGV
SDDTPKTAWLFTGQGSQYPGMARELFDTEPVFAETLTRCAEVVADVLERPLLDVIFDTDG
PNSEETLRQTSYAQPALFAVEMGLARLWQSWGFDPDVVLGHSVGQYSAACVAGVFSLEDG
ARLMAERGRLFGSLPAGGRMVAAFAAAERVEALTDEFPTLSVAAYNGANTVLSGPAQDLD
QAVARLTADGVRCDRLDTSHAFHSALLDPILDEFESYADQFTYSSPQRILVCNRTGSAIG
RSVKLDGNYWRRHARQPVEFAKSVRTLADLGCKVLLEIGPQPVLTAAALRAWPDPATAPR
AIASLRRNTADHRQITEALADAYVLGHLPDFGAVRPGHVQKLDLPTYPFEHRQYWFRDNR
ERPNQQQHLGASSEAVRLLEDGRIEELAALLDGSGGDQQTLNVLTKLAAQHNQQRKTKSI
ADARYEFRWEKSASSEADGGEGSGWLLIGDDADALQPLVDALTARGHRHRIHGLPTSDAE
EEQLEAALRAAAAEEPALRILHVAALDSDAASSTDALARMQRRVLGGTRRVFRAAAAAEL
RTPIWLVTRGAQRVIDTDTVSPEQSCLWGFGRAASLEHPQVWGGLADLAHGTADEWSRLI
NQVAAEPRREDQVALRDQAVYVPRLVRRVEPASATPLALRDDATYLVTGGLGSLGLEIAG
YLAAHGARQLVLTSRRAPSEAAQRRIDALRDQHGCDVRVVAADVADADDVARLLATVRSE
LPPLAGIVHAAGEIGTTPLSTLDDAEVDRVFAGKVWGAWHLSEAAAELQLDFFLSTSSIA
SVWGGFGQTAYGAANAFLDGLAWRLRERGVPGISVNFGPWSAGMADAEARARLDQRGIRT
LSPADALAGMADLIAASAPQGVVARIDWARFLPLYQQAGRRAFLAELEGEVPGTAPVPTA
SGKTELVERLTNAPVQQRKKLLTDYLRNAVAEVTRVDSAEIREDAGFFDLGMDSLMAVEL
RRRIEQGVGKEIPATLAMDYPRLSDVVDYLLGDVLELGEQGSAKSRAQPAAAATRTDEPI
AIVAVSCRFPGAPNPEAFWEVLSGGVDAIREVPEDRFDIDEFYDPDPDTAGKTYTRFGGF
LDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEALERAGYSPAELRGSRTGIFAGVAA
NEYAHLLSAESIDKIEPYFITGNALNAISGRVAFALGLEGPAVAVDTACSSSLVAVHQAC
QALHSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGILV
LKRLSDAVRDGDRVAAVIPGSAVNQDGASSGLTVPNGGAQQRLIGTALARAGFAGGDVDY
LEAHGTGTPLGDPIEVQAAAAAYGAARDADRPLLMGSVKTNIGHLESASGAAGLIKVVLS
LQHGVLPQSLHFDNPSPHIPWDSLPVQVVDKSTPWQANGRPRRAGVSSFGFTGTNAHVLI
EEAPAQPASPDEPAADDDAAVVAPETDGRDETVNVLALSGRSPEALVALAQRYGSWLDNQ
PEADIADVCRTAGVGRSHFEHRAALVVDSVQSARDGLAELTENRLRPGVVRGECTDRPTT
AWLFTGQGSQHPGMARELFDAEPVFADTVRRCADAVDGILARPLLEVLFATDRETGGEAG
ETLKHTSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSLEDGARLM
AERGRLFGSLPDGGRMVAVFTDPKQVEEVATEFPRVSVAAYNGPNTVLSGPGEDLEQIVD
RFGNDGIRCSWLETSHAFHSELLEPVLGEFESYAARMQFAAPTLPLVCNRTGTVLTADTP
LDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAAPRAIVS
LRKGIGDRRQIAEALAAAYVSGHRPNFAALHRQSRRRLELPTYPFQRRRFWPKASAITVD
GPATSGLLGSAKDLASGDSVYTSRLSVRSQPWLSDHVIYGTVVVPGATYAAMALAALGPP
ARVKDVFFYEPIILPEKDSREVQLTLHPLEDGAGWKFQVHSRPYGVRDADWSLNADGTAV
SGADDEATPEQADPVDAAIERMERMRPQELFETFADMELSWGPNWSGSLKSLWLGEGEAI
GDISVGEELSEQLGTEPMHPVLMDLCTGVAFPAFPALRAAEQGVNDLFLPLRYGQVMLAE
KMPRRFYCRAKWHASELNAETQVFDLDFVDRDGRHLGGIREFTVKRAPREALLRGLGGDA
TRLLYTLGWHEVPIAPTSEDAGTPSGTWLVAGFGELAAALPGCIPCDRANDSELLGQLLA
QAHERGMPFTGIVWRSAGRKADESTAEQITRLEAEIENLLSAVQTAQADNSVKLPGGLWI
VTERAVATESGEPVDPVQAALWGLGRTILNEEPGLRSKLIDHDGSPEAVRLLTGLLAAPI
DEPELALRQGKALASRLLQWSRSGHLNVPRADDYALLPTERGAIDNLRLTETDVPPPDEG
YVQVRVEAAGLNFRDVLNVLGLYPGDPGPVGGDFAGTVTQLGEGVTGLAVGQRVYGTMQG
AFATRFNVPAQFLAPIPDGVSAVEAATIPAAALTVRLSFDWAKLNPGDKVLIHAASGGVG
LAAIQMAQRHGAEVYATASTFKRATLRKLGVKHVYDSRTTDFADQILEDTGGSGVDVVLN
SLTSEGFVEATVRATAKNGRFAEIAKRDIWTHEQMAEARPDIAYEIVALDTVMFTEPERI
RTLLSEVSDGLAKGEWTPLPAEIYPLTEARTAFRRMQQARHIGKIVCQMPNPLAPRRDRS
YLITGGLGAIGLHTASYLAQLGAGDIVLTSRREPDAEAQRAIEEIAERYKCRVHTFAADV
GEEPEVERLLERIRAELPPLAGVAHLAGVLDDALLNQQDLDRFRTTLAPKAFGAFHLDRL
TRDDKLDFFIVSSSVSSLLGSPGQANYSTANALLDGLIADRKAHGLPATGINFGPWGGGG
MASSEAASANISAQGLLPLDASGALGALAEVVANGTGQATVLKANWARAAKVLGSSRPPM
LDLVLPSAMTEVVDSELLRQLQEIPVAQRASFITEFLQREVQGFLRLAQPPAATSRFLDL
GTDSLMAVELRNRLHSQFGGAFTINATAVFDYPTIGGLGEYLANQLPDAESESAEAQGES
ASAEAESDAPSDEAEAVAAGEPS
>A0A853SAU2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Janthinobacterium lividum|TrEMBL
MPPFLDQIEHLSKPQLIALAAALREEILQLRPDESVDATSGDSLVYETRWCAMPLVSTAP
KHSRMLLITDSAAAPLTIPFAPHMQLSCMEIDASLGWTPELLAERLRGQAGQFDVVAYYS
AVETDASQPAPILLNHWCTALALATAVTGLVNAPRLWLITRRGQCLPDDTWTVDLGQAPL
VGLGKSLSLEHPAAWGGCVDIDGEPGALALAFAEIADGADDEVAYRAGVRYVPLLERLDE
ALPPPAPLRPDGSYLVTGGLGGVGSALVDHLLARGVARVVVFARGGHSMAASEPLLTGWR
AAYPRSRIDLIEVDLADVDSVSQGLSVLRRGEPVLRGIFHAAGSGAQVPLMQLDRAGIER
VVCAKALGALYLDTLTRQDALDFQVYFSSIAGSWGTASMAPYAMANRFLDVLSAHRNRHG
RLTRSIAWGPWASVGMIVKQNQEAYASLGLRLIEPARALHLLDRLIGVERAQVQAVDVDW
PRYAQSLGLDKHLRWFHQQIGTTPLPSGGATTAPQNEDFSGDNQTLDLLRDMVAQLLGEP
LRDGAELRPMRELGLTSLLSVELSQKIRHRLGIDCRATVVFDYPSLDALAKELSEKWSQA
NPAPTLVVQHPVAEQGVDERAIAIIGMACVLPGADSPEQLWERLEQAYHTGEDAIDRAPA
HRFDLARYSAAEDAPGKACNMAGGYLDDIAGFDHALFHLSRREAQFMDPQQRLALETSWR
AFEDAGIDPADLLSGDANGTNDAGVFFGIGQNEYGPLCRSVMDGEHTGLMPTGQSMNIIA
GRIAHVFGLQGPAIAYDTACSSSLVALDAAVRHLREGRNALAVVGGVNALVAPESFVLLA
KAGALSKHGRGAAFDMRADGYVRAEGCVVLVLKRLAEARADGDMVHAIIRGSAVNSDGRS
GGLTAPSGRAQEQVMGAALRDAGVTAEQVALVEAHGTGTRLGDPIEYHALRAVYADPIPR
TTPLQLGTLKSFIGHTESASGLAGLLKLVLSLRKRVMPAQLHYATLNPFIEASDRIEIPS
VARPLEAGGRLLGAISSFGFSGTNAHVIVERGDDGISRRIPARPFARVRCWYSERSLPDS
TGLAQVFGLPALLENVPDCYVRRWQAPEVEPGELVSNVLLIRPHGAGELYHRVREALLVR
GVRIVEAGHDEMADLRGSFDRVVLCLEALQPLVDRATGWLDGMAGTWSAMASLLTAPVAM
GHLLVFDASGGFVGDSVSQWSAVLACGTKERPGFSATLVQCEGDAVSRLQHHLDWLFATT
EPVCVLSRDGVEVPRLERVALAPDDALVLAADRSYLVSGGLGGLGASLIDWLLERGARHI
INLNRRTPNAEQAQALQLLAHRHGARIEALTVDLSDLEGMRRVLGAVLPGMPSLAGVFHC
AGTLDEDLIEQQSWQRAQAVLRSKFVGAWNLHLTTLHQPLEYFVVFSSLTVLLGQAGQAS
YALANALAERLVVHRRALGLPGLAIQWGPWSGTGMASRAGLASSYRNLGLASFGAGTYLP
VLARLLAMGTKDVTVPAQVGVFQMNWERYFSIAPRTPLCTGLHLSVEEKAGGEDKPSLAH
RLAGVAQERRLRLLRDLLKQMVADCLNLASVSVISDQDGFAELGIDSLHSTFLQKRLENE
LRSALPPTTVFDHPTTAALAAFLAAGPLRQLFQAEVVLADTEDERMDGLAEEELAGILAE
DIKRLNQLGATS
>A0A7X6AW53|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces malaysiensis|TrEMBL
MLRTDLIRPVPELLRANADRFGDKPACSDGHRTVSHAELERRTRRLAGHLAGLRLHPGDR
AMICLGNRVETLESYFGVLRANAIAVPVNPRSTDAELSYLLGDSGARLVLTDAAHADQFD
RLREQIPELRVVVSGDGPLPKGFIAYEPLPDTEPELAARDDLGLDEVAWMLYTSGTTGLP
KGVLSTQRNCLWSLAACYVPVTGLTAEDRVLWPLPLFHSLSHIVCLLAATAVGASTRIVD
GVATADVLEALREERSTFVAGVPTLYHHLIEAARERDFAAPELRVALVGGAVATADLVRS
FESTFGVPLVDAYGSTETCGAIAVNWPTGPRVEGSCGLPVPGLTVRLVDPDTGADVPAGQ
EGEFWVSGPNIMAGYHNQPEATAAALRDGWYRTGDLGRRDKAGFCTVTGRIKELVIRAGE
NIHPGEVEAVLRTVPGVADVAVVGKPHTVLGEVPVAFVVPGPEGFDPSALLATCRERLSY
FKVPEEIYEIARVPRTASGKITRHVLLELPARLRAAGDGQYDSLLRLDWVPQPALPDAPA
GAGTWALLDGDALGLAEGLRAAGVDARVVAEGVGGSVAGLVADSVADLVTDSVADLVADS
VDGLVTDSAGGGGRPAPDVVVVAPPAAGLPDAGQDLVDGLAARLGGWLADDRLAATKFVV
ATTGAVATGTEADAPEPLSAALWGVVRSLQAACPGRLTLVDVDVDVDVDLDTDVDVERAG
AGEGDGDGRGAALRRAVENGHDQAAVRTGVLLVPRLTRVSVPAEPGPAPVLDPDGLVVIT
GGDTARGTALARHLVAGYGARNLLLLSANGLPEEAAAALRSELAHDGAQVSMAVCDPADR
AALDSVLDAQDRPVIAAVHIEEPGPERSFDTSLRGMTHLEERTRRADPALFVVVTSAAGV
LGSPGRPDRAAADQFGEALVRRRRALGLGGLALAWGPLPGEHGTAPVAGAVPLPEALALF
DAALTADQGPLVLLRPSTQGLPGGEPVPAVLRHLVDAPSAVPTSDEPAAAEFRRRLAAES
ESGRQRTALALVREHAAAALGLASADPVEPGQAFSAFGFTSLTAVALRNRLNAATGARLA
ATVVFDHPTPAALARHLVREITGRRSEHAPVRARGVSDEPVAIVAMGCHLPGEVRTPEDL
WRLVSDGRDAIGGFPEDRGWDLAGLFDPDPDAVGKSYVREGGFLTDAGGFDAAFFGISPR
EALAMDPQQRLLLETAWETFENAGIDPSSLHGTDVGVFSGVMYHDYGADAGSAAEGLEGH
LGVGSAGSVVSGRVAYALGLTGPAVTVDTACSSSLVALHLAVQAVRTGECSLALAGGVAV
MSRPTSFIEFSRQRGLAPDGRCKSFAEGADGTNWSEGVGLVLLERLSDARRNGHQVLAVV
RGTAVNQDGASNGLTAPNGPSQERVIRQALANAGLTTADVDAVEAHGTGTALGDPIEAQA
LLATYGQERSEDQPLWLGSLKSNIGHAQAAAGVAGVIKMVLAMRGGVLPKTLHVEQPTSK
VDWASGAVSLLSEARPWPETGRPRRAGISSFGVSGTNAHVVLEQAPEAVVPAAEADDAGT
PGLVATGGVVPWVLSAKSPSALRAQAERLVKRLELGDAPRAVDVGWSLATTRAALEHRAV
ILATDTESGTETARALAEGRPDPLLITGQTAADGKTVFVFPGQGAQWVGMGAQLLDASPV
FAERLHECAEALAPYTDWSLIDVITGAPDAPSLDRVDVVQPATFAVVVSLAALWQSVGIH
PDAVIGHSQGEIAAACVAGHLTLPTAAKIITLRSQTIAHHLAGHGGMMSLAAPADTIDLT
NWHGKLWIAAHNGPNATVIAGDTDALHELHTHYTDQGIRARIIPVDYASHTGHVDTIEDQ
LDHVLNGVTTSTGTIPWLSTVTGEWIGPHTADSGYWFRNLRQTVQFDTTIRTLADDGYRT
FIEISPHPVLTTAIQETLETTNTPNPTVTGTLRRNDDTPTRFLTHLAHLTTHGHTPNWTT
LYTHTNPQHTPLPTYPFQHHHYWLPRNTNAGDVSAVGLQDTGHPLTGAVVSVPDTGGVLL
TGQLSVATHPWLADHAVSGTVLLPGAAMAELAIRAGDETATPTLEELVIGQPMTLPDDGA
LHVQVLVGGEEGGRRGVRIYSRADSAQEWLEHASGTLATQPDGAAEDGLAEWPPPGVEPV
ALDDFYDNLAQAGYVYGPAFRGLKAVWKRDGEVYAEAALPEEPTETAGRFGIHPALLDAA
LHASNFCVSPAPGQTLLPFVWNDVRLLAAGATAVRVRARATGPDSFTISLFDTTGSPVAS
VDSLVLRAISPEQLAAASSGVDRSADSLFTLDWTEHPAAPGSEVSWATLGDGHADDLDAL
IAAEDRPDRPEAVVADTTAWATEHTSLPARARDLAARALDLVQRWVGRPELADVRLVLLT
RGAVSVHDTAEVTDPAAAAIWGLVRSAQSEHPGRIALVDTDDVSREALTVAVASGEPQSA
LRRGLLWVPRLVRSPQGLAVPAHEHWYLDVSEKGSLENLVLRPDPEATAPLAPGQVRIEV
RAAGQNFRDVLVALGGVAGQEGLGGEGAGVVSEVGPGVEGLAVGDRVMGLFPRSFGPLAT
ADARTVAPIPEGWSYATAAGVPVAYLTALYGLRDLGDVQPGETVLVHAAAGGVGMAAVQL
ARHFGATVYATAHPSKHHVLTALGVPEGHLASSRDLGFASAFPSLDVVLNSLTGEYVDAS
LGLLGSGGRFVEMGKNDIRDPAAVAEAHPGVGYQAFDLGGDAGPDRIRELLAELVELFRR
GAIEPLPVRHWDVSQAPAAFRWMSQGRHTGKIVLTIPRTLDPDGTVLVTGGTGTLGATIA
RHLITHHGARHLLLISRQGPNAPGATDLATELTELGATVHITACDTADRHHLTTTLANIP
SDHPLTAVIHTAGTLDDGILTALTPERLDTVFRPKIDAITHLHDLTHDHDLAAFVVYSSA
AGTLGNAGQANYAAANAFLDAFAQWRHARHLPATSLAWGLWSDTSTLTATMDAADVRRTR
RAGVLGMDNAEALRVFDTGLRSGLPALVAAKVDVTALRAPDAELSPLLRGLARPARRTAR
TAAPAAGGLSGQLAGLSPTGQREFLLNLVRAEAAVVLGHTGPEAIEPTVAFKEMGFDSLT
AVELRNRLNSATGLRLPATLLFDHPTPALLAELFRAELGGDPAPAKAAPAPVRTAADEPI
AVVAMSCRLPGGVTDPDGLWDLLLGERDGITDFPRDRGWDLEALYDADPDHSGTSYVLRG
GFLEDAAGFDADFFGISPREALAMDPQQRLFLEACWETFERAGMDPTAVGGRDIGVFAGV
INQDYGVRSGPAPEDLEGYLLTGSATSVASGRVAYVLGLEGPAVTVDTACSSSLVAMHWA
VQALRQGECSMALAGGSTVMGRPSAFVEFSRQRGLAPDGLCKAFGAGADGTTFSEGVGVL
LLERLSDARRNGHEVLAVIRGTAVNQDGASNGLTAPNGPSQQRVIRQALANAGLTAADVD
AVEAHGTGTALGDPIEAQALLATYGQERQGDEPLWLGSLKSNTGHTLAAAGVSSVIKMVL
AMGHGTLPRSLHANEPTPEVDWSQGAVSLLTETRPWPVNGHPRRAGISSFGISGTNAHLI
LEQAPQPESEDMSRTDDGTDTPGLVATGGFVPWTLSARSPAALRAQAQRLLDHLESGADA
HPVDIGWSLATTRTLHDHRAVILTDTTTESTETTAALTALASGQPHPRLTTGHATTHGKT
AFVFPGQGAQWAGMGAQLLDTSPVFAARLHECAEALAPYTDWSLIDVITGAPDAPSLDRV
DVLQPTTFALMVSLAALWQANGIHPDAVIGHSQGEIAAACVAGHLTLPTAAKIITLRSQT
IAHHLTGHGAMMSILTTEEWAQEALAPWHGRLWIAAVNGPTSLSISGDPDALTEFGKTLS
KAKVYRWQLPGVDFAGHSGHVDTIKNQLHQALDGVTATPGHTAWMSTVNADWADPTHINA
DYWYRNLRDTVHFEQGTQALLTQGYRTFIEVSTHPVLTTAIQDTTETHPDTPTTITGTLR
RDDGGPDRFLTSLAELSTGGVPVHWPTVYAGTTPSRIPLPTYPFQHQHYWLAATGHTGDV
GSVGLREAAHPLLGAVVSVPDTGGVLLSGRLAPSAQSWLADHMLSGVALLPGTAIVELAV
RAGDETGTPVLEELVLGQPMLLPEDGALQVQVLVGAAEDDGRRAVRVYSRGDESEPWVEH
ASGVLSPQPVAPVEVAERQWPPAGAEPVALEGFYDRLAQAGYEYGPVFRGLTAAWTRDGD
VFAEITLGEEQHELAGRFGIHPALLDAALHASNFCPGNEPGAGTYLPFSWNGVRLHAAGA
TALRVRVSSTGPDHLSLHATDPHGVPVVTVGSLVLRETTAEQLSSTSAPSTADSRFTVEW
TEHPLAEHEVSWAELDAVPDNDTWPPVVVADTRTYATEDGELPERARALTGRVLTAIQRL
ISDDGLADSRLVLLTHGGMAVHDETEVTDPAAAAVWGLVRSAQAEHPGRVCVIDTDDRSA
GALPTALATAEPQLALRGGTAFVPRLVRVHPGLAVPAAAAWHLDVTEHGTLENLALVPHP
RAEAPLEAGQVRIAVRAAGQNFRDVLIALGMYEAEIGTEGAGVVTEVGPDVADLAVGDRV
MGMLPGSFGPLVVTDRRTVVRMPRGWSFTAAAGVPVAYLTALYALRDLGDVQPGETVLVH
AAAGGVGMAAVHLAHHFGATVLATAHPDKHHSLERLGVPAERRASSRDLGYARTFPAADI
VLNSLTGEHIDASLELLGPGGRFIEMGRTDIRDADEVGAAHPDRTYRAFDLGADAGPDRI
QELLAELVGLFERGLIPPLPTRPWDITRAPDAFRWMSQGRHTGKIVLTVPRTLDPDGTVL
ITGGTGTLGAAITRHLVTQHGVRHLVLASRQGPNAPGAAELHDELTALGARVRITACDIA
DRGQLATLLGDIPADHPLTGIVHTAGTLADGTITTLDPDRVDTVFRPKVDAITHLHELTR
HQDLALFAVYSSAAGILGNAGQANYAAANTFLDAFVQRRRAAGLAGLSLAWGLWAETSNL
SAALTTANRDRTPAGVVRPMSTEHALNLFDDALGLGLPLVVPAKLDPGSLRDEPAPGAVS
PLLTGLVRPARRTLRSGQFAEGGLAARLAALSEADRHRLLLDLVREHTATVLGHTGKDAV
DARRAFSEIGVDSLIAVELRNRLSSATGLRLPATVVFDYATPEAMAVHLRSVVAGDTATP
STSAVAPASAVAPADDPVAIVSMNCRLPGKVTGPEELWDLVFQGRDAIGPFPTDRGWDLE
TLFDLDPEAVGKSYVREGGFLTDAGEFDAEFFGISPREALAMDPQQRLLAETSWELFERA
GIDPTSVRGQSIGVFAGVIDQGYFGHSQAPQPELEGYLMTGSTTSVASGRVAYLLGLEGP
AVTVDTACSSSLVALHLAVQALRAGECSMALAGGVTVIAKPSGFISFSRQRGLAPDGRSK
SFSEGADGTTFSEGIGLVLLERLSDARRNGHEVLAVIRGTAVNQDGASNGLTAPNGPSQQ
RVIRQALANAGLTTADVDAVEAHGTGTALGDPIEAQALLATYGQERSEDQPLWLGSLKSN
IGHTQAAAGIAGIIKMVLAMRHGTLPQSLHADEPTTKVDWASGAVSLLSEARPWPETGRP
RRAGISSFGISGTNAHVILEQEPEAEAAETETDDAGAPGLVATGGVVPWVLSAKSPAALR
AQAERLVKRLELGDAPRAVDVGWSLATTRAALEHRAVILATDTESGTETARALAEGRPDP
LLITGQTGTNGKTVFVFPGQGAQWMGMGAQLLHTSPVFAERLHECAEALAPYTDWSLIDV
ITGAPDAPSLDRVDVVQPATFAVVVSLAALWRSVGIHPDAVIGHSQGEIAAACVAGHLTL
PTAAKIITLRSQTIAHHLAGHGGMMSVLTPHEQVEETLTQWQGKLWIAAHNSPQTTVVAG
DTDALHELHIHYTDQGIRARIIPVDYASHTGHVDTIEDELHQALADTTTQPGTIPWLSTV
TGQWTEPHTIDGGYWYRNLRQTVQFDTTIRTLADDGYRTFIEISPHPVLTTAIQETLETT
NTPNPTITGTLRRNDDTPTRFLTHLAHLTAHGHTPNWTTLYTHTNPQHTPLPTYPFQHHH
YWLQPSEVPEAVADGVFWDAVERGDLATLADSLGVEEKTLEPVLPGLTSWRRRNQDQSTV
DSWSYRIAWDPVATGEPPSLPGAWLVAVPAPQANDDSVMGLVAALAEHGAEPVVVEVDTV
DQAELTACLRERLADSGDEYAGVVSLLAWDERSCEPGTLSRGVAATVALMQAVEEIGLAA
PLWCLTHGAVAVREPSEVTSEFQPLVWGMGVVQGLDQPTTWGGIVDLPQTPDETALARLC
SVLAGVDAEDQVAVRASGVFARRMRREPVTSAPVWRPRDTVLITGGTGGLGSYVARWAAD
HGARHLVLLSRQGAQAPGAAELEAELTALGADVTIAACDVTDREQLAAVLAELPDGAPLS
AVVHAAGLALPEKPLSKMTLAEFADIGRAKIAGARHLDNLLWDRELDAFVLFSSGAAAWG
SGGQSAYAAGNAYLDGLAQRRRARGLAATAVAWGAWGGGLGTIDEMMGAQWRRTGLMTMD
PRLAALAMAHTVGGGAVHGVVADIDWERFAPGYTMARFRPLLRGLPDVIDLLTEDTSEDG
AGQTELIARLAGLTPEEQERLLTELVQAEAAAVLGHANADATGDRPFSEIGFDSLTAVEL
RNRLNAATGLRLPATMVFDHPRPSVLARRIRAELGQADTSSVDSVLAELERLEAHLAALP
KEKIERARITSRLQRMTTKVAEIEAVGAGGETVTERLDTASADDVFAFIDQEFGVD
>D9SRA9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B)|TrEMBL
MRELYTLILQNTKAGNISKEAAAELLNKIKEKFINNKENDLAIVGMAGRFPEADHLEEFW
ENLVEGKESIREFPADRRKSVENYIKVFSKSDSERLRIAGYLEEIDKFDNDFFGISPKEA
ALMDPNQRILLENVVHTVEDAGETFEALQGSNTGVYIGYSTDFGTEYKDMINVVDTLDGF
AATGNTYSVLAGRISYLFDWIGPSMVIDTACSSSLVALNKACDDLRNGACNQAIVGSIKA
VPILGLQSELEFGVGSSTERTFPFDNRSDGIAFGEGVGCIMIKPLANAIKNNDRIYAVIK
GGSVNQDGNSMALTAPNPLSQKKLILQAAKNANVSLADIGYFETHGTGTKLGDPIEVQGI
TLAFKEQTDKKQFCAIGSVKANIGHLDCAAGIASVIKCALQLKHQTIVPSINFEIPNKNI
DFMHSPVYVNYKTCKWRVDPKKTRKCCISSFSVGGTNSHIILEEYQPPQEELFANKQAVK
ILTLSAKDESVLKQLVKDYKSFLNKNREINLMDLCYTANSCRQSYIYRLAIVFNDLNELL
RKLNTYQEVGQVEGVYVGKAERNENNGDVLINQFKTKQMLDEQVACQIAESYTKGNHIDW
TLMYADELVRKVTLPLYPFRKNRCWIDLDETTLANHRYVAKQEEKDAFILVGKDTFTKIE
VDIARCFYQLLGVKQVDINDCFFELGGNSLLAIKFELEMKKLNYEFSYKDLNKYETVKKI
ANFIESKNNDTPLMNKVIVYEGIKPFNDIFFRDCFYNSFFPILQRNKKSIMPFMLNAYPI
YKLDQQLISVEYDVIQGFEALCKQEHITYETFAKVDDIVGEIESGLSHEQLIIVFIDCYY
ETFRKDTYNKLHWPHTLLIYGMDVENKKFYVLEHTNKDNLGYKNCTLDYQDVIDSYRGCY
ENFPNMFKYGLYKFNIENGEPLEDETQVMTEVAAQNILAIYDKVSESNKVLDCFKDYFKK
ILGSEQNLIENSQNLVTNLNNLINIKRAELYKYEQLPIFKQACNQLKTIINNWEEIRDAL
FYCLFANEYNNETLLPLNEKLKQVISLECEYTKILYDVSTQITK
>I3WYT3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Sinorhizobium fredii (strain USDA 257)|TrEMBL
MTVEIIGRACLAPGAQSPQALFKILRQGMCTVTSVPGDRWDLARFWHPVMGTQGKTYSFA
AGVLETIYDFDPAVFGMSQREAMYMDPQQRVLLQLAWRALEDANISIASLHGENVGVYVG
ASSLDHANLTVEDPAAAGPYFMTGNTLSIVSNRISHVFGLSGPSMTVDTACSSSLVALDQ
AMRALNAGEIDTAIVGGVNILAHPLPFVGFAQARMLSPEGLCRAYDNDGAGYVRAEGGVV
FVLRRSDRARRERDRSYARIVASGVNSAGRTNGISLPSREAQANLLKAIYEGNGIDANQV
AFVEGHGTGTKVGDPAEVWSIGTVIGAKRRAPVPIGSIKSNIGHTEPASGLFGMMKAVLA
LEHNYLPASLHFDTPNEHIDFDSLNVRVTANPIELLKGKRARLAGINSFGFGGANAHVVI
SDPDPVPQERATAGSAGQVFLASAHTQSSLENLLRDYKATFAGASKEETRAIIAASGANR
THMRHRFAARSDHPEDIVRAIASYLEKPGSDIGEVGEAPLKNAQVAFVFSGNGSQWAGMG
VEAFRENLHFRQSFTSVSALFKFHSDIDLKDLLTDPELDKRLADTKVAQPLLFAIQAALS
DSLVAMGIKPTAVFGHSVGEIAAAYAAGALSLVDAVSIVAKRSLHQDLLAGEGTMAAVML
GEEAAAAFAQARGLDEVCVAAVNAHNSVTISGPAHEVTAFRDAARKAKIPVQILDINYPF
HHPIIDQAKEAFLADIPDIAPRRTELTYLSTVTGSALDGTELEPDYWWRNVREPVRFQAA
TDAALVLGCRLFIEISPRPILASYVKETIKQAAVPAAVVPTLLRDDGERGQDPISASMAR
AVAHGAAVDRPRVYGKRDAFIELPSLPFEPIELRPQTTTDATDLFGRSGKAYRLIGWRGD
PNSGSWKNHVDAHLFPDLAEHVVDGKAILPGSGFIEIAVSAAQQYYGSDEVEITNLEIVR
PLELSDSRIVELSTILSPETGDIEIRSRERLSEDDWTVHAVARSRKPIAGANGRHPPISG
LAKTGIVTPARAYDTAKHFGLDYGPHFQLLTRAVAYGERLIDVELKAPAGSGHPLVSYAL
HPISVDATFHGLVALFDRFTGDKGGAPYIPVRFGSVRVVNAGRPIARATVEIDSVSANSI
KARFHFFDAAGEPIAHFDDCRFRRTYLRKHKTLDSLSFHYEAVLSDVILPGTKRAGAVPA
KLTEPAAANSGVDNATLLFNAAIYRACHEIAHKLARGKSTIPDNRLPGDFAFQCFLTNCF
YALEDAGLCEHQNGSWRVAPEFTLPSVEEILGELYGERPDRAVEAVLINNAYAEALSRLD
MLLARTADGETAAFNAGFISEATLDHQAVHSVASRSRMDQVLGMVEQALDAQVGGARLRI
VELGSVSAGFTRRLADLAARHGTTLSVVEPRDNAQRNLEIAFEEDAHVRILKKSEFAAIG
PFDLAVSASDNLYPLIEEEAGVRSALRSMLRESGALVAAVSAPSIFGDFAFGLSDGWFQR
SQTAEFPIGRLAAASHWQKCLADLELNEVDVSDCECPHGHTILIEARGTSIATGPMTSEA
GVVPFLLIETGTLPSSVPAEAIPVVVSGDMAADVAALGAALDRLDGTPVRAVFVSATGDQ
IGDEDSDLLQTQVLALSAFAEALKQRVGNGEPAGAERPRLVLVAPGGAPVSESASSGVNS
GLWTFVRVLQNEYEFLDVHALDVCDHAETDHVELLASALPLLAIEGSNREWLLDRKTGLV
SEIRAVSGPAAKTEGKTGAFPAATIRQRVSSQVSSIAWEETDVPRAGLGEIVVSVAATGL
NFRDVMWAMGLLPEEALEDGFAGATIGMELSGHVVEVGEGIDDLAVGDAVMAIASSAFST
HAVVSRAGVAKLPQTISPVAAATLPVAFLTAYYAMVELGRIRAGETILIHGAAGGVGLAA
LQVAKLKGANVIATAGTREKRRFLTMLGADHVFDSRSLGFVNEVRAVTGGEGVDLVLNSL
FAEAMEQSLALVKPFGRFLELGKRDYYADSKIGLRPFRRNVSYFGIDADQLLVNQPELTR
RIFMEIGELFDEGRLTPLPYRAFDFDEIGNAFRLMQNAGHIGKIVVLPPVAGQHEIAAKR
RRGMKVDPDGMHLVVGGIGGFGLMAANWLVEKGARNIALCSRRGQPDAATSAMIDRWKKA
GVAASLHACDVTDAAAVETLLATLRSQAPLRSIVHAAMVLDDALISNLTRGRNRPVIDVK
AKGAAILDRLTRADTLDNFILFSSATTLVGNPGQANYVAANGYLEGLARARRSEGLAGLA
VGFGAIADAGYLTQNAEVNDLLAKRIGKTALKAQVALDMVESHIAADPGSVDAAVVMISE
IDWAAARNLPVARNALFEVILRGADQHASGAEGTKLDLVAMIEGKSPQEAEDILFDLVAS
EIAAILRVAKDTVTRGKILKEIGLDSLMAVELGISFQQNTGFDMPLSGVADSTTVGDVAR
KLYEKVSKRDQSDEAETTDDKLVTELTQRHIGAAKEKALSQ
>V5ZDI8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Erwinia piriflorinigrans CFBP 5888|TrEMBL
MSIAIVGMQGVFPDAGNVDVLWQNIRSGKISIPSFAPTVEEKPGETWVHRRPLLNNPQWF
DAAFFGYSDIEAEALDPQLRMLMEQAWLVLEQAGGCEQQQRLRTGIFAGTRHSRYLEQHL
QHSPRHLAALGADYLQMMNRKDSAATLLAYRLGLGGPAISVNTACSTSLLAVHLACNSLL
TWECDIALAGGAAIPVFAPESQLAVPGGFLSPDGFCRPFSQRANGTIDGAGVAVVALKRL
EDAERDGNAIHGVILGSAVNSDGNDKVGYAAPGVSGQTRVISDALAVSDVDVNNVGYLET
HGTGTQLGDSIEISALKKAWSSHTDRTGFCALGSIKANIGHAGAAAGVIGLIKTCCAVRD
GIIPPLSQCETPHPALKLAQSPFRIPHQEERWPSQFPVRQAAVSSFGIGGTNVHLILQQP
PENTPRPEVNPQPSLLLVSAKTASSLVAQCQQLASVLVNRKDADLPGLAATLALTRNHFP
YRLAVAAEEIGQAVKKLQAVTVSGVIPTPGQREKSVLMFPGQGSQHPQMTLGLYRQNAAY
RHWLDRVAQSMQREGVDLMALLESDADTLQATANAQPVLFATGWALAQWWRQHGVEPALL
IGHSIGEWVAACLSGIFSLDDAVRLVCLRGRLMQAAKPGRMLSVDLDANSLQSLLTPGLE
IAVINQPKACVVGGDEAELALFEQQLESQGIGCRRLRTSHAFHTASMAPAAEAFAQALHA
TPRQPPSIPIISNLSGELLTDEQACSARYWADHIRQPVQFARGLATAVDQGAELFLECGP
GTVLASIAQGAGVVDVPVIGSQPHASRTTLSAVALLQAAGELWLKGVSLDLPALIGTHID
LQRYQLPGYAFERHDHWVKPHPVADMTVLSQLLAERGVRLTLDGEHFQSGEEINALFRQL
TAPQADPVSPPSARSNSMNTSALPSPEIDNDIQQQITAIWQEVLAVTAITPDDNFFDLGG
NSLWALQIISKVNARFGCEIHLTELLNAATIGDLTRLVEQRLFSSVDEDELNLLLSELSE
EELESLLQEEQGRAG
>A0A099KHF9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Colwellia psychrerythraea|TrEMBL
MQANNNFRETIMAKKQSTSTNPVTKEEDEQTFNSRLQECPIAIVGMASIFADAKNLENYW
DNIFESVDAIKEVPSDRWVKDDYYSSDPKEADKTYCKRGGFLPEIDFDPMEFGLPPNILE
LTDIAQLLSLVVAREVLNDAGIGDGSGYDRDKVGITLGVGGGQKQISPLTSRLQGPVLEK
VLKASGVEEADRAMIIEKFKKAYIGWEENSFPGMLGNVISGRIANRFDFGGTNCVVDAAC
AGSLAAIKLAISDLLEHRSEVMISGGVCCDNSPFMYMSFSKTPAFTTGEDIRPFDNDSKG
MMIGEGIGMMAFKRLEDAERDGDKVYAVLKGIGTSSDGRFKSIYAPRPDGQAKALKRAYE
DAGFEPKSCGMIEAHGTGTKAGDAAEFGGLVKHFSQDNEQKQHIALGSVKSQIGHAKAAA
GAAGMIKAVLALHHKVLPATLHIDQPNTALDIENSPMYLNSETRPWMAREDGLPRRAGIS
SFGFGGTNYHMVLEEYSPKAQGQYRLNAVPQTVLVTATDEKALVNALMEWKNKLSVNADD
QPYAFNALVVENTLTTPAIDLARCGFVAKNADEAIKMIEGALKQFQAKSGSEEWSVPTGI
YYRKSGLATTGKVVALFSGQGSQYVNMGRELACNFPSVMQAAADMDSEFSQAGLGQLSPT
TYPIPVFNDDARKAQDEVLRLTQHAQPAIGTLSVGLYKAFTNAGFKADFTAGHSFGELTA
LWAAGVLSDSDYMMLARSRGQAMAAPTGEAAIGFDAGTMIAVVGNPAEVAEDIKDIKDIS
IANYNSNNQVVVAGVTSQIAIALDVLKGKGYKVVPLPVSAAFHTPLVGHAQKPFSDAIDN
AKFNKPLVPVYSNGTAKAHSNKAAEIKKSLKNHILESVHFNEEIDNIYADGGRVFVEFGP
KNVLTKLVENILKDKEDVVAIAVNANPKKSADMQMRQAAVQMAVLGLELTEIDPYSAVKR
PLSAPKMSALAMKLTGASYVSPKTKKAFDDALSDGWTIKQATSVPVAVPEPQVVEKIVEK
IVEVERIVEVEKIVYLNSDGSVADGTVANGQAVNNVAANVNSADIANSIERSVSQFVDHQ
QQLLNVHEQYMQGPKDYAKTFDAVLSSQEAGELPESLDRTLGMYHDFQSETLRVHEQYLN
NQTENMAAMLSASENSTEVTANLVKTSPTTTQAPTGKSAVTQAPVVKPTTPVAPTTQPLP
AAVSSPVVNAPVVNTSVPTQTVATAVAMSPVAEASITVPVQEPSIELETLDLQKIQTVMM
EVVAEKTGYPTEMLELEMDMEADLGIDSIKRVEILGSVQEIIADLPELNPEDLAELRTLG
EIVSYMKGKMKSKAQAAAPSASANDSAPALHLVETSAVTAPAIDLTHIQNVMMEVVAEKT
GYPTEMLELEMDMEADLGIDSIKRVEILGSVQEIINDLPELNPEDLAELRTLGEIVSYMQ
SKVSAAPVAAVDSTPATVQTNASSAPAIDLVPVSLSKVQNVMMEVVAEKTGYPTEMLDLE
MDMEADLGIDSIKRVEILGAVQETIPDLPELNPEDLAELRTLGEIVTYMQSKVTAAPVAL
QASAPSVLSNETQNSAPAIDLVPVSLSKVQNVMMEVVAEKTGYPTEMLELEMDMEADLGI
DSIKRVEILGAVQETIPDLPELNPEDLAELRTLGEIVTYMQSKVSAAPVSAEASATANEN
SVSIDLDYIQSVMMTVVAEKTGYPTEMLELAMDMEADLGIDSIKRVEILGAVQETIPDLP
ELNPEDLAELRTLGEIVSYMQSKVSAAPVVVVDSAPSASANESVQTSVSSAPAIDLDYIQ
SVMMTVVAEKTGYPTEMLELAMDMEADLGIDSIKRVEILGAVQETIPDLPELNPEDLAEL
RTLGEIVSYMQSKVAPVADITVTVETSTLANDNAPAIDLDYIQKVMMEVVADKTGYPVEM
LELAMDMEADLGIDSIKRVEILGAVQETIPDLPELNPEDLAELRTLGEIVSYMQSKVSPT
DPTDPKGTGAKADVSAIDTDNSVEAAVNFQGAPSATVELTALSSVNKIVQDVTGEGKQSG
ANALVVDDGSGAAVALSAQLIKAGWQVTAIKPNWVVSQSKKAFAKAVNLVEIGTDDKTLD
EAQVKDIIEKTAQLDAVIYLQAANTIDAIEYPEAAKQGLMLAFVLAKLSNVKNASKARAS
FVVVTRQGGTLGFANGDVDSGTQQVKANVKADLVQAGLAGLVKTINHEWNSSQNNGEGSV
FCRIVDLSSKLAADKAATIINDELLDLDGSIVEVAHDTDNLSNNIGTRLTLSGVVTDSYA
LAPSVKGSSTAINSDSVFLVSGGAKGVTAHCVIEIAKQYQAKFILLGRSSFDANEPSWAQ
GISDEVALKKAAMQALIASGEKPTPVKVTQFVRPVLANREIAQTLTAIKAAGGQAHYAAA
DVTNSESVIAAVQPISKTLGQVSGIIHGAGVLADKFIEQKTLEEFNAVYTTKIDGLLSLL
AATNAENIKHLVLFSSAAGFYGNPGQSDYSIANDILNKTAYRFKAFNPSTQVLSFNWGPW
DGGMVTPELKRMFNDRGVYIIPLDAGAKLLVSELAADTNRCAQILVGNDLSKDKSKDTAK
DASVKKPQVSRLTTRVNKTLLATNNTFLADHTIGDDKVFPTVCAIAWMSDAAMVAYPAFH
YQGLANYKLFKGIIFDGSEATDYVIDMIAQVEGESLVVDTKISSTNEQGKPVFHYGAQLT
LVAKAQKEEAPTVELILPETSPEILSETVTASSENADALYTNGTLFHGESLQGIKAILEC
NEQGLLLRCQVPEVASLKQGEFPISPVNSANEHANIFANDIAYQAMLVWVKKQLGLGSLP
SSTDSWTVYRDVSFGENFTLKLTVVKSSGKGKQRGSLVADIEMIDENNRLLSEIKSAKVT
ASANLNDLFLPKEKHGASA
>G8SJL5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)|TrEMBL
MGDEEKLLTYLRKATAELRDARQRITELESAGTADDPVAIVAMACRYPGGVTSPEDLADL
VLDGRDAVAGFPDDRGWNVEGVYHPEPGEPGRTYTRQGAFLHDAAWFDAGFFGIGPNEAL
LMDPQQRLLLEISWEAFERAGIDPRSVRGSATGVFTGMMYHDYPEAHSTGSVASGRVSYV
FGLEGPCVTVDTACSSSLVAVHQAVQSLRTGECRLALAGGVAVMATMDTFIEFSKQRALS
ADGRCKPFAAAADGTGWGEGAGVLLLERLSDARRNGHPVLAVIRGVATNQDGASSGLTAP
NGPSQQRLIAAALADAGLTAADVDAVEGHGTGTVLGDPIEAQALLATYGADRPADRPLWL
GSLKSNIGHTQSAAAVGGIIKMVMAMRRGVLPRTLHVDAPSPKVDWSAGRVELLTEARPW
PAGERRRRAGVSSFGVSGTNAHVILEDVADEPAPDDTAPAPGIVAWPLSAASADGLRGQA
ARLAERLPDATPAAIGHALATGRAALSHRAVVVGADLPELLSGLAEVAAGEHEAGVSHDR
PAVVFTFPGQGAQWDGMAVELIETAPAFAAALERCADALAEFVDWNLLDVLRGVPGAPTF
DRVDVVQPVLWAVMVSLAELWREHGVEPAAVLGHSQGEIAAACVAGALSLADGARVVALR
SRVIATGLAGKGGMLSVPLSRAVAEQRIERFAGRLGLAAVNGPGSVVVCGEPTALDDLVA
ELTEAGLQPKRIKVDYASHSHYVAEIEAEVRAALAPVRPRPASVPFYSAVTGGLLADTTV
LDAGYWYRNLRQTVQFEDATRALLDDGHALFVECSAHPVLQVGLQDTIADAGAPAGTVES
LRRQDGGLRRFAGSLAAAWARGATVDWARFSPAARPADLPTYAFQRERYWMAPVAGADPV
SLGQQPLRHPLLGAAVPLPGTDGLVATGRVSLTSHAWLADHDALGAVLLPGTAFVELAIN
AGAQVGCGVLAELTVQAPLVLPDRGPVALQVLVGGPDEDGARPVAVHARAEGGDAPWVCH
AAGLLTPDDGGPAPGHPDDSWPPAGAVAVDVTGAYDGLLGRGYAYGPVFQGLRALWRRGD
EVYAEVALPEPAHADAALFGLHPAALDAALHAALLTSDPDGTVLPFAWTGVRLHATGATE
LRVRLAPAGTGSSIHLTDPAGRPVLSADGLVSRPVSAEQLAAPGAPRDVPYRLDWMPMPA
AGTAPPVRWREVGGLDELTGDDDLPDVVLLRAPAADPADLPAALRETGAATLATLRRWLS
EPALDGRRLALLVEPDTLLGDTVRGMLRAAQAEHPDTFLVLDHDGRPESLAALPDALAAG
EPEVSIRSGRPHLPRLVAAGPPDAAARPDPAGTVLVTGGTGGLGALVARQLTTDCGVRHL
LLTSRRGPAAPGAEELVAELTERGVQVTVAACDAGDRAALAAVLAAVPAEHPLTGVVHAA
GVLDDGLIAAQTPERLDAVLRAKADGAWHLHELTADADLAMFVLFSSVAATLGGPGQTTY
AAANGFLDALAAHRRAAGLPATAMAWGLWTGAGMGDRLREADVRRMAADGLPPLPVADGL
TLFAAALRTDAGHQALLRLDPVVLRAQAAAGELHPKLRALIRVPARRAAGETSLPRRLAG
LGRPERLALLADEVRRRAAAVLGFTDPAGVDPGRAFRELGFDSLASLQLRNALNALTGLR
LPATLVFDHPSCAAVAGHLDELLMGAATADDRAGDRVATADGEPIAIVGIGCRFPGGARG
PAGLWRIVDEGADVIAGLPADRGWDLDNGYHPEPGTPGRHYARGGGYLHDAAEFDAEFFG
ISPAEALTMDPQQRLLLEVSWEALEHAGIDPATLAGTDTGVFAGLMYHDYPLNTATGSIA
SGRLAYTYGFEGPAVTVDTACSSSLVAVHLAVQALRRGECGLALAGGATVMSTTETLVDF
SMQAGLSPDGRCRSFAAGADGTGFAEGAGLLVLERLADARRHGHPVLALISGTAINQDGA
SNGLTAPNGLAQQRVIRAALADARLTAADVDVVEAHGTGTVLGDPIEANALLATYGRDRP
ADRPVRLGSIKSNIGHAQAAAGVAGVIKMVEALRHDTLPRTLHAVQPSPHVDWDAGAMRL
LTEPAAWPGGDRPRRAAVSSFGISGTNAHLILTEPPAAAPAEAPVAAGAPVVPWLLSARS
PQALREHAAGIARVAAGLRPADVAATLARRAALPHRAVLAVADPAEGIAALTALAAGDPA
APPVETAATATGCVFLFTGQGAQRLGMGRGLYERFPVFAGAFDEVLAGLVPGLRDVMWGG
DAAALDRTGHAQGALFAVEVALFRLVESWGVVPAAVAGHSIGEVAAAHVAGVLSLSDACA
LVVARSRLMQALPVGGAMTVVEASEAEIGPYLGRVDLAAVNGLTSVVVSGAADAVAEVAA
VFAGRGRRTRALRVSHAFHSAHMDPMLDDLRDVAAGLEAAAPRIPLLSTLTGRWATAEDI
TTAGYWARQVREPVRFHDAVVALAATGARVALELGPDAVLAGLGPHCVPDSDLDFLPTLR
RDRDEERALVTAVTAAHARGVPMDRAALLAGTGGVPVDLPTYPFQRRTYWLTAGDSSGIA
ALAGAVDSGDDAFDAGLPAMIAGQSPAQRHLTLVDMVRVHAAAVLGHPDVAAVPIDRPLQ
ELGFDSMAAVSLRRRLTAATGLTLPSTLAFDHPTCEAAARFLATRLAEEREPDEALATVV
RLETLLADTTPTAEVTARLEALLRTWNDRAATGGDGLSDEELFARLDREYGGV
>V4YYG7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii (strain ATCC 50861 / VEG)|TrEMBL
VWLFTGQGSQYVNMAKSLYETEESFRQTVKECSAYLATEKLLPTEGPSSLEDIIYPGQDA
DAEEAEHLLMQTQYSQVAIFVVELALTRVLKERGLRPAAVLGHSLGEYAAAVTAGVFSWR
DALRVVAVRARIMSEQDPQDGVMAACRLSAAEVQAALDSDLKNLKSVAVAADNGPRSVVV
SGRRSEVEEVLSFFSISGRARFLRVSHAFHSPLMAGAVEPVSRLFERVEFSEPAIPFIST
VLGRLAVGSELSDALYWSEQITKSVRFREAVVAAFGGAVAGLSAVEVGPKRTLANIGAAY
VNGATHPGCAWLCVIEGPATSESGSQFESFLKQVASLSSRKLHWNHRTFPLARLQEQKTE
DAGQNLRSMAKPSPHSQPSIWSEKWAYHSSVPENDAAFKVPKKAWIIVGVPSQHMAEVLL
SLKRMGLDTSRVCGLGAISSMETLQNLVQGGTWAGMLVVSGLWATVSAVESLTETAHILR
HYACLSTEIEVPVLAVVTRGAQRSVVSPETFGQRERPTLESVPQQNQVFGHLEDEVPVHA
GLLAFCRTLRLEMGRCCRRFKPFLYFDTDRLHPRQSKESLDYHLGAVLKWLSRNDVPASF
SEQIRPDSDTLREWDIVIRKQSYFVPRVAPVLLKQPSTTAAGRIQKAKSYIVTGGLGGIG
IVVASWLLRQGAGRIFLWSRRGVPTDDVKETNQWCELNAAMETGRIQTVSCDVSEIEQVR
HSIVLAVTDSILGGIFHCAGTEGKGKLQDVSQQDIADVNALQEALKIKLPASLLVEYACL
KDIIQFIMENCFSDAARSTSDLVPLVTREPAANDQGFAVVGMGCRIPKNATTTEEFWDML
LHEIDAVCEIPMDRFNIDAFYDPDPEQDKCYTREAALLDHPDFFDNTFFNLSDQEVLAID
PQQRVLLEVAYEALFEAGFTKEALLGKDFGVFCAAYNNDFQFTNLTQGKATMCVFDKGEG
RGRIPSLGEAAGYPEPGGFMCFIPNRISYSFGLTGPSIGIDAACASSLVAFDAAVTKLKR
GACSGALVGGVNIILSPTFFLGGCKAHQFSRAGRCKTFDCNADGLVRGEGCGAAFLLPLD
AARETGAFVHAVVRGSATCHYGRSSQITSPNTRALTRVLRLSLQDASTAPSLVRYYEAHG
TATVLGDVIEMSAVKDVFQTGRNAAAPLHMGTVHNNIGHLDAAAGIVAFLKTVLCLKHRF
VPANIHFKSLHPDIHGIDTQLIKYTRESHSIMTDDVATGVRKTIFGANLAYGMGGSVAAI
ITESGDEEADRRSLKAAPRHVWNHRRFPLNTQKFVYLMGAMGQISMDDMPTPQSDVIHVM
KRLSATALNVAFMRKLSPSTCAAGSIRSVFLTGATGFIGSQVLFHLLQVKRQDPKLGTED
KKLTIYCLVRARDRAHGIYRIRDSLVGRGIEWKHEFDQQVIPVIGNLEEGENMGLGPKQM
QYLEQTVDAVYHAADYVNFAAPYDALRKSNVLSLIPILKLCTTYVAKPLHLVSNFAHHLQ
YFAGFSEDLNIAVDETVSPPLSPASIDRLEQQMPAGIIGYPWTKWAVEEIIGRMKDVLHE
RCEEEGQRVSMEESEKNDILSKFQVTVYRLPNSCVYYNNGYTNFANASLSLVLASAQERM
IPPGVLPVGAPFLTTPVDLITGILVKLSMTERKRHHVYHLVSLRVARRKHVVQAIKWLFP
DSVECTADELFRRIDENKENSPAHPLRAAMRFWRRYWYSSDTDRDSPFPVAVNNVEDDLP
GVMATFPSLADTWLRMASYCVKNYHMVRHPFTLAISFERLKKAIAGITKQRIDELALPSQ
TQELLNETCSTEDTTDIAAVKALVEHANLRKYDDCAVSDVPDPRARA
>A0A4R8QWT7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides franklinii|TrEMBL
MQSADTPIESTPRFAIIGYAARFPGAADADEFWDVLREGRDAISEVPADRWDADEFFDPE
PGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGIAPTD
LAETNSGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPSVAV
DTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSHAHMLAPDGKCKTFDA
AADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGIAQQRVIA
DALKRAGVTPSEVGYLEAHGTGTSLGDPIEAQAAGAAYGIGREANDPLLIGSAKTNIGHL
EAAAGIAGVIKVILSLENELLPQHRNFENPSPHIPWDRLPVEIVKEATPWERNGRPRIAG
VSSFGFAGTNAHVILEEAPAATPESVDAPAVTGGRKYSILPLSARTPAALVQIADRYRNW
LSEHPEATLADLCLTAGVGRAHLEHRAALVVNSREAAVELLGAVADDRPAPGLGRGESHD
TPKTAWLFTGQGSQYPGMARELYDTEPVFAETVDRCAAAVADVLEKPLLDVIFDTDGPEA
EETLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVADVFSLEDGARL
IAERGRLFGSLPAGGRMAAVFTDAVRAESLTDEFPSLSVAAYNGANTVLSGPAQDLEKAV
ARLVADGIRCDFLETSHAFHSALLDPILDEFESYASQFNYKTPQRILIDNRTGTALGRSV
KLDGAYWRRHARQPVEFAKSVRTLADMNCKVLLEIGPQPVLTAAALRAWPDPATAPRAIA
SLRRNTADHRQITEAAADAYVLGYLPKFGAFQHGHAQKLDLPTYPFEHRQYWYRDNRDSP
NQQQNTSGPRTQAVRLLEDGKIEELANLLGGAGGDQQTLTVLTKLAAQHNQQRNTQSIAD
DRYQFRWEKSPTPLSGSEAAGSVTWLLVGDAAGAAQRLADVLSARGQQHQTLALPVSDAD
EAQLVEALRAAASGASEQGQTLRIVHVAALDGGKASSSTQSLLRIQHQILNGTRRLFRAA
AAAELRAPIWVVTQGAQRTTDTDTVAPEQTALWGFGRAAALELPQVWGGLADLSDASADE
WSQFISRVSVSGDAAAREDQIALRGQGVYVPRLVRREEAPSGKPLEVRSDATYLVTGGLG
SIGLEIAGYLAGRGAKHLVLTSRREPSESAQQRIDALGAQHGCDVRVVTADVADAHDVAR
LLAGVQAELPPLAGIVHAAGEIGTTPLSDLDGPSQQAELDRVFAGKVWGAWHLSEAAAGL
KLDFFINTSSIASVWGGYGQTAYSAANAFLDGLAWRLREQGIAGTSVNFGPWSAGMADAE
SRARLEQRGIKTLSPADALAGLADIVAASSSNGGAQGVVARIDWARFLPLYQQAGRRAFL
AELEREVPSHLAASATGTQSGTTQLVERLTNAPVQQRKKLLTDYLRDSVAEVTRVDVSEI
REDAGFFDLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLGDVLGLNEQA
KSAPQRTAATTRTDEPIAIVAVSCRFPGAPDPEAFWEVLSGGVDVIREVPEDRFDIDEFY
DPDPEVAGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYA
PAALRGSRTGIFAGVGANEYAHLLSSESIDKIEPYFITGNALNAISGRVAFAMGFEGPAV
AVDTACSSALVAVHQAVQALHSGDCDLALAGGVNVLLSPVTTIAASRARMLSPVGRCKTF
DSSADGYVRSEGCGILVLKRLSDAERDGDRVLAVIPGSAVNQDGASSGLTVPNGGAQQRL
IGTVLARAGLVGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGGSRDADRPLLMGSVKSNIG
HTESASGAAGLIKVVLSLQNGVLPQSLHFDNPSPHIPWESLPVRVVDKAIPWEAAGRPRR
AGVSSFGFTGTNAHVLIEEAPQPQAALLEGDADTTDVPESQAAQVGVLPLSARSPEALLA
VAQRYESWLTANPDVDLADVCLTAGRGRSHFEHRAALVVDSVQAAREGLAELVQNRLRPG
VVRGEHTNHPTTAWLFTGQGSQYPGMARELFDAEPVFAETVTRCAEAVKDIVDRPLLEVM
FATDRETGGEAGKVLRHTSFAQPAIFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVA
GVFSIEDGARLMAERGRLFGSLPAGGRMVAVFSDAKHVEQVAGEFPHVSVGAYNGPNTVL
SGPGEDLEQAVARFQEEGIRCTWLETSHAFHSELLDPVLDEFESYAGQVQFATPTLPLVC
NRTGAVLTAQTPIDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVW
PEHLAAPRAIVSLRKGVDDRRQIAEALGSAYVGGHRPNFAALQHRPRRTLELPTYPFQRR
RFWPKSSGSAIEGGGGASAGILGRGEDLASGDSVYISRLSVRSQPWLSDHVIYGTVVVPG
ATYAAMALAAVGTPARAKDVFFYEPIILPEKSSREVQLTLHPLEDGSGSTFQVHSRPYGE
RDVDWSLNAEGTVVTGIGEDAEPTSETAEPVEPVDAAIERMERMRPMELFEIFADLELAW
GPTWSGSLKSLWLGEGEAIGDVLVGEELAEQLGSEPMHPVLMDLCTGVAFPAFPALLAAE
QGVNDLFLPLRYGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYLDRDGRHLGGIRE
FTVKRAPREALLRGLGGDATRLLYTLGWHEVPVPPSEEHAAEASGTWLIAGFDELAAKVP
GCIPFDRTTDSELLGQVLEQAKGRGVPFSGVVWRAAGPSAQESTADAAARLETEIANLLS
AVHTVQNGSQNGVKLPDGLWIVTERAVATESGEPVDPVQASLWGFGRTTINEEPALRARL
VDGDGSPEAVQALVNLLVTPGHEPAEPEIAVRQGKLLASRLLPWSRTGHLTVPRGSDYVL
APTERGAIDNLRITEKEVPAPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAG
IVTQLGEGATGVEVGQRVYGSMQGAFGSRFNVPAQFLAPIPDGISGVEAATIPAAALTVR
LSFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQFGAEVFATASTFKRATLRKLGVKYVYD
SRTTDFADQILADTDGAGVDVVLNSLTSEGFIEATLRATGKNGRFAEIAKRDIWTAEQMA
QARPDIAYEIVALDTVMFQEPDRIRTLLTEVSEGLAKGEWTPLPAEIYPLTEARAAFRRM
QQARHIGKIVCQMPNPLAPRPDRTYLITGGLGAIGLHTAGYLAQLGAGDIVLTSRRAPDT
DAQRVIEEITERSKTRIHVFTADVGEESEVATLLERIRAELPPLAGVAHLAGVLDDALLG
QQSVERFRTALAPKAFGAEYLDRLTKGDELDFFIVSSSVSSLFGSPGQSNYATANALLDG
LIAQRRAQGLPATGINFGPWGQGGMASSEAATANISAQGLIPLDPSAALAALAEVIANGT
GQATILKANWQRAAKVLGSSRPPILDLVLPSAVGEVTGDSELLKQLMEIPVPQRAGFVTE
FLQREVQNFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTI
GGLAEYLVGQLPDAESEAAPQEAQPAAESAGAESDAAAPDATPEPSDAASEAKE
>K9V185|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Calothrix sp. PCC 6303|TrEMBL
MSIESNIENINESIEGIAIIGMSGRFPGANNVESFWQNLCNGVESLSFFSHAELVEAGVP
ASLLDNPNYVKAGGILEDIDLFDAGFFDINPKEAEVTDPQQRLFLESAWQALENAGYDST
KCDARIGVYAGASLNNYLSFDVHQDGLGSAESYQKLIGNDKDFLSTRVAYKLNLKGPSIT
VQTACSTSLVATILASQSLQSYQCDMALAGGVSIRVPQKTGFLHQQGGTLSPDGHCRAFD
ANAQGTTIGSGVGVVVLKRLSDAIADRDYIYAVIKGTAINNDGSGKVGFTAPSVDGQAEA
IAEAIALAEIEPETIQYIEAHGTGTSLGDPIEIAALTKVFRASTEKSGFCAIGSVKTNIG
HLDAAAGIAGLIKTSLALKHQLIPPSLNFRQPNPQIDFANSPFFVNTQLKDWKPTFTPRR
AGVSSLGMGGTNAHVVLEEAPIFTDSSPSRGWQLLLLSAKSASALEAATKNLTQYLKLNP
HANLADVAYTLQLGRRDFAHRRILVCSDTEDAIQELSTPVSQRIFNQSQESRENPSLAFM
FPGQGSQYVDMGKELYTTEPLFRHHVEHCCSILMPHLGLDLQSLIYPSESEKNLAAEKLK
QTCFAQPAIFVIEYALAQLWISWGIVPQAMIGHSIGEYVAATVAGVFSLADALFLVANRG
KLMQQLPGGTMLSVQLSELEIKPLLTENISLAAVNTTSYCTVSGATEAIEELQRHLQEIG
VSCRRLHTSHAFHSPMMEPILETFRELVQTVTLNPPQIPFISNVSGTWISASEATNPNYW
ANHLRQPVHFCQGLTELLKTPGSVLLEVGAGRTLSTFARQQRQQELTVLTSLPHPQEQQS
EVAFILSNLGRLWMSGIQINRSGFYIREQRHRLPLPTYPFERQRYWLEPTVSPRLLEVNS
AQYIVQNRRYSIDLDTSSELEKPLQPSLSKRPNITDWFYLPVWKQSIPLEISHQQKETQQ
KLACLVFADKYEFADQFKQLLTQQGEDVITVEIGDEFCQLDRHRYVINPQRPEDYEVLLK
DLQKRDFQPNTICHYWSIAPNDILLKEESQLTENYQYFGFYSLLYLAQAIGKQDSFNPCK
LLVVTNNLYSVIGEEKLCPQKATILGACKVIPKEYGNINCSLVDLVIESVDSSISLKVLN
NLLAEIGKIQNNQIVAYRGSYRWLQSFEPVALDDNFGSKAKFKQGGVYLITGGLGGIGLV
LAEHLAKTVQAKLILIGRGGLPERCQWEQYQLTHGSEDRISRKIQKMRSLEESGMQFMVT
SADVTDSQQMQAVVNQALQKFGQINGVIHAAGVAGGGVTQLKTQEMVRNVLAAKVDGTLI
LDDICQQLNLDFFVVCSSKTAILGEFGQIDYCAANAFLDAFATSRTASSGLTISISWDTW
QEVGLAVETVLPDGLKQKREEMIKKGILPEEGIEVFNRVMGSNLPHVVISTQDLPSLIQQ
SNADKYLEDALQAGKLSSVNLSKAKHSRPNLGNTYVTPQTKVECILTDIWQEILGIDQIG
IHDNFFELGGNSINTIQIASNANKAGLKLTTQQFFQHQTIAELATNLALESIVKTQENLE
IQEVSDLHSNSIKSSLMQEKQAEDIYELTPVQKGMLFHCLYESELSLYFFQHIFNIQGNL
DLEAFTKAWQLVIDRHPILRTGFYWHEIENPLQIVYNQVQVPLDYYDWCDIDPATQKSQF
TSLILSDRQNNFDFAQPCLMRHTVIRLSHDSYQYVWSMNHIIIDGWGGSLVFQEFVEIYG
ALCQNQEICLTPTRPFRDYINWLQQQDISKAEVFWRQTLAGIEAPTPLTYIENINNDLSP
TPEIRYSEEIIQLSLKNTQALNAFATQHHLTLATIINGVWAILLSRYSCCDQVLYGCTVT
GRPPQMDGVESMVGMFVNTLPIHVDVDGEQSLLSWLQRFQLQLVEARNYEYTPLTEAHKW
SEIPRNLPLFETIVVIENFPVSEFIKDWQGNIEFQHQEVYYRNNYPLNLVVYPNKELLIA
ISYDSRRFATDTIIAILKDVEIFLNDLVVNNDKQIKSLSFSTQRQQNITLTLEQELSALE
FI
>A0A086K5N9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii FOU|TrEMBL
SVRFREAVVAAFGGAVAGLSAVEVGPKRTLANIGAAYVNGATHPGCAWLCVIEGPATSES
GSQFESFLKQVASLSSRKLHWNHRTFPLARLQEQKTEDAGQNLRSMAKPSPHSQPSIWSE
KWAYHSSVPENDAVFKVPKKAWIIVGVPSQHMAEVLLSLKRMGLDTSRVCGLGAISSMET
LQNLVQGGTWAGMLVVSGLWATVSAVESLTETAHILRHYACLSTEIEVPVLAVVTRGAQR
SVVSPETFGQRERPTLESVPQQNQVFGHLEDEVPVHAGLLAFCRTLRLEMGRCCRRFKPF
LYFDTDRLHPRQSKESLDYHLGAVLKWLSRNDVPASFSEQIRPDSDTLREWDIVIRKQSY
FVPRVAPVLLKQPSTTAAGRIQKAKSYIVTGGLGGIGIVVASWLLRQGAGRIFLWSRRGV
PTDDVKETNQWCELNAAMETGRIQTVSCDVSEIEQVRHSIVLAVTDSILGGIFHCAGTEG
KGKLQDVSQQDIADVNALQEALKIKLPASLLVEYACLKDIIQFIMENCFSDAARSTSDLV
PLVTREPAANDQGFAVVGMGCRIPKNATTTEEFWDMLLHEIDAVCEIPMDRFNIDAFYDP
DPEQDKCYTREAALLDHPDFFDNTFFNLSDQEVLAIDPQQRVLLEVAYEALFEAGFTKEA
LLGKDFGVFCAAYNNDFQFTNLTQGKATMCVFDKGEGRGRIPSLGEAAGYPEPGGFMCFI
PNRISYSFGLTGPSIGIDAACASSLVAFDAAVTKLKRGACSGALVGGVNIILSPTFFLGG
CKAHQFSRAGRCKTFDCNADGLVRGEGCGAAFLLPLDAARETGAFVHAVVRGSATCHYGR
SSQITSPNTRALTRVLRLSLQDASTAPSLVRYYEAHGTATVLGDVIEMSAVKDVFQTGRN
AAAPLHMGTVHNNIGHLDAAAGIVAFLKTVLCLKHRFVPANIHFKSLHPDIHGIDTQLIK
YTRESHSIMTDDVATGVRKTIFGANLAYGMGGSVAAIITESGDEEADRRSLKAAPRHVWN
HRRFPLNTQKFVYLMGAMGQISMDDMPTPQSDVIHVMKRLSATALNVAFMRKLSPSTCAA
GSIRSVFLTGATGFIGSQVLFHLLQVKRQDPKLGTEDKKLTIYCLVRARDRAHGIYRIRD
SLVGRGIEWKHEFDQQVIPVIGNLEEGENMGLGPKQMQYLEQTVDAVYHAADYVNFAAPY
DALRKSNVLSLIPILKLCTTYVAKPLHLVSNFAHHLQYFAGFSEDLNIAVDETVSPPLSP
ASIDRLEQQMPAGIIGYPWTKWAVEEIIGRMKDVLHERCEEEGQRVSMEESEKNDILSKF
QVTVYRLPNSCVYYNNGYTNFANASLSLVLASAQERMIPPGVLPVGAPFLTTPVDLITGI
LVKLSMTEGKRHHVYHLVSLRVARRKHVVQAIKWLFPDSVECTADELFRRIDENKENSPA
HPLRAAMRFWRRYWYSSDTDRDSPFPVAVNNVEDDLPGVMATFPSLADTWLRMASYCVKN
YHMVRHPFTLAISFERLKKAIAGITKQRIDELALPSQTQELLNETCSTEDTTDIAAVKAL
VEHANLRKYDDCAVSDVPDPRARA
>A0A1Y2MK04|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudonocardia autotrophica|TrEMBL
MRALLFDRSAETGLRVGETADPVPGPGEVLVRVRAASLNFGEVALAAGAVPAGMDRPPEE
TVLGSDAAGTVQQAATDGSGPPVGTPVVTFGLVGAVAELRAVPVVLLGVVPSGVDLGAAS
TLPVAGLTALRALRRIGPLLGRRILVTGASGGVGRFAVQLASRAGAHVVATTSDPAAHGD
ALRALGADEVLPGPGALSEPVDGVLDQVGGRVLVEAFRALREHGTLVAVGHSSGEGEAFG
FGDLFGNDGGHDRSVVTFFLGATGDFGPDLTWLAGQVGSGALDAEPAWRGGLDDAGDAVT
ALLGRTLHGKAVVDLG
>D3D0C0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. EUN1f|TrEMBL
METQERTRLLDYLRRVTTELHNTRARLERAESGLREPVAVVGIGCRYPGGVRSPRDLWRI
AAQGRDVVSEIPADRGWDLARLGSAQSGGSCPETGGFLDGVADFDAEFFGISPREAAAMD
PQQRLVLETVWEAVERAGTDPTSLRGTSTGVVLGVIHQGFDSRVTDAGAGGELAGYVLTG
STLSVASGRVAYTLGLEGPALTVDTACSSSLVALHLACQSLRRGECDLMLAGGALVMATP
TSFVEFSRQRALSPDGRCRAFGAAADGFGLGEGVGVLVLERLSDARRNNHQVLALIRGSA
VNQDGASNGLTAPSAPAQERVIRQALADAGLSPGDVDAVEAHGTGTALGDPIEAQALLAA
YGRDRPADQPLWLGSLKSNIGHAQAAAGVAGVIKMIMSMRSGVLAPTLHADPPSPHIDWA
GGPLALLTDSTPWPRHPDRPRRAGVSSFGISGTNAHLILEQAPESEPVITGDAPVPGGTP
APEVVPWLLSARSAAALRDQAARLADHLDTGVGASASPGAIAHALAVSRAPLEHRAVVLG
RDATELREGLDALAAGHPAPGLVTGSAVPGPGPGTGTGTGTGTGTTSLAGSGGAAGVVTS
RAGTVFVFPGQGTQWAGMAGGLLGVSEPFTRRIEQCAAALAPHTGWELLDVLRGRPEAPD
LNRVDVVQPALFAVMVALAEVWRAHGVTPDAVVGHSQGEIAAACVAGVLSLEDAARVVAC
RARALSALSGRGGMLSIAAPREDVERILAPWADELAVAAVNGPAATVVSGGSEALARLAA
ACDGRDVRNRLLPVDYASHSPQVEQIRARLLTDLAGLRPQSGEVPVYSTVTGQPCDGAEM
DAGYWFRNLRGLVDLHGATRRLLADGHDVFVEVSPHPVLTAGLAATGEAEGYEDQVVLAT
LWRDDGGPHRLARSLAEAHVSGVPVSWPPFVPAGSEPPVELPTYAFQHRRYWPAPQARRT
VPDTARPSRAPRSRRDDVFWSVVESGDAEAFAELLGEEEPGALEPLGGTGAVDEAGSQRL
AETLAVIAGWRRRADDRAVVDGWRYRVVWESHTVPTAPPPAAPPRAGRRTGTGTWLLVTA
AATAATAAATAGLEGADGDSLAGWCERALAGAGAEVVRLPVAVGSADQRDLVRALGEACA
AAPVGVVSLLAADPAPVPVNGVPDGLGATSSLVRALGELGWAAPLWCLTRGAVTTGRLDR
PADPAQATIWGFGRVVALEQPRRWGGLVDLPEVPDERTAAQLRAVLAAAAAVRAGDAVRA
GDAVRAGDGADGDADGAGGRYEDQVALRPSGVLVRRLVRHPARGGWRPGPPPECALVTGG
TGALGRRVAEHLARRGVRRLVLASRAGTAAAGTGDLVERLRRLGAEARVVAVDLRDRAAV
TRLLEQAGPVDAVYHTAGAAAATEVGQLGPHDLAHAGAAKLGGAVALDDLFGADSGLTEF
VLFSSGAGVWGSGGQAAYAAANAGLDALAANRRARGLPATSVAWGLWDEEGMGGGETGRW
LRRHGMVAMDPARALLALDAALNDTCPDLVVADIDWSAFTAGFTATRQSTLLAAIEAELA
TGEQDVTHVADGHGGGLSGHGVGGRDGGGAGALAARLAALPVGEREPEVLDLVRALVADV
LGHRGTEAVPAARALRETGVDSLTAVEIRNRLSAATGLRLPTTLVFDHPTPRALAAHLTA
LVTGGPPVGGGPPVGGATGSSVDVPPGHGGDAGDEPIAIVAMGCRFPGEVETPDALWELI
TSGRDPMTEVPADRDWDSALAELRALRPDADAVVGGFLAGAGDFDAAFFGISPREAATID
PQQRLLLETSWEAVERAGVDPSSLRGTPTGVFVGLVSQDYGERLADAAEEYQGYRLTSGS
PAVAAGRVAYCLGLAGPAMTIDTACSSSLVALHLACQSLRRAECTLALAGGATVMATPTP
FVEFARQGGLSSDGRCHAFAASADGTGWGEGVGMVLLERLSDAVAHGHPVLAVIRGSAVN
QDGASNGLTAPHGPSQEAVIRAALADAQLGPADVDVVEAHGTATTLGDPIEAHALLATYG
QGRPPGHPLWLGTLKSNIGHTQAAAGVAGVIKMVLSLGRDVLPATRHVDAETPHVDWSAG
DVRLLTGPVPWPAHDRPRRAGVSAFGISGTNAHLILEQAPAIPEQAPGIPEQAPAGPDRP
AVVPLSGRGAAALRAQAARLGAHLTDRGDGPALADVAHTLAAGRAQLSHRAAVVAENHER
LLAGLAAVAAGGPPPVGAAGVARTEPVVAFLFTGQGSQRAGAGGGLYAAEPVFAQALDRV
CAAFAPHLDHPLHDLVLAAPGSSAAAALERTEYAQPALFALEVALHDLMTSRGVRPRHLI
GHSVGELTAAHVAGMLSLPDAARLVAARGRLMQALPATGAMAAIEASEDEIGLELAGREH
QVALAAVNGPSAVVVSGDADAVAEIVAGWAARGRRTRRLAVSHAFHSPHMDGMLTAFTRE
AAECTWSPPRVPIVSGVTGAPLEAVPPPEYWARHARAAVRFGDGVRWLAERGVTAYVELG
PDGVLTSMVDSCLDVLGSDPGGTGASGRGAAPLGSATPLRISALRPPWPEPRALAATLAA
LHVHGVPVDLSDVPAAGRRPVELPTYPFQRQRHWLPAGGRPGSRGRRAGERESAVTVGSD
VGGARRLDHPVLETATLIGASGGWLFTGRYSLAEHPWLADHAVQGTIVVPGLAFVELVLR
AGREVGAGGVEELTFQNPVVLGDVQAVRVQVWIDPPDAHGRRGVRVHTRPDPAGAEAEIW
TPNAVGVLASEAAAAGWPAVRGGGEADGEASWPPPGASPVDVDQLYGRLRERGYTFGPAF
RSMRAAWQRGDEWFTEVQLPDEHGGTADRYDIHPALLDSSGHVQLEAFGAGAGVGAAGGA
PGDAVPVLFAVAGVRVRTVGVPLLRARLTAAGADGIRLELADSVGRPAALVTSLTVRAIR
PDALRGAAGPLHALDWDPVGGAPAPGAVVAPAVAFAPDTGTFADDPELLRAAGHRLAGWA
WDRARRWLDDERHEGSRLAIVTSRACAVAVGDDPPDPAQAVVWGFLRAVQLEHPDRFVLV
DLDGDPASRALLPDALASGEPQLAVRAGRTLAPRLAPVPGAEAGPAPALAPQGTVLITGG
TGALGAALARHLVIRHGVRHLLLVSRRADRAPGVEALRAELAGLGATARLLGCDVTDRQQ
LAGALATVDPAHPLTGVVHAAGVVDDALLTGLTADQLRRVLAVKVDAAVHLDELTRGVEL
AEFTLFSSAAATIGSPGQAAYGAANAFLDALAARRRAAGRPVRSLAWGPWAAAGMAGALA
ESDLRRMRRLGAAPLRTDEGLALYDLARRVDRAVMVPIRLDDTALTGPLGRPAVLRGRPS
RAVTPVPARVDDGPGPISHTVPSPRSGAAPHPVSGVPSGVVAGPMGGARTDGSPGVGGGP
TAAGFGRLATLSPAQRLAAATDLVRGAVATVLGHDSSGAVDPDAPLLELGLTSLMAVELR
NHLTAVTGLRLPATLVFECPTADALARRLIADLPTVDPPAVAGESPQLQLEPL
>A0A0J6W599|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium chubuense|TrEMBL
MTDDPIAIVGMAVEAPGGVATPDHFWALLTERREALAPFPVDRGWPVHELIDASRRGGAT
PIHDLGGFLATAGTFDPEFFGISRREALAMDPQQRVGLRVAWRALEDAAINPDDLAGHDV
GCYVGASDMRYGPAMDEFGEHTGHLITGTSLGVISGRIAYTLGLAGPAMTVDTSCSSALS
AVHLAVQALRAGDCDLALAGGVCVMGSPGYFVEFARQHALSDDGHCRPYSAYASGTVWGE
GAGMFVLQRRSAARRDRRPVLGEVQASCVNSDGRSVGLTAPNQDAQTRLFRRALDTAAAD
IGMIGMIEGHGTGTRLGDRTELHSLAATYGAGAPGGGPLLGSVKSNVGHTQAAAGALGLA
KVLLAAEHGVVPATLHAEQPSDEIDWAATGLRLATEATPWPATGAARWGAVSAFGMSGTN
THIVVSVPDGEAA
>A0A0J6W731|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium chubuense|TrEMBL
MPFSGLPDGRLPVLLTAHDADLLPDAARDVLDYLGREAGQVAQIAAHLLGTRRVRRHRTV
LRARDTAELADGLRAVVDGRDHPLVARSARSTTSRRAFVFPGQGTQWPGMGAEAYRGLRV
YRDTADRIDAAFRSAGLTSPLRFLTAPAASESVSHLELQGAQFIHAVALAAVWRSCGILP
DLTIGHSLGEVAAAHVAECLSLDDAITVLAARAGAIEAIPGDHGVAVLGMDAVEAAELIA
RAPGWLELSAINASASVAVSGERRAVTALVEAVAGTGRFARPLAMSFPAHTSAMDACGRG
VTDALPVGEFTDSAVQFIGSATGDIVAAGTGLRSYWLANLRNTIRFDRAVDTGIAHHADA
FLEMSGHPSLLFAVEDGLDRSVPPRQALVLGSGHRDQPIADSLAANIAAAAVADPGFRWA
DLLAARPHRLRRFPGAPMRAEHLWAASTSPPAQPTLTVTGERWEPFALHDRGSATPRSVA
VLGAGPDHHPDPAWAEAIRRHRAAVPTAASEAEVLVVLAPSFPDVDAAASVGALSAALDR
GLLDYADAIGPRCRDVWLVTDGAEQINPDDAAPHLASAALAAMHRSVAHEHPDQSFHHLD
LASSRRAAAAAEILDVLLGATGEIAMRDGVCYRRTLDREASPAHRFDAEVLDDVVITGGH
GTIGSAYARALTALGARRITLLSRRGEVDDIAGGHGTEIVSRACDITDPAAVAAAARTAG
KATLVVHAAGTAAFAERTAITGTALTEMTAARLAGLDHLTATWPMTADTRILLCSSVTAV
WGGRGVAAYAAANRMLDAAAARLRIAGRRAVAIRWGLWEGSTIVDTTETARVQRTGLRPL
TPADAVAASLADHPIDPLIFAADPRRLQSFLAAAEKEPPPPVADGPVTASEAVRSQLALV
LDVDAATLDLGASLFDLGVDSLLALDLRRRLTRTTGHTVALASLLGGITGTDLIAALRRE
SESPA
>A0A0N0MWF6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MDAEPIALVGIGCTLPGQVHGTDDIHTVLREGRDCVEEIPLSRWDVNAFYDPDPLAPGKT
YTRHGGFVDDVDRFDAAFFGISDAEAVRMDPQQRLLLQTVWHALEHAGQNPDDLRGSNTG
VFLALMNSNSYFIVKHDAVGMTGITGYDAMSDAMSISAGRIAHFLDLRGPCFTVDTACSG
SLVALHLARQSILTGECDSAIVAGVNLILNPQVHIAFCKLGLFSPSGQCRAFDARADGYV
RSEGCVAVLLRRQSLAEERGDPVLASVVGTAINHDGHTPALTTPGRRTQEEVIRAVLTRT
GVDPAQVGYVEAHGTGTPVGDPIEMGAIVSTYGRSRTAGRPLYVGSAKSNFGHTEAAAGL
LGLVKAALSLHHETIYPSIHVDRLNPRIDLAGAPVEIPAEPVPWPRGATARLAAVNSYGY
SGTNAHAILREAPSPAPRADAAASRPAELLVLSAKSAASLDALADRWADHLARTDRESLP
QAVFTAAAGRAAHRHRLAVTGRSGIEIAGDLRLWRTRRTPPPPTSGHPAKRARTAFVFTG
QGVQYPGMARELYDSEAVFADAIDRCAEVLDGELPLALRRLLFDEQSPGALDDTRLAQPA
LFAVEYALAAQLRSWGVVPDAMAGHSVGEIVAACVAGALPLEDAARFTALRGRLMGELPR
DGVMLAVEADLETVRGWLAGREDDVSVAAVNGPRAVVVSGRAEAVDEVARLAGDHGSRTT
RLRTSHAFHSPLIEPILPELAKAAAGLRPQAPAVPVLSGVTGEALTGEEGPEYWSRQART
PVRFHDALRAMADRGVTVVVEIGPHPALRAHVPPEFTVIPTLLRDGRDVRNLLATAGALF
TAGAAVDLPALYRGPRHRRTSSAPRYPFRRDRYWVTPAPDTGQDQPTPAPAPAPAPAAPR
PAARTVHRHDIRPGTPWADHRILGSTVFPATGYLELAVNAYASADGHGSAPVELTDVDFV
RPLLLAPAKASGVDVVLEEDGARFRFTVGEGDGPARYCQGKVGPAARQGTSGNPPAELRA
ALPDQLAAGRLYGLLREDGLEYGASFSTVRELWLDGENGQALGRITAAPDGAARVGHDHR
LATMLDGCLHLTAAAAQAGTARGAYVPVGVRRMVLRGPLPDQVWGHVRLRPNDSGTALTA
QLRVLDDTGTVLADLTDVEFRRIASLTDTSAIPAPPAEGRPGDMRRELRERIGDRPEAAR
RQVVIDWLTDEITDTLGRMSSELEIDLHDLDPSLALLEIGLDSLNITELQRRIQEKLDFR
FKAMEALEYQSIDELAEYLLRRVILADS
>A0A073C9X5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Planktothrix agardhii NIVA-CYA 126/8|TrEMBL
MLTKWILCDRKSEFADSNKLHTELSPTKRALLALEQMQAKLEALENRHHEPIAIIGTGCR
FPGGVESPEQFWQLLRNGVDAIAPVPQDRWNIDEYYHPNPDIPGTICNRLGGFVGNLQDF
DAQFFRISPREAASLDPQQRLLLEVSWEALENAGLAVDRLVGNQTGVFVGICANDYWHRL
LSRQNTEIDAYLATGNSHSLAAGRISYSFGFTGPSLALDTACSSSLVAVHSACQSLRNQE
CNLAIAAGVNRILSPQMSINFSRAKMLSPEGRCKTFDQAADGFVRGEGCGVIVLKRLNDA
IASNDNILAIIRGSAVNHDGRTSGLTVPNGRAQQTVIQQALENGRVKPEQVSYIETHGTG
TPLGDPIEVNALNAVYGENRADHFPLIIASVKTNIGHLEAAAGMAGLIKVILALQHQEIP
PHLHFNTPNSHIDWDKIAVKVPTVFLPWVRGNQDRIAGVSSFGFSGTNAHVILAEAPLLE
TKSITTEPTVNLLTLSAKTPTALQQLAVRYQNYLKNNKNHALADICFTANIGRSQFNHRL
AIITRSKQELQQQFAEFCSGGTPEELFQGRVRENQVNHSFFPDLEFLPLQNDAKLLSNLA
EFYVNGGSVNWEKFYQGYSGCKVVLPNYPFQRQQFWI
>A0A073C9W9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Planktothrix agardhii NIVA-CYA 126/8|TrEMBL
MEVKPIAITGIGCRFPGTNNPQAFWKLLQDGIDMITEVPKSRWNNDEFYHPDATIPNKTN
SRWGGFLDQIDEFDPHFFGISPREALTLDPQHRLLMEVAWEALEDALQIPEQLAGSQTGV
FVGIGTHDYSVLLWQNPVSDSHATTGTANCIAANRLSYLFDFKGPSLAVDTACSSSLVAV
HLACQSLWRGESTLALAGGVNGLLMPTIMVGFSKSGLLSPDGRCKTFDASANGYVRSEGA
GMVVLKPLEQALADGDPIYAVIRGSAVNQDGHSNGLSAPDVEAQKALLRQAYKVAGVSPG
QVQYIEAHGTGTKVGDAVELQALGEVLAENRPVGEFCAIGSVKTNIGHSETAAGVAGLIK
AALILKYRQIPPSLHFQNPNPAVNFDQLPLRVQQQLTPWPNHSDPALVGVSSFGFGGTNA
HVVLQANVEMPQNVETPQNVETLHATSLQGLGTPHLLTISAKTQAALKDLAHRYEVFFRN
NSDSSLKDICHCANTRRSQFSHRLTIIADSHQQFQDRLNAFVHDQETSGVRYITTTPKTS
PKIAFLFTGQGSQYIRMGQKLYETNLIFRQTLDQCEQILRPYLKQSLLSVIFSETNDLHK
TAYTQPALFSLEYALAQFWISLGVKPSVVLGHSVGEYVAACLAGVFSLEDGLKLIATRGK
LMQVLPKNGGMVAVFADEETVRSLIKEDATIAAFNTPNTLVISGTLQNLSNIIEKCNSQG
IKTTPLNVSHGFHSPLMTPMLEEFRKIAAEITYHQPQIPLISNVTGKSINQDIATPEYWC
EHIIKPVRFTDSISTLKQLDTKIWLEIGPQLVLLGMARSCGSDLNQSLLPSLRPEQELQQ
FLSSLSELYLQGISINLAKLDPDYIPNLIQLPTYPFQRQSYWWSTAKFTPQKSPTVSPSL
HPLLGEKLQLAGTTEIRFQSRLSSQSPHYLQDHCLFSQPVLPATAYLEIILAAIKEIREN
VTLSQLTIEQPLKLSTAETTVQVILTPQSQGEYEFKIYSFIAGENIPLTETLHATGRLTQ
TNLKNRQLRGDFLLQEGGEIVSISDYYEQVKKQGLNYGKSFQAIAKLWQKEDQALGLIQL
PEGLRTETDSYTLHPVLLDACFQVLGAILLKKSDRTTYLPVSIENLYIYQQPSDKVWSSV
KIKTIHSQQITAQLQLFDDNKTLLAEIETLTLRAINRKSLQELIQISDSSSPELPDLYRL
TWKSKPRLSASQTRKTASWLIVSDCPEFGVKLAKSLEEKGDRCSIIHPENVSGKLQPCEQ
IIYLWSSDQTFDETGASLLDLVQRITQQPGITPPRLWIVTYSSPLSKQTKNYAFGLAKVI
RLEHPNLASICINFESFNLILPASQKALKPNDSLNQNFQTLLEELENPDEENQIVYRQGV
RYVPRLNAYQPDSKTQQSYQLKIANLGTLDHFDFVPLTRKKPGFGEVEIQVRAVGLNFRD
VLNGLGMLNQYLEQMGFSNASEIPLGGECSGTIVAVGTGVKHLKIGDEVIAAPALGSLGS
YITVNHQFVIPKPTHINFAEAATLSTAFLTAYYALIVQAQLKPGDRILIHAASGGVGQAA
IQIAQQMGAEIYATASPGKQEFLKSMGIKFVINSRTLAFADEIRELTNNQGVDVVLNSLN
GEFIPKSLEILSPNGRFIEIGKIGIWTQQKVQEKRADITYKAFDLLEIAEQNPQLINQML
TELMSGFEEKQLQPLPYTVFPVEEASNAFRYMAQAKHIGKVVITLHPPIQDITIREDSTY
LITGGLGALGLQVAQWLVTKQAKNILLVGRSEPSQHAKNVIEKLKNQGVTIQVIKADITD
LEAVEKVIKPYTISNQLPPLRGIIHAAGVLNDGILEKQTWERFREVLAPKVTGTWNLHTA
TLNLPLDFFVCFSSITALIGSPGQSNYVVANSIMDGLMEYRRLLGLPGLSINWGAWDEAG
MAAQLSNQNQGRLLAQGMKAIAPQQGLKVLDQLLSEPIPQIGVFSVDWSAFIEQVPDGVA
FPFLEDLISQDKARKPEVNANQKLDFLQQLATASTSDRKTILSEKIRSELATVLGYSSPE
SINLEDNLSDLGMDSLMAVEFKNRLQNCLGSTFSLSSVFDYPDLEALVDYFLTDVLTEEI
LNQSLKTRYIVTPTPPPKPLTPPPPTTKIIEEEIPAEYYQFERSPEYLTLERDVEKAEKL
GNPFFRIYDSVAREIIQVEGRELINYASYNYLGLCGDPQVSELAKTAIEDYGTSVSASRI
VAGERSLHQELEQEIAQFLGTEDCIVYIGGHATNVSTIGHLFGEKDLILYDALSHNSIRQ
GCLLSGSTAIEFPHNDWQSLEKLLQQKRRQFEKVLIVIEGIYSTEGDIAPLPEIVTLKKQ
YKTFLMVDEAHSIGVLGQQGRGISEYFKIPPSDVDLWMGTLSKSFASCGGYIAGSQQLIK
YLKYTAPGFVFSVGMSPPNTAAALAALRILQKEPQRVRHLCDRAQRFLTLAKQQGLNTGI
SQNSPIIPIIVGESQKAVTLSQALFKRGINVYPIVYPSVPYNGARLRFFMTATHTEDQIE
FTIKTLVEEIQK
>A0A1V2RCJ2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MLDVGDDQLQSVLPAVSEWRRRTRDRSTAASWLYQAVWEPLSGTSAARLEGTWLAVVPPD
GGTQTQGSAASAVIRALAAAGADVRTLTVDPATGDRAAITEALSQAVDEAQFSGVLSLLA
LEQRPHPAHLELSAGVAGSLLLVQAMVDLGARRSGARLWCVTQGAVTLDEPGENPAQAQV
WGIGQVAAVEHPEVWGGLVDLPGAEAAETVDDETRTDWLVRNLGAVLANEADEDQFALRP
TAVHVRRMARVPLNASDGAEEWRPRGTVLITGGTGAVEAHVARWLADRGAEHLVLTDATA
AEGAEATAESQRWAAEFGRLGVRVTVEACDPADRTRLAQTLKGLEAQGDTVRAVVHTAAM
VELTALAETGLPQLARAVAAKALPAQHLEDLLDQSSLDAVVYFSSVAGFWGSGDHAAYAA
ANAHLDALSQRQRARGQAAFSAAWAVWDVFEAREGDDPAVARALRHARGNGLPPLDPELA
LTALQQVMNRGPATVAVADVDWERFAPTFTLARPSRLIEGVPEARAVLVAAEESAQADGQ
ASGVLRERLADLSPEERRQELVTLVCTHAAAILGHGSGGTVEAQRTFRDLGVESMTAVEL
RNRLNQATGLSLPATLVFEYPTPSALAEHLNAELVQDGTTTVAALHAELDRMDTGLTRVV
ASETERLQITQRLESLLSKWNSTENSQSGTAETVAEKLESASDDEVFEFLKELGKPS
>A0A1V2RR50|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MEFERAIRTLGESGHGVFIESSPHPALIQAVSGTLEETFPVTVGTLRREKGGAERLLTSF
AEAWAQGVPVDWAGVLDDGRTVELPTYAFQRSRYWPEVPEARRAARSRDDWRYRIAWERV
GGDAAASLSGTWLLVGEAPEASAIADALAGCGAEVVAVAGPEELDVSVVAGASGVVSLLA
LDESPDAEYPWVPSGTAATVNLVRVLGQAGVQAPVWVVTRGAVQTGAGEATTSPAQAQVW
GLGRTVGLERPDFWGGLIDLPAELDAQTAARLTAVLADGREDQVALRESGVFVRRLVRAE
ARRAEAGKWAPRGTVLLTGGTGSIGPHIGSWLAGRGAPRVVLTSRSGPSASGVPGLAASL
ANAGSDVEVISCDLGAREQVSDLVRWIEESGPGLSTVLHSANRPYLARVEDTDREGLSVA
LGAKARGALHLDEATAALDLDEFVLFSSISATWGSNDHGAYAAGNAYLDALAEDRRARGL
RATSIAWGVWNSRDWDAVDATLDQGVGQVTPSLLRRQGMSFMDTGRALDTLGEILSEDET
FMAVADVEWQKFAPVFCAARPRPLLETIPEAREEFDPVGSVDAQAAARGEYVSKLAGLPL
DERRQTVIELVRSHAAAVLGYESVTDMPAERAFRDVGFDSLTAVELRNRLNTAAGVRLPS
TAVFDHPNPTALADYLLTELFGNELLSHSAMLGQFDRLAAGITPPDDAACDEIAAHLEAL
AQRFRTLRSDQGPAESAAGDAGKRKLQEATAEEMFALLEDELDDPGIN
>A8L4H6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. (strain EAN1pec)|TrEMBL
MSESGPPRRLADTPIAIVGMAGLFPHAHDFREFWQNIVDARDCIEDIPASRWNIDDYYDA
DPTVPDRTYSRRGGFVPDVAFDPLEFGLPPNQLEVTSTLQTLSLVVARDLLLDAGAHSAH
SADRADWYDADSTGVVLGVTGPVPLMHPLAARLTTPVLREVVRACGLTEDDAQAIATRYA
EAFAPWEENSFPGLLANVTAGRIANRLGLGGMNSTVDAACAASLSAVRMAIAELVDGRAD
MMIAGGADTENSIFGYMCFSKTQALSKSDRIRPFDEGADGTLIGEGIGMLALRRLADAER
DGNRIYAVIRGIGSASDGRSKSIYAPRAEGQERALRRAYADADCSPASVELFEAHATGTA
VGDRTELTALDAVLREAAGDEARFAAIGSVKSQIGHTKGAAGTASLMKLALSLYQKTLPP
TINVERPSGPLADDNTPLYVNTHTRPWVRDPRRPVRRAAASAMGFGGTNFHVVLEEHRAE
RPATGLLHRTARAWLWHAPDPAALRAALAAGEPPADGLISTDGLIPADHARVGFVTPAAN
PDGGATDGADLRRIALEQLAAAPDAEQWTHPAGVYYRRRALPDPRVGALFAGQGSQYLEM
GLDAALGVPTVAQALDDANAVFADDDARLAAVMYPPPVLDPQVRQEQESRLRATRYAQPA
IGALSAGQFRYLRELGLDCAGYLGHSFGELTALWAAGALDDTEFFRLARARGAAMAPPDP
ATGGNAGDGNAAGGDPGTMAAVQASREQITEILTDFPDVVVCNNNAPDQVVVGGGTQAVE
AVVEELARRGMTGRLLPVSAAFHTRYVAHAVERFAQDLAQARIGAPAAPVYANTAGAVYG
PDADANRAVLAGQLLAPVDFVAGVTAMRAAGCNIFVEFGPKQVLAQLTRRILDDAPVTVV
STDGGPLRDGDVVLKQAAVQLAVLGLPLADINRHAATAGAEGDAGQPRRAAMTVTLTGAE
YVPQSRRALYQAGLTDGFQVSAVAAAMNGGPASVATPPAAPAEPVPAPQPVLTAAPQPAL
AAAAPAAAELPAVPAVAGSPAAAGRPAGSAPVPATAALGAGPAGAGVSEAVALHLDLHGR
YLDGQLRVTEELVGLLRDGAQNGDQAGWVPAAVEQVRDQSLAAGRAHVHANEVLAALAGL
ELAAGGHAPAAPAAGAPARVGLAPRSTSAAGPAALAPPPAAPTVPAPVIADAPAMVPVGA
ADLVAVPAQPTGNGHHPPVPGGHPAGSPATGTPATGAPAAAGSGPDADSVRTALLDVVAD
RTGYPAEMIDTGMDLEADLGVDSIKRVQILGALQEHFPTLPSAGPETLAEMRTLNHITDY
VLTSLAAGAPPAASTPPNGTLNGSPAAAPGVDPDTVRTALLGVVADRTGYPAEMIDTGMD
LEADLGVDSIKRVQILGALQEHFPTLPSAGPETLAEMRTLNHITDYVLTSLGPVNPAPDG
APNGTTPKGDQPKGGEPTGTAGLNGHHAAGHGDDAVLPHRPVELVPAAPVDILDATPFGA
DPVAVLIDATGHDAPAPELTALADGLTARGFAVRTVRLPGHGGTAGESGTAGDGADQADP
LDGWDAAEVEQALAGALGGDGAVDLCALLIAANGGDGAWAAGIRRLADTVLVAKHAAGPL
SRAAARGGRAAFCAVTRLDGGLGLRGDVPAVERLVGGAAGVVKTLLREEPALFCRALDLH
PAHAPAAVAELVLTELWDAATDLAEVGLDATGARWTVRPGPFGDRAAQDHRAAQAEDREA
GTGAALPVLGPDDIIVVTGGARGVTADCVRALAARTRARFVLLGRTAADSDPEWATGVAD
GGLLAAAAAALAAQAGPGAPRPTPRQAEAARRDILARREIRDTLAALTAAGSDAEYLAVD
IADRDAVRAALEPYRGRAAALVHGAGALADSALTAKTPDAVRRVLTPKLTGLRNVLDALG
DGPGSPLRHLVLFASVAGLMGNPGQADYAAANEALGRLAAGWKHAERGRHVTAIDWGAWD
GGMVDADLRELFRSRGVALIDRTTGAEAFAEQFEPARVDDVCVLVGSAEALTGGSDVRPA
PALVARRELREIAEHPVIRDHQVGGFPVLPATFGLGWLVNVVERAHPGLTVVEARGFDVH
KGVVFDGTGELAFQVHTAAAEREGAGTSGRVVVKASVRSPGALPAGLSRYAATLVLAAAP
PAPAEVEDWPRLEAEWTAPGPEDGLEIYTGATLFHGPLLQGIRRIVARGDDRLVVECRLD
GAEVGRGAFAGALHDPVLADLLLHGPSVLGRWLTGQACLPLAVGRIDYRAPLPAGEPFAV
VIDGAAVRDTGVTSRVTAVGRDGRILVRLHDVAMVGTPDMAAKFAEGTASWHKKEVSA
>A0A378SZ56|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium senegalense|TrEMBL
MTGALPDARTAVLLSAHTEDLIGADAAAILNYVDSHPAVSAGDVAATLLTTRRLRRHRAV
VRAGDRDELTAGLRALTEDVEHPLVTRAQAGTAPGSSARIAFVFPGQGSQWPSMGVQAYD
RLPVYRTEVDKCAACFEAAGAASPLDYLLSDPDSGALTNDFSQVQIQGAQFVHGVALAAV
WRSCGVLPGITVGHSLGEIGAAYVAGGITLPEAVAVVIARATVLDRLTGPYRVAVLGVTP
DEASKVVAETQGWLELSVVNSRSSVAISGDTDAVAAAVATVAGRGSFAKEIEMWFPAHTT
ALDSARGELESMLPAAQFGESPVQFIGSATADVVKPGTGFADYWYTNLRSTVRFDRAIEA
AARRGARIFVELSAHPALLFAMGDLLDDADDLTGGPAVIVGSGRRDEPITERLSANIVSV
AMADAGYRWNDLPNHSAGRLRKFPFAPMRAEHLWATPQPLDPVPGLTVRVERWEQAPPPN
VPVGQRRVAVLDLASGQGPAAALHSALGEMPVATAARPGDADLLVVVAPVSEDIDPVVAA
ETLSRRIDDGLLNYPDAITADTREVWLITVGAEQVNSEESVRPGSAALAAVHRSLGYEHP
DQEFHHLDLPSAELNPAAAAAAVTAMLTAAEDIALRDNGSGPAVWRREMCDDTSDARTWT
ADSGIFDEVVITGGAGAVGLHFARQLAEQGARRIVLLSRSGLGDEQVSALSANGTEILAP
RCDLTDPAQIAATVAELGLSPASLVIHAAASAAIAPGRELTGADVRDTFAAKVNGLANLT
ATWPLRPDARIVLCSSVSGRWGGYGHAAYSAANRLLDTLGGQLRAEGKHCIAVRWGLWQG
DGIIDAAEVSRVERSGLRAMVPELAVEAGLRDYPSDPLVFTADAERLRTFLGGGREPAAA
VNHAPETPDSEAADAKGAMQIALGAVLKLTDTSALDLDTSLLDLGIDSLLAIDLRKKLKN
ATGRSVPLATILGGATAAELIEHLERPEKEAFSRD
>A0A2X4U0S4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Serratia plymuthica|TrEMBL
MKYPLTVGLALPLGGFNRKGSFFDRVSDFDAGYFGISPREAEYIDPQHRLLLETVQQALT
DAGLQASALRGSDTAVFIGISASDYALVSGDRVSAYSGLGNAHSIAANRISYLYDFKGPS
VRH
>A0A3E2N0H3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium marinum|TrEMBL
MLDHSISAVLRERASLRPSETAFTFIDYERDWAGIAETLTWSQLHRRTCNVARELKACGA
TGDRAVVLAPQGLDYIVAFLGALQAGQIAVPLSAPLGGASDERVGSVLRDALPSAILTTS
PIAGDVAECITLTPGKRAPSVIEIDLLDPDSGQGPAAESDSGSDIAYLQYTSGSTRTPAG
VVVSHRNLLANVEQGMSAYFGDHGRAAPPDTTVVSWLPFFHDMGLMFGIIMPLLEGFHSV
LTSPISFLQRPARWMQLLASNCQVFSAAPNIAFELAARKTSDDDLAGLDLGGVRNILSGA
ERVQPATLARFAQRFARFHLHPRALRPSYGLAEATVFVATREWGQPPVTVYFDSDELTAG
HAKRCATGTGTALISYGAAQSPTVRIVDPQTATECPAGVVGEIWVHGDNVAAGYWHRPQE
TERTFGATLVGPSPGTPPGPWLRTGDLGAFSEGELFIIGRIKDLLIIYGRNHSPDDIEAT
IQEVTRGRCVAIAVPDDGGVEKLVVIVEFKTRETSHEATMHRMGVVRRDVIAAISKTHGL
NVADLVLVPPGSIPLTTSGKVRRRECLQRYLHDEFTRLDGQLREPGPRVADAAAADADAG
ADSGLVQRLRLLRHQQHDLLVGVVCAQAATVLDYPSPNDIDPEWAFQDLGFDSVKATELL
DRLQTVTELTLPPTLAFDYPTPAALATHLGQLLSGSVAVAAPVQPRVSTDEPVAVVGMAC
RFPGGVDSAAALWDLVAGGTEAVGEFPADRGWNLAELFDPDPDAVGKTYARAGSFVADVA
GFDAEFFGISAREAQTMDPQQRLLLEVCWEALEIAQIDPAALLRSKTGVFVGAWSQQYGG
GSEGAEGYGLTGLSTSVASGRVAYALGLQGPAITIDTACSSSLVAAHLACQSLHTGESTL
ALAGGVTVMTTPAVFTEFARQRGLAADGRCKAFSAAADGTGWGEGAAVLVLERLGDANRN
GHPVLAVIAGSAINQDGASNGLTAPSGPAQQRVITQAVANAGVGLDEVDAVEAHGTGTTL
GDPIEAGALIATYGAAHHPDHPLWLGSIKSNIGHTQAAAGVAGLIKMIAALNHDSLPPTL
NVDRPSPHVDWSAGTVRVLTEPVPWPVTDHPRTAAVSSFGISGTNAHLILQQAPTPSSGS
PEPAGRPQHGAELGLPMWPVSARTPAGLAAQAERLHQHLLRHRDLDLTDVGYSLGCTRTH
HPHRAVVTVPAASPDPRAELLVALQALAAGDPHPQLVQHHLRSTSAGKTVFVFPGQGGQY
PGMAAELYRRHQVFSRVLDECDQALFGWTGWSVGAVVRGEPSAMALERVDVVQPVLFAVM
VSLARTLISYGIEPDAVIGHSQGEIAAAYVAGVFTLEQAAKIVALRSAALADLSGTGGMA
SVLLGADEVAARLQPYGDALTVAAVNGPTHTIISGDPPAIEAFVAAGEADGIQIRSITVD
YASHCGQVEPARERLLGELAGLTPAPGRIALYSTVHGVTSDQPLDTTTMTADYWYANLRQ
PVRFYDSIKVLLAAVEQVFVEISPHPVLAPAITDTLAASNGRRPGSVVIPTLHRERPDLD
ALTTTLARLQVHGRSPAWPVVYPHARPVPLPTYPFQHHRYWLTTGPGNDAAGLGLDRVGH
PLLGAITALADRDEVIATGRLALGVQGWLGAHRVGDVVVLPGTAFVDMALAVGDYVGCPA
VAELVLHAPLVLAEDTPTDIQIGVAGADGGARRAFNVHARTGTGHRGETGWVLHASGILA
AEPAAAGQPPMAALPVTEFDVADFYQRLADRGLHYGPPFCSVLGIGHEPADPDHIYAEVA
LPAGTDITGYGIHPALLDAALHPMAAALGAGADSESAAVRLPFVLSGVTLHATAATRLQV
WLTRSSADTFTLYASDPAGAPVISIDTIVVRALPDLATLTPPTTATSSGRGLWELAWPPL
SSAGAPGAAAVAEPPAWVVVAEDPDAVSAGLRNGVRRPDLDAVRPCPPVVIWSLSPPDLR
GDDDAVVSSMHSLTRHALAAVAAWLARPDTAETVLVVLTCRAVAINAYERAPNPAQAAVW
ALLHSAQSEHPGRIRLVDTDHAASSTDTLLQLLGSCTGTGGEPQLALRAGVAHMPRLAPA
RALTPPPTPHWRLITNGSGDLADLTLAPTPAPAELGPGQVRVQIRAAGLNSDDVAXASAA
TSHRDAGGEGRQDHQGLGVEAAGIVIDTAGDVDDFAPGDAVMGIFPNNAFAPTAATDHRA
VVAIPPGWSCPQAASVPVAFVTAYSSLIDIAALRAGQRVLIHSGAGAVGRAAIRIAQHLG
AEVFATADPAEQHILRGLGIPEDHIASSRARDFGDTLAAATGGRGMDVVLNDLRGDLVDA
SLRLLAAPGCFVEIARRDIREATDVAQTHPGLRYVVYDISTATPERLQRTWAAVSELINA
AVIEPPPVTAYGLLRARQAFRDISEARPTGKIVLIAPAALDPAGTVLITGGTGMLGGLFA
EHLLTHYGVRRLLLTSRRGPSGVGAAELAERLNGLGAQVTISACDCADPAQLAALIDSIP
TAHPLTAVIHAAGVLDDAVTSQLTAQQLDTVLAAKADSAWHLHQLTANTELAAFVLFSSA
AGVLGAPGQANYAAANAVLDALARERGPGATSLAWGYWQPSSGMTGHLDARDQARLTRSG
MVPITTSAGLALFDAALGVQHPNLIPAPLSTRALAALARESSLPPIFSALISTRPQAAMA
DSRALGARLAGLTPEQQHAMLTKLVLTATAAVLAHPDPAAMDPDQPFKDLGIDSLSALEL
RGALSAQSGVDVPATLIFDHPSPASVAVHLADLLSVAAVPAAAAAQVGKRAAEPADDRLA
YLDQAAFLGLRAGYGSLIQMIWIYDRAVDVEGLRRFHRNLGCGLLGRRIERSPLPFARDR
WVSAPVSQQIDFATTPRRRADVGAWADERARLPIDPEWGPGWHLGVVGLDDGGTAVSLVA
SHTIADAIAFGQAVVNAAEGRTQDLGYPAAGSRILRRALREDLRQTVNELPKIAHAFGGV
VRRLRRDRQELQSSIKAAPPPPRMAGGDHSVEVPAVTAYIDLADWDACAKRLGAKSNSLV
GGVACRLAARVGRVQGDGTVTLRIVVSLRTKDDTRGNALTAVDVAVDPAHAATDLREMHA
KITRAILEGMEDLDNEFLAPLPLAAITPRWVARRLVGMAAGGPTLPVTCSNVGDVPPAAN
RPDGTDADFAYIRLVEPDIAKSVLEGTGGRMLLASGRGRGKMCIGISAYLVGHSNTKDEL
REVVSRTFAEFGLNAEIDC
>A0A3E2YJ37|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MW-13|TrEMBL
MDTFLEVGPDAVLTAMVAEVAGDGEVRRVAVLRRDRSEVESLLAAVGQLHAAGVSVDWSA
YLAQAGVRPRVVDLPTYAFDRQRYWLADPEPATAPAAAGGPSDERFWAAVESGDLGVLGD
ELAVAAGESSAALLPKLARWRRDAQRRSAVDSWRYRVVWRTATLPAAGALTGTWLVLASP
GQEDHPAVAALAARGARAVPVVLDSVDRDAVARRLREAAGPDGRVDGVLSLLSLAATAEP
GVTPAAAEPGVTPAAAEPGVTPAAAAVSAALTVVQALTVAGVGGRVWWLTSGAVAVGGSE
AVENVDGAAVWGLGRVVGLEEPGLWGGLVDVPGVAEGWVWDRLCGVLVGGAEDQVAVRSS
GVFVRRLVRADVGSGAGTGVRLSGTVLVTGGTGGLGLRVAEWAAEVGAEHVVLVSRRGED
GLGTDGAGVVERLRGSSVRVSVVACDVADRAAMAALLTGLAGRGDRVRAVVHAAGVAQMS
PLGEVGKEELGEVLRAKVGGAVVLDELLAGAELDAFVVFSSIAGVWGSAGQAGYAAGNAF
VEGLVASRRARGLVGTSVAWGPWAEVGMAVGDVGEQLSRRGLVAMAPESAVVGLARALEV
GDVSVVVADVRWDRFASSFTALRPSPLLTEIPEAQPTPEDQPPGDAGGAPSALRERLAVA
SAAERERILLDLVRGTAATVLGHATPAAIRPGRGFLELGFDSLTAVELRNRLTAETGLGL
PATLIFDHPTPGALAEHLRAGLVPEQPALPIAAEVERLDQLLGEAADQVDEAVIGRLENM
LAKWRTRRPGGTAVPAPAETAGELDTASREELFDIIQREFGKS
>A0A2P7Z4N4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. 111WW2|TrEMBL
MPAAPRRAAADTGGTEGGPSLAERLGALPDEEQRVEALTDLVRVQVAAVLGHSDPGSVDP
GRAFQELGFDSLTAVELRNQLSTASGLRLPTTLVFDHPSPAALAAHLRQRITVEEGAAAT
PVLADLDRLKSAIRSASVDRDAFDRITGRLRELLDVADTANGSAAGDDDTDRDLDTASDE
ELFALLDDLG
>F4B0D4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Dokdonia sp. (strain 4H-3-7-5)|TrEMBL
MDTINSSLKKTPVAIIGLSAMFADAINVEQFWNNIISQKDSIVDVPASRWKIEDYYDADP
MVADKTYCKKGGFIPDVDFNPMEFGLPPNILEVTDASQLLALIAARDAFEDAGYGRESDK
FTALLKEKTGVILGVGGGQKLITPLTSRLQAPIWEAALRSSGISDTDIPHIVDKMKKAYI
GWNENSFPGMLGNVISGRITNRFDLGGINSVVDAACAASLSAVKMAVSELIEGRCDMMLT
GGVDTDNSPFMYMSFSKTPAFSRKGSIRPFDTDSDGMLIGEGVGMLVLKRLEDAERDGDR
IYGLLTGVGSSSDGRYKSVYAPRPQGQALAMQRAYDEAGYDASTVRLIEGHGTATGAGDA
AEFESMSMVFGKNNATKNNIGIGSVKSQVGHTKAAAGAAGMIKAALALYHKVLPGTINVT
KPHDKFGIENSPFYVNSETRPWFKNGVPRRAGLSAFGFGGVNVHFAMEEYEKKNSFTDRI
HQSFHSIYIKGANTEDLLTLLKNAHTSLNSKEGNTAFYNLKEISKEGTAEQSEARLGFVA
ESLVDCISKLEIAIKQLESNKNAWSHPRGVFFRPNGISSTTKVASLFSGQGSQYANMAKE
ATSSFERIQQTIADFDAKKGYDLANKIYPKPVFTEEDKAILEKNITNTEFAQPAIGAISL
GYYNVFKDAGFISDMVAGHSFGELTALCASGVISQDDYMTLAIARGNAMAGKNTSGDAGT
MLAVKASASEIEPLITAIPDVSIANINSSSQIVLGGTTEGITKAKTLLDSKNYRSILLPV
SAAFHTDCVGHAQKPFEKSIETIEFTSPTIPVYSNSTGNSYPTDPSEIKKILGQHILNSV
DFKSEIENMYAAGARVFVEFGPKSILTNLVKDILADKEHFVVTTNAKATKDSDLQIREAA
IQLQVLGCKLNAIDRNARQEKKPVTEPKVAVKIAGNNYVSPATQKAYKDVLNNGFKVSCA
TDIIKTEEDIKEIEVISEVINAVPTYTSEEDPTDQETEEDMMVDVIKSAIEGIKENQSKT
LDMFQTILMEQNKQTAQLLNLLSGNFAPDENILEAPTAPLSIDTPAPEAAVTKPIVTPIA
VQPSVEKNVATPTPSSVSETAAPATSNSEMLDLMLSVVADKTGYPAEMLELSMDMEADLG
IDSIKRVEIFGAITEQSDKLSNINPNDLTELRTLQEIVNYISAKAGISTTATPVSPTIKE
VVAAPVTVPVAQATPTAGNSEMLDLMLSVVADKTGYPAEMLELSMDMEADLGIDSIKRVE
IFGAITEQSDKLSDINPNDLTELRTLQEIVDYISAKAGIRTTATPVAQRAKEVVTAPVAA
PAAQTTTTTSSNSEMLDLMLSVVADKTGYPAEMLELSMDMEADLGIDSIKRVEIFGAITE
QSDKLSDINPNDLTELRTLQEIVDYISVKAGISTTAATVETAVTASPEVVGTDLFSTPIV
ETAAPNEGNSEMLDLMLSVVADKTGYPSEMLELSMDMEADLGIDSIKRVEIFGAITEQSD
KLSDINPNDLTELRTLQEIVDYISAKAGISSKKKSLSLA
>X8B7V9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium avium subsp. avium 2285|TrEMBL
MARSVSERQLRAAVSAAGPDRLFEVAWAPVTVPAAHGEPPVHQVFESLAAEGDPVGESYR
RTHEALAAVQSWLTEHDSGVLVVVTRGQWRWPARTSPTCPARRCGGWCARRRPSTPDGSC
>A0A2P8AM88|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MH33|TrEMBL
MDHPLLNAVADLPGDEGLLFTGRISLATHPWLADHAVLGTVLLPGTALVELASWSGRSVD
TAHVAELVLEAPLVVPPTGGVDLRVRVGPADGDGCRPVSVHSHPDEDGERSGTTRQWQRH
ATGLLAPTRAVTVAAGSAWPPADAEPIALDTLYPHLAGQGYHYGPVFQALRAAWRSGGDI
LAEVALDADAAAGPFSVHPALLDAALHALGASVLGRADSATASPGEAQPGLPFSWTGVAI
RPTRARELRVRLTSTEGSVAATVTDTGGVPVASLDALVLRPISSDQLDAARRAANRSLHR
LDWTAPEPGTQRTARIAVLGDADEWPGVEAYRDLDGLVAAVTGGTSRPDAVVATCVGQRA
DEPDPARAAHLVSHETLALAQDWLTREALAEARLVVVTRGAVCVDPGEQPADLPAATAWG
LVRSAQSENPGRFVLLDLDDDPRSVVAVPAALGTGEPQLAVRAGQLRVPRLVRLGPPPQD
RPEPKLSAGTVLVTGATGALGRLVARHLVTRHGVPRLLLVSRSGPDAPGATDLVDELTAL
GASAQVVAADVTDRAALAVLLDEIPADRPLVGVVHAAGILDDGVLPALTPARFDTVLGPK
VDAAWHLHELTEKLDLAAFVLFSSASGLFGGPGQANHAAANAFLDGLAHHRRARGLTVCS
MAWGPWANPDEPGGPQGHVDERRMSRAGFRPLGPDEGMELYSEALRHAEPMIAPVSLDHA
VLGRLGPALPRVLHGLVRPAGTAPAESPAGDTAAALRDTLAATPEAERDRVLSDLVRTHA
AAVLGYPSIRDIDEDRGFVELGFDSLTAVEFRNRLAAATGLRLPSTLIYDRPTTAAMVAH
LRGALLAERTTSALSVLGELNKLETAMRAIAADDADRAAVAGRLRELLSLWTYADSGPAD
AATGDGNLSSASAEELFHLLDDELGTA
>Q08MH4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Stigmatella aurantiaca (strain DW4/3-1)|TrEMBL
MGQAAAQSNRGERLSLRGISSLKPAQGTAVLERLLTGRATQAAVMQLDARQWLEFYPSAS
SPLWGQLLAERAKAKAEDPGAAQLREALRKAEPGRRLALLEEQLAKQMARVLRLDPSKLD
RMESFTNMGLDSLMSLELRNRLEATLGLKLSATLLFTYPNLAALADHLLGKLSSVDEAPA
KTAPTAAAPPPPPTLKPQAALPAELDQLGKDELLSLFDESLTESLKRTRMTRTSR
>A0A2K8RE11|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MDARQNTEIAVASSESKVVEALRASLMENERLESEVQSIRDSLTEPIAIVGMACRFPGGV
SSPEELWELIADGRSAVEAFPTNRGWDLENLYDPDLDRPGTTYVREGAFLHDAGEFDAGF
FGISQSETMVMDPQQRLMLETSWEAFERAGIDPAAMRGKNVGVFAGMAAGQEYGTAFHSI
PDELEGYVMTGGLASVLSGRVSYTFGFEGPAVTIDTACSSSLVALHMAAQSLRSGESSLA
LVGGTNVMATPTAFVLTARAGGLAKDGRCKAFAASADGTNWAEGVGVLLLERLSDAVRNG
REVLGVVRATAVNQDGASNGLAAPNGPSQQRVIRQALAAGGLSPADVDIVEAHGTGTALG
DPIEAQALLTTYGRNRAPGLPLWLGSVKSNLGHAGAAAGVAGVIKMVMAMRHGVLPRTLH
VDEPTPEVDWSAGAVELLTEAHEWPEVGRPRRAGVSGFGASGTNAHVILEQATEPTSGNL
PDEKARVLGDSVVPLVVSARGKAGLAGQAHRLGSFLTQRQEADLLDVGQSLVRSRGPLPD
RAVVLAADRDEALAGLDAVARAESAPGVVTGFAESTVGRTVLVFPGQGTQWAGMGAELLE
ASPVFAARMTECAEVLDPLTGWSLLDVVRQVEGARSLEDVDVLQPVSWALMVSLAALWEA
CGVVPDAVVGHSLGEIAAACYAGALSLPDAARLMVHRSRIAEAELVGRGGMASLTADVKA
VSILIEEWPGLEIAAVNGPASVVVTGELPSLEELLARCEADGIRARRIRGINGAAHSSQI
DVLHDSFLEALASVSAGPSRVPLYSTVTGRLHDTREFDVEHWFRNMRQTVQFDPAIRSLV
GDGHGVFIEVSAHPVLTSSVQDVLADLEAGPAVVTGTLRRDDGGPRRFLASLAHLYTHGV
RVDWEAVLGRGRERPVDLPTYAFQRQRYWLETAESRGDAPGLGLEVANHPLLGAVTEIPG
SDGVLFTSRLSLRTHPWLADHAGAGVVLLPGAAFVELAVRAADEVGYGLVGELVIERPLV
LPESGGVQVRVWVGEPDESGHRTVQVHSRREEAGSRGGWTRHVSGRLVPEDGQAEFDLTQ
WPPPGATAVDPDAFAHAYDHLAEAGYHYGPAFQGMRAAWTRGEEVFAEVSLPESAGKADE
YGLHPALLDAAMHTSLFRPDLSDESPKLALPFVWRDVRLHADGASTLRVHLTPLAPDTIR
LHLADTSGTPVASVDSLVLRPVVPELLRVGSGAAKDQMFRVAWEPISVRSVDDELKAVRV
TTAEDVRAAAATAPRVLLLDVAGDGRTDPDAARDLSGRVLEAVQAWLAEPAFQDTVLLAL
THSGAAVRDGDPAPDLAVATAAGLLRAAQSENVGRIILVDTDGTEASARRLPDVLAAGEP
QAALRSGSVAVPRLVRASPAEAQGRPLNPGGTVLITGGTGSLGRLAAGHLVTEHKIRSLL
LVSRQGPDAPGAAELEAELTELGANVRIVACDVSDRDSVAALLASVPHDAPLTGVIHAAG
VLDDGVVTSLTPERLDTVLRPKADAAQILDELTRDLDLAVFVLYSSIAGIFGSAGQSSYA
AANSFLDALAERRRACGLPATSLVWGWWGQVSGIVDKLAEVDLKRFDRLNMIEFTAQEGM
ELFDLALSDRSAALVLAKMDLKAMRDQTDSASVAPLLRGLVRVGRRVASDGASGAGGLAG
RLAEASPDQRGKILADLVQREVSAILGHLSPDQIGLDLSFFDLGFDSLTAVELANRLSAL
TGLRIPSTFAFDCPTVDLAVEALLESFELDVD
>A0A2K8RJF8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MTAPQDQVIAALRSALVDNERLKEANQRLSKRTDEPVAVVAMGCRYPGGVASPDDLWTLV
SEERDAISPFPEDRGWDTGGLFGEGGPDSLRSHTREGGFLTDAGAFDPGFFGISPREALA
MDPQQRLLLETTWETFEGAGIDPGTLRGSRTGVFVGLMGTDYGGPLHHVPDGVEAFLGMG
TQSSVGSGRISYAFGLEGPSVTVDTACSSSLVAIHLAAQSLRAGESTLALAGGATVLAGP
GLFVGLSQQGGVAADGRCKSFSEGADGAGFGEGVGVVLLERLSDARRNGHPVLAVVRGSA
VNQDGASNGLSAPNGPSQQRVIRQALANAGLKPSEVDVVEAHGTGTSLGDPIEAQAVLAT
YGQDRERPLWLGSLKSNIGHTQAAAGVAGVIKMVQAMRHGILPSTLHITRPSTHIDWSEG
DVRLLTEAVDWPEYGHPRRAGVSSFGVSGTNAHLVLEQPPEADEKPAAAAPAPGTAVPWL
LSARTADALRDQADRLRTHLAARPGLASADIAYSTATGRAALPHRAVVVGADRDAFGREL
ELLARGEFSDHTVRGTTAPAGKKVFVFPGQGAQWTGMAVELLESSPVFAARFAECERALT
PFVDWSLTDVVRSGAYDRVDVVQAALWAVMVSLAALWESAGVRPDAVVGHSQGEIAAAVV
AGALSLEDGARVVALRSKAITALAGRGGMVSVPLPVDEVRSLLPEGVSVAAVNGPSSVVV
AGDPAGLEIVLASVERAKRVPVDYASHSVHVEEIREELLSVLAAVSPRSAEIPFYSTVTG
GLLDTAALDAEYWYRNLRRTVELETVVRALGAAGHGVFVEVSPHPVLTSAIEETATGTVT
GTLRRNAGGWDRFLLSLAELHVAGVPVDWSAAFPTARRVELPTYAFQHKRYWLDPAIEHL
GGAADGHPLIGRPQPVADSGTLLHTGRLSLRTHPWLADHAVGGTVVLPGAALVETVLHAG
RDLGCGLLEELTVETPLVLDPVAPLTVQLSVEGSDPAGRRPFAVHSTSGEGPWTRHATGW
LAPAGAGDTAAEPVGAPWPPAGAEPVDIDDLYGTFAESGIAYGPAFQGLIAAWRLDGRIY
AEVALPEQQRSGLRRFGVHPALLDAALQTVGLTRDGDAGGPVLPFSFGGVALHGEPGGDL
RVETTVRGENEVSVRAADRDGRPVLTVDSLALRRLTGLARHDSLYQVAWVTRPLPRAVER
TDTVVRVEPGEPTATAAHETTRRTLARLQEWLAADHPDGARLAVVTRGAIATAADEDVTD
LAGSPVWGLLRSAQSENPGAFVLVDTDEESEHLLDAALSCDEPQLALRGGELRVPRLNRS
AHESSERELDRDGTVLVTGSADGLAGLVVRHLATEHGVRRIVLASRRGPGAEEIQRLGAD
LGAEIVGAACDMADRDALAELLASVPEQAPLTAVVHTAAVLSDGVLTSLTPEQVDTALRP
KVDAALNLHELTRDLGLREFVLFSSAAGVLGAPGQGNYAAANAFLDALAHHRRAQGLPAQ
SLAWGLWEHSSGLTQNLDEADVARISRGGVAPFDTKQGLAIMDLARGTDAPALVPATLTA
ATLEAVPEDAPALLRDLVRAPVRRSGAVPERRGADELRSSLAGLDEEDGEALLGEIVRGH
LATVLGHASADDIDETAAFLTLGLDSLTAVELRNRLTSVTGLRLRPTVAFDCSNPRELAR
FLRAELLAAPAVEPSAPPVSARRAGPLDAAGELFRYAAEQGRLKTGVKMLHQAAQLRPMF
TAVEGREGIPGPLRLATGAKRPRIICLSAFVALGGAHQFVRFASFFGQEYDVAALDVPGF
QNDEPLAADAEALADVYCDMISELVGDDPFVLLGSSSGGVLAHATGERMSRRGVAPAGVV
VIDGYPMTSPHINRVQDQLLKGMFEREERFVSLDGTRLTAMGWYCGMYEFWEPRAVDTPT
LLLRATVPLEGMTDDPESEEWRAVWPATKVLDVPGDHFTVMEDHLETTTRVIKDWLATL
>A0A5B7V4B5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MANEQKLREYLKRVTADLHQTRQRLQDAESVSREPIAIVAMSCRYPGGVAGPEDLWQLVA
EGGDAVSPFPDDRGWDADLHDPDPSRPGKSYAREGGFLHEAAEFDPAFFGISPREALAID
PQQRLLLEATWEAFERAGVDPLTVRGSRTGVFVGVMYGDYGNRILSNPRGLEEFEGYLGN
GSAGSIASGRVSYTFGLEGPAVTIDTACSSSLVALHLAAQALRQGECSLALAGGVTVMST
PDTFVEFSRQRGLAADGRCKAFAEAADGTGWGEGVGLLLLERLSDAQRNGHKILAVVRGS
AVNQDGASSGLTAPNGPAQQRVIRAALANAGLTAADVDAVEAHGTGTTLGDPIEAQALLA
TYGQDRPEGQPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMREGTLPRTLHVDRPNSLVDW
EAGAVELLTDERTWPEADRLRRAGVSSFGVSGTNAHVIVEQAPVEEPAEAVEPVAPVTAV
PWLVSGRSEEALRAQAERLHAHVTAHGGLDHVDIGWSLLSSRTAHEHRAVLFGRDRSQFL
TGLESLASGGPAAVTGSVVEGRLGVLFTGQGSQRIGMGRELYEAFPVFADALDEVCAHVD
PWIERSLQSVMFGADAELLEQTGYAQPALFAVEVALFRLAESFGVRPEIVGGHSIGELAA
AYVAGLWSLEDAAQLVAARGRLMQALPEGGAMLAVQAAEADVLPLLSDRVGVAAVNGPAQ
LVLSGDRAALEGLEQTLREQGRKVKWLKVSHAFHSPLMEPALADFREVAAKLTYQDPTLP
VVSNLTGALAEPAELKDPEYWVRHIREAVRFHDGLDALTGFGAATLLELGPDSVLTAMAH
DTVTDPAAQAGLVAALRKDRAESDTFLAALAQLHVRGIAVDWTPSYAPVESRRRVELPTY
AFQHQTLWLNPLTDGPVEAADPVDAGFWEAVEAEDLRALTGALEVDEETPFRSVLPALTA
WRRQRQERSELDRWRYRTAWKPLGRTAPGRLTGTWLVVAGAGAPEETWVDGAVQALEQGG
ARARVLRVGARDADRATLRELLSHALTDPGEGEGRGEPVAGVLSLLACAPVAAEAPKDGD
VPAGVLLTLALVQALGDERVDAPLWVATRGAVSTGASDRTADADAAAVWGLGRVAALELP
ERWGGLVDLPETADTRAVARLTQVLAAPAAEDQVAVRGSGVFARRLERAPLDAVAAGEWT
PEGSVLVTGGTGAIGGHVARWLASQGARHLVLTSRRGADAPGAAELRAELEGLGVEVTIA
ACDVADREALARLLAEIPESVPLTGVFHTAGVLDDGVLDGLTAERFATVFRPKVQAALNL
HELTRDSEHLTAFVLFASLTGTVGAPGQGNYAAANAFLDALAERRRAAGLPAVSLAWGPW
AGSGMAADDGSEERMRQAGLPVMDPARATEALRLATAQGGQAALVVADVVWDRFLDGFTA
ARHSTLFDDLPEVAALRAARPAGPAETAQPDLKRQLAALSRPDAERALLDLVRTHAATVL
GHGGVDAVPSDGAFKGLGFDSLTSVEFRNRLGAATGLTLPATLVFDHPSPHAVADYLSGL
LVGGDLSAAATEPAPTVRTDDEPIAIVSMSCRFPGGVRGPEDLWRLVADGVDALGEFPAG
RGWDTASLYDPDPATPGSTYARHGGFLPDAGEFDADFFGISPREALAMDPQQRLLLETSW
ELFERAGIDSAALRGSRTGVFAGTNGQDYLDLLKDAPDGTEGYIGTGNAASVVSGRLSYA
FGFEGPAMTVDTACSSALVALHLAAQALRQGECDLALAGGVTVMSTPSAFIEFSRQRGLA
ADGRCKAFADAADGTGWGEGVGLLLLERLSDARRNGHEVLAVVSGSAVNQDGASNGLTAP
NGPAQQRVIRAALANAGLKPGDVDAVEAHGTGTALGDPIEAQALLATYGQERPAERPLWL
GSIKSNIGHTQAAAGVAGVIKMVMALREGVLPPTLHVDRPSTHVDWASGAVELLTAARAW
PERDAEPRRGGVSSFGISGTNAHVIVEQPPLPDPEESAGAAEPVAPITAVPWLVSARSPE
ALRAQAERLRAHVADREELDPVDVGWSLLSGRAVHEHRAVLFGRERDEFLTGLDSLTSGG
PGAVSGAATGGRLGVVFTGQGSQRPGMGRELYEDFVVFADALDEVCAHIDPWIERSLQSV
MFGTDADLLERTGYAQPALFAMEVALYRLAESFGVRPEIVGGHSIGELAAAYVAGLWSLE
DAAQLVAARGRLMQALPEGGAMLAVQAAEADVLPLLSDRVGVAAVNGPAQLVLSGERVAL
EGLEQTLREQGRKVKWLKVSHAFHSPLMEPALADFRKVAESLEYREPSLPVVSNLTGELA
EPAELKDPEYWVRHIREAVRFHDGLKALQGQGVSTLLELGPDAVLTAMAHDTLTEPAAQA
GLVAAVRKDRPEPDTFLAALAQLHVRGIEVDWTLLYAPVESRRRVGLPTYAFQRRTYWPR
PTESGVPEAEAGAVDAEFWDVVRREDLDGLAGALDLDQEAPLKSVLPALATWHRRQQERH
EVDALRYGVTWTPLAGAAGPDAGTGLHGTWALLVPADAAGHPWRAAAEEALAEAGARVRA
VVVGDEAADRTALTRILRETGGPAAVEGVLSLLALDERPYRHPETDTPDPALTRGMAATL
ALAQAVVDAGTGGRLWVATSGAVSVGAADPLHAAAQSQVWGFGRVVALEHPEVWGGLIDL
PEATEANQAVDGPGSVRARLAALLSRAGAGDFTEDQLALRPSGVLVRRLTRAPGGPAGGA
GWQPRGTVLVTGGTGALGAHVARWLAGHGAARLVLTSRRGPDAPGAAELRAELEELGAEV
TVAACDVADRDAVARLLDAIPADAPLSAVVHAAGVGQDLMIAETGPRDFAAIVTAKTAGA
AHLDDLLGDTPLDAFVLFSSIAGVWGSGGQAAYAAANAFLDGLAERRAARGRPVTSIAWG
PWAGSGMAGDDEAAAHLRKRGLPVMRPDVAVAALRRALDGPGPQVTVADVDWERFAPAFT
VRRPSPLLDDLPEVRRALTAAPDATGGGAAEGDAATALRDRLAAAPPADRERIVLELVRT
EVAAVLGHTGTAAVREDRAFKEFGFDSLTAVELRTRLNTATGLSLPSTLVFDHPTPGELA
RELLAELLPDAAPGDADDAYAVHAADGAADHPADAEVRRALAAVPVARIREAGLLDALLR
LAAPDPAAAPATAAPDDDDADASIDAMDVANLIQMALDNSDS
>A0A5B7V304|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MTEEATVERNEGRDRALRRRLADAGDVERHRLLLDLIRTHAAAALERTDPAPLDAARAFG
AQGVRGRAAARLRERLGEATGVALSATALFDYPTPEALAAHLCSRVLGEPATGDADATAS
GAAVDEPIAIVGMGCRLPGEVRSPDDLWHLVRSGTDAISEFPRDRGWTVAHDPDPDHVGT
TVTRHAGFLYDAADFDADFFGISPGEAVTIDPQHRLLMETAWEAVERARIDPTSLRGSST
GVFVGIMYSEYGARIRHVPPSAEGYRVVGSMPSVASGRLAYALGLEGPAVTVDTACSSSL
VSLHLAAQSLRKGECRLALAGGVTVMATPWGYVEFSRQRGLAPDGRCRSFSADAAGSSWS
EGVGVLLLERLSDAVRNGHRVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIRQALAHAGL
TTADVDCVDAHGAGTQLGDPIEAQALLATYGRGRPAEQPLWLGSLKSNIGHTQAAAGVAG
VIKMVMAIRHGVLPRSLHISEPTPHVDWSSGAVRLLAGAEPWPATGRPRRAGVSSFGVGG
TNAHVIVEEADPEPDGTAPRTTDGADTPGRPLPWLVSGNGAPGLRAQARRLAEFLAPGPD
APDADLAYSLATTRAALADRAVVVAADRAEARTRLAALADATDATGGAYGGPGESTALGT
ATARDRVTFVFPGQGSQWPGMAAELMSTSPVFRASIEACAASLAPHVDWSLTKVLRGESG
APTLERVDVVQPALFAVMVSLAALWRSYGVEPAAVIGHSQGEIAAAHVVGALSLDDAARV
VAVRSRALRVLSGRGGMVSVVAPVDQVRRGLAPWSGAVSVAAVNGPRSVVISGDPTALDA
AMAAFERDGVRVRRIPVDYASHSAQVEEIRDTLVEALSGIRPRPAAVPFHSTVTGEPLDT
TALDATYWVNNLRDTVQFHRTVTRLLAAGHTTYVEMSPHPVLTIGIQETADEAGAHDALT
VESLRRNEGGPARFLTAVAEAHAHGVAVDWTEAFRHAAPRPTDVPTYAFQRRRYWLEDAA
PPVADVAAAGLDGVDHPLLGAALPLADGSGGTLFTGSVSARTHPWLADHAVADVLVVPGT
ALVEAALHAGAQTGCDTLEELVLEAPLILPEQGVVRVQVSVAGPDAAGRRAVTLYSRAQD
AGADEPWTRHAGGTLTRAARPAAAPPAAWPPAGAEEAELDDCYRELAKAGLHYGAALQGL
RRCWRLGDELYVEAELPEAAGGTDRYGLHPALFDAALHAAALPGGPGAGGGDATTRLPFS
WTGVTLHATGAARLRARVRRTGPDALSLTATDPAGRPVVSVESLGMRPVTAEALRRAAAL
SDASLLRLEWRPEPLPAPRGPGAARWAWIGPYDAAADDALAARGITRTAHPDVAALSAGL
AAGDAPPDAVVLAEPATGPGTDLAAAAHRAVHRALAAVRDWAADDRLAHTRLTVLTRDAV
AAAPEASPDPALAAVWGLVRSAQAEYPDRISLLDLDGTAASLAALPAAVDSAEAQLAVRA
GTPLTPHLARVPAPAGPGDAPAWRTDGTVLVTGGLGTLGRILVRHLVVTHGVRRLTVVAR
SGTAGAAEFVAELRAAGAELHVVAGDAGDRDVLAGALAALPDDAPLTAVVHLAGVLDDGV
LAAQTPERVDRVLRPKADAAWHLHELTAGSGVPLVAFSSVSSALGPAGQAGYAAANAFVD
ALAARRHAGGAPGLALGWGLWGERSGLTGDLADTDVRRIARSGVKPLSSDQGLALFDLAR
ATGEPVVFPLRLDPAGLRGDTADEVSPLLRGLARTPVRRAAADAGAALGEDSLADRLGRL
AAPEQHELLLDLVRGHVAAVLGYDDPRTVGERRPFTDIGFDSLRALQLRNRLGGATGLRL
TATLVFDYPTPLALGRHLRTLLVPDADDGPETAPRPAAGSERPGADEAVLAQLGSASREE
VFDLIDDMLAE
>B8LX33|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MRSIAQEAKRLLVFGPQALSARGSDFRSLQLTVKQLSWIADTITDLPSIWKDFVKEFPKY
GVILGEDLLRHLIEWTKTGDLTLSANEHLPNIILSPLVVITHITEYLKYLDTATAKSSYG
SSIETLGFCIGFLSALAVSISKDTKDIERYGANAIRLAMIIGGIVDVQDVLDTEGPSKSL
ATAWNSAKAAEELKEILSRFPEAYVSVSYDDQRATITTAFKSTDALQARLRDAGIVANEI
GLFGRFHHQQYAEDVDPIINFISSRPLLLLPDASNLIYQTRSNSGTGLITSGKLHAHALR
TILLQHSNWYPTFKSITESQVKHQRIAVIVFGPEPCVPPSILREIKQNVIHASDIQPVSV
EPPSALLPQQFKDDDIAVVGMSLKVAGADDTDEFWDLLCSGKSQHREVPRNRIKFDNEWR
EVDPKRKYYGNFLNDHDVFDQKFFKKSAREAASTDPQQRILLHVAYQALEQAGYFTSPDQ
DKKIGCFIGECAADYADNVACHQPNAFTATGNLKSFIAGKVSHYFGWTGTGLTLDTACSS
SLVAVHLACKSILSGECNAALAGGVNMMNSALWFQNLAAASFLSPTGQCKPFDANADGYC
RGEAVGVVFLKKMSAAIANGDQIIGTISSTGVSQNQNCTPIFVPNAPSLSSLFENVIQNA
QIDPKKISIVEAHGTGTQVGDPAEYDSIRRVLGGANLRSKPLSLGSVKGLVGHTEASSGV
VSLIKTLLMIQNKTIPPQASYKSPNPHLNATPDDKMQIITKQTTWEDDYRAALINNYGAS
GSNASAVITEAPRLPKSATSSHELPVVDYPFHIFGKDDRAIRDYCAKLVKSLETKGVESL
SIANLSFNICRQSNPTLDRALVFTSRSVKQLIEKLDAFQTGDINFAGTVVQPKSRSVVLC
FGGQISTYVGLNREVYENVKVLATYLDQCDYVCRSLGCESIYPGIFQRSPIDDIVKLQAM
LFSIQYACGRSWIDSGIQPVAIVGHSFGELTSLCISGVLSLEDTLKMIVGRATIIKESWG
SEKGTMMAIEADQREVEKLLAETLAPCEEAGQRAPTIACLNGPRSFTIAGSSRAIDIASH
TISKNPAYSKFRYKKLNVTNAFHSTLVEPLMSDLEQVGQTLQFNSPSIHLERATEFYSER
LGPKYVADHMRNPVFFNHAVQRISKKYPDAIFVEAGSNSTITNMASRALGSPSGSHFQPI
HITTDNGFQLLVNSTVSLWKEGLIASFWAHSRLQTYEYSPMILPAYQFEKSRHWVEPVPP
PTSSKQDLYGHIEKPKGLWSFFDYKDEKKRAARFRINTETERYKELVSGHIIAQTAPICP
ATVEVDIAIEALISLYPDFSSSGLQPRICNVDNQSPICIDTSRSVWLDVDSQNVNPNSWS
WQIISDAETSKASTVHVTGQINFVSVDNAEWQLEFSRYERLIGHKRCVGLLNSDDADDII
QGRNIYRSFGEVVDYSAPYRGLQKLVGKGNESAGRVVKKFSGESWLDALLSDCFSQVGGI
WVNCMTEKDPGDMYIATGFEKWMRSPDVTGDYKRPSSWDVFAYHQELPSEHSYLTDMFIF
DSTNGKLTEVILGVHYHKVAKATMSKILARLSGLPIAPASSAAKPSADAGERSSPAESDT
SNSGSKDEKGKSGETQDIVTRTKGLLAEISGMGVEEISNNAQLADIGIDSLMGMELAREL
EGLFKCILPSDELMNVTDFAGLVQIIKSTLGIGDDEEGSDQEGSDSSGSDSSSTFTPSTP
ATTSLSDVEDNGNGNPTSKVQSNVYTGDLQLPSSTIIEAFEESRKLTDDFIVNYRCAGYM
DTILPRQTQLCVALTVEAFEQLGCPIRSAKAGDQLIRISHDPQHQRLTNYLYKMLEEEAR
LIDTDGSKITRTAIAPPSKSSDAILDQLLRDFPDHEWANKLTHFAGSRLADVLKGDCDGI
KLIFGSDEGRRLVTGLYGDSLLNKLANVQMQDIISRVASKIPTDQGPLKILELGAGTGGT
TKGMVALLAKLGMPVEYTFTDLSGSFVAAARKTFKEYPFMKYKVHDIEKPPVAELVGSQH
IIIASNAMHATHNLEISTANVRKALRPDGFLMMLEMTSPVFWVDLIFGLFEGWWLFDDGR
EHAIAHQTIWERIMRSAGYGHIDWTDGNSPELNIQRVIIALASGPQYGRQPVAPLPKPEN
QLQPAAGRKAAVDEYIRKYTEGFCLGQPIKGATSPSSYEKCVLITGATGSLGSHLLAHVT
ALPNVKTVVCLNRRSGNDANARQQKALEDRGILLDAASQSKLQVFQATTSKPMLGLENTD
YEELLGKVTHIVHNAWPMTGKRPLSGLESQFQVMRNLIDFARDISARRPEGAKVTLQLIS
SIAVVGHYPLWTGNVVVPEERMTLESVLPNGYGDAKFVCERMLDETLHKFPDQFRVMSVR
PGQIAGSKVTGYWNAMEHLSFLFKSSQTLNVLPDFDGDLCWTPVDDVAGTCSDLLISERQ
PYPVYHIDNPVRQPWREMIPLLAELLDIPSNNIVPFKEWVRRVRAFPGSVEWDNPAALLI
DFLDDNFLRMSCGGLLLGTTKSCEHSPTLAAVGPVSVEVTQKYIQSWKNSGFLH
>A0A8F8Y1C7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nonomuraea coxensis DSM 45129|TrEMBL
MNPLELVLRLLAEHTGKGGADPDTLFIDHGLGSHDAVALAAALTAATGVPLPNTVLYDHP
TPRALAAYLSEGERERRPAPDGGGGGARPEPVAIVGIGCRLPGAAPGPAGLWDLLVAGTD
AVGPVPAARAGGNTGWAEPGVGVGGFLPDVEAFDPAFFSLNAREAAAMDPQQRLLLEVAH
EALQDAGLRQADLAGSQTGVYVGISGTDHIAAAFPAGARPDGYTPTGAAHSIAANRVSYV
FDLHGPSMAIDTACSSSLVAIHQAVLALRTGQCDLALAGGVNAVLSPEVGRCFGAAGVLA
PDGRCKSFGADADGMGRSEGAVVLALRPLPDALAAGDRVYALILGGAVNSDGRTNGLMSP
SAPAQARLLRAACRAAGVEPGDVEYVEAHGSGTRLGDLMELRALAEVMGGPGRAEPLRVG
SVKSNLGHLEAAAGAAGLAKAALALHHGVLPGSLHADPPAADFPWDSAPVRVVTKPKPWA
GRLAGVSSFGFGGTNAHLVLQAPPPGRSPGRAPARHHLPLSAHTPAGLRELAARWRDLLA
GPGPDLAAACHTAAARRDHHAYRLAVSGADAAELSAALDRALTALVADPPVPVRGPGTAA
LVFTGGDARLADALRRAGLRPALVLGDARGEPAAAGYSGALTAADARAAASRRDDLLAAL
ASGSPAPLAGVRVRMAGRLAQALCRRLGPELAVSVVEGPRSCVISGPEAALERVRDALSR
AGVACAELGAVDVVHSAPAAALAGRLEAELAGLAPRAGRVPLVSTVTGGPVEGPELGPAH
WAAQLARPCLLGDALAYALSQGVRTFVEIGPGVLPARLRALDGAGEARAVRCAGSADLPG
ALLRLYELGHDPDWSVLNPAAGVTSVPLLPWSRDWSPLEATA
>G0PRM5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MTDQDKLFEYLKRVTGELKQTRERLLRYESGEHEPIAVVAMSCRLPGGVRSPEDLWRLVA
DGADAITAFPRDRGWPIDELYDPEPGRPGKTYAREGGFVEDVADFDAELFGISPREALSM
DPQQRLLLESAWELFERAGLDHTALRSSSTGVFVGAGFQGYGSHADSSDGYLLTGSTGSV
VSGRLAYVFGLEGPAVTVDTACSSSLVALHLAAQALRAGECSLAVAGGVTVMSTPGAFVE
FSRQRGMAPDGRCKPFAAAADGTGWGEGVGLLLLERLSDARRNGHQVLAVVRGSAVNQDG
ASNGLTAPNGPSQQRVIQQALASAGLGPDQIDAVEAHGTGTTLGDPIEAQALLATYGQDR
PEGRPLWLGSVKSNIGHTQSAAGVAGVIKMVMAMRHGRLPETLYVDEPSPHVEWSAGDVR
LLTEPVAWSGEERPRRAGVSSFGVSGTNAHVILEEAPAVEPASEPTVAVPGPVPWLVSGR
GDAGLRGQAARLAEFVRGRDQDVDVAGVAAALVGRAVLENRAVVVGGNVVDLAARLDVLA
GGGLVDGVVCGSPVGGKSAVLFTGQGSQFAGMGVELYGRFGVFAGVVDEVCAVADGLLPE
PLRPVLFGEGGRGGLIDRTVFAQVGLVALEVGLWRVLVECGVRADVLVGHSVGEVSAAVA
SGVLSLADAVRLVCVRGRLMEEVPAGGVMVSVAAPEEVVRGRVVGVAGVWVAAVNAPGSV
VLAGEADAVRGVVDGLVAEGVRTRWLPVSHAFHTPLMDPVLEEFSREIAGLAFEAPRIPV
VSTVTGEVAGADFGSAAYWVEHARRPVRFADAVGVARGLGVRVWAEVGPQPALSAALDVR
EGEVVASFLRRDRDQATTLLTGLSRLHVHGVDVAWDQWVSRTGPLVEVPTYAFQRRRYWL
EGSARSVVGSDVDASTAEFWEAVERNDLGALGLDGDTPSDRVLPVLTEWRRGRREHHALA
GLRYHVTWQPVPEPAAPATLTGTWLVLTRPDDQAPEVIGAVGRAGGQAVRIAVPVDVTDE
ELSRRLIVVSGDTIAPSGVLSLLAVVDGAGAETGPEASPDRLPGTVTDTVTLLRALDAAG
VDAPLWSVTRGAVSTRDDEPTRDPAAALVWGMGRVAALEQPGRWGGLIDLPAVTDENTYD
LVCRVLAGTDREDQVAIRATGVLARRISRADGAAGTATTWRPRGTALITGGTGALGGHVA
RWLVGQGVEHVVLLGRRGSDAPQASALRDELTAAGARVTVAACDVADRDQLHEVVRKVRA
DGAEIRVVVHAAGLGLTGALSEVRPEEFRRTMAAKALGALHLDALFGRSDLDAFVLFSSI
AGIWGSGGQSAYAAANAFLDALARYRRGRGLTATSVAWGAWAGDGMAEGDAAVQLARRGI
TTMPVDRALSALRQILDRDETTATVADVDWSRFARTYLTVRDSRLFDEIAEAREAQAGEQ
ADDGKGAGDTPLTGRLRSLDEAAQDHALLDVVRTAAAEVLGHTGPTDIHEDRAFRDLGCD
SLTAVEVRDRLRAATGLRLPATLLFDHPTPRVLAAHLRTELFGAPTAAVPALPSPAGAPM
DGDPIAIVGMSCRYPGDVRSPEDLWRLVATGDDTLTDFPTNRGWDLSALFDDDPDRPGTS
YATTGSFLHDVDEFDAEFFGINPREALAMDPQQRLLLEVTWEALERAHIAPESLRASPTG
VFVGTNGQDYVSLLGGAGIAAEGYLATGNAASVVSGRLAYVFGLEGPAVTVDTACSSSLV
ALHMAAQSLRSGECSLAVAGGVTVMSTPGAFVEFSRQRGLAPDGRCKPFAAGADGTGWGE
GAGVLLLERLSAAVANGHRVLGVLRGSAVNQDGASNGLTAPNGPSQQRVIRQALSNAGLG
AGDVDVVEAHGTGTSLGDPIEAQALLATYGQGRAEGRPLWLGSVKSNIGHTQAAAGVAGV
IKMVMAMRHGELPVTLHVDEPSPHVDWSAGEVRLLTEPVPWRAEGRPRRAGVSSFGVSGT
NAHVILEEAPAVAPLPAPPANHSGPLPWLVSGRGDAGLRGQAARLAEFVRGSDQDVDVAG
VAAALMGRAVLENRAVVVGESVADLAAGLEALAGGGSVDGVVCGSPVSGKSAVLFTGQGS
QFAGMGAGLYGRFGVFAGVVDEVCAVADGLLPEPLRPVLFGEGGRGGLIDRTVFAQVGLV
ALEVGLWRVLVECGVRADVLVGHSVGEVSAAVASGVLSLADAVRLVCVRGRLMEEVPAGG
VMVSVAAPEEVVRERVAGVAGVWVAAVNAPGSVVLAGEEGAVRGVVDGLVAEGVRTRWLP
VSHAFHTPLMDPVLEEFSREIAGLSFEAPRIPVVSTVTGEVAGAGFGSAAYWVEHARRPV
RFADAVGVARGLGVRVWAEVGPQPALSAALDVREGEVVASFLRRDRDQATSLLTGLSRLH
VHGVDVAWDSWVPRGTDSVDLPTYAFQRRRYWPGGSVGASAGSLSGVGLSGADHRLLGAQ
VTVADGAAVFTGRLSVSTQPWLADHAVSGTVLLPGTAFVDFMAHAGRRVGSPQVGELTLQ
APLVLAADGPGVTVQVVVDVPDEHGRRTVAIYSRPDNDTGDWTRHGAGTLTEAPQPTDAT
EATETSDAPGASWDWPRAAAEMSGEDVYAGLSEAGFDYGPVFRGLKQVWQDGEDIYAEVA
LPDDPAGFVLHPALLDAALHALAAGSGTGPGEAGLPFAFTGVRVHRPGASTLRVRLRRQE
PDGVALEAVDTAGHLVASIDSLVFRPVSHADLAAPGAVDGDVLHLRWIPLLERAPGEAPG
EAPVEAPGTEPVRNPADVRQYGGHVHAVPDIVAASAAVRAGAAEPHWVVLPCRAPDEGTV
PERARALTVWVLGQVQAFLAAPEMAGRMLVVLTRGAVAADESDRGVDVSAAGVWGLVRSA
QSEHPDRLVLLDVDTEVGDDEWPAVLSALSAAPLPQLVRRSGTLSTPRLEAAGDGGDLTA
PPQGHWLLTPGSGGTSAELALVPRPSNADEPLGEGLVRVAVRAAGLNFRDVLISLGMYPG
AASIGGEGAGVVTEVGPGVTGTAVGDRVMGLLPDSFADTSAADARMVVRMPEDWTFQEAA
SVPIVFLTARYALGDLAGLCAGERVLVHAGAGGVGMAAVQLARHLGAEVFATAHPSKWGA
LRELGVAEDHVASSRDLGFRAAFLEVTGGAGVDVVLNSLAGEFVDASLELLPRGGRFIEM
GKTDVREAASLPPGVRYRTFDLTEPEPTRIGEMLSELLTLFRDGDLRLIPLTSWDVRRAP
AAFGHVRLARHTGKVVLNVPAPLDLDGTVLITGGTGTLGALVAEHLITAHGVRHLLLAGR
RGPQAPGAEELVERLRKYGADVRVVAADLAHRDQAVDVLAQVGTDHPLTGVVHAAGIVDD
GVLGSLTPDRVERVMAAKADAAWHLHELTRDADLAMFTLFSSASGVLGSPGQANYAAANT
FLDALAEHRRARGLAAQSLSWGLWARRSAISGHLADADLARVARSGMLPLGDEHGLRLMD
GARDRGGRAHAVPVLLAPGHRHTHPLLAHLGGPSLPARDATRGSGAGEPSVPIAERLRGL
SAEEQRRTLLTLVREQSAAALGHESTDAIGAHKPFKELGFDSLTGVEVRNRLGAVTGVTL
RATVVFDFPTPGALADHLWEALRPDDGTGEPPIIADLARLEAALTQAPDSGDLRDEITAR
LEEILWTWRDRAGGGQPVTEDGDEDLAAATDDEMFALIDEELGRQ
>A0A139Y017|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii ARI|TrEMBL
MAEVLLSLKRMGLDTSRVCGLGAISSMETLQNLVQGGTWAGMLVVSGLWATVSAVESLTE
TAHILRHYACLSTEIEVPVLAVVTRGAQRSVVSPETFGQRERPTLESVPQQNQVFGHLED
EVPVHAGLLAFCRTLRLEMGRCCRRFKPFLYFDTDRLHPRQSKESLDYRLGAVLKWLSRN
DVPASFSEQIRPDSDTLREWDIVIRKQSYFVPRVAPVLLKQPSTTAAGRIQKAKSYIVTG
GLGGIGIVVASWLLRQGAGRIFLWSRRGVPTDDVKETNQWCELNAAMETGRIQTVSCDVS
EIEQVRHSIVLAVTDSILGGIFHCAGTEGKGKLQDVSQQDIADVYASKVEGAWNLHRICS
EMSINTNLDFFVLFSSIAALPGNDAFATYAAANGCLDSLAEHRRSLSLPARSIQWGPWLD
AGMAARTPSFERFMRSRGIRGFHNEEAISHLETLLTADESLTCCAAVHVDWRIYAHIFGS
HVPTWLQDVVPGLQTSLTPFSESNVPEQMHGSMDIQGVESAVIDVARRLCGAEGIVSAST
EISSLGLDSLGAVEFRNALQEALKIKLPASLLVEYACLKDIIQFIMENCFSDAARSTSDL
VPLVTREPAANDQGFAVVGMGCRIPKNATTTEEFWDMLLHEIDAVCEIPMDRFNIDAFYD
PDPEQDKCYTREAALLDHPDFFDNTFFNLSDQEVLAIDPQQRVLLEVAYEALFEAGFTKE
ALLGKDFGVFCAAYNNDFQFTNLTQGKATMCVFDKGEGRGRIPSLGEAAGYPEPGGFMCF
IPNRISYSFGLTGPSIGIDAACASSLVAFDAAVTKLKRGACSGALVGGVNIILSPTFFLG
GCKAHQFSRAGRCKTFDCNADGLGVRYLPLRQKLSDHLSKHTSFDPRTTAFAARR
>A0A2X3KRN2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. Ea1.12|TrEMBL
MEVAAVNGPSATVVAGEPAGLDELLSVWEAEGVRVRRLPVDYASHTVQVDRVRDRLIAEL
AGIVPRVGTVEMWSTVTGSPVVSGQLDGEYWFRNLRSTVRLHEVADALVGEGHRVFVEIS
PHPVLTAAIIETAEAAGVPDAVVVGSLRRGDGGLDRLAAGAAQLWVRGVPVDWAPLVAGG
RQVDLPTYPFQNQRYWPDAPAVRGGAPDPGVRPADHPMLGGVVPLVDTGGLLLTGLLSRG
SQPWLADHAVGGAVLLPGAVFLELAVQAADQTGCDEVAELTLEAALVVPEHGGVHVQVAV
GPPDGAGRRSLAVYARPDGRGRPGDPEGPQEPWARHARGALAVRAPGGVAADPAFDLVVW
PPSGARPVPVDDLYPRLAAAGVDYGPAFHGVRAVWRRDAELFAEVGLPEPLRGTARRFAL
HPVLVDAAFQPLVLDPELGARRLRPFSWSAVRVLADGASTLRVRLSPAGADEVAVTLADG
TGQSVAEGTLALRPASPAPVVAPPGPPPAAAAPVPVIPARRAAADADQPDTSSFARRLTG
LAGPDREQALLELVRGQAAAVLGHEGATAVADDRAFRDLGFDSLSGVELRDRLTAVTGLR
LPAALVFNHPTPRALAGYLRAGLEPGRAGTAAALAELDRLEAALGMAAEGDRSVLTERLQ
ALLWRWADTPAAPAGGTYVPDGEDGDDFESMTDDEMLEVIDRELGAL
>A0A379BL27|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia brasiliensis|TrEMBL
MMRALEQTSLRGPRDMRAIADVPVPVPGPGEVLIRVDAAGVNFVDISRSYGTFRGGPQPP
YLAGFEAAGEVVALGPEVTAPVPGARVFGVGEAAFAEYMVLPAAAVQPVPPGWTAAEALG
LGVNWPTAIAALRPLGRLTAGETVLIQAAAGATGRAAVLLAKHYGATVIAAAAPDKHETV
RSCGADQVVDSHSADLAAQVRALTGGSGVDLVLESAGGAALEAGLGAARRVTGRVVVYGL
AGGTATLSNWDLVYRNQVHVIGLNMGVLIEAAPDIFGAVLAELSGLVAAGVCAPARPMVH
DLADGPKVLAALESRATVGKLALRPTLPA
>B2IXK1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MTSLNCATFVDLLSYRSLSQPNQIAYTFLVDGDTEEVKLTYQELDQKARAIAVELQSLKA
APGERALLLYPSGLEFIVAFFGCLYAGVLAVPVYPPRRNQRMTRLQAIVKDSEARFALTT
ASVLTNIQQGFAQEPELTALHCIAIDKIVSDASNWQKPPLEKSTLAFLQYTSGSTGTPKG
VIVTHGNLLQNSEYIKSAFELTPNSVSVTWLPSFHDMGLIDGVLQPLYTGFPSVMMSPAS
FVQQPIRWLKAISDYKATHCGGPNFGYELCVSKITPEQRANLDLSSWCSAYSGAEPVRRE
TLEKFAATFKSSGFQAKFFYPCYGMAEATLMISGGGVADEPVYCVVDPKALEKNQIIQVS
EDTPKVKHLVGCGYAWLDTKIAIANPQSLTLCAPEQVGEIWVSGSSIAKGYWNRPEQTKE
TFHAYLADTAEGPFLRTGDLGFLKDGQLFITGRLKDVVIIRGCNHYPQDIELTVEQSHQA
LKAGSGAAFSVDIDGEEQLVIVQEVERTYLRHLNLDEVVEAIKTSVSQIHELQVYAVLLL
KTGSIPKTSSGKIQRHACRAGFLAGTLNALNTVDVVIEPQLQNPKESKKMQFSLLYFSSN
EAEFSDEKYKLFLEGAKFADRNGFTAVWTPERHFHAFGGLYPNPSVLSAALTSLTKRIRL
RAGSVVLPLHNPIRVVEEWSVVDNLSHGRVDLAFARGWNPNDFVLSPDTHADSKEVMFSG
IQTVQKLWRGENISLPNGVGKQTDIKVYPLPMQRELSIWITCTGGKERFIEAGASGFNIL
TALLFQPVEELAQKIALYRETRKQHGYDPDSGQVTLMLHTFIGEDIKVVRNQVREPFIEY
MKSSVNLWRHGSDDLDKLTETEKANLLAYAFERYFHTSALFGTPSTCLEMVQRLHEIGVD
EIACLIDFGIDGNTVLASLDSLNNLRQLVNGVDEPSIKETIESYNQPKTDVLKQTNNAII
NNSLPAFSIETSLKIPSRQNEEVQVPQGSLLQWIGEVIVQQIANSLGKKSSQISLDKSFY
SFGIDSLKAVEIMETLGEKFGFSISPTLLFEYPTPTEFALYLIQEQKTQLQKYLLVNWEP
AKLWAVNLERQKAVVLSNKLFNPASTKVVEPINDRIRAEDIAVIGMSGRFPQSPDLQSFW
ELLSQGKNAIAQVPSLRWNLSDWYDKNPGAANKTYSCWGGFIDHIDQFDPLFFQISPREA
ELMDPQQRLFLEVAWEALENAGYSPESFAQSQVGVFVGCSNNGYYQRIAPALNTSDYSAG
IGNQNAIIANRVSFLLNLRGPSVLIDTMCSSSLVALHMACRSLQQGECTTALAGGVNLLL
SPEYYVGMSRMKMHSPNGRCATFDSQADGIVLGEGAGALLLKPLSQALKDGDRIYAVIKG
SAVNHDGRTNGITAPNSRSHAEVICQALDAAGISADTISYVEAHGTGTSLGDPIEVEGLT
KAFRKYTERKQFCKIGSVKTNIGHLECAAGMAQLLKVILAIQHRQIPANLHFQQPNPLIP
FAETPFQVNTKLCSWESSGLRRAGISSFGIGGTNAHIVIEEAPPLEPVIPEIERPKHLLT
FSAKTENALVQLVSRYETYLAANLDLPLGDICFTANTGRSHFQHRLSAIATSTSDLHQRL
LNFISQQEVTGIKIGRIHENTPPKIAFLFTGQCSQYVGMGSQLYETQPTFRKILDYCNEI
LRPYLKEDLLKVIYPQPGETSLIDQTAYAQPALFALEYALVQLWKSWGVEPSVVMGHSVG
EYVAACVAGVFSLEDGLKLIAERSRLMQSLPQTGAMVAVFACEADIWAITEIDLAEVAFA
PRLEEKPSVGIAAYNGPQNTVISGEREAIERICANLKAAGIQTKKLVTSYGFHSPLMEPI
LAEFRQVAATVTYNAPQIDIISNVTGQLIGEAINPEYWCDHLISSVQFAKSIQTLHTADY
EIFVEIGPKPILLGMGSKCLLGKGLWLASLRQGREDWQQILESLGELYVHGVQVEWSGFD
RDYFRRRVQLPTYPFQRKRYWIDAPVSTSDNKFDTQKSLPSQLSTSQFDTEIAPPLKALQ
PKVDTTPQIKRLDLIVSKLHSYIVNLLKAEPSEVDFYAPFLEIGADSLMLIDAINYIDIT
YRIKITISQLFEQLTTIYAVASYIDQNLLPEPIFVDVQLPEPVYQTQPPTPQSPPLAFVE
SNGNGHSHTQQPTLKSTVQQTAGETAVERIMLQQLQVMSQVMSQQLDVLRATGNVLSSNG
NSHLASSPPTPQNQVVKETGIAINQVQSNQTVTKNFSPIEPPPPREINQPQQQHLKTLIS
NYTQKTQSSKQYAQTYRSFLADSRAVAGFRPSTKEMVYPIIGERAKGARCWDIDGNEYVD
ITMGFGVLLFGHAAPFITAAVDEHLQQGIQIGPQANYAGEVAALISELTGMERVTFCNSG
TEAVMTALRLARTKTGRSKIAIFAGSYHGHFDGILAKESLDGLSTVPIAPGITANAVEDV
LVLDYGEPKSLEILQAHAAELAAVLVEPVQGRNPDLQPREFLQQLRQFTAVAGVALIFDE
VLVGFRIHLGGAQAWFGIEADIVTYGKIVGGSIPIGVVAGKASYMNGIDGGLWNYGDASY
PQVEKTFFAGTFNKNHLGMAVARAVLKYLKSQGPALQQHLNQRTSDLAIALNTYFEQEEV
PIKIVYFGSLFRFAFSGNFDLLFYHLIYKGVYIWEGRNCFLSTAHTDEDIEYVIQAVKHS
IEEMRAVGFIPKRSPKLSAGSNGNGTVKTTQNGVLTKPVVTESVPVLEAIAREGKLPLSL
AQQRLWFLDQLEPNSAFYNIPAAVRLQGQLNVAILEQSFREIIRRHEALRTNFITLDGQP
HQVIHPNLNWQISVVDLQHLPVSKRENESQKIAIAEAQRPFNLETESLVRATLLVLSQTE
YILQVTMHHIVSDGWSMSILIEEFTALYTAFSQGQPTPLVELPIQYVDFAVWQRKWLQGT
VLQSQLTYWKKQLSGAATILSLPTDRPRPTMQTVRGAHQPFALSFELTEALKALSKKEGV
TLFMTVLAAYNILLYRYTGQADILVGSPNASRNRPEIQGLIGYFLNILLLRADMSGNPSL
REFLKQVRKTALGAYAHQDVPVEELIEALQPVRDLSYTPLFQVMFILDSATPISEMQLPG
VTWSSMTVENYTSKLDLTLTLENTAQGLVGEWEYNTDLFEAATITRMAEHFRNLLEGMVA
NPEQRIAELPLLAAWERQQLLVEWNNTQREYPHKCIHQLFEEQVELTPNAVAVVFGNQRL
TYQELNSRANQLAHYLQELEIKPDTLIGICLERSLDIFVGILGILKTGAAYVPLDPDYPQ
ERLDYMFSDSQVSILLTAKKLVTQIPRHSAQLVYLDADWDVIATKSQQNLASEVKPENLA
YVIYTSGSTGRPKGVMVPHRSLVNAYFGWEQAYELRTKTSSHLQMANFSFDVFTGDLVRG
LCSGAKLVLCPREWLLTPELLYKLMQEEKVDCAEFVPAVIRNLIAYLEKTKQNLDFMRVL
AVGSDSWYVKEYEEFQRFCGLETRLINSYGVSEATIDSCYFESTNVKLPVEALVPIGKPF
PNVQIYILDSDLQPVPIGVLGELYIGGAGLAHGYLNRPDLTQERFIANPLSNEPTSRLYK
TGDLARFLADGNIEFLGRIDNQVKIRGFRIELAEIEAVLRQYPTVSQTVAMAREDIPGDK
RLIAYVVGNQESVPVISDLRRFLKEKLPEYMIPAAFMVLQTIPLTPNGKVNYRELPAPEI
SRAGLEASFIAPRNPIEEILAQIWVDVLGVKQVGIHDNFFELGGHSLIATQLISRIRTAL
KVELPLRSLFEASTVADLAERIALQQDAPHLNAPSLQSVVRDGQLSLSFAQQRLWFLNQL
EPNSALYNIAGTARLQGELNVIALEQSLGEIIRRHESLRTNFITQEDGQAVQIIRPDAAF
TMPVVDLRQLSASEQEIEIQRLATVEAQQAFDLANQLLIRATLLVLSKTEHILLFCMHHI
VSDGWSMGVFVQETAAIYGAFSQGQPTPLPELAIQYVDFAVWQRQLLQGEIKESQLAYWQ
QHLAGATALLELPTDRPRPAVQTFRGANQSFVLSFELTGSLILLSRQEGVTLFMMLLAAY
DTLLYRYTGQTDILVGSAIANRNHNEIEGLIGFFVNTLVFRTDVAGNPSFRELLNRVREV
ALGAYSHQDLPFELLVETLQPERNLSYTPLFQVAFVLQNAPMSEIELPGLTLSSMTPDNK
TAKFDLTLTLENTATGLMGVWEYNTDLFEASTIERMTGHFQTLLESVVIQPEQRIGELPL
LTAKEQYQLLEEWNHTQKDYLGNICIHQFFEMQVERTPDAVALVFENQQLTYRELNQQAN
HLAHYLRTLGIRVDVLVGLCVERSLEMLVGLLGILKAGGAYVPIDPEYPQERISHILSDS
QVSLLLTQHRLVARLPEHQATLVVIDESWEQIIQHSQENPISGVKDSDLVNVIYTSGSTG
KPKGVMVKHSGLCNLAQAQIDLFDLLPSSRILQFASFSFDASIWEVVMALGSGARLYLGT
KESLLPGLELIELLRDYGITHITLPPSALAVLPQAELPALQNIIVAGEACAPDLIKQWSV
GRRFFNAYGPTETTVCATVAECGNGERSDKPPIGRPIPNTQAYILDSYLQPVPIGVPGEL
HIGGAGVAQGYLNRPELTTEKFILNPFEDSAALASPRASAEGSRLYKTGDLARYLPDGNI
EYLGRIDNQVKVRGFRIELGEIEVILSQHPAALQVAVIAREDVPGDKRLVAYLVLNQEEA
PTVNDLRQFLKQKLPNYMMPSAFVFLETLPITPNGKVDRRALPTPDLRCELEVSFVAPTT
SIEETLGKIWADVLRVEQVGIHDNFFDLGGDSILSLQIIARANLAGLQLIPKQLFAHQTI
AELAAVVGTTKKIQAEQGLVTGALLLTPIQEWFFEQNLPEPHHFNQSILLLVPPDVQSEL
LEQVLQKLLLHHDALRLRFIPDGGDWQQVNDGLEAKVPLNVIDLSTIPAEEQSVALENSG
SALQASLNLSTGPLMRVALFKFSNNQPYRLLVILHHLIVDGVSWRILLEDLFSAYQQLSR
GEMMALPPKTSSFKDWGHRLREYARSLALTSELNYWMQPNFNFTSLPTDYPVSKDANNIA
ATAQVSRSLSLEETSALLQEVPAAYNTQINDVLLTALLQSFAQWTGSSSLLIDIEGHGRE
ELFDDLDLSRTVGWFTSLFPVRLQLEQTNHPGNILKSVKEQLRQLPNRGIGYGILRYLSP
YAEQLKALPQAEVSFNYLGQLGQKSSAADTWKLAQESGGVEHNSLENRNYLLDINVLTIN
GKLQINWTYSQKIHQLKTVECLADWFMNALKTLINHCQSPDVGGYTSSDFPEVSLSQEEI
DNLNLMFAFDPS
>B2JBV5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MSEYDRSGDIAIIGMSGRFPGAKNLEEFWQNLKNGVESISFLNDDRILGSGVSPSVLGHP
NYVKASSVLKDIDLFDAPFFGFSPREAEITDPQHRIFMECAWEALENAGYNPKKSNCSTG
VFAGKSISNYLLFNLLHTLDLTKATNYLQNLIGNDKDYLATHTSYKLNLKGLSVTIQTAC
STSLVSVIMGCDSLLSYQCDLALAGGITVRVPQEIGYIYEEGSILSPDGHCRSFDAKAGG
TIYGSGVGIVVLKRLADAITDRDCIHAIIKGTAINNDGALKVGYTAPSVDGQSEVIAMAH
AMAGIDAETISYIEAHGTGTNLGDPIEIAALTQVFRTTTQKKGFCAIGSVKTNIGHLDAA
AGVAGLIKTVLALKYKLLPPSLHFEEPNPQIDFANSPFYVNTKLSEWKTDGKPRCAGVSS
FGMGGTNAHVILEEAPALIPVANQVERSLHILSLSAKSQKALQELASRYENFLASHPEAS
HPDICFTAHTGRTHFDCRLAVVSESIAQMREQLGTFVAGVEAAGLVSGQVNEAESPKIAF
LFTGQGSQYIGMGRQLYEEAPIFRQTLDRCNDILRPYLEKSLLSILYPESEETSLIDETA
YTQPALFALEYSLYELWKSWGIKPDIVIGHSIGEYVAATVAEIFSLEDALKLISERGRLM
QALTQNGKMVAVFASESKVREAIQAVAVSSEVAIAAINSPQNTVISGGNKAVEAVCAVLE
AEGIKTKKLKVSHAFHSPMMEPILADFEKVAASIAYSAPKIELSSNVTGKLIGSEIATPE
YWCRHIKQPVRFAEGMKTLHDRGCEVFVEIGPNPTLLDMGHQCLDEVGVFIPSLRQRYSD
WQQLLQSLAALYVRGVQVDWFGFDQNYLRSRLELPTYPFQRQRYWIDKPGILIDTKSHLA
LNGIRNQVIHPLLGQRLQSAALKNNEIQFESKISENFPAFLEHHRIYQQTIFPASGYLEM
ALFAGAEVFKSDKLILEEFVIHQVLILPPNQEKTLQLILTPTGNLEYSFQIFSFNQVAEQ
SADLWILHASAKLLLSEKGLEIPHVNLEQLTQRSEEISPEDYYQKCCDQGIDYGASFQGI
ERLWRQNGEVLGQIRLPEALHLEAVNYKLHPSLLDACFQVLKAGIHDTNTEDTYVLVGLE
RLAVFGYPDSTLWSYAQMRPVKETNQQTLTADLQLVSPDGRVIITVEGLVLKQVSSEALV
GTAPQLLLNSLYEVEWRSQARLFPLSPAENLLTPSAISERILPQVNEAIGDQYKNWLILA
DSLGIGQQLATFLRARGQTCTLIFSGENYEQLAEQEFRIDLASFADFQQLLKETVGTGIR
GVVHLWSLEAPEAQDLTVTDLEAASHKACGSTLYLVQALVKAELKQPPTLWLVTRGAILV
GVESAVSGVAQSPLWGMGKVIALEYPEFNCVRVDLDPNAPDDNAQTLFEEIWSKSSEDQV
AFCKGNRLVPRLVSRQFQAPVVHNKLNCRGDSTYLITGGLGYLGLLVARWLVECGAKYLV
ILGRNSASFAANSQLRELEQMGTQVVVRMADVSQEGQIAQVLAEIKQSLPPLRGVIHAAG
VIDDSTLLQLSWERFSQVMASKVEGAWNLHTLTQDTPLEFFVLFSSLSSLLGNSGQANYA
AANAFLDALAHYRRNRGLAGLSINWGVWSLKESTPEPDRREGERLLGRKGMEFINSKEGL
QVLDYLLLQSSVQVGVLPVKWSKFLQQFPPGGEPPFFSEFVYQLQQQVKDGQSQVKQIEL
IRRLKEASANERLELLVAYLQDGVAKVLGISSSQQIDPNQSLNELGFDSLMSIDFKNKIK
NELGIELPIRKIAESSSVVQLALALIEQLALTSLIQSEQPSNELTDNLEEIIL
>B2J103|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MSVNDTFKNENMEGIAVIGMAGRFPGAKSINDFWRNLKDGVESISVLTDEDILNSAIDPA
ILNNPRHVKAGAVLEDIELFDAAFFGFNPREAAIMDPQHRFFLECSWQALEDAGYDSENF
AGEIGIYGGMGWNSYLLFNIASNRNLLSLEIGQQTLLGNEKDFLTTRTSYKLNLKGPSIN
VQTGCSTSLVSIYLACQSLLSYQCDMALAGGVSINVLQKAGYLHQEVGIMSPDGHCRTFD
AKARGTVGGSGVGVVVLKRLEDALSERDCIHAVIIGSAINNDGALKVGYTAPSLVRQAQA
IAQALAVADIEAETVNYVECHGSGTVLGDPVEIKALTKAFRTSTQKKNFCAIGSVKTNVG
HLDAAAGIAGFIKTVLALKHKLIPPSLHFEEPNPEIDFTNSPFYVNTKLSEWKTNSTPRR
AGVSSFGIGGTNAHIILEEAPIGEQGEQGRKYQLLVISAKTESALETATANLVNHLKQHP
NLNLADVAYTLKVGRRAMGYRRVVVCQDIDDAMNALQDPKRVLTSIQETSEYAAYTPSPA
DGLRDRDRPVALMFPGLGTHHINMALEIYQVEPTFQEAVDRCCLLLKPILGLDLRDVLYP
KNSSQKQNPSKPGLDLRKMLGRSEEPADEATQKLNQTFFTQPAIFVVEYALAQLWFEWGI
RPVAMIGYSIGEFVAATLAGVLSLEDALTLVAKRAQMIQELPAGAMLAVPLTEQEVQPFL
SEKLSLSAINGSSLCVISGCTEAVDELEHHLTQKGLACRRIVTSHAFHSKMMEAIAPGLH
SLVKTFNLQPPKIPYLSNVTGTWITAEQATDPSYWVKHLCQTVQFASAVQELSKKHNPVL
LEVGSGQTLSSLALSILQSDRLVDRVVLPSLRHSYERQSDIAFLLNTLGQLWLAGVQIDW
AGFYSHERRDRLPLPTYPFERQRYWIEPHKQTQVVAISQTCSPEHFQGGEAQEYQLPTNS
EIVSELSLHSRPHLRNSYVAPSSELEHKIASFYQQSLGIEQVGIYDNFFELGGNSLIGIQ
VIAQLRKNFQLELSLRALFEAPSVAELGLFIEEMIIAELEELTEDEAQELVSVFTQNQQA
LITVS
>B2J2F2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MTQTAQLSPSSVFVVSGGAKGITAECTIRLAQQQPCKFILLGRSELLETEPDYAQNSDES
ALKKCIMENLLSQGEKPTPMNVQKIYNKITSSREIKKTLAAIEKTGAKAEYISVDVTDTP
ALQEKLATAVQHFGAITGIIHGAGNLADKLIEKKTEDDFEKVYTAKVQGLENLLACVNPN
QLQHLVLFSSVTGFYGNPGQSDYAIANEILNKSAHIFKQSYPSCHVVAINWGAWDSGMVT
AELKKIFQERKIDIIPIAVGAQMLVKEMDNTNHETSQVVIGSPLVPLAAELDPELRTHRI
RRQMTLEANPFLHDHTIAGSPVLPATCAMTWSINASEQLYPGYRLFYYQDFKVLKGITFN
ETLAKEHILEIEEISKVNLERIELKAKISSKNLEGKTHFHFSAQLNLQREIPDAPIYESL
NLEPDNIITATGKDFYQNGGATLFHGPGFQEVKRVLNISPEKITTECLWPELTAKEQGQF
PVQWVNPYTTDLSMHALWIWTQHFHEEGCLPGKVEKFEQFEMIPHNETFYVSCEVKSKTP
SSAIANFIIHDRQGKIYSRMLGAHAIIWSMKMLRS
>A0A166D196|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudovibrio sp. WM33|TrEMBL
MTCTTGLQIVTPEDPIAIVAARHCEVEQVAKYPVQRLARCNQSVSDAASALHVRLLAPAP
CAPAEFRIPPIYERAVSALTLNLLWLVRQSKQDLNAGKFNCDPKRSDVIIGVCGGFDSTL
RNALKVSGVTELAGEYESQVLAGKRALHAHFGSTTHDKVGEMASIIAARMGLELGTNGRI
LALESAEATTYCAFETAILGLLEGASDMAWVGVGQRIEGAHMAQALASHLGGDKVFNEGA
SLYGLRRLKDAQRDGDEIIAVLDGMACTHSRSNSPQAFQELSERLSAPRQVAVCDHSAAA
IGLAKPESYGLAHSGADAINAALSTIHHQSPTTIFGQSLYEHVWALRLRAYNNEPVPARV
KAQQSDLIAIVGLGASYGPFDGLETVTEAFQVGRDGIAPLSTTALPRTTTFDVNRTVPLS
SYAELGSETQSAIVQQATSRTSSFPDKVHALAMQVGAEALSQVVSEDTEQLCHSVRWSII
VATQLCSTLERAVSNETHWPELSKVLSLAERDNQLDSVSLEAMLPGNIAHSLSEAHKLNA
KAMAIESACASSLAALETAVRQLRQNLCDAVLVVASELPNNPRDLTLCSAQRMLSADKIS
PFTDQADGFSPGDGAGAVVLRRLPDAQAEKQTILGLIRGIGGSSDAVSFTAPDPRGQIAA
MKRALQNAAMEPDHVGYIETHGTGTQRGDAIEIKALNEVYGGHRKIGLGSVKSLVGHSFA
AAGLAGLIRALGAVNTAHYPPTILRGSLSHGLDQQQGSWQISNIPLPWVNNGTLRCAAVN
SLGTGGTNFHMIVEAAPEPSTEFTENV
>A0A1B8YDV2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Photorhabdus namnaonensis|TrEMBL
MENSFTGLEIAVVGMAGQFPGADNVSEFWEMLRGGIDGISSFTENELKVNGISKEEYSRE
NYISAKGIINHPFKFAADYFGINHSDAVRMDPQIRLMIENCWQALNHANIDSKTYQGKVG
VFAGASSQWSWFKELNTQFSSAAEQFHVATLNDPSFCTRISYLLNLRGPSVTIQTACSTS
LVAIHMACQALQAGECDVALAGGVSVTHPHKSGYLYQEGMINSPDGKTRVFDENACGTVF
SNGVGVVALKRLEDAVQSGDRVFAIVKGSAVNNDGSDKISFTAPSELGQKSVIQDALEYS
EVDAEQISYIEAHGTGTLLGDPIELSALKSVFPGNGSCALGSVKSNVGHCDAAAGVLAFI
KVALCTYFRTLVPTLHFKKANPKLDLDNTPFYINTETKPWEVDDGDVRLAGLSAFGVGGT
NAHIILQEYENRAQPALADLQYQSLPNRLEFKPVANVQKERVQHAKVAEVHQARPYSFDK
ASLQTALLEMLKTHFAKDAITLKDNFFDAGASSLDIAQLHDKVNAEYGLSLKISDYYRYS
NCEKLAQHICSLGNSQTLPKSKRTPQNTSLISVSSEETRHHYPQHAVAVVGMSGRFPGSE
NIQEYWQNLLEGHEGIRFFSDEELLEAGVPAAVLQLDNYIKAKGVLSSSFDFDPEAFAYT
AREAQYMDPQFRLLHEATWQVLDDAGYGNQKYRPITGLFASCGSNHQWLERLKKEVTDST
EQFGVALLNDREFLTTRVAYKLNLTGPAVTVQSACSSSALAITLACQSLYSHQCDLALAG
GVSITTPVKSGYVYARGMVNSSDGHCRPFTKEASGTVFSDGLGMVALKRLEDALRDNDNI
YGVIAGFGVNNDGHDKTGYTAPNANGQANCIRQSLNMAGVKPDEIEFLEAHGTATLVGDE
IEIEGIKEALGAGDRNCVLGSVKSNIGHTNTAAGVASFIKAILALKHQILPMSCHVTETN
PDSLSNTRFTLIDQSRHWKCDNEIRTAGVSSFGIGGTNVHLTVKSIAQSVKRDNERSELV
VLSSKSQQGLAKIASKLHDHIQHADQEPNLTDLAYTLQLGRGEFDVRSSAVVDSIETLNA
MLSRLAAGKSEGREISDNAPGLVFMFPGQGAQYVEMAKGLYHELDIFKTRVDECHQLLRE
QFDIDLLSLLYSDGEDAEERSIELQNTRITQPVIFVISYALAKCLESFGIRASAMIGHSV
GEYVAATLAEVMTLEEALKLVASRGLIMQECEPGAMLSVASSREKVAPFLTDSVTLATIN
SPNSCVIAGPLEEVKAVQARLSQENYRCRLLKTSHAFHTAMMLPGVDKFRAELDKVDFKA
PKAAFLSNVTGQWIQPEEACSADYWIKHLCQAVEFQQGIETCLQEPALNVFLEVGPGRTL
STFVKQIADSHANISVFNLLRHPLEEESDRACLLKVLGALWSLGISIDWTALYQNVSPGR
ISLPGYQFIREPSLSEYHISSTTTGRTSETKITKKELTQWLYTEQWQPVELPAGNTGQAN
NIVCFVPSLAWCDAFTERFSQEGQKLKFVIPSPAYYVDGQVIGVTPGDKNSFDNLMTELV
NSSFLPDSIIFAWPLSGTKDITTSWFSVILLLQSWAKSGRLSEFRLLLATTALPEHSLLN
GLINVIAQEVTKCHPRIIELDTAESIEAACDILAQELTASDMRFIVKRSQQARFEKRYQQ
LENNEPITDVIAKKQLFKKQGVYLITGGLGDLGLLFAEHLVTRYGAKVILSGRRDLPQKA
QWGDVEVKAHPQSEIIDRIHQLSLINEGDIDYYAADVCDRQEMEALIGNIEAQYGQLNGV
ICAAGVTRGDSFQGINHITMENCQPQFDTKVYSYQLLAELLEHRQIDFCILCSSIAAILG
GLSFSAYSSVSSFADAFAKQQNQQGKPWVSINWDGWVFERKNADDAIGSSLEQLLIEPDE
GLYILERVLQSPLKAQLIVSTGDLNKRFEQWVGTHIRPFTNQSHSAHSRQTFSKQIFSKQ
QIVDTIMDIWQDFLKIHSINSGDNFFELGANSLDLVQVNKRITEALYIDLSVVDMFSYPT
SELLAGFIIEQNAMMVGEISVAAVENSKAAEFDTPLNSQRSQDHDADISKKIAIVGIAAT
FPEAENIYDFWQNLTYGKESISIFSKEELLEEGIDQALLNNPNYIRAKGVFPNAGEFDAT
FFGYTPYEARQMDPQVRAFHTCCWQALQDAGIKPKESRDKIGLYAAASGNLQWLAQAMAT
AEGSAGQYSAMTVADKDYMATIVSYKLNLTGPSMVLSTACSSSLVAVNEAIKSLRAGECD
VALAGGVSITLPTKAGYLSEEGMIHAKDGKCRPFDIQASGTVFGDGVGVVVLKPLQQALK
DNDNIYATIIGTAINNDGGRKVGYTAPSYQGQIDVIQTALKDANVSADTLSFVEAHGTGT
HLGDPIEFKALKHAFATDKKNFCKLGSVKSNIGHLNSAAGIAGLIKAAMALKYKELPPTI
NFARINPEIDIVNSPFIISNQYSRLDDSQGLLRAGVSSFGIGGTNAHVVLEQAPCVNRQT
LTKERSVVLPIVLSAPDEKSLDSYKKQLKRAIQSNVVDSHLNEMALSLMQRDVMPYLFVA
YSRDREGLLQRLSSPSSDYLYNSMTSERKVVYLFPGQGMQYAAMGLSLYHTNDLFKTWCD
RGFEIASEYCAIDLKQLFLSGEDDEKLYNTEFAQPLMFIIEYSLVQVLASYGVKPAAMLG
HSLGEYVAAAVAEIFSFADAIRMVCARGRLMQSTEAAAMLSVMCSATVAQTMLFGRLEIA
LDNSSELCVLSGSDEEITAFEQLCESRSIKTKRLKVSRAFHSRYMEPILADYERVIGDVK
LSEPKLPIISNVTGELSTKNLMVEPHYWVRQIREPVRFTQGLEELLASGDAIFVEVGPGN
GLSSLIKHHQDFNAKHVSLSLISRGKEEEPCIMESLGMLSLLNVNVDWQHELNETVAPSV
NLPPMPIRGKEYPKDVKRLQAIFSGQAGSDVTQLSTQSVARSQVSDVTQPKSMAEELKVI
WKDILGVSEVNGEDDFITLGGNSLSAVQVVAKAKSVKIPVDMNMLLSRKSLNEIIHLIDT
PRPSISSGWQYNTQFKPEFYGNDVSCMYSAVREKLKHDYGLNCPNSLMRASDGSLLFGFS
VQPSDSQGNILNDYQNYGALLDWPQLQESFSFSYHKQFFDDLASYTAYCIEELEKGKLVI
ITGSDYHLPFSPSYGLSDSEYLLRPLFDNLEIDEEEVIPHAFVLVGRTSGGYQVYDGSFN
YFGEISDHEFAQTVIGFKGLEFMKSHEVYHKSRPYLAISVVQTGAFLSTDHLLRGTLDKT
LSGLQTHTAITNGNTPIHHYVGISAVNKLMESPELLLAMTSGELEQFVKRWLSQLELLHR
FLAMVIPDHAQWWADNVAGMTETLRKLIAIDNQNLNANDVTGTMTLFKQLLESVIGKLVI
EKLVIEKLK
>A0A3N6E4J1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-17|TrEMBL
MLRTELIRPLPELLRAHADRFGGKVAFRDARRSVTYAELEQRTGRLAGHLAGLRLQPGDR
AAICLGNCVEMVESYLAITRASAIGSPFNPRATDAELAHLLDDSGARVIITDTAHLPQLA
RLLEDRRDLRVVVIGSRGVPADAPAGSLAFEALATTEPATGPRDDLGLDDLAWMLYTSGT
TGRPKGVLSTQRNCLWSVAACYAPVPGLSADDRVLWPLPLFHSLSHIACVLGVTAVGASA
RIVDGFEAEEVLDALREDSATFLAGVPTMYHHLVRAARRQGFTAPELRMCLVGGAITTAE
LRRSFEEAFGAPLLDAYGSTETCGSITINWPSGARVEGSCGLPVPGLGVRLVDPETGLDV
GSGTEGEVWVSGPSVMAGYHNQPEATAQAIQDGWYRTGDLARRDAAGYFTVTGRIKELII
RGGENIHPGEVEAVLRRVPGVADVAVVGKPHETLGEVPVACIVPGPEGLDPQALFAACRE
QLSYFKVPEELYEIAEVPRTASGKITRHVLLEQPARLRASGTSHYESLFRLDWVPLTSVP
PPAVPAGRWALVGQDTAHLTAGLLTRGLEVTAYPDPAALRTAVTAGAPAPDVTVLAAGRG
AGHDGARHHARELEDWLRDERFADGALLLTTRRAVAAAPDEDIADLWQSALWGHARCLQA
EHPGRLVLADLDGGDEQTAAALPLALSHDEPQFAVRSGVVLLPRFARAATLAAGEREPAL
DPRGTVLISEADGAAAAEAGRHLVIGHGVRHVLLVSRGGEADSAAADLKAQLTRAGARVS
LEACDLTDRAALADVLARSKRPLTAVFHTWGRQDPRTTGFLPAAAAAALNLHELTTDDHP
AAFVLFSSAAGLLGAAGQSEHGAAAAFLDALAQHRRAAGQPALSLAWGPGDGLGADGAPA
PRTGIGRLSAHDCRAMLDAARTADHAVLVALRTVPEALRADEIPALLRDIIEVTERSAPR
GSADGAALRQELTALPDAECDRVLLDLVRTHAAQVLGLPGGQAIGADRAFKEHGFTSVGA
VQLRGRLAEATGLRLAATAAFDHPTPAALARHLRDVLLDDTALPVPVPVVTAAADDDPVA
IVAMGCRLPGGVTSPEQLWQLVEQGLDAVTEFPADRGWDIDSLYDPDPDRQGTTYVREGG
FLHDAGDFDAAFFGISPREALAMDPQQRLLLETSWEVFERAGIDPTSLRGQHVGVFSGLM
HHDYGSSAAQAPQGTEGYLGTGTAGSVVSGRVAYTLGLEGPAITVDTACSSSLVALHLAA
QALRAGDCTMALAGGAAVMAEPGSFVEFSRQRALAPDSRCKAFAEAADGTSWSEGVGVLL
LERLSDARRNGHQVLALLRGSAINQDGASNGLTAPSGPAQQRVIRQALAQARLSPDQVDA
VEAHGTGTTLGDPIEAQALLATYGQGRPADRPLWLGSLKSNIGHAQAAAGVAGVVKMIMA
MRHGVLPQTLHVDEPSSYVDWTAGAVELLTEARFWPETGRPRRAAVSSFGVSGTNAHVIL
EHVPAPVPDGDGERTDGEGPLPLPVSARGHQALQAQAARLHAHLTARPEQELTDVAQALA
TTRAALEQRAVVVAADREEARHGLAALAEGTPAPSVLTGSADLEGKVVFVLPGQGSQWAG
MGAELLDSSPVFAQAMTECADALAPHVDWSLLDVVRQVPGAPTLDRCDVVQPASFAVMVS
LARMWRSHGIEPDAVLGHSQGEIAAACVAGALTLPDAARVVALRSRAIAQHLAGRGGMMP
VALAPDEAARRLAATAYGEQIAMAAVNSPSSVVLAGALDALDALAAELAEDGVRARRIPV
DYASHSAHVEQIEDELLRALRPIAPRSSDIPFYSTVDNRWLDTRELDGRYWYRNLRQTVR
FEEATRALLAQGFGFFLEISSHPVLTPAVQETVEHTGAEALACGTLRRDEGGLRRFFTSL
AATWVRGLPVRCSPSPHGTAARRVELPTYAFQRRRYWLEAAPEPGATATADPAEAAFWEA
VDSADPQALATTLSAEGQDPGADLSALAAALPVLSDWRRRHRERSAADAWRYRVTWRRLA
GDTAGTLTGRWLAVVPTTGAGAADAATGGQDTDTLLDGLRALGARFERIDVDPRHAEAGE
LAEVIRQHAQEKGDFDGVLSLLALDERAVPEAPGHTAGLAGTAALVQALADTDSGALLWA
LTRGAVTTGPGGPAISPSQAMVWGLGRVAALERPHTWGGLVDLPQTLDERALSRLAGALG
RRDGEDQLAVRPTGVFAQRLTPAPLGDAPPARRWEPHGTVLVTGGTGGIGAEAARRLAEA
GAEHLILTSRRGPHAPGAEELAAELRARGTRVTVAACEATDRDTLKDLLTNAPGEHPLTA
VVHAAGVGQDSPLDATDAQEFTRVLAGKAAGAALLDELLGDTPLDAFVLMSSGAGVWGAG
RQGAYAAANAYLDALAERRRAAGRTATAVAWGSWGGGIGLGAEAGTAERLRRLGLLGMNP
HSALAALVRAVEHDDTRVAVADMDWARFHAAFTVSRPSPLLQDLPDVRAAQAAPSTPDGD
EQRPATGLAARLAALSGPERDRAVLDLVRAEAAAVLGHTGADAVDATRAFRDQGFDSMTA
VELRNRLAEAAGLTLPSTLVFDHPTPTALADRLRGLLLGTGPEQPPVPGPAAAGPDDDPI
VIVGMSARLPGGVASPEDLWKLVDAGGDAVAAFPADRGWNVDDLYDPDPAKTGKSYVRHG
SFLYDAGDFDAAFFGISPREALAMDPQQRLLLETAWEVLERAGIDPQSLHGSRTGVFVGA
MHQDYGAGQSPDRRGVEGYFVTGNAASVLSGRVAYTLGLEGPAVTVDTACSSSLVSLHMA
CQALRSGECDLAMAGGVTVMATPDGFVEFSRQQGLSTDGRCRAFAASADGTGWSEGAGLL
LVERLSDARRNGHPVLAVVRGTAINQDGASNGLTAPNGTSQQRVIRQALADAGLTAADVD
AVEAHGTGTTLGDPIEAHALLATYGQDRPSDHPLWLGSLKSNIGHTQAAAGVAGVIKMVM
AMRHGVLPRTLHVDEPSPHIDWTTGAVELLTEPRDWSVDDRARRAGVSSFGISGTNAHVI
LEQAPAEDGPPSAGAPQHADDPTRSQQLPAVPWLLSGRTPQALRAQAERLVDFAEAPLAP
DAVDIAYSLTSRSALEHRAVVVADDRDGLLAGLRALARGEQAAALTQGASATGRCAVLFT
GQGAQRIGMGRELDATQPVFAEAFDEVCAELDPRLRHPLRDVVFGDDPTLLEQTAMAQAA
LFAVEVALYRLMESWGVRPDAVAGHSVGELAAAHVGGVLSLTDACALVAARGRLMQALPH
GGSMVAVDATEDDVLPLLAGFESQVSVAAVNGPSSVVLSGDETEVLRLAEELAARGHVTK
RLHVSHAFHSPLMEPMLDGFRAVVERLTFRPPTIAFVSTRTGTSVDAETLCSPDYWTDQI
RQPVRFHDAVRTLHDHGVRTFLELGPGGVLTAMVQDCLAEAGEAVAAVPTLRRDQSEPRA
VVSALARLHVRGVPVDWAPLFTGSAARRVDLPTYAFQRRRYWLDSGTAAGDAGAAGLADA
AHPLLRGLVTLPDSGGVLCTGRLSLSTHAWLADHTVGGAVLVPGTALVDAVVRAGDETGC
PHLDELIIAAPLVLPEQGAVQLQIAVAAPDRTGRRPVTVHSRPAEAAPDAPWTRHADGLL
APPPPPPTPRRPPPGPGRRRPHRAPTPTASTRPCARPVTRTDRSSADCTASGPTATRSTP
KSPCPTNGKPKQGSSACTPGFSTPPCTRRASAPCPASARTGCSSRSPGTASPCTLPEPPR
CASRSPRRDPTPSPWRPPTPRAHRSSRSPRWCSGPSPPTSCAATGPRTASSTTSTGPRCP
CPTAPRSPRARSSSTSPTPRRPRAPSGPANCAAASCGPSRTT
>F1TAA4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
MAGDFQSCPKGIETEVKKVVADLLDDKSEALDLDKSFLELGINSILSVELVEALEQRFEI
QLGIEVIFDYRGIKELAEFILDRYGADHMSKHCQNEPAACPSCTETGNPDLLNHKESAKV
EVENNNRNVSLPGEWGSNIAVIGISGKFAGSETIEEFWDHLEHGDSCIEQINRKGWDERN
YYDPYPDRKNKSISKWGGLLKNIDSFDASFFNISPLEAERMDPQQRLFLEEGYKSIEDAG
YSPEQLSGKKVGVFVGGRSSDYKEKTLMEEEINAQTFLGNDMSILAARLSYFLNLKGPSM
AVDTACSSSLIAIHSACGSIRRGESEIALAGGVFAISSPEFYIMTSKTNMLSPDGKCKTF
DNSANGIVLGEGVGVLVLKPLKAAIEDRDNIYGVIKGTAVNQDGKTKGITAPSMLSQKEL
IFNVYKNASIHPETVSYIEAHGTGTKLGDPIEIKALTEAFRMFTDKTKFCAIGSHKPNFG
HTIMSAGIAGVLKILMAMKYRKIPPTINITQINEHIDLNGSPFFVNTRLMEWENRGGIPL
RAGVSSFGFSGTNCHVIIEEAPIQKRCQDGINRPYYLFLISAKTKKALSRKISDMAKWID
KEAENYLIEDITYTLLTGRSHFPVRCAFIAKDLSELKQRIREINEKGTAEEYFQNEENDS
LKMEKVLEPILREYGERLIKELQEPDNLTWNEYKEKLLVLSNLYIKGCNLNWEDLFINCK
THRIALPAYPFAGESYWITETGNRYIKEDHSVSIHPLLHKNTSNFSEQRFSTFFTGREFF
LADHVVKGERILPGVVYLEMARAATAAAVDASEEDKTGLQLKNVVWIRPVVVRDKPVLIH
ISLLIEENGEISYKIYSGNDGDSDEIIEYCQGSVAPNEAVEPQLLDIEALKAECNLGSFS
ASECYDAFKAMGADYGMRLKGIEKVYVGEDKLLTKISLPEAIYDTQDMFDLHPSLMDSAV
QICLMMGSGDMKSFDSKSPRNPLLPFALQSLEIIDKLAQKMWAYVRYSDGSGAKHEVQKF
DIDLCDEKGFISVRMKGFCERVLEGEVRTKKANETSIKHFPGTMMLTPAWDIVPIKRGKT
FPSFTDRVVVIEGTKDKQSAIQQYYPQAQVLDIHPNDTIEEIYKKFKDYGSFEHIIWIAP
HRSLDSLADDLLVEEQKKGVIPVFRIIKALLRLGYGEQNLGWTVITTQTQSIGKNDIVNP
THASLHGLVGSMAKEYPNWQVRLVDVEDDCQWPINDIFTLSADSQGELLVYRDKVWYRQK
LVSAQVTELNQPLYRQDGIYVVIGGAGGIAEVWTEYMIRNYQAQVIWLGRREEDESIRMK
INKLAALGPKPYYISADATDEKALAQAYKEIKMRHPRIHGVIDSAIVLLDGSLANIDEAR
FKATLSAKVDLSVRIAQVFQKEELDFVMFFSSVNSFLKSAGQSNYVSGCTFKDAFARQLS
LEWDCAVKVMNWGYWGNVGIVASDHYKDKMVQLGIGSIEPQEAMEALETLMAGQLDQLVF
LKTTKNSVFEELNLHVDTEEWIAAYPENIPSNIYSLQERIKTVPLPKLFDGRM
>A0A1T7ZYN7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus subsp. massiliense|TrEMBL
MLRREASALLAYVAEHPRIAPNRIAGMIFRTRVARRYRALVTVENHDQLVAALRTVVAGT
EHPLVVRNSEPATARRHGFVFPGQGGQRPGMGRLFYDAFPSFRAEVERCADLFAKQFGRS
PLSYLLDDQLPPNDSATVVQPALFTQMAGLAALWRTVGVIPRAVVGHSQGEIAGAYVSGV
MSLDDAVTVVGTRAGIADKFPADDYAMAVIATDRDTCEELLARNSGWAELSVINSPSMVG
ISGQRETVHQIVEHLTGDGVFARVIPVRYPAHTSMIASIGAQIRHALTENLHAGEFTVSE
IDCIGATLGTAISPEMPVDEYWFWNLRNAVRFDRAVATAAAAHIDTFVELAEHPTLQLAL
RENLAALGSERTACVVSTSHRNATDLAEFTANLAKIAVHDLDYNWDALRAEAPDRVSLPL
RDFPNVQNNDIPLWLSYRAGTSGVAVPKQPAVTPEAERRVDTGNDSRAYPRLLREAWTKM
TRRSMMPPRSYAFIDGTGDAGALVEALRDNAPNFGSSARIVTGTNESGAGDADTVVIVLP
SPALLDDREAAEAVARFFGNRTWWPGLSSTVTGCWLVTVGGEQAVADDRPAHPVHAAIAA
GFRCMGTEHPGIAFRHLDLTPDIAGPDKADNILAALQSAGESELALRADGMYAKRVLDID
QDGDESSRAVAPDHVVITGGTGKLGQEFCEHYARMGTRQITLISRSGETDAVTGRLDAIR
RSTGAKVRALPCDVTDTAAVTALADQLRDTPADLIIHAAVDYSDTPLAEVTVDKFQDALR
AKVIGISNVLDTVPRTDSCRVMLCSSLAATIGGKGQLMYAAGNRMLDVLASTRRASGLDC
TSIQWGQWTVHLDLGDTGIAKLAAAGVHPMRPADALAVGMGRHHGNTLVGAFDLTQARAM
LGVFGYGPLLSELEDNGGPVAPAETIRPAPVVPENRSGHLVQLLAEVIGADHADSIDTAM
PMVAMGLDSLQALEFRRRVQAELDFELPVQDLLGGASVDHVIDALTAQSR
>A0A3N6ER15|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI96-15|TrEMBL
MAARFDPRALAAGGADGAVGPMARDDRARTSVPLRRRTVASVAQPDGPALPARLAGLGDA
ERHQLILRTVREHAATVLGYDSATAIPVERGFQDLGIDSLTAVELRNRLKTETGLPLAAT
VVFDHPDATRLAHHLAQALAPADADGTPADGDGDGDGDGDGSGDADPGRRAHTGRAASTA
PEADAPDVSGRLESADADELFDFIDREFGPN
>A0A5P9PH50|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Amycolatopsis sp. YIM 10|TrEMBL
MSNDEKLRDYLKRATAELHETRRRLRETESRQHEPIAIVAMSCRYPGGVTTPEQLWELVA
DGRDAISSFPKNRGWDAEGLYHPEPATPGKTYSVEGGFLHDAGAFDADFFKISPKEARET
DPQQRLLLEAAWEAIERAGIDPTSLRGTRTGVFAGVAYHDYAGRSGLGERGIGTLGSVVS
GRVAYSLGLQGPAVTVDTACSSSLVALHWAVRALRAGECTLALAGGVTVMSTPDAFVGFS
QDRGLAPDGRCKSFAAAANGTGWGEGVGLLLVERLADAVRHGHPVLAVVRGTAVNSDGES
NGLSAPNGPAQQAVIEAALRDAELTADQVDVVEAHGTGTRLGDPIEAQALLATYGQGRAE
DRPLWLGSIKSNIGHAQAAAGVSGIIKMVGALRHQVLPKTLHVDEPSGNVDWTAGTARLL
TEPRPWPENGGARRAGISSFGLSGTNAHVIIEAAPPVEKPPTPEPAAKASVVPVVLSGKT
AEAVRAQAQQLLSEVDGEMGLPDLGFSLATTRTAFEHRAVVVADDRDRLVRGLTALAADE
TTTGLVRGTANADGQTAFLFSGQGAQRLGMGRELYETYPAFAAAFDAVCAELDPKLREVI
WGDDSDLVNQTEWVQPGLFAVEVALFRLVESWGIRPDFVAGHSIGEVAAAHVAGVLSLPD
AAKLITARGRLMQALPTGGAMVAVQASEQEVLPLLSDQVAIAAINGPEAVVLSGEEAAVL
AVANQLSGKSTRLKVSHAFHSPLMEPMLAEFAVVVEQLSLREAVLPFVSSALEPDVTSPD
YWVRHVREPVRFADAVRLLEERGVTTFVEVGPDAVLSSLGGFTPLQRRNKSEELELVTAV
ANIHTRGVVVDWHAYYDGRGARRIDLPTYPFQRRWYWWELGATSVSAPDSEFWAAVDREE
FTGLADELKVDAAALGEVLPAMSAWRTRFTDESTVDSWRYRVSWRPVGADGGGALAGTWL
VATPAAPTAPDDRIQAIIDGLEARGATVRSIEVADADRAELANRLRSEQPSVVLSLLALD
DRAHPGHAPLTRGGADTVTLVQALGDAGLTAPLWCCTSSAVAVDPAEEVTGAAQAMVWGL
GIGLALEQPDTWGGLVDLPTTLDEPALDHLVTAVSGVGEDQLAVRAGGLFARRMVRAPLG
ATPAARTWRPSGSVLVTGGTGGLGARVARWLAENGAEHLLLVSRRGVAADGAAELAAELA
ALGAKVSIEACDVADRAELRKVLDTVPEDQPLTAVVHTAGISQRAAPLGDLTLAEVAAIG
EAKVTGAANLDDLLGDRQLDAFVLFSSGAAIWGGAGQAAYAGANAYLDALAHRRRAAGRT
ATSIAWGSWEGGMVDAEVSAQSRRIGAPPMAPRLAITALGRALDHDESHLVVADLDWPRF
VPTYTLARPRPLLDELAEVREVLDGSQAANSVTTTGLIEELAGKTEAEQHRTLLDLVRTQ
VAELLGYDDANAVEPGKPFQDLGFDSVAAVDLRTRLGNATGKTLPATVVFDYANPKALAE
YLRAELCQDGGRDPLAELDRLEALLTGLPPEDIEQHRLTGRLQALIGRLDERAGVAKAED
QLDTASADDIFALIDNELGLG
>A0A2K8PBR0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces lavendulae subsp. lavendulae|TrEMBL
MTTPDVKVVEALRASLKETERLRRRNQELTDASREPIAIVGMSCRFPGGIGSPEDLWKLV
ESGGDAISGFPADRGWDVESLYDPDPDHAGTTYARHGGFLHEAPDFDASFFGISPREALA
MDPQQRLLLETTWEVFERAGIDPGTLRGSRAGVFVGASANAYGAGSGELPEGVEGHLLTG
TASSVVSGRLAYVFGLEGPAATVDTACSSSSVALHMAVQALRQGECSLALAAGVTVLAGP
EVFVEFSRQRGLSPDGRCKSFAEAADGTGWSEGVGVLLVERLSDARRNGHRVLAVVRGSA
VNQDGASNGLTAPNGPAQQRVIRQALESARLAPADIDVVEAHGTGTTLGDPIEAQALLAT
YGQDRPEGQPLWLGSLKSNLGHTQNVAGIAGVIKMVMAMRHGVLPRTLHVDEPTSHVDWE
AGAVSLLTEQRAWPETGRPYRAGVSAFGVSGTNVHTIIEQAPEADRTTETVPESGSGAPT
GVPVVPWILSAKGRDALREQAARLLAHAEEHPGLDPVDVARSLAVGRSAFEDRAAVVAAD
REGLLAGLAALAEDGSAAGVVTGSPQGGKVAFLFTGQGSQRLGMGRELYDAFPVFATALD
EVCARFELPLKDVLFGTDAGLLDETRYTQPALFAVEVALFRLVEAWGLKPDYLSGHSIGE
IAAAHAAGVLSLDDACALVAARGRLMQALPSGGVMIAVQASEDEVLPLLTDRVSIAAVNG
PTSVVIAGDEDAAVAVVEALSDRKTKRLTVSHAFHSPHMDGMLDDFRQVVQGITFGAPRI
PVVSNLTGALVSDEMGSAEFWVRHVREAVRFLDGIRALEAAGVTTYLELGPDGVLSALAQ
DCVTDGNPAFAPLLRKGRAEAETLVTALAQAHAHGATVDWAAYCGGTGTRRVDLPTYAFQ
RQRYWIEPGAPSGDLGAVGLDEAAHPLLGATVALADSEGFVYTALLSPTTHPWLVDHAVM
GSVLLPGTAFVDLAIWAGDQVGCDLVEELTLEAPLVLPERGGVQLQMHISAPDGDGSGRR
SFSISSRPKDGATDESWTRHAGGVLAPGAAPAPAPFAAGQWPPAGAEPLATDDLYADLAE
VGMGYGPAFRGLTAAWRHGDGICAEVALPEEVASAAADFGLHPALLDAALHTLGLGVLGG
TEGEGRLPFAWSGVTLHASGADALRVHLAPTGTGGGVRLEIADATGAPVATVDSLVLRAV
SAEQVRAAGTAHHESVFRVEWTALPAPAAPAGRWAVLGAAVPAALLGAVPAGDAITVHAD
LADLAAAVEAGAPVPEAVFAAYGQAADGADTDAAPELSADAVHRAAHHALALAQTWLGEG
PFTGDRFAVTRLVVLTRGALTTGADGTATDPSGDAVTEPVTDPVHAAVRGLLRSAQAEHP
DRLLLLDTDADEASVRALPAALATALASGEPQLAVRAGTVLVPRLARVARDAEAEQPAPA
GFAYTPGSTVLITGAGGLLGGLIARRLVAEHGVRHLLLVGRRGGSTPEAQALGAELAADG
VTVTWAACDVADRDALAAVLAAVPAEHPLGAVVHTAGVLDDGVITSLTPERLSAVLRPKV
DAACHLHALTRDLDLSAFLLFSSIGGVFGGAGQGNYAAANVFLDVLAQHRRSLGLPATSL
AWALWADGAGMAGSLSDADVSRMTRGGLPPLTSAEGLDLFDLVHRLDEPAPVLMRVDLPG
LRAQAQNGTLSPLLRGLVRVPVRRSANGAATAGGLSGLRQRLAGLPAAEQDRMLLDLVRK
QVAAALGYPGASSVEPGRSFKELGFDSLTAVELRNLLGEATGRRLPATLVFDYPTATALA
QYLREEIVGDLAADAALPARRAAATTARAEDDDPIAIVAMSCRFPGGVRTPEDLWRMLAE
GRDGITAFPADRGWDLDALYSDDPDREGTSYVREGGFLHEAAEFDAPFFGISPREALAMD
PQQRLLLETTWETFERAGIDPTGLGGSRTGVFVGSNAQDYLQLWLNDGDGLEGHLGTGNA
ASVVSGRISYSFGLEGPAVTVDTACSSSLVTLHLAAQSLRRGECDMALSGAVTIMSTPGA
FTEFSRQRGLAENGRIKAFAASADGTIWSEGVGLLLLERLSDARRNGHPVLAVVRGTAVN
QDGASNGLTAPNGPSQQRVIREALADAGLTAADVDAVEAHGTGTKLGDPIEAQALLATYG
QDRPEGRPLLLGSVKSNIGHTQAVAGVAGVIKMVMAMGHGELPQTLHIDEPTPYVDWSAG
DIELLTERREWPETGRPRRAGISSFGYSGTNAHAVIEQAPQPAAATAPAPAPAGPGLPVL
PWLVSGRSAAALRAQAERLIPTAADAVAAPGGRGALDLGYSLAAHRAALEHRAVVLGAPS
DGDALVARLTALAVGEPVPGLVRGTVSSGGLAFLFTGQGSQRLGMGRELYDAFPAFAEAL
DAVCQGLSLELPLKDVLFGADAALLDRTEYTQPALFAVEVALFRLLESWGVRPDFLSGHS
IGEIAAAHVAGVLSLEDACVLVAARGRLMQALPSGGVMIAVQASEDEVLPLLTDRVSIAA
VNGPTSVVIAGDEDAAVAVVEALSDRKTKRLTVSHAFHSPHMDGMLDDFRQVVAGLAFET
PRIQIVSNLTGAIVSDEMASADFWVRHVREAVRFLDGVRALEAAGVTTFLELGPDGVLSA
LAQDCLTGDADVALAPVLRTGRGEAESLGGAVAQAHVRGVEVDWSAYFAGTGARRIELPT
YAFQRRRYWPETVLSVGATAPVTAVGAVDARFWEAVESGDLSSLASELHVADDARVSDLV
PALSAWRRQGQEQSEVDGWRYRVSWKPVADSVGGARLSGVWLVVVPAGGVDDSAVVEGLT
ARGAEVLRVVVEPGTDRAALAGLLTGAGPVAGVVSLLALDEAAGVVATAALVQALGDAGV
GAPLWCLTRGAVSVGRSDRLVSVVQAQVWGLGRVAALEVPERWGGLVDLPEVWDERAMGR
LAGVLAGGLAGEDQVAVRSSGVFGRRLVRAAAGDSGSWVPSGTVLVTGGTGALGGRVARW
LAGAGAERLVLTSRRGVDAPGAAELAAELAETGVEVSVVACDASDREALRELLAAEAETL
TAVVHTAGVLDDGVLDALTPERFESVLRAKATSALNLHELTVELGIELSAFVLFSSMSGT
IGAAGQGNYAAANAYLDALAEQRRAAGLAATSLAWGPWAGSGMAADEAMDARMRRGGIPP
MNADLAITALRQAVGSDEAALTVADFDWAAFAPGFTAVRAGRLLADLPEAATRSAERAED
RPERTGSSLAEQLRGLSAGDRAPFLLDLVRTRVAEVLGHSGADDVEAGRAFREIGFDSLT
AVELRNRLGATTGLRLPATLVYDYPTPAALAGYLLAELLGAQTEAAGPVATVVDDDPIAI
VAMSCRFPGGVRTPEDLWQLLASGTDAIAELPLDRGWDLDALYDADPGAQGTSYAREGGF
LYDVADFDADFFGISPREALAMDPQQRLLLETSWEAFERAGIDPETLRGSQAGVFVGTNG
QDYLSVLLEEPAGLEGHLGTGNAASVVSGRLSYVFGLEGPAVTVDTACSSSLVALHWAIQ
ALRNGECSLALAGGVTVMSTPGTFIEFSRQRGLAADGRIKAFAAGADGTGWGEGVGMLLV
ERLSDARRNGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLSAAEVDAV
EAHGTGTTLGDPIEAQALLATYGQDRPEGRPLLLGSVKSNIGHTQAAAGVAGVIKMVMAM
QHGQLPESLHIDRPSPQVDWEAGDIELLTERREWPETGRPRRAGISSFGFSGTNAHTIIE
QAPDAESGADTAASVDPGLAPLPLVLSAKGAAGLRAQADGLRARLLADPGLRLSDVARTL
AVGRSAFEDRAAVVAADREGLLAGLAALAEDGLAAGVVTGSPQGGKVAFLFTGQGSQRLG
MGRELYEAFPVFAEALDEVCAWFDLDVPLKEVLFGSDAELLDRTGYTQPALFAVEVALFR
LVESWGVKPDFLSGHSIGEIAAAHVAGVLSLDDACTLVAARGRLMQALPSGGVMIAVQAS
EDEVLPLLTDRVSIAAVNGPRSVVIAGDEDAATAVLEAFSDRKSKRLTVSHAFHSPHMDG
MLADFRRVAEGLAYESPRIPVVSNLTGALVSDEMGSADFWVRHVREAVRFLDGIRALEAA
GVTTYLELGPDGVLSALGQECLSVDGAAFVPLLRKGRPEAETAMTALARSHVRGIGVDWR
AVHGTGAVRVDLPTYAFQRQRYWPRTPLVRRGGSQPRTGTDGWRYQVSWKPLTDSAAGAA
LSGAWLVAVPATGVDATAVVDALAARGAEVRRLVVEPGTDRAALAGLLTGAGPVAGVVSL
LALDEAAGVVATAALVQALGDAGVGAPLWCLSRGAVSVGRSDRLVSAVQAQVWGLGRVAA
LEVPERWGGLVDLPEVWDERAMARLVGVLAGGSGEDQVAVRSSGVFGRRLVRAAALAEDA
PSWAPSGTVLVTGGTGALGAHVARWLAGAGAQRLVLTSRRGADAPGAAELAAELAETGVE
VSVVACDVADREALRTLLAAEADTLTAVVHTAGVLDDGVLDFLTPERFESVLRAKADSAL
NLHELTAELGIELSAFVLFSSVTGTWGTAGQANYAAANAYLDALAEQRRAAGLAATSIAW
GPWAEGGMAADGALESRMRKGGVPPMAAGPAIGALHRALDADDAVVTVVDVDWDRFAPGF
TAGRAGHLLAELPEARGALAARAGTDGRSDTAADGRDSLAGRLAGLSAAERDRMLLDLVR
KEVAAVLGHTGVERVGAGRAFKELGFDSLTAVELRNRLGTATGLRLPATLIYDYPTSADL
ADHLRGELLGTGDAAALAAVSDRTGRAVEDDPIAIVAMSCRFPGGVRTPEDLWRLLASGG
DAIGEFPADRGWDAEELFGPRSEQEAAYAREGGFLYDVAQFDPGFFGISPREALAMDPQQ
RLLLETSWEAFERAGIDPSSLRGSRAGVFVGTNGQDYLSLVLNSADGGDGFMSTGNSASV
VSGRLSYVFGLEGPAVTVDTACSASLVALHLAVQALRSGECSIALAGGVTVMSTPGAFVE
FARQGGLAADGRIKAFAEGADGTGWGEGVGMLLVERLSDARRNGHPVLAVVRGSAINQDG
ASNGLTAPNGPSQQRVIRQALASAGLSAAEVDVVEAHGTGTKLGDPIEAQALLATYGQDR
PEGRPLLLGSIKSNIGHTQAAAGVAGVIKMVLAMRHGVLPQTLHVDAPTPHVDWTAGDVE
ILTERRDWPETGRPRRAGVSSFGVSGTNAHTILEQAPEDPEAEGAAESAGGSTWPWILSG
KTQAALRDQAARLLAHLGDQRPVDVGHSLATGRALLDHRAVIVAGAEEEYREALTALAAG
DSAAALTQGVATTEQQVAFLFTGQGSQRPGMGRELYDAFPVFADALDAVCARLDLELPLK
DVLFGSDAEVLDRTEYAQPALFAVEVALFRLLESWGVRPDFVSGHSVGEIAAAHVAGVFS
LEDACTLVAARGRLMQALPAGGVMIAVQASEAEVLPLLTDRVSIAAVNGPTSVVVAGDED
AAVKVAEAFPDRKTKRLTVSHAFHSPHMDGMLDGFRKVAEGITFAAPRIPVVSNLTGALV
SDEMGSAGFWVRHVREAVRFLDGMRALEAAGVTTYLELGPDGVLSALAQDCVTEDAALFA
PLLRKGRGEAEALAGALAQVHTRGVTVDWTAFYAGSGARRVDLPTYAFQRERYWVDSFAP
SQDAVSLGIESAGHPLLGAAVELPDTGGFLFTGRLSRRTHSWLAEHVVADSAVVPGAAFV
ELALRAGEEAGCGHLEDLLHEAPLLLPEDGAVQLRVTVGGADATGRRTVQVHSRTEAGDG
DVANGGTWSRHATGHLTETGAETEGSGSTAAATGPWPPTDAEEVPVAELYDRLAAAGQYH
GTALRTLDRAWVRGDEVFAQARLSDELRSSAAGFALHPALLDAAVQMLGATTGTAGTLAR
EALTWRGVRLHAAGADTLRLRVTPGATDTVSAELADEQGAPVASVEALVTRELDAERFAV
ADRHAAHDALFRLDWVRTAVPAGAGAATLVVVGDADARSGLAATLGGAGVPVAAYEDLAA
LDEAVTAGRQALPDTVVMPFTAPEGTAPAGVAALDTVADGAREVTHRALAALQDWLGNGR
FAGARLAVVTHGAVAAHADTEAGDLAGTPVWGLVRAAQTEHPDRFVLVDLDGADASGRAL
AGALASDEPELAVRGGALYAPRLARVAAADRTGAATGADGAAGRIDASGTVLVTGAAGGL
AGLLTRHLVTEHGVRHLLLTGRRGGESEGAAELTDELAALGAEVTWAACDVADREALTAL
LASVPQERPLTAVVHTAAVLDDGVVDLLTPERVDRVMRPKVEGALHLHELTRHLDLSAFV
LFSAAAGTLGGAGQANYGAANVFLDALARHRRARGLTALSLVWGMWAEERGMAGRLTEAE
RARAARGGVAPLSAAEGLALFDAALAAAVTEPVLLPVAVDLPTLRARAADGGILPVFRGL
VRTPVRRRRPTAVPAGASAAGSGASHGGAEQTPAQRLAGLSPAERERTVLDLVRGQVAAV
LGYKSAEHIGEEQAFKELGFDSLTAVELRNRLGAAAGLRLPATLIYDYPNPAALARHLLD
ELAPEGTSGRRLSVLEDLDRLEGTFSSLDPAELAVAAGDDAAHARVAVRLQTLLAQWNDA
RTAADGTAAGEIEDASDDELFALIDKKFGQG
>A0A447Z1L6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Staphylococcus delphini|TrEMBL
MNNVIKCYDSDKHLWVFTGQGSLNLKNIKHLYNKNNTFKFYFSKYISQLEDILNISIMKM
ILDESSELNQRTDLEQPITVALQLAIARMWNGVNFYPSVVIGHSIGEYSAAVIAGVMEPS
DALLLATHRGNLMSKSPEGGMAAVFKGIKELLPLPNDIVVAAKNAPDLTVISGPYQQLEK
FLNINHRDNYVMLNVGHAFHSPSMREAASKFENYVQKTKLKYPNKSVKFISTLTGNEETE
KLTSTNYWVEQIVQPVNYLKAIKTCKQMFPNVSSVSELGVSSTLLNITKKTLINTGKIKY
IPFDSNIKIVKRKNKLYNSKPIPWNKPKINNRFQESMLNKYAFETNWELISLSKADFDMN
ETSYLVISENSIDNLPPKWKQIDGKDLDIVKEMIQTKVWDGIIVFSTDIEDDVYKSLEIL
KYLASDTNIIQTPISFVNHFDNINNSGIQGLLKTFRLEYPEAQVQYIKYKDENNIFSNIL
YCMYQSSEEDLLIESDKEIYGSRLNRSSKLDELKELELNPNGTYIISGGQGALGLVSLRL
LVKKGARNIILLSRSSLRDDVHEELNVLRKESSIELLKCDVSNKEDVRKVKEWLSEMSWP
SVKGIIHAAGVLSDAVIQNQTSESFEVSYSAKVHGAHNLHDMFLPPDFLLLFSSAAAIFG
SAGQGNYAAANSTLDTLAEKWNYNNENVLSIQWGAWSDGGMAERHSAADYSEKIGFGSIS
NELGSQMIEQVLANKLKGVLCFTPINWSEFTSNTSFISNFISKKRELNNDISKIDVYSTV
KSIVYDTLGKSLDDYDSLLDNGIDSLASVSIRNKIMNIFDVNLTPSLLFDYPNIKAITKY
INSELVGYNTKNLGYENYIQSSLPVLVIGAGVSGISFARKLESQGISTIIMESKSEIGGV
WSNLANSHSKLQIDSPGYGFDCTVPPSLNTHKWSSVFPTRDEILKELKSISTSLEGEILY
NTHVEKVKKISENEYEITYIQNSSEKSINVSGVAAFTGGLHKPIKKKIPNEDCFKGHIAS
GISNDTPRDIFKNASVAILGHGAFAIENMRTAFENGANSVTIICRKRNLVMPNFGNWLLN
SSDSTMSAKDVIEVMRPFYKACGINIEELNAIIEEQNGEWKINQNTVPAGSDLYFLSQIL
GKLKVVIAEPEKLTEDSLILNNGQSIECDVFLKCLGSKTDDSIIKNIFGDKATIHGLWIN
EDPNLITYNDGTNGSQTLNNVKSLLCSSYTFFVQSFVQPYIDYRKDPIKFDKLMKRIKNN
PKESTVEILYTELWDYLEKAKKNLAAHVEEECPFDVFQSKCESEWEYYSKLLANDTSSTI
SLWELMKPTLHIIKKRNPSLPIETRKYSPLFGFISTYIPSKPRVLFLAGQGTNSQLSKEL
LNQTGWLKHSNLDFVIPDAPFEMPAFTNEEQLELLGLDELSKSGKYKKILPTGSGNQGLN
YCTIIMKIMTLFIYLLQIIYNGKLL
>A0A2K8PAP5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces lavendulae subsp. lavendulae|TrEMBL
MVSLAEVWRAAGVRPGAVIGHSQGEIAAACVAGILSLEDAARVVALRSQAIGRVLAGLGG
MVSVPLAAAEVRERIAAWGEERISVAAVNGPSSVVVSGEVQALEEFLAACERDGVRAKRI
AVDYASHSAQVELLREELDTLLAPIAPRAAGVPFLSTVTGEWVEGPELDAGYWFRNLRRT
VELERTTRTLLDQGFGVFIESSPHPVLTVGLQETVEDTGREAAVLGSLRRGEGGLERFWL
SLGEAYVRGVTVDWDAVFAGTGAQRVDLPTYAFQSQRFWPEAAPVDAEAPPAENALDARF
WDAVEREDVTALAEALAFETPDAIQSLGTVLPGLSSWRRQSREESTVDGWRYRVTWKALA
EAAPTRLSGTWLVAVPETLTGPAGDTAAAVLRTLAERGAAVRTLTIAAGVAHRDALTAAI
EAATGEDTAPEGVLSLLALGGEGAFAAGLALSQALGDAHVTAPLWCLTRGAVAAGRVDRV
EDPEQALIWGLGRVASMEHGERWGGLVDLPAEVDARVLERLVGVLAGDGAEDQVAVRSSG
LFVRRLVRARLSETAAVREWRPAGTTLVTGGTGALGAHVARWLAANGAEHLVLTSRRGEA
APGAAELREELTALGAGVTLAACDVSDREALAALIAAVPADRPLTAVVHTAAVLDDGVIE
TLTPEQVADVLRVKVDGTRNLHELTRGLDLSAFVLFSSFAATFGAPGQGNQAPGNAFLDA
FAEYRRAEGLPATSLAWGPWGSADGDDSAAGDRMRRHGILAMSPDRTLTSLRHALDRDET
TLTVVDMDWKRFTLAFTADRARPLLLELPEARRVIESAERESAEDLTGGVPLTRQLAGLP
EVEQERLLLDLVRTAVAAVLGHPDTTAVEAGRAFKELGFDSLTSVELRNRLGAVSGLKLP
ASLVFDQPTPAAVAAYLRAGIVPDAVAGGAPLLEELDRLESVLEQGTGDNVVRARVTMRL
QSLLARWNESGDPAAGPAGPGAADGSAAGGPAGEAADGADSGIDAVEQLQDASDEELFAF
INKGLGRY
>D6Z779|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Segniliparus rotundus (strain ATCC BAA-972 / CDC 1076 / CIP 108378 / DSM 44985 / JCM 13578)|TrEMBL
MEFAIVGASIRLPGVCDIDEFRRALLAGQSGLCAVPPSSDDGKGPTVHDPRYVPVASVVE
SAELFDREFFSMTSGEAASLDPQQRLLLTLAYEALQSCAFDPEMRRIGVYVSATQSSRRP
DAPARQQASGPLAVDYSAMLANDTDFCSARIAHKLGLTGPAVTVQSACSSALVAVHQACA
GLAFGDADAAIAGGVSVTLPQNRGYLHQEGGVLSPTGQCRPFDRGADGFVKGNGGALVVL
RRLDDALADGDPVLAVISGSAVNNDGDRRMGFTAPSPQGQEELIASAVARSGVAVGDIRY
VEAHGTGTPMGDPIEFRALTRAYGAGPGASPDCCLGSLKANYGHLDVAAGAVGLVKAVLV
VHGGTVFPQINFTGPSEFVPLAAGRFVIPTEPRQFPEHSWAAVSAFGMGGTNAHVVLRGP
RDGEISPVRAGQADGCAVPVRFNARSERSLARFGSRLSRYLRERPDIHPADVAATLARRS
VGGLVREVRARDSAELADELAAQDFGVARETIAAVPGRRVWLPPTPLEEAPLSSSGAVSE
PGGAERTPAPRAAQVRASFMRHVEDELGPPVGEEDDFFAAGGESIGLVAIVAKVTAEFGF
VVDFTRLDGLSTVGKLADELVRQAVSTVHDTDPIITFGPPGDVYWHPPAGGANFCYSALS
RVCPKLGVNAFRANLRDTASTIEDIAARNIEVLDRRGLLGGQLVLGGYSFGGNVGLEMAI
QLERAGVQPRRVVLFDSIAPHGYRGADTTGEEYDKAVALMVQSAVRQSAPEDQLGAFSRM
LGDQGSAAGVLYQDFVRFWRANHQALVRHKPEAVLSCPITLFRSQEALPQQSLQWLGVDA
LPASAWQRYSAQPLQVINVPGDHYALFVEPQCLEVLAARLPEVLGRNA
>A0A4R8SUJ1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides salmoniphilum|TrEMBL
MSQISPTAAMESDPIVISGMSIEAPGGIETPGAFWAALADGRELIGPFPRDRGWPVDDLL
SVSRLEGWGNVCDAGGFITNAASFDPAFYGITQREALASDPQQRVGVRVAWKALENAGIN
PGSLDGAEVGCFFGTSPSEYGPRGGEANEHTGYRIVGAGQLGVAARVSHGLGLTGPSMCV
DSACASSLSALQLAASSVRAGECEWALAGAVCVMGSPGAFYEFAKLHALAADGHCRSYAD
DASGTLWGEGAGVVVLERESRARSLGHRIFGRIMAIRTNHNGKGKPILVPRSGAQAKLVA
ATIAASGVDPADVGMIEGHGTATRAGDPLELIALQTTYGAGGSHALLGSAKSNAGHAQAA
AGMIGLIKLLLSGLHGQIPPTLFSDNPTTTVDWSMTGLRLATKLHPWEAKNGTRYGAVSS
FGAGGSNAHAIIAMPARSEEGEDGEDF
>A0A0H2ZR47|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium avium (strain 104)|TrEMBL
MPGTEQHLDYLKRLTADLRRTRRRVAELEGRLSEPVAVVGMACRYAGGVDSPEALWDLVI
EGRDTVSDFPVDRGWDVEGLYDPDPDAKGKMYTRQGSFLQHAGDFDAGFFGIGPSEALAM
DPQQRIMLEICWEALERAGIDPSALRGTATGVFAGVIHAGYGGEVKGELEGYGLTGSTLS
VTSGRVSYVLGLEGPAVSVDTACSSSLVAMHLAAQSLRSGECDLALAGGVTVMATPAAFV
EFSRQRALAPDGRCKVYAGAADGTSWSEGAGVLVLERLADARRLGHPVWAVLRGSAVNQD
GASNGLTAPNGPSQQRVIRAALANAGLSAVDVDVVEGHGTGTVLGDPIEAQALLATYGQD
RPADRPLWLGSIKSNIGHTSAAAGVAGVIKMVQALRHGVMPKTMHVDVPSPHVDWSAGAV
SLLTDPRPWPEHGGPRRAGVSSFGISGTNAHVIVEQAPAAAETEAAPASSTMPDAVVPWV
VSARSAEALAGQARRLLDHVTADAQASPLDVGWSLVSTRAVFEHRAVVVGRERGALATGL
AGLASGRPGPATVVGRARSTGKTVLVFPGQGSQTLGMGRQLYERFEVFAGALDEAVAVVD
EHSRLSVREVMWGADPELLQSTEFAQPALFVFEVALAALWESLGVTPDVVMGHSVGEIAA
ACVAGVLSLRDAARLVAARGALMAALPPGGVMVAVTAGESQVGPLLGGGVSIAAVNGPDA
VVLSGEQEAVAAVADRLAGSGARVHRLAVSHAFHSALMEPMLDGFAAAAAGIEPRPPRIP
LVSNLTGQLAGPGYGTPQYWVDHVRRPVRFVDGVRLAESQGAGVFLEVGPGAALTSAVEQ
SLTSDRAMSVVTMPKGRPEVDSLLTAAARLFTAGADVRWSAAFTGLHARRVDLPTYAFAR
RRFWLSGDAVGSANIASLGLAEAEHPLLGAVLDRPDSGGVVLTGRLSTAAQPWLADHAVA
GTVLFPGAGFVELALRAGDEVGCPVVEELTLSAPLSLPAGGTVQLQVVVADAAGQPGSRS
VAVYSRVAQSEWTLHAEGVLSEAAPAPAAELSVWPPADAEAVDVAGGYDDLAGRGYGYGP
AFRGLRAVWRRGAETFAEVELPEQAGVSTGRFGIHPVLLDAALHALGVADKRLETVLPFS
WQGVSLHAAGASRVRVRLAPAGAGAVSVELADASGVPVLSVRELVTRAVSAEQLAAAVAV
RSGSGELLDVAWSVIEPRNSLPDNPISEGVTVWEPAAVDGAGPAAVHAATHQALGVLQSR
LAGEAGGVLVVSTRGAVGLPGEDVADLAGAAVWGLVRSAQAEHPGRVVLVDTDGSLDLAT
VIGCGEPQLVVRDGVAYRARLRPAGRRALLELPGPPAVWRLAAGDAGTLEDLAVQEHPAA
ELAPGQVRVRVAAAGVNFRDVLVALGMYPGAAQLGAEGAGVVTEVGAGVTDVAVGDAVMG
IFGLVGSEAAVDRRLVTRVPPGWSMAQAAGIPVVFLTAYYGLSVLAGLRAGQRVLVHAAT
GGVGMAAVQLARHWGAEVFATASRGKWDTLRAMGFDDAHIADSRTLDFEQKFGAAPGGMD
VVLNSLAGEFNDASLRLLGPGGRFIEMGKTDLRDPDVVARAHPGVRYRAFDLMEAGPDRI
AAMLAEVMELFAAGALTPLPVKAFDARCAADAYRFVSAARHIGKVVLTMPDGPAGLSGGT
ALITGATGMAGAALARHLVARHRVPHLMLVGRRGEAAPGMAELAAELRGAGASVSVLSCD
VGDRDAVAAMLAQVPARYPLRSVFHAAGVLDDAVIASLTPARIDTVLRAKVDGAWNLHEL
TKDLDLSAFVVFSSMAGIVGAPGQGNYAAANSFLDALAIHRHAHGLPALSVAWGMWEEPS
AMTAHLEERDKARMSRAGLSALSTRQALDLLDDALLGEQPLVVGTRLDRAALAQHRAALP
PLLSELAGRPARRMLEHTDMVSLTGLRARLAGMNPEQRQAELVELVCGNAAAVLGHSTAD
VDPGDAFSDLGFDSLTAVELRNRLKIATGLTLSPTVIFDHPTPAALAEHLGGQLTSAGPT
PAAPAETAAPPDRSSRIDEVVSELQTLLTQPGLSPGDRAQLVTRLQSLLSTPPQPSGHPE
FPEDAFDDDIATATDSQLFAILDDEAGP
>A0A124C0Q3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MEKREKLLDYLKWVTADLHRAEARIAELESLPREPIAIIGMSCRYPGGVTSPEELWHLVT
NGVDAIGELPSDRGWDVQGSYDSDPDTPGKFYNRGGGFLADVKGFDAAFFGTSPREALAM
DPQHRLLLETSWEAIERAGIDPRSLRGSDTGVFGGVLYNGYGAGVDDPELGIEGYLMTGT
SSSVAIGRISYTLGLQGPAVTLDTACSSSPVALHLAAQSLLRDESSLALAGGAMVMANPA
FFVEFSRQRGLSPDGRCKAFSSAADGMGFAEGVGMVLLERLSNARRNGHPVLAVIRGSAM
NQDGASNGLTAPNGTAQQRVIRQALANAGLTPSDIDLVEAHGTGTRLGDPIEAQALLATY
GQAHTPQRPVRLGTLKSNIGHAQTAAGVGGVIKTVMALRHGVMPRTLHADEPTSDVDWSA
GTVELLTEALPWPDAGRPRRAAVSAFGVSGTNTHIVLEQAPEDEPDDTETGHTLPVVPWL
LSARTPEALRAQAARLVSFVESAGEVEARDVAYSLATGRTAFPHRAAVLGKDVGELVAGV
RAVADGVPGATTLHGVAGEGQTAFLFTGQGAQQAGMGRELAETFPVFASAFEEVCDGFAG
LLPGSLKDVVFGGAGLDRTEWTQPALFAYEVALFRLLASWGVTPDYVTGHSVGELTAAHV
AGVLALPDACALVAARARLMQALPEGGAMLAVQAAEDEVLPLLAGRGAEVGIAAVNGPRS
VVLSGSGDAVSSLARTLSDRGHKVSRLKVSHAFHSPLMEPMLDEFAETAGRLAFGTPVVR
MAAPASEVSTPDYWIGHVRRPVRFADQVRRLRDQGVTRFVEVGPDGVLAAMGRECVDAGF
VALQRRGRPEARTLLTGLAQAHVLGTGIDWRAVFAGTGSRRIDLPTYPFQRRPYWLAPAQ
AGTSSPVAGTSEWGYEDRWRPWEAPAAGAADGTLLVVVPTGVPAEWKEMVASGLGAAVSV
EVDAAGGEQAVVDAVAGARVRDVTAVVSLLGVGDGVAGSVPVGLAGTVWLVRALAGAGVT
APLWCLTRGAVAVGAEDEVRSPEQTALWGLGRATALELPHRWGGLVDLPERIDQEVAGRL
RAVVSGRPGGEDQVAIRPAGVFARRLVRSAPGAGRGDRTWAMRGTVLITGGTGALGAHMA
RWAVARGAEHVVLLSRRGSGAPGAVGLREELEGLGARVTVAACDAADRAGLTAVLGAIPG
EFPLTAVVHAAGVGDGDAPVGEITADGLAGLWRAKAGSAWLLHELTGELGLDLEAFVMFS
SGASSWGSAGSPGYAAANAFLDGLAGYRRSRGLAATSIAWGTWSSDGLASEELLEHLARI
GLRPMDPEPAITALERALLDGHTLLTVTDTDWRRFVPAFTAHRPSPLLADLTESRDTFAD
DATPPLLQRLAGLSPGEQHRQLLHHTHTELAATLGHDDLTGIDPGHPFKELGLDSLTAVE
LSNRLSTATGVRLSPSALFDHENLTTLVEHLHSELMGGSLAPTPAAVDFDAEIRLAADVV
PPAETAPTDPGTVFLTGATGFVGAFLLRELIRSTGAKVHCLVRAADEATAFERLRAALTG
YRLWDEIDAKRLAVVVGDLARPGLGLAPETSDALARTVDVIYHVGADVNWLKPYSALKAA
NVTGTEEVLRLATRYRSVPVHYLSSTGVFARRAPHGGALAPNDPAGPGSELPTGYTQSKY
VAERMIDIARSRGLPVTVYRADVVCGDQLNGACQTRDFIWLSLKGGLQAGALPSDADALI
GMVPVDYVTAAMVRLSQTGSAAGRTFHLQNRKPAGFREMAARLRASGYRLDDVPWADFVA
TVRADRDNALFPVIDVFSVFMKLGEASHVPVDVGGTEQALAGSGITCPEITPELLGLYAR
FFAESGYFPAFPDDGRK
>A0A1V5LX70|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Firmicutes bacterium ADurb.Bin419|TrEMBL
MNKVNLNFKNFNFTLQTGREAMEHRLAIAALNPDELILKLTAFIDREDLFSDNEKNSIYY
SHTKGEISGTAFNEEDAEVNRLAEHYYEQKDITNLAKLWISGADIKWQRMYLADENIQRI
PLPGYPFRRTEYWISKAKASVTKSKKDNSSDEEFFDYKWVELPLDASASKEEDGQLVQYV
LFCDRQGISDRFIELLETKKLKYYRIEWADALKKVGENNYTIDPYNKSDYDYVFIDIHSK
SRKSKTYVLNFWPLDYKQLPDYKLSDFDKAIKFTCTTAFNMIQSIISNDQIDNQQVWFLC
SNVQPVENQSLNLLPVALWGAAKSIILEQPNILRSIIDIGQLDEYEPQELFNEVNQDTLE
GEIVYRNKKRYVSRMVPTEVQPTNELIIAKDGTYLVTGGLGSLGLLTGKWLSEKKAGKIL
LLSRSGLDMERDDDATLKKIQMINLMKSSGAEVEVLVADVTKKAQLKKVLQKYMDKKELR
GIFHTAGVYQSDYVKDMTYLNFDSVIKAKINGTWNLHEITKNYKLDYFVQYSSGVAIWGS
ASASHYGAANYFLDIYAHYCKMAGLSATSISWGGLWENSNIAANENEEYMKTMGVKVIPS
ERGMGQLETILRSGETHKVVAPIKWDSFLPVMNFKRKNMLFEYIASSKLRDQGTGDGAFD
ENDSVSFIKAIAGLPREEMKRVIIESLAHLLKEVLGIGLSEDISSDAGFFALGLDSLTSI
DFRNKLEKKLAIEISTTSLFDYNTLELLADYILENYCASANDNLAEVSAVPAADELKPDY
LSEEELSKLDEMDNSELLEILKKEMEITN
>A0A0N1GTR9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OV320|TrEMBL
MTSAVRSEDMIIGITPFGEPDAGLALAIDRAGGLGVLDLGSGDRRTREALSRLRRASPGA
FGVRVGAHCRLTPADLEPDGPHTVILTARTNGASWPIDGLSARYRVLVEVTDLAGAREAL
GAGAHGLIARGAESGGRIGELSTFVLLQQLLAAPEVAAPVWACGGIGPRTAAAAVAGGAA
GVVLDSQLALLAESALPEPAAAALRTLDGSETVVLAGHRVLLRRGPDAPQLPEDAGAQAV
AALLGTQDPREQLLPVGQDGFLAARFAERWGDVRRTLRAVRDAVLDAVRDDTAGRALRAG
SPMSRALGTRLPLAQGPMTRVSDGAPFAAAVAADGALPFLALALADGARTRAMLAETRDA
VAGRPWGVGGLGFAPEDVRAAQLEAVRELRPTHAIIAGGRPSQAQALERDGIRTFLHVPS
PGLLRQFLEAGARRFVFEGSECGGHVGPRASFALWEAQLAVLEDWSQDHRAEDVEVFFAG
GVHDARSAAMVAALAAPLTARGAAVGVLMGTAYLFTEEAVSCGAIRPLFQRQVMTAERTT
LLESAPGHATRCVPSPFAAGYRDEETRLRAEGAGDRQIWEALERLNVGRLRLASKGVTRD
TDGSLTPVDEQRQLDEGMFMAGAVAVLRSATTTVAALHESVTTGASEHLTRRAAELGREE
TVREPAAPAPLDIAVVGMACMFPQAPDLPTFWANVVGGVDAVGEVPADRWDPAVHHGEST
PSKWGGFLPRIPFDPLRYGIPPASLGSVEPVQLLSLEAARRALEDAGYGEGGREFDRART
SVVFGAEAGSDLSNAATLRAVLPSYYGSVPAGLDDQLPRLTEDSFPGMLANVISGRIANR
LDLGGANYTVDAACASSLAAVDVACKELVGGTSDVVLCGGADLHNGINDYVLFSSVHALS
PTGRSRAFDGSADGIALGEGVACVVLKRLADAERDGDRIYGVIKGLGSSSDGRSLGLTAP
RPEGQRSALERAYRNAGVSPADVGLVEAHGTGTVVGDRTELRILSEVFGEAGAAPGGCAI
GSVKSQIGHTKCAAGLAGLIKTLLALHTGVRPPTLHVEAPNAAWDRESSPFAFHARARPW
AAPPEERLAGVSAFGFGGTNFHVVVSAHAGGVPPVRGADAWPAELFVFRGRDAAAAGRAV
DELLRAAEAEGRPWRLRDLALGAARRSDASGEPAWVAVVATDVDDLVGKLRRVSADPAEH
DPARGIHRAGPDDPRGDLGDSKVAFLFPGQGSQRTGMLADLFVTFPELRPYLELGRAHAD
TLYPPAAFDDAERDRQQAALTDTRVAQPALGVAGLAAHAVLTAAGVRPDMAAGHSYGELV
ALCAAGAVSPETLLDLSAERATAILEAAGAAGSAGSAGSAGSAGSAGSAGGDPGTMAAVA
AGADKVARALEAVRAPDSVVVANRNSPEQTVISGPSDAVADTVRLLREAGIGAKRIPVAC
AFHSPLVAGAAGRFAESLAARPVHAPEFPVWSNRTAAPYPSDADGVRTELAAQIGAPVAF
AEQVEAMYAAGARIFVEAGPGSVLTRLVGQILGDRPHRTVACEPRPGGGLHGWLDALARL
AVSGLPVRAGWLLRGRDAIDAVRTPVPKRPGWTVDGQLVRTAAGALLPGALAPARRVVEP
LERTVATVPTNPPHGVPSDRDALVSEFLRTSREMIAAQRDVLLTYFGATAGAPPAAPVAA
VPQVLQAVAQLPTAQPAVAAATAEPTGDSAPPRATGPVDVQQVVLEIISERTGYPVDMIE
PDLDLEADLSIDSIKRAEIAGELARRLGAGAGADLASMDDDDLEELAKARTAAAVTDWLT
ARLGGPAAPAPTTGPDTAGAGAAAVPGTEPGTPAQVAPEVTGEPPRRHVLRPVLLDAGAD
ASAVPSAAPSAVPSSTLSGTRWVLLGEAPEAAARLVSHGGDVAVRARDHVLTEADGPVDG
VLYLGALDGADDGPVLPDAFPVLKAALARGPRWLLAVRAAGGGTPDPRTAGLRGLFRTVA
REYPELIARVVDLSDTSPSAVADAVVAEAVAPDRTPVVLRTAAGRYGFELVEAPLGALGS
TGAGPAGDGAAEAAALGLDRDSVVLLAGGARGITAQFAAALARAARCRLELLGRTPAPDG
PEAADTAAARTPAELRAALAARGGGKPTEINRAAELLLAQREITATLAELTALGGRPRYR
SVDFREPGAVLQAVKEIHAEHGRLDGVVHAAGVIEDRLVAEKSAESFQRVYGTKATGADA
LLTALEELPAAPAFTVLFGSISAVLGNRGQVDYAAANDALETLGAAFAARTGHRAVTVHW
GPWAPAAGHAGMVGVELAREYARRGIRLIDPEEGTAALLRELAWGEESATAVVHTASGW
>B9PYE4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii (strain ATCC 50861 / VEG)|TrEMBL
MMTRLPLCQQQAPPSLAGCHMLAAFQDIPERPLNRDLKELWAAYGENPFGNVLECWNRSI
PDEDAVVWLNSDGEISETTTFSELFSRITRLSSFLRAAGLQVGDRIILCYPPGTDFVTAF
FACITSGFVAVPVYPPDPSKGLSDVPRFCDINEIAGCKTALTNSLYKRVVQVITTVAKDS
RWRSVHWVCTDDVIKRHAEEAKNSVGPDFPNLSPHHPAFLQFTSGSTGNPKGVIVTHGSL
LHNCHLCWSAYQFPSHYENDGDDENITNHDFALVNQREFWRRRQEISIKSRGHRLRAFSW
LPVYHDMGLIGFVCSPILCGATLYQMSPIDFIRRPWLWLQGMSKYDCICCAAPNFAFEVV
TRKMPDNVYEHLDLSRVCGFLSGAEPIRASTIDRFCEKFGPKGVRRCAVCPAYGLAESTL
IVTARKTFQTVPKLLIVDSFQLQHEKTVVALKPEATVTMDSEEYQVLVGCGVPLEGVQVR
IVDPETKKELPPGKVGEIVVYSSSVARGYFGRPDTTKETFCYSFTDLQGKQTPPLGMRTG
DGGFMYEGELFVAARLKDLIIIRGRNFYPQDIEEAVDKVAMVRPGSSAAFAIEVDGHEAL
AVAAEVRLEEGIKGLWLRVKRQFDRSHYEQIVRDISKSVAANTGLTIHRIWLLRPRTIPK
TSSGKVRRSLTKEKLVSGKLEGILLDHAHHQHQAFYHDGPGGSRSRTRTGSGATPSGGAA
TRDGTASSNPSGDAHPKNSNTSNSITDSSHSVQRGSLRGDACVAGGRLGPSASHGGVHHE
KDHKHRGDGSGMSSPDQVPGAGAAASESSAHVALTEKVKQTVFEAAKTVLGSSEIPEIDA
PLHELGVDSIGAVEFSELISAELQVDVEPTLLFNYPTLSDVIDFFVRELEGKGSEDLAVS
LEKTGARETTTAIIGAACNLPGGTTSLNAFWDLLMCGVDAIAEVPRSRWDVEEYFDPDPG
ADGKAYVREGGFIEDAEMFDAAFFRISPSEAKSMDPQQRLLLEVAYESLYDSGYTREGLQ
RASVGVFVGCCSNDWYQVCSQLELGISSYTTTSYAPSIIANRLSYTFGLLGPSMTIDTAC
SSSLVALHIAAQELQGGSCMSAVVAGVNLMLSPHITVAFCKSRMLAPDARCKTFDASANG
YVRGEGLGSIVMKRLSQAEKDDDRILCILRGTAVNHGGRSASLTAPSGPSQQRVIRTALR
QAELTPGDIYFVETHGTGTSLGDPIEVGALKSVFGASRDAKTKPLILGAAKTNIGHLEGA
AGIAGVLKAMLALRYKHIPPNLHFKQMNPHIDVREFNVVVPTAPMAFPREDGGRLFAGVS
SFGFGGANGHVILQEALQQPSGDKPPCKRHSKRSIICFMFTGEGYEVSCMGRHLYETDDV
FKEIITKCNDILKRWLNVSLLSILYPPADKKMEMDKMMCQARFGHTALFAFEYALAESMV
SKGVKPDVVFGVGLGELVAAAFSGVMSLEEALYVVTQRAKLIDNLPPFEGVMVACRVSEQ
EVEMALSEMEINSRQSISIAAVYGRKNLILSGEQSEIDNVLMKLNIAGRWKYLPVHNVLT
MNLVSDIIPPFTHLMSTVKLCRPKVRLVSSTTGEFVDKEALSGRFWSRQVSQTVQLQQAV
GNIVASGCSLFVEIGPQVVLTKLAQQSLNGNAKDVTWVPAYDTTSDDVRVFENAVMTCNE
AIKIIGKERSLEEGQHGQEELIFHRKPFPWTEIPHPFLSGHKFTEKDDVVFENAFPRRAI
PLIADHAVNGTAMMPGAGMLEMVGAAALALDLRTTSGAVSLENISFERPMLIGAHRVTYE
YNRRHSLGEGGGAGTSPRTVRTPRLVNHAYTRLGFREKSAEKAISETAGPASTEGGRTPV
AGHHHGSYTKAGVLEDIKDYAHNVLRRAAQHAEEIDVHTPVPPSMAPPSIVARHPREGSY
GSMSRTSGIMGSNDRGDGLTVPLSVEMAIRCRVTKMKEVELSTVWDDEVTDHCFATIVIA
DKKQETYSSLQEVRCRCTERMDVNEYYDMLYDAGLQYGPRFRTIQELYRGEKEALARVHF
VGNVKQDPFESGFLIHPAVLDGALQAAGCLLEQSHSGNKVMVPVSVGSATLTKVEVFQPC
WAHVRLEETKSKAATLNVTIYDEVTREVVASLQNAVLRQVDPSASVVATIPKDLLWKVNW
QLVVEGDKEVVGRTPKVLFIGGNIELSEALENAMGSTCKTLSVDALPREKAELQKVLDAE
QWQAIVYVEAVTAGVYDALDVMNAAVRLVQAHYLNLNSGKAVGALWFVTRDTVFRDNGAD
KPGVEIPAHAGLWGLAKAARLEMEVSAGSPISMGCLDVSGADVSSMAQQILHALKSKVLT
MRETEVAVREDGLYVSRLAPQTEVDVRGAIEFHMPERGAISNLVLRPQAFASRLPPEDGQ
IELRVRAVGLNFRDVLNVMGLYPGDPGPPGADCAGVVVAVGDNVEHIEVGDCVFGVAQGC
LRTYVTTDSQLLRRMPESMTFEQAAALPVVATTVEYALHDLAKVKAGDKVLIHAVTGGVG
LVAVQLCKRVGATVYGTCSGGKKDAFAKSMGVQYVSSSRDAKAFAEDMRTFLGEDGKVDV
VLNCLIDDFIPESLKLLGPYGRFMELGKRGVWSKEKVAAERPDVQYELIAVDEMMEKDPI
WFGGMLVRVRGLVAEQKIQPLPMHVFDLADTGENGGVAAFRFMQRAQHMGKVVLKIPSPV
EEASKNGSIVITGGLGALGMVVAGWLAEEGARHICLLSRREEAPQPGEIPGWDWLRTINC
DVQFFSCDVSKYDSIRSVLRTIQTSVAPITGIIHTAGALADALLDSQTPELMKKVYNGKV
QGAWNLNRALEELGLNEQLKLCVFFSSVTSLFGNFGQANYCSANACLDALAQWRRAKGLC
CQSIQWGPWIEQGMAAELKQQVERNGMKGISNEVGLRVLHDAIRQQEKATPVIGCQAIKW
KLFMHRYIEQPPFFTNIEMDLQVTSHDSNTVLRNLPPSERRDYIKAQVAAAARQVLGSSS
PPPFDTPLQDVGVDSLGAVEFRNVLSKKLGVKLSATTLFDYPTLNAIIDHLCEVFGESSQ
KDNLSTKLGALSENDLVQEGMAIVSMSCRLPGNSTCPDLFWDMLMRCTDCVCDIPLTRWN
AEEVYSEDPDLPGKCYTRRGAFIENAEYFDNSFFGISPSEVKHMDPQQRLLLEVAYEAFA
GAGLTKEKLLGANIGVFVGACNHDWTYLIQEDKISAYTGTGSAGSVIANRVSYCLGLRGP
SVPVDTACSSSLVAADFAFEKLMLRDCTMALVTGVNLMLTPHLFIAFSKARMLSPDCKCK
TFDASADGYVRGEGAGAVLMLPYADAKAKQMTIQAVVKGTACNHVGRSASLTAPNGPSQA
EVIRMALRRAGMKPNDLKFMESHGTGTSLGDPIEVNAVRTVFAPGREKTKPLLIGAVKTN
IGHLEGSSGIAGLIKACLVLSRREIPPNLHFKTLNPHINIEDFPVQFVTDFVSLDSVEST
RKKNTAGVSSFGFGGVNAHVLLEEATRDQNATRKEENRPKICFMFTGQGSQYVGMGRHLY
EKEPVFREAITRCVEIAKEYLPLPLLSVIYPSPDERDKMQEAINETLYSQPAVFVISYAL
LELWKSRGVEPDMVMGHSLGEYIAAVCSGVISIQDGLKLVLKRAQIMSRAPSRNGVMVAC
RATAEQVEEAIHTLFGDGEKNVALASVNGLKSVIVSGNQQDVQAVLRQLGAASRAKMLRV
SHAFHSPLVKDTVAPFKRVLETVRLSKPRVMFVSTVTGKVARDELQNTNYWAEHITKVVR
FCDAVQACIAQGAKIMVEVGPRPTLSNMGKGCLPQTTADEVQWINSLEPETLSSAVFDSL
SALAKAGSGAMPAVFDRKFFPWTETCHPLLGGKNTRPDGSVVYSALLRDLVKALFLDHVV
YGKALLPATCLIEMMASATTHMISNHDEEKLVALSQVVFEKPLLVPDETSLSVLVTVETR
GQVRVASQVSNSEEEAEDHAVCQVNIVDALPAAPALTEIRARCKTEIEASQLYAQLHNVG
LQYGPRFQTIVKVFKGEDEVLGLLQAQNVTNFETGFMMHPAVLDGALQLSAVLAFEKGSS
RAMVPFGVDTVLLKSCPPDKELWARVVMNRKGVSSASATVHLYDFDGEPIAVLMGVTLRP
IEFNTAADIPRELLWEVEWESAGSYSMPQDGSLATPSGTDDSGAEDVTRTPSPLVTGENE
NTPSREVPSALPGLSTETPRASKPLSTDETSGAVLNKSVHSVLLVDYAGGHREVVASIRD
TCDVEVEVLSKPGSPELYAQQLRQFAEVVATKTETVPLSTILFLALDEATPAEQLAGGLL
ETVKVFAVEKFKKLPCIWVLTSGAQGPTRSVVSPKHAGLWGLMRTVRLELEMQIGKMVRF
GCVDLDKNLEVSVALHFILQKRTEEPFEAEMILRCPSEDSEKEPGTAEVVNRRERSASFV
SVGPEPVVPSTTDASAKSSVTSDRMALTPGALSCFDETANSTEKLIFNAFCPRLHRSPIP
VRGAVELHMPERGAISNLVLRPQAFASRTAPQSHECEIRVRAIGLNFRDVLNVMGLYPGD
PGPPGADCAGTVVAVGSGVRHLKVGDSVYGIAQGCLRTYVTTNGNLMRRMPESLTFEQSA
ALPVVAATVEYALHDLAKVKEGDKVLIHAVTGGVGLAALQFCKRVGATVYGTCSGGKKAA
YAKSLGVKYLTSSRDASAFAEDMREFLGEEEKIDVVLNSLIDNFIPESVKLLAPGGRFME
LGKRGIWTKAQMAAERPDVYYETIAVDTMMQEDTVWFGGMLDRIRDHVDSGNIPPLPLHV
FEMTDPLAGGVAAFRFMQRAQHIGKVVIRIASDLEVKIPSTTEPAATETAMLAEAGTQGN
ASIGTSTQQIADRTYLITGGMGGLGLVVAQWLVEEGARHIVLLSRRGEPSDTVKQSSIWE
YLTEKERTCVSVLPLKCDVSVKDDIVSAVKEIEARGFPPIRGIFHAAGVTADASLANQTR
EAIEQVYLPKVTGAWNLHEVCESMGLDKNLDMFVMFSSVAALLGNFGQANYSAANACLDA
LAEYRRARGLCAQSIQWGPWIEQGMAADLRQALDKVGMRGISNELGTRVLSEVVRNPRRA
TTVLCQSVIWKKFLQRYERVPPLFKNTRAGQGATADSSLMLRTMTAEERRAYVEKTVREV
VKQALGLADSPPMDLPMQELGIDSIGAVELRNALSSRLGVKMPATAMFDYPTLDAMVDYI
NSTLAEQCAGTEQDVSAETQMNLVPQIMHRLEGNIAVTSVAVHLPGSVHNAEEFWDMMHQ
MRDCITEVPLTRWNMYTFFDPDPDTLDTSYAKLGGFIEDADMFDNTCFNISPAEVRVMDP
QQRIILEVAYEAMVSAGYTSSGQASQQSIGCFIGCCNADWHMLDVPSGPFTGTGSSTSII
SNRISYTLGLRGPSLTVDTACSSSLVAMDNAMCKIIEGSCSAALVGGVNLMLSPHLFICF
SKARMLSPDCRCRTFDHRANGYARGEGAGAVFLKPLQAARKDDSTILAVVRGSAINHDGR
SASLTAPNGPAQQAVIRAALQSGGVKPADITVLESHGTGTQLGDPIEVGAIKAVFMHHRG
ADNPIYIGALKTNIGHLEGAAGIASFIKLVLCLRRRELPANLHFQQLNPHIDMTDFSAVF
PKATVDLPVTRKLFAGVSSFGFGGANAHVVIEEHFELSNAAEAPQKQTAPVKRERRSFPW
YQAFHPMLGHETKTEVDERKIDMEIRRDVFDLLAQHMVEGRPVMPAACYLETLTSAACTS
EFLHPCSRKMLRPNHHAAVTLEDIEFQRPMILEAPEGHGHQIFQILTASLGPNGNASISS
LKTGDEEQFIHATCRLSSVNDTTAFTRTPEENLKFLDEDTNRVPVDVGEMYEKLWKNGLM
LGPQFRTIHSIECSPRTAKVKLQLPQTPTSCELGFRMHPCVLDGTFQTVGPLVLAHDEQA
RKDGSSSNVGTMKLMIPFMIQRITLTSMHGVSNALWAHVALVKRESNQAIVNIDIMSMTG
EPVCCLKELTMRRLDPVPVAEIPRELTWTVDWEEGQNVDPVPANAVEVVAIDPLGMQHTV
IKELKQKGFASVQVFERDSSVEEVLRVLRISSSGDSPTSLTPASAAAGEAAKSTSLPHRV
VLFLGTGGANDAIEALDCLLQLSSGLEKAAKEDRQQEFYPIWILTKGSQSHRDKGRVSNP
VHAGLWGFARTARLEISAQTSKEASIGCVDLGPECRVADVVQHLAAIQSQEKYEREILFD
EVEEVEDQKREKGKPPSGSKRLKHFVSRLARSPLNVRGALELHMSDRGSITNLTLRPQSY
AARVTPKGDMVELRVRAVGLNFRDVLNVMNLYPGDPGPPGSDCAGTVVAVGDRVKHLKVG
DSVYGVAPGCLKTYVTTNSQIIRKMPASMSFEEAAALPVVATTVEYVLNDLAKVRAGEKV
LIHAVSGGVGIAAVQFCKRVGAVVYGTCSSEKKREFVESLGVKYVASSRDPEKFTAEMKT
FLGEEGRVDVVLNSLIDKFIPASLALLGKDGRFIELGKRGIWTHEQMRAQRPDVYYEAVA
IDVMISENPRWFGIMLDRVRTLVERKQLLSLPLTVFNMNDPNEGGVAAFRFMQKAQHVGK
VVVAIPSALDFERSTVGPPTTPQKTYVITGGMGGLGLVVAQWLVEEGARHIVLLSRRGEP
SDTVKQSSIWEYLTEKERTCVSVLPLKCDVSVKDDIVSAVKEIEARGFPPIRGIFHAAGV
TADASLANQTREAIEQVYLPKVTGAWNLHEVCESMGLDKNLDMFVMFSSVAALLGNFGQA
NYSAANACLDALAEYRRARGLCAQSIQWGPWIEQGMAADLKALAEKAGLRGISNELGIRV
LVEAVRNSKTVVTFLAQSFIWKRFVQRFDVVPPFFSNIEFETASPGAFRVLYSSMTPDEL
HTYVSNVVLDTARQVLGTSELPALDSPLQELGIDSLGAVELRNSLSQRLGVKLSATTLFD
YPTIRAIIDYIVNQVSGEASAAKATSGALVSAGLAAGRNSPIAVVGYSCRLPQGSETPDK
LWEMLRRAQDCVVEVPLTRFDVDMFYDSDIDAKGKMYVRKACFMDDADMFDNSFFNISAA
EVTYMDPQQRVMLEVAYDAFYSAAYSREHLIGKNYGVWIGCCNSDWHFLEQQSNPDKSSS
YSGPGGSGCLVSNRLSYVFGLKGPSMTIDTACSSSLVAADCGAQAMRFGYCDGALIGGVN
LMLSPQLFLAFCKARMLSPDCRCATFDEKANGYVRGEGAGAIMLRHLADAQREGKRILGI
VRGTAVNHDGRSASLTAPNGPAQQDVIRSALQIGGVDPLDVALVESHGTGTALGDPIEMG
AIKAVYGAGRSADSPLVVGALKSYIGHLEGSSGIAGILKVLLCLRHHEVPPNLHFDTPNP
HMDLSDFHVVLPKKQMKLQPAQKSSTILGSVSSFGFGGANAHVVFEEYPEPTMATDVGGE
RRSTEAAESAGKKRLAFLFTGQGSQYPNMCKQLYEEEPVFRSHMDACFTVLEGKLDVKLR
DVIYPTAENDVEMLNLLNQTGYSQPAIFCVEYALAQLMISKGFSPSVVMGHSLGEYAAAA
IAGVMDWKDALLLVHERASIMQHIDPNDGVMYACRASEQDAQAAVEKALGEKAVAVTVSA
INGPRSIVLAGTQPDVLAVLKAMDMQSRAKQLTVSHAFHCPLVGEAAALLLPKVESVKLS
NPNEGITFISTVTGKAVGAGELTKPEYWATHITKPVQFLQGMRAAVTSGEAGIFIEIGPR
PTLVNMGQQCVPRNDYTWVAPVDPKDSNRNSFPQALEKITSNMVCTYTWKRHAFPWTVVV
HPFVDKFVPDQDETKATSQKLLTPAVGELLHDHVVNGTAMMPGVGFLEAMAAGGFMMVDG
KLPSTVVALRDCEFERPMLIPKIDPSTGEFTQAAKLMITVNNKDITLKSIMDGEEEEIFH
SRCTFSLCPATSLPTEPADLLTSLQGRITTPVPITTLYETLQSVGLQYGARFQSIRECYA
AASDEVLAKLRPKLPLHSFERNFRIHPVLLDGALQTAAVLFAEMGHKRPLVPVGVKRALL
ARVPAGSEVWSHVVVKSKDLRSATMDVTLFSTKGTILGQLVDVAVRAFDAVAGAQIPKGL
LWEVSWVPKAKAPVEDGVDTVENEASETITPTAKLAVKPTGKVEGLARQPAVNGQPKWLL
LKTPSSMLEGLQKALQGTPSAFVKELDEKHPNNAISSKIHNSEWDAIIYLGALSAAASST
TCVADALLLANTLGNTAAEKPLPNVLFVTQGQHFIRECGDVPTTAVPTQTGLYGFCRSAQ
LELENIIGRPVYLGTLDFAAKDPTLDDPAAFVSALQRVLAEADPTGAAGTCEPHTVIRGG
KEMVPRLVKSSIECRGAVELHMSDRGALSMLKLRPMPKSARVPPPRDCVEIRVRAVGLNF
RDVLNVMGLYPGDPGPPGADCAGTVVAVGEGVEHLRVGDAVFGIAQGALKTFVTTSAHLV
RPLPGRLTFEQAAALPVVASTVEYALHDVAKVKKGDKVLIHAVTGGVGLAAVQFCKRVGA
EIYGTCSGGKKEEFARSVGVKYITSSRDPKKFAEDMCEFLGNGKHKIDVVLNCLIENYIP
ETLKFLAPNGRFVELGKRGIWTREQMGTVRPDVLYETVAIDTMMEEDPVWFGGMLDRIRN
LVDGSMLQPLPLHTFEMTDSSEGGVAAFRFLQRAQHIGKVVIRLSSALEVKNFTTNSRQE
TENEDSGERHTLSPATAVGKPLSQSVADQMHKTYIITGGTGGLGLVVAQWLIEEGAHNIV
LLSRRGEPPSSVKAGDPVWKYLCGEEQPNCISVATLKCDVSQKDDLLRVFKEIESRGLPP
VAGIFHAAGVTADAALASQTADSVDQVYLPKAIGAWNLHDACEALGLNKSLEVFMMFSSV
AALLGNFGQANYSAANACLDALAMYRQSLGLCGQSIQWGPWIEQGMAAQLTQHLEKVGMR
GITNELGLRVLGDVMMHPTVAVVGAQSLQWRKFLRRYAFEMPSFFSLVPMAGAGSSEASV
NLATITKEDLCELISSLAQAVSGAAEKPAVDTPLMDLGLDSLGAVEFRNSVADKVGVKLP
QNLMFENPSISSISDYILDKAAGKHGESGVTGANGGSGEGSDIPALDTPLDQWLMSVLEP
AERFALYIDSFASEYGTLQKMAAEEDIITALEDLGVEDGGDFERLHVAWDDLCNQINTAK
RMAAKDIRPSSTAVSVSDHPKPRMPHPMEDVDTLLASLDFDVSTLRPATAPDKVKNVLLT
GVTGFVGRVQLASLMQLKQRPDLRVYCLVRARNADHALSRIREATKEAKCWQETFVSRIV
PVTGDFTQPLLGLSSEEFQELARKIDIVYHTGGDVNLLSNYGRLRATNVLSVKAIIDLCT
TYKVKPLHFASTLGQFPAFFAMFTGHFSGESIREDSTPDVSQMENFYPPSRQGYPWSKWA
AERVLEGARKRGLPVAIYRLPNTYVAYKTGYTNKTDYATALMIASIQEGVFPIGAATAPL
TPVDTICDMLVEASFLEKPKHWVYHLFDPRLVTRADLEQWSQELGISYVGVKVDEFLEAI
KKRGPESPVFKFVPLMQHWRRFWFDPEERTESFPISNEHIFEDLPHMRWPSLREVFKNSL
LYSVRMGFFPKNSKSIILDPQVALNEARRICGLQLMGREGEDFFLHPWRVLQESARRECD
LLFGGQLAVYRTVRHYFMNVMYLADAQAKCPEIEKQEIQAPLIIVGLNRTGTTFLQNLMS
TDPSNRSLRYCEMIAPYGPDGNYRPKGLPNTEESWKKDPRIPFAQEILDSQLGLSEEWMA
IHTQRAELPEEDFVIFEHCGRCYSICTEFSVPSYREWLASDNYKETRKAYSFHKRFLQHL
QWQRPAKRWLLKMPFHLFTLEALFETYPDAKIIFMHRDPKETMGSWASLVKHAQQSLMDN
VDPSALGREELRAMSTMINRALAFRRSHPELGPRFLDVQYQDLVNNPIGVVKSIYKHFGI
PLTLAAQTGIASFCNENRKHRDKLTKHMYSLKDVDLTDGMVQEAFKEYYDSGLCKYLSSA
R
>A0A3S4I762|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Citrobacter koseri|TrEMBL
MREITQPMRLFDFVFGPLVLPLQDLDAREGELFLTTAQWQQQCRHAGFSKVAWLPQDGSP
TAGMSEHIILATLPGQAVSAVTFTAPSEPVLGQALTDNGDYLADWSDCAGQPERFNARWQ
EAWRLLLTASWRRSACGTALVAAPEWLGEVRLSWQNEAFSRGQMRVEARYPDGEWLPLSP
AAPLPAPQTHYQWRWTPLNVASVDHPLTFSFSAGTLARSDELAQYGIIHDPHASSRLMIV
EESEDTLALAEKVIAALTASAAGLIVVTRRAWRVEDNEALSASHHALWALLRVAANEQPE
RLLAAIDLAENTPWETLHQGLSAVSQSQRWLAARGDTLWLPSLAPNTGCAAELPANVFTG
DNRWHLVTGAFGGLGRLAVNWLREKGARRIALLAPRVDESWLRDVEGGQTRVCRCDVGDA
GQLATVLDDLAANGGIAGAIHAAGVLADAPLQELDDHQLAAVFAVKAQAASQLLQTLRNH
DGRYLILYSSAAATLGAPGQSAHALACGYLDGLAQQFSTLDAPKTLSVAWGAWGESGRAA
TPEMLATLASRGMGRVKRCRRLLAPGTGGDARCPVATGDARFYRQNAPITTGSV
>A0A447GFD0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium basiliense|TrEMBL
MKHPADSAAALAESTTAGDSSGIAIVGMACRLPGAPHLSRLWPLLRDEMDATVAVPPQRP
LGIDRAGLIDDCGEFDAEFFGISPREAESMDPQQGLALELCWEGIEDAGLVIDSASTLPV
GVYLGVMANDFADAMAAIPEKDITHHLHTGIGRSMIANRVSFALSLSGPSFTVDSGQSSS
LVAVHLACESLRRRECEVAIAGGVNLMLAPFSSYRTAKFDALSPDGRCYVFDERANGYVR
GEGGGVVVLKPLADAVASGDRIYGVIRGSAVNTGGEWGGITIPVQAVQEEAISIALATAG
MSPSEIGYVELHGSGTPVGDPVEAAALGAIYGSAREPGDTLRVGSIKTNIGHLEGAAGIA
GLIKAALCVQKQELVASLNFVTENPRIPLESLRLKVVTEYERWPATGGPLCAGVSSFGMG
GSNCHVILAPPPDCRQIDSAPVVPTPVGLAMPLLLSATNEAALREQAERLRAYLAANLHI
PVADAGFTLATKRFWCDFRARVVGSDRDQLLAGLSALAAGRSDTAVAYGHVVDGKTVFVF
PGQGAQWEHMAVDLWDSSPVFAAQMTACAEALAPHVDWSLEQVLRGGAEEASLARVDVVQ
PVLFAVMVSLAALWRSYGVQPDFVIGHSQGEIAAAYVAGGLSLADAARVVALRSKAIAEL
GSAGGMASVGLPAEQVTARLEPWAGRISVAAHNSPTSTVVSGDATALQEFVTTCEGEDIF
ARLIPVDYASHSAHVESVRDRLLAELSSITPRVGDIPFHSTVTGTQMDTAVLDAGYWYRN
LREPVQFADTTRTLIEDGSRTFIEMSPHPVLAVPIRATAEALGQDSASVAVLGSLRRDEG
DWPRFLTALTDAYVAGLRVDWPAVFTPYEPRQVDLPTYAFQRQRYWLGVRTAGATGLESV
GLSGVGHPFLGAAVGLGDARGWVFSGRLSTQAHPWLADHVVLDVVLVPGTVYVEMAMAAG
AYAGLDLLEELVLEAPLVIPEGVAMQSQLLLGGPDEHGRCRFSIYSRPDVDEDTEWIRHG
TGVLGTGGDHDDAEFQRLSAEWPPAEAQPVPIDSLYDRFAETGFRYGPAFQGVRAVWRLG
DELFAEIALGSEQLGQAASFVLHPALFDAALHPFPAWLGDEEPGRVPVTCAWNGVSLSSN
GTSVLRVALLPKGKFGLRLNAVDEFGSPVVRVNSLTLRSVDAGHLGRGDALRLSWLHRVS
WVPVEGAVAGVNPRMAVIDNLQQADLSAVFGEGVDHYPNPAALAEAIREGAKAPEVVLAA
APFAVDGLEGVDQLSQQTRAALSDSLELVGAWLGEPELTPCKLVLVTHNAVAAHDSEVPD
LASAAAHGLLYSAATAHPNRFMVLDVDDIIHCRQTVAAALSLTEEPRLAARKGALFAPRL
LRVPARPPLTTGKVFGPEASVLIVGGPSALHTTVGPHLAVRHGCTHLILLSPQDAIEAEA
DELRNTVAEFGCRVDYVSCDVTDRDQIAAAIAEIRAKHRIGAVIHAAGVWANGTVGALDR
EGIAEVVGPKLDSALYLHELTADIDLSAFVLCSAAAGVLGSPGEGRFAAESAFLDALAAD
RRQRGLAATSLAGGLWGGPQGITGPSGVGLRTHMQRLGLAMMSTEDGMELFDLACERPEP
ALVPARLDIGALHAQARLGTLPALLSRLIRIPARRQRPTASFVQRLAELSDTEWDRVLLA
EVCAQAAAVLHCSVDTIKATRAFNEIGLESLDAVELRDCLTQTTGLKLPSTLIFDYPTPA
ALAGYLRTRLDGTISTVSTPTVPDPTNEPIAIVGMGCRFPGGVHSPTGLWDMLANSRDVI
SQFPTDRGWDLEHLYDPDPDQVGCVYNRGGGFVYDAGDFDAGFFGISAREALAMDPQQRL
LLECSWETLESAGIDPQSLHGSQTGVFAGVMSSQYGINGGPDAEVEGYLLTGSSSSVVSG
RVAYVLGLEGPAVSVDTACSSSLVALHEACQSLRSGECDLALAGGVTVMATPSLLIEFSR
QRGLSVDGRCKPFAAGADGTGFSEGAGMVVLERLSDAHRLGHEVLAVVRGSAVNQDGASN
GLTAPNGPSQQRVIRAALANAGLSPAEVDALEAHGTGTVLGDPIEAQAILATYGQDRDPQ
RPLWLGSIKSNMGHTQAAAGIAGVIKMIQAMRHTTLPASLHIDQPSPHVDWSSGHVQLLT
EPRPWHTNNHPRRAGVSSFGISGTNAHIILEEPTTTTQTPPTTEQPTPNKSALLPWVLSA
KSAAALTHQAQRLVNFLTTNPQPHPHDVGWTLTQRSTFDHRAVILGTDQHTLLTGLTALA
NNQPTTNLTVGQALPTTKTVMVFPGQGSQWLGMGTHSMTSCRCSHRPSMRSLRPSTRIYG
CRYVKCSGTDTGLLDSTEFPTSTFAVETALFTVLQHWGLTADFVMVIRGEFSAAYAAGVL
SLNDAAMLVAARGRLMQTLPTGGAMIAINATTEEIEPLLPTGVAIAAINAPDSIVISGHQ
AAVHAIAEQMTTQGRRTRRLAVSTRFTPR
>I8U1X2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pelosinus fermentans JBW45|TrEMBL
MKAASTGITKTSQEIQSWLVSQMAERLKMAKSKIDIREPLSAYGLDSAEAVTITGEMGEW
LGRDISPTLVWDYPTIDGITRFLTNTPNDSAAKDTGKQDHIAESIAIIGIGCRFPGANGP
RAFWDLLKDGVDAISERPSDYRRNQGYSEQPCITGEKMSWGGYLNNIDEFDAQFFGISPR
EAASMDPQQRLLLEVAWEALEDAGQVPERLSGQSVGVFVGISGCDYGTMLRTFSEMDIYA
ATGNAWSVAANRISYLLNFQGASLSIDTACSSSLVAVHLACKSLQNGESTLALAGGVNLL
LSPEVTEAFAKAGMLAPDGRCKTFSAEANGYVRGEGAGIVVLKSLSKALQDNDPIYALIP
GSAVNQDGRSNGLTAPNGPAQEEVLREAYRRTGISPGKIQYIEAHGTGTSLGDPIEAKAL
GKVLAAERSPQNPCLIGSAKTNIGHMEAAAGIAGLIKVALAMKHRQIPASLHFDNPNPYI
PFEELPLRVQTELGPWPDMSSSLLAGVSSFGFGGTNAHVVLESFQSTSLKKHNMMNYLPK
EKQLLPISASNQEALCDLARSYRDYISGEGKNFSLKDICYTAGARRGQHDHRLSLVVGSK
EDVVDHLEMYLKGEAFPSLQSGQRSSGASSKLVFVFSGQGPQWWAMGRELFQEEPVFRET
IEECDVLFSQHADWSLVTELTAIESMSRLDQTKFVQPALFAVQVALARLWIVWGIQPEAV
VGHSMGEVAAAYIAGALSLSDAVRVIFHRSRLMQRTTGQGKTVAVELAWEEAKSLLVNYE
NKVSIACYNGPTSLVLSGEPASIEEIMTTLEQGNIFCKALPVNYAFHSYQMEPLMSELAE
SLQGLQSQAATIPIYSTVTGQLIGGQELSVDYWVRNLRESVLFAAAVDCLVADEYNVFLE
ISPHPVLSNTVKQSISRQDRNGIVLPSLRRQEPEGAAMLNSLGHLYTLGFSVNWEQLYQE
GARCVSLPTYPWQREQYWFEMKKNTLMYPIPQHTVSDELDRWLYKLEWQPKELSREDRVV
SDKKGKKTWLIFAQQEGIGDLVAKGLTERGERTVLIYPGQSFQCLSEDTFSINSSQEDLK
QLLHTVLNPALDVCHGIIHTWSIGSNDKNNITTVDLEKAQNLGCLHVLQLIQIIQELKIN
GNRALPRLWLITRGSQAVLEEGEPVDFIQAPLWGLGRTIAIEQKELWGGLIDLDPEDQGE
QAADMLLEDIFVQGGEDQVAYRQKTRYVARLKRHSLSYDRNNPFYWQRNGTYLITGGLGD
LGMQVARWMVEQGARRLILMGRTELPPRTAWDSVLESEDRLSHQIGTIKELESMGASVHL
AAVDVADEEQLKNFLVSFREEGWPPIRGVVHAAGTVADQLLTECDSGSFNKVLRPKVQGA
WQLHQLLKDVPLDFFIVFSSISTVVSSPRLGSYAAANAFLDALMHYRRNLNLPALSINWG
PWAEIGMAARFNILSSTTSMGINALTPACGLQILDNLINTDMTQIVVMDVDWERWRIIYQ
QIGKSELVADLLLEESEAAGTVSNAINQESSIRKELIEANEGEHYNLLESYLCEQVSQVL
GMSKAKLDVHTSLNSLGLDSIMAVELKNRIEKALDVMVPMVYFLQGPSIAEMIAKIQELL
IVDAGISGIPIAPEQEYYPVSSAQKRMFILNQFETKETVYNNFVAFKVEGALNKHQFENV
LNRLIQRHETLRTSFEIIDGEPVQRIHQEMEFAIEFIQGQKEDISGIIQDFARPFDLNKA
PLFRVGLVEMAENEHVVLFDMHHIISDGVTAEIFIKELASLYEGQELPELRVQYKDFALW
QNSAFQREALKQQEAYWLKAFAGELPVINMPRDYPRPLVRSFEGEVLRFTLGEEVTGELN
KLAMETGTTLYMVLLAAYNVVLSKYTGQEDIIVGSPIAGRQYADLHNIIGVFVNTLAMRN
YPEKNKSFLEFLQAVKENALKAYENQDYQFEELVDKLDIPRNLSRNPLFDTMFALQNVDI
AELSIGNLRFSRYEFDNKIAKFDLTLEAIERSSQLDFTLEYDTKLFKKETMERLSRHVEN
VLNSIVEQPQIKLADIELVSKEETCQILLDFNNTKTAYPKEKTIQELFEEQVEKNPHHIA
VVFEEQQLTYQELNNKANQLARVLRKKGVEKSRIVGMMVERSPEMIIGIMGVLKAGGAYL
PIDPEYPEERVSYILEDSGTGILITHKYLAAGITFNGDIIDVDDSELYQGDATNLTKENT
SQDLAYVIYTSGSTGKPKGNLTMHHNVVRVVKNTNYIEINEKDVLLQLSNYAFDGSVFDI
YGALLNGAKLVLVDKASILDMNRLAKVIEQEKVTVFFITTALFNTLVDVNMECLKNVRKV
LFGGEMSSARHVRKAFKYMGKGRIIHVYGPTESTVFATYYEVKHIDDGELSIPIGAPIAN
TSIYILDQGGNLQPIGAPGELCISGDGLATGYLNRPELSAEKFVADPFVQGERMYRTGDL
ARWLPDGNIEFLGRIDHQVKIRGFRIELGEIEGELLNHLSIKEALVVAKEEITGYKYLCA
YIVVTQELTVAEIKEHLIKTLPEYMIPSTFVQLDKMPLTPNGKIDRKALPEPEGKMSTGT
EYVAPRNEMEEKLATIWQDVLGVEKVGIEDNFFELGGHSLKAITLVAKIHKEFGAEVPLQ
EVFKTQTVKELVKTIKGAVQNSYAAIELAAKQEYYPVSSAQKRMFILNQFEAKDTAYNMP
AAFKVEGSLDKERFEQALQKLVQRHETLRTSFEFINGEPVQRVHEECNFTMNYREGANQD
ILNIFQTFIRPFDLGKAPLLRVNLVELSTKNYVVLFDMHHIISDGVSVGILVKELASLYE
GQELPELKIQYKDFSAWQNNLLVTESFKQQEAYWLQAFAGEIPVLNMPSDYTRPSIRSFE
GDELEFVLGEELTEALNKLAGQTGTTLYMVLLAAYNVALSKYTGQEDIIVGSPIAGRSHD
DLENIVGMFVNTLAMRNYPEGNKSFLEFLQEVKLNALSGYEHQDYQFEELVEKLDIPRDL
SRNPLFSTLFSLQNVDITELKIGELQFLAYKLDNKTAKFDLTLRAIERNNRLEFTLEYYN
KLFKQETIERFGRHFVNLLSSIVAQPENKLTRINMLAENEKRQLLVDFNNKEAVYPTDKT
ISELFEEQVRITPDHIAVTFAEQHLTYEELNNKANQLAKVLRNKGVQPNSIVGIMVERSL
GMMIGLVGILKSGGAYLPIDPEHGKERIAYMLENSQAKILITQNRFIRQAPADIGIVDLE
DENIACEESSNVSILNKPNDLAYVIYTSGTTGKPKGVMIEQRNVINLVYGLRDRVYGEYA
SVLNVALLSPYVFDASVKQIFPALLLGHHLCIVPEHIRFERAGLLNFYRKNEIDISDGTP
AHLSVFNSISKSDEYLGVKEFLIGGEALSYAVVQEFLNHFNNSPIKITNVYGPTECCDVA
TVHEVDCGENHSGDIVPIGKPISNVKVYILGEDLSVLPVNAIGEVYIGGQGVGKGYLNNP
ELTAEKFIDNPFIPGERMYRTGDLARWLSNGTIEFFGRIDHQVKIRGFRIELGEIEVQLL
NHKWIKETVVIAKEDITGQKYLCAYIVAEQEVTIAELREHLAKVVPDYMIPASFVQLEKM
PLTLNGKIDRKALPEPEGRGNTGREYVAPRNEAEEKLAKIWENVLGIEKVGIEDNFFELG
GHSLKAVTLVAKMHKEFGVEVPLTEVFKAQTVKELSKAVEGAVHTSYAAIEPIAKQQYYP
VSSAQKRMFILSQFETADTTYNMPAAFEVEGALDKDRLEKVWQKLVQRHETLRTSFEVID
GAPVQRVHEEIKFTIDLIPGTKEDIPNIIQTFVRPFDLSKAPLLRVGLVELTENLHVVLF
DMHHIVSDGVSMRILVKELTRLCEGQELPELRIQYKDFSAWQNNLLTTERFKQQEAYWLQ
AFAGELPVLNMSSDYPRPAIRSFEGDRLNFELGEELTGELNQLAMENGTTLYMVLLAAYN
VVLSKYTGQEDIIVGSPIAGRPHADLENMVGMFVNTLAMRNYPGKNKSFLEFLQEVKVNA
LMGYEHQDYQFEELVDKLDIPRNLSRNPLFDTMFALQNTDHAVLAIGNLRFSPYELDNKI
AKFDLTLEAAERNNRLEFTLEYDSKLFKPETAQRMKRHFVSVLNSVVDQPGIKLRDIELV
SEEEKRQIFVDFNNTKTVYPKDKTIQELFEEQVEKAPDHIAVIFEEQLLTYKELNNKANQ
LARVLRNKGVKNNRIIGMMVERSPEMIIGVMGILKAGGAYMPIDPDYPEERINYMLEDSK
TGILVTQQSLRKKVAFIGDIIHVDDQQLYRGDIENVVKENTAQDLAYVIYTSGSTGKPKG
NLTMHYNVARVVKNTNYIEITSEDVLLQLSNYAFDGSVFDIYGALLNGGKLVLVDKACVL
DMNRLAKVIERERVTVFFITTALFNTLVDVNIECLKKVRKVLFGGEQSSARHVRKAYEYL
GRGRIVHVYGPTETTVYATYYEINHLADSDLNIPIGAPIANTSIYILDQAGKLQPIGVPG
ELCISGDGLARGYLNRPELTAEKFVENPFAPGERMYRTGDLAKWLTDGNIEFLGRIDHQV
KIRGFRIELGEIEAELIKHPFIKEALVIAKDDVSGSKYLCAYLVSEQELANTEIREHLAR
RLPDYMIPSVLVQLDKMPLTSNGKIDRKMLPEPDGSINAGTEYVAPRNAAEEKLAKVWQE
VLGVEKVGIEDNFFELGGHSLKAITLVAKIHKEFGVEVPLQEVFKAQTIKELIKIMEGAV
ENNYVAIESVTEQEYYPVSSAQKRMFVLNQFETKDITYNMPAAFVAEGSLNREHFEQAIQ
KLAERHETLRTSFELVGGEAVQRVHQELVITIDWLQGKQENPAKIVNDFIRPFDLSKAPL
FRVGLMEMAENKYMVLFDMHHIISDGVSMGILVKELASLYDGQELPNLRIQYKDFSTWQN
NLLTSENFKKQEEYWLQTFTGEIPVLNLPSDYPRPPIRSFEGERLEFVLGEELMAELNEL
AGRTGTTLYMVLLTAYNVVLSKYSGQEDIIVGTPIAGRPHADLENIIGVFVNTLAMRNYP
EGNKTFLEFLQEVKENALAGYEHQDYQFEELVNKLDIPRSLNRNPLFDTMFTLQNVDISA
LRMGYLQFTPYELSNKTAKFDLTCQALERNNRLEFTVEYYSKLFRKETMERFGKHFINTL
KAIINEPHIRLAAIEMLADDEKQQILIDFNNTQKVYPKNKTALELFEEQVENLPRDTTAV
VFGTQRLTYQDLNRKGNQLARILENKGVKPHNIVGILTDRSPEMMVGMIGILKAGGVYLP
IDPDYPEERISYMLADSGANILLTQKHLVHKEVFHGETLLLDDENLYYGNDDNLYLKTDS
QDLAYVIYTSGSTGKPKGVEIEHASLVNLISWHRRVYNITQEDRASQLAGQAFDAAVWEI
WPYLASGAGLYIPNKETRISTNGLIRWLKDNEITISFMPTPMAEALLAEEWPLDISLRAL
LTGGDKLRRRPCRELPFTLLNHYGPTENTVVATWTSVSPDGHEDMLPSIGSPMDNAQIYI
VDRNNKLQPIGVAGELCIAGDGLARGYLNRPELTAEKFVANPFVPGKKMYRTGDLARWLP
DGNIEFLGRIDHQVKIRGFRIELGEIEIGLLNHPSIKETVVMTKDDGNDQKYLCAYIVVE
RELSVAELRKYLGGILPDYMIPLTFIQLETMPLTPNGKIDRKALPEPEERLGAGMEYAAP
RNKREETLAQIWQDVLGIEKVGIEDNFFELGGHSLKTINLAARIHKEFGVEVSLQDVFKS
QTIKELSKMIEGSVQQDYAGIERVTPQEYYPVSSAQKRMFILSQFANSGTTYNMPAALEV
EGSLDKDRFEEVWKKLIERHETLRTSFVVIAGEPVQRVHPKIDFTIDCIQGAEKDIHDII
QTFVRPFDLSKAPLLRVGLVELTEINKHIVLFDMHHIISDGVSIGILIKELASLYDRQEL
PEIKIQYKDFSSWQDNMFRTEGFKRQEAYWMQTFAGEIPVLNMPSDYSRPAVRSFEGDRL
SFSLEEELTGELRKLASQTGTTLYMVLLAAYNVLLAKHAGQEDIIVGTPIAGRPHADLEN
LVGMFVNTLPMRNHPAGEKSFLEFLQEVKEHALSAYEHQDYQFEKLVEKLDMSRELNRNP
LFDTMFALQNIEMNPLEMGTLRFIPYEWDNKTAKFDLTLYAAEGNGRLELMLEYYTKLFT
EDTAKRILNDYCKILQQVTKNKDIIIKMISLEEQYVKRKRIQQNLDFNF
>A0A1W1HKV3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Desulfamplus magnetovallimortis|TrEMBL
MIPWSEIPIHIPKAPIPWPLKQDGERVAGISSFGFSGTNTHMIISGIESVKGPSIGFIQG
KERDTKGMGAGVRKMEKGSQEMEKAPREMEKAYLFPLSARTPKALKEMARRYINGPLLQP
KNQTKENDQTRIDDHIRENGHIPKNDPEWPIICATAAQVRTEFPYRMTLVADNKKMARDI
LTDYTQDIYTDNLQITEMEQSRDISRVVFLFTGQGSQYLEMGKELYDTEPVFKKAMDQCD
EILKPHLKIPILELLYGSGNYNEELLNGDDREELLSGDKRKTILSDDEREELLNSTGYTQ
PALFAMEYALAQLWMSWGIRPSAMIGHSVGEYVAACIAGVFSLKDALYLIALRARLMQDL
PREGAMAAIFASSQVVEQAILQHNAATSHNISVAAYNAPKNTVISGKRESVESILKTFTE
WGIEYRHLPVSHAFHSELMDPILNDFHRRTLEIDYQPPRIEIISNITGKVAGTEIGTGDY
WVRHLRSPVRFADGITTLLKGSHGSFIEIGPSATLISMARQIAENQMRERVTQERAIKER
ATQQRATKKGATKKGATKKGATKESDAAPLWLPSIRRKTPPRRTILKSLGCYWANGGVVN
FGAVNHSIATVDKNLRLPTYPFEHRPYWKEVEVDSPRSTLKGLSQLDHPLLMNCFQSPLL
KSTFFETMFDQRRIPLLNDHRVFGQLVVAGATHISLISAAILVHNSFPFSLREVLFPQAL
VVPEDDAVPVQLTISTPKNNGEMDFRLISLDESGQQSALHAKGSVITNSMESINVNMEMD
STENLQAHYNKLQNINAKDITKKEITKEEIKEKLDEIRKSCQEEIPVNEVYNLQRERHIV
LGPSYQWLKSLHRGRDEVIATLAPPELVLNMDSNVMDDPSKYEIHPGLIDSCFGAMVMTR
SMEVDETFIPFSMGELHIYRAVSGIPLLIVHARLTHQDENRLIGDIEIYSQEDYMPVAKF
VALEGRKAARTALLQKSDKEHESLYKISWEKYKDHSSENQPGSKDIGSTLKMISGKDKPW
LIFTDEDGIGKATAELMEQRGIATITVKADLHGDALKQLYTNLFTINPNTHSSNTTASNI
TASNTTSSNTISSNTISSSRPFEMLFSACGPLGGIIFLWNNIKTDEKNDLGNESEITFPN
SPLQLCEREPGGEINGQVIKNPFLNHETETLLNILKSLTKVSIPIENLPGRILVTTCGSC
RATLQDTIPNPQQAALWGLSLSAAQEQPAFGLTCVDIPPDTQPDQCARYLMETIELPLTE
NRIAWRNGHAHVPRLVPVTHVIKNRSLKTDDNLIDKEKTYLITGGMGALGIKLADWLVEK
GARHLALLGRTPVSLTGDNDNSGNAYNGNTDNVYNDNNYNSDANIHNNSTHGNNPIHMAL
NELKEKSAEPIYYSVDISNGDELARIFKEISMKQPAIGGVFHLAGQLHDALIGDQTDDTL
KKVMEPKALGCWNLHGLTCDLDTLDHFVCFSSIASVLGSAGQSNYGAANAFLDALIDHRR
ALELPGLSINWGPWAEAGMAARLNPKLSEQMKNQGIYPMEPDSSMETLGRLLSMAFNDHN
MNKTHPDRISQAVVITAAWDLYTRGNEIPFLERCINKELYNNDVANDKKASLIQQLAPLS
REERRVHLNRHLQKLVGTVLRMEASDVAPRIPLFDIGIDSLMALEMKNQLQRHLETPLSA
TLLFDYPTIETLTTYFLDEALLSKLSEHKGPDAEKISDGKTNGYLDETNGYRVETARQNS
AKDSDSPGDGDEVVNIQEISDDEAEAMLLAQLEKLEDHS
>A0A0N1GK83|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MLPEDARARENTPESPEFPDSPELPPSPASLESPESSERSERPERAESANGDVARRTTQT
TYEKRGFGNSVNEQPSYESYGNGENAAHGHVDFSHAHGKPVSDKPVSENPVHGNLAHEKP
VHENAIAVVGISCRFPQAPDPAAFWRLLVEGESAVTDTPEARRGALAASNTVRRGGYLDQ
VDRFDPGFFGISPREAQAMDPQQRLVLELGWEALEEAAVLPARLRGSRTGVFVGAIWDDY
ATLARRLGPETVGRHTLSGLNRGVIANRLSYVLGLRGPSLTVDAGQSSSLLAVHLACESL
RRGESELALAGGVNLTLAPDSDLASAGLGALSPDGRCHTFDARANGYVRGEGGALVLLKP
LARALADGDRVHCVIRGSATNNDGGGDGLTAPLREAQEEVLRLAYERAATNPADVQYVEL
HGTGTPVGDPVEAAALGAVVGHDRTDGTPLLVGSVKTNIGHLEGAAGIAGLVKTVLSLRH
GRIPASLNHETPNPAIPLTDLNLKVATAPQPWPHPERPRLAGVSSFGMGGTNCHVVLEEW
PAGRPGSTSAEPAPGTASTTVAASATATAATTLPWALSARTTEALRAQAGRLLAHLRDNP
RVGPADLGLSLATTRTAFEQRAVVLAADGDGLERGLLDLAEDRVVGGVVRGADRGGAGPV
LVFPGQGAQWVGMGRELLDTAPEFARRIEECEEALAPYVDWSLTAALRGGPDAPDLDRVD
VVQPVLWAVMVSLAQLWRAYGVEPAAVVGHSQGEIAAAVVAGALTLEDGARVAALRSRAI
TAIAGDGGMMSVPLPAEDVRARLEPYGGRLSVAAVNGPGSVVVSGAADALDELFASLTGA
GVQARRVAVDYGSHSAHVEPVRERVLDALAGLRPASAEIPFFSSVTGAWLDGDTVLDAGY
WYTNLRETVRFEDAVRGLLAAGHRAFIEVSPHPVVAFGLRETIEDAGVDAVVLGTLRRDQ
GGLDRFVTSLAEAHVQGVVVDWAAVFAGAGAGSGLGLGAAGARRVDLPTYAFQRRRYWLP
EPVVGGGAGVALDGPAGGLGGPVAENELDAEAVASPLHARLARLSSRERHGALLELVRTH
AADILSHDSADDVEPRRTFKDLGFDSLTSVDLRDRLKSATALNLPSSLLFDRPTPEAVAA
YLDGQLSGTEAELALAALTPRAVDDDPIVIVGMACRFPGGVGSPEDLWRLVSEGGDAVGG
FPVDRGWDLEGLYDPEPGTPGRVYVRDGGFLHEAPLFDAGLFGISPREALAMDPQQRLLL
ETSWEVFERAGIDPAALRGSRTGVFAGAMAQDYGSRFRGTSEGADGYLLTGNTGSVISGR
IAYTFGFEGPAVTVDTACSSSLVALHLAAQALRSGECDLALAGGVTVMSTPDTFVEFSQQ
RGLAVDGRCKAFAEGADGTAWAEGVGLLLVERLSDARRNGHRVVAVVAGSAVNQDGASNG
LTAPNGPSQQRVIRQALAGAGLKAADVDAVEAHGTGTPLGDPIEAQALLATYGQDREQPL
WLGSLKSNIGHAQAAAGVGGVIKMVMAMRHGVLPRTLHAYEPSSHVDWTTGDISLLTDNV
DWPQPSDRPRRAGVSSFGISGTNAHVIVEQPPTDESDEGDEGVEGVEFGERDTAVLDAEP
RIVLLPLSAAEPRALRAQAEQLAALLASDPELPHQDVALSLATTRSALDHRAVVVAADRQ
QALRGLRAVAMQEPAGHVVTGTTVAGSGRTAFLFAGQGSQRLGMGREVYEAFPVFAAAFD
AVDAELPFGLREIVFGDDAERLNRTEFAQPALFALEVALFRLLESWGIRPDVLAGHSIGE
IAAAHVAGVWSLSDACQLVAARGRLMQALPSGGAMVAVQASEDEILPLLNDRVGIAALNG
PQSVVISGAADAVEEVVAHFRAQDRKTTALRVSHAFHSPLMEPMLAEFQAVAEQLAYERP
QLAVVSALTGELVEGAELVSPEYWVRHVREAVRFADAVGRVRAEGVGNWVELGPDGTLTA
LAQGCLDGDGQLLVPALRKDRDEVGALLTAVAALYVRGTAPRWPVLFAGTRACRVDLPTY
AFQRQRFWPGAPSAPAGDAVGLGLTACEHPLLGAEVALAEGAGAVFTGRLALGTQPWLRD
HAVAGAVLFPGTGFLELAFQAGLRVGCVRVADLTVQAPLVLPERDGVRVQVTVGGPDEAG
RRTVSVHAYADATASWVCHATGLLDSDPADSDAVPNEVATPTSWPPADAVPVPLHGFYER
LADDGYDYGPAFQGLRSVWRQDDDVWAEVRLPADQHAEAARHGLHPALLDAALHAWLAAG
RTAADNSGGVRLPFSWSGATLTAAGASAARVRLSPVDEDTIALTVTDTDGRAVARVDALT
LREVGQDVAAPAAGVTPASHEALFRLDWTALPAPSGTLSESDARWAVVGPGVDAAPGGHY
PDLAALTAALADGTPLPAEVLVACDAPATEQDATEQGTTERDFGAATRAALHHTLALVQN
WLADERFGAARLVLVTRGAVPADGHRAPADPVAASVWGLVRSAQSEHPDRLVLLDLAQEQ
SSSADLITSALTSGEPQLALRDGIVLVPRLAPAGTGGALLPPPGAGAWRLDVTVPGTLDS
LALVGYPEAERPLNSGEVRVAMRATGVNFRDVLVCLGMLDREVPGREGAGVVLETGPDVT
GLAPGDRVLGLFSGAYGPVAVTDHRLLARTPDDWSFTEAAAAPIVFLSAYHGLVDLAGLR
PGEAVLVHAGTGGVGMAAVQLAQHLGAEVFATASPAKWPTLRAMGLDDDHIASSRDTDFE
AKFLRVTAGRGMDVVLNSLARELIDASFRLLPRGGRFVEMGKTDLREAATVAAEHPGIVY
RAFDLRDVDPDHTAGMLAAVLDLFERRALRPLPVTTWDVRRAPEAFRYLSQARHTGKIVL
TVPDVPVDLARVPDTGLSAADVRPDGTVLITGGTGTLGALLARHLVTRHGVRHLLLVGRS
GPDAPGAAELRAELEELGATATVAACDAADRDALAQLLATIPAAHPLTAVVHAAGVLDDG
VLEAMTPERLDRVLRPKAQSAWNLHELTRDLDLSAFVLFSSVAATFGSQGQANYAAANAF
LDSLAQHRRSQGLPALSLAWGLWDTDTGMAGTLGAADVRRLGRMGLAPLPAAEGLALFDT
ALTADQALLLPTRLDLAGLDRRGTEPPSLLRALARTPLRRAATAVVSQSQSQSQSQDAAV
SFTEQLRPLSAEERERAALDLVRAHTAAVLGHSDPEAVDTERPFKSLGFDSLTAVEMRNR
LGTATGLTLRATLIFSYPTPAVLARHLLDQCAPQEARPEEALLTELDKLEAAMAALDTAD
GGASGGGASGDDGLTGKVADRLKDLLDRWTDRTADATTAGTPGTPGTTTAGTGLETATDD
EMFDLINKELGIS
>A0A0N1GPR8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MANEDKLRDYLKWVTADLAETRRQLQELESRGDEPIAIVGMSCRFPGAVRSPEDYWQLLA
DGADAISGWPTDRGWDLDGLYDPDSRRTDGSYAREGGFVHDAGDFDPAFFGISPREAVAM
DPQQRLLLETSWEAFEHAGIDPESARGGRAGVFVGCSNQEYGAGLADVPDDVRGHLLTGN
STSVVSGRVSYVLGLEGPAVTVDTACSSSLVALHLAVQALRGGECDLALAGGVTVMSTPG
VFVEFSRQRGLAVDGRCKAFAEGADGTGWSEGVGMLLVERLSDARRNGHRVLAVVRGSAV
NQDGASNGLTAPNGPSQQRVIRAALASAGLSATDVDAVEAHGTGTTLGDPIEAQALLATY
GQNRSDEQPLWLGSVKSNIGHTQAAAGVAGVIKMVLALQHGVLPRTLHVDAPSSHVDWHD
GQVRLLTEARAWERVAEDRPRRAAVSAFGVSGTNAHAVLEEAPAEETAEGSEGDLPGSVA
GEPAQVPSGVLPWLLSARTPEALPGQAARLLAHLREHPGTAPLDLAWSLANHRAALPYRA
ALLGTDHAELLAGLAAFATGDRTDAVVTVTGTVQPDGRTAFLFAGQGSQRLGMGRELYVG
YPVFAAVFDAVDAEVPFGLREIVFGDDAELLNRTEFAQPALFALEVALFRLLESWGVRPD
VLAGHSIGEIAAAHVAGVWSLADACQLVVARGRLMQALPSGGAMVAVQAAEDSLLPLLND
RVGIAAVNGPQSVVISGAADAVEEIAARFRAEGRKATALRVSHAFHSPLMEPMLAEFRAV
VSELTYAQPQLPVVSTVTGAVATAEELCSPEYWVRHVREAVRFADGVGTLAARGVTRYLE
LGPDGTLTALAQACPDAVGDGTADGNLFAALLRKDRDESVGVLTALARLHAHGATVDWRA
VLPGGRRVELPTYAFQRGRYWLADHGRPATGGGSDAGQLSGSAAELEFWNAVEHGDLGTL
AESLGLAEESLDGLVPALSTWRRRSQERSRADQWLYRAQWKPLDTASDATAPLTGRWLVL
LPEGAAQEARAEAVTAALAARGADPVVVGLPASLERAALAEQLTNLDAVSGILLDVGAVE
DAARACAAVAVALQASGDAGVAGRVWVVTRGGVSVGRSDAAVDAAHGAVWGLGRVAALEY
PDRWGGLVDLPETLDRRTVGRLAAVLGGLGDEDQVAVRASGVFGRRLARVTGGEETAGWR
PRGTVLVTGGTGVLGARVARWAAGAGAEHVVLVSRRGLEAPGAGELRDELAGLGVRVSVV
ACDVAERAAVEALLAEYPVDAVVHTAGVLDDGVIDGLSAERFAAVLRTKALSALYLDELT
RDRDLDAFVLFSSFAGSIGAAGQGNYAAANAYLDALAERRRAAGLPATSIAWGPWADGGM
ADDTGATARMRRGGVLPLDAEAATNLLARTAVSGTPAVIVADLDWADFTPAFTTTRPSPL
IGSLPEARAAVEAAMATPGHGAHDDRAGLLGRLTGLTPAEQDRVLLDAVRTCAAAVLGYP
TPDAVAAERAFRDLGVDSLTAVELRNALAALTGVSGLAATVVFDYPSPVVLARYLREQLL
GAVFEAVVPVAAVGSAGVGSDPVVIVGMACRFPGGVEDPEGLW
>A0A0N0N6Y5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MAVVAGSAVNQDGASNGLTAPNGPSQQRVIRQALAGAGLKPADVDAVEAHGTGTTLGDPI
EAQALLATYGQDRQADRPLWLGSVKSNIGHTQAAAGVAGVIKMVLALRHGLLPRTLHADE
PSSHVDWTAGAVQLLSDNTYWPRTEDHARRAGVSSFGISGTNAHVVLEEAPEDTSEEALQ
GAVAPGALASGALAPAPEAPETVRPPENTAARPTPIVPWIVSGRTAAALRAQAGRLAEFA
AGDATPGPAEVANSLVRSRSLFEHRAVVWGADRTELVRALEAVAADAEAPNATAGTARRG
ARTAFLFAGQGSQRLGMGRELYDLHPAYAAALDAVDAELPFSVREIVFGEDVERLNRTEF
AQPALFALEVALFRLLESWGVRPDVLAGHSIGEIAAAHVAGVWSLPDACQLVAARGRLMQ
ALPPGGAMVALQAMEGEVLPLLTDPDAVGIAAVNGPRAVVISGAADAVEEIAAHFRAQDR
KATALRVSHAFHSPLMEPMLDEFRAVAEQLTYGRTTLPIVSMVTGEAATADELMSPEYWV
RHVRATVRYADTVHTLADQNTGRYLELGPDGTLTALAQTTLDSSDAAVLVPVLRKARPEG
GTLLAAVARLHVDGLPVDWTTQLPAMRPVLLPTYAFQRRRYWLAATAHPGDVTAAGLERA
EHPLLAAAVRVAETGGLVFSGRLSTRTHPWLADHTVLGRTILPATAYLELAVHAGDVVGL
GHVAELTLETSLVLPERGAVQLQLALGGADEEGRRPFAVYSRAADAEPGRPWTRHAQGQL
TEEPGEAPPDTGAWPPPGAVPVVADVTGKLDWYERFAAGGFDYGPAFQGLRRVWRRDQDV
FAEVELPKDHRAEAAHYGLHPALLDAAMHTLLVDALDAAGDEQAVASLPFAWSGVSLYAT
GASALRVHLAPTGRPDEYTVSVADPDGRPVATADSLVLLRVATGQLADATEGVDADAPPP
LLVQRWRRAEPQPVAPAAETVRWALLGQGDEGLAETLDAAGVHLECYADLASLASAVDTG
VAVPGVVLTACGTTGAPAPQAIREALVAAVELIRNWVRDERFAHSRLVLVTRGALATTAG
EEVGDLASAALWGLVRSAQAEHPDRLHLLDLDATTGSGATAGATAGATAGNPVGDTAVDG
ETSRATTAAIAAAHFQAAVRDGALLLPDLDAALPEAAPAPAVPPAPDTSPTPPFAPDGTV
LLTGATGALGTLVARHLVTAHGVRHLLLASRRGLSAPGAEALVAELTAQGARVTLVRCDV
ADPGALPELLAQVPDEHPLTAVVHAAGVVDDATLVTITDAQADAVLRPKVDAAWQLHRLT
AGLDLSAFVLFSSAAGTFGAAGQAAYAAANAFLDGLAHHRRAHGLPATSIAWGLWAADSG
MTARLSAADRERMARSGMLPLTTEAGLALFDAALAVPDAAVVALARQAPDAVRPAVRRTA
ATADGGRSLAAQLKGLDAPERLAVLLGTVRAQVAAVLGHDTTDEVLPERHFAELGFDSLT
AVELRNRLAAATGCRLPATLVFDLDTPEALAADLAERLADDGELTKSGEEPERQSARPGE
SGAADTIGALFRTACQQGRIDEGFTLLQAVAELRPVFESPTELTTAATGLKLAAGDEGAA
LVCFSSYVALAGVHQYARFAAAFRGRRDVWALPTPGFGRGEPLPASLDVVARTQAEWVLR
CTDGRPYVLTGSSSGGILALAAARHLEKSGHPPLGVALLDTYMPRADSPFTRFSAEMLSG
MFDRESMFAHMDADRLSAMSWYIRMIGEWDPGTLEAPVVLVRPSEPPVSLGQDGPVEPGQ
WQSAWDGAGTVVDVPGNHFTMMESHATATAGALTDWLDTVPPPTAAGRAPAHRTEGA
>A0A0N1GWX3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MNEQEKLLSYLKKVTGDLHETRKRLREAESASREPVAIVAMSCRFPGGADSPEALWRLLG
ADGDAVTEWPTDRGWSLADHYDPEPGRPGRTYSTAGGALHGAGDFDASFFGISPREALAM
DPQQRLLLEISWEAFERAGLDPTALRGSRTGVFAGTNGQDYTGLLLASQESLEGHVGTGN
AASVVSGRISYTLGLEGPAVTVDTACSSSLVALHLAVRALRARECDLALAGGVTVLSTPG
LFLEFSRQRGLAPDGRCKAFAEAADGTGWAEGAGMLLVERLADARRLGHPVLAVVRGSAV
NQDGASNGLTAPNGPAQQRVIWQALADAQLSTADVDAVEAHGTGTTLGDPIEAQALLATY
GQDRQADRPLWLGSVKSNIGHTQAAAGVAGIMKMVLAMQHAQLPRTLHVDAPTSHVDWTA
GRVELLTEPRPWPATDGRPRAAGVSSFGVSGTNAHVILEQPAPETAAAETTTVAPTAAET
ATTEPPAAGTTTLPYVLSARSATALRAQAAALHARLRADEAPGPRDLAWSLAATRSAFEH
RAVVLTDDGDPDALPRGLESLAAGAPAAGLVQGVADVDGRTVFVFPGQGPQWPGMTVELL
DADADFRTHFTECASAVEQYVDWSAEAVLRGADGAPTLDRVDVVQPLLFVTMVSLAKLWQ
SRGVLPDAVVGHSQGEIAAACVAGGLTLDDAARVVVLRSRAITALAGRGGMASVLLPVAE
VEAQLAPWDGRISVAAVNGPASVVVSGDADAVGDLVDGLTAAGVQARRIPVDYASHSAQV
EEIREQLLTDLAPVRPRAATVPFFSTVTGDWLETERLDAAYWYDNLRRTVRFADAVQALA
AQGFRVFVESSPHPVLTAAVRDTLDAESRTGTAVTGTLRRGEGGPRRFLTSLAELGVRGA
AAVDWPAIIGAGTRVDLPTYAFQRRTYWPTPAGRDAASEAVHGADLDARFWESVESGETG
ELAAALHLDQDTLATVLPALHDYRRRSRENATVDAWRYRVTWKPLPATATPPLRGTWLVV
LPAAVHEDADHPGHALTTAVVDAVGRAGAQPVAVTVGPQDGRERIAELLRAAGDLGVTGE
VSPSGVLSLLALDEGDYAFDGADRAAAHELDRTTAHEPDRTAARESDRKVHRSDHADEPG
APDGLPRGFAATVALVQALDDLGQEAPVWFATRGAVATTAADGVDHPRQALVWGFGRVVA
LEQPQRWGGLLDLPATLDRAAAERLTAALAGLGQEDQLALRGTGLLARRFARAATGGLGA
RRAWTPTGTALVTGGTGALGRQVARRLARQGAPGILLVSRTGPDAPGTAELRAELTELGA
GHVEFAACDIADRGQLGALLDAIPAKRPLTAVFHTAAVLRDGVITTLTPGQLADVLRVKV
GGARNLDALTAGLDLDAFVLFSSTAGTIGAPGHANYAPGNALLDALAQQRRARGLPATAI
AWGPWADGGMAEGSVGERLQRHGVRPMNPELALGALQSALDHDDTTLAVTDIDWDLFAHA
YTTARPRPFLDDLPDAVRALAVRGTPHHDPQDTKGDLDGDLARQLAALPEPEQRAAFDEL
VRAHAAVVLNHTDAQDVEPTRSFRELGFDSLTAVELRNALSTAVGRPLPATLVFDYPTPT
ALAEHLRAALGPASATTPDAALPAPRATDDDPVVITALSCRFPGGANTPEEFWQLLADGT
DAISAWPTDRGWDIDALYDPEPGVPGRASTRGGGFLDHVADFDPAFFGISPREALAMDPQ
QRLLLELAWEAFERAGIDPLSLRGSRTGVFAGTNYQDYASRPLDPTTAEEVAGHLGTGNS
ASVMSGRVSYTLGLEGPAVTVDTACSSALVALHLAVQALRSGECDLALAGGVTVMSTPGL
FLDFSRQRGLASDGRCKAFSDAADGAGFAEGAGLVLVERLSDARAAGRPVLAVVAGSAVN
QDGASNGLTAPNGPSQQRVIRQAL
>A0A0N1NNV2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
NGLTAPNGPAQQRVIRQALATAGLSPHDVDAVEGHGTGTTLGDPIEAQAIQEVYGSGRPE
DRPLWLGSLKSNIGHTAAAAGVAGVIKAVQSIRHGVLPKSLHVDAPTPHVEWAGGGVRLL
DEARPWPDGDRPRRAGVSAFGVSGTNAHVIIEQAPEKEPAPGEEPAPDERASLVPAGDLA
LPWLLSARSADALRDQAARLVAFLEARPTLDPVDVAWSLLTTRAGHDHRAVVVAGGGDEV
LAGLRAVAAGGPAGTVTDGRTVFLFTGQGSQRPGMGRELHERFPAYARAFDEVAAALDVR
CAGHLAHSVREAVLSPAYGGLLDRTEYAQPAIFAVEVALLRLLESWGVRPDLVAGHSIGG
LAAAHAAGVLTLSDAAALVAARGRLMQALPAGGAMAAVAATEEEVAAALPGLPETVAVAA
VNGPRSVVVSGDEEPVLALAAGFRARGRRTARLRVGHAFHSHRMEGMLEEFRRTAKALHY
RAPALPVVSDLTGAPAGDGELGTADYWAEHARRPVRFLDVVRQARALGATRFVELGPDGV
LTAMAGDILAEEAPGPAPATVLAPLLRAGRPEAVTLLTALGRLHTDGAAVDWRAVFEGLA
PRTVELPTYAFQRRRHWLDATVTRSTTHTALLPGPVAPEPGPGWAERHGQLSGPALDTAL
LDVVRTQAAAVLGHPAAEAVAPGRAFVEAGLDSLSAVELRTRLAATTGLPLGGALTIRFP
TPRALADHLGELLRARERSDGPGAGAAEGPLTTLYLRLCAAREITAATEVIVAAARLRDA
FGPADSARHAVEPVVLARGEDPTALVCFPALTALSGPHEYARFGQALQGLRDVLAVPAPG
YAAGSALPDSADTFVAMQADAVQRLVGERPFAVLGRSLGGCVAHAVTAELERRGTPPVGL
AMVDTYPMDAAALPGMEWWMPAMVNGMVDRFDAFDLGLSDNGLTTMGSYLRTFGPWQPRP
VTTPTLLLRARAPLPGTPADPGLDTRAFWRLPHTTVDVPGDHFSVLEEHSATTAAAVEAW
LHAPRRSAPSDRP
>A0A0N1NEI4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MTDDVTGPREPTGRQVPVAIVGMAVLLPGAAGLDAYWRNLVGGVDAIGEVPEGRWDADYY
HPDSATGPATADEVYCRRGGFVDGLAEIEVTRFGIMPTSVAGTEPDQLIALKVAAEAIAD
AGGPDRLPDPHRVGVVLGRGGYLTPGLVRLDQRVRTAGQLVRTLGELMPDLTPGQLDRVR
EAFTERLGPASPESAIGLVPNLAASRVANRLDLRGPAYTVDAACASSLVAVDQAVGELAT
GRCDVMLAGGVHHCHDITLWSVFSQLRALSPSQRIRPFHRDADGILIGEGTGVVVLKRLA
DAERDGDRIYAVIRGTGVASDGRTAGLVNPDPGGQTHAVRQAWRAAGLDPAAAGSVGLLE
AHGTATPAGDAAELTTLAEVFGPADANGDGHAVIGSVKSMIGHTMPAAGVAGLVKAALAV
HHGTLLPTLHCDDPHPALTATRFRPLERATPWETTPEQPVRRAAVNAFGFGGINAHVVLE
QAPGAVAPSTAGTPAPAPAATAAVTEPERILLLAAQTPDRLAELLAADDSAVLTSGLDAG
RPHPDAGPARLGIVDPTAKRLTLARRTIAKGRAWQGRNDVWFRPGPLLDGGPDGKLAFVF
PGLEGDFTPRVDDIATHFGLPGLPGSDRSGQDDATVGDVGRHGLGVVGLGRLLDGALRRM
GLAPDAVAGHSVGEWTAMSAGGLYSGDEVNAFMGDFDPDSLTVLGLAFGALGTSAERVLA
ALEDGWGAAGLVLSHDNAPNQSMVCGPGEAVEEFIRSFRAEGVIAQVLPFQSGFHTPMLE
PYLAPIKEAADRFRLYPPTVPVWSGTTAAPFPEGDAAVRELFVRHLLEPVRFRQLVEALY
AAGHRTFVQVGTGQLGSLIDDTLGTRDHLVVAANSPHRTGLAQLRRVATALWTAGASVSP
ALPKTSGATAAPVRGAGRPPVQLDLGGALVSLDGPALTSLRAELGTVRSTVTTPNTPVPT
ASSPQPQGSDPTRLDALAGRFPVAAELSALMRDTADTVAQLLAVPRASTAVRAAAPVAVR
PPAAVPAPAVVHTAPTGPGPGSGAPVGPTGPTEPWRKVVHVSPETMPYLLDHCFYPQRPG
WPDIADRWPVVPATTIVRHIMDAAEEAAPGRLAVAVHGVRFEEWLTATPAVDVTVTAVPE
GPDRLAVSFGPRARGTVELAAAHPPSRPARWRIDPADEEPPEHTAAQLYSERWMFHGPRF
QGVTELTAMGDTHVRGVITTPAAPGALLDNVGQILGYWIMSTRTERTVVFPVGMREMCFY
GPHPEAGTDVECLIRITELTDTFLEADVQLVVGGQVWAQLTGWQDRRFDNDPKTRPVERF
PDRNTLSEHRPGGWALLHERWPDLASRELIMRNSLGGVERSQYAEHAPRGRRQWLLGRIA
VKDAVRQWLWDQGEGPVFPAEIRVHNDDAGRPYVTGVHGRALPPLEVSLAHCAESGAAIV
RPRTGGPGPGIDIEEVAERTPETLAVALAEAELRLLRTRCAADPDGGSEALWFTRFWTAK
EAVAKAEGTGFGGRPRDFTVTDASPDGSRLVVAGRRAPAYTVHCERTVNPPALPNRDYVV
AWTTGPTPEMENDR
>W9VJ65|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nitrincola nitratireducens|TrEMBL
MTRFLEEQGVVPVAVTGHSVGEVAAAWASGALPLADAVKVIYFRSAYQGKTAGAGQMTAV
ACSSEDIQQYLDEPRFNAINLAGINSAKGITLAGDIEQLTLLEAELKDKGVRLKRLDLDY
AFHSQFMDVIEEGVIEALDSIQPGQTRVPFYSTVTGAELEGSELKADYWWHNIRQPVLFK
PSIDALLEQGNSVFVEIGAHPVLSGYINEGLRTHQRKGLVISTLSRDDDRLYTLQSAYAK
LLLSGALTNFSQTFPVTGRCVDLPSYPWQRERFWHPVTSESMGLLYRHYEHPLLGYRLKH
HPMSWESELDTQRQPWLADHKVGDGVLFPGAGFVELALAAALSAQARDVLDVEELEILSP
LLLSDQHSKMVRLHLLSDSGQLRVESRERGSDEEWNTHLRGRVIAQSRGLSLAIERLHCL
RVCLILREKPTCKPPAQLVSITAQLFKRCNPVGSIRIR
>A0A447QUD8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Serratia rubidaea|TrEMBL
MKQRVIASGWGQCSPLAADVPTLIEAIAAGRCATSAPWFDNDDDWQNLRLGNNPHTARAA
RADAAPWQQLQPVIDEALTMAGLSASALQGPRVRVFLAGNGMRPNIADFAGYQDRNDAED
LLFFPAIKQLHADSYAQDALARRFVETYRLDWPPTSVYSASNSSLTALHLAQAGIAAGQT
DVALVAGWLKIVLQDVVFMGGQDMLGNGQSQPFNNQDNSVLLADGAVALVIESEEHARRR
GVTPAIAISSSVCRQSSGGRGGAFTADFRTIAQTIDGALQAAGLTPQDIACALRTPTAPS
PATRPKRWRCRRSGAETAFRWSATRGRRVMSPPAAACWILCWRRMRCCSGVCWPPPAATR
STRPWRSAYIWMRRRCRCARRTCSSPASGWTDR
>A4X3P6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)|TrEMBL
MSEAVERNYDPGDVAIIGASCRFPGARNKEQYWDNLLHGREGVTFYAKDEIEVDETLINS
PAYVRATGALDGYDEFDPAVFGVSDRMAAAMTPEHRVFLEASWEVMEDASYDPERVRGEV
GVYASTNPQSAALYSSPPDWVSAGPEVMDRSNAWLPDTITSNVLYYLGLTGEAVTVTAVC
SGFHYAVHLACQSLLLGQTDMAIAGGVMVRLPQRRGYLWEEGRILSRDGHCRPFDANGTG
SVLASGVAVVLLKPLPQAVADRDHIYATVKGTAINNNGISAMAYGLAQPERLSACIAGAM
QAGDVAPETVSMYEANGFGMPITDSLEVHAAHLAFGKQSGTCSIGAVKGNIGHAGVVAGG
SGAVKAAFALYHRSLPPTINLTELNEEIDFPRTPFVPQLEPAAWQPECGIRRAGITALGG
GGYNAHLVLEEPPRPVEREPENRRPRIVTLSALDDAAVSRQRAALSSWLAEHSDARLDDI
AYSLNLGRKALPSRWAAVISTRDELLEVLSGDGKSGRVSRFGQERRADLARFRRTEDGLA
LGSGDEMRDVQALTELAAAWVQGERVNFEVLHADERSHRISLPNYPFARRRFWRTDW
>A8L4A9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. (strain EAN1pec)|TrEMBL
MAGHEHPTWREALTGLPEAEQHRLLLDLVLRQVRRAVGDGRGPFDPRTPFVRLGLGGGST
AGFRDALGGELGLALPATLLFDHPSPARLADHLRTRVLDAPDHPIPPPIAPDPPDLPDLP
ASRAPSASAAPPDDPIVIVAMACRFPGGVRSPEDLWRLVAEGRDAVVDIPADRGWDLATH
FDPDPRRSGTFYTTQGGFLDDVAGFDAAFFGISPREALAMDPQQRLLLEVSWEAFERAGI
DPLSLRGSRTGVYTGLPVADYSPPWRTAPPVVEGHLMSGTLPSVASGRVAYTLGLEGPAM
TIDTACSSSLTAMHLAAQALRAGECTLALAGGATVMATPDVLVEFSRQQGLAPDGRCKSF
ADAADGTGWAEGAAVVLLERLSAARRHGRAALAVLRGSAVNSDGASNGLTAPNGLAQRRV
IRAALASAGVSPSDVDVVEAHGTGTRLGDPIEAQAVIAAYGQDRLADRPLWLGSLKSNVG
HTVGAAGVGGVIKMVLALRHGVLPRTLHVDEPSARVDWSAGHVRLLTEPVVWPRGNGVRR
AGVSAFGVSGTNAHVIIEDAPRAEPVPPWLDQAGLDEAGPNTGGRDQAAGDPPGGGPPAG
EELPWLLSAGSEPALREQAVRLAARVESEPRPGLADVGWSLAAGRAALAHRAAVVAGDRE
GMLRGLGALARGEPSAALIRGSARPDRQTDRLAFLFSGQGSQRPGMGRSLHGRFPVFTEA
FDAVTARLDRHLPRPLRDVVFAGPLPDAALERTEFTQPALFALEVALFRLLESWGVRPDA
LLGHSVGELAAAHVAGVFDLDDACALVAARGRLMQAMPTGGAMVSLRASEEQARELIAEL
GARAAAASGSASGAVDVAAVNGPESVVVSGDLRPVEEIAQRWRARGGTATRLRVSHAFHS
AHMDGMLEEFRGVARGVTFRAPAVPVVSNVTGAIVAPDELCSAEYWVRQVRAAVRFRDGV
DRLHERGVRTFLEIGPDAVLCGMGQDCLPAGSDAVFVPSLRRDQAEQPALARAVGRLWMA
GADVDWAAFFAGARRVDLPTYPFQHRRFWLGDHLATANAPTPGTAGEPATADGATPGRPP
AARRYRVTWTPVPTAKAAKAAGPGRWLVVIPADLTAEDSVGDCVESCVRGLEGRDAEVVR
FEVDPAAADRSSLAARLASLDPPPAARDVSGRNAPGHDVPGSDVPGCSVDVPLAGVLSLL
ALDVRELPGRQPVTRGLAGTLVLVQALGDAGVEAPLWCVTQGAVSIGGADAVTSPPQAQV
WGAGRVAALELPRRWGGLVDLPPAVDGTAADRLAAVLEGGPGEDQVAIRPSGVFGRRLVP
ARTTRTDSDSDSAGGGWRPRGTVLITGGTGALGAAVARWCADAGAARLVLTSRRGAAAPG
VPELVADLARRGAATTVAACDAADGDALAEVLAAIPADCPLTAVVHAAGVAGGFTPLQDV
DVAELAEVLAGKAAGARVLDELVGDRPLDAFVLFSSIAGTWGSGGQCGYSAGNAYLDAMA
EYRGARGLAGTALAWGPWAEGGMAVDPAIAGHLRDRGLVPMPPDEAVAVLADAVGDERCL
TVTDVDWARFAPAFTAARPSPLLGDLPEVRAVLNPPDPSTGPAGGPVAGGEAGDRGGDGP
AALLGRRATMRTAEWRRFLLDLVRAETAAVLGYDAADQIPADRAFVDLGSTSLTAVQLRA
RLAERTGLRLPTTVVFDHPTSTALAEYLAAELPGGPDGDPAPAGAAEPAFAGNHVTPAPG
PHGAAGDDPIVIVGMGCRLPGGVASPAELWRLLAEGTDAVSEFPVDRGWDVAGLYDPVPG
RVGRSYVRSGGFLAGAADFDAGFFGISPREALAMDPQQRLLLEVSWEALERAGVDPSSLR
GSDTGVFVGANIHDYATLLAAGGENTEGYFATGTANSVMSGRVAYVLGLEGAAVTVDTAC
SSSLVALHLAVRALRAGECGMALVGGVTVMSTPVGFVEFSRQRGLAADGRVKAFAEGADG
TGWGEGVGVLVVERLSVARARGHGVLAVVAGSAVNQDGASNGLTAPSGRAQERVIRAALA
DAGVGPSEVDVVEGHGTGTRLGDPIELGALLATYGQGREPGRPLWLGSVKSNIGHAQAAA
GVAGIIKIVEALRHQAVPATLHVDAPSSRVDWSTGSVEVVTEPVAWPRQAARVRRAGVSS
FGMSGTNAHVIIMEAPEPDLEATPGAGASAVAVPWLLSARSPAALRGQARRLLDHLAGSA
DRLPVPDVGWSLVRGRAALEHRAVVLGHGAGTGSDGDRPAALRALAEGESAESVVRGRVG
TSGDRVVWVFPGQGAQWVGMGAELLDALPVFAGRVAECAAALAPFVDWSLVDVLRGVPDG
SGMSGAGVVSLERVDVVQPVLWAVALGLAAVWESWGVRPDVVVGHSQGEAAAACVAGLLS
LEDGARVVASRSRVIAGGLAGGGGMVSVGLPVVEVEVRLREWAGRAWVGAGRVEVAAVNG
PSATVVAGEPAALDDLLSVWEAEGVRVRRLPVDYASHTAQVDRVRDRLTTELAGIVPRPG
DVAMWSAVTGRPVGPGALDGEYWFRNLRSRVRFDEAVRGLLAEGHRVFVEISPHPVLTAA
ITETAEVAGVPDAVVVGSLRRGDGGPDRLAAAAAQLWVRGVPVDWAPLVAGGRPAELPTY
AFQHQRYWPDAPAVRGGAPDPGVRPADHPMLGGVVPLVDTGGLLLTGLLSRGSQPWLADH
AVGGAALLPGAVFLELAVQAADQTGCDEVAELTLEAALVVPEHGGVHVQVAVGPPDGAGR
RPLAVYARPDGRSRPGDPEGPQEPWVRHARGALAVRAPGGVAADPAFDLVVWPPSGARPV
PVDDLYPRLAAAGVDYGPAFHGVRAVWRRDAELFAEVGLPEPLRGTARRFALHPVLVDAA
FQPLVLDPELGPRRLRPFSWSAVRVLADGASTLRVRLSPAGADEVAVTLADGTGQPVAEG
TLALRPASPAPAVAPPGPPPAAAAPVPVIPARRAAADADQPDASSFARRLAGLAGPDQEQ
ALLELVRAQAAAVLGHEGATAVADDRAFRDLGFDSLSGVELRDRLTAVTGLRLPAALVFN
HPTPRALAGYLRAGLEPGRAGTAAALAELDRLEAALGTAAEGDRSVLTERLQALLWRWTD
TPAAPAGGTYVPAGEDDDFESMTDDEMLEVIDRELGAL
>A0A378W8J7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium senegalense|TrEMBL
MGTADHPTETTAGFAVIGYAARFPGAPDAEAFWDVLREGRDAVSEIPQDRWDADEFFDPE
PGSPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGTAPTA
LADSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPSVAV
DTACSSSLVAIHQACQALSLGECDLALAGGANVLLTPATMITFSSAHMLAPDGRCKTFDA
AADGYVRGEGCGVIVIKRLDDAIRDGDHIRAVIRGSAINQDGASGGLTVPNGVAQQRVIS
AALKRAGVAPSEVGYLEAHGTGTSLGDPIEAQAAGAVLGAGRDAERPLLIGSAKTNIGHL
EAAAGIAGVIKVILSLENETLPKHLHFENPSPHIPWDRLAVEVVKESRPWERNGQPRIAG
VSSFGFAGTNAHVILEEAPAPTPVVAPEEVSDDQRFSLLPLSARTPAALVQLADQYRSWL
TAHPEATLADVCFTAGVGRAHLEHRAALVVNSREAAVELLGALADDRPAPGLVRGESHDV
PKTAWLFTGQGSQYPGMARELYDTEPVFAETLDRCAAAVADVLEKPLLDVIFTLDSPDAE
ETLRQTSYAQPALFAVEMGLAQLWQSWGIEPDVVLGHSVGQYSAACVAGVVSLEDGMKLM
AERGRLFGSLPAGGRMVAVFTAAERVENLTDEYPTLSVAAYNGANTVLSGPAADLEKAVA
GLAADGIRCDWLETSHAFHSALLEPILDEFEAYANQFTFQAPQRILIDNRTGAALGRSVK
MDGAYWRRHARQPVEFAKSVRTLADLNCKVLLEIGPRPVLTATALGAWPDPATAPRVIAS
LRPNTADHRQITEAVADAYVLGHLPEFGAFRRPHARKLDLPTYPFEHRQYWYRDNREEPN
QQQHVAARTQAVRLLEDGRIEELAALLGGAGDDSATLAVLTKLAAQHNQQRSTQSIADDR
YEFRWDKALTPLSGTDAADSSWILIGEESEAVKPLVDALAARGQQCRILGLPASDADEEQ
LADVLRTAATGGAALRIVHVAGLDSGAAPSMRSLLRMQHQVLAGTRRLFRAAVAADLRTP
IWLVTHGAQHVTDADIVMPEQSALWGFGRAAALELPALWGGLADLSDFTSGEWSALLNRI
TSGSDAAVKEDQIALRGQEVYVPRLVRPADLPSGKPLELRDGATYLVTGGLGSIGLEVAG
YLAAHGAKQLVLTSRRQPSEAAQKRIDALRDQHGCEIRVATADVADAHDVARLLAGVRAE
LPPLAGIVHAAGENGTTPLSELDDAEVDRVFAGKVWGAWHLSEAVAEDNLDFFISTSSIA
SVWGGFGQTAYSAANAFLDGLAWRLRRQGIAGTSVNFGPWSAGMADAESRARLEQRGIKT
LSPSDALAGLADVVANSSAHGPAHGVIARIDWSRFLPLYQQAGRRGFLAELEAALPATGA
VSPVTTSGKTKLVEQLTNAPVQQRKKLLTDYLRDSVAEVTRVDAGEIREDAGFFDLGMDS
LMAVELRRRMEQGVGKEIPVTVVMDHPRISDVADYLLGEVLGLAEQKADPAAASTAATRT
DDPIAVVAVSCRFPGAPNPEAFWDVLSGGVDAIREVPEERFDIDEFFDEDPDAPGKTYTR
YGGFLDGIDGFDPEFFGISPREAVWIEPQQRLVLETVWEGLERAGHSPEALRGSRTGVFV
GVAANEYAHLLSSEPIEKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAV
HQACQALQSGDCDMAVAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGC
GILVLKRLSDAQRDGDRICAVIPSSGVNQDGASSGLTVPNGGAQQRLIGSVLARAGLTGG
DVDYLEAHGTGTPLGDPIEVQAAAAAFGGSREADRPLLMGSVKTNIGHTESASGAAGLIK
VVLSLQHETLPQSLHFENPSPHIPWDSLPVQVVDKAMPWQPNGRPRRAGVSSFGFTGTNA
HVLVEEAPSPELTPTDEPRIDGELAEGVAPENNGATTETKQGQVEVLTLSARSPEALAAL
AQRYEAWLGDHPDVDLADLCLTAGTGRSHFEHRAALVVDSVAEARAGLADLAENRLRLGV
VRGERPYNPMTAWLFTGQGSQYAGMARELFDTEPVFAETVRRCADAVNDILPQPLLDVLL
ADNRETGGKAAETLRHTSFAQPAIFAVEMGLARLWQSWGIQPDVVLGHSVGQYAAACVAG
VFSLEDGARLMAERGRLFGSLPEGGRMVAVFADPKHVEQVAGGFPRVSVGAYNGPNTVLS
GPGDDLEKIVEKFEEEEGIRCTVAGDQPRVPLRTARSGTRRIRVLRSAVAVRETHDAAGL
QPHRHGADRPDPA
>A0A7U4DVH8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Serratia sp. AS13|TrEMBL
MPSHQLFNRGFNSFNQLLPELAVQHTDKTAFEFLRSAKEIKNQSYRQLHQRAASLASALQ
QYGHRGDRVILLYPDGEDFIGAFFGCLYAGMIAVPVPMPAKASGSAWERFIGVLRNAQTE
FIVTTGKGAETLISLSLPLAPLIFTFDQLPAVALPAGYRLQHLDSHFSGAFNPAPVSDDD
VAFLQYTSGSTGTPKGVMVTHGNLWANSQAIHRYFGHHNESRGMIWLPHFHDMGLIGGLL
QPVFGAFPCRVMSPMMLMKNPLNWLKQVSEFRATTSGGPNFAYDLCVRKISPQQAEGLDL
SNWDVAFCGAEPIRPATLRQFSEHFAPAGFRGQAFLPCYGMAETTLIVTGREKGQGMAVA
EEKSGDVVNCGEALPGTDVRIVDPDTLQPLAAGQTGEIWLRGPSIAAGYWDNPAATEATF
QACIEPDQAHWLRSGDLGFLQAGALYVTGRVKELLIVNGQNHYPTDIEETIIGADILLAD
ATVCVFAAEIAQTEQAVALLEIPERLKETLDTAALNRRLNAAVAERHGITLGEWVWVGRR
AIPRTTSGKLQRTRAREMYRQNELAVQWRSRAEQPQAAQVADVASYSVPALAALIAGIIG
TAVNGAVGEEQWDEAFTAFGLNSLQAVGVIGELEHHLGRELSPALIYDYPTINKLAAGLL
QPVARPEAASTAVASQDIAVIGIGVELPGHSGVQALWAMLQQGQSTTGEIPAHRWAGSSL
SGFNRKGSFFDRVSDFDAGYFGISPREAEYIDPQHRLLLETVQQALTDAGLQASALRGSD
TAVFIGISASDYALVSGDRVSAYSGLGNAHSIAANRISYLYDFKGPSVAIDTACSSSLVA
IDGAMQSLRSGRSSLAIAGGVNLALTPHLQKVFTEAQMLAPDGQCKTFDARADGYVRGEG
CGIVVLKPLAQALADGDRVYATLVASAINQDGRSNGITAPNGPSQQAVIARALAEAGIDS
NHIDYVEAHGTGTALGDLIEYQALEAVFAERSQSAPVQVGSVKTNIGHLEAAAGVLGVVK
TALMLHSQQRVPHLNFQQKNPHIAAISRRVAVAGNHSCAWESAAGQRYAGVSSFGFGGTN
SHVILRDCPQAAKRDETAQPLALLLVASHEEQGFNAQRDGIYNTLQMQHDVDVPAWCRLV
NTRYDHPRYRGFAYGDNRRQLAENLAQLTANKVEKPRPQVWLFPGQGTQQIGMGAALYQH
LPHYRTCFDSLAERVQERYQIDIRQALHAQDDRWQHCAKTCQLALFACSYATADSLLQFG
LRPAAVIGHSLGEYCAAVVAGQISLDQGLAMVHQRALLMDSLEQQGAMAVVFSGENEVRR
SIAPWADDIDIAAFNTPTLTTITGSSPAIDACLQAVSAQGGHARRIKTTNAFHSHLMDPI
LPAYRLWLTQHIDFAEGNIPFYSNLDALPRRHTDADYWSQQIRQPVHFLQGIQALREEGK
YTFVDLSADSSLGKFVAATDRSQPILAAADHRHEYQSLLTLLGSLWQQGHDIDWSRLYRA
TSREALTLPAIQFCRKTYWLADETPTLPPSSHEDAMSKQHQLHAEIKAIIAGYLGASPEA
LDDDLPFLEMGADSLVLLDAINTIKDRYGVVIPLRSLFEELNTLDAVIHYVVERAQVAEP
VALASESRVVTAMPQADASVIPASSPQFEQEWGIPATAPAELQGVIARQLEVMSQQLRLL
SGGHAQPLSAPALPSVPASAPVAALPAPAVASNAPATAAPAKAGAHTSWFKKETKKASLG
AERDKHIQRLTQQFVSKTPSSKHNAQQYRAVLADNRASAGFRLSTKEMLYPLVGVRSQGS
RIWDADGNEYIDFTMGFGANLLGHAPECVQQAVAAQLAQGMQIGPQSALAGEVATLIAEL
TGQHRVAFCNSGSEAVMSAVRLARAVTGKNKVALFSGSYHGVFDGILGRQQGGETPERAV
PIAAGTTASLVEDLLVLDYGSEESLALIARYADQLAAVIVEPIQSRYPDHQPRDYLHALR
KLTAERNIALMFDEVITGFRLAAGGAQAYYGVQADIATYGKIVGGGMPIGAIAGSARFMD
SIDGGFWQYGDESWPQSELIFFAGTFSKHPLTMAASKAVLDYIKSHPGLYDDINQKTHYL
AQTLNTWFVTTGTPIEIVSAGSLFRFKFSGNYDILFHHLMLRGIFIWEGRNCFVSTAHSS
QDIELFIAAVKESVNAMRVDGFFGEAGLSPDTPYPAADSQQRFMLLAAKDESGLCAGNIG
CVVETAREIDGATLAEAWALLSERHESLRMQFNGAGELQVASGVVNVDFIEERSESTDPA
ARLAEFAAKPFVLTAAPLARLLLLSQPGQTALALTAHHTVADGWSFMVMLRELLHIYDAL
AAGFSPELSAAPSYLHFMRAEKTANDAEVAQRLAAIPARRFDPASALPVVLQAAPYQGQR
LKQGLAYPNLSAQLRKVAAELRTTRFVMLNALFALTLEKFIGHSLLPVAVPNAGRDFENS
EGVVGQCVSLMPLCFNSAASASLPEFVAKVHQAILAQRDAPVLPSRCFHGEQAPLPLLAT
FNVEPSVPLAEMRQWQASLSMLPVNAVEFPLMINVVEMADELSIELDYQARYFTEQTASA
LLEQYLAAIAVLAEQGVSVVNQQFYSQVAVEV
>F6AUU6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Delftia sp. (strain Cs1-4)|TrEMBL
MRAQDAGYSGVEIAIIGMGGRFPGADSVDALWRNIREGRESVTVFSDEALRAGGTEQALL
DDAACVKSGVVLEGLDWFDAGFFGYTPREAGQIDPQQRVFLECAWQALEHAGYDAERLDV
AAGVFAGAGANLYLMRHLLGRAQWSGGIAELIALLNGNAADALCTRVAYKLNLRGPAVTV
QTACSTSLVAVHMACQSLLGMECDMALAGGVWLNLLQGAGYLHQPGAILSSDGHCRAFDA
RADGTMLGSGAGVVVLKRLDEALRDGDTVHAVIRGSAVNNDGARKIGYNAPSVDGQAEAI
RAAQAMAGVDPASVGYVEAHGTGTTLGDPIEIAALTQAFGGAGGLTGRAPGHCALGSVKT
NVGHLDAAAGVTGLIKAVMALRHRTLPPSLNFSTPNPRVDFAGSPFRVQTTAQDWPAGPL
PRRAGVSSFGMGGTNAHVVLEEAPATLPADPSESAGHTPQLLLLSARTPQALQASASQLA
RHLEQHPGMALADVAHTLRVGRKRHAHRLAVLAHGVTQAIEALDHPAPLVHFTGSVLSPQ
PGLAFLFPGQGAQHAGMARSLHAQEPVFRDIVDRCCERVRTQTGMDLRPWLLAQADDAQA
AQALARTEATQPALFIVEYAMARLWMSWGLQPEAMLGHSIGEYVAACIAGVFSLDDALDL
VVARGRIMQATEPGAMLAVGLPEAALQDWLCRGCDLAAVNAADLCVLSGRPDAIAAAEQA
LAGTGVLLRRLQVSHAFHSALLDPVLDAFAHKLASVRLNRPAIAFISNLSGRWIRDEEAQ
DPHYWLQHLRGTVRFAQGLDTLLDQSDRILLEVGPGQGLSGLARRHPKAGARTVLASQAA
ANREELQADQPARCLAQLWAAGVDAAKAPLLNSAQGARRVPLPGYPFERESHWVAATVPA
SEAAPAAPGGLHGTDPRGWLYAPVWQRSAPVVRAASVPAGGCMLLLAEAGSTLAESLAQA
WSDTQPAPVVRIEPGPLHERLGPARHALRMTERSDWTRALGQIAAEIGPVACICDLWSLG
TLDDAQAAERCLLGPLALAQALEAVSAASAVGAAGRQQMLLVTDGLEDVTGTESLQPAKA
MLHGPCLVIPQELPGMACRIVDVLPVQSGHAQGMAALAQRILAEFSEPAPACVALRGPHR
WTRRYERIAGQTAPAVTPAAPATAPRLRRGGCYLITGGLGGMGLALARHLAEHWQARLVL
LGRSALPERGQWQALAQDAQTEPALRARLQQLLELERLGAQLCLVQADVGSEAQLRTALE
QAQRAFGGMHGGIHGVIHAAGLAGDGMLADKRAHEVMQVLAPKLQGTRALLAALAGQPLD
FMLLCSSLAAVAGGLGRIDYAAANACLDALAVAHGRTAGWPLISVGWDGWRGVGMAAGTS
MPEGVGIAPEQGVHLFERILAGPVQPHVCVSTTDLETRRHADLAELLDQALPAAATTAAT
AGPVPTQVRPGGMAGFVAPEGDLETGLAALWSGFLGVAPVGAEDNLFELGGDSLMAIQLL
ARVRQAYGVEIHPAALLRTPTVRRLAELVETRLIEEIQALDAEAEPAPTTASPIYS
>A0A2T6IHS6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii TgCATBr9|TrEMBL
MLCVPLFFGCTAFFMSPIDFVRAPHSWLGGMSKFGCSFTAAPDFAYALAARKVPDDLVLE
LNFEKILACVNGAEPIRPATIEAFLQKFAPAGFQPWMMSPAYGLAEHTVGVTGRGSEGRK
PMSPKIIEVNNEKVAQGDTVELFKRSGKQENEMCTKLIVGCGIPHEDVIGYRGSCRTMRF
STQGRSYGFFYQYHR
>D0LQW1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2)|TrEMBL
MTPEDKLREYLKRSLLDLHQANEQLRAYEEKAHEPIAIVAMGCRLPGDVNCPESFWELLC
EGRDVVGDFPPDRGWCVEELYDPDPAASGKSCTRRGSFLTEADRFDPGVFGISRREALAL
DPQQRLLLETSWEALERAHVDPASLQGSATGVFVGVMYADYGARITQAPEDLEAYMGLGS
AGSVASGRLAYSFGLQGPAVTVDTACSSSLVAIHLAAQALRRGECTLALAGGVAVMATPA
AFIGFSRQRALSPDGRCKAFSADADGAGWGEGAGMLLLERLSDAKRNGHPILAVLRGSAV
NQDGKSQGLTAPNGPAQQRVILQALDNARLTPNQVDAVEAHGTGTKLGDPIEAQALLATY
GQAHTPEAPVWLGSLKSNLGHTQAAAGVAGVMKMVLALQHQMLPATLHAQTPSPHIDWSS
GTLQLVQSARPWQTNGQPRRAGVSSFGVSGTNAHLILEEAPLEQAATEQRAAATAPVAAL
PFLLSGKTEEALKAQAQRLHQHLQRHEDAALVDVSYSLATTRAHFEQRAALVASTREELL
AALAALANGESAPSLVVAPRSADGKVVFVFPGQGSQWQGMGRALLRSSDAFRAEVEACEA
AFAPYIDGSLREALEGGSSDRVDVLQPVLFTMMVSLAAHWRSLGVVAAAVVGHSQGEVAA
AYVAGALSLDDAAQIVALRSRALRRVAGRGAMAAVELGAEQLATYLAPFEEQLAIGAVNS
PRASLVAGQPAALDALLEKLAEDGVYTQKARGNHASHCRLVEPLAQELTDALQGIRPSTC
AIPLYSTVTGTRLEGHELDADYWYQNLRAPVLFQSATERLLADGHDLFVELSPHPVLSLP
LYETFDAREHSAQVVTSLRRGDGTHARMLLSLGELHNRGHKLDWHAFFAPWHPRTVPLPT
YAFQYERFWLEAPAPSDADLTSAGLSAAEHPLLGASLSLAESNTDIFTARLAVAQHAWLT
GHKVFDTVILPGTGFVELALAAAQRVGLARIEELILEAPLVLPEHEAVLVQLSVEAPDVS
GHRPLQIYARPEQAAHDAWTKHASGLLAAAERHPDDLDFHLHRWPPQGATPVALEGLYAQ
LHDAGLDYGPDFQGLRAVYKRGDDLFAEVELPESLAKDAARFVLHPALLDAALHAVVAEN
THTAADVALPFSWAQFSLRAAGAAALRVRLTRSQDTGSLSLQIADATGEPLAHVQALTAR
PVAAEQVRRAAASRGDLFKLDWAPLAAAPPRASQNTHTWALVCSEPSSFTKSLPSQVVRF
ADLASLRVSLDRGSLAPDIVLVRCHSDAASSAPAAAQAHQATAEALALLQEWLADERLHQ
TRLVFLTQGSVAAHGEETLPDLVHAPLWGLLRSAQTEHPQVALSLIDTDDHDASRSKLLE
LFDSTAEPTVECDKAQLILRDGNVLAPRLVRVTTRPDDDTRSFDPDSTVLVTGATGTLGT
LLARHLVAHHGVKHLLLVSRQGQAATGAGALIKDLESAGAEVTIAACDSADRRALETLLG
SVPPQHPLRAVIHVAGVVEDATVERLAPDRLRRVMRAKVDAALNLHELTQGLDLTTFVLF
SSFSGLLGSAGQANYAAANTFLDGLAQHRKARGLPALAIAWGFWSDRSAQTAHLGDADLQ
RFAQRGLRALSAEAGLALFDQALLRREAALSAVRLDRDVLARRRDSLPTLLRSLVPNKLA
RAASDPSAQASLPRRLRELAPEDGDRVLLDLVRSEVAAVLGISSPSSLEPQRPLQELGTD
SLMALEIRNRLSAKAGLRLPATLLFDYPTPLALAGFLRACLESGSQSHSNAVDNEAQLRQ
RIASIPLQQLRDAGLLDALLRLAGQDNGTSENNTDEAEPSRAIESMSANELIQMAFEDVD
ESSGVNG
>E3JCX3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia inefficax (strain DSM 45817 / CECT 9037 / EuI1c)|TrEMBL
MSDEKIRDLLKRVTIDLHRAQRRLRDTEAAAGEPIAIVGIGCRFPGGVRDAESLWELVAA
GGDAVGELPRDRGWDVDGLYHPDPSHTGTSYSRHGGFLYDAAGFDAAFFGMSPREAAATD
PQQRLLLEVAWETIENAGLDPADLRGSDTGVFAGITAQGYGAGASAESEGYALIGTTGSV
ASGRIAYTLGLEGPAISLDTACSSSLVAIHQASRALRAGDCRLALAGGVTVMATPSTFIE
FSRQRGLAPDGRCKSFAAAADGTGWGEGVGLLLLERLSDARRLGHRIHAVVRGSAINQDG
TSSQLTAPNGLAQQRVIRQALAAARLSPADVSALEGHGTGTTLGDPIEAQALLATYGQGR
PAEAPLWLGSVKSNLGHTQAAAGVAGIIKLVGALRHGLLPKTLHVDKPTPDVDWDAGAVR
LLTEPRPWPAGAEPRRAAVSSFGVSGTNAHLILEEAPEPEPGLPGAERPAAVPAQRTADP
AAATASGSPSPRLDDAGAAPSGPPPVAAVGAVRPPWVLTARDPDALAAVAGQLAAHVRAH
PELDVAAVAHALDRRARHARRAVVIPDPERSEPADAYLAALDGLAAGEQPAGLVLGQARE
PGRVVFVLPGQGAQWDGMTTDLLETSPRYAHHLHQAADALAPYIDWSLLDVLYQRPGAPT
LDRVDVVQPALWAITTSLAELWKAHGITPDAVLGHSQGEIAAATTAGILTLDDAARIVTR
RSQIISRLAGTGAMASIPLPANAVQAHLDAGRVTGLSIAAVNGPRTTVVSGDATAVGELV
EHYTAQGIRARVIPVDYASHSPAVEPLRTDLVAALGEITTQPTEVAFYSTVTAAVADPGT
LSADYWYRNLRQPVRFADTARALLADGHTTYLEVSPHPVLTTTLTDTLEDAATVAPTLRR
GEATLTRFHTSLADAHTHGTPVGWNPDPVPRTEPVDLPPYPFQHQPYWITPASQAARAGH
TDQFWNTVHTGDPDALATLLGSADPATHTALNAALPALTTWHRAHTTRATIDNWRYRVAW
RPVTPSPGRVPGHWLLAAPADRADAPATQALVRALVERGARVTTVRVGADVERAAVAAAI
RSALAAADASPTERVAGVLSVLGLRSDLLPDHPSVPWGLGATVGLIQALHDLGLDTPVWL
TTSGAVTTGPGDAVREPEQAMVWGLGPVLAAENPAGFGGLIDLPAEVDERAAARVADLLG
GHHGETELAIRAGAVHARRLVRAPATETDTATYTPTGTTLVTGATGAIGQHLARWLAHNG
APHLLLLSQRGPDHPDAARLTHDLAQNGTHVTLLAGDIADPHHLTHALTHIPPNAPLTAI
YHTAAILDDALTTDLTLTQINNTTRVKVDGARNLHHHTHSLTHFVLFSSMAGISGITGQG
NYAPGNAYLDALAHHRRHHHQPATSIGWTHWAKAGDGTGDSARGIAPAHVETRLARRGLT
LLPPAAALTALHHPLTHDTTHLVIADLDWNAFGRDQPGQLTAELRTAPAPRSGTASTEAA
RPGSARDAAGRLSEELATLPPARRAARLRTLVRAEASAVLGHRSTDRLEPTTSFRDLGFD
SLTAVELCNRLRTASGLALPSTLIFDYPSPDSLAEYLAKRLALDAAENAAAGGEDVLGQL
DRLEAALATASLDDATQERAAARLRELADAWGLPSGRPDQSRAEALGAQLSETSDDELID
LLGRRFGIS
>A0A3E2YH85|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MW-13|TrEMBL
MLRSDLVQPLPDLLRAHADRFGDKVAFRDDRRAVGYAALEARTRRLAGHLAAAGVGRGER
VAFCLGNRVETVETWLAVTRAAAVGVPLNPRSTDAELAHLLDDSGAVLVVIDPQHLDQLV
RLRADRPGLRVWVTGDGPAPDGVTAWRDLADAEPPVDARDDLGLDEVAWMLYTSGTTGRP
KGVLSTQRTCLWSVASCYVPIPGLTAEDRVVWPLPLFHSLSHIGCVLSVTAVGATARLID
GFSADDVLRAVDSDAATVLAGVPAMYHHLVTAARDTGFRAPALRMCLVGGAITTGALRRA
FDEVFDAPLLDAYGSTETCGSIAITRPDSPRVEGSCGRPVPGVEVRLVSPQTGVDVPVDA
EGEVWVRGPSVMLGYHGLPDVTAAALRDGWYRTGDLARRDADGNLFVTGRHQELIIRGGE
KIHPSEVEEALRSVPGVADVAVTGRPHDVLGEVPVAFVVPGPEGFDPAAGYAACRERLSY
YKVPDELYEIGQVPRTASGKVTRRRLLDRPARLRAVNGSHHDPLSTVTWRPLDLTAVPPA
APAAAADPADPAADPADPARARRWAVVGAGGESLVEPLRAASTGDRFDAYPDLAALRRDP
AVPDVTLLLTDAAPVDLADPGAVLGLADRLRERLDDDRSAGARLVLLTTGAVDASTPDRA
DDPDLVPAAAVAWAVGRCLQAAYPDRVVLVDADAAAESLALLPAAVDTGAAQVALRAGTA
RHPVLGPAPARAPARPTRVVDPAAPVLVAGADTVTGTALARHLVGAHGAGRLRLLPAGSP
DAAALAALVAELTVAGAAVTVQRPADAAPRPAHAAPDPAAAPHLADVGASGGGTGARHAA
PAAADEPVDAVFLCPSAADLADPAGAARLVALAEALDAHARHAAVTAFTVLVPAATLLGE
ADRERAAAAVGALHTLVARRRAAGLPARLVGTAADPAGPDPAASTVARTDLAAFDVAHDG
DDLVLLAHPADAAHPAWRGPAGTGPAAERDAIELRRRVAALTTVEGDRLLLDLVRAATAE
VAGLPGPGAVRPGRAFKELGFTSVGAVALRDRLARATGVRLSATAAFDHPSPDALARHLA
ARLRGATPAAASAPGGPAGGASDDPVVVVAMACRLPGGVSSPEELWDLVAQGREGLTGFP
ADRGWDLAHLFSDDPDQTGTSYVRVGGFLPDAADFDAALFAISPREALAMDPQQRLLLET
SWELFERAGIDPTSLRGSATGVFAGVMHHDYAANLRQAPPGTEGYLGVGTAGSVVTGRVA
YALGLEGPAVTVDTACSSSLVSLHLAAQALRAGDCSLAVAGGVAVMGTPQAFVEFSRQRG
LAPDGRCKAFAEGADGTGWSEGVALLLLERLSDARRNGHPVLAVLRGSAINSDGASNGLT
APSGPAQERVIRRALAVAGLTPADVDAVEAHGTGTRLGDPIEAQALLATYGAGRGEAAAL
RLGSLKSNLGHTQAAAGAAGVIKMVLAMRHGTLPATLHVDAPTSEVDWSAGAVELLTEAS
PWPAVDRPRRAGISSFGISGTNAHVIVEAPPADPEPAPGAHRAGPRAPSAAEDRRLPVPW
LLSAATGEALRDQAARLLGWLDGPGADADPADVGHALATTRAALEHRAVVLAGDPAATRS
GLTALTRADPDPAGVLTGRVVDGQLGLLFGGQGGQRPGMGRGLRAAYPVFAGAFDAACAE
LDRALTGHAPHPVAAVALAEAGGELAGLLDQTLYTQPALFAFEVALYRLLESWGVRPDAV
LGHSVGELAAAHVAGVFSLADAAALVAARARLMQQLPGGGAMVAVEADEAEVAPHLTDRV
GLAAVNGPTSVVLSGDADAVLAVAATLRAAGRRTSRLRVSHAFHSPRMEPMLDAFRAVAA
GLTYRTPHLPVVSNLTGEPVDPARLCSPDYWVAHVRGTVRFLDGMRALHRQGVSTFLEVG
PGGVLTAMAQDCLAADADELAFVPAVRTVDDEPDALLAAVARLHVRGAAVDPAALAGPGP
RRRVELPTYAFQRRHYWLPYSAVAGGPTDVGLTDAGHPLLGTVLPVAGTGQVVCTGRIAA
ATHPWLAAPADGVPLLPATALLDLLTHLGELLDLPTVARLRVPEPVPLPAELTVDVQVTV
AGPDEHLRRVARCHVRAADDQPWREVAEAVLAPADPAAGPATVVPAWPPAGARPVDLDAP
QRRALAGELARAAWVTADRLFVDVRLPEDARDSDADRYGVHPLVLDAALRLLPLADFATA
GADADAGPAARPMAVDWAGVRLHATGAHALRVCLAPAGADAVTLSAVDDSGASVLDVDRV
VLRTVPPPADGAPPPAAPAGLYAVDRLPATAPATPVPAWTLADGTPPDGPLPPVLVLRVG
DGDPGRPVPDRAHAVGLDTLAVLRRWLDDPRAETTRLALAVRDGDPVHAPVAGLVRVAQA
EHPDRFLLLSLDAGDDAAVRVALAAGPDEPEVAVRDGRALLPRLRPVEHPAAGPLPALAG
GTVLVTGGTGGVGRRVATHLATAHGVTELVLLSRAGRYADWMAALTDAGVTVRVVAADVA
DRAALAEVVAPLADRLVAVVHAAGATDDALLTGLDEARWERALRSKVHGAWHLHELTAGL
DLAAFVLFSSASAIFGSPGQGNYAAGNAFLDALAGHRRARGLPATALAWGLWAEADGMAG
RLTPADLARLARGGTRPLDTAAGLALLDAALHADRPALVPIGLDLAAVRASGEVPALLRA
LLPPPPRRAVNADPAPASAAGFADRLAGLGEPERAALLLDLVRARSATVVGHAGPEQVEP
RRPFKELGFDSLMAVELSNRLSAVTGVRLAPHAVFNHPTPELLAAHLHARLLGTAATEVA
DASTVALDEPVAIVAMACRFPGGIGSPQELWRLLDGGGDVIGDLPTDRGWPDLYDPVHGT
PGRTYVRSGGFLTGIADFDAAFFGISPREALAMDPQHRLLLETSWEALEGAGIDPGTLRG
SRTGVFAGTHGQDYADQIAPGAVADDGETIADEGHLLTGTAGSVLSGRVAYSLGLEGPAV
TVDTACSASLVALHLAAQALRQGDCDLALAGGVSVLSSPAGLTGFSRQRGLAADGRCKAF
AEDADGFGMSEGVGMLVVERLSDARRRGHPVLALVRGTAVNQDGASNGLTAPNGPSQERV
IRAALNAAGLTPADVDAVEAHGTGTALGDPIEAEAILATYGQRPADAPPLLLGSVKSNLG
HTQAAAGVAGVLKMVLAMRHGRLPRTLHAERRTSRVDWDSGSVELLTEARPWPRADRPAR
AGVSSFGISGTNAHVVVEAVPAPEPVAVPGPELPGEPGALPWLLSARTPEALAGQARRLR
DHLAERADQRPLDVAWSLASTRAVFDSRAVLVGADPDRIAAALDALADGRPAPELVRGDA
GATGRVVFVFPGQGSQWLGMGLDLLDQAPVFAERMAACDAALRPYLNWSLLDVLRQAPGA
PSLDQVDVVQPALFAMMVSLAELWRSYGVRPDAVVGHSQGEIAAACVAGVLSLPDAARVV
ALRSRAIRALAGHGTMASVALPAEVVRERTARYGDRVAVAAVNGPAAVVVSGEEAAVEEL
LAELAAEQARVRRIAVDYASHSAQVERIRAELAELLAGIAPGPAAVPLFSTTDLRWLDGE
EMGPDYWYRNLRQPVELHRAVLELAAHGHDTYVECSPHPVLTVGISETLAEHDSPTVVVG
SVQRDQGDRGRFLLSVAQLHVRGVGVDWQPALAGGRRVDLPTYAFAHRRYWPRRSADPGD
VGAAGLDAAGHPLLGASVALAEAKGHLFTGRLSAAAQPWLADHRVLDSVLVPGTGLVELC
LRAGDEVGCPVLDELVIEAPLTLPADGATQVQVTLGPADDDGRRPATLHSRPADGPADAP
WTRHASATLCADRSAGSDAAGELTEWPPPHARPVDLSGFYAGLATDGYAYGPAFQGLRAV
WTSGDEVYAEVVLPADQRADADRYGLHPALLDAALHAAHFGGLAEAGAGQLLLPFAWNGV
TLHASGAAALRVRLAQVAPYGIALTVADPTGAPVADVAALTMRPIAAGELTRADDRATRD
ALFRLDWTPLPPADDAPPVTAVALALDPDGFAVHPGPDGVAVHPGLVGFAVHPGLDALAV
AVDAGLDLPAAVLAPLGAAPGAPVPAAARHAAVHALELVRRWLTEPRWAAARLVLVTRGA
VAVHSTAELVDPAAAAAWGLVRSAQSEHPDRLVIVDVDRDGLGADQLAALLAAGEPQAAL
RGGVGYVPRLARAGSAGELTPPATPAWRLDAPVRGSLENLTLVPTDAADAVLGPRDVRVR
VRAAGLNFRDVLNALGLYPGDAGPLGGEGAGEVVEVGAEVTDLRPGDAVFGVFVGCFGPL
AVTDRRLLAPMPAGWSYVQAASVPVVFLTAYHGLVNLAGLRRGESVLVHAAAGGVGMAAV
QLARHLGAEVYATASPAKWDALRALGLDDDHLASSRTLDFEARFFAATGGRGVDVVLDSL
AREFVDASLRLLPRGGRFVEMGKTDIRDPGKVAADHPGVDYTAFDLTLENPDELQRMLVD
LLGLFERGVLAPLPTQVWDVRQAPEAFRYVSQARHVGKVVLTTPRPWDPDGTVLLTGGTG
TLGQLVARRLVETHGARRLLLVSRRGAAAPGAADELRALGADVTLVAADVADRDSLARVL
DAVPPRHPLTAVVHLAGVLDDGVVTALTPQRVDTVFAPKLDAAWHLHELTRHLDLAGFVL
FSSGAGVFGVPGQGNYAAANAFLDALALARRAAGLPGRSLAWGLWEQASEMTAKLDRADP
RITARDGQLAIPSDLGMALFDAALRAAEPVLVPTRIDVAALTERVSRPPALLRGLVRRER
RSARSATPATGGRTLADELAALAADDRPGLVVDLVREQAASVLGHGSRAAVAPNRAFSQI
GFDSLTAVELRNRLGEATGLRLPATLIFDYPDPTALAGYLLAQLAPDSGPTLPPVLTDLE
NLERSLAEATIEAELHAQIGSRLEVLMAKWRAMRTGPGDDPGLDLDIDGASDDEIFDLID
SELGL
>A0A655FSR2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MIVETVSNAIIDVVGGSCRFVLSGYSSGGVLAYALCSHLSVKHQRNPLGVALIDTYLPSQ
IANPSMNEGFSPNDTGKGLSREVIRVARMLNRLTATRLTAAATYAAIFQAWEPGRSMAPV
LNIVAKDRIATVENLREERINRWRTAAAEAAYSVAEVPGDHFGMMSTSSEAIATEIHDWI
SGLVRGPHP
>A0A125YWR9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii (strain ATCC 50611 / Me49)|TrEMBL
MMTRLPLCQQQAPPSLAGCHMLAAFQDIPERPLNRDLKELWAAYGENPFGNVLECWNRSI
PDEDAVVWLNSDGEISETTTFSELFSRITRLSSFLRAAGLQVGDRIILCYPPGTDFVTAF
FACITSGFVAVPVYPPDPSKGLSDVPRFCDINEIAGCKTALTNSLYKRVVQVITTVAKDS
RWRSVHWVCTDDVIKRHAEEAKNSVGPDFPNLSPHHPAFLQFTSGSTGNPKGVIVTHGSL
LHNCHLCWSAYQFPSHYENDGDDENITNHDFALVNQREFWRRRQEISIKSRGHRLRAFSW
LPVYHDMGLIGFVCSPILCGATLYQMSPIDFIRRPWLWLQGMSKYDCICCAAPNFAFEVV
TRKMPDNVYEHLDLSRVCGFLSGAEPIRASTIDRFCEKFGPKGVRRCAVCPAYGLAESTL
IVTARKTFQTVPKLLIVDSFQLQHEKTVVALKPEATVTMDSEEYQVLVGCGVPLEGVQVR
IVDPETKKELPPGKVGEIVVYSSSVARGYFGRPDTTKETFCYSFTDLQGKQTPPLGMRTG
DGGFMYEGELFVAARLKDLIIIRGRNFYPQDIEEAVDKVAMVRPGSSAAFAIEVDGHEAL
AVAAEVRLEEGIKGLWLRVKRQFDRSHYEQIVRDISKSVAANTGLTIHRIWLLRPRTIPK
TSSGKVRRSLTKEKLVSGKLEGILLDHAHHQHQAFYHDGPGGSRSRTRTGSGATPSGGAA
TRDGTASSNPSGDAHPKNSNTSNSITDSSHSVQRGSLRGDACVAGGRLGPSASHGGVHHE
KDHKHRGDGSGMSSPDQVPGAGAAASESSAHVALTEKVKQTVFEAAKTVLGSSEIPEIDA
PLHELGVDSIGAVEFSELISAELQVDVEPTLLFNYPTLSDVIDFFVRELEGKGSEDLAVS
LEKTGARETTTAIIGAACNLPGGTTSLNAFWDLLMCGVDAIAEVPRSRWDVEEYFDPDPG
ADGKAYVREGGFIEDAEMFDAAFFRISPSEAKSMDPQQRLLLEVAYESLYDSGYTREGLQ
RASVGVFVGCCSNDWYQVCSQLELGISSYTTTSYAPSIIANRLSYTFGLLGPSMTIDTAC
SSSLVALHIAAQELQGGSCMSAVVAGVNLMLSPHITVAFCKSRMLAPDARCKTFDASANG
YVRGEGLGSIVMKRLSQAEKDDDRILCILRGTAVNHGGRSASLTAPSGPSQQRVIRTALR
QAELTPGDIYFVETHGTGTSLGDPIEVGALKSVFGASRDAKTKPLILGAAKTNIGHLEGA
AGIAGVLKAMLALRYKHIPPNLHFKQMNPHIDVREFNVVVPTAPMAFPREDGGRLFAGVS
SFGFGGANGHVILQEALQQPSGDKPPCKRHSKRSIICFMFTGEGYEVSCMGRHLYETDDV
FKEIITKCNDILKRWLNVSLLSILYPPADKKMEMDKMMCQARFGHTALFAFEYALAESMV
SKGVKPDVVFGVGLGELVAAAFSGVMSLEEALYVVTQRAKLIDNLPPFEGVMVACRVSEQ
EVEMALSEMEINSRQSISIAAVYGRKNLILSGEQSEIDNVLMKLNIAGRWKYLPVHNVLT
MNLVSDIIPPFTHLMSTVKLCRPKVRLVSSTTGEFVDKEALSGRFWSRQVSQTVQLQQAV
GNIVASGCSLFVEIGPQVVLTKLAQQSLNGNAKDVTWVPAYDTTSDDVRVFENAVMTCNE
AIKIIGKERSLEEGQHGQEELIFHRKPFPWTEIPHPFLSGHKFTEKDDVVFENAFPRRAI
PLIADHAVNGTAMMPGAGMLEMVGAAALALDLRTTSGAVSLENISFERPMLIGAHRVTYE
YNRRHSLGEGGGAGTSPRTVRTPRLVNHAYTRLGFREKSAEKAISETAGPASTEGGRTPV
AGHHHGSYTKAGVLEDIKDYAHNVLRRAAQHAEEIDVHTPVPPSMAPPSIVARHPREGSY
GSMSRTSGIMGSNDRGDGLTVPLSVEMAIRCRVTKMKEVELSTVWDDEVTDHCFATIVIA
DKKQETYSSLQEVRCRCTERMDVNEYYDMLYDAGLQYGPRFRTIQELYRGEKEALARVHF
VGNVKQDPFESGFLIHPAVLDGALQAAGCLLEQSHSGNKVMVPVSVGSATLTKVEVFQPC
WAHVRLEETKSKAATLNVTIYDEVTREVVASLQNAVLRQVDPSASVVATIPKDLLWKVNW
QLVVEGDKEVVGRTPKVLFIGGNIELSEALENAMGSTCKTLSVDALPREKAELQKVLDAE
QWQAIVYVEAVTAGVYDALDVMNAAVRLVQAHYLNLNSGKAVGALWFVTRDTVFRDNGAD
KPGVEIPAHAGLWGLAKAARLEMEVSAGSPISMGCLDVSGADVSSMAQQILHALKSKVLT
MRETEVAVREDGLYVSRLAPQTEVDVRGAIEFHMPERGAISNLVLRPQAFASRLPPEDGQ
IELRVRAVGLNFRDVLNVMGLYPGDPGPPGADCAGVVVAVGDNVEHIEVGDCVFGVAQGC
LRTYVTTDSQLLRRMPESMTFEQAAALPVVATTVEYALHDLAKVKAGDKVLIHAVTGGVG
LVAVQLCKRVGATVYGTCSGGKKDAFAKSMGVQYVSSSRDAKAFAEDMRTFLGEDGKVDV
VLNCLIDDFIPESLKLLGPYGRFMELGKRGVWSKEKVAAERPDVQYELIAVDEMMEKDPI
WFGGMLVRVRGLVAEQKIQPLPMHVFDLADTGENGGVAAFRFMQRAQHMGKVVLKIPSPV
EEASKNGSIVITGGLGALGMVVAGWLAEEGARHICLLSRREEAPQPGEIPGWDWLRTINC
DVQFFSCDVSKYDSIRSVLRTIQTSVAPITGIIHTAGALADALLDSQTPELMKKVYNGKV
QGAWNLNRALEELGLNEQLKLCVFFSSVTSLFGNFGQANYCSANACLDALAQWRRAKGLC
CQSIQWGPWIEQGMAAELKQQVERNGMKGISNEVGLRVLHDAIRQQEKATPVIGCQAIKW
KLFMHRYIEQPPFFTNIEMDLQVTSHDSNTVLRNLPPSERRDYIKAQVAAAARQVLGSSS
PPPFDTPLQDVGVDSLGAVEFRNVLSKKLGVKLSATTLFDYPTLNAIIDHLCEVFGESSQ
KDNLSTKLGALSENDLVQEGMAIVSMSCRLPGNSTCPDLFWDMLMRCTDCVCDIPLTRWN
AEEVYSEDPDLPGKCYTRRGAFIENAEYFDNSFFGISPSEVKHMDPQQRLLLEVAYEAFA
GAGLTKEKLLGANIGVFVGACNHDWTYLIQEDKISAYTGTGSAGSVIANRVSYCLGLRGP
SVPVDTACSSSLVAADFAFEKLMLRDCTMALVTGVNLMLTPHLFIAFSKARMLSPDCKCK
TFDASADGYVRGEGAGAVLMLPYADAKAKQMTIQAVVKGTACNHVGRSASLTAPNGPSQA
EVIRMALRRAGMKPNDLKFMESHGTGTSLGDPIEVNAVRTVFAPGREKTKPLLIGAVKTN
IGHLEGSSGIAGLIKACLVLSRREIPPNLHFKTLNPHINIEDFPVQFVTDFVSLDSVEST
RKKNTAGVSSFGFGGVNAHVLLEEATRDQNATRKEENRPKICFMFTGQGSQYVGMGRHLY
EKEPVFREAITRCVEIAKEYLPLPLLSVIYPSPDERDKMQEAINETLYSQPAVFVISYAL
LELWKSRGVEPDMVMGHSLGEYIAAVCSGVISIQDGLKLVLKRAQIMSRAPSRNGVMVAC
RATAEQVEEAIHTLFGDGEKNVALASVNGLKSVIVSGNQQDVQAVLRQLGAASRAKMLRV
SHAFHSPLVKDTVAPFKRVLETVRLSKPRVMFVSTVTGKVARDELQNTNYWAEHITKVVR
FCDAVQACIAQGAKIMVEVGPRPTLSNMGKGCLPQTTADEVQWINSLEPETLSSAVFDSL
SALAKAGSGAMPAVFDRKFFPWTETCHPLLGGKNTRPDGSVVYSALLRDLVKALFLDHVV
YGKALLPATCLIEMMASATTHMISNHDEEKLVALSQVVFEKPLLVPDETSLSVLVTVETR
GQVRVASQVSNSEEEAEDHAVCQVNIVDALPAAPALTEIRARCKTEIEASQLYAQLHNVG
LQYGPRFQTIVKVFKGEDEVLGLLQAQNVTNFETGFMMHPAVLDGALQLSAVLAFEKGSS
RAMVPFGVDTVLLKSCPPDKELWARVVMNRKGVSSASATVHLYDFDGEPIAVLMGVTLRP
IEFNTAADIPRELLWEVEWESAGSYSMPQDGSLATPSGTDDSGAEDVTRTPSPLVTGENE
NTPSREVPSALPGLSTETPRASKPLSTDETSGAVLNKSVHSVLLVDYAGGHREVVASIRD
TCDVEVEVLSKPGSPELYAQQLRQFAEVVATKTETVPLSTILFLALDEATPAEQLAGGLL
ETVKVFAVEKFKKLPCIWVLTSGAQGPTRSVVSPKHAGLWGLMRTVRLELEMQIGKMVRF
GCVDLDKNLEVSVALHFILQKRTEEPFEAEMILRCPSEDSEKEPGTAEVVNRRERSASFV
SVGPEPVVPSTTDASAKSSVTSDRMALTPGALSCFDETANSTEKLIFNAFCPRLHRSPIP
VRGAVELHMPERGAISNLVLRPQAFASRTAPQSHECEIRVRAIGLNFRDVLNVMGLYPGD
PGPPGADCAGTVVAVGSGVRHLKVGDSVYGIAQGCLRTYVTTNGNLMRRMPESLTFEQSA
ALPVVAATVEYALHDLAKVKEGDKVLIHAVTGGVGLAALQFCKRVGATVYGTCSGGKKAA
YAKSLGVKYLTSSRDASAFAEDMREFLGEEEKIDVVLNSLIDNFIPESVKLLAPGGRFME
LGKRGIWTKAQMAAERPDVYYETIAVDTMMQEDTVWFGGMLDRIRDHVDSGNIPPLPLHV
FEMTDPLAGGVAAFRFMQRAQHIGKVVIRIASDLEVKIPSTTEPAATETAMLAEAGTQGN
ASIGTSTQQIADRTYLITGGMGGLGLVVAQWLVEEGARHIVLLSRRGEPSDTVKQSSIWE
YLTEKERTCVSVLPLKCDVSVKDDIVSAVKEIEARGFPPIRGIFHAAGVTADASLANQTR
EAIEQVYLPKVTGAWNLHEVCESMGLDKNLDMFVMFSSVAALLGNFGQANYSAANACLDA
LAEYRRARGLCAQSIQWGPWIEQGMAADLRQALDKVGMRGISNELGTRVLSEVVRNPRRA
TTVLCQSVIWKKFLQRYERVPPLFKNTRAGQGATADSSLMLRTMTAEERRAYVEKTVREV
VKQALGLADSPPMDLPMQELGIDSIGAVELRNALSSRLGVKMPATAMFDYPTLDAMVDYI
NSTLAEQCAGTEQDVSAETQMNLVPQIMHRLEGNIAVTSVAVHLPGSVHNAEEFWDMMHQ
MRDCITEVPLTRWNMYTFFDPDPDTLDTSYAKLGGFIEDADMFDNTCFNISPAEVRVMDP
QQRIILEVAYEAMVSAGYTSSGQASQQSIGCFIGCCNADWHMLDVPSGPFTGTGSSTSII
SNRISYTLGLRGPSLTVDTACSSSLVAMDNAMCKIIEGSCSAALVGGVNLMLSPHLFICF
SKARMLSPDCRCRTFDHRANGYARGEGAGAVFLKPLQAARKDDSTILAVVRGSAINHDGR
SASLTAPNGPAQQAVIRAALQSGGVKPADITVLESHGTGTQLGDPIEVGAIKAVFMHHRG
ADNPIYIGALKTNIGHLEGAAGIASFIKLVLCLRRRELPANLHFQQLNPHIDMTDFSAVF
PKATVDLPVTRKLFAGVSSFGFGGANAHVVIEEHFELSNAAEAPQKQTAPVKRERRSFPW
YQAFHPMLGHETKTEVDERKIDMEIRRDVFDLLAQHMVEGRPVMPAACYLETLTSAACTS
EFLHPCSRKMLRPNHHAAVTLEDIEFQRPMILEAPEGHGHQIFQILTASLGPNGNASISS
LKTGDEEQFIHATCRLSSVNDTTAFTRTPEENLKFLDEDTNRVPVDVGEMYEKLWKNGLM
LGPQFRTIHSIECSPRTAKVKLQLPQTPTSCELGFRMHPCVLDGTFQTVGPLVLAHDEQA
RKDGSSSNVGTMKLMIPFMIQRITLTSMHGVSNALWAHVALVKRESNQAIVNIDIMSMTG
EPVCCLKELTMRRLDPVPVAEIPRELTWTVDWEEGQNVDPVPANAVEVVAIDPLGMQHTV
IKELKQKGFASVQVFERDSSVEEVLRVLRISSSGDSPTSLTPASAAAGEAAKSTSLPHRV
VLFLGTGGANDAIEALDCLLQLSSGLEKAAKEDRQQEFYPIWILTKGSQSHRDKGRVSNP
VHAGLWGFARTARLEISAQTSKEASIGCVDLGPECRVADVVQHLAAIQSQEKYEREILFD
EVEEVEDQKREKGKPPSGSKRLKHFVSRLARSPLNVRGALELHMSDRGSITNLTLRPQSY
AARVTPKGDMVELRVRAVGLNFRDVLNVMNLYPGDPGPPGSDCAGTVVAVGDRVKHLKVG
DSVYGVAPGCLKTYVTTNSQIIRKMPASMSFEEAAALPVVATTVEYVLNDLAKVRAGEKV
LIHAVSGGVGIAAVQFCKRVGAVVYGTCSSEKKREFVESLGVKYVASSRDPEKFTAEMKT
FLGEEGRVDVVLNSLIDKFIPASLALLGKDGRFIELGKRGIWTHEQMRAQRPDVYYEAVA
IDVMISENPRWFGIMLDRVRTLVERKQLLSLPLTVFNMNDPNEGGVAAFRFMQKAQHVGK
VVVAIPSALDFERSTVGPPTTPQKTYVITGGMGGLGLVVAQWLVEEGARHIVLLSRRGEP
SDTVKQSSIWEYLTEKERTCVSVLPLKCDVSVKDDIVSAVKEIEARGFPPIRGIFHAAGV
TADASLANQTREAIEQVYLPKVTGAWNLHEVCESMGLDKNLDMFVMFSSVAALLGNFGQA
NYSAANACLDALAEYRRARGLCAQSIQWGPWIEQGMAADLKALAEKAGLRGISNELGIRV
LVEAVRNSKTVVTFLAQSFIWKRFVQRFDVVPPFFSNIEFETASPGAFRVLYSSMTPDEL
HTYVSNVVLDTARQVLGTSELPALDSPLQELGIDSLGAVELRNSLSQRLGVKLSATTLFD
YPTIRAIIDYIVNQVSGEASAAKATSGALVSAGLAAGRNSPIAVVGYSCRLPQGSETPDK
LWEMLRRAQDCVVEVPLTRFDVDMFYDSDIDAKGKMYVRKACFMDDADMFDNSFFNISAA
EVTYMDPQQRVMLEVAYDAFYSAAYSREHLIGKNYGVWIGCCNSDWHFLEQQSNPDKSSS
YSGPGGSGCLVSNRLSYVFGLKGPSMTIDTACSSSLVAADCGAQAMRFGYCDGALIGGVN
LMLSPQLFLAFCKARMLSPDCRCATFDEKANGYVRGEGAGAIMLRHLADAQREGKRILGI
VRGTAVNHDGRSASLTAPNGPAQQDVIRSALQIGGVDPLDVALVESHGTGTALGDPIEMG
AIKAVYGAGRSADSPLVVGALKSYIGHLEGSSGIAGILKVLLCLRHHEVPPNLHFDTPNP
HMDLSDFHVVLPKKQMKLQPAQKSSTILGSVSSFGFGGANAHVVFEEYPEPTMATDVGGE
RRSTEAAESAGKKRLAFLFTGQGSQYPNMCKQLYEEEPVFRSHMDACFTVLEGKLDVKLR
DVIYPTAENDVEMLNLLNQTGYSQPAIFCVEYALAQLMISKGFSPSVVMGHSLGEYAAAA
IAGVMDWKDALLLVHERASIMQHIDPNDGVMYACRASEQDAQAAVEKALGEKAVAVTVSA
INGPRSIVLAGTQPDVLAVLKAMDMQSRAKQLTVSHAFHCPLVGEAAALLLPKVESVKLS
NPNEGITFISTVTGKAVGAGELTKPEYWATHITKPVQFLQGMRAAVTSGEAGIFIEIGPR
PTLVNMGQQCVPRNDYTWVAPVDPKDSNRNSFPQALEKITSNMVCTYTWKRHAFPWTVVV
HPFVDKFVPDQDETKATSQKLLTPAVGELLHDHVVNGTAMMPGVGFLEAMAAGGFMMVDG
KLPSTVVALRDCEFERPMLIPKIDPSTGEFTQAAKLMITVNNKDITLKSIMDGEEEEIFH
SRCTFSLCPATSLPTEPADLLTSLQGRITTPVPITTLYETLQSVGLQYGARFQSIRECYA
AASDEVLAKLRPKLPLHSFERNFRIHPVLLDGALQTAAVLFAEMGHKRPLVPVGVKRALL
ARVPAGSEVWSHVVVKSKDLRSATMDVTLFSTKGTILGQLVDVAVRAFDAVAGAQIPKGL
LWEVSWVPKAKAPVEDGVDTVENEASETITPTAKLAVKPTGKVEGLARQPAVNGQPKWLL
LKTPSSMLEGLQKALQGTPSAFVKELDEKHPNNAISSKIHNSEWDAIIYLGALSAAASST
TCVADALLLANTLGNTAAEKPLPNVLFVTQGQHFIRECGDVPTTAVPTQTGLYGFCRSAQ
LELENIIGRPVYLGTLDFAAKDPTLDDPAAFVSALQRVLAEADPTGAAGTCEPHTVIRGG
KEMVPRLVKSSIECRGAVELHMSDRGALSMLKLRPMPKSARVPPPRDCVEIRVRAVGLNF
RDVLNVMGLYPGDPGPPGADCAGTVVAVGEGVEHLRVGDAVFGIAQGALKTFVTTSAHLV
RPLPGRLTFEQAAALPVVASTVEYALHDVAKVKKGDKVLIHAVTGGVGLAAVQFCKRVGA
EIYGTCSGGKKEEFARSVGVKYITSSRDPKKFAEDMCEFLGNGKHKIDVVLNCLIENYIP
ETLKFLAPNGRFVELGKRGIWTREQMGTVRPDVLYETVAIDTMMEEDPVWFGGMLDRIRN
LVDGSMLQPLPLHTFEMTDSSEGGVAAFRFLQRAQHIGKVVIRLSSALEVKNFTTNSRQE
TENEDSGERHTLSPATAVGKPLSQSVADQMHKTYIITGGTGGLGLVVAQWLIEEGAHNIV
LLSRRGEPPSSVKAGDPVWKYLCGEEQPNCISVATLKCDVSQKDDLLRVFKEIESRGLPP
VAGIFHAAGVTADAALASQTADSVDQVYLPKAIGAWNLHDACEALGLNKSLEVFMMFSSV
AALLGNFGQANYSAANACLDALAMYRQSLGLCGQSIQWGPWIEQGMAAQLTQHLEKVGMR
GITNELGLRVLGDVMMHPTVAVVGAQSLQWRKFLRRYAFEMPSFFSLVPMAGAGSSEASV
NLATITKEDLCELISSLAQAVSGAAEKPAVDTPLMDLGLDSLGAVEFRNSVADKVGVKLP
QNLMFENPSISSISDYILDKAAGKHGESGVTGANGGSGEGSDIPALDTPLDQWLMSVLEP
AERFALYIDSFASEYGTLQKMAAEEDIITALEDLGVEDGGDFERLHVAWDDLCNQINTAK
RMAAKDIRPSSTAVSVSDHPKPRMPHPMEDVDTLLASLDFDVSTLRPATAPDKVKNVLLT
GVTGFVGRVQLASLMQLKQRPDLRVYCLVRARNADHALSRIREATKEAKCWQETFVSRIV
PVTGDFTQPLLGLSSEEFQELARKIDIVYHTGGDVNLLSNYGRLRATNVLSVKAIIDLCT
TYKVKPLHFASTLGQFPAFFAMFTGHFSGESIREDSTPDVSQMENFYPPSRQGYPWSKWA
AERVLEGARKRGLPVAIYRLPNTYVAYKTGYTNKTDYATALMIASIQEGVFPIGAATAPL
TPVDTICDMLVEASFLEKPKHWVYHLFDPRLVTRADLEQWSQELGISYVGVKVDEFLEAI
KKRGPESPVFKFVPLMQHWRRFWFDPEERTESFPISNEHIFEDLPHMRWPSLREVFKNSL
LYSVRMGFFPKNSKSIILDPQVALNEARRICGLQLMGREGEDFFLHPWRVLQESARRECD
LLFGGQLAVYRTVRHYFMNVMYLADAQAKCPEIEKQEIQAPLIIVGLNRTGTTFLQNLMS
TDPSNRSLRYCEMIAPYGPDGNYRPKGLPNTEESWKKDPRIPFAQEILDSQLGLSEEWMA
IHTQRAELPEEDFVIFEHCGRCYSICTEFSVPSYREWLASDNYKETRKAYSFHKRFLQHL
QWQRPAKRWLLKMPFHLFTLEALFETYPDAKIIFMHRDPKETMGSWASLVKHAQQSLMDN
VDPSALGREELRAMSTMINRALAFRRSHPELGPRFLDVQYQDLVNNPIGVVKSIYKHFGI
PLTLAAQTGIASFCNENRKHRDKLTKHMYSLKDVDLTDGMVQEAFKEYYDSGLCKYLSSA
R
>A0A1N7RUR0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Paraburkholderia ribeironis|TrEMBL
MHSTGNPTHVRLDTTIVDVLCARSATDGERLAFNFMATDDAAGHELSIGMLNQQARAIAT
CLKQAGVAGRVVLLFPAGLTFHAAYYGCLYAGLTAVPIPIPQLRPGRPERTALRLSRSRE
ILRIAAPSAVLTTSSLRDKESRLNAALPELAALPWFAVDEVSIELAAAWRRPAIAAETLA
YLQFTSGSTGTPKAAMVTHGNIMAQASGHAEVFPMPADSASVVWLPHSHDWGLTDGVVMP
VINGHCCHLMAPPSFLQRPLRWLSAISRHRAYLSGGPNFAYDLCVRRIPPESLQSLDLSG
WRIAQTGAETIRPSTIDAFARHFAVAGFQRKAFAPAYGLAEAVLVATGRHDTDSRPITLS
VDRAALTKGRVEPAIAPGTSIDLASCGRPTSSLHLTIADPHSRQSVPAGRVGEIWLAGPS
LAIGYYASPQKTKDTFQAHLSTGEGPFLRTGDLGFLHDGHLYMTGRLKELIIVAGQNHYP
QEIELTVGSVHTNLRPNAAAAFSIERDGEERLVVLHEVAAGPIVPKASAIARDAVAAVAD
LHGLTLDTLVLLPPHTMPVTTSGKVERNLCRQRFLDGTLVELTRWQAPVPSRLDATGPSG
RSKDAVEIRRRLVDTIARRTGIHADLVTDEACFADFGIDSRGAVALSGELEHLLGRDLPA
TLLYDHPTLGALVEAITRTDTFRPPVAKRGRPPLTDIAVVGMACRVLGASTAEEFWNLCL
ASAGCFSEVPRERFDSSAYLQKLDDISTLQPGRIYTDKGAFLPEVDRFDAGLFGIAGREA
VAMDPQQRLLLEMAWEALENAGIAPTSLAGTPAGVYLGMSSADYQKLLMQTGTPAPWTAT
GGAPSVAAGRIAYAFGTRGPAMVVDTACSSGLVAVHLACKALRDGEAELALAGAVNLILT
PDAYQNFCQARMLSPTGRCRPFAEAADGYVRGEGGGILVLKPLDRARSDGDRILAVIRGT
AINHDGRSNGLTAPSREAQVEVVQRALADANARADEIGYIEAHGTGTALGDPIELGALGE
VFGQSARPVALGSAKALIGHLEAAAGLTGLLKAIQALHHGVIPPQLHAEAPTSLFDWTRT
TLYLPTVATSWPGRRLAGVSAFGISGTNAHVIVEAVDPSVEPVIARPPEAATRSSSVVLP
LSAADPAALAELADGYRRMLAEAPAGSAPDICFSAATTRAALPFRLAVRGRDTTELVNAL
ASARSNGSTERPIKGSAPRVIMLFPGQGAQFTGMARGLYEHCPVIRDVLDQGEALAAPHG
IPSLLSVMFGTDRQRSIDDTRWTQPAMFVLEVAVATQWRAWGVEPVLCLGHSVGELAAAC
VAGGFSLADGLALVVARSRLMHAAPGSGGMAALAADSTTVETLLGTSRGLEIAASNAPDS
TVIAGPISAVAEALRRAAALGIAGHELAVSHAFHTALMDEAVNAFASHVAEATFQPLRVP
VLTARSAELIAVDSLIAPGYWQQQLRHRVNFQAALDRAAVIEPDAWFLEAGPGVTLLSFA
AATVTGSAERCLTSFRRGADETADMLHSVGRLWQAGAPIVWGAVQRGRRVMLPSYPFQRH
RYWLGTDATPPIPATPARDAVQIKPSPKSEPLALVDPGRLSNVEPAVRQRLLRDWLRARI
ADSSLVEQVRIDDDRPLVAFGIDSLMAIRLVNQIQTELQCSVPLAQILGGGSIATLADLL
VTAIASHAGEPVSGRTLHAGSETPLPESLDPIPLSFSQLRLWLLDQLAPGNPAYNLPTSL
HLTGPLDVDALERCLVEIMHRHPVLHTSFAARNGAPILRVAPHPTMSLHRIDLAQEDNDA
ALNDIAVREAATPLDLREAPLFRATLVQMAPNDHVLLLTFHHIVTDGWSLGGILMPELAR
LYRCLVTRQPLPAAVGATYADHAARMRRTLTDAALATALAYWKQQMADAPPVATLPTDRP
RPGQRGYRGARRPWIIPASIADGVAAVGQRHGTTLFMSMLAGLKAVLYQWTGQADITIGT
TLSIRTPETEAVFGDFTNFLPLRTVLSPGQSVADLLAAVRSTTLDAFTHGHCPFDRLVAE
VNPIRCEGQNPLFAISFVLHAFDSRTQPVELSDTLSARFIPPLIQIENGTSEADLIIEAA
RGPEGLVLECEYDTDLYAAATIDRFLDHYQTWLGSLAEADEHTPVSALSTTTATAQAELV
ALGRSRQRLSASRETIAARFEAVACLIPTAVAIRDRASGRTWTYGELAQHAEALAYRLKA
RGIRLEHRVGLYLPRSGALVAAMLAVLKAGAAYLPFDTDWPLARVAAVASDARVELILHE
TGHAPDLPQRLLAVSFDAAADTGNFTAEPLPEFSPESAAYVIYTSGSTGQPKGVVVSHSN
VLRLFDTTAPNFAFGREDVWLQFHSPAFDFSVWEIWGALLHGGQLVVIPALTARDPDEIE
ALMHTEGITVFSQTPSAFRAFLRSHLPRRHSLERLRLVIFGGEALDPSMLKDWFAFYGDR
RPSLVNMYGITETTVHNTICQLKQADRAARSIIGQPLADRDLYLLDRHMQLVPIGAIGEI
YVGGGGIARGYLGRAALTAQRFLPDPFSGLAGARLYRSGDLARRLPGGELEYLGRGDQQV
KVRGHRIEPDEISKVLGDHQAVAECLVKALDEGNEKALVAYVVPTKHATSPTVERHADVV
ERWRDVFDETYALGTGAADTFNLSGWNSSYDGLPIPEHEMREWLEYSVATLRELRPRRVL
EMGCGTGMLLLRLAPDCEHYIGMDISAAALRHVDEALARRPAMHARVSLLQGAADNFDAV
APGSVDTIVLNSVVQLFPGIDYLERVIARALAVVAPGGTVFIGDVRSHALLAAFHLSVLL
HRGGQKMDDLAEQVDARCRADKELTVDPSYFHGLRTRHPGLGPVEIRLKRTRADNEMSLF
RFDVVLHRTEAGTNALACDWFAAPSGLEDLRDLLVSRTAPFGLRDIPNKRIAALAATLDL
RRHAHPSTHAPGTTIEMHPAELTHLAEQLGWRVRLQWNAADHRDGRFDALFVTGRPGDGR
GVAEAAAFGMSTVLPKDWHALANIPDHGLRYPQLASELRQHIAARLPSYMVPKAVVILDE
LPLTANGKLDAGRLPLPGRRRANEETFVAPRDALDQAIATAWTEVLGIDRISINDNFFDL
GGHSLAATQLVSRLRSTLAVDVSLRLIFLKPTIADQHASILEKLTEDARDSAGIDPVALK
LA
>A5G643|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Geotalea uraniireducens (strain Rf4)|TrEMBL
MQNIFECNLTLDNPIVKGHQIFGRSVLPGLAYIDMLSQLAKEKLKIQRDDHCFKNLAIYN
PLVVSNENPVRLRITFENVQRYWKISVESFENNATGPSKQRKLFVTVELHLNEVMPEELI
DVETVKQASTKKYDLESIYSQASKVGLVHQGMIKAKGNIYVTSTGCLVDVNTEAANNEVA
ANYMFHPALLDGAAMSSMILIRERMPGSSQEEMYLPISYESFHGKGPLLDRCYVRIDRSL
IRTVNDIATIDMDFFNPEGRLVAKLKGLTVKRVKDRDQMDPERVKVEKIERHEGVKTRDH
YEGDEANVSCVTSLERALKKVFAKYINIQMDQLENSVGFFELGLESSQLLELVKDIEQSF
QLALSPSLLFEYSNFLDLTKYLQKKLAEGGTQPQSFPSTKNVASTISSNKYKFYGSEPFL
QDHLMYGRRAIIGLAYPCLAVESYLGNSYGGYPVELNDVRVSGGPIGLKKSENVEIEVKL
NEQGAKLGFDVFKHATGESKPETVCSGFYQRNEHERLQRVDIKSIINKSKEVTSRRIGDP
GQSCLIEAEWKYNGTTSIYHIKTAGSVNTGLQRTKIADSRLLKICYLLCDTDGLGKKVSV
LEKIEKMTVFKRVADYAYVVKKVRIENPDSISYDAMVVTEGGDVVAEFINVQMQRVELPV
LLKDLISETEGYEEKNARNSSIAIVGVSGRYPGARSLDEFWGNLKAGTDSITEIPEERWD
WKQYFNEEKGKEGKIYSKWGGFISGADEFDPLFFNISPKEAESMDPQERLFLECAYHTLE
DAGYTRERLNDQTKDRLGARVGVFAAVMYEEYQLYGAQDQKVGKNTALVGSPASIANRVS
YSFNFHGPSMAVDSMCSSSLTALHLACLCIERGECDAAIAGGVNLSIHPNKYLVLSKGNF
LSSQGRCESFGKGGDGYIPGEGVGAVLLKLLCKAEEDGDQIYGIIRGSMINSGGKTSGYT
VPNPAAQGEVIREAIERAGFNARDISYIEAHGTGTSLGDPIEIAGLTRAFHQYTDETQFC
AIGSVKSNIGHCESAAGISGLTKVLLQMKHKQLVPSIHAAELNPNIEFGSTPFKVQRELT
DWNSETPRIAGISSFGAGGANAHVVIEEYVAEKKNPPTPSREHPALIVVSAKNEERLKER
VRDLVEWLATSGPGDENLPDIAYTLQVGREAMEERLGFTASTILELRGKLNNYLKDETDS
TDIYRGQAKRNKDASIRSATEEELQKAVRNWNSEKNHEKLLDTWVNGLSIDWDMIYVKEK
PGKISLPGYPFARDKYWVAGMKGTKFERSHSVSQIHPLLHENISDLAEEFRWSST
>E3FIT3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Stigmatella aurantiaca (strain DW4/3-1)|TrEMBL
MSKADVEMDNVPAGIAIVGMAGRFPGARDVDAFWRNLREGVESITRLTDAQLQAAGVSES
QRRNPRYVPARGLLEGVDLFDAGFFQYSPREAELIDPQQRLFLECAWEALENAGYEAGRF
PGPIGLFAGAGGAGYLLHHVAPQSDTRELLESLGSVLGNDKDHLTTRVAYKLNFRGPVIT
VQTACSTSLVAVQLACQALLDFQCDMALAGGVSVAFPLGTGYLPQDGHILSPDGHCRAFD
ARAQGTVPADGVGLVVLKRLEDALADGDTIRAVILGAAVNNDGASKVGYTAPSIDGQAEV
IQMAQALAGVDAGSISYIEAHGTGTALGDAIELAALKQAFRRAPREKGSCSIGSVKSNFG
HLNTAAGVASLIKTALALENRLIPPSLHFQGPDPKSGLEDSPFTVQGTATEWRAGATRRR
AGVSAFAMGGTNAHAVLEEAPPREPGSPAKPCQLLVLSARTDAALDAMKQRLHAHLSAHP
EVALADVAYTLQVGRRAFPHRFSVACRDAGAALQALQASVGASTPAVPETDRSVAFVFPD
EGLEHVKELEALARTEAVFREEVERCTRLLQSRHGLSLSGLFSGELNQADPLLAQVALFT
VGHALARWWMSLGVRPAVVLGQGPGEAVAACLAEVFTLEEALALVVARGRWMQGVPGGSR
DAAFAQEVLRLHPKPSRLALLSPGTGTGRTEPPPEHWRQPPRPPVPLTEALATLEREGHL
VLRVPSSPGRGEDALVATWSAVGQLWAAGVPIQWSALHEGQRRYRVPLPTYPFERRRHWL
GRAVEAPSLDTLEETLRRELSIPSLESHPGLAEGLRALCSSHVCAYLQASGIATHRDAVH
GRRALRERLGIQPRFHRLFDAMLAGLAEDGILQLQGEELRFLRDGGALESPAVLRQRLEA
AHPRFQGLFDFVAHCLGSYDAALPGKVEAISVLYPGGSAQFLQQCKARTAEHSHERIYLQ
LLQEALRRLAISTQGRRLRILELGGGQGLLTWPALAALRDFGVEYHFTDLGRVFVEDARQ
EAARRGLDGGMRFGVLDISRAPQEQGYEEGTFDAVIAYNVIHATRDVRQSLENAGRLLRP
GGLLGLVEAVRLARWDVLSWGLAEGWWYFDDGLRKDSPLLPLSGWEEALKPLDFEALEFF
PRAEAVREQVDHGLVLARRREARASVQALPVRPRPVPTEASASARHPRPPMAVEYLAPRT
RLEQRIAGICEELLGVEPVGVHDEFVALGGDSLIVLRLLDRLEQELGQELPTGAAFSGLT
VERLARAVEGTTPSEESSLLVPIQTAGTKPPLFFVHPAAGVAFPYFELARQLGPDQPFYG
LQAMGLDGESPPDERIEDMARHYIEAMRSIQPRGPYFIGGFSFGCLVAYEIAQQLTAAGE
PIGLLAMVDEPAPLTGHRPKPLEMARFLTTGVARSIWPHLHDYLYLVNASRKRQGKGLPK
NFKVPPRMLETFLARSALANFVPPDSRVLALRQAAILPMFQLFLIHVRETFAYEPKAYPH
RVTLFSTDEVRGSRGRKDPLMGWDKLAAGGVDVHEVPGNHLSLLKTPHVQVFARKLAECL
AQTQSFPQAKRHHPIARESHA
>A0A2K8RHA4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MSSENVRPGIEGAGTRMSNDEKVLEYLKKLTADLRQTRQRLQDVEAKSREPIAIVGMSCR
FPGGVSSPEDLWRLTESAVDAVSGFPTDRGWDLDGLYDPDLDRAGRSYAREGAFIPDAGH
FDAGLFGISPREALAMDPQQRLLLEASWEALERAGIPTDSLKGSRTGVFAGLMSSDYVSR
LPEVPDELEGYVGIGSAASVASGRVSYTLGLEGPAVTVDTACSSSLVALHLAVQALRSGE
CSLALAGGVTVMATPGTFVQFSRQRGLAADGRCKAFAAGADGTGWGEGVGMLVVERLSDA
ERNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALANARLSAVDVDAVEAHGTG
TALGDPIEAQALLATYGQDRDGDRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMRQGVLP
RTLHVDEPSPHVDWSAGAVELLLGQVVWPDVDRPRRAGVSAFGVSGTNAHVVLEQAPEVA
EGSRDEGVALPAVPWVVSGVGEAAVRAQVERLREFVVGDPGLDPVDVGWSLASARAGLSH
RAVVVGADRDELLGGLGSVVVGVSAGGGLGVLFAGQGSQRLGMGRGLYESYPVFAAAWDE
VCAQLDRYVDRSVGEVVWGDDAELIGETAYTQAGLFALEVSLYRLIASWGVRADYLLGHS
IGELAAAYVAGVWSLEDAARVVAARGRLMQALPSGGVMVAVAVSEGEVRALLTDGVLVAA
VNGPESVVLSGDEGAVQAVVDVLVGRGVRTRRLRVSHAFHSARIDGMLAEFGEVLDGVEF
HAPSVPVVSNVTGVVAGEELCSAEYWVRHVRETVRFADGLATLRGLGVGSFLELGPDGTL
TALADGDGVSVLQPGRPEPTAVMTALGGLYIRGVEVDWGAVFPGARRVDLPTYAFQRERF
WLEPSPVQPATSAVDAVFWDAVERGDAEILGVDAEQPLSAALPALASWRRARQEESVIDA
WRYRLAWTPVVGPSSQLSGLWLVVVEPDEEETDVVAALRGAGAEVRVVTVDELGAGSVAG
VVSLLSVEATVSLVRGLVAVGGDAPLWCVTRGAVCVVDGDVVDPYASAVWGLGRVIGLEH
PDRWGGLIDLPTAWDERTSDLLCSVLSGATGEDHTAIRGNEVLGCRLSRATTSGPGPSTA
WEASGTALITGGTGALGGHVARWLADTGVEEIVLTSRRGVDAPGARELVAELSATGVSTR
VVACDVADRNAVAELIGTIPDLRVVVHAAGVPSWGPLSALTAQDLQDGMRAKVAGAIHLD
ELTRDMSLDAFVLFSSVAGVWGSGSQSAYAAANAFLDGLAWRRRGVGLVATSVAWGMWGG
GGMAVGGEEFLVERGVSGMAAGLAVVALGRALCDGETALVVADVDWERFGSRFTALRPSP
LLSELIPDAADSAAPLGEFAARLQTMSEGDRMRAAVELVRVSAAAVLGHQRPEAIDPGRT
FQEIGFDSLTAVELRNRIATATGIRPPATMIFDYPTPAALAEYLSVELLGSPQDSVPPIQ
VAAPDDGDPIVIVGMSCRFPGNVESPEDLWRLIDSDGDAITAFPTDRGWDLTSLYDTAAG
EPETSYARVGGFVHGAGEFDAGFFGISPREALAMDPQQRLLLHAAWEAFERAGIPAASVR
GSRTGVFVGASPQGYGAAEASEGYFLTGSSGSVISGRVSYTLGLEGPAVTVDTACSSSLV
ALHLAVQALRSGECSLALAGGVTVMATPTAFVEFSRQRGLAADGRCKSFAAGADGTGWSE
GVGLLLVERLSDAERNGHPVLAVVSGSAVNQDGASNGLTAPNGPSQQRVIRQALANAGLS
AVDVDAVEAHGTGTALGDPIEAQALLATYGQGRDVDRPLWLGSVKSNIGHTQAAAGVAGV
IKMVMAMRHGVLPRTLHVDEPSPHVDWSSGAVELLRERAAWPEMNRPRRAGVSSFGVSGT
NAHVVLEQAPGAVEGSRGEGVALPAVPWVVSGVGEVAVRAQVERLREFVDRNADLDPVDV
GWSLVAARSVLSHRAVVVGADRDELLGGLGSVVVGVPVVGGVGVLFAGQGSQRLGMGRGL
YEAYPVFAAAWDEVCAQLDRYVDRSVGEVVWGDDAELIGETAYTQAGLFALEVSLFALVS
SWGVRADYLLGHSIGELAAAYVAGVWSLEDAARVVAARGRLMQGLPSGGVMVAVAASEGE
VLPLLADGVAVAAVNGPESVVISGEEGAVQAVVDVLDGRGVRTRRLRVSHAFHSARMDGM
LAEFGEVLSGVEFHAPSLPVVSNVTGEVAGEELRAPEYWVRHVRETVRFADGLATLRELG
VGSFLELGPDGTLTALADGDGVPVLRRDRPEPVSVMAALGGLCVRGVEVDWGGVFPGARR
VDLPTYAFQRERFWLEPAAGEPTTSAVDAAFWAAVERGDVGSFGIDTEQPLSTALPALSS
WRRRHQERSLVESWRYRLDWSPIGAVSELPTLRGTWLVVGDTGDEVAAVLRAAGADARAV
TTAELGEVAAAGVVSLLPVEATVSLVQALGTAGIDAPLWCVTRGAVSVVDGDVVDPVQSG
VWGLGRVIGLEYPDRWGGLVDLPGVVDEEAGVWLCRVLGGGMGEDQVAVRGGGAWGARLV
RVVGSGLGGSVVWRGGGSALVTGGTGALGGHVARWLAGAGVENIVLVSRRGLAAPGVLGL
VAELEGLGAVVRVVGCDVGVRDQVVGLLEGIVDLRVVVHAAGVLDDGVLESLSAGRVGEV
WRVKVDGALHLDELTRGRDLDAFVLFSSAAGTVGSAGQGSYAAANAALDGLAWRRRAEGL
VATSVAWGAWADSGMGAGHTRTMAPRLALAALQRALDDDETALMIADIDWEQFGSRFGAV
RPSPLVGELLGGAAHSAPAVGEFADRLRSLPPAERERTVLELVRGQVAVVLGHATPAAID
TAATFQSAGFDSLTAVELRNRLMAATGVQAPASVVFDYPTPELLAGHLREQLLGAGSAAF
STTVATTPVADDPIAIIGMSCRFPGGVDSPEELWRLLESGTDAISAFPQDRGWDLVGGAD
DASVRAGGFLYTAAEFDPAFFGISPREAIAMDPQQRLLLEASWEVFERAGIAADALRGSP
TAVFVGTNGQDYAALVGNAPQRADGHLATGSAASVASGRLSYTFGLEGPAITVDTACSSS
LVAMHLAAQALRSGECRMALAGGATVMATPTAFAEFSRQGALAADGRCKAFAAGADGTGW
GEGVGILLLERLSDAERNGHRVLAVMRGSAVNQDGASNGLTAPNGPSQQRVIRQALANAG
LAARDIDAVEAHGTGTTLGDPIEAQALLATYGQDRDADRPLWLGSIKSNIGHTQAAAGVA
GVIKMVMAMGHGVLPQSLHIDEPTPHVDWAAGRIALLAEASPWPETGAPRRAGVSSFGVS
GTNAHVILEQASAVAEVEETETARTPEPSAVPWVLSAGSEAGLRAHALRLRSFVSADVDL
RPVDVGWSLASTRAVLSHCAVVVGGDRDELVRELEAVAGGSGTIGEARTHSGVVFVFPGQ
GSQWVGMALELVESSSVFAGRLGECAEALGPFVEWSLWDVLGDEVALGRVDVVQPVLWAV
MVSLAELWRSFGVVPSVVVGHSQGEIAAACVAGALSLEDGARVVALRSRALLALSGRGGM
VSVPVSVDRLRGRAGLSVAAVNGPVSTVVSGPVGVLDAVLEEFPEAKRIPVDYASHSVQV
EEIREGLADALASVRPRTGEVPFYSTVTGRLVDTVGLDGEYWYRNLRETVEFRSAVEGLL
ELGHTVFVEASPHPVLTVGIQDTADATDITHTDILVTGSLRRDDGGPARFLTALAELFVR
GVATDWRQAFEGIGARHIDLPTYPFQRERFWVEPIAPGVVRDTDATTADGDFWAAVERED
TASLAATLQVDGASLGDLLPALSAWRRRRHERSALEAIRYQVNWKPLVDDRPVTLSGVWL
VVASQADADHEWVSGVTEMLAEHGAEPVVCLVDERHLDRVVLADRLTSMTDASSGTSTSG
PSGANGTTSAASISGVVSLVALDQRPHPDFASVPIGFAMTVLLTQALDDACVEAPLWSLT
QSAVSTGPADILLTPAPAQALVWGVGRVIALEQPRRWGGLIDLPTQANTRSRARLARVLS
SVSGEDQVAIRAVGAFGRRLAHAPALRTDLPSWQPRGTVLVTGGTGALGGHIARWLAHQG
AEHLVLTSRRGMAAPGASELVADLEAAGAAVTVAVCDVAERAQLAELVAEVGPLTAVVHT
AALLDDATVDSLTTEQLHRALRVKVDGAMHLHELTRDMELSAFVLFSSLSGTVGTPGQGN
YAPGNAFLDALAEHRKAEGLVATSVAWGLWAGGGMGAGEAGEVARRHGVPALSPELALVA
LRTAVEQGDAVVTVADIAWERHYAAFTATRPSPLLADLPEVRRLIEAGAAAVVEETDLDR
SGLRGRLAGLDEAEQRRLLLDLVRRNVAMVLGHTDPEAVPSHRVFQELGFDSVTAVEFRN
RLGAATGLRLPATAVFDYPTPLALAEYARSELLGTAGEPLRAEPSGSLVDDEPIVIVGMS
CRFPGGVSSPEDLWNFLAEGGDAMSAFPGDRGWDLAGLFHSDPGHPGTSYTRTGGFVHDA
TEFDADFFGISPREAVAMDPQQRLLLEASWEAFERAGIDPRSLRGSETGVFAGTNGQDYV
SLLGGDQPQEFEGHVGTGNSASVMSGRIAYVLGLEGPALTVDTACSSSLVALHLAVQALR
SGECSLALAGGVTVMATPGLFVEFSRQRGLAADGRCKAFAGAADGTGFSEGVGMLAVERL
SDAERNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALANARLSAVDVDAVEAH
GTGTALGDPIEAQALLATYGQGRDADRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMRQG
VLPRTLHVDEPSPHVDWSAGAVELLLGRVVWPDVDRPRRAGVSAFGVSGTNAHVVLEQAP
EVVEGSRDEGVALPAVPWVVSGVGEVAVRAQVERLREFVDRNADLDPVDVGWSLAATRAG
LSHRAVVVGADRDELLGGLGSVVVGVSAGGGLGVLFAGQGSQRLGMGRGLYEAYPVFAVA
WDEVCAQLDRYLDRSVGEVVWGEDGGLIGETVYTQAGLFALEVALFALVSSWGVRADYLL
GHSIGELAAAYVAGVWSLEDAAKVVAARGRLMQGLPPGGAMVAVAASEDEVQGLLADGVS
VAAVNGPESVVISGDEDAVQAVVDVLVGRGVRARRLRVSHAFHSARMDGMLAEFGEVLDG
VEFHAPSVPVVSNVTGVVAGEELCSPEYWVRHVRETVRFADGLATLRELGVGSFLELGPD
GTLTALADGDGVPVLRRDRPEPVSAMAALGGLYVRGVEVDWGGVFPGARRVDLPTYAFQR
ERFWLESSPVQPTTSAVDAAFWDVVERGDAQALGVDVEQPLSAALPALASWRRARQEESV
IDGWRYRLGWTPIPAVSGELGLTGTWLVVVEPGADGTDVADALRSAGAEVRVVTVDELGA
GSVAGVVSLLSVEATVSLVRGLVAVGGDAPLWCVTRGAVCVVDGDVVDPYASAVWGLGRV
IGLEHPDRWGGLIDLPMEADAPVDALLAGVLAGHTGEDQVAIRATGAWGARLTRATPGAD
TFAAWRGRGAALITGGTGALGGHVARWLSGTGVEHIVLTSRRGMATPGATELVTELEELG
VQVTVAACDVADRDAVATLLATIPDLRVVVHAAGVPSWGALDSLTPDEFEESVRSKVAGA
ANLDALLADAELDAFVLFSSVAGVWGSGSQSAYAAANAFLDGLAWRRRGVGLVATSVAWG
MWGGGGMAVGGEEFLVERGVSGMAAGLAVVALGRALCDGETALVVADVDWERFGARFTAL
RPSPLLSELIPDTSEPLTPTVGAFAVELRGLSREDRDRTVTELVRAHAAEVLGHQSPTAI
GLDRTFQELGFDSLTAVELRDRLSTATQLRFPASVIFDYPTPAALAEHVCGAALGLAEEI
QIPQTPNAVDDDPIVIVGMSCRFPGGVDSPEALWRLVSVGDDAVSPFPSDRGWDLAGVYD
ADATRSGRSYVRSGGFLHDAAEFDAGFFGISPREATAMDPQQRLLLETAWEAFERAGIPA
STLKGSQTGVFVGASTQGYGRGDGQAPEGSEGYLLTGNASSVVSGRVAYTFGLEGPAVTV
DTACSSSLVALHWAVRALRSGECSLALAGGVTVMATPATFVEFSRQRGLAADGRCKSFAA
GADGTGWSEGAGMLLVERLSDAERNGHPVLAVVSGSAVNQDGASNGLTAPNGPSQQRVIR
QALASAGLAAQDVDAVEAHGTGTRLGDPIEAQALLATYGQGRDADRPLWLGSVKSNIGHT
QAAAGVAGVIKMVMAMRHGVLPPSLHIDEPTPHVDWSAGAVELLTGRVVWPDVDRRRRAG
VSAFGVSGTNAHVIVEQAPEVAEEPQVERGELPAVPWVVSGSGEAAVRAQVERLRAFTDR
NPDLHPVDVGWSLAATRSVLSHRAVVVGADRDELLGGLGSVVVGVSAGGGLGVLFAGQGS
QRLGMGRGLYEAYPVFAVAWDEVCAQLDRYMDRSVGEVVWGDDAELIGETAYTQAGLFAL
EVSLYRLIASWGVKPDYLLGHSIGELAAAYVAGVWSLEDAAKVVAARGRLMQALPPGGAM
VAVAASEGVVRGLLADGVSVAAVNGPESVVISGDEDAVYAVEEMFITGGVRTRRLRVSHA
FHSARMDGMLAEFGEVLNGVEFHAPSLPVVSNVTGVVAGEELCSPEYWVRHVRETVRFAD
GLDTLRELGVGSFLELGPDGTLAALTDGDGLPVLRRDRPEPLSVMAALGGLYVRGVEVDW
GAVFPGGRRVDLPTYAFQRQRFWLESASAQPETSAVDAAFWDVVERGDVRALGIDGEQPL
SAALPALASWRRARQERSAIDGWCYRLDWTPVPAVSGEPGLTGTWLVVVEPGADGTDVAA
ALRSAGADAEVVTSVELGAGPVAGVVSSLSVEATVSLLQALVAAEVDAPLWCVTRGAVSV
VDGDLVDPDQAGIWGLGRVIGLEHPDRWGGLIDLPAELDDRDGEALVGILAGDTGEDQIA
IRANGTWGARLTRATPTGEVRTGGVMAGGAMPTGGLMAGEVARTGEAAADGATPIGGADE
ASTAWRGRGTALVTGGTGALGRQVARWLVDSGVERIVLTSRRGAEAPGAAELVAELGSRV
RVVACDVADREALAALLATIPDLRTVVHAAGVLDDGVLESLTPERIRAVMRAKADGARHL
HELTNGTDLDAFVLFSSAAGTVGNAGQGSYAAANAVLDGLAQRRRAEGLVATSVAWGAWA
QSGMAAGVARSQGMDARSALAALGLVLAADETMVMVADIDWATFGARFTAARPSPLLSEL
LGDGSGPTEPTGGEPADAFATRLEAMADRERAATVLDLVRSHVAAVLGHTASEAIDPARP
FQEIGFDSLTAVELRNRLTAATGVRLPASAIYDYPTPEALAEHVCREALGVGGRIPAPAA
PRPVDDEPIAIIGMSCRFPGGVSSPEDLWGLLAEGRDAVSEFPADRGWNLAELYDPDPDR
PGSSYVRAGGFLDDAAAFDPGFFGISPREALAMDPQQRLLLEVAWEAFERAHMSPATLKG
SRTGVFVGTNGQDYAALASGAPQSAEGYLGTGSAASVASGRLAYTFGLEGPAVTVDTACS
SSLVALHLAAQALRSGECSLALAGGATVMATPAAFLEFSRQRALAADGRCKAFAAAADGT
GWGEGVGMLLVERLSDAERNGHRVLAVMRGSAVNQDGASNGLTAPNGPSQQRVIRQALAN
ARLSATDIDVVEAHGTGTSLGDPIEAQALLATYGQERPEEKPLWLGSVKSNIGHTQAAAG
VAGVIKMVMAMRHGVLPRTLHVDEPSPHVDWTVGQVELLVEAREWPRNGAPRRAGVSSFG
VSGTNAHVIVEQGPEVARPDQVRGLEPVSASVPVPVPETLPVAESEPEPGSELESLPAPG
LEPSPLPESARERSMPVPWVLSGAGEAGLRAQVERLASFIDAHPGLDPADVGWTLVASRS
LQAHRAVVVGTDLAELRRGLDTVSTGGVAQPGRKVVFVFPGQGSQWAGMALELLESSPVF
ARRMRECADALAPFVEWSLFDVLGDEAALGRVDVVQPVLWAVMVSLAELWRSYGVVPSAV
VGHSQGEIAAACVAGGLSLEDGARVVALRSKALLALSGRGGMVSVPVPADRLRNRPGLSV
AAVNGPASTVVSGAAEVLDAVLAEFPEAKRIPVDYASHSPQVAEIQRELADALAPVQPRG
GQVGFHSTVTGRLIDTSELDPDYWYRNLRHTVEFQSTVEALISQGHTVFVEVSPHPVLTV
GIQDTVDTVDTVDTAVTADTTPIADATDATDATDGTGGADATGAVGADIVVTGSLRRDDG
GPVRFLTALADLHTRGVDVDWRPVFTRTRTVDLPTYAFQRERFWLKPARAVTQASGLGLG
DIEHPLLGAVLPLPGAEGGVLTGLLSLDGQPWLADHMVRGTVVFPGTGFVELALQAGQHF
GHPVVEELTLQAPLVVPGQGGVQIQVAVSTADERGRRPVTVHSCRAGEWVLHASGTLGAM
GDLDVTETHPTEVARSLEVWPPEGARRVDVSGMYETMAERGYGYGPAFQGLRAAWTRDDA
IYAEVALEPEAQDVAARCGAHPALLDAALHGVGLGRFLADPGQAYLPFSWNGVVLHAVGA
SAIRVVLSPAGPDAVSLEVADPTGAPVLSVASLALRPLSGRRIADTRGVDQDSLFRVDWA
ETPLPIATAGSAPDEFDVSAKSDSPVKFDAPVEYDALAPDAPVPHIVALTCESAGDAVSA
VVCRVLAAVRRWLADERCARSRLAVLTRGAVATAPGESVDDLGAAAVWGLLRSAQAEHPD
RFVLIDHDGHQDSRTALAAALTAAAAGGHAHLALRRGRALTPQLAPLTPSVTAPSVTIPS
VTAPSGATPPVTNPSAATPALEDGVPWRMDVTSQGTLENLAAVPCPEAAGALGAGQVRVA
MHAAGVNFRDVVVALGMIPGQDVIGSEGAGVVLDIGPGVSDLAPGDRVMGLFSGAFGPVA
LTDHRLLARLPEGWSFADAAATPVVFLTAMYGLMDLAGLRPGESVLVHSAAGGVGMAATQ
VAHWLGAEVYATASPGKWDTLRAGGVADDRIASSRSLEFADRFGRVDVVLNSLAGEYVDA
SLGLLADGGRFLEMGKTDIRDGDRVAAVHGVRYQAFDLMDAGPDRVGELLRLLVSLFERG
TFTALPTRAWDVRRAGDALRFLSQARHIGKLVLSIPRPLREGDTVLITGGTGTLGGLVAR
HLVERHGVRDVVLAGRRGPDAPGAAELAGALREHGAQVRVVACDVADRDELARLLDTVPR
LRMVVHTAGVLDDGVIESLTPERVREVLRPKVDAAWHLHELTADRELAEFVVFSSAAGVL
GSPGQGAYAAANAWLDALMARRRAAGLPGLSVAWGLWAERSGMTGHLSDRDLARMARAGA
TPLATEQGLRLLDSARAATEAVVLATPLDAAALRAQADAGALPALFRGLVRAPIRRATGA
GPVEDESSLRGRMAAMPVAERQQLVLDLVRTQVATVLGHGTPAAVDTARTFAEAGFDSLT
AVELRNRLRTATGVRLPATAIFDYPTPAVLAGHLLRELDGTADMAVARSAAPAAATDRDP
IVIVGMACRYPGGVTSPEELWELLDTGRDAVSDLPDDRGWDLDGLYSADPDGSGTSYVRA
GGFVHDAGEFDADFFGISPREALAMDPQQRLLLEVAWETVERAGIPVASLKGSQTGVFVG
AASQGYGTGAGQAAEGSEGYFLTGGAGSVVSGRLSYTFGLEGPAVTVDTACSSSLVALHL
AAQALRSGECSLALAGGVTVMATPGIFVEFSRQRGLAADGRCKAFADAADGTGWGEGVGM
LLLERLSDARRNDHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVVRAALANAGLAASEV
DAVEAHGTGTSLGDPIEAQALLATYGQERERPLLLGSIKSNIGHTQSAAGVAGVIKMVLA
MRHGTLPRTLHVDEPSTHVDWSAGAVELLTRPAEWPGTSRPRRAGVSSFGVSGTNAHVIL
EQSPTESGTDTESGTDPRQAPERAPAVVPWVLSGRGERGLRAQAERLRYFLAAHPESGLA
DVGWSLAATRSALSHRAAVVGADRAELLDGLAALAAGEPAPGVVLGTAGPGRVGVLFAGQ
GTQRAGMGRELYQAFPVFAAAWDEVCAALDPHLDRPLGEVVTDTTGVLDTTGALDATGAL
DATAYAQAGLFALEVSLFRLVSSWGVRPDYLLGHSIGELAAAYVAGVWSLEDAAKVVAAR
GRLMGALPPGGAMVALAAPEDQVRPFLTDRIALAAVNGPSSVVVSGDEDAVRGVAEAFAA
RGVKTRRLRVSHAFHSPQMDGMLIAFGEVLGTVDFRTPRIPVVSNLSGAVAGEELCSPAY
WVRQVRETVRFAAGLERLRELGTDTFLELGPDGTLTALAQAQVTGADAEFIPTLRADRPE
PVTVTTALAQLYTHGVEPDWSAAFPGARRTELPTYAFQRSRFWLEPSRTPGDAAGFGLGA
LDHPLVGARVPLPDADGVLLTGRVSADAHPWLTDRRVLGVPLFPATGFLELVLQAGLQYD
CRTVDELTIHEPLVLPERGAVEVQVSVRGADESGRRPVTVYCRRDQRWVRYATAVLGADR
PPAPEHPETWPPTGARPLESGATPAWRRGDEVFLDIELPEVAGAGAGRWTLHPALLDQAL
RGEALAGLVTAPEGAHLPFSWTGITLHTTGATRLRVTLAPVGPDTVSLQVADAAGTPVLS
VDSLVLRPVSGQRLRQANAALFRPVWAASRTRPEPDTGTVRWALVGDPDAWKDAWEDVWE
DAWEPDTFGAPVAVYPDLSAIEDVPDIVLLPCVSEGGTASEVAVRVSEAVRTWLAGERFA
TSRLVLVTRGALATAAGEDVEDLAAAAVWSLVEPIQAAEAGRLTLVDTDTGDLRTLRAAV
AVEEGRVALRAGAVLVPDLATAVATEQDPPAWGPGTVLVTGGSAAAVARHLIAEHGVRDL
VLAGDGDMAGDGDVAGDGDVAELAALGATVRLAPCDPADDQALAELLAEIPGLRSVVHTA
ADAPERTRAGALSPETLRPQLRSGVAAAWNLHLATRGLELERFVLFTSGAGTLGSAYADA
LAAHRRALGLPAVSVSTDLGLALFDEACAGPGEAVRVTTAMPVPARTEAVRQPVEQAPAA
EASATTLLERLAGRTEDEQDEILLELVRGQVAMVLGHPDATMVDPDRGFVDMGFDSVAAV
KLRNQLAGATRLDLPASLTFDHPTAVDLARHLRAEMLPDDAAAAILVLEELNKLDDSILV
LDPGSAARVRISTLLQDLAAKWVERADRP
>A0A2K8RJF1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MRTDPSAQFIEALRESVKQNEQLRARNRELSAAWHEPVAVIGMACRYPGGITTPEQLWQA
VLDGRDVMSAFPDDRGWDLSALYDPDPDAPGTSYVRTGGFLDGMAEFDADFFGISPREAM
AMDPQQRLLLETSWEVFERAGIRADTMRGRRVGVFVGANGQDYGLVVHGAAGLDGHTAGG
VSASVLSGRVAYALGLTGPALTVDTACSSSLVGLHLAVQSLRQGDCSLALVGGVAVMATP
GAFVEFSRQRGLARDGRCKAFAAAADGTGWSEGVGMLLVERLSDARRNGHQVLAVVRGSA
VNQDGASNGLTAPNGPAQERVIRQALDAAGLRPEEIDLVEAHGTGTALGDPIEARALLAT
YGQDRERPVWLGSLKSNIGHTQAAAGVGSVIKTVMAIRNGLMPRTLHVDAPTPHVDWSGG
EVRLLTEAQPWQEGPRRAGVSSFGMSGTNAHVVLEAAPEPAPDPGAVPEPASELGAARGP
EPTVLPWTLSARGGAALAEQARRLAASTVGLDPRDVGFSLATTRAELEHRAVVLGATGTE
LRDALTALAQGDTSPRLVVGAEAAAPRRTVFVFPGQGSQWVGMAVELLDSSPVFAARFAE
CERALSPFVDWSLADVVRAGDFGRVDVVQPVLWAVMVSLAALWESVGVRPDAVVGHSQGE
IAAAVVAGALSLEDGARVVALRSKAIAGLAGRGGMVSVPLPVDEVRSLLPEGVSVAAVNG
PSSVVVSGDVAGLEQVLGVVERARRIPVDYASHSARVEEIREALVGALGGVVPTAGHVSF
YSVTLGAWHDGSGLDAGYWYRNLRETVEFDSAVRELIGHGFDTFVEVGPHPVLTVDIDAT
AEAAGSDTGVIGTLRRHDGGLDRFLHSAAEAYVRGVEVDWGRCLEGGRRLDLPTYAFQRR
RYWPRPALGRAADATGLGMDVTGHPLAAAFLDLGEEGCVLTGLLSPRSQPWLADHVIADS
VLLSGTAVLELAAHAGRLAGCPRVAELTLTTPCKLPPTGGLAVRVRVGPDEDGTRTVAVS
TRTDDGHWSRNAEGSLSTLPAPAPAAPAPAWPPPGASPVGLEGFYDRLTDAGYGYGPAFR
GLRAAWRRGDDVFAEVELPETEQPAGFDVHPALLDAGLHALAADAQGVSVPYSWRDVVLE
PGTSRALRVHLTRSGADAVTLRAFDIVSGAPVASVGSLVTRPSATSPDRLHRMSWTPVPL
PDRRARCAVVGPDPFGLADADVEPLPGLDALDTVPDAVLVSCAADATDPVRGAYTLTARA
LDLVRSWLADDRYADARLVVVTRNAVAATGEDVPDPAGAAVWGLLRAAQAEHPGRLAVVD
VDGVAESAGLVAAAAATEEPQIAVRAGAMFAPRLTRDSAELTPPDGAWRLSAAEPGTVDG
LRLEPAPEALAPLKSGEVRIAVRAAGLNFRDVLIALGTYPGAAGIGNEGSGVIVETGPDV
PGLAVGDRVFGLIADAFGPTAVIDHRLVRRTPVAWSFAEAAAVPTAFLTAYYGLVDLGRL
RPGQSVLIHSAAGGVGMAAVQIARYLGAEVYATAAPAKQHVLRGAGIEEARIASSRTLDF
RERFRAATGGRGVDIVLNSLAGAFTDASLDLLADGGRFLEMGKADVRTGLPVGSYQAYEL
MEAGPDRIRAMLEELVALFDSGDLRTLPHRAWDVRSARQAFRHMAQARHVGKVVLTMPRP
LDPDGTVVITGGTGVIAGHLARHLVAAYGVRHLLLLGRRGRADLTGLDAPGLRVTVAACD
VSDRRQLEEALARVPAEHPPTAVVHAAGALDDGLVQSLTEDRLAPVFRPKADAAWHLHEA
TRDLDLSAFVLFSAGAGVLGSPGQGNYAAANAFLDALAVHRRAAGLPGQSLAWGVWSGAS
DMRGAYGPADADRMARGGMLPLSVADGLAAFDAALAAGDALLVPAHLTPGRMAVIPPLLS
ALGPTRGQGARPALAGSLSALPDAERLRHLTDRVMAEAAAVLGHESPDALPEGRAFRDLG
FDSLTAVELRNRLAALTGLRLPATLVFEHPTPTALAAHLHASLGGAQEARASAGTTPVAG
TGSRDEGIAIVSMACRLPGGVETPEQLWDLLAEGRDAITPFPTDRGWEPSDPAGVGGFLD
AVDEFDAGFFGISPREALAMDPQQRLLLETSWEAFERAGIDPSSVRGEAIGVFSGVWAND
YLARLGHVPQDLRGYLGNGSATSVASGRVAYTLGLEGPAVTVDTACSSSLVALHLAAHSL
RRGESSMALVSGATVLATPSVFGEFERQGGLAPDGRCKAFAEGADGTGFSEGVGVLLLER
LSDAERLGHPVLAVVRGSAVNQDGASNGLTAPSGGAQERVIRSALVAAGLVGSDVGVVEG
HGTGTRLGDPIEAGALLAVYGEGRERPLWLGSLKSNIGHTQAAAGVAGVMKMVLALGHGV
LPRTLHVGEPTSGVDWSSGGVRLLTEERVWEGPRRAGVSSFGVSGTNAHVIVEAPPEASA
REPAPDSARPAAPPVVPWPLSGRTSQQLRAQARALLTAVHDHDRTDVGHALAVTRATWEH
RAVVLADHPDALRDLAAGEPSGAVVTGEHMPGGFAFLFTGQGSQRPGMGAGLYAAWPAFA
AAHDAVTAHWEQHIPDTAELLDRTDHAQRALFAFEVALFRLYESWGARPRAVAGHSVGEI
AAAHVAGVLSLADACALVDARGRLMAALPAGGAMIAVRAPEAEVTAELPEGVCLAAVNGP
DSVVLSGDARVVEAYAEKWPRPKKLRVSHAFHSHHMDGMLDAFADVVRNLTFSRPEIALP
GDVEDPAYWVRQVREPVRFLDTLRTLRSRGIRTFAELGPDAALSAMGPQCVPDAVFVPAL
RPSGGATEPRDAVTALARLHVRGAAVDWAALLPGARPVDLPTTAFQRERYWLRDSGTGTA
PVGSGLTPDGHPLLAGVVDLPDGGRVHTGSLSTASHPWLADHVVAGTPLVPGTALLDLAL
HAADQAGAGPVDELVLREPLVVPDGRAALLRVHITPPDAAGRRTLTIASRAGDADTDPWT
TRAEGTLAAPGAGVPHEPVPSGPWPPAGAEPLEPAALYERLAEAGLAYGPSFRGLRAAWR
DGREVCAEVALTGPDADADGFTVHPALLDAALHALAPDATGLRLPFTWSGVSVAARGATE
LRVRLSLSDEGTVRLVAVDRENRPVVTVSSLTTREVPTGRRFVGGLFRTRWVPAPGPDAV
GPLVADDRLVVGSDTGDVPADVRRATRRVLAAVQDRLADGARTSPLAVVVAGAAEPVGGA
VAGLVRSAQSEHPGRFVLVHLDGPQDRLAAAVATGEPEVAVRGDALHVPRWTPAGLPDGA
PPPFDPDGTVLITGAAGAIGRAVARHLVADRGVRRLLLVGRRAPAAALAEELGELGATVT
TAACDVSDRDALARLLSAVPAGHPLTAVVHCAGVLADATVTAMTPEHLDAVLAPKADGAW
HLHELTRSMPLSAFVTFSSLAGTLGGPGQANYAAANAFLDALAGHRHRLGLPAHSLTWGP
WETADGMTAHLGRSDAQRSRRAGLLPLPADAALSLLDAALALDHPVLAPVHLNRAAPRTE
NVPYLLRDLFPTGTRPAAEPGGAWAERFAVLPEAERDRALLDLVRSEAARVLGHRAGTQI
DAYQSFTDAGLDSLAAVELRNALAAALGQDLPATLLFDHPAPVDLAEHLRGLVAPAAHGA
ALRDLDRVGAVLAGLPSDDPVRGQLRERLRALLRHFEEPAAADPADGDDLKARVLSATAD
DIFTLIDTELGDA
>A0A2K8QXJ2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MTDDEKLRSYLKRATADLRLARRQLREVEDRAREPIAIIGMACHFPGDVATPEDLWRVVD
EGVDVISSFPEDRGWDLDSLYDPDPEHAGTSSAREGGFLRDVADFDAEFFGISPREAAAM
DPQQRLLLETAWEAFERAGLTREALNGSRTGVFAGVDSYHYLSLIGQTTGDSAGYVATGN
LGSVVSGRVSYSFGLEGPAVTVDTACSSSLVATHLALQALRQDECSLALAGGVTVMATPG
GFTEFSRQRALSPDGRCKAFAAAADGTGFSEGVGLVLLERLSDARRNGHRVLALIRGSAV
NQDGASNGLTAPNGPSQQRVIRQALANAGLSPSEVDAVEAHGTGTTLGDPIEAQALLATY
GQDRPEGRPLWLGSIKSNIGHTQAAAGVASVIKMVMALRHEVLPVSLHIDAPTPHVDWGA
GEVRLLSEPVEWAANEQPRRAGVSSFGISGTNAHLILEQAPAQPVEAARAPDSSRGGVPA
GGVVPWVVSGRGTEALRGQARALAERVATDPDASPAEVGWSLISTRSVFDHRAVIVGEHR
DELLAGLNALATGDTHPTLTEPTTGPGAGGMGPVLVFPGQGSQWLGMGAGLLDTSPVFAA
RVAECEHALTPHVDWSLTEVLRGGVNAADLARIDVVQPVLWAVMISLAAVWDHHGLTPTA
VIGHSQGEIAAACVAGALSLDEGARIVALRAHALRRLAGHGAMASLTISQTHTEELLTNL
GEHAEAVGVAAVNGPGSVVISGPPEQVAHAITACEQAGHRARLIDVDYASHSAQVGEIAE
ELNQLLAGVKPVSAQVAFYSTVTGARMDTSGLDTAYWIKNLRERVRFADAVRALLHDGHR
VFIEASTHPVLTIGMQESIEEARVDAVTIPTLRRDHGGPDQLARSVARAFTAGLSVDWTR
WFPTDPAPRTIDLPTYAFQRERYWLDGEGGPGGDPAGLGLTAAGHPLLGAAVELADGTTH
VLTGRISARSHPWLAEHVVAGAVLAPGAVLVEWALRAADAVGCGGVEELALQVPLALPES
GGLRVQVVVGAAAEDGRREVRMYSSPDHPNSLDPGLDSGADTGWVCHAVGVLAPAAEAPA
PVEGLGGAWPPPGAEPLDVGAFYEQVMAAGYGYGPAYQGLKAAWRQGGDVLAEVALPDAA
GGRDGYGIHPALLDAALHPSLLMDRPEGQEDDGQVWLPFAWNGVSLWATEAATVRVRLSR
DEERQSLRLTVADTVGAPVLTVDSLVTRPAAADQLRSAAATRAVDGLFTLDWMPLPAPAT
APSPASVVGEGGWVVLGEDRLGLAEPVAAGVGADATVSHPDLEALIAAVDAGEPAPAVVL
THPYTAEGGHGDGLGAVEELLGLVRSWLRRPALADARLVIVTRGAVAAGRAGDATDDADD
TALDPSGVDPSGAGAWGLIRSAQSENPGRFVLLDLDEGHEGRAGLVEAVVRAVESHEPQL
AVRDGRVLVPRMVRAVAAPGPTTDDRGESTTGLDGGATGLDGGATGLDTDGTVLITGGTG
TLGALVAEHLVCAWGVRHLLLVSRSGPEAAGAAELTAALTELGAEVRIAAVDVTDPDAVA
ALVAGVDSAHPLTGVVHAAGVLDDGVLTTQTPERLARVWRPKATAAAHLHAATAELPLSL
FVMFSSTAGTLGASGQSNYAAANAYCDALAARRHALGLPGLSVAWGLWADASGMTGHLGE
ADRARMTRSGIGAMSSERALGLLDAAVRHGHHHLIAIDLDVRALAGRPALTLPAPLRALA
GGGTARRTAATARPHTDWAGHLAALPLEEQRRTLLNLVLSHAAAALGHSDPGRIQTERGF
LELGFDSLTAIELRNRLTAVTGLRLATTLIFDHPNPAALAAHLHSELAPEDADPLAPMLG
EIDRMESALLSVAQDETAHEALLERLRTTLSKLGALHGGGTEEGPAAGRIQDATADEIFQ
FIDEDLGRSESNGEHAHGGTR
>A0A2K8RA68|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MVNNEDKLRDYLKRATADLRQARRQLREVEERHQEPIAIVAMSCRYPGGVTTPEELWRLV
LDGQDAISGFPTDRGWDVESLYDADPDQAGASYVDEGGFLYDAGGFDPAVFGISPREAMA
MDPQQRLLLEASWEAFERAGIDPTGLRGHRTGVFAGVMYHDYTSRLDSVPEGVEGFLGTG
SSGSIASGRVSYTFGLEGPAVTVDTACSSSLVTLHMAVQALRNGECSLALAGGVTVMATP
STFTEFSRQRGLAADGRCKPFAAAADGTGWGEGVGMLLVERLSDARKNGHPVLAVVRGSA
INQDGASNGLTAPNGPSQQRVIHQALTNGRLSAADVDAVEAHGTGTTLGDPIEAQALLAT
YGQEHTEDQPLLLGSIKSNIGHTQAAAGVAGIIKMVKAIEHGVLPRTLHIDEPTPHVDWS
AGAVSLLAETTPWPETGRPRRAAVSSFGFSGTNAHTILEQAPAEEPAEDATEAPAPAKPL
DVVPWALSGKSAAALRAQAERLLAHLEADPSLSPLDVALSLTTTRAQLDHRAVVRGQDRD
TLMAGLTALAEGGMAAGVAQGSAVGGRTAFVFPGQGSQWAGMAVGLMDASPVFAARIEEC
AGALGEFTDWSLVDVLRGAEGAPSLERVDVVQPVLFAVMVSLAELWRSLGVVPAAVIGHS
QGEIAAACVAGALSLKDAARVVALRSQAIGRVLAGKGGMVSVALPVVEVRERIALWGEER
ISVAAVNGPSSVVVSGDPEALDELIASCEADEVRVRRVPVDYASHSAQVELLREELLELL
APVEPKAAEVPFLSTVTGEWVEGPELDAEYWFTNLRRTVELEGAVRRLLDEGFGAFIESS
AHPVLTMGVQETAEDAGREAAAIGSLRRDEGGLDRFWASVGEAWTRGVTVDWDGVFDGTG
AVRVELPTYAFQHQHYWLESGTSTADATPAADPVEARFWEAVEREDWQSLAAELDVDGDE
RVSALLPALASWRKQAREQSTVDGWRYRVTWKPLADGQPARLTGVWLVVAPATENTDTWT
DAVAGVLAERGADVRRIAVDTDADGREELTERLRAALAETDGIPFTGVLSLLALDGHPHP
RHPSVPAGVAAQLALVQALGDAEIGAPLWSATRGAVSVGRAEPLESPEQALVWGLGRVAA
LEHGERWGGLVDLPGAPDERALARLVTALAGAEEEDQVAIRATGLLVRRLVRAPLAATPA
VRTWEPTGTTLVTGGTGALGAHVARWLAGNGAEHLVLTSRRGLDAPGAADLRSELTELGA
KVTIAACDVADRAQVEALLADIPAEHPLTAVVHTAAVLDDGVIEGLTPDQVDRVLKVKVD
ATRHLHELTRDLDLSAFVLFSSFAATFGAPGQGNYAPGNAFLDAFAEYRRAQGLPATSLA
WGPWGEGGMAEGGVGDRMRRHGVIEMAPRSAVTALQHALDRDESVLTVVDMEWKRFVLAF
TSGRSRPLLHDLPEARDVIQDMAGDADADGAGAVALAQQLAGVPEAEQERLVLELVRTAV
AAVLGYAGADDVEAGRAFKELGFDSLTAVELRNRLSSASGLKLPPTLIFDYPTPTVLARH
LRGEIAGERSAAVAALPTAAALADDEPIAIVSMSCRFPGGVRTPEELWQLLVSGGDALSE
FPGDRGWDTEALYNPDPDAQGTSYTREGGFLTGAGEFDPTFFGISPREAMAMDPQQRLLL
EASWEAFERAGIDPATLHGSPSGVFVGTNGSDYSILMRSNTEGYEGHLATGSAASVVSGR
LSYTFGLEGPAVTVDTACSASLVALHLAVQSLRQGECSIALAGGVTVMATPGTFIEFSRQ
RGLSSDGRSKAFSADADGFSPAEGVGMLLVERLSDARKNGHPVLAIVRGSAINQDGASNG
LTAPNGPSQQRVIRQALANARLSAAEVDVVEAHGTGTTLGDPIEAQALLATYGQERPEGQ
PLLLGSIKSNIGHAQAAAGVAGVMKLVLALRHGVLPESLHIVEPTPHVDWSAGEVELLTE
AREWPETGRPRRAAVSSFGFSGTNAHAIIEQAPAEEPDEAEPVTRRPGALPWTVSGKSEA
ALRAQAGKLLAHLDADPAPRPLDIGHALATTRAAFDRRAVLVGTDRDDFVRGLDALARGQ
VVPNLVQGDSIGGKAAFVFPGQGSQWVGMAVELLDASPVFAARIDECAAALAEFTDWSLV
DVLREAEGAPSLERVDVVQPVLFSVMVSLAELWRSLGVRPSAVVGHSQGEIAAACVAGIL
SLQDAARVVTLRSQAIGRVLAGKGGMVSVALPVAEVRERIASWGEERISVAAVNGPSSVV
VSGEPTALDELVASCEADEVRARRVPVDYASHSAQVELLRDELMELLAPVQPKAAEVPFL
STVTGEWVDGTELDAEYWFTNLRRTVELEGAIRRLLDEGFGVFIESSAHPVLTMGVQETA
EDAGREAAAIGSLRRDEGGLDRFWVSLGEAWTRGVSVDWEAVYEGTGAARVELPTYAFQH
QTYWPRAADIPADESGTPSDAVDARFWEAVEREDLESLADTLAFGDDGERSSLGAVLPAL
ASWRKQAREQSTVDGWRYRVTWTSLTERQAPRLSGTWLLAVPESAATDDWTLGAIRMLAE
RGAEVRQITPTAVESDRASLTRLVREELADAGTVSGVLSLLAFDEGTAPGTDGVNAGLTG
TAVLIQALGDAGVDAPLWCATRGAVSVGRTDTVDSPEQALVWGLGRTAALEYPERWGGLV
DLPGAPDERALARLAGVLAGTDGEDQLAVRTAGVFARRLVHAPLAGAPAAGAWKPAGTTL
VTGGTGALGAHVARWLAANGAEHLVLTSRRGLEAPGAAELRDELTGLGSEVTVAACDVAD
RKAVETLLATIPADQPLTAVMHAAGVLDDGVLDALTPERFATVLGPKADAARHLHELTRE
LDLSAFVLFSGIAGTLGDAGQGNYAAANAYLDALAERRRADGLPATSVAWGRWGETGLAA
DGAIGERLDRGGVPAMAPHAAITALQRALDHADTVVAVADIQWDRFAYGYTAVRPSPLIG
ELPEVKRLRETGGPAAGEPGAGPDGSPAEALRKRLAGISRAEQSLVVLEVVRSGAAAALG
HSSTDEVGAGRAFKELGFDSLIALELRNRLTAATGQKLPATLVFDYPTPTALAEFLCARI
VGDGGTAAAPGVAELDALESALSVLDPDSEARETIAARLRDLAAKWAEPRTADAEAAEGD
GGTVTEKLQEATPDEVFAFIDKELGI
>A0A445NHK6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces netropsis|TrEMBL
MNSTNEKVVEALRAAMKEAERLRRQNRQLVTAATEPIAIVSMSCRYPGAVASPEDLWQLV
ASGTDAISGFPTDRGWDLEALHTSEVDDRGTSVSQRGGFLGSVADFDPGFFGISPREAVT
IDPQQRLLLETGWEAFERAGIDAHGLRGSKTGVFVGTNGQDYAYLTVRSLDDATGDVGTG
IAASAASGRLSYALGLEGPAVTVDTACSSSLVALHLAVQSLRNADCSLALVGGVNVMSTP
GSLVEFSRQGGLARDGRCKAFADSADGTGWSEGVGVLLLERLSDAQRNGHPVLAVVRGSA
VNQDGASNGFTAPNGPAQQRVIRQALERAGLSPADVDAVEAHGTGTPLGDPIEAQSLLAT
YGQGRERPLLLGTIKSNIGHSQAAAGVAGVIKMVMAMRHGVLPKTLHADTPSSHVDWSAG
DVSLLTEARDWPEADHPRRAGVSSFGVSGTNAHVIIEQAPADTTPAAREEPVRRPGAVPW
VLSGRTAEALRDQAAALLSRLETETRPAALDVALSLATSRAAFEHRLAVVADDGDGLRAA
LAAWAANGTAPGAVEGLAAGRAKSAVLFSGQGSQRLGMGRELYGSFPVFTEALDAVLAEL
DPLLDRPLREVMWGDDAAALDETGFTQPALFAIEVALYRLVESWGVTPDFVAGHSIGEIA
AAHVAGVFPLVDACRLVAARGRLMQALPSGGAMVAVQATEEEVLPLLTDGVSIAAVNGPS
SVVVAGEEAAVLGLAGRLAADGRKTSRLSVSHAFHSPLMEPMLDDFRTVVTGLAFTEPAI
PVVSTLTGALAEIGELCAPEYWVRHAREAVRFADGVRALAAEGVGTFLELGPDGVLSAMA
QESAPAGTPTVPVLRKDRPEETTAVTALARLHTAGVRVDWQAFFAGTGARRVDLPTYAFQ
HERFWPQASMSAGDAAGLGLTPAKHPLLGATMVMAGSDELVLTGTLSLRTHPWLGDHVVS
GMVFFPGTGFLELAIRAADEVGCASVEDLTIVAPLILPERGTTQVQIHVGGADEDGRREV
RFHSRPADAPDQDWSLHATGMLAKDERTLHFDGAQWPPHGADTVDLDGLYERYAETGLDY
GPVFRGLRAVWRRGEELFAEVALDQRVKDADAFGVHPALLDAVLHSTVFASADGDQRGLL
PFSWSGVSLHASGASVLRVRITSCGPDAVELIAVDAEGAPVVSVTSLTLRSASPQAAAAH
TRRDEMNSLFRLDWVPQTVPGNTDHTGWAVLGDDTLALADALKSAGVIALHAATLTELDP
TADTVVVPVTGDPTCVPESAHELTHRVLRLLQEWQADERFASSRLLIVTRGAVATGDESV
TDVAAAPVWGLVRSAQAENPGRLLLADLDDSADSAALLPALPGLLEADEPQAVVRAGTLR
VGRLARLASAGALVPPAGTPWRLGSAAKGSLDGLALIPCPEVLAPLTGRQVRVDVRAAGV
NFRDVLNALGMYPGEAGLFGSEAAGVVTETGPDVTGLRPGDHVMGMLFGGFGPLGIVDER
LLTPVPDAWSWETAASVPLVFLTAYYAMVDLAGLRPGEKVLVHAGAGGVGMATVQLARHL
GAEVFATASEGKWDVLRALGVADDHIASSRTTDFEHAFAAVAGDGGIDVVLNALSGEFVD
ASLRLLAPGGRFLEMGKTDIRDADTLPGVDYRSFDLGFADPDRIRQMLTELVDLFDRGAL
RPLPMKTWDVRRAKDAFRYMSLAKHVGKIVLTNPPAWDPDGTVLITGGTGGLAAELARHL
VTERSVRHLLLVSRRGPDAPGAAELREELTAHGAEVTVVASDIADRAAVAGLLAGIPAEH
PLTAVVHTAGVLDDGVIASLTPERLAAVLRPKVDAAWHLHELTRDLDLAAFVLYSSTAGV
MGSPGQGNYAAGNTFLDALAHHRHSQGLPATSLAWGAWEQGAGMTSTLDDRDVRRISGGG
MPPLSVELGLALFDAATTTDEALVVPLPIGSGSGALPSADGLPAVLRGLVTTGRRSVASS
AARASRKDLAQQLAGLGDEERLRFLVDLVRAEAAVVLAHPSPEAIAAEQEFRRLGFDSLT
AIELRNRLSTTTGIALSATLVFDYPTPTRLAEYLRDELVGADTEATGGSPAPKAAATDEP
IAIVGMSCRFPGGVDSPEALWHLIASGGDAISGFPDDRDWDQHGIGGGDLTGAGGFLRGA
ADFDAGFFGISPREALAMDPQQRLLLEVSWEAVERSGLDPAALRGSRTGVFVGVSGQDYS
TLIMRSKDDVEGHATTGLAVSVASGRLSYTLGLEGPAVSVDTACSSSLVSLHLAAQALRS
GECSLALAGGVTVMSTAMGFAGFSRMGGLAHDGRCRAFSDDANGTGWSEGVGMLVVERLS
DAQANGHRILAVMRGSAVNQDGASNGLTAPNGPSQQRVIREALASGGLSPADVDAVEAHG
TGTPLGDPIEAQALLATYGRDRDAERPLWLGSVKSNLGHTQAAAGVAGIIKMVMAMRHGV
LPRTLHVSEPSSHVEWSAGSVELLREQTAWPEGRVRRAGVSSFGISGTNAHVIVEQAPRT
TAPATRPEVVPGVVPWVVSAKSEAALDAQLDRMRSFAADGTNDAGPVDVGFSLATARSAF
EHRAVLLSSADGVVEAARGVAAVDRPLAVLFSGQGAQRLGMGRELYERFPVFAEALDAVL
AELEPLVEGSLREVMWGDDAGALNETGCTQPALFAVEVALFRLVRSWGVKPNFLAGHSIG
EVTAAHLAGVFSLTDACRLVAARGRLMQALPAGGAMVAVQATEAEVLPLLTDEVSIAAVN
GPSSVVIAGEESTVLELAGRLAAEGRKTSRLSVSHAFHSPLMEPMLEDFRTVVDGLSFTA
PSVPVVSNLTGQVATPEELCSPEYWVRHVREAVRFADGIWTLAAEGVGTFLELGPDGVLS
AMAAESVAEETVTVPVLRKDRAEETAAVTALARLHTQGVTVDWEAFFAGTAARRVDLPTY
AFQRERYWPRLADAAVVATGTDAVDAEFWAAVEREDIASLASSLEIDGDSLEAVLPALTS
WRTRRRVQSAVDSWRYHEAWRPLTGVSSAVPSGTWLVITPAGTADDAWVDAAVAALGPDA
VRLRVDGQDRGRLAEELAELSGQGAEFTGVVSLLALDGTSGATGVPAGLIGTTVLIQALN
DARIAAPLWAVTRGAVSVGRSDGLPSLVQSAVWGLGRVAALEYPGHWGGLVDLPETLDER
SARRFAAVLAGVDGEDQVAVRASGAFGRRLVPAPSGEHDKRWEPSGTVLITGGTGALGAH
VARWLARHGARHLLLLSRSGLRAPGAPELRDELTALGAQVTVTACDASDRAGLTAVLAAV
PEEFPLTGVVHASGTLDDGVLDGLTEERFEAVFRSKVAPALLLDELTRELDLSVFALFSS
IAGAVGNPGQANYAAANVVLDTLAERRRAAGLPATSIAWGAWAGDGMADRADVRTGGAVL
DPESAITALSRVVAEPAASVVLADLRQPRVLEALLSLRPSALLDELPEALRAAEAVREAR
RDSESAVSGLRQQLTNATGAERLALMLSMVRTRAAAVLGHAGAEAISGDKAFRDFGFDSL
TAVELRNQLMGATGLPLPTSLVFDYPTPRALAEHLVAELVDERADSDAPVATPAAPTDDP
IVIVGMACRFPGGVYSPQELWELLVDGRDGIAGFPSDRGWDLDLLAGGGQGASATGKGGF
LYDAAEFDADFFEISPREAVAMDPQQRLLLEVSWEAFEHVGIDPATLRGSRTGVFVGTNG
QDYANLVLKARDDVEGHAGTGLAASVISGRLSYTFGFEGPAVTVDTACSSSLVSLHWAAQ
ALRGGECSLALAGGVTLMATSTSFAGFSRQGGLSPDGQVKAFSDDADGTAWSEGIGMLVV
ERLSDARRNGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALAGGGLSPADVDAV
EAHGTGTKLGDPIEAQALLATYGRDRDAERPLWLGSVKSNLGHTQAAAGVAGIIKMVMAM
RHGVLPRTLHVSEPSSHVDWSAGSVELLREQTAWPESGRARRAGVSSFGISGTNAHVVLE
QAPLAEPPVTQGPVAVPGVVPWVVSGRTEAALDAQLEKLRSYAADGTTASSLDVGYSLAA
GRSVFEHRAVLLSSGDGIVEAARGALADRRPAVLFSGQGAQRLGMGRELYERFPVFAEAL
DAVFAELDLSLDRPLREVMWGEDAGLLNETGCTQPALFAVEVALFRLVESLGITPEFVAG
HSIGEVAAAHVAGVFPLPDACRLVAARSRLMQALPAGGAMVAVQATEEEVLPLLTDEVSV
AAVNGPSSVVVSGAEDAVLELAAKLAAEGRKTSRLSVSHAFHSPLMEPMLADFHAVVSGL
SFHAPSVPVVSNLTGRLATSEELCSPEYWVRHVRETVRFADGVRTLAGEGVNVLLELGPD
GVLSAMAAESVPEGTMTVPVLRKDRPEETAAVTALARLHVQGVPVDWTAYFAGTGARRVE
LPTYAFQRERYWPRVSAAVGDVSGLGLTSAGHPMLGAAVIMAGSDEVVLTGRLSLATHPW
LADHRVGGAVSLPGAGFAELAVRAGDQVGCDRVDTLTLLAPLTLPEQGAVRLQVRIGTPD
DEGRRPLGVYSCPEGTTGAPWTRHAEGTLTDGAEDAAAGFDATTWPPEGAEQVDLDGHYE
ESAEDGVAHGPVFQCLSAVWRRGTDVFAEAALPEQVTDAAAFAVHPALLEAVAQAAGFAM
PEETQGRLVAASFSGLSVHAGAASSVRVRLTATGADAVSLAAVDIEGAPVLSATSMALRP
AQVGETAAAAAEGVATLRIEWPDAPHAHDPVADGGRWAVVGADPFGLVDALESDGERSVR
RVDSFAQLFDGEGAVPGTVMVPVVSAGGTEALPASVRAVSARVLALLQEWSADLRLSASR
LVFVTRGAVAVGDGDVTDPAAAAVWGLVRSAQAQSPGGFLLADLDDVLVPSLVPALLARD
EDQLAVRDKAVRVARLVRVPQEVVPDARAWDPDGTVLIADGTGGLGGELARHLVAEKGVR
HLLLAGPSGPQTPGAAELAAELTAAGATVTVAACDLADRADLAALLASVPAGHPLTAVVH
TAGVHDDGALASLTPERLAEALRPKADAAWHLHEATREMDLSAFVLCSSVSGVLGSPERA
GSSAADAFLDALAQYRRNLGLAGTSVAWGPWARGSGTTPALPADTERTDRFGMPPLTLEQ
GLALFGTACDLDEPLVVSLGLTAEGTARSAGEIPSILRGLVRTRRRTAASAGRSAGLLQR
LEGVRENERAQLLTELVRTEVAAVLGHPAPDTIVADQEFRRLGFDSLTAVELRDRLNTAT
GLKLPTTLVFDHPTPLAVSEYLATALLGDSTPATALSPLAELDRLEAALSAGDPDEVTKS
GVAVRLRQLLARLTETGTETGGLAVTERIEAASTDEVFAFIDNELGRMNDR
>A0A445NC19|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces netropsis|TrEMBL
MSDTLDALDGLKCTVLIRHTDPVMRDHTVHGTSVLPGVTFLDLIHRILRARGVDTETAEL
RRVLFRRAVVASEEFDTGLEFTFTADVGRHRIVVHGVPLPRAGGRGEAATVLEAELYAGE
PFPRHTVDLAALRARATHTVDMAESYRVARGAGLVHGPFMRGLGTLHVAGDELLAELSVG
PSAREYLGHFPLHPACLDAAAILPAWFADRPDRPDGRGFGEAAAEARGPYVPVRIESFRA
RGPVGADSRVRVRLPFRGLDSCVLDPCDLDFYDADGVRQMWLHGLTSQRAHSVGVVRGRA
DALDARLTGVLRELLGVGAAGVTATDTFAELGMDYPAMAAFARRAAAELGAEPSPSFLGF
FLDGGATASSVAARLPGAGTVTRAVGAGPPTGVPVVDHPLLGTAVELPEGHLFTARLSLA
DHPWLADHVIGGSVLLPGTAFVDLASHIAHRMGVPVVEELTLSAPLALPGPHAAVTLRVS
ADAADATGRRGFAVHSRPEDAREGAPWTRHATGVLAAAGPSSTGRATWPPPAGARTVPVA
GTYERLARAGLGYGPLLQGLRAVWRQGRDVYAEVALPGPADAGGGGGFGVHPALLDAALH
AIAFGDFLTTPGTPYVPFAWSGVRLRAAPGVVGLRVRVSPAGTDAVTLETTDVTGAPVVT
VESLALRPLSTGAGDGSFFQVDWVELSAAAAGTAVRRCAVLGDSPALSAALSAAGVRVVS
APDPAALAASGTVPELVFAPCAATTTPGGEAARWALALARAWSADARFAGSRLVFLTRGA
MAVVTGDRVDDPWHAAVWGLLRSAQSEHPHGFAVADVEGYMTKVTARALLSALTTDEPQL
AVRAGVVHAPRLARWAPDGTAAGERGAADGAWRAGTGAGVIGPGPEGVSSVAGRALAPGA
EGSGRALPGRSYGTAPTAGRTAGSAVPPAAGGFTGGSRTDTVDVDAHGNRRALPSAPGPA
GPGAADAKPARPGTGPVAAFTPGGAKTPNTGWAGAGTVVVTGASGALGRLVARHLVVEHG
VRGLLLLSRRGARAPGAERFEAELAGFGAHVTTVACDVADREALAGALARVPAERPLSAV
VHAAGVLDDGVLGELTPARLDAVLRPKADAAWHLHELTRHLDLSAFVLFSSVAGVVGGPG
QANYAAANAFLDALAHHRRARGLAGLSLSWGLWESADGTAGGTAAGMGGTLDGAGRRRLG
RTGVTALAAREGLRLLDAAAASGRAHLVPVALDPSAGTGPVPPLLRGLVREPAPAPLAAL
PASGLRETLAQCVRDQAAGVLGHADAGAIASDRPFAELGFDSLSSVEFRNRLERALGAGC
PRLPATLTFDHPTPDALVEYLCGEFGSRTTAPDVTAGPSQEPIAIVGMACHYPGGVRTPD
DLWRLVATGADAVTGFPEDRGWDIGDEGTTREGGFLHDAAGFDAGFFAMSPREARVTDPQ
QRLFLETAWEAVERAGIDPHTLRGTRTGVYAGVMYHDYPGADAAGSVVSGRVSYALGLTG
PALTVDTACSSSLVALHLAVHALRRGECALALAGGVTVMATPGTFVEFGRQRGLAADGRC
KSFAAAADGTGWAEGVGVLLVERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPSGPSQ
QRVIREALADAGLSADRVDAVEAHGTGTRLGDPIEAQALLATYGRGRAPGRPLWLGSVKS
NLGHSQAAAGVAGVVKTVMALRNGLLPRTLHVDEPTPHVDWSAGDVRLLTEPVPWPGTVG
EVRRAAVSAFGLSGTNAHVIIEEAEAEETEEEPEGIPHGPLPWLLSARTREALRDQAARL
RAWARDRPALRPLDVAYALATTRSVFEHRAVVLGAGRAELLAGLDALADGAAGTGAVIGT
AVPDTPLTALARAYAGGGPVPDRAAAFAGTGARTVELPTYAFQRERYWATPPAPGTGAAH
LGLRATAHPLLGAAVTLADTEGLLLTGSVSPRTHPWLADHTVDGTVLLPGTAFVELALRA
GGEAGCDVLEELTLQTPLALPTGGVRLQVTVGGPDADGRRPLAVHSQAADADDPGSWVRH
ATGVLAAGAPTAPPAVGEWPPRGAEELLPEDVYAAMSAAGLEYGPAFRGVRAVWRQGADL
LAEVALPSGTSGFSGTEPDATAYRLHPALLDAALHPLALGLPGTGDEPGGRPRLPFAWRG
IALHASGAGTLRVRLTAGAGGAGGVRLYVHDAAGGPVATVDSLVVRPLPEGALTAGAARA
RETPLFRVEWTPLPVPLPAEPVARSVPWAVLGPDGPALTEALEAGGVRARAYEGLAALTA
EPPPGPVLVPFFPRPDADLAATARTAVRRALSLAQGWLADDRYARSRLVLVTRGASGAEP
PGDPSHAALWGLIRSAQSEHPDRFVLLDLPASTAPSDIPLAGLPAALASGEPQLALTADG
VPRVPRLVRVSAEPSGRGAVGQGAGTPHPPGPRPARATWDPTGTVLITGATGTLGGLVAR
HLVRTHGVRHLLLAGRRGAGAPGVAELADELTRLGADVAVVACDVADRAALRELLAGVPE
AHPLTGVVHAAGVLDDGVFAALTPDRLDRVLRPKADAAAHLHELTCELGIELSAFVLFSS
ASGVLGGPAQAGYAAANAFLDALARHRHARGLAASALAWGLWEERSDMTGALGAAARDRM
ARTGFLPLATEDGLALFDTAQAADDAALVPVRLDVRALRALAAHDVPPLLRGLVEPPARA
DGPGWADRLAALSGSAREQAALDLVRDRTATVLGFASPDAVETARTFQELGVGSLNSLEL
RNRLAADTGLRLPATLVLDHPTPRELGRHLLSLLPEPDRTPAPAATSTHSQDPVAIVAVA
TADRPDFDPDFFAGPAAGRLAETVWEAFESAGILPAHWSEASGRVGVFVGRTHRAPGPHA
GRVSAAYGFQGPAVTLDTTDTAALMVPHLAVQSLRRHESGLALAAEVTDAGCAVLVLRRL
SDAHRHGHPVLALVTDSAAGRGATAEAVPPGGPGLAGLIASVRAVRQGTPTLRVSAFGAD
GTHAHVVLDGAPADTAPATPTPGGRPGTAVTVCVVSAKSPDALRAQARRLRAHLRERPGL
APATVAHALATTRTAFAHRAALVTESRAELLDALTALADGKDADGKDSAALLRGETGPTP
PTPLTMRFAAHDGRRPVFGRGLYRAFGPYAEAFDATVELLDASLGRPMRDVVWYEPVLLE
KPEYGHPALFAVQVATFRLLEHLGLRPDRLTGTAVGAVAAAHAAGVLDLPDAAALAVAHG
RLVAGTPREEFERVAGRLTCRPPTVPLLSDTGRAVTDEEPASPAYWLRRTGETAPPASDV
LQLGPYGPHFGPNGPVDAASQTRALAETLGRAYVRGLALDWDALYGGGGRGVRPGRYLGL
PTYAFRRRPRGG
>A0A5B7V4Q4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MADEVQLRDYLKRAIADARDARKRLREVEDQAREPIAVVSMACRYPGGVGSPEELWRLVA
DGVDAVCDFPEDRGWDVEGLFDPDPDHAGTSYTSRGGFLRGAGLFDAGFFGISPREALAM
DPQQRLLLETSWEALEQAGIDPLSLKGIDVGVFSGVSSQGYGAGAGVVTPESEGFAGTGA
TPSVASGRVSYVFGFEGPAVTVDTACSSSLVAMHLAAQALRHGDCSMALAGGAMVMATPG
NFVAFSRQRGLAEDGRCKAFADGADGMGLAEGAGVVVLERLSVARERGHQVLAVLRGSAV
NQDGASNGLTAPNGPSQQRVIRRALANAGLSPADVDVVEGHGTGTALGDPIEAQALLATY
GRDRDPERPLWLGSLKSNIGHTQAAAGVASVIKMVQALRHGVLPPTLHVRTPTTEVDWTT
GAVELLTEAREWPRDDRPRRAGVSSFGVSGTNAHLILEEAPEEPVSEGSAPVGVVPLVVS
ARTPGALPGQAGRLAAFIETADGTPLATVAGALVSGRALLDDRAVVVADSAEDALTGLRA
LARGESGPNVVSGSVTGSGVPGDLVLVFPGQGSQWVGMGRELLDSSVVFAERVGECAAAL
ERWVDWSLVDVLRGDVDPEVLERVDVVQPASFAVMVGLAAVWASVGVVPDAVLGHSQGEI
AAACVAGALSLDDAARVVALRSQAIAAGLAGRGGMASVALSEAEVTARLGPWAGRVEVAA
VNGPSSVVIAGDAQALDEVLEALSRDGVRTRRVAVDYASHTRHVEDIQAALAEALVGVDA
KAPEVPFYSTVTGGWVAEAGVLDAGYWYRNLRGQVRFGPAVADLLAEGYGVFVEVSAHPV
LVQPITEIVDGADSAAVVAGTLRREEGGLRRLLSSMAELFVRGVAVDWRGVLPATGSARV
ELPTYAFEHHHYWLTPGEEATDAASLGQAAAEHPLLGAVVSLPQTDGLVLTSRLSLRAHP
WLADHAVGGVVLLPGTALVELVVRAGDETGCGVLEELVIEAPLAVPEHSGVRVQVAVGGP
GETGARAVEVYSQREDGPGTWTRHATGLVTAPSATAGEGPELDFAAWPPPGAQKVQVEAG
DFYDGLAARGFGYGPAFRGVRAAWRRGDEVFAEVALPEEQRKDAGRYGIHPALLDAALQV
GTFAAAADPAAEDSGEPVLAFAWNGLVLHAAGAAALRVRVAPCGPDTLSVQAADETGGLV
VTMDSLVSRPVSADQVEATADATAATALFGVDWTELPPPQSEPQAWVSVATADEAVALAG
SADVPPVAVLRAVGGDGEDAALAVTAQVLAVVQAWLAEADLEESRLVVATRGAVAAGSDA
TLTDPAAAAVWGLVRAAQAENPDRLVLLDLDPAAPEGGVESVLGPVLASREPQVAVRGTT
FTVPRLARVADQLTGTEASFGPAGTVLVSGGGSLGALVARHLVTRYGVRSLVLASRRGPD
AEGVAELVAELAGQGAAAAAVACDVSDRDEVKALLASVSTDGQPLTGVVHTAGVFDAGVI
GALSAERLAGVFAPKVDAVRHLDELTRGLDLEAFVVYSSASSVFMGAGSSGYAAANAYLD
GLMAHRRASGLPGTSLAWGTWEHATNMTTHLSSADRTRMNRRANRTGVVGIKPAEGMELF
DAALASGRSLLVPVKLDLQGVRAGAAGGGGVPPLLRGLVPAGRQQARAAAAGDGELVRRL
AGLAAAEQEALLLDLVRTQAAVVLGHSGPGGVRADTAFKDVGFDSLTSVELRNRLREATG
LKLPATLVFDQPNPLVLARHLRDGLGVSDDVLARVHARIEDVEALIGALPLDAAMKSSVA
LRLQGLVARCNGVVGRTDAATVAEQLESASADEVLDFIDDELGLV
>A0A5B7V2Y8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MRTDLIKPLPVVLLENAARFPDKVAFEDDRRAVTHGDLEARTRRLAGHLAALGVVRGDRV
ALCLGNTVATVESYLAVVRAGGIGVPLNPASAPAELEYALADSGATVVITDPVGARRLRS
SPAVPPALTLLVTGEGPEAFEGPGAHAYDRLAVTEPAEPARDDLGLDDVAWMFYTSGTTG
RPKGVLSTQRNCLWSVASCYVPIPGLTDQDRVLWPLPLFHSLSHIACVLSVTVVGATARL
LDGASADDVIKALREDDTTFLAGVPTTYHHLVTAARRNGFSAPALRIGLVGGAVTGPGLR
RDFEETFGVPLVDAYGSTETCGAITVNPPDGARVDGSCGLPVPGVGVRVVDPGTGLDVPA
GQDGEVWVSGPNVMVGYHNSPDATAEALRDGWYRTGDLARRDDAGYVTIRGRIKELVIRG
GENIHPEEVEAVLRTVEGVADAAVSGAPHRTLGEVPVAYVVPGPSGFATAELLDRCRERL
AAYKVPERVHEVTAIPRTASGKTRRLLLADRPSRLRYAASGRHEGLLSLDWAPVATPADP
RPPARTWAVAGPSAAGLATALEAAGAAVRHYPDLAAVQAAVAAGDAAPEVTVVVRPSPPV
DAPTAGRAGPPDAAHGAIAREPVAEGRAAARLLAGQLRAWPPGPEPAAARLVVLTRAAVA
ATGQDGARDLAEAPLWAVARSLQEQGADSLTLLDLDADATPETLFAALASGEPRIAVRSG
ALLAPRPSRLPVEDVPGVAAWTGATGTVVVTGADTEHGAALAHRLATVHQVEHLLLVDAP
ADTGTPSAAAPAPTGTDTVRVAADGRDPEPLRAALAGLRRPVSAVVHAAGDPELALFLDE
LTAEAEPVPFVAVSGAAALLGTPGTTDTAVDEALTEAVVHGRRLRGLPGTFLARVGEPGA
AGPADEDTGWARAAFLTAFDLALTTDPATLLTLDPSAPADVRRLPAPLADLAGPEQTPSR
RREPDAAVTAALRDRLAAMDERAQQALLEDLVRTRAAAVLHRPGPEPIPSDRAFRDLGFT
SMAVVELRNRLTESTGLPLPTTVVFDHPTPQALAARLRAEILGVARPVTGAAPTADPGEP
LAVVGMACRLPGGVTGPEDLWRLVSEGRDAVSGFPEDRGWNLEGLFDPDPDRAGTSYTDQ
GGFLHEAGLFDAGFFGISPREALAMDPQQRLLLEASWEALERAGIDPGSLKGADVGVYSG
VFGQGYGATGTGVVAPEAEGFASTGSAGSVASGRVSYVLGFEGPAVTVDTACSSSLVAMH
LAAQALRQGECSMALAGGATVMATPGTFVEFSRQRALAPDGRCKAFSSTADGTGWAEGVG
VVVLERLSVARERGHRVLAVIRGSAVNQDGASNGLTAPNGLAQQRVIRRALASAGLAPAD
VDAVEAHGTGTALGDPIEAQALLATYGQGREPERPLWLGSLKSNIGHAQAAAGVAGVIKM
VQALRHGLLPATLHVDAPTPQVDWSVGAVELLTEARDWPRAGRPRRAGVSSFGVSGTNAH
LILEEAPEEPVAEDCGPLGVVPLVVSARSRASLAGQAGRLASYVESGAGESLPAVAGALV
SGRAVLGERAVVVAGSGEEALTGLRALARGEHAAGLVTGTGTPGKVVWVFPGQGSQWVGM
GRELLDASPVFAERVAECAAALERWVDWSLVDVLRGDADPEVLERVDVVQPASFAVMVGL
AAVWASVGVEPDAVLGHSQGEIAAACVAGSLSLEDAARVVALRSQAIAGELAGRGGMASV
ALSEAEVLGRLGPWAGRVEVAAVNGPSSVVIAGDAEALDEVLEALSRDGVRTRRVAVDYA
SHTRHVEDIQDVLAEVLAGVSAKAPDVPFYSTVTGGWVEEAGILDGEYWYRNLRGQVRFG
PAVADLLREGYGVFVEVSAHPVLVQPVTEAVDADAVVTGSLRRDEGGLRRLLVSMAELFV
RGVAVDWRGVLPMTGSPRVELPTYAFEHQHYWLKPVAEATDAASLGQAAGEHPLLGAVVA
MPDSGGLMATSRWSLRSQPWLGDQLAGDVAVVPNAALVEVAVRLGDLVASPVLDELVVEE
PVVLPHRGSRGVQVVVGGPDGSGRRSVEVYSRAGDAPLDARWTRHAYGTLSHGTTTEVTP
PRSGPVTEVALDGAALREAGRYGVHPALLDAAVRTVVPDGMVASVWTGVTLLASGATALH
VRAGGTSPDGTGLRLTDPAGQPVMTVASVRGAVFTSEQAGVAAEVARDALFRVDWTELTL
PAVDRALDVVTVAGAEDVGACAGPGTSVPEVVVYEATRATADPRPPVNAALAVLQAWLAE
PALAGTRLAVVTGDRTELGAAAVWGLVRSAQSEHPGRIVLVELDEDSRGALPAVMLSGEP
QLRVRGGVAAVPRLARVPVPESGAGRQPRPLDPEGTVLITGGTGTLGAATARHLVAAHGV
RHLVLASRRGAAPELREELAGLGASVTVAACDTADRDQVAELLRAIPAARPLTAVVHAAG
VLDDGVLTELTPERVDTVLRPKTDAALHLHELTRDLDLAAFVLFSSAAGVLGNPGQANYA
AANAALDALACQRRRAGLPGVSLAWGYWATASGMTAHLGAADLRRNQRVGMSGLSAAEGM
ALLDAALLDAALLEASLRTGADDPLVAAKFDVAALRTAAAEGPLPPLLRGLAPRPRPTAR
AAAPAGPASLRERVAALGATERTEALVDLVLGHAAEVLGHSTADAVRADRTFKEAGFDSL
TAVELRNRLAAATGLTLSPALVFDYPKPTALAGHLGSQLLGVPSDRPAEPAAPARTADEP
IAIVAMACRFPAGAHSPEDLWRVVAEGTDAVTEFPDDRGWDTDRLFHPDPDHAGTTYVRH
GAFLDDAAGFDAAFFGISPNEALAMDPQQRLLLETSWEAFERAAIDPGTLAGQDVGVFVG
VNSHDYSVRLHQAPGAAGIEGLRLTGGSGSVASGRVAYHFGFEGPAITVDTACSSSLVAL
HMAAQALHRGECSMALAGGVMVMGTVETFVEFSRQRGLAPDGRCKAFADGADGTGWSEGA
GLLLVERLSDARRRGHQVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIRKALAHAGLGTS
DVDAVEAHGTGTTLGDPIEAQALLATYGQDRPAERPLWLGSVKSNIGHTQAAAGVAGVIK
MVMAMRHGTLPRTLHVDRPSSRIDWSAGAVELLTEAREWPRDGRPRRAGVSSFGIGGTNA
HVVLEEAPDPEVPDSEVPDPEVRDSEASGQVATGPQVSGQQVPGPPVPDHAAAVEPEPGA
RRADGPPPAPALVPDPASVPVLVSARTPDGLRGQAGRLARFLDDRPDVRLADAAHALATT
RARLDHRAVVLASGRGQAGADLRAFGRGEESPAVVSGTPVPGKLAVLFTGQGSQWPGMGR
ALAAAHPVFRDAFAAACAAVEAHLGGHAARPLHEVVFAEHGAPGSELLGRTMYTQGALFA
LETALFRLFESWGVRPDLLAGHSIGEITAAHVSGVLGLAEAGELVAARGRLMQALPADGA
MVAVRATEADVEPLLARARGTVCVAAVNGPDALVLSGTEDAVLALADELARQGRKTRRLP
VRHAFHSPLMEPMLDEFRTVAERLSYRTGELPVVSTLTGALARDGRLATPGYWVDQVRGT
VRFGDAVTALGGLGATTFLELGPGGALAAMALGTLGAPERSCVATLRKDGAEAADVLTAL
AELHVRGTAVDWTAVLAPPATAAGADLPTYAFQHQRYWVDSDSAAPAGAEALGATGARHP
LLGTVIDVPGDDGGSGGVVLTGRLAPHGPGRLPGPKGADGTTAIPAAVLLDMLVRAGDEV
GCGSLEQVAVEEPLTVPGRSHTHVRVSVAAPAPDGRRHATVHGRPAGPEQGPWTCHARAV
LVPGTPHPAFDVRTWQPPEDNTALLAGARVWQQGDHTCAEITLPSELADETDRFTLHPVL
VDTALRVLAARTGADPAADADDLADCAGLAVYAEGAASLRLRITPGRDGRHLLELADPDG
EPVAALGPLSLTAPAGRGAAPASCVGGTADAPAATGAVARRVVARREGAEAAFADRLAGL
SAAEQHRVVLDLVQESAAVVLGHRAQDRFDEDQPFKNLGFDSLGAVRLRNRLRDFTGVEL
PSTLVFDHPTPALLAAFLRAELLGERPDTPAPGPAAIADEPIAIVAMSSRLPGGADSPEE
LWTLLVEGRDAISGFPVDRDWDLEGLYHPDPSHPGTSYTRSGGFLHEAARFDAGLFGISP
REALAMDPQQRLLLETSWEALERAGVDPLSARGGDIGVFTGIVHHDYVTRLHQVPEDVQG
YLMTGTASSVASGRVSYVFGFEGPAVTVDTACSSSLVAMHLAAQALRQGECSMALAGGAT
VMASPDAFLEFSRQRGLAADGRCKAFSSGADGTGWSEGVGVVVLERLSVARERGHQVLAV
IRGSAVNQDGASNGLTAPNGPSQQRVIRRALDAAGLTPADVDVVEAHGTGTALGDPIEAQ
ALLATYGQGREPEQPLQLGSLKSNIGHTQAAAGVAGVIKMVMALRHGLMPPTLHVDEPTT
EVDWSAGAVELLTEARAWPREGRPRRAGVSAFGASGTNAHLILEEAPAEEVWPAPGQSGV
VPLVVSAHSAGSLAGQAGRLASYVESGAAGVPLAGVAGALASGRAALAERAVVVADAPAE
ALAGLHALARGEGGPNVVTGSATGSGTLGKIVLVFPGQGSQWAGMGRELLDASAVFAERV
GECAAALEPWVDWSLVDVLRGDADPELLERVDVVQPASFAVMVGLAAVWESVGVRPDAVL
GHSQGEIAAACVAGALSLDDAARVVALRSQAIATELAGRGGMASVALGEEDAAARLERWA
GRVEVAAVNSPSSVVVAGDAQALDEALAALDAEGVRTRRVAVDYASHSRHVEDIRATLAE
ALDGVNAKAPVVPFHSTVTGDRVADAEVLDGAYWYRNLRGQVRFGPAVSELLRQGHGVFV
EVSAHPVLVQPVTEAVDGADAEAVVTGSLRREDGGPRRLLASMAELFVRGVAVDWSAVLP
AGTAAAARSARADLPTYAFDHQHFWLREAAADDDTADAAEGADADFWAAVEHADVDSLGA
LLDTAAADQLGALNTLVPVLAEWRGRRRRMSTAEKLRYHVTWQPLAHEAAGVPGGRWLVV
VPAGRSDDSGTDALLAELTGLGLTAVSLEVGAADGTRERLAERLGAVLAEHDVTGVLSLL
ALDRGARGGPQDPAAVTASSLALIQALGDTGATPPLWCLTRGAVNTGIHDTLTSPAQAAL
WGLGRAAALERPDRWGGLIDLPAATGPRTARQLLGVLNSAAGEDQLAVRRSGAYARRLVR
KAAPDTTGDGGWRPRGTVLVTGGAEGLGRHVCLWLALAGVERLLVTTTAHAPDGSVPELR
AELAASGLPAVVETCADTDRDALARLLAAKDPERPLTAVVHAADLTWTSAVDDTGAHDLA
EVFAAKVDTAVWLDALFEDTPLDAFVVFSSIAGVWGGGGQGPSGAANAVLDALVERRRAR
GSRATSIAWGALDGIGVGMDEAALAQLRRRGVLPMAPQLAVTAMAQAVRGNEKSVTVADM
DWRAFVPAFTSVRPSPLLADLPEAQAVLQAAGDDGQDSGTAASLADSLRAVPDAERNRLL
LRLVRGHASTVLGHGGAEGIGPRQAFQEVGFDSLAAVNLRNSLHAATGLRLPATLIFDYP
TPEALVGHLRTELLREPDDGLAGREDDLRRVLASVPLTRFKEAGVLDALLGLAEAEAEAK
AEARATTGLPTAADAELIDAMDVAGLVQRALGKTS
>A0A5B7V4F4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MSDFEEIAAHSHPEARPHPEDASRAAAPAADDASRPVVPAADDAPDPAAPAPATDLRAAL
EGRPRAEQERRLRAVVTGEVVAVLGGADGERLSGDLSRPFLDLGLDSLTAVELHRRLQRA
TGLKLPVTAVFDYPTADALARHLRAELFDSADDGYVPAARRADDEPIAIVAMSCRLPGGV
ETPEELWQLVADGVDAISGFPADRGWDLSALYDTDPDRPGTSYVREGGFLHDAGEFDADF
FGLSPREALATDPQQRLLLEASWEALERAGIDPASLRDSGTGVFVGAETQEYGPRLSDAG
DGLEGYLVTGTAASVASGRIAYTLGLQGPTMTVDTACSSSLVALHLAVQALRQGECALAL
AGGVVVMASPGSFLAFSRQRGLAPDGRCKPFAQGADGTAWGEGVGMLVLERLSDARRNGH
EVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIRAALADAGLAAADVDAVEAHGTGTTLGD
PIEAQALIATYGKDRPEDRPLWLGSLKSNVGHTQAAAGVAGVIKMVQAMHQGVLPKTLHV
DEPSSHVDWSAGAVELLTEAREWPERADGPRRAGVSSFGMSGTNAHLILEQVPSSTEAGG
QADGADGPGAAVPSGAAVPSDVTAQEEVSGRPDEAGRSDASGEPGVFGPADGVGQPDAAG
QLDGAGASGGAGLLDGVGPSDGFGPRDGFGPRDGFGLPGGFGQPDAFGQPGGAGASGGFG
PAGGSGLSSVISGRVPLALSAKSEDALRAQAARLRERLLARPGLEPLDVAWSLAVTRSRF
ERRGVVLGRDRDELLAGLERLADGDLGAGGAVTGRAVPGAARPVFVFPGQGSQWAGMARE
LLDESPVFAARMRECADALGPFVDWDLFDELDGGNFDRVDVVQPVLFAVMVSLAAAWRAA
GVEPAAVVGHSQGEIAAACVAGALSLEDAAWVVALRSQAIIELSGLGGMVSVPLPERQVR
EILTQWGDDLSVAAVNGPAHVVVSGAAAALEELVAQCVARDIRARTIPVDYASHSAHVEA
IEEHLERVLAPVAPRTPDVPLYSTLTGDWLTGDTLMDAGYWYRNLRQTVLFEHATRGLLA
EGHGLFLEMSPHPVLTVPVQATIDATDSQAATLGSLRRDDGGADRLAASLAEAHVHGAEL
DWQALLPGERTVVDLPTYPFQRRHYWLTEERTDGATPLAAATDEAEALFWEAVEREDVDE
LSSTLGDVAQGALSEVLPGLSAWRRRRRERSTIDAWRYRATWQPLPGAALPPARLAGPWL
VVLPDTARAHPWATGVTEALTAAGAEPVVLSLDTGEATRAHLAELLRRAADNGAPEPVGV
VSLLGLDESPLDGHEAVPAGVAGTLALVQALGDTGATARLWALTRGAVSTGRSDRLDHPL
QAHLWGLGRVVALEHPDRWGGLIDLPRDHDARAGTRLAAILAAAHDGGEEDQLAVRGSGV
FARRLVRGEATGADLTRDTRWTPRGTVLVTGGTGALGGHVARWLAREGADHLLLTSRRGP
DAPGAAELSAEIEELGARVTVAACDVADRDALAGLLDDISADTPLTAVIHTAGVLDDGVV
DALTPERLDGVLRPKSPAATALHDLTRDLDLDAFVLYSSASGALGNAGQANYAAANAYLD
ALAEQRRADGLPATSVAWGTWDGAGLADTAVRADRSRRDGMPPMPPAPAVAALRDAVERG
DATVLVAAVDWDTFLPGFLAARPNRLFDTLPEVRGRSADPAPAEAGAGHAVTGPDWIRRL
APLPGTERGTALLAFVRTQAAAVLGHSSPEAVDPGRAFRELGFDSLTAVELRNRVQAATG
LRLPASLVFDYPNSTSLAAYLGEEAFGAAPETGGAPAPVATAVGTDGDPIAIVSMSCRFP
GEVRSPEDLWRLVADGRDAMGEFPADRGWDLAELYDPDPDRAGKSYVREGGFLPDAGEFD
ADFFGISPREALAMDPQQRQLLETSWELFERAGIDPTTLRGTRAGVFVGSNGDDYISRMA
AVPQDIESHVLTGNAVSVMSGRLSYAFGLEGPAVTVDTACSASLVALHLAAQALRQGECD
MALAGGVTVMASPDTFVQFSRQRGLAADGRCKAFAEAADGTGWGEGVGLLLLERLSDARR
NGHEVLAVVKGSAVNQDGASNGLTAPNGPSQQRVIRAALANAGLAAADVDAVEAHGTGTT
LGDPIEAQALLATYGRERPEDRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMREGVLPPT
LHVDRPSTHVDWSAGAVELLTEAREWAGSADAPRRAGVSSFGVSGTNAHVIVEQAPVEEP
AEVVEPVAPVTAVPWLVSGRSEEALRAQAERLRDHVAGDEGLDPVDVGWSLLSARAVHEH
RAVVLGLGREELLTGLEAVASGGRGAVTGSVVEGRLGVLFTGQGSQRIGMGRELYEAFPV
FADALDEVCAHVDPWIERSLQSVMFGADAELLEQTGYAQPALFAVEVALFRLAESFGVRP
EIVGGHSIGELAAAYVAGLWSLEDAAQLVAARGRLMQALPEGGAMLAVQATEADVLPLLS
DRVGVAAVNGPAQLVLSGERAALEALEGTLRDQGRKVKWLKVSHAFHSPLMDPALDDFRK
VAAKLTYQDPTLPVVSNLTGELADPAELKDPEYWVRHIREAVRFHDGVKALAGQGVTTLL
ELGPDAVLTAMAHDTLTEPAAQAGLVAAVRKDRPETDTFLAALAQLHVRGIGVEWTPLYA
PVESRRRVELPTYAFQRDHYWLDLTEFAATGAGAGGVAADEVEARFWEAVEAEDLESLSA
ELGGGADGGALGEVLPALSSWRRQRRETSTVARWRYQEAWKPLTGLAPAAFDGTWWVVVP
ADEDAYPWVAAAVAGLEERGARVTRIAVAPDEADREALGRRLRELLDVQGESAPPRGVLS
LLALDESEGSAHPTVSAGLEGVLALLQALGDADVAAPLWAATRGAVATGRSDRLTAPRQA
PVWGMGRVAALEQPQRWGGLVDLPPHPDERARLRLADAVGAATGEDQLAVRGSGVFVRRL
VRTVAGDAPAGEWTPSGTALVTGGTGALGGHVARWLAREGAEHLVLTSRRGADAPGAAEL
RAELEGLGVEVTIAACDVADREALARLLAEIPESVPLTGVFHTAGVLDDGVLDGLTAERF
ATVFRPKVQAALNLHELTRDSEHLTAFALFASVAGSMGIGGQGNYAAANAFLDAFAAHRR
ELGLPALSLAWGPWAGGGMAADGGVVEQRVRDSGMPAMEPGLAVAAMAAALADATAPGGA
AAVTLADVVWEQYAPGYATARPCHLFDQLLPAEPAGPGDPSGKRAAGPERAGDLSTAPLA
ERLAALPAAERERAVLDLVRDRVATVLGYPAGKTVDAARPFKDLGFDSLTAVELRNLVGA
AGGLHLPATLIFDHPTPAALAQYLRGELLGGLEPAGAESPAAAPAGAGVPDDGDPIVIVS
MSCRFPGGVRSPEDLWRLLRDGADAMGDMPDDRGWNVAELYHPDPDHPGTSYVREGGFLH
DMAEFDADFFGISPREALTMDPQQRLLLETAWEAFERAGIDPATLRGSRTGVFSGTNGQD
YEHVLRAAPDGGEGYLGTGNAASVVSGRLSYAFGLEGPAVTVDTACSSSLVAMHLAAQAL
RQGECDLALAGGVTVMSTPDTFIEFSRQRGLATDGRCKAFAEAADGTGWGEGVGLLLLER
LSDARRKGHEVLAVFRGSAVNQDGASNGLTAPNGPSQQRVIRAALANAGLSAGDVDAVEA
HGTGTTLGDPIEAQALLATYGQERPAERPLWLGSIKSNIGHTQAAAGVAGVIKMVLALRE
GVLPQTLHVDRPSSHVDWSAGAVELLTEAREWAERGDAPRRAGVSSFGVSGTNAHVIVEQ
APVAESAEVVEPVAPVTAVPWLVSGRSEEALRAQAERLRDHVADDEALDPVDIGWSLLSG
RAVHEHRAVVFGRERDEFLTGLEALVPGTVAEGRLGVVFTGQGSQRIGMGRELYETFPVF
ADALDEVCAHVDPWIERSLQSVMFGTDADLLEQTGYAQPALFAMEVALFRLAESFGVRPE
IVGGHSIGELAAAYVAGLWSLEDAAQLVAARGRLMQALPEGGAMLAVRVAEADVLPLLDG
LADRVGVAAVNGPSQVVLSGERGALEGLEEILRGEGRKVKWLKVSHAFHSPLMDPALDDF
RKVAAKLTYQDPTLPVVSNLTGELAEPAELKDPEYWVRHVREAVRFHDGLKALRAQGVTT
FLELGPDAVLTAMAHDTVTEPEDQAGLVAAVRKDRAEPDTFLAALAQLHVRGAEVDWTPL
YAPVGARRRVALPTYAFQRRTYWPRAAVGAPGDMAATGLVAAGHPLLGAAVPLAGGDGYL
LAGRLSLATHPWLADHAVAGRALLPGTAFVELAVRAGDEVGCGVLEELTLAAPLVLPERG
AVQLQVSVGAEDADGRFPVSVHSRDAQDPEGPWTRHASGFLAAADGAAEPEGLTVWPPRD
AEPIDDAASLYDRLAGTGYGYGPVFQGLRAAWRRGDEVFAEVALPQEQAADATAFGLHPA
VLDAALHSTLLLGEEREGLGLPFAWSGVRLHRAGAATVRVRLAAAGTDAVSLTLADQSGQ
VVATVDSLVSRPVSAEQLGGGAVSDSLFHVEWKPQLLTPSADPVPYVSYEAVATGGDVPE
AVVWHSGVSAGEPRPDAVSARLAEALGVVQDWLADERYESARLVVVTRGAVPADGTEEVP
DPSGAAVWGLVRSAQVEHPGRFVLVDTDTDIDIDGGVDATALGAVLASGEPEAAVRGGSL
RVPRLTRTAAAPATTDATPWGEGSVLVTGAFGGLGRLVTRHLAAHHGVRDLLLVSRRGEA
AVGAGELRDELQALGTKVTVAACDVADRDAVAALLDERGADLSAVVHVAGILDDGVVTAL
TPERVDAVLRPKADAALHLHELTADLDLSAFVLFSSAAGVLGSPGQANYAAANCFLDALA
GARRAQGLPATSLAWGVWAQESEMTEGLGDADLRRMARGGVAPLSTREGLALLDSAVTLT
GPDAPAVLVPLHLDTASLRASAGPDGVQPVFSDLVRTPARRVGRALARSGGAAEANGTGP
ALVRELAGLSGADRERALLDAVRGNVATVLGHSGPEAIGATRGFLELGVDSLTAVELRNR
LNSLSGLRLPATLIFDYPSPAALAAHLDETLPRGGGTADGAEGPRAGGLAAELAGLEAAL
AAGPLADDQRTEVRGRLRALLGKLDAGEPGEADAAGIAEKLEDADDDDMFDFIDNELGVS
>A0A3N6GHX0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI97-07|TrEMBL
MAGFNQILFTSRLSLQSHPWLADHVVLGSPVLPASALVELAIHAGDLIGHPALDELNLQV
PLVLPHEGNIQLQVRAGTPDDTGRHCLCLYSRPDDFDAPWTMHAEGWYLTEEPETAASLA
WDDKTTGRTTEIQLPEGLRTDAGRYGLHPVLLQAALPTRPEDPASGTVPVPADWYGVRLH
ATGATAVKARVAEIDDDSYSLQLADAAGNLVVSVESVVFRDIPNEQFTAAVGGDSTGRES
LFHLDWTPTALPETAPPLAWAVLDPDTTGENRYPHPRAVADALASGTHLDAVLLPWPPEH
PGADRIAATHTATRTMLKLVREWLADERLEETRLVVVTSGAVATRDGEDVTDLAGAAVRG
LLRSAQSEAPDRIVLIDTDTDTTAHADITAPQALPALLAAGEPQAALREGRTLLPRLRRV
PATGTHTGRAPVWKHGTVLITGGTGTLGAEFARHLVAEHGATRLLLLSRTGEQADGAAGL
LDDLRGIGAHVTVATCDASDRDALARVLADIPQEHPLTAVVHTAGVLDNGLIPALTDDGL
TDVLRPKADAAWHLHELTRDLELEAFVTFSSTVGVLGGPGQANYAAANAFLDALAAHRHA
QDLPATSIAWSLWQLGGINAHLTESDLNRFARDGFRPIARVEGLALFDRATADSRAALVA
TPIGVSAVRAQTRIPALLSELAALPGRRVAHSGPAGPSADDPAAGLAARLGELSEAEQEH
LLLTLVRTDVAAVLGRTDAQSIAPGRAFQDLGFDSLTAVDLRNRIGTATGVKLPATLVFD
HPTPAALVGYLRDRLTPQEPDAHRTLLDELDRMERTLAAAPQDDQGRSAVSARLRALLSR
VEETGATAPAPGTGLPDPSDAIESASVDELLSFIDNELGNPAT
>A0A1S7PGN8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Agrobacterium tomkonis CFBP 6623|TrEMBL
MSNIRKMTQFFLRTVDELLVAVKGNSAVAVAVAPVVLAPALSAEDQARIAVLEGITEERL
IRELTDIVSERTGYPVDMIGDQMDLEADLGIDSIKRLEIFGAMFDRLSNGTRLLEDADKN
RNDENFDIETMSNIRKMTQFFLRTIGELLADIKGPSPVVAAVSETAVPTAPASAPAAAGA
SVVTLQRLGVVTSTKLSDIGDEEISQSKKASAEQDASAFPAQPLNAGPSVHRQRVVRQDL
ARPDRTSLTLGAERIWLLVDDGKGLSEALASRLVALGEKVARLQLSAPAKPAKGKRTAKQ
SSSGLAMEGLRDYNLQDRGRVAIEAMIAEIEQAEGPIGGFIHLQPVTAVESIGDVFPEAG
YEAAETLFTLAGVLQPRLTGTAARSSFFIASRCDGSLGTSGRGLFNAIGASFGGLSKSLS
VEWDDVFCRFVDIDPALPDEEAAGILIEELEDPQTALAEVGRGPDGSRMTLTNQAEPAMD
QPETALDADSVLLVSGGARGITADCVIALAERRPVRFALLGRTDINAPLPSWAEGIEGDE
ALKAAAIAAMQAEGEQPTPVKVEKMLNGVRHAVQIRQTLAKIEQLGGKAAYFACDIADTK
DVERTVTTVEETFGKITGIIHGAGLLADKRIEKKTGEDFHAVFHTKVRGLQNLMRALQPD
AIRQLVLFSSVSGFFGNAGQTDYAMANEALNKFAHIFKAHYPDAFVRSIGWGPWDSGMVN
DVLKKAYGERGLAIIPVKTGTRFFAEEFGSGDGPQILVGGDSYRAAKTVKTKVASRLVER
RVDLTTAPFLADHVVDGRYVLPATAAASWLVKLAEDMLPGYRFETLLGFKVLKGVTLEAG
ETCLLEAQIEPAAEASCPVAGDRHALTISVHSRTGSERQNRYMGTVVLSRELSLRPRLGA
FDLGKDDEPLGYPLYGTPQEGPLLFHGPSFRGLREVLNGGDHGLTLACELKPVEEAMQGQ
FRTTSFNAYLGDVFMQAPWLWLILGSDYAGLPSAIGRVDQFAALGFGQPFFLSMTIKSLT
QASLLVDIAVHDETGQLYFRLSDVQFTVSRQLRERLVGREDKVEAAE
>G3J042|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Methylobacter tundripaludum (strain ATCC BAA-1195 / DSM 17260 / SV96)|TrEMBL
GVRPDAVVGHSVGEYVAACVAGVFNLDDALKLLAARARLMQALPTGGAMAAVFAGEARVA
QALAGHDRLAIAAVNGAENVVISGDETALNHVLDELQAENIGHRRLSVSHAFHSPLMEPM
LAEFAKIAAEIHYHAPSLPLISNVTGRLIGEDIATPAYWVEHIRRPVRFADSIDTLHDRH
CQLFLELGPHPVLLGMTRHSCPDAILIPSLRQQTADDEQFLRSLGDLFVQGVAIDWNAVY
PKQTYQPLHLPTYPFQRQRFWVDSNRELPSAPSSRLVTLLQSGNADALTQYLQTQQALSA
DELKLLPKLSGLLIRQHRDATVNTDGLCYRPIWQEQARNAEPAMPPAGAQNRPWLIFSSG
DESELAQSLQNLGQPCIRATAGNAYAQTASDAWTVAADSADDYCRLLEATQPQTIAYVWP
SELTAHYGEDALMQTILLARAAAGLQSLTKLWLITRDATNAGDRAPSSPFPSLLSGLGRS
LFLEYPNLKGGMIDLEADETPALLRELLDSEDEDAISLRVGKRYVARLEAFQPTVAAPSR
FKADAAYLITGGLGALGLKTARFLAENGAGQLILLGRKGANENTRETLDFIEHLGTQVRV
VQADSGDETAMSELFKQLAAGNFRLKGIIHAAGVLGSCALSELDRACLHQVLAPKVRGAW
TLHRLSLDLELDFFVLYSSISSILGTAQLAHYTAANGFLDGLAEYRRGLGLPALSINWGP
WQSGGMIDGETARRIADSGFHTLSAPIALDLFGRLLAAGQTRVAVLDADWPRLKSLYEVR
GRQPLLALLGQNTTGTATVLNGLQDRSAQRIGKEHLSEEELLAALFGEVLGLDSVSVDDS
FFALGGDSLLATQLVSRVREAFALELPTKMLFDAPTVAQLLMCLRDLRGARAPLTALPRP
ERLPLSYAQQRLWFIHRLEGPGSTYNIPIALRLTGHLDADALDSALLDLLARHEALRTRF
PEFDGIAAQEIVPVADIAARLTRCQVTKAELAASLQQAAETALDITVDLPFRAWLFSSAA
GEQVLLLLVHHIAADGASMAVLSNDLSSAYAARCLQQAPQWPDLPIQYADYALWQRQVLG
AVDDPTSPMAQQLAFWQQALRGLPDELNLPTDRPRPLVSSYRGGALPIHLSAELHRDLLA
LAQAEQASLFMLLQATLAALLSRLGAGEDIAIGAPIAGRTDQAIEGLIGFFINTLVLRTD
LSRRPSLRTLLQRVRAFDLDAYAHQDLPFELLVDALQPTRSMARHPLFQVMLILQNTAKP
RMDLPGLTVSLEPLAHTGAKFDLTVDLTEQFGENGEPLGLSGELEFSSDLFDASTIELLI
QRWLRLIEQAVAEPDAPLYRCDILTPDERHTLLEAFNPIALPTPAATLPELFEAQASSNP
AATALVFADYELSYAELNARANRLAHALIEQGAGPESLIGLCLDRSFELIISLLAVLKSG
AAYLPLDPEYPMARIEAMLKDAAPLLVITATKMADILPESCARLLLDDPATLVDLAMKPR
TNPTDTDRLMPLDPRHPAYVIFTSGSTGRPKGIAICHSALSAFLASIKSAVHCDAADRFL
SVTTIAFDIAVLELFLPLSQGACVLLTARSESKDIPAFAQFFARHRPTLMQATPSHWRAL
LEALPDIEPQLQAICGGEPLPLDLAQALLAKTRSLVNLYGPTEATVWATQQAITESTLAL
QRTPLVDIGTPLDRYRIYLLDATLEPVPVGVAGELYIAGAGLARGYLNRPALTAERFVAD
PFSPMSGARMYRSGDLARWRDDGNLEFLGRADSQVKIRGFRIEPGEIEAVLLALPGVAQA
AVVARDDGLGLQLVAYWVPSASSDASDASAETLRPALAAQLPDYMLPSAFVVLDALPLTP
NGKLDRRALPAPERGGAVFVPPSSQEETLLAALFGEVLGLDRVSVADSFFALGGHSLLAT
RLVSRVREAFALELPIRALFEAPTVAQLAGRLRDLRSARLPLQALPRPERLPLSYAQQRL
WFIHRLEGPGSNYNIPIALRLSGHLDADAFDSALLDLLARHEALRTRFPEFDGIAAQEIV
PVSELTSLLTRCPVTEAELAVQLQQAADTALDITVDLPFRAWLFSSTPLSTGSLANEEQV
LLMLVHHIAADGASMAVLADDLTLAYSSRCMQQAPAWPDLTIQYADYALWQRQSLGAVDD
PSSPMAQQLAFWQQALRGLPDELNLPTDRPRPLVSSYRGGALPIHLSAELHRNLLALAQT
EQASLFMLLQATLAALLSRLGAGEDIAIGAPIAGRTDQAIEGLIGFFVNALVLRTDLSGR
PSLRTVLQRVRAFDLDAYAHQDLPFELLVDALQPTRSMARHPLFQVMLALQNTARPRMDL
PGLNVAMEPLARTGAKFDLLVSLAEQYDADGEPLGLWGELEFSSDLFDTDTVEHLSRRWL
SLIEQAVAEPDAPLYQCALLTPEERHALLEGFNATARPIPDATLPALFEAQAASNPAATA
LVFGDQELSYGELNTRANRLAHALIAQGAGPESLIGLYLDRSFELVISLLAVLKSGAAYL
PLDPEHPTARIEAMLEDATPLRVITTAALADNLPADCPRIVLDKLTDLAQRQENNPSDAD
RLAPLTPLHPAYVIFTSGSTGKPKGVLIAHHALVNHMRWMQHAYPVVPQDRVLGRTAPTF
DASVWELWLPLLSGATQVLISTQQLHDAQLLFEQLDRQQVHVAQFVPSLLASFLSEYDLK
PQALRQVFSGGEALSTELTRRLTEQWQVEVINLYGPTETTIQVTHYAAQDNALNGSTTPI
GAPIWNTRIYLLDQALEPVPVGVAGELYIAGAGLARGYLNRPALTAERFVADPFSPLVGA
RMYRSGDLARWRDDGNLEFLGRADSQVKIRGFRIEPGEIEALLLALPGVAQAAVIARDDG
LGLQLVAYWVPSALSNASAETLRPALAAQLPDYMLPSAFVALDALPLTPNGKLDRRALPA
PERGGVLFVPPSSQEETLLAALFGEVLGLERVSVDDSFFALGGDSILSIQLVSRARRAGL
EIRPRDIFERPTVAGLASIARPVANNKPLALFEASGPFTPTPIMARFLAVEGPTKGFYQA
MMIQLPAQIEADQLNAILQSTIDHHALLRATFIRNEDGLWQGIVPPPGTVNACTRVQRID
LRAMDSAQRELRLHETVTQAAERLDPADGYLFEALWFSLPEGERLLWIIHHLAVDGVSWR
ILLSDLAAAWQAVAAQQAIALEAVATPFRIWAQRLHEQALSPTVAAELPAWESILARGVP
LLPGIIMDSQRDTTATTQTLLVSLKPALTLALLTEIPAAFHAQINDVLLTALAVAIAAWQ
PATKPGILIDLEGHGREPFADDLDLSRTVGWFTTLYPVALSLEGIDVDAALRGEADMGLA
LKLVKEQLRAIPGRGLGFGLLRYLEPSAGQRLASQPSPQLAFNYLGRFAAGDSQDWAIAA
DGNGLSGGADADMPITHALTVNAVTVDGPEGPTLSAHWSWATRHLDESAVATLAEHWQQA
LSALVAHSMQAGAGGHSPADFPLLTLSQKQVDELERRYPNLETLWPLSPLQEGLLFHALF
DDASPDLYTVQTAIDLSGNLEPERLRNACTALLKRHAVLRTGFVHQGQTPLQVVVPQPPL
PWQWLDLSDLEAVQQSQRAQAVAAELRTTRFAIDEPPLIRFTVLKLGQQQHRLLVTNHHL
VLDGWSMPILLRELFTLYNDFGSKNTLAPVSGYGDYLAWLQAQHKPQAHAAWQAYLAGLD
APSLIAPDRSSQATIQAPHHWRYSFPEALSQGMNDFARNHGITLNTLFQGAWALLLSRLT
GQRDVTFGITVSGRPAELPGVEHMVGLLINTLPLRISLPSDQPLAAWLGALQARQAGLLD
YGYLGLTEIQRIAGGFNPLFDTLLVFENYPIDRAAIKQGISDLKVTHIAGHDATHYPLSL
MVAPGEQLELRLEFDPALFDDEKGQQLGQRLVRLIEQAVAQPDAPLYRYDMLTPEERHTL
LEGFNATAQPIPAATLPELFEMQAARDPAATALIFAGQELSYGELNSRANRLAHALIAQG
AGPEALIGLCLERSFELVISLLAVLKSGAAYVPLDPEYPKARLQAMLEDAAPLLVITSTE
MAAILPESCARLLLDDPSVQTGLAINPESNPSNADRLTPLSPLHPAYVIFTSGSTGRPKG
VIMSQQALVNLLEWQTESSVLGSKLRTLQFTSANFDVSFQEIFGAWKTGSTLVLVPDEVR
REPEQLVDLLRSHAIERLFIPIAALNNIAELYANRTLSPLQLKEVICAGEQLKVTPALRR
FFDRIDHSQLHNHYGPSESHVVTAFPLDQDSRHWQEMPSIGAPIRNTRIYLLDQTLEPVP
VGVAGELYIAGAGLARGYLNRPALTAERFVADPFSPVVGARMYRSGDLARWRDDGNLEFL
GRADSQVKIRGFRIEPGEIEALLLALPGVAQAAVVARDDGLGLQLVAYWVPSVSSDASAE
TLRPALAAQLPDYMLPSAFVALDALPLTPNGKLDRRALPAPERGGAVFVPPSSPEEALLA
ALFGEVLGLERVSIADSFFALGGHSLLATRLVSRVREAFALELPIRALFEAPTVEQLAGR
LRDLRGARLPLQALPRPERLPLSYAQQRLWFIHRLEGPGSNYNIPIALRLSGHLDADAFD
SALLDLLARHEALRTRFPEFDGVAAQEIVPVAEFGSLLTRCQVTEAELAVQLQQAADTAL
DITVDLPFRAWLFSLANEAQVLLMLVHHIAADGASMAVLADDLTLAYSSRCMQQTPRWTD
LPIQYADYALWQRQSLGAVHDPKSPMAQQLAFWQQALRGLPDELNLPADRPRPLVGSYRG
GALPIHLSAELHRNLLALAQTEQASLFMLLQATLAALLSRLGAGEDIAIGAPIAGRTDQA
IEGLIGFFVNALVLRTDLSGRPSLRTVLQRVRAFDLDAYAHQDLPFELLVDALQPTRSMA
RHPLFQVMLALQNTARPRMDLPGLSVAMEPLARTGAKFDLLVSLAEQYDADGEPLGLWGE
LEFSSDLFDTSTIELLIQRWLRLIEQAVAEPDAPLYRCALVTPEERHALLEGFNATTRPI
PDATLPALFEAQAARDPAATALVFADRELSYGELNAQANRLAHHLQTLGVGPNTLVGICV
ERSFEMLVGVLAILKAGGAYMPLDPEYPQERLHFMLDDAAVSVLLTQQRLLAALPSNNAY
VLCLDRDLPLFADGNRSTPPSRAQADDLAYLIYTSGSTGQPKGVAVTHRNVVRLVRSDDS
LSFDSDEVFLQLAPLAFDASTLELWAALLNGGRLVLMPPGQSTLEDIGRHLTRHRVTTLW
LTAGLFHLMVDERLEDLTGVRRLFAGGEALSVPHVQKAAAALGANRIINGYGPTENTTFT
SCYPVPAADAITTSVPIGKPIANTRTYILDEALQPVPVGVTGELYTGGLGLARAYLNRPA
LTAERFVADPFSEAPGSRMYRTGDLARWREDGNLEFIGRADGQVKIRGFRIEPGEIESAL
LGLPQVMQTAVVARDDGLGLQLVAYWVPSEGSDTSAEALRLALSEQLPDYMLPSAFVALA
ALPLTANGKLDRRALPAPERGGYAFVSPSSPEEAPLAALFGEVLGLDQVSVADSFFALGG
HSLLATRLVSRVREVMKVELPIRALFEAPTVAQLARRLRDLRSARLPLKALPRPERLPLS
YAQQRLWFIHRMEGPSATYNIPIALRLTGPLNADALERALLDLLTRHEALRTRFPEFEGV
AAQQIVPVADIDSLLTRCELSEAELSARLQQAADTALDISVELPFRAWLFCLGNEEQVLL
ILVHHIAADGSSMAALSDDLTLAYNARCLNQAPAWPNLPLQYADYALWQRQALGSVNDPL
SSMAQQLAFWKRALRGLPDELSLPTDRPRPLVSSYCGGALPIHLSAELHRDLLALAQAEQ
ASLFMLLQATLAALLSRLGAGEDIPIGAPIAGRTDKAIEGLIGFFVNTLVLRTDLSGRPS
LRTVLQRVRTFDLDAYGHQDLPFELLVDALQPTRSMARHPLFQVMLVLQNTVNARLDLPG
INAAVEPLVRTSAKFDLSANLAELYGDNGEPLGVSGELEFSSDLFDAETVERLSRRWLSL
IEQAVAQPDAPLHQCDILLPEERCMLLNNQTYVLDNALQPVPVGVVGELYTSDIGYARAY
LTNPVLCAERYVADPFSAVPGLRMYRTGDLVRWCKDGNLEFIGHADKPVKSPGFMPIEAA
EPKNDFIPSQTPTESALAEIWSEVLHLQQIDRRDNFFELGGHSLLATQVVSRIQRNLGIV
MPFRALFENPSLGALAGYLDRQCQTETNDSMPLGVAPPILPVSRDQPLPLSFAQQRLWFI
DQIGSGAAYNMSSALRLRGQLNVSALEQSLSEVVRRHESLRTTFDNSAEQPYQHIRAPQP
VALPVTDLSHLPDALRRQETRREAQQEAQKLFDLSRDLMLRTRLLRLDEDEHVLLLSLHH
IAADGWSNDVLMRELAELYEAFATDKPSALTELPVQYADFAVWQRQWLQGEVLQQQAAFW
KKQLQGAPALLVLPTDRPRPPVESFRGGVYPVQLDAKRTAGLRKLSRDADTTLFTTLLAA
FQVLLARYSGQDDIVVGSPIANRNCLETEPLIGFFVNTLALRADLSGNPSFSRVLAQVKH
TTLLAQDHQDLPFERLVEELQVERNLSYNPVVQIVFALQAAKTTGFALPGLEVSSFEFAE
PSVRMDLELHLWEQAEDIIGGCSYAADLFDETTIARLMAHFYTLLDGIIADPERPIHGLA
LLGESESRQILVDWNRTAADLPKNLCLHQLFEQQAARTPDQAAIVFAGQSLSYRQLDQRA
NQLAHHLQSLGVVPDSLVGICVERSADMVVGILAIHKAGGAYLPLDPAYPQERLAYMLED
AAAPVLLTQAALLDRLPAHNAKPVYLDSDWPVIDALPTDQPSNTVTADNLAYIIYTSGST
GNPKGVLVEHRGVCSIIQAQIALLEIGTHDRILQFASLSFDAAASEIMMALGSGAALYLG
TRETLAPGEPLRRFLTDNAISLATVTPSTLAALPEDSLPALRTLGVAGEACSAELFGQWA
KNRRFFNLYGPTEASICATAWRCETITANAPSIGRPLANVLVYILDALQQPAPIGVAGEL
YIGGVGVARGYLNRPELTEEKFIANPFGAGRLYKTGDLTRWLPDGNIEYLGRIDQQVKIR
GFRIEPGEIESVLTQHPAVREAVVLARSDQFGKPRLVAYLLTDGQESPTGALREWLQGKL
PDYMVPAAFVRLETWPLTPNGKLDRQGLPEPDMQANDSEYLAPLTLTESALAEVWRKVLN
VERVGRQDNFFELGGHSLLLTQLIYHIEAALGVLPSMRDLFSFPTLSAQAAHLDACMQAQ
GQDGEPIQSVDFAAESQLDPAIWPPTADFARTAEDLHAVLITGASGFLGAYLLDELARQT
SAELYCLVRADNAEHGVQRLRLNLERHGLWRDELALRLHPVVGDLEQPRLGLAEDEFDSL
AERIDAIYHSGAHDNFLYPYAMLKAANVDGTHELLRLAALVRTKPLHFVSTLSVVSPMVE
QVRETDPLAYPEQAGMGYVDTKWVAEQLVQRAAERGMPVTIHRPTHILGVSDRGYTHIDD
AWYRRLLNDIQLGTATGDDNADDNLVPVGFVSRAIVHLSLQQASLGKVFHLSNPSYTPRS
IYQDVLRERGYSITLLPFGQWLAQLVEAAKTRPDLGLIPLLPMLTAYDTENPAPSVSRHI
HYVNTTAGLADSGIVCPEIRHAELRAYFAYLIDEGHFPPPQRPTIKSSD
>G0PRM4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MANEEQLRSYLRFVTSDLHETRERLERLEAEQHAPIAIVGMSCRFPGDVRSPEDLWDFVA
AGGDAIAGFPKDRGWDLDTLFATDADGAGTSSTAAGGFVYDAGEFDAGFFGISPREALAM
DPQQRLVLECSWEAIERAGIDVSTLRNSSTGVFLGASAQNYGTFADQGGEGSEGYFLTGN
AASVVSGRLAYVFGLEGPAVTVDTACSSSLVALHLAAQALRAGECGLAVAGGVAVMSTPG
AFVEFSRQRGLAPDGRCKPFAAGADGTGWGEGAGVLLLERLSDAVANGHQVLAVLRGSAV
NQDGASNGLTAPNGPSQQRVIRQALSNAGLGTGEVDVVEAHGTGTKLGDPIEAQALLATY
GQDRPEGRPLWLGSVKSNIGHTQSAAGVAGVIKMVMAMRHGLLPETLHVDEPSPHVDWSA
GEVRLLTEAVPWPADGRQRRAGVSSFGVSGTNAHVILEEAPAVEPGSEPTVVVSGPVPWL
VSARGDAGLRGQAARLAEFVRGREDVDVAGVAATLAGRVALQDRAVVVVGEGVADLVARL
DVLAGGGLVDGVVCGSPVGGKSAVLFTGQGSQFAGMGVELYGRFGVFAGVVDEVCAVADG
LLPEPLRPVLFGEGGRGGLIDRTVFAQVGLVALEVGLWRVLVECGVRADVLVGHSVGEVS
AAVASGVLSLADAVRLVCVRGRLMEEVPAGGVMVSVAAPEEVVRGRVVGVAGVWVAAVNA
PGSVVLAGEEGAVRGVVDGLVAEGVRTRWLPVGHAFHTPLMDPVLEEFSREIAGLAFEAP
RIPVVSTVTGEVAGADFGSAAYWVEHARRPVRFADAVGVARGLGVRVWAEVGPQPALSAA
LDVREGEVVASFLRRDRDQATTLLTGLSRLHVHGVDVAWDQWVSRTGPLVEVPTYAFQRR
RYWVAGSVGTAGGSLTEAGLVAAGHRLLGAQVSLAGGGVVFTGRLSVSAQPWLADHAVSG
VVVLPGTAFVDLVVHAGLQVGCGRVDELTLQAPLVLSGDGAGVTVQVVVGEPGEGGRRVV
DVHSRPVDGGGGWTRHGSGVLAGEVGAGGAAGGVGWSWPPAGDVVEGEGVYAGLVDAGFD
YGPVFRGLRRVWVGGEDVWAEVVLPDEPSGFTLHPALLDGVLHALGVMSGGGEGGLPFAF
TGVTVHRAGARVLHARLRRGTEGVRVEAVDPAGRPVVTVESLAFRPINQESLAGSPSSAA
RLLRMRWAPVPGLTADSVGDPAPEWVLVGGDAGDHADLASLNQALESGVAAPSMVVLSCP
GASGASGALGADGGTDAGYEEPEADRAEAILVRLLTEVQAFLASPHLADARLLVLTRGAV
TTEAPAATVDPAMSAIWGMIRSAQTEHPDRFVLLDLDPRDTRAQDDILRALPPAAFLTAG
LDQLATRDGEVVAPALAELDDTDRLRLPANGPWQLSTGSGGTLTELATIAHPRAAETLPP
GTVRLSMRANGLNFRDVLIALGMYPGEATLGSEGSGVVTEIGPDVTGLTVGDRVMGLIPE
SFGDVVVADARTVAPIPEEWSFAEAASVPVAFLTARYALGDLAGLCAGERVLVHAGAGGV
GMAAVQLARHLGAEVFATAHPSKWGALRELGVAEDHVASSRDLGFRAAFLEVTGGAGVDV
VLNSLAGEFVDASLELLPRGGRFIEMGKTDVREAASLPSGVRYRTFDLTEPEPTRIGDML
SELLTLFAEGELKLLPLTAWDIRRAPAAFRHLSQARHVGKNVLTLPVPVDPEGTVLVTGG
TGVLGGLVAEWLVSVCGVRHVVLVGRRGGSEGVAGLVGRLAGLGARVRVVGVDVSSRAGV
VEALGAVEVGHPLVGVVHAAGVVDDGVVGSLSPEQVGSVMGGKAGGAWWLHRLTEGLDLS
FFLVFSSLAGVVGSPGQANYAAANGFLDGLMQWRRARGLVGQSVAWGLWDVTSGMTGELT
RSDVARMSRGGVTGLSAAEGTALLGAAREMPDALMMAARWDWQAWDSAATVPQLLRGLVR
DGSPRNHRGRGPATVDARRRLNRLSRSEALSAVSDEIRGEVASVLGFGSVVDVPVGLAFR
EMGFDSLTAVELRNRLGVLFGVRLSATVVFDYPSVGALAEFVCGLVRVEGGVGRGVSGGV
SGGVPVVDAGDPVVIVGVGCRYPGGVVSGEGLWGLVASGGDAVGGFPVDRGWDLGVLEGV
GDVVPRGGGFVHGAGLFDAGFFGISPREALAMDPQQRLLLEVVWEALEDAGVDAGGLRGS
RTGVFAGVIPQDYVSRLSSVPDESAGYVGIGNTTSVVSGRVAYSFGFEGPAVTVDTACSS
SLVSLHLAAQALRSGECSLALAGGVTVMSSPATFVEFGRQRGLAGDGRCKAFAGAADGTG
WGEGAGVVVLERLSDARRLGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIQQALASA
GLSSVDVDVVEAHGTGTKLGDPIEAQALLAAYGQGRAEGRPLWLGSVKSNIGHTQAAAGV
AGVIKMVMAMRHGLLPETLHVDEPSPHVDWSAGEVRLLTEPVAWPGEGRPRRAGVSSFGV
SGTNAHVILEEPPAAEPKPVAEGEAPVPVGVDLLPWVVSGRDVAGLRAQAAQLAGFVRAQ
RAAGAVGGLWPAGVAAGLAGRAGLEQRAVVTGADVEALLSGLDAVGAGELAEGVTTGPAT
PGSGVVFVFPGQGGQWVGMGRELLDSWPVFADRLAVCERALDPFVDWSLREVLTGSDEKW
LGRVDVVQPVLWAVMVSLAEVWRAAGVEPDAVVGHSQGEIAAAVVAGRLSVEDGARVVAL
RSRALLRLSGQGAMASVALDAVEVEGVLPGSVTVAAVNAPGQVVVSGPPDEVAELCVRLD
GQGVRARRIEVDYASHHAQVEAIEEELRAGLEGLSSRGSEVTMWSTVTGEPVGDEELDAS
YWYRNLREPVRFDAAVRAAQAHRHAHFIELSPHPVLALALSTVLADGSDDGYGRVLHSLR
RGQAERAQLLRSLGEAWAAGLPVGWRGLLPVVEPVALPTYAFQRERYWLDAPPPVAAVGA
AGSGVDGWRYRVGWTPLAVQHAGGLPRKWLLLCQDMADAGEARQALEQAGAQVEVRALPD
DHDIDRAGIVQLLAGAEHIAYLPARVDGGRKAETEPAPGIGTGTGTETGTGADTETGAGA
GVPSGLSAQLAVPLMVMQAVVEVEGARLWVVTRGAVSVSGGGSVPDPVLAAVWGLGRVFG
LEHAGHYGGLVDVPVVWGAGTGGLLVTALAQSVEDQLAVGADGVFVRRLRRAPASLSGRG
VGWRPGGTVLVTGGTGGLGSHLARWLARSGAEHVVLVSRSGRRAEGAVALAEELAAAGTP
TTVRACDITDATQLAEVLGCTDHPPITTVIHAAATIELAHLRDATPEHLSTVLDAKCTGA
AHLADLLGAHHPDVRLVLFSSIAGIWGSGVHGAYAAANAYLDALAESRAATQPITSVAWG
IWDTELALGRVDPDQMYRQGLPFLDRDRALDALAQVLAEEETVLAIAEVDWPTFVPVFTA
ARPRPLLSELPDVRALESAEQESTAPTASSSALVERLATATEAERDAALLDMVRTEAASV
LGHTGLDDIGPHRALRDVGFDSLTAVDLRNRLGAKLGVRLPATVVFDYPSPQALAAFLKA
EVWGGAPVTDSTPRPVAFDSEPLAIVGMSCRLPGGVHSAEDLWNLLSEQRETVSGFPADR
GWDAGSLHRPDREGSNGVSARGGGFLHDAAFFDPEFFGISPREARAMDPQQRLLLETAWE
AFEHAGIDPESLAGTPTGVFVGSNYQDYGANLAAVPDGTEGHLLTGGASSVLSGRIAYTF
GLEGPAVTVDTACSSSLVGVHLATQALRLGECSLALAGGVAVMGSPGALLAFSKQGALSP
DGRCRSFSAEADGMGMAEGVGLLLLERLSDAVANGHQVLAVVRGSAVNQDGASNGLTAPN
GPSQQRVIRQALANAQVDAGEVDAVEAHGTGTTLGDPIEAQALLATYGKDRPEGRPLWLG
SVKSNIGHTQAASGVTGVIKMVMALRHHALPATLHADTPSPHVDWATGDVRLLTEPVPWL
ADGRPRRAGVSSFGVSGTNVHLILEEAPAAQAPTAEGPTTGAPEEEEAPRTAALLDAGPV
PWVVSGRGDAGLRGQAARLASFVRAAQQAAGEVDREWIAGVASGLAGRSALEQRAVVLGA
NVHELLADLDALAETGRPSPRRTTDPGVVFVFPGQGGQWIGMGRELLPACPVFADRLAEC
ERALDPFVDWSLREVLSGGEREWLGRVDVVQPVLWAVMVSLAEVWRAAGVEPDAVVGHSQ
GEIAAAVVAGRLSVEDGARVVALRSRALLGLSGQGAMASVALDVAEVEGVLPGSVTVAAV
NAPGQVVVSGPPDEVAELCVRLDGQGVRARRIEVDYASHHAQVEAIEEELRAGLEGLSSR
GSEVMMWSTVTGEPVRDEELDASYWYRNLREPVRFETAVRAAHDHGRGVFVEVGPHPVLG
LALSTVLGEGESDGEGRVLHTLRRDQSETAQLLTSLGEAWAAGLPVAWRDLLPAAEPVAL
PTYAFQRQRYWLDAPAIAVDAAQPVGASPSDAWRYRVGWTPLAAQQADRLHRRWLLLCHE
EADAHEVQQALEQAGAKVDVRVLPAAADAAPEIDRAGVAELLRGAEHIAYLPAGLDRSHP
DHPGLPVGLAALLTVVQAVVEQEGARLWVLTRGAVNAPGTGGAPDPAAAAVWGLGRVFGL
EHPDHYGGLIDLPALWQPRTGGQLAAALAEPVEDQIALRADGTFARRLQHAPAPPRGDQE
WKPRGTALITGGTGALGAHLARWLARNGAERILLVSRTGPDAPGADDLARELTDQGTPTT
VVACDIADPQQVAALFDGGDGHPPVTTVIHAAGVPQRTTLQESDPAAFAELLRAKVTGTH
HLLAALDEHPADELVLFSSNSGVWGSGLHGAYAAANAYLDAVAEQQREQGRRAISVAWGL
WGGGGMAEGDGEEYLSRVGIRPMAPDLAVAALHEALTLDETFVAVADVDWERFVPTYTVA
RRRPLIEDLPEVRRLAGARDTATADAPDDEAQSLRGRLAGLNADDQYAELLAIVQREAAK
VLELRDPEAVAEQSAFRELGFDSVMAVEVRNRLRRLSGRQLPATLVFDHPTPGAVVTYLR
GAMFPDGAEAVTSPLAQIERLEKSLLSGDRPDSREKARITLRLQSLLETWRGDGDEQREG
REDSGAQPFESATPDEVFDFIDKELGQR
>A0A1R3U609|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Agrobacterium rosae|TrEMBL
MTYEILGRSCMVPSAGDANQLFELLRQGICAVSTIPDERWSKARFWHPARGMPGKAYTFA
AGILAGVYDFDPAVFGISAREASYMDPQQRILLQAVWRALEDASISQAELQRERVGVYIG
ASSLDNGNLQIEDPASGGPHFMTGNTLSIISNRISHSLGLNGPSMTIDTACSSSLVALHQ
AERALRDDEIDTAIVGGVNLLLHPFSFIGFSQARMLSPEGLCRAYSDNGEGYVRAEGAGA
VVLRRTDRALRDGSRSRATLVASGMNSAGRTNGISLPSREAQAQLLRSVYSDNGIDPGQL
AFIEGHGTGTKVGDPAELWAIGSVLGQVRSQPLLIGSIKSNIGHAEPASGILGLIKAVLS
LENDYLPASLHAELLNQNIDFNDLNVEVNRAGRALERGAERRMVGVNSFGFGGTNVHVVI
SDPPSVAEASVADEAGTFILSAHTQSALHTLLEEYDARFAASSTAQKANIISATRNRSLL
KHRFVTAGNSAEDISSAVSSYFDKGHDTDFQVGEVPGKAVKTAFVYAGNGSQWAGMGIDA
YRESGEFKTRFDHISQLFSARAGIDIAALLFADDLDQQLRDTRIAQPLLFAVQAALTDCL
VSYGVKPDIVFGHSVGEVAAAYAAGILSAEDATTIVSIRSKHQHALAGMGTMAAVVMSEP
SAVAFAQRHGLDNIKVAATNAHNSVTISGPVDEIRGFKAAAQATRNSVHILDINYPFHHP
VIDGERAAFLEEVPLLTPQSGHVTFISTVTGAEIDGEELDANYWWRNVREPIAFETAVNV
ALEAGCNLFLEISPRSILSTYVAETAKKRSASAVVLPTLARPGLANGVDPVKRSALRGIS
HGAKVADTSGRSRGMSGIDLPPLPFENATYRPNMTSDAINVFGRDGADGPYTLLGWRTDP
NASVWKNHIDALLFPDLAGHVVDGKSIMPGSAFIEIAVQAARAYYGTPEVEITNLEIFRP
LELRDNRMAELSTRISPETGVIEIASREYMSDDGWTIHVTARSRRSVGLSRKTELNVVPL
GKPQAISAVQAYETARSFGLDYAPCFQLLERAEVFGDRHIVVNLRRAASPVHPYLSYGMD
PVSTDAAFHGLVALFGTLTGEIDGAPYIPVRFGAVRTASSGQPIVSAVIQIQRFSANSLK
ARIELLAEDGTLVAALDDCRFRRTWLRQHSTLDTVAFHYEAVARQQILSHTPSQAVAALP
ASLFAKATKAQADEATLLLDAAVQRACHDIALLIAGKDQTVFLSSLPGDTEFQCFLSSGL
YTLEDAGIAQFVDTGWTIQPDSGLPPLSDLLNEIYRRFPERVAETVLINNAYRETLKRLA
KGSHSEPDQSSSFLSDATLDHVRHHTALGRRREQLVIDAVNAALMDVFPGDGVTIVEAGA
VSMAFSNRLADVCASKGARLVIVEPSDHLRRTLEIGFERNPSVDCLAPDDVSQLDRADVV
VSASGSLYGHFLQHSGLKDVLRAAASSAGRVAIAETSSSALSDFVFGLTENWFSVSTTAE
FPTGLFASTTQWEDLLKECGFGTPAVEQSDFAEGGLLLVQAATFTKLPQAMSARRLSHRC
SRYRKKKAITLSCLVISQKRCCARPTRRALHSIRCLQNAYPIRSLSYLRFPREALVRSAF
RMLF
>K9U4C9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Chroococcidiopsis thermalis (strain PCC 7203)|TrEMBL
MNSETNGLEIAIIGMSGRFPGSKDIDGFWKNLLDGVELVSSFPDRVSDKSKQSKQKVKVG
AILQDVELFDASFFGFNPREAEIMDPQHRMFLECAWEALENAGYDSERENRAIGIYAGVG
MGYYLYYNLYPHRDLLQSIGGLQSLIGVDKDYVPSRVSYKLNLKGPSISVGTACSSSLVA
VHLACQSLLGGECYMALAAGVAVKVPQNELTLSPDEIISPDGHCRAFDAKANGTLGGNGI
GVVVLKRLEDAIADRDYIYAVIKGSAINNDGSSKIGYTAPSEDGQARVIHAAQVMAEVEP
KTITYMEAHGTGTPLGDPIEVAAMTRAFRLSTDKKGYCAIGSVKTNVGHLDAAAGITSLI
KTTLALHHKLLPPSINFEQPNPQINFEHSPFYVNNKLREWQANGSPRRAGVSSFGIGGTN
AHAILEEALVECNQEERGRKYQLLVLSAKTSSALEAATTNLVRHLKQHPQLNLPDVAYTL
QVGRREFHHRRMTVVENLEDAIATLESATPQRVMTQIQEDDRLVVFMFSGQGSQYVNMAR
ELYESEATFQAECDRCFELLQPHLQLNLAEVLFPTAATAHNAAQQLQQTAIAQPALFVIE
YALAKLWMSWGVRPVAAIGHSIGEYVAACIAGVFSLEDALAVVATRGRLMQQMPPGKMLS
VGLSTEEVQSFLNENLSLAASNAPKLSVISGCELAIEQLERELQARGIDFRHLHTSHAFH
SAMMEAIVEPFTEYLKTIDLKPPQLAFISNVTGTWITTAEATDQNYWARHLRQRVRFSEG
IAELFQDAKRVFLEVGPGRTLSTLAKQQAPGRVVLSSLRHPKEEQSDVAFVLHALGRLWL
TGVQVDWSRFSASEQRRRLPLPTYPFERQRYWIDPPAALPAVQMPPTPLEKENYIPQVTA
QDKRNIADWFYVPKWKPTNISLNKSSDASILGCTLVFADRCGLSVQLLKQLKQQGQNAIA
VQIGSEFAQIDEFTYSLNPQNGNDYNVLLSKLRAQNQLPATIVHLWNVTSQSYAGSELAG
VEQAQYLGFYSLLFLAQAIGKQNVTQKLQIAVVSSNMQPVTQAEIHPEKATLLGAVKVIP
LEYPNITCRSIDLSVGQNEQLVNQLLTELTAPTFEQISAYRDDRRWVQVLEPVRLEETAA
KTPRLRERGVYLITGGLGGVGLVLAEYLAKTVRAKLLLIGRSAFPARADWQTWLATHDES
DRTSYQIRKVQELEALGAQAIVANADVANLEQVQQAIAQAKQQFGQLNGIIHAAGVAGGG
AIGRKTFEAAQRVLAPKVKGTVVLDTLLKDTQLDFFVLCSSLASAQGGFGQVDYCAANAF
LDAFAHYKTTTDGTFTVGINWDVWQEVGMAATAKRSPANSVTKTQSLAVNHPLFDSCIIE
NSQEFYISKLSVSKHWILKEHRLMGKAMVPGTAFLEMALAAWANHTHQQNTRATQMREVY
FPTPLIVEDDVEKEVRTILKQKGDRFEFKIVSYLNSESEQWLEHAIGEITSLDVDSSQKL
AIAELESKCNEGKNVIQNNYHPLKGFAEFGSRWNNLKQVNLGQNRGLALLELSQEFIDDI
GSYKLHPALFDLAVHFLVDEFRGESYYLPFSYKKLTIKGSLPAKIYSYSRLLDRSPSGNL
KFNLTILDDLGTELIEIEDYTLRQFHDTKQHSLSLSK
>D9T6X2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / BCRC 12538 / CBS 129.76 / JCM 10878 / NBRC 16125 / NRRL B-16091 / INA 9442)|TrEMBL
MTVSLDEVVGALRASLLDNQKLKQQNQQLTAALSEPVAIIGMSCRFPGGVRSPEQLWDLV
AAGSDAMSAFPDDRGWNLGALYDPDPDPDSRGTSYVREGGFLYSAGDFDPAFFGISPREA
LAMDPQQRLLLETAWEAFERAGIDPTRLRGAPTGVYAATSSQGDYAALLTGVTGGVEGYL
GTGSAAAVASGRISYALGLEGPAVTVDTACSSSLVALHLACQALRLGECTMALVGGVSVM
ATPTVFVEFSRQRGLSTDGRCKSFAAAADGTGWSEGAGMLLVERLSDARRNGHPVLAVLR
GSAVNQDGASSGLTAPNGPSQRRVIRQALANAGLSADQVDVVEAHGTGTTLGDPIEAQAL
IATYGQGRSADRPLWLGSIKSNIGHTQAAAGVAGVMKMVLAMRHGVLPPTLHVDEPTPHV
DWSAGAVSLLTGTQPWPETGQPRRAGVSAFGISGTNAHVVIEQAVATDTDDVRPAGTPAP
PAPWIVSARSAPALAGQARRLLAHLADHPDLTAADVAYSLVTTRAALPYRAAVIGGDRDA
LRAGLHAVAEERDTPGVVRGVARRAGKVAFLFTGQGAQRPGMGAELCRRFPVFAAAFDEV
AGELNRHLSRPLREVVFAGADSPDADLLDRTEFTQPALFAYEVAAYRLVTAWGLRPQFLL
GHSVGELAAAHVAGVLSLADAATLVAARARLMQQLPPGGAMLAVQASEAEVVPLLDERVS
LAAVNGPRSVVLSGDEEAVLAAGRRLSAEDRRSRRLRVSHAFHSARMDAMLADFRIVAEK
VAWHPPNLPIVSDRTGEPLTAAQATDPGYWVDHVRDTVRFHAGVATLAAGGVGTFVELGP
DGALTVLARECLPDMEPAAFVPLARRDQPETTTLLAALAAVDLRGAGVDWAAPFDGSDAA
RVELPTYAFHRERFWPDPPTVDLVPPAATGEDEEFWAAVAQGRPAELAAALGLPADRQDA
LADLLPALASYRDRRRRGSELDGLRYRADWERVDLSAPTTPAGRCLLVAGAGTDATAVLT
VLRAEGLDPTLVTVGDDLDAVARALLADGTWSVVVSLLAAEERAAGTGTGALAGTAALVR
ALAAAGNGTPMWTVTRGAVAVDAHDAAPGVAGAYVWGLGRVLALEQPRLWGGLVDLPAEP
DDVALAALARVVASGGDEDQVAVRAGGVYARRLHRAPAGATDTDWRPRGAVLVHGSAQVR
TPHLLRWLAERGASHLVLVGPVADADPLGPDVTVTAVDDLDGLPEALDRLAATGSEIRTV
LHVADSDGAGDPVAVLDPHDLADAVAARTTAVELLGRACAGLPIDEFVVFTSTAAVWGSG
GAAVAAAVGAGLEALAAGWRAAGRPATVVAWVPWADEVTDAAQLRRRGVRPLPADVALSA
LGQALVRGDDQLAVADLDWPAFVPAFTAVRPSALLRGVPEATAGAEPEAGDAAATDPARA
LRERLAGVPAGDRHRILLDLVRARVATVLGHASPNAVEADRDFLELGFDSLTALELRDAL
RQETGADLSTTLLFDHPTPTALAVHLIGQLLGAEAAGDGADDAGGSAGNGAGGGLLGGLF
NQPKAREDPAGYAELLVKLAQFRPSFREPAQLTRPAGILRLAEGGARAQLVCCCTMSLLS
GAHEYARLAAGFRGVRDVWALPNPGFGAGEELPADLDALLRVHADTVLRTVGAGPFVLAG
HSGGAMVANLLAGELERQGRPPDAVVLMDTYPADSEVLGGWVPQLLDGMIDRDTAYTPMD
DWRTTAWAGYLPLFLDWQPTETAAATLLVRATEPLGEWDGEPDGWRSRWPYPHEAVDAAG
DHFSMVADRGPELAGTVQRWLVARGL
>A0A1D2I6Y8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. AVP053U2|TrEMBL
MSSEDKLRDYLRRVTAELQVTRRRLREAESRSAEPVALVGMACHYPGGVESPEDLWTLVA
EGRDGITGFPRDRGWDVDGLYHPDPDHPGTSTVRDGGFLHDAPAFDAGFFGISPKEALYT
DPQQRLILQTSWEAVERAGLDPAALRDTRTGVFTGVMHHDYHGAQGGGSVVSGRVAYQLG
LRGPAVTVDTACSSSLVALHQAVRALQRGECDMALVGGVTVMATPSAFVEFSRQRGLAPD
GRCKPFAAAADGTAWSEGVGVLVLERHSAAVAAGRRVHAIVRGIAVNSDGASNGLTAPNG
PAQRRVIQDALVDAGLTPAQVAAVEAHGTGTPLGDPVEAQAVLGVYGGDRPRPLWLGSIK
SNLGHTQAAAGVAGIIKMVLAMRHGVLPRTLHLDRPTPYVDWSAGAVELLAEPVPWPAGD
EPRRAAVSSFGVSGTNAHVILEEPAAATPAPGAEPAESWPGAWAVSGRSPAGLRAQAAAL
AADLAARPDQDPRDVASAFVTTRAAHEHRAVVCAADRDGLLAGFADIAAGRPSPTVVEGV
IGAPGPVAFLFPGQGSQWREMAVRLLESSPVFRDRIAECEAALAPYVDFELTSVLRGEQD
YDRVDVVQPVLFAMMVALAEVWRSVGVTPAAVAGHSQGEIAAAYVAGALTLPDAARVVAL
RSQALVELSGLGGMMSVALPADQVRERLRAWGGRLSLAAVNGTASVVVSGDGDALDELLA
ELEAEEVRARRVDVDYASHSAHVERVQERVRAALAPVVPRPPAVPFFSSVEGRWIDGDDA
FDADYWYRNLREPVRFDEAVTALVGHGCTTLLEVSPHPVVATGAQETVDAIGAEAAVLHT
LRRDEGGPDQLVRALAQLHVQGVRPDWSAVWPGAGPVELPTTAFVTERYWLPAGGGDPSA
LGLDAVEHPVLRAAVPGADRLVLAGRLSAATHPWLADHTVEGHVVLPGAAMVDLVSRAGD
EAGCPVIDQLTLLVPVVVPEDAEVRLRIEAGEPGTDGSRDVTVQGRVGAGNWTLHATAVL
MPGGDPPPPAATAWPPAGAEPLDVDELYARLDSAGLRYGPVFRGVRALWRDRAGDLYAEV
ALPGAEPGGFGVHPALLDACLHPLALGDLRTGAQDRPALPFEWTGVQVHAVGADTVRATL
TGVRDGAVRIELTDPAGTPVASVRSLVLSPLPDGALGLPDRGDLLLPQWAPLPLRDGPAA
GYAVRDPALARLLRVSPSADVAPFILVPAPSGPPAAAAEGALALVQEWLADESRATSTLV
VVTRRLLDDPGEAATAALVRCAQLEHPDRFAVLDLADGDDATVAAVPAALVAGEPQVGLA
AGAARELRLVRVSPAGEPAGDLGTVLVTGASGTLGGIVARHLVHDLGVRDLVLASRRGPQ
APEAATLAAELTAAGAHVAVVACDVADRAELTELLGTTDVGTVVHAAGVLDDGLVGDLTP
ERLARVLRPKVDAAWLLHELLPQARLVLFSSAVDVLGGLGQANYAAANAALDALARVRRA
AGLPGVSLAWGLWADESAMTGGADLARFRRSGFPPLPRDAALAALDAALTVAEPVLVPIR
LDLAALRATGDAVPPVLRALAGAPARRTATRGGAADSELVARLAGKSPADRHRVLLELVL
GHAAAVLGHASPDTIDPDRAFKDAGFGSLSAVQLRNRLSGATGLRLPVTLVFDHPNPAAL
ARHLADRLAGAERPSAAPVTAGTADDPVVVVGIGCRLPGDVRGPDDLWDLLVSERDAIVP
FPDDRGWPLAQLHDPDPDAPGTSYTRSGGFVSGAAEFDAAFFGVSPREAVAMDPQQRLLL
ETVWETCEDAGIDPDTLRGTGTGVFMGAMYQDYGRLLEGAAAEGFLAPGVGGGVLSGRVA
YTFGLQGPTVTVDTACSSSLVALHLAAQAIRAGECDLAFAGGVTVLATPAVFVEFSRQRG
LAADGRCKPFAAAADGTGMGEGVGVVLVERLSRAREHGHRVLAVLRGSAVNSDGASNGLT
APNGPAQERVIRAALTAAGLGPADVDAVEAHGTGTVLGDPIEAQAVLAVYGGDRPRPLWL
GSVKSNLGHTQAAAGVAGVIKAVLSLRHGVLPRSLHIDEPSSHVDWTAGEVALLASAQPW
PRHEAPRRMGVSSFGISGTNAHVVIEEAPPAPDAEEERPVLDGVPWLLSARSEAALRAQA
ARLAATAATDPSAVAYALATTRAVHKHRAAVTGADETALRTGLAALADGNTVPSVLRATA
ARHRLVLVLTGQGSQLPGMGRGLYETFPEYARAFDEVSAHFTLDTPLQEVVWGDGSLLDR
TEYTQPALFALQVAQFRLVSAWGLRPEMLIGHSIGELSAAYLAGMLTLDDAATLVTARGR
AMAGLPAGGAMVSVGAAESVVLPLLAEHADRVSIAAVNGPDAVVLSGDEDAVLELAGVLS
ERGHRTRRLRVGTAFHSARVEPALDAFRAVAEAVTFQQPRIPIVSTVRTDEKMISPAYWV
DQLRGSVRFLDAVQEADRAGGTAFLELGPDAVLAPAVRACLPAAPVPPVALARRDRPDAR
AALGALGALHTYGVRVDWPAVYAGHEPRRCPLPRYAFQGRRYWPEPAPAAPAPAPAMAPA
PASDALWSALDSGGPAAALGMLGLRGDETPHQVLSAVARLRPGAGTARRPVRWRPVPDGV
PPVLDVTVALVSPPGDDQDLTDALAGALARHGARVTVDAAERPDLVIVLPGAEPAGTPGV
PSWVLTRDGSLPASGHVVDLPPEMDARARTRLCTVIGQGYTAARIRPEGVFVAEYGDEAS
PAPPAPPPPPAPGSGPSGGLRAALARLPRDRWDAEVLTGVRELAAAVLGHDSGAEIGTGD
EFFDLGLSSVTALELRDHLGTLTGLEWAADVLYECPTPQALADLVVARMSEGE
>A0A0N1GYL8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OV450|TrEMBL
MVLDTQLALLAESGLGEGAAAVLRALDGSETIVVDGHRVLLRPGAEMAAPQPPDVQQAGG
ASGSQVLSGRGGTVSLPVGQDGFLAARFAAWWGTAGQAVRAMREALEHTVRLSVSQTALG
SEAAMSRTLGTRLPIAQGPMTRVSDQAGFASAVAGEGALPFVALSLARQEQGRAILEAVD
AALAGRAWGVGLLGFAPEAIRQAQTEAVLGIKPSHVIIAGGSPSQARAFEEAGIAAFLHV
PSPGLLSQFLKAGARRFVFEGSECGGHVGPRYSFPLWEAQIAVLEDYLDASDDEGLASHI
EVFFAGGIHDECSSAMVAALSAPLAARGVALGVLMGTAYLFTEEAVTSGALQRTFQRKVV
AAQSTMLLETAPGHATRCVPSHFSRSYETAKAGLVGKGITGRQLWEDLERLNVGRLRIAS
KGLQRQGEELVEVNAGRQLAEGLYMAGDVAVLRSAPTTIAALHRAVTSSAASFFTDQVTA
LGERLGIRPEKDSSQEQEAPVPLDIAVVGMACMFPQAPDLASFWANTVHGVDAIEEVPAE
RWDSKLHYRYDGKAAKTGMSASKWGGFLPRIEFDAVGYGIPPASLPSIEPVQLLALEAAR
RAMDDAGYGESARAFDRSRTAVVFGAEAGSDQASATLLGTMLRSAYGEIPEELADQLPTL
TEDSFPGMLANVISGRIANRLDLGGANYTVDAACASSLAAVDVACKELTSGTSDLVLCGG
ADLHNGINDYVLFSSVHALSPTGRSRAFDSAADGIALGEGVACLVLKRLADAERDGDRVY
SVIKGIGASSDGRSLGLTAPRPQGQRAALQRAYLNAGISPAAVGLLEAHGTGTVVGDRTE
LSTLTDVFTEAGAATGSCTLGSVKSQIGHTKCAAGLAGLIKASMSLYTGVKPPTLNLQQP
NPAWQADSSPFVFHTKATPWAAPPAERVAGISAFGFGGTNFHTVLTAHGKTPPPPHGLQQ
WPAELFIFRGTTQASAHQAIKDVLALHSEAKSGKQLWRLRDLARAASRLAETSRGPVWVA
VVATSLTSLGEQLRRALAGEHDPATGIYVPPACAPQRGDEDAPAGKTALLFPGQGSQRPR
MFAEQFIAFPELQDLLQSDRVCADLLYPPAGFDAATREAQCTSVTDTRIAQPALGIAGLA
AYTVLTQAGVTGDMTAGHSYGELTALCAAGVISPRSLLKLSAQRAESITKAIGDDPGAMA
AISARHDEVKERLREAIAGGRVVIANHNAPEQSVISGLSEAVDAAVDMLRSAGYSARRLP
VACAFHSPVVEGATTRFAHALKSHSLRAPEIPIFSTRTAAPYPTAPDEIATELSAQISAP
VRFAEQIEAMYAAGARVFVEAGPGSVLTQLVGAILGDRPHYAVACEPRPNAGLPGFLTAL
AQLAVAGVPVRTGWMFRGRDALDAGQGSTPKQGGWTIDGQGVRTADGELLTPSVRPVIRK
EHLVPDTRHNDQPSDREALIHAYLRASREMVAAHREVFLSYLGAPHAPYADPAPVPPVAA
GGYLPGRLHNSEPPAAESISAAQEADEVLLAVPTEAELIRTVTEIISTRTGYPLDMIEPN
LDLEADLSIDSIKRAEIVGELASQLALPAGASPSLSAEELEELAGAHSTTAIVGWIMARL
TASAHSTSPASPPASSAADPNTAEPSSVTAPRVPQPATRTQPAEAASAPPRRFQVVRAAL
PDASMPEERSSALAGKRFVILGDGDGAALATAAALARLGAETQTRRGSHLLTEQDGPIDG
VLYLQPLSQAVTGLLPQAFSVIKCALERAPRWLLAARCGDAPVPRAAGALGTAGLRGLFR
TISKEHPEMVTKVVEVDGATSQSPAAIAEALVSELFTQEPAVVLRGSTGRYGLELRESPL
SSLSAKGAGPAGTGAAEAAAIELTSQSVILLTGGARGITAQCAAALAAASRCRIELIGRT
PLPHTPEDPATSAARDRLALRAVLATQGADRTTADIDQAATRILAQREILATLDKLRMLG
SPARYRCVDVCDDTAVFEAVNDIYAHYGRLDGIVHAAGVIEDRLMADKTPRSFHRVFATK
AGGAAAVLKAAGELPIPPRFVVCFGSISAVVGNRGQGDYSAANDAQEELATQWAAATGRR
ALTVHWGPWAPSGDHTGMVTPELAGEYERRGIQLIDPEEGVGSLLRELAWGDPSHTAVVY
TASGW
>A0A8B4DUN2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus subsp. abscessus|TrEMBL
MDSAENPIESTPRFAIIGYAARFPGAADAEEFWDVLREGRDAISEVPADRWDAEEFFDPE
PGAPGKVVTRRAGFVEDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGIAPTD
LAETNSGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQGPSVAV
DTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSHAHMLAPDGKCKTFDA
AADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
DALKRAGVAPSEVGYLEAHGTGTSLGDPIEAQAAGAAYGIGRETNDPLLIGSAKTNIGHL
EAAAGIAGVIKVILSLENELLPQHRNFQNPSPHIPWDRLPVEVVREARPWGRNGRPRIAG
VSSFGFAGTNAHVILEEAPVVSRDAVEPPAPAGGRKFSILPLSARTPAALAQLADKYRAW
LNAHPEAALADLCFTAGVGRAHLEHRAALVVNTREAAVELLSAVADDRPAPGLGRGESHD
TPKTAWLFTGQGSQYPGMARELFETEPVFADTLNRCAAAVADVLEKPLLDVIFDVDGPEA
EETLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAEVFSLEDGARL
IAERGRLFGSLPAGGRMAAVFTDAERVERLTDEFPSLSVAAYNGANTVLSGPAQDLEKAI
AALVADGVRCDFLETSHAFHSALLDPILDEFEAYANQFNYKTPQRILIDNRTGTALGRSV
KLDGAYWRRHARQPVEFAKSVRTLADMNCKVLLEIGPQPVLTAAALRAWPDPATAPRAIA
SLRRNTADHRQITEAAADAYVLGHLPDFGAFQHAPARKLDLPTYPFERRQYWFSDKRDGD
NRDAGNRQQNNGGPRTEAVRLLEDGKIEELANLLGGVDGDQQTLNVLTKLAAQHNLQRTT
QTIADDRYQFRWEKSPTPLSGSQAAGGVTWLLVADAAGAAQPLLDVLTARGQQHRVLALP
VSDADEAELVEALRSAADEDSALRIVHVAALAGQGSSSTQSLLRIQHQVLGGTRRLFRAA
AAAELRAPIWIVTRGAQHVIEGDTVAPEQSALWGFGRAAALELPQVWGGLADLSDAGTDE
WAQFIGRVSVSGEASTREDQLALRGQAVHVPRLVRREELPSGKPLEVRSDATYLVTGGLG
SIGLEIAGYLAGRGAKHLVLTSRREPGEAARQRIDALAAQGCEVRAVTADVADGHDVARL
LAGIQAELPPLAGIVHAAGEIGTTPLSDLEDAEVDRVFAGKVWGAWHLSEAAAGLKLDFF
INTSSIAAVWGGYGQTAYSAANAFLDGLAWRLREQGIAGTSVNFGPWSAGMADAESRARL
EQRGIKTLSPTDALAGLADVVAASGSNAVQGVIARIDWARFLPLYQQAGKRGFLAELDRE
VPSHLAGVAGAQSGSTQLVERLANAPVQQRKKLLTDYLRDAVAEVTRVDVSEIREDAGFF
DLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLGDVLGLAEQAKPAAQLA
SAVTDRTDEPIAIVAVSCRFPGAPDPEAFWDVLSGGVDAIREVPEDRFDIDEFYDPDPEV
AGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYSPAALRG
SRTGIFAGVGANEYAHLLSSESIDKIEPYFITGNALNAISGRVAFALGFEGPAVAVDTAC
SSALVAVHQAVQALHSGDCDLALAGGVNVLLSPVTVIAASRARMLSPVGRCKTFDASADG
YVRSEGCGILVLKRLSDAERDGDRVLAVIPGSAVNQDGASSGLTVPNGGAQQRLIGSVLA
RAGLVGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGGSRDADRPLLMGSVKSNIGHTESAS
GAAGLIKVVLSLQNGVLPQSLHFDNPSPHIPWESLPVRVVDKAIPWQANGRPRRAGVSSF
GFTGTNAHVLIEEAPQPQATPDEDDASTPQSAPVSVLPLSARSPEALAAVAQRYESWLAA
HPDVDLEDVCLTAGRGRSHFEHRAALVVDSIQTAREGLLELAQNRLRPGVVRGEHTNHPT
TAWLFTGQGSQYPGMARELFDAEPVFAETVTRCAEAVKDIVTRPLLEVMFATDRETGGKA
GEALRHTSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSIEDGARL
IAERGRLFGGLPAGGRMVAVFSDAKHVEQIAGEFPRVSVGAYNGPNTVLSGPGEDLEQAV
ARFQEEGIRCTWLETSHAFHSELLDPILDEFESYAAQVQFAAPTLPLVCNRTGAVLTAQT
PIDGQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAPPRAIV
SLRKGVEDRRQIADALASAYVSGHRPNFAALQRHPRRTVELPTYPFQRRRFWPKSSGTAI
EGGGGLPSGILGRGEDLASGDSVYISRLSVRSQPWLSDHVIYGTVVVPGATYAAMALAAV
GTPARAKDVFFYEPIILPEKSSREVQLTLHPLEDGSGSKFQVHSRPYGERDVDWSLNAEG
TVVTGIGDDAEPAPEAAEPAEPVDAAIERMERMRPMELFEIFADLELAWGPTWSGSLKSL
WLGEGEAIGDVLVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLR
YGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYLDRDGRHLGGIREFTVKRAPREAL
LRGLGGDATRLLYTLGWHEVAVPPVADEGEESAASIGTWLIAGFDELAAKVPGCIPLNRE
TDPELLGEVLVAAKERGVPFSGVVWRAAGPGATESTTESAARLEGEIAHLLSAVHTVQNS
AQNGVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTINEEPALRAKLVDGDGSPE
AVQALARLLVTPVEEPEIAVRQGKLLASRLLPWSRTGHLTVPRGSDYVLAPTERGAIDNL
RITEKEVPAPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGIVTQLGEGVTG
VEVGQRVYGSMQGAFGSRFNVPAQFLAPIPDGISGVEAATIPAAALTVRLSFDWAQLKPG
DKVLIHAASGGVGLAAIQMAQQFGAEVFATASTFKRATLRKLGVKYVYDSRTTDFADQIL
ADTDGAGVDVVLNSLTSEGFIEATLRATAKNGRFAEIAKRDIWTTEQMAQARPDIAYEIV
ALDTVMFQEPDRIRVLLTEVSEGLAKGEWTPLPAEIYPLTEARTAFRRMQQARHIGKIVC
QMPNPLAPRPDRTYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRAPDTDAQRLIGEITE
RSKTRIHVFTADVGAESEVAGLLERIRAELPPLAGVAHLAGVLDDALLGQQSVERFRTTL
APKAFGAEYLDRLTKGDDLDFFIVSSSVSSLFGSPGQSNYATANALLDGLIAQRRAQGLP
ATGINFGPWGQGGMASSEAATANISAQGLIPLDPSAALAALAEVIANGTGQATILKANWQ
RAAKVLGSSRPPILDLVLPSAVGEVTGDSELLKQLMEIPVPQRAGFVTEFLQREVQNFLR
LAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL
PDADAESVEAPPAVESAEAESGTGPAAASDAVSELKE
>A0A0N1GUD6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OV450|TrEMBL
RRRARRNGHEVLAVIKGSAVNQDGASSSMTAPNGPSQQRVIRSALENAGLTIADVDAVEA
HGTGTTLGDPIEAQAVLATYGRRPAGDKPLYLGSLKSNLAHTQAAAGVGGVIKMVQALRH
GLLPKVLHLDEPTPHVDWESGNVQLLTEAVDWPAGERPRRAGVSSFGLSGTNVHVILEEA
PAAEPAEQQSGARELPLVPVVLSGRSARALTDQAAQLHARVAADEALTLTDLGYSTATTR
TPHEHRAVVVGADREELLSGLSALAEGAIADAGVVEGQVRDGRTAFLFTGQGAQRLGMGR
ELHAAFPVFARAFDEVVAAVDTYLDTPLYEVMWGADEALLNSTAYTQPALFAIETALFRL
VESWGVRPDFLAGHSIGEITAAHVAGVLSLEDAARLVTARGRLMQALPAGGAMAAIEATE
EEVLPYVGDVVGIAAINSPRSIVVSGAEAAVEAITEEFGGQGRKTTRLRVSHAFHSPLVE
PALAEFHLVAQSVTYRPALIPIVSNVTGRLATDADLASPAYWVRHVREAVRFTDAVRHLA
GKGVNRFVELGPDAVLTALTRTTLDSEDAIVEPVLRKNRPESRSLLTALAHLHAAGARID
WAAFYEGTAARPVALPTYPFQRERYWIIENPLGGDASAFGLTPAGHPLLGAVIPSPDTDG
VTFTGRLSVDTHGWLADHDVLGTVLLPGTGFVELALHAGEQVGYPALEELVLQAPLVLPD
RGGVALQVSVGPDDLGRRTIRIHSRHQDALRDTPWLLHAEGLLGTAPAAAGAELTAWPPA
GAREVRVSDAYELLFRQGYDYGPVFQGLKAAWREGDSVYAEIELPEEAHEDAALFGIHPA
LLDATMHALGVGEGVTGEEQTELPFSWSDVSLHAVGATSLRVRITKHGENNLSLDLADRS
GAPVASIGALTFRPVSPEQLGGGRQDTLFEIDWRAAAPVAPAAGSGFQAWDEVPAGPVSG
AVVFAVPQAGGPVPEAVRSVAGRTLDVVQEWLADPRFEGSTLVVATRGAVAVGAGEGVDV
VQAPVWGLVRAAQAENPGRILLTDLPAGGTGPEGLAEVIASAEPESAVREAGLLVPRLAP
VTDPAADGPVLDLEGTVLITGGTGGIGAHLARHLVTEHGAGRLLLTSRRGPAAEGAAELA
AELEGLGAQVTITACDVSDPQAITALLAGIPAAHPLTGVVHAAGTGDNGLIATMDAERLG
AVLAPKADAAWYLHEQTRELPLALFTLISSAGGLTLAAGQANYAAANTFLDALAAHRHAE
GLPARALAYGLWAARTGLTESIEEDIRLMAARGLPALEVEEALELFTSAHAQGRPALVPL
RVDTATLRSRADELPALLKGLVPQPTRSTARAADRGTDPAALVERLSALPAKEREQALMD
VVRAHAAAVLGHAGQDAVRADRGFLDLGFDSLTALELRNRLGALTGSRLTPTLIFDYPSP
VKLAAHLRELLFGAEDPEDDLSAATAEELFDILDGEEIFQ
>A0A8H2LJX0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Burkholderia pseudomallei|TrEMBL
MVNTKIAIIGASCRFPGGVAGLEEYWQLLKSERDAVTEIPPERFGTDFYRHPSKREPGKS
YTFSAGVLDNVAGFDAAFFGISPREATQMDPQQRLLLELAWEAFEDAGVRPADMRGSNCG
VYVGVAGTDYGNRSMDDLNAIDPYSATGNTLSIASNRVSYLFDLRGPSMSVDTACSSSLV
ALHQAVQALQSGEAETALAGGVNLLLHPFGFVSFSKASMLSPRGRCRAFDATGDGYVRAE
GGAFVLLKPLDRAIADGDTIHAVIAGSGVNSVGHSPGGISVPGAAAQAALLRSVYARAGV
DPQSLAYLEAHGTGTAVGDPIEARALIDVVSGARPADRPLLIGSVKTNIGHLETASGMAG
LLKAVLCLKHRAVPRSLHFSIPNPAIDFDGGRLRVVDRYMPLEAGNAPLTVGVNSFGFGG
TNAHIVLTEAPVSAVVADDVPTSATQAARAPSALVLTARSPNALGALANRYLAALENGGD
WQALAAAAARRRQWLEHRAIVAPADAAEGRAALAALARPAPEGGPSCVTTGRAPADAPRT
ALVFSGNGCQWVGMGNALYAEDAVFRAALDEVDALWCADGSPSLVDVMRGGPGAQWLAGA
GAEWLAATENAQPLLFAIQVGMIRVIDARGMRYDAAIGHSVGEVAAAWVTGALSLTDAVR
VIKIRSRAQAMTRGCGRMAAVGIGDAAARELIARHGLARRVEIAGVNSPDAVTLAGEPQG
LQVLEAALRGSGKFFQMLDLDYAFHSSHMDRIEPVVLAGLAGLRPQPGNGAFVSTVTGGA
LAGSELDARYWWRNIREPVRFGDGIAHLIEQGVRLFVEVSPHSILRTYVKQALAAAGVTG
VALPTLKRDHGSAATLRQAILAAIAHGASVDPDRFAPGASRAALPSYPWQRERFWLTPTV
EGYGLVNRRREHPLLGYRLHEHAFAWENQLDPAKLPMLADHVVDGGVAFPGAGYVEMALA
AACAFFDTPDAALENVEIRMPVVFQPQQAKLFRLVIEPRTATFTIETRDRMSDGAWTLNV
TGRMLESGNALGAAGVVPSDMLERLLALPAAHGDMLYANTAAIGLGYGPAFRWVRTVRVA
EGDDAALADVAAPDACGDARTLSAYRLHPALMDSGFHPLFALLAAHARDGEHPAYVPVQI
GRVDYLRGDTVARVLARIDRRSPHSIVAHFEFLDAQGAIVARLGACRFRRVDLVGRRQNL
PARFVYRLEAMPLPGDVDAAGLPAPDALLARAVARLDAGHDGRRTRHLTEILPLLDVLAS
LYVLQAFDALGAFAGTWRPAHGCAALAARLADILVEDGLAHRDGDRLVRDDAACAALPPL
DELWRGLLAESPAHVAELTLLAHCGSALPGVLSGAKDGTRLLSPTGHSLVEHLLAASPTW
QHVYALLTASVEQAVDAWQPARRLRVLELGATDGDVLQTLGMHLAPARCDHTIAATAGQL
AGFGADAQAAVTTVALQPGERLSLAADEAGPYDVIVANRALSGRRDVADALNAMRSWLAP
GGLLLLAESRRGRFSDIVFGMQAPSTQTDAPAPLAPADLEAALAHAGYVGVVRHVEQSLD
LEGTPMFVIARNPASAVAAPSGGDSSDLDTLARSEQWLVLHAPDVVGGFGARLADALAHA
GYPADIVEITHAADAIASLPAGQPAHVVFCAPETPLAEAATGDDLMAAQRNGVIALAALV
RVLGAQPNATTRLTIVTRGGAPFAGTAHAHPEQATLWGLGRVLANEHPELACRLIDVDCA
ADRIPEALIRELTGAALEEEVVLGAHGRRVPRMLTAAQDAARNDGAIARAAVLAFDAPGS
LRNLEWFALAESALGADEVEIEPVATGLNFRDVMYAMGLLSDEAVETGFAGATIGMELSG
RVVRVGSAVTEFAPGDAILGFAPASFATRVRTRAQAIAPKPERLSFEEAASVPTTFFTAY
YALIELARLRRGERVLVHGGAGGVGIAAIQLARYFGAEVFATAGSDEKREFVRLLGADHV
LDSRSLAFADEIRAMTGGEGIDIVLNSLAGEAMVRSIDTLRPFGRFLELGKRDFYENSHI
GLRPFRNNISYFGIDADQLMGALPELTARLFGDVMGLFAAGVLHPLPYRAFPAERAEDAF
RYMQQARQIGKVLVTYPCGTPAPTHGAARADSLALDPHGAYLVVGGTGGLGFASARWMVE
RGARRLTLASRSGELAVAARDEIECWRATLGVAVDIVSCDVTDAAAVDAMIAAIVRRDIP
LKGVLHSAMTIDDGLVRNLDDARMAAVLAPKVAGAWNLHRATRSLPLDLFVVYSSATTYL
GNPGQSNYVAANSFLEALVEHRRAAGLPGTFMAWGPLEDVGFLARHADTREALQSRIGGA
SITSGEAMIALERALVAGAAGEAVVRLDWHAVARGMPAAKARRYSLLQSHANGGDARDGG
TQLREEVLALPRDEAIALVAGTLQAQIARILHMTPDRIALDKSVLDMGMDSLMGMELGLA
VEEAFEVKLSVMAIAEGASAMTLAGRIVDSIGASADAGAGAAADSAHEAVAALAAKHAID
GDARAVLDIRPAPVAGQVSPTLEVAR
>B2J541|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MSNYTSETLSSSERILQALLDARTQLEAVEQKKTEPIAIIGMGCRFPGGVKNPQAYWDLL
RDGVDAIAPIPSDRWDVNRCYHPDHDAPGKMYVRNGGFINEVDEFDPEFFGISPREAEGM
DPQQRLLLEVAWEALENAGQPPESLKGSSTGVFVGIGSDDYSRLSVNSGDLNRIDAYSSL
GSARSIAVGRVAYVLGLQGPTLQLDTSCSSSLLGIHLACQSLRTGECNLALAGGVNLMLS
PAMTISFCKLKALAPDGRCKTFDASADGYSRGEGCGVVVLKRLSEAIADGDNIIALIRGS
AVNHDGKSNGLTAPNGLAQERLIRQALKEARVEPTQIQYVEAHGTGTSLGDPIEVLALER
VLGQGRSAEEALAIGSVKTNFGHLEAAAGVASLMKVVLSLSNRQIPPHLHFQNPNPHIPW
GKLPIVVPTALTPWSAKEGQRFAGVSSFGMSGTNVHIILEAAPSEEEQGSRGAGEQGRSC
SNLFTVSAKNEVALRQLTQSYQEFLEAQPEISIDDVCYTANVGRSHFDHRLAITTESIAE
LQQQLAAFNAGNETAGVLTSPVRDTLSKIAFLFAGQGSQQVGMGRELYATQPIFKVAIDQ
CADILTRLDVPLLEILWGNSSHLLDQTAYTQPAIFAIEYALDQLWQSWGIQPDAVLGHSV
GEYIAACVAGVFSLEDGLKLIVARSRFMQALPSGGAMAAVLVDKSKLLEVLNIYKNEVVI
AAYNAPGSFTIAGPVAAVESISQTIAAQGGKTQRLSVSHAFHSPLMEPMLGAYATIANTI
TYHQPRIPLIANRTGQVAGAEIATPEYWVRHVREAVQFEASIQTLHEEKYELFVELSAKP
TLLGMARQCLPESTGVWLPSLRPGQSDSHSLLTSLGQLYVSGVTVDWSGWAGNRPSRKIV
LPTYPWQRQRYWLKSLSGKPTSKLHPLVDKQLRSPLSKQTFFETRFNTELVPFIADHLVY
NEIVVPGASHLSLLLAAAELTFGKPGCLLENIVFPKALAIAKGKERTVQLALTPEESGNL
AAQVLSFENPSHPQEQVSWIVHAIAQVSANNTTLKPVSWSEIQKRCNQEIPGADLYQAQW
ERQIELGASFRWLNTVWLGEREALGCLQAPPAAFDAAEYQLHPGLIDSCFHLILAATGTI
NGDETFIPLSIKQFRFFQRPSSDVFWCHARLQHGTESQEDKRVGDLYLFDDAGQIIAEVI
GFEARKASRAVLLNSLQSEGRDSLYQIHWQLQENVASPVNHEPGNWLIFTDGTENGLELA
QQLEQQGHYSILAEVGEIYHQLGSQHYQLDPTEPEHFRQLLQDIPNLDGVIHLWGLAEDT
TENLSLQGLDKAQTLGCASVLHLVQALVQSQQQTQPRLWLVTRGTQAIDSNLEPLQLSQT
TLWGLGRVIAIEHPELNCTRLDLPLTATEDIQILLAELFSTDTEDQIAYRQGKRYVARLE
QVRAQFTKSPIPVTSESTYLITGGLGALGLEVAQWLAQQGAKHLVLVGRRSPSTDAQNAI
ARLATAGVEVTIITADITNPQEVAQCLQQIRSSHPPLRGIIHAAGVLDDGLLLQQSWERF
SRVMAPKVAGAWNLHTLTQDLPLDFFVCFSSIASLIGSVGQSNYAAANAFMDALASYRRG
LGLPGLTINWGPWAETGMAANLGSREQARLKDQGIVPINPEQGLQVLGELLTQQIPQVGV
MTIDWSLFVKQFSSRTNLKLFEVLAPTSTKVNERSQFLNQLEDSPPNTRQQLLATHVRSQ
IAQILGWNSPEKVEPRQRLFDLGVDSLMAIELKNRLESSLGCSLRTTLLFDYPTLEALVD
YLSREVLALESTTAATVEIAQDDELEALLSELEQMSEFDIQNKLVNLSHA
>S5YCN0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Paracoccus aminophilus JCM 7686|TrEMBL
MTFLAPQNSAFALVGIAGRFPGAPDMDSLWSLLNEGRFAIGPIPADRWDATRQLDPEKHV
QAVGGFIEGVDQFDPGFFGISPREAEDIDPQQRLMLEASWTALEDAGIRPETLRGSRTGV
YVGASWHDYEILRKERGLHASQHTAVGNALDVIAARLSYFYGLTGPSLTVETGCSSAMVA
LHLAAKALATGEIDAAFVGGVNLILAPDVSIGLTRFGGLSAKGRCSAFSEEADGFVRGEG
VVALYLKRLDQAQADGDRIHAVIAGTGVNNDGGGDSLVTPSPAGQEDLLTTIYTGSGLNP
DKLVYVEAHGTGTKVGDPIETGAIGRTLAARRDPSKGPLAIGSVKTNIGHLEATAGLAGL
AKAVLAIRHREIPASLHSESLNPAIDFDGLGLEVVRAPKTLPEGSDFLIGVNSFGWGGTN
AHAVLAPPPEAVRPVAEEADTTQGPVFLPLSAQNADRLRARAADLAALVAESDLRLDDIA
ATLAHHRSHFAERAGFVGSDRATLAEALTALAEDRELAGLSDQHAEPQTAKTKGRVAFVF
PGQGSQWAGMGAQLIQQSPVFAARIADCAAALRPYVDWDLEALIRGDLGSDWVERVDQVQ
PALWAMKVALSEVWRAQGIIPDVVVGHSQGEVSAATVAGILSLDDAARIVALRSQIIRRN
AGKGGMLSVDMSLEEARAQLEGFEDSISIAVNNGPSSCVLSGDIEALETLQTLLDADEVF
NRLVKVDYASHSHHMDEFKEELHGVLVGIEPKAGEVTFFSTVDLEAKAGTDLDPTYWVRN
LREPVQFFGAMSALFDDGVTHVIEVSPHRALLPSLQQIAALRDDPAIALSTMQRDRDTVE
DVLGMCARAYVAGLMPMGQRPQGALVDLPAYPWQRQSFWAAKARPQGAARKGLEVSLIPS
PAEQDAWEGLVDISAEDNPWLADHKVHEATVFPGAGMVALMLAAGRQRFGALPRRLRGVQ
LLADLTLGEEPRRAALMLRDTLSAGGDVALASLPEGATDWVTHATAIVEQMLPPTAAPIC
PEALDAADAVTPDDFYAACTARGLSYGDAFRGVTALQVASDEALGQITLPQPCTASARAH
GLHPALLDSALQVTLALESAEATVVPVAIDEIRLFIDPEAPITAVSVHARRNGDKRFDLD
LFTAEGQPLAAIIGLQLETLVLDTSADADERLHRLAFIPETRREKTEAARVWLIAGSTGA
EALAGALTGLGATAALGDAPGEHHTAVAFVAPDAEAGLDAQKAAIMALAQLVRACAAQSQ
APRLAVITTQAQAQLYSGIADPGAALFWGFVRVLRREHPELEPIVIDMAPGSEAEVAAEL
HGWSGDDQVVLAGEIRLVGRLKRGAPDRASEDETVKTAWQLPAQPFRLVSGAAGYYDELE
YRPLQRSAPGKGEVEVEISAAALNFIDVMKAMGTYPGLDARSARLGGEFAGIVVAVGEGV
TGLTPGERVVGCGFGAFASHATVPSAHVRPIPQGMSDAEAAALPLVMTTAWYGLVDLADL
GTGETVLIHSAAGGLGLAAIQVARMLGAEIIATAGSKEKREMLRAMGIEHVFNSRDLSWA
EKVREVTKGRGVDVVLNSLTGMAIPLGLEALAEDGRFIEVGKKDIYAGRTINLSAFRKRL
SIASVDIAGLMEKRVARFGRLLGDVWAAVADGDLTPLPILPYSFAAAGEALRTMGKGDHI
GKFVLTDPASVTNIAPAPFTEGELRGDGTYLITGGLGALGLSLAEHMAARGAGGLALLGR
SAAKGEALTRIEALRAQGVAVRSFAVDVSDRAALAEVLAKIRAEMPGLRGVVHAAGLLDD
ALIDNMTEDQLARVLAPKIDGALALDALTEDDPLDLFVLFSSAAALFGNAGQAAYAAGNA
GLDALAEARRARGKPALSVQWGPFADIGLAAADAIRGDRLDERGMGNFSAEDGWLALTRL
LQQGETVSGFVPINLRLWFDAYPDTAALPSWSLLLEAARGNTQASNGAQAFRAELEAAPA
ESRDELAEAKVRELAGRVLRMDPQAIGRETPFKALGLDSLMGLELRNRLEVAFGLKLSPT
LLWTYGNTKAIAPVLVERVFEVAA
>A0A1B8YN19|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Photorhabdus namnaonensis|TrEMBL
MQLFNLDWVKRNIVLPEAPLLTQCTVISRNTDFTHRVKELIEAKGIDVVDIDLGADPASQ
IDSIGDTDTLIYLASPEEFLNAADIVANELREFESLRLIANKVAERHHDVKPRLWVLTQG
VQASGEQFNTVGLSGSSLWGLGRVIAKEYPSVDVGLIDLPVKQVGNEEITSVLAIMANQH
QQREFLIHDQCIWQRQVEPLAVSQEKTEIKQNANYLVIGGFGDTGRMLAESLFAAGARHV
TLMGNFAPPANLITESEQRKAQGCNLRLFQGDVADIEDVKAVLRRIDRTGHPLRGIYHLA
SVVEGALLTTLNSRSVEKVFRQKIAGSWNLHLATQELSLDRFMTFSSLSEIIGVVGQGAC
TAANAFVDALMRYRVSTGLSGTAIAWELGNDIKSVIDTVIRADIAHYAGLIAGNFSQIAL
ERLIYQQEPVNDIEPAFGSTQSDDAMVTPEKLSHEEQRQAMTEIVIEELKKLVAGGNVTA
DTKLSEIDMDSMSAVTIAQRLRGIIGKLVPMSVFFDDCSISELVEKLKRYF
>A0A4P6Q2W4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomonospora litoralis|TrEMBL
MSDEKLLAYLRKVTGELHEARRKLKEAPAADADDPIAVVAMSCRLPGGVASPEDLWELLA
DERDAVSGFPTDRGWPDDLYSDDPDAPGKSYVNRGGFLHDAAAFDPEAFGISPREATAMD
PQQRLMLELGWEAFERARIAPSSLRGTATGVFAGACSFHYEGDYTDAPEDLGGHLITGNV
TSVLSGRVSYAFGLEGPAITLDTGCSSALVAMHLAARSLRQGECSLALAGGVAVMSTPGV
FVEFSRQRGLAPDGRCKAFGAAADGTGWSEGAGFVLLERLSDAEAAGHPVLAVLRGSATN
QDGASNGLTAPNGRAQQRVIQRALEDAGLEAADVDAVEGHGTGTRLGDPIEANALMEAYG
RRRPEDRPLLLGSVKSNIGHAQAAAGVASVIKTVLCLDRGRLPRTLHVDEPTPEVDWSRG
GVELLTEPVAWPRGERVRRAGVSGFGVSGTNAHLIVEEPPEPSPAAVHAGADADPFGTPL
PWVLSARGEQALRARAAQLHAHASAAPETVQDIGYSLATTRSSYEHRAVVVGEDRDRLLA
GVDALRAGASSPAVVSGVAETPAAPVFVFPGQGSQWPGMARDLLESSPVFRKRMEECADA
LAGHVARSPLDVLRMTPGGPDDDRVDVVQPALFSVMVALAELWRSYGVEPAGVIGHSQGE
IAAACVAGALSLEDAARVVALRSRALRTLAGTGGMLSLGLPPGETRELLAHWEGRLSLAA
VNSPGDTVVSGDTEALASLQQAAADRGARARMVNVDYASHSAHVEEIRQTLLGDLAPVAP
GAAGVAFYSTVTGDRLDTAALDADYWMRNLRRTVRLDAAAEAAHRAGLRMFVEVSPHPVL
TFPLQQTLPEADVLGTLHRDDRCARRFLVALGEAYAAGAEVDWSAAFDPAAGRRVPLPTY
PFQRRKHWLPPRRPAAAAPVDRLDTWHYRPSWSAVTEVAQGRARGLWLLLVPAGAGTGAG
TGTGAVADALRRSGAETCSVEVDRPPERAALAARLRDAAQDREVAGVLSLAADAEDVSGE
RGGGVPEAVLGTLVAHQALGDAGIGAPLWCATREAVSTGAGDPAPRPRQAALWGLGTSLA
AERPERWGGLVDLPADPGPRELDRMASVLGGGGEPQCAVRPGGTFARRLLRASSATAEAW
VPDGTVLITGGLGGVGGRLARRLARGGARHLLLLGRRGLDTPGAKDLCQELDELGATVMV
RACDAADRAALAEAIGEIPEEHPLTAVIHAAGVLDDAPADRLGPKQLRTVMSAKAASAWN
LHELTRGLPLTAFVLFSSAGAVLGSAGQAGYAAANAYLDGLAEHRKALGLPATSIAWTVL
KDSGMVGPDAEEWFSARGARPMEPEPAFEAMRRAIETGAPHVVVGDIDWGRFASLDGITA
PGPLLAEIPEAARSAAEAEGGDARRLVLGRDADEALRSLRDLVAGQVAAVLDYGPDDAVP
RERPLKELGFDSVTSVALRNRLGAACGLRLPVTLAFDHPSVAAIAGHLYDELSPDTGADA
AAELERLESLLADGGDLREALVERLRSMLWKWDRGPAAPDDAEDAGRADDLRDATDEEMF
QLLDNELGTA
>A0A3N6D556|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI91-18|TrEMBL
MESTIDARFWDAVEREDVTALAEALAFDAPDAIQSLGTVLPGLSSWRRQSREQSTVDGWR
YRVVWKPQADAVTKPRLSGTWLAVVPEAPAGAAGDTVAAVLRTLADRGAEVRTVTVAAGA
AGREALTATLKDATAGAPAAAGVLSLLALGGDAAAHALSQALGDAEVAAPLWCVTRGAVV
AGRSDRITDPGQALVWGLGRVASMEQGGRWGGLVDLPGTDAADGRTLERLVGVLAGDAAE
DQVAVRSSGLFVRRLVRARLADSPAVREWRPRGTTLVTGGTGVLGGQVARWLAGNGAEHL
LLASRRGAEAPGAAELREELTALGARVTLAACDVSDREALAGLLATVPADQPLTAVIHAA
AVVDDGVIETLTAEQVAAVLRVKVDATRHLHELTRDLDLSAFVLFSSFAATFGAPGQGNQ
APGNAFLDAFAEYRRADGLPATSLAWGRWGSADGDDSAAGDRMRRHGIIAMPPARTLASL
QHALDRDETTLTVVDMDWKRFTLAFTADRPRPLLLELPEARRVIESAERESAEDLAGGVP
LTQQLAGLPDVEQERLLLDLVRTAVAAVLGHADLTAVEAGRAFKELGFDSLTSVELRNRL
GAVSGLKLPASLVFDHPTPAAVAAYLRAGIVPDAAAGGAPLLEEIDKLESVLERGTADNV
VRARVTMRLQSLLAKWSDTEDPAEEDPADEAEQVQDASDEELFALINNGLGRY
>A0A5P9PHD4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Amycolatopsis sp. YIM 10|TrEMBL
MSSERTRADADELVPWVLSGRSARALRAQADRLHSRVDGQDERPVDVGLSLTARSALEHR
AVVLGTGRAGLLSGLRALADGEPSPDVVHGEASADPRVAFAFGEPEADWLVGGAALLDSS
PVFAESMADCAKALAPLLSWDPREVLRGTENSVAPDVLGPVGWSVLVSLAAVWRSFGVTP
HAVSGTGPGAVAAACAIGALSIADGARIVAVHGRILAQGLTGEVRDRLLSVLAGIRPRAA
SVAFYSASTGAPVDGAALDADFWNAGLDEPGRIELAIKALRGDGFEVLPDLRPGDVAAAL
AVAWVRGVPVRWPDLFSDAKPVDLPTYAFQRRRYWQQPDTAHTDVVGAGLDRVDHPLLDA
RLEPAGTDEFLFTSRLSLLSHPWLGEHRALGSVLLPGTAFVELALRAGDLAGCAVLDELV
LEEPLLLPERNGVQLQVAVGAPEETGTRTVHIHSREEDTDSPWTRHATGSLSIGAPVDAF
EPTAWPPEDAVPVRLEDAYRDLRERGYDYGPAFQGLRAAWRRGEELFAEVALPEHAQADA
GRFGLHPALLDAALHADLVEDSGAPVLPFAWTGVRLHTSGATALRVRLAPAGADGTSLEA
ADEAGGPVLTVDSLVTRPVAAGQLGDRGLVPYRLTWVPVAAGDAPALDDLAILGTADFGF
GDSVPRYRDLAAFDDGAVPALVLWRCDARAGDVLTGLRSAAHEALGVAQEWLRDERFAGS
RLVVVTENAIGPDAGGPAVASVWGLLRAAEAENPGRFRLLDVDGTSGSDGLLTALGAEEP
ELILRDGEPRAPRLAPATGLERTTDFAAEGTVLITGGTGGLGRLLARHLVTTHGVRHLLL
TSRSGPHAPGATELRDELTTLGATVTVAACDAADRDALAGLLAGIPAEHPLTGVLHVAGA
VDDGVLGALTPERVDHVLGSKADAAWHLHELTADHELAVFALFSSAAGTLGAAGQANYAT
ANVFLDALAAHRRDLGLPAQSMAWGLWGIGAGMAGELAETDLRRLDRQGFPALSAAEGLA
LFDAALGTDDPMLLLLRLDLPALRAQAASGLVQPTLRELVRVPSKRAARPGGDGSALADR
LATMTGTERLRVLLDLVRTHAAAVLGHPSMAAVEPDRAFQELGFDSLAAVELRNLLLGAT
GQRLSATLVFDYPNARAVAEHLAAAFTDPVVSAAPVVTTPVDDEPIAIVSMACRYPGGVR
SPEDLWELVVQGRDAIDEFPGNRGWDVEGGYDPEPGVPGKTYTKSGGFLYDADEFDAEFF
GISPNEALGMDPQQRLLLEASWELFERAGIDPGSLKGSATGVFTGVMYHDYPAASATGSI
ISGRLSYVYGLEGPALSLDTACSSSLVGLHLAVRALRSGECSLALAGGVTVMATPETFVE
FSRQRGLSGDGRCRSFGVGADGTGWGEGVGLLLVERLSDARRLGHPVLAVVAGSAVNQDG
ASNGLTAPNGPSQVRVIRQALGSAGLSPSDVDAVEGHGTGTSLGDPIEAQALLTAYGQGR
EEPLWLGSIKSNMGHTQAAAGVAGIIKMVQAMRHGVLPKTLHADEPTPQVDWSSGSVELL
TDARPWPTTGRARRAGISSFGISGTNAHVIVEEAPADGLAFLFSGQGAQRLGMGRDLYET
YPAFAAAFDAVCAELDPSLREVIWGDDPDLLNQTEWAQPALFAVEVALFRLVESWGIRPD
FVAGHSIGEIAAAHVAGVLSLSDAAALVTARGRLMQQLPAGGAMVAVQASEQEVLPLLSD
QVSIAAINGPEAVVLSGEEAAVLKAADALGCKKTRLKVSHAFHSPLMEPMLAEFAAVVEQ
LSLREAVLPFVSSALEADVTSPDYWVRHVREPVRFADAVRELESRGVARYVELGPAAVLS
LLGPRCVSEGTFEATAEFIERVGPSVRAQVVPWVLLAKNEEGLRAKLRSLADAPLDASAT
DIGFSLATSRAALPHRVAVTGTSRTELRKALADLADSNTPVGVTANSAGLTAFVFSGQGA
QRLGMGRELYETYPAFAAAFDAVCAELDPSLRDVIWGEDPDLVNQTEWVQPGLFAVEVAL
FRLVESWGVRPDFVAGHSIGEIAAAHVAGVLSLSDAAALVTARGRLMQALPTGGAMVAVQ
ASEQQVLPLLSDQVAIAAINGPEAVVLSGEEAAVLKVADALGCKKTRLKVSHAFHSPLME
PMLAEFAAVVEQLSLREAVLPFVSSALEPDVTSPNYWVRHVREPVRFADAVRLLEERGVT
TFVEVGPDAVLSSLGGFTPLQRRNKSEELELVTAVANIHTRGVPVDWHAFYNGRGARRVD
LPTYPFQRKPFWLTPPDTATDLIGIGQAPARHPLLSAMVLLPDSEGLVLTGRLSTTAQPW
LAEHELHGLPVFPATGLVELALHAGAQLDCGALAELTVEEPLVLAEHDVAIRVTVGAADE
SGARSVRIDAQHDGEDWTRHATGLLTPAPVPEAATFEWPPSGATAIDDLPARLRAAWRRG
DELFAEVDLDGSAEAGQFGLHPALLDAAFQLDDGRPYRWREVTLHTTGATGLRVRIADGT
VTATDLDGKRVFSAASVEFRTISAGQLGGGGSLYRLDWQPVPNSQPASTVELSEIGDEIP
ALVRYSCPRPDEENLLDGIREATAAVSDVLESWLADDRFEHAKLLVHTRNAVAVRDEAVD
LTHAPIWSLVRAAQAEHPGRIVLVDGDEFTGLPADEPAIAVRGGRTYVPRLVRSSTVDKE
SPWGGTVLITDGTTGAGAAAARWLVTEHDVRHLLLLGPDAPELHAELAELGADVVFDDRD
PADPAALAALPSGQPVTAVLHTNSDLTAAWNLHQLIGESAALLLISSSTGLLHGAGQRDL
AMAAGFFDALARHRHAAGLPGASIAFGPWEGNNDETYLRRMAVLGLTPLSPAEGLTMLGR
ACHAAEPVVVPLRLDHAALRATPDLVPAVLRAVVRIPAKRPGAAAPAGLRARLDGLGEDE
RNRVLLEAVRADVAAVLGHPSAELVPSDSPFQELGFDSLAAVELRGRLNAATGVELPATL
AFDHPTARAVAEYLRTALEPPQADPLAEILAEADRLEAALAAAEPGADGAGRITARLEAM
VRAWRDGAQDAPGAGDFDSATDDELFKALDDLEIG
>G6FYL6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Fischerella thermalis JSC-11|TrEMBL
MAPSRIEVDFAKLQKEVSNCEQTLDKLIKVKKMMSANATEINKINKKLHQNPVAIIGMAS
IFPESKNLQEYWEKIIRKVDCITDVPPSRWNINEYYDPHPKTPDKTYCKRGGFIPDIEFN
PMEFGLPPNVLEVTDVSQLLGLVVAKAAMEDAGYGEKSQFNRERTGVVLGVALARQMSMP
LATRLEYPVWEKVLKSSGLSDEDTQKIIEKIKSAYVQWEENAFPGMLANIVAGRIANRLD
LGGMNCVVDAACASSLGALAMSISELIEHRADMMLTGGVDTDNSIVAYMCFSKTPAVSPS
QNPKPFDAQSDGMMLAEGIGMLVLKRLEDAIRDNDRIYAVIKGIGTSSDGRYKSIYAPRP
EGQVKALHRAYEDAGFSPTSVGLIEAHGTGTMVGDPAEVTALKEVFGENNCKKQHIALGS
VKSQIGHAKAAAGAASLIKTALALHHKVLPATINVTKPHPKLGLENSPLYLNTETRPWIR
SQAEVPRRAGVSSFGFGGTNYHVVLEEYSSEHDRPYRLHHTPQSVLLFASTPEQLLTRCQ
EILHQLQSPEREQHYAELIAACASLEIPATNARVGFVAESLTEAYKALQICIDLLTKKPQ
AESWDHPQGIYYRKAGVATAGKVVALFSGQGSQYLEMGRELVINFPCLRQTYGDIDQLFY
KDDLQPVSEIVFPPPVFDTAQKQAQVAALQRTEYAQPAIGAFSVGLYKILQQGGFKPDFV
LGHSFGELTALWAAGVLSEEDYFFLVKARGQAMAAPNDPEFDAGAMLAVKGDISQVEEVI
KNFPLVTIANLNSPRQVVLAGAKAEIAQVQEQLKAKAYSTVLLPVSAAFHTPLVAHAQKP
FAQAIEKVSFQEPTIPVYTNVTGERYPNEPQAIQKILKQHLINQVLFKQEIENIYAQGGY
CFIEFGPKGILTSLVKDILGDQPHLAVALNGSYQKDSDRCLREAVTLLRVAGLPLQNPDP
YQIEQKVPEVPKNKLLTVQLNGSNYVSEKTKQAFVKALQDGHQVSLPKTKDNSSEVNTPL
TLPVQQTDSLPVNPEHTNGNHAGVAQSGDEVMNRKDAKYAKKGFFDRQIKENHPANMHSQ
AEQSTSLEAPQNYQLVLDSLEFTLIEFNRHQRDILRVHEKSLLHQTEYTKIFFQLMQQQN
LLLGNSKFPHQHADTKQIIISYSERSIMRFHQHHGETLRVHEQYLNHQTEQTKNFFQLLQ
QHYDQLLASISTEELTESLPQTTSIVSYQDSSAVSFRANGGTTAAVATPANDFVTNFEPV
LINGASHGVHHSKSNGNGTYKNGNHDTKSVTVTISDTPAVPSPDVPSVPLTIDEATLSQT
LLNVVSDKTGYPVEMLELSMDIEADLGIDSIKRVEILGGLLELYPDLPKPNPEELGQLRT
LGQIVEYMRTLVPAISPVESAPIQTAQEVALDEAKTSEESDVVTQQIEDAESKDIHIASS
PVPVALPTLEEPTSSLPSLDFTDLSQILLNVVSEKTGYPVEMLELSMDMEADLGIDSIKR
VEILGALLELYPNLPKPNPEELGELRTLGQIVDYMKQQAETLEKKTFPVESNSQPPKLNH
NIRRSPVKLKVLPEPDVLDFTLPEQHIALITDDGTTTTSELALALGKRNWKVVVLSFPQT
LIAEQLPLPEGINRVVLANLSEEHLQNQLEAIASEYGQIAAFIHLNPANYDASNCVRYLE
TEKALLRHVFLIAKHLKAPLNQAANQGRSCFLTVAHLDGEFGLGYKTNFGAISSGLFGLT
KTLNQEWEAVFCRAIDLSPDLDIHTSVKYILAELHDPNQLIVEVGYSSHGRTTLVCEEGR
GGQGSNLPSFNPQSQVFLVSGGAKGITAQCVIKLAQHYQCKFILLGRSSVDPEPVWAEGC
SNEGELKKRIMDDFIAKGEKPTPAMVQKKYKAIASRREIDTTLRAIEQAGGQAEYLSVDV
TDATQLQEQLNVAVERLGAVTGIIHGAGNLADKRIENKTERDFETVFAAKVTGLENLLRC
VSPSQLNYLVLFSSVVGFYGNIGQSDYAIANEILNKSAHLVKRNYPNCHAVAINWGPWDS
GMVTPELKKAFAERGIETIPIEVGTQMLVDELAQVNQQTTQVVIGSPLLYVPQSCNSDLQ
KYRIQRRLTLAENPFLQDHVIAGRPVLPATCALAWIANTCEQLYPGYKSFNCPNFKILKG
IIFDETLAKEYTLDLQEISKNDIAEIEFDAKISSKNQEGKIRYHFSGQIKLKRQIPTAPV
YNSLNLKQEEIILGSTTSLYQDGAASLFHGPSFQGVKTILNISPEKITIECNLPKLRTRQ
QGQFPVQIFNPYIADVQIHALWIWTQYFYQEGCLPSEIKLFEQFAAIPFNQTFYVSCEVK
SKTDSSVTVDVIAHDHQGKIYNRMIGAKGTILPTKR
>A0A5P9PXE2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Amycolatopsis sp. YIM 10|TrEMBL
MNAPNEKVVEALRVAMKDAERLRRQNRELVAAASEPIAIVAMSCRFPGGIESPEALWDLV
ASGGDAISGFPAGRGWDTESLASAETDDRGTSMSLQGGFLPGVADFDPGFFGISPREAVT
MDPQQRLLLETTWEAIERAGIDPSKLRGTRTGVFVGTNGQDYSHLMVRSVADATGDIGTG
IAASAISGRVSYELGLEGPTVTVDTACSSSLVALHLAAHALRTGECSLALAGGVNIMATP
GSLVEFSRQGGLARDGRCKAFSDDADGTGWSEGVGLLLLERLSDAQRNGHEVLAVVRGSA
VNSDGESNGFTAPNGRAQQRVIRQALERCGLEPSDVDVVEAHGTGTPLGDPIEARSLLAT
YGQDREHPLLLGSIKSNLGHTQAAAGVAGVIKMVMAMRHDLVPKTLHVSKPSTHVDWTTG
AVRLLTEATPWPETGRAHRAAVSSFGVSGTNAHAIIEQAPPMTVEVLPDTSGRAPRSGSV
EGGGGLAGGTEPAVVPWVLAGRTPAALRDQVTRLLSVVDDERPVDLALSLATTRTSFEHR
LAVVGGSRDELRESLSAWLEKGTARGVVTGEVNGRAKLGVLFSGQGAQRIGMGRELYGRF
PVFAGAFDEVLAELDRHLDGSLRDVVWGDDPELLNQTGWTQPALFAIEVALFRLAESWGL
TPDFVAGHSIGEIAAAHVAGVFSLEDAAGLVAARARLMQALPAGGAMVAIKATEDEITLT
EGVSIAAVNAPGSVVIAGDEAAVLAIAANFEKTTRLKVSHAFHSPLMDPMLAEFRRFAEG
IAYAEPSIPVVSNLTGELATENELRSADYWVRHVREAVRFADGVRALAAAGAGVLLELGP
DGALSGLAQQSVDLPVAPALRKDRGEEAAILGALGKLHVNGVAVDWSAVLDGTGARRVPL
PTYAFQHEKYWPSVSVRSGDISGLGLDSAEHPLLGAATTVAGSGELVMTGRLSLESHPWL
ADHAVGGAVLFPGTGFLELAMRAADQVGCDRVHELTLVVPLVLAERSSVTVQVWVGSPDA
AGRRPVSVHSQQGGADSWVQHAGGTLSDGAAVAPFTATEWPPAGATALDLDGFYERFAET
GLTYGPVFQGVKAVWQGDGEIFAEVALPDSVEDAGEFGVHPALLDSALHASLFVHPDRED
SGLLPFSWSGVSQHASGASTLRVRLAATADDAISVTAVDVQGEPVLSVESLALRSATAES
TARAQGEQDSLFRLDWVTQPGAKSTEDTRWAVLGTGEAALGAAVATTGGSRVDSLDELAE
LSGGVPDMVLWPVASGTDGAEAVHELTARVLGTVQDWLADQRFGDSCLVVVTRGAVAAGD
ENVHDLPAAAVWGLVRTAQSENPGRLLLLDLDQADTDVLGTLPALRANGETQAAAREGEL
RVGRLARLASGTALVPPVGVPWRLDSGRKGSLDGLTLAPAPQLLDPVEGRGVRVAVRAAG
LNFRDVLNALGMYPGDAGLFGSEAAGVVVETGPEVTDLQPGDRVMGMLFGGMGPLGVVDE
RLLTKLPDEFSFETGASIPLVFLTAYYALVDLGSVQPGEKVLVHAGAGGVGMAAVQLAQH
LGAEVFATASEGKWDTLRGLGLDDDHIASSRTLDFEAKFPQVDVVLNALAGEFIDASLRL
LAPGGRFLEMGKTDLRDPASLPEVSYQAFDLGWVDPDRISAMLAELKELFAAGSIRPLPI
VTWDVRRSRDAFRFMSRAQHIGKIVLTVPSGWDPDGTVLITGGTGGLGGVLARHLVTRRG
MRNLLLVSRSGPAAPGAVELRDELTEAGADVTVAACDVADRDALEALLAEIPNLTAVVHT
AGVLDDGIVGSMTPERLDTVLRPKVDAAWHLHELTRDRDLAGFVLYSSVSGVMGSAGQAN
YSAANVWLDALAHRRRSEGLAATSVAWGAWTPEIGMTATVSDTDLRRMSESTNPLSVEQG
LALFDAAIGCDEALLVALNGGAGQDGPAQGHVPALLRGLMRAGRRTAASGTSGGEGLAQH
LLGLPEDERIRHLVELMRTEAAAVLGHSSPEAIGVDREFRQLGFDSLTAVELRNRLGAAT
GMTLPATLIFDYPTPRVLAEYLLDELLGAVEDLTEIAPRTSGTTDDPVVIVGMSCRFPGG
IDSPEDLWQFLLDGGDAITDFPPDRGWESDPTGGTEGAKGGFLADMAGFDTGFFGISPRE
AKAMDPQQRLVLEVSWEAIERAGIDAADLRGSQTGVFIGTGGQDYTNVVLRANEDLEGHA
STGLAAAVISGRVSYSFGFVGPSLTIDTACSSSLTALHLAAQSLRTGESSLALVGGVAVM
STPMSFAGFTAQGGLAPDGRCRAFSDDAGGTSWSEGVGVLVMERLSDARRNGHQVLATLR
GSAVNQDGASNGLTAPNGPSQRRVIRAALAGAGLAASDVDVVEAHGTGTKLGDPIEAQAL
LATYGQDRDRPLLLGSVKSNLGHTQAAAGVAGVIKTVLALRHGVVPKTLHVAEPTSHVDW
TTGSVQLVTEATEWPDAGRARRAGVSSFSLSGTNAHVIFEHTPVIEAEPADRDEPEIVAL
PVSAKTPEAVDGQLARIRSFLDDHSALDTAYSLVTTRTELEHRAVLLSTKDGLTEVARGT
AVDRPLAVLFSGQGSQRLGMGHELHARYPVFAEALDGVLALLDPAVRDVMWGSSAERLNE
TGYTQPALFAIEVALFRLVESWGVKPRFLAGHSIGEIAAAHVAGVVSLEDACTLVTARSN
LMQALPAGGAMVAIRATEAEVAPLLTDEVSIAAVNGPSSVVVAGDETAVLEIASNFEKTS
RLKVSHAFHSPLMDPMLDDFRAAIEGLTFGEPQIPVITSGDVTSPEYWVRHVREAVRFAD
AVSTLVTERAGVFLELGPEGVLSAMVAETAPDAVVVPVLRKDRPEEAAALTALAKLHVNG
VPVDWRSWFAGTGARRIDLPTYAFQHEKCWPSMATGARAGDVSGLGLFSTKHPLLTAAMA
VAGSDEIVLTGRLALTTHPWLADHRVGGRVVFPGTGFLDLVIRAGDLVGCDRVEGLALMV
PLAFDDRSGVAVQVRVGEPDDHGRREVGVYAQPADGTGREWTQHVGGTLSTSESVPEGIG
EWPPAGAEPVELDGHYARLAEEGGLSYGPVFQGLKAVWRAENEVYAEVELPEQVEDAAAF
GLHPALLDAALHAIVFLDEESRGLPFAWHGASLHAVGASVLRVRLSRTGGESMSVTAVDV
EDAPVLSVESLSLRASSVDEAPKPQGQVNDSLFVVDWSPAELAADRPAAKWALHGEDLFG
LTPTAEAGEADAILAQFAGAEGVDAVHELTARAQELIRDTLADESGKPLVLVTRGATAVG
GEAVRDLAAAAVWGLVRSAQAENPGRFLLADLDETAESAAVLNNLTELLELGETQVALRA
GTAHLGRLARLSASQALVPPEGTPWRLATANKGSLDELILAPSPDLLEPLTERQVRVAIR
AAGLNFRDVLNALGMYPGEAGVFGNEAAGVIVQTGPDVVGLKPGDRVMGMLFGGFGPEGV
VDERFLTKLPEHWSFEEGAAYPLVFLTAYYALHDLAAVQPGEKVLVHAGAGGVGMAAVQL
ARHFGAEVYATASEGKWETLRGFGLDDDHIASSRNAGFEAKFGQVDVVLNALAGELIDAS
LRLLGEGGRFLEMGKTDLRDPASLPGIDYQAFDLGWVELDRIQQMHNELKELFDGGAIEP
LPIRTWDVRRAKDAFRFMSRAQHIGKIVLTVPGQWDAEGTVLITGGTGGLGAELARHLVG
TRGVRHLLLTSRRGPDAPGAVELQAELIAHGADVDVVACDASDRESVAALLAGVPDEYPL
TAVVHTAGVLDDGVVGSLTPDRISKVLRPKVDAAWHLHELTRDLDLADFVLYSSISGVMG
AAGQGNYAAANSYLDALATQRRAAGLPASSLAWGAWAGAGMASDMDAAALERMARAGTPA
LSVELGLSLFDAAITVDEPLVVPASIITGSNAAPMAVPPMLRGLMTTGRRKAATGGRGSG
ALRKLAGLGRDERVKALVDLVRTEAAAVLGHDSTDAVDAERDFRQLGFDSLTAVELRNRL
GQATGMSLPATLVFDYPTPLVLAEFLNTELFGDDEPVDELPAVAKVADEPIVIVGLSCRF
PGGVNSPEELWDLLVDGRDAISGFPEDRGWNLEWLAGGGPGSSVTGQGGFLPGVAGFDPG
FFGISPREAVAMDPQQRLLLETSWEAIERAGIDPASLRGSRTGVYVGTSGQDYSQLVMGA
QESMEGHAGTGTSASVISGRLSYTFGLEGPAVTVDTACSSSLVALHFAAQALRSGECSLA
LAGGVTVMATPGMFMEFSRQGGLAQDGRCKAFADSADGTGWSEGVGVLVLERLSDAQRNG
HKILAVVRGSAINQDGASNGLTAPNGPSQQRVIRQALASAGLSTSDVDAVEAHGTGTALG
DPIEAQALLATYGRNREEPLWLGSIKSNLGHTQAAAGVAGVIKMVLSLQNRVLPRTLHVE
QPSSHVDWNTGKVSLLTAPREWPEADRPLRGGISSFGISGTNAHIILEQAPEVEVAEKPE
PTFTPAVVPWLVSAKTEAALDAQIERVRTLSGPAVDIGYSLASGRSRFEHRAVLVDGAEV
ARGTASTRKLTFLFAGQGSQRIGMGREPYERYPAFAKAMDEVFEHLDIREVMWGEDQEAL
NQTGNAQPALFALEVALFRLAESWGIKPDALAGHSIGEIAAAHVAGVLTLEDACTLVSAR
ARLMQALPTGGAMVAIKATEDEITLTEGVSIAAVNGPSSVVIAGEEAAVLEIAAGFEKTS
RLKVSHAFHSPLMDPMLDDFRAAIEGLTFHEPSIPMPGEVTTVDYWVRHVRDTVRFADHL
KPDTAYLELGPDSTLSAMAAEVAEIAVPSLRKDRDEEKALVTALARLHVAGVRIDWTAFF
DGTGAHRVDLPTYAFQHEHFWVEGSGFGTQFGAGQDPVDQAFWAAVEREDLATLAETLEL
DDNTVSAVVPALSAWRTRRHAQSTVDSWLFREEWQQLSLDESASGSWLVAVPADADEIWT
GALIGSLGAEVTRVEITDRASLAEQLSGITADRVLSLAGATETTTLFQALGDAGVLAPVW
AITRGAVSIGRTDPVLDAGQAAVWGLGRVAALEQPQRWGGLIDLPEKLDDRVLRRLPAVF
GSTEDQVAVRPHGVFGRRLVAASGDRAVWEPSGTALITGGTGALGARVARDLARRGVDRL
VLVSRRGPDAPGAAELREELTGLGADVTIAACDVADRDAVAALLDGIPDLTAVVHTAGVL
DDGVLESLTPERFEAVFAAKVDSARVLDELTREKDLAAFVLFSSVAGAVGNPGQGNYAAA
NAVLDALAQQRRDRGLPATSIAWGAWAGGGMADQARAGSATLDPELAITALWQLAAEGSA
TTVVADLRQPQLLHGLLSMRPSPLLAELPEAQRVLDQVENERREAASAASELQRGLRGLS
GEQRVEPVLDLVRTRAAEVLGHSGKEAVSVDKAFRDLGFDSLTAVELRNQISALTGLTLP
ASLVFDYPTPRVLAEYLLAELLGEGSMLDEPAAVAEVTDEPVVIVGLSCKFPGGVNTPED
LWQLLVEGGDAISEFPEDRGWETDWLNGDGPSSGVTGRGGFLPGVAGFDASFFGISPREA
VAMDPQQRLLLESTWEAIERAGIDPTSLRGSRTGVYVGTNGQDYQHLVMRSQDDMEGHAG
TGTSASVISGRLSYTFGFEGPAVTVDTACSSSLVALHFAAQALRSGECSLALASGVTVMT
TPSSFGGFDRQGGLAQDGRSKAFADGADGTGWSEGVGVLVVERLSDAERNGHRILAVVRG
SAINQDGASNGLTAPNGPSQQRVIRQALTSAGLQPSDVDAVEAHGTGTALGDPIEAQALL
ATYGRNRNEPLWLGSVKSNLGHTQAAAGVAGVIKMVLAMQHGVLPRTMHVTRPSSHVDWT
SGAVSLLTAPREWPEVDRPYRAGVSSFGISGTNAHVILEQAPPQAPVIEQARVEPKAVPL
PVSARGRSALDDQLDRIRAAEGNPLDIGYSLVTGRANLDQRAVLLSTEDGLTEVARGTAT
GRSLGVLFSGQGSQRIGMGRELHARFEVFADALDAVLAKLDPRVRDVMWGEDQEALNQTG
FAQPALFAVEVALYRLIESWGIKPDHLAGHSIGEVAAAHVAGVFSLDDACKLVNARASLM
QALPTGGAMIALQATEDELTLPEGVSIAAVNGPRSLVIAGDEAAAEAVASKFAKSRRLPV
SHAFHSPLMNPMLDDFRAVVAGLTFAEPRLPVVTGGDVTSPEYWVRHVRDTVRFADGITT
MTEAGVTAFLELGPDGVLTAMAAESAPDAVLVPACRKDRDEETAALTALAKLHVSGVGVD
WRPVFAGTGARRVDLPAYAFQHEDFWPVTAGARRGDVGDIGLVAAEHPLLGAAMPVAGSD
GLVFTSRIAPAALPWISEHVVNGVATFPETGFAEVAIRAADQVGCDRIEELTVTTPLVLG
ERDAVALQVWVRAADEQGRRAIEIYSRPSTSLDTWTTHATGVLGNGEQIAELPAEWPPAG
AEPVDLADWYSESEFGANFRGLKEAWISGDEVYAEVELPEDLADAAHFGLHPALLAVATQ
AVDLADVDGLDAGLSPAVWTGLSLHASGATVLRVKLKRTGRDSVSLAAADGEGAPVCSVE
SLVMRPLVAVRENTQQQDALLTVDWVPVPAELGPVPEGSRWAVVGADELGVGAAVKSAGF
DVSASAQSLVDTIAESDGVPDLILVPVTGGSDGDVPQLVRETTGRVLGIVQEYLADSRFA
RSRVLFVTRGGGDLTAAPIWGLVRTAQSENPGSFLLVDVDGEDHSLDLLPMLPALLASGE
SQVVVRDGVPKVGRLARAAEGAPAPEWNAEGTVLVTGGTGGLGAELARHLVGERGVKHLV
LTSRRGPDAPGALELRAELTAHGAEVDVVACDVADRASVDALLANISGDLTAVIHTAGVL
DDGVVGSLTPERLDTVMRPKVDGAWNLHEATKELGPAAFVLYSSVSGVLGSAGQGNYAAA
NVFLDSLARHRRELGLPATSLAWGPWTQDGGMTSGLDAGAVERMERSVTPPLSLAQGLAL
FDAATARDDAVLVPLRVRTGNARSDAPIAPILRGLVRTGRRAAGGRAGGGAGLAQRLTGM
RENERVRFVMDLVRTHAAVVLGHASADAIEPDREFRQLGFDSLTAVELRNSLAAATGAVL
PATLVFDYPTPTALAEFLVAELLGTAPDEGPSLLAELDRLESALSASDADELARAGVAAR
LRNLLAQVGGAGKAEEAAPVAERIHAASTDEVLAFIDNELGRGSADR
>A0A231GWZ6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia cerradoensis|TrEMBL
MADDIKHLDYLKRLTVELRHTRQRLREMEDRKSEPIAVVGAGCRFPGGVRSPEDLWRLVS
DGVDAIGAFPDDRGWDVDGLYDPDPEARGKSYTRSGGFLYDAAEFDAAFFGIGPREALAM
DPQQRILLETSWEALERAGIDPSTVRGSDTGVFAGAANGEYADLLHDGPVDLRGYLLTGT
TGSVVSGRVAYALGLEGPAVSVDTACSSSLVAVHLAVRALRSGECAMALAGGVTVMGSPG
MFVEFSRQRGLAPDGRCKSFAAAADGTGWSEGAGMLVLERLSDARRRGHRVWAVIRGTAI
NQDGASNGLTVPNGPAQQRVIRAALADARLSPGDVDVVEAHGTGTVLGDPIEAQALLSTY
GQGREPDRPLWLGSLKSNIGHAVAAAGVGGVLKTIMAMRHGAMPPTLHVDEPTPRVDWSA
GAVELLTERRDWPAEPDRPRRAAVSSFGISGTNAHVILEQAPTDEPAEAADAGPESIVAQ
TFPWVLSAKSEASLRAQAERLREFLIADPALSVADVAYSLVSTRAVFDHRAVILGDDHAS
MLDRLAAVAAGEPGSGIATGVAAPARVAVMFAGQGSQRTAMGQQLYQRFPAFAEAFDRIC
AQLDPLLGCSLREAIDSGADLDRTWLTQPALFAVEVALYRLLETWGVTPEVVFGHSIGEI
AAAHVAGVLNLSDACALVAARGRLMQELPSGGAMLAVQAGAAEVAELLDGLDGVDVAAVN
GPAAVVISGHAERVDELAELLRARGRRVKRLRVGHAFHSALMEPMLERFAQVVETLRFDP
PRIPVISTVTGAVADPELWCSPRYWVDQVRLPVRFADAAAAAWAQGVDTFLEVGPDAVLS
AAAADCLPDDAATVPALRADRDEPADLLAAAARLFVRGVPVRWNAVFAGRNPRQVELPTY
AFDRRHFWLETSSGPADVGAAAPAGNRDRSPETLLRIEWVAAARSTRIVDPERIAVVGWN
AANVRSYPDAAALIADLDAAADSAVPDIVLWKCPTFEGPPPLAARRVVAELLETVHLWLR
DARLTGSRLVVVTDRAVSVDASEAVNLAQAPVWGVVRAAQAEHPGRFQLLDVDHDVWEQS
ARTLAKYAFSTGEEPEVALRGEAPSVPRLRPHDAASAIPALGSGTVLVTGGTGGLGALLA
RHLVVNHGVTHLLLASRRGSVAPGAERLRDELVDLGAQVRIASCDVSDRDALSGLIGGIS
DEHPLIGVVHAAGAADNGVVETITAERLDPVFAPKVDAAWHLHELTRDRSLSLFVLVSSA
GGLVLAAGQANYAAANVFLDALAVHRRAAGLPATAIDFGLWEATGLGALLSDGDVARIRR
QGLPPLTAAEGLALFDLAIATESAQVVAARIDTAALRDRGDERPALLRDIAPATAGDRVP
ARTSGGVPADESAALDLVRSVTAEVLGHTSADEVDPRRTFQQLGVDSLGGVEVRKKLGAA
VGLHLPATLVFDYPTPQVVARFLAAELSGGVGVDESVADRPRTGDDPIAIVAMSCRYPGG
VSSPEDLWRLVADGVDTNGDLPVDRGWDIESLYDPEPGTPGKTYARTGGFLYTAADFDAE
FFGISPNEARAMDPQQRLLLETSWEALERSGVDMASLRGSSTGVFAGMSFHDYPGSANSG
SIASGRVSYAFGFEGPAVTVDTACSSSLVAMHLAAGSLRSGECDLALAGGVTVMATPETF
VEFSRQRGLSPDGRCRSFADAADGVGWAEGVGVLVLERLSDARRNGHEVLAVIAGSAVNQ
DGASNGLTAPNGPSQRRVIRQALANAGLSPADVDAVEAHGTGTTLGDPIEAQALLATYGQ
GRDPGSPLWLGSLKSNIGHAQAAAGVGGVIKMVMAMRHGVLPRTLHVDRPSTKVDWAQGN
IELLTESVSWPEVDRPRRAGVSSFGISGTNAHVILEQAPDTGSRPATTVPADAVLPWVVS
ARTGVALADQARRLASHLAARDHDPADIGFSLATRAVFDHRAVVISAERDALRAGIRALG
RGEPAPGVVSGRATPGTTGMVFSGQGAQWAGMADGLRSAYPLFAEHFDATVGELEQSLGQ
QVSLSDALADDDLADYTVFAQAGLFAFEVALYRLLESWGVRADVVAGHSIGEVAAAHVAG
VLSLEDACVLVAARGRLMQALPVGGAMVAVGASEGDVLPLLGAGVSIAAVNGPSSVVLSG
AEAAVTAVLEASAERGWRTKRLRVSHAFHSSLMEPMLSEFASAIAGLTFARPAFPLVSTV
TGRQVGDEMCDPAYWVGQVRDAVRFADAVSAMAEMGVSRFAEIGPDAVLYPMVDQTLDGR
AAPHAPAVVALAHRGRADATTVIAGVAGLFVTGAEVNWAGLYAGTGSRRIDLPTYAFQHQ
RYWVNAAPPAADGGARALGFVDTGHPLLSAMVSQPDSGAVTLSGRLSVRTQPWLADHRVM
DTVLFPGTGFVELARHAGEQVGCPALDELVLRAPLALPEIGGVAIRVAVGEPDETGHRAV
RVFSCPDGEVDSVPSWTLHAEGVVAQAGTAPDFDLISWPPAGATAVDIDGVYDALDALGY
RYGPAFRALTAVWRGDGGIYAEVAVPESVHADATGFGLHPALLDAALHAVRSASEMPTTE
IALPFEWSGVTVYAGGADSLRVRLTPEGDHGVALDLADSTGIPVATIRHLASRPIDPARL
TAGAATGRNALFEVGWTPVALPEVEATTARWAELGDDVPGLVVWDCPTGDEPGAVRAATH
DALHVLQAWTTDSRFADSVLVVRTDGAVSVAGEAITNLAGAAVGGLVRSTQTEHPGRIVL
LDTDSGVPDGVQAAGEPQIAVRAGQAYAGRLTRVTPAAAVPDDSFTADDTVLITGASGYL
GGLIARHLVTARGVRRLLLLSRRGESAPGATTLRTELENLGARVDFAACDAADREALAAA
LSAVPAGHPVTGVFHLAGVLDDGAIGSLTPGRLDAVLRPKVDAALQLHDLTRDLPLKAFV
LFGSVAATFGNAGQGNYAAANACLDALAAQRRASGRCGQSLAWGLWEAEGGMAAELDAAA
RQRIARSGVLPLAAEHGLALFDAAMRIDAATLVLARVDLDALRGAGTVPPLLADLVPQRR
TAASGAAAALRARVAGTPDHERPAVLVEIVRGQVAAILGHDHAHAVDVDKAFNELGFDSV
TAVEFRNVLKTVTGLPLPATLVFDYPTPQALAGHLVDMLTENDPSEPDTVPENEIRQALR
TIPLSRLRTAGLLDTLLELAREGDTPRAATDDTGRGVADESIDELDIDDLIDLAYNGSSE
D
>A0A221W4T4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinoalloteichus hoggarensis|TrEMBL
MTDTNGKLVEALRSSLKEIERLREQKRALVAAATEPIAIVGMACRFPGGVRTPDDLWRLV
RDGGDVLGGFPTDRGWDLDHVYDEIDGSGVRAGGFLADVADFDAEFFGISPREALAMDPQ
QRLLLEASWEVIERAGVDPVSLRGSRTGVFTGLMYSDYSSRLPSVPPELAGFVGNGSAAS
VASGRVAYSLGLEGPAVTVDTACSSSLVALHWAIQALRAGDADLAIAGGATVMFTPGVFV
EFARQQGLAGDGRCKPFAAAADGTGFAEGVGLLLVERLSDARRLGHRVLAVVAGSAVNQD
GASNGLTAPNGPSQQRVIRQALASAGVGPSEVDVVEAHGTGTRLGDPIEAQAVLATYGQG
RERPLLLGSVKSNLGHTQAAAGVAGVMKMVLAMRHGIVPPTLHADEPTREVDWSAGAVEL
ATESAAWPDTDRPRRAGVSSFGASGTNAHVILEAAPTPEPTSPPASTPDRPALTIGPPWQ
VSARSPEALTAQIEQLAALTADPTDVAHSLATTRATLDHRAVLVDGVEVARGVAGDLDVV
LLFSGQGSQVVGMGRELYGCFPVFAAALDEVLGLLGSGVREVMWGGDGEVLGLTGWAQPA
VFAVEVALCRLLEWCGVSPGVVVGHSVGEVAAAYVAGVLSLGDACVLVSERARLMQALPG
GGVMVAVEASESEVVPLLSAGVSVAAVNGVSSVVLSGVESEVVGVVSRLGGRRWSRLRVS
HAFHSSLMDPMLEGFREAIGGLSFSEPRVRWVGGGDGGSVDFWVRHVRETVRFHDYVSGL
GEGCVFVEVGPGAVLSGLVDGGVPLLRRGRSEVESFVSALARLHVAGVPVDLTRLYSGGR
RVDLPTYPFQRRRYWLDADPRARTRHAADDLRHQVGWTPWHLPASTATPGDRLIVTASRQ
DSTSLGAALGRDGAGVRTIEVAAVDRAALADQIRATLAESAVSALVSTLDLPGTIALVQA
LGDVGVSAPLWCVTTNAVATEPGEAPDPAQAAVWGFGRVAALEHPDRWGGLVDLPVGAGD
HLVGRVADVLAAGDEDQVAIRAGGILVRRLDHAGTAAPPAEPWRPSGTVLVTGGTGALGA
QVARWLSAGGADHLVLAARRGDQAPGAAALREELVGAGTRVTLAACDVSDRDALAALLDA
HPVDAVFHTAGVLDDGVIDALTPGRLDTVFAAKAEAAAHLDELTRGRDLSAFVLFSSGAA
VWGSAGQSAYAAANAYLHALAERRRAAGLPATAVAWGPWAGDGMAGGIEQDQLDRLGLLG
MAPERAIEALQRVLDLGETSVVVAEVDWARFGPAFTVVRGSRLLDRLVRPDDTAAALDYA
ALPPGESAAALRDLVLRHTAEVLGHSSPADIAPDRAFRDLGFDSLTALELRNRLGAATGL
ALPVTAVFDHPTSAALAAHLHAELVGHTEPVLDELDRLESAFAEAELDDGRRTAVAARLR
RLLDRCAAADGVGIADRLEDASDEAVFELLGKEFGIS
>A0A086Q4M0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii VAND|TrEMBL
MEQKQEDSASTSKSEVNKSLVESLSTAKGARHTDDGFIFTNGQQNLHEAKKDQHGTSDST
LAEPVSNAILDPITRVTDALLVTADGTSVHKDEEELSLVAECFACVTGVEKSCLRPDTPF
LSLGLDSLTAVELANEIQRRMKQPVEPFELFEFADLRSLALYLRNKKLDHGKDARGRQTK
SSPERSLGIVQVQRPSVFVTGVACALPGSCQTPDKLWEILDAGIDCVGPIPPNRNFCASQ
NFAVIGEPRTANASFCVTEGGFLDDVDLFDNSFFGIPDAEAMTMDPQQRLLLMKAVEALH
AAGMATIDSRSAPIATFVGCCSTDWQRMNLGEQIQSFSATSHSASMLSNRLSYTLGLTGA
SITVDTACSSSLTALHCAMQELQHRHVPCHTAVVATVNLLLTTDVTLAFARAGFLSPTYR
CKTFDDAADGFVRSEGVVVFVLQTDVSETPTPNFKNQQEDNEGGQGECGTRIPASGYLCR
ILASTVVHGGKTGSVTAPSGSSQELLYKQTFACAQVPPRAVDLVETHGTGTRLGDPIEIS
ALCNSFAPDMETRKHRLVLGALKTNLGHLEGASGLAGLLKSVLCLNRQRVPPNLHLRKLN
RFIDFRSLPVLLPTKTVPLPASSSETKDAVALVTSLGFGGTYAQVAVQVPSTTGNEMLLR
NQETVQWNKKCFDVGKLVSQSNSFQSAVSHNDTKGPCFWEVGWEFLLEFDSITLTLPTLP
EQAPPAKWLVLTSPKAQQSFRKFSVNIFLPGIRMTFACLEELKAPEHLEAILKAETWTAI
VSTYTTETGSCMTDSSDLIGRTLQILQTYGQMASQSAVLPRLLFLTQGCFQVGAAASLLR
ASPYNAGIIGFVRACRLEIESLSGRKAPIYLIDFAANGTLTETLSAVSKLLGMIDIRNVD
ETEFAICGKRVFAPRLLPLHLGLEEILPAYDHYMDLTKKADESPAGTAKFPRLVEPANKA
CRVRLLALCLDEIFPIEAISPASKAFELGESRPCTLPYGYRNRRQKPSCTKWNERSYSHR
RIRYELPLCWLNRNKANVYFNQKRLGQSTCIFIEVILKLAVRFILPACFTKKMNAAPPST
ARENRPLYSALSDLKGLAFLCCAPGPDNASSLCGCSGILLEHGADSQHLTVGNVVCGIMP
RPHCEIADIPGILLHPSPPSFSCELAASLPPQLALLLWALNQAPPLVTPPAKRVSRVLIV
GAGCGVGLVAATHFQTLGLKTFAVVCTEEQVEALVHYQFPHAAIWCYDRPDLRSALRREL
GYSSIDMVVWALKQEIDSSNNHLLNLLKHGGSFVDLVACHPESRLGWRLDVKYVHCTLDL
AARPYHAKEFSKNLALSCEILRQKTASQRQQIMHVFFDHAHRLGQHCSLASVQMTEAATP
QNVTSPADLSKQNVSFRPGVNAVEFVSGYSHAGSVVCSLPSPIFFNKASSSNGNCESNAS
TASSSAALGTEASSNVRTGTVLIFDCGSGNTWQHLRQWLSDEGASHIVVVHACAEEGADT
LGVKTLHPSRVNGGQGCSQTLIKEVKCRPHHPEEVVELFKLLKEGLHFPLVRGIFYILGE
KLDSLLANQTTSSVHDMMKTASGAWSIHHALGQLGMEADLDFFIFFSSISALFGSISQSI
SAAVHASLDALAYYRRHLGLAATSIQWAPWADGSSATSPQIVRHWLEKGGVSSVRNPLAA
VSAILKNHTAIGAVVACFHADPTIMHEMGETDQECTFLSSGPAANTRDSTSGNVKVRTNP
VKSRVFQNVSPSTDTCGENHKDELLVILTQLVRREVIEIASCYVFFEGNNLSTDESLVDL
GLDSLSAVELRHTLQQRFCVNIEPTFLQANATIDSISALLVTHVATSLTGALPVLPLSCP
GLASAVDDCALVSLALRLPGRCDSLDAFWASLQSDSGYCRPGASEACDQCFMHRAGSGEL
PAESQSIGTNLDARKGFCWLSNRDAFDSHFFGISFTEALATDPCHRLLLEATYEALCKLN
TEQQSGTSGTPIAVFATSSSTQMRASLPSYTKPASSQNTQDNNGCLAASFLSYHLNLTGL
AVPIDGSDSASLIALDLGREHLRGTDSVCQAVVVAAGSLLPICSHGWPSACTSPTIRRFR
GRDDHAFPDRETYAVPRGEGIVSVVLQRLSVARENGNSPMAILKGISLIRMGRGERPIPS
QWRTADVKLRRKTIVEALKMSRVEPRTVAVLETDGLTGSQAEDAYTVEAMADIFGPRHLA
ESCSPLVIGNASLHIGQAREASGLATLAKLVLMLERGYAPPIPRLRRLHPDVKRGILPSG
FVMFPCKKMDLLAFRQHPDHVYGPNEKRDQKEGRPLIGCVSSLGSDKTSGCFIVESSPRR
HGRTSDTRVSLERAVPLAGTKDACSHNYLHVRSTDGSESEIRGDDRAVWLFCDDLWGLQS
VGRGLYCSDPAFAALLEQAERVLGNRIPQPLSCLLYPSTTAEFQKAEDALAFPRIAAFVL
FSLQWALATCLRHQEGEPTAVMGLGVGEIAAAAVAGILSLEDAVELLELLSSETRTCDYR
NKPMPGGNVNSGGLFDRGNSGTGGCGVAQDCKSPWVLCGLNKTPTSESAALEFSVLESRR
GSSSRISSETPTSNTTPHNRDVFQERFSRKPRRATCPSPIIRHAWEKVAHGNPENDEEAE
LECPSSQSRRANCPSPAIQHACEETAHGNHANDGEADLLMDVFRFRPEPSEPLGQVTARI
ALRNATCLFISTVSGRLATDTLIRAAEYWDPLVPKTQRVHRAVETAVQVAKTAKLVCIGC
SAQDGVHLSVGLPSVHPISPSPLRIFCFTGSSPSPQLLAPCESASGSSPRVAVVEHHGAD
SNLGGGAPWWKHLLFRLPQLEGFPSGCSASTRLLADRLVADVPTPDNHMINNPQTAAVQG
AGETLGTLREGSSGEGEDGEKGYRSESVNTQHPVYKVYRRCSEPELHESELSLLCSDTVC
QPSLEKTVELFIGTGLEQQGKLSTVSSSWLVFSDIVAPSPISLYSTLAFQNEDGEQRFCT
LNVASQVATVYAEKVKTQVCSIIIECKRGFKPPREIARCHFVKNQTAVGKHEPAVSSLSR
IRWLPATKLPEGWLRTRRPHVWPCKIKVTKAACPLPTRRVDLQEIYWGKRHILCRFRMPR
NPPRDGVEKSTQLIAILARLVTVSVGVAATCVLHETETSGRYSHSHPGPQVEDDQKTHMD
ALWVCPYVPFSECWCVIRHRRNGSSIKEGKGRDWETCDVEIFSENGTAVAVVLGFGIQSH
ALSMRMMEGRGNDGDSSVSTTVCVA
>A0A100J4Y8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MASEEQLVEYLRRVTTELQDTRQQLTDHQERDREPIAIVGMACRFPGGVCSPEELWDLVA
AGKDAIEDFPTDRGWDLDTLYHPDPAHYGTSYVRHGGFVDHATDFDAEFFGISPREALAM
DPQQRLMLETSWELFERAGIDPHTLKGSRTGVYAGVSSEDYMSQLARIPEGFEGHATTGS
LTSVISGRVAYTYGLEGPAITVDTACSASLVAVHLAGQALRRRECELAVAGGVLVLSSPL
MFTEFSRQRGLAPDGRCKPFAAAADGTGFSEGVGLILLERLSDARRNGHNVLAVIRGSAV
NQDGASNGLSAPNDAAQERVIRAALADARLTADEVDAVEAHGTGTRLGDPIEAQALIAAY
GGGGRERPLLVGSLKSNIGHTHATAGVAGVIKSVMALRHGVLPATLNVEELSPHVEWGAV
EVVTEPRGWPESGRVRRVGVSSFGISGTNAHLILEEVPGGEEGASVEEPEVVPWVVSARS
SGALEEQVRRVGELEASAVEVGWSLVATRSVFEHRAVVVGGDVVSGVAGDIGPGPVLVFP
GQGSQWVGMGAQLLDESPVFAARIAECEQALAPHVGWSLAEVLRGGRELDRVDVVQPVLW
AVMVSLAAVWEGYGVRPAAVIGHSQGEIAAACVAGVLSLQDAARIVAVRSDALRQLQGRG
DMASLGVGTDQAAELIGDRPGVSVAVVNSASSTVISGPPGDIAAVVSEAEARGLRARLID
VGYASHNAQIDELREELTRRLSDVHPSAVSDVAFYSTVTAGRIDTTALDTEYWVTNLREQ
VRFAETLEALQADGYRLFIEASPHPVLVLPMEETIEAGIVVPTLRRDQGGTKQLTLAAAQ
AFTAGADINWHHWFPTPPHPIDLPTYPFQRHRYWLPDTAPRGTHATSSGHPHLSTAVTLA
DGGVVLDGRADGLKGHVVAGTPLVPGAAFVEWVLRAADEAGCAAVEELTMQAPLVLAEAG
VRVQVVVGAAGERGRRDVHVYARPEQGDVWVCHAVGEVGGEAVAPPARDAGQWPPAGAEA
VDLSGFYERVADAGYAYGPAFQGLRGVWRVGEDLVAEVELPRPAGPAAGFGIHPALLDAA
LHPLLAGWDRDGVLLPFVWSGVSLWASEATAVRVRIVHLREDAVRVTVTDPAGGPVLDVA
ELRLRPTGAEQVRAAVGADGLYELRWYPLPVTAVDDRLTWAALEELTQDASPPDLVLTTV
DTGGADELAVTEGVLSTVQEFLAAPGLERSRLVVVTRGAEGDLAGAAVWGLVRSAQSEHP
GRFVLVDTEGEEAAVVVDAVRRALAVDESQVALRAGRLVMPRWARAGVSDEVAGPSGARV
WRVVSGAAGTFDAVSAVACEEEALAAGQVRIGVHAAGVNFRDVLIALGMYPDPDAVMGTE
VAGVVAEVGPGVTWPVVGERVMGMVEGGFGPWAVADARMVAPVPDGWDMRQAAGAPAAFL
TAWYGLVEVAELRAGERVLIHAATGGVGMAAVRVARRLGAEVFATAGPGKHAVLEELGID
EAHRASSRDLAFAEKFGRVDVVLNSLTGEFIDASLQLLGAGGRFVELGKTDVREPDGVAY
TAVDLVADAGPGKLGEMLGRLGEVFASGALPVRAWPLGRVRDALRFMSRAEHTGKLVLDV
PAPVDPGGTVLITGGTGTLGGAVAEHLVRTGETARLLLVGRRGRADELVARLRDLGAHVD
VVAADVSEPGAVASLIAGIDPAHPLTGVVHAAGVLDNALVDAQDPDRLARVWAVKAGAAR
QLHEATRAKRLGMFVMFSSFAATLGTPGQANYAAANAYCDALAVSRRAQGLAGLSVAWGL
WEATSGLTGTLSAADRARIDRYGIKPTGAARGCALLDAARRHGRPDLLALDLDVRTPDAG
QVPTVLRGLTAPAARPVAASAGAVADWPVRLAALTGEERVDLMTGLVRAHAAGVLGHADA
DAVRVDTQFKELGFDSLTAVELRNRLAAATGLKLPAALVFDHPRPRALAAHLAERLVPDA
EPAPAGDATAQVLREVARVEHGLSAAVVQSLDRAAVAARLEALLAKVLDTGDGDGVDRLE
TATAQQVLDFIDNELGV
>A0A378SMJ0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium gilvum|TrEMBL
MTEDNQHPFATPVAVVGATAIYPGEPGLEGYWRTITAGRDAISEVPPSHWLIEDYYDPDP
TTPDRTYCKRGGFIDPVPFDPMRFGLPPTALPATDSAQLLALIAARKVLDEAERGGVDVD
LDRVDIVLGVASTTELVVQMGSRMQRPIWRKALLENGLPEDEADEICRDIADHYPPWLES
TFPGLLGNVVAGRVANRLDLGGSNFVVDAACASSLSALQTALHRLYLRESDLVLTGGVDA
LNDVMMYMCFSKTPAFSQSGDCRPFSDAADGTIIGEGVGMLALKRLSDAERDGNQIHAVI
RGLGSSSDGRASSVYAPRSEGQAKALRRAYEHAGYAPSTVELVEAHGTATRAGDVAEFAG
LKAVFTDDSARVALGSVKSQIGHTKAAAGAAGLIKAVLALQHSTLPGTLKVDRPNPALGL
DGTPFYVNAQTRPWVRTGDQPRRAAVSSFGFGGSNFHVTLEEYRGEHRARRLRTLPTELV
ALSAGSEAELQERAAEITAAVRAGQSLARIAFTTAPAFDASQPARAALVASDTTTLEGLA
EKLRGALADGTAAQIKDPNIAVGLGPARTGKTAFLFPGQGSQYVGMGADLALGFPEALAV
WDGLTGDLADLHRVVFPEPTFDAESLDAQKSELTAMENAQPAIAAASLAQLRLLDMLGVT
ADAAGGHSFGEVTALAAAGVLPVERLVETARMRGVLMAEAGQGTDGAMLAIVAGADDVRA
LLNSRPDTVGTLVIANDNAPNQVVVAGHAADIAWAETTAKAAGFSSRRLPVASAFHSEIV
ASSSAPLGKYLETLTLGESRFPVYANTTAQPYGPQIVDQLADQVRQPVRFREMIEAMARD
GVTRFIEVGPGRVLTGLVDQILDTTPHLAVTLDGSKSDGLRGWHRGLAALAADGLQLDLA
ALYAHFDEPAEHVPAPAHSVLVGGANLGKPYPPVDGITAIVPKRVRATAPISPPQAEKAS
AEGLPMTPAVQQMEAPAIQPVAVPAAEVHVSTPAHQPAARVSPTPEVHVPVSAEPAPLSV
DAWSVIDRIQKETAEQHQRYLDVMTQSHQAFLDVATQMMTEIVGGRPTGPQAPRLALKEV
VSAPDTAVNGVAPAAHTPAVAAVAPEPAMAPAAPAAPMPLAPAAPEMAAPSAPAPAPAAP
ALPVGDIVLSIVSEKTGYPADMLSLDMEMEAELGIDSIKQVEILAALQAKYPGAPDIPAS
ELAGLRTLQDVVDTATGFTTTTTTTAPAAPAPAPAPAAPALPVGDIVLSIVSEKTGYPAD
MLSLDMEMEAELGIDSIKQVEILAALQAKYPGAPDIPASELAGLRTLQDVVDTVSGFSAR
PAGDDLDPEPAPAQPDSPSGGLSCTEAELRAVPPGGFAMAGLRDGEVFITREDPEFADSL
ETVMIDRGIKAKAVDEVPERAGAVISLAALASVESPQGCVDMHVRAFHAARSVARSDAES
RLFVTVQSSGATFGAAEAPTGVASLVKTAAWEWPNASVRAVDMETLDAERLVAELLEGGS
GVEVALCADGTRLVAVADVASTVGEGENIGVDPGGVVVVTGGARGVTAASALALARHHGL
RLALLGRTPLRDVTAAESAGTTAAEIATSLAAAARARGEQLSLPQARAQAESVLAEREVR
ATLAAAEKQGIPARYFSAGITDRAALTAALDEVRHFGAIVGVVHGAGVLADKRLEDLDDE
QFVKVFSTKLVGAEALLEATSGDDLRFVSLFSSIAARAGNPGQAAYAAANAALESIAARE
AARRGDSCVVRAFGWGPWDGGMVDATLKSRFLEAGVGVIPIDDGARFFAEHALRRSPATS
IVVAAPAEPRLRAAHLEWDVSVETLPVLEDHQVRGQIVIPVVAVLDAVLRAARGLIADSA
VVVRDLQVLSGVTFASCEQQDLTIDFEPTGASYTVTVKDCEGRARYRAVLETSSAAPSTS
IPSIAGSAWPMSVADAYSGPLFHGPRFAVIDELGEFAAAGGSATLKSATELGWPQQDWVI
DPVAVDGGLQLGILWANAHGHPLVLPVRIGSVTVHRPFADGDARRCRIAAHPVNDKRVDF
DIALETVDGQPVATLEGVEFYVAGTGS
>A0A291SL81|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces malaysiensis|TrEMBL
MTAPDEQIVDALRASLKENMRLQQENQRLSESSAEPIAIVSMACRYAGGIRNPEDLWRVV
NDGTDVYTSFPENRGWDLEGIYHPDPDNPGTTYVREGAFLHDANLFDAGLFGISPLEALA
MEPQQRQLLEICWEALERAGIDPHSVRGADIGVYAGLVHQDYAPDLSGLEGYLSLERALG
SAGGIASGRVAYTLGLEGPAVTVDTMCSSTLVAVHVATQALRRGECAMALAGGATVMSTP
GGFIGFARQRALAFDGRCKSYGAAADGSSWAEGAGVVLLERLSDARRNGHRVLAVIRGSA
LNQDGASNGLTAPNGPAQRRVIRKALENAGLTTADIDMVEGHGTGTVLGDPIEAQALIAT
YGQDRPEGRPLWLGSVKSVIGHTQSGSGVAGLINAVQALRHGVMPATRHVDAPNPQVDWS
AGAVELLTEARAWPELGRPRRAGVSSFGASGTNAHMILEQAPEEPAAESPSGPALDGVVP
LVLSAATAASLTGQAQRLGSFLEASGTVALADVAAALVTGRASLAQRAVVVTDSPEEALA
GLGAVARGEDVRGVVVGGGVRSGGDGKVVLVFPGQGSPWVGMGRELLECSEVFAARVGEC
AVALERWVDWSLVDVLRGDCPVEFFEREDVRQPASFAVMVGLAAVWESVGVVADAVVGHS
GGEVAAACVSGALSLEDAVRVVAVRSKTISGVLSGRGGMASVGLSEEEAVARLQQWDGRV
EIGAVNSPSSVAITADTEALDEAIETLEDQGVRVRRIAIDYASHSRHVGAVQEILNEAFA
DIRSQAPTVPFLSTATGEWIREAGALDGGYWYRNLRSQVRFGPAIADLLAGGHTVFVESS
AHPVLVQPISEVVADAEAEAVVTGSLRRHEGGPRRLFTSMADLFVRGTHVDWSGVLAAGA
DARRVDLPTYAFDHKNYWMELAGTANDVASLGLSGADHPLLGAVVPVPETSGVLCTSRLS
LRTHPWLADHAVGGVVLVPGTALVELVVRAGDEVGCGTLEELVIETPLVVPAQGSMRVQV
AVGGPDENGARSVAVYSARDDDGRGTGIDGWTRHAAGTLTAAAVPADGFDFTVWPPVGAE
RVSFDAVGFYEEMAGRGYVYGPAFQGLRGVWRRGEEVFAEVALPDEQHGEASRFGLHPAL
LDAALQSGLVRPADAGVDMRVPFAWNGLRLHAAGASELRVRTVPSGPDAVSLQAADGAGG
PVLSLESLVARAVDVEQLDRMATDDGRDALFEVDWSELPAPASSVESLPPSALVASAEDV
TDLADAAVVPAVAVLEAVGGDGEHDALALTVRVLEVVQAWFAAAGLAESRLVVVTRGAVP
VGGEGNVADPAGAAVWGLVRAAQAENPDRIVLLDLAADVDMGSVLPAVLAADEPQVAVRG
TTLSVPRLVPAGKRALQIPEAGEWRLGVGTTGVGTLDSLSLLPEPRVTTPLAAGQVRVGL
RALGLNFRDVLIALGMYPGAAELGGEGAGVVLEVGEGVTELAVGDRVMGLTGIGYGSMTV
TDHRCLVRIPQGWSFQQAATVPVVFLTAYYGLRDLGGLRAGESVLIHAAAGGVGMAATQL
ARHLGARVFGTASPGKWGVLRELGFDDAGIASSRTAEFEGHFLTGTSGAGMDVVLDCLAG
ELVDASLRLLPRGGRFIEMGKTDIRDAGVVASEHPGVAYQAFDVFDAGLDRIQQMLVELA
RLFETGDLTPLPFAAWDVRRAPDAFRHMSQARHTGKMVLSVPEPLDLEGTVVLTGGTGSL
GAVVARHLVGEHGVRHLVLASRRGPDAEGARELVAELGEAGATVTAVACDVTNRDALAEL
LAALPAEHPLTGVVHTAGVLDDGVIGTLTPERVAAVFAPKVTAVRHLDALTRGMDLSMFA
VFSSAAGVFGSAGQGNYGAANAFLDGWMAKRRAEGLPGIAMAWGLWEQTTGMTANLSQAD
QARMSRGGLLPIGVAEGMRLFDTALRMPTALAVPIKLDLRGMRADAAAGGSVLALLRALV
QTGRRQAQAGENGSGLTARLASLTPQEQEKLLLDVVLTQAATVLGYTEISNVEAHKAFNE
AGFDSLTSVELRNRLREATGLKLAATSVFDYPTPLALARHLHDGLKPAQSPTGTHPLLAE
LSKLEARLVETPVDDSIRAQVTTRLQVLLTTWSTANGTPTGDEALDFDATSDDDLFDLID
TTFSN
>A0A0U0S7G1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MVALASNTRERMSSPVRNNVSKNVALLADGISDVVVICIPTLTVLSDQREYRDIANAMTG
RHSVYSLTLPGFDSSDALPQNADMIVETVSNAIIDVVGGSCRFVLSGYSSGGVLAYALCS
HLSVKHQRNPLGVALIDTYLPSQIANPSMNEGFSPNDTGKGLSREVIRVARMLNRLTATR
LTAAATYAAIFQAWEPGRSMAPVLNIVAKDRIATVENLREERINRWRTAAAEAAYSVAEV
PGDHFGMMSTSSEAIATEIHDWISGLVRGPHP
>A0A045K097|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MSDNDPVVIVGLAIEAPGGVETADDYWTLLSEQREGLGPFPTDRGWALRELFDGSRRNGF
KPIHNLGGFLSSATTFDPEFFRISPREATAMDPQQRVGLRVAWRTLENSGINPDDLAGHD
VGCYVGASALEYGPALTEFSHHSGHLITGTSLGVISGRIAYTLDLAGPALTVDTSCSSAL
AAFHTAVQAIRAGDCDLALAGGVCVMGTPGYFVEFSKQHALSDDGHCRPYSAHASGTAWA
EGAAMFLLQRRSRATADRRRVLAEVRASCLNSDGLSDGLTAPSGDAQTRLLRRAIAQAAV
VPADVGMVEGHGTATRLGDRTELRSLAASYGTAPAGRGPLLGSVKSNIGHAQAAAGGLGL
VKVILAAQHAAIPPTLHVDEPSREIDWEKQGLRLADKLTPWRAVDGWRTAAVSAFGMSGT
NSHVIVSMPDTVSAPERGPECGEV
>A0A853SAK8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Janthinobacterium lividum|TrEMBL
MEATVREVLAIDRADTIEHTRALQKMGMDSLLSVELRNRFAAELQLQLPVSLMFDAPTIA
AVSRLLMDELRTHHGKSAQVENPPTRAQADAPLRQATPSMVVNDNAIAIIGLSCRMPDGA
DGIDAFWQKLIGGFDLVRPFDGSRWDVQRFYSMGSTEEGKMYANDGGQLADVHGFDNRFF
GISDREAEYIDPQQRIALEVAWETIESAAYTPQDLAASAGIFIGPGPSDFADLSQRHAKA
LTGLMGPGHHISAIPGRIAYQLNWQGPCMAIDTACSSSLVAVHVAAQHLRQGECRVALAG
GVNLILAPANNIILSKAGMLSPSGRCRSFDAAADGFVRSDGCGMVLLKRLADAVADGDVI
WGVIRGGAVNQNGQGQGITAPSSRQQAALIETALARSDTHPSAVRYVEAHGAGTQLGDPI
EMAALKQTYGVHHDERNPLFVGAVKSNIGHGESAAGVTGLLKVLLMMKHRMIPPTLHLKA
LNPHLSIDPQTIRIPTAVQPLTLGESGELVCAVSSFGFSGTNAHLIVAAYEDRTVRPEHR
SGGIFAMSAQTRPALVALGQRYIEFLQQLPVSEDDSLGDICYSTLVGRGRFEHSLCLYPR
DRDDLLAQLQALSTAALDLPPAIEQVAVRFVAGDAPPTVGSLPWRGHRCFTEALEEAHAA
LHVQTGLLPGHEGPELAWFCLHYATARCLSDLGVQPDRILYRDSMWLVGAAVWGGTALTD
AIGSLLRGAPPAPLQLGGLPLERVADYGALLCVRDSAGVSSNFLDAAVGLDEQAWQRALG
TLWAGGRAVDWAVYFKQEGYRRHVLPTYPFEHRDCSRPQGLVGGERSIQRLIDELLTE
>K9XYL3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Stanieria cyanosphaera (strain ATCC 29371 / PCC 7437)|TrEMBL
MGGIKERSRLSKQYTFVEVLAERVAKQPEQTAFTFLQDGETELDSLTYQQLEQQARAIAF
RLQENHAQGKRALLLYQPGLEFISAFLGCLYAGVIAVPAYPPRANRSIERLLAIVTDAEA
TFALTTQALQEKIETKFQENNQTEIQFIATDTIEIQLASNWRKPNLTEDTLAFLQYTSGS
TGNPKGVMVSHSNIIANSLSINRCFQNTPEHIGVSWLPPYHDMGLIGCILQPIYVGVSMY
MMAPVSFLQRPYRWLQAISKYRANTSGGPNFAYDLCVSQITPEQRDTLDLSCWELAFSGA
EPVRAETIEQFSKYFSSCGFKQAAFYPCYGMAESTLLITGGNKQAEPVLKSFDKLAIEEN
RAVAPTDSEMATALVGCGQNIQQQQLILVNTDTFTQCSEGEIGEIWVNSASVAQGYWRNR
ELTETIFQASLATGEKPWLRTGDLGFLQAGELFVTGRLKDLIIIRGRNYYPQDIELTVDN
AHPAVRAGNSAAFAVEIEGEEKLVIVQEIERSYLRKLNVTAVTKAIRKAVTEQHELNPYA
IVLLKTGSIPKTSSGKIQRHACKAGFLEGSLQVVGEWQSGRREQPFARMHSSVYQLPVAS
QKQISIQNWLVENIAQRLGVDVSEIDIQEPFATLGLDSVQAVRLSADLEDWLEVKLSPTV
IYDYPNIISLASYLVQEEQEEIDVENINQKLINSDIAIVGMGCRFPGANNPQEFWQLLRD
GKDAISKVKGRWQGEDWGGFIENVDQFDPQFFGITPRETQRMDPQQRLLLEVSWEALENA
GIASEQLTGSATGIFIGISSSDYSQLQLHYGTEIDAYAGTGNAHSIAANRLSYSLDLRGP
SLTLDTACSSSLVAVHLACQSLKQGECQVAIAGGVNLMLSPELTETFSLAGMMAGDGRCK
TFDAEADGYVRGEGCGVIILKRLEEARRDRDNILAVIKGSAINQDGKSNGLTAPNGLAQQ
AVIRQALINAGVQAGDISYVEAHGTGTKLGDPIEVNSLKNVLMQGRKENQTCYLGSVKTN
IGHLEAAAGIAGLIKTVLCLQNQVIPANLHFNQLNPHINLAQTPIQIPNDLQPWQVEDKP
RLAGVSSFGFGGTNAHVILQEADKQTQNSELIERPLHLFTISAKNELALQELVGNYAKFL
QNNSDISLADFCYTANTGRTHFEHRLALVTESKDDLINKLINFQTDNKITRLNYSLVDKN
NRTKIAFLFTGQGSQYIGMGYQLYQTQPTFRQALDRCDQILQPYLEKSLIEVLYPNNVEI
IDELSLQDLHKTAYTQPAIFAVEYALAQLWLSWGIQPDLVMGHSVGEYVAAVIAGIFSLE
DGLQLIAERGRLMQALPQQGAMYAVFANESIVQSVIEGYSEQVSIAAINSPQNIVISGEE
TALQQIISKLESQGINSKKLNVSHAFHSPLMQPILADFAKVAEKVTYSLPQIQIISNVTG
KIITEEITTAQYWINHVIEPVKFAQGMQSLEQEKSQILLEVGAKPILLGMGRQCVTKTQG
LWLPSLRPRKQDWQQILHNLAELYSQGLKINWQEFDQDYSRQKVALPTYPFQRQSYWLER
KNQNNIVNTARKLLPIQNNKIDFYKINWQQLNINDLTITAKTWIIWTENQELGTKVAQQF
QAKQQQCLLVNEQESLEKIVDCFRQNQQIAGIIYLDDLVDHQEQLTDRVIITHYQKHCQS
ILSLVQELFKQSITTSIWLVTKGSQNINEPINQSAIISSCLWGLGKAIASEHPEYWGGLV
DLSNNFSTEEIDSLITAINYSEKEDYLAIRNKQIYVARLQELELSKQSLKINSDSYLITG
GLGALGLKLAQWLGDKGAKNLILVGRNKPSLAAQEIINKLETKGTKVQVIQADITNLEAV
NQIIAQYPSLKGIIHAAGVLNDGLLQNQTWERFEQVITPKTIGAWNLHQATQHLDLDFFV
LFSSVASLIGSPGQGNYAVANASLDAIALVRQAQGLPALSINWGPWANSGMAAAKGFNRQ
GLHLIEPQSGLAVLEQLLSSKINHAQIGVLSVDWQELSQQFPPLKQSNFFAELISLEETA
ASSAKVQVFDDLLAIEPEKRTEYLTNYLQGAIAKILQVDPNQLATTDSLLDLGMDSLMLM
EAINQLKGDLQLMLYPREFYERPRIDHLAGYLAAEFTKTHDKSVGANRGSLLHNHHSVSD
LLNQNKKSNHTKKSVSLQPPLSSPIAFILSSPRAGSTLLRVMLAGHPQLCSPPELHLLPF
DTMSEREQELGISQLGEGLKRAFMSLKGIDAQASQELVANLIKENLSVRDVYQLLQQLAG
DRDRRERTSRSAPRQGRDRILVDKSPTYANNQETLAKAEALFTNAKYIHLVRHPYAMIES
FARMRMDKLIGAGDSNPYHVAESIWSNSNQNILDLKTRIGSDRYFLVHYEELVAQPEKVM
REVCDFLAIPFDPGVLNPYQGERMTDGVNNAGMSVGDPNFLNHKQIDANLANAWREIRLP
IVLDTLTQTIARQLNYELLEEEINSTAHQEMREISINVRGLRICLCSWGPEEGPLVVCLH
GILEQGAAWSEVAIRLAQKGYRVIAPDLRGHGRSDHVGKGGSYNLLDFLADIDAIVENLA
DRAFTLVGHSLGSVVAAIFASIRPQQINNLVLVETILPSEVAEEQTAEQLATHLDYLASP
PEHPVFPNVEAAAERLRQGTPAISKALAMLLAERITEPCEGGVRWRWAALLRTRAGVGYN
GIERSRYLGLLKRIKAPITLVYGDKSNFNRQEDLSAQQIAMPDAEKVVIPGGHNLPLEAP
SALAKIISSAVALTNKLIP
>A0A378UXP6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium fortuitum|TrEMBL
MDETQSNSNLPDGTEPAAAPASRPDLTVAEMREWLRKAVANATGQSADAIDESTPLIELG
LSSRDAVAMASDIEDLTGVTLTATVLFRHPTIESLATVIIEGEPEPESTDDEDWTRDRDV
EDIAIVGVATRFPGDLNTPDEMWDALLAGKDCITDLPEGRWEEFLSEPRIAERVAKARTR
GGYLSDIKGFDSEFFALSKMEADNIDPQQRMALELTWEALEHARIPASSLRGGSVAVYIG
SSNNDYSYLSLADPTVTHPYAITGNQTAIIANRVSYFYDFRGPSVSVDTACSSSLVAAHQ
GVQALRSGEADVAIVGGVNALITPLVTIGFDEVGGVLASDGRIKSFSSDADGYARSEGGG
MLVLKRVSDARRDGDQILAVIAGSAVNHDGRSNGLLAPNPDAQEEVLRRAYKDAGINPRS
VDYIEAHGTGTILGDPIEADALGRVVGRGRDADKPALLGAVKSNVGHLESAAGAASLAKM
TLSLANDKLPPSINYAGPNPYIDFDKEHLKVNDTVSDWPRYSGHAIAGVSGFGFGGANAH
LVLREVLPSDLVEPQPEPEAVEGKSASDEANAVYVGGVRMDEYGEFIHDDDESGAGDGEY
PAYDETNHELPGLTDEAKRLIEEARAQLEAADAAEPVKKVVPLAVSAFLTSRKKIAAAEL
ADWIDSEEGRASSLESIGRSLSRRNHGRSRAIVLAHDHDEAIKGLRAVAEGKQHPSVISA
DGPVTNGPVWVLAGFGAQHRKMGKELYLREPVFAEWINKVDAHIQDERGYSVVELILDDA
IDYTNETCEYPIEVVQTVIFAIQVALGEFLKAHGAKPGAVVGQSLGEAAAAYFSGGLSLA
DATRTICSRAHLMGEGEAMLFGEYIRLMALVEYSADEIKTVFADYPGLEVCVYAAPTQTV
IGGPPEQIDAIIARAEAEGKFARKLQTKGASHTQQMDPLLGELSAEIQGIEALPLQTAYF
STVHEGKFIRAGSEPIHDVEYWKKGLRHSVYFTHGIRNAVDNGHTTFLELAPNPVALMQV
GLTTASAGLHDAQLIATLARKQDEVTSMVTAMAHLFVHGHDLDLRTLFPRKSTGLAGALD
FANIPPTKFKRKPHWLEAHFTGDSSAVMPGNHVATPDGKHVWEFVSKGTADLAALVKAAA
AQVLPDARLTASEQRAVPAEGARLVTTLTRHPGGASVQVHARIDESFTLVYDAIVTRGGA
ATTLPTAVGAGVVAEQVSAAPVQAEPEAEDDAEILSDNLTKGAGMGAGFEKWSPDSGETV
AQRLGTIVGAAMGYEPEDLPWEVPLIELGLDSLMAVRIKNRVEYDFDLPPIQLTAVRDAN
LYNVEELIKYAIEHRDEVDQIAESQKGKSAEEIAAEQSELLGGASTVAELEAKLAESGHP
LADKAAEETGPDPAAEAAATEGLEIPPPPTDPSGPAVPPPPSDPSGPSKATAAAAAAKVL
TQEAVTEALGADVPPRDAAERVTFATWAIVTGKSPGGIFNELPFVDVETATKLSERLSER
AEGTVTVEQVRSAKTIEELSTIVRDQLEEGVVDGFVRTLRAPKEGSSHVPLFVFHPAGGS
TVVYEPLMKRLPADTPVYGIERVEGSIEERAAEYVPKLLEMHKGPFVLAGWSLGGALAYA
CAIGLKQAGADVRFVGLIDCVRPGEPIDQSQAGMRARWDRYARFAERTFNVEVPEIPYEE
LEKLDDEGQVKFVLEVVAQSGVQIPGGIIEHQRTSYLDNRALDTIEIQPYDGHVTLYMAD
RYHDDAIVFEPAYATRQPDGGWGDYASDLEVVHIGGEHIQAIDEPYIAKVGAHMSEAINR
IEAESESK
>A0A7D3VRA1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinomadura verrucosospora|TrEMBL
MAADRDTAADGTGARAVQDGPERRTSATGPGTEIVGVTPFGRPAPHLAVAVARAGGHGVL
DLGTEREPALAALADVRRWWAGRFGVRVPAGCRVRPQELPDAVGTVVFDAPALLADDSLD
IAGFARGRRLLVEVVDAAEAAAVLPVAGGFPGTRGTALIARGREAGGRVGDLTTFVLLQR
LLADEAVDVPVLAAGGIGPRTAAAAVAGGAAGVVLDVQLALVREMDLPADVAAALTAMDG
SETRVVHGHRVYTRPDLPDIALADLTPAEVNARLGATGLRSRLLPAGQDAPLAAALAARH
RTAGGVVQAVREGIAEHLRAAVQAAPLASRQTPDGPEYPVVQGPMTQVSDRSAFAAAVAQ
EGGVPFLALALMDGDRVRTLLRETADRLAGRPWGVGVLGFAPPEVREAQLDAVREAAPPY
AIVSGGRPAQAASLEDAGVSAYLHVPSPDLLERFLAEGARKFVFEGQECGGHVGPRASFP
LWEAQAERLMAFGGDPAELSVMFAGGIHDARSAAMVAALAGPLAERGADVRVLMGTAYLF
TTEAVAAGAILPGFQKAAVDCGATALLETSPGHATRCARTPYVEQFTEARRELEAAGTPR
QDMWRQLERLNLGRLRIASKGLRRSTPVGPDEQRAEGLYMIGDVAALRSSTTTVAALHDE
VTDGATALLAARAADLGIAGDRAAASPAARPADIAIVGVGCVFPGARDADAYWANIVGGV
DSVTEVPAERWDPAVHYDPSEPGKTPSKWGGFLPDVPFDALAYGIPPNALGSVEPIQLLA
LEVAARALKDAGYADRPFDRSRTSVFFGAEGGNELATAYGLRAALPSYYGEVPPGLDEQL
PEPTEDSFPGVLTNVIAGRIANRLDLGGANYTVDAACAASLAALDAACKELAAGGSDMVL
CGGADVHNGIQDYLMFSAVRALSPTGRCAPFDAAADGIALGEGVACVVLKRLADAERDGD
RVYAVVKSVAGSSDGRSLGLTAPRAEGQRLALDRAYERAGVRPSDVGLVEAHGTGTEVGD
RTELATLTDAFSAAAPGSVALGSVKSQIGHTKCAAGLAGLIKTAYALHTGVLPGTLHLTS
PNPAWKPDGPFAFGTTARPWAARPGDRYAGVSGFGFGGANFHAVLAGYDGGPEPVSGLAE
WPAELFLIRGADRTAARAEIARLRRLLDVPSVRLRDIARTCASTEGRVQVAVVATGPGDL
RGKLAAAAEFRTAPGVHVRRSGDPGQVAFLFPGQGSQRPGMLAGLFVAFPRLQRLLRLAG
GRYAPAMFPPAAFGPDDARRQREALTDTRVAQPALGIAGLAVHRLLTAVGVHPDLAAGHS
YGELVALCAAGVFDDTDMIELSAARAEAILAAAGADPGAMAAVSAPLRQVRDAVSGVSEI
VVANHNAPDQVVVSGTTAGVARALAVLAERGLAAERIPVACAFHSPLVAAASGTLRTALT
GRDLRSPAFPVWSNTTAAPYDSDPADLAATLAGQIAAPVRFVEQIEAMYEAGARTFVEAG
PGRVLTGLTRRILGDRPHTAVACDAADGGSVERLLHALAELAAAGVAVDPLPLFAGRDAR
VLDPASAPAAPGWIVNGHLVRTADGGYPAGALRPAERIPGTAAPARPAGSDAAVLEYLRA
GRELIAAQREVILRHLGAAPAAPSAPAPVPAPRPVLPGETLSALPAAAEPPRDVHATVLA
VISARTGYPESMLDADLDLEADLSIDSIKRTVIIGEVTERVGLTAPDAVIEQLTRITTIG
GIVDWLRTRLPSAQGPQRPAVPPQASPRPGPSTHAGGPPAPRRQVSAPADQEGDAPKPSP
KRTAAPASAGEQSGTTPEQPTTASAGGTGRRDLEASDAEGTRAAISHRKAEADGGRPAAR
SAAPVAEPPAGAGRGSGGAGGLDPEAVPDAGAARTKAEASDRRAEGDGGRSDARSAGERT
PSGDRKRGPEASSSDAASRNAARVPSGEGDEGRRAAAPAGSAEEAPAAPGTEEPAGRAAV
PPARVPDGEEAAAGGEAAAVEVVRLAGDGAAALGGEDAQRPAPAPAGRDGETTGARRVLA
GRVRPSGERARRVVRQVVRTADLEALPVPADTGTAFDGRTFVVVDDGCGVALELADRLER
YGARVRTPMDVDGPCDGLVHLAALRPGATAVLPDAYAGIRDALAGGLRWLVVASGAGGTF
GRAFDGGGIGDPGPGAGLRGLAATVAQEYPDALVRAVDVDTKDTPRAIASRLLAELLDAR
GPVAVGHEGDLRRTTRLVPAELRGEARVPLDADGVVLLTGGARGVTARTALELARTTGCH
IEVMGRTLEPVGPPSFPDVPDEAGLRRALVAQGGRRPAEIEATVRRIVAEREIRANLDAL
KEHAASVRYHAGDVREPRLVRDVVERVYLRHGRLDGVVHGAGVVEDRLVRDKEPQSFERV
YRTKVDGASALAAAVRPDVGFFVVFGSVAGVHGNRGQADYAAANEACDTLAHVWRTRLRG
RVLVADWGPWAGGGMVSPELAREYGRRGIGLIDPDAGVAALLREIAHGDETQVVLTGTVR
>A0A7D3VRT6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinomadura verrucosospora|TrEMBL
MTAGFDLAAGFEPVAVVGLAGRFPGAADVSEFWANIASGTDCITRLSDDELIAAGVGRAS
LRDPSYVKAAPVIAGGAEGFDAELFQMTPRDATVCDPQLRLFLETSHAALENAGYDPWAV
PGAVGVFGATSPCRYVDTNVLADPAYSLDMGVDVLTNADYLATFTSYKLGLRGPSMTVLS
ACSSSLVAVHTACQSLASGESDVALAGGANIMYPYRTGYRWVPGGVQSPDGRCRPFDAAA
AGTVFGDGAGVVVLKRLRDALVAGDSVRAVIRGTAVNNDGADKLSFSAPSLVGQSGAVFE
AMSVAGLGPADIDYVEAHGTGTPLGDPIEVAALAEAYRLLGGEAAAESIALGSVKSNIGH
LVAAAGIAGLIKTVLALEHERIPATAHFREPNPALDLDATPFRIADRTREWPARPALVGA
AATAGPPPAAEPVGPPRRAGVSSLGVGGTNAHVVVEAAPAPVPIATPARPRIVVWSALAP
EAERSARGRLAGHFAALAGDVASGGARPASADTGRFADAVATLQRGRTAHPVRGAVVSAD
AAHAAHALDSGAVVTGNAGDRRPLVFAFPGQGAAKARMAAGLYGTQRVFTEELDACLDSF
EKHGSRLYDAWLDPDGDERVQETLRAQPLLFSVEYALARTWLAWGIEPGAVVGHSLGEVA
AATVAGVFDLDDAVAFVAARAAAMQRAPRGAMVALRASEDEVRAVLPPDLVVAAVNAPDE
VVVAGTDEAVRAFGTGGFPGRTLRTSHAFHSPAMDGAVSEVRQALDGVRLRPPALPLWSA
ATGGLLGADEATDPDFWAGQIRTPVRFADAAAALLADGPLTLLEVGPGQTLGRLIQRARP
GLDLSVLASLPRSEPEAAEEAHLLGVLARLWTTGHDVGWDEMEPDRPLRRVAVPGYPYQR
VRHWVDAPGTEPPPGRAAVTAPEGGTPEDTAAAEPAAAPSADRTPSPVAAVTERTWRDAP
RSARPAGTVPRLRTLALLPADPSTAVSVVAALHSSGHDVIRVRPGSAFAVHGGPAGAEYA
DYNEYAEYTVRPGSPDDMARVVGDMAARGVRAEVLVHAWATMPWPPLTSANAGAAGDLGL
HGLRVLLQEGLRGAGEASVRRLVLLTSGAVNVSGADEVDAAKAALAGAVPSLAAELPQLD
CRLVDLAGRAAFDELADELRVPGPVVVALRGSRRWVPAAIPWRAFDDEARHGEAAGLRGR
GVYLVTGGLGGLGIQVALGLARTGLRPCLALLGRGLPSGEAESAIREMTALGASVQVVRC
DVADPAAVRTALAEVTRAAGPVNGVFHLAGVPGGGVLQRRDRDQVDAVLRPKVTGTLVLF
EALADAALDFFVSFSSQAAISGSVGNADYGAANAALDALTAFHTPGPRGRRLSVNWPAWA
WTGMAADLLASGVDVDGTQGGALGRPTRPPAAEAPKPDDGPAPGPVVTVESAAAAETSWA
LDEHRIDGVPIMPGTGHLDLVVRTYRERLLGTVRAPVVLEDVVFAQPMTAERPRTIVLTL
VPAGAGAHRFTLGSRPADDDAAPLVQHAAGGIAPWDGAFDRRPADELRAGFQERVPGANR
PSNGGPRGLMFGPRWMSIREKWVRRGEVLAELALPAPFLGDTAHHDLHPALLDLATGMAA
HFGTDDLHLPFHYRRLTVPGKLPPAVLAHVRGRQEPSGVVADIEVLAPDGSVVAKAEGFR
MRRAEPGAATARASHVPALADEREAVPAPDAGRAPATSVPRRAADDVPEAGIAPRDGVAI
LLRLLADRTPPQLAVRPQLAGRPVPLPPGMAAPEAPDPASTTPASTAWSEEAPAPPRSEP
APAAAEPAAVPATGADDGAAPSEQTLRDRLADIWRLTLGRSEISPDDDFFALGGDSLSAI
QLIGRLRDLFGVTIGVGTVFDHPTLAALAVEIGREME
>A0A0J6VMQ6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium chlorophenolicum|TrEMBL
MVSVEGRSDPVARFAVVGYAARFPGAPDADAYWDLLREGRDAISEVPPDRWDAEAFFDAD
PGTPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRQLDPQHRLLLETAWHAVEHAGIAPST
LAGTDTGVFVGLATHDYLGMASDELTYSEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV
DTACSSSLVAIHQACQALRLGECDLALAGGANVLLTPATMITFSHAHMLAPDGRCKTFDA
AADGYVRGEGCGIIVIKRLEDALRDGDHIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
AALDRAGLDPRDVDYLEAHGTGTSLGDPIEAQAAGAALGDGREPDRPLLIGSAKTNIGHL
EAAAGIAGVIKVILSLEHETLPKHLNFENPSPHIPWDRLPVEVVKETMPWTRDARPRIAG
VSSFGFAGTNAHVVLEEAPATVAEDVAEPSAPVLRVLPLSARTPTALRTLAGRYRDWLTE
HPEATPADVCFTAGVARAHAEHRAALVIDSRESALDLLGALADDRPSPGLVRGESYEAPK
TAWLFTGQGSQYPGMARGLYDTEPVFAETLDACAAAVADLLEKPLLDVIFDNDDAEALRL
TSYAQPALFAVEMGLARLWQSWGLEPDVVLGHSVGQYTAACVAGVFDLADGARLMAERGR
LFAGLPAGGRMVAVFAPAERVEAVTDDVPSVSVAAYNGANTVLSGPATDLERAVAGLVAD
GVRCDWLETSHAFHSALLDPILDEFESTANRFTFGPPQRILIDNRTGAALGRSVTLDGAY
WRRHARQPVQFASSVRTLAELNCKLLVEIGPRPVLTAAALAAWPDPATSPRVIASLRPTA
TDQRQITEALADAYVLGHLPDFRAVRPSTARTLDLPTYPFEHRQYWFRDAREPVERQQRT
GPRTAAVGLLEDGRIDELAALLGATEDDTRTREILSTLAAQHNQQRDAQSITEDRYEIRW
DPAGAAPHDTADTPSWILVGDDTPATRPLIDLLTARGHRYQILGLPLSDAEEAAVADAVR
SAAAADPALRIVHIAGLDADASTSTRSLLRMQHRVLPGTRRLFRAAATAEVRSPIWLVTR
GAQRVADGDVTAPDQACLWGFGRAAALEAPQLWGGLADLAAGTAEEWSALVQRITTPAGP
GIRDDQLALRGHDGYVPRLTRRTGQPIAQGLQMRSEATYLVTGGLGAIGLEIAGHLAAHG
ARHLVLTSRREPGEAARQRIAALTEQHGCEVRVVAADVADAHDVARLLAMMHAELPPLAG
VVHAAGEIGTTPMTDLTDDEIDRVFAGKVWGAWHLAEAAAELNLDFFVSTSSIASVWGGF
GQTAYGAANAFLDGLSWRLRERGVAGSAVNFGPWAVGMADARSRARLEERGVATLSPADA
LAGLADAMATGAPQAVVARIDWARFLPLYEQTGRRGLLAELNQELPQAVPAPTATGRTAL
VERLTEAPVQQRRTLLIDYLRDAVAEVTRVDATEIREDAGFFDIGMDSLMAVELRRRIET
GVGRDIPATLAMDHPRLSDVADYLLGEVLGLTEAAPTRPATVVTARTDDPIAIVAVSCRF
PGAPNPEAFWDVLAGGVDAIREVPEDRFDIDEFYDPDPDAPGKTYTRFGGFLDGIDGFDP
EFFGISPREAVWIEPQQRLMLETVWEGLERAGYSPASLRGSRTGVFTGVAANEYAHLLSA
ESIDKIEPHFITGNALNAISGRVSFALGLEGPAVAVDTACSSALVAVHQACQALHSGDCD
LALAGGVNVLLSPVTTVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVR
DGDPVCAVIAGSGVNQDGASSGLTVPNGGAQQRLIGAVLARAGLTGGEVDYLEAHGTGTP
LGDPIEVQAAAAAYGDARTPDRPLLMGSVKTNIGHLESASGAAGLIKVVLSLQHEVLPKS
LHFDTPSPHIPWDTLPVRVVDQATPWHPHGRPRRAGVSSFGFTGTNAHVLIEEAPAAAPP
QPDTAPDAPVSVLPLSARSPEALTALAQRYEAWLGAHPDADIADVCLTAGTGRSHFEQRA
ALVVDSVDGARAALADLAENRLRPGVVRGEHTHRPTTAWLFTGQGSQYPGMARELFDSEP
VFADTVTQCAEAVEDLLAEPLLEVLFATDRETGGQAGKRLRHTSFAQPALFALEMGLARL
WQSWGVTPDVVLGHSVGQYAAACVAGVFSLADGARLMAQRGRLFGDLPEGGRMVAVFADA
ARVEDAAGGHPRVSVAAYNGPNTVLSGPGEDLEQIVATFGEDGVRCTWLETSHAFHSELL
DPVLDEFESYAAQLPFAAPTLPLVCNRTGAVLTGHTTLDAEYWRKHSRQPVQFAESVRTV
AALGCSVLMEIGPQPVLTGSAVQVWPEHLPAPRAIASLRKGVSDRRQIADALAAAYVGGH
RPDFAAVARRPRHVVELPTYPFQRRRFWPRSAGITVDGGVGPAVSGILGSAKELASGDSV
YTSRLSVKSQPWLSDHVIYGTVVVPGATYAAMALAAVGAPARARDVFFYEPIILPEKASR
EVQLTLHPTDGDWTFQVHSRPHGEAGAEWSLNAEGRVLAGADDTDTADDASDAPSPEPID
EAVERLTRMRPQELFDTFADLELAWGPTWSGSLKSLWLGDGEAIGDILVGEELTEHLGTE
PMHPVLMDLCTGVAFPAFPALLAAEQGVTDLYLPLRYGQVSVAQSMPRRFYCRATWHRAA
LDSETQVFDLDFVDRDGNRLGGIREFTVKRAPREALLRGLGGDATRLLYTVGWHEVPAPA
AEDPVPSGTWLIAGFDDLAALVPGCVPLPRTTESAALGQVLADAHQRGVGFSGVVWRAAP
SPESESGAAQAARLEGEIDHLLSAVHAVQSGEVKLPGGLWIVTERAVACESGEPVDPVQA
ALWGFGRTVANEEPALRSRLVDGDGSPEAVRALAILLAHPVDEPEVAVRQGKLLASRLVP
WARTGHLTVPRANDYVLAPTERGAIDNLRLTETEVAPPAEGYVQVRVEAAGLNFRDVLNV
LGLYPGDPGPIGGDFAGTVTHVGDGVTGLDIGQRVYGSMQGAFASRFNVPSQFLAPIPDG
VSAVEAATIPAAALTVRLSFDWARLEPGDKVLIHAASGGVGLAAVQMAQRCGAEVFATAS
AFKRETLRRMGVQHVYDSRSTDFADQILADTDGAGVDVVLNSLTSEGFIEATLRATAHGG
RFAEIAKRDIWTPEQMAQARSDIDYEIVALDTVMLTEPDRIRGLLTEVSEGLAKGEWTPL
PAEIYPLTEARSAFRRMQQARHIGKIVLQMPRPLQPQPDRTYLITGGLGAIGLHIAAHLA
QLGAGDIVLTSRRAPSADAAQLIDDLTERHRCRVHVVTADVGDEQEVTALLDRIRAEMPP
LAGVVHLAGVLDDALLSTQDLQRFRNTLAPKAYGADHLDRLTGDDDLDFFIVSSSVSSVF
GSPGQANYATANAFLDGLVAARRAHGLPATGVNFGPWARGGMASSEAATANISAQGLTPL
EPSAALSALSEVVANGTGQATVLKANWQRAAKVLGAARPPMLDLVLPSAGGEVTGDSELL
RQLQEIPVPQRAGFVTEFLQREVQNFLRLAQPPAASSRFLDLGTDSLMAIELRNRLHSQF
GGAFTINATAVFDYPTIGGLAEYLVGQLPDAEPPAESAD
>A0A0J6WQI9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium chlorophenolicum|TrEMBL
MTDDPIAIVGMAVEAPGGVATPDDFWTLLTEGREALTPFPADRGWPVHELIDASRRGGAT
PIRDLGGFLSTAGTFDPEFFGISRREALAMDPQQRVGLRMAWRALEDAAINPDDLAGHDV
GCYVGASDMRYGPAMDEFGEHTGHLITGTSLGVISGRIAYTLGLAGPAMTVDTSCSSALS
AVHLAVQALRAGDCDLALAGGVCVMGSPGYFVEFARQHALSDDGHCRPYSAHASGTVWGE
GAGMFVLQRRSAARRDHRPVLGVVQASCVNSDGRSVGLTAPSQDAQTRLFRRALDTAAAD
IEMIGMVEGHGTGTRLGDRTELRSLAATYGAGAPGRGPLLGSVKSNLGHTQAAAGALGLA
KVLLAAEHGVVPATLHAEQPSDEIDWAATGLRLAAEATPWPATGAARWGAVSAFGMSGTN
THIVVSVPDGEAA
>A0A1W1HKV9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Desulfamplus magnetovallimortis|TrEMBL
MTTPHLMKRVYPFFDNPVCQTSPPSPLSIAGEGENNAKRVHSNEKQAQGSCALGSLKSNV
GHLDTAAGVASLIKTVLSLQNNTIPPMPGFKEPNPKLDMETGPFFVNSQPLPWIKKDNTP
RRAGVSSFGQGGTNAHVIVEEAPDNMTSSSEADQWNLLTISARSPETLEKSTQRVAAYLK
ENLDQNPTDVAFTLQCGRHPFAFRRAVLSRSMMEGSKAFASLIDIDSAHKIKNINSTQNT
KDIKTKSFPVITGRALPHPPEVVFIFPGQDMQHDDMARGLYETEPLFRREVDLCKEILKK
NHAMDIADGWYPSAIELPSLIPERASDPVPLFIVEYALARMWQGMGIQPSAMLGYSLGEY
TAACIAGVISLEDGLGMAVAGARLLSVIKPGVMLGISMCEKDLLPLMGEDLDIAMISTPS
QCVAGGEKNAVEQLEETLKEKAVPYTRLPLDFAFHTRLMEPFLNPFRKELEKVKFNPPQI
PYISCVTGAWINAHEAMDPEHYLDLARRCVRLADGFKTLANHKELRESTSIWLETGPGQG
LAGLAMQQPDRPSNNTVISTLHDPRYHLGNTPSSSRTLGYNLKSDDHGESQRSNIHSDTP
ALLAAMARMWVLGLDIKWENRYMGKRRQRIPLPTYPFDSKKYWIEPAATNIGHNGNIECL
DKKPDTTSPSKYPDPSKWFYIPVWEEVPLEKKGDASGLWLVVGDSDGIDQALEKQGIKVI
SVSLDHAPLNLDHAPLNNEKDIPAKPDTLSMININFILNDERHEGWSSLLDTLKKKDMWP
DHIVYTGLLGNNFGGEDRFNKEGLFGGQNHTGGGEHLAKDDFSCQQNTILQYGYHKMVEL
GQALGKLAFSDQLSITVVGSGIFSMYDNEAVDPSRAAVIGPLKVLPQEYTNLKCRLMDII
IPDVSWKREKFLQRVTAELTARDGERSVALRGNNRWVEKFKPFDLPVFEEKISGTGISES
RSKSAGTYLITGGLGNVGLTLAGAITGLIQDSTVILTGRRPLPEPEMWNTIINSPDSDPA
LVHRLGTLQALLENGADIELMAADVTDMEAMQAIMNRIDGEDGEKAPLRGVIHAAGLVGA
DSFATVSETTHDFSMKQISPKLKGTHVLEQLLKDRHLDFCILCSSLSPILGGLGFTAYAA
ANASLDAMAISHNRKHPVPWLSVNWEGWRFEDEPSAGQAGASIAEMALTPADGVEAFKRI
LSMSGAICNCSPVTHSLLPDIPRIVVSTGNLDGRISQWVNIKEEKEQPSLARHPRPALLG
ECVPPGSDVEKELAELWEKLLGIDGIGIYDSFFDLGGNSLLMTQLVTQIRKAFKLELSLA
ELFDKPTIRDIAAQIEETVNGNGKKGGGEEGADEEEEDWEEGFI
>D3DDF9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. EUN1f|TrEMBL
GAAAVTVALRERLAGLPDAAARDELLLDLVRGHAAAVLGHADAAAVEPGRALRDLGFDSL
TAVELRNRLIEATGLRLAATLVFNHPSVRAIADHLAERLAHSAAPAAGTGTGTASGVPGE
EHPSGAGQADDDRDDPVVIVAMGCRFPGDVSTPAQLWEVVRDGRDVVGALPDDRGWDLTA
LYDPDPDQPGRTYVRGGGFLTDVAGFDATLFGISPREALAMDPQQRLLLEIAWEVFERAG
LDPTALAGTPTGVYVGTHGQDYGAGLAGASADEGYLVIGKAASVLSGRVAYAYGLQGPAV
TVDTACSSSLVALHLAAAALRSGEIDLALVGGVSVMTTPEGVLGFSRQRGLAADGRCKAF
AQAADGFGMAEGAGLLLVERLSRARRHGHRVLAVLRGSAINQDGASNGLTAPHGPAQERV
IRAALAAAGLSTADVDVVEAHGTGTTLGDPIEAQALLATYGQDRPAVRPVLVGSGKSNFG
HTQAAAGVAGVIKIVQALDHGLVPRTLHVDQPSSHVDWDAGALRLATEATPWPELGRPRR
AAVSSFGVSGTNAHVILEQGDPGPAPAAAPLDHSAPPEVVPWVLSAASEPALRAQTGRLA
AFAREHPATAPAEIGRALLTRATLTHRAVAVGGQPEELALGLAAVAAAEADPAVVTGRAD
VAGRTAFVFAGQGAQWVGMGGGLLASSAVFAGVVDEVAAALDGLVDWSLHDVLRGGGGAE
ALGRVDVVQPASFAVAVGLTAVWASLGVRPDAVVGHSQGELAAAYVAGALSLADAARVVA
LRSRAIGARLAGRGGMVSVLLPAHRVGERLPAGVEIAAVNGPDSTVVAGDPAGLDELVAG
YEAAGVRARRIPVDYASHTSHVELIERELAEVLAGIEPHSPRLPFFSTVDGGWVRDASLD
AGYWYRNLRLPVRFGPAVDALADAGYRAFVEVSSHPVLTLGISETVAARAGVPTVVTGTL
RRGDGGLDRLLRSAAELHVRGVQVDWAAAFSPAAGLPAALAADPPDGRTAVGGAAVGGRP
APSVELPTYAFQHERYWLAPAGSARGRRGADLAETGLADTGHPLLGAAVELPDSGDLLFT
SSVSVASQPWLADHAVSGAHLVPGAAWIETLLRAGAEVGFPVLDELLIEAPLAVPERDAL
TLRVTVADTDESGTRPVTIHARSRDAALGDAWTRVASGRLSAAVTAPEHGFEQWPPAGAQ
PVDVSDFYARLADEGYAYGPVFRGLRAAWTRDGEVFAEVALPDGASPGEFGLHPALLDAA
LQTAKLGVVPPADAGQVLLPFAWNTVRRHAAGARVLRVHAAASSPASATGPEGGSGGYGV
TLRLSDQTGAPVGEIGQLVLRPTDAARLAPGEATAGADALMEVGWVPVGIAAGGPTSPVD
AILDLTAAAAAEAGGSSGLEPADGLPGGDPARARALIERALDGVGAVLGRSDGSPLEAAA
ANGSSASPSEASSEVSPTAAAGVLAVLTDDPVGDPAAAAVWGLLRSAQAENPGRLVLAGV
GPGPGDAAAARALLPAATAVGETQFAVRGGQVTVPRLARLAVAPVEARPVVPPGAGTSAL
RPATDGVPPAAAFPADGTVLITGGTGTLGGIVATHLVRVHGVRHLVLLSRGGPGAPGADA
LRASLREAGAVVEIVAADAADRGALAAVLDAIPDTRSLRAVIHTAAVLDDGLVTALTPAR
LDTVLRAKADAAWNLHELTADHDLTAFVLFSSASAAFGGAGQGSYTAANGYLDSLAEYRR
ARGLPAVSVGWGLWAQRSALTGRLSAADRDRMARGGVRAMSAAEGVALFDGAVASGAAHV
VAAALDLAFLRERAAAGELTPLLRDLVRVPGPGGAGPAGAGA
>A0A100JUA9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces scabiei|TrEMBL
MEALRDALKETARLRRENRQLQAGVGEPVAVVGMACRLPGGVGSPGELWDLVESGRDGVS
GFPVDRGWDVEGLFDPDPDRPGTSYTRHGGFLHDAAEFDAEFFGISPREALAMDPQQRLL
LESSWEAVESAGIDPQALRGSRTGVFAGIMYHDYGPALHIPAGGVDGQRLTGGAGSVLSG
RVAFSLGLEGPAVTVDTACSSSLVAVHLAVSALRGGECSLALAGGVTVMSSPGTFVEFSR
QRGLSVDGRCRSFAASAGGTGWAEGVGLLVLERLSDARRNGHRVLAVVRGSAVNQDGASN
GLTAPSGPAQERVIRAALSSAGVSAADVDVVEAHGTGTRLGDPIEAQALLATYGRERSAD
RPLWLGSLKSNIGHAQAAAGVAGVIKMVMALQRRALPRTLHVDEPTPLVDWASGGVELLT
EQREWEPVEGRPRRAGVSSFGISGTNAHLVLEEAPPAPEPEATPVPDAAPVPLVLSARTP
DALRDQARRLLPLLRDTAGPAARDLAFSLLTSRSLFDHRAVLGGDRRAWEEGLAALAGGA
PGADMAAGEASATGPVVFVFPGQGSQWVGMAGELLAESAVFAARMEECERALAPFVDWSL
LDAVRSGQAWDRVDVVQPALFAVMVSLAEVWRSFGVVPDAVVGHSQGEIAAAVVAGALSL
EDGAKVVALRSQALGVLAGRGGMVSVGLAHDRLADLLADRPGLSVAALNAPSAGVVSGDP
DALAALLAHCEAEGVRARRIDVDYASHSAHVEEIRETLLEALTGLRPTAAHVPLYSTVEG
GWLDTARMDADYWYRNLRATVGFAPAVRTLAESGYTGFIEVSPHPVLTMGIEETVHEAGC
EAVVLGTLRRDEGGLRRLHHALGEAFVRGLPVDWKPALAGTGARLVDLPTYPFQRRRYWL
ETPRASDPAAPADDGLWREIEAQDSAALADTLGVDPGAVGEVVPALSAWRSERIRGWRAD
GWRHRVGWRPLTLAPRASLSGRWLVVLPAADSGADVLAAMTAAGAEPVPVVVSAPDQDRE
SLAASLRAASGAESVAGVFSLLAEETRPHPAQPDVPAGLSLTLALVQALGDIGTDAPLWC
ATRALAAVGGGERPGASAQAAVAGLGRTVALERPDTWGGLVDLPAVLDERAADRLGAVLA
TVTDEDQVAVRSSGVYGRRLLPVGPGRPAEARHSPGGTVLITGGTGGIGAQVARELAERG
AAHLLLLSRRGPDAPGADALRAELTALGARVTVAACDVADRAQLTAVVAAIPEEEPLTTV
VHAAGVLDDGTLDALDPARLATLMRVKVTAARTLHEVTDGIGLADFVVFSSFMGVLGSAG
QGNYAAANAALDALVAERRAAGLPGTSLAWGAWAGGGMVDDRIADRLRRLGITPMEPRAA
VRAMTAALTDHDELCVVADVDWQRFGEAVGLRATALLSSLPGAAGARTPAPAGPAEQDGR
DGQVRGQLAALPAAERSRHITDLVRTHAATVLRHGAATDIAPGRAFAELGFDSLTAVELR
NRLGTATGLRLPTTLLFDHPTPQALAAHLLAELAPSGPRTEEADSARPGGTIAVDDDPIA
IIGIGCRFPGAVHGPDAFWQLLTEGRDVIAEWPEDRGWDTDRLYDPDPDRPGTTYSRRGG
FLHDAGGFDAAFFGISPREALAMDPQQRLLLETCWETVEHAGIDPTALRGRPVGVFVGTN
GQDYPGVLDGAPGVSEGHVMTGNTASVMSGRISYELGLDGPALTVDTACSSSLVTLHLAA
QALRRGECAQALAGGVTLMTTPKLFVEFSRQRGLAPDGRCKAFAAGADGTGWAEGVGMLL
LERLSDARREGHRVLAVLGGTAVNQDGASNGLTAPSGPAQQRVIRAALTDARVTPEEIDA
VEAHGTGTRLGDPIEAQALQAVYGAGRTADEPLWLGSVKSNIGHTQAAAGVAGVIKMVLA
IGHGELPRTLHADEPSTHIDWDTAGLRLLGEPTPWPRTGRPRRAGVSSFGISGTNAHVIV
EQVPDADEADDAEGPGGADGTAGETATGGAAETRPSPARTLPLLLSARTPAALRAQAARL
LAHLDTGPGTPLPDVALALVRGRAALEHRAAVPGDDEAAARRALEALAAGTSDPELVTGL
AAPGRTVLLFPGQGSQRAAAGAALYRDEPVFADALDDVLAHFAPHLDLPLRDILFAAEGD
ERAALLHRTRYTQPALFALEVALFRLLDHWGVVPDLLIGHSVGELAAAHVAGVLDLPDAC
ALVAVRGRLMDELPGGGAMVAVEAGEDDVLQVLGLLGDSADGTVGVAAVNGPAATVISGA
EDAVLRAAEEFRRQGRRTRRLTVSHAFHSARMDGMLDAFREVAEGLTYAEPRIPVISDLT
GQLAPASELCSPEYWVRHVRGAVRFMDGVRSLVAEGATTFLEAGPGGVLSALVPACLPED
GPGAPGVTAIPLLPKGRPEAASVVAALARLHVRAVPVEWTAGHEGTAAPHVDLPTYPFQH
ERFWPRPAARKDADGAPTGSDAFWDLVGTADAPSVASLLGLDERAPLGDVLPALSAWRAR
RDQEAAAARHHYRVAWQPLALPARIRLSGSWLLAVPDDPAVTETAAAVERALAEHGAETT
VVRIAAGAGRAELAERLPAGATGVLSLLALTDLPHPDHAPLGAGLALTLTLLQALGDTGS
RARLWCVTSGAVAAGQDTPPSPTQARVWGLGRVAALEHPDHWGGLVDLPERLDPAALRGL
CACLGDVDGVDTGHGDGTTDGLAGEDQIAVRPSGLLGRRLTAAPAGVPASGGGVVPGDDA
AATGDDVTPGRQVTPGAVPAPTRWRPQGTVLVTGGTGGIGRHVARWLAQEGAEHLVLAGR
RGTAAPGAAALVAELEQAGARVTVAACDLADRAATAALVERLRAAGDTPRAVFHAAGTVS
DTRTDQCTPAQLHAELAAKADGADHLDALLADEPLDAFVLFSSIAGTWGSGGQAAYAAAN
AHLDALAARRRAHGRTALSVAWGPWEGTGMADGDAGAGLRRHGLVGLRPETALTALRQAL
DTGRTEVVVADVDWRRFVPVFTSGRPSRLLGALPETAAADAPFESGPSAGTAGPEDQADR
WRDRLTALPEAEGDRLLVELITTEAAAILGHESARRVDPERPLRDIGFDSITAVELRNRL
VTATGFGLPVTGLFDHPTATGLARHIREGLTGAARPAAGPDTTAPPAPHPTDPADDPLAV
VAMACRFPAGVRAPEDLWRLVADEVDAIGAFPTDRGWDLDSLYDPDPDRPGTFYSSGGGF
LDGAGDFDAGFFGISPREALAMDPQQRLLLETSWEVLERAGIDPLSVRGSRGGVFVGVAS
QGYGTGPGTSSDGVEGHLLSGTVTSVASGRIAYTLGIEGPAVTLDTACSSSLVALHLAGQ
ALRAGDCSFALVGGAAVMAAPDVFVEFSKQGGLSPDGHCRSFADGADGTGWGEGAGMILV
ERLSDARRLGHPVLALVRGSAVNQDGASNGLTAPNGLAQQRVIREALAHARLTTADVDMV
EAHGTGTVLGDPVEAQALLATYGQGRPADRPLWLGSLKSNLGHTQAAAGVAGLMKTVLAM
GHGTLPRTLHADDPTSRVDWSGGAVRLLDRARPWPAPGRPRRAGVSAFGMSGTNAHVVLE
EAPPEPAVPEPAVPEPPTVAQDTGAEPEAPSSPALPWLLSARSQPALREQAARLHAHLTD
RPELRPADVAHALATTRSALPHRAVVVGTGRRELLDALAALADRSAASGAVEGQARTGGR
TVFVFPGQGSQWAGMGSALLDASPVFAERVAQCERALSPYVDWSLTGVLRGESGAPSLER
VDVVQPALWAVMVSLAALWRSCGVEPSAVVGHSQGEIAAAVVAGALSLEDGAKVVALRSR
ALVALAGAGGMVSLAVSEDRARALLAPHGDRICVAAVNGPDAVVVAGRPDALTDLLAACE
RDGVRARRIPVDYAAHSAEVARVRDDLLDALADVTPRTGGTPLYSTVTGEPLDGSLLTAD
YWYRNLREPVEFARATERLLDAGFDLFVETSPHPVLTAGVEGTAERAGRTVTTVGTLRRD
DGDSARFLASLAEAWTTGAEVTWPDVVAEAAPGARRVPLPTYAFQRTRFWLPTPGRTAPA
AGAADGGAAQDRFWAAVDSGDPAGLAAALGADADATPEGFAPALREVLPVLSGWRRARLD
RDAVRSLGYQVRWQPVADPPAAPLDGDWLLVVPKQHTDDSLVGACQDALRLGGARARTVT
VDAGDAARTAQDVADAVADAARPVSGVLSLLALDERAAAEGAPVLAGTAATLELLKALDT
LGIDAPLWCVTGGAVAVHPDERLTRPGGAQLWGLGRVVGLEQPGRWGGIADLPPSPGPDE
ARRLAAFLTGGHGEDHLAVRPTGAHARRLVRAPAPDASAGRDWTPAGGTALITGDTGVLG
AEIARWLARRGARQVVLAGDRSADQAAVAALRDELAELGAELTVPDGRDPLAGLPGGAPL
TVAVHLARAHDPGASLAELTSEDLAGALRSALGPVAGLDALLDGHPAPDSVALAVLFPLS
GVWGAARRGAATSAYAALEALARDRRDRGSRCVTLALGGLEPAPAGSDPVESPLDANTVL
AALQQSLDHDEPAAILADVRWDRVVAAVPDPRALRLLSELPEAASAPGDATGDDEDDAAA
ELARRLEPLDEPARRRLLLDLVCDHAAAVLGHTGRQAVPADQAFSAVGFDSMLAVSFRNR
LRTATGVPIAATVVFDHPTPTALADHLYDGLCARPGPAVPALAELRALEAALTSADPRAQ
GADELGARLQDLVRTWARRTEPDTGPADTDAIGSASADELFDLLDNNFGMA
>A0A378X345|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia africana|TrEMBL
MSAAGSESASTAGETPDREQRIAAALRAARERLAAPRPAEPIAIVGIGCRFPGGITGPDT
LWDVVAGGVDATGEQPGDRWDVQRFYDPDPDKPGTIYTTRGGFLDAVDMFDADFFGISPR
EAHAMDPQQRLLLEIAWEAVENAGIAPQRLRGSDTGLFVGFSWRDYDRIAVADRPEAMNA
YAGLGNTPSIAVGRVAYTLDLHGPVSLVDTACSSSLVAVHQAVQSLRNGDCSTALAGGVN
LILSPLSTMFCCRIRALSPDGRCKTFDASADGYGRAEGAALVVLKRLSQAQRDGDRTYAV
IRGSAVNHDGRTGGLTVPNARAQEAVVRAALRAANIEPAQVNYIEAHGTGTALGDPIEIG
ALNSVFGAARAPLWVGSIKSNVGHAETAAGIAGLIKAALAVQRGAIPPTLHVREPNPRID
WASGSARVVTETTPWPAGSRIAGVSSFGFSGTNAHVVVEQPPVAVESATAVPSGLLTLSA
RSDEALRAQARRFALALRTVEPSRLESVCATANLGRNSFEHRLAVVAGSTTAMAAALDAH
TAGQRQPAVVTGHVPRGRAVRAALLIGHRGPGVEPLDRESYTGSGVFRAAVDECLDATSS
RESFRTALFAGLAPHQAQRVPGLADALAFVHRYATTRQLLAFGLRPAAVLGVGVGEYVTA
AITGILEPAVALRASVSTAALLGERAVARTGDRALLDAVLRETGARLCGHFGDRYLLEAG
PGGREPLLHRLRTAGIAATTHAELRDHVGTALADPGQPGDPEFTVVSAHTGARLGREAAD
PAYWSSRPLWPAQLDRAFGTLLELDCTVFTEVAGATLTELGSNRRTASESRWFTTGTTRG
ELIRCTAGLFAAGAVDDLRDLHGTHYPRITLPTYPFQRRRYWVEASGATHAPDAARTATL
DGAEPGDGRGTVPDCTVPGPPVRTGVDATPSTAPVAGAVESARPALSEADLFLLRRRVHS
VVTGSIRQVFQMPDSDPVDLDTPLQELGFDSLMAIELRTVLGRALALPIEAAFAFEFPTA
TAQIAELTARLADAPTRAPAPAAEPAMPESATPAASTELEHHNAAGPHPVSFDIRVSTTR
SPLDGLSESDLIALARAEVAALEEVLR
>A0A0J6VSH4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium chubuense|TrEMBL
MVSVEGRSDPVARFAVVGYAARFPGAPDADAYWELLREGRDAISEVPPDRWDAEAFFDAD
PGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRQLDPQHRLLLETAWHAVEHAGIAPST
LAGTDTGVFVGLATHDYLGMASDELTYSEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV
DTACSSSLVAIHQACQALRLGECDMALAGGANVLLTPATMITFSHAHMLAPDGRCKTFDA
AADGYVRGEGCGIIVIKRLEDALRDGDHIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
AALDRAGLDPRDVDYLEAHGTGTSLGDPIEAQAAGAALGDGRELDRPLLIGSAKTNIGHL
EAAAGIAGVIKVILSLEHETLPKHLNFENPSPHIPWDRLPVEVVKETMPWTRDTRPRIAG
VSSFGFAGTNAHVVLEEAPATVAADVPAGAAPVPDVAAGAAPVSDVAAGAAPVLRVLPLS
ARTPTALRTLAGRYRDWLTEHPEATPADVCFTAGVARAHAEHRAALVIDSRESALDLLGA
LADDRPAPGLVRGESYEAPKTAWLFTGQGSQYPGMARGLYDTEPVFAETLDACAAAVADL
LEKPLLEVIFDNDDAEALRLTSYAQPALFAVEMGLARLWQSWGLEPDVVLGHSVGQYTAA
CVAGVFDLADGARLMAERGRLFAGLPAGGRMVAVFAPAERVEAVTDDVPSVSVAAYNGAN
TVLSGPATDLERAVAGLVADGVRCDWLETSHAFHSALLDPILDEFEAATNRFTFGPPQRI
LIDNRTGTALGRSVTLDGAYWRRHARQPVQFASSVRTLAELNCKLLIEIGPRPVLTAAAL
AAWPDPATSPRVIASLRPTATDQRQITEALADAYVLGHLPDFRAVRPSTARMLDLPTYPF
EHRQYWFRDAREPAERQQRTGPRTAAIGLLEDGRIDELAALLGATEDDTRTRDILGTLAA
QHNQQRDAQSITDDRYEIRWDPAVATPHDTADTPSWILVGDDTPATRPLIDLLTARGHRY
QILGLPLSDAEEADVADAVRSAAAADPALRIVHIAGLDADASTSTRSLLRMQHRALPGTR
RLFRAAATAEVRSPIWLVTRGAQRVADGDVTAPEQACLWGFGRAAALEAPQLWGGLADLA
AGTAEEWSALVQRIATPAGPGIRDDQIALRGHDGYVPRLIRRTGQPNAQGPQIRSEATYL
VTGGLGAIGLEIAGHLAAHGARHLVLTSRREPGEAARQRIAALAEQHGCEVRVVAADVAD
AHDVARLLAMMHAELPPLVGVVHAAGEIGTTPMTDLTDDEIDRVFAGKVWGAWHLAEAAA
ELNLDFFVSTSSIASVWGGFGQTAYGAANAFLDGLSWRLRERGVAGSAVNFGPWAVGMAD
ARSRARLEERGVATLSPADALAGLADAMATGAPQSVVARIDWARFLPLYEQTGRRGLLAE
LNQELPQAVPAPTASGRTALVERLTEAPVQQRRTLLIDYLRDAVAEVTLSCPIHAYYGDD
DEIATAEKVXTRVDATEIREDAGFFDIGMDSLMAVELRRRIETGVGRDIPATLAMDHPRL
LDVADYLLGEVLGLAEAAPTRPATVVTARTDDPIAIVAVSCRFPGAPNPEAFWDVLAGGV
DAIREVPEDRFDIDEFYDPDPDAPGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQ
RLMLETVWEGLERAGYSPASLRGSRTGVFTGVAANEYAHLLSAESIDKIEPHFITGNALN
AISGRVSFALGLEGPAVAVDTACSSALVAVHQACQALHSGDCDLALAGGVNVLLSPVTTV
AASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAVRDGDPVCAVIAGSGVNQD
GASSGLTVPNGGAQQRLIGAVLARAGLTGGEVDYLEAHGTGTPLGDPIEVQAAAAAYGDA
RSPDRPLLMGSVKTNIGHLESASGAAGLIKVVLSLQHEVLPKSLHFDTPSPHIPWDTLPV
RVVDQATPWHPHGRPRRAGVSSFGFTGTNAHVLIEEAPAAAPPQPDTAPDAPVSVLPLSA
RSPEALTALAQRYEAWLGAHPDADIADVCLTAGTGRSHFEQRAALVVDSVDGARAALADL
AENRLRPGVVRGEHTHRPTTAWLFTGQGSQYPGMARELFDSEPVFADTVTQCAEAVEDLL
AEPLLEVLFATDRETGGQAGKRLRHTSFAQPALFALEMGLARLWQSWGVTPDVVLGHSVG
QYAAACVAGVFSLADGARLMAQRGRLFGDLPEGGRMLAVFADAARVEDAAGGHPRVSVAA
YNGPNTVLSGPGGDLEQIVATFGEDGVRCTWLETSHAFHSELLDPVLDEFESYAAQLPFA
APALPLVCNRTGAVLTGHTTLDAEYWRKHSRQPVQFAESVRTVAALGCSVLMEIGPQPVL
TGSAVQVWPEHLPAPRAIASLRKGVSDRRQIADALAAAYVGGHRPDFAAVARRPRHVVEL
PTYPFQRRRFWPRSAGITVDGGVGPAVSGILGSAKELASGDSVYTSRLSVKSQPWLSDHV
IYGTVVVPGATYAAMALAAVGAPARARDVFFYEPIILPEKASREVQLTLHPTDGDWTFQV
HSRPYGEAGADWSLNAEGRVLAGTEDADTADDASDAPAPEPIDEAVERLTRMRPQELFET
FADLELAWGPTWSGSLKSLWLGDGEAIGDILVGEELTEHLGTEPMHPVLMDLCTGVAFPA
FPALLAAEQGVTDLYLPLRYGQVSVAQSMPRRFYCRATWHRAALDSETQVFDLDFVDRDG
NRLGGIRDFTVKRAPREALLRGLGGDATRLLYTVGWHEVPPPAAEDPVPSGTWLIAGFDE
LAALVPGCVPLPRTTESPALGRVLADAHQRGVGFSGVVWRAAPSPEDESGAARAARLDGE
IDHLLSAVHAVQSGEVKLPGGLWIVTERAVACESGEPVDPVQAALWGFGRTVANEEPALR
SRLVDGDGSPEAVRALATLLTHPVDEPEVAVRQGKLLASRLVPWARTGHLTVPRANDYVL
APTERGAIDNLRLTETEVAPPAEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAG
TVTHVGDGVTGLEIGQRVYGSMQGAFASRFNVPSQFLAPIPDGVSAVEAATIPAAALTVR
LSFDWARLEPGDKVLIHAASGGVGLAAVQMAQRCGAEVFATASAFKRETLRRMGVQHVYD
SRSTDFADQILADTDGAGVDVVLNSLTSEGFIEATLRATAHGGRFAEIAKRDIWTPEQMA
QARSDIDYEIVALDTVMLTEPERIRGLLTEVSEGLAKGEWTPLPAEIYPLTEARSAFRRM
QQARHIGKIVLQIPRPLQPQPDRTYLITGGLGAIGLHTAAHLAQLGAGDIVLTSRRAPSA
DSAQLLDDLAERHRCRVHVVTADVGDEHEVTALLDRIRAEMPPLAGVVHLAGVLDDALLS
TQDLQRFRNTLAPKAYGADHLDRLTGDDDLDFFIVSSSVSSVFGSPGQANYATANAFLDG
LVAARRAHGLPATGVNFGPWARGGMASSEAATANISAQGLTPLEPSAALSALSEVVANGT
GQATVLKANWQRAAKVLGAARPPMLDLVLPSAGGEVTGDSELLRQLQEIPVPQRAGFVTE
FLQREVQNFLRLAQPPAASSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYPTI
GGLAEYLVGQLPDAEPPAESAD
>A0A0N0N117|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MTFMANEDKLRDYLKLVTTDLRQTRRRLQDAEARQQEPIAVVSMSCRFPGHVQTPEAFWE
LLVGGVDTVSELPADRGWDLERLYHPDPEHQGTSYARTGSFLYDAADFDPGFFGISPREA
TMMDPQQRLLLETAWEALERAGIDPATLRGEQAGVFVGSSDQGYGAAAAQSRDRVEGHML
TGGSGAVLSGRIAYTLGFEGPAVTVDTMCSSSLVALHLAVQALRQDECRLALAAGATVMA
TPRNFVEFSRQRGLAPDGRCKPFDEAADGTGWGEGVGVLLLERLSDARRNGHQVLAVIRG
SAINQDGASNGLTAPNGPAQERVIRAALTNARLTPDLVDAVEAHGTGTTLGDPIEAQALL
ASYGRERDGERPLRLGSLKANIGHLQASSGVAGVIKMVLAMRHGVLPRLLHLNEPTSHVD
WSPGTVELLAENQEWPETGRPRRAGISSFGGSGTNAHVILEQAPEAEPGTVQTPRTPAPA
VFASDGVVPWAVSGRGADGLAGQARRLGSFAESADSDVRPVDIAWSLAATRAAFEHRAVV
LGTERTELVDTLGVLAANGTAPGAVTGSFDVVPDGAVFVFPGQGAQWVGMGRELWESSPV
FAASMEACERALEPFVDWSLGEIVRGGAELVDVDVVQPVSWAVMVSLAALWRASGVEPAV
VVGHSQGEIAAAVVAGGLSLEDGARVVALRSKAIRAIAGRGGMVSVPLPLAAVEELLSGW
TGRIDIAAVNGPGSVVVAGDADALDELMVHCEAEEIRARRIPVDYASHTWHVEAIEGELA
EVLADVAPHSGSVPFFSTTEAELVDTASLDGGYWYRNLRQRVRFAEAVEGLVEQGYTAFV
EASSHPVLGMAVQEAAPDAVVVGSLRRNQGDTHRFLTSLAEAWVRGVPVDWTAVLGGRDA
RAVSLPTYAFQHQPYWFEPAAPQLTSGVVGDSADDEFWAAVEGQDLQALAGALDVAEDAQ
QEALAQALPVLSAWRRGRRAATAIDSWRYRIAWRPTGDPAAATTLDGTWLVVVPASHAGS
PLVRACLDGLATHGARTAPLFVDASDTDREQLAALMTESALNAAGDGNGARLGGVLSFLA
LDEHPHPQQPGLAAGLVAGLALIQACGDLDVRAPLWLATSGAVTTGDSDPLRSPTQNGTW
GMGRVAALEHPEFWGGLVDLSETPDERTAARLCGILAGTAAAAEDQIAVRRTGVLIRRLV
RTPAVAPGAADRTFTSRGTALITGGTGGLGGHTARWLARNGTEHLVLVSRRGPDAPGAAE
LEAELRELGARVTVAACDIADRDALAALVERVEADGPPIRTVVHTAGVGILIPLATTTLQ
EFADGAEAKLSGVANLDALFDDDRLDAFVVFSSVAGVWGSGDHGAYAASNAHADAVAEHR
RARGLAGTSIAWGIWSDEGGGMALDIVQEQLRWRGITFMDPAVAVAAMQQVLDRDECFIA
VADIDWDHFVPVFTAARERPLLTEVPEVAELLRAEEDRDRRPDPAAGESSALVARLRGLT
TEEQDQTVLDLVRGQVADVLGHSNPAAVELGRAFRESGFDSLTSVELRNRLNAATGLRLP
VTVIFDRPTVTALARHIREELVGTATELILASPAPAREPAPDDDPIAIVSMSCRYPGGAN
SPEELWRILAEGRDVIGAFPDDRAWDLDALYDPDPDREGTCYARDGGFVYDAGDFDPGFF
GISPREAIAMDPQQRLLLETSWEAVERAGLVPESLRGTPVGVFVGAANQGFGGLDNLPEG
VEGHIVTGSATSVLSGRIAYTLGFEGRAVTVDTACSSSLVALDMAVEALRSGECSMALAG
GVAVMVEPIGFIGFARTRGVAKDGRSKAFAKAADGMGLAEGAGMLLLERLSDARRNGHPV
LAVIRATALNQDGASNGLSAPSGPAQQQVIRTALAKAGLSTADVDAVEAHGTGTTLGDPI
EAQALLATYGQGRAAERPLWLGSLKSNIGHTQAASGVGGVMKMVLALQHGLLPQTLHVDE
PTPHVDWSTGAVSLLTEAVEWPSGEGRVRRAAVSSFGVSGTNAHVVLEEAPGVPDLEVVG
AEPVFVAGAGGVVPWVVSGRGAEALAGQAGQLASFVEADSAVGPVDVAWSLAGSRTAFEN
RAVVLGAESAELVAGLGVLASGEVTGAGVVRGAAAGGADRVVFVFPGQGAQWVGMGRELW
ESSSVFAASMEACERALEPFVDWSLSEVVRGGVELVDVDVVQPVSWAVMVSLAALWRASG
VEPSVVVGHSQGEMAAAVVAGGLSLE
>A0A0N0N6L5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
GAARRPGLAVVAGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLTAADVDAVEAHGTG
TSLGDPIEAQALLATYGQDRPEERPLLLGSVKSNIGHTQAAAGVAGVIKMVLAMQHGLLP
RTLHANEASSHVEWSAGAVDLLTDNADWPRTEERARRAGVSSFGLSGTNAHVVLEEAPLQ
GQPESVAPSTGSAGGPATGSVGSAGGAVPWVVSGRTAAALRAQAEQLAEFVAGDVTLNVA
EVAGSLVRSRSLFEHRAVVWGADRAELLEALEAVASGAESANATAGTARRDTRTAFLFAG
QGSQRLGMGRELYETYPVYADAFDAACAHLDAELPRPLREVVFGDDVELLNRTEFTQPAL
FALEVALFRLLESWGVRPDVLAGHSIGEIAAAHVAGVWSLADACRLVVARGRLMQALPTG
GAMVAVQAAEDEVLPLLNDRVGIAAVNGPQAVVISGAADAAEEIAAHFRAQDRKTTTLRV
SHAFHSPLMEPMLAEFRAVAEQLTYERPQLAVVSTVTGEAVAADELTSPEYWVRHVRATV
RYADAVRALAEENVTRYLELGADGTLTALAQATLDAPEAAVLVPVLRKDRPEAGALLAAV
ARLHVDGLPVDWTAQLPSSEPVVLPTYAFQRRRYWPNFTGVTLGDLGSAGVGSAEHPLLG
AAVRVAGSEEALFTGRLSLKTHPWLRDHAVTGTVLFPGTGFLELALCAAGQLGYDRVEEL
TIAAPLVVPERTGRLVQVRAGAPDESDARTVEVYSRAEDALDTDPWTLNATGSLTTTTPV
TTTPDLSAWPPPNAEAVPTEGFYDRFAEAGFAYGPVFQGLRAVWRRGDEVFAEVGLPDDH
ERLAGGFGVHPALLDSALHAMMFVSLADAGQGRLPFSWSGVSLRASGARSLRVRMVQAGP
EAVALHLADPTGGTVASVESLLLRQVSGDLAARAAAEGHRDGLFQLDWPKLTTSAGQHGF
GYGEVAVVGDDTDLAPGVPVHPTLAELPAVVPAHVLFAATTGHGSGTPLTDSTRSAVGRV
LDAVRTWLADERYEDARLVVVTEGAVALDETAPDPAGAAVWGLVRAARAEAPDRFALVDT
DGTDASRAALAQTLASALAAGEPEFVLRDGVAHAPRLGRVPAGGQLPLPADESAWHLDSI
EKGTLDNLALTPFPEAAAELTAGQVRIAVRAAGVNFRDVLNALGMYPGEAGLLGGEGAGV
VTEIGPDVTELAVGDRVMGMFPGSFGPVAVADARTLARIPVGWSFAQAASVPIVFLTAYY
ALTDLGGVRAGESVLVHAAAGGVGMAATQLARHLGAEVFGTASAGKWGTLRELGLDGAHM
ASSRDTAFEAAFLAATGGRGMDVVLDSLAGEFVDASLRLLPRGGRFLEMGKTDVRDPDTV
AAQHADVMYRAFDLWEAGPERIGEMLADLVELFNSGVLQPLPVTCWDVRRAPEAFRYLSQ
ARHVGKVVLTVPAPLDPDGTVLVTGGTGGLGALVARHLVTEHGVRHLLLASRRGLDAPGA
RELVAEMAELGATADVAAVDVADRDQLAAALHTPPPPHPLTAVIHTAGIVDDGVIGSLTS
ERLAAVLRPKADAALQLHELTRDMDLAAFVVFSSVAGTFGSAGQANYGAANAFLDAFAAT
RRAAGLPAVSLAWGAWAPGAGMTADLTEADLRRMARGGMRTLSAEQGLQLLDTAGLLTGA
APAHRAALLPVNLDLQALRAHADAVPPLLRGLVRAPARRAAETAGGGGAERQDLGATLAG
RAPADREQFLVDLVCAQAAATLGHASADEIEPDQAFKELGFDSLTAVELRNRLNAVTKLR
LPATLVFDHPTPTALAGQLLTEIALPEADGPDGPNGPGTAQGTSAGTAVTAAPLLVELDR
LEAALAAATVGGDDHVTITSRLQRLTAKWQEQATKGGAGHDTGTGSGDPGTALTDADDDG
ELDSVATADELFDLIDKELGMS
>A0A0N0N0K5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MDPQQRLLLEATWEAFENAGIDPASLRGSQTGVFAGASGQDYTSRVTKVPQNVAGHLVTG
NAGSVVSGRISYTFGLEGPAVTVDTACSSSLVALHLASQALRQGECTLALASGVTVMSTP
GFFLEFSRQRGLAADGRCKAFSAEADGMGASEGVGVLVLERLSDARRNGHEILAVVRGSA
VNQDGASNGLTAPNGPSQERVIRQALVNAGVSAVEVDVVEAHGTGTRLGDPIEAQALLAT
YGQGRSEERPLWLGSVKSNIGHTQAAAGVAGVMKMVLALQHGVLPRTLHVDEPSGQVDWS
VGAVSLLTEEQAWEADGHPRRAGVSSFGISGTNAHVIVEQAPDPVVEEPSVQGPVSPVVP
LVVSARGEVALREVAGRLVPVVGDGGVGVVDAAFSLVSGRAVLGHRAVVWGRDRGELTSG
LEAVHRGERGAGAVVGVASSGGRLGFAFTGQGAQRPGMGLELAAAFPVFADALDEVASVV
DPLLGRSLRGVLAEESGVLDRTGVTQPALFAVEVALFRLVESLGVRPDVLIGHSVGELAA
AHVAGVLSLEDASRLVVARGRLMEALPSGGVMVAVQTSEQEVLPLLTDPRVSLAAVNGPE
AVVIAGAEDAVQAVVEQLTGRVRRLRVSHAFHSPLMEPMLAEFREVAESVRYGAPRIPVV
SNVSGRIAESGELASPEYWVEHVRRPVRFLDGIRTLTDLGVSRILELGPGGVLTAMAREC
LPPDNNTLLLPSLRKDRPEPESMLAALAGLFTDGVDVDWSPLVAGGRVTPLPTYAFQRQR
FWLEESSEGSGGWGLGPAVVLADGEGVVFSGGVSLRTHGWLCGHVVHGRVVVPGSAFVEL
VLRVGDVVGCGTVAELSVDNPLAVPERGGLRIQVRVHEADESGRRRVTVSSQPESQPEDG
DGVWTRNVTAALIPTPVSDAVPEDLAVWPPAQAEPCGPDVWRDGDTLYTEVTLPPEDQER
ADTGTGTFLLHPALLEAVVQLADSYALSDPDAPLATLGWRSVQLHATGATALRLRLTYRE
DGPPALLATDSTGVPVLTGEVALRPLFATDLPDGSAPTASGVPTTPIRRRVVRAAETVPV
RERLAALQGAEREARLLDLVRTEAAAVLGHGSPTELDVQLAFLELGFDSLTATELRGRLA
TATGLTLPPALIFDQPSVVALARDLGNRLDIPQTSDQASQGSIGALYWQACEDGKFVEAL
GLVKMAARLRPAFDAAGLSGQVPAPVRLSSGPGGPGGTRILCLPGFSAVSGPHEFGRFAA
ALRGRREVWALPEPGYLDGQALPDSLDALVRLQAEAARRCAGDEPFALLGRSASGMLAHA
VAEQLERDGGRPVAVLLLDSYSPDVIRRKPWLETTLTEAVAERESGYSLRNDTRLTAMGR
YHEVFTDWQPRPVTAPTLLVRATEPYSAELARPEHADWAASWTPPHHTLDVPGNHFTILE
SSSESTAEALHDWISGELSD
>A0A1V2RSW5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MAEQGFGTFIEVSAHPVLTMAIEDATAVGTLRRDDGGLGRFLTSLAEAWAAGVPVAWERL
FTGARRVDLPTYPFQRRRYWLDAAPAATRDVASAGLAAEAHPLLGAGLPLAGSDGHVFTG
RLSLAAQPWLADHMVHDVVVLPGTAVVELALHAAARTDCGGVEDLTLEAPLTVPEDGETQ
VQLAVGGADADGRRPVTLYGRGADDQPWTRHAAGTLAADAAPAAFTLAAWPPADATPVDV
TELQARLAKTGLDYGPAFRGLRAAWLAGAETAPEVFAEVALPEAAGGGFGIHPALFDAAV
QAMGAGRLVAESDAARLPFAWSGVTLHTPAGAMLRVRLTPALDAAGAQEGVTLHVADGTG
APVATVASLALRPLVAAQLRRPGGQDDGLYRVEWTPLATGTATDAATGAADAEPDAEPVV
FADLGSDPADPRGPARGAHVLTAHTLTLVRDWLADERSATARLAVVTSGAVAVRQGEPVT
DLPAAAARGLIRSAQAEHPDRFVLADIDDDPASRAALPGAVAAAVAAGEPQLAVRRGAVT
VPRLVRAPAAPGPAPRAAGAGTVLIVGGTGTLGRLLARHLVAEHGVRHLLLVSRRGPDAP
GAAELETQLAAFGAEVRFAACDAANREALAAVIAAIPAAHPLTAVVHSGGLLDDGVVQNL
TTRQLARVLRAKADVATHLHDLTAGHDLSAFVLFSAAAATFGRQGQGNYAAANAYLDALA
AHRGATGLPATSIAWGLWEQASDMTGHLGGDARSRIAAAGMQPLDAAEGLALYDAALRGG
EAVVTAARLDPDALRGDDIAPLLRGLARPAAAPAPAGAGPAGAAGELLRRRLDPMGDEDR
ERALLDLVRTHVAEVLGHGSLNAVPPQRGFLEAGFDSLTAVELRNRLARALGRRLPAVLV
FDHPNPLRLARHLRALLWPDRDRPAPQPTVTVTDQAPAPEPEPEPEQAQEPAGDVDALLK
DATADEVFAFIDAQFNEAQSTDQQKGGPRGDD
>A0A425HS93|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii CAST|TrEMBL
MMTRLPLCQQQAPPSLAGCHMLAAFQDIPERPLNRDLKELWAAYGENPFGNVLECWNRSI
PDEDAVVWLNSDGEISETTTFSELFSRITRLSSFLRAAGLQVGDRIILCYPPGTDFVTAF
FACITSGFVAVPVYPPDPSKGLSDVPRFCDINEIAGCKTALTNSLYKRVVQVITTVAKDS
RWRSVHWVCTDDVIKRHAEEAKNSVGPDFPNLSPHHPAFLQFTSGSTGNPKGVIVTHGSL
LHNCHLCWSAYQFPSHYENDGDDENITNHDFALVNQREFWRRRQEISIKSRGHRLRAFSW
LPVYHDMGLIGFVCSPILCGATLYQMSPIDFIRRPWLWLQGMSKYDCICCAAPNFAFEVV
TRKMPDNVYEHLDLSRVCGFLSGAEPIRASTIDRFCEKFGPKGVRRCAVCPAYGLAESTL
IVTARKTFQTVPKLLIVDSFQLQHEKTVVALKPEATVTMDSEEYQVLVGCGVPLEGVQVR
IVDPETKKELPPGKVGEIVVYSSSVARGYFGRPDTTKETFCYSFTDLQGKQTPPLGMRTG
DGGFMYEGELFVAARLKDLIIIRGRNFYPQDIEEAVDKVAMVRPGSSAAFAIEVDGHEAL
AVAAEVRLEEGIKGLWLRVKRQFDRSHYEQIVRDISKSVAANTGLTIHRIWLLRPRTIPK
TSSGKVRRSLTKEKLVSGKLEGILLDHAHHQHQAFYHDGPGGSRSRTRTGSGATPSGGAA
TRDGTASSNPSGDAHPKNSNTSNSITDSSHSVQRGSLRGDACVAGGRLGPSASHGGVHHE
KDHKHRGDGSGMSSPDQVPGAGAAASESSAHVALTEKVKQTVFEAAKTVLGSSEIPEIDA
PLHELGVDSIGAVEFSELISAELQVDVEPTLLFNYPTLSDVIDFFVRELEGKGSEDLAVS
LEKTGARETTTAIIGAACNLPGGTTSLNAFWDLLMCGVDAIAEVPRSRWDVEEYFDPDPG
ADGKAYVREGGFIEDAEMFDAAFFRISPSEAKSMDPQQRLLLEVAYESLYDSGYTREGLQ
RASVGVFVGCCSNDWYQVCSQLELGISSYTTTSYAPSIIANRLSYTFGLLGPSMTIDTAC
SSSLVALHIAAQELQGGSCMSAVVAGVNLMLSPHITVAFCKSRMLAPDARCKTFDASANG
YVRGEGLGSIVMKRLSQAEKDDDRILCILRGTAVNHGGRSASLTAPSGPSQQRVIRTALR
QAELTPGDIYFVETHGTGTSLGDPIEVGALKSVFGASRDAKTKPLILGAAKTNIGHLEGA
AGIAGVLKAMLALRYKHIPPNLHFKQMNPHIDVREFNVVVPTAPMAFPREDGGRLFAGVS
SFGFGGANGHVILQEALQQPSGDKPPCKRHSKRSIICFMFTGEGYEVSCMGRHLYETDDV
FKEIITKCNDILKRWLNVSLLSILYPPADKKMEMDKMMCQARFGHTALFAFEYALAESMV
SKGVKPDVVFGVGLGELVAAAFSGVMSLEEALYVVTQRAKLIDNLPPFEGVMVACRVSEQ
EVEMALSEMEINSRQSISIAAVYGRKNLILSGEQSEIDNVLMKLNIAGRWKYLPVHNVLT
MNLVSDIIPPFTHLMSTVKLCRPKVRLVSSTTGEFVDKEALSGRFWSRQVSQTVQLQQAV
GNIVASGCSLFVEIGPQVVLTKLAQQSLNGNAKDVTWVPAYDTTSDDVRVFENAVMTCNE
AIKIIGKERSLEEGQHGQEELIFHRKPFPWTEIPHPFLSGHKFTEKDDVVFENAFPRRAI
PLIADHAVNGTAMMPGAGMLEMVGAAALALDLRTTSGAVSLENISFERPMLIGAHRVTYE
YNRRHSLGEGGGAGTSPRTVRTPRLVNHAYTRLGFREKSAEKAISETAGPASTEGGRTPV
AGHHHGSYTKAGVLEDIKDYAHNVLRRAAQHAEEIDVHTPVPPSMAPPSIVARHPREGSY
GSMSRTSGIMGSNDRGDGLTVPLSVEMAIRCRVTKMKEVELSTVWDDEVTDHCFATIVIA
DKKQETYSSLQEVRCRCTERMDVNEYYDMLYDAGLQYGPRFRTIQELYRGEKEALARVHF
VGNVKQDPFESGFLIHPAVLDGALQAAGCLLEQSHSGNKVMVPVSVGSATLTKVEVFQPC
WAHVRLEETKSKAATLNVTIYDEVTREVVASLQNAVLRQVDPSASVVATIPKDLLWKVNW
QLVVEGDKEVVGRTPKVLFIGGNIELSEALENAMGSTCKTLSVDALPREKAELQKVLDAE
QWQAIVYVEAVTAGVYDALDVMNAAVRLVQAHYLNLNSGKAVGALWFVTRDTVFRDNGAD
KPGVEIPAHAGLWGLAKAARLEMEVSAGSPISMGCLDVSGADVSSMAQQILHALKSKVLT
MRETEVAVREDGLYVSRLAPQTEVDVRGAIEFHMPERGAISNLVLRPQAFASRLPPEDGQ
IELRVRAVGLNFRDVLNVMGLYPGDPGPPGADCAGVVVAVGDNVEHIEVGDCVFGVAQGC
LRTYVTTDSQLLRRMPESMTFEQAAALPVVATTVEYALHDLAKVKAGDKVLIHAVTGGVG
LVAVQLCKRVGATVYGTCSGGKKDAFAKSMGVQYVSSSRDAKAFAEDMRTFLGEDGKVDV
VLNCLIDDFIPESLKLLGPYGRFMELGKRGVWSKEKVAAERPDVQYELIAVDEMMEKDPI
WFGGMLVRVRGLVAEQKIQPLPMHVFDLADTGENGGVAAFRFMQRAQHMGKVVLKIPSPV
EEASKNGSIVITGGLGALGMVVAGWLAEEGARHICLLSRREEAPQPGEIPGWDWLRTINC
DVQFFSCDVSKYDSIRSVLRTIQTSVAPITGIIHTAGALADALLDSQTPELMKKVYNGKV
QGAWNLNRALEELGLNEQLKLCVFFSSVTSLFGNFGQANYCSANACLDALAQWRRAKGLC
CQSIQWGPWIEQGMAAELKQQVERNGMKGISNEVGLRVLHDAIRQQEKATPVIGCQAIKW
KLFMHRYIEQPPFFTNIEMDLQVTSHDSNTVLRNLPPSERRDYIKAQVAAAARQVLGSSS
PPPFDTPLQDVGVDSLGAVEFRNVLSKKLGVKLSATTLFDYPTLNAIIDHLCEVFGESSQ
KDNLSTKLGALSENDLVQEGMAIVSMSCRLPGNSTCPDLFWDMLMRCTDCVCDIPLTRWN
AEEVYSEDPDLPGKCYTRRGAFIENAEYFDNSFFGISPSEVKHMDPQQRLLLEVAYEAFA
GAGLTKEKLLGANIGVFVGACNHDWTYLIQEDKISAYTGTGSAGSVIANRVSYCLGLRGP
SVPVDTACSSSLVAADFAFEKLMLRDCTMALVTGVNLMLTPHLFIAFSKARMLSPDCKCK
TFDASADGYVRGEGAGAVLMLPYADAKAKQMTIQAVVKGTACNHVGRSASLTAPNGPSQA
EVIRMALRRAGMKPNDLKFMESHGTGTSLGDPIEVNAVRTVFAPGREKTKPLLIGAVKTN
IGHLEGSSGIAGLIKACLVLSRREIPPNLHFKTLNPHINIEDFPVQFVTDFVSLDSVEST
RKKNTAGVSSFGFGGVNAHVLLEEATRDQNATRKEENRPKICFMFTGQGSQYVGMGRHLY
EKEPVFREAITRCVEIAKEYLPLPLLSVIYPSPDERDKMQEAINETLYSQPAVFVISYAL
LELWKSRGVEPDMVMGHSLGEYIAAVCSGVISIQDGLKLVLKRAQIMSRAPSRNGVMVAC
RATAEQVEEAIHTLFGDGEKNVALASVNGLKSVIVSGNQQDVQAVLRQLGAASRAKMLRV
SHAFHSPLVKDTVAPFKRVLETVRLSKPRVMFVSTVTGKVARDELQNTNYWAEHITKVVR
FCDAVQACIAQGAKIMVEVGPRPTLSNMGKGCLPQTTADEVQWINSLEPETLSSAVFDSL
SALAKAGSGAMPAVFDRKFFPWTETCHPLLGGKNTRPDGSVVYSALLRDLVKALFLDHVV
YGKALLPATCLIEMMASATTHMISNHDEEKLVALSQVVFEKPLLVPDETSLSVLVTVETR
GQVRVASQVSNSEEEAEDHAVCQVNIVDALPAAPALTEIRARCKTEIEASQLYAQLHNVG
LQYGPRFQTIVKVFKGEDEVLGLLQAQNVTNFETGFMMHPAVLDGALQLSAVLAFEKGSS
RAMVPFGVDTVLLKSCPPDKELWARVVMNRKGVSSASATVHLYDFDGEPIAVLMGVTLRP
IEFNTAADIPRELLWEVEWESAGSYSMPQDGSLATPSGTDDSGAEDVTRTPSPLVTGENE
NTPSREVPSALPGLSTETPRASKPLSTDETSGAVLNKSVHSVLLVDYAGGHREVVASIRD
TCDVEVEVLSKPGSPELYAQQLRQFAEVVATKTETVPLSTILFLALDEATPAEQLAGGLL
ETVKVFAVEKFKKLPCIWVLTSGAQGPTRSVVSPKHAGLWGLMRTVRLELEMQIGKMVRF
GCVDLDKNLEVSVALHFILQKRTEEPFEAEMILRCPSEDSEKEPGTAEVVNRRERSASFV
SVGPEPVVPSTTDASAKSSVTSDRMALTPGALSCFDETANSTEKLIFNAFCPRLHRSPIP
VRGAVELHMPERGAISNLVLRPQAFASRTAPQSHECEIRVRAIGLNFRDVLNVMGLYPGD
PGPPGADCAGTVVAVGSGVRHLKVGDSVYGIAQGCLRTYVTTNGNLMRRMPESLTFEQSA
ALPVVAATVEYALHDLAKVKEGDKVLIHAVTGGVGLAALQFCKRVGATVYGTCSGGKKAA
YAKSLGVKYLTSSRDASAFAEDMREFLGEEEKIDVVLNSLIDNFIPESVKLLAPGGRFME
LGKRGIWTKAQMAAERPDVYYETIAVDTMMQEDTVWFGGMLDRIRDHVDSGNIPPLPLHV
FEMTDPLAGGVAAFRFMQRAQHIGKVVIRIASDLEVKIPSTTEPAATETAMLAEAGTQGN
ASIGTSTQQIADRTYLITGGMGGLGLVVAQWLVEEGARHIVLLSRRGEPSDTVKQSSIWE
YLTEKERTCVSVLPL
>A0A2W1JVA9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Acaryochloris thomasi RCC1774|TrEMBL
MHDFSTLVELLRYRAQHQSDQTAFIFLQDGETESARLTYSDLDRQARAIATQLQSLGMAD
ERALLLYAPDLSFVTAFFGCLYAGAIPVPAYPPRSKQMMARLEAVITDAQAKVALTTAGL
LSKIEQQLGGLLSLQCLATDTLDVALADGWQEPQLTAQNLAFLQYTSGSTGNPKGVMVSH
GNLLHNSSLIYDFFGHSAKSQGVIWLPPYHDMGLIGGVLQPLYAGFPVALMPPVAFLQKP
VSWLRAISNFRATTSGGPNFAYDLCARQVKPEQCEGLDLSHWNLAFTGAEPIRAETLDLF
AETFAPYGFKREAFYPCYGMAETTLITTGAVHQDPPVLKTICEEGITHNRVVSGTPDQPG
TRTVVSSGRVPADLKVAIANPDTLTSVDNSGIGEIWVSGPSVAQGYWQQAEKTEQTFNAY
LKDTKAGPFLRTGDLGFLQDGELFVTGRLKDLIIIRGRNHYPQDIEATVEQSHEALRPAC
GAAFSMEVEGEERLVIAQEVQRTAIRRLDSDAVTAAIRKAVVQQHQLQPWQIVLLKTGSI
PKTSSGKIRRFACRQGVVENNLNVLGQWIDPASAQPLEQNVCESSSESPRPQPTSAMAEA
IQDWLRNNIARRLGLQTADIDPHQPFSESGLDSMAAVQLTGELQDWLGRSLSPTLVYDYP
SIAALAHYLGTEAVIQAPQIEGHAVEAIAVVGMGCRFPRAENPDAFWNLLSNGVDAIQKG
CSRVPHAPGGYLEQVDQFDAQFFGISPREAEYMDPQQRLLLEVVWETLEQAGIPPHQLAQ
TATGVFIGMSSSDYAQMPQDVSAYSGTGNAHSIAANRLSYLLDLRGPSLAVDTACSSSLV
AVHLASQSIRQGECDQALVGGVNLILSSTLTDTFAQAGMLAADGRCKTFDDSADGYVRGE
GCGVVLLKRLSQAQADGDNVLAVIRGSAINQDGRSNGLTAPNGPAQQAVIHQALAQAQVT
PDQISYVDAHGTGTSLGDPIEMSALKTVLLQDRDPEQPCWIGSVKTNIGHLEAAAGIAGL
LKIVLALQHESIPPHLHLNEINSLIDLKGTPLDVPTQHRAWSQAQRFAGVSSFGFGGTNA
HVVIEAAPQVAEVPPTPQPDRPWHLLTLSAKTEPALRELVLSYVDHLQTSPNLADLCYSA
NTGRSSLEYRFAAVSDSISTLEQRLTDYLEGKKTAHSGAAGGSQTAFLFTGQGSQYSGMG
RQLYKTQPLFREILERCDRILQNYLDQSLLDILYPPNAASESTLERDLLDQTAYTQPALF
AVEYALCRLWQSWGIQPAVVMGHSVGEYVAACVAGVFSLEDALKLVATRAHLMQKLPQTG
AMVAIFASATRVQEMLQPYAASATIAAENGPENIVVSGDHQTIESMVADLTTAGIKMRWL
RVSHAFHSQLMAPMLDAFRQVANEVSYRLPHLPLISNVTGQRAAEELTHADYWCQHILET
VRFESSLQTLNTMGCQTFLEIGPQPTLLGMGRRCLPKSTGAWLPSLRRQQADWLQLLQSL
GTLYTQGLAPNWSQFEAGYHRQRLPLPTYPWQRQRYWLEPKTLPINASETSVVQWIKQGQ
TEPLARWLQQSMALSADQAALLPTVVNHLVEQHQQEQQTSALEDCLYQVDWQPQSVDASA
VATGRWLLLMDPAGEALATQLETQGHTCLRVYAGAAYHHQGQKWRIDPSQPADWKRLWAE
ALTDEQPPLAGILQLWNLASDRPEALAQIADCQAVLYLLQTLTAALPTALKLQPRFWIVT
QEAIRLPSDQNMEQRLAQSSLWGLGKVLALEHPHLWGGLVDVDTLGSAALLAELAHPHTE
TQVALRGQQRYVARLQRSQVPVQNVKQAICHPQGTYLITGGLGALGLQVAQWLVTQGARS
LVLVGRNAPSAAAIEVLQCLEEQGVVISTAPVDICDRNQLPTLQSTLASSPPLRGVIHAA
GVLKDGILEQQTWEQFQQVMAPKVTGAWNLHTLTQDQPLDFFVMFSSAASLLGSPGQGNY
AAANAFMDALAHFRRQQQLPALSINWGPWAQAGMAVQNEKTLTASGIDPIPVAQGLRLLE
MLIANGEAFPAQVGALSVRWSDLGSYASSPYLQALIQAKPSVRESRIFETLKEMNICDRT
SHLTHYLQQQIAHVLHLQPANIDIEENLLEKGCDSLMMMELLNQIQQDLQLMLYPREFYD
RPRIQVFAAYLAEEFERSHGAQPLTDASDLEEDLDTDFQTFATPTAKPTTTDPPSDRLPG
IVFILSSPRSGSTLLRVMLAGHPRLLSTPELHLLPFETMAERAKDLSLSNLGEGLQRVLM
DLKGLGVKTSQSLIQDLVQRSSPIQNVYAMLQELAGSRLLVDKSPTYAMSLETLGRAEEI
FADAKYIHLVRHPYAMIESFVRMRMDKLIGAGDGNPYRIAESIWTRSNQNVLQFAKTLGS
DRHHLIHYEDLVSEPQKVMQRLCTFLGIPFDPSVLQPYDGQRMTDGLHQQSLSLGDPNFL
KHNRVEKALGDAWRKIRLPHKLGNFARHITLQLGYDLPEAEPEPGAMLAETSLSLGDLEL
CLCTWGPEEGPLVLCLHGILEQGAVWDPIAAQLAAQGYRVIAPDLRGHGKSGRTVTYQLQ
DFLADLDQLVPKLTDQPVTLIGHSLGSVVTALFASVRPQWVRQLILVETILPAAENNTDP
ANQLLTHLDYAASPPEHSLLTDQAAAAHRLQQATPSLSPQFAQLLAERATQTDGVGVRWR
WDPILRTRTSLRGAPFDREGYLQLLRRIQMPVTLVYGDRSRFNRPQDLSDQQAALPHAQQ
ITLPGGHNIHLDASAELSQQILALLDSAEVQTREQH
>E0U576|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Gloeothece verrucosa (strain PCC 7822)|TrEMBL
MMLVNTSQASTVIAIVGMACLYPDARSPQELWENVLSQRRAFRQIPKIRLSLEDYFNSDR
SSADTIYSSQAAVLEGYEFDRLKFKVVGETFRAADLVHWLALDIADRALADAGFVEGKNL
PKETTGVLLGNTLTGEFSRANTLRLRWPYVRRVVEAQLLKQGLSAQERQDFLRDLEIKYK
EPFSEIGAESLAGNLSNTIAGRICNYFDLKGGGYVLDGACSSSLLAVANACSALSVGDLD
VALAGGVDLSLDPFELVGFAKAGALAQQEMRVYDAKSEGFIPGEGCGFMVLMRYEDALAQ
NCRIYSLIRGWGISSDGHGGITRPEVDGQLLALQRAYHKAGFGADTVAYFEGHGTGTAVG
DATELQVLSQIRKRNAVLPAVVGSIKANIGHTKAAAGIAGLIKATLALHSQMIPPTSGSQ
IPHPLLTENPAVKTLQEGQLWPSSQPLRAGVSAMGFGGINTHIVLEGLASVPRTRVTPRE
SQLIAAPQDAELLLLSAQTLEQLQEQVRHLLTIAPQLSHAEVGDLAAQLAKTLDPSLPLR
AAMIASNPQELTDHLEKISSLEQLPPLSRGVGGINLCPDLRVNCCDVFLGTAHKTPRVGF
LFPGQAAPVYLNGGAWERRFPWLKEIYTQANLPREKDLKSTVIAQPAIITSAVVGLQVLE
HLGITASIAVGHSLGELSALHWAGALNATSVINLARVRGQAMAENPTGMMASIAAPEQAV
RQLLNGRVVVIASLNSPSQTVISGEVLGVNDVLEKAKVKGIKTVKLPVSHAFHSPLVSGA
IQPLKEYLATIEISPLQKPVISTVTASFLSTHQDLRSLLVEQITAPVRFIDAATLAAKEV
DLFIEVGSGEILSGLIGDFLSVPVMALDAGAKSLKGLLKAVAAAFVMGIPINHRALFEDR
FTRPFNLHWQPKFLLNPCELAPSLSEKTVVSPNPSPEQTEKQKISATVSPLECIRQLVAD
KTELPLEAIRDDHRLLSDLHLNSITVGQLVAQAARHLGLSPPVSPTDYADATLAEIAQAL
ENLASIGDVSKVEEIPTGVEAWIRIFSVEWVDTPLNHQLKDHSLSSNWQIIAPTDDPLIA
SLQQAFNLCEGSGVVVCLGPKRNFSDMDLLLEGCKKLLHSSNLEGKLVLVQHGGGAASFA
KTFFLENPQITTCVVDVPVEVDPRQAAQWITSEAALGRGYCEAYYDPQGNRRSPVLRLLS
LEDHPETISLDCKDVLLVTGGGKGIAAECALSLASDRGVRLALLGRSQPDTDPELEQNLS
RIKALGIPVMYLSVDVTDPQGIKAAVSQIESQLGTITALIHAAGVNHPKLIKHLDKNDVL
CTVAPKVVGLQNLLAAINADHLKVLITFGSIIARTGLPGEADYALANEWLGRDLEEFQHH
YPHCRCLNLDWSVWSGVGMGQRLGRIESLIQQGITPIPPDTGISILRRLLNHRLPTPSVV
VTGRFGTPPTLKIEQPPLPLLRFLEQPKVYYPGIELIVDVELSPQTDPYLNDHIYQGERI
FPGVMGLEAMAQVATALISSWPGDSGDQITFEKVRFNRPIICEDQPLKIRIAAQRTENGQ
IEMALRSEQTQFSIDHFRAIYHVSSHHVRQKPTNHLSATECRQNSTPLNPQQHLYGQILF
HQGRFQRLQQYQHLRATECIATLSRHQESWFSRYLPQDLILGDPGAKDAVIHALQACVPH
ATLLPVGIEKLIIYAFPSVETLIVAAQERQRIGDRFIYDLDVLTPDGMVLEHWEGLTLEI
VQHRDSQIAWVANLLSPYLERKIKEVLPSADLRILVDQDETVDRRIRSDRSLQALTSKGV
IITRRPDGKPEVNQKTSVSVAHAGNLTLAVAGSGAVACDVETVISRTTETWSDLLGTSKF
ALASALAASTGESLDVAALRVWAAYECLKKAGAMLNAPLMLSQTRADGVWLESGEMMIAT
FVISVQQQENPCIFAILVNHQDRKNEAFNQLEPAFSTPIELSLNF
>A0A3E2MS72|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium marinum|TrEMBL
MSTNGSAGAADPIVISGMAVEAPGGIDSPASLWAALAESRELLSPFPRDRGWPVDDLLSV
SDLEGWGQVCDSGGFLDGATTFDPGFFGISAREAIVLHPQQRVAMRVAWKALENSGINPG
STAGTEGGCFVGMSPMEYGPRASVADAYSGHRIASLGQLGGAARISHSLGLIGPSISVDT
ACASSLSALHLAATAVREDECEWALAGAVCVMGSPGAFYEFARLNALSEDGHCRAYSDNA
TGTVWGEGAGMVLVERESRARREGRRIYGRIAAIRTNHNGKGKPILVPRVRAQEQVIRKT
LEVAGIDPVEVGMIEGHGTATPAGDPVELIALFKTYGAAGSEALLGSIKSNAGHSQAASG
ILALIKLLLAGQHGQIPPTLFADNPTKTVDWDLTGLRLATKLHEWEPKHGVRYGAVSSFG
AGGANAHAIISMPAAGVGQ
>D0LQX8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2)|TrEMBL
MSAPTSAELLAWIAEDLGAQLALDPQALDPHEPFSRYGLDSIGALALTRALGHRVGRALS
PVLVWRFPTPFALAAHLGEGAEEGADAGDAAGASAPASASSGAAAAGGPAADEPIAIIGM
SCRFPGADDVAGFWELLRRGGDAIAEVPGDRWDGAAWAARPGAAGARRGGFLTDVRGFDP
LFFGISPREASTMDPQQRLMLELTWEALEDAGVVPSALAGSQTGVYVGAAWVDYARLLYQ
GDGAGLTQHTVTGHHRSILANRISYALGLQGPSMSLDSACSSALSAVHLACAGLLRGDAS
LALAGGVNLNLLPESTHAMVAFGALSPDSRCATFDAGANGYVRGEGGAVVVLKRLSQALI
DGDPIACVIRGSAVNNDGASNGLTAPNPAAQEALLRAAYERAEVPPAQVQYVELHGTGTQ
LGDPIEASALGAVLGRARPAEAPLVVGSAKTNVGHLEAAAGMVGLIKAALCIAHRQLVPS
LHFERANPHIPLDELHLRVQTEAGPWPAPRQPLVAGVSSFGMGGANAHVVLAEWPSPPAA
IYPLAAGSAEALRERAQAWLDALAARPPDVDAPPRAPALPARAPDAPARAPDAPEHRLAL
SARGPDELAQGLRDFLDGRDSPRLARGRREGAGAPPVVFVYAGQGAHWLGMGRSLIHREP
LFRASLETCAGLIEERLGWSLLAELTAGPERSRLDHVEIGWPASIAIQIALTALWRSWGV
APAAVIGHSGGEIAAAYAGGALNLEDAIEVICAYARKLASVRGQGAMGLVGLSWDATGEA
IAGRRGVFRAIEHGVDATVLAGEPGALDALVRELAERDVFCRRLPVDVAPHSPLVEHLRD
ALQDELRGVRPRPSQVPVISAALGAALPGERYDGGHWVHNFCEPLSFSTAIDGLLGDGYE
VFLEISPHPSTLYAIEANLRHQGRRGLTLATLRRDEDEHAVMLDTLGALYARGVDVRWDA
VAPARVSASRDADNADNADNRPTPLPVPVSGRSEAALRAQAAALRRYLADHPEAELPAVA
RALATTRTHFEHRAVIVAGEPAALRDGLAAVAEGAPAAHLVRAAAQDGGKIVFVFPGQGS
QWAEMARALLAESEVFRARIETCAEALAAHCEWSLLAVLRGEDGAPPLERVDVLQPVLFA
VMVALAELWRHLGVQPDAVIGHSQGEIAAACVAGALSVADAAAVVARRSQILAALSGRGG
MALVDLPVAEARARLAPYAERLAVAAVNGPRSTVVSGDDDALDELLAALEADAVFTRRVR
VDYASHGPQVERIREPLLAALADLRPRPSALPLMSSVRGEVVDGAELGAEYWYQNLRQTV
RFADVVEALAGDGYRFFVEVSPHPVLLPSVKDTLAAAARPAAAVGSLRRGAGSLAQMTLS
LGELFASGAAVDLGRLCPPAARLSLPTYVFQREPYWVPSAPAARAPGEGAGSGAAVFGPP
IASALGDGAWLWQGELSCERFPYLAEHRVGERVIVPGAAYPALVFDAIAGTPWDGCAEIE
DLELRAALDLTPPLAAAVQLALVPSGAGAAALRVLAREAGDQREREPGDWVVHAAGVLRR
RERDQDAAADAPLDVDAVRARCPERIDGAAHYTTMRAWRLGYGPGFAGVSAVWRGRGEAL
GAVAVSPSGAGGDPGHRLDPRWLDAALQVALALDPAYPGDDPAAAVMPVGWRALRVRELP
RPGDTVWSHVRVREPADDAGRMLADVAIAHADGRPAVTIAGLRLQRLAAAEQRAPLLRRE
WRPAERPAASAAPAPGPWLLVGGGAVGERARARLEAGGHEVVALDPGELAGDPARAVERV
RDSAGGAGAVAGVVHLASLTAEAPAGDASMVAASEPVWASALHLVHALIRQGWRDAPRLW
LVTAGAQRVEGAAPGGVAALLGAPLLGMARTLAYEHPELRCTRLDLAADPADAGAAADAA
DAADADLGASAGADPDALAEALVAELLADGGDDEIALRGRRRFVARLGVGAMGPPVARRE
PAAGRPLRLDLTRERGSALVALERPAPAAGEVELHARALAFDPAGLAPRPDDDARALFFT
CAGRVSALGADVDPAWLGREVLAASPAGAVLGSHLAVPAALLAPLPPAGPAGPAALQLLA
HMLAQHALADVARAAAGERVLVRGAGPVAAAAAQVARQLGLELVADAAIADVADSGGGRG
VDIVLDAAAGAPSEHDAALLAPCGRWLRVSAAPVERPGALPTALFERGRSYAAVDLGALA
EARPQQHAALFQQVAQRLTAAEDPAAAAAPATPISRLVEPGAEPPPAGLASFDLDDPAAQ
LELAGARIRGDASYLLTGGRGGLGLSLARWLFEQGARRLLLAGRSAPSAAAEQLAAELSR
AGAEVVLATVDVADPAAVAQLLADCERPEAPLRGVFHLAGILDDGLIAQQDRARYRRVLA
PKIDGAWHLHRLTRERPLDLFVLYSSVAALLGSPGQTGYAAGNSFMDALSEIRQDAGLPA
LSVAWGPFAEVGLAAAREERGERLHDRGMSSMSTQDSEDALGALLARDEPWVGVVALDVG
RWLDFYPTLGASAYFGQLVGDAAPGAPGDAQQALRARLEATPAPLRAGQMQRLVREQLAR
VLQCRPEAIAAETAFTALGLESLTGLELRNRLEAEVGLRLPATLIWTHGNLASLAGELLA
RLLPPPEVDEASDRAGERDGQPQLAEGTTRQRAAKATASAPAIAPADETESELQERTSAL
SDEELLAELASELGELGDL
>A0A077N6C5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Xenorhabdus bovienii str. feltiae Florida|TrEMBL
MGNNFTGLEVAIIGMAGQFPGADNIRDYWEMLRDGKEGVSRFTNEILKSNGVSEEYYLNK
NYIPAKGVINKPFHFAADYFGINHSDAKKTDPQIRLMIESCWQALKHANIDTETYPGQIG
VYAGASSQWSWFKALNTEFNSSAEQFHVATLNDLSFCTRISYLLNLRGPSITIQTACSTS
LVAVHTACQALQAGECDVALAGGVSITHPHQSGYLYQEGMINSPDGKTRVFDANACGTVF
SNGVGVVVLKRLSDAIEDNDKIYAVIKGSAVNNDGSDKISFTAPSVLGQQNVIRSALDFA
EVTPDQISYIEAHGTGTLLGDPIEISALNAVFKNSQSCAIGSVKSNVGHCDAAAGILSLI
KSALCVYFKTLVPSIHFEKANPKLELENTPFYVNTETKPWHSSDNELICAGVSAFGVGGT
NAHVVLQEFPMRTETVSVEDLEYEELPNRIEFKPAIAAETTDVLHAEVESDSVFVDDEID
IEGLPQHLLKIFQEYFSNQKISQNDNFFDIGASSLDIVQLHEKINNTYSVNLSISDFYRY
TNCQKMTEKLLGMIGNKSQGQPKKSKVTKKRKVLNNKNRTYQDYPEHAIAVVGMSGRFPG
SKNIQEYWNNLLQGKEGISFFTDDELIDAGISAHTLKAKNYIKAKGIVADSLSFDPTAFG
YTARESQYMDPQFRLLHEVTWQVLDDAGYGNPKYRPVTGLFASSGSNHAWLDLLKEEIQD
TTEQFGVALLNDREFLTTRIAYKLNLTGPAVTVQSACSSSALAITLACQSLQINQCDLAL
AGGVSVVTPIKSGYTYAKGMVNSADGHCRPFTQDASGTVFSDGIGMVALKRLDDAIRDND
HIYGVIAGYGVNNDGHEKAGFTAPNADGQAACVKQSLKMAAIQASDVEYLEAHGTATRVG
DEVELEGIKDALGVTEINARDCFIGSVKSNIGHTNTASGVASFIKTLLALKHQKIPPSCH
GTENKHTSLENTRFRLIDVAADWVSHGRVRTAGVSSFGIGGTNVHITVQSIEEQPASSQC
QAELITLSSKSREGLVKTMARLGDFLDEEQHSYSLSDIAYTLQVGRGDYDYRTSLVAENV
EALKEALHSLKDSNTLPEALPDQTSGIVFMFPGQGSQYVNMAKDLYQELEIFKTLLDECH
ERLSSQFSIDLIGLLYSGDSEEDSEKLQNTQITQPVIFAISYSLAKTLELLGIEAKAMIG
HSIGEYVAATMAGVMTLDEGLKLVATRGIIMQECEPGVMLSVAAGRDDLEPFLTDKVALA
TVNSPNSCVIAGSQADIEKVQQRLVDKNFRTRLLKTSHAFHTPMMKPGAEKFKAALAEVN
WQKPTKAYISNVTGQWITPSQANSVDYWVEHLCQAVEFHAGIMTCLEKPGLNVFLEVGPG
RTLSTFVKQIAASDANILTFNMMRHPLEAENDRNYLLKLVGQLWMRGISVNWPLLYQNTH
PKRISLPGYQFAGENMVMGASVLAAKGSEKASETKIQKNQISEWLYTEAWEDISLPDEAT
RSDIRVALCFVPDITWCQPLCNSLKLDEKSIKFVLPADAYTSAENVITLVPGDKRHFGKL
IDELKQDALLPDSVIFAWPLSGQRDLETSWFSVITLIQSWTTSGSMTDFRLLLANTKQPE
HTMLNGLVKVITQEVSKCHPRLVQISPLESIERQCEILTEELLATDERFIVNRTQTGRST
LAYHKLRAGLLKENTLLKNEGVYLITGGLGDLGLLFAEYLIKEYGAKVILSGRRVLPGKH
EWKQLASIDHPEAEILQRLDELSELGKGEVAYYSSNVSDKHEMQVLLDAIEEQYGCLHGI
ICAAGVTRGNSFQGINKLTLEDCTPQIETKVEAYKILAELTENKPLDFCLLCSSIASVLG
GLSFSAYSSVSSFADTFAKQQNSQGKPWISVNWDGWVFERNNSGDPIGSSLDQLLIEPDE
GLKILECALQSPLRGQLIISTGDLDKRFEQWVGGHLKPFKLNEFNHSQRAVVSKAQIVGT
IVSVWQDFLKVTNISRDDNFFELGANSLDMVQVNKRLTDALDMDFSVVDMFSYPTSELLA
DFIVNQYGITHDTGEQAEHSDTLNQHRDPSAQLNQSSTPIDRQIAIVGLAGTFPGAENIH
EFWENLTFGKESVTTFSKEELSEEGIDSGLLENPNYIRAKGVFPNAGEFDAEFFGYTPYE
ARQMDPQVRALHTCCWQALQDARIATKDNRAKIGLYASASGNLQWLAQAMATAEGSAGQY
SAMTVADKDYMSTIVSYKLNLTGPSMVLSTACSSSLVAVNEAVKSLRAGECDIALAGGVS
ITLPIKAGYVFEEGMIHSKDGKCRAFDIQASGTVFGDGVGIVVLKPLKQALADNDNIYAT
IIGTAINNDGGMKVGYTAPSTKGQVEVIQSALRDASVMAESIHFVEAHGTGTTLGDPIEF
NALKQAFSTDKKNYCRIGSVKSNIGHLNSAAGIAGLIKATLAVKNRILPPTLHYARPNKE
IDVTNSPFIVNNQYTELNDTRNPIRAGVSSFGIGGTNVHVVLEEAQVSKDKSFNKKVDNR
LPIVLSAPDDKSLQCYKQQLKTFVENNQQQMSVSDIAYSLMQREPMASQFVASACDYDAL
IKTLSSGEKDNVKVKLGTTKRKVVFLFPGQGAQYVTMGHELYHSNGLFKEWCDKGFTLAD
KYCSIDLKSLFHSRDEDRNLYNTEFAQPLLFIIEYALAQVLKSYGVTPDAMIGHSLGEYV
AAALAKVFSFEDAIKMICARGKLMQSTEDAVMLSVMSSSESVKEILTGSLEIALDNSSDL
CVVAGSDSDISSFESDCEAKSIKTKRLRVNKAFHTRYMEPVLGDYASIIREIAFNKPQIA
FISNVTGKWAETDKVVEYDYWVNHIRQPVRFKESITEVLKEGNCLFIEVGPGHGLSTLAE
NHSDYHANHICISCFDRKNEEINKPSELVQKLGKMALLKIDVNWHAEMADLQPRLVHLPP
TPLRGTKYPTDIKRLQALFSGNKNLGYQADKPEEPVSQSKAGSNPHPKAKRSVIDELSAI
WKLILGVDTIKEDDDFISIGGSSLSAVQVIAKAKSVNLPVNMSMLLSGQTLVQISASLQS
DDETTHKGWQFNEHFSPEMYPGSASCLYSAVREKLKHEHGLTSDDAIMQVVDGSPLLGIG
VQQFENATKIVSKPVNYGTLSGWPSLQECYSFSYDKQFFEDYEAYRHYCESELALGHLVI
VTGSDYYLPFSPSYGLPESEYIKRPLFENIELGDDDIIPHAFVLVGKTPSGYQIYDGSFQ
YFGEITEQEFEKTVIGFKGLDFMQSHEVYNKSRSFMVITVTCAGKFHKDNDLKEQTLNRL
VTDFQTKQAIESNESHLSYYVGLTALDKLIENPGLIASSSNFDLAEIFSRWYQQMLLLRK
FLKISKPEVSTECDHAFSIISEELDKVVACCKNSSDDKTIIDSLLLVKSNLSDIIKNLS
>A0A086K178|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii GAB2-2007-GAL-DOM2|TrEMBL
MAGAVEPVSRLFERVEFSKPAIPFISTVLGRLAVGSELSDALYWSEQITKPVRFREAIHA
ATSGEFSAMQAYIEVGPSRVLAAMGRDCDSGADGTIHEWLCTVDPRSAANPFEAIATLQE
RFAQRLPMDESVRHTWNHSAFPWTVPRHPLIGKEMPTVSAAGGEQVSRYSSRVRLDVLDA
LRDHVILGMPLMPGAAFIDALLAAGRLEHTRIDRRISSSAVIKLSDVSIFSPLLLPESLG
SGVAPGEQGFHPSSLELSVEMKPDGRDHLAEVRSRRIGTTLAAANEEEYEQSHCRGRLAI
SAGTSQLPASTGGQLTDLQRRFYSEAAVDVSQLYATFAELGWQYGKLFRPIAQLFKTDTE
AFAELRLPRPVLPCEEGFIIHPAILDGLFQVAGSLLLTAEKAPAGSVYVPIGVDELAFIP
STSKRDIVWGRVTFAEADDEAKRRQERVVNCTLYDEGGRVLLYVSGLRSRLLRTEVLLSG
TGAAAESNKLWSVEWRASHQQPVAHHEEPVDHSTNWLIAGVHPAVQSQLEEFFLKTMPGA
KVVFCAPSVVATDVRRLLQQEAWNGIIHIGGVTASISEMECLSDVLVLLQAVIDWQANES
SPRPLPAMFLVTRGACCEATENSGLSHSLAPVHSGMRGLFRTAKAELEALWNRFVPLHYI
NIEPSSDKQTVTPEELRQVFSVIQQQGAKAQFIQDQLTQEPSKPLFYESESLLRDGELLL
PRLVPASLEDCGDGNALAEAMTGTIVITGGLGGIGLVLAKWLTGQEARAVVLVSRTGTPS
AEVQRSEDWHLLQSRRQHQTRIVTASCDVGDREQVKLLFRSLRAGSFVCHSTGQVVELPP
IRGIFHAAGVLRDCPIQKQDAETLASVFRPKSQGAWNIHNALEELNMNEGLKVFLMFSSI
ASLVGNPGQANYAAANSSLDALASYRRCRGLAGHSIQWGPWIEQGMAAELGERLERAGFR
GISNKVGVEVTEAVVSQGTTGDFVVACQEFIWPRFVMRYRGCLPAIFEEQTRSVTVRMRD
ERSSRQAAGPEMHQESAFASMAPDELRALIQATVSGAAKQVLGTAEEPPADAPLQALGID
SLGAVEFRNAVQDAFDIRLSATLLFDYPSVQAVSDHLWSMVRAKTAIDTSSRGDDQLASA
AVLQDTGVSIAVVGMACRLPGSVNDLEAFEEMLLTFQDCIQEIPPSRFSIEEVYDPDPDA
KGKIYVREGGFIDGAELFDNRFFGISDAEAREMDPRQRISLEVSYEALGTNAEPIRALSN
I
>A0A655FV79|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MRSLAASYGTAPAGRGPLLGSVKSNIGHAQAAAGGLGLVKVILAAQHAAIPPTLHVDEPS
REIDWEKQGLRLADKLTPWRAVDGWRTAAVSAFGMSGTNSHVIVSMPDTVSAPERGPECG
EV
>A0A1X7AGI6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Parendozoicomonas haliclonae|TrEMBL
MDHPLQLVPVSGHTPAALITQCHNLVAYLEGHEVSLEDLAYTLGVYRSHFVYRLAVCADS
VSDLCQKLNSFLAVYTGEASPEPLPDSCFYGDAHSQKSLSESGMALADRGLTERSLKEVA
RFYVEGNEIAFKQLYPDQTRCRLDLPVYPFQRKRHWVNTELPISDHNKSTGTDNLLFHYE
WVATPLSAPVAGYFPSPISMTGTVADAVVDVSNRQWFQAFDSYRDELDRLTSHYMVAAFV
SLGVSVDTGTCIPSADQLADTLGIVDNQRRLFRLLFKRLVAAGYLKPDDSGENWCWQPSV
SDVMLDEPESVPAEPSPASRLLHATGPKLADVLLGRVKPEQLIFPNNDTSLVNALYRDSA
DNEYISHQIKQVLEQLIETIPAGGELKILEIGAGTGGTTEPLLEYLQSCPGHFSYAFSDI
SPVLLKDAEKRLGHFNGCGGLRLSFTILDIEQDSISDGEQGYDLVIASNVLHATQSIADT
LTHTRALLHDGGWLLLQEAANPGTWIDIVFGLLEGWWKFSDTKLRSDNPLLSPGSWCKQL
ELAGFDQAMTPVPAECPQTLILARAPIKSNDYNSNDHNSNGSVQVENTCLVVQSGQELPS
LQDASASASGKTTDLCWHLPSLTLDTADDPLDLIQPLIRQFIAITQWINDAPAPPRLHVL
CQQAFASKPSEDVQPLLAPILALVRTLASEVPETAGVIVDADQPVDTDWLLMLANSQTSD
IYSLRRKRLFTRGLINDPDDTEVDVSNPLLTAAKGTWLIAGTGGMALLTTRWLARQGIRT
VILFSRHGLSQDQTPALKRLETEYPELKLSVEQIDICDAQAMEQLGQKLISQGDFKGKVQ
GIVHCAGSLDDGVVRHQTAERIAQVLGAKVQGGWNLHRLAEALMPEYVLLFSSAATLSCP
PGLGAYAAGNCFLDALAEYRLVRGEPALALDWGAVKDVGVERVQASNTTMASTLQALDIK
PMTPVQAMDGMTRAFRLQAQQAYGSRVVSPIDPQALGAHGDSLPAVFRTLAAQHIPEVSR
PKSNANPINGQTGLRSLLREQLRAQIRKSVQSVLDEQHQSLLTDQASFQELGMDSLKAVE
LRNQLVKALGQPLSSSVLFDYPSVDALVEHIRPLLAETESVEETVEPENRLQDASDKRTP
HSDAVAIIGMGCRFPGAESPDAFWELLSEGLNTVGELPVDRRRLALDQPVAGPKGHGGYL
NDIDMFDPLFFDIPPSQAASLDPQQRVLLETAWQAIEQAGLAKEQLWNSRTSVFVGLYHH
DYQKKIAEAGVEELDGWTLLGSEHSTMAGRLSYWLGLRGANMPVNTACSSSLVSLHLACQ
GLINGESDLALAGGVSLLLSSYRQIYFDKLGALSSTGQCRPFGQEADGFVPAEGCGVLVL
KRLADAERDNDNILAVIRGSAVNQDGRSQGLTAPNGPAQAQVIQEALDAAALQPTDIDYL
EAHGTGTALGDPIEINALASVFHERSRKTPLQVGSVKSNIGHSEAAAGVAGVIKTVLAMQ
HGQLPASLSCTPVSRQIRWDAIPISVVRHLSGWPETGRPYRAGVSAFGFSGTNAHLILEQ
APARKVVSRTQPALEVRSWQLVLLSARSPESLRAMVEEMLAYCQDLADSEAVTAENLAWN
LAVRRSSFEYRLIVPAENLSDLYEELEQWLAAHSGQQKRCDPLAADETVLWLNLPEAPDA
LRQLVANYRSEQTFMEVLEHWAAFMGIALEGLLLQLSEPAQDSPNRDLAIAGIGCALVAT
WRLWGINGSSLVAEGLALPGILSDDQSLDDAFAMAQQLVDKKTTGRADPHLLKTCSQLVE
NQTVPIMKVDTEGMPSIDSSQLSHSRVVVCVEPLSAQYDLQTCCFSDPGAGLQQWFMSGG
SVNWKAVWQGREGQPLDLPGYPWNRSAYWLHDASKKSVTRSATTSEIKSESLKVYQRVWQ
ALQSQTAADSNIKTDDNSHVIVWPTNDQPGRDVFSAVEQQFQALKSHLVNESLPEVVWVL
TRQGERLPGDISAGSDIASSEQSAIRGFVRGIAQEYPDLTFVLLDIGARDDAAEVIQQLK
QRDEYRQYVLSRSLTRSLTEMAYRRGQFYRPILQESSSSPENNAPLLSGQALITGGLGSL
GLHTALWLVEQGIEQLVLVSRHRPEDPERQQLLEQLQSRLPQTGSLQIELRDIGEPDVLA
NLLATMRSRSSDSIVVYHCAGVSENLPLAELDLQTLRNNMRPKVMGFEALASLPEDLRPD
HIICFSSLASVTGRATQSAYCAANAWLDAGAERLSREGLSCRTISWGPWQAGMATRSRTL
DALSASGIYPLTPHEALGRLSATAATGHSVVADLSEAMRERINFSESQNLDDEPEHSFQG
EDNGFLDQYFQAAEIEKARLLTHWLKEQVLQLMGMEPDAALSEEEGFFALGMDSMMMVSL
ANTISKNLGLTLDAALIISAANLGGLARKLLPLLDKQCDRFKSPRSSPNKDNQATLVEER
CTAAVDPVVILGSSCTLPGGVNDLDQFWQLLAEGRCTREKISPDRWPLEGFYSPDQDRVD
RSYCPYGHFVELPGIEEALFYGISPREAEKMDPQQILLLKNAWLALENACLVPDDLRGER
VGVFLGIGPPEFSHTQRHLRAETDMYSVTGSHISFAAGRLAHSLGLQGPCMAVDTACSST
LTALHLACQALDSGDCDLALVAGVQTIMLPQTYIALCRARAISADGLCKAFADNADGYSR
GEGCGVLVLTRESRADQLAIPAQAKVASTAINHDGAGPGLTVPNSEAQQRLVQQALGKAR
LSEDDIGYLEAHGTGTRLGDPLEVMALAEVFAARRSPLPIGSVKGNIGHLEAGAGMAGLL
KVMAAMRHRQLPPHLHAQTLNRQIPWQDIPVQVCQSLTPWPVDDSGTLYAGISSFGLSGS
NAHVILASA
>A0A2K8RA72|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MTTPNEKLVDALRASLKETERLRKQNQQLTDASREPIAIVGMSCRFPGGVGSPEELWRLV
ADGQDAISGFPTDRGWDIESLYDPDPEREGTFYARGGGFLYDASRFDPGFFGISPREALA
MDPQQRLLLETSWEAFERAGIDPASARGSRTGVFVGASTQAYGAGEYDLPEGVEGHLLTG
TASSVASGRLSYAFGLEGPAATIDTACSSSSVALHLAVQALRQSECSLALAAGATVLSSP
DVFVEFSRQRGLSADGRCKSFAASADGTGWSEGVAVLLVERLSDARRNGHPVLAIVRGSA
VNQDGASNGLTAPNGPSQRRVIRQALENARLTPADVDAVEAHGTGTTLGDPIEAQALIST
YGQERPEGRPLWLGSLKSNIGHTQNVAGIGGVIKMVMAMRHGVLPRTLHVDEPTPHVDWS
AGEVSLLTEARPWPETGGPRRAGVSSFGVSGTNVHTIIEQAPESEPAETSAAPAVTPAVL
PWVLSGRGAAALRAQAERLIAHVEAHDELRPVDVGYALATSRAAFEHRAVVVAEDRAGLL
TGLGALARGESAPGLVEGSVAGGKVAFLFTGQGSQRLGMGRELYDAYPVFAEALDAVCGE
LDAHLERPLRDVLFGSDAEALDRTGFTQPALFAVEVALFRLVEAWGLKADFLSGHSIGEL
AAAHVAGVLSLADAAKLVAARGRLMQELPAGGAMIAVQASEDEVAPLLTERVSIAALNGP
MSVVIAGDEDAAVAIAAGFEAQGRKTKRLTVSHAFHSPRMDGMLDAFREVAEGLTYEAPR
IPIVSNLTGGVVSAEEITTADFWVRHVREAVRFLDGVRTLEAQNVSTFIELGPDGVLTAM
AQDCVTGEDAGFIAALRKDRPEAEALTTAVARAHVRGVAPDWAAYFAGTGAHGVDLPTYA
FQRERFWLEPGAASVGDVASVGLELAGHPLLGAAVPLAESDGLVFTGRLGLDTHPWLAEH
TVRDAVVVPGSAFVELAVRAGDQVGCDLLDELTLHAPLVLSARGGVRLQVTVGAPDGDGR
RSFTVSSRAEDAAADTVWLRNAGGVLASGAPGPSFDLAQWPPTAAEAIEAEALYARLAEA
GLRYGTLFQGVTAAWRRGDELFAEVRLDDDAKPGAEEFAVHPALLDAALHALHGREGARL
TDVWQGVSLYAEGASALRVRIAPAGADTVSVALADATGEPVAAVDALRCRPLPDDLAGDA
DVVRRSLFQLDWVAPQTTSAGPDAATRRIVLGDDPFGLVTAGVAATSAPDLAALGASVEA
GETAAPELVLASFAPVPSVPAPSAPVSGGSDEGVAEAAHRAARRALALVQGWLADERFGD
ARLVIVTRGAMAADAEEGVTDLVHAPLWGLVRSAETENPGRFVLLDVDEAAEAAGAAEAA
GGVGAAEVPATFGDALSDALATGEPELALRAGRPLAPRLIRATAPAAGSGPALAAGSAPV
LGSTSTSDSAPAPNTNSRPAATAFDADGTVLITGGTGALGRLLARHLVAEHGVRHLLLTS
RRGADADGATELAAELRERGAEITLAACDAADRDALAATLAAIPAGHPLTAVVHTAGVLD
DATAAALTPEQLERVLRPKVDAAWNLHELTRDLDLSAFVLFSAIAGTLGGAGQANYAAAN
VFLDALAAHRHAAGLPATSLVWGLWAQSGGITGDLTETDLLRLARSGMGALGDDEGMALF
DAARRTGRTLLIPARLDLAALRSAAGSGPVPALLRGLIRTTGRRTAAGALGAGSSLAQRL
RALSPNERRRTLLELVRGHVATALGHASADAIEARRAFKELGFDSLTAVELRNRLSAATG
LKLPSTIVFDHPNPTVLADHLRAELIGPDIDGAGAEAEQADPALPATTASLADDPIAIVA
MGCRYPGDVRSPEDLWQLVATGSDAVTGFPVNRNWESQWAADGDEAPSEYARAGGFLHDA
DLFDAAFFGISPREALAMDPQQRLLLETSWEVFERAGIDPDALRGRSVGVFVGAAYSGYD
AGLEQAGAEVAGHVMTGNAGSVMSGRIAYALGLEGPAVTVDTACSSSLVALHWAIQALRQ
GECTMALAGGVTVMTTPGHFAEFGRQGGLAADGRCKAFAAEADGTGWGEGVGMLLVERLS
DARRNGHQVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRKALASAGLTSGDVDAVEAHG
TGTTLGDPIEAQALLATYGQDRDAERPLWLGSIKSNIGHAQAAAGVAGIIKMVMAMRHGV
LPRTLHVDQPSPHVDWTTGDIALLTERVEWPETGRARRAAVSSFGISGTNAHTIIEQAPA
TTAEPAVAEAGRDGAGRDGAERDGAGVLPYALSAKGADALRAQAERLYAHLTARPDLEPA
DVAHTLATGRAALDHRAVLVADGRDDLLRGLDTLARGESAPGLVEGTVAEGETAFLFTGQ
GSQRLGMGRELYDAFPVFAEALDAVCDELDAHLERPLKTVVFGDDAEALDRTGFTQPALF
AIEVALFRLVEAWGLKADYLSGHSIGELAAAHVAGVLSLADAAKLVAARGRLMQELPADG
AMIAVQAAEDEVLPLLTDRVSIAALNGPTSVVIAGDEDAALEIAASFEAQGRKTKRLTVS
HAFHSPRMDGMLDAFREVAEGLTYDAPRIPIVSNLIGAVVSAEEITTADFWVRHVREAVR
FLDGVRTLEAQGVTTYIELGPDGVLTAMAQECVTGGNAAFAAALRKDRPEAEALTTAVAR
AYVRGVAPDWAAYFAGTGAHRVDLPTYAFQHRRYWPEEPVASLAAAGVDGWRYQVAWKPL
SLGSAARLSGVWLVVTPAGEAAADVWAHGVVRTLTERGAEVRRLDLADGDREAIAERLRT
AADGGAVAGVLSLLATGDDAEGLLPTAALVQAMGDAAIDAPLWCATRGAVSTGRPGELVD
PARAQVWGLGRVAALELPDRWGGLIDLPETMTDRALSRLAVVLAGAGDEDQIAVRASGVF
GRRLARATARQVAESEGWCAHGTVLVTGGTGALGGQVARWLIDRGAGHVVLAGRRGLDAP
GAAELRDELAASGARITVAACDVADREALAGLLADLPAEFPLTAVVHAAGVLDDGVLESL
TPERFASVLRAKADAALALDELTRDLDLSAFVLFSSTSGTVGAAGQGNYAAANAFLDALA
ERRRAEGLPATSIAWGPWAAGGMAADEALEQRMRRAGMPPMDADLAIDALQRALDLGDAA
VTVADVEWDRFAAGFTAGRPSPLLADLPEVRQAAARSAATAGEAAVVETASALARRLLGL
PEAERHRALLDLVRTHVAEVLGHADVSDISAERAFREIGFDSLTAVELRNGLNAATDLRL
PATLIYDYPTPLALADHLFAELLGGQAVATGGASPVAGAADGDDPIAIVAMSCRFPGGVR
TPEELWRLLVSGTDVISDMPADRGWDLRTLYNPDPDVEGTSYVREGGFLHDAADFDPAFF
GISPREALAMDPQQRLLLETSWEAFERAGIDPATLRGSTAGVFVGTNGQDYLSLLLGDSQ
GLEGHMGTGNAASVISGRLAYTFGLEGPAVTIDTACSSSLVALHSAIQALRGGECSIALA
GGVTVMSTPGVFVDFSRQRGLAEDGRIKAFAAEADGTGWGEGVGMLLVERLSDARRNGHP
VLALVRGTAVNQDGASNGLTAPNGPSQQRVIRQALAGAGLAPSEVDAVEAHGTGTRLGDP
IEAQALLATYGRDRAEGQPLLLGSIKSNIGHTQAAAGVAGIMKMVLAMRHGVLPRTLHVD
QPTPHVDWSAGDIELLTEAREWPETGHPRRAGISSFGFSGTNAHAVLEEAPAADTVEATD
EGGAALPVLLSARTADGLRAQAEQLHGHLTARADLRPADLGYALAVGRSAFEERAALVAE
DRDGLLSGLAALAEGRQTAGLVQGSVAGGRVAFLFTGQGSQRLGMGRELYYAYPVFAEAL
DAVCDELDAHLERPLKTVVFGEDAAVLDRTGFTQPALFAVEVALFRLVEAWGLRADFLSG
HSIGELAAAHVAGVLSLADACRLVAARGRLMQELPAGGAMVAVQASEDEVAPLLGERVSI
AALNGPTSVVIAGDEDAVVEIAASFEAQGRKTKRLTVSHAFHSPRMDGMLDAFREVAEGL
TYEAPRIPIVSNLTGAVVSAEEITTADFWVRHVREAVRFLDGIRTLEARNVTTFIELGPD
GVLTAMAQECVTDAASDAAFVSVLRKDRPEAEALTTAVARAHVRGVAVDWAAFHAGTGAV
RLAPDELAELPTYAFQRQRYWPKVSSLFLGDVAAVGLGEAEHPLLGASAELPSADGMLFT
GRLALSTHPWLADHTIMDTVLLPGTAFVELAVRAGDQVGCEVLEELTLEAPLVLSQDGGV
QLRLWVGAADDTGRRPLELHSRAEHLSAEEPWTRHASGVLASAGAPEASFELSAWPPADA
AEVEIGDRYAELRDVGFAYGPAFQGLRRAWRRGGEVFAEVALDEGTAEEAAAFGLHPALL
DAALHALGLAGLGGTEHEGRLPFAWTGVSLYASGAATLRVRMAAVGGDGVRLEIADATGA
PVAAVDSLVLRPVSAERLQSARTAYHESLYRVEWTTAGLVDAAVDAQWAVLGTDAYGLGA
TAYADLAALGEAVDSGAALPDYVVVPLANQARPGPFSDGAVLEGPGAANQARPAIEDTPE
GRPGVHADGAVLEGPGVANQARPALEDTPEGRPHPHADGAALEAPGAVSPARPALEDRGL
GAEPQVGGRGGIGENPTQAAHDATTQALHLLQTWLADDRFTDSRLVLLTSGAVATEAGEP
VTDLAGAAVRGLLRSAQSENPDRLLLIDVDGDDSQATLPALPALSAALASGEAEVAVRQG
VLKTPRLARAASAAESEPPEWNPDGTVLVTGASGSLGGLFARHLVAERGVRHLLLVSRRG
DQAEGATELAAELAELGATVRWAACDVADRDALAATLATVPAEHPLTAVVHTAGVLDDGV
IGSLTPERVDHVMRPKVDAAWNLHELTRDLDLSAFLLFSSAAGVFGGPGQGNYAAANVFL
DALAQHRAAQGLPATALAWGLWAGGGMGDTLDEADITRMRRAGVPPLPVAEGLRLFDAAL
TVDEASLVPMRLDLAALRNQPAISPLLRGLVRAPARRAVDAVAAGGETGLAGRLAGLSEP
EQERLLLDLVRAQVATVLGYAGAETIGSGRAFKELGFDSLTAVELRNQLNTVTGLRLPAT
LIFDYPDPQVLARHLRTELVGEESAEVHTPVPVAAVTEDEPIAIVGMSCRYPGGVTTPEE
LWQLVIGATDAVSEFPVDRGWDLDALYSDDPDQVGTSYTREGGFLHDAADFDSDFFGINP
REAMAMDPQQRLLLETSWEAFERAGIDPAAVRGSRTGVFAGVMYHDYLTRLTAVPEGLEG
YLGTGGAGSIASGRVAYTFGLEGPAVTIDTACSSSLVALHLAAQALRNGECSMALAGGVT
VMATPDTFIDFSRQQGLSTDGRCKSFAASADGTGWAEGAGMLLVERLSDARRNGHRVLAV
VRGSAINQDGASNGLTAPNGPSQQRVIREALTSARLTTADVDVVEAHGTGTTLGDPIEAQ
ALLATYGRNRPEGQPLWLGSLKSNIGHTQAASGVAGIIKMIMAMRHGVLPQTLHIDEPTP
HVDWSAGDIELLTEARPWPELGRPRRAAISSFGVSGTNAHTIIEQLPAAEEIPATGPAAE
LPTVPWVLSGKSEAAVRGQAERLLTHLGTHSELNTMDIGYSLATGRAALERRAVVIGEDR
DGLLSGLAALARGESAAGLVQGSVADGKVAFLFTGQGSQRLGMGRELYDAYPVFAEALDA
VCDELDAHLERPLKTVLFGEDAEVLDRTGFTQPALFAIEVALFRLVEAWGLRADFLSGHS
IGELAAAHVAGVLSLADAAKLVAARGRLMQELPAGGAMVAVQASEDEVLPLLSERVSIAA
LNGPTSVVIAGDDDAALEIAAGFEAQGRKTKRLTVSHAFHSPRMDGMLDAFREVAEGLTY
EAPRIPIVSNLTGAVVSAEEITAADFWVRHVREAVRFLDGVRTLEAQGVTTYVELGPDGV
LTAMAQECVTGDAAAFVSALRKGRTEPGALTAALAALHTRGLALDWSAYFAGTGARGVEL
PTYAFQRQRFWVENPEEVREAVAAMDSVDARFWEAVEREDLEALAGTLQSEDADADALSS
LGAVLPMLSSWRRRQGERSTVDAWRYQVTWKPVAARAEGTLTGRWLVVAPSDAPADASDG
VLAEGVVRTLSARGAEVQLVEPTAEDRTGLAELLREAVADAPVAGVFALPSLTEGADGLL
RTAALAQALGDVGVDAPLWVATRGAVSTGRADGPVDPWQARVWGLGRVAALELAERWGGL
VDLPETVDDRALSRLVGVLAGGAGEDQVAVRASGVFGRRLTRAAETAATTERGRDWRPGA
GSVLVTGGTGALGGHVARWLIDKGAEHVVLTSRRGLDAPGAAELRDELAASGARVTVAAC
DAADREALAALVAGLPAELPLTAVVHAAGVLDDGVLESLTPERFASVLRAKADAAANLHE
LTRDLDLTAFVLFSSFAGSIGAAGQANYAAANAFLDALAERRRADGLPATSVAWGPWAEG
GMAADDALEQRMRRAGVPPMAADLAIAALQRALDLDETAVTVADIDWERLAPGFTASRPS
PLLLELPEVRTALEAEGLRTATNGGGADESSLAQRLVGVPATERERMLLDLVRSAVADVL
GHSDAEAVEADRAFRDLGFDSLTAVELRNRLNTVTGLRLPPTLVYDYPSSSALAAHLRTE
ILGDESAGTGAAAVAGVPSTTVAVADDPIAIVGMSCRFPGGVRSPEELWRLLVSGQDAVT
GFPADRGWDLEALYDPDSATDNTTYVREGGFLADAGDFDAAFFGISPREALAMDPQQRML
LETSWEAFERAGIDPTTLRGQQVGVFTGTNGQDYMSLVLHSPDGGDGFMGTGNAASVMSG
RVSYALGLEGPAVTVDTACSSSLVALHWAIQALRAGECSLALAGGVTVMSTPGSFVDFSR
QRGLAADGRIKAFAAGADGTGWGEGVGMLLVERLSDARRNGHEVLAVVRGSAINQDGASN
GLTAPNGPSQQRVIRQALAGAGLSPSEVDALEAHGTGTTLGDPIEAQALLATYGQDRPEG
RPLWLGSIKSNIGHTQAAAGVAGVMKMVLALRHGVLPPTLHVDEPTPHVDWSAGELELLT
EAREWPETGRPRRAAVSAFGISGTNAHTLLEQAPEPEESPATAPAVELPTVPWVLSGKSP
AAVRGQAERLLAHLGGGTAPAATDVGYSLATTRAALDHRAVLTADSGDGLLAGLAALARG
ESEVPGLVEGSVSGGKVAFLFTGQGSQRLGMGRELYDAFPAFADALDEVCAHLDAHLERP
LRDVLFGEDAEALDRTGFTQPALFAIEVALFRLVEIWGLKADFLSGHSIGELAAAHVAGV
LSLADAAKLVAARGRLMQELPAGGAMIAVQASEDEVAPLLTERVSIAALNGPTSVVVAGD
EDEAVAIAASFEAQGRKTKRLTVSHAFHSPRMDGMLEAFREVAEGLTYEAPRIPIVSNLT
GEVVSAEEITTADFWVRHVREAVRFLDGVRTLEARGVTTFVELGPDGVLTAMAQDCLAEP
EAAELLPALRKGRPEAEALTGALARLYVRGPAPDWAAFFAGTGARKVALPTYAFQRSRYW
VDVQLSLDEVASAGLGSADHPLLGAAVELPDADAYVFSGRLSLASHTWLADHTVADTAVL
PGSAFVELAVRAGDHVGCALLEELTLDEPLILPERGGVRLRVSVGEPDGDGRRPLAVYSR
DERSDTDRPWTRHAAGVLGSAEAPAGGGAEPLAVWPPADAEAVDTDELYASMARAGLLHG
PAFQSLGRVWRRGEEVFAEVRIAAERQPEAARFALHPALLDGALQPLALGADGAAVARSW
RGVSLYAVGAEALRVRLALTEDGAVSMLAADETGALVASVEALVTGALEVDRIAGATVSD
RHESLFRIDWAPVAAPSEAASAGIAVIGGDELKLSVALETAGFRATVHDDLGSLNAAVEA
GGPVPDTVLVPFPPEPGAAEGGLAAGAHTATHRVLGLLQEWLNGGRPGAARLVVVTRGAV
AAAGDPAVTDLVNAPVWGLLRSAQTENPDQFVLLDVDGEVSYPAIAAALGSGEPELALRA
GAAYAPRLARVEAAPAIGTTKAIDTPEPAKAIDATGSAGRAIDPDGTVLITGATGGLGRL
FARHLATAYGARHLLLTSRSGPAADGMAELVAELAELGARATVVACDAADREALAGLLAG
IPADRPLTAVVHTAGVLDDGVIDMLTPERVDTVLRPKVDAAVNLHELTRDLDLSAFVLFS
AAAGTLGGAGQGGYAAANVFLDALAGHRRATGRTAQSLVWGMWAEERGMGGRLGEADQQR
AARGGVLPLAAEEGLALFDAAHAVADEAVLVPVRLEMATLRAAAATGGLLPLYRGLVRTP
VRRAATGGPAAPEAVAEAGEGTLAQRLAGQSEAQQQRTLLDLVRRQVAGVLGYASKDQVG
AEQAFKELGFDSLTAVELRNRLNAATGLKLTATLVYDYPTPVALARHLRQEVAPEADGPG
VSVLEELERLENSLSSLTSEDLESVMEDEAAHANIAVRLQTLLAKWNDVRRTADDAGAEA
EADAFEEVSDDDLFDFIDKRFGNG
>A0A2K8RFF8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MLRTDLIRPVPELLRANADRFGDKPACSDGHRTVSHAELERRTRRLAGHLAGLRLHPGDR
AMICLGNRVETLESYFGVLRANAIAVPVNPRSTDAELSYLLDDSGARLVLTDAAHADQFD
RLREQIPELRVVVSGDGPLPKGFIAYEPLPDTEPELAARDDLGLDEVAWMLYTSGTTGLP
KGVLSTQRNCLWSLAACYVPVTGLTAEDRVLWPLPLFHSLSHIVCLLAATAVGASTRIVD
GVATADVLEALREERSTFVAGVPTLYHHLIEAARERDFAAPELRVALVGGAVATADLVRS
FESTFGVPLVDAYGSTETCGAIAVNWPTGPRVEGSCGLPVPGLTVRLVDPDTGADVPAGQ
EGEFWVSGPNIMAGYHNQPEATAAALRDGWYRTGDLGRRDKAGFCTVTGRIKELVIRAGE
NIHPGEVEAVLRTVPGVADVAVVGKPHTVLGEVPVAFVVPGPDGFDPSALLATCRERLSY
FKVPEEIYEIARVPRTASGKITRHVLLELPARLRAAGDGQYDSLLRLDWVPQPALPDAPA
GAGTWALLDGDALGLAEGLRAAGVDARMVAEGVGGSVAGLVADSVDGLVADAVTDLVTDS
VDGLVADSVDGLVTDAAGGGGRPAPDVVVVAPPVAGLPEAGQDLVDGLAARLGGWLADDR
LAGTKFVVATTGAVATGTEADAPEPLSAALWGVVRSLQAACPGRLTLVDVDADVDADLDL
DLDTDVERVRAGEGDGDGRGAALRRAVENGHDQAAVRTGVLLVPRLTRVSVPAEPGTAPV
LDPDGLVVITGGDTARGTALARHLVAGYGARNLLLLSANGLPEEAAAALRSELAHDGAQV
SMAVCDPADRAALDSVLDAQDRPVTAAVHIEEPGPERSFDTSLRGMTHLEERTRRADPAL
FVVVTSAAGVLGSPGRPDRAAADQFGEALVRRRRALGLAGLALAWGPLPGEHGTAPVAGA
VPLPEALALFDAALTADQGPLALLRPSTQGLPGGEPVPAVLRHLVDAPSAVPTSDEPAAA
EFRRRLAAESESGRQRTALALVREHAAAALGLASADPVEPDQAFSAFGFTSLTAVALRNR
LNAATGARLAATVVFDHPTPTALARHLVREITGRRSQHAPVRARGVSDEPVAIVAMGCHL
PGEVRTPEDLWRLVSDGRDAIGGFPEDRGWDLAGLFDPDPDAVGKSYVREGGFLADAGGF
DAAFFGISPREALAMDPQQRLLLETAWETFENAGIDPSSLHGTDVGVFSGVMYHDYGADA
GSAAEGLEGHLGVGSAGSVVSGRVAYVLGLTGPAVTVDTACSSSLVALHLAVQAVRTGEC
SLALAGGVAVMSRPTSFIEFSRQRGLAPDGRCKSFAEGADGTNWSEGVGLVLLERLSDAR
RNGHEVLAVIRGTAVNQDGASNGLTAPNGPSQERVIRQALANAGLTVADVDAVEAHGTGT
ALGDPIEAQALLATYGQERSEDQPLWLGSLKSNIGHAQAAAGVAGVIKMVLALRGGVLPK
TLHVEEPTSKVDWASGAVSLLSEAQPWPETGHPRRAGVSSFGVSGTNAHVILEQAPEAVV
PAAEADDVGTPGLVATGGVVPWVLSAKSPSALRAQAERLVSRLELGDAPRAVDVGWSLAT
TRAALEHRAVILATDTESGTVTARALAEGRPDSLLVTGQAAADGKTVFVFPGQGAQWVGM
GAQLLHTSPVFAERLHECAEALAPYTDWSLIDVITGAPDAPSLDRVDVVQPATFAVVVSL
AALWQSTGIHPDAVIGHSQGEIAAACVAGHLTLPTAAKIVTLRSQTIAHHLAGHGGMMSL
AAPADTIDLTNWHGKLWIAAHNGPNATVIAGDTDALHELHTHYTDQGIRARIIPVDYASH
TGHVDTIEDQLDHVLNGVTTSTGTIPWLSTVTGEWIGPNTADGGYWFRNLRQTVQFDTTI
RTLADDGYRTFIEISPHPVLTTAIQETLETTNTPNPTITGTLRRNDDTPTRFLTHLAHLT
THGHTPNWTTLYTHTNPHPTHLPTYPFQHHHYWLPRNTNAGDVSAVGLQDTGHPLTGAVV
SVPDTGGVLLTGQLSVATHPWLADHAVSGTVLLPGAAMAELAIRAGDETATPTLEELVIG
QPMTLPDDGALHVQVLVGGEEGGRRGVRIYSRADSAQEWLEHASGTLATQPDEAAEGGLA
EWPPPGVEPVALDDFYDNLAEAGYEYGPAFRGLKAVWKRDGEVYAEAALPEEQTETAGRF
GIHPALLDAALHASNFCVPPAPGQTLLPFVWNNVRLLAAGATAVRVRARATGPDSFTISL
FDTTGSPVASVDSLVLRAISPEQLAAASSGADRSADSLFTLDWTEHPAAPGSEVSWATLG
DGHADDLDALIAAEDRPDRPEAVVADTTAWATERTGLPERARDLAARALDLVQRWVGQPE
LADVRLVLLTRGAVSVHDTTEVTDPAAAAIWGLVRSAQSEHPGRIALVDTDDVSREALPV
AVASGEPQSALRRGLLWVPRLVRSPQGLAVPAHEHWYLDVSEKGSLENLVLRPDPEATAP
LAPGQVRIEVRAAGQNFRDVLVALGGVAGQEGLGGEGAGVVTEVGPGVEGLAVGDRVMGL
FPRSFGPLATADARTVAPIPEGWSYATAAGVPVAYLTALYGLRDLGDVQPGETVLVHAAA
GGVGMAAVQLARHFGATVYATAHPSKHHVLTALGVPEGHLASSRDLGFASAFPALDVVLN
SLTGEYVDASLGLLGSGGRFVEMGKNDIRDPAAVAEAHPGVGYQAFDLGGDAGPDRIREL
LAELVELFRRGAIEPLPVRHWDVSQAPAAFRWMSQGRHTGKIVLTIPRTLDPNGTVLITG
GTGTLGTTIARHLITHHGARHLLLISRQGPDAPGATELATELTELGATVHIAACDTADRH
HLTTTLANIPSDHPLTAVIHTAGTLDDGVLTALTPERLDTVFRPKVDAVTHLHDLTHDHD
LAPFVVYSSAAGTLGNAGQANYAAANAFLDAFAQWRHARHLPATSLAWGLWSDTSTLTAT
MDAADVRRTRRAGVLGMDNAEALRVFDTGLRSGLPALVAAKVDVTALRAPDAELSPLLRG
LARPVRRTARAAAPAAGGLSGQLAGLSPTGQREFLLNLVRAEAAVVLGHTGPEAIEPTVA
FKEMGFDSLTAVELRNRLNSATGLRLPATLLFDHPTPALLAELFRAELGGDPASAKAAPV
PVRTAADEPIAVVAMSCRLPGGVTDPDGLWDLLLGERDGITDFPRDRGWDLEALYDADPD
HSGTSYVLRGGFLEDAAGFDADFFGISPREALAMDPQQRLFLEACWETFERAGMDPTAVG
GRDIGVFAGVINQDYGVRSGPAPEDLEGYLLTGSATSVASGRVAYVLGLEGPAVTVDTAC
SSSLVAMHWAVQALRQGECSMALAGGSTVMGRPSAFVEFSRQRGLAPDGLCKAFGAGADG
TTFSEGVGVLLLERLSDARRNGHEVLAVIRGTAVNQDGASNGLTAPNGPSQQRVIRQALA
NAGLTAADVDAVEAHGTGTALGDPIEAQALLATYGQERQGDEPVWLGSLKSNTGHTLAAA
GVSSVIKMVLAMRHGTLPRSLHANEPTSEVDWSQGAVSLLTEARPWPVNGHPRRAGISSF
GISGTNAHLILEQAPQPESEDMSRADDGTDTPGLVATGGFVPWTLSARSPAALRAQAQRL
LDHLESGADAHPVDIGWSLATTRALHDHRAVILTDTTTESTETTSALRALASGQPHPRLT
TGHATTHGKTVFVFPGQGAQWAGMGAQLLDTSPVFAARLHECAEALAPYTDWSLIDVITC
APGAPSLDRVDVLQPTTFALMVSLATLWQANGIHPDAVIGHSQGEIAAAHIAGHLTLPTA
AKIITLRSQTIAHHLTGHGAMMSILTTQEWAQEALAPWHGRLWIAAVNGPTSLSISGDPD
ALTEFGKALSKAKVYRWQLPGVDFAGHSGHVDTIKNQLHQALDGVTATPGHIPWMSTVNA
DWTDPTHINADYWYRNLRNTVHFEQGTHALLTQGYRTFIEISTHPVLTTAIQDTTETHPD
TPTTITGTLRRDDGGPDRFLTSLAELSTGGVPVHWPTVYAGTTPSRIPLPTYPFQHQHYW
LAATGHTGDVGSVGLREAAHPLLGAVVSVPDTGGVLLSGRLAPSAQSWLADHMLSGVALL
PGTAIVELAVRAGDETGTPVLEELVLGQPMLLPEDGALQVQVLVGAAEDDGRRAVRVYSR
GEESEPWVEHASGVLSPEPVAPVEVTERQWPPAGAEPVALEGFYDRLAQAGYEYGPVFRG
LTAAWTRDGDVFAEITLGEEQHELAGLFGIHPALLDAALHASNFCPGNEPGAGTYLPFSW
NGVRLHAAGATALRVRVSSTGPDHLSLHATDPHGVPVVTVGSLVLRETTAEQFSSASASS
TADSRFTVEWTEHPLAEHEVSWAELDAVHDNDTWPPVVVADTRTYATEDGELPERARALT
GRVLTAIQRLISDDGLADSRLVLLTHGGMAVHDETEVTDPAAAAVWGLVRSAQAEHPGRV
CEIDTDDRSAEALPAALATAEPQLALRGGTAFVPRLVRVRPGLAVPAAAAWHLDVTEHGT
LENLALVPHPRAEAPLEAGQVRIAVRAAGQNFRDVLIALGMYEAEIGTEGAGVVTEVGPD
VADLAVGDRVMGMLPGSFGPLVVADRRTVVRMPRGWSFTAAAGVPVAYLTALYALRDLGD
VQPGETVLVHAAAGGVGMAAVHLAHHFGATVLATAHPDKHHSLERLGVPAERRASSRDLG
YARTFPAADIVLNSLTGEHIDASLELLGPGGRFIEMGRTDIRDADEVGAAHPDRTYRAFD
LGADAGPDRIQELLAELVGLFERGLIPPLPTRPWDITRAPDAFRWMSQGRHTGKIVLTIP
RALDLDGTVLITGGTGTLGAAITRHLVTQHGVRHLVLTSRQGPDAPGAAELHDELTALGA
RVRITACDIADRGQLATLLGDIPAGHPLTGIVHTAGTLADGTITTLDPDRVDTVFRPKVD
AITHLHELTRHQDLALFAVYSSAAGILGNAGQANYAAANTFLDAFVQRRRAAGLAGLSLA
WGLWAETSNLSAALTTANRDRTPSGVVRPMSTEHALNLFDDALGLGLPLVVPAKLDPGAL
RDEPAPGAVSPLLTGLVRPARRTLRSSAGQFAEGGLAARLAALSEADRHRLLLDLVREHT
ATVLGHTGKDAVDARRAFSEIGVDSLIAVELRNRLSSATGLRLPATVVFDYATPEAMAVH
LRSVVVGDTATPSTSAVAPASAVAPADDPVAIVSMNCRLPGKVTGPEELWDLVFQGRDAI
GPFPTDRGWDLETLFDLDPEAVGKSYVREGGFLTDAGEFDAEFFGISPREALAMDPQQRL
LAETSWELFERAGIDPTSVRGQSIGVFAGVIDQGYFGHSQAPQPELEGYLMTGSTTSVAS
GRVAYLLGLEGPAVTVDTACSSSLVALHLAVQALRAGECSMALAGGVTVIAKPSGFISFS
RQRGLAPDGRSKSFSEGADGTTFSEGIGLVLLERLSDARRNGHEVLAVIRGTAVNQDGAS
NGLTAPNGPSQQRVIRQALANAGLTAADVDAVEAHGTGTALGDPIEAQALLATYGQERAE
DQPLWLGSLKSNIGHTQAAAGISGIIKMVLAMRHGTLPQSLHADEPTTKVDWASGAVSLL
SEARPWPETGRPRRAGISSFGISGTNAHVILEQEPEAVVPAAEADDTGTPGLVATGGVVP
WVLSAKTPSALRAQAERLVRRLELGDAPRAVDVGWSLATTRAALEHRAVILATDTEGGVA
TARALAEGRPDPLLITGQTTANGKTVFVFPGQGAQWAGMGAQLLHTSPVFAERLHECAAA
LAPYTDWSLIDVITGTPDAPSLDRVDVVQPATFAVVVSLAALWQSIGIHPDAVIGHSQGE
IAAACVAGHLTLPTAAKIITLRSQTIAHHLAGHGGMMSLAAPADTIDLTHWHGKLWIAAH
NGPNATVIAGDTDALHELHTHYTDQGIRARIIPVDYASHTGHVDTIEDQLHQTLADTTTQ
PGTIPWLSTVTGQWTEPHTADGDYWYRNLRQTVRFDTTIRTLADDGYRTFIEISPHPVLT
TAIQETLEANQTPHTTITGTLRRNDDTPTRFLTHLAHLTTHGHTPNWTTLYTHTNPHPTH
LPTYPFQHHHYWLQPSEVPEAVADGVFWDAVERGDLASLADSLGVEEKTLEPVLPGLTSW
RRRNQDQSTVDSWSYRIAWDPVAAGEPPSLPGAWLVAVPAPQANDDSVMGLVTALAEHGA
EPVVVEVDTVDQAELTACLRERMADPGDEYAGVVSLLAWDERSCEPGTLSRGVAATVALM
QAVEEIGLAAPLWCLTRGAVAVREPSEVTSEFQPLVWGMGVVQGLDQPTTWGGIVDLPQT
PDETALARLCSVLAGVDAEDQVAVRASGVFARRMRREPVTSAPVWRPRDTVLITGGTGGL
GSYVARWAAGHGARHLVLLSRQGAQAPGAAELEAELTALGADVTIAACDVTDREQLAAVL
AELPDGAPLSAVVHAAGLALPEKPLSKMTLAEFADIGRAKIAGARHLDNLLWDRELDAFV
LFSSGAAAWGSGGQSAYAAGNAYLDGLAQRRRARGLAATSVAWGAWGGGLGTIDEMMGAQ
WRRTGLMTMDPRLAALAMAHTVGGGAVHGVVADIDWERFAPGYTMARFRPLLRGLPDVID
LLTEDTSEDGAGQTELIARLAGLTPEEQERLLTELVQAEAAAVLGHANADATGDRPFSEI
GFDSLTAVELRNRLNAATGLRLPATMVFDHPRPSVLARRIRTELGEADTSSVDSVLAELE
RLEAHLAALPKEKIERARITSRLQRMTTKVAEIEAVGAGGETVTERLDTASADDVFAFID
QEFGVD
>A0A2K8QYZ3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MSENSLVRDGHIAVIGMACRVPGASTPDEFRQLLRNGESAITRIPADRYADELRDAGIRF
GGFVETAAEFDPEFFGISPREALAMDPQQRLALELCWEALENAGLLPAHLEGSRTGVFIG
AIADDYATLVHRRDPAAITQHTLTGLNRGIIANRVSYALGLRGPSVAVDTGQSSSLAAVH
LACESLRRGETETAVAGGVQLNLAPDSFIAASRFGALSPDGRSYTFDARANGYVRGEGGG
LVVLKRLQDALRDGDPVLCVIRGSEANNDGGGDSLTTPAAHGQEAMLRAAYERAGVDPAK
VQYVELHGTGTKVGDPVEAEALGAVLGARRADDAPLRVGSVKTNVGHLEGAAGITGLIKT
VLSLAHRELFPTLNHETPNPAIPLDTLGLTVQTSLDTWATEADAPRLAGVSSFGMGGTNV
HMVLEQAPAENPTPAPAPALNPAPERPTAPDAVPWVLSARGEGALRAQARRLRSFVAERP
ELGAVDVGYSLALTRSAFGHRAAVVGRDREELLRGLDDLAAGMVPGTATSGGGTAFLFTG
QGAQRLGMGRELYGAFPVFAVAFDAVCAELDRHVDGSVRDVVFGGDAEALDRTVFTQTGL
FALEVALFRLVESWGVVPDFLVGHSVGELAAAYVAGVFSLADACALVAARGRLMQALPEG
GAMVSLKAAEADVTRHLVGYEDRVSVAAVNGPVATVISGEESAVLAVAEAVGVKSKRLSV
SHAFHSPLMEGMLAEFAEVAGRIGYSAPRLALVSNVSGEAAGEEVCSAEYWVRHVRQAVR
FADGMRFLEGQGVTRYVELGPAGVLSAMGRECLSESAAAFVPLLRKDRDEAEALLSGVAQ
VHAHGGEVDWAAVFAGRGAHRVQLPTYAFQRQRYWLDTDLHGTEDAATDEPLSWRQEFAA
LTDAAERERVALELVRTHTAWVLGSPGPDAVDPEKIFKELGFDSLMSVELCNLLSTATGT
RLAGTVLFDHPTPLALSRHVQHVAVGSRPDVAPRPAATRPVATGHDDPIAIVAMSCRLPG
GVRTPEQLWQLVSEGRDAIAGFPANRGWDLEGLYDPDPARHGTSYVREGGFLYEADQFDP
AFFGISPREAQAMDPQQRLLMETAWEAFERAGIDPTTLKGSDAGVFVGAMPQDYGPRMDE
ASEGFEGYLLTGGTTSVASGRIAYTWGLEGPAITVDTACSSSLVALHMAVRSLRQGECSL
ALAGGATVMSSPGIFVELSRQKALSPDGRCKAFSSDADGTGWGEGVGMVLLERLSDARRN
GHRVLALVRGSATNQDGASNGLTAPSGPAQQRVIRKALADAGLTAADVDAVEAHGTGTSL
GDPIEAGALLATYGQEHAEDRPLWLGSLKSNIGHPQAAAGVAGVIKMVMALRHGVLPKTL
HVHEPSPHVDWSSGAVELLTEARPWPEPEAARPRRAGVSSFGISGTNAHAILEQAPAEPA
TVHDEPHPAAPGLPVLPWVLTGCTQQALRTRAEQLRDRLADHPGTDLAALGHALATTRTA
FGHRAVILGRDRERLLDGLGALARDTPAPQVVQGTADSRRKTVFVFPGQGSQWIGMALPL
WDASPVFAERLEECADALEPFLDWSLRAVLRGEPGAPSLSRIDVVQPALFAVMVSLAALW
RSYGVEPAAVVGHSQGEIAAAYVAGGLSLQDAAKVVARRSQAWAELSGKGGMLSVLASAG
AVAERLRPWNERLGIAAVNSPGTVTVSGDPEALDAFMAELAADGVKSRRVPGVDTAGHSP
QVDGLRERLLREVAGVRPRASRIAYYSTVTGGPLDTAELDTDYWYRNMREPVDFEGATRA
LLADGHTAFVECSPHPMLAMSLQQTVEDAGGNAAVIGTLRRDEGGPERFAGSFAEAYVQG
VEPSWDTVFAGGQGHGELGVELPTYPFQRQRHWLDKPVAAGDVAAAGLDAADHPLLGAAV
PLAGADGHLFTGRISAQDHPWLTERTGPDAAVLPGSALAELAIRAGDQVGCDRIEELSLD
APLVLPEKGAAVIQVRVGAPDDGGSRALSVHARAEDADSDEPWTRYATAVLATGAHAVDI
GLAAWPPADAVPVETARGVGAVWRLGADLYAEVGLTEAEEADAERYGLHPVLLESALDAV
ETPGDGGGSRLASSWRGAVLHATGATALRVRLTPTGPDTYAVAAADLDGAPVVSVERLVV
RAVDTPGPIGGRSALHPSLFRLEWPTAPVAPAAADTAAAPATWAVLGDDPLGLSVAVDAV
PYDETAEVPDAVLVPCAAESRADVAQAAHEATHRVLALIQRWISDERLAPSRLVFVTRGA
VAAVPGEEVPDVAHGAVWGLVRSAQSEHPGRFTLVDLDTDPESATALPVAVASGEPQCAV
RDGLVRVPRLGRVARGTAAAEATATTGAAGAATRIASATEVTGTGLAGVTGSGASGTAGV
AATGVAGAAAAKEAGVIGTAAAAAKAVEGAATRTAGLADGRRPMDPEGTVLITGATGTLG
GLVARHLVGEHGARHLLLVSRRGPAADGMGELRSELAELGATVTVAACDAADREALAGLL
GAIPDAHPLTAVIHAAGVLDDGVVDALDPERLDRVLRPKVDAAWNLHELTADHDLAAFVL
YSSVVATIGNAGQANYAAANAFLDSLAQHRAARGLAAQSLAWGLWEQRSGMSGHLADADV
RRMARSGIRPLPSAEGMELFDAARSAGDATLVPVRLDLAELRGRAASGTPGQDAVPAYLR
GLVRMPVRRVVRAGGGGGGAAEADENSFGRRLAALAAADRNPFLLDLVREHAAAVLGLAA
PDDIEATRAFREVGFDSLTAVELRNRLGAATGLRLPTTLLFDYPTPAVLVDHLRREALSE
RPEAAAVVAAVRPADDDPIAIVAMSCRLPGGVRGPEELWELVADGRDVISTFPTDRGWNV
EELYDPNPDTPGRSYAKEGGFLYDAYDFDPEFFGISPREALAMDPQQRLLLETSWEALER
AGIDPHSTKGTPAGVFIGSTGQDYASRLGEIPEDMEGYLLTGKAASVVSGRIAYSLGWEG
PALTIDTACSSSLVAIHQAAQALRQGECSMALAGGTTMMSTPSLFIEFSRQRGLAPDGRS
KAFSSDTDGTSWGEGVSMVLLERLSDARANGHEVLALVRGSAVNQDGASNGLTAPNGPSQ
QRVIRQALANAGLSAADVDAVEAHGTGTTLGDPIEAQAILATYGQDRQAEQPLRLGALKS
NIGHTQGAAGGAGVIKMVMAMRHGLLPRTLHVKEPTPHVDWTSGAVELLTEAREWPTGER
VRRAGVSAFGISGTNAHVILEEPPADPAAEPEPELSVHTDVVPWVLSARGEGALRAQAER
LRSFVAERPELGAVDVGYSLALTRSAFGHRAVVVGRDREELLSGLERLATGVTPGTVADA
EGRTAFLFTGQGAQRLGMGRELYGAFPVFAVAFDAVCAELDRHVDGSVRDVVFGGDAVAL
DRTVFTQTGLFALEVALFRLVESWGVVPDFLVGHSVGELAAAYVAGVFSLADACALVAAR
GRLMQALPEGGAMVSLKAAEADVTRHLVGYEDRVSVAAVNGPVATVISGEESAVLAVAEA
VGAKSKRLSVSHAFHSPLMEGMLAEFAEVAAGISYATPHIALVSNVTGEAAGEEVCSAEY
WVRHVRQAVRFGDGIRFLEGQGVTRYVELGPAGVLSAMGQECVSESAAAFVPLLRKDRDE
AEALLSGVAQVHAHGGEVDWAAVFAGRGAHRVQLPTYAFQRQRYWFDPATPGTPTAAATD
ASSVEARFWEAVEHEDLEALTTTLEIDEQTRLGELLPALSSWRRGQSDRATVDSWRYRIT
WSPAAIGERTAPLSGTWWVAVPEGRADSARVAAVVAALGRRGARVVPLTVATTGRDAVRD
AGRDVLAERLRREADTGGTPAGVLSLLAFDDGPHPEHTALTTGLALNVGLVQALGDAGIA
APLWLATTGAVSVSGSDPLGSPAQAATWGLGRVVALEHPQRWGGLVDLPGDLDERSADRL
CAALSGIVGDSGPEDQLALRDAGVFVRRLVRAPLRTPGRESWKPHGTVLITGGTGGLGAQ
IARWLVRSGAEHLVLTSRRGTAAPGAAELREELIALGEGGVRVTVAACDVRDRGEVAALL
GRITSGGEPVRAVFHAAGVVEFSQLADSTVADFAEMADGKVLGATHLDALLDQDHLEAFV
LFSSIAATWGSGGQSAYAAANAHLDALAEHREARGLPATSVAWGPWADHGMIEHGEVAEH
LSRRGLPAMEPRLAVAALSEALHTGETSLVLADVRWDRFVPGFTAARHRPLIGELPEVRD
ALATTAAPDSTGPDDVADTFLAGLAGLPGEDLDRALRDLVHAQAAAVLGHSSSDAVAGGR
PFKELGFDSLTAVELRNRLAAVTGLDLPATLVFDYPAPVALAEYLRGELPSAHPADARTL
FDDLDRWESALPELLTDDGVRERLTGRLNDLMAKLGGTPGEHTGGPSPDTGLLSATADEV
FDFIDNEFGAS
>A0A2K8RGY3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MKGSDGTSPSTTDAPIAVVGLSCRLPGAPDPATFRQLLRDGADAITEAPEGRWGAGADTG
TDRDTGTGTVATRRGGFLDRDRIDHFDAAFFGISPREAAAMDPQQRLTLELTWEALEDAG
IIPDRLRDSRTGVYIGVIADDYATLIRRGGSAAIDRHSFTGLHRGIIANRVSHHLGLRGP
SLTLDAGQASSLAAIHLACESIRRGETSIAIAGGVHLNLAPESDVTAARFGALSPDGVTY
AFDARANGFVRGEGGGVVVLKPLADALADGDPVYCVIRGSALNNDGGGDHLATPHQAAQE
DLLRRAYQQAGVDPADVQYVELHGTGTKVGDPVEAAALGTVLGAARPTGAPLRVGSAKTN
VGHLEGAAGVVGFIKTALGLKHGELFPSLNFRTPNPDIPLDQLNLRVQTTSEPWTADPDT
PDTRKPLTAGVSSFGVGGTNCHVVLSGAPEPAVAPDAVESAPEGASGRIPWVVSGRSEAA
LPAQAGRLASYAEERPELSAEDIGLSLATTRSAFEHRAVVLADDRGGLVGGVAALAEGRD
AAGVVRGVVAGADGRAVLVFPGQGSQWVGMAAGLLESSPVFAQRVDECAAALAPFVDWSL
VDVLRGGEGAAAALERADVVQPALFAVMVSLAELWRSYGVEPAAVVGHSLGEVAAACVAG
ALSLEDATRVVALWSKAQRALSGRGAMASVSLPVGEVRERLVAWGGRLSVAAVNGPSAVV
VSGAADALDELLAWCEAEEVWARRISVDYASHCAYVEDIEGELLRELSGISPRSSSVPFY
STVTGGTLDTAGLDAGYWYRNLRHTVRFEETVRALLTDGFQVFIEASAHPVLTMGVEQTA
EDHGTRVTAVGSLRRDEGGLSRFLTSVAEAYVGGAAVDWARMFAGMGARRVELPTYAFQR
RRHWLDVQALPQPSPHIEADAIDPRGGENHTSATDTASLLRTRLVALNDLQQGEMLADLV
CDQVATALGYEGREAVDLGRTFQALGFDSVGAVDFRNRLNTATGLRLPTTLLFDHPTPQA
LVRHLRDALLGDDGRETAASMPVGAVLDEPIAIVGMSCRYPGGVRSPEELWQLIAAGGDA
IGTFPADRGWDLSGLYDSDPGRARTTYTREGGFLYDAGDFDADFFGISPREALAMDPQQR
LLLETSWEVFERAGIDPAGREKSRTGVFVGAMAQDYGPRMHDASDELQGYLLTGNTVSVT
SGRISYAMGFEGPAMTVDTACSSSLVALHLAVQSLRQGECALALAGGVTVMSMPGLFVEF
GRQQGLAPDGRCKPFASAADGTGFAEGAGMLLLERLSDARRNGHQVLAVVRGSAINQDGA
SNGLTAPNGPSQQRVIRAALANARLSPADVDVVEAHGTGTALGDPIEAEALLATYGRERG
AEDRPLWLGSVKSNIGHTQAAAGVAGVMKMVLAMRHGMLPKSLHVDEPSPHVDWSAGAVE
LLTDAVEWPETARPRRAGVSSFGISGTNAHVLVEQAPAELGVVEPVDEGREAPASVPWVV
SAKSEGALRAQAERLLSAVSGGMAAEASVVDVASSLVTTRSAFEHRAVVLAGDHQGFMAG
LEAVVGGVPAAGVVRGSVVLGKSAVLFSGQGSQRVGMGCELYEAFPVFAEAFDEVCGRFD
GLLERSLREVIGGDVEGLDETAFTQCGLFAVEVALFRLVESWGVRSDFVAGHSIGELVAA
YVAGVLSLDDACVLVAARGRLMQALPSGGVMVSVQAAEADVLPLLAGCEAEVSVAAVNGP
RSTVISGVEDAVMEVAGLLEAEGVKTKRLRVSHAFHSPLMEPMLAEFRQVAEGLSYAPPR
IPVVSNVTGQVADVEALCSAEYWVRHVREAVRFADGVRSLADAGVTTFLELGPDGVLSGM
GQECVSDEVFASALRDGRGEVASIQEALAEIYVRGRQVDWSAALAPACPRRVELPTYAFQ
RERFWLEPVRTGTAPAAPAADRWSHRVSWSPVSDVAGALTGTWLVAVPAGLAGDEWVVAC
VAALAGRGALPVVVELEHDDADRAVMADRLRGALDEADVSGAGGVLSLLALAEGRHGEYG
AVPLGVALTLSLLQAVGDAGVGGRVWCVTRGAVAVGGSESPLSVDQAAVWGLGRVAGLEA
PERWGGLVDLPEVWDARMADRLVDVVSGRSGEVEVAVRASGVFARRIVRASVGGGGVGGW
VPSGTVLVTGGTGALGGHVARWLAGSGAEHLLLVSRRGLGAEGVDELCAELRESGVRVTV
VACDVGDREALAGVLARVPGEFPLTAVVHAAGVLDDGVLDGLSVGRFEGVLRAKSEAAWH
LHELTCELGLSAFVLFSSFSGVVGAAGQANYAAANAVLDALAEWRRGAGLPATSVAWGPW
ADNGMAEGVADRWRRHGLPAMDPESAVAALEKSVNHPAAASLILADVEWDTLARTMADTR
SRRLLNDLMAHGSSDASHEETTDDGSLRRRLAGLGTAEQDRVLLELVRSHVAAVLGHRRP
EAIDADRAFKELGFDSLAAVTLRNRLNAATRLSLPSTLLFDHPTVTALVKLLRTEVLGLR
NGADAAVPAAVAIGDEPVAIVAMSCRFPGEVRTPEDLWQLLLAGREVLTEFPADRGWDLD
TLYGPDPDEHGKSYVREGGFLEGAGDFDPKFFGISPREAVAMDPQQRLLLETSWEAFERA
GIDPTLLRGSRIGVFVGSNGQDYGTSLRQAPSEHVEGHLVTSSAASVVSGRISYTFGFEG
PAVTVDTACSSSLVALHLAAQSLRLGECSLALAGGVTIMSTPELFVEFSRQRGLAADGRC
KAFAAAADGTGWGEGAGLLLLERLSDARRNGHRILAVVRGSAVNQDGASNGLTAPSGPSQ
QRVIRAALANAGLSAADVDVVEAHGTGTTLGDPIEAQALLATYGQERPEERPLRLGSIKS
NIGHTQAAAGVAGIIKSVLAMRHGVLPRTLHIDEPSPHVDWSAGAVELLTAPIAWPETGR
PRRAGVSSFGVSGTNAHVILEQGPLEPDAATETTSEPAVVPWVVSARSDAGLRDQAARLL
AMVGDEAGPAPVDVGLSLVTTRALFERRAVVLGGDRTVLINGLSALAEGRETAGLVHGVA
SGPSDRVAFVFPGQGSQWVGMAAGLLESSPVFAERVGECAAALAPFVDWSLGDVLRGGEG
AAEALERVDVVQPALFAVMVSLAELWRSYGVEPAAVIGHSQGEIAAACVAGALSLEDAAR
VVALRSRALRALSGRGGMVSVSLPVEAVRERLARWGERLSVAAVNGPSAVVVSGDADALD
ELLAACEAEGIRGRRIPVDYASHCAHVEAIEDELQQALAGIAPRSSSVPFYSTVSASVLD
TQELDAGYWYRNLRRTVRFEETVRALLADGFDTFIEASAHPVLTMGVEQTAQDHGTHITA
VGSLRRDEGGLDRFATSLAEAYVGGAAVDWSVMFAGTGARRVDLPTYAFQHQRYWVQPSA
ATGDVSSAGLVSADHPLLGAATALPDSDGWLLTGRLSLRTHPWLAEHAVLGRALLPASAF
VELALRAGDATGCDRVEELTLEAPLVLHEQGAVQIQLTVGAADESGARPLRVYARAEDAA
DRPWTRHASGTLIHSEARGEADSPATAPNPAADLSVWPPTGAEAVDTAGFYERLADAGVA
YGPVFRGVRAVWRRGDELFAEVVLPEEAHGEVPRFGIHPALLDTALQPGLAPLSGDADGI
RLPFLWSGVSLHATGASTLRVRLSRKGTDTLSALVADPAGTPVATVDALVARPVTEEQFT
AATAEPGDDRPERATVVRRALAQVAPGAEEASLRQRLLSVAGDAERERMVLRMVQDQAAT
VLGYSAPDAVEPEISFKEHGFDSLTAVELRNRLNVATGERLPATLVFDYPTPAALAEYLR
TELLGLREGDVPSVPTPVTRAEPDDDPIAIVAMGCRLPGGVHSPEDLWDLLTEGRDAISG
FPEDRGWELDGLYDPDPEVPGKTYARHGGFVDGAGEFDAAFFGISPREAVAMDPQHRLLL
ETSWETFERAGIDPASLRGSQTGVFVGAGSHGYGAGPIRPASGVEGYLLTGNALSVTSGR
LAYAFGFEGPAVAVDTACSSSLVALHLAAQSLRQGECSLALAGGTAVMSTPWTFVGFSRQ
RGLAPDGRCKPFSAAADGFGPAEGVGVLLLERLSDARRNGHQVLAVVRGTAVNQDGASNG
LTAPNGPSQQRVIRAALANAGLSAADVDVVEAHGTGTTLGDPIEAQALLATYGKGRPEAR
PLLLGSVKSNIGHTQAAAGVAGVIKMVLGMRHGLLPRTLHLDEPSPHVDWSTGGVRLLTD
DMPWPETGRPRRAAVSAFGMSGTNAHAVLEQAPFEEAPSPGVDDDAPAGELPEITPWVIS
GRSDTAVEAQAQRLLTHMRERRELSPTDIGLSLTATRSVFEHRAVVLAGDGDGLMNGLGA
LAEGHAAPGVVRGTAAARDHAVLVFPGQGWQWVGMAAGLLESSPVFAERIGECAAALAPF
VEWSLVDVLGDAAALERVDVVQPVLWAVMVSLAEVWRSYGVEPAAVIGHSQGEIAAACVA
GALSLEDAAKVVALRSKALRALSGRGGMVSVPLPVEEVRERLAMWGERLSVAAVNGPSTV
VVSGDADALDELLALYEVEGIRARRVPVDYASHCAHVEAIEDELRQMLAGIGPRPSSVPF
YSTVTGGVLDTTALDAGYWYRNLRQTVRFDETVRALLSDGFQVFIEASAHPVLTMGVEQT
AEDQGVRVTAVGSLRRDEGGLERFLTSLAEAYVGGASVDWAGLFIGTGAERVDLPTYAFQ
RTHFWLESETAEAGDVSSVGLDSAGHPLLGAAVPLPGSDGFLLTGRLSLRTHPWLADHAV
LGRAILPGTAFVELATRAGDAVGCDRLEELTLEAPLVLPDEGAVQVQLVVNGPAQDGQRE
FSVYARRDDAPNASWMCHAKGMLAPASGAVARTTDPANLITWPPPGAEVVETAGFYEDVA
ATGLAYGPVFRGLRAVWRKGDEVFAEVALPEESRADAARFGLHPALLDTALHAWLVCAAA
KKGGAADGIRLPFVWSGVSLYATGATSLRVRLARAGADGMSVLVADAAGTPVATADALVT
RPVSEAQLAASTDDGESLYRVEWVATPATDPAPAATLATDRCAVAGPDAFGLARALKAAD
GSVEEHADLAALEAHVRSGAPTPDLVFVTMSSGPGEDIVPATRTVAHRTLDLVRGWLAED
WFAGARLVFVTRGALATEDGADPRDLAAAPVWGLVRSAQAEHPDRFVLLDVDGGEPSLAV
VHQAVSTGEPQLAVRGAEVLVPRLVPGAAKGVLTPADGAEAWRLEASGTGTLEGLTLATA
TDATRELGEHEVRVAVRATGLNFRDVLISLGMYPDEAMMGGEGAGVVVATGPGVTSLAVG
DRVMGLWSGGFGPLAVVDQRTLVRIPDGWSFTEAASVPIVFVTALYALRELAGVRRGESL
LVHAAAGGVGMAAVRLARAWGVEVFATASETKWDVLRDLGLDEAHIASSRTVEFERRFRD
SSAGRGVDVVLDSLSGEFVDASLRLLGEGGRFIEMGKTDVRSADAVAAAHPGVLYRAFDL
AEAGPERIGEMLAEIVALFERGVLEPLPTRVWDVRRAPEAFRFMSQARHVGKLVLSVPAA
LDPEGTVLITGAGGVLGGIIARHLVAERGIHRLLLVGRRGRAAESLAGLEAELTALGASV
TIAACDVADREALADLLAELPDGHGLTGVVHAAGILDDGTVASLTPERLDAVLRAKVDGA
WHLHELTRRFDVAMFALFSSTAGVLGSAGQANYAAANTFLDGLAQRRRAMGLPGVSLAWG
MWAERTGMTEHLGQADLSRMTRVGVVPFPSEEGLRLFDTAGRLAEGVVVPARLDLGHLAA
AADTTPVPPLLNGLVRRPAPPRRASAQDDPGSKEAPLARRLAGLGQGERRRTLLRLVQEH
AATVLGHGTPSSVVTDRGFLELGFDSLTAVELRNRLNAATGLRLPATLIFDYPTPAALAG
HLGEEIAPVAVGGQSDMAAELDRLEAALLGTDTAADDATRAMVTGRLKRLLSRWDGDRGG
PAPNGAANAPSSEDPATASGDTATANGSGDTAPATAPGGPDDVADHLETAAADELFAFID
QEFGSS
>A0A2K8R1Y3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MEFGAFLDRVDHFDADFFGISPREAGAMDPQQRLMLELGWETLEDAGLTPARIAQGRTGV
FVGAINDDYATLLRRHGDSAVTHHTLTGLQRGMIANRLSYLLGTRGPSMVVDSGQSSSLV
AVHTATQSLRSGECDTALAGGVHLNLAYDGALSAARFGGLSPDGRCFAFDARANGFVRGE
GGGLVLLKPLAHALADGDRIHGVLRGGAVNNDGGGDTLTTPSRTAQAEVLRQAYAAAGVG
PDEVQYVELHGTGTAVGDPIEAAALAEVIGAARTKDRPLLVGSAKTNVGHLEGAAGITGL
IKVLLSLEAAHLPPSLNFRSPNPAIPLAEWHLRVQTGLSAWPRPDAPLIAGVSSFGVGGT
NAHVVVEQAPVARPAKGAADVPQGMGRDMGRDVAQDIGQDVGRDVAEGVAVAGARGDEVR
VPLPWVVSGRSAAGVRAQAARLREFAADGQSSPADIGWSLAEHRTALEHRAVVVAGDREG
FLAGLDALASGEPFAHVVDGVAAEPVPGPVFVFPGQGSQWVGMAAELLDVSPVFAESIDR
CARALAPHTDWALLDVLRETEDGAALERAEVLQPALWAVMVSLTRVWRSLGVVPSAVVGH
SQGEIAAACAAGALSLEDGARLIAVRSRLAEALIGRGGLVSIGASAERTAELFADRDDVW
LAAVNGPGATVVGGDLEGLAEVTAGAEATGLRHRAVATAYASHTPHVEAIREEFLRLAAP
IAPRAGDVPMYSTVTTAPIAGEALDAEYWYRNLREQVRFHDTVQNLIADGNSLFLESSSH
PVLTTAVQETGGLAVGTLRRGEGGTRRLLLSLAQLWVHGAAPDWAKVFAGTGARRTELPG
RAFQRRRHWFDTTATRAATDAAPEATGGTEAPGATGAPGTPGASGLDVAHQVRAQAAAVL
GHTTAAELDTGRTFKDLGFDSISLSDLCSRVNTALGTRLSPAALFSHPTPARLAEHLATT
GPAPFDRPPEPATATTADEPIAIIAMSCRLPGGVGSPEDLWRLVADGRDAISPFPDDRGW
DLERLHGTEGAGSSFAQGGGFIDGATDFDARFFGISPREALAMDPQQRLLLETSWELLER
AGIDPGALRATRTGVFVGTMDQEYGPRLHEAPEAVDGYLLTGKTASVASGRIAYLLGLTG
PAITLDTACSSSLVALHLAVQSLRRGESSLALVGGVTVLNTPGIFTEFSRQGGLARDGRC
KAFAAGADGTGMAEGVGMLLVERLSDAHRNGHRVLGVIRGTAVNQDGASNGLTAPNGLSQ
EQVVRQALADAGVAASDVDVVEAHGTGTALGDPIEAQALLATYGRNRPAERPALLGSVKS
NIGHTQAAAGVAGVIKTIMAMRHGVVPATLHVDEPTPHVDWARGGVELVTEGRPWPEAGR
ARRAGVSSFGISGTNAHVVLEEAPPTAVPSVEVRPATSAIRVEGELPWVVSGRSPAALRA
QAARLRAFAGVCDATPSDIGWALATRRAALEHRAVVVAGDRDEFLAGLDALASGEPADQV
IGGAVRGAPGAGPVFVFPGQGSQWVGMAAELLDSAPVFAESIDRCAQALAPHIDWDLLDV
LRATGDDTALERVDVVQPALWAVMVSLARVWRAWGVEPSAVVGHSQGEIAAACVAGVLSL
EDGARLVALRSRVIARELAGHGGMVSLATSADRTHELLTGRDDIWIAAVNGPGATVIAGS
PSGLAEITAHAEAMGVRARTIPVDYASHTPHVERVRERLLQLAAPITPRAGDVPMYSTVT
AAPIAGEALDAEYWYRNLREQVRFQDTLQTLLADGHTLFLESSAHPVLTTAVEETGHAAD
QHILATGTLRRDHGGVRRLLDALATLWTHGVAPDWTAVFTPGGAAPVDLPTYAFQRERYW
LAPVGPASAVRVDLPSVVTTEALDGFARRVADTAEGAPRLRVALDEVRRHAAAVLGLSSV
DEVETRKVFRDLGFDSLTAVELRNRLAVATGAALAPSAVFDYPTPLALAGHLLDRITGGD
TAGVGPYATGDVVADVAAALDEPIAIVATSCRFPAGVRSPEELWRLLLSEQDTLSAFPAD
RGWDLDTLYHPDPERPGSSYVHQGGFLQDAADFDAAFFGISPREALAMDPQQRLLLETSW
EALEHAGIDPLSLHGSRTGVFIGLVPHGYGGEGADTTGAEGYLFTGAAGSVASGRVAYSL
GLTGPAVTVDTACSSSLVALHLAVQALRNGECGMALVGGVSVMSTPGVFTEFSHQRGLAP
DGHCKPFAAAADGTAWAEGVGVLLVERLSAARRNGHQVLAVIRGSAINQDGASNGLTAPN
GPSQQAVIRQALANARLTPSDVDVIEAHGTGTALGDPIEAQALLATYGQDRSTEHPALLG
SMKAHIGHTGAAAGVASVIKMVLALRHGVVPRTLHVDEPTPHVDWASGAVRLVTENAPWP
EAERARRAGVSSFGVSGTNVHVILEAAPPAETVSEATPTEGVLPWVISGRTEAALRAQAA
QLRTYAATADRHLADIGWTLARHRAALEHRAVVIATDRDTFLTGLDAIATSEPATHVISG
TAPGEPPSGAVFVFPGQGSQWVGMAAELLASSPVFAESIDQCAQALAPHIKWNLLDVLRA
TGDDTALERVDVVQPALWAVMVSLARVWRAFGIEPAAVIGHSQGEIAAACVAGALSLEDG
ARLIALRSRLIAGELAGHGGMVSLATSADQTHELLTGRDDIWIATVNGPTTTVIAGDPAA
LTDVMAQAEATGIRARTIAVDYASHTPHVERIREQLRQLAAPISPRAGDVPMYSTVTAAP
IDGEALDAEYWYRNLRERVRFHDTIRTLVTDGHTLFLEASPHPVLTTAIEETGAHATGTL
RRENGGIRQLLTSLATLWTHGLTPDWSALLTPNTPTPADLPTYPFQRHRYWLNTAAPGRH
RATAGPDAHTGFWEVVEREDVEGLARTLRLEESQAELTTLLPALSAWHRRQSAAATMDAW
RYREGWRPLPETTAPALSGTWLVVLAPDQKGGAPHEAVATALVRHGATVETVVVAPDDPR
HWADTLTAHATAPAAGVLSLLVRDEAAGLHHTVRLIQGLEAAGVSAPLWCVTQGAVSVGD
HDPLTGPAQALVWGLGRVAAQELATRWGGLVDLPQELDERTTTRLCAVLAADGHEDEGTV
HEDQVTGHEGQVAAHEDQVAVRAAGILGRRIVRAPRLAEVPDDGWTPGPGTVLITGGTGA
LGSQVARRLAARGAEHVLLVSRRGDTAPGAAELVAELTASGAKATVAACDVGDADALRAL
LGSIPSAYPLTSVFHTAAILDDAAIGSLAPEQVDRVLRVKADAAWRLHELTQGLELSAFV
LFSSLAGTVGMVGQGNYAPANAYMDALARHRRARGLVATSVAWGSWAQGGMAERDAVTEL
RLRHGVPLLPPESAILALEAALTDDETALVIADIDWDRFAHAYTAARPSPLLDKIPEARR
ALGTVDGAEAGAPGSGMSGTGGTGGTGGAGGTVANLRDRLADAKPEERERRLLDAVRGQV
AAVLGHDSADDVGTRRQFLELGLDSVTAVELRNRLGNITGLPLPATLIFDFPTVTELVGY
LSTQLFTGIGDGPDGSGPDGSGPDGSGPHGDAPVATGDGTAELDRLERLLSTLPSDAPAR
SAIADRLRRLLRSAVDSTDAMDTADEPATSEDLEAATNDELFDYIEKEFGIS
>A0A5B7V3B9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MVNDDKIRRLLKQVTADLHTTRRRVRELESKDAEPVAIIAMSCRFPGGASTPEALWELVR
DGVDTVSAFPGNRGWDVAGLYHPDPDHQGTTYTREGAFVYDADAFDAGFFGISPREARAM
DPQQRLLLETAWEAVERAGIDPQSLRGSRTGVFTGTNGQDYTAVVAEAADSVEGYSGTGN
TAAVVSGRLSYTLGLEGPAVTVDTACSSSLVALHLAAQALRQGECGLALAGGVSLMSTPT
AFVEFSRQRGMAEDGRCKAFAEAADGTGWGEGVGLLLLERLSDARRNGHEVLAVLRGSAV
NQDGASNGLTAPNGPAQQRVIRAALANARLTAADVDAVEAHGTGTTLGDPIEAQALLATY
GQGRPRTRPLWLGSVKSNIGHTQAAAGAAGVIKMVMALRDGVLPQTLHVDRPSSHVDWSA
GAVELLTERRAWPEQEDAPRRAGVSSFGVSGTNAHVIIEEAPAAEPQGRPDEGPAPAAGA
DTDAATAPTDGAPDVRPAVGPTVWPLSGRTAKALRAQAARLRERLLDDPALAADADARAD
LGWSLATGRSAFEHRAVLIGEDRDRLLTALESLAAEGPAAPGTVTGSVAEGRLGVVFTGQ
GSQRTGMGRELYEAFPVFAAALDEACSHLDPWLERPLQSVMFGTDADLLEQTGYTQPALF
AVEVALFRLAESFGVRPEVVGGHSIGELAAAHVAGLWSLEDAARLVAARGRLMQALPRGG
AMLAVQAAEADVAPLLEEVAEWAGLAAVNGPAQVVLSGDRGILEDLAAQLRADGRKTRWL
KVSHAFHSPLMTPMLDEFRQVARGLTYQDPTLPVVSNVTGALAAADELKDPEYWVRHVRE
AVRFHDGLGALTGFGATTLLELGPDAILTAMAHDTLTGPEAQAGLVPALRRDRPEPDTFL
TALARLHVRGTTVDWTPRYAPLGARRRVALPTYAFQHQSYWLDTAAPAAPGQTAGTAPAD
SAEARFWEAVEHEDLGELTGALDVPDDAPLSDVLPALTAWRRKQRTSSALDSWRYRVTWN
PLPPQASTYGPALTGTWALLVPDALADQPWSAAAERALAAGGTRVVVVRVPEGASTDRAA
ATALLRQQEADQWNGVLSLLALTGPERPGTTGETPLAALRTAVLLQALGDAGSTATVWAA
TRGAVSTTPAEAPADPAQAAVWGLGRVAALEYPQTWGGLVDLPEAADAGAVTGLTQALGA
LEGEDQVAVRGSGVLVRRLVRASLGEAAGTAWTPRGTALITGGTGALGAHVARWLAREGA
EHLVLTSRRGPDAPGAAELKAELEGLGTAVTVAACDAADRDALARLLAQIPEGTPLTGVF
HTAGVLDDGVLDGLTEDRVAGVFRAKVESARHLDELTSHLDLSAFVLFASFAGVVGGSGQ
GTYAAANAALDALAETRRAAGRAATSVAWGPWGGTGMAAEGAAAERLKHGVMPPMDPDLA
IAALHQALSHDQTLTSVVDIDWAQYAPGFTATRPSRLFADVPEARAALTPPAEPTGAPGT
ATGAAPANALADQLAALAPEDREAAVLDLVRRRAADVLGYPSVDDIQVNRAFRELGFDSL
TAVELRNLIGAATGLKLPTTLVFDYPTPAALAAHLRTELLGDETATALPAPVTGGTATDE
PLAIVGMSCRFPGGVRSPEDLWRLVADGVDAIAEFPADRGWDTGALYDADADQAGTSYVR
QGGFLYDAGQFDAKFFGVNPREALAMDPQQRLLLETAWEAFERAGIDPAGLGGSQIGVFA
GTNGQDYTAGVDHVPDEVEGYLGIGNAASVASGRISYTFGLEGPAVTVDTACSSSLVALH
LAAQALRQGECTMALAGGVSVMSTPGTFIEFSRQRGLATDGRCKAFAEAADGTGWGEGVG
LLLVERLSDARRNGHKVLAVVRGSAVNQDGASNGLTAPNGPSQRRVIRAALANAGLKPGD
VDAVEAHGTGTTLGDPIEAQALLATYGQERATAEPLWLGSIKSNIGHTQAAAGVAGVMKM
VMAMRHGVLPKTLHVDAPTTEVDWSAGAVELLTGARDWPEHGDGTPRRAGVSAFGVSGTN
AHVIVEQAPAGEPEPTADGGVAPTSVLPLALSAKSPQALREQAERLLTRLRADFGAAPAD
VGLSLATTRSRFEHRGVVLGRDREELLAGLQELAAGTTTATRAVSGRAPDGPVRPVFVFP
GAVPGEAAEWTDTVRELLAESPVFADRMRACADALAEFVDGNLLDELDADRLDGADAAGP
VLFAVLVSLAAVWRAAGVEPAAVVGHGAGEIAAACVAGALTLRDAARVAALRERPDEDAG
TTLTDLAPRPADVPLYSTTTGEWLTDSTPMDAGYWRRNQRQEPLFEQAVTGLLAAGHGLF
AEVGPHPVLGDALRRTAGADGRTAVVLGAPHGTRGGTRRLAAAIAEAHVHGVELDWAALF
PGARADVDLPTYAFQHEHFWLVDGRAPGGAAQPATDDTDARFWEAVEREDLQQLAAELEV
ADGSAAELGAVLPVLSSWRRQRRERSTVDAWRYRVTWKPLTGGLPAPALTGRWLVVVPEG
AAAHPWTQGVTDALTRAGAEAVELRVAEHEVTPDALAERLRAHTRDGDAPAGVVSLLALD
ETPLADHPAVPAGLAGTVALVRALQDTGIEARLWAVSHGAVSTGRSDRLTSTAQAQLWGL
GRVVALEHPDRWGGLVDLPQDPDARAGARLAAVLAGIPATDGDSGTEDQLAVRGSGVFAR
RLAHAPLDTRPAQQWTPRGTALITGGTGALGAHVARWLAGEGAEHLVLTSRRGLDAPGAA
ELKAELEDLGTAVTVAACDVAEREAVAALLDGLAADGHTVRSVFHAAGVSPALALADTTP
ADLHEALAAKAAGAAHLDALLADAELDAFVLFSSIAAVWGSGGQAGYGAANTFLDAVAER
RRARGLSATSLAWGAWGGTGMAATAEAEEHLRRRGVGLLVPDLAVGALAQALALDETCLT
VADVDWERFAPAFTAGRASPFLGALPELRPRPTGRATAATAGDAAPLSAWAAELAGHPEA
ERQRLVLDLVRTEAAAALGYAGAEAVEPTRAFRELGFDSLTAVELRNRLTAATEVQLPAT
AVFDHPSPDVLARHLLGELTGATAATAAPAPVAQPADVADDPIAIVSMSCRFPGGAHTPE
ALWQLLVDGTDAISVFPADRGWDLEGAARYKPEGGFVYDASEFDAGLFGISPREALAMDP
QQRLLLETGWELFERIGIAPKSLRSSSTGVFIGSGFQGYATGLDSVPEGVEGHLMTGTSG
SVISGRLAYSFGLEGPAVTVDTACSSSLVALHLAAQALRQGECDLALAGGVTVMATAGAF
DEFSRQGGLAGDGRCKPYAEAADGTGWGEGAGLLLLERLSDARRNGHEVLAVVRGSAVNQ
DGASNGLTAPNGPSQQRVITQALANARLAPEQIDAVEGHGTGTALGDPIEAQALIATYGQ
DRPADQPLLLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGVLPRTLHVDRPSTHVDWSAGA
VELLTQARDWPDRGGPRRAGVSSFGVSGTNAHVVVEQAPRRGKAATEPSRPAAAAGTGPV
PWQLSARSADALRAQAGRLRERLVADPALAADPAALADVGWSLATGRSLLEHRAVVLGRE
RADFLTGLDALASGTPSDAVAGTVAEGRLAVLFTGQGSQRIGMGRELYEAFPVFADALDE
ACAHTDRWMERSLQSVMFGTDADLLEQTAYAQPALFAVEVALYRLAESFGVRPEVVGGHS
VGELVAAHVAGVWSLEDAARLVAARGRLMQALPDDGAMLAVQAAEADVLPLLADVADRVG
VAAVNGPAQLVLSGDRAALEGLAETLRGQGRKVRALKVSHAFHSPLMDPVLEDFRKVAEG
LTYADPVLPVVSNLTGELAQAAELKDPEYWVRHIREAVRFHDGLNALTGQGVSTFLELGP
DAVLTAMAHDTLTDPAAQAGLIAAVRKDRPEPDTFLTALARLHVRGADVDWTPLYAPADE
RRRVELPTYAFQHQHYWLETAAAAAAADGPVAADEVESRFWETVESEDLAELAKTLAVPD
DAPLTDVLPALTAWRRQRRESSALDRWSYRESWTPLTETAAGDLTGSWLLVVPEGRTDAP
WSTAVAALTAERGVRLVTVEVPGHATDRHTVAELLRAAAGDTAPDFDGVLSLLAADAPTD
GVVDGDAALTLALIQALGDTGVDAPLWCATRDAVAVGAADGRTAPERAALWGLGRVAALE
YPERWGGLVDLPEAADTAALARLARVLGGAHAGEDQVAVRGSGAFGRRVVRAALDDAHAT
GWTPRGTVLVTGGTGALGGHVARWLAREGAEHLVLTSRRGAEAPGAGELRAELEESGVRV
TLAACDAADRDALARVLDAIPADAPLTAVFHAAGVLDDGVLDGMTAERFATVFRAKATSA
RNLDELTAGLDLSAFVLFSSFAGVAGGPGQGSYAAANAFLDGLAHARRARGLTATSVAWG
PWAGSGMAAEGVAAERLRGGMIPPLDPDQAIAALHRLLAHDRTAALVADIDWPQYAPAFT
TVRPSRLYAELPDVRRLADAAPRGGAGQAAAAGTPDLAARLAALGRPEQERLLLDLVCEQ
VAAVLGYSGAAAVEPTRAFRELGFDSLTAVELRNRVNALTGLVLPATVVFDHPTPTALAD
CLRTELAPDAADPATLLLGDLDRLEGSLAAVGSADEITRTKVAVRLQAALDRWKNGAAVG
GGASGAAAESGTGGDVSEQLASASDDEMLEFIKKQLGRG
>G0PRM2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MTEDAKLLDYLKRATSELRQTRRQLSEAEARGREPLAIVAMSCRFPGGVESPEDLWDLVA
AGGDAISDFPDDRGWDLDALYDPDPGHSGTSYVREGGFLPDAGDFDAELFGISPREALSM
DPQQRLLLDTSWQLFERAGLDPLGLAGSRVGVFVGTNGQDYAHRSGTDQQEDEGYSLTGN
AASVASGRVAYVFGLEGPAVTVDTACSSSLVAMHLAAQALRSGECSMALAGGVSVMSTPR
TFVQFSRQRGLSADGRCKAFAAAADGTGWGEGVGLLLLERLSDAVANGHRVLGVLRGSAV
NQDGASNGLTAPNGPSQQRVIRQALSNAGLGAGEVDVVEAHGTGTKLGDPIEAHALLATY
GQDRAEGRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGLLPETLHVDEPSPHIDWSA
GEVRLLTEPVAWLGEERLRRAGVSSFGVSGTNAHVILEEPSAVETPAVGEPEAVVPVVSG
PVPWLVSGRGDAGLRGQAARLAGFVRGRGQGVDDVDVAGVAAALVGRAVLENRAVVVGGN
AVDLAARLDVLAGGGSVDGVVCGSPVGGKSAVLFTGQGSQFAGMGAGLYGRFGVFAGVVD
EVCAVADGLLPEPLRPVLFGEGGRGGLIDRTVFAQVGLVALEVGLWRVLVECGVRADVLV
GHSVGEVSAAVASGVLSLADAVRLVCVRGRLMEEVPAGGVMVSVAAPEEVVRGRVAGIGA
VWVAAVNAPGSVVLAGEEGDVRGVVDGLVAEGVRTRWLPVSHAFHTPLMDPVLEEFSREI
AGLSFEAPRIPVVSTVTGEVAGAGFGSAAYWVEHARRPVRFADAVGVARGLGVRVWAEVG
PQPALSAALDVREGEVVANFLRRDRDQATTLLTGLSRLHVHGVDVAWDSWVPRGTDSVDL
PTYAFQRRRYWLEGSARSVVGSGVDASTAEFWEAVERNDLGALGLDGDTPSDRVLPVLTE
WRRGRREHHALAGLRYHVTWKPVPQPADTTPSLTGTWLVVSHDEDVSAPLLALVDGLGAR
AELLIVEPGTGRAALADRLRAVAENAEPLAGVVSALALPGGAAPGEWHATADNLALVQAL
GDTGATAPLWCLTRGAVGTGTDDPVRDPEAAAVWGLGRVAALEHPDRWGGLIDLPADPDA
SAYQRLGHVLTGATGEDQIAVRATRMLACRLRRATAPALRDEPEWSPGGSTLITGGTGAL
GGHVARRLAERGAEHIVLLSRLGPDAPGADDLRRDLEALGSRVTVRACDISRRADVAEAI
AAVPAAHPLTTVVHAAAVLDDAPLSALTPERLASVLDAKATSARYLDELTRDLPLASFVL
FSAFGGVLGSAGQGNYAAANAVLDALADQRRAAGLPATAIAWGAWAGDGMAARSAATVLR
LRRTGARPMAPERALAALGRALGDGETHVLVADVDWSRFTPAYTAARPSMLLADLPDARG
ASVPNGAPAADGTGPALPEAARRLAALSGSERHAAVLDLVRGQVAAVLGHGDPNAIGSER
PFRELGFDSLTGLDLRNRLTAATGLTLPATLVFDHPTVGLLTARVDAELGTEAEPGAADG
TPQTRADGPGPVAPGPDGDEPIAIVAVACRLPGGVRSPEDLWTLLADGVDAMSDFPTDRG
WDLSRLHAPTDGPGTSYVRQGGFLSDAAEFDAGFFGISPREALAMDPQQRQLLETSWEVL
ERAGIDPRSLRGTRTGVFAGTNGQDYESLLTDVPDGEDFAATGNAASVLSGRVAYALGLE
GPAVTVDTACSASLVSIHLASQALRRQECSLALAGGVTVMSTPRAFVSFSRQRGLAPDGR
CKPFSARADGTAWGEGVAVLLLERLSDARRNGHPVLAVVRGSAVNQDGASNGLTAPNGPS
QQRVIRAALADGALTPADVDAVEAHGTGTVLGDPIEAQALIAAYGDRPVNRPLRIGSIKS
NIGHTQAAAGAAGVIKMVLALRHGTLPRTLHAEEATPHVDWSAGEVALLSEAVPWDRDDR
PRRAGVSSFGVSGTNAHIVIEEAPELPALELPAVEPSAPELPALELLAVEPSAPELPVSE
PPRPEGTSPTESLPVLLSARDDATLTAQASRLHDHLAAHPDLTLPDVAHALATSRAALEH
RAVILAPDRDELLGTLAALTDGRPAPAALRGVAGEGRVAVIFPGQGSQSAGMGRALYRSH
PAFAACLDEVCAAFAPELERPLLDVLHAEPGTPEAALLDRTEYTQPALFALEAALYRLVE
GWGLRPDHLLGHSVGELTAAYVAGVLTLPDAARLVAARGRLMQALPEGGAMLAVALAPDD
LTPLLDGHGHRVDIAAVNGPAATVLSGDEDAVLDIAARCAERGVKHRRLNVSHAFHSHRM
DGMLADFGDLASELDLAPARISIVSNVTGTALTPDEATAPEYWVRHVRETVRFHDGIRWL
YSRGVTVFLELGPDGVLSAMGAGCLPDAMDEVTFVPSLRPSWPEPRALTAAVGELHTRGV
PLDWRAIASEWGGRTVPLPTYPFRRRRYWPEPTAAPVPAADPSDTRFWDAVARQDITSLT
DELGVAETAALPELLPALSAWRERRDTESAVRDWRYRITWRRLTEPLRPRPTGTWIVVAP
SAPEVAADTTGVLSALDRCGARTRLLTVGPDGASDADAHADAGTALRAALDAADAPPAGV
LSLLGLDGRAHPGRPEASAGLIGTVRLIQTLAEAEAAEKSKGEAETRLWCVTRGAVAVDR
AETVTDPAQAQIWGLGRVAALEHPRGWGGLADLPAEPDDTAYDRLCALVTGGTGGAGGAG
GGGDTRGRATGSAGCRDIGEDQVAIRPAGVLGRRLVRARAAAPAPSADGGWQPRGTVLIT
GGTGGIGAHLARRLAAEGADHLVLVSRTGAEGPEASRLLAELGTRVTVVACDVTDRHAVT
GLVTRVAADGHPIRSVLHAAGVSHHASLADTTPDEIADTLAAKTTGADVLHEVFADTDLD
AFVLFSSIAGVWGSGGQAAYAAANAHLDALAENRRARGLPATSVAWGAWAGVGMASVGDA
AEHLRRRGITVMDPDRAVAVLRRAVADDEPQLTVADVDWDRFVPLFTGARPSRLLDELPE
ATQLSTAANADPAPVPDGLGRRVAALPETEGTRLLLDLVRAEAAAVLGHADADEVDAARA
FRSLGFDSLTSVQLRDRLATALGTRLPATLVFDHPSPDALAVHLRDTLLGLRPERSGGSL
PARGGQSGPAGSEGGDDPIVIVGMGCRFPGRVESPEDLWDLVAAGADAISGFPTDRGWDL
DALYDPDPEASGTSYAREGGFLAGAGEFDAGFFGISPREALAMDPQQRLLLEVSWEAMER
AHIAPDSLRTSATGVFMGTSGQDYLALSGDASSEGYLLTGNAASVVSGRLAYVFGLEGPA
VTVDTACSSSLVAMHLAAQALRSGECSLALAGGATVMSTPAGFVEFSRQRGLAPDGRCKP
FAEAADGTGWAEGAGVLLLERLSGARRNGRRVLGVLRGSAVNQDGASNGLTAPNGPSQQR
VIRQALSNAGLTGGEVDMVEGHGTGTTLGDPIEAQALLATYGQERPEGRPLWLGSVKSNI
GHTQAAAGVAGVIKMVMAMRHGELPATLHADEPSSHVDWSTGDVRLLTQAQPWSGQGGPR
RAGVSSFGVSGTNAHLILEEPPADELAAAEPEAVVPVVSGPVPWLVSGRGDAGLRGQAAR
LAGFVRGRGQGVDVAGVAAALVGRAVLENRAVVVGEGVADLVARLDVLAGGGLVDGVVCG
SPVGGKSAVLFTGQGSQFAGMGVELYGRFGVFAGVVDEVCAVADGLLPEPLRPVLFGEGG
RGGLIDRTVFAQVGLVALEVGLWRVLVECGVRADVLVGHSVGEVSAAVASGVLSLADAVR
LVCVRGRLMEEVPAGGVMVSVAAPEEVVRERVAGIAGVWVAAVNAPESVVLAGEEGAVRG
VVDGLVAEGVRTRWLPVGHAFHTPLMDPVLEEFSREIAGLAFEAPQIPVVSTVTGEVAGA
DFGSAAYWVEHARRPVRFADAVGVARGLGVRVWAEVGPQPALSAALDVREGEVVASFLRR
DRDQATTLLTGLSRLHVHGVDVAWDSWVPRATHSVDLPTYAFQRQRYWAAGSGGASAGSL
AGTGLVAAGHRLLGAQVSLAGGGVVFTGRLSVSAQPWLADHAVSGVVVLPGTAFVDLVVH
AGLQVGCGRVDELTLQAPLVLSGDGAGVTVQVVVGEPGEGGRRVVDVHSRPVDGGGGWTR
HGSGVLAGEVGAGGAAGGVGWSWPPAGDVVEGEGVYAGLVDAGFDYGPVFRGLRRVWVGG
EDVWAEVVLPDEPSGFALHPALLDGVLHALGVMSGGGEGGLPFAFTGVTVHRAGARVLHA
RLRRGAEGVRVEAVDPAGRPVVTVESLVLRPVSEAALRPAQDVPLRMRWDQVAVLSDEQP
FRHEDFALVSAGHHVGVADVVRSVDDGATAPAWVVLDLPVDATAPMPERARSLTAWVLGQ
VQTFLAAQVLAEARMVIRTRGAVFTGPGDRSPDPAVAAVWGLARAAVAENPDRLHLIDSD
SDSDFGVDSDSEFGFGVISESSVRGLLAAIRASGREQVALRKGMLLAPRLAPLEDDVLAM
PEGGSWRLAPGGQTLDGLRLVPDRTDPVDPADPDGLASGQVRVAVRAAGLNFRDVMVALG
MYPGRAALGAEGAGVVTAVGPDASGVAVGDRVFGLMPECFAPTAVADARRLAAVPDDWSF
TEAASVPIVFLTAWYALRDLADLRRGERVLVHAGAGGVGMAAIQLARHLGAEVFATAHPG
KWDTLRALGVAEDHMASSRDLGFRDRFTASTEGSGVDVVLNSLAGEFVDASLELLPRGGR
FIEMGKTDVRTEDQVPADVTYRTFDLADPEPDRIGAMLAEVVRLLRQGELDLLPITSWDI
REAPSAFRHLAQAKHTGKLVLNVPAPLDPDGTVLVTGGTGTLGSLLARHLVAEYGVRRLL
LIGRQGDDAPGAAELVEELRQSGAEARVVTCDVSRRDQVADLLDGIDPDHPLTGVLHAAG
VVDDAVIGSLGPERLAAVLAAKADSAWHLHELTRDADPAMFTLFSSAAGVLGAAGQGNYA
AANTFLDALAVHRHTRGLPAQSHAWGLWAQRSGISGHLTEGDLARISASGMVPLSTEAGL
SLWDRAVRRTDHPHLALLRLNPRHRHTHPLLADLSAPERTPRARAASAAGHTDDRDRLAG
LPGGERRRVLLGLVREHAAAVLGHLSVETVEDERAFKDLGFDSLTGIELRNRLNAATGVT
LRPTLVFDHPTPQLLAEYLDRQVTAGTPVADPDGDGDDGGTGGEDLTDDHLTEDEFRRIV
AAIPLRDLRKAGLTGPLLRLARDDGGPSAGPEERPEEIDAMDADDLIRIALDTFKD
>A0A1S7T3Z5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Agrobacterium fabacearum CFBP 5771|TrEMBL
MSVEIIGRSVRTPSARNADELFQLLKDERCVVTSVPEDRWSHARFWHPVAGTQGKAYTFA
AGVIEDVYDFDPAVFNLTTREATYMDPQQRVILQLVWRALEDASLTIPMLQGERVGVYIG
ASSLDSGNTFIEDPASGSPYFMTGNTLSIIANRISHVFGLNGPSLTIDTACSSSLVALDQ
AVRALRSGEIDTAIVGGVNVLAHPFSFVGFSQARMLSPEGLCRAYGEGGQGYVRSEGGGV
VVLRTTERTRSNRDRSYATILATGLNSAGRTNGISLPSREMQAALLRDVYERHGLDPNDL
AFIEGHGTGTKVGDPAELWAIGTELGLKRKQKLLVGSVKSNVGHSEPASGMFGLIKAILA
LEYNFLPASLHSAELNAEIDFQGLNVEINRSGSPMPRGQKPRLAGINSFGFGGTNAHIVL
ADPGKAEAADESALPSGPFMVSAQTRSALEGLLQNYVQELKSDRPDLRELVAVSAVNRTR
HRHRFVVDSEEPEVVCKGVEEFLAGSSTGFGRVGEAPAGETRIAFAFSGNGSQWIGMAQD
AYQYDRGFFDRFNEICAAFKPWLDVDLVSLFASQDLASSLPDTRIAQALLFAIQATLSDR
LISRNIKPSMVFGHSVGEIAAAYCAGALPLEHAVAVVAVRSRHQHALFGEGKMAAVALSA
DRAQEIARGNGLSGIEVGAINTRSSVTISGPVSEIKAFKEIGRKEHIPVHILDIDYPFHH
PVIDRERDAFLSDLPAYQPRSSGEIKFISSVTGTVESGDQLDAVYWWRNVRDVVRFADAT
AEALGQGCNLFIEIGPRPILSSYLSENARQAGTSVSIVPTLTRPALSSNPLPYIVAQAVS
CGASVWTDDVCSRRADVALPPLPFELRSLQVLPTSDKVNLLGRGDAEKAYTLLGWRTDPN
AASWKNHIDANLFPDLAQHVVDGKPILPGSAFIEIAVQAAQNFFMTPDVEVRNLEIIRPL
ELHENRLAELSTVISPETGQLEIRSREYLSEDDWSINAVGRIRKPVAEFARHTPQAAGNI
SDARTIDGSAAYRTARQFGLDYGVDFRLLENVRVSPDRKLLVRLFEARSPAHPYLSYNLN
PISIDAAFHGLVALFADLTGDLSGAPYIPVRFGAIRSRSGVADIRSAQIEILRASPFSLK
IRVELLDAQGELVASLDDCRFRRTFLKVHHNLETVSFHYEHIASAHDSSHDGLLPSLVPQ
YEATETAVSALMLDAAVYRASYDIAQKVQESFGSIDTTILNGRPSFRAYLANCFFTLEDY
GLATFAEERWQLASYPDLPAFADIIRELIAEFPENCPAAILVNDVYHFVMSSLDLLATDG
ESAELTDYEAPEATVDHFQNGTTIARKRIDEACRLVEAFLEKAASERPGLVIAEIGATSV
AVSARLANLVERYDAKLLIFEDDENLKSTLEVGFAKNPRVDVVDCSAGCLSRRIDLVVSA
NGFVLGRLKDSEALNSALIKIAKSGAELCFVEHQHALIADFVFGLREGWFSQSVLSELPV
GKMLPNEEMLERIGEVGFANGAFTRADFHDGSLTILTARGESTIDEHQQLRTRKSLLTIK
PKDTPFTYLSANKCVELECSSDLSVEALRDALAEVGTVELDVVLVLPEGSDAANHSSSLQ
EYICLLSDMAEILRHYSPGFEKHSPRLIIVAPGGSPANRTYANAINHAIWTFARVLQNEY
DEIEVVTIDVAGSVLTEKVWNQLLKLHEQGENELLYDAFDGSCQSLRAVSGPFKRAKQRV
RTFQAASIVQRSAGRIETIEWQENTLPVAGSGDVVVEVAATGLNFRDVMWAMGMLPEEAL
EDGFAGATIGMEFSGTVLSVGDDVHHIYPGDRVMGIGPNAFSTHVVVPEKGVTRIPDSID
LIEAATLPVTFLTAYYALVQLAGLRAGETVLIHGAAGGVGLAALQVAKLRGAKIIATAGT
VEKRNLLATLGADFVYDSRSLEFFNDVLRATNGLGVDVVINSLFQEAMERSLELVKPFGR
FLELGKRDYYADRKIGLRPFRKNVSYFGIDADQLLVAAPHITAKIFEEISTLLAEKALKP
LPYRAFSYDEVSTAFRLMQSAGHIGKIVVTPPERGKQTVVQARGSDFRVSPGTYLVIGGI
GGFGLEAANWLAEKGASHLALATRRGTLDEETREAIARWQEMGVKASVHSCDVTNEVQLS
SLLADLRKVAPLKGVVHAAMALDDALISNLSRERNQPVIHTKVEGAVILDKLTDADDLDL
FLLFSSATTMVGNPGQSNYVAANGYLEGLARTRRLRGKPALAVGFGAIADTGFLARNKQV
NELLSKRIGKTALKARDAMRFVEEFLIAMPADADGGTVMIADIDWATAATLKTVKQPLFS
AVSNSQVHGQISVGEQMDLHSVVAGKSIEDADAILHSLIAAELASILKMAENNITPDKVL
RDIGLDSLMAMELGASFQQKTGIDLPLSSISDSTTVGAIVGKLREKLVSRQSLGSNDDAD
DDLLEGLANRHSVQKLQEAVQ
>G3J039|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Methylobacter tundripaludum (strain ATCC BAA-1195 / DSM 17260 / SV96)|TrEMBL
MTTNSETGPAQRNLIKSALLKIDELQARLKACNAEKNEAIAIVGMGCRFPGGVDSPEAFW
QLLNDGRDAITEVPPERWDIDAYYDADPDAPGKMNTRFGGFIERVDQFDARFFAISPREA
VSMDPQQRLLLEVAWEALEYANIPPDSVYGSATGVFVGIIGQDYAQRLFAPGYLDKIDAY
VGTGASQGVAAGRLSYALGLTGPSFSVDTACSSSLVTLHLACESLRRKECDLALSGGVNL
ILEPGLNVNFSKARMMAPDGRCKSFDSAADGYVRGEGCGMLVLKRLSDALAAGDQVLAVV
RGSAVNQDGPSGGLTVPSGPSQEQVVRQALVNAGITPDAVSYVEAHGTGTALGDPIELGA
LDAVFSASHSAANPLYLGSVKTNVGHLEAAAGVAGIIKLVLALRHDSLPRHLHCDNPTAR
FAWADKPLRVLHEPQAWPRGERPRIAGISSFGFSGTN
>A0A139Y050|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii ARI|TrEMBL
MTDDVATGVRKTIFGANLAYGMGGSVAAIITESGDEEADRRSLKAAPRHVWNHRRFPLNT
QKFVYLMGAMGQISMDDMPTPQSDVIHVMKRLSATALNVAFMRKLSPSTCAAGSIRSVFL
TGATGFIGSQVLFHLLQVKRQDPKLGTEDKKLTIYCLVRARDRAHGIYRIRDSLVGRGIE
WKHEFDQQVIPVIGNLEEGENMGLGPKQMQYLEQTVDAVYHAADYVNFAAPYDALRKSNV
LSLIPILKLCTTYVAKPLHLVSNFAHHLQYFAGFSEDLNIAVDETVSPPLSPASIDRLEQ
QMPAGIIGYPWTKWAVEEIIGRMKDVLHERCEEEGQRVSMEESEKKDILSKFQVTVYRLP
NSCVYYNNGYTNFANASLSLVLASAQERMIPPGVLPVGAPFLTTPVDLITGILVKLSMTE
RKRHHVYHLVSLRVARRKHVVQAIKWLFPDSVECTADELFRRIDENKENSPAHPLRAAMR
FWRRYWYSSDTDRDSPFPVAVNNVEDDLPGVMATFPSLADTWLRMASYCVKNYHMVRHPF
TLAISFERLKKAIAGITKQRIDELALPSQTQELLNETCSTEDTTDIAAVKALVEHANLRK
YDDCAVSDVPDPRARA
>A0A139XW84|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii ARI|TrEMBL
MANAEKLVKLHGLWFRSLWKWAEKIPHEDAVIWLDENGSKAASLTYQKLRREALIIATCL
RQVHCQPGDRAILCYPPSVSFVPAFLGCQICGLTAVPVYPPGSNDRDSDSIQRIVAMVKT
TRPSVVLSSSPLRYFLKEVFPGAAARCVSDIRWIFTDELPDHVEAGSAFELDSLDIKSET
PAFIQFSSGSTGNPKGCVVTHMALLHNIHLNWRMCGAFHPGTEESLYDLPVESYAEFTEK
YQKHLVATWGHRLRSFSWLPVTHDMGLVGMLCVPLFFGCTAFFMSPIDFVRAPHSWLGGM
SKFGCSFTAAPDFAYALAARKVPDDLVLELNFEKILACVNGAEPIRPATIEAFLQKFAPA
GFQPWMMSPAYGLAEHTVGVTGRGSEGRKPMSPKIIEVNNEKVAQGDTVELFKRSGKQEN
EMRTKLIVGCGIPHEDVIVKIVDPRLLQELSEWQVGEVWVSSPSAASGYFGSPVETASTF
NLHLNTADGATRGDRSFLRTGDLGFLGDGELFITGRLKDVVILRGCNYYPQDIEEAVERC
DSVRKGGVMAFSISTTDDAEGLGVAAEIQKGSEKPAKLKLIYADIVRTVNKVLHLPLQRL
WLLRAGSLPKTTSGKPRRSEARRRLLQAERCDDILYSYTRNLSHSGHLPFRPGTFELDME
QKQEDSASTSKSEVNKSLVESLSTAKGARHTDDGFIFTNGQQNLHEAKKDQHGTSDSTLA
EPVSNAILDPITRVTDALLVTADGTSVHKDEEELSLVAECFACVTGVEKSCLRPDTPFLS
LGLDSLTAVELANEIQRRMKQPVEPFELFEFADLRSLALYLRNKKLDHGKDARGRQTKSS
PERSLGIVQVQRPSVFVTGVACALPGSCQTPDKLWEILDAGIDCVGPIPPNRNFCASQNF
AVIGEPRTANASFCVTEGGFLDDVDLFDNSSFGIPDAEAMTMDPQQRLLLMKAVEALHAA
GMATIDSRSAPIATFVGCCSTDWQRMNLGEQIQSFSATSHSASMLSNRLSYTLGLTGASI
TVDTACSSSLTALHCAMQELQHRHVPCHTAVVATVNLLLTTDVTLAFARAGFLSPTYRCK
TFDDAADGFVRSEGVVVFVLQTDVSETPTPSFKNQQEDNEGGQGECGTRIPASGYLCRIL
ASTVVHGGKTGSVTAPSGSSQELLYKQTFACAQVPPRAVDLVETHGTGTRLGDPIEISAL
CNSFAPDMETRKHRLVLGALKTNLGHLEGASGLAGLLKSVLCLNRQRVPPNLHLRKLNRF
IDFRSLPVLLPTKTVPLPASSSETKEAVALVTSLGFGGTYAQVAVQVPSTTGNEMLLRNQ
EPVQWNKKCFDVGKLVSQSNSFQSAVSHNDTKGPCFWEVGWEFLLEFDSITLTLPTLPEQ
APPAKWLVLTSPKAQQSFRKFSVNIFLPGIRMTFACLEELKAPEHLEAILKAETWTAIVS
TYTTETGSCMTDSSDLIGRTLQILQTYGQMASQSAVLPRILFLTQGCFQVGAAASLLRAS
PYNAGIIGFVRACRLEIESLSGRKAPIYLIDFAANGTLTETLSAVSKLLGMIDIRNVDET
EFAICGKRVFAPRLLPLHLGLEEILPAYDHYMDLTKKADESPAGTAKFPRLVEPANKACR
VRLLALCLDEIFPIEAISPASKAFELGESRPCTLPYGYRNRRQKAFLYQMERAFV
>F8AWN2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Candidatus Frankia datiscae|TrEMBL
MSTEHRQQIRPVPTGAPNGAADSAGLDTGVPHAVPAEAGSASRNAPADDFGGAPVDGIVN
GSPDDIAVVGLACRLPQAPDPAALWRLLREGRDAITDVPEGRWTIPADPAFDGMPRRGGF
LDRVDAFDAPFFGLSPAQAAAMDPQQRLTLELGWEALEDAGIVPGRLAGSRAGVFIGATW
NDYAALVDRGGPGALNRHSITGINRGVIANHLSYLLGLHGPSLVVDSAQSSALVAVHLAV
ESLRRGESDLALAGGVNLALTAEGTLAAWRFGALSPDGRSYTFDERANGYVRGEGGGVVV
LRPLCSALAAGNPIYCVIRGGAVVNDGATEGLTVPGLKGQTETLREAYRQAGVDPRTVDY
VELHGTGTAAGDPIEAAALAAVLGRGRPAGSPLLVGSAKTNVGHLEGAAGIVGLLKVALS
LHHGEIPPNLNFVRPNPRIPLDELNLRVQTALTEWPRAAGDRPALAGVSSFGMGGTNCHV
VVSAPPAVTGHPAETAPGRRPTARPAGSGSSPSVSSPSVSSPPTVISQPATSSQPAAAAE
TDTASEPAVVSRPVPAVVPWVVSARGTDALRTAAGRLADQLADQLAEDQPVDDQRGDDAG
PDSARPEQPGPAESADAPPEPAGTDLAGHPVSHPAGTVDPVDVAVALATTRTAFEERAVV
IGRTGGALRAGLRALADDQPAAGVIRGRSRRTADGGPAKLAVLFSGQGSQYPGMGRGLHA
AFPAFAAAFDEVVAHLDRHLDRPLRDLVFDGPAETLAVTAYTQPALFAIEVALYRLVESW
GIRPDLLAGHSVGELAAAHVAGVLSLPDAAALVVARGTLMRDLPPGGAMVAVEASEEEVA
PLLSGTVGFGALNGPRAVVVSGEQDAVTAIAEHFRAQGRRTSRLTVSHAFHSPLMEPMLP
AFRQVASELTFAAPTLPVISNVAGAPAGPGDLTTADYWVDHVRRPVRFGDGIRALAAEGV
TTFLELGPGTALTALTREVLRDITDRPVDGPADEPVLAAALRRGRGEPESLVTAVATVFT
AGTAVDWPAVAGRRGHPTRRVELPTYPFQRRRHWISTPTAGPTTVSTAGPTTGPATGPTV
EAPVAGIAAAAAAHGADAGSAADVTTGVGGTTATPAADRAARLAGLAGAERERRLLDLVR
TTVALVLGHVGTDEIDARHTFRELGFDSLGAVELRDRLAAATGLRLDSAVTFNHATPAAL
ARHLSDALAGDSATGAAGTAAPPTDGPGEPGPADEPIAIVGIGCRYPGAVATPEDLWDLV
AAGTDAISGFPTDRGWDLAALFGADPDQPGSSYVRAGGFLADADRFDAAFFGVGPREAAA
MDPQQRLVLETSWEAVERAGIDPVSLRGSRTGVFVGASPVDYGPRLHQPADGSAGYLLTG
GATSVISGRVAYTLGLEGPAVTVDTACSSSLVALHLAAGALRLGECSLALAGGVAVMSTP
GMFVEFSRQRGLAADGRCKAFAAAADGTGWSEGVGIVVLERLSDATRLGHPVLAVLRGSA
VNSDGASNGLTAPSGPAQERVIRAALAGAGLTPAQVDVVEAHGTGTTLGDPIEAGAILAT
YGQGRGERGPLLLGSLKSNIGHTQAAAGIGGVIKVIGALRRGELPRTLHVDAPSPHVDWS
SGDIRLLTEPVAWPAGAEPRRAAVSSFGISGTNAHVIIEEAPGAPEPVPAPVLDQAPAAA
AEPGQPAPDVAPDGISDGVTDRAMDTRGPAVPSLSLWPLSARDEAGLRAQARSLHAFATA
NPTTPVDDIAFSLATSRAGLPVRAAVPGADRVTLLAGLDALARDSADAGVIRGRVPDATG
PTAFLFAGQGSQRPGMGRELWERSPVFADALAEVLAALDRYLDRPLAELIFAAPDAPEAA
LLNRTAYTQPALFALEVALFRLAEGLGVRPDLLVGHSIGELAAAHVAGVLSLPDAATLVV
ARGRLMQSGQPGGAMIAIAATEREVRDSIAALRAELDAEHATRSDADGATRSDTNGAADS
DAGSDTGRDAGSGAGAVVDLAAVNGPNAVVVSGDADAVERVAAHWREQGRRTGRLRVSHA
FHSGHMDPVLAEFRAVAAALSFHPPRIPIVSTATGALATDEELTSPDYWVAQLRGTVRFH
DAIRDLDARGVRTYLELGPDATLTAAARQAISATAADAVAVPLLRPDRPADATVTAALGT
LWANGTAPDWRALFPGARRVDLPTYPFTRQRYWLTAPASTAGPDAAGHPLLDLRLDLADR
DEAVFSGRVSRASRPWLADHVIDGRVLLPGTVLLDLALAAGTRVGYPVVADLALEEPLAL
PADAAVRLQVAVGRPDSAGRRPVDIHARVDGPTPSTGTGGSAGADGATGTGPAPAGASAW
TRHASGVLTAVGADDSLSAPTPPAGADWPEPDGAVLDAAYRRLAEHGYEYGPAFTGLRRL
ARDGDTLRFEVALPEAATADSDGFGVHPALLDAALHPLVLELAPQQVGSDIALPFSWSGA
RLPAVAPDVLRVTATRIRPDAFALALLDQDGAPVGEIASVVLRPVSRQRLGRSGLDLATA
LHTLTWRPADLPGAGASLGAASSAGSADAADAAGSADTDTDTPRFVLLSDLASPNDLAEA
AEVTFPGEGDVVVPPAPPAEPGADLPAAARGTAARALRLVRDWLAADPDGTRRLLFVTRG
AVAARPGDVVTDLVNAAVWGLVRTAQTEHPGRFGLVDIDEPAVPAEPTVAAEPAVTTEAA
VTTEATAPADQPVTVTDGPARWWAAALAGLTPGGPEQVALRDGTAYVPRISRAEAVPGPA
EPAWDAAGTILITGGTSGLGALVARHLVAGGARRLLLVGRRGADTPGVDQLVADLAEHGA
TVTVAAADTADRAALAAALADVPAEHPLTAVIHAAGVLDDATVTSLTPEALDAALRPKID
GAWHLHELTRDIPLTAFVLFSSISGLLGTAGQANYAAANTFLDALAQALRADGRPATALA
WGLWDAAAGGMAVGLTDADVLRWRRRGVAPLPADLGVHLLDTAVAHGGGLLVPARLTPAT
IEGEPPTVLRDLVPAPVSAAAAAARPGAAGRAGGSWPELAAATDPDERERVVLDLVNATA
TAVLGHPPGTPLDPQRSFRDLGFDSLAGVELRNRLGTATGLRLPATAVFDHPSPAALARF
LLAQLAPAPVTAGQPAAPPARRATATAADADDPIAIVAAACRYPGGVRSPEDLWRLVATD
TDAISDFPTNRGWDVDALYDPDPDIPGRTYTRHGGFLHDADQFDRDLFGISPREALATDP
QQRLLLEVAWEAFERAGLDPTALRGSRTGVFAGVMYDDYASRLPATPENVEGYLLTGNTS
SVVSGRLAYVYGLEGPAVTVDTACSSSLVALHLAAAAIRAGECDLALAGGVTVMASPGTF
IEFSRQRGLSPDGRCRSYATGADGTGWSEGVGLLLVERLSDARRAGHPVLAVLRGSAVNS
DGASNGLTAPNGPAQERVIRAALASSGLTTADVDAVEGHGTGTRLGDPIEAQALLATYGQ
QRPAEQPCWLGSLKSNIGHSQAASGVGGVIKMIEAMRHGELPRTLHVDAPSEHADWSAGA
VRLLTEPVTWPDGPGRPRRAAVSSFGISGTNAHVILEQPTAADSAEAVITAAPAAGTDVD
TTDAADSTDSTDSTDTVDSAGTASGETAPVVWVVSGHDDAALRAQAGALRRFVAEQPAPD
IRDIAFSLATARARLGRAAVVAGRGTATLLAGLAAVERGEENLAARETGARGVRTAVLFT
GQGTQRPDAGAELHRAEPVFRAALDEIIAAFDPLLDRPLREILFAAPGSDAAALLDQTAY
TQPALFALEVALFRLVEHRGLRPDFVAGHSIGEIAAAHVAGALTLGDAATLVATRARLMQ
AAPAGGVMIAVEATEEEVTASLAEALAATRAGTSAGSSADATGTVDIAAVNGPTAVVISG
SAGIAQRVAAGWRDRGRRVRQLRVSHAFHSAHMDSVLDELRAVVGTLNVTAPRIPVISNV
TGRPAGVEQLASADYWAAQLRGTVRFLDGVRYLDGQGVSSFLEVVPDAVLTAMARDCLDG
ERAATAALVPSLRSGRPEAETLTVALARLYAHGSALDWARALPGARRTALPTYAFQHARY
WLDPAPTRPDADGLGLWNTEHPLLGGAVELPEDAGVVLTGTVSLAGTPWLADHALFGTPV
LPGAAVVELALHAARLVGAGALRELTLHSPLVLPDREAVRVQVTVGAPNDAGDRPVAIHS
SPPRTGRPQWTRHAAGVLAAADVPVPPAPGAGSGPLPWPPATAAEIPIGDGYDRLAEHGY
DYGPAFRGLRRLWRDGEAAYAEVTVNVATDVAAEADAGPDGGTSAPGFLPHPALLDTALH
PLAFEAALPAEGASAGTRVPFAWSDVRLHTSAFPRTVRVRIVPAGTGTVTLTLTDSADSP
LLTVAALTLATVDRARIAAAGGGRNGSLHTLAWQPLTWRPGTAPASAPVPPGWTVLDLRH
DPAETGPDGPLEVDAAARHTAHETLRAVQRWLADAESRPADARLIVVTQGAVSVSNGDEV
TDPAAAAAWGLVRTAATEHPDQFVLLDVDSAAGAAGTSGTAGTNGTGGTNGTGGTAGARD
AVSPVPADLPLDEPQLALRGTTAYVPRLAATAPGGETPRLDDGTVLVTGATGLLGGLIAR
RLVTVHGARHLLLVSRRGRDAAGADELAAELTELGATVTVTAGDVADRDALRELLTAIPA
EHPLIAVVHAAGVLDDAIVEALTPERLDAVLRPKVDAAWNLHELTRELDLRVFSLFSSVT
GILGTAGQANYAAANAVLDALATHRVARGLPGTSLAWGLWGGEAGLGADLSRADLARLTR
TGVVPLDLDEGLELFDATLGARNPVLVPARLDPTPLSAAGSVVPPPLRSLVAARRPRPAA
TTTGTDPDGDLAGQTPRDRLLALPPRERADAVAALVHRGVAAVLGYAAGETVEADRTFNE
LGFDSLTAVELRNKLAAATGLTLPTALIFDYPTPTALTGYLLRDHLSAADDTAATAATTT
TVVTPGTSAAPDDDPIVIVGAGCRFPGGVTTPTELWELINSGVSAITEFPTNRGWDLNHL
YHPDPDHPGTSYTRHGGFLHNAGDFDPDFFGISPREALAIDPQQRLLLETTWEALEHAGI
DPTTLTGTPTGVFAGIMYDDYGARLHLAPSAPASLEGYLVTGSAGSVASGRIAYTLGLQG
PALTIDTACSSSLVAVHLAVQALRRGEITLALAGGATVMASPATFIEFSRQRGLAPDGRC
KPFSADANGTAWGEGAGVIVLERLSDAQRNNHPILAVIRGSAINQDGASNGLTAPNGPAQ
QRVITAALADAGLTPADIHLVETHGTGTTLGDPIEAQALHNTYGQHRPADQPLFLSTIKA
TLGHAQAAAGIASIITTTHTLRNSHIPATVPTGTTPTPHLDWGTTPLTLATTPTPWPTTT
HPHRAAVSSFGISGTNAHLILEAPPGDASRVLDTPGTPSISITSSTSDISDAHATSADGV
TSTADTGTAVTASSAVTAEPRPVPPVPLLLSARTPTALNAQATRLHAHLTAHPDLDLRDV
GHSLRTTRSLFAHRAVVVAADRSEALAGLRTVAAGGGTRGAPRPAAGPGRTAFLFTGQGS
QRPGMGRELHDHHPVFAAAWDEAAAHLDPHLGRPLRDLVLAPPRPESTAILNRTALAQAA
LFVHEVALYQLVTSFGLTPDYLIGHSVGELVAAHLAGVLSLADAAALVVLRGRLMQSVPE
GGAMVSLHATEDEVAAELAELAELAGRVSVAAVNGPTSTVISGDEEVVADLAKRFRARGV
KARRLRVSHAFHSPHLDSVLDEFRRQAGRLTFTPPAIPVVSNVTGALATGDDLLSAGYWT
RHLRGTVRFQDGIRTLEDLGVTRFVELGPDGTLSALATASLRDPAAGIQVPLLRDRWPEP
RALLTALGRLHADGAAVDWAPAIPADARRVRLPTYAFQHTRYWVTTRPLRPAEPVDDPGT
DNTTADHAAAGHGAVDGHAADGAAPPAAWTGQWWQELAAASEVEREHLLVELLRGHIADI
LGHASADLVDPEASLIDAGLSSFTSLELTSRLHAQTGVRLPPTAVFDHPTAAGLARLLHA
ELTADRAGERQPAVPTA
>D9T193|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora aurantiaca (strain ATCC 27029 / DSM 43813 / BCRC 12538 / CBS 129.76 / JCM 10878 / NBRC 16125 / NRRL B-16091 / INA 9442)|TrEMBL
MTQQTDPAHAVVLSAADPERLRRSAHRLREHVSTADPALDLADVAYTTQVGRMPLPHRLA
VRCASVADLVGGLDAYLRGEARDGVLHGVAGAPFAPAAAPTDADAAADWVGGGLVDWRRY
WPGPRPRVPLPGYPFGAAPPAPPAARPRDPAGSLRAYLVEVYAEVSGLPAESVDPLLPLT
ELGLSSFLVTRLTARLENDLGERSRTLFFEHATLGEVAAALAAAGRTAPAGAAPAEPAEP
AESAAPAARTESVAPAESAAPPAADVVPAPAVAVEREPEEERETEIAVIGVAGRYPRSPD
LDAFWDNLAGGRDCVTPHPPERARPGWPTHLMDGGYLDDVDRFDPLLFGITPRDAALMDP
QERLFLEVTWAALESAGYTRARLRERHHSSVAVYAGAMWNEYPLFGAERTLRGVPQDSGA
TLGGIANRVSYCFDLHGPSLTVDTMCSSALVALDLAVQSLRRGEAELAVAGAVSLSLHPN
KFIQQHRMKLTATDRRSRTFGAGGDGFVPAEGVGALILKPLRRALDDGDPVHAVIRGTAV
VHAGRTNGYIVPSPVAQADVVRRALRDARTGPAEIGYVEAHGAGTALGDPVEIDGLTRAY
RDAAGTDLPPGSIPIGSVKSTIGHTEAAAGLAGLTKVILQLRHGVLAPSLHADELNPNIP
WDAVPFRVQRQRAEWTGPRVAGVSSFGAGGTIAHAVVAAPPARTRPAAPPGPQLVVLSAY
DEDRLDEVVRRLVAYLRRDRGPSTADLVAAVRRIAAGEHPGSAADHAAALLAHDGPALAD
IAYTLQVGREPLRQRLAVVVEDVATLCERLTAYRTDPAVLRGRAPAAPDPDAVPPAGASL
TDLARHWVAGGAVDWAALHEPGRTVVDLPAYPFARMRCWAPEDTPAGVSSGTQAPTVAAA
PGAEVPLYVKGWEPDPDPGPAASPVAGVMLCVGGSPDLVARLGGLAVRDVADLAAVLSRV
PDVGGLVGLPGGPGWETRVRMVQRLLAERPTTPLRILETAVDDVRTAGFVKVLGAEYARV
TATVLHTDRTGDDADLATRILAEWVRADAYGEVRYADGRRYRPRLDLVPAPHAPLRCDPD
GAYLVTGGTRGVGALVARHLAGHGARSIALVGVHADTGVADDLRARGVRVLQHAGGFPGV
EEFLRQVRAELGPLRGVVHCAGVESRGNPAFLHKDLADVRAVMAPKLDGFETLAPLCADD
PLDFFLVFSSVCATVTGLAAGVSDYAAANIAVDELVRARIAAGRTEFRSVDWPQWAQTGS
TSGRPNPCAPAGLAPLDDAAGLRVVDRVLALPAGAVVLPCPPLGDAPDPDALLRLRPRRP
APTSPPVVAGAPAAGTPAPGSATASVPAPASVPAPASVPAPASVPASASASIPAPAQALT
TGTATAPAAPGGPAAPPGWLVGIFSAALGIPERDLDPTVEFGDLGVDSVLLGELLIRIEE
RLGTHLDPATLLLHPTLERLTAHLGVQAATPEPEPPTAPEAVNSPGPVAAPVPVTPPDAV
TAPVPVTAPVPVDEPVPTAAQAAVVAGGGARPDLDRRVAVIGMACRFPGATDVVTLWDNL
LHGRCAVTEVPAERWDHRRWYSPEPGLGRSISKWGGFVEGIEWFDPGYFDMSDDEARCLD
PAIRMFLEGTAECLAEAGYAPDELRGRRVAVVAGARLSDYGRRVPIRTDVLRSDQNFIAA
RVAHHFDLRGPNLVVDSACSSSLVAVQVACRSLLAGESELAVVGGVEVLLDPETYLDLSA
ARALSPTGRCWTFDERADGFVPGEGCGVVLLKPLAAALADGDRVHAVIDGVAVNNDGHTM
GVTTPSPAAQADVVRQALAAAGRRPADITMLEAHGTGTLIGDPIELRALNDVFGDRPGGR
IEIGSVKSNLGHLLSAAGMAGLFKVALALEHGTIPPTLFCDTPNPRFDFDRSPLHPTTEP
VGWPAGRERVAGVSSFGLGGTNAHLVLSGAPPGPVRRAPLPRPVFRRRRLWLDGDGPAGA
PPPARPDTGEPLTASLLRLQLVTTD
>A0A1W7LPR2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Clostridium beijerinckii|TrEMBL
MKDNNIKMSISCGKPITNKYCNKMNIGNLLIEAAENQKDKGILLVQGNNSDVFLTYEEIL
EKAMLCLGALQEKGIKKDDFAIISFQNNIDFITCFWACILGGIVAVPISTPSAFKGKNAS
LEKLINVWHTLEKPVIISDNSIIKGMKNNDFYSECQEMNMLDISILRESKIKGKMNLSET
EKPAFIQFSSGSTNTPKGVVLTHKNLLTNIEGIADSAGLTTEDRVLSWMPYYHDMGLIGF
HLTLIALGMFQINMNPMKFVKRPTLWFDLISEHKITITSSPNFGYRLLLRKVTDKHLKEW
DLSSLRLIFNGAEPISMPLVNEFMEKLSVCNLSKTSMFMVYGMAEACLAVTFPPLNSKPL
SHFISRNSLVNKSEVEEVDESAKDALQVADEGYPVAGMQVRVVNDDGEIVPENILGEIQI
KGENVTKGYINNPEATAKSFQDGWLKTGDTGFIIDGRLCVTGRIKDIIFVNGQNFFAHDI
EFKLEEIEGVETGKVVVGGWHDEKEGREKIAIFSSLRVKEDELKSFYGNMLSKINEAFGI
YIDFVVLVKAIPKTTSGKVRRFMLVQSFLDNEFVDSTLTSGELLLNIEEKAEEADESKAS
PLNISREKIKEIWADVLDRPAQSIGYNQSFLSLGGTSIKAVQVLGILEDELDITLGHDIL
INCRTINEMNEYLKNFSEGNSVLTNINEKVHGQVEEDDEIAVIEMSCRFPEASSPEEFWD
NIVNGKCSISEVPEDRWDVSKYYSKSGDKAKTYCKTGAFIDKPFDFDAKFFNISDEEAAV
MDPQQRIILELVFEILERAGYSKKKVSGESISLYIGAGTNTYQEYHLNTLNMSSLKNFDS
FNSLSKEVQESILEEWKNTLGVTEFHTNLLVDNILNMIAARTSQEFNFKGPSMVIDTACS
SSLVTIHLACEALRKGECELAIAGGINLLLTPTPYIYLSNAGALSTSGISRVFDAKADGL
VPGEGAGLVLLKPLKKALKDKDKVLAVIKASAINNDGHSIGVMAPNPDGQREVIESLYVK
SGISPKDIQYIEAHGTGTKIGDPSEVRALSNAFKRWNPESNSMAIGSVKANIGHLLNGAG
IASFIKVILAINNKTMPPNVNLNELNPSIKFDKTPFYTMLEAKKWEVQEGKMRKAAVNSF
GFGGTNCHMVLEEAPSEIIPAVEVQDYSRNKHALNLSANSPNSLQLKINNLVKYLKTNKE
INLGDVCYTENVLRTSFDKYRYSVVSETIEDLINKLQASKVEEINGDMQHKVALMFTGQG
SQYVGMGRELYNKLPIFKGYVDKCSEAFSPYLNEKITDLIYSDKADESILAQTNITQPVV
FTMDYAFGRLLIDLGIKPAYMLGHSVGEWAAACLAEVITLEDAAKIVSARGKLMGSIKSS
GCMCAVFTSSEKLENSLEKFKGAVWIAAYNGTHQVISGDEGDVDRFCSNLLKEGIGFKKL
KVSQAFHTPLMEPILNEFRKVFNGIKFNSPKIPLISNVTGKIMDEAFDIEYWINHILSSV
KFEQSIKYLSDKAVDVLIECGPDRVLSRMASGVQAQSARTILSLSDRKMMSFDVCLEVLS
SLFTLGFNVDFEKFESGIHYNKLQLPSYPFERKTYKPDFGNENIKVPDEWFYNWNWKAES
HKYAGSEIKGNIVIFSDGSGIEDELDEIFKLNKIYVVKAGSEYTFDEYSKFIIDPIVEKD
YAKVFNSIQGPIGAVIHLWNLNDEIQLEFAFDDKAMHEYIYSILYIGKALSKLNIEKTKL
LLVTNNGLSVNEENKISSPHQASAITLAQALDVENDFVDSYCIDVDKKEYVSKEEIAKIL
SDEIKHDLNKEGIVAVRGGVRFIRELVNNVELNQASKIKFNDGETYLITGGASAVGSEIA
KAIAKKAKINLILTGREELPDPEKWDNELVNNTKCAKKISLIMRLKVLGANVIYEAVDVT
KIDDMKVLIERISEKYGAINGVIHAAGTFDSKTFRLLDKDVKTINKVIEPKLKGSIITDL
VTRKEPLKFFAMLSSVSCSEKLWSAGVGDYAAANAFLSAYSYYRSADNGPGKTIALNYSL
WAGTGMGSDFGNGALLALKAQGVNPLPAKKASEAFMRALSVESKNVIHIIDKIEGSDVEK
SPTIKMPKVNSRKLKNIKEVVYKIIAKQLKVEEDNFDVGKNFLELGLDSLGAIKVMEVLG
TNIGMELYPTLIFEYQTPQALAEYIEKTYLEGFGEAAVSKIDDFNTEVVKEEKSKDIAII
SASLRIPGANNLNEYWRILENGECVIREIPEDRWPANDHYSEDTNSTYKSYSKCGGFIEN
PYEFDPLFFGMSPSEAAVTDPQQRIFLEIAWEVMQQAGYGGRYSTNNIGVFVGSEQNGYS
EHFTNYRIYMELKDKLLKSQTFNNMNSNEKYEIMSNILNVLKPAKMVPDAVAGNSLNEVA
ARVSHCLNLSGPSLTVNSACSSSLSALHLACESIRTGQCKMAIVGGVNLNTSPTPFIGLS
RVQALSKIGICYPFDDRADGMVLSEGASAILLKPLEDAIADNDNIMAVIKGSAMNNDGHS
QGITAPRPQGQADAVMRAYLDAKINPETISYVETHGTGTPLGDPIEIEGMTKAFRAFTQE
KGFCAIGSVKSSIGHMLSASGITSLIKVVLALENKKIPHTINYDKLTTNRNIDFENSPFF
VAAERTMEWEKSGVTPLRAGVNGFGFGGTNVHVILEEAPEKKRIEKVEEDFPYLLQLTGR
NQSVIKNIALELKEYINWHENLNIASICFTMNNSQKELSTKNSAVVESREHLLEILADLI
SDKDSECIYKGRSNPNRQTEAYLILDGRIKNVEKLKEDLSLRFDIFNIAYKECLTLASKS
ISNEKTSDFESFAVHYAIGVLLSNFEMKLYGIIAEGEGTGVLAASVLNGKINLRHALEQI
LGTIEAREDEILEDDKNVAYLNCPILTSSGVLEDALNISQNDDKNIRNLNGFVNKNQVII
YPGNLDEVKNKEFYNDKNFNWIGMDISRDSVKSIISTFAKLYTLGVRFNPSKLFKGNVKK
VMLPTYPFENETYKVSFEEELTYKESDHISMQRSGLRRMEMKHILSESEKRSISNQLSID
IGK
>D5PHG1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium parascrofulaceum ATCC BAA-614|TrEMBL
MSEDGFDRAGDPVAIVGMAVEAPGGIDTAEKYWELLVGGREALGPFPTDRGWQVRELLAG
SRRSGFKEIHDRGGFLSGATMFDPEFFGISPREAVAMDPQQRVVLRVSWRALENSGINPD
DLAGHDAGCFVGASATGYGPHMATFSPHSGHLLAGTALSVISGRVAYTLGLAGPALTVDS
SCASALAAFHVAVRSVQNGDCDLALAGGVNVLGSPGFFVEFSKQHALSDDGHCRPYSAQA
SGTVWAEGAAMFVLQRKSAALRAGRRVLAEVRATAVNQDGRSAGLSAPSGDAQVRLFRRA
MTQAGIRPEDVGMVEGHGTGTRLGDRTELRSLGQTYGDTAPGAGALLGSVKSNVGHALAA
SGALGLAKVMVAAEHGAIPPTLHAADPSPEIDWENQGLRLAKTLTPWPAAGGQRIAAASA
FGIAGTNAHVIVSLPEVA
>A0A1N6AD13|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus subsp. bolletii|TrEMBL
MTAVHVDPVVISGMAIEAPGGIDTPAAFWNALADGRELISAFPRDRGWPVDELLSLSNLD
GWGRISDAGGFITDASAFDPTFYGITQREAVAMDPQQRVAMRVAWRALENTGLNPGAVDG
SEAGCFIGISPNEYGPPVGEVNAHSGMRVVGRGQLGAAGRISHGLGLIGPSVCVDSACAS
SLAALHIAASAVRADECEWAIAGGVCVMGSPGGFYEFSRMHALDPDGHCRSYSDEANGTL
WGEAVGMVVLERESRARALGHRVYGRIMAVRTNHNGGGKPILVPRGRAQAKLVAATIAAS
GVDPADVGMLEGHGTGTRAGDPLEILALQSTYGAGGSNALLGSAKSNAGHAQSAAGMVGL
IKLLLSGQYGHIPPSLFADNPTTKIDWSMTGIRLATKLHPWEPKDGIRYGAVSSFGAGGA
NAHAIIAMPAMDTQGEDGDDF
>A0A8B4D8Z7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus subsp. massiliense|TrEMBL
MTAVHVDPVVISGMAIEAPGGIDTPAAFWNALADGRELISAFPRDRGWPVDELLSLSNLD
GWGRISDAGGFITDASAFDPTFYGITQREAVAMDPQQRVAMRVAWKALENTGLNPGAVDG
SEAGCFIGISPNEYGPPVGEVNAHSGMRVVGRGQLGAAGRISHGLGLIGPSVCVDSACAS
SLAALHIAASAVRADECEWAIAGGVCVMGSPGGFYEFSRMHALDPDGHCRSYSDEANGTL
WGEAVGMVVLERESRARALGHRVYGRIMAVRTNHNGGGKPILVPRGRAQAKLVAATIAAS
GVDPADVGMLEGHGTGTRAGDPLEILALQSTYGAGGSNALLGSAKSNAGHAQSAAGMVGL
IKLLLSGQYGHIPPSLFADNPTTKIDWSMTGIRLATKLHPWEPKDGIRYGAVSSFGAGGA
NAHAIIAMPAMDTQGEDGDDF
>A0A1U5V2M8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus subsp. massiliense|TrEMBL
MDSAENPIESTPRFAIIGYAARFPGAADAEEFWDVLREGRDAISEVPADRWDAEEFFDPE
PGAPGKVVTRRAGFVEDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGIAPTD
LAETNSGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQGPSVAV
DTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSHAHMLAPDGKCKTFDA
AADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
DALKRAGVAPSEVGYLEAHGTGTSLGDPIEAQAAGAAYGIGREANDPLLIGSAKTNIGHL
EAAAGIAGVIKVILSLENELLPQHRNFQNPSPHIPWDRLPVEVVREARPWGRNGRPRIAG
VSSFGFAGTNAHVILEEAPVVSQDAVDAPVAAGGRKFSILPLSARTPAALAQLADQYRTW
LNAHPEAALADLCFTAGVGRAHLEHRAALVVNTREAAVELLGAVADDRPAPGLGRGESHD
TPKTAWLFTGQGSQYPGMARELFETEPVFADTLNRCAAAVADVLEKPLLDVIFDVDGPEA
EEALRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAEVFSLEDGARL
IAERGRLFGSLPAGGRMAAVFTDAERAERLTDEFPSLSVAAYNGANTVLSGPAQDLEKAI
AALVADGVRCDFLETSHAFHSALLDPILDEFEAYANQFNYKTPQRILIDNRTGTALGRSV
QLDGAYWRRHARQPVEFAKSVRTLADMNCKVLLEIGPQPVLTAAALRAWPDPATAPRAIA
SLRRNTADHRQITEAAADAYVLGHLPDFGAFQHGPARKLDLPTYPFERRQYWFSDKRDGD
NRDAGNRQQNSGGPRTEAVRLLEDGKIEELANLLGGVDGDQQTLNVLTKLAAQHNLQRTT
QTIADDRYQFRWEKSPTPLSGSQAAGSVTWLLVGDAAGAAQPLLDVLTARGQQHRALALP
VSDADEAQLVEALRSAAAEDSALRIVHVAALDPGQGSSSTQSLLRIQHQVLGGTRRLFRA
AAAAELRAPIWIVTQGAQHVIEGDAVAPEQSALWGFGRAAALELPQVWGGLADLSDAGAD
EWAQFIGRVSVSGEASTREDQLALRGQAVHVPRLVRREELPSGKPLEVRSDATYLVTGGL
GSIGLEIAGYLAGRGAKHLVLTSRREPGEAAQQRIDALAAQGCEVRAVTADVADGHDVAR
LLAGVQAELPPLAGIVHAAGEIGTTPLSDLDDAEVDRVFAGKVWGAWYLSEAAAGLKLDF
FINTSSIAAVWGGYGQTAYSAANAFLDGLAWRLREQGIAGTSVNFGPWSAGMADAESRAR
LEQRGIKTLSPADALAGLADVVAASGSNAAQGVIARIDWARFLPLYQQAGKRGFLAELDR
EVPSHLAGAAAGGQSGSTQLVERLANAPVQQRKKLLTDYLRDAVAEVTRVDVSEIREDAG
FFDLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLGDVLGLNEQAKPAAQ
LASAVTHRTDEPIAIVAVSCRFPGAPDPEAFWDVLSGGVDAIREVPEDRFDIDEFYDPDP
EVAGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYSPAAL
RGSRTGIFAGVGANEYAHLLSSESIDKIEPYFITGNALNAISGRVAFALGFEGPAVAVDT
ACSSALVAVHQAVQALHSGDCDLALAGGVNVLLSPVTVIAASRARMLSPVGRCKTFDASA
DGYVRSEGCGILVLKRLSDAERDGDRVLAVIPGSAVNQDGASSGLTVPNGGAQQRLIGSV
LARAGLVGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGGSREADRPLLMGSVKSNIGHTES
ASGAAGLIKVVLSLQNGVLPQSLHFDNPSPHIPWESLPVRVVDKAIPWQANGRPRRAGVS
SFGFTGTNAHVLIEEAPQPQATPEEDDASTPRSAPVNVLPLSARSPEALAAVAQRYESWL
AAHPDVDLEDVCLTAGRGRSHFEHRAALVVDSIQAAREGLLELAQNRLRPGVVRGEHTNH
PTTAWLFTGQGSQYPGMARELFDAEPVFAETVTRCAEAVKDIVTRPLLEVMFATDRETGG
KAGEALRHTSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYTAACVAGVFSLEDGA
RLIAERGRLFGGLPAGGRMVAVFSDAKHVEQIAGEFPRVSVGAYNGPNTVLSGPGEDLEQ
AVARFQEEGIRCTWLETSHAFHSELLDPILDEFESYAAQVQFAAPTLPLVCNRTGAVLTA
QTPIDGQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAPPRA
IVSLRKGVEDRRQIADALASAYVSGHRPNFAALQRHPRRTVELPTYPFQRRRFWPKSSGT
AIEGGGGLPSGILGRGEDLASGDSVYISRLSVRSQPWLSDHVIYGTVVVPGATYAAMALA
AVGTPARAKDVFFYEPIILPEKSSREVQLTLHPLEDGSGSKFQVHSRPYGERDVDWSLNA
EGTVVTGIGDDAEPAPEAAEPAEPVDAAIERMERMRPMELFEIFADLELAWGPTWSGSLK
SLWLGEGEAIGDVLVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLP
LRYGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYLDRDGRHLGGIREFTVKRAPRE
ALLRGLGGDATRLLYTLGWHEVPVPPVADEGEESAASVGTWLIAGFDELAAKVPGCIPLN
RETDPELLGEVLVAAKERGVPFSGVVWRAAGPGATESTAESAARLEGEIAHLLSAVHTVQ
NSAQNGVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTINEEPALRAKLVDGDGS
PEAVQALARLLVTPVEEPEIAVRQGKLLASRLLPWSRTGHLTVPRGSDYVLAPTERGAID
NLRITEKEVPAPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGIVTQLGEGV
TGVEVGQRVYGSMQGAFGSRFNVPAQFLAPIPDGISGVEAATIPAAALTVRLSFDWAQLK
PGDKVLIHAASGGVGLAAIQMAQQFGAEVFATASTFKRATLRKLGVKYVYDSRTTDFADQ
ILADTDGAGVDVVLNSLTSEGFIEATLRATAKNGRFAEIAKRDIWSTEQMAQARPDIAYE
IVALDTVMFQEPDRIRVLLTEVSEGLAKGEWRPLPAEIYPLTEARTAFRRMQQARHIGKI
VCQMPNPLAPRPDRTYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRAPDTDAQRVIAEI
TERSKTRIHVFTADVGEESEVVGLLNRIRAELPPLAGVAHLAGVLDDALLGQQSVERFRT
TLAPKAFGAEYLDRLTKGDHLDFFIVSSSVSSLFGSPGQSNYATANALLDGLIAQRRAQG
LPATGINFGPWGQGGMASSEAATANISAQGLIPLDPSAALAALAEVVANGTGQATILKAN
WQRAAKVLGSSRPPILDLVLPSAVGEVTGDSELLKQLMEIPVPQRAGFVTEFLQREVQNF
LRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVG
QLPDADAESAEAPPAVESAEAESGTGPAAASDAVSELKE
>G6FT26|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Fischerella thermalis JSC-11|TrEMBL
MIVPNSSHDIAIVGMSALFPGAKDLRTYWQNILNQVNAVGDAPDKWAKPYFDPDSTANDR
IYTRKGGFLGDLAEFNPLEFGIMPSSVDGGEPDHFLALKLAWEALQDAGYIDRPFNREKT
GIILGRGTYINRGYNTLLQHGQIVDQTLDLLRQLHPDLDENTLNEIRKQLKASLPPFTAE
MAPGLVPNVITGRIANRLNLMGPNYIIDAACASSLIAVELAMKELLSDRCDMVLAGGVHA
STPPQINMIFCQLGALSRSDIKPFDSKASGTLLGEGLGIVVLKRLRDAEKDGDRIYAVLK
GVGSSSDGKALGLLAPRLEGEVLALQRAYQESGIDPTTVGMIEAHGTGIALGDQTEVRSL
TQIFGQRQEQLPKCALGSVKSMIGHCIPAAGAAGLIKTALALYHKILPPTLCDEVNPGLE
IEKTPFYINTQARPWIHGDRSTPRRAGVNSFGFGGINAHAVLEEYPTQPLQSSAWGLSPR
LLHQQWPTELLLFSGDSRSVLIERIHQVQQVLQNHPQAWGLSPRLLAEIAYTLSTHSVGS
HRLAVVAKDISELQKKLSQAVEKLHNSPKSRLQTRNGIYYAEVDTNVNPGKTAFIFPGEG
SQYPQMLADLCLYFPQVREWFDFLDATFSERRAYLPSQLIFPPPTSLTETERHHAQRRLF
DMDVASETVFTASMALYELLCNLGVNCDVMVGHSTGENAALIASGTVRLSDRMELMSKMR
LLNQIYLDLEVAKNIPKGALLTVGAIAPEVLQQVLDEFDGRLHVAMDNCPNQVVLFGSVN
DIDAATGKLQAVGGICTRLPFDRAYHTSLFAPVGNAFLAFYNDLDVGSGHTPLYSCATAA
PFPQEPQAIRALAAQQWSSRVRFRETVLQLYQSGVKNFIEVGPSSNLTAFVSDILYGREH
QAIASNSQRQSGLEQIQHLLARLFVNGNPVDTSALYLHRQITPISLDTTTQVGEIQKSSP
VLELTMPVLRLQPDFVNTVRGKLQASKDVSVSHATAIASTSPNPPVVKRPEPVAKDSSST
IPVVATVVSTNVNDTVAITTPVRNSVVKDSISDENIVTFSTSKTYANAGEDQSYTDEEQR
LSIIFDHFDLMQEFLDSQARVMTALHSHLASVDTGVIAPFVNMSLALPEANDWQPSTFDE
TFPLLGEILEHDAQHLYCQRRFDMQRDIFLYDHTIGGQVSQRHLDLFPLPVIPFTVSMET
LAEAAVYLVGQDKLVVGLYDLRGYRWLALDRGELTLKIKARLQSQPDAQTWEVKVQLFQV
GQGSTIDHLVFEGNVRLAKQFPVSPLPLPFHLETPAPSRWSDADLYRTGMFHGPRFQGVR
HIRQWGLQGIEADLEAIAIEDFFSNTQQPIFQIDAGLLDAAGQLVGYWVSEQFGTDFNVF
PFQVRAFHQYISPLPPNSAVLCRGLMRFTSEWQTEASFDFLDATGRVIARLEGWQDRYFS
VPHRYYQCRLHPQTAYLSDAWLQASWDLSPRLQMVVRRIEPFPEHFLDDSWSIWKRVLAH
LMLNESERLFWYNLPEKGTERTDWLIGCIAAKDAVRQWAKQNFNLELAPIDIEVISTTTG
KPVVRCPELEAMAGVLPEIAISHSQGFVVAAMAHPGKSIGIDLEHFDSVCVEGLVATAFS
ESELQQMPQRHQSSITGLWSAKKAVAQALGTGLQGNLTQLLITHVSSDGQWVTINYGNES
FVVQLCYSDREVLAICQHS
>A0A3G4VMB6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-16|TrEMBL
MAGTNEEKLLENLKWMTTELRRARRRIQEVEQDAQEPIAIVAMSCRFPDGVRSPEDLWRL
VSEDGDAITGFPDDRGWDIASLADPDPDRKGTFYNTGGGFLSDATVFDPGFFGISPREAL
AMDPQQRQILETSWEVFERAGIDPASVRGSRTGVYIGAGAMGYGADLKEVPEGLEGLLLT
GGATSVLSGRVSYVLGLEGPAATIDTACSSSLVALHLAIQALRQRECSLALVGGVCVMPT
PDVFVEFSRQRGLAADGRCKSFAAAADGTGWSEGVGVLLVERLSEARRNGHPVLAVVRGS
AVNQDGASNGLTAPNGPSQQRVIRQALENARLSAAEVDAVEAHGTGTRLGDPIEAQALLA
TYGQDRPEGRPLRLGSLKSNIGHTQAAAGVAGIIKTVMAIRHGVLPRTLHVDEPTPDVDW
SGGAVSLLTEPMAWPETGAPRRAAVSAFGVSGTNAHTIIEQAPPEAGPEGEGTDGAAAPE
AAPAAAGPAVLPWTLSGRTAAALRAQAARLIAARAQDGAAAPALDLGYSLATTRGALEHR
AVLIGRTDEDLDTALAALAAGEEAAGLVTDSVTEGRTAFLFTGQGSQRPGMGRELYENCP
VFAEALDAICAQLELPLKDVLFGSDAAALNRTEYAQPALFAVEVALFRLLESWGLRPDFV
SGHSIGEIAAAHVAGVLSLADACTLVAARGRLMQALPSGGVMIAVEASEEEVLPLLTDRV
GIAAVNGPRSVVVAGDEDAALAVAEAFADRKTKRLTVSHAFHSPHMDGMLDAFREVAERL
TYASPRIPVVSNLTGALVSDEMGSAEFWVRHVREAVRFLDGIRALEAAGVTTYVELGPEA
VLSALAQDCVTGETAAFVPALRGGRPEPETALAALARAHARGATVDWTAYFSGTGARRVD
LPTYAFQHSRYWLEPAATTAGDVSVAGLDPAAHPLLGAAVTLAGSDRVLCTGRLALRTQP
WLADHTVAGTPVLAGAAFVELAVRAGDQAGCGHVEELVLDAPLTLPADGGVRVQVLVEDP
DEQGRRGFTVSARPEGDAAEDTGWTRHAHGVLAPAESPAAAAGLAQWPPAGAQALDISGL
YATDGATDGAGTGPARGPLFRAVEAAWHHDGAYYAQLRLPEDAPQAADFGLHPALLDAAA
HTALALAAPYADGAGSGVGPGSVWSDVTLHATGAGALRVRIRPAADGAFALDLADDLGDP
VATVGRLTPRPFTAGTTGAPAAVPAVVREALFQLDWTPLPLPSRPEGVAAPAEPAGGWAV
LGSTGSGPATRHADLAELAAAIDAGAPVPAYVLAPFPRQADGLAPDTLREAAHRALALVR
GWLADTRFETSRLVVVTSGAVAGPGEGGTDLPHAAVRGLLRSAETENPGRFLLADVRDLA
DLDDPAGAALLAEALASGEPELLLRDGAVHVPRLRRTRPAATPTAGTTDSDPAAGAGAAG
PAVVDPNGTALITGGSGTLAGIVARHLVTAHGVRRLLLLSRRGADAPGAAERTAELAALG
AEVTWAACDAADRDALAAVLEAVPAEHPLTTVVHTAGVLDDGVVGSLTPERLDTVLRPKA
VAALHLHELTRELPVTAFVLYSAIAGTLGSAGQANYACANVFLDALAQHRHHQGLPATAL
AWGLWADASGMTAGLDEAQLRRMEQHGVGALTAGDGTALLDAALASGRPVLVPARLNPAA
LAAAAAPGPVAPVFRELLGPAGRRTARTRTDGGTPLAERLAALTRPEQDRALLDLVRAQV
ASVLGHASAEQVEPAKAFKDLGFDSLTAVELRNRLGAVTGLRLATTLVFDHPSPTALARQ
LRTDLLGDADEAGQEGPQDLRGAAPGADDAIAIVAMSCRYPGGVRGPEELWRLVETGGDA
IAGLPGNRGWDTAELYAGQDGRTFAGGFLHDADSFDADFFGISPREALAMDPQQRLLLET
SWEAIERAGIDPSSLRGTRAGVFVGASAGGYDAQLERSADVDGVLGHVMTGNAGSVMSGR
VSYALGLEGPAVTVDTACSSSLVALHWAVQALRSGECSIALAGGVTVMSTPGTFSEFSHQ
GGLAPDGRCKAFAAAADGTGWGEGVGMLLVERLSDAQRNGHPVLAVVRGSAINQDGASNG
LTAPNGPSQQRVIRAALASAGLSAADVDAVEAHGTGTRLGDPIEAQALLATYGQDRADGQ
PLLLGSIKSNIGHTQAAAGVAGIIKMVMAMQHGVLPQTLHVDEPSPHVDWSAGDIALLTR
ATAWPETRRPRRAAVSSFGISGTNAHTIIEQAPEPADRPAPTATPVPVPYVLSARSPQAL
RAQAARLLPVAEEAVAADGSGLPDLAYSLATGRAGLEHRAAFAADDREGLLRALAGLAAD
ERPPGLIRGTVSGGGLAFLFTGQGSQRLGMGRALYATYPVFADALDRVCERFDLELPLKD
VLFGTDAEALDRTEYTQPALFAVEVALFRLLTSWGLRPDFLSGHSIGEITAAHVAGVLSL
EDACSLVAARGRLMQALPSGGVMIAVQASEEEVLPLLTDRVSIAAVNGPRSVVVAGDEDA
ALAVAEAFPDRKSKRLTVSHAFHSPHMDGMLADFRKVVEGLTFQDPRIPVVSNLTGSVVT
DEMGSADFWVRHVREAVRFLDGIRALEAAGVRTYLELGPDGVLSALAQDCLTEDAGFVPV
LRAARPEAEAVTATAALAHAYTRGVPLDWRAYFAATGTGAHRVDLPTYPFQPVRYWPEPA
APGGAAQTAPAAAGADARFWDAVERADLTALADEFDVEGDQPLSTALPALSAWRRDQQAR
AKAESLLYRVTWQPWSGPDRGTPAGTWIVPVPAAQAQDPWVRALTDRMSGDGARIVPLPL
DVADGDPAVLRAHLAAAGPVSGVLSLLALDERPHPEHPSVPVGLALTAALATALTSEPDA
DADQPGGHANAPLWCVTRDAVAAAPGDTLGGAAQSQVWGLGRVIALEHPDRWGGLVDLPE
VCDERALNRLSAVLTGAGDEDQLAIRAAGPLVRRLVHAAPSTGARTAPPWTPDGTVLITG
GTGALGRHVARHLAARGARRLVLVSRSGADAPGATEIRAELEALGAAVTLAACDVTDRDA
LEALVTRLAADDTPVRAVVHAAGVSQPPGTGTDLPGFARVVTAKTAGAVHLDALFDTPDS
LDAFVLFSSIAGVWGSGGQGAYAAANTFLDALAERRAARGLAATAIAWGPWADGGMATEG
DAEEQLTRRGLPPVDPGTNLLALERALAGRDAAVTVASVDWARFAPVFAAARPRPLVGDL
PEVRGVLREEPHAGAGTSADAAATVLGRLGELSGDERDTALLDLVREHAAAALGHPSADA
VAPDRAFKDLGFDSLTAVELRDRLGAACGLRLPSSLVFDYPNPQALTRHLLRTLFPEGSG
GAAVTDLDSDPQDAELRRTLATIPLGRIREAGLLDTLLRLAGPDTPATEPGAEAVDPGGS
IDTMDLQDLLDLALDGGGGLDDDTPDTTTSNSNF
>A0A2K8P6V3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces lavendulae subsp. lavendulae|TrEMBL
MTTSNEKIVQALRASLQETERLRRQNRKLTSDSHEPIAIVAMSCRFPGGVTSPEELWQLV
ADGGDAISGFPADRGWDLDALYDPDPDHAGTCYVRHGGFLDGVGEFDAGFFGISPREALM
MDPQQRLLLETAWEAFERAGIDPAALRGSRTGVFAGTNGQDYARLSTSPEDFDGYLGTGN
AAAVISGRLAYTFGFEGPAVTVDTACSSSLVALHLAAQALRKDECSLALVSGVTVMSTPG
AFMEFSRQRGLAADGRCKPFSAAADGTGWSEGVGMLLVERLSDARRNGHRVLAVVRGSAV
NQDGASNGLTAPSGPAQQKVIRQALANAGLTGADVDAVEAHGTGTSLGDPIEAQALLATY
GRDRPAGRPLLLGALKSNIGHTQAAAGVAGVIKMVMAMRHGVLPGTLHLDEPSPHVDWSA
GAVRLLTEPVDWPEGEGPRRAGVSSFGVSGTNAHVVLEQAAPDTEGAAAPAPVPDSRTPL
LWPLSARSAEALPEQARRLLAYVREHPRIPAADIARALATTRAGLPHRAAVVGRDHDELV
TALASFARHEATGHAFEGTAARKKKAAFLFSGQGSQRLGMGRELYAALPVFTEAFDAVCS
ALDAHLERPLREVVFGDDAELLNRTGYAQAALFAVEVALFRLVESWGVRPDLLAGHSVGE
FAAAHVAGVFSLDDAAALVAARGRLMQALPAGGVMVAVEASEEEVRGLLAGYEDRVAIAA
VNGPSAVVVSGAEEAVAEVVDRLSADGRKTKRLTVSHAFHSPLMDPMLDAFRKVAEGVTF
SEPDIALVSTVTGRPITAAEPADAGYWVRQVVRAVRFADTVAALSDAGASVFLEIGPGGV
LTALAQALLDEQPAVTLPVLRPDRPEDLAVASALARLHVHGVTPDWNALLGAPGPVLPDL
PTYAFQRRRYWLEGTAFSGQRTETGAADPAEDGFWQAVESADLEAFARRLDVADDAPLSS
VLPALTMWRRRNRERSTLDGLRYHTVWKPAATAATEIRLPGTWLVAVPAGHPTDEDPWVA
SALRALRDHGAEVRTVPVEPGTGRTDLADRLRTALDGTTAGGVLSLLAVDERPHPVHTAL
PEGLAATLALVQALGDAAPGASLWCVTRGAVSTGPSDPLRSPLQAQVWALGRTAALEHSD
RWGGLLDLPGELDDRAARRFAGALAGAHAAEDQLAVRAAGVLVRRLRRAPRAAAGPDGTT
TGWRPRGTVLITGGTGALGAHVARWLADAGAAHLVLTSRRGEAAAGADALRAELEERGAE
VTIEACDIADRTAVARLLDGLPGDHPLTAVVHAAGVGTPGMLAETTPERFADVLAAKAAG
ARHLDELLGDRPLDAFVLFSSISGVWGAAGQAAYAVANASLDALAEHRRSRGLTATAVAW
GPWAGGGMVEDGDAEERLRKRGLPALDPASALAALRGALDRDETAVTVADVAWERFAPSF
TLLRPSPLIAEVPEAAAALTAAAADPAPGGAGRGEATEFVRRTRTLTGPERARAVLALVR
GEAAAVLGHQDTDAVAADRAFRELGFDSLTAVELRNRLNKATGVHLPATLVFDHPSPAVL
AAHLLTELTTADTGESSGAARATAAARTSGDDEPVAIVAMSCRYPGDVRTPEDLWRLVAE
GRDAIGGFPADRGWDLESLYDPDPDRPGTTYAKDGGFLYDAADFDPQFFGISPREALAMD
PQQRLLLETSWEAFERAGLDPTSLRGTSTGVFIGSGYQDYAARLLSVPQDLEGYIGTGSS
GSVVSGRIAYSLGLEGPTLTVDTACSSSLVALHLATQALRRGECDLALAGGVTVMSSPNA
FIEFSRQRGLAADGRCKSFAAAADGTGWGEGVGLLLVERLSDARRNGHRVLAVVRGSAVN
QDGASNGLTAPNGPAQQRVIRQALADAGLAAADVDVVEAHGTGTRLGDPIEAQALLATYG
QDRPEGRPLWLGSLKSNIGHTQAAAGVGGIIKMVQAMHHGILPGTLHVDAPTPHVDWSTG
SVRLLTSAVDWTADGEHGRRAGISSFGVSGTNAHVIIEQAPPQPAAPTGTRPAPGVVPWL
VSGTSPAALRDQAERLLAHIEGHPELEPVDVALSLATTRAALEHRAVALGTDRGEFLPAL
RALAARDTTGPADPALRGTAATDRRTAFLFPGQGSQRLGMGRELYAAFPVFADAFDAVCA
HVDQYLERPLAGVVFGEDAALLDRTAYAQPALFAVEVALFRLVESWGVRPDFLAGHSVGE
FAAAHVAGVFSLEDAAALVAARGRLMEALPAGGVMVAVQASEDEVRDLLSGFEGRAGIAA
VNGPSAVVVSGAEDAVTKVVDRLSADGRRTKRLSVSHAFHSPLMDPMLDDFLKTVETVAF
GAPTLPVVSTLTGAPVPAEEFCSAEYWVRHVREAVRFADAVTALADLGVRTFLEVGPGGV
LTAMAQDSLDEDAVTSPLLRTDRPEGLAVTTALAHLHVHGTPVDWSAVLAGRGARRVDLP
TYAFQRSRYWLDTRPAAGDLASAGLRTADHALLGAAVALADGEGVVLTGRLSTAAHPWLA
EHQVMGAVLLPGTALVDLAIRAADEAGCDRVDELTLQAPLVLPSRGGVQLQVTVAGPDDT
GRRTVRVHSRPDGAGPDEPWSTHAVGVLATHAPEAAAPARPDPAADLSQWPPAAARPVPT
EGYYERLAELGFGYGPVFQGLRALWQRDGEVFAEVALPQDTTADGFGLHPALLDSALHAV
GLGGLLPDTGQGRIPFAWSGVRLDATGATGLRVRLTSPAPDTVSLLVADATGRPVASVES
LVLRAVTADQPATARRVEHQDTLYRMDWPALPLGEPGSTPDPTRVADHTGLLALLAAPGG
ADGLPALPDTVLIPAPHAPGDATAQDVREVTQHGLELLRTWLGDDRTAHARLVLLTRGAV
APVPGTTVTDPAQSALWGLVRSAQSENPGRLVLVDTDDPDGHGPSGRALHAALATGEAQF
ALRDGAAYVPRLARRSPGDGLRPAPGATAWRLTTGATGTLDDLALTENPAATAPLGRGQV
RIAVRAAGVNFRDALIALGMYPGAATLGSEAAGVVAETGPGVTGLAVGDRVFGMVPEAFG
PLAVADHRMVARIPQGWTFTEAASVPIVFLTAYYALVDLAGLKAGQSLLVHSAAGGVGMA
ATQLARHLGAEVYGTAGPGKWAALRADGLDEEHLASSRDLGFEQRFLAATGGRGVDVVLN
SLAGAYVDASLRTLTDGGRFLEMGKTDVRDPERTAAEHRGAAYTAFDTIEAGPERIGAML
RELVALFETGALRPLPVTCWDVRRAPDALRHLSQARHVGKLVLTVPAAPDPGGTVLVTGA
TGALGGLVARHLVTRHGARHLLLAGRRGPAAEGAAALRDDLLARGAETVTLAACDAADRD
ALAALLAGIPADRPLTAVVHAAGVLDDGLVATLTGDRLDAVLRPKADAALNLHELTRGLD
LSEFVLFSSVAATLGSAGQGNYAAANAFLDALAQRRAAAGLPATAIAWGPWADSGMASGM
DERGRGRMARSGLVSFRAEEGLALFDAARTGEDAVAVPVRFDTTAPATGPDPAGEVPAVL
RGLVRRTVRRTAREAVAAEGADALRERLGALSDPERDGVLLDLVRTQVAAVLGIGGPRDV
DRNREFKQLGFDSLTSVELRNRLNAATGLRLPATLVFDNPTPVALAERIRLDLVPDPAPG
ASALAVFGELDRLETALAAVGADDDLVRSRIRARLHGVLAALGEGTAADGSGGGSSPDEA
SDERLRSATVDDIFALIDQELDGA
>A0A2K8P9X6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces lavendulae subsp. lavendulae|TrEMBL
MLNESQDFAAEIDGAPEAGETQDISNSDSPQQWYEDLSGLTEGEQHTALLERVSALVIAA
LRDNAPTVLDPHRSFLDLGFDSLAAVDLHARLVAATGLRLPVTLAFDHPTPAHLARRIHA
LLLGLTTPAEAPVTAAISSDEPIAIVGIGCRFPGGVHSPEALWDLVASGTDAISAFPTGR
GWNLDSLYDPNPDRSGTSYAREGGFLHDADQFDAAFFGISPREALAMDPQQRLLLETSWE
AFDRAGVDPAALRGGQVGVFVGAETQEYGPRLEDATDGFEGYLVTGNAASVASGRIAYTF
GFEGPTVTVDTACSSSLAALHLAVQALRSGECSLALAGGVAVMASPGSFVSFSRQRGLAP
DGRCKPFAAAADGTAWGEGAGMLLVERLSDARAHGHRVLAIVRGTAINQDGASNGLTAPS
GPAQQRVIRQALANAGLTAADVDAVEAHGTGTKLGDPIEAQALLATYGQDRPADRPLRLG
SLKSNIGHTQAAAGVAGVIKMVMAMHHGLLPKTLHVDAPTPHVDWEAGAVSLLTEPVEWP
ATGTPRRAGVSSFGMSGTNAHGIIEEPPAEDRETAGETGAADRPSGQTAGEAGEPSGPLP
WALSAKTPEALRAAARRLADWLDTHPDADPLDIGHSLAANRGRFDHRAVVLGDDRAALRR
GLHALADATDTPAVVHAAPATGRTAVLFTGQGSQRLDMGRELYETQPVFADALDDACWYL
NEQLDTPLLDVLFAEEGTPEAALLHQTGYTQPALFAIEVALYRLVESWGVKPDFVAGHSI
GEIAAAHVAGVFSLDDACALVAARGRLMQALPGGGVMIAVQASEDEVLPLLTERVSIAAV
NGPMSVVIAGDEDAAVAVVEAFADRKSKRLTVSHAFHSPHMDAMLDEFRRVAQVLDYAAP
TLPVVSLLTGTTATAAELADPEHWVRHVREAVRFLDGVRTLRARGADSFLELGPDPVLTA
MAHDCLVTDPQDPANPGFASALRAGRSEPATLLDAVARMFVRGTDVDWAACYAGTGARSV
ELPTYAFQRQRYWMNSRTAETESAHTSGYGSDPADTEFWDAVEHQDVAALAAALELDADG
EQPLSEVVPALSAWRRRVRTQSEVDGWRYRDTWKPVADSVGGARLSGVWLVVVPAGGVDD
SAVVEGLAARGAEVLRVVVEGGAVRAALAGATGPVAGVVSLLALDEAAGVVPSAELVQVL
GEAGVGAPLWCLTRGAVSVGRSDRLVSAVQAQVWGLGRVAALEVPERWGGLVDLPEVWDE
RVMGRLAGVLAGGFAGEDQVAVRASGVFGRRLVRAAAGGSGSWVPSGTALVTGGTGALGG
RVARWLAGAGAARLVLTSRRGVDAPGAAELAAELAETGVEVSVVACDAADREALRELLAA
EAETLTAVVHTAGVLDDGVLEALTAERFEGVLRAKAVSALNLHELTVELGIELSAFVLFS
SMSGTIGAAGQGNYAAANAYLDALAEQRRAAGLAATSLAWGPWAGSGMAADEAMDARMRR
DGVPPMAPDAAIAALAQAVGAGETALTVADIAWDRYAAVVAAVRPNPLIRDFVTVAAAGE
AAITGHGTVVTGADVAGATFAKLAELPRAEQERELLALVRTQVAAVLGHEGSDAVGAERA
FKELGFDSLTAVDLRNRLGAASGLKLPTTLVYDYPTSAALAEYLRGELVGSAPTVDAALP
MAVETDGDPIAIVAMSCRFPGGVRTPEDLWRLLAQGTDAVAEFPVDRGWDLERLYDADPE
RPGTSHTREGGFLYDVADFDADFFGISPREALAMDPQQRLLLETAWEAFERAGIDPAALK
GSRAGVFVGTNGQDYLSLVAGEADGLEGHVGTGNAASVVSGRLSYVFGLEGPAITVDTAC
SSSLVALHLAVQALRQGECTMALAGGVTVMSTPDAFVDFSRQRGLAEDGRIKAFAEGADG
TGWGEGVGMLLVERLSDARRNGHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRQALA
SAGLSAAEVDVVEAHGTGTKLGDPIEAQALLATYGQDRAEGRALLLGSIKSNIGHTQAAA
GVAGVIKMVLAMRHGVLPQTLHVDAPTPHVDWTAGEVELLTESMEWPETGRPRRAGVSSF
GLSGTNAHTIIEQAPISEAEEVAAPDAPTRGTAPVLPVVVTGKNPAGLRAQAAQLATWLS
GDPQAALADTAYSLAAQRSKFETRAVLLAGSEGHEALTAGLRGIAAGDQVPGLVQGEVAG
GGLAFLFTGQGSQRLGMGRELYETFPVFADALDAVCARFDSRLDVPLMDVIFGAEGETLD
RTEFTQPALFAVEVALFRLVEAWGVTPDFVSGHSIGEIAAAHVAGVLSLEDACALVAARG
RLMQALPGGGVMIAVQASEDEVLPLLTDRVSIAAVNGPRSVVIAGDEDAAVAVVEAFAGR
KSKRLTVSHAFHSPHMDGMLDDFRQVVEGLTFAAPRIPVVSNLTGSIVSDEMDSAEFWVR
HVRDAVRFLDGIRALEGAGVTTYVELGPDGVLSALAQECVNEDAVFVPVLRKDRAEAESL
VRAVAQAFVRGAKVDWSAFFAGTGARRVELPTYAFQRRRFWPEPVLAGGSPARALADAGA
DGVDARFWDAVERGDLVTLLSELEVEDDASFSDFVPALSAWRRQTQEQAQVDGWRYRVSW
KPLTAAALSSGAPRGAWIVVVPGAAEDDALAAAVVEGLAARGAEVLRVVVEGGAVRAALA
GATGPVAGVVSLLALDEAAGVVATAALVQALGDAGVGAPLWCLTRGAVSVGRSDRLVSAV
QAQVWGLGRVAALEVPERWGGLVDLPEVWDERAMARLAGVLAGGLAGEDQVAVRSSGVFG
RRLVRAAAGGAGSWVPSGTVLVTGGTGALGAHVARWLAGAGAERLVLTSRRGVDAPGAAE
LAAELAETGVEVSVVACDAADREALRELLAAEAETLTAVVHTAGVLDDGVLEALTPERFE
GVLRAKATSALNLHELTVELGIELSAFVLFSSMSGTIGAAGQGNYAAANAYLDALAEQRR
AAGLAATSLAWGPWAEGGMAADDALEARMRRDGVPPMDAQRAIRALRQAVGAHDVAVTVA
DVEWERYLSHHTAVRPSPLFGQLSDVRENRSAQSASGAHGQAHADAGRPLTLSGRLAVLA
PAEQERELLDLVRTHVAAVLGHGGAEAVGAERAFKELGFDSLTAVELRNRLGAATELRLP
VTLVYDYPTSAALAEYLRIELVGSVSVSGALLPVASAVDGDPIAIVAMSCRFPGGVRTPE
DLWRLLAQGTDAVAEFPADRGWNLDRLYSPDPDQAGTSYAREGGFLAGAAEFDADFFGIS
PREALAMDPQQRLLLETAWEAFERAGIDAGTLRGSQAGVFIGTNGQDYLSLVAREQDGLE
GHVGTGNAGSVMSGRVSYVLGLEGPAVTVDTACSSSLVALHWAVQALRQGECTMALAGGV
TVMSTPENFIDFSRQRGLAEDGRIKAFAEGADGTGWGEGVGMLLVERLSDARRNGHPVLA
VVRGSAINQDGASNGLTAPNGPSQQRVIRQALASAGLSAAEVDVVEAHGTGTKLGDPIEA
QALLATYGQDRPEGRPLLLGSIKSNIGHTQAAAGVAGVIKMVLAMRHGVLPQTLHVDAPT
PHVDWSAGEVELLTESMEWPETGRPRRAGVSSFGISGTNAHTIIEQAPDAEPSETPDALP
AVRPAGVLPYLLSGKTKEAVRAQAAALTAHLEAADGAGHPDALDLAYSLATSRAHLDHRA
GIVLVADAGDDGEGLRDALTRLAAGEPTPRTTTGTAGDGRTAFLFTGQGSQRLGMGRELY
EAFPVFADALDAVCARMDGHLELSLREVMFGADAELLDQTGYTQPALFAVEVALFRLVEA
WGVTPDFVSGHSIGEIAAAHVAGVLSLEDACALVAARGRLMQALPGGGVMIAVQASEDEV
LPLLTDRVSIAAVNGPRSVVIAGDEDAAVAVVEAFAGRKSKRLTVSHAFHSPHMDGMLDD
FRQVAEGITFAAPRIPVVSNLTGALVSDEMGSAEFWVRHVRDAVRFLDGIRALEGAGVTT
YVELGPDGVLSALAQECVNEDAVFVPVLRKGRAEAKSLVGGLAQVHAEGVDVDWSAFFAG
TGARRVDLPTYAFQRQRFWPSAVAFAGGDPESIGLGDAAHPLLGATVALADSGGVLLAGR
LSLETHPWLADHVIHGGVLLPGTAFVELALCAGDQVGCDVVEELTLEAPLVLPERGGVQL
QLVVEAPAVGGGRAFAVYSRRQDVVGEELWTRHGSGVLASGARSEAAAEFGELAVWPPVD
AVPVDVSGLYAELAEGGVSYGPLFQGLKAAWRRGDDLFTEVLLPEDGRRDASRFGLHPAL
LDAGLHAIGHGDPSGQADSGALLPFSWAGVSLYAVGASALRMRLVATGAGDQRALALWVA
DGSGRPVAAVESLTLRPASAEQVNAAGAAHVESLFRVEWTAAAPQEAPVGELRWAVLGRD
EMGLGSTGVVQVTEYADVDAFAVALEAGEPVPDAVFVAPSVGVSAEGVVEAVHGAVGAAL
ELVQGWLADERFAGMRLVWLTSGAVAVGAGAGVRDLAGGAVRGLLRSAQSENPGQLVMLD
LDVDLDGDGVGAVAAALASGEPELAIRAGVVSVPRLVRVLSSESGAGAEAGFGPSGTVLV
TGATGSLGRLFARHLVTAFGVERLLLTSRRGPAAEGADELVAELVGLGAHVDLVACDIAD
RDALAAVLDGVSAEYPLTGVVHTAGVLDDGVLASLTAERVAGVLRPKVDAAWNLHELTRG
LDLDAFVLFSGAAAAFGAAGQASYAAANAFLEGLAEQRRAEGLPATALAWGLWAPQSGGS
GMAGRLDEVDLRRIARDGVGALAADEGLALFDAAMVVDAAVLLPMHLDVAVLRAQAVAAG
STPALLRALVRVPARRMVERRDGGAEGGSPLVARLMGLPVAEREGVLLELVCGRVAVVLG
HSGAGAVDAERAFRDLGFDSLTAVELRNVLKAETGLRLPPTLIFDYPTPVALARHLLAEL
AVTSGAGDRVEHGRRTPVRIAAGVADDPIVIVGMGCRFPGGVRTPEDLWQLVASGGDGIT
AFPTDRGWNGEALYHPDPDHAGTSYTREGGFLHEAAEFDPAFFGISPREALAMDPQQRLL
LETSWEAFERAGIDPMSMRGSRTGVFAGVMYHDYVSGIGIGDGAGAGDELPEGVEGYLGT
GNAGSIASGRIAYTFGLEGPAVTVDTACSSSLVALHWAIQALRNGECDMALAGGVAVMAT
PETFIDFSRQRGLATDGRCKSFAEGADGTGWAEGAGMLLVERLSDARRHGHPVLAVVRGS
AVNQDGASNGLTAPNGPSQQRVIREALAGAGLSTADVDAVEAHGTGTRLGDPIEAQALLA
TYGQERAEGRPLLLGSIKSNIGHTQAAAGVAGVIKMIMAMRHGVLPKTLHVDAPSSQIDW
EAGDVRLLTDAVEWPETGRPRRAGVSSFGISGTNAHTIIEQPPVTHVTEVPGVGVALPMV
PWVLSAKGEDALRAQARQLESYVLSAVDARPLDVAWSLASGKALFEDRAAVFAADREGLL
AGLAALADGRTSAGVVEGSPVSGKLAFLFTGQGSQRLGMGRELYDTFPVFATALDEVCAR
FELPLKDVLFGTDAGLLDETRYTQPALFAVEVALFRLVEAWGLKPDYLSGHSIGEIAAAH
VAGVLSLEDACALVAARGRLMQALPAGGVMIAVQASEDEVLPLLTDRVSIAAVNGPRSVV
IAGDEDAAVAVVEAFADRKSKRLTVSHAFHSPHMDGMLDEFRQVVEGLSFAAPRIPLVSN
LTGSLVSGEMSSAEFWVRHVREAVRFLDGMQALEAAGVTTYLELGPDGVLSALAQDCLTG
DADTAFLPVLRAGRVEAETFVGAVAQAHVRGVEVDWSAFFAGTGARRIELPTYAFQRQRY
WLQLTGAAARNGLAGDLDSRFWDAVEREDMESLADTLEMEDEGAWSSVLPALSAWRRGLR
TQSEVDAWRYRVSWKPLTDSVGGARLSGVWLVVVPAGGVDDSAVVEGLAARGAEVRRLVV
EAGTDRAALAGLLTGAGPVAGVVSLLALDEAAGVVPSAELVQVLGEAGVGAPLWCLTRGA
VSVGRSDRLVSAVQAQVWGLGRVAALEVPERWGGLVDLPEVWDERAMGRLAGVLAGGLAG
EDQVAVRSSGVFGRRLVRAAAGGAGSWVPSGTVLVTGGTGALGGRVARWLAGAGAERLVL
TSRRGVDAPGAAELVEELGVLGVDVSVVACDASDREALRELLAAEAETLTAVVHTAGVLD
DGVLDALTPERFEGVLRAKAVSALNLHELTVELGIELSAFVLFSSMSGTIGAAGQGNYAA
ANAYLDALAEQRRAAGLAATSLAWGPWAGSGMAADDALEARMRREGLPPMAPDTAMAVLR
QSVSSSGDAALLVADVDWERFGPAFTAVRPSTLFAELPETRPAGTAARAESVGAPVGKFA
GLGAAELERELLGLVRAQVAAVLGHDGADAVGAERAFKELGFDSLTAVELRNRLGAVTGV
TLPATLIFDYPTASALTAFLRDELLGNQAEIAGPVVVAGPALDDDPIAIVAMSCRFPGGV
RTPEDLWRLLSEGGDAIGEFPADRGWDLERLYNPDPDQQGTFYAREGGFIYDVADFDADF
FGISPREALAMDPQQRLLLETTWEAFERAGIDPATVRGSQAGVFVGTNGQDYDGTFQVIP
EGIEGFLGTGNAASVVSGRLSYAFGLEGPAVTVDTACSASLVALHWAVQALRNGECSLAL
AGGVTVMSSPGAYIDFSRQRGLAADGRIKAFAAGADGTGWGEGVGMLLVERLSDARRNGH
PVLAVIRGSAINQDGASNGLTAPNGPSQQRVIRAALASAGLSAAEVDVVEAHGTGTRLGD
PIEAQALLATYGQERSAHEPLLLGSIKSNIGHTQAAAGVAGVIKMVLAMQHGVLPQTLHV
DEPTPHVDWTAGDIEILTERRDWPETGRPRRAGISSFGFSGTNAHTIIEQAPEVEQTEPA
GLPQARPGGLPWVLSAKSEAALRVQAERLGAWFASNEDLASPADVAYSLATSRSALEHRA
TVVAEEPAAFAAALNALAAGEPVPGLVRGTASSGGLAFLFTGQGSQRLGMGRELYEAFPV
FADALDAVCARMDGHLELPLRDVVFGTDAELLDQTGYTQPALFAVEVALFRLVESWGLKP
DFLSGHSIGEIAAAHAAGVLDLDDACRLVAARGRLMQALPAGGAMIAVQASEDEVLPLLT
DRVSIAAVNGPTSVVIAGDEDAAVKVAEAFVAQGRKTKRLTVSHAFHSPHMDGMLADFRK
VAEGVTFAAPRIPVVSNLTGALVSDEMSSAEFWVRHVRDAVRFLDGIRALEGAGVTTYVE
LGPDGVLSALAQECVNEDAVFVPVLRKDRAEAESLVRAVAQAFVQGAKVDWSAFFAGTGA
RRVDLPTYAFQRQRFWPSAVAFAGGDPESIGLGDAAHPLLGATVALADSGGVLLAGRLSL
ETHPWLADHVIHGGVLLPGTAFVELALCAGDQVGCDVVEELTLEAPLVLPERGGVQLQLV
VEAPAVGGGRAFAVYSRRQDVVGEELWTRHGSGVLASGARSEAAAEFGELAVWPPVDAVP
VDVSGLYAELAGDGMAYGPLFQGLKSAWRRGTELFTEVALPEEGHQDAARFGLHPALLDA
GLHAIGHGDPAAAETGAQLPFSWAGVSLYAVGASALRMRLVATGAGDQRALALWVADGSG
RPVAAVESLTLRPASAEQVNAAGAAHVESLFRVEWVAAGAGAPVEAADLRWAVLGRDEFG
LGTTDAQVTEYADVDALVVALEAGEPVPDAVFVAPSAGVSAEGVVEAVHGAVGAALELVQ
GWLADERFAGMRLVWLTSGAVAVGAGAGVRDLAGGAVRGLLRSAQSENPGQLVMLDLDVD
LDGDGVGAVAAALASGEPELAIRAGVVSVPRLVRVLSSESGAGAEAGFGPSGTVLVTGAT
GSLGRLFARHLVTAFGVERLLLTSRRGPAAEGADELVAELVGLGAHVDLVACDIADRDAL
AAVLDGVSAEYPLTGVVHTAGVLDDGVLASLTAERVAGVLRPKVDAAWNLHELTRGLDLD
AFVLFSGAAAAFGAAGQASYAAANAFLEGLAEQRRAEGLPATALAWGLWAPQGRNGAAGA
GMAASLDEANLRRIAREGVAALAAEEGLALFDAAMVVDAAVLLPMHLDVAVLRAQAVAAG
STPALLRALVRVPARRMVERRDGGAEGGSPLVARLMGLPVAEREGVLLELVCGRVAVVLG
HSGAGAVDAERAFRDLGFDSLTAVELRNVLKAETGLRLPPTLIFDYPTPVALARHLLAEL
ALTTGADEQNLGRGQLMARVRPVTGVVDDPIVIVGMGCRFPGGVRTPEDLWQLVASGQDG
ITAFPTDRGWNGEALYHPDPDHAGTSYTREGGFLHEAAEFDPAFFGISPREALAMDPQQR
LLLETSWEAFERAGIDPTSMRGSRTGVFAGVMYHDYATGYGNGEELPEGVEGYLGTGISG
SIASGRVSYAFGLEGPAVTVDTACSSSLVALHWAIQALRNGECDMALAGGVAVMATPETF
VDFSRQRGLATDGRCKSFAEGADGTGWAEGAGMLLVERLSDARRHGHPVLAVVRGSAVNQ
DGASNGLTAPNGPSQQRVIREALAGAGLSTADVDAVEAHGTGTRLGDPIEAQALLATYGQ
ERVEGRPLLLGSIKSNIGHTQAAAGVAGVIKMIMAMRHGVLPKTLHVDAPSSQIDWEAGD
VRLLTDAVEWPETGRPRRAGVSSFGISGTNAHTIIEQPPVTDVTEASAEAAPLPVVTWTL
SAKGEDALRAQARRLQSFVLSTPDVRPVDVAWSLASGKALFEDRAAVFAADREGLLAGLA
ALADGRTSAGVVEGSPVSGKLAFLFTGQGSQRLGMGRELYDTFPVFATALDEVCARFELP
VKDVLFGTDAGLLDETRYTQPALFAVEVALFRLVEAWGLKPDYLSGHSIGEIAAAHVAGV
LSLDDACALVAARGRLMQALPSGGVMIAVQASEDEVLPLLTDRVSIAAVNGPTSVVIAGD
EDAAVAVVEALSDRKTKRLTVSHAFHSPHMDGMLDDFRQVVEGLSLTAPRIPLVSNLTGS
LVSDEMSSAEFWVRHVREAVRFLDGMQALEAAGVTTYLEIGPSGVLSALGQECVSGETAG
FVPVLRSGRPEPETAVAALAKAHVRGAEVDWSAYFAGTGARRIELPTYAFQRQRYWLEMP
AAPAARRGAGDDMDSRFWDAVEREDMESLAAALDLDDENAWDTVLPALPALSAWRRGLRT
RSEVDAWRYRVSWKPLTDSAAGTGLLGTWLLVTPAGDVDDTAVAGALAARGAEVHRVQVA
PGTDRGALGGLLTGAGPVAGVVSLLALDEAAGVAPTAGLLQAMGDAGVGAPLWCLTRGAV
SVGRSDRLVSAVQAQVWGLGRVAALEVPERWGGLVDLPEVWDERVMGRLAGVLAGGFAGE
DQVAVRASGVFGRRLVRAAAGGAGSWVPSGTVLVTGGTGALGGRVARWLAGVGAERLVLT
SRRGVDAPGAAELAAELAETGVEVSVVACDAADREALRELLAAEAETLTAVVHTAGVLDD
GVLEALTPERFESVLRAKATSALNLHELTVELGIELSAFVLFSSMSGMTGAAGQGNYAAA
NAYLDALAEQRRAAGLAATSLAWGPWAEGGMAADDALEARMRREGLPPMAPDTAMAVLRQ
SVGSSDGAALLVADVDWERFGPAFSLVRPSTLFAELLETRPAGSADRPEVAGSPVDRLAG
LGAAELERELLGLVRAQVAAVLGHDGADAVGAERAFKELGFDSLTAVELRNRLGAVTGVT
LPATLIFDYPTASALTAFLRDELLGTQAEIAGPVAIATDDDPIAIVAMSCRFPGGVRTPE
DLWRLLSEGGDAIGEFPADRGWDLERLYNPDPDQQGTFYAREGGFIYDVADFDADFFGIS
PREALAMDPQQRLLLETTWEAFERAGIDPATVRGSQAGVFVGTNGQDYGAMLQTVPDGIE
GFLGTGNAASVVSGRLSYAFGLEGPAVTVDTACSASLVALHWAVQALRNGECSLALAGGV
TVMSSPGAYIDFSRQRGLAADGRIKAFAAGADGTGWGEGVGMLLVERLSDARRNGHPVLA
VIRGSAINQDGASNGLTAPNGPSQQRVIRAALASAGLSAAEVDAVEAHGTGTTLGDPIEA
QALLATYGRERTDGQPLFLGSIKSNIGHTQAAAGVAGVMKMVLAMQHGVLPQTLHVDEPT
PHVDWTAGDIEILTERRDWPETGHPRRAGISSFGFSGTNAHTIIEQAPSAEDLTPEPAPQ
QRPVPVPWVLSAKSEAALRVQAERLAARLGSDDAPYTPADVAYSLATSRSALGHRAVVVA
QEREEFLTALKALAIGEQPTGAVRGTASSGGLAFLFTGQGSQRLGMGRELYDAFPVFADA
LDAVCARMDGHLELPLRDVVFGTDTELLDQTGYTQPALFAVEVALFRLVESWGLKPDFLS
GHSIGEIAAAHAAGVLDLDDACTLVAARGRLMQALPAGGAMIAVQASEDEVLPLLTDRVS
IAAVNGPTSVVIAGDEDAAVKVAEAFVAQGRKTKRLTVSHAFHSPHMDGMLADFRKVAEG
VTFAAPRIPVVSNLTGALVSDEMSSAEFWVRHVREAVRFLDGMRALEAAGVTTYLELGPD
GVLSALAQDCVTEDAATFAPLLRKGRAEAEALVTALARAHAHGVAVDWSAYFAGSGARRV
DLPTYAFQRKRYWLEEAHRPSAAGSDAAGGAAVDAPFWEAVENADLAALTATLDIDADQP
LSALLPALSAWRHRRTEHSVVNTWRYGVTWKPLPAADVSARPSGTWLVVTPVAGADSGLP
AVADALRAQGADVREVALDPAVTDRGGVADRLRTALAGDREAAGVVSLLALAEAPHPAHP
AAPAGVLLTGTLVQALGDAEVDAPLWCLTSGAVATGPADRVRSAAQAQVWGLGRVIALEH
PERWGGLVDLPAAADGRTLDRLLAVLGGADAGGAEDQIAVRASGLLVRRVEHAAATPAAT
GADAGARPASWRARGTVLVTGGTGALGAHVARWLAAHGAEHLVLAGRRGAQAPGTQALLA
ELAALGVRATAVACDVSDRQSVSELLAALREDTSAPALTAVFHTAGVGQLTPLAESGPDE
VASVLAAKAAGADHLDELLGDTELDAFVLFSSIAGIWGSGGQGAYAAANAHLDALAQRRR
DRGLTATAIAWGPWAEGGLVADDEAAGQLRRRGLPVMAPDRAVAALQQALDADDTNVTVA
DVDWDLFVPAFTASRPRPLIADLPEVLRVLDAERQAAGPGTDGDGAAAEADRLVAELRGM
GAEEAERTLLGLVRGHVAAVLGHEGAATVEAGRAFKELGFDSLTAVELRTRLGAATGLRL
PAALVFDHPTPAALAAHIRAELLGEDTEPALPALAEIDKLEYVLSSVPGEDAAERARVTA
RLEALLANWNRTERAALAQEDEETVIESASAEDLFDIINNEFGKA
>G7LSJ4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Brenneria sp. EniD312|TrEMBL
MTHGKNNNAAKNTGVDQGTTEQRLMDALRHSLLQNEQLKQSNQNLTQAAHEPIAIISMGC
RLPDGIHSPEQLWQRLSDGEEAIDSFPADRGWNVDTLFEQNPELRAIANTWRGGFLEDAA
GFDAGFFKISDREALAMDPQQRLLLEVSWEVLERAGIVPATLKNSQTGVFIGATHNGYLS
DIERRNPAADGYRLQGSLSSISSGRIAYALGLNGPAITVDTACSSSLTAIHQAIHSLRNG
ECSLALAGGATIMASPEVFAEFTRQGGLAADGRCKAFSDHADGTGFSEGIGLILLEKLSD
ALRSGHNVLAVIRGSAINQDGASNGLTAPSGPAQEQVIRQALKNAELTFSDIDVVEAHGT
GTTLGDPIEAHALLNTYGKHRSDDQPLWLGSLKSNIGHVQLAAGVASIIKMVMALQHGRL
PKTLHAETPSSKIEWSRGNVKLLNMARDWPDTRRPKRAAVSSFGFSGTNTHIILEEAPPL
TPLAEETAPTSAFAAPGIALPLSATSPAGLCAQAKQLHTWITQNTDEEPDLTAIAYSLAT
TRSHFDYRAVITAEDSKNALNALEELAANHYAPGVIQGVRSPSGNVAFLFTGQGAQWPTM
GQGLYHMSPVFAQTLDEVCRYLDPLLPQPLKTVMFAEKSSADALLLDRTDFTQAALFAFE
TALCRTVMHLGVQPDVLSGHSIGEITAAYIAGVFTLADAATFVATRGRLMESITVDGAMV
AIEASETEVLPSLQGYEACVSIAAINAPSSVVISGDTNTVLSIAEQWQSRGYRTHRLRTS
HAFHSPHIDSIVDTLRRTLSALSFQAPAIPIVSTVTGQRLTNEQACSVEYWANQARCAVR
FDAAVQWLETHNIVAALEIGPDGVLTALGRASTTRESSGIPSTAWIASLRKDRDECRPFF
AALAKLYAQGKPLDWRKLLVQTLTVPLPTYPFQHRRYWLQAPSARPTFDGGLFAVNHPFL
HAGIRLAGEQGWVFTGLLDAAKQPWLLEHVVGDVAAVAGTVTAELMLYVGELIGCQRLDD
LTLQTILPIEKQVPAHIQLRIGEPEANGGRQADAYFYLSSPEQTHDQMPIWQRYATCYLV
PDHSTPPEWTDLRSPNWPPADAKQVDFSPLYEQLAEQGVVLGESFQQLTNVWEHDNNLYV
EATLAPIQGEQAGDFILHPTILDAGMQAALIEKLDVETENNQPRLLFYISGLRPYAKNVQ
RLRGHLVRKPLTSSSLGYREYSLRLADDTGRAVAVVDAIVLKSSPPSRIEPSRPPFYHLE
WREIKPDSSNTKPKIRWIVPQNKQVDRFSSLIKEYDTTSAYDDDIHQVLAAFSPQQDEIA
VFIAPDGDDTSEFIDHSPTHCVLNALQAWINDHRTTDVPLLVVTQGAIATNDGENVPNLS
QSPLWGLVRTAQLEYPGRFFLLDINEVENASLHLINTAINALSHEPQLSLREGKILAPRL
LKAVGDGDFTAYGHADRPENQCRNLNPDGTVLITGGTGALGKVIAKHLVEHHGIRHLLLA
SRRGKTAPGANALLKDLAELDAQVTIVACDIADMSAVASLLDAIPTAHPLTAIIHTAGSI
DTATLKTMNAEQIDSVLLSKAVSAWCLHRLTRHHELAAFVLYSSAVSILPQKGQGNYAAA
NAFLDALAYHRHHQGLPATSMAWGMWAERSEMGEQLGDEDIQHIIATGQIPLSRSQGLAY
LDTVVGTHVTNHPPLLIPARLNLEALREQGNIPLLSEALPRRTASRSDVGSSLQIADMLE
KERLPYLLKLIIQYAGEVLDHSDPKSIRTDIEFITLGFDSLTSVEMGSRLSLTLGVRIPA
TAIFDHPTPQVLAQYLLNMLIGEKHTVSTEVRTDAKKDSGRFYHLLRQAVQENLTQEGLS
VLAGAARLREHFSHQQHEQHAPETIWLRNDREKPLLVCLNSFIPAAANLTYQRLSSALSD
QYSTLTVPLPGYHGEPLPATDYAAAAALATAIERSVSERDFTLVGFSTGGLVAHAAAHQL
ESRGRQPKAVVLIDSFPPSAMNETAMADVLRTWFAAKGEFWSDEDTSVMAMAWYLELFGR
QWMPTHLKTPTVMLQAKDYPASAQPEQWANEWPNLVKSIITPGSHFELLTEYAVHTAKNL
SDLLCETEEKSDNTIGNEKEPKE
>A0A1Q2ZE90|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MGHEADGKDSASVPVAWVLSARTGAGLAARAARLSSQVRSDPGTPETEIGARLVAGAASS
GERAVVVDDTREGLLAGLDALAVGREAPNLLTGTGEAGRRVVFVFPGQGTEWPGMAVDLL
RSEPVFAERVRACERALAPYVDWSLEEVLTGCDSAPPLDRVDVVQPVLFATMVSLAALWR
SFGIEPAAVVGHSQGEIAAAHVAGALSLEDAARLVALRSRALDAIRGDGAMVTVMGSGGQ
AREMLSGQEGRLWVAAVNGPGALTVSGGLEALTGFESALSAARILRWRLPGVDFAAHSGQ
VEAIRDEVLRLSKETRPCDTAVGFYSSVTAGRIDPAELGGDYWYRNLRETVRFHETVTAL
LADGYDAFVECGPQPVLNLGLQETADQAGIPVSLLASLRRGEGGMRRFVTALADAHVHGV
PVDWRRLYGKAGQGASC
>A0A5K1I5U9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Halomonas lysinitropha|TrEMBL
MSRRVAIIGAAHRFPGTTPEAFWQDLKAEKDLVTHVAEDRWSQEAFRHPDRRHPGTSVSF
AAGTLGDIACFDAGFFSISPREAAHMDPQQRMLLELAWEAIEGAGLPASQLRGSNCGVFV
GIASLDYSYRMTDDMAAIDASTATGNTSSIASNRLSYMFDLHGPSMSIDTACSSSMVAFH
QACQAIRSGETDMALAGGISLHLHPYGFIIFSKASMLSANGRCRVFDESSDGYVRSEGAG
LFLLKDYARAMADGDPILAVVAGSAVNTDGHKSGLTVPNPEAQVALMRQAYQQADICPDE
IDYLEAHGTGTAVGDPIETRAIGEALAQHRTSPLPIGSVKSNVGHLETASGVAGLAKALY
SLRHREVPATIGIRKLNPNIRFNEWNLEVVTRARPLKPRGRLVIGVNSFGFGGANAHVIL
ESPPQAAVTVPPQASGPLPLRLSAHGEPALRALASRLTAWLGESDDDLYDIAHTLYCRRD
PLRDGALLFAEDKAEAAAMLAAFADPDREDPADIACGVRLTKPSAPAFVYTGNGCQWERM
GADLLAGSPVFAAAVDEVDALFRRHGDFSLRAELEGRHHEGPDGGSRMALTEIAQPSLFA
IQVGLTRLLQHHGIEPAAVTGHSVGEVAAAWACGALSLPDAVKVIYYRSHYQGKTRGQGE
MSAVAMSADEIRELLAEGAHEGVTLAGINSPKGVTLAGDPEALSRLERQLEARGIFVRRL
PLDYAFHSPAMDPIEAGVIASLADIAPQTERLPYISTVTGARLAGVELAAEYWWQNIRQP
VRFDAAIRSLVDEGTRLFIEIGAHPILRRYLSDALHGVGDDGLVLGTLEREQPAQACLTR
TVGQALLSGMPHSDERWFPVKGRLVDLPRYPWQRERYWVAPTGDSQGLLDRYYEHPLLGY
RLAQQPDTWESQLDTGRLPWLGDHVVGDAAVFPGAGFVELALAAARHRGDSALVDIEELE
IRAPLMLDAPHGRRMRLHFAPQDGRIEIRSREPLAEDEWQLNAVARVMEQSRGFLLRRAA
PVLPVRRPDITLSDHLAEAERLGLRYGPAFQAISEAWREGDSILGRIAPPAALHEGLDTQ
YLHPGILDSAFQLFIPLLAREARDAGIEDDGLAFVPVRVGRLQYLAEAGTPAVARARLGK
RAPHSFTADFELFDDQGRAVAVLSETRFKAIRLRRQRHQHVSYLDVRLTPAPRRNAIEAL
EPEALYAAMPGLIDDFARLTGQRYATEVAPLLDGLADAFAARAVRRLAGGGDLSHGRYRE
LSRAHLGAAPLLDQLLRQLEAAGRLQATEHGWRPSDADSVEPEAIWQLLVRDYPDYFPPV
QRLGRFGLHLDGLLSGEENAATLGLDADVLAQLTQQLPGAAGWQAIAGALQQALPRVLAA
LPPGQRLRLLEAGSAAPALGERLCDLLDPDCCDYTALTVGEQAHHQAEQLRERFPLIDVE
SLDAPADYRPPRAQLALVSLEPGHRERSRRLLESLAPRLAPGGQLLVLGIQPSAWLDTLL
ATPGLEDDGARLEATEQADVIAELEALGAEDIQALPLEGEAPGVYLIHARWAPAQPAERT
PVEPNQDTAPAIQLVTDAAHRELARRLAAGLQARGRQATITDAYHDRDGATHCVDLRQGE
ARCEHALAWAHDLEPLGEAASLWLITRGVAEMWVNGEWSKVRSEESGVRGEGSGVNGEEL
PGPDAALWGFGRSLANEANGYAVRLLDLPQGELDEAVIDALLDELTAPDAETEISLDARG
RRFATRLRSLPVPGPSPEAGQPARQAMSLGFELPGQLRHLAWRPHPLTEPDRDEVEVRVQ
ASGLNFRDVMFTLGLLSDEAIENGFAGPTLGLEFSGVVAAVGPGVEDLAVGDAVVGFGPA
SFSDRLVARRQAVAPIPAGVSFAAAATIPTTFFTVYYALKHLARLAPGEHVLIHGAAGGV
GIAAIQVAQWLGAEIHASVGSAEKRDFLRLMGIERLYDSRALTFAEEILEATDGRGVDVV
LNSLAGEAINQNLRSLRPFGRFLELGKRDFYENTHIGLRPFRNNLSYFGIDSDQLMKERP
ELTAELFGEMMALFQDGTLTPMPYTAFSSQQVVEAFRYMQQARQIGKVVVTHEQALTPNS
TPRPGSERLTLPAEASYLVTGGLGGFGLASARWLASRGARHLILVGRSGAASDEARAGVA
ALEAQGVEVVAAACDITDRAALTRLLDECRNRLPPLRGVIHAATVIDDGLIRNLDPERIR
RVLAPKIEGARHLDALTRHERLDFFVMYSSATTLFGNPGQANYVAANHWLEALAAARRHQ
GLPATCLRWGAIEDVGFLARHTRTRDALQERLGGSALRSEDALRILERLLLHHADRLGGP
SLGVLELEWPALARFLPTADSPRFDEIARQSEDDGRTYDDGENLAEQFANLPPEELHEAV
TDLLRVELAAILLIDEEKIDVYRSVYDMGFDSLMGVELMTAIESRIGVQVPVMVLGEASS
LDKLAGVLIHRLQSNEPAEDADDEARLADLASRHGSEELSESTEKGL
>A0A2X1TGT6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium xenopi|TrEMBL
MSALILPDGRIPVLLSAHEPDLVGRDAAAILRYVQRLEPGVPAVAATLLRLRRVRRHRAV
VRAADRAELAAALSKLADGDEHPLVATSSIAACPRIAFVCPGQGNQWPSMGADAYRQLPA
YRAEADNCAAAFVAAGHSSPLPYLLGGAEQDWAQIQIQSAQFTHCVSLAQVWRSYGILPT
VTVGHSLGEVAAAYLAGVISLSDAVAIVAARAAVVDQLPGRYGMAALGVGVDEAARLIGE
TAGWLEVSAVNGPSSTVVSGDRDAIEAVVGLAEQRGAFARAIDVDYPGHTSALAPLRDKF
SELLPAAQFLDAPVEFVSSACGKVIGAGADFNDYWCQNLCNTVRFDRAVTAASERGVDAF
VELSAHPSLLAALADLVDESAVIVGSGRRDEPIAGQLSANIAAMAVADRGYRWGDLAGVD
DLPPLSGFPNAPMKAIHLWAKREPLPPVPGSVVTVAAERWQSRRTPRPSNVRRRRIAILK
PAITDTPLPRRLADAVAAHQDCELAGVDDAEIVVAIAPALLGHDVRAAAAEITARPDMVL
PDYASAVGRSGRSVWLVTVAGEQVEPGDPVGLPAQAALAAMHRSVGFEYPDHRFAHLDLP
SPDIDADTARACVDLVLSDAVEVAVRGSRCYARTLVECRDSVSERALGTAALDNVVITGG
SGVIGRRYARHCIEHGARRLTLLSRKGLSSAQLDCLADGYAAEVHAPRCDITNRDALSAV
AAEYAGDGASLLVHAAGAASFAPHDQITSADLDQVFAARITGLASMVELWPLRPNSRVLL
CSSVSGVWGGHSHVAYAGSNRMLDVLAGQLRATGLDCTAMRWGLWRGTEIGGADEIARVE
RSGLVAMDPDAAITASLRHRGDDPIILAADFDRLRVFFETRGMPMPFTAPSQEAQPVADS
DGPEDRPVAEVVRAELAAALSLPEPASVDLGAALIDLGVDSLLALDLRKRLRRRTGRSVP
LARLLGGITGTELIDALQPGSQPKPPPAAAEVIETGKG
>Q3M9Y0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Trichormus variabilis (strain ATCC 29413 / PCC 7937)|TrEMBL
MLFYLTQRRSEKFLEAGFPGVGNFSRQRRREINEILLEFKYMTTLTQVRPASVFVVSGGA
KGITAQCVIELAQHQPCRFILLGRSEVIESEPDFARDCVEESVLKKAIMQHLVAQGEKPT
PMSVQKVYHKIVSSREIKATLEAIAATGSQVEYIDVDVTNVAELRQKLAAVGKITGIIHG
AGNLADKLIEKKTDQDFEKVYTAKVQGLENLLSCVDANQLEHLVLFSSVAGFYGNMGQSD
YAIANEILNKSAHLIKKNYPQCHVVAINWGGWDSGMVTPELKKAFAERGIDIIPVDVGTK
MLVNELHPSHHDSTQVVIGSPIIPAPGNIDPQLRSYRIRRRMTVEANPFLLDHVIAGTPV
LPATCGMSWMINACEECYPGYRYFRCQDFKILKGITFNDKVATEHILEIQEVAKHGSESI
EFQTKILSKTPEGKIHYHFSAHITIVRDLPPAPVYESLDLTEDHTIGAISKDFYQKGGLS
LFHGTSFQEITRVLNINSRKITVECCWAEIPLEVQGQFPVKWHNPYATDLSTQPLWLWLS
HVHQEVCLPGQITKSEQFRAIPRNKPFYVSCEIENKTPSGVTADIILHDREGKIYFRIYQ
AKAIIAPMNLH
>A0A0A8UQW5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Legionella hackeliae|TrEMBL
MINSAAYDYTVVELFEDQAKKTPNHIALDEDGTILTYQALNEKANQFSYWLQKNNVNPGE
FVGILLDPGIDYIVCILGIIKAKAVYLPLDSMAPQLRLEELLQDAKPSLIVTNEQYINRV
NEKSFAVRLIKHIYLESVSHPRFSNKKHFASKSPLYMMYTSGSTGRPKGVLVSHQAVVNL
VKIDNFAKVEEYERVAQFSNLAFDGSTFEIWSALLNGATLVIVPSIVRTDHTRLKSFLNH
SAIKYLFLPTGFFHQLIKSAMDTLDSVEVIIFGGEQVNALLLKDLSDYRKKKKLPIKLIN
GYGPTEATTFTCRQIINPEWSEDDERLASIGKPIKNVEVYILDENKVQVSEGELHIGGVN
LAIHYHNSPLNSEKFIPNPFCEPNHPFNRLYKTGDRVKMLPSGDIQFLGRYDDQVKIGGF
RIHLNEIENQLMQHPLISLAAVRVEIGGGSHKMLTAYIVLSATKKTIHADEIREYLSHKL
PIYMLPAKYVLVDDLPLTSVGKVDKSKLDQISHIDLSFHIDNSPASFIEEKITTIWQGLL
NRNRIDVNKNLFELGANSLLIAEACSRINEALQSELQISHIISYPTIHKLSRFLDGDIET
PVVKEIHAATSQDIAIIGMACRFPKANSLDEYWQNILDGKDCLTQFASDQLNDPNKIGDK
NFVPVRGVIGEVDKFDANFFGFNPVDASITDPQQRIFLECAWTALEHAGIAPTKLHSKTI
SVFAGMADSTYLHENLLKNNWFCKEHDRFHCRIASSSSMLSTQVSYRLNLRGKSLNVNTA
CSTGLVTVDEACHDLIAGESDISIAGAVSIVVPEEDGYTYTQGSIESPDGKCRPFDEKAN
GTVFSNGVGIVILKRLKDAIADKNTIYAVIKGRGINNDGADKLGFTAPSTSGQTACIREA
LATAKITAADVSFVEAHGTATTLGDAIEFDVLNSVYKEQTEHTHFCALGSVKGNIGHTDV
AAGMAGLIKVCLSLYHQKIPPMVNFKKANPNMALDDSPFFINTQLIEWKKPVSSKRYAGV
SAFGVGGTNAHMILGEYTAKEKLSVSTSQQLLVLSAKNLTALEENTEQLLKQLSLYSDDN
LKSCLPKIAYTLQTGREDFQWRRIATGDTLKVIRQSFSQSKAQQSPEHSPHNLVFMFPGQ
GMQYHKMATQLMKEFSLFASLVKKGFQIAKLHLHCDLETIINNPKDERLHQTQYAQPALF
IIEYALAHLLMDFGIKPQALIGHSLGEYVAAALAGVFSYEDAVALVCERGLLMSSAPKGA
MLAIECSVSEFKTIQKQITGIELAVHNAKHHCVASGKMDTIQTLENFLSQDEISFQRLKV
SHAFHSSLMETIETSFKEIFANITLSPPTMPIVSNVTGDWLTTEEAMDPDYWYRHLRDTV
LLNNGFENLIQSKHSHFIEVGPGRSLSSFLKMTVPDADAFSIQTLPNHHQQTEDVEALLA
AVGKLWQEGVTINWLALHNNKSLQRVALPTYSFQRQSYWIKPDKFRENASNQPSLYKPVW
SHQLANLEPSDIDARKIREHTWIVFQDNTEIGNQLISLLRDYNAKLFIVEPGKSYQLLDS
NHFRISLKTKSDYLKLFEHLKTELKHPILFHTTSCNPLFFGKLSNEEIDTQLNASFYSLL
FIAQAYREIMGEDTPLRCGVLTQGTQRILGTELISPVNASLIGACRVISQEHPNIVCKVI
DSNPVEFSSSKNTCLSHLLNASVNDDWLTQNILTAYRNGYQWDLSYTLAETTKIHNRFRD
KGIYLITGGLGGIGLAVSELITEEVNNPTLIFLSRTPMLPETTWNKVLAEPTHKLYPKIK
LLNHLKQKGADLYFYNVDIADSEALRETIQQCKTKFGAINGLIHCAGVAGGGLVQLKTRE
IADTVFRPKIHGTFNLLKAFKDISLDFVVLMSSIAALTGEQGQIDYCAANACLDAFALSN
AFQSKFVISLNWNTWRDVGMAIETKHPSDLNWLDRGNDISPEQGKQVFLQALRTNFTNLA
VSNFDIKSYSKLVMEKDNVSGSPDIRASRTDLNIANNYQAPRNSIESQLAQLWQESLGIE
NIGTEDNFFDLGGHSLKALKLIEKINRHFHRSLVINQLYQTPTIAELSDVISSSTGNLKM
MDIIVPFNYTVNTPNLFVCHPISGLVYCFDSLTKCFNTPLSIYGLQDPSVGNDHLLYEDI
SSMAKAYLDAIKSIQPHGPYYLLGYSFGGSLLYEVAALLKKQKNQINLLGLIDSWASFSP
KQSNETHFKKLLRISHPDLPENMIELAWKRMQLLLSHTPTKLNQDMLLFKASDLAEDYQS
INDPSNGWSNFNKGKITCHMLDANHETILDAENSKYIVNYIQEYCGL
>K2DE52|6-deoxyerythronolide-B synthase|EC 2.3.1.94|uncultured bacterium|TrEMBL
MKPLTESKDIAVIGMAGRFPGAKNIQEFWENIENKIESIISFDKKELFNSGIPKDLLDDS
NYIKSKGFLKNASMFDAKFFNINAH
>D9UBR5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces pristinaespiralis|TrEMBL
MDTLLDAPRDVVLLLPGQGAQYPRMAAGLYDSDPAFTDAVDRCLALFPDGELLRDDWLAE
QPAIGIDDVRRAQPLLFTLDYALGRMVLSWGVRPAALLGHSVGELAAATLAGVFTLEDAV
AVMHDRVTRIAPTEPGGMLTVAGTPDDLRPFLARHPHIAIGARNAPRQTVLAGLSAPLRA
IAADLRGAGITTLPVAAHHPFHSPVLAPLFRDLTLYRRITAHPPLFPLWSAFTRTRLEAD
TVADPALWAGHPVAPVHFWPTLDKLLSTGRHLLLETGPGKGLTTIACRHRSVKLGRHTAA
ALLPARPRTPDDDRLHTDRARELLHTTTALAPQPA
>F4C2F5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Sphingobacterium sp. (strain 21)|TrEMBL
MNKKDIAIIGMSAVFPGAPDINSYWNNILKKVDATGPIPPSRINERYFIPDDESYDRFYC
SRGGFIDDYAHFDPVTFGILPLAVEGMEPDQLLTLQLVHSALEDAGVWKNKYKLDRTSII
IGKGNYVGPGATRAVEVVHAAEQLVNVIRHLMPDLKEEEIKRIKKEFQKKKGRFTPDTAM
GLIPNLIASLVANRFNLGGAAYTVDAACASSLLAIDHAVNELVNDRSDMVIAGGVHVGQN
ATFWSIFHQLGALSKRQQSRPFDKDADGLIIGEGCGFVVLKTLDKALLDGDRIYCVIKGV
GISSDGSGTSVMSPSTKGQARAIEQAWQQAGLSVNDIGYLEAHGTATVIGDRTELETLKL
VFGSASKGNKAKIGSVKSMIGHAMPAAGIAGVIKTALALYNDTLPPTLHCDSPIEVLAET
RFEPVNEPINWSSSGLPLRAGVNAFGFGGINAHVVLEAFTVKNTVHQAKRVAEDEVRVLA
RKSVDELILALESDSNDIGDGDFRIAVFNPTVDRIKKAINIVTKNKPWRNRQDIWYTNAP
LLRGEKKIAFLFPGLDGLSSGETESVSKYFKIEQEFLLEDSMHETKVFVSALNQLQNSRT
IDLAMKKLGVVPDINAGHSMGEWLAAMSAGLVTTSSVKHLITKLDPQLFEVSYARFIAVG
CSYERIKGISEKIPSLYLTNDNCPQQVILCGTHEAIEQLITELKVHQIFHQVLPFQSGFH
SPFIKDRVPQILEGIEEIDFLRVKIPVWSATNLAPYPDTVEAIRQLNVEHLIQPVRFREL
IEKLYHQEQVRVFIQIGAGGITGFVDDTLKGNPYNALSATSPYRDGLSQLRRILASLYVD
GKEVDLDFLGLQTKSQKAASVKLNLGSPLVSTWDFPVHSSFTKPPKDTGYVRTQRTVKHP
LAMAVMDNMEEAMGMYSDLIELIENKEFLNPLPQRFNRFGTESHVPGHFETPFNISLDQH
PYLIDHALVKQKPGWHCPEDMDPVIPMTMILELLGEAAFNHERQRKLSRIQQIRVFQWMN
VSKPFREKVVGERKNDSIWSVRIDKYAEAEVVLAEKLESSSLQLLTVGNLLDIQIDPVTI
YDRHMFHGPAYQGIKAVNSIGDKGIRGIIVGSGGKGSLLDNAGQLFGLWLQLTLKVNKVA
FPIKIDEIIFYQDFADQTGEFECTCSLTDINDETATANFLLKRDGKVWAVINGWQNIRLE
FDERLWQVSMSPKFNLLSEEIYPEVFKFHKAYQKVISWDFIAKRYLPLADRNFLNGLALN
KRKKWLVSRVALRDAIRSLLLRETNTAYYPIEFSIAKLATGQPVIQGPLAADVQISIAHK
NDEAVAIARLGKPVGIDMEEIKSRGVGFEEIALTANERLLLKGKEDRDEWITRFWVAKEA
YGKSIGKGLAGNPKTYQVGAIEGDELIIESIKVKTIKYNNYIIGWTL
>A0A498QFC6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium innocens|TrEMBL
MMVTHRLPDNRVPVLLSAHEEELIGQDAAAILDYLGHLWAQPGTDDVTLAVAATLLRTRR
VRRHRAVVRAADRAELEAGLRALAAGEQHPLVARSSENAKTRTAFAFPGQGNQWPSMGAE
AYQHLPAYRAEADRCAQAFVAAGLPSPLPYLLGPVPAGLAAGWRAGSSADTDHGWSQIDI
QGAQFTHAASLAQLWRSCGVLPDLTIGHSLGEAAAAYVAGTITLADAVAVVAARATVVSR
LSGRYGMAVLSRGADQAEQLITETPGWLELSAVNSPSSSVVSGDRDAVAAIVRRAEKDGI
FARELTVDYPGHTSKLESLRDALSELLPASKFLDAPVEFVSSAHGDVVTPDTDFTDYWYQ
NLRNTVRFDQAAATAGQRGAGTFVEISAHPSLRYALAELAEDALIVGSGRRDEPVVEHLS
ANIAAAAVANPGYRWRDVAGVGDQPLLRGFPTAPMRAIHLWATPEPLPPPPGSALVVAYE
QWEQLRPHDRSQHNAADRQPTAVTIATPDSADDPLARRLTQAVGAHPACDLAATAEAEIA
VIIAPALMQPDAIVAAGQLRSGARQLDYHHAVGPRCRRVWLVTICGEQVDAAAPAALPAQ
AALAAMHRSVGFEFPEQTFAHLDVPSREIDEATAHQCIDMLLDDHTEVAVRARDSGTGLD
WFVRTLREAAESAPEGVDAAALDHVVITGGNGTIGLRYARHCVEHGARRVTLLSRNGVDR
AELDRLTAGYPAQVHAPACDITDADALAAVAGEYAGDGASLLIHAAGAARFAPHDLLGDQ
EWADVFSAKVTGLVRMTDAWPLRPDARILLCSSVSGVWGGYGHAGYAASNRMLDTVAAQL
RGNGLNCMSVRWGLWQGTTIAGADDVARIERSGLIAMDPDAAVATSLGCRQADPLILAAD
FDRLRAFFESQGVAKPFATATTERNDDSPADSQSSDQRPISELVRAEIAAAFSLDGPAAV
DLNVALVDLGADSMLALDLRDRLRRWTGQSVPAARLLGGITGAELIAILQSAPSADGPAA
SPEPMAPEPTAEPGSTANPERRERLRSSRD
>D2AZU2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptosporangium roseum (strain ATCC 12428 / DSM 43021 / JCM 3005 / NI 9100)|TrEMBL
MSLNQETTSASEPIAVVGMACRLPGARSPEELWELLCRGENTISEIPSDRFPVEEVYHPA
SGVPGKLASKYGGFVSGIDEFDAAFFGISPREAATMDPQHRMVMEVAWEAFDDAGLVLEE
MPQRTGAVFMGVITSDYWDRQSGAAEELDVHTVTGSTRGGNAGRISHALNLKGMSVALDA
ACSSSLVAVQLAVQSLRAGSCDLAIAGGVNAILTPDHAIGFSQGSMMALDGQCKAFDARA
NGYVRSEGAGIVVLKTLSRALADGDRVHALIRGAAASNDGHSDSFMTPQIPGQQAALTAA
YRDAGVDPASVAYVEAHGTGTSAGDPVEIAALDSVLGRGRPEGRPLLVGSAKTNLGHTEG
AAGITGLIKALLCVQRGWLPASLNFTTPNPSIPWDSIGVRVCDKGQPWPDLDGPRRAGVS
SFGITGTNAHIVVEEPPSASRPDEWSRQEERREDGDRAVLLPISARTPSALGALAARYRD
LLASSLHQIAGAAGTRRSHHDQRLAVVAGTSEEAAAKLDAFAADGHAEGVYAGEADDVRD
PGAPHLTAWVFPGQGAQWVGMGRDLLDEEPVFATAIADCENAMRRYVDWSLTAELNAAPE
TSRLAEIDVAQPTIFAVQVALARLWRSWGFEPDAVIGHSMGEVAAAHVSGVLDLDDAARI
ICGRSRLIRATSGQGAMAAVELSSERVQALIAERGGAAVLAVSNSPTSCVLAGGPEEIDA
ILRDLDAEGVFGRRVQVDIASHSPQMDPLREPLLELLAPLRPRRGDVPLCSTVTGRFLDG
AGMDAAYWVDNLREPVLFADAVQHLVEEGFDTFMEFSPNPLLARAVQQNLRHVGRDGAVV
TALARDTPGRTSLLEAAAELYVKGRAIDFSRMQPHSGQHVPLPSYPWQHERYWKDPVRRA
ATVRDGGGHPITGTALTLAPAGTLVWDFDLDVERLPYLNHHRVHEMPMLSGTGYHELALA
AGEEAYGDRSFAVEELHLERAVFLTPGTPQRLQARLDPDEAERGRRWTCYLADVSTGGTT
EWTRVATALVRHCSPTAGDRHIDLPDVAGYRETVDVAEHYSELRRRGIKQTGPYQSIVAL
HRTDAAVAAELRIDDAITTGLQRYLCHPALLDAALQPVMAVLGNGDTGDDTYLPVRTRRC
RVHARPQPGARLWSTAVRTSTAQEPDLVEFDVLVSDDEGRVLASIDGFQIQRLVADPPEV
VERKAGRLLYGVEWAELEPLTDPVPERAPWLVVSDSPLGAELCASLAAAGGEPLLVQPGA
GYRRLGPHRCVLDLASTEDWTMLIKEQSESGAWPPRAVVRLSTAPPVEEATRPDALERSY
EVLALVKGLTSDQQAAPRLWLVTTAAQTPDGSSDVNPAETAVWGIGRVIPYEHPELRCSM
IDLPEDPDSGILRALSAEIRTDGIETEIALRDGRRYTARLRHRPLPSASPVPVRPDGTYL
ITGGCGGVGLLTAEWLVKNGARHLVLVGRGGAPEGVTDRIAAMRSAGAQVLIARTDIASR
VAVADLLDDIARHMPSLRGVVNSAVVLDDGTLAQLDRARFLAPMPPKVHGSWHLHELTRH
LPLDFFLLYSSAASVIGSPGQGNYSAANGYQDGLAWHRRANGLPALTVNWGQWSATGQVA
KASKDLRLNERGFAGFAPAEGLAVLDRLLPSLHAQASVMSFDPTAWTHYFPALRTSSLLR
HLVEGGPGDAAPAAELEPADLAGLGNEQAEQLIAAYLCTQVAAIVQLPRAKVDAAQRPHR
MGLDSLMAVQLRNRIAADLGVTLPVAVFLQRRTIGDLATVTLTHLKEPEAVPSGSDRSTA
GGPAVTNSGDGRNDSGRGLQLI
>V4ZD50|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii (strain ATCC 50861 / VEG)|TrEMBL
MVWLFTGQGSQYVNMAKSLYETEESFRQTVKECSAYLATEKLLPTEGPSSLEDIIYPGQD
ADAEEAEHLLMQTQYSQVAIFVVELALTRVLKERGLRPAAVLGHSLGEYAAAVTAGVFSW
RDALRVVAVRARIMSEQDPQDGVMAACRLSAAEVQAALDSDLKNLKSVAVAADNGPRSVV
VSGRRSEVEEVLSFFSISGRARFLRVSHAFHSPLMAGAVEPVSRLFERVEFSKPAIPFIS
TVLGRLAVGSELSDALYWSEQITKPVRFREAIHAATSGEFSAMQAYIEVGPSRVLAAMGR
DCDSGADGTIHEWLCTVDPRSAANPFEAIATLQERFAQRLPMDESVRHTWNHSAFPWTVP
RHPLIGKEMPTVSAAGGEQVSRYSSRVRLDVLDALRDHVILGMPLMPGAAFIDALLAAGR
LEHTRIDRRISSSAVIKLSDVSIFSPLLLPESLGSGVAPGEQGFHPSSLELSVEMKPDGR
DHLAEVRSRRIGTTLAAANEEEYEQSHCRGRLAISAGTSQLPASTGGQLTDLQRRFYSEA
AVDVSQLYATFAELGWQYGKLFRPIAQLFKTDTEAFAELRLPRPVLPCEEGFIIHPAILD
GLFQVAGSLLLTAEKAPAGSVYVPIGVDELAFIPSTSKRDIVWGRVTFAEADDEAKRRQE
RVVNCTLYDEGGRVLLYVSGLRSRLLRTEVLLSGTGAAAESNKLWSVEWRASHQQPVAHH
EEPVDHSTNWLIAGVHPAVQSQLEEFFLKTMPGAKVVFCAPSVVATDVRRLLQQEAWNGI
IHIGGVTASISEMECLSDVLVLLQAVIDWQANESSPRPLPAMFLVTRGACCEATENSGLS
HSLAPVHSGMRGLFRTAKAELEALWNRFVPLHYINIEPSSDKQTVTPEELRQVFSVIQQQ
GAKAQFIQDQLTQEPSKPLFYESESLLRDGELLLPRLVPASLEDCGDGNALAEAMTGTIV
ITGGLGGIGLVLAKWLTGQEARAVVLVSRTGTPSAEVQRSEDWHLLQSRRQHQTRIVTAS
CDVGDREQVKLLFRSLRAGSFVCHSTGQVVELPPIRGIFHAAGVLRDCPIQKQDAETLAS
VFRPKSQGAWNIHNALEELNMNEGLKVFLMFSSIASLVGNPGQANYAAANSSLDALASYR
RCRGLAGHSIQWGPWIEQGMAAELGERLERAGFRGISNKVGVEVTEAVVSQGTTGDFVVA
CQEFIWPRFVMRYRGCLPAIFEEQTRSVTVRMRDERSSRQAAGPEMHQESAFASMAPDEL
RALIQATVSGAAKQVLGTAEEPPADAPLQALGIDSLGAVEFRNAVQDAFDIRLSATLLFD
YPSVQAVSDHLWSMVRAKTAIDTSSRGDDQLASAAVLQDTGVSIAVVGMACRLPGSVNDL
EAFEEMLLTFQDCIQEIPPSRFSIEEVYDPDPDAKGKIYVREGGFIDGAELFDNRFFGIS
DAEAREMDPRQRISLEVSYEALVDAGYSREDLLGSPIGVFVGAMNHDKLYDDLRQLTSYS
GTSTALAILANRLSFTFGLTGPSLMIDSACSSSLVAVDYANMDLRQGRSEVALVAGVNIM
PTTDPYVHCCKARMLSPDCRCKTFAANANGYVRSEGCAALLLERTATPKRRNITPYGRLL
GTANNHVGRSASITSPNGPAQQA
>A0A4R8QZM4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides franklinii|TrEMBL
MTTLVQFPGLGGYAPGMLAQLTQDAPRVAGILEEVDRVAADYGLGTVSGPLTDPNGASIE
KLADTPTLLHLASYVSGYVMYQAMCARGTGGDMLLGHSTGEITALVAAGALSVADGARVL
CEREVALAELDVSGGLVALAAGSARAHHLCGAAGGLSLTVSLSNSPVQTVISGTDQELPR
LEAVARAAGVQATRLLVRYPHHNQILRRAADLVAEAAVTYEIADPKSRVYSPILGRFVDH
AGDARRIIDRHLTDPVNYLHAIRTLYDDCEVRTFIEVGVRSVLTDSARESLPASVTLLGP
PPVARSAVEILDILSGVTAPVSLRDLQVVKPPADTAGATNGSAPAVMPVNGSGAASLPSR
EALMARLRSLFAASLGYPEDVFTDDAHLEADLGIASVKKTELLVRLLDEFQLPTPPAAMR
MRDYNTIPDLARLMENLGTNGASV
>I9NJT0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pelosinus fermentans JBW45|TrEMBL
MNQPKNYEPIAIIGMGCRLPGGANDPEEFWEILKNGIDCISEIPSNRWKASTFYSANKEI
PGKLLSKWGGYIDGVDEFDPTFFGITPREAEYMDPQQRKLLEVTWEALEDGGQKPGELAG
KPVGVFIGAFTSDWKILQWGGKRHDNLAAHSATGAMMTMVSNRISYIFDFTGPSISLDTA
CSSSLVATHLACESLRSKESSMAVAGGTLLQFAPQYTIAESKGGFLSPTGWSHAFDSSAN
GYTRAEGVGVVILKRLSDAIKDGDPIYATIIGDGANQDGHTNGITVPNGKAQEELIKTVC
AKAGIQPGELQYVEAHGTGTPVGDPIEANAIGAVLGIGRKSGEKCFVGSVKTNIGHTESA
AGVAALMKVALSLKNNQIPPHLHLKEINPKIEIDKWPYQIPTKLESWPEHEGAAKAGINS
FGFGGTNSHVILQEPPLSTTFDKTILEVKRPNILPLSTRDSEILPDIAQKYKELLEKANE
SCPALKDVGYTASIKREQHDHRMAVLYSSKEDLLQQLNMCIAGEESPSIVKGKKWEKNKR
NLVWVFTGMGPQWWAMGRELFEKEPVFREVIVKCDREMSKWVDWSLIHELINVSEKESHM
EETWISQTANFAVQIALAALWRSLGITPDAIVGHSTGEAAAFYEAGVYTLEDAVKVIVNR
SRLQHTVSGTGKMVAVGLSASEAGPLLAPYGDKISIAAVNSPNSVAIAGDEAALREFIKP
LQQQGIFCKFLQVQIPFHSAYMEPIKEELLRSLHDIKPQKTKVALYSTAMGAVVEGTELD
AAYWWQNVRGTVLFTKAIDQILDDGYRVFLEIGPHPVLAGSISEVMVDKKQDGKILCSLR
RKEKEQERVFTSLAELYVMGFPVNWQTLYPNGKFTRLPTYPWRKDRYWTEPRDIEQARLG
QKDHPLLGFRLFAPEPSWEESISAEKITYLKDHQIQGSVVFPAAGYIEMAFSALSSLLGA
GTFSLEGFEFKKALFLPESQEPKAQFLLDKEQSTFKIVTYEDENNTAVSHAYGKAHVIQN
TQIAPKIDIDGLKTKLANYMSDKECYEKLGAMGYHYGYSFQGIKDLWIGANEVLTKIQMK
EEVLADAAGYFFHPTLTDACFQTLITAEFSKSSSAEQMAIRLPVFIEKIRLTQGHTGPIW
AYARITDSDVHKLVGDIYLYDEDGNAIGEIKGFFAQGVDQASGNASLSTIDNWLYDVQWQ
EQERSIVGEKTENISGKDNSGWLIFADKQGVAEELLGLLKQKGEYCCLVYPGDGITINNS
NSLATVASDTDGEVSSLIKTIFKDKNRKCKGIVHLWNLEAPSLESMELADIEKIKKLGCY
SILQIARAIGDLEIPAKLWIVTRRAQVVGEDTGDICAAASPVWGVGRVLGQQELVGNWGG
LIDLDSVASPERLKQDALNVFNEMISGDKEDLIAFRGEKRYVPRLHYASNLTKPLPTRFR
SDGCYFITGAFGALGQLVARTMVKHGARRLILMGRTKIPSRGEWNTVQPGTGNAEKIAFI
KELESLGADVLLASVDITNELQVAEYFKQFKEMGYPPIRGIIHSAGTVNDKFVSKMDAKT
FDSVYDPKVYGSFLLHKYLKDEPIEHFVLFSSVADLVTTAGQTNYAAGNAFLDALAHHRR
ANGLPALSINWGPWATGMVKELDLIEHYRLRRGMNCILPEVGMNILDRVIGQDVSQIMVC
EVDWPLALPWYPSEPPLFAHLAKKEDNKNDGDNVSFEILFKNADEAFRKVIVEEQLTELI
AKVLRCKPSQVEPNSSLNALGIDSIMATELRNKIAFHFGHSLTIVKLLSGSTIMQLAEAL
LEGLSESIGEAENEAAAAVTAEVADAWGLLDSLDQAGIGEEGKVVDEYPLSYGQKAIWFI
NQLLPDSPAYNIGGSLHIPVKIDIEALRKAVREVIQRHPGLRTNFFIKGGEPYQRVYASR
KEEIEVVDVPGMEWSDIRKMVIADNRKPFNLEKGSLFRITLYKQSEQDYYFAISIYHVVS
DAWSNYMFINEMQELYEKYALGKMVELPPPTATYKDFVEWENRFVNSSKGIKMFNYWRNH
LPEEMPILNLPTDKPRPVVLTSNGASYVFTINKELTQSIKDVSKLTGATVYMNLLSAFYI
LLHKYSTQNDVIIGSPVAGRTNPDLSKVYGYFVNPLPLCASFEGDPTFKELLKQVQGSVF
AGLENQEYPFALLVDRLSLEHDPSRSAIFQVMFVYLVHRLEQVGVDGNSIAADVALPVHY
LAIPEEEGQFDITMSIYEENGEFHGAFKYNTDLFYEATIARMAGHYNALLEEIIEDPEAK
VSKYNVLTKEERATILGHWSGGKGAFATDSSIHALMEKAASQKPNSIALSVPYEDGRTDY
LSYDELHRKANQFARYLQKVGVKPNTVVGVCLDKSTELAVSLLAILKAGGAFVSLDPNYP
KDRLTYIMDDSAAQVIISHSSLKEALDCGTRRTICVDTEQANIEGEEENNLDNISKPSDL
AYVVYTSGSTGQPKGVMVTHQSFVSVYKDWETEFHLLEKTSSHLQMASFSFDVCYGDFAR
ALCSGGKLVLCRREIMLNIPLLYEIMVAEKVDCAEFVPSIIRNLIKFMKSAGKKLDFMNL
VIVGSDTWTVDEFSWLKSYCGENTRVISSYGLSEATIDSTYFEGDVEFFESGSTVPIGKP
LPNTQVFILDPFMNPVPVGIPGELYIGGAGLALGYINKPELTEERFILHSINGQSPIRLY
KTGDMAKWDVSGNIHILQRVDNQIKIRGYRVELGEIEKHLTNCPGISKGVAAVKNDKNGD
KVICAYYIPSVSEVDKKLIRGMLSEVLPSYMIPSYFIQVTQFPLSHNGKVDINALPLPNY
TEESEVVSEPQTIYELRVAQVWKKILGVRKVGLQHDFFNLGGNSLYLVELMIHLQNEFKI
KINVSQLFKASSLGDMARVVENIVTGKEKGAEPYIEYNPSRKRVVYSFPPAGGYSLVYSS
MADSMNDVTFVSFNYMMEQDKIKRYADMIQSYEKEGPYILLGYSLGGNLAFEVCKELENR
GKEVSNVIIMDSYRIDGTFAPTDEDMKKFEVELAEHFKRHVGSAVVQEHTLDQAKDFINF
CYETMNKGTVKSKVHFIIEENSSDPHRTKRESSWDGSSQTSATLYQGVGKHEEMLDKTLV
RENANIVRTILEAL
>A0A0C5QBV3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pelosinus fermentans JBW45|TrEMBL
MDINVDNIKMGIKEILMDLLKCSNDFLDAEKSFLEIGINSIQSVELVESINQKLGLKLGI
DAVFDYTNINELAGYIFDQFRIGHCDKRISMVGDTEEGFRENNLNCMENAECLLEDFPTM
DKLRVIEPEQYQVSHDPKAVPEKKESSISVGERGSDIAIIGISGRFAGAENVEEFWNHLQ
AGDNCIEEINRKGWDESKYYSPDPGQVDRAVSKWGGLLNNIEEFDALFFNISPLEAERMD
PQQRLFLQEAYRVFEDAGYSAEELSGRKVGVFVGGRTSDYKEKTLLTQERNSQTFLGNDM
SILAARISYFLNLKGPNIAIDTACSSSLVAIHLACESIHSGRSEMALAGGVFVLSSPEFY
VMASKTEMLSPDGQCKTFDNRANGIALGEGVGVLLMKKLEQAVADGDYIYGVIKGSSINQ
DGRTKGITAPSMLSQKALLYDAYKNAAIHPETVSFIETHGTGTKLGDPIEVKALTEAFQM
FTNKSQFCAIGSHKPNFGHAIISAGIAGVLKVLMAMKYRKLPPQINITEVNEHIDLNKSP
FFINRELREWKSRDGGPLRAGVSAFGFSGTNCHAIIEEAPIRKRTSGNAKPCYLFPLSAK
TKDALERKIADMIHWFEEKVQNERADEISYTLLAGRSHFSARCIFIAEDLYELQQQLIAV
AKSGLAEFSFREEVKGLKDYGEQLMAELREDRSINAETYKEKLSVLSELYISGYTLNWAN
LFDRSRRVPLPTYPFAREHYWIPDVTSTDHSRVEGAGAFMPIHPLVQRNTSDLSEQRFSS
TFTGQEFFLKDHVVKGKKVLPGAAYIEMARAAVEEAAGGGNEEKTRVRLTNMVWMRPILV
DTQAAKIHIGLYPEPTGEITYEIYDEAEVYSKGNAVLISGTEAPDLDIEAWKTRCNRSLF
SSGQCYETFKEMGMEYGPGHRGIDTVYLGENQVLAKLSLPSTVSHTRDQYIVHPSLLDSA
LQASSYLLMEQGEGTKTMLPFALQEVEVIDHCTPAMWALIRYHTGSANKDKIKKIDIDLC
NETGKICIKIKGFSTRVLEEKAGAFETAAKKSVLLFHPCWKEKASTPSIPPLYEQRLVIL
CEPDQKIQESIEGSQPEIQHLVLQCQVKGIEERFQAYAIQIFEQIQIMMKNKRKENILIQ
IVVVKKNEGQLFSGLSGLLKTAQLENPKLRGQIIEVDREEETGEVVKKVEKNSYSLDFQI
RYQNGKRYVMEWKEIEDSQEKSSIPWKDQGVYLITGGIGGLGRIFTREIISKAKDTTIIL
TGRSPLNEEKRGTLKELEAKGGKIEYKQVDVTDKKGIAHLIQSITKEYGNLHGIIHGAGI
IQDNFIFKKSKEEMQKVISPKVSGLVNLDEASKGLPLDFFIFFSSIAGSLGNAGQSDYSV
ANAFMDSYANYRNELVGLKERYGRTLSVNWPLWKEGGMHVDEEVAKRMLQKMGMLPLETA
AGIQALYRGLSSGVEQVMVLEGERQHLHFENIGQPVKVSIEGSNFLEKSEEIAGISSNVL
REKTIRYIKMILSSVLKLSMYQMEENTPFEKYGIDSILVLQLTDRLEKDFGSLPKTLFFE
YQTIQELSEYFLETYYSQLVKIIGYGENTATSKDLEEVEPIFESKPGEIRQRHSRFISVH
SNSQKEKSIGTLDIAVIGVAGRYPGAKNLHDFWEILRNGKDCITEIPGDRWDHSLYYTND
KTKSGKTYSKWGGFLEGVDQFDPLFFNISPREAEFIDPQERLFLECVFETLEDAGYTRNT
LTTDFGGNVGVYAGVMYEEYPLYGAQETIQGRPVALWGSPSSIANRVSYFCNFNGPSMAV
DTMCSSSLTAIHLACQSLQRGECKLAIAGGVNVSIHPNKYLFLAQGNFISSKGRCESFGE
GGDGYVPGEGVGTVLLKPLAKAIADGDQIYGVIKATAINHGGKTNGYTVPNPHAQAGVIG
KAIEDAGISPRAISYLEAHGTGTFLGDPIEIAGLTTVFRKNTKDKQFCAIGSVKSNIGHC
ESAAGISGITKVLLQLKYHQLVPSLHSKRLNSNIDFKNTPFVVQQTLEDWKRPIVEINGE
KIEYPRIAGVSSFGAGGSNAHVVIEEYAAKELVPRHTTSYSFPMIIVLSAKNEERLKEQV
QQLLNAIEKEPFSDDNLADIAYTLQVGREAMEERLAVIAGSIHELERKLKDFLKGRADIA
ELYRGQGKRNKEVVSIFATDEDTAVMLDTWIKKEKYDKVLELWVKGVSLDWNRFYRDFKP
HRISLPTYPFARSRYWIPDVTSTDHSRVEGAGAFIPIHPLVQRNTSDLSEQRFSSTFTGQ
EFFLKDHVVKGKKVLPGAAYIEMARAAVEEAAGGGNEEKTRVRLTNMVWMRPILVDTQAA
KIHIGLYPEPTGEITYEIYDEAEVYSKGNAVLISGTEAPDLDIEAWKTRCNRSLFSSGQC
YETFKEMGMEYGPGHRGIDTVYLGENQVLAKLSLPSTVSHTRDQYIVHPSLLDSALQASS
YLLMEQGEGTKTMLPFALQEVEVIDHCTPAMWALIRYHTGSANKDKIKKIDIDLCNETGK
ICIKIKGFSTRVLEEKAGAFETAAKKSVLLFHPCWKEKASTPSIPPLYEQRLVILCEPDQ
KIQESIEGSQPEIQHLVLQCQVKGIEERFQAYAIQIFEQIQIMMKNKRKENILIQIVVVK
KNEGQLFSGLSGLLKTAQLENPKLRGQIIEVDREEETGEVVKKVEKNSYSLDFQIRYQNG
KRYVMEWKEIEDPQENSSIPWKDQGVYLITGGIGGLGRIFTREIISKAKDTTIILTGRSP
LNEEKRGTLKELEAKGGKIEYKQVDVTDKKGIAHLIQSITKEYGNLHGIIHGAGIIQDNF
IFKKSKEEMQKVISPKVSGLVNLDEASKGLPLDFFIFFSSIAGSLGNAGQSDYSVANAFM
DSYANYRNELVGLKERYGRTLSVNWPLWKEGGMHVDEEVAKRMLQKMGILPLETAAGIQA
LYRGLASGAEQVMVLEGECQHLREFFTGFSPTKEATPSVTQEYKIGFTIEEDLFQEKISD
YFRKIIASTIKVPMKEIDAEDPMDEYGIDSIIAMQITSNLEEIFGSLPKTLFFEYQNIKE
LTAYFFEFHSKQLLDLLGIREEETTVLREFEPIIESVKSHEGSNCSRPRFIASREESRGK
EEKNNGDIAIIGVSGRYPGAKNIGELWTNLQAGRDCITEVPKERWDYHTYYDEDKNKSGK
TYCKWGGFLENSDRFDSLFFAISPEEAKFMNPQDRLFMEIVWNLFESAGYTRESLKHQYQ
TRVGVYVGSMYQDYDSKSSSINELSTFMCSSIANRISQYFNLQGPSVVIDSMSSSSAIAI
HMACESLIRGECRLAIAGGVNLLYLQKYLRLSKIKMIGSHIHSRSFGDGDGYLPAEGVGA
VLLKSLTQAIKDGDRILAVIKSSVTNHGGHTNGAATPNINAQIQLIEDNFKKTGMDPRTI
SYVEAAANGFPVGDLIEISALDKAFHKFTNDQQFCAIGSIKANIGHAEAASGVSQLTKVI
LQLQHQQLVPAIGTETLNPNIHFEKTPFYIQRKLTEWKRPMVWIDGEEREVPRRATVSSF
GAGGSNVHLIVEEYIPSQNETIHVRSQISPQVVVLSAKNQERLLVACQQMLAFIECREEL
FLQDIAYTLQVGREAMESRVAMVVNNREELIQGLKEYLKHPKERACVPIFAGNLEEEHEM
KNLFSGNTGEKFSQVLLAEKNLKKIAMYWSQGGKIPWDSFHEQNEVRKIFLPSYPFEECH
VVSI
>A0A0J6WPF5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium chlorophenolicum|TrEMBL
MPFSELPDGRLPVLLTAHEADLLPDAARDVLDYLGREPGEVAQIAAHLLGTRRLRRHRIV
LRARDTAELADGLRAVVAGRDHPLVARSTGSATSRRAFVFPGQGTQWPGMGAEAYRGLRV
YRETADRIDAAFRSAGLTSPLRFLTNPPAGESVSHLELQGAQFVHAVALAAVWRSCGILP
DLTIGHSLGEVAAAHVAECLSLDDAIAVLAARAAAIEAIPGDHGVAVLGMDAVEAAELIT
RAPGWLELSAINASTSVAVSGERRAVTALVDAVAGTGRFARPLAMSFPAHTSAMDACGRG
VTDALPAGEFTESAVPFIGSATGDVVAAGTDLRSYWLANLRNTIRFDRAVDTGIAHHADA
FLEMSGHPSLLFAVEDGVDRSVPPRQALVLGSGHRDQPIADSLAANIAAAAVADPGFRWA
DLLATRPHRLRRFPGAPMRAEHLWAVSASPPAQPTLTVTGERWEPCVVRGNVVPAPRSVA
VLGAGPGRRPDPAWAEAIRRHRAAVPTAASEAEVLVVLAPSFPDADAAASVGALSTALDR
GLLDYADAIGARCRDVWLVTDGAEQINPDDAAPHLASAALAAMHRSVAHEHPDQGFHHLD
LASSDRAAAADILDILLGTTGEIALRERVCYRRTLDREAPPAHRFDAGVLDDVVITGGHG
TIGSAYARALPALGARRITLLSRRGERDDFAGAHGTEIVSRACDITDPAAVAAAARTAGE
ATLVVHAAGTAAFAERTGITGAALTEMAAARLAGLDHLTATWPMTADTRILLCSSVTAVW
GGRGAAAYAAANRMLDVAAARLRSAGRHAVAIRWGLWEGSTIVDATETARVQRTGLRPLT
PADAVAASLADHPIDPLIFAADPRRMQSFLAAADQEPPPPVADGPVTASEAVRSQLALVL
NVDAATLDLEESLFDLGVDSLLALDLRRRLTRTTGHTVALASLLGGITGTDLIAALQRER
ESPA
>D3D725|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. EUN1f|TrEMBL
MAHDDSPAPAALPASTPAPASTPAPASTPTPTPTPAPAPAPAPASRTALTRALDTIRSLR
AQLDAQRADQPLAVVGVGLRLPGGIDDLDGYWTALAAGRDLVTPLSQTRMGPFADQWAGL
HRKGGFLDEVMDFDAGFFGIGGREARRLDPQHRLLLEVAWEALEDAALPPERLTETRTGF
FVGITNQDYDDWRPADVDAVWGIGNAICYSAGRVAFTLGLTGPAMAVDTSCSSSLVAVHL
ARQALLRGECEVALAAGVNLIVSPASTRLISQSGLLAPDGLCKPFDARANGFTRSEGCGI
VVLKRLADARRDNDRIHAVIAGSALNQDGRSASITAPNVRSQIDVIAAALADAGLTAADI
GHLEAHGTGTALGDPIEMDAIATVLGRPRGGRRLTVGSVKSNLGHLESAAGMAGLLKAIL
CVQRRAVPPLVHFRTLNPRLDLAGTGIAIPTEVEAWSPDDGRYAGVSSFGMSGTNAHVIV
GPADVGAVVGAGVVVGAGAGEGAAAGGAEGAA
>D3D7E5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. EUN1f|TrEMBL
MAGQHRSTWWETLLALPEVEQHRVLLDLLRRNLVRAVGDEGERVPFDPRVPFTRLGLGGG
STAGFRDALSTELGLPLPATLLFDHPSPERLASYLRDRVLRTSVSAGVAGGSSPGGEARP
DPVHDPIVIVSMACRFPGGVRGPEDLWELLVEGRDAVVDLPTDRGWDLAAGYDPDPSRSG
TFYTSQGGFLDDVAGFDAAFFGIAPREALAMDPQQRLLLEVSWEALERAGIDPFSLRGSS
TGVFTGIAVADYSPPWRTAPAAVEGHLMSGTLPSVASGRVAYTLGLEGPAVTVDTACSSS
LTALHLAAQALRAGECTLAMVGGATVMSTTDVLVEFSRQQGLAPDGRCKSFAQAADGTGW
AEGAAVVVLERQSDARRNGHAVLAVVRGSAVNSDGASNGLTAPSGPAQQRVIRAALAGAA
LTPSDVDAVEAHGTGTRLGDPIEAQAIIATYGQDRAADRPLWLGSLKSNIGHTVAAAGLG
GVIKMVLALRHGLLPRTLHVDAPASRVDWSAGQVRLLTEPVPWPRAARVRRAGVSAFGVS
GTNAHVIVEEAPHVADVSATDVSVADDSLAGVSVAGVSAAGDGGPGRHLPWLLSARSEPA
LREQAARLLARVTSEPRPALVDVAWSLVTGRAVLEHRAAVVAADLAGMLRGLGALAAGEP
SASLIRGVTRPARHTDRLAFLFTGQGAQRLGMGRELYGRHRVFAESFDAICSAFGQHLTR
PLRDVVFGTDPVPTDAPTDAALDRTEYTQPALFALEVALVDLLGSWGVHPDLLLGHSIGE
LAAAHVAGVFSLDDACALVAARGRLMQAMPAGGAMVSLRASEAQALDLLAAWGGPTGPGA
GQVDVAAVNGPESVVLSGDARAVLEIAQRWRADGGKASRLHVSHAFHSAHMDGMLAEFGA
LVRGLSMRPPEIPLVSNLTGQIADPDELRSADYWVRQVRSAVRFRDGIDRLHERGVRTFL
EIGPDAVLTGMGQECLAGETDAVFVPTLRRDADEHTALDRALALLAVSGVDVDWPAISAG
TGARRVDLPTYPFQHRRFWLGDILSAPALPGGLAGTGAGTGSGVGAAGTQERAGEAGERT
FWDAVARGDLTEVLDVPPDTPLHTVLPALAAWRADRLGQEAVDRWSYRAVWRPVAMPPVE
GAPGRWLLVVPADGVGGTPTNGTPTNGAVVDGAVVDGAVVDGAVVDGCVRAIEGGGGQVI
AVLPVGTDSHEAERDSVAALLADVDTGGGPLTGVLSLLALDERDRSDHPAVSRGLAATLT
LLQALGDAGIDAPLWCATHAAMPAGLVGAHPAGNEPAGNEPAAAEDASGADGPSATGDAV
PTGGSASGTEPAAAAAGLSAVQAQVWGLGRVAALELPRSWGGLVDLPAVVDGPAARRLAA
VLVGATGEDQVAIRDSGVFARRLIRARPDPAGVGWRPRGTVLITGGTGALGAAVARWCAD
RGAARLVLTSRRGMEAPGASGLVADLAGRGVEVTVVACDAADRDALAAVLAAIPATSPLT
AVVHAAGVAGRFTGLRDIDIAEFADVVTGKVAGARHLDELLGTRELDAFVLFSSIAGTWG
SGGQCAYSAANACLDAVAAHRAARGLAASALAWGPWAEGGMAVDPEVAGHLRERGLRPLR
PELAVAVLERAGGAAGVRTVADVDWDRFTPIFTAARPSRLLADLPEADAALSPRAASPQG
ALTPPTAGAADTGGGAEPLRRPAGMSDPDWRRLLLAMVRAETAAVLGYDEADQVPADRAL
SELGSTSLTAVQLRARLADRTGLALPTTVVFDHPTPAALAGFLAGELTGVRPATEPAAPG
GAADHATGGGGDHGGGAAADRPPVGPAVSAVALAGPPTALRTGPADDPIAIVGMGCRFPG
GVSSPAQLWDVVVRGGDMVSGFPVDRGWDLGALFSGDPGVPGRSDVRVGGFLADVAGFDA
DFFGISPREALAMDPQQRLLLEVSWEALEHAGIDPTSLRGTDTGVFIGANIHDYMTLLSR
EPERTEGYLATGTASSVLSGRVAYTLGLEGPALTVDTACSSSLVALHVAVRSLRVGECSL
ALVGGVTVMSTPVGFVEFSRQGGLAVDGRVKAFGEGADGTGWGEGVGVVVVERLSVARER
GHRVLAVVGGSAVNSDGGSNGLTAPSGVAQERVLRAALVDAGVSADGVDVVEGHGTGTR
>A0A0N1GC06|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MPGDQEIDETHDDTGTAIDDAVAVIGASCRVPSASNPAEFWRLLADGTDTVSPWPAERGK
GRGSWRGGFLDEVGTFDAAFFGVDPDEAAAMDPQQRLALELVWEAMEDAGLRDDRLRGSR
TGVFVGVSADDYAKLAARGDRFAGGEPYEFTGRHRAIIANRASWLLGLRGPSLTVDAAQA
SSLVAVHLACESIRRGESDLAFAGGVNLILAAESMEATAGLGAFSVRGRCAAFDESADGF
VRGEGGGIVLLKPLAAAVADGDPVYAVIRGSAVNNDGGGERLTDPDVDGQRDVLRRAYAD
ARISPEAVQYVELHGTGTPVGDPVEAAAVSAVVGRGDGDRPPLRVGSVKTNIGHLEAAAG
IVGLLKAVLALRHRQLPPSLHFSAPNPAIPLDELNLRVQTELETWPAPDAPLVAGVSSFG
VGGTNCHVVLAEGPYTGRRPDTPQPRPATATGRPLPWVLSARTGRALDAQAARLLAHVEE
RQDAEVADIARSLAVGRSTFEHRAVVLGTGRAELTAALERFHDEAVTGVATTGRTAFLFA
GGGAHRVGMGRELYAAHPVFAAALDEVLGHFDPELGLRAVLFGEREGAAEDLDGMRYMQP
ALFAFQVALYRLVNSWGVEPDLLVGHSFGEIVAAHVSGALSLADAARLAAARGELMETLP
PGGAMIAVEATEPEALDALDGVDDVSIGVINGPRAIVLSGADETLTRIAEGFRARGRRTT
RLRVQNAAHSPLTAPMLDEFAHRIDGLSAAEPGVPIVSTVTGRAATGAFMTQEYWIGHIG
ATVRFHDAITACRELGVTRFLELGPDSVLTPLVQPAGTELAVALQHRDHPEPRALLTGLA
EAWAGGVPVDWQQAVGEAHAVDLPTYAFQRERYWLDERPAPVAEQHLSSATLALRERLNR
EPDGFLGRWLAEHVAETGDAASFDPDATFRDLGFDSALSVRLRNRLVSATGLRLPTSVLF
DHPTPNALAAHLHDQITGVLDDGPAAPVPVGTAADDDPVVIVGMACHLPGGIDSPQTLWR
TVRDGVDATSDFPTDRGWDLASLYDPDPSHPGTTYARRGGFLSGAGDFDADFFGISPREA
AAMDPQQRLLLETSWEAFERAGINPDGLRGSRTAVFVGAMNMEYGPRLHSPADGTEGFRL
TGNTTSVASGRISYLLGLEGPAVTVDTACSSSLVALHLAVQALRNGECTLALAGGVTVLS
TPGMFVEFSRQRGLAPDGRCKPFSDDADGTGWGEGVALLVVERLSDAERLGHPVLAVVRG
SAVNQDGGSNGLTAPNGPSQQRVIRTALAAARLGATDVDVVEGHGTGTTLGDPIEAQALL
ATYGQGRGEDSPLWLGSVKSNIGHTQAAAGVAGIIKMVLAMRHGVLPRSLHVDEPSHHVD
WDAGQVQLLTENRAWAEADGRPRRAGVSSFGISGTNAHVIIEAAPVEEESPTDDTAPVAP
EAGAVVDAVEVPWVLSARGEAALGEQAARLLERVTGGADLDVRDVGRSLVVGRAVLEHRA
VVLGSDLEGLAAGLGELAEGRAASGVVTGRAHSGDNGVVFVFPGQGSQWVGMARELLEFS
PVFAARMAECAAALEPFVEGWSLLDVVRDGDEELLGWVDVVQPVLFAVMVSLAGLWESLG
VRPVAVVGHSQGEIAAACVAGGLSLGDAARVVALRSRAIVRLAGRGGMVSVLAPLEQVEG
RLSEGLQVAVVNGPEQVVVSGVPDELDAFVAGCERDGVQARRVAVDYASHSAQVEELKAE
LLDVLSGVRPSSGRIPLFSTVSGEVIDTAVMDAEYWFTNLRQTVRFDTALESLLAAGHRI
FVEASPHPVLLGAVTQSAEHSGTAGVTAVGTLRRNEGERARLLHGLAELFVAGVDVDWSS
WVAGGRPVELPTYAFQRRRHWLAAGRSVVDAAGLGLNATGHPLLGAAVRLASQDGLVLTG
QLSSHTDAWLADHAVFGTVILPGTAFVELALHAGGEVGCDVVEELTLERPLVLSDGALTA
VQVSVGGADDAGRRSVAVHSRVQDAAEAAEWTRHAVGVLAAGPVAPAERLEGSWPPAGGQ
RVDVAEAYERLDGLGYGYGPVFQGLREVWRVGEELFAEVRLPVAPDDFGVHPALLDASLH
ALLSDDVRVPFSWSGVRLHSVGAAAVRVRLSPRADGAVRVALFDGAALAVVTVDELRLQP
MSRDQLGSAVAGDPLFEVRWAEVPLPDGSGAVPSEVVVEYVEPGGELRERLGEVLAVVRD
FVGDTDAAGARLVVVTRGAVMGTPDPATAAVWGLLRSARAEHPGRVVTVDVADDDDAEEA
VVLALASGEPQVAVDEGRLYAPRLAPVAATAEAEREWRPDGTVLITGAGGALGHLLARHL
VAEHGVRRLLLLGRRGGEGSEDLVDELTAAGAAVTFAACDVADREALTAVLADIPAHHPL
TAVIHAAGVLDDGVVTALTPERVDTVLRPKADGARLLDELTRDADLAAFVLFSSAAGVVG
TAGQANYAAANAYLDALARARRADGLAATSLAWGLWAGDSAMTAHLDDTDLARLSRSGLA
PMSPEQGLALFDAALAADRATLVPARLDPPALRDQAARGGLPAVFKSLVRAPAQRAAAVG
AADVSSWAARTAALDDAEREAALVELAATQVSLVLGHGSATAVEPARAFRDMGFDSLTGL
ELRQRLQSATGLRLPSTLVFDYPTLTALVGYLGEQVDGTAATGPALPAPVAVAADDDPVV
IVGMACRYPGGIDSPQELWQATLDGLDAITEFPTDRGWDIGDLYDPDPGRAGKSYAREGG
FLRDAAVFEPEFFGISPREALAMDPQQRLLLETAWEAFERAGIDPTSLRGSRTGVFAGMM
AMEYGPPLNEPVEGIDGFRLLGSASSVASGRVSYLLGLEGPAMTVDTACSSSLVALHLAV
QALRNGECTLALAGGVTVMSTPTTFVEFSRQRAMAPDGRCKAFSDDADGAGWSEGVGLLV
VERLSDAERLGHPVLAVVRGSAVNQDGGSNGLTAPNGPSQQRVIRDALASARLTAADVDA
VEGHGTGTSLGDPIEAQALLATYGQNRPADRPLWLGSVKSNIGHTQAAAGVAGIIKLVHA
MRHGVLPRTLHATTPSHHVDWDSGAVSVLSTAQEWPELERPRRSAVSSFGISGTNAHVIL
EAAPEAPAPDPAPAAPVIPWVLSAKTAEGVRRQAARLLARIAEEPRPDPRDTGFTLTAGR
ALLDHRAVVLGTGHAEPTGALTALARGEEHPAVVTGATRAAGAGRLALVFSGQGAQRAGM
GRELYERYPVFAEHFDAVCAAVDAHLEPIAEHPLRDVVFAPADSPLAPLLHQSMYTQTGL
FALETALLALLRDWGVTPDFVMGHSLGEITAAHAAGVLSQADACALVAARGRLMGALPTG
GAMAAVAVDEPTAEAYIARASLADAVGIAAVNGPQAVVVSGDESAVAAVVDHFRAAGHRV
RRLSVSHAFHSHRMDAMLDEFAEVLGGLEFRPPRLPVVSNLTGGLADAEQLCTPAYWVEH
VRRAVRFADGVRCLADQGVTAYLEIGPEAVLTPMAQATLDEIPGAEDHLAVAALTSGRPE
ALALARALAQPFVTGVPTAAWERLVPGGRRVELPGYPFAGQRYWQDGDAVTGGIRAAGLN
ASGHPLLGAAVFLADGQVVLTGRVLPGSHPWLADHAVGGTVLLPGTAFLELALHAGAETD
CPHVEELTLETPLVLSADSAVYLQVAVGAADDTGRRSVTVHSSATPADGGGEPPVRHATG
TLSPAPERPPATAWTWPPADAQAVPVDGLYDELAERGYGYGPVFRGLRAAWRTADALYGE
VELPVRPGAFGIHPALLDAALHGVNLGVPSLTGTDGTRPLLPFSWTGVTLAASRAATVRV
RLTAAGEDTVALAAVDPAGQPVIGVDGLVLRRMSRAAAPDRDGGLHLRWRPVPAAARPAD
AGSVEVARVEPGGDVHARLAEVLARVQGFLAEPADGDARLAVVTRGALLERPDPVTAAVW
GLVRSAQAEHPGRLLLVDADASAAPLEDALAVARASGEPQVAVRDGRAFVPRLTRSGPAL
LPVPDAPRWRLETHGPDDLALTAGEEPAPPLGPEEIRVSMRAAGIHPDDLTGDLTGVPGT
EGAGVVTETGTAVTGIAVGDRVLGLFPRGGALGRSAVTGHRDVLPMPSGWSFAQAAVPRA
FLAAWQGLGEVRAGERVLIHPGDGAVGLAGVLIARHLGAEVFATAPPGGAEVLRGLGLDP
AHLVEAGAAAHGEGAPRELDLVWDARGGGSATASTGGRYVVAETDGSTASDPARRQAVLA
ELAVPLATGALRPLPVTAQDIRTAPEAYRRLTAPGGTGPRVLTIPRPLDPDGTVVVTGAS
GTLGRLVVRHLVSAHGVRNVLLLSRGGGEAPQDLLDDGVHVQSVACDVADRDSLARALAR
IPAEHPPTAVVHTAGVLDDGVLEALTPGRLDTVLRPKADAVHALHELTADADLAAFVVFS
SVAGVLGSAGQANYAAANAYLAAFAAARHTAGRPALSLAWGLWAETSAMTAGLGAVDRGR
IARMGLLPISAREGLAAFDRALAGALPFAVPASVDPAALRADTAPPVLRDLAPAAPVRTA
AAAPAHTDQDGPESLESRLRSLPAEQRREHLLGLVLGDVALVLGHGDPRDVAADGAFRDL
GFDSLTAVELRNRLNHRTGLKLAATAVFDHPSPRALVDHLLDRLAPAPAESQDAGEPSYE
RVMADLTRIRSHLTVLELTGAQRAALADTFRGMSERPGTHPADAESVAGAEEHGSADLES
ATAAEVLDFVTNSLGISISVSGDASPTDPS
>A0A0N0N2C5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
PGQPARSSRRARGPPDPPEWGGLWATQAARGVTAREPPSPRAPPPAPPCPRHAHATIGSG
AEPAAFDLELWPPADAEPRTPPAPDHLLRGLWHHGDDLFAEVELPAEYRAEGPRHGLHPA
LLDTALRAFAPDPSQLPDTWHHLVLHAEGASSLRVRLTRTGDDTVSVAAADDTGLPVATI
GAVRLRPADPARLTDARAARSGPLLRLDWPEVRCEAPKAKPRWALVGPDPLDARPALMKA
GVYTEAYDNLGALAKALDSGTAAPEAVLVAGVPDRADPTPVRQVRQAVELLGEWLSDERF
AAVRLVFLTRGSLAAEDGATAPDPAAGALWGLVRCAQQAEPGRLVLADLDAKRASWRALP
AALASGEPQLALVAGTLRVPRLTTVPAAPSGDPALAIDPTGTVLVTGGLRPAATAVVRHL
VTGHGVRHLLLAAPGEEAAATTPLVAELAALGAGTTVLDCDPADASALAALPAAVPAGHP
LTAVVHVAGSGEDADLEREFKAALNLSVLTERQVIDPAVPLLLLSSAVGTLGAVGRGGEA
ALGAFLDALARRRRSAGLAGAASAWGSWTTADGPVGGPLDGTVRLPRTAVLDLFDAACAL
GVTGAVLLRPDTRALAGRGGDDRLAAPLRGLAGPPARRRAGQRGSAGVLSTIRRRLAGLS
DAERDAVLVELVRTDVAAVLDYPSPEAVEVTRAFRDIGLNSLTAFALRNRLRETTGLRLP
AALLFEADTPGRLATHLKEQLLRR
>A0A380N952|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces griseus|TrEMBL
MGRELYGRFPVFAEALDGVMARLDVGLERPLREVLFAQEGSGAAVLLDSTGFTQPALFAV
EVALYRLVESWGVSPGFVAGHSVGEIAAAHVAGVLSLVDACALVGARARLMRELPGGGAM
VAVGAGEAEVAARLTDGLSLAAVNGPGSVVIAGAEDEALALAAEFAAEGRRTRRLPVSHA
FHSPLVEPMLAEFREVARSLTYAEPRIPLVSNVTGALAEAGQLTDPEYWVRHVRAAVRFG
DGVRALAEAGADAFLEIGPDGVLTGLAARVLDATEDGSGGVGVPALRKDRAEEHALLAAL
ARLHTAGVAVDWAAFFTGTGARRTELPTYAFQRELYWPEPAAGSHPATAQDPVDAAFWAA
VEREDLDSLSATLELDDTVLSSVLPALSTWRRGRSERTLLDGWRYRVTWQPVPVPEAAAD
GTDGPWLVLVPAGHGDPWTEALAGAFGESAVRLAVPAADEDGTAALLGAAAEGTAYAGVL
SLLAGTGTDGTARPDTLLRLLETAGIDAPLWCVTREAVCVGRSDAAADPGRAALWGLGRV
LALEAPGRWGGLVDVGHVADARTIRRLRAVLTTAAPAGTAEDQVALRTSGVFGRRLSRAD
APATDVTWRPAGTVLVTGRAEGFGGHVARWLAAHGAAEVLLAGPGDADEAVTTALRTEMA
AAGAVLTTVRHTDPADAAPLVEALAALAADRPLTAIVHTGDTGDTGDTGDTGAEDAPGIN
EARAAYEALVTAAGSRQLDAFVVFGSISAVWGVTGQGAGAAAGVCLDALVQQHRASGTNA
VSVAWGAWQGAGPEGLAAHLRANGLPAMDPARALDALAPAIGAGAADPAAPASVTVADVA
WDRFAPAFTRARAGLLLTGVPEARAALSDAGGDGADAGTAAELRERLRQSDPAERVRALL
ATVLTEVASVLGHADAGDVPAENAFKDLGFDSLTAVDLRNRLATATGLTLPATLVFDYPT
PTALAGHLLTELLGEDTAPGTGDLSARGAADADDPIVIVGMSCRYPGDVRSPEDLWAMLG
SGTDAIGGFPTDRGWDLDKLLHGDRDGRGRSVTREGGFLYDVADFDPAFFGISPREALVI
DPQQRIVLQAAWEALERAGIDPAALHGGDTGVFVGGGSGDYRPPSASPGTSRPPSPRASS
PGGSPTPSGWRAPPSASTPPARRP
>C8W6B3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Desulfofarcimen acetoxidans (strain ATCC 49208 / DSM 771 / KCTC 5769 / VKM B-1644 / 5575)|TrEMBL
MKKNIKSIYEPIAIVGMGCRFPGGVNTPAGFWELLRNGVCAITETPSDRWSNDLFYSKDR
EKPGKINAIHGGFLDRIDLFDPYFFGISPHEAAWVDPQQRLLLEVTWEALEDGGQKPVEL
EGTDVGVFVGALALDYHTLQFSDMLQYDMSPYTSTGSMGTMLSNRISYIFNFRGPSLTLD
SACSSSLVAVHYACESLRRGECSIAVAGGVTLMFTPQHSIAEAKGGFLSSSGLCKSFDAG
ADGYVRGEGVGIVVLKPLDRAIADNDQIQAVILGSAVNQDGRTKGITVPNSEAQEAVLRM
AYQKAQVEPSRVRYIEAHGTGTPVGDPIEANTLGRFFSAYSDGAELIIGSCKSNIGHTEA
AAGVAGLIKAVLCLKHNKIPPNLHFNRPNPKIDFEKYRMKVPTNVTAWPENAEDAVCGVN
SFGYGGTNAHLVLSRMNSYCKANETKHKVLTRPFLLPISARSKDSLREYTKAYGQLSSGI
YSSDELFDLCFSAGMRRDHHSYRMGIVFQHQAELVRQLEGYFRDGYSSSIVSGYASANPS
PRLVWAFSGMGAPWWGMGRVLLEKEEVFQQAVTRCDRIFKEIAGWSILEELTRDEVSSRM
NEAWVSQPANFALQIALAALWRSWGIKPDVIVGHSVGEIAAFYEAGCLELKDALRLVYHR
SQLQRRLEGRGTMLAVGLCATEAEILCREFSRISIAVVNGPASVVLSGDREKLESIALSL
EKKGIFAKMLNVNVPFHSSCMDEILDEFGECLKSIVPHSAVCPLYSTVTGGIIQGFEADA
GYWQRNLREPVRFAPVIQSLIEEGFDTFLEIGPHPVLSVPISECLGTKNGTVLYSLHRRE
NDQQTMIRSLGVLYTRGFAIDWSKLYPGGKTTSLPTYPWQRESYWVEPDSGRRVRLGLKD
HPLLGIRMPQAIPMWENEISLEKQPFLADHVVTGRTMYPGACFIEAAYGALHTLFCDKSC
YILEEIEFKKGLTVTGQNILQFYLDREQAAFSIFASADFGRTDMALRASGRIRQTPGTDC
LNIVDINAIREKLASYLSSTVIYTRLKDIGFAYGPEFQGIYEACVGLDEALAEVRMPCRN
EEVDSSYFFHPILLDSCFQALLLADMGPESGCRNKEIQIPVKIKSMRVLRRPPERLFAHA
RVVSRDESSTTGDLWIYDDAGFLVAEIRGFLKQTADMAVLHIDRKTLDSWVYSVCWTHKN
NINLHGDSSVGFRKAPVNSLWVIFSDNSGLGEKLAFSITARGGAAVLVFPGEALSASSDG
TAFKLSPQKEEEYLSLFQSLKSREGQVCHRIIHLWNLDAGGGEKIRYADYVQSRTLGCLS
VLYIMKAMEALNITAKLWITTRNAWPAGDDKTGLNIFQAPVWGLGRIIGHQEMLRNWGGA
IDLSQDALGNYEADLILNEILNPDGEDQIAWRNKGRFVLRMKRASRINPSFPASFRADGT
YLITGAFGALGKEVVKEMVRCGARHLVLMSRSNIPDRCEWDSADQNSSLGKKVAFIRQLE
KAGAKIYIAAVDVGDMEQLNEFLTRFRENEGLPFRGVMHCAGIVRDKLLNQMDEDTFNAV
LGPKVWGAWLLHEAMRGEPLEYFVLFSSISSLISFPGQGNYAAANTFLDALASYRRGLGL
PALCIHWGPWTLGMARDLNLIDHFQSEGIACFSRGEGLCLWEHLIAQSVDQLGVFQVDWN
RLFQVLPFCPPMFSELLEDVSKQNILEGSGAEMLQKKLSAANSAKAKEKVIGEYLFDLIV
EKMNFDRSLLDEEKSLPALGLDSLMAVNLRVRVFQDTGVALTAGELLSDRPLKEIVSLLT
VSIQ
>A0A1V2RU60|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MTAEVAAVVDEDLSGTWPPAGAEAVPLPGFYERLAEDGYEYGPAFRGLRAAWRRGEEIFA
EVRLPEERHGDDFDLHPALLDAALHTSLVGGVDEVRLPFSWAGVTLHATGATALRVRLTP
TGPDTMSLALADETGAPVATVESLAVRPVRAEQLRDVVGDALFGVDWAEVPPVSADAPHQ
APVESAELLPGEPAPPAVALRWLPEPGGDPAEAVVRALASLQEWLTDGRFVASRLVWVTR
GAVSVSEGEDVTDLAGAAVWGAVRSAQAEHPGRIVLVDLDAASADGGGEPAVLPSALPLD
AEPQLAVRGGRVLAPRLARLRRPAAAPAWPGLGGTVLITGGTGTLGGLVARHLVEAHGVR
HLLLVSRRGPRAAGADRLVTELTGLGAEVTMVACDAADRDALAAVLDTVPADRPLAGVVH
AAGVLDDGVLGSLTPERVRAVVRPKADAARHLHDLTRDADLSMFVLFSAAGGVLGAAGQA
NYAAANAFLDALAQRRRARGLPAVSMGWGLWEAASGMTGGLDGTDRARMRRSGVLPLASA
DGLALFDAALAEGRPVVLPVRLDLAAVREAQEPPPLLRRLVDTAARRVVRARAAVGAGAE
RDAAGFPGGLAGLPAAERAEALVDLVRSHVATVLGLAGPGQVDVGRGFLESGFDSLRAVE
LRNRLGAATGLRLPATLIFDFPTAAALAAHLDAQLVPESAVPPVLARLDGVEAGLAGLSP
DDPVRGLLAARLQSLLTRLGGNGQNGGNGENGENGAGRPGGTNAGGSGEIEAAGLEEIFD
IVENELRNS
>A0A1V2RRL3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MHSAGTATGALVVDTTAAELEAVSAVKVGGALHLHELTLERGLDLDAFVTFSSGAAVWGS
GILAAYGAANAALDALVARRRAAGLAGTSVAWGLWGGGGMGAGEAGEQLSSYGLRPMAAE
RGIQGLAQALDDGEDQLVVADIDWDRFLPTYTVFRPSPLLSTVPEAIRANAAEAENEQEA
ETSIEAAALRKRLAAAPSPLERETILLDVVREHAAAVLGHTGAAAVQPDTTFLEQGFNSL
SAVELRNRLARVTGLRLTGPMMLDHPTPTATAAHLRELFATDQAGEGGTDQPAPRFLLPA
APQADGPPAGPPDPRAAASSSLTALYLRAHSSGRGADAMRMITGLGAFRPSFTSPEELAG
IPPLVPLTRGPEGPTLICLPSFGGTADAQEFVRLAHGFRGKRQILAVTVPGYIPGEPLAA
GPDALLDLYAGTVLGSPEAAADAGPFVLVGYSSGGVTAHALAARLAERGRPPAALVLLDT
FTPDRAGVSDEVISELPAAVLANNVGADGIGGDDWLIACGHYYDFDWRAHLPHAAGLPTL
LIRHADGDDGAADFVQVPWAYSGDVTPVAVPGDHFSMIGSRAETTALAVESWLATRFTAT
QDRDDD
>A0A3R8B0H5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii CAST|TrEMBL
MAADLKALAEKAGLRGISNELGIRVLVEAVRNSKTVVTFLAQSFIWKRFVQRFDVVPPFF
SNIEFETASPGAFRVLYSSMTPDELHTYVSNVVLDTARQVLGTSELPALDSPLQELGIDS
LGAVELRNSLSQRLGVKLSATTLFDYPTIRAIIDYIVNQVSGEASAAKATSGALVSAGLA
AGRNSPIAVVGYSCRLPQGSETPDKLWEMLRRAQDCVVEVPLTRFDVDMFYDSDIDAKGK
MYVRKACFMDDADMFDNSFFNISAAEVTYMDPQQRVMLEVAYDAFYSAAYSREHLIGKNY
GVWIGCCNSDWHFLEQQSNPDKSSSYSGPGGSGCLVSNRLSYVFGLKGPSMTIDTACSSS
LVAADCGAQAMRFGYCDGALIGGVNLMLSPQLFLAFCKARMLSPDCRCATFDEKANGYVR
GEGAGAIMLRHLADAQREGKRILGIVRGTAVNHDGRSASLTAPNGPAQQDVIRSALQIGG
VDPLDVALVESHGTGTALGDPIEMGAIKAVYGAGRSADSPLVVGALKSYIGHLEGSSGIA
GILKVLLCLRHHEVPPNLHFDTPNPHMDLSDFHVVLPKKQMKLQPAQKSSTILGSVSSFG
FGGANAHVVFEEYPEPTMATDVGGERRSTEAAESAGKKRLAFLFTGQGSQYPNMCKQLYE
EEPVFRSHMDACFTVLEGKLDVKLRDVIYPTAENDVEMLNLLNQTGYSQPAIFCVEYALA
QLMISKGFSPSVVMGHSLGEYAAAAIAGVMDWKDALLLVHERASIMQHIDPNDGVMYACR
ASEQDAQAAVEKALGEKAVAVTVSAINGPRSIVLAGTQPDVLAVLKAMDMQSRAKQLTVS
HAFHCPLVGEAAALLLPKVESVKLSNPNEGITFISTVTGKAVGAGELTKPEYWATHITKP
VQFLQGMRAAVTSGEAGIFIEIGPRPTLVNMGQQCVPRNDYTWVAPVDPKDSNRNSFPQA
LEKITSNMVCTYTWKRHAFPWTVVVHPFVDKFVPDQDETKATSQKLLTPAVGELLHDHVV
NGTAMMPGVGFLEAMAAGGFMMVDGKLPSTVVALRDCEFERPMLIPKIDPSTGEFTQAAK
LMITVNNKDITLKSIMDGEEEEIFHSRCTFSLCPATSLPTEPADLLTSLQGRITTPVPIT
TLYETLQSVGLQYGARFQSIRECYAAASDEVLAKLRPKLPLHSFERNFRIHPVLLDGALQ
TAAVLFAEMGHKRPLVPVGVKRALLARVPAGSEVWSHVVVKSKDLRSATMDVTLFSTKGT
ILGQLVDVAVRAFDAVAGAQIPKGLLWEVSWVPKAKAPVEDGVDTVENEASETITPTAKL
AVKPTGKVEGLARQPAVNGQPKWLLLKTPSSMLEGLQKALQGTPSAFVKELDEKHPNNAI
SSKIHNSEWDAIIYLGALSAAASSTTCVADALLLANTLGNTAAEKPLPNVLFVTQGQHFI
RECGDVPTTAVPTQTGLYGFCRSAQLELENIIGRPVYLGTLDFAAKDPTLDDPAAFVSAL
QRVLAEADPTGAAGTCEPHTVIRGGKEMVPRLVKSSIECRGAVELHMSDRGALSMLKLRP
MPKSARVPPPRDCVEIRVRAVGLNFRDVLNVMGLYPGDPGPPGADCAGTVVAVGEGVEHL
RVGDAVFGIAQGALKTFVTTSAHLVRPLPGRLTFEQAAALPVVASTVEYALHDVAKVKKG
DKVLIHAVTGGVGLAAVQFCKRVGAEIYGTCSGGKKEEFARSVGVKYITSSRDPKKFAED
MCEFLGNGKHKIDVVLNCLIENYIPETLKFLAPNGRFVELGKRGIWTREQMGTVRPDVLY
ETVAIDTMMEEDPVWFGGMLDRIRNLVDGSMLQPLPLHTFEMTDSSEGGVAAFRFLQRAQ
HIGKVVIRLSSALEVKNFTTNSRQETENEDSGERHTLSPATAVGKPLSQSVADQMHKTYI
ITGGTGGLGLVVAQWLIEEGAHNIVLLSRRGEPPSSVKAGDPVWKYLCGEEQPNCISVAT
LKCDVSQKDDLLRVFKEIESRGLPPVAGIFHAAGVTADAALASQTADSVDQVYLPKAIGA
WNLHDACEALGLNKSLEVFMMFSSVAALLGNFGQANYSAANACLDALAMYRQSLGLCGQS
IQWGPWIEQGMAAQLTQHLEKVGMRGITNELGLRVLGDVMMHPTVAVVGAQSLQWRKFLR
RYAFEMPSFFSLVPMAGAGSSEASVNLATITKEDLCELISSLAQAVSGAAEKPAVDTPLM
DLGLDSLGAVEFRNSVADKVGVKLPQNLMFENPSISSISDYILDKAAGKHGESGVTGANG
GSGEGSDIPALDTPLDQWLMSVLEPAERFALYIDSFASEYGTLQKMAAEEDIITALEDLG
VEDGGDFERLHVAWDDLCNQINTAKRMAAKDIRPSSTAVSVSDHPKPRMPHPMEDVDTLL
ASLDFDVSTLRPATAPDKVKNVLLTGVTGFVGRVQLASLMQLKQRPDLRVYCLVRARNAD
HALSRIREATKEAKCWQETFVSRIVPVTGDFTQPLLGLSSEEFQELARKIDIVYHTGGDV
NLLSNYGRLRATNVLSVKAIIDLCTTYKVKPLHFASTLGQFPAFFAMFTGHFSGESIRED
STPDVSQMENFYPPSRQGYPWSKWAAERVLEGARKRGLPVAIYRLPNTYVAYKTGYTNKT
DYATALMIASIQEGVFPIGAATAPLTPVDTICDMLVEASFLEKPKHWVYHLFDPRLVTRA
DLEQWSQELGISYVGVKVDEFLEAIKKRGPESPVFKFVPLMQHWRRFWFDPEERTESFPI
SNEHIFEDLPHMRWPSLREVFKNSLLYSVRMGFFPKNSKSIILDPQVALNEARRICGLQL
MGREGEDFFLHPWRVLQESARRECDLLFGGQLAVYRTVRHYFMNVMYLADAQAKCPEIEK
QEIQAPLIIVGLNRTGTTFLQNLMSTDPSNRSLRYCEMIAPYGPDGNYRPKGLPNTEESW
KKDPRIPFAQEILDSQLGLSEEWMAIHTQRAELPEEDFVIFEHCGRCYSICTEFSVPSYR
EWLASDNYKETRKAYSFHKRFLQHLQWQRPAKRWLLKMPFHLFTLEALFETYPDAKIIFM
HRDPKETMGSWASLVKHAQQSLMDNVDPSALGREELRAMSTMINRALAFRRSHPELGPRF
LDVQYQDLVNNPIGVVKSIYKHFGIPLTLAAQTGIASFCNENRKHRDKLTKHMYSLKDVD
LTDGMVQEAFKEYYDSGLCKYLSSAR
>A8KXT9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. (strain EAN1pec)|TrEMBL
MTDQAVASTEDRLRDYLRRATADLRQARRRIRELDARVHEPIAIVGMGCRLPGGVDSPEA
LWRLLDEERDAIADLPTDRGWDPERLYDPDPDRPGTTYAREGGFLADAGGFDAPFFGIGP
REATASDPQHRQLLEVAYETLEYAGIAPDSLHGTRTGVYAGVVSQAYVPPPERVPASFEG
HLMTGNATSVASGRVAYHLGLEGPALTLDTACSSSLVAMHLAARALQRGECDLALAGGVT
VMATPVLLVEFSRQRGLSPDGRCKAFAAAADGTGFAEGVGLVALERLSDARRAGRRILAV
LRGSAVNSDGASNGLTAPNGVSQERVIRQALADARLAPQQVDVVEAHGTGTRLGDPIEAQ
ALLATYGQGRPAGEPLWLGSLKSNIGHTQAAAGIAGVIKMILAMRHDRLPRTLHVDEPTP
HVDWAGGDVQLLTEARRWQRGDRPRRAAVSSFGISGTNAHLVLEEPPASDEPAAETEPGL
DSDEPATGGQAGPAAGTGDTRPPAADPAAAPWVLSGRTEAALRAAAGRLHERLDADPGLD
PAEVGRVLAVGRTAHPHRAAVLPGSNRRRLEALAALAGGRPGGLVAPGGPGGRTAFLFTG
QGSQRPGMGRHLYANRPVFAAALDEVFAAFEPLLDRRLPDLMFTEPGTDEAALLDRTEYA
QPALFALETALYRLLVDLGPEPDLVAGHSLGGLTAGHVAGLLSLADAAALVAARGRLMQA
QPTGGLMAACEATADEIEPLLAAQDGQDGQVSLAAVNGPRAVVVSGDAAAVARVTAAVAA
RGGRTRTLRVSHAFHSAHMDGALAPFREVVAGLRFQPPVLDVVSELTGRPASFEELRDPD
YWVRQLRSPVRFADAVATLHAAGATTFLEVGPDAVLTPMVADCLPVGAGAAGAGQVVAVP
ALVRDRPEEQVLATALVWRHVRGADVRWDAWFGPAAGPPPHLPTYPFEHRRYWWPAEVVA
APAGPRPVTAEVAEVPAADQADQADPPVAADRGEVLLALVREHAAEVLGHPDPDSIGADD
NFLEIGFSSFTALEVRNRLCEATGLTLPAVLLYDHPTPTAVVRFLEESLVA
>D0LMV2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2)|TrEMBL
MNPAQRRDGAPIAVVGMACRYPDAASSAELWQTAMAQRRAFRRIPDVRFRAADYVSPDPD
HTDSTYVTEAGVLTNHGFDRVRFRITGSTYRSTDPVHWLALEVAAEALEDAGLGNDFPRA
STGVVLGNTLTGEHTRASTLRLRWPYVRRVVAAALAEQSWAPDALTTFLDALEARYKVPF
APMTEDSLAGGLSNTIAGRICNHFDLGGGGYTVDGACAASLLSVITACSALLAGDMDVAL
AGGVDLSLDPFELVGFARAGALARDEMRVFDERSAGFWPGEGCGVVVLMRLEDALARGLR
IQAVIRGWGISSDGQGGITRPEIDGQLRALRRAYARAGVSADSVSYFEGHGTGTRVGDAV
ELEALSRIRREASPNVAPAAIGSVKANIGHTKAAAGIAGLIKAAMALQARVLPPTTGCAR
PHAILIGPAPALRVLPHAEPWPADQPLRAAVSAMGFGGINSHVVLDGPPAPASSHARTGD
GGALAWSWCSAAQDAEIFLLADTDRTGLLAQIDRLLGFADRISRAEMTDLAALLADEVSG
ELSSGPASRPWRAAVVAARPDELARQWNLLRTRLDGHAEAGARLGISRPGARIALLFPGQ
GSPVRLSGNAWSERFAPIAALYEHAALPAEGDAQSTAVAQPAIALASLAGLRALAAVGIA
GDVAAGHSLGEFAALCWAGAVDERTLIRLATLRGRIMEETATQGAMAGISAPVAEVAALL
RECVSPGQAVIAGHNAPRQTTIAGAPSAIDTVVERARAQGLATTRLPVTRAFHSPFMEAA
VAAFQQALHDVPMAPLVRPVVSTVTGAPIAGDDLIELLAKQLAAPVRFVEAADALGPVDV
CIEVGPGRVLAGLVAQHPTLQQAAAVSLDVASDSVRGLLDAVAAAFVAGAGVQPRGLFAD
RFTRPFSLAWTPQFLRNPCEDVAIGDLDAQSASQKAQRAPAITARAAAPNAPWSILGGAA
GAALDVVRRLVAERAELPMDAVDGHSRLLADLHLSSIAVADLAATVARALKRVPPAAPTE
LAAATVAELAAAIDALPGADAEIAPDARPPAGVAQWVRAFTVVQEEHPLPARARTRDTAS
SAWRVLAPPGHELASALADAFATLPGDGVVVCMPRRPEEPHFELLLEGARAVLAETAGSE
VRTRPTRFLLVQHGGGASAFARTLAQEAPHLDVCVVDVPSGEPTAVAHVMAEAHTIGNYS
EACYDAQGRRTRPALRHLPLAQISGSLPLSPDDHLVISGGGKGIGAECALALARETGVRV
TLLGRAHPDDDPVLAANLRRFADRDVRYLQVDIADGRAVRVAMSEAVRLAGRPVTAILHA
AGHNRPRRIRDLDAAAFRATLAPKVDGIGHLLDAVEPASLRLLVAFGSVIARVGLHGEAD
YALANEWLTRRIEDWRAAHPHCRCLCIEWSVWSGTGMGERLGHIDALIRAGITPVPIDEG
IGLLFDLLRRLALEPAMPVGIVACGRLGTPPTLRWAHEPLPLRRFLEHPRVHVPDVELVV
DTRPSLDTDYYLRDHQLDGSALLPAVMGLEAMAQAAMALTSESAPPRFENVHFDRPVTVP
TVGHTTVRVAALKQADGRVETVLRSAESDFHVDYFRATCVFGAPLAPADAIATSGTDGEA
EEAGVPLQPLAELYDAVLFHGERFRRVRRYRELRAKSCTVEVDVVEARTLAATWFGPYIL
AEIVLGDPGARDAAIHAIQACIPQRRLLPVGIEQLRIEPERTMPNVAGPLRIHANERIHD
GDRFVYDLEVRDGHGQIVERWVGLTLQAVGPIAPGRAGWPHILLGPYLERVASSGVLPGI
GSIAVAIECGPDRESRRTRALSRLGINTWHRRPNGKLEPMDSTYNISVSHAADITLAVAA
PGPGLGCDLEIVSHRSGWSDILGSARMAITEHIVAEHGEGLDVAATRIWSAGEALEKAGL
APDAPLVLVRADGECIHLRSGPVAIATWVTTISGIPAPVAIALARRAESPELMHEPHHLI
TQET
>A1SVG1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Psychromonas ingrahamii (strain 37)|TrEMBL
MSTEQSPNNHDMAEEEQLSSRMQECPIAIVGMSSVFAESKNLDQFWDNIVESVNGIRDIP
EDRWAIDDYYSADKKAADKTYCKRGGFLPEIDFDPMEFGLPPNLLELTDITQLMSLVVAR
DVLADAGISDENSYDRDKIGITLGVGGGQKHISPLTSRLQGPVLDKVLKASGVDAADRNM
IIEKFKKAYIPWEENSFPGMLGNVIAGRIANRFDFGGTNCVVDAACASSLAAIKMAVSDL
LEYRSEMMITGGVCCDNSPFMYMSFSKTPAFTDGQNIRPFDDQSNGMMIGEGVGMIALKR
LADAERDGDKIYSVIKGIGSSSDGRYKSIYAPSPAGQVKALKRAYADAGFDPLTCGLIEA
HGTGTKAGDAAEFAGLSALFSENNAQKQHIALGSVKSQIGHTKAAAGTAGIIKASLALYH
KVLPATINVEQPNKNLDIDNSPLYINSETRPWMPRADAIKRRAGISSFGFGGTNFHIVLE
EYQSKQSGQYRLNEVPQTIVISAADKEALQQSLTTWRTKLAVTNDLQAYAFNALVVENPL
STPQQKLARCGFVAKNAQQALQLIEQIIKEFSLNDAPAWSTPTGIYYRESGLKTQGKVVA
LFSGQGSQYVNMGRDLSCNFPSILDTHALMDTQFSDNGLPQLSKVTYPIPAFTAEKRAAQ
EESLRLTQHAQPAIGAFSAGLYKTFLQAGFKADFTAGHSFGELTALWAAGVLSEHDYMLL
ARSRGQAMAAPEDENFDAGTMIAVIGDPAQVALEIKPLAGLSIANYNANNQVVVAGPTSE
VGVAFEQLKEKGYKVIQLPVSAAFHTALVGHAQKPFADVIDRVEFKSPSIPVFSNGSAVA
HSTQPEVIKASLKKHILEPVHFNDEIDNLYAAGGRLFIEFGPKNGLTGLVDNILKDKSDV
TTIAVNANPKKSADLQLRLAAVEMAVLGVQLNNIDPYNGLQRPTIPAKKSPLAMKLSGAA
YVSEKTKKVFTDALNDGQKINTQPANTEQSRGIEKQLPVEKEVIVEKEVIVEKIVEKIVY
LNPDGTAFDHQAVNMASVNMPPDNSTALVASIEQSVGQVVQHQAQLLSVHEEYLQGPKEY
AKTFQAVLASHAGAAQLPESLDKTLTMYHDFQSETLRVHEAYLNHQTENMQQMLTAAPMT
ESADLSAAVQQNVAVNSVAAIKAVKPATSAPVQQNKTKVATPAVSTPVPTAAIDLNEIQN
VMLAVVADKTGYPVEMLELGMDMEADLGIDSIKRVEILGAVQDQISDLPELNPEALTELR
TLGEIVDYMQAQAPVAGRENNNVPLDNIASLDNNVPEIDLSAIRTVMLDVVADKTGYPVE
MLELGMDMESDLGIDSIKRVEILGAVQDEISDLPELNPEALTELRTLGEIVDYMQAQAPA
ASIVATENESEQAKTQNSQSALLPIDLTHIMLAVVADKTGYPVEMLELGMDMESDLGIDS
IKRVEILGAVQDQVSDLPELNPEALAELRTLGEIVDYMQSQAASIVATENESEQVKTQNS
QSAPLPIDLTHIMLAVVADKTGYPVEMLELGMDMEADLGIDSIKRVEILGAVQDEISDLP
ELNPEALAELRTLGEIVDYMQSQAPAASIVATENETEQETQLKIQDSQPAASVTALLDIK
NIMLDVVADKTGYPVEMLELGMDMEADLGIDSIKRVEILGAVQDKVSDLPELNPEALAEL
RTLGEIVTYMQSQAAPLNNAVPIVPVLGSAPVDLTLIETVMLDVVADKTGYPVEMLELGM
DMEADLGIDSIKRVEILGAVQDEISSLPELNPEALAELRTLGNIVDYMVNLTGTSQADVI
KSAEPVDSVEPVASFEPAPSATVVIKHLNVIEKIAMDVNGENLLLVDDGQGCAVRLADKL
SKLGWSVTVIKPSWVNSDSDKTFSKKVNVFELNALNEQEINTILDTQSVWTSVVYLHPKT
TITAIEYPQASKQGLMLAFLLAKLSDLAAPQNNIKTRASFVVLTRQGGAFGVEDNELESD
LVQTGLTGLVKTISHEWPGVFCRAVDLASQLSADKVANIIVDELNDKNVKPVEVGFNHNG
RLTLVAEKTDSYTLQSGSSIDQDSVFLVSGGGRGVTAECVIRLAKEYKSKFILLGRSDYK
SDQPRWAIGINDQAALKKAAMQALQAKGKKPTPASISALVGSILSNREIKQTLALIDDAG
GIGEYICADVTDSNAVLNALTPITSLWGEVSGIIHGAGVLADNFIEQKTVVEFEAVYNTK
IEGLLSLLACCQQDKLKQLVLFSSAAGFYGNPGQSDYAIANDILNKTAYRFKALHPAAQV
LSFNWGPWDGGMVTPELKKMFKDLGVYIIPLAAGAELLLNELAADSNRCPQILVGNDMGG
QLPEDDVLDEKVLEDHVLKDDILEGKVLEDTSVKKPLVSRLAKRFLAANNPFLADHKIGE
NQVLPTVCAIAWMVEAAAVSYPDFVYQGLKNYQLFKGIVFDGKQASDYFIDLNTVEKKPG
GLAIEVKISGEKSDGSLNFHYAATLLMSKENQAAPLYSSELPDLVLSKQENADALYQDGT
LFHGSSLQGIQSLLECDAKGLLLSCLIPESVKSKQGEFDLQENNIFANDLVYQALLIWAR
KQLGLGSLPGSTLSWIVYGEVKVNQAFYLKLSVREQQANKVVADIILIDRDKQILAEISG
AEVTCSASLNKLFKLAVEVDG
>A0A380AV72|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Serratia quinivorans|TrEMBL
MAAAGLNPVDWRIADGMLQGKLPHVFPLVIGTDGAGVVEAVADDVSGFSVNERVAGKFMF
GVVGAGSYAQYAVIDQKAVLARVPDEVSLTTAAAMPIAAGTALKLVEKLQLSAGATLLVV
GATGGVGRFVIQLAKRQGLKVIATGGADAEAALRELGAEKVIDHHRAPVLQQVQQLYPQG
IDGMIDLVSNAEAFSALLVILRKGGVALSTIWSAAPEQMQQQGLRGGNIEAQISADELEQ
LLQSVARGELQVPVERLVSIKQAPEMLAESKAGGSRGKTVLNIDW
>A0A654SRW1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Chrysosporum ovalisporum|TrEMBL
MGYSSQGRTTLVCQPELDSGFELSIPNPQSQVFLVSGGAKGITAQCVIELARRYQCKFIL
LGRSAAEPEPVWSEGYLGEGELKKQIMEDFLAQGDKPTPAMVHKKFQTIVSRREIAATLK
AIEEVGGQAEYLSVDVTDAMALCERVAGAIDRLGAVTGIIHGAGNLADKAIERKSLQDFE
TVYAAKVQGLEHLLRCVPPSQLQYLVLFSSVVGFYGNVGQSDYAIANEILNKSAHLFKLN
HPHCHVVAINWGPWDSGMVSPALKKAFAERNIETISLEIGTQMLVRELQPKNQDSTQVVI
GSPLVYIPEVLNPQLKSFRMQRRLTLAANPFLYDHVIAGKPVLPATCAFSWIAHTCEQLY
PGYKFFSCQNFKVLKGIVFDDNRPHEYSLDLVEVAKSDNNEIEFKAKVWSNNSGKIRYHF
SANIKLKRQIPVAPAYELFNQELTKPDITTSFYQNGASSLFHGSTFQGVKSVLNISPEQI
TIDCMLPHLDEIKQGQFPVHTFNPYVVDVQIHALWIWSQHFHQVGCLPSEINNFEQFAEM
PFCQDFYISCEVKSKTESSVVADVTAHDDQGKIYSRMMGAKGIVLPRELAKV
>A0A654ZH38|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MSGLTIAVERWERMVPSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDA
ELILVIAPDFEHTDAVRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQVDAADAV
PSAGQAALAAMHRSIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSVN
GYTLFERTLADAPAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRA
ADQATVAMLRKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGV
TSAAVVDNFAAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMA
AQLRAQGRHCVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEF
TVDPLVFAADAARLQMLLDSRQFERYEGPTDPNLTIVDAVRTQLAAVLGIPQAGEVNLQE
SLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERSHTAQKVDI
SRD
>B1TB92|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Burkholderia ambifaria MEX-5|TrEMBL
MNNLDVAIIGMSGAFPGASNVQEFWRNLEAGRCSLERYSEQELLDAGVDPAHLASAHYVP
VGGRLQDIELFDNEFFGISNHDARLMDPQQRVFLQLAWHAFEDAGYVPGAHAGRVGVYAG
VSLNSYLHTVVFRSDEVDLDRDGQSILFGNLSDYLTTRLSYLLDLKGPSVNVQTACSTSL
VAIHEACQGLLSYQADVALAGACSINVPNTRGYLYSQDSFFSPDGQVRAFDERAAGTVFS
NGAGLVVLKRLDDALRDHDQIYAVLKGSAINNDGSDKVGYAAPSVSGQSAVIRDALQASD
VGPEQIQYVEAHGTGTSLGDPIEIAALTHAYAGGRRARAGTREATCAIGSVKTNIGHIDV
AAGVAGVIKTALSLRYRTLPASLGFERPNPRLGLENSPFHVNERTRAWVSDTRRLAAVSS
FGIGGTNAHAILEEAPVLEPLPATQAAYCVTLSARSAESLDALRAKYVALLRDEACPAFA
DLCYTSNVGRKAFPHRLAIAAAGAAEAAEKLAAATMRATDGAPRRLLVAVQPADADATWQ
AVRQGDAGRYAPLLDAVAHHDVPQRLAVVAVLLAAQLRRLGIAAHLQQPATLPADLVERL
SAHGDDGITRLLAEAPVDATPSDAVLTLSDAPRLQVASNEIEFGAPALQGRFMADLLASC
WAAGMSVDWPTYYADEARRKVSLPAYAFARKVQWLPVATEAERRNRKIDDIGQWFYKPTW
RETAALAARTQRVAEPAEAALLVFATDRAHRLNAPWAATTRAIHVVPGDAFAQLDDTTYC
IDPASEQDYRRLLEALDERGCLPRHVVHAWLAAEAQWDGTPANFERCQTLGLFSLIFFAR
SLHRVTVGALHARSSSPRRRWPR
>A0A2K8RGV8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MSEQEKLLGYLRRVTADLHQTRQRLQDVESAAREPIAIVGMSCRFPGGVRSPEEFWRLLS
GAEDAITAFPEDRGWDLGSLYDADPDRPGTSYAREGGFLHDVGDFDPSFFGISPREALAM
DPQQRLLLETSWEAIERAGIDPDSLRGSRSGVFVGAVAPDYGPRVHEATDGVEGHLVTGS
AISVVSGRVAYSLGLEGPAVTVDTACSSSLVALHLAVQALRQGECSLALAGGVTVMATPG
TFIGFSRQRGLAPDGRCKPFAAAADGFGPAEGAGMLFLERLSDAHRNGHPVLAVVRGTAT
NQDGASSALSAPNGPSQQRVIRQALANAGLTAGQVDAVEAHGTGTKLGDPIEAQALLATY
GRERTADQPLLLGSVKSNIGHTQAAAGVAGVMKMVLAMRHGVLPRTLHIDEPSPHVDWTA
GTVELLTEATPWPEGEEPRRAGVSSFGISGTNAHAIIEQAPPPAATDATSGTDVAEPAEA
PRTALPLVPWPLSGKSEAALSAQARRLLDHAEQHPEVTAGDIGLSLATARTAFDHRAVVL
ASDRADAVRILADHLAGRATSGLVEGVARRSVGVAFVFPGQGSQWVGMAAGLLDSSPVFA
RRIDACAAALAPHVDWSLVDVLRGGESAAAALERVDVVQPALFAVMVSLAELWRSYGVEP
AAVIGHSQGEIAAACVAGALSLEDAARVVALRSKALRALSGRGGMASVSLPVERVRERIA
AWGERLSVAAVNGASAAVVSGDADALDELLTACEAEEIRARRIPVDYASHSAHVESLEDE
IRRTLAGIAPRPSSVPFYSTVTGGVLDTTELDAGYWYRNLRRTVRFDDTVRVLLDEGFQT
FVEASAHPVLTMGIEQTADDHGTEVAAIGSLRRDEGGPERFLTSLAEAHVGGIAVDWRTV
FAGTGAHPVDLPTYAFQHQRYWLTSATTARPIDGTSAEDAADAHFWQAVEREDAEALAAT
LQVESIEQHASLGTVLPALAQWRRQRRSESTVDEWRYRVIWRPTSGTPAPSLTGPWLLLA
PGSRTGDPLVTASREALAGHGADVVLVELGEDDADRATVAERLRAATADHPLNTLSGVLS
LLPLDERPHPAHPVATTGLTLTLALIQALADLGVRAPLWCATRGAVSIGSSDPLTSPAQA
AVWGLGRVAGVEYPDSWGGLIDLPRTMDTRAGTRLAGVLAAGGPEDQVAIRGSGVMLRRL
EPAPLGNTPARRAWKPRGTVLITGGTGALGTHLARWLAHNGAEHLVLTSRRGPAAPGAED
LVAELAEQGTPVTVAACDVADRAALQRVLAAIPDDQPLTAVIHAAAHIDLAGLGATTSAE
FAQVMDAKVAGAAHLDELLGDTPLDAFVLFSSVSGLWGVGDHGAYAAANAYLDALAERRR
ANGLSATSVAWGVWDATGDNMPEALDLDQLRRRGLRFMDPALGVAALRQTLDHDQTHLAI
ADIDWDSFIPVFTSARPSPLLDELPAMRRIQEGADGAEGAGAIANASADASSGLRQRLAG
LTPTEREHTVLELVRAQVMAVLGHATSDAVDSERAFKDLGFDSLTAVELRNRLNAATGLR
LPATLAFDYPSTAVLSEHILTELTGAATDGEADVPALTNTAAGVAVTRAVPADSDDDPIA
IVAMSCRYPGGVASPEELWQLIVSGGDAIGGLPTDRGWDIEGIYDPDPDAPGRTYVREGG
FLYGAGEFDPAFFGISPREALAMDPQQRLLLETSWEAFERAGVPALALRGSRTGVFIGSN
YQEYGPRVHEAPEGSEGHLMTGSAASVVSGRVAYAFGFEGPAVTVDTACSSSLVALHLAA
QALRNGECSLALAGGVAVMPNPGALIGFSRQRGLALDGRCKAFAGAADGMGLAEGVGVLL
LERLSDARRNGHRVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRAALESARLSAAEVDA
VEAHGTGTKLGDPIEAQALLATYGQERTAEDRPLWLGSIKSNIGHTQAAAGVAGVMKMVL
AMRHGVLPRTLHVDEPSPHVDWSAGAVELLTDEVEWPDADGPRRAGVSSFGISGTNAHVI
LEHVPEEQPVAGPVTVGPEESVMVPWVVSAKSEGALRAQAERLLPYARGEAGAEASVADV
ALSLATTRSALEERAVVLAGDGEGFAAGLGALVEGVPAAGVVRGSVLPGKLTVLFSGQGS
QRVGMGRELYEAFPVFADAFDEVCALFDVELAHPLRDVVFGDADMDALDETGFTQCGLFA
VEVALFRLVESWGVRPDLVAGHSIGELVAAYVAGVLSLADACVLVAARGRLMQVLPSGGV
MVSVQAAEVDVLPLLAGCEAEVSVAAVNGPRSAVISGVEDAVMEVAGLLEAEGVKTKRLR
VSHAFHSPLMEPMLAEFRQVAEGLSYAPPRIPVVSNVTGMVADPEALCSAEYWVRHVRET
VRFADGVQTLAGQGAVTYLELGPDGVLSGMGQECVPDAVFAPVLRTGREETASVMEGLAQ
IHVRGRSVDWAALLAPAGPRPVELPTYPFQREHFWLESSVSTAETGGTDAVDAEFWDAVE
REDLPALTGTLAMTDESGAGESLAAVLPVLSSWRRRGRERATVDGWRYRVSWSPVSAGAG
TLTGPWLLAVPAGMAADPWVSACADALTGRGVRPVRVELGADDTDREAVAERLREALAGS
EATDVAGVLSLLALAAGRHDQYRSVPLGVALTLSLVQAVGDVGVAAPVWSVTRGAVAVSG
SENVREVEQAAVWGLGRVAGLEAPERWGGLVDLPEVWDARVADRLVDVVSGRVGEVEVAV
RASGVFGRRVVRASVGGSTVGGWVPSGTVLVTGGTGALGGHVARWLAGLGAEHLLLVSRR
GPGAEGVDELCAELRGVGVRVTVVACDVGDREALAGVLARVPGEFPLTAVVHAAGVLDDG
VLDGLSVGRFEGVLRAKSEAAWHLHELTCELGLSAFVLFSSFSGVVGAAGQANYAAANAV
LDALAEWRRGAGLPATSVAWGPWADNGMAVSSAEVSRTIRRNGMTAMDPRLALAALERAI
THSDAALAVVDADWERFADTFEARRLSRLLSGVPEVRKLAAATRPGDAETAYTEGASALV
RRLGTLPEAERQRSLLELVRAHVAAVLGHSGVDAIGPGRAFMEIGFDSLTAVGLRNQLSE
ATGVQLPATLVFDYPTPTALAGYLLTELLGSHQQTDGATADVATAESTATDDPIAIVSMS
CRFPGDVRSAEDLWRLLAAGEDAVSAFPTDRGWDLDGLYDTDPEALGKSYVREGAFLSEV
SGFDASFFGISPREALAMDPQQRLLLETSWELWERAGIDPETVRGSRTGVFMGTNGQEYV
SLLDRAPETTEGYVATGNAASVVSGRISYTFGFEGPAVTVDTACSSSLVALHLAAQSLRQ
GECSLALAGGVSVMVSPRGFVEFSRQRGLAPDGRCKPFAAAADGTAWGEGVGMLLLERLS
DARRNGHEVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALANAGLTAGQVDAVEAHG
TGTTLGDPIEAQALLATYGREHTDDQPLWLGSIKSNIGHTQAAAGVAGLIKMVLAMRHGL
LPGMPNVDEPSPYVDWSPGTVQLLAEATPWPETGRLRRAGVSSFGVSGTNAHIILEQAPP
RDPEPERPVVDGPVGEVGRILGTPWLVSGKSEAALRTQADRLLAHVHARAELSAEDIGLS
LATTRSAFEHRAVVLAGDRDGLVDGVAALAEGRDASGLIRGMAGADGRAVLVFPGQGSQW
VGMAAGLLESSPVFAERVGECAAALAPFVEWSLGDVLRGGEGAAAVLERVDVVQPALFAV
MVSLAELWRSYGVEPAAVIGHSQGEIAAACVAGALSLEDAARVVALRSRALRALSGRGGM
VSVSLPVETVRERLVRWGERLSVAAVNGPSVVVVSGDADALDELLAVCEGDGIRARRIPV
DYASHSAHVEAIEDELLRELAGISPRSSSVPFYSTVTGGVLDTTALDAGYWYRNLRQTVR
FDETVRSLLADGFDTFIEASAHPVLTMGVEQTAEDHGTRVTAVGSLRRDEGGLDRFATSL
AEAYVCGASVDWPGVLADTTAKRVDLPTYAFQHQRYWVEPSAVAGDVSSAGLVSADHPLL
GAAVALPESGGHLFTGRLSLRSHPWLADHTIHGTALLPGSALVELALRAGDAVACGHLGE
LTQETPLALPESGAVQLQVTVGGPDDSGRRAVNLYSRFQDGPADLPWTHHATGVLITEGP
TMPTETGLGQWPPADAEPIDIAERYPSAAALGGVEYGPAFQSLRHAWRRGEEIFAEVALA
EDMRSDAGRFGLHPVLLDAALHAVADLTADDGGGRVRLPYRWTGMSLYATGATTLRVRLA
TEPERNDGVSILLADESGHAVADVAAMVTRTFTAEQLTGGRIPHESLFRVEWMSVPQGSS
GAEPDRSHWTVVGPDGAELHTALESGGGRIDEYDDMGALLRSDASATAVPDLVLLPFLTA
SATDTVEAEGDLVSVAHQATHRALDALQAWLADARCADARLVVVTRGAVAAVPDEDVPDA
AAATVWGLVRSAQAEHPDRFVLVDLESLEWAAEAIGAAVATGEPQIAVRGGGVSAPRLTR
ALVPVASQRELVWEPDGSVLITGASGVLGGLVARHVVARHGVRSVVLVSRRGRDAAGAVE
LEAELTEIGAHVVFEACDVADREALAGVLARIPVDRPLRGVVHAAGVLDDGLVESLTPER
MDAVLRPKVDAAVHLDELTCGLDLSAFVVFSSAAATFGAAGQGNYAAANMFLDALAARRR
ARGLAGVSLAWGFWAERSDMTGHLGEVDMARMARFGMTPLSADEGLALFDAAHTAGDALL
VPTRMDVAVLREHARPGTTPALLRHLIGAPARRVIDATADGQDGASALVRRLTGLPPSER
ENVLLELVTEHAGAVLGHTESDAIAPDRAFSEIGFDSLTAVELRNRLNAGTGLRLPATLV
FDYPTPIAVARHILGEVMGSEQAGASAVDRARATPSVRKDTTDDEPIAIVGMGCRFPGGV
RTPEELWQLLISGGDAISGLPDDRGWDLEGLYHPDPDHRGTAYAREGGFLYDAGEFDPEF
FGISPREALAMDPQQRLLLETSWEALERAGIDPASVRGSQTGVFCGLTYHDYGDAVHQAG
EAAEGYLMTGNAGSVASGRISYTFGFEGPAVTVDTACSSSLVALHWAAQALRQGECSLAL
AGGATVMARPVAFVEFSRQRGLAPDGRCKPFAGAADGTGWAEGVGMLLLERLSDARRSGH
RVLAVVRGSAVNQDGASNGLSAPNGPSQQRVIRAALESARLSAAEVDAVEAHGTGTKLGD
PIEAQALLATYGQERAVEGWPLWLGAVKSNIGHTQAAAGVAGVMKMVLAMRYGVLPRTLH
VDAPSPHVDWSAGAVELLTDAVEWPETGRPRRAGVSSFGISGTNAHIILEHVPEEQPVAE
PVTEGPEESGLVPWVVSAKSEGALRGQAERLLPYARSRAEEEASVTDVALSLVTTRSVFE
HRAVVLASDRAGFVDGLEALSIGDPAPGVVHGAVVSGKLAVLFSGQGSQRVGMGRELYEA
FPVFAEAFDEVCGWFDGLLERSLREVIGGDVEGLDETAFTQCGLFAVEVALFRLVESWGV
RPDFVAGHSIGELVAAYVAGVLSLADACVLVAARGRLMQALPSGGVMVSVQAAELDVLPL
LAGCEAEVSVAAVNGPRSTVISGAEAAVSEVAGLLEAEGVKTKRLRVSHAFHSPLMEPML
TEFRQVAEGLSYTPPRIPVVSNVTGQVADVEALCSAEYWVRHVREAVRFADGVRSLADAA
VTTFLELGPDEVLSTMGEQCLPDETAVVAAFLPVARSGRGEVETALTLAARAHVRGVRVD
WTAVLAATTGRPARQVELPTYAFRRKRYWIETGVAPGVHHDTADVGEAADADFWDAVERE
DLSALTDTLAVGSEPSAGESLAAVLPVLSSWRRRSRERSQVDAWRYRIAWSPVSEVVGAL
TGTWVVAVPAGLADDAWVADCVAALAARGALPVVVELEDADADREAVGARLRDAVGADRA
ADVTGVLSLLALAEGRHGEYGAVPLGVALTLSLLQGIGDVAVGGRVWCVTRGAVAVGGSE
SPLSVDQAAVWGLGRVAGLEAPERWGGLVDLPRTLDSRALERLTAVISGATGEDEVAVRP
SGVFARRVVRAVAGAESGEAWKPSGTVLVTGGTGALGAHVARWLARAGAEHLLLVSRRGP
AAEGVDKLRAQLAESGARVTVAACDVGDRAALAGVLARVPEEFPLTAVVHTAGVLDDGVL
DGLSVERFQGVLRAKSEAAWQLHELTRELELSAFVLFSSFSATVGGAGQGNYAAANAFLD
ALAERRRAEGLPATSVAWGPWAEGGMATQDAAVSGRMERFGLPAMEPELAVTAMARAVNQ
SDACPVITDIDWPRFMAGVGGTRLGLLFGDIAEVRAARQAADATLDGQAADALRTSLATT
LSELPAPEREAALLDLVRTHTAAVLGYATHEGIDGERGFFDMGLDSLTAVELRNRLNAAT
GLRLRPTALFDYGSPSALAGHLKGELAEDEAALEKSLPAEIDRLESVLSGMPQDDITRTK
AIVRLQSVLAKLSEPGGGGGSAVRDDDIADDDLESASVDELFDVIDRELGDA
>A0A2K8RDY7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MLPDLITPLSVILRENAGRFPDKIAFEDDRHAVTYRELDARTRRLAGHLVGLGVRRGDRV
ALCLGNSVAMVESYLAVVRAGGIGVPINPQAAPAEMKYLLADSAATLALTGTANAETFLQ
SIPRAAREVSVVVADALGPDAGHTLPPGTVAYEEIVATEPVTEAPDDLGLDEVAWMFYTS
GTTGRPKGVLSTQRNCLYSVASCYIPVPGLTEHDRVLWPLPLFHSLSHIACVLSVTVSGA
TARIMDGSSADDILTALRENRSTLLAGVPTTYHHLVGIAHRTGLSLPDLRIGLVGGAVTG
PGLRRSFEAAFGVPLVDAYGSTETCGAITINPPDGHVVEGSCGLPVPGVGVRIVDPRTGQ
EVPAGQEGEVWVSGPNVMVGYHNNPQATAEVLQDGWFHTGDLARRDEAGYFTICGRLKDV
IIRGGENIHPDEIEAALRGAEGVADAAVAGMPHDTLGEVPVAWVVPGPDGVDLTRLLDHC
RTQLSPYKLPERIHEARTIPRTASGKVIRRLLADLPARLRYAADGHYEGLVLRDWSGAAV
SSDVPEELRWAVVGRDAVTDGLAAALRKAGVADVRQYADLPTSRTTPDAATYVTVLAEAD
ADTLMSARAGWAEGTGSRLVVLTRGVMGVTDRDGTPERAEVALWAAARAAQADGGHGAPL
TIVDVEASTPESEYAEALIAAVASGLPQLAVRDGNLLRPGLVRLPVVDGPDLATPTLDGP
VIVTGADTKTGAALARHLVTVHGTRHLVLVQATDTVDDRGRAELPADGVEIVRVVADGSN
PLALRAALTRTGPVTAVVHTADDPELARTLDDLTAADDLAAFVVVTDAAALLGAQPDGLA
PTVVTAALTEAVVRDRRLRGLPGSLLALGRPDEGPGAFDALIETGTPALMALWPTTINPG
DRVRTLLDTLTEQEPRATAQADETITAALRARLADLVERDQLALLGEMIRQEAASVHTHT
SAEPTPAGRSFRDLGLSSLAVVELRNRLTKRTGLRLPATVTFDHPTPEALAGHLRARVLG
LHEAAGEATGAADPAEPIAIVGMACRLPGGVASPQDLWRLVSEGRDVVSGFPEDRGWDLD
SLFDADPEKTGTSYADQGGFLREAGLFDAGFFGISPREALAMDPQQRLLLETSWEALERA
GIDPGTLKGHDVGVFSGLMAQGYGQSGATPAELEGFGETGTASSVASGRVSYVFGFEGPA
ITVDTACSSSLVAMHLAAQALRQGECSMALAGGATVMATPSTFVEFSRQRALSSDGRCKS
YADAADGTGWAEGAGVVVLERLSEARRNGHRVLAVIRGSAVSQDGASNGLTAPSGLAQQR
VIRKALASAGLSAADVDVVEGHGTGTVLGDPIEAQALLATYGQDREPERPLWLGSLKSNL
GHAQAAAGVAGVIKMVEALRHGVMPATLHADTPSSQVDWSVGAVEVLTEARTWPETGRPR
RAGVSSFGLSGTNAHLILEHSPEPASEPVVDAVDGVVPLVVSAATAASLTGQAQRLASFV
GSASDVVLPEVAAALVSRRAVLSERAVVVAGSRDEALSGLGALARGEDVRGVVVGGGVRS
GGDGKVVLVFPGQGSPWVGMGRELLECSEVFAARVGECAVALERWVDWSLVDVLRGDCPV
EFFEREDVRQPASFAVMVGLAAVWESVGVVADAVVGHSGGEVAAACVSGALSLEDAVRVV
AVRSKTISGVLSGRGGMASVGLSEEEAVARLREWDGRVEIGAVNSPSSVVISGDTEALGQ
ALDALAADGVGARQVAIDYASHTKHVEAIEDALAAAFADIRAQAPLIPFYSTVTGEWVRE
AGVLDGGYWYRNLRGQVRFGPAIADLLADGHTVFVESSAHPVLVQPINEIVDQAGTGAVV
SGSLRRGEGTSRRLLTSMAELFVRGVPVDWTGVLPAGAVAARADLPTYAFDHQHYWLRPT
PAVDAVALGQAAGDHPLIGAIVGRPDSGGLMTTSRWSVATHPWLGDHTVGDVVVVPSAAL
VEMAIRLGDEVGSPVIEELTVDRPVLLPLRGGGRAVQMTVGKADEQGRRPVEAYSRPDDA
SPDAVWTRHAHGTLMPGPVTPPASSSRWPTTSPTTDVALHEAIGDADRYGLHPALLDAAI
CTALPPGMIATRWSGVTLLASGAAAVRVRTARGAAGVTRLELVDATDAPVLNADAVVAEP
FSPEKADASAPGDLFQVDWVELLPPPGETTEEAVTTATIADAEDLADLTAVPDLLMYEAG
HSPADPREAVAAALAVLQAWLAAPALAHTRLVVMIPGAEDDLTAAAVSGLLRSAQSEHPD
RIVLVDRENAEHHDSAATVKAVQLASVTGEPRIRVRDGVTLVPRLKPAPLTENPRRELTP
DGTVLVTGGTGTLGSLVARHLATEHGVRHLLLTSRSGPNAEGAAELYEELTNLGTTVTIA
ACDTADRDAVAALLAAVPDAHPLTAVVHTAGVLDDAVVTTLTPDRLDTVLRPKLDAALHL
HDLTRHIDLAAFVLFSSAAGVLGNPGQGNYAAANASLDALALHRRRSGLPGISLAWGYWN
AATAMTRHLGAADLHRTRSLGMAGLSTAEGMALLDMALRAGEETPAALVATRFDLPALRA
STRAGTPVAPLLRGLAPVPRPVAASSHTAVTGSLRQRLDRLGAKERTEALVELVRRNAAQ
VLGHSGADGIRVDRAFKDAGFDSLTAIELRNRLAAATTLTLPSTIVFDHPKPLLLADHLR
VRLFGDDEQRQENDQHGHGTVAALSDDPIAIVAMACRFPGGVESPEDLWRLVTEGTSVIG
EFPDDRGWDIDSHYDADPDRIGKTYVRHGAFLDDATGFDAAFFGISPNEALAMDPQQRLF
LETSWEAFERAAIDPTGPGSKDVGVFVGVNSHDYTVRTHHAPGVEGFRLTGNSGSVISGR
IAYQFGFEGPAITIDTACSSSLVALHLAARAIQQGECSMALAGGVMVMGNLETFVEFSRQ
RGLSPDGRCKPFADAADGTGWSEGVGVLLVERLSDARRRGHQVLAVVKGTAVNQDGASNG
LTAPNGLSQQRVIRKALADAGLSTSDVDAVEGHGTGTVLGDPIEARALLDTYGQNRPADR
PLWLGSIKSNIGHTQAAAGVAGVIKMVMAMRDGVMPRTLHVDRPSTHVDWSTGAVQLLAE
ARQWPDAGHPRSAGVSSFGISGTNAHVVIQQAPAEDATPDQAHGAEPAPSHSAGLPTPVP
VSARTAAALRAQAGRLARFVDARPELSLTDTAHALATTRAQLDYRAVLLATDRQQLADAL
RALSNGTPTAATITGRPSEGKLAFLFTGQGSQWAGMGRELAERHPVFREAFTAACDAVER
HLDGHLARPLRHVLFAESGTAEAALLDQTLYTQAGLFALETALFRLFGSWGVRPDLVAGH
SVGEISAAHAAGILDLAEAGELVAARGRLMQALPEGGAMVAVQATEAEVAPLLDVTSGEI
AIAAVNGPDAIVLSGAQDTVLDVAARLADQGRKTKRLKVGHAFHSPLMAPMLDEFRAVIA
RLRPRPATIPVVSTLTGTPAKDGQFATPEYWTDQVRHAVRFADAVTALRDQGARTFLEIG
PGNSLTSLTLGALGTDHGDCFATMSEDDSEETAVLTALAELHVRDADVDWPALLGTPATE
IGTELPTYAFQHQRYWVEPEISAAGAEALGARATGHPLLSTAIEIPGDGPTGLVLTGRLD
RRALGRLLDPGTGAVPAAALLDLLVHAGTVAGSGAVEQITIDSPPTVPEHSHLQLRVRVD
GPGRDGLRPVVIHSRRSGDEDGTWTRHARALLRPGLPTPSFDLRTWPAAGADALADLLDP
QESGGIHGLMEQDGRLFANLSLPPELVDQAAGFTLHPALLDSVLRLLADRTGESGRDLTT
CTDLAVFAEGATALRLRATPVDGGRHRVELADHTGEPVAVLGPLALSSPTSDTIDATVAT
PAPGETHTTKDGQLVRRIVGRPAAEKGSLAHRLAALDATEQQRALLDLVQESAAVVLGHT
GAEALEENRPFKDLGFDSLSAVKLRNRLHDFTGVSLPSTVVFDHPTPATLAGHLRIELLG
EEVVPEPAEGVRPGPAVPAESDEPIAIIAMSTRLPGGVDTPEDLWRLVIDERDALSVFPH
NRDWDVDTLYHPDPAHPGTTYTRVGGFLHDAAQFDAKLFGISPREALAMDPQQRLLLETS
WEALERAGIDPLSVRGHDIGVFTGIVHHDYVTRLRQVPEDVRGYVMTGTSPSVASGRVAY
VFGFEGPAVTIDTACSSSLVAMHLAAQAIRRGECSLALAGGATVMSSPDAFVEFAGQRGL
SPDGRCKAYSSTADGTGFAEGVGVVVLERLSQARRNGHRILAVMRGSAVNQDGASNGLSA
PSGPSQQRVIRRALSDAGLSTKDIDIVEGHGTGTPLGDPIEVQALLATYGQDRPADSPLW
LGSLKSNIGHTQAAAGISGVIKMVEALQHGVMPPTLHVAEPTPQVDWATNAIALLTQARE
WPATGRPRRAAVSSFGVSGTNAHVILEQAPVEQPAATATPTEAVGPLVVSAASKASLAGQ
AARLATFLETSENSAPLDAVAAGLVSQRTVLSERAVVVAGSRAEALAGLHGLARGESRPD
AVAGSAVAPGRTVLVFPGQGSQWEGMGRELLDSSPVFAQRVGECAAALEQWVDWSLVDVL
RGDVPAEMLERIEVIQPALFSVMVGLAAVWESVGVVPDAVVGHSQGEIAAACVSGALSLE
DAARIVVLRSQLFADELVGRGAVASVALSGQDAEELLAPYGGRLAIAGVNSPRSVTVAGA
HEPLEELVAALTGRGIRARIVPSTVASHSPQVDRLRDRIAELLSFVRPGKGRVPLYSTVT
GEVLHGPELTSDYWFENCRRPVDFEPVVRKLLADGHTVFVESSAHPVLAQPLNQIVDEED
DNVRLRTVVGSTLRRDEGGPRRLLTSMAELFVRGVPVDWTKFLRAGAGHVDLPTYAFDRR
HYWLQDAATADDSGAFDNDADADFWSAVEQTDADSLAGLLAPDSAGLRDALRTVMPALAD
WRGRSRRRSSAERLRYAVTWRPLDREVSRVPAGRWLAVLPPGCPAETVTGSRVAELIAEL
GAQGLDVVPFETVPSAFTHTGLTARLSDIRAEYQPAGVLSLLALDGEQDAIDTVARTLAL
VQALGDAGLNGPLWCLTRGAVNTGIQDTAGEPGDAAIWGLGRAVALEHPDRWGGLIDLPA
TADAHTAQYLVGALNGTAGDQLAVRRPGLYSRRLVRKPASQTPADGGWRPHGTVLVTGGA
EALGIHASLWLARSGARRLIVTTTAQAPADAVTELQGKLAAAGVETTVVSCADADRETLA
RLIAETPREQPLTAVVHAADAPWTSAVADTGHADLTEVFAGKVDTAVWLDELFTGTDAAP
LDAFVVFSSIAGIWGGGGQGVSGAAGAVLDALVDRRRGRGLAATSIAWGALDGIGLGMDE
AAAAQLRRRGVLPMAHQVAVTAFEQAAEAREKAVTVADMDWEAFIPAFTSARVSPLFADL
PEAAAALRSSQPDAENGDITSSLVDSLRDVPQAEQNRLLLRLVCGQAATVLGHSSGESIG
PLQSFQEVGFDSLGAVNLRNSLHVATGLRLPATLVFDYPTPDAVVGFLRSELLTETSDDL
EGREDDLRRVLAQVPLSRLREAGLLDTLLSLGGSVDGSVPEAAAPEPAPAAPAAEDAAVI
DVMDVADLVKRALGSNPN
>A0A2K8QWX5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MNEEKLLDYLKRVTADLQQTRQRLLEAESADQEPIAIVAMSCRFPGAVNSPEDLWRLVAD
GTDAIAEFPMDRGWDIDALYDEDPDRPGTSYTTEGGFLENADQFDPAFFGISPREALSMD
PQQRLLLETSWEACERAGIDPMSLRGSRTGVFVGTNGQDYSMLTLGAAESLEDVEGHSGT
GNAASIVSGRISYTMGLEGPALSVDTACSSSLVALHLAVQALRQRECTLALAGGVTVMST
PSAFVQFSRQRGLAADGRCKPFGAAADGTGWGEGVGMLLVERLSDAERNGHQVLAIVRGS
AINQDGASNGLTAPNGISQQRVIRQALTSARLSVTEVDAVEAHGTGTSLGDPIEAQALMA
TYGQDRPADQPLWLGGIKSNIGHTQAAAGVAGVIKMVMAMREGVLPKTLHADEPSPHIDW
TSGAVSLLNDSIPWPDRDHPRRAAVSSFGMSGTNVHTILEQAPEAEPAEADEAEAVDGPV
AWPVSGRGAEALRAQAGRLREFLVERPELGVAEVARSLATTRSAFEHRAVVTGTDREALL
QGLEAIAEDAATANGVVRGRTGDAGRSVFVFPGQGAQWVGMAVGLLESSPVFAEAIGECE
TALSAYVDWSLTDVLRGAEGAPGFDRVDVVQPVLFAVMVSLAKLWRSAGVEPDAVMGHSQ
GEIAAACVAGALSLEDAAKVVTLRSQAIAVGLAGRGGMVSVGLPVDQVKERIAAWDGAIS
VAAVNGPGSVVVSGDPGALDEMVAQLEGEEIRVRRVPVDYASHSAHVEAIHDELLRVLAD
LKPRTSEVPFYSTVTGEPVDTADLDAEYWYRNLRQTVELEAATRRLLDDGHTVFIEASPH
PVLTLPVQQTVEAAQARAVVVGTLRRDEGGLERFLTSAAEVFVRGVTVDWTAVIGGRSAR
RVELPTYAFRRQRYWLDVSAAEMSATVDALGADAVDARFWEAVEREDLEALVRTLEVEDE
EQQSSLTALLPALSSWRRQRREQNTVDSWRYKVVWKPLASATDTALSGTWLVVLPASHAD
DALVSATVNGLETNGADIVRVVLDASGNDRWTVAERLRGALDAAGVEPSDVAGVFSLLAL
DESGHPAFGVVPGGLAAMVGLVQGLGDAGVVAPLWCGTRGAVSVGRSDRLVSPVQSMVWG
LGRIVGAEYPQRWGGAVDLPETVDGRAAARLAGVLAGEEGEDQVAVRGSGVFAKRMVRAT
AAEDAEGRGTWQSRGSVLVTGGTGALGGHVARWLARTGAEHLVLTSRRGMEAEGAAELKA
ELEELGARVTVAACDAADRDALAAVLDAIPSELPLTAVVHTAGVLDDGVVDALTVRRAAG
VLRPKVDATRNLHELTAGMDLSAFVLFSSGAATLGGPGQGSYAAGNAYLDALALQRRADG
LPATSIAWGAWAGGGLGSGEVGERMDRSGVVGMVPELAISGMQQALELDETFLVIAEIDW
DRFQPEFVGSRPNALFREVPELNRPAAAAGADAGDGDDAISALRREMAELSPAEQPGLLL
ELVRNQAADVLGYDSADAVEADRAFRDLGFDSLTAVELRNRLGVVTGLRLPVTCVFDYPT
ATVLARYLHTEMFGEQPVTGGATAAAPKRPEALDKPVATDEPIAIIGMSCRFPGGVRTPE
ALWDLLMAEGDVISGFPEDRGWDIDGLYDPDPEKSGTSYVQSGGFLDEVGHFDPAFFGIS
PREAMAIDPQQRLLLETSWEAFERAGIDPVVLRGSQTGVFVGSNYHDYGSRILRDAEGVE
GYLGLGSAPSVSSGRISYTFGFEGPAVTVDTACSSSLVALHLACQSLRQGESSVALAGGV
TIMATPGTFIEFSAQRVLSFDGRCKAFAASADGTGWSEGVGMLLVERLSDAQRNGHKVLA
VIRGSSINQDGASNGLTAPNGPSQQRLIEQTLAGARLAAADVDVVEAHGTGTPLGDPIEA
QALLATYGQGRPEGHPLLLGAIKSNIGHTQAAAGVAGVIKMVMAMREGVLPKTLHVEEAT
PHVDWSAGDVELLTEAVPWPETDHPRRAAVSAFGVSGTNAHTIIEQAPVADEPEAPRAAD
APDTTAVPVPWILSGRTDAALRGQAERLRDQLATFTEEFMPTVDVGYSLATTRSLFDHRA
ALVGEDRADMLRGLEALAKGETAPGVVRGMAGAAGKTAFLFSGQGAQRLGMGRELYDTFP
VFADAWDEVCAHLDGLLDRPLRDVVFAAEGSADAELLDRTAFTQPALFAVEVALFRLLEH
WGVRPDVVIGHSIGEIAAAHVAGVFSLEDACTLVAARGRLMQALPEGGAMVAVQASEEEI
APSLAGREAEVSLAAVNGPTAVVIAGDEAAALEIAEQWSGQGRKTRRLRVSHAFHSPRMD
AMLGDFRKVVEELTFASPAIALVSNVTGQPAGADEVCSAEYWVRHVREAVRFADGVRALE
AQGVTRFVEVGPDGVLTAMARDCVADRPEGTAEPVLVPVLRKDRPEARALTTALAELHVG
GVAVDWERIFAGRGARKVELPTYAFQRERYWLEALTSFASDVTAVGLVPPTHPLLGAAVE
LPDADGFLFTSRLSPQTDPWLVDHMVQDTVLLPGTAFLELALHAADQVGCDRVEELTLTA
PLPLPERGAVHLQLAVGGPDENGTRSLNVYSRLEDSTMEQPWTQHASGLLSRSGTQDDTG
QADLAVWPPEGAERIDTEDVYDRMAAGGFAYGPVFQGLRSVWIRGDEVFAEVRLPEENAS
EAGRFGLHPALLDAAVQAVMFVPQEEAGLARLPFSWTGVSLRATGASELRVRLGSLGPDS
IGLTVADTSGRTVATVDSLVLRLVAEGQIQSAGSPAAGHDSLFRLDWTPVPVGAPAPASE
GTWAVLGTDDLGVRSGFEAAGADVTAYADLAALRGAIDSGATPPDVVMVAGAAAAVGIDD
GADLAGRVRGATYRALELVRTWVTDDRFDDSYLVFVTRGAMGARSSEEVRTPAEAAVWGL
VRSAQTEHPGKFLLVDLDPEEHGDASEVLRAALTAEEPQVAVRDGRVLAARLARVAPAED
RPEPKTTPLDTSGTVLITGGTGGLGALLARHLVVEHGARHLVLTSRRGAEAPGAAELVAE
LAGLGAVAEAVACDVADRASVESLLAGIGSERPLSAVVHAAGVLDDGVVESLTPERVDKV
LRPKVDAALHLHELTRGLDLSAFVVFSSASSNFGGGGQANYAAANAFLDALAHQRRGLGL
PAVSLAWGMWEQRSEMTGELGEADLQRIARAGLNALTSEEGLALFDDALRADETVLVPTH
VDLGALRVQARTGEVPALLRGLVRVPRRRVAASETTRSGTGSLRDRLAGLSAADQYRALL
DLVRVQVATVLGHGSPEAVEPDMAFKDMGFDSLTTVELRNRLNTETGLRLSAVLVFDHPT
PTALVDHLREELLPDGGTGEPVVFAELDKLEPLLSNVMDDAEVRTQVAERLKEFLERLGE
AADSGSTAEVAERIGSSSNDELFAFIDNELGLS
>A0A2K8RGW5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MSNEDKLRDYLKRVIAELHQTRQRLEEAESADHEPIAIVAMSCRYPGGLRSPEELWRSVA
AGEDAISGFPQDRGWDVEGLYDPDPGAVGKSYAREGGFLLGAGEFDPAFFGMSPREALAT
DPQQRLLLETAWEAFERAGIDPESVRGSKTGVFTGVMYHDYGTGLTSLPAGVEGYLGNGT
AGSIASGRVAYTLGLEGPAVTVDTACSSSLVALHWAGQALRRQECTLALAGGVTVMSTPG
TFVEFSRQRGLAPDGRCKPFAAAADGTGWGEGVGMLLLERLSDARRNGHPVLAVVRGSAI
NQDGASNGLTAPNGPSQQRVIRQALADAKLSAKQVDAVEAHGTGTTLGDPIEAQALLSAY
GQDRPEDRPLWLGSIKSNIGHTQAAAGVAGIIKMVQAMRHGLLPRTLHVDEPSPHVDWSA
GAVRLLTEATPWPEGDEPRRAGVSSFGISGTNAHIILEQEPAADQDAEAPESAGQLPSGI
VPWLVSAKSESALRTQAERLLAHLDSRPEMVPSDIGLSLATTRTAFERRAVLLGSDRAAL
VEGLSALAEGSGAPGLTQGVVAGADGRVVLVFPGQGWQWVGMAAGLLESSSVFAERVGEC
AVALAPFVEWSLVDVLRGGEGDAAALERVDVVQPVLWAVMVSLAEVWRSFGVEPAAVIGH
SQGEIAAACVAGALSLEDGARVVALRSRALRALSGGGGMVSVSLPVGEVRERLVRWGERL
SVAAVNGPSAVVVSGDADALDDLLAVCEAEEIRARRVPVDYASHCAHVEVIEGELLRELG
GIGPRSSLVPFYSTVTGGVLDTAGLDAGYWYRNLRQTVRFDETVGALLADGFQVFVEASA
HPVLTVGVEQTAEEHGSRVTAVGSLRRDEGGLDRFLTSLAEAYVGGAAVDWAGMFAGTGA
RRVELPTYAFQRERYWLESVGGGVGEGAAAGLGLGSADHPLLGAVVGLAGVDGVLLTGRL
SLVSHGWLADHVVWGVVVVPGAALVELVLRAGDGVGCGWLEELTLEVPLVVPERGGVQVQ
LSVGVPDGVGRRVVGVFSRLEGAEEEPWVRNATGVLSVEGRGVVEGLGVWPPVGGVAVDV
GGVYERLAGVGLEYGPVFRGVRAAWRRGDEVFAEVALAEEQRVESERFGLHPALLDAALH
TAALGGDDSEQDSSRPGPGLPFVWSGVSLYATGADTLRVRLAPAGPEAVSLLVADTTGAP
VASVASLVTRTVSPEQLRAARNVTHDALFHTTWRAVPTQVEAPTTTGQWALLGTGAQYVA
DVGQGGPASPAAYPELADLIQAMNDGIVTPDTVLVSFTADSGARVGDPTEARGMAHRALC
VVQEWLAEERFAGSRLVVVTRGAVAAVPDEDVLDVAAAAVWGLVRSAQAEHPDRFVLVDV
DDDTPVSAGVLRAVLECGEPQVAVRFGSVLAPRLARAVAPAEGVESGLVWDSEGTVLLTG
ATGTLGGLLARHLVAECGVRHLVLVSRRGREAVGAVELEAELVGLGASVAVVACDVADRE
ALAGVLAGIPADRPLRGVLHAAGVLDDGVIETLTPERLDTVLRPKVDAAFHLHELTRDLD
LAAFVVFSSAAGTFGGAGQGNYAAANAYVDALVTHRHALGLPAVSLAWGFWAERSGMTGH
LDDEDVRRMRRGGIAPLTSEGGLALFDVSGTMTQPVLLPMRLDLPALRAQAASGTAVPAL
LRDLLSVSARRTVLPSGDGAGESGLWRRLAPLSAGEQDEVLLNLVCTHVAEVLGHAGAES
IEVGRAFKELGFDSLTAVELRNRLNTATGLRLPATLVFDYPTPVVIARHLRTELAEAYQG
AGTSVSPSGGAGAGTLATYDEPIAIVAMSCRFPGGVGTPEQLWQLLERGTDAISDFPEDR
GWDVEGLYDPDPEAAGKSYAREGGFLYDAGEFDPAFFGISPREALAMDPQQRLLLETSWE
ALERAGIDPATLRGSQTGVFAGVMHHDYGLLQGPGGGPGAPSAGSIVSGRISYTFGFEGP
AVTVDTACSSSLVALHLATQALRRGECSLALAGGVTVMSTPGLFVEFSYQRGLSADGRCR
AFAGAADGTGFSEGAGVLLLERLSDARRSGHRVLAVVRGSAVNQDGASNGLSAPNGPSQQ
RVIRAALESARLSAAEVDAVEAHGTGTRLGDPIEAQALLATYGQERAVEGWPLWLGAVKS
NIGHTQAAAGVAGVMKMVLAMRYGVLPRTLHVDEPSPHVDWSAGAVELLTDAVEWPETGR
PRRAGVSSFGISGTNAHVILEQAPVELPDTESPAERGTFSPSVVPWVVSARSEAALRAQA
SRLASFMGEHPELPTVDVALSLATTRTAFERRAVVLASDRAGFVDGLEALSIGDPAPGVV
HGAVVSGKLAVLFSGQGSQRVGMGQELYEAFPVFADAFDEVCGRFDGLLERSLREVIRGD
AGVLDETAFTQCGLFAVEVALFRLVESWGVRPDFVAGHSIGELVAAHVAGVLSLDDACVL
VAARGRLMQALPSGGVMVSVQAAELDVLPLLAGCEAEVSVAAVNGPRSTVISGAEAAVSE
VAGLLEAEGVKTKRLRVSHAFHSPLMEPMLAEFRQVAEGLSYAPPRIPVVSNVTGQVADV
EALCSAEYWVRHVRETVRFADGVRSLVDQGVTTHLELGPDGVLSGMGQECAPDAVFAPAL
RTGRDEAASLLEALARIHVQGRSVDWAAPLAPARPRPVELPTYAFQRERYWLEPAAAMAD
VASAGLGSAEHPLLGAAVTLPDSDGCLFTGRLSARTHAWLADHEVLGAVMLPGTAFVELA
LHAGGRVGCARLEELTLEAPLILPEHGGVQVRVTVSDADDSGRRALTVHSREDGGEGPWL
RHATGSVIPEPAVSAHAAVPDSVWPPKNAEPVALEGHYERLAETGLRYGPVFQGLRGVWR
RGTEVFAEVAPSDETEQEPRRFGLHPALLDAALHAVGAAAATGTSEATDAPEEIRLPFSW
SGVSVYAAGAATLRVRLSPTGTDGMALSMEVRDGTGAPVATVDSLATRPVSPEQINAARG
AVHQSLFQLNWSVLPGAEAQVNGAAAEVATLDGADWHDMAALREAIGAEGSVPPAVVCVV
PSVPTVEGGQPTGGDEIRGVIHRALGLVQGWLADERFAGSRLVIATHGAVTVEDGEDRQN
DGIAVDLAAAAVWGLIRTAQTEHPGRFVLVDLDADLDVDLDVYMDVDLDGREQASRESGR
RSLTSDTLFLLSAAVASGEPQVAVRGGRLLAPRLGRVRTAGSIPTAGSAPTAGSTPTTSL
APTTPTTGTAMASAVWDADGTVLVTGATGTLGGLVARHLVAERGVRHLLLVSRRGVDAPG
ARELEAELVAAGASVGWAACDVADRDALAAVVKGVPETHPLRGVVHTAGVLDDGVIASLT
PERMDAVLRPKMDAAIALHELTEAMDLSAFVVFSSAAGTFGTAGQANYAAANALLDALIR
RRRALGLPGLSLAWGLWDERGGMAGGLAEADLRRMGRAGVDGLSPEEGLALFDAGCAEEL
PVVVPMRLDPAKVRGTDGEVPHIMRELVRPIVRRAAADGTGAAGDLRERLAMASSEDGER
LVLDLVRRCVATVLGHGGAAAVEPGRAFKDFGFDSLTAVELRNRLGTATGLRLTATLVFD
YPTPTALAHHLHQELTGEDGGVRTAQPTLPAGEADTGHDLTTDRDLVAIVGMACRFPGGA
RSPEELWRLLAAGDDAISGFPANRGWDVAGLYDPDPEADGKSYAREGGFLHTAGEFDPAF
FGISPREALAMDPQQRLLLETSWEAFERAGIDATTLRGSATGVFAGLMYHDYGSQLRSVP
EGAEGYLATGGSGSIASGRVAYTFGLEGPAVTIDTACSSSLVALHLAAQALRQGECSLAL
AGGVAVMSTPATFVEFSRQRGLAPDGRCKAFAAAADGTGWGEGVGMLLLERLSDARRNGH
RILAVVRGSAVNQDGASNGLTAPNGPSQQRVIRAALANARLSAAEVDAVEAHGTGTTLGD
PIEAQALLATYGRAHTDDQPLWLGSIKSNIGHTQAAAGVAGIMKMVLAMRHGLLPQTLGV
DEPSSHIDWTAGAVELLTEARPWPETGRPRRAGVSSFGLSGTNAHIILEQAPVAGADDET
PEGDARLPLAMVPWVLSAKSDAGVRGQAARLLALVAGDTGPATADIGLSLVTTRAAFERR
AVVLGADRTALVKGLTALAEGREATGVVRGAVVGSDARAAFVFPGQGSQWVGMAAGLLES
SPVFAERIGECAAALAPFVEWSLGDVLRGGEGAAEALERVDVVQPALFAVMVSLAELWRS
YGVEPAAVIGHSQGEIAAACVAGALSLEDAAKVVALRSRALRALSGRGGMVSVSLPVETV
RERLVRWGERLSVAAVNGPSVVVVSGDADALDELLAVCEGEGVRARRVPVDYASHCAHVE
EIEEELLRELADIAPRASSVPFYSTVTAGVLDTQELDAGYWYRNLRQTVRFDETVRALLT
DGFQVSVEASAHPVLTMGVEQTAEDHGTRVTAVGSLRRDEGGLERFLTSLAEAYVGGAPV
DWAGMFAGTGAERVDLPTYAFQRTHFWLESEAVEVAGDVSSVGLDSAGHPLLGAAVPLPD
SDGFLLTGRLSLRTHPWLADHAVADVTLLPGTAFVELLMRAGDAVGCDRVDELTLGAPLV
LPEQGTVRLQVAVGGPDETGRRSAGVYAQTEDGPWTQHATGVLGSDGTSADRATEPEPEL
ESVAWPPAGAEAVDVTGLYERFARTGLGYGPSFQGLRAVWRKGDEVFAEVRLAEEAGQDA
GCFGLHPALLDAALHAMAFGGFVRLPKADGNAGRDEGSGTGRVRLPFVWSGVALHATGAS
ALRVRLSPAGPDAVSLTALDEAGRPVASVDSLVTRAVARDQLGAAHGAFHESLFRVEWTA
PATASPSSGAPGRWAVLAEGDTGLSAALKSAGTAGALAETYADLSALGEAIEAGRTAPDL
VFASLSSPVVLAPSAETVRVAAHRALAMVQSWLADGRFGRSRLVLVTRGAVGVRPGESLA
DPACASVWGLVRSAQSENPDRFLLLDLDDQEASFAALPQALSGDEPQMAVRGGGVLVPRL
ARVPAARATAPTSAGERDGGATATPLWDPEGTVLITGATGVLGSLVARHLVAEHGVRHLL
LTSRRGPEATGAAELVDELTASGASVSLAACDTADRAALARLLATVPAEHPLTGVVHAAG
VLDDGVIGSLTPERVDTVLRPKADAAVNLHELTEHLPLSAFVLFSSAAGVFGGSGQANYA
AANAFLDALARRRRARGLPAVSLAWGLWAERSAMTGHMDDSDVERLNRAGVAALSSEEGL
ALFDVATARAWHAWAGGPGAGGSTDVSGSGHPQTATDTDPLLVPMRLDIAALRVQAASLG
VPHLLRGLVRVPARRTAHNAASGSATGDGGVEPIGQRLHGLSGREQTRVLTELVRTHAAT
VLGHDSPDLVEDGHAFLELGITSLTAVEIRNRLNLATGLNLPATLLFDHGTPAALATYLR
AQLVPGAPESAPRDGAPAIGAAQPVSAPAAGAARAAVTGSTIEELYRQACADEQYVAGTQ
LLMAAARLRASFQTAAEVTTAPKLVRLSKGATAPGLVCFPSLVAISGPREYARFAAGFRG
RRDVSVLPEPGFGKGELLPASVDAVVEMQAEAALRCAGEKPFVLVGRSSGGWIAQAVAGW
LEARGSAPSAVVLLDTYLPRSEALPWIQTNLSGKMFDREKMFGVVDEGRLTAMGGYLRLF
SDWAPTPIDAPILTVKAEESFPGSGEGADEESAWGAALTRIDVPGDHFTMMEDFAGVAAE
TVLNWLAENV
>A0A2K8RGD3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MEPDEAIAVVGMSCRFPQAPDPEAFWRLLNEGISAISEVPAGRWTDDRPTPPGTDDPSTP
PATDASSTPPAVRHGGFIDDVDRFDPAFFGISPREAVAMDPQQRLILELAWEGLEDAGIV
PATLRGATVGAFIGAGSDDYASLIRACGRSHHTLTGTQRGMLANRLSHVFGLSGPSLTVD
AAQASSLVAVHMAVESLRRGESRLALAGGVNLNLSAETAADIAAFGALSPDGRCFTFDAR
ANGYVRGEGGGLVVLKPLSDALADGDTVYCVIEGSAVNNDGGGVSLTAPDPDGQRQVLRL
AQRRAAISPAAVQYVELHGTGTALGDPAEAAALGAVFGRSGAGPVQLGSVKTNIGHLEAA
AGIAGLLKTVLAIHHRQLPAGLNYRTPNPRIPMGELNLEMRLAPGEWPKPDNRLVAGVSS
FGMGGTNCHVVLAEPPAGTSSHASAHHPEPGAVPAPTLAPAPIPLPLSGASAAALRGQAM
RLRPYLERSPNLTDLAFSLATTRTSFDHRAVLISGQATDAAHGLDALAEGGTAAGLVMGT
ARAAGKLAFAFAGQGSQRLGMGGELSAAFPVFAQALDEVCTALDAHLDRPLRDVIHGDDA
ELLDRTVYAQAGLFAVEVALFRLLEDFGLVPDLLIGHSLGEVSAAHVAGVLSLADAAAFV
AARGRLMQAVTEPGAMVSLEATEDEVTRTLMAGGASDDGVRVCVAAVNGPTATVISGDER
AVLDLAAEWTRRGRRTKRLRTSHAFHSPHLDPVLDELRHIAESLTYRAPRIPLVSNVTGR
RATAEELCSPEYWVRHVRRTVRFLDGVRCLEGEGVTTIVELGPDKALSTLARDCLTGPGT
LVGTLRRDRPEPQALVTALAELYVSGVEVAWDPLVSGGRRIPLPTYAFERQRYWFSAPGA
EGGDTSAHGVTSGPERTDTGLSPDEAVDEGPSNNEVLDTGLGGGEVLGMVRAHAAVVLGY
ETANAIGAEHTFKQLGFDSITAVELCERLGEATALPLPGTLLFDYPTPTALAEHLHRRLH
GRTDEQAVPATVPTPDGGDPVVIVGMGCRFPGRAHSPEDLWRIVVDGEDAISGFPSDRGW
DLDGLYHPDPDRSGTSYARDGGFLYDAAEFDAGFFGISPREAAAMDPQQRLLLETSWEAL
ERAGIPAEHIKGSGTGVFIGASSVGYAADAGEEAEGYQLTGTAASVASGRVSYTLGLEGP
AVTVDTACSSSLVALHLAVQSLRAGECSLALAGGVTVMATPAMFVEFSRQRGLATDGRCK
AFAAAADGTGWAEGVGVLVVERLSDAERNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQ
RVIWQALVSAGLMASDVDAVEAHGTGTTLGDPIEAQALLATYGQDRDADRPLWLGSVKSN
IGHTQAAAGVAGVIKMVMAMRHGVLPRTLHVDEPSPHVDWSGGRVELLTETTPWPMTGGL
RRAGVSSFGVSGTNAHIILEQAPETAQPTRPIPEGDTEVAAVAWVLSGQGEAGLRAQAER
LRAFTAASPCPAPAEVGWSLASTRTTLSHRAVVVGAGRDELLRGVDAVAKGMAAPGVVRG
TGAPGDVVFVFPGQGSQWVGMALELVESSPVFAGRLGECAAALGPLVGWSLWDVLGDEVA
LGRVDVVQPVLWAVMVSLAELWRSFGVVPSAVVGHSQGEIAAVCVAGGLSLEDGARVVAL
RSKALLALSGRGGMVSVPVSADQLRDRPGLSVAAVNGPASTVVSGPVEVLDRVLAEFPEA
KRIPVDYASHSSQVEEIREGLAEALASVRLRTGEVPFYSTVTGRLMDTSELDAEYWYRNL
RETVEFQSTVEHLMREGHTVFVEVSPHPVLTVGIQDTADATDTDTDILVTGSLRRDDGTV
QRFLTSLAELHVRGVRIDWGPLFAGVSPVELPTYAFQRERFWLGADTAESAVDTWRYQIS
WNRLPDLDTPDLSGTWLAVVPEGDDEWAMAGARALAEPGRASVRTLQVPCDTDRRTLAGL
LMDVAGSDDIAGVVSFLAADERAHPTHPALSRGMAHTVELLCALTTADVEAPLWCVTRAA
VMALPTDSAPSPAQAAVWGFGRVAGLERSERWGGLIDLPVHCDAQVLRRFVAVLAQATSE
DQVAVRPSAVLGRRLEPAPRTGPANAWRPHGTVLITGGTGALGAHVARWLAQSGAEHLVL
LGRRGQKAPGAAALEDELTALGVRVTMTACDVTDRAALTGVLASVPDLTAVVHLAGTVRF
GGSLDADLDEYAAVFDAKVTGALHLDELLDHASLEAFVLFSSAAAVWGGVGQAGYAAANA
LLDAVAQRRRARGLPATSIGWGTWGGSLAPEDEQRLSRIGLRPMRPEVAVTALRHVVGSA
EPCPAIADVDWETFGPAFTAGRPSPLLSALPRLRNSSDTMAMAGERSGLRRRLAEVPTAD
QDRTLVDLVREHAAELLGHHGPAAIDPTVPFRRLGFDSLTAVELRTRLNAATGLRLPATL
LFDHPSCRAVADLLRSELLGGRSGSLAVPSATEAAPVGAVASDEPIAIVAMSCHFPGGIG
SPEDLWRVVSEGREVLSGFPDDRGWDVEALYDPDPDRPRTSYVRTGAFLHDAAEFDPELF
GISPREALAMDPQQRLLLESAWQVLERARMAPTSMRSSRTGVFIGGWGQGYPSASDEGYA
LTGAATSVMSGRIAYALGLEGPALTVDTACSSSLVALHLASEALRRGECSLALAGGVTVM
ATPSTFVEFSRQRGLAPDGRCKAFAGAADGTGWSEGVGLLLVERLSDAERNGHRVLAVVR
GSAVNQDGASNGLAAPNGPSQQRVIRQALANARLSTVDVDVVEAHGTGTTLGDPIEAQAL
LATYGQDRDADRPLWLGSLKSNIGHTQAAAGVAGVIKMVMAMRHGVLPRTLHVDEPTPKV
DWTTGAVELLTEPAEWPQEGRPRRAGVSAFGVSGTNAHVILEQAPEVAAERRQGRDEPVA
VPWVLSGANEAALRGQIERLRAFVDDNPTLDPVDVGWSLTSTRALLPYRTVVVGADLAEL
RHGLDTAEVVGAAEPDRGAVLVFPGQGSQWVGMALELVESSSVFAGRLGECAEALGPLVE
WSLWDVLGDEVALGRVDVVQPVLWAVMVSLAELWRSFGVVPSVVVGHSQGEIAAACVAGG
LSLEDGARVVALRSRALLALSGRGGMVSVPVSADRLRDRPGLSVAAVNGPVSTVVSGPVG
VLDAVLEEFPEAKRIPVDYASHSVQVEEIREGLADALASVRPCAGEVPFYSTVTGRLMDT
VELDGEYWYRNLRETVEFRSAVEGLLELGHTVFVEASPHPVLTIGIQDTADATDTDILAT
GSLRRDDGGLASFLTALARLHVRGIAVEWRAAFTGLDAHAVDLPTYAFQRRRFWAASLQR
TPGAGELDHPLLGALVPLPESGGGLLTGVLTLAGQPWLAEHSVSGVVLFPGAGFVELVLQ
AGLWLGCGVVEELTLEGPLVFSERGGVEVQVVVGGVGEGGVGGGGCRSVSVFSCRGGEWV
RHAVGVLGVGVGVVSGVEVVWPPVGAVRVGVEGVYEGLAERGYVYGPVFRGLRDAWRRGD
EVFVEAVLPAEAGGDAARCAIHPALLDAALHGIGLGGLITDDGRAYLPFSWSGVRLHAVG
ASAVRMALTPAGPDTVSLRVTDEAGQPVLSVDSLVLRPVADGQLAEAEVGNRDALYRVEW
ADVGVCSVGSLVEWGEVAAGGVVPECVVLSGVDVVGVLEVLRAWVLEERFAGSRLVVVTR
GAVSVGGEGVVDVDGGAVWGLVRSAQSEHPGRFVLVDVEEGVDGDVVPDVVGLRESQVAV
RGGRVWVPRLVAVDPGGVGVRQGLGSGVALVTGGTGLLGGLVARHLVSVYGVGELVLVSR
RGWDAPGVEALADELQGLGARVRVVACDVADRGAVAELVGSIEGLGVVVHAAGVVDDGVI
GSLDGGRLRGVMGPKALGAWHLHELTRELDLSAFVLFSSAASVLGNAGQGGYAAANGFLD
ALAAHRRALGLPAVSIAWGFWEERSELTADLAEVQLSRISRSVGTSISSAQGLDLFDAAL
AADEPMVLATPLNLPALREQAAAGTLPSILSGLVTAPVRRAVDSGRTPAGLRHQLAGVTE
AERQQRILRLVQEHVAGVLGHASAESVDASRTFQEIGFDSLTAVELRNRISAAIGVRLPA
TAVFDHPTPRLLAERVLAEVWGSLPTAAPIMPVSAVDDEPIVIVGMSCRFPGGVESPEDL
WHLVHSATDAVSALPTDRGWDLATLSGAKGGAGASYARDGGFLYDAAEFDAGFFGISPRE
ATAMDPQQRLLLETAWEVFERAGIAPDTLKGSRTGVFTGVMYHDYGSWLTDVPEDVEGYL
GTGIAGSVASGRLAYTFGLEGPALTVDTACSSSLVALHLAAESLRRGECSLALAGGVTVL
ATPQVFVEFTRQGGLAPDGRCKSFAAGADGTGWSEGVGLLLVERLSDAERNGHRVLAVVR
GSAVNQDGASNGLTAPNGPSQQRVIQQALASAGLAARDVDAVEAHGTGTTLGDPIEAQAL
LATYGQDRDPGRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGVLPRTLHVDEPSPHV
DWSAGAVELLGEHTAWPEAGRPRRAGVSSFGASGTNAHVILEQAPDTASEPEPGPARSEL
PAIPWVFSAQDEAGVRAQAVRLRAFADRNADLDPVDVGWSLAATRAGLSHRAVVVGADRE
ELLGALEGAPVVGVPVAGGLGVLFAGQGSQRLGMGRGLYEAYPVFAVAWDEVCAELDRYV
DRSVGEVVWGDDVELIGETVYTQAGLFALEVALYRLIASWGVRADYLLGHSIGELAAAYV
AGVWSLEDAARVVAARGRLMQGLPLGGVMVAVAASEGEVRGLLTDGVSVAAVNGPESVVI
SGDEDAVYAVEEMFTAGGVRTRRLRVSHAFHSARMDGMLAEFGEVLGGVEFHAPSLPVVS
NVTGVVAGEELCSAEYWVRHVRETVRFADGLDTLRELGVGSFLELGPDGTLAALTDGDGL
PVLRRDRPEPLSLMAALGGLYVRGVEVDWGAVFPGGRRVDLPTYAFQRQRFWLEPSSAEP
TTSATDAAFWAAVERGDLGSFGIDAEQPLSAALPALASWRRTRQEQSVIDGWRYRLSWTP
IPAVSGESGRLTGTWLLVVEPGGGADDLVGAMRAAGAEVRTVTVAEVAEAARLGAPETVP
ATAGVVSMLPVEETVAVLQTLRTTAPLWCVTRGAVSVVDGDVVDPGQSGVWGLGRVIGLE
HPDRWGGLVDLPGVVDEEAGVWLCRVLGGGTGEDQVAVRGGGAWGARLVRVVGSGSAGSV
VWRGGGSALVTGGTGALGGHVARWLAGAGVENIVLVSRRGLAAPGVLGLVAELEGLGAVV
RVVGCDVGVRDQVVGLLEGIADLRVVVHAAGVLDDGVLESLSAGRVGEVWRVKVGGALYL
DELTRDRDLDAFVLFSSAAGTVGSAGQGSYAAANAALDGLAWRRRAEGLVATSVAWGAWA
DSGMGAAQRQLPGMPPELAVAALQQSLVEDETALMIADVEWSSFGSRFTAVRPSPLLSEL
LPLATTPMEPVEELATRLRDMSRLERDRAVLELVRAQVAAVLGHAKPASVDPSRTFQEVG
FDSLTAVELRNRLATATGVPFPASVIFDYPTPAALADHVRTRFVPDEGEGEGEDGAGGGT
TSVLAELTRLEAALSDLSPTDMAGAEVAAKIKSLLSHWGAATNSDIEVDSATDEEMFDLL
GKEFGIS
>A0A5B7V8W4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MAGAARRPKGECRDLLVIASARGPESLWPAPPPDALLRLQEGALHAVKTLAPNTGGSAAA
LLLYPLRGHATHPSLTLITGFFRTLAHEHPSADRAVVTDADLDTCLGQLGTEMAARRDHT
VVQYRQGLRYVAQVCPAPLPTTQHGASCLGGARKLSSWPPVVRVVPPPSRVDRTLHGFLL
EAKARSANQCLPVVVPAALRDLLTTDGNRLRPLLYVLGWHDASGQCNDTAVIHTAAALEM
VHAFWLIHDDSTPAHHPHPQSPHHAPTRGGPMPHGNDRLTTALRAALRDDAHLKQEAQQL
AAMPQEPIAVVAMGCRFPERVNTPDELWQLLDEGRDAVSSLPQDRGWDLSPWQELRTRHS
IVPPMPSGAGLADAADFDAAFFDLSPREALAMDPQQRLLLETAWETLERAGIDPTQLRST
ATGVYTGIVCTAYGSPALAQPNGRPDESYGLTGTTASVASGRIAYTFGLTGPAITVDTAC
SSSLAAIHLACQALRAGDCHLALAGGASVHSTPEILLGLATLNALAPDGRCKAFGATADG
MGLSEGVGLVLLERLSDARRHDHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRAALN
NAGLKPEDIDAVEAHGTGTALGDPIEVQALIATYGEQRLAGRPLYLGSIKSNLGHTVAAA
GIAGLIKLVLALRHEHLPRTLHADEPSPHIDWDNSGIHLLREPVPWPTASNRTRRAAVSS
FGISGTNVHLVLEEAPQDAAPERADEHAEPLLFPVSAKTPDALRRQGDLLRQLVTERPEV
RPVDLAHALATTRAHLRHRAAFTARTREGLLTQLTALSKGSPAPGLSTGTAPGGGVVWVF
PGQGSPWPGMGIQLYEAEPAFRQQLDTCAKALAPWVDWDLLAVLRGTDGAPTVDELSVVQ
PVLWAMMVSLARLWESYGIVPDAVVGHSQGEIAAACVAGALSLTEAARVIALRSRAAATL
SGQGDMASLALSETEATELLAPYNRQVAIAAVNSPSSTVVSGPRQSLEDIVAQCAARGIP
ARVLDITFPSHNPTMDRLRGRILTELAEVTPRPTQYALYSTVGGHPHDTPLPGEQMDAAY
WWQNIRHPVHFHDTVQSLLTTGHTTFIEVSPRPLLLPALHEICAGASVPTVCVGSLHHDR
GTWADFLTQLGEAYVYGFPLSWSRLAARLPSGVRYRVPLPTYPFQRRRFWPAPPVNGARN
LRPVSAGPPPQPLSEEAAELVAQLAPRTAAERPSLILHTVRTHMATLIGHSSTQDIPLYT
SLTELGFDSLTATRLRQRLIRCTGLDVPASVLVDHPTAHALAAYLGQRLVLTPDTTPAEM
AKPSDGTVTADNALDAPHRGAADRRTGKLAAHVRNALDRAEPEAALKLLTRAGRLLPVFT
APPSESATMLPRLAQGPARPTLICLPSLLGGAGPFQYARLAAAFHNVRDVHLLPLPGHRP
GSQLPDTLTTFAQTQAQNLTACAGQTVLLGHSSGGWAAYTIVSALCAQGTPPAGLILLDT
PAPGTPSPEQTTAVLRHLMAQPDDAANDDYGLTTSGAYLALFDGWNPPPLPLTTLLVKAT
TPLPDTDAPLPPWPTADTVRETAADHFSLLREDAPATATVINEWLEHLP
>B8MLT4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MLIFTPTTTSDSDLDSRKMKLVYFSNEFPRDDLQNFNDKHHSHLAQFICEATWAIKEEAR
NLPTELKKLIPPFKTLVSWSENTEIREGLICGAVDGVLLVVVQIATYIGYAENSPEELTD
FPNLNLAGLGIGLLASTAVSLSSTLADLPLAGADAVRLAFRLGIHVLDVSENLEARDLSE
SPDTWAYVVHNIDPDIVRKELDTLYLRDEIPGTGKIFVSAVSRTSVTVSGPPARLKALFN
KSDFFRESTFIALPVYGGLCHAPHIYDMHDTQSIVDQNSLLTVRTKSWPGAPIYSTSTSV
TYPAKKDTELFESVISEILTQAIYWDRVISGVVERVKTTVTSEVALYSFGNSIPLNDLNS
ALKSSITHSNVSISNLTTFVTQVAPKDTTPRSTSQSKLAIVGMSCRLPGGATNTEKGLDV
SRKIPADRFDIETHYDPAEKELNKTMTQYGCFIGEPGLFDAPFFNISPRESQVTDSQMRL
VLITAYEALERAGYIGNCTASTQLQRIGTFYGQAADDYREINQGQEVSTYYIPGGCGVLG
PGRINYFFKFAGPSYSIDTACSSGLAAIEVTCQALWNGEVDTAVTGGVNVLTNPDGFSGL
CNGHFLTKGYNACKTWDTTTDGYCRADGIGSLAIKRLEDAEADNDNILGVILGAGTNHSA
EAVSITHPHAGHQAYLSRQVLRQAGVDPLDVSYIEIHGTGIQAGDHEEMQGIMDVYAPLT
RRRSKDQPLKYWRRKSKSLIKVLLMLQKNAVPPHIGIKTEINPKFEIDPRKTHIIAISAK
VKTSLTGNIDRLIGYLDSHPNTNSADLSYTTTARRYHHTHRVAIATSDVAHLKRQLSSSL
DKVDLINPVGMSGPPLVAFSFTGQGASYKSMSLELYRGVPTFRKHIQYLESLGQGQGFPS
FIAALDASYPNEHAHSAVITQLALVCTEIALAKHWATLGVKPDVVLGHSLGEYAAIHTAG
VITASDAIFMVGRRAQMLEEKCKVGSYIMMAVRASVAEIVES
>A0A378BHL6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Klebsiella pneumoniae subsp. ozaenae|TrEMBL
MLGQALTDNGDYLADWSDCAGQPERFNARWQEAWRLLSQRHGDALPVEPPPVAAPEWLGK
VRLSWQNEAFSRGQMRVEARHPAGEWLPLSPAAPLPAPQTHYQWRWTPLNVASIDQPLTF
SFSAGTLARSDELAQYGIIHDPHASSRLMIVEESEDTLALAEKVIAALTASAAGLIVVTR
RAWRVEENEALSASHHALWALLRVAANEQPERLLAAIDLAENTPWETLHQGLSAVSLSQR
WLAARGDTLWLPSLAPNTGCAAELPANVFTGDSRWHLVTGAFGGLGRLAVNWLREKGARR
IALLAPRVDESWLRDVEGGQTRVCRCDVGDAGQLATVLDDLAANGGIAGAIHAAGVLADA
PLQELDDHQLAAVFAVKAQAASQLLQTLRNHDGRYLILYSSAAATLGAPGQSAHALACGY
LDGLAQQFSTLDAPKTLSVAWGAWGESGRAATPEMLATLASRGMGALSDAEGCWHLEQAV
MRGAPWRLAMRVFTDKMPPLQQALFNISATEKAATPVIPPADDNAFNGSLSDETAVMAWL
KKRIAVQLRLSDPASLHPNQDLLQLGMDSLLFHELSSDIQHYLGVRINAERAWQDLSPHG
LTQLICSKPEATPAASQPEVLRHDADERYAPFPLTPIQHAYWLGRTHLIGYGGVACHVLF
EWDKRHDEFNLAILEKAWNQLIARHDMLRMVVDADGQQRILATTPEYHIPRDDLRALSPE
EQRIALEKRRHELSYRVLPADQWPIFELVVSEIDDLPLPVCI
>A0A377K6R0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Escherichia coli|TrEMBL
MLAAIDLAENTPWETLHQGLSAVSLSQRWLAARGDTLWLPSLSPNTGCAAELPANVFTGD
SRWHLVTGAFGGLGRLAVNWLREKGARRIALLAPRVDESWLRDVEGGQTRVCRCDVGDAG
QLATVLDDLAANGGIAGAIHAAGVLADAPLQELDDHQLAAVFAVKAQAASQLLQTLRNHD
GRYLILYSSAAATLGAPGQSAHALACGYLDGLAQQFSTLDAPKTLSVAWGAWGESGRAAT
PEMLATLASRGMGALSDAEGCWHLEQAVMRGAPWRLAMRVFTDKMPPLQQALFNISATEK
AATPVIPPADDNAFNGSLSDETAVMAWLKKRIAVQLRLSDPASLHPNQDLLQLGMDSLLF
LNSVAIFSTTWAYASMRNGRGRICLLMDSRSLSVLSQRRRLPLRSRKCCGTTPTSVMRPS
L
>G0PUK8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MHALSSRRLITRAPAVFKIILPSKANDGPVEHDMTLLDVLLDAVREAPGQVVVHVRGDGG
ELTVSLSELLDESLRVAGGLRAAGVAPGTCVPLLADRSEDFQPMFWGAVAAGLVPVPLAP
DARRVLPVWEHLGRPPVVVDASTASLSGELPDDVRALSLDVLREGPALREPVAAGRDDVA
FVQFSSGSTGAPKGVEVTHGAVLANLEQIRAASELGPEDVVVSWMPYFHDMGLIGTHLAP
LAARARQVKIGPLSFAKRPRLWFEVAARHRATVLSAANFALALAVRRVPEEVLARLDLSA
VRLVLVGAEPIAPAVWRAFADRTRPSGLAPAAAQPVYGLAEATLAVTFPPPGEVAEPLVL
DRASLSRGVAVDAEPGNEAVELMDVGRPVAGCAVRIVDDAGTVLGDRRTGHIMVSGPQLA
RGYHGLPDVSAEVFAGGWLRTGDTGFLRDGRLCVTGRHKDVLFLNGRTFHATDLEEVAAA
TPGLPSGAPAVVGSTDPVTGAERVVVFVPWARPAREASEVLERVAARVREALLHDDVRVL
ALPPGAFPRTTSGKLQRRRLRERFEEGVFGSGERPAVEPGAGEVAAGAAGGPPFAEPGRP
AAEPRALAPRTRAETVEVVREAWARVLGRPADAIGTHEPFGSIGGTSLKAMEMLVALEDA
FGVTLPPAVARDHDTVAALAGHLLTVAPGPVLPLADSAKASDTSETSESVVRRTGGTAGG
RAPALPVPADAATAVIGMACRFPGADTPEAFWDLLVDGHDAVAPVPRGRWDDGHAAPGAR
TAVPGVAGVPGVPRERWAALLEDPAAFDADFFGIGEDEARTLDPQARIFLELAHEALERA
GYAGPRRRGRRIGVFAAVGDSGYREVLERARAEGAPLPAALTGNLPSLVAARVSQCLDLD
GPALAVDTACSSGLVALHLARRSLLDGECDLAVVGGVNLHLTSAPHRLLEEAGALSPTGR
SRAFSSDADGFVPGEGGAAIVLTRLDAARRADDPLLAVVRGTAVNNDGRSMSLMAPNPLR
QREVITRAYEAAGVDPAAVTYVEAHGTGTAVGDPIELRSLAHAFPERPGGEPRLVGSVKT
NIGHLLNAAALPSLVKVVLALGHRRLPPSLHHTPASPGLAPAGFSVVTKARDWTSTGPLL
AGINAFGFGGTNAHAVLEQAPPPAAPASPPTSEAREVSVEGPHLLTLSAHSPGALRDAVT
RLATHLESRQLLREGDVCRTASISRDEGPHRLAVIAHGDLRERLAAVSAAGTGEAGGRGG
SPVRSRPRVVFLYPGQGSRFPGQDRALYRTARVFRDTFDEASALLGPVGGRSLLDWALDP
EVDAAARDATEQAQPLLVASGVALSRQLRAWGVEPDAVAGHSVGELTAACVSGVLTLREA
VSFAAERGRLMEAFTEPGAMIAVRGGEEAVAAAVAESDGALTVAAYNGPGLQVLSGGVRA
VESAAARLEGLGVPTRRLRVSRAFHSPLMRPVADRIAEAARALAPRAPSVPLMSTVTAEW
QPVLGPEYLRDHAERPVLFGAAVERLAREGYDTFVEVGHGATLSGAVRAATGVAAPAGVG
EAGASGAAGRPATVLCALPGRSESRADAERRSSEDGHGGPGDLLATIGRLWSHGVPLDRT
ALDAEHRAIPLPTYPYQRRRYWADPPASPLLHRVLWEDSALPGQTARAVRSVLLTGPDPA
YVAGLASQLADAGVRTHETDDGPPDAVVLVAGPAPGQDTADALGRAQGTALAAFDEALAR
FDETGADRLLVLTEDVHATGAVRERPRPAHAVLGGLLMALPQETSGASATALDLCSLDTP
SQRLAAVLAELAEPAASSGPRGGAALVARRAGRRLTRRFAPLPSGAAAPAGPGRSPLPPD
GTYLITGGGGGIGASLARDLAGRGRPTLVLAGRSPGLPEGLSEELRALGATVDYRMADVS
VEQDVEALLAGLGHLDGLFHAAGAVRPGTLRDRRAEETAEALAAKTRGTLLLSLALRRHG
LDPAVRVVFSSVSAVLPGLAGALGDYAGANAFLDAFAASERHAGRPWQSVNLAAVAGTGM
AAALGTGAWPATGGGPAAVESAGGRPVALRPALAALRTACGVDAAQLLLADLTPFREPTV
MTDRTAPAADAGPGDSPASGTDSSGTVYGTAQPPGAGRAPGAGPHTGTRTGSGPRTDTAG
GTAALLRRLLASALRLPDAAVPDDEPFLALGLDSLAAVDLVRQLERELGRTLPATLFFEY
RTVAELAAHLDTTPSLLRSPASAPPAVPDGVAFPLTPVQLALHTSSRLHPDVPAHGYVRQ
TVRGPLDTGLLGRALTALADRHAMLRIRVQQTGSLGSGDDGTSGGTGSATPGQYVAPPAP
LSAWYEVREPAGRIEEVETALCNRPFDLSAEPPVRALLARESPELSHLVLVIHHAAGDGY
SLNVLAGELWSLYTSLAEGQAPTLPALATDFARYAVATAEARSATDGTRALAADRLYWSG
RLAARGEPLRLPYDGDPCALPAAPVNTHQSALGPVPTAALERRAAAHGVSLFHLLLAVHV
RCLARWSGQREIAVNVARARRDDRMAGLDRLVGPLADTLPLLCATDPDEPVETLAERLAG
IWLESERHASLTGLDLARLLPTDPSGAGPRTVSPAGFSFSRFPAALDGRCPVSVRPTAAG
TATAATRLSLLCWQDEAVLRFSWNFPARLFAPATVARLDRDFHAELTALVEPRPGLPAVP
GPVQVPAPGTGSATLVRRLVERFRTTPDAVAVDTGTTTLTYAELDRASHALAASLLARGV
TGGSLVGLLTEPGADTVVAVVAVLRAGAGWVPLDPGHPTARLTDQLTRSGARTVVCHAAT
RAVGEALGDVALVDADVSALAYRGAGVPGSVPGPDRVAGTLRSPEAAPAPDGPADADAIA
YVIFTSGSTGRPKAVPITHRSMENYLDWAIGTFGYDEHDRLAQTASPCFDASVRQLLAPL
LVGATVVTVAWDLLRDPDRLLTHVVRGRITVWSSVPTLWEQLLSASEERVRNGAPPPDLS
ALRWIHVGGEALSPAHVRRWFDLFGDGQHIANLYGPTEATINTSCHIIRARPGDQVRRLP
IGRPVAGTEVEVVGPDGEPAGPGEAGELLISGVGLTPGYLGEPALTEAAFTVRRGRRWYR
SGDRVRCSEDGVLEFLGRLDDQVKIRGNRVEPGEIEAVLQTHPDVAHAVVLAEDGRLTAF
VTPGPGAAGADAAGLRLHLAQSLPAYMLPSRITRVDRMPLTGTGKIDRRALPALQEAAAP
PGADTNAGPAARTGDVRTPPRTPTEVRLAAIWTALLQTDDVSREDDFFVLGGDSLLVLEV
FARLEKQGGPLPRPTVLYRNRTLAALAAAVDVAAGAAAESGEPTAVAARAAADPSAGEPG
AGDDRTGAPDPSVTPLPFPLTPTQRGFLLAEALAPGATSSWLTRLRLHGRLDTARFQSAV
DTLVERHPMLRTVFPAGARPAVQQELPSSLRLPVDFEVLTDPAHVEERVTAERARRFEPW
AWPLMRLRVLTTAPDEHVLVAHAHHIIGDGYSAALLVRELTAVYDALSRGEEPASGRPRS
TFRDHALHLAARTDARTAPPAATASGTTAGRDSVAPAKSPRPGVPAVQDRWERLNAPYAQ
PRLAAGTTTAGAPRDAAAPLFHTCGFTVEADRVEALRGLAARTGSTLHAPVLTAYYRALV
SATGRADLVLGMAVSGRDHALPDAHRVFGPFATAVPLRPAGPASGRPGSADFDDDLRRVA
AEAAEARTYEGPVPPLSNGLPMTSQFFFTYLDFSALGPEVGRTLTVTREGGDSVYTPPPA
GTDVFLAAAPEGGRLRITVRAAATAFTPKALAAFTDSVRDGLARTAASTAAEAARPDRPA
SGRDGRMDAALVGYLPSPADLARLAGLPETALPREQLRTLLFPDGLPRLLETLRTPLGRS
GFVCVPLFADELAPGDDLLGHTTRGVELASSLGARAVSLAGMIPSLTGYGFDVLRAVGTT
EAVTTTGPAVTTGHAATVVSVVRTVHAALDATGQRLGSLTVAFVGLGSIGSSSLELLLTR
SQQPPARLLLCDVPGSGPRLKELAESLLERSLVEVVEVVESGHGLPDAVYDARLIVAAVS
GGGALLDIDRLAPGTTVVDDSFPHCFDTSRAVGRMERSKDVLVVGGGLLSAGPAERRVAE
GLPAAAVAGYLARPMVPDTIASCRLESLLHASGAGVPLVHGPVDAATGLAYWEAAEATGI
RAAPLHLLTRTVDPDMFTRHPWSS
>G0PUE4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MNTFEHASSNAVAVVGLSCRLPGAPDTPSFWRLLSSGTSAITESSRFGDAVPVRWGGFLP
DDEVGAFDAEFFGISPKEAAAMDPQQRLLLELGWEALEDAGYVPAELRGEHLGVFVGSMA
SDYATIAARAGVVSRHSLTGLNRGLLANRLSYVLGLRGPSLAVDTGQSSSLVAVHLACQS
LRSGESEVALAAGVNLILTPQSTVEADRFGALSADGRSFTFDARANGYVRGEGGAVLVLK
GLAAARRDGDTVYAVIRGSAVNNDGPAATLTTPSRSAQEAVITAAHRRAGTAPDEVGYVE
LHGTGTPVGDPIEANALGATLGRERTEPLRVGSVKTNIGHLEGAAGIAGLLKTVLSLHHG
AVPPSLNFATPNPDVPLEELNLSVQQELEEVGPTVAGVSSFGVGGTNCHVVLTGTERSPR
EPRPAAAGGPLPWVLSARTEQGLRDQAGRLYERVAAPDAPASDDIAFSLATSRTHFPYRA
AVLSGDAEGLLGLRDGGLSADLVRGRAVPSGGTVLVFPGQGSQWAGMAAELIATAPVFAA
KIHACAEVIDPLVGWSLVDVLREEPGSPSLERDDVVQPALFAVMVAFAALWQAAGVRPDA
VIGHSQGEMAAAHVAGALSLRDAATLVVRRAQQVVRIPRAGGLLSVPLPVAKVREDIAAW
PDRLGIGAVNGPSATIVSGELDALRELESAYVADGVKARVVPINYASHSPLVEDIREDVL
RAAADVEPLRTDVAFYSTVTGALLPDTSVLDAEYWYGNLRQAVEFERAVRAAFADGHTTF
VECSAHPVLGVGITQILEGREAVITGTLRRDRGGLRQFLSSLAGVHVGGGAVDWAAADWE
GLLAGRPVRRVALPSYAFQRERQWLDVGADGVVPSVPGPRPTPEQAPADGGQRPGSGGDL
TPERALDLVRGAVAVVLGHASPASVPVDATFKELGLDSIGAVEFGRALAGATGRPTTSTL
TYDHPTPASVAAYLTRGDAEEEFTAAGASDEPIAIVSASGRWPGGADTPERLWQIAVDGV
DTVGPFPSNRGWDLEALYSPDEPRTGTSYTDRGAFLYGADEFDGAFFGLGPREATAMDPQ
QRLLLESAWEAVERAGIEPGSLRGSPTGVFIGVMPQEYGTRLHQTTEEYDGHALTGGLTA
VASGRLSYVLGLEGPAISVDTACSASLVSMHLAVQSLRRGECDLALAGGVTVMSTPGMFT
EFSRQRGLARDGRCKPFSDAADGTAWGEAAGVVMLERLSDAVRNGHPVLALVRGSAINQD
GASNGLTAPNGPSQERVIRASLADAGLRPSDVDAVEAHGTGTTLGDPIEAQALLATYGRE
RDVPLLLGSVKSNIGHTQAAAGVTGVIKMVHALRNGVLPATLHVDEVSRHVDWSPGTVSV
LTRNTPWPETGRPRRAAVSSFGISGTNAHLILEQAPKAAPASGAVEGAGAAEAAVSAEAV
TGPAVVPWVLSAGSVAALREQAARLHERVLGDPGAGVEDIAASLTRTRSSFDHRAVVVGA
REQLLDGLLAVRDDEEESAAVVRGTVAPRGRTVFVFPGQGAQWAGMGRELLATSPVFARA
IERCAEGLAPHIDWSLTDVLRGEPDSASLERVDVVQPALWAMNVALAELWKSAGVRPDAV
IGHSQGEIAAAVVAGALSVEDGARTVALRSRAIKQIEGGGGMASVPLPADAVRERLMRWG
ARLDVAAINGPSATIVSGDADALREMVDACRADGVSAKTIPVSYASHSSHVEAVRDDLAR
ALKDVEPRATGLTFFSTVTTRPLDTTLLNADYWYENLRETVRFEDTVRAALADGCTTFVE
ISPHPVVAVGLNQITDEAVITGTLRRDKGGLDQFYAALARVHVTGVTVAWENVVSGRTVE
LPTYPFQRRRFWLDAPATTGDVGAAGLEEAGHPLLGATVELAGDGGLVLTGRVSLGVHRW
LADHAVFGRPLLPGTGFLELALHAAGRVGAASVDELTLEAPLLLTEDGAAQIQVVAGPAD
EDGQRTVGVYSREAGGEWTRNAHGTLATAPDGEPAVREERLSGTWPPPDATTVDVEELYD
RLSAQGYDYGPAFRGLRAVWQRGEEIFAEVALDEDAPGAEEFGLHPALLDAMLHPVVGIA
VTGPQVRLPFSWNGVRLYAPGATELRVRISPAGQDAVTITAATEGGLPVAHVDSLRLLPV
SADQLGGARTAPPYRLTWSETAVTRAPEPAVAVTDIETGFAELADVPEFVVLDVASRAPG
SVVAETHRVTARVTELLREWLADERFTASTLVLRTRHAVATGAPADADAVADLVAAPVWG
LVRTAQAEHPDRLVLLDADGDLDAGLLAGAVASGEAQFAIRDGSVLVPRLAQLTPGALAG
AVPALDPEGTVLITGGTGGLGGLVAKHLVTRHAVRHLVLTSRRGADAPGARELADELVAL
GARVRLAACDAAEADDLAALLATVPPEHPLTAVVHTAGVIADGTVASLSAERVHSVLRPK
VDAAWNLHELTSGLDLSAFVLFSSAVGVVGNPGQANYGAANGFLDVLAHHRHAQGLPAVS
AAWGLWAEASGMTSHMTATDVERIGQRGLRPMPTEVGLAHFDAALSAGLPALVTARIETR
DVDTGSIPVLKGLAGSGPKRNAPKRSLAAELVGLDAAEQHALLLDAVLRTAAGTLGHDSA
DAITAHGGFLEQGFDSLSAVELRTRLGRLVDTKLPSTLTFDYPTPDAIAGHLRSLLVRDG
TESAPDVLGELDRLRALLSATDAEALEKDRVAVVAALNELMGLVDVEYAIDTQRSDEDFF
AMIDNELA
>A0A3N6HNW2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI96-02|TrEMBL
MHMMDCVFVMPGTVAAPRGGVLRDFHNRYESVRESLSLIDTAAREMGLPDISSRLIEHDG
TTDRRGPEVQYLEIFAVSIATHHVLIAEGVRPVAIVGQSIGELWALAAAGRLSVDDAARL
AVARSRALTRQNWGGKMLAVGVDGRRAESLAGLINHPDLVLACENTPRQSVISGPEPLIE
QVERVADALGWPSFRLDVPHPTHTPAMAQASRDLRATAPRVAYGAGRWRVCSPWLGRDVG
DDDPVGLVADALTARVRILRTIRDLHAAGADVFVECGEWPVVTKFVEASVPGVRCVVPLS
GSDPVAAVRELVTGSTDGGPFLPRPPAPSGTERGPAVRVSAATASAPVPALLTAAPLSGT
TNVSASAPSMSYVATRPAPAPATPAAPEAPAAPASTPVAPVAPVAPPASAEWDYETVLAE
LRTLYGDFLGYPPDLLGEDDGLESELGVESLKQVALLGRVSERFGLPGLRANSSLLTVGT
LRRIAESVVQGRAEAAAR
>G2E5C9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Thiorhodococcus drewsii AZ1|TrEMBL
MLKPISFPDLRSAFLADGASSGILTRIAGDGSETVLSPAGLREAADRIARQLDHGGIGPG
AYVMLVMRDPLAYVTGLWGCIAAGCTAVPMPPLDNPTQQQRTLAAAGVIGRCIVLTDEED
ARSSFEGTEAIDRAYRLIGERFDRIAELDETPSATSQVAPPIHPDDIAIIQFSSGSTAAP
KGVELTHRAVLAQIDVLQRHLALTADDSFLSWMPLSHDFGLFHFHILPLLVDLPQVLMAP
DDFARRPISWLRAMDKHRTRLTGAPNFALQMVASLLKPKSAAQLDLSALRSITNGAEPLN
PATIAVFLDALAPSGLSRTAITPAYGLAEATLVTAIRTPGEPLAVIAVDRDHLTIGAEIV
EHEPDAPNTAHLCLLGRAAYGFAMRIVDESGTPLPSGTVGRLEVRGSSLMRGYINDPEHS
RAALHEDGWLDTGDIGFLWQEELVLVGRHKDVIIVAGLNYHPADLERVAQEAPGLSAANP
VAIVQARCPHSDEIRTLCFVRFRGTPEKAERLQTAIADHVLAKSGLALDQVVPVHQLPRT
TSGKLKRYELGQHFEAGALGAETADRVRETQTEAAAFRQAIAGGHISEVTRLLCRLASHL
SGTPIEPESGLMDQGVSSQQALALTARIGTWLNRRVNIAVLFDHPTPRGFARALIAQHAE
ISPAPAQVVSAQETTACSIAVIGLGCRFPGAENPEAFWDLLIGDRNPIRPIPEDRWPASA
WPEEAPCPPAALLDDIDRFDGTLFGIARGESEGMQPLQRLLLQVLWQALEHSGLDPAALR
GQRVGLFIGLSESGLGAGDRRLMDDAERLGAYSVTGHAGSVAVGRMAHLLDFRGPAIAID
TACSSSLVALDMAAHSLRQGACDLAIAGGANLIISPELHAGLSRMGVLAPDGRCKTFAEE
ADGYGRGEGAGLLVLKRLAEARRSQDQIWAEILGSAVNHDGQSQSVTAPNGTAQRDLLRR
ALREAGLDGKDVDWVETHGTGTPLGDPIELAALHEVLRPESQAPLPLGAVKSRIGHLEAA
AGIAGVIKAILAMTHGRLPRNRPRKAPSSRYDWSTSPLTPLDQTLDWDDAKRRVAGISSF
GMSGTNVHVLIGQGQVSEAVAPMPNRTPILALSAHTPEALQQLHDRWSALLSERPAEHWP
SLCAGQATRRWSGPYRMAVTRLDAGRGSSHPPVVKAKTVTRLLFCFTGQGAQFPSMGAEL
FAQEPLFRDAVIAASEAAGPIDGKDLLAWLYGPDAADAARMNRTDLAQPALVAVAHGLMR
LWADWGIQPDAVIGHSIGEIPAALAAGQLDLQTAMRLAVRRGQVMEHAAPEGAMLALRAD
EERALELLRGFDEVVISGYNAPGSLTLAGSVEQIESLLARAEEAGLAAQRLHVTRAFHSP
QMSQASAELANGLSLPERAGVIPVYSTATGALLGDSEMTQPGYWSSQMLSPVRFRQAVAT
AAESGDLICIEIGPRAVLAKLGPACAPDATWIGGGDRLEDLAHAVGQAWTHGAPLDWLRY
FGSRGAPGQDLPRLPLNETPIPRRTWSGAVVAPNAPSVPRTTTAASDAPPPSGHALDAIV
LPLTSRVSGIETDRIDPDRPMVALGLDSLGLVQIQRSLAKSCGLQIELKALFQTLDTPRK
LADHIDAQRPQPAPPPTATAAPDSAHPSPEVVALMQEQLRTLQQVMERQLTLLGAPASAP
SESAGPAKTSPVQTLVQTPARPHARKPNTGEIKGLFRQPSRSGVGLDPGQRTHVARLTRS
WNTKSAGSKAGAERARKRVANSRAVFGFAPEYKELTYPLMASRAQGSQVWDLDGNAYVDV
TMGFGVYLFGHNPDFVAHALREELDRGAPLGPTSPLAAEVAERIHQLTGVDRCAFFATGT
EAIMCAVRIARALTRRDRIVVFKGDYHGSFDGVLATGWIDEDGSPQSAPLTDGTPQGMVD
PVIVLDYGDMSGLDLIRRHASEIALVLVEPVQSRNPENRPIEFLQALRALTQERDIPLLF
DEIISGFRFAPGGMQSMLGIKADLVTYGKVLGCGQPIGVLAGDARLMDAIDGGDWAYGDD
SGPGTRTAFVAGTFNAHPLGLAAARAVLDRLIADGGALQQDLARRTENLCATLDALFETA
AMPVRMERFGSLFRFAFGPGMEILNSHLLNGGIFVWEQRNCFLSTAHSDDDIAKIVEATR
RGIAALQAAGWLGQSQRQDQTESARPSRLQPAISETTMRRHAGTAHPGTWTDLVILRLSV
DRLDPDRLTTAWSALCRRHAALRACLAADGTRCVADGMAPALERTQLPEKPEFRIGLDRW
AQSALAKPFRLDRAPIEPVLLETAAGEQALAVRSSHLGFDGWSVALLLRELFQLIDDTPL
PEADRWNAYLGWEAQAEFTRASMQARPMHLPCDVEPASMTAAGGRITRTDIGTLFARVSE
TARSGGQTPLVGMLAAFALLIRGLTGEERVTIGLPVAGQALSGLTGLVGNVSFIRPVTLD
IADAMTLAELRRTLHHRLLEPGAHPPADAMPERHVLFNIDGPIRFGGASRQVALHSVPIV
GARADLFANILLLDDQVILDFDWNSDRFSEDSAQSWLATFLEIAERSCADRAAVAQILAD
RAWPAPPATPVQRKAPRAEKPAHPSTATEQTLADLWREILDTGTDLGSSDFFDLGGGSLH
AVRLLARIRETFGVELSLAQIFGAPLLEDMARQIETAATADGGIDPVRPIPAQVPATRQQ
QQLCLLEQMSEAGPAYNLCLRLDFDYPLDAQTLGGALRRVGARHTSLRTRLCMDGESIVQ
SIASEPDISLRTLDASTAEWIAPFVQEPFDLAESPLWRAGLAFPGDGCTLVLVVHHLIAD
AWSMEILARDLLGAYQQILAGQDPGLMPLAIDYSDYALARALGTEHRERDLEHWRTSLRH
APRLTALAGDAPRPPTKSFAGQQTRLTLAPALQQRMRGLAKRLRTSVYQLVVAAIAQLVA
RRNGSGNLVFGCVVAGRDLPGLDRPIGFFANTLPLHLVLHEDWRAVDLIAAVRSALMDAT
EHSGCSLQDICTALQLTPDPAANPLFEICVTHDDRSGLSQLGAELGFAFAEPPLPTSQFD
LSFYVVETGDGVSLDLTYATAIFQPHTITGILDEIERMLQALCHDPEAPIASWSRTDQLR
EPSALQKRLWFVDQFENGQLYATAPTYYNMAATFALDANADPALLQQRFEQLLADTPDFR
ATFRTLDGNPRISAASIQVPSCTAICGDEIDAQVRRFILTPFDLQTGPLLRMAVVEHAPA
RRALLLVGHHIIVDEASLAGIADWLRVGTEIPKQAAPGQSPVPDASVLQLERDFWQRYLG
PNPPRLLLPVDRPRAAVHVFGSGLSQVSLTAAEFAAIERLAADSHVVLDDLILTGFVGLL
SRLSGQEEIVLGQTVPRRSGYPRGQANLVTLRIDLTRLSDTTEAIAEVARHSTETLAHAQ
TDFDQVVLDLKPDNDMSRTALFDVLYVRSAEPVAGRGMAPAIGWGKYDLTLAANHAGDGR
LDLMLVFNSEMFDAETVDHWGRLLCRLLAALCAHGDRHFLSLPLATGTEIDQLIADGGPR
RTQATWPYANLPDAVSDRARRMPDMIAVSDATGTLTYADLELQARALAQALIARGVLRGD
RVALMLPRDRDTVVAMLAVLCAGAAFVPMDLSAAPERTARILQDAGAVSVIVKGAMGRDL
LPLDLPRVDMTRLAEDRSGAEPEWPEVRATDGAYVIFTSGSSGRPKGVMVEHRNVLALML
GQEDLFPVAPGDRWSWFHSPAFDFSIWEIWGALLTGGRIVVIPEAARDDFALLRAQLKQQ
EVTVLSLTPSAFNVLSDQEMNEAQADLAVRSLWLGGEALTPTLLRAWSDRYPDCALINLF
GITETTVHTTFRRLAKTDLDRTDSLIGRPLPSYGVTIRDAELRPVPATVQGEILVSGSGV
ARGYLGHPELTAARFVEDPYRPGSRLYRSGDLGRYDLAGELTYLGRADSQVKVRGFRIEL
GEIETALSGFPGMRKTVVGTRQSAGEETALAAWIIADAEPDADRLNAYLAKVLPAYMIPK
HLYRVDHIPLTLNGKADLRALAGMCERQIGAASEDDAPSPGLETEIAVILCELLGRTEMS
RSASFFALGGHSLMANQAVLRLRKRLGLQLTLRDFFTAQTIAALAVLGQDGRNTATTGIA
RIPDADSYPLSSAQRRLFAIQTAHPDSASYNMVGGFIVSGALDPDALAAAFADLVDRHEI
LRTRFLILDGEARQRIDPPGRTVALDLIRNADAADEQAIIDRALDAEFAHAFTLSQGPLF
RVRLTALGPERWLMVLNLHHIISDGWSVPIMIADLSRCYAARAAGSGPPQLKPLAIQYRD
FASWQQTACANPEAEAALAHWRARLASDAPLQTTLPTDSARTKTRAGRGAMALRRLDEER
SRALRTAAAQSGLTLFSVFAATLHIVLELRGESGGATVIGTADAGRDALETEDQLGFYLN
LLPHVLSGSADLSIERWVELSRAETVAMLAHKTYPFDRMLEELAIDTLPGHSPVFDILLL
VQTNADPQTRLGDLELRMLPDQTRTARYDLSLMVEDRPAIELLIEYDTDLFRAQTIDWVF
ADLLSLLDAFVDSPSLSPLAILGQTEPAMDPSLGLLDLADPLMEV
>A0A5S9RA86|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium vanbaalenii|TrEMBL
MVSSRLPDGRVAVLLSAHDEGLLAFDATALGDYLDRHRCDVAQIAAQLTATRRVRRHRAV
VRANDHDELAAGLRAVAAGQPHSLVERGERRAATRTAFVFPGQGSQWPGMGADAYRSVPR
YRAEADRLDAAFLAAGLPSPLAFLTIDTETAAVSQLELQGAQFIHAVALATVWRACGIVP
DLTIGHSLGEIAAAYVAEVITLRDAISVVAARAHAIESIPGRHGVAVLGVDPARAAELID
ATAGWLELSAVNAPESVAVAGEKDAVGSVAAAATARGLFARELAMSFPAHTSAMDAQRDE
LLRRLPPARFGDSAVQFIGSATGAVVAAGTEFGPYWYANLRNTIRFDRAVQAAIAGGAGI
FVEMSAHPSLLFAVEDATERGADAVGDPAVVVGSGHRDRPLADQLAANIVAAAIADPGYR
WADLLDGRPEPLRGFPGAPMRSEHLWARAEPLPPAPAPTVTAERWQQHPTRPQPTGTTRS
VAVLGLQADCPLTAALRDAVESHSGAVLTDAADADVLLAVAFPPAPTDIVGVVRDLADRI
DTGLLGYVDAFGPRCRDVWLVTAGAERVTATDPVPDPGQAALAAMHRSLGFEFADQSFHH
LDLPAQNPASLLAEVVSAALGEAGEMAVRHQPSGPSVFRRTLGQDAASAPFRPLDPAVFE
RVVITGGSGAIGLSFARALAGRGAKRVVLLSRGGGEPAVLADLCARHDVEIVAPRCDITD
PDQLAAAAAEHAGGAATLVIHAAGTATFADHSGITGRSLVDLSAAKLGGLQRLTEVWPIA
ADARIMLCSSVTGVWGGKGVAAYAAANRMLDVMAARLRADGRNCVAVRWGLWEGSGIVDA
AEIARVERSGLRQMTPALAVEAGLQDYQEDPLVLAADPLRLQMFFGESDTELREVTAPSA
ASDEEATTGPAVVRGQLAAVLGVEAALLDLDSSLFDLGVDSLLALDLRKRLKRLTGQTVP
LARLLGGITGTDLIAELSEKVDSSRD
>A0A1Y2NI30|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces platensis|TrEMBL
MENEAKLRDYLKRATADLRRTRQRLREVEEKQHEPIAIIGMACRYPGGVSSPEELWQLVA
DGRDAVTTFPDNRGWDLESLHDPDSGRPYTSYVREGGFLHDALEFDPEMFGISPHEASAM
DPQQRLLLEASWEAFEHAGIDPMALRGSSTGVFAGLMYHEYASRLNHVAPEAAGFLGTGS
IGSVLSGRISYSFGLEGPAVTVDTACSSSLVTLHLAVQALRTGECSLALAGGVTVMSTPD
TFIDFSRQQNLARNGRCKAFASGADGTTLAEGAGMLLVERLSDAERNGHPILAVVRGTAV
NQDGASNGLTAPNGPSQQRVVEQALANARLSADQVDAVEAHGTGTALGDPIEAQALLATY
GQGRPEDRPLWLGSVKSNLGHTQAAAGVAGVMKMVLAMRHGVLPKTLHVDEPSSHVDWSA
GAVELLTEARDWPEGEQPRRAGVSSFGISGTNAHVVLEQAPVAEPAAVASVEGAPVGVVP
WVLSARSEQALVAQAGRLASFVADRPGLDPADVGFSLLSTRAGLEYRAVVLGADGEGLLD
GLRGLAAGVDPAGVVRGATGTGAGSRVALVFPGQGSQWLGMADELLASSPVFAGRMAECG
AALSEFVSWKLDEVLSDEDMLARVDVVQPVLWAVMVSLAAVWEDCGVVPSAVVGHSQGEI
AAACVAGVLSLRDGARAVALRSQAIGRVLAGRGGMVSVAASREAVQERIAKWGERVSVAA
INGPTSTVVSGEPDALQELLAECAEQEVRARQIPVDYASHGAQVEELREELATVLAEVTP
VEGRIPFYSAVNAAPISGEDLNAAYWFENLRNPVRFEEAIQALLADGHGVFVECSAHPVL
TPGIEDTAQQESGSPVVVTGTLRRDEGGWPRFAHSLAQLWAHGVPVDWSTLLPAGRRIDL
PTYAFQRQRYWLDDTGAVGDVTAAGLSSADHPLLGAAVSMPGTQVLTGRLSQATHPWLAE
RIVLNTVVVPETAFVDLAIRAGDLVGCDLVRELTVETPLVLPDRGAVLLRVLVAEPDADD
GGREISVYSRPEDVPDEQAWTRHATGVLVRSAEPAGFDARIWPPTDAEPVELADFYRERA
ELGLGYGPVFQGLRAAWRRGGELFAEVALPEGDTGDTSGFGLHPALLDAALHCAGPEGAQ
LPLAWTGVSLHAVGATALRVALTPAGDGYAVRIADVEGAPVASIASVTWDDVAAERLAEG
AGRSESLYGVDWVAPTPTAPPTPTPTLTPVPVDPEGSSLVVLGGDGLGGAAVPGADVMDL
EALKALDPTPEVVVLPVPDSGVVGVSGGVREVAYGVLETLRAWLAEERFAGSRLVILTRG
AVSVTGEEVDLVTAPVWGLVRSAQSENPDHFVLVDSDERQVSRTALAAAVALGEPQVVIR
GGELAVPRLTTLEPAENDGGPVWKPEGTVLITGGTGTLGTLVARHLVTEHQVRNLLLTSR
RGPDADGADALRDELTALGARVTIAGCDTADRDALAGLLAGIPAEAPLTGVVHTAGVLDD
GVLGSLTRERIDAVLRPKVDAAWNLHELTKDLDLSAFVLFSSAAGVFGAPGQGNYATANA
FLDALAAYRRAHALPAESLAWGLWEESSGLTGTLSEADRQRKARDGLRPMSSAEALALFD
ASVAGGRALTVPVRLDLTALGAGLRTDEVPPLLRRLVRGTRRSAAAGQGGAAGLPERLKT
ASPAQRSRLLLNLVRGHVVAVLGYADADAVEAGKAFKDLGFDSLTAVELRNRLNRDTGLK
LPATTIFDYPNSRVLAEYLGTHFAPYGDAGSGADDNEETIRRMLTSIPLNRLAEAGLMSS
LLELAGITEEASETTEDDDRESLDTMDMEAMIQLALDGSGAEDDMTRGL
>A0A0N1H052|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OV450|TrEMBL
MTPRAEDGDTEDPAAGARRDDIAIVGMACRFPGAPDLNRYWQLLNAPRPQFSSVPEERWR
SAAFLADDPRDASSTYTDTMALLPDVGHFDAAHYGIPPRRARSMDPQHRLLIDLAREAIQ
DAGWETGGFDREETSVITSLTESGYRELSTMRIRMRQLAGGEFGARADDPRWAETVRAVD
GLHGTSVAGLLLNMGPNSISSVFDLHGESYALDSACSGGLMAVANAVFALRAGRCRIALA
GGAQLILAPDLLVGLSRIGALSRSGRCLPFGARADGFVLGEGAGLLVLRPLADARAAGDR
VYAVIRGVGTANDGTVQGGMHPEAAGQLRALRRAYRDAGLAPDSVGYLEAHGTGTRVGDP
VEVGVLRELRGDRGAPAFLGAVKAVVGHSLNAAGIAGLIKTVLAVQRGVIPPQPEFEPAD
PAGLDAARLTIPTRATPWPEPGRPRRAGVSAFGFGGTGVHLVVEEGGREPARPAPDRGPQ
LLVLSARDRPGLARYARDLAHTLTVDRLPPDRVAATLARRAPLGRRLALVVRDTADAVAQ
LTAAAQDEEAGRTAGGAPEQASGPARPAAPDTSVRTPPCTLPPSPLAPRRHWVVDDAARA
PADPPDPGRPLGPATGAARGADAAGASADSIVLEAVSRTGVFPLSDLDARMTLTTDLGFD
SLMLQELEVVLGRRVPGFSSDETYAPGLTIERLITLVAPHLTGAPAPGGPPPPQPDAADR
DTAGTCVEDFPEVLEFEERLRSITAAGTDFPYFRVHEGTVRDTTRVGGRSYLSFGSYNYL
GLSGHPAVNEAVHVAVDRYGTSVSASRMLSGERDLTVRLERVLAGFLGVEDCLALVSGHA
TNVTAIGHLVGAGDLVLHDALAHDSILQGCALSGAARRPFAHNDMGRLEHMLRVNRSRFR
RVLIAVEGAYSMDGDLVDLPAVVELKKRYGALLLVDEAHSIGTVGEHGRGVGEFYGIDRP
AVDLWMGTLSKAFASCGGYLAGSARTVRWLRHTLPGFVYSVGLTPANAAAALAAAELIAA
EPQRVRTLRRNADLFLGLAASAGLATGSSARTPIVPCLLGGSARTLRVADRLFDRGIIAD
PIFHPAVEEGLARLRFFLTSEHTERDVRRAVAVLAEEVAATEG
>B2IXI8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MTASRIEAVLAQLQEEVSNCEQALLKLIQVKKVMVENAPLTSEINRPQQKTDIAIIGMAS
IFPQSKNLQEYWEKIIHKVDCITDVPSSRWSVEDYYDPNPRTPDKTYCKRGGFIPDVNFN
PMEFGLPPNSLEVTDISQLLGLIVAKAAMEDAGYGESRQFNSDIYDRLRQRTGVILGVAL
GRQLAVPLTVRMQYPVWEKVLKGSGLSDDDTQKIIEKIKSAYVQWDENAFPGMLANVVTG
RIANRLDLGGTNCVVDAACASSLGALKMAMSELIEHRADMMITGGVDTDNSIMAYMCFSK
TPAVSQGENVKPFDAESDGMMLGEGVGMLVLKRLEDAQRDNDRIYAVIKGIGTSSDGRYK
SIYAPRPEGQMRALHRAYEDAGFSPTSVGLIEAHGTGTMAGDPAEFSSIKEVFGENNPKK
QHIALGTVKSQIGHTKAAAGAASLIKTALALHHKVLPATINVTKPHPKLDIDSSPFYLNT
ETRPWISGDDQPRRAGVSSFGFGGTNYHVVLEEYTSQHQQPYRLHKPSQSVLLFASTPEE
LLSRIQEIRQQLQSDTGEQLYTELIAASQSLEIPVTNARLGFVADSLTQACDLLQTSIDL
LTSKLQAESWEYPQGIYYRKTGIATEGKVVALFSGQGSQYLEMGRELLINFPDLGQTYAQ
IDNLLREDGLQPLSEVVFPNPVFDLDQKTAQMKVLQQTEYAQPAIGAFSAGLYKILQQAG
FKPDFVAGHSFGELTALWAAGVLNEKDYLFLVKARGQAMAAPKDPLLDAGAMLAVKGDVN
QVTELIQNFPQVTIANLNSPNQMVLAGTKAEIANVQEALKTQGFSSILLGVSAAFHTPLV
AYAQQPFARAIEKVTFNEPQIPVYTNVTGKRYPNEPQVIQKLLKEHLKNQVLFKQEIENI
YAEGGYCFIEFGPRSVLTNLVKDILSDRPHLAVALNASHLKDSDRTLRQAVLQLRVAGLP
LQNLDPYQLEYKIPEASPNQLLNVRLNSTNYVSEKTKQSFEKAMQNGHHVNGNKPNFSHS
AEKVAVNGQSPVGNGNKPHSVTANPSHSAEKVTVNGGVKSVQNGQSDQLDIKSLQPSSEL
PLSYLRAIDNLEYSLIDFSRNQHEILQVHEQSLNNQTEYTKTFFQLMEQQHAVWGNSKFS
EPHTETQQLVISSSERSIMRFHEHQTDSLRIHEQYLNYQQEYTNNFFQLLQRNYQPSPSN
TTQQNLIPPVNYQPSPVAPPAEEDNPVRETAPVALPSNGFATKSEPVLTNGNGTNGNGNG
NGAHHQATAVLDVTPLKENTAPIEIAPEPPLIIDQATLSETLINIVSDKTGYPTEMLELT
MDIEADLGIDSIKRVEILGALLELYPDLPKPDPEEVGQLRTLAQIAEYMGKIASEISGAI
PATGFVNAPNDSGSGLAVSVAEREQGAEGDGEDKGDEGNGGVTAIPSSSPPSPSSPELTN
IVFNVVSEKTGYSTTMLDLSMDIETDLGIDAVKLVEIFEALLELYPDLPKMNSEALAQLR
TLGQIVAHIEKAQESGKEFSQSPIPNPQCPTPSPQSSILRNPVRLKYLPEPDVLDFTLPD
NHIALLTDDGSLTTAKLAETLFKRGWKTVVLTFPSTVIAKQSPLPEGISRVVLADLSEEH
LREQLGAIATNYGQIATFIHLNPSTHDDISNHVRYLESEKAILRHVFLIAKYLKEPLNQA
AVQGRSSFITVARLDGEFGLGQKTNFGAIGAGLFGLTKSLNQEWESVFCRAIDLSPDLDA
ETSAQHILAELHDPNLLVVEVGYNSQERVTLVCEQEEQKNREQEIDGIPFAPNTFSSNVF
PIPNAKSQVFLVSGGAKGITAQCVIKLAQRYQCKFILVGRSTADPEPVWTEGYLSEADLK
KRIMEDFFAKGEKPTPAMVQKKFNAISSSREIATTLQAINKAGGKAEYLNVDVTDAIALQ
EQVANAVKRFGPVTGIIHGAGNLADKRIEKKSVQDFETVYTAKVKGLENLLRCVTPSQLN
YLVLFSSVVGFYGNVGQSDYAIANEILNKSAHLVKRNHPHSHVVAINWGPWDSGMVSPEL
KQAFAERNIETIPVDIGTEMLVDELASTNQETVQVVIGSPLVYIPEKLPSELRTFRIQRQ
LTLAANPFLQDHVIAGYPVLPATCGLLWIANACEQIYPGYKAFSCTNYKVLKGLIFDENL
ATEYTLELQEVAKHDINEIDFDAKIWSKTPEGKIRYHFSSQMKLKREILIPPTHEFMNLS
QDHKITATTSSLYQNGAASLFHGFTFQGVKSVLNANLDKIAIECYLPEPGERQQGQFPVQ
TFNPYIADVQIHAFWIWAQHFYQVACLPSEIKTFEQFAAVPFDETFYVSCEIKSKTESSL
VVDVIAHNQQGKIYTRMLGAKGTILPKQLDEI
>S5XLM5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Paracoccus aminophilus JCM 7686|TrEMBL
MVSEVPEDRWDRSAIFDPERQIPKSGAFLDDIKQFDGGFFGMSPREIAQMDPQQRLALTV
SWEALEDAGLSQTTLNDARVGVYFGVIWHDYELAHRTASQLHTPHSAVGQSNDVIATRIS
YAFGFQGPSLIVNTGCSSSLVALHLAQQALLAGEIDIAVVGGVNAMIAPEVMVALTRFGG
LSMDGTSKAFAASADGFGRGEGAGVIVLERLSAARAAGRRVYTLIRETAVNNDGGGNQLT
APLPQGQINLLAEIYGRGSVAPGEVDYVEAHGTGTAAGDPVEAEALGAILGAGRTVPLRI
GSVKTNIGHQEGGAGVAGVIKAALCTYHGRFVPSLHFTDPNPKIDFDGWALQVQTSDESW
TKPRAARFCGVSSFGWGGTNAHVVLQGAPEEITSPPAAAAAASQQTMAGPPLLLGLSAHT
AEALAQRRRHAADLIAQSADPRDVAFTYTQRRQRLNRRFCAIGATAAELAEMLRSADLGD
EASSEALIAAAEEEGTGEHGPGARSAGDEARSVWVFPGHGSQWLRMGKPLYDREAVFRDS
IDACAAALREFVDWDLIAFLTEETSSDWLARVDVVQPALWAMQVSLSKLWESYGVTPAVV
VGHSMGEVAAASVAGALSLRDGARIIALRSLIAKQQSGKGGMLVVDLSYEDALDLIEPYQ
DQISVGVSSSPQSTVLSGDLEALREIEALLEVEETFCKWVRVDYASHSPQMDPLKAELRA
ALREVAPQPTRFAMLSTVTLDQVAGPDLTADYWVDNLREPVRFAQAIRQLVEAGHLTFIE
MSPHPILLPALAQNFAALDVKATAIETLSRDQGTLTQFWRALCRAYCAGVPFDDGAVLFA
GARQIEVTRYPWQFEDHWFPTKGGAANIPALGRHPVIGVPVEAGRAGLSRLIWESTLGLS
RFPFLADHRVAGAIVCPGAFYIEALRAAVEQLGGEAVIALETIQFAQLLVLDEDQDYTVQ
VTFTGTAAEGGLLEFRSRPVEAEPTADWTVHCRAHFVPGQAPVAEHRAAAHRTAAVLPEN
PEAAARFYADVAATGLDYGEAFRAITAIEPVHGGVAARVEAGAALGAGLGLYGAHPVLLD
GVLQTCLAHPALLALGLRQPVPIAIERCRLAGDWAGTLSIEVEGVTPLSSQGCRIDAVRV
FGPDGSPIGEISGLELKEAFLSQDTGGSGLIDAEWGREWTELVPATGPMAPTPKSGRWLV
LAQDADLLERIKAAAPEGVALHLVTLPETAELAELLRREDWAQVIFCPDASDDRADHAQG
VSWQAITVMRAALAAPSEPRLWFLTSRSLTAPDYACANPWLAGLRGLTRTAAYEAPGLRV
SLLDLAGLDPAALRRGMALIQADQPGEEFAIGPEKDWVNALAPESLAEIDAPASYLGLQN
GGPYRLSLAQPGSTSGLHLSAAHERPLAEDKIRVRVSHAALNFIDLMKVMGIYPGLEPGA
LALGGECAGEVVAVGGALTQTGNTAGGNTAGGIAVGGIAVGQPVMVATSGAFSREVDASA
FELVALPKDLSLEAASAQPLVYMTAWYGLHHLARLRPGERVLIHSGTGGLGLAAIAVARS
LGAEVLATAGSEARRQHLREMGISCVADSRSLDFVAAVRAHTKGEGVDVVLNSLTGQALS
AGMELLRFGGRFVEVGKKDIYRDAPLNLGAFRKSLSFFAVDLASLQKEQPALFLSLLREV
AALLQDGQVPALPVTTFPVDRAAEAFDYLSKSQHIGKVVLEMTGATGLRTQALDGGQLRR
NGIYLITGGLGALGLATARLFAERGAGHLILCGRSAPGPAARDEIAALEDMGCTVSILPV
DVAQSAQLRAALLALGERVNESEILGKINGVVHAAGVLDDATLEQVSEAQLARVFRPKVM
GAWALDSVLADAPLDFFLFYSSAAALFGSPGQSAYAAANAVLDALAECRRAQGKPATSIN
WGPFADIGLAAQDARRGKRLDAQGMRELSVTQGMDALIDILHAQPVTIGIVPFEPGRWCE
AHPSVAGLQSFAALLRSETGGTARRQELLRQVVDAPVEDRARLLADGLRSLLARVLGQGE
DRISDETPFRALGLDSLMSLELRNRLEKSLGLKLAPTLLFRHSTVAALSDFLLGSLATAG
AWHEAGTAGEPPLSPVRSERRGDAQ
>K9XCC5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Gloeocapsa sp. PCC 7428|TrEMBL
MDITANPEEIAIIGISGRFPKAKNIAEFWQNLCDGVEAISQFSDEELVAAGVELSLLNNP
NYIKAGAVLEDIDLFDAGFFGFNPKEVEMTDPQHRLFLECAWEALENAGYDAQRCESRIG
VYAGASLNNYLTFNLNSDQIGSAYSFQKLIGNDKDFLSTRVSYKLNLTGPSLTIQTACST
SLVATALACQSLLNYQCDMALAGGASIRVPQKTGYLHQEGGILSPDGHCRAFDAKARGTI
IGNGVGVVLLKRLSEAIADGDYIYAVIKGSAINNDGSGKVGYTAPSVNGQAEAIAEAIAL
ADIEPETITYIETHGTGTALGDPIEISALTNVFRAETEKKGFCAIGSIKTNIGHLDAAAG
VTGLIKTTLALKHKLIPPSLNFEEPNPEIDFANSPFYVNTKLTQWNATSTPRRAGVSSLG
IGGTNAHVILEEAPSLREQESRRAGEPVRCKASLRCSNWREQERNYQLLVLSAKTDSALE
TATKNLAQHLTQHPELKLADVAYTLQVGRGVFNYRRAVICQNTQEAIKALETIDPQQVLT
HFEESTQRSITFMFPGQGAQYVNMGRELYQIPTFREQVERCCLLLEPHLGLDLHSVIYPQ
ESEKQTAAEQLKQTQFAQPALFVIEYALAQLWMSWGISPQAMIGHSIGEYVAATLAGVMS
LEDALTLVAVRGRLMQQMSTGVMLSVSASAAEVETFLNEDLALAACNAPSLCVVSGSYDA
VDKIAQKLTAKGIEYRRLHTSHAFHSHMMEPMLKPFMAELKKVQLNPPQIKFISNLTGTW
ITADEAISPDYWAQHLRQTVQFSSGLSVLLEESEQLRCAPGDRILLEVGPGRTLCTLVKQ
HAQQAAGQVVLPSLRHPQEEKSDVNFLLDILGRLWLAGVEINWSGFYTHEQRYRVPLPTY
PFERQRYWIEPEIQTQVFDKGESKQGKKPNLTDWFYIPSWKRVPLVKTKDITSHCSLIFI
DEYGVGSELVQHLQQLGQEIITVKVGEKFHQLDRNTYAINPNQADDYYKLLLQLREQGKT
LKTITHLWSLTQSQILSWEATQNLGFYSLVYLAQAIVQQQISDTIELLVIANYLYDITGN
EKLYPEKATILGACKVIPQEYPNIRCRLADILLPTSTSEDIIKQLLAELTAESEDLIIAY
RNNYRWVQTFESVALESATEDKIRLRTDGVYLITGGMGGMGLTFAEYLAKTVQAKLILLG
RSLPSDNEKIKQLEALGAEVLVVAADVTNEEQMQSAIAQSLERFGTIHGVIHAAGIAGAG
MVQLKTPEIAEKVFAPKVQGTITLNNILKNINLDFLVLCSSLSAIQGGFGQVDYCAANIF
LDAFAHWNTTRNNQFTIAINWNTWQQVGMAVNTDVPDEIKNWREESLKNAILPAEGVEVF
SRILANSLPQVIVSTQDLQVGLEQLHQLVLSLSLAQKPINSCQVSASRHSRTLQESTYVE
PRNEIEQTIANIWKELIGIEKVGVHDNFFELGGHSLLAVQTISRLREAFQVELPLRTLLF
DAPTVSELAHVIVEKQPQSEELDEIANLLAEVENLSFEELQQQLVHESPVS
>K9XMX6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Gloeocapsa sp. PCC 7428|TrEMBL
MNQTNINDNTQQRVLTALKEARAKLEAVEQAKNERIAIIGMAGRFPGARNIDEFWQNICN
GKNSIQFLPDEELQANGVDAELNHPNYVKAYASFPDFEYFAADFFGYSPREAEIIEPQHR
IFLECAYEALETAGYDPEKYQGDIGVYAGASLNSYIINLYTSALGINNVQAVISNVMGLM
PTRVSYKLNLTGPSCGVQTGCSTSLVSVHLACQSLLNRECDMALAGGVSVNASGKSGYVY
QADGVLSPDGYCRAFDAQGQGTVFGNGVGIVVLKRLSEALADGDYIYAIIKGSAINNDGA
SKVGLTAPSVAGQAKVVASAIAKAGINPETIEYIETHGTGTALGDPIEIAALTKAFRQYT
QAAQFCAIASVKTNIGHLDAAAGVAGLIKTALAINHGKIPPSLNFESPNPQIDFTDSPFY
VNTQLQDWHNTPRRAAVSSFGMGGTNAHVILEAEGRRQEVEGRRQGRNYQLLVVSAKTDA
ALEVATANLVEYLKQIPDVNLADVAYTLQVGRQHFTERRAVACQDATQVIELLSSADSRH
STQNNLVFMFAGQGSQYLDMAKELYATESLFREHVDRCCEILKPHLGLNLCDVIYSPAAV
ANINDTLYAQPALFVIEYALAQLWMSWGIQPQAMIGHSIGEYVAATLAGVFALEDALAIV
AMRGRLMQQCSPGAMLAVSLTATQVNAYLNQDLTIAAINGDKMCVVSGAIAAIEELQQRL
TAEGIGCRRLHTSHAFHSPMMQSVVEPLVAQLHQIQLSAPQIPFISNLTGTWIATSEATD
PNYWGNQLRQTVKFGAGIAEIMQLANPIFLEVAPGRTLSSLVKAQFQVDTLVSLHHPQEQ
QSDIALMLQSLGKLWQAGVEINWQGLYADEKRSRIPLPTYPFERQRYWVERDNKNTIVEH
QTDIDDWLYIPAWKRSAPVPGEETGECWLLFIDSAGLGSQLAQHLQQIGHDVVIVKAERE
FSDNEQVYAIAPDNATDYTRLLDSLQARKKTPTKIVHLWQLDQDQNDLQLGFYSLLFLVQ
ALDTPIDISVITNELHEVVGTENTEPVGTTILGLCKVIPQEFPQIRCRNIDIERDKTQIR
DLIAELTTPAFDNVAYRNHHRWLQTYEKLPKIANKPLRTGGVYLIVGDLVEGLGLVFAQY
LAEKYHARLIIVGRADLPEKHDWEKWLATHGRQDTVSDCIRKLQNIEAQSQEMLFFSADL
ASERICEIVAKADQHFGKIHGVIYAGVMGDRASHLIKSLTPTQIEEQFHSKVYGLIALEQ
ALQGRPIDFYLLQSSLSTVVGGVGFAAYAAANTFMDAFARAHNQHSTKWISVNWDAVKFD
DTDIQSNSALLNFAMTPQQVWELTERILSTTGIPQIIATPRDLQNPITEIQPTLPTIEER
PATYIPPSNEIEQKVANIMQELLGIQHISIHDNFFELGGHSLLAIQAVSRLREDFQIDLP
MREFLFESPTIAGIAKVIDDKLTQKQADMLELLQQIEQEDG
>I0K3L4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Fibrella aestuarina BUZ 2|TrEMBL
MQTNRPTDTSPFSATTRWFAEAQQVHQLVEAMASRYPEQPAVVIEGASQTYAELNEVANR
IASQLLRQAPEAPVIGIDTTRRLSLVSQLLGILKAGKAYLPLDPTYPASRLRQLIDNAHL
THCLTDGAQNLYGELGLSVVRTDEETATDAPNPLTRTPYVCVLYTSGSTGVPKGVCLGHA
GLIDLLRWEATQGPARPGSRTLQFCHLSFDASFQEIFLPLSTGGTVYLIDDSYRLDAGRL
LRFMVDNAINRVFLPYVVLQYLCEAAEAQSLFPASLEEIITGGERLRITPQIRRFFTELP
TATLMNVYGPTETSVWVTQYKLTGDAPNWPKLPPIGAPIANAEVLILSDTLTLLPDGEVG
EVCIGGPPVALGYLNQPERTAERFIQWQHPEKGTLTLYRTGDLARYVPDDKGTRLLDFQG
RADDQVKIRGNRVELGEIEVALAHLPDVQQAVAVALENEAGLKRIVAYVLMTPGQQANVA
DMRANLAATMPDFMLPAHIIELTDLPRTTSGKVDKLRLPKPESTRPALGTLFREPVSEQE
KTIAAIWAELLQISPIGLDDNFFELGGNSLLAQKTVAQLAQRGQTLPITKLYQYPTVAGL
ATYLSGQGATPQKQSRQPTAARRAESGDVAIIGMAGRFPGADSVADLWDVLAEGRETVTF
FTPEQIDSSIPVAVRTNPGYVRARGIIASADQFDPAFFGITPALAEMMDPQQRIFLEIAY
EVLEQTGYLPQVRDEIVGVYAGSGNNTYFLNNVLPNPAQMARVGAFQAMTVNEKDYIATR
TSYQLNLTGPAVSVYSACSTSLLAIAQAVESLRNGQCTVALAGGACITAPIHSGHLYEDG
AMMSRDGHCRSFDADAQGTVFSDGAGVVLLKPLADAQRDGDPILAIIKGVGVNNDGGGKG
SFTAPSAEGQAAAIRNAHLDGQIDPATISYVEAHGTGTPLGDPIEIDGLRMAFGEQPQRQ
FCAIGSLKSNMGHLSQAAGVAGVIKTVLAMQHRQLPPSLNFNVPNPAIDFGSSPFYVNDR
LTDWNVEGPLRAGVSSFGVGGTNVHVVLEEAGSTGRGATGTEVVQTQSPAFTLLTWSAKS
DASTAAYAEKLADALATADVVDVAYTMATTRPAYAHRQFAVVSSRDAIDPALLTKTPRVV
LKQQPGEVAFVFPGQGAQYLNMGRAFYEQKPVYRQAVDACAALLEPYLDVDIRTVLFSDD
EDLAAKELLKNTRYTQPALFVTNYALAQLWQSWGIEPTVFCGHSIGEFVAAHLAGVFSLA
DALQLVATRGQLVSACPRGSMLSVRLSAADVAPLLPETLSLAAINSHSLCVVAGPDEDIA
ALAQRLDKQQTPNRVLQTSHAFHSAMMDPVVDAFRAVVEKVQVQRPQKPVVSTVTGTWLT
DAQATDPVYWAKHLRETVRFADALDTLFELRQPVLLEVGPGFSSTTLARQQAGTRTVVTV
ASLHRPTPDRTEEQAILMALGTLWQQGLTPNWDAVFAGSGGKRIPLPTYPFNRKRCWIDS
PAGHMALIPTQMNVTLPTDEPIAPSSTNVPITNSDTTHTLVIPAPTDVPTPMRSEHLLDK
IKTLLEDASGIDLVDLNANDTFLELGLDSLLLTQISISLRSSFGVPISFRQLSSELDTPQ
KVADYLDTQLPAETHQPAPAPAPVPPMGNVPTNVPTYGTTSLDPMPALPGGDSALGLIAQ
QLQLLARQVALMQGGMGQGAGSMRQGAATYPTAVSPAPTTPVPPLPPTPPAPRFQPAADI
TPEEAVELKKPFGATARIERQKTDNLTPKQQQFLADLTQTYNAKTAGSKAYTQKHRAQMA
DPRVVSGFRPQTKELVYPIVIKRSKGSKLWDVDGNEYIDALNGFGATMFGHQPDFIKEAL
HAQVENGFEVGPQHELAGEVCELFCDMTNNERAALCSTGSEAVLGTMRIARTITGRSLIV
AFTGSYHGIVDEVLVRGTKKLKSFPAAAGIMPESVQNMLILDYGTDESLRIIRERAHELA
AVLVEPVQSRRAEFQPVAFLKEVRAITEASGTALIFDEVITGFRMHPGGAQALFGIQADL
ASYGKVVGGGLPIGIIAGKKSFMDALDGGFWEYGDESIPEVGVTYFAGTFVRHPLALASA
KASLLHLKEKGPALQKTLTRHAETIAESLNAAFTRLKLPLFAAQFGSLWRLKWTEDVPYG
ELLFTLMRQKGIHIWDGFPCFVTEAHTEAELAAIRDACIDSANELIRAGFFPMAVTETTS
GAWLAHQPPVPGARLGRDQQGNPAWFVPDPDQPGKYRQLEIA
>F2K069|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Marinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1)|TrEMBL
MDTKKDVAIVGIGCRFPGEANSPKEFADLIFNGVDAISEVPEDRWNKEHFYSSEHALGKA
RTKWGGFIKQPYKFDAAFFGLTPVEVSSMDPQQRLLLEVFWESLEDAGLNPYEMKGSKTG
VFIGAFTLDHLLNETSHTNWDALNSHTATGSMMTLLSNRISYLFDLVGPSITLDTACSSS
LVAVHLAAKSILNGECHQAFAGGVNLMLNPGVTVAESKANMLSPTGRSRSFDAKADGYVR
GEGAGLVLLKPLEQAITDGDRIYAVIKGSATNQDGKSSGQTVPNGQAQQTLVREACLDAK
VSPASIQYVEAHGTGTPVGDPIEANALGNVLSEGRGDGDSCLIGSVKSNFGHTEAAAGVA
GLIKTAVCMHYGELSPVVHFEKSNPKIDFASLKLTPVISRQPWPLSNMPKLAGVNSFGFG
GSNCHVVLEQAPVRKTPNSVQNGSNSQGYRLPISAKNEAALKAQCKNYIQCLQNEESDIA
IICANASLLRAHLDQRLVVSASNKQEMIEQLNLYLNSTASEHISMNKVVAKSDELITTMV
LSGMGPQWWAMGRSLLTSEPVFADMFERCDDAFSELTNDWSLKDEFTANEEKSRMAETQI
AQTSNFALQVSLAALFQSKGVVPDIIVGHSVGETAAAYISGALTLKDAAKVVFHRSRLQQ
TTKGSGGMLAVGLNHSQALDIIDSVADKVSIAAINGPTAITLAGDTDTLTGIAKQLEDQK
IFQKFLRVEVPYHSPAMEHLKEEFLAAVADIKPRETHTKLYSTVTGKLIDGRDQTPEYWW
LNLRAPVYFSDAIEKIASEEKSQLFLEVGPHPVLGGSISQQLTEKQLTGVVIPTLRRHED
EVFLVNKSVNELYVNGYPLNWKCLQPAVDKSVSLPLYPWQRNEYRSETHDSLNWLQGGNV
DSLLGRRQPTATPTWELQIRGTQLAFLFDHQVQSQSVLPAAAYAEMALQAMRQLHPNLHV
SVSALQLQKAMFISSNEPINVQLLFSQDHSSFEVYSRRNAMEDWKHNAKGQVIVSRTYRA
HERSPITVDNWQTKEQVFTKFEKMGFNYGDAFQLIDRAAFNEKGAIASITLPSQVSEFIV
HPALTDALLQLMLIAADRRQQTYLPTKIGQLTFDRHFTRGLTESLTAQCVLHSNNDNEAS
GDVHLFNNRGECLLSLTGVQLKPLTGDINEDESTWLTQIDWQRYDSPLTDLNSNKRWLVV
ADGTDLTAQVIVALEAQGQQCQPVEFNQMLDAVETNTLGSLLEQFGGYDQLVWLPSMHFD
ASSMSKRSLEKTHQFGVYAFLEVIKEVERFGRKVTIWPVSRGAHQIIPDEPMSLSAAHLI
GFSRVMAYQERPNSWQSLIDLPLQVTSDDVKAFVGTLLSSLSGKPEVGIRHGARYVAKLV
SHKQSVNPLPVRWNADESVMLTGGLGDLAILQVHQLVDAGARHFILQIRQPLPPEEEWHR
LESSSKSANQVLKLASLKRLGVSVTLTSVDITDEHALKAFIEQYQQEHPPIKHLYHCAGV
VKDKLVGELETKDFESIYQAKVYGSWALNQAFGDQLETFVFYSSYASVYGAIGQSNYASA
NSFMDGLAQWRRQCGRAALSINFGPWSGLGMAENLNLDDFFSQNGMKPITVDSGKRLAHY
LFRFDAPQVVVAPTDWSKSAVLFPNGVPALVADLVPEDKQTDDEPQFDLKEGILRAQGEE
RVKLVSQLLVEQLAQTTKLDANDLDASVGILDLGLDSLLSTSFKNRIESELPVTVSLLDL
LKGPSVNELAEKVAVTLDD
>D5P328|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium parascrofulaceum ATCC BAA-614|TrEMBL
MKNSAAETPMPDTTQHVDYLKRLTADLRRARRRVAELEGKLSEPIAVVGMACRYAGGVDS
PEALWQLVNDGRDTVSDFPADRGWDVEGLYDPDPDAAGKMYTRQGSFLRDAGDFDAGFFG
IGPSEALAMDPQQRVMLEISWEALERAGIDPLGLRGSATGVFAGVIHAGYGGEVKGELEG
YGLTGSTLSVASGRVSYVLGLEGPAVSVDTACSSSLVAMHLAAQSLRSGECDLALAGGVT
VMATPAAFVEFSRQRALAPDGRCKVYAGAADGTSWSEGAGVLVLERLADARRLGHPVLAV
LRGSAVNQDGASNGLTAPNGPSQQRVIRAALADAGLTAADVDVVEGHGTGTVLGDPIEAQ
ALLATYGQDRPPGRPLWLGSIKSNIGHTSAAAGVAGVIKMVQAMRHGVIPRTLHVDVPSP
HVDWSVGAVSLLTEPQPWPARDGGRRAGVSSFGISGTNAHVIVEEPPAEPETPEAVAAQT
DDSRPVVPWVVSARSADALAAQAARLSAYLDAEPGLRPRDVGWSLATTRAALEHRAVLVG
SDRDTLRAGLAGVASGEPGPGAVVGRSRSTGKRAFVFPGQGAQRLGMGRELHQRFPAFAE
AFDEAVAAVDAHARRPLREVMWGTDPELLQSTEFAQPALFVLEVALAALWRSWGVTPDVV
IGHSVGEIAAAHVAGVLSLRDAARLVAARGRLMAALPPGGVMVAVTATEAEVAPLLDGGV
SLAAVNGPAAVVLSGERDAVTAAADRLADCGRRVRQLAVSHAFHSPLMEPMIEEFSAVAA
GVSPGSPRIDLVSNVTGRPAGPGYGSADYWVEHVRRPVRFADGARCAAALGAGAFVEVGP
GAALTAAVEQSLGAEPAVAAVSMAKDHPEVDSLLLAAGQLFASGADLDWAAAFAGLAAHR
VDLPTYAFARRRFWLLSESVGGRDTAGLGLAAAGHALLGAVVERPDSGGVVLTGRLSTVA
QPWLADHAVAGTVLFPGAGFVELMLRAGDEVGCPVIEELMLSAPLPLPAAGAVCVQVVVD
GAGEGGSRAAAVYSQAGSQWTLHAQGVLGEGSPAPDADLSVWPPVGATAVDVAGAYDDLA
GRGYGYGPAFRGLRAVWRRGAEVFAEVEAPQDAGVAVGGFGIHPVVLDAALHALGVADEG
AETVLPFSWQGVCLHAAGASRVRVRLAPAGKDAVSVELADSSGLPVLSVRELVTRPVSAA
QLSAAAAARTGGGELLEAVWSPVALPDNPDGPAPEVWRPPANGDGVVASVHAATHAALGL
LQSRDEGSAPLVVLTRGAVALPGEDVTDLAGAAVWGLVRSAQAENPGRVVLVDSDGSLDP
RAVVGCGEPQLVVRGGVAHRARLAPVKVHPVLRLPEPPSVWRLAAGDAGTLEDLAVQSGP
PAELLAGQVRVAVAAAGVNFRDVLVALGMYPGAAQLGAEGAGLVAEVGPGVTDLAVGDAV
LGILGLTGSEAVVDRRLVTRVPPDWSLAEAAGVPVVFLTALYGLSVLAGLRAGERVLVHA
AAGGVGMAAVQLARHWGAEVFATASRGKWETLRAMGFDDAHIADSRTLEFEEKFSAATGG
AGVDVVLNSLAGEFTDASLRLLAPGGRFIEMGKTDLRDPDTLTGVGYRAFDLMEAGPDRI
AEMLAELMRLFAAGVLKPLPVRAFDIRCAADAYRFVSQARHIGKVVLTMPGGPAGLAGGT
ALVTGGTGMAGSAVARHLVERYRVPHVMLVSRGGERAAGVPGLVDGLRATGAEVTVVACD
VGDPEAVAGLLARVPARFPLRGVFHAAGVLDDAVIASLTPQRVDTVLRSKADGAWHLHEL
TRGLDLSAFVMFSSMAGIVGAPGQGNYAAANSFLDGLAAHRRAHGLPGLSVAWGMWAEES
AMTGHLGERDKARMSRAGLAALSTGQALDLLDAALLAEPPVVVATRLDATALAHAGAALP
PLLSQLAARPARRVLDPTDMVSLTGLRARLDGLAPEQRRRELVELVCGNAATVLGHSTAD
VDAEQAFADLGFDSLTAVELRNRLKIATGLTLSPTLIFDHPTPAALAEHLDGQLAAGTSA
QPPDRMARFNDVARELQALLGRPDWSPGDKAQLVARLEGLLSTLAGPAQPPHPEDPDDPF
DDDIATATESQLFAILDEEIGP
>A0A3N6FHE1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-17|TrEMBL
MGTVLMPGTAFVELAVKAGDDVGCDHLEELTIEAPLVLSPERAVGLQLWVGPADEAGRRA
VEIHSRDLGRAEAAWTRHASGALTSGGDRPDAGDLTVWPPEGATEVPVDGLYDYLTAIGY
GYGPVFQGLRAAWRLGEEVFVEVALPDRTETEAARFGLHPALLDSALHAMGLSTSHDADG
DGGGRNRLPFAWNGVTLYAAGADALRVRITPKDSQDSTGAKGPEGVSLTLADPKGALVAV
IESLVLRTVTSAQLDGARQSTHHDSLFRLGWSPAAVDRTFPDARWAVLGADHLGLVASGV
GVDAFAALDDLAAAPTPPPAVLLAFAPSATDAAASEAAHERTAEALETVQAWLADERFTD
VLMVVATRGAVAVDGEDVTDLAQAAVWGLLRSAQSEAPGRFVLVDIDDADVSAQSLVTAV
ACGEQQLAVRAGEILVPRLDRVAVAALDAEPVADPDAANREDADAADREDADQGDTAGQP
GTALITGASGFLGGLVARRLAERGTRHLLLVSRRGADAPNAAQLAEELAESGVEVTFAAC
DTSDRSALAAVLAEIPAAHPLTTVVHAAGIVDDGVLASLTPQRLADVLRPKVDAAWHLHE
LTKELAVREFVLFSSAAGTFGGPGQANYAAANAFLDGLAQHRSAQGLPAVSLAWGPWAES
GMAGRMDEADIARMARSGLAPLTQEQGIELFDTGRAAGHAVLMPTRLTAGSPQVRPDAIP
PLLRGLIRGPVRPAAAGKSGPTGASAADLKQRLAAADTAERDRILLDILRTAIADVLGHG
SPAAVEVTRGFLEIGFDSLTAVELRNRLNAETGLRLPSTLVFDHPSPEALATHLRDQLVE
DGATSALALLAELDRLERVLAAVASDDADRAAVTDRLRGLMSTWNGGGTEADASGGQDLE
SATADEIFDLLDEELETS
>A0A3N6E8M2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-17|TrEMBL
MAPESAVGALHQALADDATLLTVADVDWQRFAPAFTARRPSPLLGELADVQRVLEQDHGG
ADADGRGGDAAAQLRARLAQANESQQNRILLELVRTEAADVLGHATADVVRPRRGFVELG
FDSLMAVEVRNRLARHTGLRLSTTLLFDFPSPAALAQHLRAELAQELSAEASTSVAAVLN
ELERMLSGLSTDDVDGVDITERLQGLLTTWSGAQVRMASAPPEAGESAAAAMDSDLESAT
SDEMFDLIQREFGKF
>F1T733|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
MDSLYEKLRSGDLCPEEVLAIIKGTEAGPEEALCYYEECLSIQPRDGTLPTKEDRTLLFI
AEDMESINKFCNNYGYFSENTISVYIGNEASSNMKYNYQINKTDSASYINLYEQLNKKKC
SEWDIIYFSQSRNTGADTSAKEIDNSIQTAYSITQLIRAFSKDYSTIRFIHGFTKDNHTN
YVNIALSGMLKTISVECSNLMHKNIQFENMNEREICSRLIEEVNFDISDGTDISYISNKR
YISEFKPIQKSSETENKQLDIFNQGVFIVTGGMGALGQILAEQILVYRPQRVYLLGRKYP
DKAILDSVSRIDPSSTVIKYLQCDIEDSIACQQVIENILEKDGHVTGLFHCAGVIRDAII
VNLKLEDFYQSVNPKIKGLINILDSFIKYGLDMKFVKLYSSITSVMGNMGQTAYSYANGY
LNAFAYDIQSKYHMFNIQAICWPYWEQGGLTVDGEKLNRLYEQTGQKPLSTANGKIVLEN
LMSLDSKCPIAMYGDKAKISRYMKEVRRQKVYTMEENEIQGDEIVSASKLTKEDVTDYVQ
GIISDIIKLPKSKLNITTTWENYGIDSLAIMRFNEIIEDVIPNCPKTLMYEYRNIEALSE
CFFEKYAGRLEKLLKKEIAPTPQKVKSSVPDKGFGAIQNNRFKKVTQEKATPSETKSDVA
IIGIAGRYPKADTLDEFWNNLLEGRDCVVEIPSDRWDYSEDYNTDKSKHGYTNSKWGGFI
NDFDCFDAAFFKITPREARYMDPQERIFLECAWHGLEDAGYTAKMLKNHQVGVFAGIMYS
HYQLYGIDYDKPGHKMAFNSSYASVSNRVSYHMDFHGPSIAIDTMCSSSLTAIHLACESI
YNGSSSIAVAGGVNLSLHPNKYINLSQNNFLSSEGKCRSFGEGGDGYVPSEGVGVVILKK
LEDAQRDKDIIYGVIKAAAINHGGSSNGFTVPNPAAQTEVIQKALKEAKTDAANITYVET
HGTGTPLGDPIELSALTKAYGITEKCAVGSIKSNMGHAESAAGMAGLTKVILQMKYKKLV
PSIHCDQLNKNINFNELPFVVQKKTETWEHKKSNGKDIPYLAGLSAFGAGGSNAHLLIEE
YADKQDIKQKLGNFDYNILVISAKNKKDLVNYCHTYIKYLRESRDNNVALEQICYATQFY
RNLLNEKLAVIGLDYEDMINKLVAFINSAQEQEDIIYVSEEDENDDINKFEYDFNRNPKR
QDFINLAREAFYSSNDDWSIMWRDIKYPKINLPLYPFEKKRYWLSDDWKKPEVKAESLTN
VSAMNRLHNLSTLKEIKFKTLFNVSDFFVKDHKVKGKLILPGAAIAINAKAIGNILAEGK
LKSIDDLTFVSPVSFENEEVELMSYVDNKTLDIKTKMVSGTREIAIGIGTLNLTKELELN
YVTDIEAINRRCNQKIFSEQLYKSIKQHGLEYGGSLGIIEKISYSEEEALVELKSFKQNY
SNYFEAEFDSTVIPCIDAAFQSVFVFGSKFDLGDNKVILPYKIGSISCNKSSFTPEYIHV
ICNNTKDINFDIQIIDDKGRAQIKIEKLSMMEIKEKKYDIPDILRLLKGNEITLEKAAAI
LEEEFNDK
>A0A5P9INU7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Halomonas sp. THAF5a|TrEMBL
MTRRVALIGVAHRMPGTTPETFWDDLQAEKDLVTQVASDRWSHEAFQHPDRRHPGTSVTF
AAGSLGDISGFDAEFFGISPREAAHMDPQQRMLLELTWEAMENAGIAPSRLRGSRCGVYL
GIASMDYAYRIADDMAVIDAPTATGNTSSIASNRLSYLFDLQGPSMSVDTACSSALVAFH
QACQAIRSGETPMALAGGISLHLHPYGFIIFSKASMLSSSGRCRAFDADGDGYVRSEGAG
MFLLKDYDQAVADGDPILAVVAGSAVNTDGHKQGLTVPNADAQVALMRQAYAQAGITPDE
IDYLETHGTGTAVGDPIETRAIGEALAQGRQQPLPIGSVKSNLGHLETASGVAGLAKALY
SLRHREVPATIGIRRLNPKIRTDEWNLEVVRRPLPLKAEGRLVIGVNSFGFGGANAHVIL
ESPPTPQTPVQTVSDADRPLPLRVTARGSEALAASASALAEHLENAEDSLYGIAHTLYRH
REHHRDGLLLFATRREEAARRLAAWSAQDEQNDAGLGIVRGTRLEQAQGPAFVYDGNGCQ
WETMGRDLLASSQVFASAVDEVDALFEPRAGFSLRAELEGRHREDHDSEDRFARTEIAQP
ALFAVQVGITRLLAAYGIHPTVVTGHSVGEVAAAWASGALSLADAVRVIHLRSHYQGLTR
GQGEMSAVGLGEDDVLALLEGPEYAELSLAGTNSAKGTTVAGPAEALTRLEQALDAQRIF
AKRLPLDYAFHSPAMNPIEKDLVAELAGLSPKPSRVPYVSTVTGARLEGEALGPNYWWDN
IRQPVRFEAAMASVVEAGTNVLIEIGSHPILRRYLTEALTQADQPGLVIGTLERSRNGAA
CLERTVGEALLSGIAHDDTPWFPVDSPRVELPRYPWQHRRHWIPGTASAGGLLARHYEHP
LLGYRLAQQTLTWESELDTGRHPWLGDHVVGDAAIFPGAGFVELALAVATQWRAPALLDI
EELEIQAPLMLDGPHGRTLRLAVEPTDGRLAVRSRETGSDGDWQLHATARIMEQSRGLML
TRRAPTCPRRAPDVTLPDHLTAAARLGLAYGPAFQAIDRAWVEGDEVIGTVYPTEAIEAQ
RDTLWLHPGILDSAFQLFLPLLDHLEAAQDGLAFVPVRVGRVQFDPAAGAPTLARAKLIK
RAPYSFTADFELFDAEGRAVAVLTETRFKALRLTKGDENALSYLDVALTPAPRREGRLPA
SLAALQAALPKLIDGYADATQRRYAQEVAPLLDRLVEAFAEQALAPELDEGWLSQARYQA
LAGRHLQARPLLDQLLRLLEDAGRLEADDGGWRLADTDTVAPEAIWQLLIQDYPGQGAAI
ARVGRFGLHLHELLAGDADAETINLSREGLARFNRDLIGHDGWQAIAAPLAAALMETRAA
LPTGQRLGLLEAGVGAPILGERLAETLDPDRCDYRILAVGDQAWQQAAALRDRQPRIELE
TLEAPSTAGAPAELALVSLDITDREGSRRLLEALPERLAPDASLLLVGLTPSAWLDALLA
TPGLGDEGEPAAGACEREDVIAWLERLGAEEVYPLPLEGETGAYLVHARLPGEPRVEPYA
LRHRLLVADETQRSLALSLQEALIAQGDNVTLLDAPPMAEHWQALQHAASQEGAALDILD
LAAPDTARCRRAAHWARRLETPATETTLWLVTRGVAAMWTATDAVASDDAALWGFGRSLA
NEADAFEIKLVDLPDDADLPEAADEAIRQALLLELGAPDAENEMVIDAEGRRFATRLREL
PAPEQRLAEEDGNGPGAMTLGFPLPGQLRHLSWMPRPLPSPAAGELEVRVEATGLNFRDV
MYTLGLLSDEAIENGFAGPTLGLEFAGVVERVGSGVDDLSPGDAVVGFGPASFSDRLIAD
RQAIAPLPTGLDFAAAATIPTTFFTVYYALKHLARLAPGEHVLIHGAAGGVGLAAIQVAR
WLGAEIHATVGSDEKRDFLRLLGVERLHDSRALTFAEEILAETDGRGVDVVLNSLAGEAI
NQNLRVLRPFGRFLELGKRDFYENTHIGLRPFRNNLSYFGIDSDQLMKACPELTRTLFTE
MMALFEDGTFTPLPYTAFGHHQVVEAFRYMQQARQIGKVVVTQEHALAGSAQPAATTTPS
LSLRDDASYLVTGGLGGFGLRTAEWLADRGARHLILIGRRGLDGPEAREGVARLQAQGVT
VTAAACDVNDREALAALLARCRDELPPLRGVVHAAAVIEDALIRNLEDERLERVLAPKVA
GARHLDELTRDDPLELFVLYSSATTLFGNPGQAAYVAANHWLEALAAERRARGRPVTCVR
WGAIEDAGFLARHTRTREALQERLGGSALRAEAALDVLEAMLEASREGQTPSLGVLELEW
SALARFLPTAAAPRFSEIAGAASGDDHQDEAGQDIARLIAELTPEELHATVTELLKAELA
SILMIEEEKIDVHRSVYDMGFDSLMGVELMTAIEARLGVRVPVMVLSEASTLDRLAAVLI
ERLSRDDAPDDDDELAALAARHGAETPSDHDTPTSQEAIS
>A0A1U0V3T6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus subsp. massiliense|TrEMBL
MLRREASALLAYVAEHPRIAPNRIAGMIFRTRVARRYRALVTVENHDQLVAALRTVVAGT
EHPLVVRNSEPATARRHGFVFPGQGGQRPGMGRLFYDAFPSFRAEVVRCADLFAKQFGRS
PLSYLLDHQLPPNDSATVVQPALFTQMAGLAALWRTVGVIPRAVVGHSQGEIAGAYVSGV
MSLDDAVTVVGTRAGIADEFPADDYAMAVIATDRDTCEELLARNSGWAELSVVNSPSMVG
ISGQRETVHQIVEHLTEDGVFARVIPVRYPAHTSMIASIGAQIRRALTENLHAGEFTVSE
IDCIGATLGTAISPEMPVDQYWFWNLRNAVRFDRAVATAAAAHVDTFVELAEHPTLQLAL
RENLAALGSERTACVVSTSRRNATDLAEFTANLAKIAVHDLDYNWDALRAEAPDRVSLPL
RDFPNVQNNDIPLWLSYRTDTSGVAVPKQPAVTPEAERRVDTGNDSRAYPRLLREAWTKM
TRRSMMPPRSYAFIDGTGDAGALVEALRDNAPNFGSSARIVTGTNESGTGDADTVVIVLP
SPALLDDREAAEAVARFFGNRTWWPGLSSTVTGCWLVTVGGEQAVADDRPAHPVHAAIAA
GFRCMGTEHPGIAFRHLDLTPDIAGPDKADNILAALQSAGESELALRADGMYAKRVLDID
QDGDESSRAVAPDHVVITGGTGKLGQEFCEHYARMGTRQITLISRSGETDAVTGRLDAIR
RSTGAKVRALPCDVTDTAAVTALADQLRDTPADLIIHAAVDYSDTLLAEVTVDKFQDALR
AKVIGISNVLDTVPRTDSCRVMLCSSLAATIGGKGQLMYAAGNRMLDVLASTRRASGLDC
TSIQWGQWTVHLDLGDTGIAKLAAAGVHPMRPADALAVGMGRHHGNTLVGAFDLTRARAM
LGVFGYGPLLSELEDNSGPVAPAETIRPAPVVPENRSGHLVQLLAEVIGADHADSIDTAM
PMVAMGLDSLQALEFRRRVQAELDFELPVQDLLGGASVDHVIDALTAQSR
>A0A2S9YGC8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Enhygromyxa salina|TrEMBL
MTTTLEDYRTRLQLALGRLAELRSELERQRRATREPIAIVGMGCRLPPAIRSPEQLFEAL
LAGHDAVREAPPARFGELAGLPRAGYLDEVAEFDAEFFAIAPREAAAIDPQQRLLLEVVW
EALERGGLVPAALPADRVGMFVGLGASDYAELSLTGPAERSDIYTLTGVGASFASGRLAY
HLGFRGPCLTLDTACSSSLVALHLAVQSLRRRETEVAIAAGVQLLLTPTSSGLLGRSGAL
AADGYCKAFDAGADGFVRGEGCAAVVLKRLSDALRDRDPIAAVVRGTASNQDGRSTGLTA
PNVLAQRQLLRRALSDAGLPAASLGLIETHGTGTALGDPIELEALADVFASSDDDAPIVL
GALKSNLGHLEAAAGLAGVIKAAVCLERGLIPPNLHFHALNPHAPASALTRFELPTAPRP
WPAASDGGPRRAGVSAFGMSGTNAHVIVEQAPACEPRSPSSAGRVYLLPLSARSPGALTE
LARRCAAVLEAERDPGDVCTSAATRRTHFVEHRLVVRGRSGAELAAGLRAVSEGRASAAV
SLGRGQARRPVLVCAGQGSVWPGMGRALVDDPLAGQVLRACDALAREHGDLALIDELIAE
PERCRLNHTRVAQPALLAMSLAIAARLAGWGVEAAAVIGHSVGELAAAQLAGVLDLDQAM
RLACARGRVMEANHGRGAMAAVALGVDRARALVDRSAGRLAIAAVNGPSSTVVAGDAEAL
AQALRALAEDGVRHRRLALDYAFHSPQMEALAGPLRAGLGRVEPRAASLPLYSTVTGARV
RGPELDAAYWTRGVGSAVKFADAVAAALADGHRLFVEIGPHPSLSAHLDAIAEAAEEQVD
VVATLREDGAADALHRCLAELHVHGCALDFESLAEDRDRFVGLPSYPWQGRRCWLDDGFA
RPSSAPPAGELSAPPVPESRPRRPESRAALVDALHQEVAAVLGLSPDQALSPRVGLFELG
LDSIMAVELRARLQARFDLRLAATLVFDHPTLEAIADHLEAVAAAAERPAGGPAIIRRAG
DDEAIAIVGMACRFPGGANDLDSFWQGLRTGADATSEPPAERWDHDRFYDADPAAPGKTY
GRRSGFLRGLDVADFDAAFFKISPAEAAALDPQHRLVLELGWEALEHGGQAPDRLLGSAT
GVFLGIATADYAQLATQGSLAELDTYVSTGNAANTAAGRLAYFLGLEGPVIALDTACSSS
LVATHLAVQSLRRGESDLALAGGVNLILTPTIDVMYARLGALALDSRCKAFDAAADGMVR
GEGGAMVVLKRLSDAEREDDRILALIRGSAINHDGRAAGLTVPNGAAQRGVIRAALADAR
VEPAAIHYVETHGTGTRLGDPIEANALVAELGRGRRADQPLWLGAAKASFGHLEAAAGVV
ALVKAALVLGRRELPPQRNFETLNPAIDPGAVALRLPTTVEALPAGPIFAGVSAFGMSGT
NAHLILESARGPSQREPEAAAEAEADADAEHGGDALLLPISARSEAALRELARAYRARLQ
ACESLAELAQLCRAAALRRAHLEHRLAITGATSSQLLEALDAYLEGRAHGGWFTGANARA
RVAFVFSGHSSHWLGMGRELLAREPEFRASLEASAAAAERVGMPGLLELLTTDDEERWAS
VSVVQPLVLAVQIAVAERWRRWGVDPEAVVGHSMGEIAAAHVAGMLELDDAMRIVVARSR
LIARVEGEGKMAVVGLDLDQTRARIEGRALSVAASNSPRLTVVSGANAAVEALVADLRGA
NVFARVMAGTRGAGHSPQLDPLLPELAEALSSLEPRAPTIAFYSTVLAERVDAELLDGDY
WVRNLREPVYFAATIERMGAAGFDSFVEVSPDPMMLGAIEQILRPRGGAMTRVASLERGG
GERATLLAGLAQLYVAGVEVDWTGLHPHGSRAVALPGQAWQRRRHWLAAGRYVEPGRPHR
DARLDPLLGRRLDSAADPGRTIWQLDCGPGPSPSPVPVIELQGTQVLAAAYLLELVEAAA
RATWPAEALELGALEFEGAVIAEADASVELQLVLDAPEAGARGAAVQLFARRGSDEFRRR
GRARLMPRAEREVPELEDFDQLLARCHRRDDQLWSRLAARGVELPRAVAAGGELRAGPEL
EGLERLVRVELDPPRGPRRRSAAVEAGLWVLAELSQDRGAPPVPGQLPSLAAITRVVELG
GEDHEPPAWIHARLAPAEPGESRARPRPAALTVYDAGGVPLTHAELELSGRGDLELARAA
VDRLLPDWLYTLDWTPCAAADPRALTGVTLVIADELALAGACVDQLAAAGSDALGIDAAT
LVDLDACHHALRRARERGPLRAVVLLQLDDVDAAELPARVDARARLLLDLAHALINEGGK
LRLQLVTRASQPVRPAASLTPSGLAAAPLWGLARSIGLEHPGVDVRGLDLAAEPHRDDPR
RILAELGADDREEAVAYRDEQRFVQRLCRAAPPPDPGPLRLRGDGTYLVTGGLGGVGLQL
AERLFEAGAGRLVLLGRRGLPVERPAPDDPMLARWLAVEQLRARGAVVEIAVADVGDPKA
LASVLARGPGLASLRGVFHCAGVSEPRPLADTRSAQVEAGYRAKVAGSWALHQLTAELEL
DHFVGFSSMASVWGAAQLGPYDGANHFIDVLMHHRRGLGLPGLALNWGGWAGAGMTTAEV
QRYAARMGLGVAPAAQFLAALERLLGADRPQLALGPVDWRMFKPVLESYGARPLLDGLAL
EEPEPHGRGPLHARLVETELRDRWALLVTELCGAVAAQLGHASGEAIDEAAGLFELGMDS
VSSVALRNELERSLGLSLAPTVAFEHPSVLALASFLIATLELDAPRPDARVAAEPADPEL
AGLSEAELEALLAAELDQGPS
>G6FSF1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Fischerella thermalis JSC-11|TrEMBL
MSHTVEFSRNGLEIAIIGMAGRFPGAKNIEEFWQNLRNGVESITTFTNEELLAGGIDPDL
LNDPNYVKAGAVLEDIELFDAEFFGFNPREAEIIDPQHRLFLECAWEAMENAGYNSKMYS
GLIGVYAGAGSNNYVLNIYSNQNIRSSIDRNQLFFGNDKDFLATRVSYKLDLEGPAVGIQ
TACSTSLVAVHLACRGLLSGECDIALAGGVAIDVPQKEGYLYQEGGIVSPDGRCRAFDAK
AQGTIFSNGVGIVVLKRLEDAIADGDCIHAVIKGSAINNDGAFKVSYTAPRIDGQAKVIR
AAQVMAEVDPETITYIEAHGTGTSLGDPIEISALTQVFRASTDKKGFCAVGSVKTNIGHS
DITAGVAGLIKTVLALKHKQIPPSLHFQQPNPEIDFDNSPFYVNTTLSEWQTNGIPRRAG
VSSFGIGGTNAHVILEEAPVVETRGGASLQSRPWHLLLLSAKTRTALETATVNLAAYLQQ
HRDLNLADVAYTLQVGRQAFEHRFMVVCQNLEDAVQKLEFANQEQVSTYLKELHNRPVVF
MFPGQGAQYVNMGRELYQTEPIFREEVNRCCELLKPHLGIDLRHVLYPSEEQIEAATHQL
QQTYITQPALFVIEYALSQLWMAWGIQPEAMIGHSIGEYVAACLAGVLSLEDALILVAVR
GRLMQELPTGAMLSVHLAEDDLQPWLGKEVSLAASNAPNLCVVSGSEEAIAHLQSRLNDK
GVECRRLHTSHAFHSPMIDSILESFTNQVEKIKLNPPQISFISNLTGTWITAKEATDPTY
WAKHLRQTVRFAQGMAELMTQPERILLEVGPGMTLSTFARQSRTDEPTVLATLRHPKYQK
SDSAFLLTTVGQLWLAGVQVDWYKFHAQQSRQRIPLPTYPFERQRYWIEAQKVDNSHPQI
KLTRKPNMADWFYVPAWKRVMLLEPWKTEGLNPHKSCWLIFVDPCGVGSQIAKRLEQAGQ
DVIIVTIGEEFTKLSDCIYTINPQQQDDYTTLMQTLRELGKTPQNIAHFWGVTANTTSLG
KTLHPKTQLGVEDFCKSQDLVFYSLLFLAQQLTKHHLTTPVQIIAITNNMHEVVGQEQLQ
PEKATVLGPCKAIAQEYPHMSCRSVDIVIPESETFLEKQLIDQLMAELTQQPSDLVVAYR
NGHRWVQTFEPIQLNEVVPEKTRLREGGIYLIVGDPVKGLGLVFAEYLAQTVHAKLILIE
NSELPARNEWEQWLATHDQHNNISDQIRRIQALEELSGDVLIIKADVVNEEQMQQAMTIA
YERFGQIHGVFYVPEISGNEKSTLSIHEIGKTECEQEFKSKVHGIFVLEKVLQDKKLDFY
LLQSSLSSILGGLGLVAYSAAYLFMDAFVHQKKQQNSVPWFSVNRQAFISDLEKEKYVSL
GSTATELFMTPKEVWEAFQRILSMGSANQIVVSTGDLQARINQSLKLKPLETVSNSKNSQ
QADSFSQHSRPNLQTVYVAPRNEIEQTIANIWQEILGVSLVGVNDDFFELGGHSLLAVQV
TSRLRETFQVDLPLNSILFEASTVAGLAAVIAQQQPQQEELEEMVALLQEVKSLSAEEVQ
AEMAKDFWSS
>A0A3G4VMA5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-16|TrEMBL
MNEEKLRYFLKRVTADLHETRRRLQEVESEEQEPIAIIGMSCRYPGDVESPEDLWRLVSD
ETDAISAFPTDRGWDTGQLFDADPDGRGTSYVQEGGFLHSANRFEPEFFGISPREAVAMD
PQQRLLLETSWEAFERAGIDPTSMRGSRTGVFTGVMYHDYASRLRAVPPEVEGYLGTGGS
SSIASGRVSYTFGLEGPALTVDTACSSSLVTLHLAMQALRKGECSLALAGGVTVMPTPGT
FTEFSKQRGLSFDGRCKSFADAADGTGWGEGAGMLLVERLSDARRNGHRVLAVVRGSAVN
QDGASNGLTAPNGPSQQRVIRQALADARLTAADVDVVEAHGTGTTLGDPIEAQALLATYG
REHTEDRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAIRHGRIPRTLHVDEPSTKVDWSAG
AVSLLRDTVEWPETGRPRRAAVSSFGISGTNAHTIIEQAPVAVPAEPAESADTDTDADAD
AVDAAANADEPRPQARRRTVVPPVLPWLVSARTEEALRAQAERLLTHLRAHPDQRPEDVS
HTLATGRAALEHRAVVVAGDREKALANLAALASGDTTTAQVVRGVAGARGKVAFLFTGQG
SQRLGMGRELYDAYPVFAEALDAVCAELDPRLEIPLKDVLFGADAALLDETRFTQPALFA
VEVALFRLVESWGVKPDFLSGHSIGEIAAAHVAGVFSLEDACTLVAARGRLMQALPSGGV
MIAVQASEEEVLPLLTDRVSIAAVNGPRSVVVAGDEDAALAIAGALPDRKSKRLTVSHAF
HSPHMDGMLDAFRQEIEGLTFAAPRIPVVSNLTGAPVTDEMGSADFWVRHVRDAVRFLDG
VRALESAGVTTYVELGPAGVLSAMAQSCLTESTGPVAFVPALRKGRSEAATLTTALAEVH
ARGIAVDWHAFHRDTGAEHVDLPTYAFQREHYWLDAGSLGGDVTTVGLRSADHPLLGASV
SLADADALLLTGLLSLTTHPWLGDHRVMGSVLLPGTAFVELALRAGEQVGCDLVDDLTLA
APLVLPEEGGVELQISVAAPDASGRRSVVFHSRADRAGDDEPWVRNATAILTEGAGDSPG
FDLVEWPPAGADTVPVEGLYEGLSDSGFGYGPAFQGLRAAWRRGEDVFAEVSLDSETEPG
AEQFTIHPALLDAVLHGIGLGSLVEDTGQGRLPFSWSGVAVHSVGADSVRVRLSRAGRDA
VRLEIADVEGAPVASVDSLALRAFSPEQLGRQAGGHGDSLFRVAWSQVASGESFGDWLML
GEGSQVFADLAGLAVAVAEGGEIPAALVVPCVEPAAEDVAGAVHAQTGRVLALLKDWLSD
RRFADARMVFLTRGAVEAVPGEGVADLVHAGVWGLVRSAQSENPGRFVLVDVDAEGDVEA
GLSAALASGESELAVRGGSLLVPKLARAAVAADTAKGWATEGTVLVTGASGSLGGLFARH
LVTEHGVRRLLLVSRRGEAAELSAELVGLGAEVSWAACDVADRDALAAVLAAVPAEHPLT
AVVHTAGVLDDGVVGSLTAERLSAVLRPKVDAAWNLHELTRDLDLSAFVLFSSAAGVFGG
AGQANYAAGNTFLDALAAHRRAQGLAGVSLAWGLWAEVGGMGGDLADGDRDRMNRGGVDA
LSPQTGLALFDAAHAADDPLLVPVKLDLAALRAQAGSGLLPPLLSGLVRMPTRRAAKGGT
FARQLSALAKERQPGAVADLVRGQVAAVLGFVGPEVVDPARSFNEVGFDSLTAVELRNRL
GAATGVRLPATLVFDYPTPAVLAEYLYAELLGVQEADVAVVAAPVHDDEPIAIVAMACRF
PGDVRSPEDLWRLVRDGRDAISDMPADRGWDLEGLFDADPDRQGTSYSTAGGFLHDAHHF
DPSFFGISPREALATDPQQRLLLETSWEAFERARIDPASMRGSRTGVFAGVMYNDYGTLL
HRAPEGLEGYMGTSSSGSVASGRVSYTFGLEGPAVTVDTACSSSLVTLHLAVQALRNGEC
DLALAGGVTVMATPGTFIAFSRQRGLATDGRCKPFAAAADGTAWGEGVGMLLVERLSDAR
RNGHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRQALTNAGLTSADVDVVEAHGTGT
TLGDPIEAQALLATYGQDRPGDRPLLLGSIKSNMGHTQAAAGVAGIIKMVQAMRHGTVPK
TLHVDEPSPHVDWSEGAVELLTESVAWPETGRPRRAAVSSFGISGTNAHTIIEQAPDEAA
VTVAETGTEPVLPYVLSAKSADALSAQAARLRTHLQDTPEAGAADMAYSLATRRAAFAHR
AVVVAGTREELLGALAALADGDVSAAGITSGTVGAAGAGKLAFLFTGQGSQRLGMGRELY
EAHPVFAAALDAVCERVRLPLGKVLFGTDAELLDRTEFTQPALFALEVALFRLLESWGVK
PDFLSGHSIGEIAAAHVAGVLSLDDACTLVAARGRLMQALPGGGVMIALEASEGEVLPLL
TDRVSIAAINGPRSVVVAGDEDAAVAVANAFPDRKSKRLTVSHAFHSPHMDGMLDAFHEV
VRGLTYSAPRIPVVSNLTGALVSDEMGSADFWVRHAREAVRFLDGVRALEAAGVTTYLEL
GPDGVLCAMAQACLTDDTRGAAFAPALRKERPETVALTAAVAEAHAHGAPVDWESYFAGT
GARSIDLPTYAFQHERYWIDLPVGSFADAAAAGLRPADHPLLGASVMLADADGLLLTGRL
SVATHPWLADHVVMGAVTLPGTAFVELALRAGEQVGCDLVEELTLAAPLVLPEDGGVELQ
IAVGAPDESGRRPLAFHSREGLAADDALWLRNATATLAVGAQEPPVFDLAAWPPAGSEPV
DVEELYEGFAESGFGYGPVFQGLRAAWRKGDEVFAEVGLGDEQGPDAEQFTIHPALLDSV
LHAIGLGSLVEDTGQPRLPFSWSGVAVHSTGADTLRVRLSRAGREAVRLEIADAEGVPVA
SVDSLALRAFSPEQLGRQVGGHGDALFRVEWRELMPSDALFADWVMRDGVDAQVLDDLDT
VPGALVLSCREPAGTDVADAVHAEAGRVLTLLQRWLSDDRFADARLAFLTRGAVTVAPGD
GPAGLVHASVRGLVRSAQSENPGRIVLVDVDADGDVEHALSAALASGESEVAVRGGVLLV
PRLARASVAGSDPEWAAGGTGTVLLTGASGSLGGLFARHLVAEHGVRRLLLVSRRGDAAA
GAADLSAELTGLGAEVSWAACDVADRDALAAVLAEIPAEHPLTAVVHTAGVLDDGVVGSL
TAERLSAVLRPKVDAAWNLHELTAGLDLAAFVLFSSAAGVFGGAGQANYAAGNTFLDALA
AHRRARGLVATSLAWGLWGEAGGMGDTLEADDVSRMARGGVTALTAAEGVALFDSACASG
QPLLVPVRLDLAALRAAARGGLLPPLLSGLVRMPSRRAARGGTAAGGAFARRLAALPQDQ
RPGAVMELVRGQVAAVLGFAGPEAVDPARSFSEVGFDSLTAVELRNRLAAATGVRLPATL
VFDYPNPAVLAEYLHAELLGGHGADVAAVAASVHDDEPIAIVAMACRFPGDVRSPEDLWR
LVADGRDAISAMPDDRGWDLAGILDPSRPGADYSPTGGFLHDAHHFDPSFFGISPREALA
TDPQQRLLLETSWEAFERAGIDPASMRGSRTGVFAGVMYNDYGTLLHRAPEGLEGYMGTS
SSGSVASGRVSYTFGLEGPAVTVDTACSSSLVTLHLAVQALRNGECDMALAGGVTVMATP
GTFIAFSIQRGLADDGRCKPFAAAADGTAWGEGVGMLLVERLSDARAKGHPVLAVVRGSA
VNQDGASNGLTAPNGPSQQRVIRQALANAGLSAAEVDAVEAHGTGTTLGDPIEAQALLAT
YGQDRPADRPLLLGSIKSNMGHTQAAAGVAGVIKMVQAIRHGVLPKSLHVDEPTPHVDWS
AGAVSLLESATPWPETGRPRRAAVSSFGIGGTNAHTIIEQAPEVAVVTAAETGTEPVLPY
VLSAKSADAVRGQAARLRRHLEGSAGLRSADVALSLATTRAVFDHRAVVVAGDRQELLRG
LTALEDGAAAAGVARGSVSTGKTAFVFPGQGSQWLGMAAELLESSPVFAARVDECAKALE
PFTDWSLVDVLRGVEGAPSLDRVDVVQPALFAVMVSLAEVWRSAGVRPGAVIGHSQGEIA
AACVAGILSLDDAARVVALRSQAIGRVLAGLGGMVSVPLPAAEVRERIAPWGEQRISVAA
VNGPSSVVVSGEVQALDELLASCEADGVRAKRIAVDYASHSAQVELLRDELAELLAPIAP
RTAGVPFLSTVTGEWVEGPELDAGYWFRNLRRTVELEQATRTLLEQGFGVFIESSPHPVL
TVGMQETVEDAGREAAVLGSLRRNEGGLERFWLSLGEAYVRGVAVDWDAVFTGTGAQRVD
LPTYAFQRDRYWIDVPIGQVGDVASAGLGSAGHPLLGAAVELPDSEGFLFTGRLSLQSHP
WLADHRAAGAVMLPGTAFVELALHAGRRAGTDSVEELTLEAPLVLPEQGALQLRLSVAAP
DEAGRRALHVHSRPETSGDDGGEGHGVPWTRHASGVLGAGGAAAAPKVSCPDVWPPVGAE
QLDVADLYEQFAAMGYAYGPAFRNLRAAWRGGDELFVELALSEGPQADAAHFGVHPALLD
AGLHGLALGSFLTGGDEEGDEGDRIRLPFSFTGVGLHAVGAGALRVRLAPAGSAGVSLTA
FDERGEPVVSVDSLLLRALDPTRLHAARPTFHESLFRLEWPATAGNPASPSGRWAVVGTD
TFGLEAALLEAGITADVYTDLDVLAGVVLAGKPLPDTVLVPYAADPAADTAGATREATHE
ALKLVQTWLAEETLAGARLVVVTRGAVEARPGEGVADLPGASVWGLLRSAQSENPGRFLL
LDLEAGPEGAAGGAAVGLAPLLAAAVAGGESQVAVRDGVPHAARLARIPAARPETDGADL
GAPAATLDPDGTVLITGGTGVLGSLLARHLVTERGARRLLLTSRRGPAAAGAPELVAELA
ALGAEAAVVACDAADREALAALLAGIPAEHPLTAVVHTAGHLDDGLVPSLTPERIDAVLR
PKVDAALHLHELTRDLDLAAFVLFSSAAGTLGSPGQANYAAANAFLDALAQRRRAAGLPA
VSLAWGLWEQRSEMTGDLTDADVQRMARAGLAPLSSAEGLALFDTACALSAPATGADAGA
DAAGEPGGPDGTVFVAMRLDTGPLRAQADAGGLPPLFRGLVRGGLRRAAAPGVADAAVSD
AARRLAGLSGLPEEEQERVLLEVVRATAAAVLAYPSPDAVGESQQFLELGLDSLTAVELR
NQLNAATGLRLPATLLFDHPTPLLVAARLRAELAGAPGGPAGPDGAAEQGGEEDAGVFGS
MLREAGTQGASGQFMELLMQASRFRPSFASAAELRKAPSLVRLSRGGTRPGLVCFSSILS
ISGPHQYARFASAFRGRRDVHAMAAPGFLRGEQLPSTAEAVIEAQAEAVLRHADGEPFVL
LGHSSGGMLAHAVAGRLEGAGVFPEAVVLVDIYSHDDDAIMGIQPGLSQGVDERQGSYVP
VDDSRLLAMGAYFRLFGGWKPEAVKAPTLLVRAQEQFFDWTRATDGDWRSYWDLEHTAVD
VAGNHFTMMEQHATTTAGTVEEWLDAHL
>A0A0H4W8M6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Bordetella hinzii|TrEMBL
MAKRVAIIGLAFRFPGTSTEQYWPDLLSGKDLITQVDPDRWSTDAYLHPDKDQPGTAYTH
AAGSLGDVSGFDADFFGISPREATLMDPQQRLLLEMSWEAMEDAGVKPSHLRGSDCGVYI
GISSADYAYRMSEDLNVVDASTATGNTSSIAANRLSYFFDLRGPSIAMDTACSSSLVAFH
QACRAIQSGECSHALAGGISLHLHPYGFIIFSKASMLSREGHCNVFDASGDGYVRSEGGG
IFLLKDYDRAMADGDRILAVVAGSAVNTDGRKSGLTVPNADAQIELMRSAYQQAGISPAE
LDYLEAHGTGTAVGDPIETRAIGAALGKRRPVSQPLPIGSVKSNLGHLEPASGVAGLVKA
IYSLTHRMVPATIGVRQLNPNIDFKDWNIEVVTQNRPLKPKGKLIIGVNSFGFGGSNAHV
ILESPSAVAETAATKLVKNAPVPLVVSGKTQEALRAAAAAMARRLRADTGRSLYDIAYHA
AQRRDWHDERALVFASDKQRAADDLQSLADGGASKYRVSTGTAVKDAKGPVFVYSGNGSQ
WAGMGQRLMSDPVFAAAVHEVDALFSEYSDFSPAAELSDSGGNDRHDRTEIAQPTLFALQ
VGITRMMAQRGVVPAATMGHSVGEVAAVWACGALSLPEAVKVIYHRSRLQGLTKGKGKMT
AVGINADETEALIAELKLGQGLALAGANSHRGATVAGDPALLDTLEAVLAERSIFHRRLN
LDYAFHSQAMDGIEHGIRQSLGDISPRDANLPFYSTVSGQRESGRKLDAGYWWRNVRLPV
RFETASAQAIADGFNVFVEIGPHPVLRGYLKDALNTADTAGSIFITASRGGDDPEKIHDV
AGQIILSGASVDWQALFPWKGEHTALPTYPWQREKYWHGTTSESSGLLMRQRVHPLLGYA
LAQHDGVWENRIDAQQFPVLADHVVGDATVFPGTGFAELALAAALQWLPGEFADIEELEI
RAPLILSGTKRVRVILDKDDGRLRIEGRDQNSADPWTLHATARILEETGSVPLRGDTVLS
LPARDPDFVEADHNRLTRLVGLQYGPAFRVISHGWLESADCALAVFQPEEALQGSLDGAL
LHPALLDCGFQLIIQLLKDDGAMGQGMAFVPAKIGRLTLHAAQGQVKFARARLRRRSPHS
LTADFDLFNAEGKRIASVREARFRSIRLRKAAGEHLDFVDCVLTPRPHPLAPLPASPIPA
DTLARDLRRLAQTPQEANNDRYSQEVDPLLESLCDRQAVEALRSQASGGHTLSAAMVERR
LRRHPAAAALFEHLLNRAVAAGAAQPSPTGWTFAPDEEGQPSAADIWNSLLREYPDYFPA
IYAAGRVGLHLPQLLRGAIDIEQVLPGIATPTAISRLVLGAERGQRLAGVVAQALRRARC
EPGQRLSMLEIAQDAPIFGPACCAVLDFDVADYRFASPDSQTVEDVRHTHLDSYPDASAE
WIGEDGLPGDEQRYDLVVLHCEFDTLEAARQALGYARACLKPDGKLLLRGTHPAQWMDFV
FGARASWRHADGTPLPQAGYWMQCLQELGLACEPLIEFSPGSQSGPYLILASAAQAQPQV
PAGEPRRQLLLASSTGPGAILAQTLDEQLRAAGQHSVLVKDVGPARLDALIKEARLQHGQ
LHDIVLLDGWGDDDPARDGDFDKQVRRCALAAAVIQACEHTDTSATVWIITRNAGVSMGG
GDAQSSAIADAALWGYGRTLANEASNYRVRLVDLPGDPKAVQALLREILHPDAEDEVLIG
ADGERYAPRLREVGRPAPAPTASEAKQACRLGFDFPGQLRNLRWEGYDAPEPADDQIEVR
IHATGLNFRDVMYALGLLSDEAIEQGFAGPTLGLEFAGEVTRVGSSVTEYRRGDQVVGFG
PASFGDRVLTRASAIAPIPNGISFEAASTIPSTFFTVYYALHHLARLEEGEKILIHGAAG
GVGIAAIQYAQWVGADIYATAGSEEKRDFLRMMGVTNVYDSRSLSYADEILADTGGIGMD
VVLNSLAGEAINRNLQVLRPFGRFLELGKRDFYENTRIGLRPFRNNISYFGIDADQLMCE
RPDLTRRLFGEMMQLFAEGALHPLPYTIFDANEIVDAFRYMQQARQIGKIVITYRNGLRY
LHQASATEARHLRLPDDASYLVTGGLGGFGLRTAQWLAEKGARNLVLISRSGPASEEARA
GIAALAASGVRVHAAACDVTDARAMEQLLADVARDMPPLRGIVHAAVVIDDGLARSASAQ
QIASTMAAKVKGAYHLHALTRGLPLDFCVYYSSATTLFGNPGQSNYVAANMWLEALAAHR
RAQGLPATCVRWGAIDDVGFLARNEKVKDALQGRMGGSATASAVALDALETLLLTQSSGL
GVLELDWKSLARFLPSSDAPKFSALARHGADSAGDDDHGLDIAYLLATQDDTALQHIFGD
MLKTEIGEILRVSADKIDPERSIYDMGLDSLMGVELIVALENRFGIRLPVMALSESPTVN
KLAARLIELLRGEQQSCPQDALSSTIGKLVSDHAAELSESTITEFVDDIKNGDATAPKRM
IP
>A0A086PSR3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii VAND|TrEMBL
MMTRLPLCQQQAPPSLAGCHMLAAFQDIPERPLNRDLKELWAAYGENPFGNVLECWNRSI
PDEDAVVWLNSDGEISETTTFSELFSRITRLSSFLRAAGLQVGDRIILCYPPGTDFVTAF
FACITSGFVAVPVYPPDPSKGLSDVPRFCDINEIAGCKTALTNSLYKRVVQVITTVAKDS
RWRSVHWVCTDDVIKRHAEEAKNSVGPDFPNLSPHHPAFLQFTSGSTGNPKGVIVTHGSL
LHNCHLCWSAYQFPSHYENDGDDENITNHDFALVNQREFWRRRQEISIKSRGHRLRAFSW
LPVYHDMGLIGFVCSPILCGATLYQMSPIDFIRRPWLWLQGMSKYDCICCAAPNFAFEVV
TRKMPDNVYEHLDLSRVCGFLSGAEPIRASTIDRFCEKFGPKGVRRCAVCPAYGLAESTL
IVTARKTFQTVPKLLIVDSFQLQHEKTVVALTPEATVTMDSEEYQVLVGCGVPLEGVQVR
IVDPETKKELPPGKVGEIVVYSSSVARGYFGRPDTTKETFCYSFTDLQGKQTPPLGMRTG
DGGFMYEGELFVAARLKDLIIIRGRNFYPQDIEEAVDKVAMVRPGSSAAFAIEVDGHEAL
AVAAEVRLEEGIKGLWLRVKRQFDRSHYEQIVRDISKSVAANTGLTIHRIWLLRPRTIPK
TSSGKVRRSLTKEKLVSGKLEGILLDHAHHQHQAFYHDGPGSSRSRTRTGSGATPSGGAA
TRDGTASSNPSGDAHPKNSNTSNSITDSSHSVQRGSLRGDACVAGGRLGPSASHGGVHHE
KDHKHRGDGSGMSSPDQVPGAGAAASESSAHAALTEKVKQTVFEAAKTVLGSSEIPEIDA
PLHELGVDSIGAVEFSELISAELQVDVEPTLLFNYPTLSDVIDFFVRELEGKGSEDLAVS
LEKTGARETTTAIIGAACNLPGGTTSLNAFWDLLMCGVDAIAEVPRSRWDVEEYFDPDPG
ADGKAYVREGGFIEDAEMFDAAFFRISPSEAKSMDPQQRLLLEVAYESLYDSGYTREGLQ
RASVGVFVGCCSNDWYQVCSQLELGISSYTTTSYAPSIIANRLSYTFGLLGPSMTIDTAC
SSSLVALHIAAQELQGGSCMSAVVAGVNLMLSPHITVAFCKSRMLAPDARCKTFDASANG
YVRGEGLGSIVMKRLSQAEKDDDRILCILRGTAVNHGGRSASLTAPSGPSQQRVIRTALR
QAELTPGDIYFVETHGTGTSLGDPIEVGALKSVFGASRDAKTKPLILGAAKTNIGHLEGA
AGIAGVLKAMLALRYKHIPPNLHFKQMNPHIDVREFNVVVPTAPMAFPREDGGRLFAGVS
SFGFGGANGHVILQEALQQPSGDKPPCKRHSKRSIICFMFTGEGYEVSCMGRHLYETDDV
FKEIITKCNDILKRWLNVSLLSILYPPADKKMEMDKMMCQARFGHTALFAFEYALAESMV
SKGVKPDVVFGVGLGELVAAAFSGVMSLEEALYVVTQRAKLIDNLPPFEGVMVACRVSEQ
EVEMALSEMEINSRQSISIAAVYGRKNLILSGEQSEIDNVLMKLNIAGRWKYLPVHNVLT
MNLVSDIIPPFTHLMSTVKLCRPKVRLVSSTTGEFVDKEALSGRFWSRQVSQTVQLQQAV
GNIVASGCSLFVEIGPQVVLTKLAQQSLNGNAKDVTWVPAYDTTSDDVRVFENAVMTCNE
AIKIIGKERSLEEGQHGQEELIFHRKPFPWTEIPHPFLSGHKFTEKDDVVFENAFPRRAI
PLIADHAVNGTAMMPGAGMLEMVGAAALALDLRTTSGAVSLENISFERPMLIGAHRVTYE
YNRRHSLGEGGGAGTSPRTVRTPRLVNHAYTRLGFREKSAEKAISETAGPASTEGGRTPV
AGHHHGSYTKAGVLEDIKDYAHNVLRRAAQHAEEIDVHTPVPPSMAPPSIVARHPREGSY
GSMSRTSGIMGSNDRGDGLTVPLSVEMAIRCRVTKMKEVELSTVWDDEVTDHCFATIVIA
DKKQETYSSLQEVRCRCTERMDVNEYYDMLYDAGLQYGPRFRTIQELYRGEKEALARVHF
VGNVKQDPFESGFLIHPAVLDGALQAAGCLLEQSHSGNKVMVPVSVGSATLTKVEVFQPC
WAHVRLEETKSKAATLNVTIYDEVTREVVASLQNAVLRQVDPSASVVATIPKELLWKVNW
QLVVDGDKEVVGRTPKVLFIGGNIELSEALENAMGSTCKTLSVDALPREKAELQKVLDAE
QWQAIVYVEAVTAGVYDALDVMNAAVRLVQAHYLNLNSGKAVGALWFVTRDTVFRDNGAD
KPGVEIPAHAGLWGLAKAARLEMEVSAGSPISMGCLDVSGADVSSMAQQILHALKSKVLT
MRETEVAVREDGLYVSRLAPQTEVDVRGAIEFHMPERGAISNLVLRPQAFASRLPPEDGQ
IELRVRAVGLNFRDVLNVMGLYPGDPGPPGADCAGVVVAVGDNVEHIEVGDCVFGVAQGC
LRTYVTTDSQLLRRMPESMTFEQAAALPVVATTVEYALHDLAKVKAGDKVLIHAVTGGVG
LVAVQLCKRVGATVYGTCSGGKKDAFAKSMGVQYVSSSRDAKAFAEDMRTFLGEDGKVDV
VLNCLIDDFIPESLKLLGPYGRFMELGKRGVWSKEKVAAERPDVQYELIAVDEMMEKDPI
WFGGMLVRVRGLVAEQKIQPLPMHVFDLADTGENGGVAAFRFMQRAQHMGKVVLKIPSPV
EEASKNGSIVITGGLGALGMVVAGWLAEEGARHICLLSRREEAPQPGEIPGWDWLRTINC
DVQFFSCDVSKYDSIRSVLRTIQTSVAPITGIIHTAGALADALLDSQTPELMKKVYNGKV
QGAWNLNRALEELGLNEQLKLCVFFSSVTSLFGNFGQANYCSANACLDALAQWRRAKGLC
CQSIQWGPWIEQGMAAELKQQVERNGMKGISNEVGLRVLHDAIRQQEKATPVIGCQAIKW
KLFMHRYIEQPPFFTNIEMDLQVTSHDSNTVLRNLPPSERRDYIKAQVAAAARQVLGSSS
PPPFDTPLQDVGVDSLGAVEFRNVLSKKLGVKLSATTLFDYPTLNAIIDHLCEVFGESSQ
KDSLSTKLGALSENDLVQEGMAIVSMSCRLPGNSTCPDLFWDMLMRCTDCVCDIPLTRWN
AEEVYSEDPDLPGKCYTRRGAFIENAEYFDNSFFGISPSEVKHMDPQQRLLLEVAYEAFA
GAGLTKEKLLGANIGVFVGACNHDWTYLIQEDKISAYTGTGSAGSVIANRVSYCLGLRGP
SVPVDTACSSSLVAADFAFEKLMLRDCTMALVTGVNLMLTPHLFIAFSKARMLSPDCKCK
TFDASADGYVRGEGAGAVLMLPYADAKAKQMTIQAVVKGTACNHVGRSASLTAPNGPSQA
EVIRMALRRAGMKPNDLKFMESHGTGTSLGDPIEVNAVRTVFAPGREKTKPLLIGAVKTN
IGHLEGSSGIAGLIKACLVLSRREIPPNLHFKTLNPHINIEDFPVQFVTDFVSLDSVEST
RKKNTAGVSSFGFGGVNAHVLLEEATRDQNATRKEENRPKICFMFTGQGSQYVGMGRHLY
EKEPVFREAITRCVEIAKEYLPLPLLSVIYPSPDERDKMQEAINETLYSQPAVFVISYAL
LELWKSRGVEPDMVMGHSLGEYIAAVCSGVISIQDGLKLVLKRAQIMSRAPSRNGVMVAC
RATAEQVEEAIHTLFGDGEKNVALASVNGLKSVIVSGNQQDVQAVLRQLGAASRAKMLRV
SHAFHSPLVKDTVAPFKRVLETVRLSKPRVMFVSTVTGKVARDELQNTNYWAEHITKVVR
FCDAVQACIAQGAKIMVEVGPRPTLSNMGKGCLPQTTADEVQWINSLEPETLSSAVFDSL
SALAKAGSGAMPAVFDRKFFPWTETCHPLLGGKNTRPDGSVVYSALLRDLVKALFLDHVV
YGKALLPATCLIEMMASATTHMISNHDEEKLVALSQVVFEKPLLVPDDTSLSVLVTVETR
GQVRVASQVSNSEEEAEDHAVCQVNIVDALPAAPALTEIRARCKTEIEASQLYAQLHNVG
LQYGPRFQTIVKVFKGEDEVLGLLQAQNVTNFETGFMMHPAVLDGALQLSAVLAFEKGSS
RAMVPFGVDTVLLKSCPPEKELWARVVMNRKGVSSASATVHLYDFDGEPIAVLMGVTLRP
IEFNTAADIPRELLWEVEWEYAGSYSMPQDGSLATPSGTDDSGAEDVTRTPSPLVTGENE
NTPSREVPSALPGLSTETPRASKPLSTDETSGAVLNKSVHSVLLVDYAGGHREAVASIRD
TCDVEVEVLSKPGSPELYAQQLRQFAEVVATKTETVPLSTILFLALDEATPAEQLAGGLL
ETVKVFAVEKFKKLPCIWVLTSGAQGPTRSVVSPKHAGLWGLMRTVRLELEMQIGKMVRF
GCVDLDKNLEVSVALHFILQKRTEEPFEAEMILRCPSEDSEKEPGTAEVVNRRERSASFV
SVGPEPVVPSTTDASAKSSVTSDRMALTPGALSCFDETANSTEKLIFNAFCPRLHRSPIP
VRGAVELHMPERGAISNLVLRPQAFASRTAPQSHECEIRVRAIGLNFRDVLNVMGLYPGD
PGPPGADCAGTVVAVGSGVRHLKVGDSVYGIAQGCLRTYVTTNGNLMRRMPESLTFEQSA
ALPVVASTVEYALHDLAKVKAGDKVLIHAVTGGVGLAALQFCKRVGATVYGTCSGGKKAA
YAKSLGVKYLTSSRDASAFAEDMREFLGEEEKIDVVLNSLIDNFIPESVKLLAPGGRFME
LGKRGIWTKAQMAAERPDVYYETIAVDTMMQEDTVWFGGMLDRIRDHVDSGNIPPLPLHV
FEMTDPLAGGVAAFRFMQRAQHIGKVVIRIASDLEVKIPSTTEPAATETAMLAEAGTQGN
ASIGTSTQQIADRT
>A0A1Q2ZQX8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MRKALALSGVQPGGESALRRRLAGLGERERARALLDLVRREAAVTLGFDNADALPDGRAF
RDVGFDSLTAVELRNKLASATGLVLPASLVFDYPTPAVLAEHLGSELLGSEAQVVAPAVV
KAEPDEPIAIVGMGCRFPGGVSSPEQLWDVVASSADVVGEFPGDRGWDLTGADFARVGGF
VEDVAGFDAGFFGISPREALAMDPQQRLLLETAWEALERAGIDPDVLKGSRTGVFVGGTV
SGYEAVGGASGDAEGYMLTGGAGSVLSGRIAYTLGLEGPAVTVDTACSSSLVALHLAAQA
LRSGECSMALAGGVTVMATPRGFAEFAIQGGLAADGRCKPFAAAADGTGWGEGVGLLVVE
RLSDARRNGHQVLAVVRGSAINQDGASNGLSAPNGPSQQRVIRQALASAGVAAAEVDVVE
AHGTGTRLGDPIEAQALLATYGQDRPEDRPLWLGSVKSNIGHTQAASGVAGVIKMVLAMQ
QGVLPRTLHVDEPTPEVDWSVGAVELLTEQRSWPVVDRPWRAGVSSFGVSGTNAHLILEQ
APELEPASGMEVEPVVVPSVVPWVLSARSESALREQARRLAAHVEADPGLDPVDVGAALV
STRANLGHRAVVLGADREQLIAGLAGLAAGEPGAGVLTGVSVAGGRTAFLFTGQGAQRVG
MGRELAAEFPVFAEAFGEISAGFEGLLPGSLEEVVFGGDEYRLTETGWAQPALFAFEVAM
FRLLGSWGVAPDFVVGHSVGELAAAYVAGVWSLPDACRVVAARAGLMQALPAEGVMLAVE
ASEAEITSVAGEVAGWGERAAIAAVNAARSVVLSGDAAVVGAMGELWSGRGRKVRRLRVS
HAFHSPLMDPMLGAFADVLGGVEFNEPSVGMTVPAAQVCSPQYWVRQVREPVRYADMLTE
LSTQGVTRFVEVGPDGVLSGLGSGAVDGVFVAAQRRDRPEVHTAMTALSTLHTHGVPVDW
PAIVGRGSAVELPTYAFQRERYWPEAVAGPVVAGADDELWSVVEGADAGLLSAELGVGEQ
ALAEVVPALAAWRERRRSRFAVEGWRFAESWKLLPGAPGGALPGSWLVVVPVGWGEDAWV
ASVVGALGVGVVRLEVAGDADRTVLAAVLADLPELAGVVSLLGVAEQACPGFGATPVGLA
GTVGLVQALGDCGITARVWCVTRGAVSVGSADPVGSPVQTALWGLGRSAALDLPVRWGGL
VDLPVAVDERIGGLLRRVLTGDEDQVAVRESGVYGRRLVRAGSSGAAGAEARLNGSVLIT
GGTGGLGGHVARWAVARGAEHVVLVSRRGEQADGVSGLREELIAQGARVTVEACDVADRE
ALAGVLARVPADCPLTAVVHAAGIGDGHVPVGELELGRLDGVLRAKMVSAWHLHELTAGL
GLEAFVLFSSGAASWGAGGQAAYAAANAFLDGLAGYRHGAGLAATSIAWGLWAGPGMGAA
GAEFVEGYRRRGVLAMEPGLAMAALERAVGDGSVTLTVTNTDWETFAPSFTVERPSALLS
GIPEVRKALALPGAGSVGESALRSRLAGLGERERTRALLDLVRREAAITLGFDNADALPQ
GRAFRDVGFDSLTAVELRNKLASATGLVLPASLVFDYPTPAVLAEHLGSELLGTVEAVSV
MPVTTVAVDEPIAIVGMGCRFPGGVESPEQLWALLAGGVDAVSAFPTQRGWDLVGDGFAR
VGGFLYEAAEFDAGFFGISPREALAMDPQQRLLLETAWEALERTGIDPNTLKGSRTGVFV
GGTGSGYDTVGGASGDAEGYMLTGGAGSVLSGRIAYTLGLEGPAVTVDTACSSSLVALHW
AAQALRSGECDLALAGGVAVMATPGIFAEFAVQGGLAGDGRCKAFAASADGTGWGEGVGL
LVVERLSDARRNGHQVLAVVRGSAINQDGASNGLAAPNGPSQQRVIRQALASAGVTAAEV
DVVEAHGTGTRLGDPIEAQALLATYGQDRPEGRPLWLGSVKSNIGHTLAAAGVAGVIKMV
LAMRHGQLPPTLHVDEPTPEVDWSAGAVELLTEQQPWPVVDRPWRAGVSSFGISGTNAHV
ILEQAPELEPAADAVAVPSVVPWVLSGRSESALREQARRLAAHVEADPGLDSVGVGAALV
STRAELEHRAVVLGAGRDELIAGLAGLASGEPGAGVVTGRAGQSVAGEQGVVFVFPGQGS
QWVGMAQGLLVSSPVFAERMAECAQALAPFVEWNLLEVLGDEEALGRVDVVQPVLWAVMV
SLAQVWQSLGVTPAAVMGHSQGEIAAACVAGGLSLADAARISAVRSRMIAGSLAGRGGMV
SVGLPRAEAESLIARWEGRLSVAAVNGPSSVVVSGDPEALAQLVVAGGEENFRARKIEVD
YASHSAHVEEIRAELVEALADIVPVEGTVAFYSTVTGELTDTRDLDAGYWYRNLRETVRL
ADTTRALAAAGHGTFVEVSPHPVLTPSLEETLFESHPSAVVTGTLRRGENELEQLLAAAA
RLHTRGVPVDWSEIVGRGSVVELPTYAFQRERYWPRPRAVAGDVRGAGLTSVGHPLLGAA
VELAGGEGVVFTSRLSLTSHAWLADHTARGVVLLAGTAFVELVVRAGDEVGCGVLEDLAL
ERPLVLSEREAVQVQVVVEAPAESGRRAVSVYSRLEETGTEAGWTRHASGTLTSEQTMPS
GAELTVWPPAGAEPVPVDDLYNGLAEAGYGYGPSFQGLRAAWRRGEEVFAEVRLPDEVAD
SAGEFGIHPALFDAALHAAAFLPAGGEGGLPFSWSGVSLHASGAQSLRVRLSVAGDGGLC
LNAADDTGAPVVSVDSLVVRPAPQGQLSSPGSGQDNLFSVDWIVKPESGGSLPRCVVAGA
GGQDLAAMLGVPWHSELSECQDADLVLLPTGAGADGGDVVAAARSEVCRVLGLVQQWLAD
ERGDTRLVVVTRGAVSTGTGDRVEDVAGAGVQGLVRSARSEHPGRFGLVDVDGSAESWQC
LPAVLNGTADDEDGFELAVRAGQAYTPRLTPTRTREVLAAPEGVEAWRLGMAGQGSVDDL
VIVPSPEAEVPLEAGQVRIGVRAAGLNFRDVLNMYPGEVPVLGAEVAGVVLEAGPGVTGF
LPGDRVMGMAVGGFGPVVVADARLIVPFPQGWSFVQAAGVPVVFLTALHGLRETGRLTAG
QRVLVHAAAGGVGMAAVQLARLWGAEVFATASPGKQDTVCGLGVARDHIASSRTTEFADR
FTGMDVVLNSLAGEFIDASLNVLRAGGRFVELGKTDLRDTDAIATTHPEVNYQAIDLTDF
SPDMVGGMLAELAELFESGVLSPLPTRTWDVRQSRDAFRYMAQARHVGKIVLTVPQQLDP
DRTVLITGGTGGLGGLLARHLIDRHGIRHLTLVSRQGITAPGARELVEELTGLGAEVRVV
ACDVSDRNAVAELVAGVPQQHPLTAVIHAAAVLDDGTITSLTPERIDTVMRPKADAAWYL
HEATAGLDLATFILFSSVAGVFGGAGVAGYAAANSVLDAMAQQCAARGEPVVSLAWGLWG
DAGGMMGRLGQTDLVRFGRAGVRAMPAAEGLALFDLACRRPEAHLAPVGLELSRHNEPVL
PLLRGLVSAGGRARPVARAGVQDGSGLAGRLAGLTADDQQRLLLDLVRGHVAPVLGHASA
QDIEPDKAFRDMGFDSLTTVELRNRLATATGLRLPATLAFDHPTASRLATHLRQRLTDTV
EAVSVTPVTTATVDEPIAIVGMGCRFPGGVESPEQLWTLLTGGIDATSAFPTQRGWDLTG
DGFAQMGGFLHEAAEFDAGFFGISPREALAMDPQQRLLLETAWEALERTGIDPNALKGSK
TGVFMGGTGSGYDTVGGTAGDAEGYTLTGGASSVLSGRIAYVLGLEGPAVTVDTACSSSL
VALHLAAQALRSGECDLALAGGVTVMATPGVFAGFAMQGGLASDGRCKAFSVTADGVGLA
EGAGLLAVERLSDARRNGHRVLAVVRGSAMNQDGASNGLTAPNGPSQQRVIRQALASAGV
TAAEVDVVEAHGTGTRLGDPIEAQALLETYGQGRPADRPLWLGSLKSNIGHTQAAAGVAG
VIKMVLAMRYGQLPPTLHVDEPTPEVDWSAGAVELLTEQQQWPVVDRPWRAGVSSFGISG
TNAHVILEQAPELEPASDAVVVPSVVPWVLSARSELALREQAWRLAAHVEADPGLDPVEV
GAALVSTRASLGHRAVVLGTGRDELIAGLTGLAAGEPGAGVVTGVAGSGGRTAFLFTGQG
AQRLGMGRELVAEFPVFAEAFGEVCDGFAGLLPGSLEEVVFGADEHRLTETGWAQPALFA
FEVAMFRLLSSWGVAPDFVVGHSVGELAAAYVAGVWSLSDACRVVAARAGLMQALPAEGV
MLAVEATEAEIASAAGEVAGWGERAAIAAVNAARSVVLSGDAGVVGAMGELWSGRGRKVR
RLRVSHAFHSPLMDPMLDAFADVLGQVEFNEPSVGMTVPAAQVCSPQYWVRQVREPVRYA
DMLTELGVQGVTRFVEVGPDGVLSGLGSGAVDGLFVAAQRRDRPEVHTAMTALSTLHTHS
VPVNWSAIVGRGSAVELPTYAFQRERYWPRSRAVAGDVRSAGLVSVGHPLLGAAVELAGG
EGVVFTSRLSLASHDWLADHAVRGVVIVPGTAFVELLVRAGDEVGCGVLEDLALERPLVL
PERGAVQVQVVVGAPAELGRRAVSVYSRPEETAAEAVWTQHASGTLAAAGVPAPVWQDVA
WPPAGAEPVPVDGLYDGLAEAGYGYGPAFQGLRAVWRRGEEVFAEVRLPGEVADRAGEFG
IHPALFDAALHAAVFLPGDVEGGLPFAWSGVSLHASGARSLRVQLSVIGDGALRLNAADD
TGAPVLSVDSLTLRSVRAELLESGSGQDNLFSVDWIVKPESGGSLPRCVVAGAGGQDLAK
MLGVAWYPELSECQDADLVFLPTGAGADGGDVVAAARSEVCRVLELVQQWLADERGDTRL
VVVTRNAVSTGTGDRVEDVAGAGVQGLVRSARSEHPGRFGLVDVDGSAESWQCLPAVLNG
TADDEDGFELAVRTGQAYTPRLAPASVGEAPEARPVDPEGTVLITGGTGTLGGLVARDWV
ERHGVRHLLLVSRQGTAAPGARELVEELTGLDAQVRVVACDVSDRAALTAVLDAIPDEHP
LTAVVHTAGVVDDGMVTSLTPARVDAVMRPKADAAWYLHEATAGLDLAAFVLFSSTSGVL
GAAGQAGYAAANSVLDAIAQQRAARGEAAVSVAWGMWAPASALTGQLSQTDRRRISATGV
VPLTAEEGMVLLDRAVRSGRSFVAGMRWDPAGVRSGQPLSGLLRGLVRGPVRRRSLATER
DGEAAGAALRQRLAGLSAADAHAVLAQVVTTHTATVLGHATPESIQATSAFQELGFDSMT
AVDLRNRLNTVTGLRLPATLVFDYPTPDTVAGHLRSELRPDILAAEPSGDTDARLGETLA
TIPVSRLRKAGLLDLLLQLAGEDGEVAQNTTSDDEISIDELDGESLLRLAAENTTN
>A0A100JD90|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MPATPSDLVRPLPELLRGHAESRGTKVAFSDSRTSLTFADLDLRTARLGGHLAALGLPRG
SRVAILLGNRVEIVESYLGVNRAGCVGVPVNPHSSDAELTHVLTDSDALAVITDTAHAAQ
VRTALPPGERHVIVVDESYEDLVTRDPATGPRDDLGLDEPAFLLYTSGTTGLPKGVLSTL
RAVLWNVTTCYTPIIELSPDDTMLWPLPLFHSLGHNLCVMAVTAVGASAHLVPGFSAAEV
LDELRARPYSFLVGVPTMYHNLVHAAGTEGLQLPALRVCFVAGAVTTPQLAASFEAAFGV
RLTDNYGCTETSGPMATMRPGGEPRPGSCGLPLPGLDLRVVDPETGADVPTGAEGEIWVK
SPNVMLGYHNRPDATAEALKGGWYHTGDLARRDDDGYLYITGRRNNVIIRGGENVHPTEI
EAVLFKVPGVREAAAIGVPDEEFGQVPVALVVPGPDGVDCADLFARCRRELAYFKVPVEV
RAVRELPKTATGKVIRRLLPDLPGRLLGVSGVHEGLQLVGTGGELTSLPGTEPLPSLAGR
EVAVTGGRLADLIAGHLVEGHGARRVTGDQYDLAVTVTGTTVTVAGTTLVLADGLTDRRV
LDALDVALGHPGATLVTAVRSAAPERLPEKADLTGTSLVDVITREVTHVLGDPVGIEPDR
ALREYGLTSADAVRLRDRVAAAVGLRLPTTLVFDHPSVRAIAAYVHGELTGSTETLAPTA
VHAAADDDPVVLVGLACRYPGGVTSPDELWRLVADEADAISGFPDDRGWDLERLFATSTT
RRGGFLHDAAEFDAEFFGISPREALATDPQHRLLLETAWEALERAGVDPTALRGERVGVY
AGLMLHDYISDMERVPRELEGYLATGVQGGVASGRIAYTLGLRGPALTVDTACSSSLVAM
HLAAQAIRRGECDLALAGGVAVMGTPQGFLEFSKQGALAEDGRCKPFAAGADGTGWAEGA
GMAVLERLSSARRAGHPVLAVIRGSAVNQDGASNGLTAPSGTAQREVIRLALQDAGLGPD
DVDAVEAHGTGTRLGDPIEAGALLATYGQGRSAPLWLGSLKSNLGHTQAAAGVGGVIKVV
QAMRHRTLPKTLHVDAPTPHVDWAAGDVRLLTESMPWPERGRPARAAVSSFGISGTNAHM
ILEEPPQEPAPTAAPEPEVVALTLSGKSPERLRDWAARLLPVVETASPGDLAHALAGRSR
FPHRAVVVGGELASGVRALADGKSAANVVSGTADVDGKVVFVFPGHGSQWVGMAAGLMGQ
SVFAESILACERALAPHVDWSLTEVLADPERLDRTDIVQPALFAVSVSLAALWRAHGVEP
DAVLGHSVGEVAAAYVAGALSLEEAARVVAVRGQVIAGLGGGTGMVAVPAPREQVDWLVE
RWPDQLWVAGLNGPSATTVAGDEIALKGLLAECALDGVRARRVRVGYASHSPRMETLREE
LLAQLGSVRAGTPSVPMYSTVDLEWVGSGALDAEYWYRNLREPVRFQPAVERLAADGFRV
FVESSGHPALTSAMEETLAGVGVNAVVTGTLRRDDGGPARFLSSAAELYVRGVDGVRLTP
PAGRAVALPLPTTPFRRRRFWLTTGGAARTRSGHPLLGAVVESARSGESVATSRISPVDL
PWLADHAVNGTCLLPGTALLDLALRAGGGGVDELVIEAPLVLSRQGVTELQVVVDGERRT
VEVYSRPDQAGARWRRHAQGTLCAGGVEPSGVAELVPSDAVKVHVDYSALTSLGYEYGPA
FRGVRRVWRRGAELFAELRLPEESPGGLGGVGLHPVLGDAALHALVFTDDSAEGEVRLPF
VWRDVWAGERQETEAYVHLVPSGASEVGVSIFTVAGEPMFRGTLGMRAVALRELTGAVPT
DSVYRMRWAELAGPVGEAGAEPVVFAPPAGDVRKAVLDTLARLQQWLEGEQDAPLAVVTQ
SGDLAHAAARGLVRSAQAEHPGRFVVVETDGDARSSARIGDAVGAGEPHVRVGAGRLQRP
ELARVAPGRGERPSLASGTVLITGGTGTLGSLLARHLVSEYGVRSLLLTSRSGGGEALVE
ELRGLGASAVVAACDAADREALAGALSLVPASHPLVGIVHAAGVLADGVVTGMTADQVEE
VLRPKVDGVLNLHELTKDADLAAFVLFSSVAGVLGSPGQGNYAAANAFLDAFAEHRRAEG
LPVQSQAWSFWEEISGMTSAVRDRDFPDGTLPLPTPFALALFDEALRQDEAALTLAKFDL
AKLRTRGAPGLLRGLAPARPATAPTVALRDLPPTERAAQLLTEVRAIAAELLGHADAEAI
SLDRSLHEFGLDSLTAVELRNRLSTLTALRLPATLVFDHSALRGLAEHLNGELTAAMEAE
V
>B4CW23|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Chthoniobacter flavus Ellin428|TrEMBL
MSDADAPPNLEGIALIGLAGRFPGARNARELWKNLAGGLESVAHFSEKELRASGIPEDLT
RNADYVPTRATLDDADKFDASFFGFTPRDAELTDPQHRVFLECSWHALEDAAIDPERYKG
SIGVFAGASLNTYLLDNIASHREQLADFVAQFQADGYPLLIGSDKDYLTTRVSYKLDLRG
PSVTVQTACSTSLVAVVQAVNALLSYQCDAALAGGVSITFPQARGHLFQDGAILSKDGHC
RAFDADATGTVFGHGCGVVVLKRLADAVADHDHIYAVIKGAALNNDGAGKVSYMAPSVDG
QAEVISLAHALAGVSAETIDYVEAHGTATPLGDPIEVAALTQAFRATTDKRGFCHLGTVK
SNFGHLEAAAGVTGLIKTALAIENAQIPASLHFQHPNPQIDFVNSPFEVVTRLTTWERKE
HPRRAGVSSFGVGGTNAHVVVEEAPSAPSDEIVSDGPQLLVLSAKTRYALEEATTQLGQY
LKAHPQVALADVAFTLQMGRRAFEHRRFVIANKTAEASKLLLRRDRQALYTSPLPGKPAD
LAPAEVSTNKLAAIGWKWLHGEPVDFAALHEGTSTRRISLPGYVFEKKRFWIEPDRSTPA
APVAAPVATAQPAAAAAAVEEPVAPVILSPLDDLKAFLKDQSGIDLAAATPTTSLLELGF
DSLFLTQIAIALQRRYGLRITLRQLLGELADLGPLAAYLEANRSKTPTATPEAPAAAAAL
TSGMPSAPAQHGPFRPLQKGSRAGVLSKTQQTWLERFHPPLQRAHRLLQKAHAGASCPLR
RPARSRRLQAGLEGDGLSHCRQSLPRRAPLGRRRQRLRRHHARLRSRPLRPPTGVCHAGH
RRADEARHGNRPEPPARWRGRRAALRNHRTRTGDLLQHGFGSGARRDSYRPHGHRP
>A0A6N3G7U2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Klebsiella oxytoca|TrEMBL
MDRKSIISGYSVHLPFADDSSQLIANLKQGKRVKTAPWFKSNDEAIKCGLRGNVNAAKMK
YSNDSIPELLYRLIDEALKQSMLDENCLREENIRVYITGIGPRVDAIDYRSFATYNDIED
LALTPSITNLCARNMSQDIIAELLAKKYRLRYLPPNINCTSNSGLTAVHLASHAIERGGI
ELALIINISQIKSQDIWFLSTQSMLDTDLVQPFGVNSKGVIFAEGYSVLVLESDHHRLAR
QLVDGVSIKTAYKQINASRSNDVYWQSTCILKLVNQLLNDTRVKIEDVCAFIPHGNGTAF
SDSIEAKAIAILAGENMLPVLAYKGQIGYTATGSGLVDLIIGHHSVSCHELIKSVINEPI
VNGIAHHFLTGPGVIKHHKSHLLKTGLGVDGSIIAALLSNTAREAS
>S7W5W8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii (strain ATCC 50853 / GT1)|TrEMBL
MEQKQEDSASTSKSEVNKSLVESLSTAKGARHTDDGFIFTNGQQNLHEAKKDQHGTSDST
LAEPVSNAILDPITRVTDALLVTADGTSVHKDEEELSLVAECFACVTGVEKSCLRPDTPF
LSLGLDSLTAVELANEIQRRMKQPVEPFELFEFADLRSLALYLRNKKLDHGKDARGRQTK
SSPERSLGIVQVQRPSVFVTGVACALPGSCQTPDKLWEILDAGIDCVGPIPPNRNFCASQ
NFAVIGEPRTANASFCVTEGGFLDDVDLFDNSFFGIPDAEAMTMDPQQRLLLMKAVEALH
AAGMATIDSRSAPIATFVGCCSTDWQRMNLGEQIQSFSATSHSASMLSNRLSYTLGLTGA
SITVDTACSSSLTALHCAMQELQHRHVPCHTAVVATVNLLLTTDVTLAFARAGFLSPTYR
CKTFDDAADGFVRSEGVVVFVLQTDVSETPTPNFKNQQEDNEGGQGECGTRIPASGYLCR
ILASTVVHGGKTGSVTAPSGSSQELLYKQTFACAQVPPRAVDLVETHGTGTRLGDPIEIS
ALCNSFAPDMETRKHRLVLGALKTNLGHLEGASGLAGLLKSVLCLNRQRVPPNLHLRKLN
RFIDFRSLPVLLPTKTVPLPASSSETKDAVALVTSLGFGGTYAQVAVQVPSTTGNEMLLR
NQETVQWNKKCFDVGKLVSQSNSFQSAVSHNDTKGPCFWEVGWEFLLEFDSITLTLPTLP
EQAPPAKWLVLTSPKAQQSFRKFSVNIFLPGIRMTFACLEELKAPEHLEAILKAETWTAI
VSTYTTETGSCMTDSSDLIGRTLQILQTYGQMASQSAVLPRLLFLTQGCFQVGAAASLLR
ASPYNAGIIGFVRACRLEIESLSGRKAPIYLIDFAANGTLTETLSAVSKLLGMIDIRNVD
ETEFAICGKRVFAPRLLPLHLGLEEILPAYDHYMDLTKKADESPAGTAKFPRLVEPANKA
CRVRLLALCLDEIFPIEAISPASKAFELGESRPCTLPYGYRNRRQKPSCTKWNERSYSHR
RIRYELPLCWLNRNKANVYFNQKRLGQSTCIFIEVILKLAVRFILPACFTKKMNAAPPST
ARENRPLYSALSDLKGLAFLCCAPGPDNASSLCGCSGILLEHGADSQHLTVGNVVCGIMP
RPHCEIVDIPGILLHPSPPSFSCELAASLPPQLALLLWALNQAPPLVTPPAKRVSRVLIV
GAGCGVGLVAATHFQTLGLKTFAVVCTEEQVEALVHYQFPHAAIWCYDRPDLRSALRREL
GYSSIDMVVWALKQEIDSSNNHLLNLLKHGGSFVDLVACHPESRLGWRLDVKYVHCTLDL
AARPYHAKEFSKNLALSCEILRQKTASQRQQIMHVFFDHAHRLGQHCSLASVQMTEAATP
QNVTSPADLSKQNVSFRPGVNAVEFVSGYSHAGSVVCSLPSPIFFNKASSSNGNCESNAS
TASSSAALGTEASSNVRTGTVLIFDCGSGNTWQHLRQWLSDEGASHIVVVHACAEEGADT
LGVKTLHPSRVNGGQGCSQTLIKEVKCRPHHPEEVVELFKLLKEGLHFPLVRGIFYILGE
KLDSLLANQTTSSVHDMMKTASGAWSIHHALGQLGMEADLDFFIFFSSISALFGSISQSI
SAAVHASLDALAYYRRHLGLAATSIQWAPWADGSSATSPQIVRHWLEKGGVSSVRNPLAA
VSAILKNHTAIGAVVACFHADPTIMHEMGETDQECTFLSSGPAANTRDSTSGNVKVRTNP
VKSRVFQNVSPSTDTCGENHKDELLVILTQLVRREVIEIASCYVFFEGNNLSTDESLVDL
GLDSLSAVELRHTLQQRFCVNIEPTFLQANATIDSISALLVTHVATSLTGALPVLPLSCP
GLASAVDDCALVSLALRLPGRCDSLDAFWASLQSDSGYCRPGASEACDQCFMHRAGSGEL
PAESQSIGTNLDARKGFCWLSNRDAFDSHFFGISFTEALATDPCHRLLLEATYEALCKLN
TEQQSGTSGTPIAVFATSSSTQMRASLPSYTKPASSQNTQDNNGCLAASFLSYHLNLTGL
AVPIDGSDSASLIALDLGREHLRGTDSVCQAVVVAAGSLLPICSHGWPSACTSPTIRRFR
GRDDHAFPDRETYAVPRGEGIVSVVLQRLSVARENGNSPMAILKGISLIRMGRGERPIPS
QWRTADVKLRRKTIVEALKMSRVEPRTVAVLETDGLTGSQAEDAYTVEAMADIFGPRHLA
ESCSPLVIGNASLHIGQAREASGLATLAKLVLMLERGYAPPIPCLRRLHPDVKRGILPSG
FVMFPCKKMDLLAFRQHPDHVYGPNEKRDQKEGRPLIGCVSSLGSDKTSGCFIVESSPRR
HGRTSDTRVSLERAVPLAGTKDACSHNYLHVRSTDGSESEIRGDDRAVWLFCDDLWGLQS
VGRGLYCSDPAFAALLEQAERVLGNRIPQPLSCLLYPSTTAEFQKAEDALAFPRIAAFVL
FSLQWALATCLRHQEGEPTAVMGLGVGEIAAAAVAGILSLEDAVELLELLSSETRTCDYR
NKPMPGGNVNSGGLFDRGNSGTGGCGVAQDCKSPWVLCGLNKTPTSESAALEFSVLESRR
GSSSRISSETPTSNTTPHNRDVFQERFSRKPRRATCPSPIIRHAWEKVAHGNPENDEEAE
LECPSSQSRRANCPSPAIQHACEETAHGNHANDGEADLLMDVFRFRPEPSEPLGQVTARI
ALRNAICLFISTVSGRLATDTLIRAAEYWDPLVPKTQRVHRAVETAVQVAKTAKLVCIGC
SAQDGVHLSVGLPSVHPISPSPLRIFCFTGSSPSPQLLAPCESASGSSPRVAVVEHHGAD
SNLGGGAPWWKHLLFRLPQLEGFPSGCSASTRLLADRLVADVPTPDNHMINNPQTAAVQG
AGETLGTLREGSSGEGEDGEKGYRSESVNTQHPVYKVYRRCSEPELHESELSLLCSDTVC
QPSLEKTVELFIGTGLEQQGKLSTVSSSWLVFSDIVAPSPISLYSTLAFQNEDGEQRFCT
LNVASQVATVYAEKVKTQVCSIIIECKRGFKPPREIARCHFVKNQTAVGKHEPAVSSLSR
IRWLPATKLPEGWLRTRRPHVWPCKIKVTKAACPLPTRRVDLQEIYWGKRHILCRFRMPR
NPPRDGVEKSTQLIAILARLVTVSVGVAATCVLHETETSGRYSHSHPGPQVEDDQKTHMD
ALWVCPYVPFSECWCVIRHRRNGSSIKEGKGRDWETCDVEIFSENGTAVAVVLGFGIQSH
ALSMRMMEGRGNDGDSSVSTTVCVA
>A0A7X6AV56|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces malaysiensis|TrEMBL
MHADHPERRGPGSSAAPPDGTAPDTGQAPHTGEAPDTGEAGLLDIAVVGMDCRFPGARDP
EEFWRLIRDGVEAVSRFGEAELRAAGVDEDILRHPDFVGAAGVVPDGDTFDADFFGYPPA
EAAALDPQQRIFLECAWRALEDAGHDPAAFPGDIGVFAGQTVSTHQPAPLEALLTSPMDV
FQQMSSNDKDFLPTRVCHKLGLTGPGINVQTACSTSLVAVHMAAQSLLNAECDMVLAGGV
SWTALRSRGYRHQPGGIMSPDGHCRPFDADAAGFVPADGAGVVVLRRLADALADGDRIYA
VLKGSAVNNDGADKVGYTAPGLTGQQRVVAQALANADVHPDTIGYVEAHGTATRLGDPVE
LSALTRAYRSRGATSTGRCAVGSVKANIGHTDVAAGIAGFLKTVLMLHHGHLPPSVNLSR
VSEELDVADGPFRFEREGEQWKPGEWPRRAAVSAFGIGGTNAHAVLEEAPARPRMPSKRP
WHLITLSARDETALRRSSEECAGFLEAEPEADLGDVCHTLARRHPMRHRLAAAVPDRPTA
LDRLRAGAVTPAVQYGDAGGERPDATVFLFPGGGAHYAGMGRGLYRDEPDFRRALDEGLA
LLPDTELRARIREALSIRGGQRDGGPDPFADPAVGLPALFLTEMALGELLLARGVRPTVF
LGHSLGEYAAACFAGVFDKADALSVVVRRGEILADIVGGAMLSVAASEEDVRRRLTPALS
LSVVNGPRMCVVSGPGEAIETARADFAADGIDCRPVPIATAAHSALVDPALPGFRAFLAG
IRLRPPARHLISNVNGRQAGAEVAEPGYWVDHLRGTVRFAEGLAGLTAERPVFVEVGPGT
TLSTVVRAHPRTARATVAHTLPHPDAPSEDSEVLLAALGRLWVSGVDIDPAALYDGETRA
RQPSLRYPFTRRGFTRPDHDRATPSVAAGNAAGNVPGSGRPGAALYAASWQRTPPPPASP
PGRALVLTDGSPLGAGVLRWLTERGTAPLVARAGDPGGAFRRDGQEYVLDPGDPEQCAQL
LDAAREEQGSGAPGDGTTPLRVLDLWSGRGETGTGNDGGRPEREPVPAGFLALAHALGRS
ATPVELTLVTRAAYGVTGAERPDPLAACLAGAAHVLPLELEHVRLRVADVDPGEWAESGE
SGLRALAGPLAAEEPAGRGADPVAAYRGGHRWTRRFLPLARGGETPALVPGGTYVITGGL
GGAGRHLATRLAERHSARLILVGRGAEECDALDGDPRIVVRRADVTDRVRMAEVFREART
RFGALDGVVHAAAAPAGGMLQFLTPGALAEGLSAKVAGTYALVDALEAAGERPGFLALFS
SLGSFSGSVGLAAYCAGNAFLDTFAVHASRTLGIPALSLDWDRWQGIGMAREVERRHREL
TKRDLAPGLDPGQAAELFTDALAHLPVHQLAISLRPPDELLAGPGTPAPEPPGRTSPDTA
DDGGTGDGLPADESAGDGCEDERERAVLRIWEETLGVSGIGVDDNFFALGGHSLTAMRIA
QRFNDRFGTTVTAQDLLRSPTVAGLAGLAGNGPEESHE
>A0A086LYN1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii RUB|TrEMBL
MAKPSPHSQPSIWSEKWAYHSSVPENDAVFKVPKKAWIIVGVPSQHMAEVLLSLKRMGLD
TSRVCGLGAISSMETLQNLVQGGTWAGMLVVSGLWATVSAVESLTETAHILRHYACLSTE
IEVPVLAVVTRGAQRSVVSPETFGQRERPTLESVPQQNQVFGHLEDEVPVHAGLLAFCRT
LRLEMGRCCRRFKPFLYFDTDRLHPRQSKESLDYHLGAVLKWLSRNDVPASFSEQIRPDS
DTLREWDIVIRKQSYFVPRVAPVLLKQPSTTAAGRIQKAKSYIVTGGLGGIGIVVASWLL
RQGAGRIFLWSRRGVPTDDVKETNQWCELNAAMETGRIQTVSCDVSEIEQVRHSIVLAVT
DSILGGIFHCAGTEGKGKLQDVSQQDIADVYASKVEGAWNLHRICSEMSINTNLDFFVLF
SSIAALPGNDAFATYAAANGCLDSLAEHRRSLSLPARSIQWGPWLDAGMAARTPSFERFM
RSRGIRGFHNEEAISHLETLLTADESLTCCAAVHVDWRIYAHIFGSHVPTWLQDVVPGLQ
TSLTPFSESNVPEQMHGSMDIQGVQSAVIDVARRLCGAEGIVSASTEISSLGLDSLGAVE
FRNALQEALKIKLPASLLVEYACLKDIIQFIMENCFSDAARSTSDLVPLVTREPAANDQG
FAVVGMGCRIPKNATTTEEFWDMLLHEIDAVCEIPMDRFNIDAFYDPDPEQDKCYTREAA
LLDHPDFFDNTFFNLSDQEVLAIDPQQRVLLEVAYEALFEAGFTKEALLGKDFGVFCAAY
NNDFQFTNLTQGKATMCVFDKGEGRGRIPSLGEAAGYPEPGGFMCFIPNRISYSFGLTGP
SIGIDAACASSLVAFDAAVTKLKRGACSGALVGGVNIILSPTFFLGGCKAHQFSRAGRCK
TFDCNADGLVRGEGCGAAFLLPLDAARETGAFVHAVVRGSATCHYGRSSQITSPNTRALT
RVLRLSLQDASTAPSLVRYYEAHGTATVLGDVIEMSAVKDVFQTGRNAAAPLHMGTVHNN
IGHLDAAAGIVAFLKTVLCLKHRFVPANIHFKSLHPDIHGIDTQLIKYTRESHSIMTDDV
ATGVRKTIFGANLAYGMGGSVAAIITESGDEEADRRSLKAAPRHVWNHRRFPLNTQKFVY
LMGAMGQISMDDMPTPQSDVIHVMKRLSATALNVAFMRKLSPSTCAAGSIRSVFLTGATG
FIGSQVLFHLLQVKRQDPKLGTEDKKLTIYCLVRARDRAHGIYRIRDSLVGRGIEWKHEF
DQQVIPVIGNLEEGENMGLGPKQMQYLEQTVDAVYHAADYVNFAAPYDALRKSNVLSLIP
ILKLCTTYVAKPLHLVSNFAHHLQYFAGFSEDLNIAVDETVSPPLSPASIDRLEQQMPAG
IIGYPWTKWAVEEIIGRMKDVLHERCEEEGQRVSMEESEKKDILSKLQVTVYRLPNSCVY
YNNGYTNFANASLSLVLASAQERMIPPGVLPVGAPFLTTPVDLITGILVKLSMTERKRHH
VYHLVSLRVARRKHVVQAIKWLFPDSVECTADELFRRIDENKENSPAHPLRAAMRFWRRY
WYSSDTDRDSPFPVAVNNVEDDLPGVMATFPSLADTWLRMASYCVKNYHMVRHPFTLAIS
FERLKKAIAGITKQRIDELALPSQTQELLNETCSTEDTTDIAAVKALVEHANLRKYDDCA
VSDVPDPRARA
>A0A2P9F4L7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MA5143a|TrEMBL
MTTEPNERNTVSELDGRIAVIGMAVRLPGAEDVTDFATLLRRDGVEVDEVPPSRWARELY
LGDGAHQGTHHRGAFLPDPFSFDHEAFGLTAEDAVLLDPQQRVMLEVGARALEDSGYLRT
RRRLDAGVFVGARMNAYGFDHGRGLGADGTRGPSDSPMAGPGDGPRPASLWGRSQNFMAA
WLSDRFDLAGPGLVVDTACSSSLTAVWLACQSLTAGACQLAVVGAVDLLIDPLTFVLLSR
TGALSPAGLCRTFDRRADGYVPGEGAVALVLKPMGAARADGDLILGAIAASAVNNDGRTM
GVTSPNLEAQVELLGKVYERIDPLSVRYVEAHGTGTAIGDPIEARALTEVFGRHGVPRNS
VALGSLKRRIGHLHSAAGLAGLAKVIVMLRDGIVPALTVEDPNPRLQLADSPFHLPATNG
AWPEVPVRRAAVSGFGFGGTNAHVVAEAVPPAHREEGHAAGPSRTTAARAIHQLLPLSAD
TPYALRELVAQWIEFLPTVTGDLDDVCATARLARPHRAARVAVTGADATELASALRAWLL
RPEAPDATVRPGRRGEPAVRVRPSSEEAPPGWLRVLDRSVPAVHEIMGLFETATGVPLAD
FSGELLRISEGIALTVALRDTGVPEPAVDLHTGWEALRDFAWGRVPLEEALADVLRRDGD
PAPGAEYGPAADDALCGRLARARDEREVAAELAAITAGLFAAGQDIDWAAYQRDTAWRTR
LLPSAQPRGRALDLREPLRSPEPGAPAELVRDEGPAGYVFARVFGPGEAPLAQHAVYRRI
MLPGVAWLEFLREGAALRGEPFHGVRDLLFHRPLIPSGASRVVCRVDGQGRFTVDDDHDG
GPFVTGRLLGEAVATPAPVPVASLLGSCGEVHAGSGLYRWLRRIGYHHGRYYRNISWVAA
LPDGGTLARVEGARQRELNEPGVELFPGLLDSVTIAAIAPDNPVFGASEASAFIPLSAAG
VHLHGPLHDAAYVRTETAFWNEEACRVTQTVTDAAGRPLLVLADLSSKRVPAEAFAATRP
PAHRPATPPAPAPAPGPAPAPAPAPAPAPAPAPAPAPAPARDTAPPADPVSTPPPPPTAP
VRRSATPERVLGWFLELTGTSVGDADTEFLSAGFDSVGLVSLSERISSEFGLSLYPTVFF
EYPTPRLFADFLVTESPDVAATLVPPTPASPSPDEAPTPASPPAAQPTEPPTTPAAVTPT
TLLGSPPTPSESPRPRDIAIVGAAVRLPTAHTLADFADLLREGRDTVGPLPEGRWSRPPH
GPVPYASFLEAVDEFDPGPFRISPREAPLIDPQARIVYETIWQALEDGGRAGERAADSRT
GLWIAYSHDHYHEERARHGVPDGRGLGLEAMIPNRLSYLMDWHGPSGLVNTLCSSSLVAL
HTALQHLRAGDIDTAVIGAVHAGLSPEYFRSMGDLMALSPRHRCRAFDSTADGFVPGEGA
VAVVLRRHDDARRDGDPVRGLVKGAAVNHGGRTTRYSAPSPRGQRDVIAEALRDAGVAPD
TIGLLEAHGTGTSLGDPIEIDGLTRAWREHTDRAQYCAIGSLKSNVGHLEPAAGLAGLVK
ALLAMEHEVIWPTLHVARPNDRIRFEDTPFYLADRPRPWPREGHPRRAAISAFGMGGVNA
HVVVEEPPRPTGDTPVPQDSHIVRVSAADETTLRDLAGTYADHLTGLAEHRLSEDHVTER
RHSEGRLSEDHLTGDPLGDFARTVNTARAAHPYRTAVHGRTAAELAARLTEVASGAAPTT
RHTRTATTTAFLFTGQGSQYARMGEGLRATEPHFQEALDECADLLRPWTDVPLLDLLYGD
ARHLLDQTRYAQIGIVGVQVALVTFLRAVGVRPDVVAGHSLGELTAAWAAGVLTLPDLLR
LTALRGELMQAQPATGTMAVVHTDADALTAELRAYPGIEIAAHNAPRVHTVSGPAEMMAR
FREQTSSRVQPLTVSHAFHSAVMEPALAPFADAVAATPLAPPVIPFASALTGTWHSDVTA
TDPGHWAQAIRRTVRFGQAVTTLAETGPHTVWEIGPHPQLIPLARATLAEARPDLTLLWI
PTLQRGREDQPQLHAALTSHHNHTGTDLHWTGLHHGKRQSVTTAPGYPFRRRRFWITPGA
PDAQGPAPTTITPSNHTHETKRPEHHG
>A0A011QU70|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Candidatus Accumulibacter sp. BA-92|TrEMBL
MTGRVAITGYSFRMPGTSTSQYWQDLLDCRDLVTQVDPGRWAQDSFLHPRRNHPGTSYTF
AAGSLGDIANFDAAFFGISPREAALMDPQQRLLLEMSWEAIENSGIKPSSLRGSRCGVYV
GIASADYSYRLADDLAVIDSMTATGNTASIAANRISYVFDLCGPSMAIDTACSSSMVAFH
QACRSILSGENAQALAGGISLHLHPYGFLVFAKATMLSPRGRCSVFDASGDGYVRSEGGG
LFFLKDYDQALADGDPILAVVAGSAVNTDGRKSGLTVPSPQVQAALLEQTYAQAGIDPRA
IDYLEAHGTGTAVGDPIETLAIGEALGKRRDADKPLPIGSVKSNLGHLETASGVAGLVKA
LHCIKHRVVPATIGVETPNPNIKLDDWNIEVVTRPLALKETGKLIVGINSFGFGGSNAHV
ILESHQQAEGEAPATSGAGLLPLIVSARDSAALQAAARDFADFLTDQPASALYDIAYTAA
FRRERHPQQAIVFGRDAKAIASAFRDFAEETNAAEKVSAGTAAATVDSGSGLATPAGLAF
VYTGNGSQWAGMGKRLLSEEPVFRDAIREVDALFRRHATYSLEDELAGVNGEENRYELTE
IAQPALFAMQVGITRMLAQRGLTPSVVTGHSVGEVAAAWASGALSLAEAVHVIYQRSRLQ
GTTKGLGQMCAVALGQEAALALLDELGLASLLTLAGVNSARGVTIAGKAEQLAVLEATLE
ERNIFHKRLDLDYAFHSAAMDGIEVELREVLADLAPRESELPFCSTVSGKQLAGRQLDAE
YWWQNIRQPVLFASAINTILDDGANIFIEIGPSPILRSYLNDCLKERAIEGRVIATGRPA
DDSPQGVWGAASQAIIAGANPDWQPFFPRPGRFVQLPSYPWQRERHWHPVTAASAGLIYR
RKLHPLLGYPLPQHALIWENELDTQLCPVLADHVVGEATVFPGSAFAEMALAAAAAWQPD
AVAAIENLEIRTPLLISDERSTNVRTTIHAHDGSLSIESREQLASEPWMLHATARLLHDT
EDALLREKGPALPGRQPDFDASSHAALTRAVGIAYGPAFQCIDHGWVQGNSVLAVYRIAA
SVDSQLASHHLHPALLDCAFQLIFQLLKNAVETHDGLAFVPVRMGRIALRSGMARPSFAR
ATLLRRSSRSLQAEFAIFAADGSTIAVVSDVRFRSVRLSRNAADQLRCLAYHAIPRPHPL
SPAARPSIAHDKVRAALLDLVRRAALKGTHRRYSEEVDPLLDSLCSRFTRRALQSLSPDG
QSLPAHAVHACQTATPEIAPYLTQLLSLAENDCSLASADSGWEIVPDVRDQSSAQDIWNS
LVTDDPDYFQIVHSVGLVGMHLGELLAGQRSLSGVCPQESSLATLLRQVLGTRGKQKIGG
ALRDLIDGGLRDLPAGQRLGIVEISEGSPSFIMDACMALDCNRADYCFASTSAATLSEVA
AQLKECSPGSETQLIADYPEAAGGKSASAASCALAILVLDFGSVELAIQAIDYARSRLLA
GGSLIVIGQHPARWIDFVFGAQATGWSQTESGRWLSSQRPSYFWQQQLQVAGFTSSEPFE
FSPDTLSGPYLLLGQLSESDASPSDTPRSTLRSWILFADQDGFSARLSDQLTRKLQARGD
LVIEARVGESAQIEALLRETTANYGELDGIVHLAGILPEADGAPAEAAAGSDSADTIFDR
QLARCTTAAGIFQACANTQTKTTCWLITANAANSLLPQRPGTAPTARVAADSALWGFGRT
MLNEADHCAIRLIDLQTPLAVETAAAALDREFEQPDGEQEVILTSNGERYALRLGIEERP
DGQVHEALEQPSLSLGFQLPGQLRNLRWEAHPRRELAPGEIEVEVHATGLNFRDVMYALG
LLSDEAIENGFAGPTLGFEFSGIVSRTGSTDSVFNAGDDVVGFGPSSFGNRVVTQATAIA
HLPPDISFEAAATIPSTFLTVYYALHHLAQLQPDEKVLIHGAAGGVGIAAVQVAKWLGAE
IYATAGSDEKRDFLRLLGVDHIFDSRALTFADQIMAQTGGQGVDVVLNSLAGEAINRNFQ
VLKPFGRFLELGKRDFYENTKVGLRPFRNNISYFGIDADQLMLVRPDLTRRLFAEIMALF
ADGVFHPLPYRAFEAEDVVDAFRYMQQARQIGKIVITYGHGIKHVHLPKASTRQHLELTA
EGSYLVSGGLQGFGLRTAEWLVSKGARQLILISRSGPQSAEARAAILRLEKQGVRVHAAA
CDVSDRVQLAALLAETTRTMPPLKGVVHAAAVIDDGLVRNLDGEQIRRVLAPKILGARHL
DELTRACTLDLFILFSSATTVFGNPGQASYVAANAFLEALAEHRRASGLCATCVGWGPIE
DVGFLARNEKIKEALQGRMGGNALNSATALDALEGMLLADRSGLAVLEVDWNALSRLLPS
ASSPKFQELAWHAEDRDGQEDQSEDIQRLLAELSDDELLVTFTDILSSEIGEILRISADK
IDPERSLYDMGLDSLMGVELMIALESRFGIRLPVMALSQSPTISKLAARVIQQLRASEEA
DEPDQQVLLLAQAEQVARQQGADVSQEVISGVAKDMQSAAAAAAATTTVRAID
>A0A378IAG4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Legionella beliardensis|TrEMBL
MRNIAEILQEREKKDGLKTIFKIIANDRKIIDITYSNLYKKSLSIAASLSRQKNGSQSSL
LLIPPGEEYIYAIFGCLLAGVIAVPAYPPTNNKKMDRLKYILNNAGSNNIITLKRLADNI
SSIVPNVNIIEDMIVTDPIDFIPKKVTPKDIAFLQYTSASTGNPKGVIITHQNLIANSNS
IQKSFKSTCKDVLGSWVPPYHDMGLIGCIIYPFIVNMTSILMMPTFFIKKPYQWLKAISD
FKITISPSPNFAYELWTRTVKEEQKKDLDLKHWRIALNGAEPINVATMERFAQSFAICGF
DRKALFPAYGLAEATLMVTGKIENEPLVSCQVDKKALRNNKIELTKNEASSICLISSGQF
NDGFDIKIINPKTLVSLKPYQIGEIICAGPSVTQGYWQNSKLNKQIFCSPKPNLENKSYL
RTGDLGFIDNKSNLYVTGRIKDIIIIHGRNYYPQDIELSIVNNYPALSINSNIAFAQNDA
GYDRLIIVQEVSKNIKKFSELFDEIINICIAEHDILPDRIVLIKRGSLPKTSSGKVQRSD
CRQQLAAGLLPIISEWKSVSSNNKISNNDTLQPSGFAQYDLNQNILNWIKSWLASYLNLN
IEQIDPNKNFAYYGLNSVIAMEFCTALQTSLNYELSPALLWQYSTVNLLANYLIDSQKKS
LIPQPLQIENLPLEPIAIVGIGCRFPGDVNSPEEYWNLLCNGSDGITEVPAERWAVDDYS
DGPNTTGKIASSRGGFIKHIKEFDAMLFNISPREAEVMDPQHRILLEVTWDALERANIEP
LSISNSNCAVLVGLGTNDFGYLLHNNAEHYRTNTYFNIGNSHSAASGRLAYFYNLHGPVM
SIDTACSSSLVAIYNACQNLQSKKCDLAIAGGVNCILDPFISIGLSNANMLAPDGKCKVF
DEKADGYVRSEGCGIVILKRLSDAKEAGDNIIAIVKSVEINHDGFSNGITAPNPKAQKEV
IEKALSTAKLTPNDITYIEAHGTGTKLGDPIEFNALTEIFGSKGRKEPLRIGSVKSNIGH
LEAAASIASFIKVALMLKNKKIPKNLHLNSINPLINLQAIPAEIPQYLTEWTVEQNNKRY
AGVCSFGFTGTNAHAILEENTESISNHTDEQKAALAPSPYLFILSGQSREALQAQIVNYI
GYLKDNSDINLAELCQNLLNYRTHFQYRLALTATDIIDLENKLMSGDYLTNLIPVNNKNK
IAFLFTGQGAQYTHMGKDLYFAQPAFKQAIDECSAILNEYLPISLLEILFEEKNKELLNQ
TQYTQPAIFTIDYALAKFWMSLGIMPSAVIGHSVGEYAAAVIAEIMSLRDALKLIALRGK
LMQSLPKGFMLALNGPYENSLKVIDAIRQANPDLILDIAAVNSLQQIVVSGEKKAIKKVE
KICNEKAIQTILLNVSHAFHSRLMLPILDEFQKCAENITYHSPKIAFISNLTGLNVVIKP
NANYWREHILKPVEFAKGIKTLIDNNFNFFIETGPQPILTNFGIACHPESGKVTWLSSLK
KNEGDWQSILNSLEKFYLSGVSLDWKKLNKHLMNTMKKINLPTYPFQRKLYWPEILTTVS
NSSQNKLQNAVYSLQWREQEIVTCCSTDKQTGVWLVFIPTDYKIEQFSIDFQQKFEKIIY
VKPGTSFHNINRKLFTIDPNNLEDFDKLLAENSIISGIFYLWGLDLKNNDAEYTSSEDIN
NYVKTTCDGLLNLVNTVSKQPTHELSLWVVTYATLYPSQKSKLPIASPLIGLSKVINLEF
PQLNYNYIDIVNTEIKINEVVALLYKEVTAKTQGQLIAYNNNKRYTPVVSPYTLPTQLPS
SLFKSDYTYLITGGLGGLGFELCKWIVRQGGKYIAIIGRRKLNDQLENQLQELKGSAVVN
YYQADVSNLENLKQKMLQLIQEMPSIKGIFHTAGVLQDCLITNHTWQKFKEVADPKIAGS
WNLHQLSQKLNFALDYFVLFSSISSLLGSRGQANYAAANAFLDGLSHYRHSLSLPALSIN
FGPWENIGMTLNHEQPWLKVGVKNIPLGNGLQIIGKMLNTSSPQLILLPHVFEQKAVKFL
STMQLDLMHQLFGSELNSNYLVSEPVPDLFIEDSLLSKIQKQVDIEEKNKIIVEFLIKEV
SKILNINKKDYKLGESRLLELGMDSITGVELLNAINNAMPLSTLSIKALLFEERTIEEIA
AYIIELAALQT
>G4I5E7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium rhodesiae JS60|TrEMBL
MTDNTHQPIATPIAVVAMSAIYPGESGLTGFWRTITAGRDAISEVPPSHWLIEDYFDADP
KAPDKTYCKRGGFIDPVNFDPVQFGLPPNALPSTDTGQILALIAARQLLDQVQGEGREVD
LDRVDVVLGVASTTELVVQMGSRMQRPIWRKAMLENGLAEDEADEICQDIADHYVPWQES
TFPGLLGNVIAGRVANRLNLGGANFVTDAACASSLSALQSALHRLYLHESDVVLTGGVDA
LNDVMMFMCFSKTPAFSATGDCRPFSAGADGTIIGEGVGMVALKRLADAERDGDQIHAVI
RGLGSSSDGRASSVYAPRSEGQAKALRRAYERAGYDPSTVELVEAHGTATKAGDVAEFAG
LKSVFTDSSARIAIGSVKSQIGHTKAAAGAAGLIKAVLALQHSTLPGTLKVDRPNPAMGI
EDSPFYVNSQTRPWVRKSDQPRRASVSSFGFGGSNFHVTLEEYQGEHRAKRLRALPSELV
VLSAQSEADLQKRAADIVTAARSGESLARIAFEAAEEFDASQPARAGLVATDAESLAAVA
DRLRSALADGKAAELKDANIAVGFGPAREGKTAFLFPGQGSQYVGMGGDLALSFPEALAV
WDGLEGDLTDLPGVVFPEPVFDPAAVDAQKKELTAMANAQPAIAATSLAQLALLDVLGVS
ATAAAGHSFGEVTALAAAGVLPTESLVETARTRGTLMNEAGQGKDGAMLAVTATADDVRA
LLATQPESGSLVIANDNAPTQVVLAGYETDIEWAQTAAKAKGWTAVRLPVASAFHSEIVA
ASSAPLTAYLKTLKIGQPNFPVYANATAQVYSEDVAVQLGDQVRQVVRFREMIEAMARDG
VTRFIEVGPSRVLTGLVGKILGDSAHFAVALDDPKADGLRGWHRGLAALAADGVALDLVA
LFDHYAEPVKFVPAPKHVVKVGGANLGKPYPPADGKASITAKRTRTSVHSAPPAVAQAPA
PAPAVQRMEAPTVHPPVAQAPIVQQQAPVAARQVEIQAEVIEAPLSGDVWSIIDSIQKET
AEQHQRYMDVVTQSHQAFLDMSTQMMAQIVGEPATVAHTQRALTSVVPQSITAPVAAAPV
IAPPVAAAPVAPAPVAAPAPAAVAAAAVVAPAPAPVVAPVPAAPSVAAGDVVLAIVSEKT
GYPVDMLGLGMEMEAELGIDSIKQVEILAALQAKFPGAPEIPASELSGLRTLQDVVDTIA
DFAGPVSAPAAPAAVAVPAASAAPAGDVVLAIVSEKTGYPVDMLGLGMEMEAELGIDSIK
QVEILAALQAKFPGAPEIPASELSGLRTLQDVVDTIADFAGPVSASAAPAPVAAPAASAG
PALPAGDVVLSIVSEKTGYPVDMLGLGMEMEAELGIDSIKQVEILAALQAKFPGAPEIPA
SELANLRTLQDVVDTVSGFAAGGTTDQAAAVQHAAPVSSATVGLSCTEAELRAAPPSGLA
MAGLRDGIFITRENPDFADALVGALNARGLQAQAVDEAPAEAAAVISLAALAPARTPDDC
VAMHVRAFHAARSVAKSTAPTRLFVTVQSTGARFVAADVPVGVASLVKTAGWEWPNASVR
AVDMETLDAQRLAAELLEGGSGIEVALRADGTRLVAVDDIESSVGEGETISVASGGVVIV
TGGARGVTAESALALAKLHGLRLALLGRTPLREVSADEPSGTTAAEIATALAASARARGE
QLSLPQARAQAESLLAEREVRATLSTAEKQGTPARYFAASITDEAALRGVLDEVRQNFGP
IVGVVHGAGVLADKRLEDLDDDGFVKVFTTKLVGAEALLDATSTDELRFISLFSSIAARA
GNPGQSAYASANAALEAIAARESARRNGECVVRAFGWGPWDGGMVDATLKSRFLAGGVGV
IPIGEGAQFFAEHALCRSSATAVVVAAPAEPRLRATRLDWEVSAEDLPVLTDHQVRGKVV
VPVVIALDAMLRAARGLVADACPVVRDFQVLSGVTFAEGERPSLTIDFEPADSSSYTVSI
VDGDGRARYRATVDTAAVAEPELSVPQVSGSPWPLSVGDAYAGPLFHGPQFEVISQLDTF
GSAGGSATLKSLDELGWPQDGWAIDAASIDGGLQLGIVWAGAQGRPLVLPIRIARVVQHR
AFGDGSIGRCRLAAHPVNDKRVDFDIAYETTDGALIATLEGVEFYAAGSAADTSA
>G8SM54|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)|TrEMBL
MTSETESADRGPLRRAMATIRTLQSRLAAQDENRPVAIVGAGLRLPGGITSLAGYWDALA
AGRDLVAPMPAARQARFAADWATLPRRGAFLDDVLGFDAAFFGLSPREARHLDPQHRLLM
EVAWEALEDAALPADRLGSRSAGLFLGIMWQDYRDWQAGEPDAFWTTGNGHNFAAGRIAY
TLGLTGPTLAVDTACSSSLVALHLAVQALRRGECEVALAGGVNLILSPRSTRLVVETRSL
APDGRCKSFDAAANGFTRGEGCGVVVLKSLDAARRDGDRIHAVIHGSAVNQDGRSGGFTV
PNVLSQVRLIEDALADARLTAADIGFVETHGTGTALGDPIEVEALAAALGRRNGGAPLPV
GAGKTNLGHLESAAGVAGLLKAVLSLRHRQVPPVVHFRTLNPRIDLDGTGIVVPARLTEW
APGAGRYAGVSSFGMSGTNAHVVLGAAEPSGPPPDDAPAPAGFEISARTEPALRELAARY
AARLATLPAADFPALASTTATGRSRLAERAWIAAAEPAAAAAALRELAEGWATPQVVRLG
PTDPAPEPPPVVRRVVDLPNYPWQRKRYEPEQREQPVEPAPLFTLDWRPAAPAGPSTRRD
PLVVAGDDTRLLELIVREAAAADLTGTVLGPLAGPVPPGWDIGDLPADRDGWSAFWSART
GRATVLLVPAATPLAQATSTGAARCAAIVAAVGAAADRRGGRTHLVTRATRQTGDDDRPE
ATDHGLLHGLAPTLGLEYPDGWGGVVDLPADPRPTDVRPMLDLITADDPPELTAVRAGVV
LAARLTPARPGAGLPELHPDATYLVTGGLGAVGRHLTAELVARGARHLLIIGRRPRAALP
DPATGFLAELAAQGVDVHYRGDGCDTAVDLAAACAPLAGLPPVRGILHLAGTVTSAAPAD
LDPAAFAAAAAAKAGGAWLLHRAAVDWPLDFFVLVSSVSALWGSKGHAAYAAANGALDLL
AAYRRGQGLPATSVAYGPWALDGEGMADRATRERAERTGIGAMGAAEARSALAVAVPGAA
GHVIACRADLVRLGRVLPRLRAGLLAGHAEPVTGTAAGPVSGTTAGPVAPPAPVDAATVR
DTVAHLLAVQLGYDGAADIRPDMGFADLGLDSINAVDLAERLTARLGRAVPVTALFDHPS
VAELTAYLTGAGRPAAPAPPARPWSAETPAAPAPPARPWSAETPAAPAPPARPWSAETSA
APAPPARPRPAETPAAADPTRVRPSPGGEPIAIVGMACRFPQADSAGELWELLDAGIDAV
GPAPADRWGSGILRGGRVTTDQGGYLRGIDLFDAGFFDVPAREARSMDPQQRLLMETAWH
ALEDAGIAPSALRGTATGVFVGISYADYARLLARGGADDVDAYYGTGTALNATAGRLAYA
LGLHGPALAVDTACSSSLVAAHLAVRALRAGEADAALVGGVNILLDPMSSVAVSQAHMLA
PDGRCRTFDADADGFVRAEGCGVLVLKRLADARRDGDDVLAVIRGSAVNSDGASSGLTVP
NGSAQERLLTAALADAGLPGHAVSYLEAHGTGTRLGDPIEVAAAWRALGPGRDTGEPLLV
GSVKSNIGHCESAAGLAGIVKVLLALRHGRIPANLHFRTPNPHVDWAGTNVRVVAAGTPW
PRGPVPRVAGVSGFGFTGTNAHLVLADPDQPSVTPPTRPGSAHLVTVSAPDPDGLARVTA
AWHDRLTGAADGDLAALAAVSGRGRTHFRYRRSAVGRTGADLARELTAAGPVYGAAQPPR
VAFLFTGQGSQYFGMGRDLYETEPAFREVFDRCDDLMRPRLGTSLTELVFTGEDAAALHQ
TRVTQPALVALALSLVATWRSWGVEPATVLGHSVGEIAAAVCAGILDLPAACEFVVRRAE
LMQSTGPGRMLSVPAPEKLVEEWIRDTGLDLAAVNGPEATVVAGPADAIEALAARLSAEN
VRHRPLATSHAFHSRLMDPILDRLRGELAGLRTAPETIPLVANLTGQTGTTLDAEYWCEQ
VRRPVRFHDGLVRLGEIGADVLLEIGPDRTLTNLAGAAGLVPAGGAVSSLRRGIPARTAM
LTAAAALYRAGQRLDFDRVHPTRPGRVDTPRYPFARTSYWVRPQPVAATTPDASAGPAWG
TELRSPALPGRVFASHRSTTYPAHLTDHRLFGTVSVPGASQLATVLSALSGGRDTVRLQD
VHFPRALVLHEGERYEQQVIESAGPDGRRVTVQSLVHEETGRWQEHLVARLPAEPPATGA
DDGPRADHLRHRADRELTGERFYRHLHLLGYHLGPSFRWIDHIWIAGDQALVRLTRPVET
REDPGGYAVHPGLLDSCLQSAVCFAVDGEPDGEPDSEPDSGGAGLAIPFSVSRLAWHERP
AADAELWAHVRVRRDADGAGLLRVGSADIRLTGPDGRTSVLIEDFRFRYAPRALVEASLS
ARAEVRRVDWTPVVDDGERPGSVTVLGSPPIETALREAGLRLTGLDADVLVDARFTADRP
APAQIAAEVTRILRTLPADRGYAFVGPPGPDGRPVVEAISGLLAGLRAEQPDRRVRVVEP
REGWRPEHLAAALTAAIPEDGVLLAAGPDGLRARHLTGLRPPASPPVWDTAGSALITGGL
GALGLSVASFLVARGVRHLTLMARSGPDEPARQVLADLATAGATVQVLTGDVTDPADCRT
AVEQAGRDAPVRFVLHLAGTTDDRAFDGLTPDSFDSVFAAKVTGAVQLAAAVGTRPLTAF
VLFSSASAVLGSAGQANYAAANGYLDGLATVLRGAGVPATSVGWGPWSTRYRDGLADTPA
VRRAMSVRGLRALTDEQAWPVLDAVLAGGPDRLVVVAGGAEPAVPPSPAPPAAATDRGWL
RDRLGDPAGLRAAIGRMVGEVLGDPGPVDPGLGFMDLGLDSIMTVDLQRRLSHALGRDLP
VTVALDHPTVDRLAAHIEPAVAGEATEPADDLNRLDRDDLDPLDRDDLDPLDRDDLGEMS
LDDLVRAVRADVATEG
>V4ZF64|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii (strain ATCC 50861 / VEG)|TrEMBL
MEQKQEDSASTSKSEVNKSLVESLSTAKGARHTDDGFIFTNGQQNLHEAKKDQHGTSDST
LAEPVSNAILDPITRVTDALLVTADGTSVHKDEEELSLVAECFACVTGVEKSCLRPDTPF
LSLGLDSLTAVELANEIQRRMKQPVEPFELFEFADLRSLALYLRNKKLDHGKDARGRQTK
SSPERSLGIVQVQRPSVFVTGVACALPGSCQTPDKLWEILDAGIDCVGPIPPNRNFCASQ
NFAVIGEPRTANASFCVTEGGFLDDVDLFDNSFFGIPDAEAMTMDPQQRLLLMKAVEALH
AAGMATIDSRSAPIATFVGCCSTDWQRMNLGEQIQSFSATSHSASMLSNRLSYTLGLTGA
SITVDTACSSSLTALHCAMQELQHRHVPCHTAVVATVNLLLTTDVTLAFARAGFLSPTYR
CKTFDDAADGFVRSEGVVVFVLQTDVSETPTPNFKNQQEDNEGGQGECGTRIPASGYLCR
ILASTVVHGGKTGSVTAPSGSSQELLYKQTFACAQVPPRAVDLVETHGTGTRLGDPIEIS
ALCNSFAPDMETRKHRLVLGALKTNLGHLEGASGLAGLLKSVLCLNRQRVPPNLHLRKLN
RFIDFRSLPVLLPTKTVPLPASSSETKDAVALVTSLGFGGTYAQVAVQVPSTTGNEMLLR
NQETVQWNKKCFDVGKLVSQSNSFQSAVSHNDTKGPCFWEVGWEFLLEFDSITLTLPTLP
EQAPPAKWLVLTSPKAQQSFRKFSVNIFLPGIRMTFACLEELKAPEHLEAILKAETWTAI
VSTYTTETGSCMTDSSDLIGRTLQILQTYGQMASQSAVLPRLLFLTQGCFQVGAAASLLR
ASPYNAGIIGFVRACRLEIESLSGRKAPIYLIDFAANGTLTETLSAVSKLLGMIDIRNVD
ETEFAICGKRVFAPRLLPLHLGLEEILPAYDHYMDLTKKADESPAGTAKFPRLVEPANKA
CRVRLLALCLDEIFPIEAISPASKAFELGESRPCTLPYGYRNRRQKPSCTKWNERSYSHR
RIRYELPLCWLNRNKANVYFNQKRLGQSTCIFIEVILKLAVRFILPACFTKKMNAAPPST
ARENRPLYSALSDLKGLAFLCCAPGPDNASSLCGCSGILLEHGADSQHLTVGNVVCGIMP
RPHCEIADIPGILLHPSPPSFSCELAASLPPQLALLLWALNQAPPLVTPPAKRVSRVLIV
GAGCGVGLVAATHFQTLGLKTFAVVCTEEQVEALVHYQFPHAAIWCYDRPDLRSALRREL
GYSSIDMVVWALKQEIDSSNNHLLNLLKHGGSFVDLVACHPESRLGWRLDVKYVHCTLDL
AARPYHAKEFSKNLALSCEILRQKTASQRQQIMHVFFDHAHRLGQHCSLASVQMTEAATP
QNVTSPADLSKQNVSFRPGVNAVEFVSGYSHAGSVVCSLPSPIFFNKASSSNGNCESNAS
TASSSAALGTEASSNVRTGTVLIFDCGSGNTWQHLRQWLSDEGASHIVVVHACAEEGADR
LGVKTLHPSRVNGGQGCSQTLIKEVKCRPHHPEEVVELFKLLKEGLHFPLVRGIFYILGE
KLDSLLANQTTSSVHDMMKTASGAWSIHHALGQLGMEADLDFFIFFSSISALFGSISQSI
SAAVHASLDALAYYRRHLGLAATSIQWAPWADGSSATSPQIVRHWLEKGGVSSVRNPLAA
VSAILKNHTAIGAVVACFHADPTIMHEMGETDQECTFLSSGPAANTRDSTSGNVKVRTNP
VKSRVFQNVSPSTDTCGENHKDELLVILTQLVRREVIEIASCYVFFEGNNLSTDESLVDL
GLDSLSAVELRHTLQQRFCVNIEPTFLQANATIDSISALLVTHVATSLTGALPVLPLSCP
GLASAVDDCALVSLALRLPGRCDSLDAFWASLQSDSGYCRPGASEACDQCFMHRAGSGEL
PAESQSIGTNLDARKGFCWLSNRDAFDSHFFGISFTEALATDPCHRLLLEATYEALCKLN
TEQQSGTSGTPIAVFATSSSTQMRASLPSYTKPASSQNTQDNNGCLAASFLSYHLNLTGL
AVPIDGSDSASLIALDLGREHLRGTDSVCQAVVVAAGSLLPICSHGWPSACTSPTIRRFR
GRDDHAFPDRETYAVPRGEGIVSVVLQRLSVARENGNSPMAILKGISLIRMGRGERPIPS
QWRTADVKLRRKTIVEALKMSRVEPRTVAVLETDGLTGSQAEDAYTVEAMADIFGPRHLA
ESCSPLVIGNASLHIGQAREASGLATLAKLVLMLERGYAPPIPRLRRLHPDVKRGILPSG
FVMFPCKKMDLLAFRQHPDHVYGPNEKRDQKEGRPLIGCVSSLGSDKTSGCFIVESSPRL
HGRTSDTRVSLERAVPLAGTKDACSHNYLHVRSTDGSESEIRGDDRAVWLFCDDLWGLQS
VGRGLYCSDPAFAALLEQAERVLGNRIPQPLSCLLYPSTTAEFQKAEDALAFPRIAAFVL
FSLQWALATCLRHQEGEPTAVMGLGVGEIAAAAVAGILSLEDAVELLELLSSETRTCDYR
NKPMPGGNVNSGGLFDRGNSGTGGCGVAQDCKSPWVLCGLNKTPTSESAALEFSVLESRR
GSSSRISSETPTSNTTPHNRDVFQERFSRKPRRATCPSPIIRHAWEKVAHGNPENDEEAE
LECPSSQSRRANCPSPAIQHACEETAHGNHANDGEADLLMDVFRFRPEPSEPLGQVTARI
ALRNATCLFISTVSGRLATDTLIRAAEYWDPLVPKTQRVHRAVETAVQVAKTAKLVCIGC
SAQDGVHLSVGLPSVHPISPSPLRIFCFTGSSPSPQLLAPCESASGSSPRVAVVEHHGAD
SNLGGGAPWWKHLLFRLPQLEGFPSGCSASTRLLADRLVADVPTPDNHMINNPQTAAVQG
AGETLGTLREGSSGEGEDGEKGYRSESVNTQHPVYKVYRRCSEPELHESELSLLCSDTVC
QPSLEKTVELFIGTGLEQQGKLSTVSSSWLVFSDIVAPSPISLYSTLAFQNEDGEQRFCT
LNVASQVATVYAEKVKTQVCSIIIECKRGFKPPREIARCHFVKNQTAVGKHEPAVSSLSR
IRWLPATKLPEGWLRTRRPHVWPCKIKVTKAACPLPTRRVDLQEIYWGKRHILCRFRMPR
NPPRDGVEKSTQLIAILARLVTVSVGVAATCVLHETETSGRYSHSHPGPQVEDDQKTHMD
ALWVCPYVPFSECWCVIRHRRNGSSIKEGKGRDWETCDVEIFSENGTAVAVVLGFGIQSH
ALSMRMMEGRGNDGDSSVSTTVCVA
>A0A449H5M1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia farcinica|TrEMBL
MGCRLPGIGHLDDLRRPPGTDVPVAGVDVFDSEWFGLTAPQAAVLDPRLRLALEVVVEAV
DDAGIGYRLRGSDAAVVVAVRPGRDQPESGRADFAPAQGISRLFELYGPSSPVVTDRAVE
SGIRLLVDRAVPWVIVVGVDVEPDDAVDGAVAQRDPVAAGESRRAGCAVLVLQRVADARR
AGSRVHAVLEIDDGRSVGEAAVGSDPLPAARSVMRVLRAIVSMESETRALDHGATATSTG
AAQPLLPNEIRSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGS
GSGSGSEEGTGWGGKGTRVPGSRITVHRNAAQALPRSIDPPVVIAVTGRDRRELGTTALR
LAHHLRYAAPHDLARGDRLALHELACATTRQLPLALRAAVLAADLGEADAHLRALAAGAT
GPGIVAPRPRHRGGLLFVFAGPSEPAPRLGRAPAARFPAYAAAVAAIADAIRSAGGPRIW
TARFGFRVAPDSGWAGPAFAHLATFAHQVAVARLLEAWDVRPSGVCGYGAGEIAAAAVSG
ALTTADAARVAVEYSRTLAHRVPRHIDAEPTPPQWENLDRSGTAQTRPWSSALLLASIDE
AARLVAPLRHTVTIAAARGPQSVVISGYPPDVDTVVRRAMRRGLRARALGRDHPADPVAG
AELAGHLAGLTPRTPRIPFYSTVRRGGLLAGAATDAAYWGANLGDAVHFDAALVRAIDAG
ASSVLTIGPSTELAAAVEGFEQFASSTYTTGGDDEAAALLHALAALHAEGRRVDWARQGP
FTVPPPRRRWRHTAVGSPLPAVIAGAEPDFDHPGVIDHLYGGRPAVPVGYWVSALLHLAR
RHAASEMLTDLALGRLVAPDDLRQARFRDDGPGGFRVTVPDGTGPDGTVAVARPVPGPTP
ADIVDWMRLVDDGRTARRRLRPLGPGAYYTSLRRHRVEYGPRFPIPERIETGGGRTFGVL
STDGEASIAVEQCLHLVVAAARDMLTGKLVPEVSAIGTVWLAPDGGAAVEAHATVRERAP
HALTGDVVGTDRDGVPLLALRDVRIRFREGDDAATVRPAESAPFRTQVWLPVTPAPGAGH
GEPARLLVVGDSATAARLARATDRTIRTDLCATPEPAAPDHHAGYTGAVLVWPHGTDATA
AAAAHHALDVLRGLRERCRGQLTLVLPRPALRGGADAESAWAAAALARTLRAETGTPVRV
VWADDDPPTLARLADLLTGRHTLDDPELRIGADGVTARRLRPVPADPLPAPRIDPGGTYV
VTGGLGRLGAVAVRWLLDAGARDVVVLTRAPRPVPAPLDGLEDRFVVVRCDVTDRAELAA
ALGDIREDGATIRGLVHAAEVFETAAFAEVTAGQLTRLFEPKVTAARHLLALTAHDPTDF
VLLFTSAAGSLGAPGRAAYAAASAAADALAGGRRRVLALGWEIRRQPGGEPADLDGAAVR
RGAELLGAALRHRVPHLLIGSGEIE
>K9UXZ1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Calothrix sp. PCC 6303|TrEMBL
MGKLARGKQLAMPLAARLEYPVWEKVLRTSGLSEEDTQKIIAKFKTAYVKWDENAFPGML
ANVVAGRIANRLNFGGTNCVVDAACASSIAALKMAISELLEHRADIMLTGGVDTDNSIMA
YISFSKTPAVTPGDNVKPFDAKSDGMMLGEGIGMIVLKRLADAERDGDKIYAVIKGIGTS
SDGRYKSIYAPRQEGQVKALQRAYEDAGFSPATIGLVEAHGTGTMAGDPTEFASLREYFS
VDNPRKQYIALGSVKSQIGHTKAAAGAASLIKTALALHHKVLPPTINVTEPNPKLNIKNS
AFYINTETRPWIRAEGEAPRRAAVSSFGFGGTNYHVVLEEYTQETGKNSYRINNAPFEVL
LSALNPGLLLTRCQEVLANLQSGNSEKQYVELVEESKTKNIPLNNARVGFIAESPQEAIK
FLKMTVDLLHKQPNSPAWEHPQGIFYRESGLELGGKVVSLFSGQGSQYLEMGRELVMNFP
ALRNLYGYMDSLLLKDNMQPLSEIVFPHPVFEDAEKNAQIAALQRTEYAQPAIGMLSAGM
YKILQQAGFKTDFVAGHSFGEITALWAAGVFNDEDYCKLVKARGQAMAPPQDPDYDAGAM
LAVKEDLHKVEAVLRHFPRVMIANYNSQKQVVLAGPTAEINRVKQALQDQSYSAVSLPVS
AAFHTPLIAFAQKSFAIALKSVQFQTPKLPVYSNTTGNQYANEPQTIQHILESHLSSSVL
FKQEIEHIYAAGGSCFVEFGPRKILSNLVKEILGERPHLTIALNSNSQKNSDRTLREAVV
QLRVAGMNLQNLDPFQQPLTVPPVTAGNKTLTIKLNGANFISEKTRKGWEETLNSTDKVQ
LMGTSDTVVTSTQEIQPVISAKELETVINSPVSSNGHHLPTVSNGKQPKFSIPQPDSTVS
KVICSEVSQNEDFSGNSVVNPQYSELPQLTSSTNQPVRESKMQTIPNNPGDYQQILGSLE
YVLTQFQQNQTENLQVHGLYLNNQKEYAQTFFQLMQQQNGLFAKNGNSDIKPVVMESLER
SMMQFHSQQGETLRIHEQYLQNQIEYTQSFLKLIQQEYKQLIAGEVTVSSTILTESKSTP
VFASVPTPTQVTPVVEGVPTPTQIQPVVESVAAPTQIKPVVESVPTPTQIQPVVETTPAP
TQVTPVVESIPAPTQIQPVVESIPAPTQIQPVVESVPTPTQIQSVAANIPTVTIDLSDLG
DKLLAITSEKTGYPVEMLEMDMDMEADLGIDSIKRVEILGGLQEIYPNLPEPNLEDLAEL
RTIGQIVEYLQTNNAPAKPVAPVEMMISAVQKATDIPIPELEITPTIPVITPDNTPTPVV
STTPTVSSTVSSDFANLDKSLLEITSEKTGYPVEMLELDMDMEADLGIDSIKRVEILGAL
QEAYPDLPKPDNMEELAELRTIGQIVTYLQNLAGGEKKKPESDSLEVESREQGEMRQGEQ
GSRGAGGDEELLQVSSLPITEFGEIHTPVNCNIKRLPARLLELGKPDFLDFTLPEGYVAI
VTDDGTLTTTSVVQSLCDRGWKVVVLNFPASLVPEKSPLPQGVNRVALNDLSEEHLQQQL
SAIADYFGTVAAFIHLHPHFPNNSPGILYHPDEKAIVKHVFFIAKYLKKPLVEAANHTRS
CFLTVAHLDGSFGLKHQNNFGAIGAGLFGLSKTMLWEWANVYCRAVDLSPELTSNEAANS
IIAEIHDANRYLIEVGYSKQGRVTLIAD
>A0A083ZWE1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Serratia sp. DD3|TrEMBL
MIDNVALSGWGVTSAYAPDFPALINGLVEGRLIGSQPWFATESEWQDLRLSCNPHYVPEA
QPFGSAFSRLQPVIDQALAKAGLGQEHLQGKRVRVYLVGHGQRADIADYLGYQDRNDQEE
LLFFPKIKRLHASNFDQDRLVKQLTQTYQLSWPAVSLYCASNSALAAVHLAQSSIAAGEV
DLVLVIGWLETQTQDIIFLGGQDMLGEGSSQPFSNHNSSILPTNGVVALILESGQHAQQR
GFKPSAILRSSMFCQSSGGRGSSSFTADFRTIAQTLERVLVDADLSPQDIACVFPHANGV
IASDKAEAMALQKLWGKAGIPVVSYKGQIGYMVSCCGLLDLMLIADALQQRRLLALTSRY
PIDETLQIHVHADSPPLALEKEHIIKSGIGLDGSAIAMVISANWEGANE
>A0A2N9BJJ4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces chartreusis NRRL 3882|TrEMBL
MNAANNELVEALRASLKETERLQRENDRMVERAREPIAIVGMACRYPGGVASPEDLWRLV
ADGVDATSEFPADRGWPEDLYDPDPDASGKSYVRRGGFLDDVAGFDAEFFGISRREALAM
DPQQRLLLEVSWEALERAGLKAEDLRGSRTGVFVGVSNSGYIPEPGRVPDNVEGYSLTGN
IASVLSGRVSYTFGFEGPSVSVDTACSSSLVALHLAVQALRQGECSLALASGVMVLANPA
AFVEFSRQRGLAEDGRCKPFAASADGFSAGEGVGVLAVERLSDARRNGHRILGVVRGSAV
NQDGASNGLTAPNGPSQQRVIKAALENAGLQPQDVDAVEAHGTGTKLGDPIEAQALIATY
GKDRPEGRPLWLGSVKSNIGHAQAAAGVAGVIKTVMALRNDMLPPSLYADEPTPMIDWKD
GDVSLLSEGVAWPRGERVRRAGVSSFGVSGTNAHVIVEEAPAAEESAVEPVVDGGSRLVP
WVVSGAGPGGLRGQVERLVSFVGERPDVGLESVAVALAGRDGLRHRLAVVGESTDELSNR
LREFLADELPAGAARGVADARPKVAFVFPGQGWQWVGMGVELLGCSDVFAEAVGECSAVV
EELAGWSVVDVLQGAAGAPGFDRVDVVQPVMFTVMVALARLWESVGVVPSAVVGHSQGEI
AAAHVAGVLCLEDALRVVVARSQALVEICGQGAMASVALGRAEVEERIAQLESVSVAAVN
GPASTVVSGGAEEVAGLVAGLVAGGVRARRIDVDYASHSVHVEQVRKRIEAALAGVAPRA
GRVPVYSTLTGEVLAGPEMDGGYWYANLRGRVEFEQAVRRLAQDGFTALVECSAHPVLVP
GVEQTLETVPGAQVAVSGTLRRDDGGLRRFLTSAGSLWTTGVDITWPVLLPETQPVELPT
YAFDRSRFWLERTESTGDVSGVGLGVVEHGLISAVVEVAAGGAVVLCGRLSRSRQRWLDD
HAVSGQVLFPGTGFMDLVLRAADEVGCQVIEELVVQAPLVLPDTGQADLQIVIEPAGDDG
RRQVVVYSRPAGTDAVWAQHAQAVIAQDSTPEVPPVGVWPPVGAGVIDVSGLYGELAERG
YGYGPVFQGVRAAWRLGDTVYGEIALPESVVQEAARFGLHPALCDAAAHLLQFSKVLDQD
GVWLPFAWNGVRLLATGATRARVRITPLGEGSVRMDLYDVAGEPLAVVEQLTARRLDPAE
LQPSSTSTAAARGLFALSWPALPTPDTPQPADTIVWRPQDSGEADTWGLPAVTDLEDVPA
SVQVVVLPVSGRDRDVTEVSTAVLAALQAWLAEDRLARARLAVVTRGAVAVDTGVGPDAG
ADVVDLAASGVWGMVRTAQSEHPDRFTLLDLDPHQHADTNALLGALSVSGEPQLAWRDGQ
LHAPRLVRALTGGGVLHGVSGFGAGDTWRVTTQGTGSLDALAKTPHEAATRPLKPGEVRI
EVRAAGLNFYDVAVALGMVDSADGLGAEGAGVVTETGPGVSRFAVGDRVLGAFPAAFAVR
TIADERMLAPIPAGWSFEQAASVPAVFLTAYYALHDLAQIQPGQRVLIHAAAGGVGMAAT
QLARHFGADVYTTASPAKWHTLTALGIPEERIASSRTTDFAEQYLNHTGGSGMDIVLGSL
SGEFVDASLRLLTPRGGRYIEMGKTDIRTPQQITATHPGITYRAFDLKEAGPTRTGEMLH
HLLTLFTHQALTPLPRTEWDLARLPQALRHMSQARHTGKNVIRIPRPVNPHGTVLITGGT
GTLGGLIARHLAHHHHMRHFLLLSRQGPNAPTAPALHHDLTQTGAQATITACDLTDPHAL
AKTLADIPTEHPLTAVIHATGHLDDATLTHLTPHQLTTVLTSKATTAHHLHHHTLPHDPA
VFLLFSSAGSILGSPGQANYSTANTYLDALAHHRRHHNQPATSLAWGLWQQTSGMTSHLD
DQDKARMARNAIAPMSTPEALELFDAAALPPHALLLTALLDQRQLPRLPLWQRLAATTRA
VAATVEEGPSLSQRLGALAPPQRFNALLDHIRRHTATILALPGLEAIDAHRGFMEQGLDS
LTALELRNRLSTSTGLTLPATTVFDHPSPAALTHHLLPRLTTAGEADGPGPVRGPGADQG
HGDAGAALLAELDRLERMLTAARAEDVTATGVAERLRSLLDRAHTRSTADGAASVPGGAP
VTARLESATADELLDFIDQELS
>A4FI69|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Saccharopolyspora erythraea (strain ATCC 11635 / DSM 40517 / JCM 4748 / NBRC 13426 / NCIMB 8594 / NRRL 2338)|TrEMBL
MTTDFEPVAITGYGCVFPPDGYDTESYWENLLSGRSGISTPPPRRWEWQKYYAEDRGAED
KTYCKFGGFVDDYRFPAELLGVDEDAVGDLNRTQLMILDTTLRAITSAGCTPERLEAEGT
ALFVGNMLGDDLLLDTSIAAKAREIFPYVNEDEAFRALAPEQRDAIEAGFFDAVHARFPD
PDGVSATNVFEVELAKAVSRVLGLSGPGLVCDAACAAGLAVIDVAVRYLQDRTHHTVLAS
GALGNMSVTGNVAFAKIGGLSETHSAPLDASANGLIPGEGVGTVVLKRLDDAVRDGDRIA
GVIRGIATRCDGKGKAIYAPSSLGQVSAMRRALELADVRPEELDHIETHATSTPHGDQVE
VESLKDLFDGRPLPEQEVTLGSVKALTGHTFSAAGMANLIKVLLAFEHDTLPPTHSYTAP
RESMDLEQSPFRVPTSPETWARREDRPRRVLSNAFGFGGVNSSVCLEQYEPEHHRPAEAE
ARDRRFGPLAVVGVGCVTPFAVDVSEFDEDRAAGAGVTGFPGDRWHRTTEGVWDAERTWR
GGVIDDLDFPWKQYRLPPSVVAELDRSQLLAVMAAGQAFEDAGLDQDARRDAGVFIGATC
GTEAGLTRNLRIRLVEYLSALEQVPEFQALDQATRDRIAAACTDEVLAQIPATRENALPG
YMDNIVAGRICNLLDARGPGLVVDDDACSFGASLDIAARYLEQGECPVALVGGAHANLAP
EFTELFARRIRESGQQTGELVPAEAAVFFVIKPLEQVGEDEYVHGVITEAGRASVDASAR
PDGEPFYFGAQGALQMLDAVTGMGKSGEARWVRTPQLDGGPQGYQVRLTPQGEEPAQGGD
AAAEDGIGFVVGRTATDLLAELERVAAGAARPLPAVPADGHLGYRLGIAHSSDDELARKA
TVALKLLRSAGDTAAPSPAATA
>A0A1R4HIR5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Crenothrix polyspora|TrEMBL
MLTQLLLRAAKATPNKAAVVQGKQRINYAGLHRLAGCGSVGLQRLGINRADCVAVALPNC
PEFVISLFACARLGAVLLPLNPHYTQDEMQRFLVDANAKIIITDLARAALCQQIIAEMAW
PVQLVVLGETLGSTLGFDDLVDNAEPPLPSGMITGNALYLYTSGSTSEYKRLCCTQENLY
YEAHNFVETVGLGADDAILCTVPLYHSYGFGNGLLDAAYTGATLVLLEPVVDNGKIVDTP
FVSRTARVLELIRQEAIRFFPGVPYQFAALAELPPERVVDLSGLKLCISSGDVLPQYTYT
QFLKRFGIAIRSLYGSTEAGSICVNTDPTEHMVFGSLGLPLRNVAIQIRDEHGHIIQGDS
EGAIWVKSPVIPPNGYDNRPELTTQVFRDGYYDTGDIGKQDARGHLIITGRKQTFVDVGG
YKVDIGELEEVLHAHPKVREAAALGVEMVQGGQLIKAVIVAEDGCDQTDILAHCRQHLAA
YKLPRLIEFRDRLPRSPLGKVLKKHLHSQPISLDVPPLSQALHAVAGVPKAQQIAVIADH
LHEQVAATLHVDLTQISRSAAFQSLGFDSIRAAELQNRLVQLTGLALPITLLWNHPSIDE
LAVVVFERLSFDVASARVVEQTPLPVTKQATDEREAIAIIGMGCRFPGGVTTPEQFWQFL
QDGGNGVTEIPKDRWDVEQYYDANPDTPGKSYSRWGGFLAGIDQFDPAFFAISPREAEQM
DPRQRLLLETAWEALENAVLAPEKLAGSNTGVFIGHMVGDYHALLGKQLHLVDSYVSTGV
LDSLLANRLSYTLNLQGPSLSVDTACSSALTALYLACQNLRQRECDLALVGGVNLMLSPE
MQVIGAKAGILSPVGRCSTFSADADGFVRGEGCGVVVVKRLNDALRDNDPILAVVRGAAI
NQDGRTNGIAAPNGFSQQRVIQQALNAAQLEAAQITFIETHGTGTLVGDPIEVEALAEIY
GLASPQGACYLGAVKTNIGHLEGAAGIAGLIKMVLCLQKSAIPPNINFNRLNPHINLDNS
RFQLPLTNQPWGVAQGRRYGAVSSFGIGGTNGHVILEEAPQHTLITSTLERPLHVVALSA
KTAPALSDMVQHYWGYLDTYPDCILPDVAYSLNTGRNHFGYRLALIADSTTTLIDQLQSQ
LAPANAYTLLPVPKIAFLFTGQGSQYFGIGRALYGTQPRFKEALDRCAELLQNELQHPLL
EVLYATDETELINQTVYTQPALFAIEYALAKLWQSFGVQPDWVMGHSVGEYVAACVAGVF
SLEDGLRLIAARGRLMQALPQNGSMLAVMADEATLVKIIAPYSVSVAIAAINGSHSLVLS
GEHQVLQTLAAHLHSDGVDVRPLTVSHAFHSPLMDPMLAEFERVAQTISYHPPSLNLIGN
ITGQPVQHEVCQADYWVRHVRDTVRFADGMVTLQQQGCNVFIEIGPKPTLITMGQHCISV
RDGLWLSSLRPQQADWHSMLGSLAALYERGLDIDWVGFDQNYARRKLALPTYTFQRQAYW
LSGCPVVAQKHSAALRPLVNKIMRSPLLKDRLFETEFNITSLPFLADHRVYGEYVVPGAC
YIATLLSGMEVMGQACCQLQDILFPAAMVLQADESRTVQVVLSPKESTSGGEGITSFQLI
SLVEGDYLSRPQTHMLGQLHGQPAQPATKDTLSQLKARCTTTVDPERFYSVSAAQQIVFG
PSFRWLQGLWQGSDEILAQLRVPDVLGNINGYAFHPALLDACFQVAACTLLDQDEQETWL
PFLIRNIRVHALTMGDTVWCHAKQTGEHVWDIQLFNAQGDVLLDILGFEERPVPSEALLA
RPVWKDWLYTVGWQPQAITQNIPSPLTAHQAWLIFADDTGVGYQLAGQLTRQGCTVTLVF
QGLTYAKIDTHSYSIRSESAQDYQQLFAAQTEKFAVIHLWNFQSHSTGVESEFLSAETDS
ICHQLLVLTHAMSACPKARLGLWLVTHNAQAVIDNDPVNGLLQNTLWGMGKVIHMEHPEL
HCTLVDVASDDSTHLAEQLANEINVGQQVGIEKENQVAYRGLHRYVARLARYQEQIDNKT
PPDLSITGNATYLITGGTGGLGLEVAHWLVEQGARHVVLMARHSAHAEARQSIKNLERLG
ATITVALADIADFNQAAHVFENLDTDYPLKGIIHAAGVVDDGVIQQQTRDRFAKVLRPKI
QGAWNLHTLSQDVALDFFVLFSSLTSVIGTPGQVNYAAANAFLDGLAHYRRAQALPALSI
NWGGWSQVGMAARMEDIERQRLFARGETLITPAQGIEVLAALLGQTNPQIGVFPLQWERY
FDTDHRPSPFFSAVSIEPLTQDEPQKTTKIRWLDTLTTTAKDTQQTLLIEHLRGIIGKIL
RLPTSQKIELRQGLRDLGLDSIMSIEVRGRLEIELECPLPATLLFDYPTLETLANYLAAS
VLGLALETASVPAIDEAELQMDDDLAAFLSGIDQTSDADIQQQLARMKR
>D3DC71|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. EUN1f|TrEMBL
MWAAGGIGPATAAAAVAGGAAGVVLDSQLALVREVELPAEVARAVRAMDGSETALIDGHR
VYVRPDLPVAALVGWAGSSQDGSSADASPGSSADGPALDFRDTGGERASDGALTAGRSVA
AGSVALRLGGRDLRTQLLPIGQDGAFAAELADRHVSASAVVGAVRASIRSSLAAAARHRP
LASGSAFAAARGLRHPVAQGPMTRVSDRAQFAHSVASAGGLPFLALALMSGPEANALLTE
TADLLGDLPWGVGILGFAPPEVRAAQLDAVHSVRPPCALIAGGRPAQSTPLEAAGIDTFL
HVPSPGLLERFLADGARKFVFEGRECGGHVGPRASFPLWEAQISGLLAFARRAQDGPESL
GDVHILFAGGIHDATSAAMVAAAAAPLVERGAQVGVLMGTAYLFTEEAVTDGAIMPGFQE
AAIAASRTVLLETSPGHATRCVESGYVREFLRRRDELTAAGVPRKQMWAELEQLNLGRLR
IASRGVRREGGQLVAVGASEQVAEGMFMIGQVSALRSARTTIGRLHAEVTDEAMARLTAR
AGELAVPVVPNPAQPADADIADTGADVAGAAAADAADAGGQAERAARSVASVRESARPID
IAIIGMSAVFPNAADEKDYWANVVDGVDAITEVPAERWDVDLYYDPDSMVKDAGRRTPSK
WGGFLPRIPFDALAYGIPPRSLRSIDPGQLLALEVAARALRDAGYDDRPFDRRRASVVFG
AESGSDLSTAYGFRSAHRAWVGELPAELEEILPELDEDSFPGLLANVIAGRVANRLDLGG
LNFTVDAACASSLAALDAACKELTAGSSDLVLCGGVDTHSAVHDFLLFASVHALSPGGRC
RSFAAGADGTSLGEGVAVVVLKRLADAQRDGDRIRAVIRSVAGSSDGRALGLTAPRKAGQ
VLALERAYSWAGISPSEVGVLEAHATGTVVGDRTELATLTEVFTEHGAETGQCAVGSVKS
QIGHTKCAAGLAGLVKVARAVETGVRPPTLHVDEPNPYWDRNSSPFYFDDEARPWVAPPA
RRHAGLSAFGFGGTNFHVVVSAYDKAPEPAHGLDRWSAELFLVRARDRAGALRRLDTLAA
QVRANEDAGRPFRLRDFARTVCEEAGGAVQIAFVVDDLDDLPAAIERARDPRSAPRSGLF
VRDGDDHATVLGSGSGSGSGVGVGVGGAGSLAFLFPGQGSQRPGMLADLFVAFPRLRSLL
ELAPDVAATMFPPAAFSDAERAAQSAALTDTRSAQPALGLADLAIYDLLGGLRIRPDHVA
GHSYGELAALCAAGVFDRRDLVRLSRARAEAILAAAGDDPGTMAAVSATADQIRAVLGAP
AADGTVAGVALANQNAPRQTVISGPTAAIDAAVELLKNAGLSSRRIPVACAFHSPVVAGA
ADGLATELAGTDVGAGVIPVWSNMTAGPYPQAPAEIRAALAGQLAAPVRFVEQIEAMYAA
GVRVFVEVGPGRVLSQLAGKILAGRPHRVVATDAAGEPGLRRLLLAVAELAVAGADVDPS
PLFVGRDTRVVAPGAMPRRPGWLIDGAYVRTSDGGHLPGGLLPARRISPTAQAADGEATP
AGPAVLNGAAVLNGAEVVTGAGGDIPAPRHDPGQLGARPGDMVGGSPMSDLRTFDGQLPG
HPSGSAGANGAGPASAGRHPGPDPAAYPALPAGTALPASPAPAASPAPLPAAGPADTIML
EFLRTGRDLVAAQRDVLLTYLGAARQTPTPATSAVPVPVPVPVAAPALAPVPVPVPNGVT
QLSSGPNGHHNGALTTYPAAPVVPAAPEVAVPAVPPLVAVPAEATVAVGPVSAVPASVDV
PVVVPGLSLEAVTESVVGVIAELTGYPVEMLEPDLDLEADLSIDSIKRTEILGELAGRVG
LPGMGAGGAGSGLSEVDESVVEELAAVKTVRGIASWIVERAAPTSPAAVAAVPAPASVMA
SVDVPVVVPGLSLEAVTESVVGVIAELTGYPVEMLEPDLDLEADLSIDSIKRTEILGELA
GRVGLPGMGAGGAGSGLSEVDESVVEELAAVKTVRGIASWIVERGAAGGSEAGGAGSGPA
GAVPAGAVPAGAVPAGAVPAGSGPGDTGRPGTDRAGAVPVSTGRTGGSAEFGGSLGLPEQ
GGGDRPGGGIAR
>D3D834|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. EUN1f|TrEMBL
MRESGPPRRLADTPIAIVGMAGLFPHARDVREFWQNIVDARDCIEDIPASRWNIDDYYDA
DPTRPDHTYSRRGGFVPDVDFDPLEFGLPPNQLEVTSTLQTLSLVVARDLLRDAGATDST
WYDAETTGVVLGVTGPVPLMHPLGARLTTPVLREVVRACGLTEDDAQAIATRYAEAFAPW
EENSFPGLLANVTAGRIANRLGLGGMNCTVDAACAASLSAVRMAIAELVDGRSDMMIAGG
ADTENSIFGYMCFSKTQALSKSDRIRPFDEGADGTLIGEGVGMIALRRLADAERDGNRIY
AVIRGLGSSSDGRSKSIYAPRAEGQERALRRAYADADCSPASVELFEAHATGTAVGDRTE
LTALDGVLRAAAGGQAHFAAIGSVKSQIGHTKGAAGTASLMKLALSLYQKTLPPTINVER
PNGPLAEDATPLYVNTRTRPWIRDPHRPVRRAAASAMGFGGTNFHVVLEEHSALRPANGM
VHRTARAWVWHAPDPAALRAALEAGAAPTDGPIPADHARVGFVTPAGDPDGAEPRRIALA
QLAASPDAEQWTHPAGIYYRRRALADLRVGALFAGQGSQYLEMGLDAVLGVPTVGQALDD
ANAVFDGDATALAAVMYPPPVFDPELRQEQESRLRATRYAQPAIGALSVGQFRYLAELGL
DCSGHLGHSFGELTALWAAGALTDADFFRLARARGAAMAPPDAQASPTEPASSDPGTMAA
VQAGREEIERILADFPDVVVCNHNAPDQVVVGGGTQAVGEVLAELARRGLTGRLLPVSAA
FHTRYVGHAVERFAADLASVEIGAPTAPVYANTAGASYGTEPAANRAVLGGQLLAPVDFV
AGVRAMRADGCNVFVEFGPKQVLAQLTRRILGDEPIAVVSTDGGPLRDGDVMLKQAAVQL
AVLGLPITDINRYDPASHAEGGQAAARRAAMTITLTGAEYIPDSRRALYNAGLTDGFRVS
ALATPTAATPAADAAAVAAVTPATLTSAALAPATLTPTANGAPTANGGSVLGGTATTSAN
GDLSAGSHAPAVDGPPAPNGLAVTGAAAAPVGAAATSPVVAAGTDLDPALVTEAVNRHLD
LHTRYLDGQLQITGELVALLRSGASTDQPAWIPAAIEQVAEQSLAAGRTHTRANEVLAAL
AGLRLPAREDPFLPAPAPPRPRLCRWPRFTRHQPDSPRPRRPVRRPRWCPGSPPRIPVTA
LPSATAAPLATAVRTATGTGPGRRPSAQASPSGPRPRRALLPARRSPRAPRWTRCAPRSS
VSSPTAPATPPK
>A0A0N1GIT2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MASNEEKLRDYLKRVTADLRQTRKRLHDAETSRQEPLAIVGLGCRFPGGADTPEEFWRLL
AEGRDTVADFPADRGWDLDAAFDPAGGPGTTYARQGAFLYDAPLFDSTFFDISPREAMTM
DPQQRLLLETSWEALERSGIEPGTLRGSRTGVFMGTNGQDYLALMLGRPEESDGHLTTGI
TASVLSGRVSYVLGLEGPAVTVDTACSSSLVALHLAVQALRNDECDLALAGGVTVMSTPG
AFAEFSRQRGLAADGRCKAFAEGADGTGWGEGVGVLVVERLSDARRNGHRVLALVRGSAV
NQDGASNGLTAPNGPSQQRVIRTALASAGLTAADVDAVEAHGTGTSLGDPIEAQALLATY
GQDRELPLFLGSVKSNIGHTQAAAGVAGVIKMVLALQHGVLPRTLHADEPTTRVDWTTGA
VRLLRESADWPRTGERPRRAGISAFGVSGTNAHVILEQAPAAPTAEGGTEVDGPSAGQTP
AVPPALRLPSGTVPWLVSARTPDALRAQARRLADSVRARPDADLAGIAAALLTTRSVFEH
RAAVLGDGRDDLLRGLDALADGHARPGLVTGSAAGSGRTAFLFAGQGSQRLGMGRELYDT
YEVFADAFDEVCAQVDATLEHPLQDVVFGDDPAPLDRTEYAQPALFALEVALFRLAESFG
VRPDVLLGHSVGEIAAAYAAGVWSLADACQLVVARGRLMQAVPEGGAMVSLQLPESEVLP
LIEGRTDRVGVAAVNGPRATVVSGAAADVEEIARQVKALGHRVTALRVSHAFHSPLMEPM
LRDFRRVAESLTFNPPRLTVVSDLTGRPADPDELTDPEYWVRHVRHAVRFADGVRALTGL
GVTRCLELGPDGTLSALTAHILPPQNLPGLPPQDELLAVPAQPRNQPGARSFETALAVVH
TRGATVDWTNFLTGATTSPEPLPTYAFQRRHAWLPAGSSGATGIRAAGLGAARHPLLGAT
VELAGAGGVLLTGRLSARSRPWLADRTTAGTALLPESALVDLAVRAGDEAGCTVLEELTL
REPLPLPRRGAVRMQIAVGAADATGRRPVTVHSRPDDDETDQPGRCHAGGPLPAAVAPPP
LPDMGVWPPEGAEQVDVDGELYDPLALHGHSYGPAFRGVRGLWRRGADLFADLAVPDESR
DADAGTFGLHPVLLDAAVQTALSAAPTPGEGHVALPLGWRGVTVHATGALTARLRVTDAG
TDRAALTLTDTDGEPLATVNSLALTAVPVADVTTDGPGPVDGLYTLDWAPIPGGTAAAGS
GGHANTERPDGSWVLLGPNGTALAAHLTTYGIPVRTHPDLAALRAALDDGATPPTIVLLS
LDPADTHADTDSATLATAAQNATSAVLLTLQEWLADERLDGARLAVLTHHAVAAAPDDRV
PDLAHAPVWGLVRTAQSEHPGRFLLVDRDTADALPPAAVRDDEPQLAVRGDAGLAPRVTR
AARPAEQPPAAFGPDGTVLITGGTGGLGALVARHLVTGHGVRRLLLLSRSGPTAPGAAQL
HDELAGLGAEVRVEACDVADRAALAACLAAVPAEHPVTAVVHTAGVLDDGLLTSLTPDRV
AAVFHAKVAAAAHLHELTQRQELSAFVVFSSAAGLLGNPGQGNYAAANTFLDALAQHRRA
AGLPMTSLAWGPWDGFGGMTAALDRTHTARVTAQGVIPLSAAHGLSLFDAGTATGRALLL
ALRLDPGTLRARAETGELPPLRRGLLRVTVRRGAGTGAGQDGDFARRIAALPRARRQRAV
ADLVTGQIAALLGYDSAELVGADKPFKELGVDSLAAVNLRNRIGEQTGLRLPATLVYDHP
TAGSLIRHLIAELGLDGEQAAHEGEFARPDVSTAGDDDPVVIVSMGCRYPGGADSPEALW
RLVAMGAEGLGPFPADRGWDLAALYDPDSDRPGTTYVREAGFLYDSGEFDAELFGISPRE
ALAMDPQQRLLLETSWEVFERAGIAPAALKGSRTGVFTGVTYHDYASGMQSGTAGNVAAG
RVSYAFGLEGPSVAVDTACSSSLVALHLAAQALRAGECDLALAGGVAVMAQPDPYVAFSR
ERTLAADGRCKPFSAAADGTNWAEGVGLLLLERLSDARRNGHTVLARIAGSGVNQDGASN
GLTAPSGPAQRRLIRQVLAAAGLNSADVDAVEAHGTGTPLGDPIEAQALLATYGQDRPVQ
RPLWLGSLKANLGHTQAASGAGGIIKMIMAMRHGVLPRTPHTGQPTPHVDWSAGAVELLR
EDVPWPHGDRPRRAGVSSFGISGTNAHVIIEEPPGDGEATASDGTDTPADARNPRTAGAA
EAVGDAAPEAESLPGGSGAPSLPGGTGVPSLPGAIPLPLSARSPEALRGQAARLYDLLAH
EPAPRLQDVALSLATTRSALDHRAVLAVSDHDSALRALKALADGTAPDAPVISGTTRTGS
AEPPVVLAFPPADAEWTAATAQLADTAPVFTDALAACGQALAPLVDWTPADVLAGRTAPD
WRQRPEIAGPLGWAAAVALAALLRSYGIEPAAVTGQAQGEIAAACVTGLLPLETGARLAV
HHATTPDEAAPSIAFTTAEIPYCSATTGSWLDVGAEQDAAQWAATLGAAPAAGAEQARQT
LLDSGHRTIVVLGAPQPAEDPDQLPLTTTPDGGLDLTTLLAHLHTRGATLDWTAVFAPTG
ARRVPLPTYAFHRRHYWMTPAPQPTAASSPATDSGATAPHPLLDSTVELPESGGLLLTGT
LDRAARPWWTVPAADGTVAVPATTFVELAVQAGDRVGCDRVVELTAEAPLLLPEEDEVRL
RVSVGAPDGSGERTVRIYSRTASALPGTPWTR
>L8N086|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudanabaena biceps PCC 7429|TrEMBL
MNSHQNGLEIAVIGLAGKLPGSPTIDDFWKNLETGVELVTPFSKFSKSQSSPQEADAKDI
PLSAKIPRFGSVLQDVDQFDAAFFGFNPREAEAMDPQHRLFLECAWEALENAGYRSETES
SPIGVFAGVGMGTYLLYNLSPNPNFIESRGFLQTLVGVDKDYLPTRVSYKLNLKGPSMSV
GTACSSSLVAVHLACQSLLSGECDMALAAGVSVKVPQNESTLSPEEIVSPDGHCRAFDCG
ANGTVGGNGLGVVVLKRLEDAIADRDYIYAVIKGSAINNDGSMKVGYTAPSQEGQARAIR
AAQMMAEVEPDTITYMETHGTGTALGDPIEVAAMTQAFRVATDRRQFCAIGSVKTNVGHL
DAAAGITGFIKTVLMLHHKKIPPSLNFTAPNPQIDFANSPFFVNTQLTAWEPQGIPRRAG
VSSFGFGGTNVHVVLEEAPAPMAVTDLKPRAYQILALSAKTETALAKATANLGDYLNQKN
ELNLTDVAYTLGIGRWALPHRRVAIAQTLADASQILQQPERSLTGHAEANNTAVMFMFSG
QGSQYLNMARELYMSEPTFQAECDRCFSILSTQYQIDLCSILFAEGEAMPSAKQKLTQTA
IAQPAIFVIEYALAKLWMSWGVKPQSMIGHSIGEYVAAYLAGVFSLDDALALVALRGSLM
QQQPQGAMLAVSLSSTDVQSFLGADLFLAAVNSPSLCVVSGAIEAIAKLQHALSAQEIAC
QPLHTSHAFHSPMMEGAIAPLVEHLQKMTLHPPQIPFISNVTGTWITSASATDPQYWAQH
LRQPVQFSQGIAELLNNADAILLEVGAGRTLSTLAKQQSSDRLILSSLPHPQDRSSELEF
LLKTLGQLWLHGVEIDWAEFYAQQPSARVPLPTYPFERQSYWIEAPQIESNARPAIDLNK
KSDLGEWFYFPSWKRAALPMRKELSDRCWVIFGDRQGLGATMTQSLQQRGYRVIQVHIGT
EFSRSDNDIYQINPSDRHHYEMLIREVLTLGQSPIIAHLWTLGDRLDGEESQRLGFFSLL
YLAQAIGQQNVTEAICLGVVSNHTQDVSGTEVIFPEKATILGACKVIPQEYPQIACGAID
VAIAADPENKPDHQPEHKQWCDQCDHIVAEILNLADRPSAPIVAYRGNYRWLPIHEEIYL
PSVTPPSDRTTDRRTERRTDQTAFRHRGLYLITGGMGGIGMTIAEYLARNFQAQLVLISR
TALPPRDEWERWMQNHGDEDSMTVKIRKIQAMEAHGAKVMVLNADVADREQMQSLRDRIQ
QTFGKLHGILHTAGVAGDGIMQLKDPAVAAQVMRPKVQGTRVLQQTFQNDELDFLVLFSS
LSAVLGGLGQVDYCAANCFLDAFAAQSAHSNLRTISINWDIWQEIGMGADLKGLPDRIKQ
ERLEALALGIAPQEGLEALQRILHNDYRQVLVSTKDWSSVLKQRQQNNMALQQPDAPATR
ANAQADSQVSLPSAIGVAGHQRSLQSTSYVAPSNAIEQKIAKLWQAQLGLEQVGVNDNFF
ELGGHSLLAVRLVSQIREMYPVELSLRTLLSDAPTVAGLASLIGEQLLQPEDPDEMAKIL
AEIEKLSLDEIQAQLAQVQD
>A0A2X2M6V9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces griseus|TrEMBL
MHALSSRRLITRAPAVFKIILPSKANDGPVEHDMTLLDVLLDAVREAPGQVVVHVRGDGG
ELTVSLSELLDESLRVAGGLRAAGVAPGTCVPLLADRSEDFQPMFWGAVAAGLVPVPLAP
DARRVLPVWEHLGRPPVVVDASTASLSGELPDDVRALSLDVLREGPALREPVAAGRDDVA
FVQFSSGSTGAPKGVEVTHGAVLANLEQIRAASELGPEDVVVSWMPYFHDMGLIGTHLAP
LAARARQVKIGPLSFAKRPRLWFEVAARHRATVLSAANFALALAVRRVPEEVLARLDLSA
VRLVLVGAEPIAPAVWRAFADRTRPSGLAPAAAQPVYGLAEATLAVTFPPPGEVAEPLVL
DRASLSRGVAVDAEPGDEAVELMDVGRPVAGCAVRIVDDAGTVLGDRRTGHIMVSGPQLA
RGYHGLPDVSAEVFAGGWLRTGDTGFLRDGRLCVTGRHKDVLFLNGRTFHATDLEEVAAA
TPGLPSGAPAVVGSTDPVTGAERVVVFVPWARPAREASEVLERVAARVREALLHDDVRVL
ALPPGAFPRTTSGKLQRRRLRERFEEGVFGSGERRAGEPGAGEVAAGAAGGPPFTEPGRP
AAEPRALAPRTRAETVEVVREAWARVLGRPADAIGTHEPFGSIGGTSLKAMEMLVALEDA
FGVTLPPAVARDHDTVAALAGHLLTVAPGPVLPLADSAKASDTSETSESVVRRTGGTVGG
RAPALPDPADAATAVIGMACRFPGADTPEAFWDLLVDGHDAVAPVSRGRWDDGHAAPGAR
TAVPGVAGVPGVPRERWAALLEDPAAFDADFFGIGEDEARTLDPQARIFLELAHEALERA
GYAGPRRHGHRIGVFAAVGDSGYREVLERARAEGAPLPAALTGNLPSLVAARVSQCLDLD
GPALAVDTACSSGLVALHLARRSLLDGECDLAVVGGVNLHLTSAPHRLLEEAGALSPTGR
SRAFSSDADGFVPGEGGAAIVLTRLDAARRADDPVLAVVRGTAVNNDGRSMSLMAPNPLR
QREVITRAYEAAGVDPAAVTYVEAHGTGTAVGDPIELRSLAHAFPQRPGGEPRLVGSVKT
NIGHLLNAAALPSLVKVVLALGHRRLPPSLHHTPASPGLAPAGFSVVTKARDWTSTGPLL
AGINAFGFGGTNAHAVLEQAPPPAAPASPPTGEAREVSVEGPHLLTLSAHSPGALRDAVT
RLATHLESRPLLREGDVCRTASTSRDEGPHRLAVIAHGDLRERLAAVSAAGTGEAGGRGG
SPVRSRPRVVFLYPGQGSRFPGQDRALYRTARVFRDTFDEASALLGPVGGRSLLDWALDP
EVDAAARDATEQAQPLLVASGVALSRQLRAWGVEPDAVAGHSVGELTAACVSGVLTLREA
VSFAAERGRLMEAFTEPGAMIAVRGGEEAVAAAVAESDGALTVAAYNGPGLQVLSGGVRA
VESAAARLEGLGVPTRRVRVSRAFHSPLMRPVADRIAEAARALTPRAPSVPLMSTVTAEW
QPVLGPEYLRDHAERPVLFGAAVERLAREGYDTFVEVGHGATLSGAVRAATGVAAPAGVG
GAGASGAAGRPATVLCALPGRSESRADAERRSSEDGHGGRGDLLATIGRLWSHGVPLDRT
ALDAEHRGIPLPTYPYQRRRYWADPPASPLLHRVLWEDSALPGQTARAVRSVLLTGPDPA
YVAGLASQLADAGVRTHETGDGPPDAVVLVAGPAPGQDTADALGRAQDTALAAFDEALAR
FDETGADRLLVLTEDVHATGAVRERPRPAHAVLGGLLMALPQETSGASATALDLCSLDTP
SQRLAAVLAELAEPAASSGPRGGAALVARRAGRRLTRRFAPLPSGAAAPAGPGRSPLPPD
GTYLITGGGGGIGASLARDLAGRGRPTLVLAGRSPGLPEGLSEELRALGATVDYRMADVS
VEQDVEALLAGLGHLDGLFHAAGAVRPGTLRDRRAEETAEALAAKTRGTLLLSLALRRHG
LDPAVRVVFSSVSAVLPGLAGALGDYAGANAFLDAFAASERHAGRPWQSVNLAAVAGTGM
AAALGTGAWPATGGGPAAGASAGGRPVALRPALAALRTACGVDAAQLLLADLTPFREPTV
MTDRTAPAAVAGPGDSPASGTDSSGTVSGTAQPPGAGPRTGSGPRGDTAGGTAALLRRLL
ASALRLPDAAVPDDEPFLALGLDSLAAVDLVRQLERELGRTLPATLFFEYRTVAELAAHL
DTTPSLLRSPASAPPAVPDGVAFPLTPVQLALHTSSRLHPDVPAHGYVRQTVRGPLDTGL
LGRALTALADRHAMLRIRVQQTGSLGSGDDGISGGTGSATPGQYVAPPAPLSAWYEVREP
AGRIEEVETALCNRPFDLSAEPPVRALLARESPELSHLVLVIHHAAGDGYSLNVLAGELW
SLYTSLAEGQAPTLPALATDFARYAVATAEARSATDGTRALAADRLYWSGRLAARGEPLR
LPYDGDPSALPAAPVNTHQSALGPVPTAALERRAAAHGVSLFHLLLAVHVRCLARWSGQR
EIAVNVARARRDDRMAGLDRLVGPLADTLPLLCATDPDEPVETLAERLAGIWLESERHAS
LTGLDLARLLPTDPSGAGPRTVSPAGFSFSRFPAALDGRCPVSVRPTAAGTATAATRLSL
LCWQDEAVLRFSWNFPARLFAPATVARLDRDFHAELTALVEPRPGLPAVPGPVQVPAPGT
GSATLVRRLVERFRATPDAVAVDTGATTLTYAELDRASHALAASLLARGVTGGSLVGLLT
EPGADTVVAVVAVLRAGAGWVPLDPGHPAARLTDQLTRSGARTVVCHAATRAVGEALGDV
ALVVADVSALAYRGAGVPGSVPGPDRVAGTLRSPEAAPAPDGPADADAIAYVIFTSGSTG
RPKAVPITHRSMENYLDWAIGTFGYDEHDRLAQTASPCFDASVRQLLAPLLVGATVVTVA
WDLLRDPDRLLTHVVRGRITVWSSVPTLWEQLLSASEERVRNGAPPPDLSALRWIHVGGE
ALSPAHVRRWFDLFGDGQHIANLYGPTEATINTSCHIIRARPGDQVRRLPIGRPVAGTEV
EVVGPDGEPAGPGEAGELLISGVGLTPGYLGEPALTEAAFTVRRGRRWYRSGDRVRCSED
GVLEFLGRLDDQVKIRGNRVEPGEIEAVLQTHPDVAHAVVLAGDGRLTAFVTPGPGAAGA
DAAGLRLHLAQSLPAYMLPSRITRVDRMPLTGTGKIDRRALPALQEAAAPPGADTNAGPA
ARTGDVRTPPRTPTEVRLAAIWTALLQTDDVSREDDFFVLGGDSLLVLEVFARLEKQGGP
LPRPTVVYRNRTLAALAAAVDVAAGAAAESGEPTGVAARAAADPSAGEPGAGDDRTGAPD
PSVTPLPFPLTPTQRGFLLAEAIAPGATSSWLTRLRLHGRLDTARFQSAVDTLVERHPML
RTVFPAGARPAVQQELPSSLRLPVDFEVLTDPAQVEERVTAERARRFEPWAWPLMRLRVL
TTAPDEHVLVAHAHHIIGDGYSAALLVRELTAVYDALSRGEEPASGRPRSTFRDHALHLA
ARTDARTAPPAATASGTTAGRDSVAPAKSPRQGVPAVQDRWERLNAPYAQPRLAAGTTTA
GAPRDAVAPLFHTCGFTVEADRVEALRGLAARTGSTLHAPVLTAYYRALVSATGRADLVL
GMAVSGRDHALPDAHRVFGPFATAVPLRPAGPASGRPGSADFDDDLRRVAAEAAEARTYE
GPVPPLSNGLPMTSQFFFTYLDFSALGPEVGRTLTVTREGGDSVYTPPPAGTDVFLAAAP
EGGRLRITVRAAATAFTPKALAAFTDSVRDGLARAAASTAAEAGRPDRPASGRDGRMDAA
LVGYLPSPADLARLAGLPETALPREQLRTLLFPDGLPRLLETLRTPLGRSGFVCVPLFAD
ELAPGDDLLGHTTRGVELASSLGARAVSLAGMIPSLTGYGFDVLRAVGTTEAVTTTGPAV
TTGHAATVLSVVRTVHAALDATGQRLGSLTVAFVGLGSIGSSSLELLLTRSQQPPARLLL
CDVPGSGPRLKELAESLLERGLVEVVEVVESGHGLPDAVYDARLIVAAVSGGGALLDIDR
LAPGTTVVDDSFPHCFDTSRAVGRMERSKDVLVVGGGLLSAGPAERQVAEGLPAAAVAGY
LARPMVPDTIASCRLESLLHASGAGVPLVHGPVDAATGLAYWEAAEATGIRAAPLHLLTR
TVDPDMFTRHPWSS
>C6C2W0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Musicola paradisiaca (strain Ech703)|TrEMBL
MMIGKENRTRDLHESARNILEAELMQSAMEYSPTLSNTAGAVQDSPFSEVNGGDYRGILL
QDIVGIFSAILKLPTAKIDKEEKISTYGVDSIVITEIMGRIADSLGVSLSAAIFFEARNI
EELADIIIKRFGQEVVQRYDGRPVSEAHQSAGDERRNDVRQPVAQSLPSGTTSARGIREL
MARSHRLNQKRDQFHSTHDKCQSTDNAEVNKPGGHDEPIAIIGMDGRFAQSSSVEALQRH
LYQGQDCISEIPQERWDWKAIYGNPKDGEFTNVKYAGFIEDVDKFDPAFFGISPREAQTM
DPQHRLFLESSWRLIESAGYAPSSLAGKKVGVFAGINLQDYAETVLNAQSRDIVELTAIP
HMFCPNRLSYLLDVHGPSEIIDTACSSSLVAIHRAVMSIQHGDCDMAIAGGANLILSPKM
HILYSKAEMICEDGRCKTFSEDANGYARGEGVGVVLLKKLKDAQADKDNILGVIIGSAEN
HGGAATSLMAPNPKAQAQLVRDAHMKSGVDPRSITYIECHGTGTPLGDPIEVNGLKLAFK
HLYQEHGLDPEANAGKAVEKHCALGSVKSNIGHTETAAGVAGVIKVLLAMRDEYLPQSLH
CQKLNPLLELEDSPFYVLQEGQTWQRPTIGFVQQPLRAGVSSFGAGGSNVHLVIEEYRQE
PDKVMSPEREPEIIVISAKNSERLRIYAQRLMQYVTENSANVANHFKQFAYTLQTGRDAM
DARVAFVAEDVASLSRQLAIIARDPQAAAGEGTIFVNCDAATRLPGIDAQDIAHWWQTRQ
WTKIAQVWVETRAIDWLQLYAGQRYSRLALPTYPFDRQRYWINETRRKSALERAVEQPTT
EPVTAHHAVKVNDAGKMTLQPLMLKSAVGPSVSATERRNGKTADSHQGRGINGVATDSQI
TSSARGINGSGNGTLHPAQKSGGVPLASVIETLRVSLARALCSPETEIQLDRSFAEMGLD
SIVGAEWVHEINRQLGSALSATRLYDYSSVRQLAQFIVLNGGQRDAADEHLPETDNRAVF
QPENNPTVTEPSNAVIHSPQAAHSPQAAHISSGQNEQLAEIIQRLKTSLADALYITAEDI
QNNRIFSELGLDSIIGAEWINTLNKQLGTHLSATRLYDYPNIHVLAEYIATQTHGITLPP
KPVAATSTCIPEHEDLPRNTLKLAAPVSAAIPEDDQGIHRQREKIAIIGMSGRYPDAENL
EQYWDNVANGRNSVREVPKARWDVEHYFDADRSKDGKIYCKWLGALSDIDNFDPLFFSIS
PAEAEGMDPQHRLFLQEGYKAFEDAGYSPEELSHKKCGVYMGIMSYEYAHMMLNSAAPLS
GTGNSFAIGAARIPYFLNLKGPAIPVDTACSSSLVTTHLAVQALQNGEIDLALVGGVSLY
LMPETYIGMCSAGMLSAEGQCKAFDNTADGFVPGEGVGCLVLKRLSQAEADGDPIYGVII
GSGINQDGKTNGITAPSVNSQIELERDVYRKHQIDPDSISYIETHGTGTKLGDPIELEAL
ASVFREWTPRKNFCGLGSVKSNIGHTSAASGMASVQKVLLSMKHRQLAPSLHFSTPNPHF
GFDESPFYVNTQLKPWLHDVRQPRRAAVSSFGYSGTNAHLVIEEYLPPSVNTAPVTEPVL
IVLSAMRADRLPLMAENLLTWLQREQTDERHVDLRRLAYTLQRGRQAMEERLAFVAGSVS
ELQEKLTQFIAGDISAPPLFRGRVNYHAPSYQAVIDTPAFSAVIEQWTRQQHLNQLAGLW
VTGLDIAWELLYPRSEQAAAHRFPGRIHLPTYPFFKQSCWFEAKAKPTSVVSVEAHLPLS
EASEAVRTSEAVRTSEATEIGANAQPIAKETQWLRATETWVDVQSNEDTPWVERIQASSD
RQILVLSHADSDYRDIEQVCRQVQHIADMPQSIWGVRHIPLPDGAPQDKWGIDALKVGLS
AAIPDSDKPLVVFLILPHGTEAEAGHGLQLAYLCVQAVQAFARLNPVQFYCCHRADYEQS
LTVTDVQHEALSGLFRSAMLETVGHRYRSLIVDPRSTGQEVALQLIQTWLCDDLSEHEPG
KNAQAVRTPTVRFSAGRRYELRVSETDAPAVPGACFRTGATYLMVGALGETGEQVCQVLG
QNYQAQLVIFSRRLENQVAPMLARIRASGARVIYRTVDILDIASVKQAMQTLKAEGITLH
GVIHMARQVSDGSILNKSWDAFRHMMAAKVSGTLNIDAVTAGEPLEFFLMFSSVAAFGIQ
GSPDYAYSAAFQNAFARYRQRLVALKQRQGLVSSICWGQWDVDGAVDSTRLAGRLASLAQ
QGMGSINAVAAVQQMQIGFTDSVTALVAVTDRRKARTLLGLSDHQTESVTARPEHHTVEA
VRRQIHHFRLGQLSPTAFADYLSSLSLADLPADLQQEVGTVITAARHVPQTLNTTALSAA
QNARPATPGDNEGIKPAENDGEIRRVLASGIEKVMKLGSDLDWDKPLQDYGMDSIIAMQL
STTLEKQMKFPVQPNWLIEHPTPNLLLKKLRNQVGTGAIRL
>A0A1V2RBR4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MLRRDRPEPDSLMQAVARLHHRGVGFDWPRLFAGTGAKKAALPTYAFQRDSYWLHQDPGA
AGHGPGSTGHPLLGTAVTAAGSGEVLFTTHLPPHTHGRLTDPALPDAPVVPASALAEAVL
RAAGELGAGPLERLAVHVPLLLPEHGAAQLQTAVGPPDDAGRRPFAVHGRHGDGEAPWTL
HADGVLGAAEEPPAPAPAAGRGREASAEAALPEELLPDAAAYGIHPALLEAAVRTAAGAA
PAGTVRVPGEWLGVRLHAAGATAVKVLSADAGADAGADAVSLRLTDPAGRPVLSVDRLAF
RDVPEARFAAAAGADRSLYAPEWTALAPAPQGEAVPWAVLGTADVEGAAFEDIAGLAAAL
AAGAPFGAAVTALGTGPDAPAEALDLARAWLAEERVTGLPLVVLIRGGAPVTPPRPDGTG
PEGRVAAAWGLLRGAQAEAPGRFVLIDVEDGRVPGELLSAVLASGEPQAALLDGAARVPR
LGRAADPGGPGGAAPEPAVRFDPDGTVLITGGAGTQAALLARHLVAAHGVRHLLLLDPRA
EGTWPEPGLLEELGRSGARVRALTCDTADRSALGAALAAVTPPLTGVVHTAGAEQETPLP
HLTADRLAAVLRSGADTARHLHELTRDSNPAAFVLLTSTAAATGTPGLAARAAADAALDG
LALHRAALGLPVTSLALGPREAEAPAPREGFRPLTEREATGLFDAALRAGPATLVALPLD
PGAMRAGRGVPALFRRLVRAPAGPAAAGTGVPLAERLAALPAEQRHPAALAVVRAEVAAV
LGRSDPGAIEADRAFKELGFDSMIAVELRSRLGERTGIRLPATLAFDHPSARTLAAHLVT
LLAPDAGPAAQPPALAELDRLEAVLAAGPQDEGERGAIVVRLQTLLARLTETTGGEDAPA
PADGIESASAEEIFALLDGRPGGPAD
>A0A3R7YU40|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii CAST|TrEMBL
GRRSEVEEVLSFFSISGRARFLRVSHAFHSPLMAGAVEPVSRLFERVEFSEPAIPFISTV
LGRLAVGSELSDALYWSEQITKPVRFREAVVAAFGGAVAGLSAVEVGPKRTLANIGAACV
NGATHPGCAWLCVIEGPATSESGSQFESFLKQVASLSSRKLHWNHRTFPLARLQEQKTEV
AGQNLRSMAKPSPHSQPSIWSEKWAYHSSVPENDAVFKVPKKAWIIVGVPSQHMAEVLLS
LKRMGLDTSRVCGLGAISSLETLQNLVQGGTWAGMLVVSGLWATVSAVESLTETAHILRH
YACLSTEIEVPVLAVVTRGAQRSVVSPETFGQRERPTLESVPQQNQVFGHLEDEVPVHAG
LLAFCRTLRLEMGRCCRRFKPFLYFDTDRLHPRQSKESLDYHLGAVLKWLSRNDVPASFS
EQIRPDSDTLREWDIVIRKQSYFVPRVAPVLLKQPSTTAAGRIQKAKSYIVTGGLGGIGI
VVASWLLRQGAGRIFLWSRRGVPTDDVKETNQWCELNAAMETGRIQTVSCDVSEIEQVRH
SIVLAVTDSILGGIFHCAGTEGKGKLQDVSQQDIADVYASKVEGAWNLHRICSEMSINTN
LDFFVLFSSIAALPGNDAFATYAAANGCLDSLAEHRRSLSLPARSIQWGPWLDAGMAART
PSFERFMRSRGIRGFHNEEAISHLETLLTADESLTCCAAVHVDWRIYAHIFGSHVPTWLQ
DVVPGLQTSLTPFSESNVPEQMHGSMDIQGVESAVIDVARRLCGAEGIVSASTEISSLGL
DSLGAVEFRNALQEALKIKLPASLLVEYACLKDIIQFIMENCFSDAARSTSDLVPLVTRE
PAANDQGFAVVGMGCRIPKNATTTEEFWDMLLHEIDAVCEIPMDRFNIDAFYDPDPEQDK
CYTREAALLDHPDFFDNTFFNLSDQEVLAIDPQQRVLLEVAYEALFEAGFTKEALLGKDF
GVFCAAYNNDFQFTNLTQGKATMCVFDKGEGRGRIPSLGEAAGYPEPGGFMCFIPNRISY
SFGLTGPSIGIDAACASSLVAFDAAVTKLKRGACSGALVGGVNIILSPTFFLGGCKAHQF
SRAGRCKTFDCNADGLVRGEGCGAAFLLPLDAARETGAFVHAVVRGSATCHYGRSSQITS
PNTRALTRVLRLSLQDASTAPSLVRYYEAHGTATVLGDVIEMSAVKDVFQTGRNAAAPLH
MGTVHNNIGHLDAAAGIVAFLKTVLCLKHRFVPANIHFKSLHPDIHGIDTQLIKYTRESH
SIMTDNVATGVRKTIFGANLAYGMGGSVAAIITESGDEEADRRSLKAAPRHVWNHRRFPL
NTQKFVYLMGAMGQISMDDMPTPHSDVIHVMKRLSATALNVAFMRKLSPSTCAAGSIRSV
FLTGATGFIGSQVLFHLLQVKRQDPKLGTEDKKLTIYCLVRARDRAHGIYRIRDSLVGRG
IEWKHEFDQQVIPVIGNLEEGENMGLGTKQMQYLEQTVDAVYHAADNVNFAAPYDALRKS
NVLSLIPILKLCTTYVAKPLHLVSNFAHHLQYFAGFSEDLNIAVDETVSPPLSPASIDRL
EQQMPAGIIGYPWTKWAVEEIIGRMKDVLHERCEEEGQRVSMEESEKKDILSKFQVTVYR
LPNSCVYYNNGYTNFANASLSLVLASAQERMIPPGVLPVGAPFLTTPVDLITGILVKLSM
TERKRHHVYHLVSLRVARRKHVVQAIKWLFPDSVECTADELFRRIDENKENSPAHPLRAA
MRFWRRYWYSSDTDRDSPFPVAVNNVEDDLPGVMATFPSLADTWLRMASYCVKNYHMVRH
PFTLAISFERLKKAIAGITKQRIDELALPSQTQELLNETCSTEDTTDIAAVKALVEHANL
RKYDDCAVSDVPDPRARA
>A0A378SYZ5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium senegalense|TrEMBL
MSSSGKPPEFGAADPVVIVGMALEAPGGIETADDYWSLLTEQREALGRFPGDRGWSLREL
FDGSRRDGFKRIHDLGGFLSTAATFDPAFFGISPREAVAMDPQQRVALRLAWRAIENSGV
NPDELAGHDVGCYVGASGLEYGPALTEFSHHSGHLITGTSLGVISGRIAYTLNLCGPALT
VDTSCSSALTAFHTAVTAVRAGDCDMALAGGVCVMGTPGYFVEFSKQHALSDDGHCRPYS
AHASGTVWAEGAAMFVLQRKSAAVRNGRVILAEVRATAVNQDGRTTGLTAPSGDAQQRLF
AKAIRQAGVRPEDVGMIEGHGTGTRLGDRTELRSLAQTYGATAPGAGAVLGSVKSNVGHS
QAAAGGLGLAKVILAAEHAAIPATLHVDQASREIDWDAQGLRLATKQTPWPAVDGQRVGA
VSAFGMSGTNAHAIISVPEVAGEAA
>A0A679IV34|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Methylobacterium bullatum|TrEMBL
MVSSIKSVCESNVIKRTDIAIVGRSCRLPGAASIDGLWQLLSEGRCAVGRIPEDRWSLER
FGHPRAQERGKSYTWSAGVLDDIWSFDPGVFGISPREAEQMDPQQRLLLELTWEALEDAG
LRPSAVAGSQIGVFVGASSLDYGNLRVLDTSSGDAYAATGNTLSILSNRISYIYDLKGPS
FTVDTACSSSLVALDAAVAAIAGGRIDTAVVAGVNLLASPFNFICFSNAQMLSRTGLCQA
FSANADGYVRSEGGVVLVLKSARQAARDGDTVRGVIAASGVNSDGRTTGISLPSGYAQGA
LLEQVYREAEIDFDAVAFVEAHGTGTAVGDPIEAGAIGGKIGRPRKEPLPIGSIKSNIGH
TEPVSGLAGLLKASLALEHDLLPPSLHAAELNPDIPFTKLNLLVVTAPLTLPRGRGERFA
GVNSFGFGGTNAHIVLTDGAPAPAASDAGRPPELLLLSAQSRAALNELALDYAERFEQAD
EAQTVRIAAAAAHRRERLSTRLAMPLDADLPATLRAVADAEETDIARVGTAVDRNAEVAF
VYSGNGSQWVGMGREAYERSAAFQSAFDRIDVLFAEISGWSLKEALFAEDLAERMVLTRV
SQPLIFAISSASTTALKAAGLVPSFVLGHSVGEIAAAEGAGILSLEQAVKVIFYRSQHQE
TTRGLGTMAVLLAPVEEIEIFLKDYPSLDIAAYNSPKAVTVAGPVADIDEAMKALARKRR
RGRKLDLAYPFHGRLMNPTEKPLLRDLAGLKPYPGAIAMVSTVTGTVLPGGEFDAGYWWR
NIREPVRFSDAVQEATRKGARIFVEVGPRATLLPHIGDCIEPLGIENATVGVLTNKPVGS
DPFARALASALVHGAAVDEAVVFGENPKGDVALPSYPWQRRPFRLSETSEGVGAATARTY
HPLYGSRLSPDGLEWLGHVDIATVPDLDDHRIDGQAILPGAAFIEMALGVAREAMRSDDV
VLAEFEILSPMVFAEETLREVAVRLSGSGNQIQILSRPRLTQAGWQLHASAKVVDGTFAA
RPRQDIDIPAENAVEGAGLYRLAAASGLDFGPSFRQVALSARVDETTIVSQLKPAEADLR
FGLVPARLDACFHGLILLFADLMGEGSTKAYVPVRFGEIRLIRPGAVIARAMIRTRRCNE
RSILADFTLVDEAGEVIATLREGRFQALRTKSGQDLAAYAIAQRSELATEPTAIPLDRRA
RIADAVRPGIKAALAPADAALSPGHLLLEGWATSLAYRMAEGLQRSGTVAIDERVPEAMR
PWLLNALYALESSGLATLDGTRWTLRKDVTLPAPDEIMRWIAADHPELSAELVLTADLGA
VVARLVASELASPPTLPQNALDAFVLRSATARASSDVIAAICEGARADLPKDRSLRLLQV
GFGPLSAQAAAIADGIAAQLTVFETDRRLAERARLALPRGVTVIEDETDLTEGGFDAILA
SNVLHRSERGLLGKVADALATGGFLLAVEPGASLFRDLVFGLMPDWFESVDGMPLGRLDD
IAGWQRSLSDTGLVRIAVDRAASANGDDLLFLAEAPVRLKASTGQTFTFIIGSRDSFAAE
TASSLATLLVAAGVHVSIILDSEQSLLELERETPDTVVFLAGAFGSGGEAADRLRERCLG
LKRCVEHLGTRQTRLWVVCPGATRHDGAGAVEAGLWAFTRTLANEVANLDIRRIDLTEAM
PTKFASERLRDVILSGTLETEIVLDVDATRVIRFSPGQLSRRPAADAVAAPASQLERSAT
GGLNDMRWGPAERRVPGRGEVEIAVEATGLNFRDVLWALSMLPEEILEDGFAGPRLGLEV
AGRVVSVGKGAAAFKVGDRVVAFAQSGFSTHIVVPELVVAPSPPGLDPQAAATVPVAFLT
AYYSLVSCARLRRGEWVLVHGGAGGVGLAALQIAKLKGARVIATAGSREKRALVKALGAE
HVLDSRSLAFVDEVRRITGDGVGVVLNSLFGEAMERSLNCLKPFGRFIELGKRDYVANTH
IGLRPFRRNLSYFGVDLDQVLQHQGEDGARLFREVMALFTEGGLKPLPFQPFTADEVSDA
FRLMQQSGHVGKIVIAPPKPGSIVVERKSDFQVSAEGVHVITGGLGGFGIEAARWLADRG
ARHLVLVGRKGASSPEAKQVVADLAVRGVSVAAMACDITSRRAVEDLIEEVESGGRKLAG
VIHGAMVLQDGLIANLDAASLDAVIRPKVVGAEHLDAATRGRALDYFVLFSSATTFIGNP
GQGAYVAANGFMEGLARRRRALGLPALAIAWGAIGDVGVLARNRAVMETLAGRVGVTPMD
ARRSLDLMAEALEGQGSSPDDAVLAIASMHWGKARERLATMRSPSYGDLGSDQQAEAGTV
ATIDIGGLLKAQDLDAVRKTVSDAIVEDIARILRLPKDDISRVRHLSEIGLDSLMGVELG
ASLQERFALDAPPSGISSGLTVVELAETLIQSVAAPVDDASAAVMSLAQRHASEGVDVRT
LEPFHELVEQNSLQIKEILP
>K4QXG1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces davaonensis (strain DSM 101723 / JCM 4913 / KCC S-0913 / 768)|TrEMBL
MTGPGQGGTSADTLRRAYLTMERLQRRIEEYERAGSEPIAIVGVGCRFPGGVNDPDTYWQ
LLTDGVDAVRDIPADRWDNEAFYDEERGRTGVINTRSGGFLDRIDRFDHDFFGISRREAL
AMDPHQRLTLEVAWEALENAGQAPSGLAGSRTGVFMGVASSDHVASRIRYPEDVTAYTSS
GAALSFIPGRIAYLLDLRGPNVALDTACSSSLVAVHQACQSLRTGECDTALAGGVNVVLS
PVLLISQSAFGSVSRKGCASTFSDDADGYVRGEGCGVVVLKRLSDALRDGDRVLAMVRGG
AVGQDGRSSGITAPNGAAQREVYRAALAAGGVAPHQVGLIETHGTGTRLGDPIEAESLAD
VYGRPDGPPVYLGAVKTNFGHLEAAAGAAGLIKAALCLAHGTIPPNLHFTRLNSNISFEG
TTFTVPTRVTDWPEPDDSPRFAAVSSFGLSGTNAHLILEQARSAPAVARDELRPASVLPL
SARTETALESLARRYRDRLRATDDAPLADLCHSAGTGRSHFRHRLATVGATREEVADRLD
AFLRGEDGPGLAHDEAEDTEVAFLFTGQGAQRAGMTRRLYETQPTFRRTLDACAEILRPQ
LERPLLSVLFPDDPADDRINDTAYAQPATFAVEYAMAQLWRSWGVEPAAVIGHSFGECVA
ACVAGAMSLEDGLAFTVERARIIEQFCKPGTMAAVFAPEAEVAARIADDLDRISIAAVNG
PANTTISGERDLVEEICAEFTARGITAKPLHIASAGHSPLMDPVLDPLRRAAQKIAFRAP
AIPLVSNVTGDLWPWDQAPDAEHWCRHVRHTVRFSDGVRTLHDLGYRAFLEVGPAPTLLG
LVSDALPPDHDDLLLPSLRPKTDDWEVLLPTVAALYARGAGIDWAGFDRDYTRARTALPT
YPFDPTECWEPPRPWHRTDAPTEAPADAEAPRQEPTAAPARRRGRRRNSPIPTAEELLNL
AEAERLPTLTAQFVLGVQNVLGSASASAGVDEPLTGLGLDSLMAVELRNDIQNRLQVTLP
ITDFLGGATIRSVAEGVLERLASGDDAGPAEGTASAPSARTAPIRRRRRADDSAAADVLA
QLGDAVAGEEPPATQGEGRP
>A0A0N1GBL0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK006|TrEMBL
MPASESPKQFPEMSLTTSEDVTSEDVRAWLTSAVAEAAGLDPLAVDPERPIAEFGLGSRQ
LVTLAAELSGRIGRPVEPSLVFDHPTVAALAAAVLDDGPVGAAAPVPADAPVRGDEDIAV
ISMGCRYPGGADDPEALWRLLATGEDAITEVPAGRWDTRGLYDPDPEAPGKAYTLRGGFL
SDIDRFDAHFFGISPREAAAMDPQQRLLLRTAWETIERAGIVPDTLNGSSTGVYIGLYDS
GYQASAALGRLDGHVGTGSASSVASGRIAYTLGLQGPAVTVDTACSSSLVALHLAARALA
SGECDLALAGGATLLVTPRGHVEFSRLRGLSPSGRCSPFSTDADGVVWAEGCGLVLLKRL
ADARRDGDRVLAVVKGSAINQDGRSQGLSAPSGPAQERVVRAALDAAGLRPDDLDHVEAH
GTGTRLGDPIEGRALAAVFGPGRPADRPLGVGSLKSQIGHTQAAAGIGGVIKTVLALGHE
LLPASLHADTPTEHVDWAGGGLRVHSVARAWPRGGDRVRRAGVSAFGISGTNAHVVLEEA
PRDLVRPATGTPLADLPGATLFPLSARTLPALRGQAARLLEALDAQPRPTLPEVAATLAH
HRTHFEHRAVVRATDRDGLLTALRALAEGPTDTDSDTDTDTDTGTGTVVGPQQTVPTGKV
AFVFPGQGSQWTGMARDLLDRDPVFADELDRCDAALRPFTTWSVAAVLRGAEGAPPLDRV
DVVQPVLFAVMVSLAAVWRARGVRPDAVVGHSQGEVAAACVAGALSLNDAAAVVALRSQA
LTGLSGTGTMAVVALPHAEVENRLADLDGRVCVAAVNSGRSTVIAGDVEPLETLLADLDR
EQVFARRLDVDYASHSPGVEPVRATVLDELDGVTTCPTSVAWYSTVTGEPVTEELEADYW
YTNLREPVRFAPTVERMAADGYRCFVELGPHPSLVTALHTVAEDSGHENLVAVGSLRRDE
DGPACLDRATAELHVHGRRIDWRRLVPDTAPADLPTYAWDPRRHWIEPESTTGASGLFDR
AAHPLLGIQLQSPDETRWTFRGEWSEDTADWLPDHTVFGRTVVSGTTLMELCRAALAVAR
PDDPADLTDLLLLSPLTLPDSGTVEVSVEVVTAGPVPEITVHSRPRAQEATGWTLHATVS
ASAPAAPTADRPPVWPEAAEPAWTPETYERLTALGLGYGPAFQGVRSAVTTGDGELLARL
SLPPTARDAADPYPLHPALLDAALHVAAGLDASDGRVLLPVAVGRCVLPPGGARELTAAV
RRTGGSGTDLTLDVTLWDTDGFPAGRLEGVRLRAADPADLNGASENARHLYEVVWTAVPE
QPDEAPGTEWAVVGDPSDPEVAGALRGLAAAGTHVRSGTGGADVNGAGGVDVRGTGGVDV
FVRFWPRPATDAEPSAAAQELAAAALAELRALIALPQDEAPARTVWVTRGAVGAVDKDTV
PGLAQSVLWGLARSARAEHPELGLTLLDLDDSDPADALLTAATHAEEPELASRAGTLLAP
RLVRARDRDATGTPVGPDLVGRPALAPTDGTVLITGGLGAVGRHIARLLAEHGVPRLLLT
SRQGPDDPRAAEVAAELTGLGAEVEVAACDIADATAVAGLLGRIGEESPLRGVVHCAGVL
ADGVVAELTPERLAQVLRPKVDGAAHLHRLTVDARLDLFLLVSSAAGVVGNAGQGNYAAA
NVYLDQLAHHRRALGLPGVSLSFGAWAGEGLAAAHADLDRMARLGHRALTSDQGRELVEL
ALRQGAPHLVAWALDLPRLRETATTAATTGVGGTAAVWRSLLPAPRTGRSGGDGLADRLA
RLPEAERAERVLALVREEISRALGLRSTESVRPDQPLRELGMDSVTAVELRNRIGARIGA
KLPATLLFDHPTAARLAAHLLSTALAAGDRTTPATRPTRATTPAADEPVALVAMACRLPG
GVSDPEGLWNLVAEGRDAVGPFPAERWDVAALHDPDPDAVGKSYAHEGGFLNDDDLTSFD
AGFFGITPKEAAAMDPQQRLLMETAWEALERAGIVPAELAGSTTGVYVGMFGSDYLAGSR
LDQLDGYVGTGSALSVASGRLAYTLGLGGPALTVDTACSSSLVALHLAAQALRAGECDLA
LAGGVTVMVTPGTFVEFSRLRGLSPTGRCRSFSDDADGAIWAEGAGMVVLKRLSDARRDG
DEVLAVLRGTAVNQDGRSQGLSAPNGPAQEQVIRRALELSGLRPADIDYVEAHGTGTTLG
DPIEANALAEVFGDSRPQDHPLYLGSLKSNIGHAQAASGVLGLVKVVQSLRHRTLPRTLH
ADTPSRHVDWENSGLRLVRDTAPWPSSPGRTRRAGVSAFGISGTNAHVIVEEAPPVEKAD
VKDEVPPGKRLFVLSGRSGAALRGQAARLADHLTEEAGEDIALLDVAHTLARHRSHFERR
AALVAGDRDELLLRLDALAGGRPPPAAPRDDGTGKVAFVFAGHGGQWPGMGVELMAGSEA
FREELVRIDEAVRRRVGWSVLNALRAPEEFAPLGRTEFLQPVLFAVNASLAAAWRALGVR
PDAVVGHSLGEIAAAYSVGALTLDEAVTVVTGRGQAVVPLVGKGGMLSLELPPARVEELL
APFTGRLFVAAVNSARSTAVSGEADALAELRDRLDERGIAARPLTTPFASHTPLMDQLRA
ELLDRFSDVRGVRTPTPLYSAVLAEPVPGDRLDADHWYANLREPVRFADTIRRMLDDGYR
YFVELSPHPSLTSSIEAVAAEAGIDAVGIGSLRRQSDGHDVLLRGLGELYTAGHTPDWPL
LFPQGRRVDLPTYAFARERHWLAPAPASAGGSPLLGTHLEASDEPDRHLFQADIDLDDSR
FAYLTDHRVTGEVWLPGAAFLDMALEAASTLRGGGEVQLAGVRFVQPLPLEVNRPVRLQL
VLSPAEDGFRDFTIASTPSGGHGAPWQRHVSGRLAVTAQTAPDDEERLDAVRERCDEQVD
PAAVYAGLAALGIDYGPAFRGLEEGRRTNVAALGRLARTPAAGHLLHPAVLDAAFHTAAL
PGGAPEGRAFVPAAVGRLTFTGLRTAPVWATCRLRSVDGDTATVDLRLWDEDEQLILEAR
EFELAALSPLDGALFETRWQPCPAAQQPPAEGSWLILADDTGVAAELAERLGSTVPRVIA
RRGESFGVEGPGRYLLDPADPRHLARLLDEAFPDGPPERVVQLSALDAPAITDAGTAEEA
ARLCCLSTLHLVRALADRPGRAPRLFVPARGSQAAGDSTRVTHPQQALAWGFGLAVAQEY
PELSATLIDLPPTDGVDALWTQLRHADDERLVALRESGRLVPRLARTRPDDGGNGEVTSD
GVYLITGGLGGLGRVVAERLVRRGARRLALMSRGEPDGHTASWISGLEEHGTTVHLARAD
VADREELTAALDAVRREAGPIAGVVHAAGVLDDATVANLTDERVLRVLAPKVLGTTLLTE
LIPEAESLVLFASAAGLLGSAGQSPYAAANAFLDAWAHHLSRVDRRALSLDWGAWAGVGM
VAESGIRAAETGRSGLLALSPQDGGELFERVLATSRRQLAPLALDWETLAHDPDAARTRP
ILGDLITVPTGGDGADDLVASVFAATTARDRADRLEAYVRARVGQVSEGTVDVSATTALK
ELGLDSLMLVRLRNAFARELGAELPAATVFSASDIRGLARALGEVLPERDTAAQAGERRP
EARRPEAAVEVPESELRPATRDVLRLLRSARPGMPDAAHGVGLALRLTTPTTREALTDIL
TRLAGRHAALRTAIVTGAGGEHARLLRVDRELARPVLRWTDVPGDDELDGADRLRRLLEP
PFDLANPPLWRFELLDSGARGQVLAFGAHHAVSDLQSLLLVAGELDAELSGTSLGDAVTN
RDIDLLIEAQQTDDTPGEGVTAWREAFQGSDRLDLTLARPRPATRSYRAGSVSVTIPDGL
MERVSAAASGLAITPAAFCLGTLTVLLARMRQKERFVLAVPVDTRIHADAYDAVGFFGVP
VPFPAEAGAGERIEQVLRRTDGRLDRVLAKGAMFSDVLSTLARQGLHRANAPLVEVYFNY
VRSAADRLAHLEVLPAGTGYSDLDLMITMTPDAGRIRLDHNLDILDAATSVELGEEFLRL
LAEAADDPTAAVRSMPDTAVEATPAVRSTSGMAVEVPEGAPEDTRHSPRRSLALAATFAL
GNLPLLCEAAVGEGARDGGLTVAEAPYHQVLAALRDPSGVFADPTAAVGVALLRAADLER
FGPVDDALLAELRTAFPAALRAVSERTRKPLIVGFLPSAHARDRFARWEREIADELAEVP
GIAVLRPDDWTRRHAVEEPFDERTERIAHLPFTPHFQAAVALCLADVVRAVRRPAPKVIA
VDGDETLWGGVAGEIGPEAVDLTGPRALLARRLLQWRAAGALLALVSNNDEATVRAVLDR
PDSLLKAEHFSVLSATWGPKSARLAEAARTLGLGLDSFLFLDDNPVEIAGVRSALPEVLS
VTCPPSAELGEFLGRLWPLVPAAATAEDALRARFYEQERDRDAVRAQAGFEEFLAQLELE
VDIRALSGADVERAEQLVRRTNQFTLRGRSADGGDLGRWRECGEVWTAAARDRFGDYGQI
GLLALRADGDQLDVLAWLMSCRALGRGVEERLLRWLADRADELGCVKVRLTAERTARNVP
ARRLLAALGDGDQDDERLETVVTPEHLRAFRSWRRG
>A0A655A3M1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MSDAVAVVAARANVVGRLPGRYAVAALGIGEQDASALIATTGGWLELSVVNASSTVAVSG
ERQAVAAIVDTVRSSGHFARGITVGFPVHTSVLESLRDELCEQLPDSEFMEAPVQFIGGT
TGDVVAPGTTFGDYWYANLRHTVRFDRAVESAIRCGARAFIEISAHPALLFAIGQNCEGA
ANLPDGPAVLVGSARRGERFVDALSANIVSAAVADPGYPWGDLGGDPLDGDVDLSGFPNA
PMRAVPMWAHPEPLPPVSGLTIAVERWERMVPSTPVAGRHRHLAVLDLGAHRALAQTLCA
AIDSHPDTELSAARDAELILVIAPDFEHTDAVRAAGALADLVGAGLLDYPMHIGARCQSV
CLVTVGAEQVDAADAVPSAGQAALAAMHRSIGFEHPEQTFSHLDLPSWDLDPVLGVSVIT
AVLRGFGETALRGSVNGYTLFERTLADAPAVPNWSLDSGVLDDVVVTGGAGAIGMHYARY
LAEHGARRIVLLSRRAADQATVAMLRKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASL
IVHAAGSVISGTAPGVTSAAVVDNFAAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGH
GVVAYSAANRLLDVMAAQLRAQGRHCVAVKWGLWQAPKAGEPARGIADAVTIARVERSGL
RQMAPQQAIEASLHEFTVDPLVFAADAARLQMLLDSRQFERYEGPTDPNLTIVDAVRTQL
AAVLGIPQAGEVNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAK
LEDADERSHTAQKVDISRD
>A0A2Z5KDK1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. Go-475|TrEMBL
MGRDELIRPVADLLKEHAGAAPQRVAYADSSRSVTYGALERRTRGLAAYLVGTGLRRGDR
VAICLGNRVETVESCLAVLRAGMVGVPLDPRSSDAELAHFLQDSGAAFVITDAPRLARLR
RLGPPYDGLGVLVAGAGPVPADVQLLGSAAESGADVSGGSEGDGTESHATVGIDALGLDD
PAWMLYTSGTTHRPKGVLSTQRAALWSVAACYAPVFGLSSDDRLLWPLPLFHSFSHSLAI
LGVTAVGASARIAGELPAPGGLRRELLTAYEELGGPFTLLAGVPATYHGLVGSAGAAPPA
PRLCLVAGAPSGPALRAAVEETLGAPLLDAYGSTETCGMIAVNRPEGPRVDGSCGPPVPG
VEMRVVDPGSGADVPDGEEGEVWVRSPGLMTRYHGRPEATAAALRDGWYRTGDLGRRVEH
GHLRLTGRVGELIIRGGENIHPTEIEQALLRCPGVSDAVVVGEPHDVLGEVPVAFVVPGP
DGMDPRRVLAACRDLLADYKVPARIREITAVPRTASGKIARHALNAPARTASRTDGTGPT
APHEAASPTARTTPTAAHEATAPTARTTPTAPHEATAPTARTTPTAAHEATAPTARTTPT
ATHEATATTADTTPTAPHEAVVGTMSTTLRERLLSLSRDDRQRALRETVLAETAGVCRLA
PDEPPGPDSPFADLGMTSVGAVELVDRLTALTGLDLPSTLVFDHPTPEAVARYLGVALLE
ARPEDRPGPEGGQDGPAEDDPVVIVAMACRYPGDVESPEDLWELVSRGRDAISEFPADRG
WDLDALYDPDPDRIGTSYTRHGGFLHRAAEFDAGLFGISPREALATDPQQRLLLETSWEV
WERAGIDPASVRESDTGVFVGVMYGDYATRLTRPQELEAHLGLGSTGSVASGRLSYVYGL
RGPAITVDTACSSSLVALHWAARALRSGECSLALAGGVTVMATPKSFLAFSRQRGLSPDG
RCKSFSAAADGTAWGEGAGLVLLERLSDARRNGHPVLAVLRGSAVNSDGASNGLTAPHGP
AQRRLIRQALADAGLRPGDVDAVEAHGTGTTLGDPIEAQAVLATYGQGREEPLWLGSVKS
NLGHTQAAAGVAGVIKMVQAMRHGELPRTLHAESPTPHVDWSSGRVELLTAPRPWPASTR
PRRAGVSAFGIGGTNAHVILEEAPGAAVSPEPGDAAPGAAVSARPEHAAPEAAVSARPGD
AAPKAAGSARPGHAAPGTPGSARPEHAAPKAASSARPGHAAPGTPGSARPEHAAPKAAGS
ARPGHAAPGTAGSARPEHAAPKAAGSARPGHAAPGAAVSPEPASDRPAPWLLSAADETAL
RAQAGRLASAVARRPELLTADIGYSLAVSRGALAHRALVPSGDRTRMLEALRALAAGRSA
PGVVHGVADPEVRTAFLFTGQGSQRPRMGAELRAAFPVFAAAFDEACRHLDDRLPRPLGV
VLSAEPGSPEAALVDRTDFAQAGLFAFEVALFRLLESWGVRADRLVGHSVGELAAAHVAG
VLDLPDAATLVAARGRLMQALPEGGAMVALDATEEEVLSRLDESHMGESSPAESSSAEFG
FRVAIASVNGPRSVVISGADTAVRAVAAGFEAEGRRAVPLRVSHAFHSPLVEPMLDAFRR
VAEELDFRPPRIPVVSTVTGRPAQAADLCSPEYWARHARLPVRFADAVHRLAADGVSAFL
ELGPGPALTAAVADCLPGAATNGPVLAAATRGGAYEPETLLSAVARLHVAGAAVDRKAVY
ARPGARRVDLPTYAFQRQRYWLDEPLPAPDAPDAQPLLGPAFPVSDTGRTVLTGLLSRAA
HPWLADHVVAGRVIVPATVFVELAVRAGDEVGCDAVDDLVVLSPLALPGAAGVRVQVVVG
APDDSGRRPLDIYARPEESAEEVPWTRHVSGQLGRGRAAEDEPVPWPPEGAEAVDLSGAY
AALADAGLAYGPAFQGAGAVWRRGDDVFAEVRLPAPHAAQAGRFGLHPALFDAASHAPLL
AAPADASAIRVPFAWSGVRLYASGATEVRVRATRTGADTVSLTLTDPAGRLVARVDSLTT
RELPAERAGLAKDVVRGSLLRPEWTAIELSGGVDDRRAWAVRGPDELGLAAFLPGAGEPE
FVAVTAVARATAPDPPAAVHELTGRVLATLQDLQDDPGAAGSRLVVVTRDATAPVPDLAG
AAVWGLVRTAQSELPGRVVLVDVDGRPESLRLLPAAVATGEPQLRLRDGRVTVPALAAVH
EVADAGAAFGADGTVLITGGTGALGAELARHLVTAHDVRHLLLTARRGPRAPGAEELRAE
LAESGARVGIVACDAADRAALAEVVRRAEPPLTAVVHAAGVLDDGVLDSLTPARMAAVLR
PKADAAWHLHELTRDSGLSAFVVFSSVSGLLGRAGQGNYAAANSFLDALALRRAAEGLPA
LSLAWGPWEHTGGMAAGQPPMRPRSRDVLMPLSTRQGLALFDAAVRTSEPVLVPVLLDRA
ALRSPGGPLPPPLRGIVRPNRPAAAATATATAMASGSPGGAGRTPEPGAWRARLDRLPVS
DRRAALTELLRADVADVLGYPHADALPPGRSLAELGFDSLTAVQLRNRLSTALGLRLPVG
VVFDHRTAEDLARHLLGLLPTEPTAAATEPTASPTEPTAARTATATAAREETGPITAAAR
EKTGPITAAAREVTDPTTATTREAVPATAGPGSRPAHTLSSLFRNVRAAGQPVAAMHLLV
TASWALPTFPAARGHEHALPPIRRSPARPGSGRPGPGRPAIVYFPAYHPSLPSDGGDFPR
FHRALGDDLDVLEFPHPGIGAGTAVPENLAALAHTQAGAVLRHVGDGPFVIVGRSAGGNV
AHLVAHRLEGMGRAASGLVLLDTYHVTPDNSGTDWLVSLAAPPPRGTGQPDVAGDDDSTL
AAVGAYNRIFLGWTPEPVTTPTLLVRALRPTPAMADSADGDGWRTSWPTAHDVVDVPGDH
LTMMREHAGSTASAIRAWIEARARPTLALPIESR
>Q0RTS4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia alni (strain ACN14a)|TrEMBL
MLSGPPRLRASRRLIPHMANEAKLRDYLNRVAADLHQTRQQLREQEAARREPIAIVGMSC
RFPGGVSSPADLWRVVDEGLDVTGPFPTNRGWDVDGLYDADPDRPGRTYARSGGFLHDAP
EFDAAFFGISPREALATDPQQRLLLETAWEAVEEAGIDPVSLRGSATGVFAGVIAQEYTP
RLHQPTPERVDGYVLTGSTTSVASGRVAYALGLEGPAVTVDTACSSSLVAIHLAAQALRG
GECTLALAGGVTVMSSPGMFVEFSRQRGLAPDGRCKPFAAAADGTAWAEGVGVLVLERLS
DAQRLGHRIHAVIRGSAVNSDGTSSQLTAPNGPSQQRVIRAALAAAALTPADVDAVEAHG
TGTTLGDPIEAQAILATYGTDRPADRPLRLGSLKSNIGHSQAAAGVGGIIKLIGAMSHGR
LPKTLHVDAPTPHVDWSAGTVTLLTEPADWPTTPDRPRRAAVSAFGISGTNAHLILEQGP
IPADAGTADGDTATGGTGTDGTGTGGTGTGGTGIEDAAGADTADGAGDAGRGPAVRGRAL
PWVLSARTAEALGGQATRLGAFVDAHPGLAPVDVGRALATTRAALEHRAVVVAEDPAGFR
AGLAALAAGSGGSAGSAGVAGVEVIAGIATPDGAATDARIVRGVADTTATTVFVFPGAGT
AWPAMARELLATSPVFAEHINAVAAALAPYVDWNLLDVLRERPGAPTLDRVDVSQPAVFA
VLVALARLWQHHGVHPHAVVGHSQGEIAAAHIAGALTLDDAARVVALRGQILGALPAPGA
VVWVNLPADQVRERLARFREGAAAVSVAVLNSPTSTAVAGTEEPLAEFVAGLQAEGIRTR
DVPVGYASHSARVEAVREELLAALAPIRPQPATIPILSTVTADWIDPTALTADYWYTNLR
QPVLFEAATRALLDDGHDLFIEVSPHPVLTTALAETLENTPGLPGPVAITETLRRDTGGL
TRFHTSLAQAYVRGAGLDAAAVYAGSGRGHVDLPTYAFARRRFWLDASSTSPSGDAAGLG
LGSADHPLLGATVRLADSDGAVLTGLLSLRTHPWLADHVVFGSVVLPGTALVELAVRAGD
ETGVPVVEELIVETPLVLPERGGLQVQLTVGAPDEDGLRPVSIHTRAEDASAQAAWTRHA
HGVLRAPEATDAAVSSGVPSGASPEVWPPAGAVRVDTGDLYPSFAAAGLVYGPTFQGLRA
AWRDGEDLLAEVTLPADALDRAGAFGLHPALLDAALHLTGLPSAATALDGTVLNGTAPSG
TAPSGTAGGTRLPFVWRGVRLHASGAGGLRVRLRVSGPDQIALTAVDGTGAPVVSVAGLA
LRPVTAEQIRSAPGPRNDSLFALTWPELPATPGGNSSGAVEPPGAVEVVTDLDELAARID
AGSAVPNLVAVAAPAPPGEATEPDAVAARARTAAADTLALLQRWLTEPRWAEATLAVLTS
GAVSVAGEDVDLTTAPLWGLVRTAQNEHPDRILLIDLDADPDSRTALPAAVATAQATGDN
QLALRRGTAHTPRLVPATTPTAPPTAAPGAAHPADPAKPADQTDPADPADPAGWNLDPDG
TILITGGLGTLAHHLAHHLITHHHTRHLHLTSRTGPHHPHATALRTELENLGATITITAT
DTTNPTQLHHLLDTLDPHHPLTAVIHTAGTLDDTTLTNLTPERLHTVLAPKIDGAWHLHH
LTRHHPLKAFVLYSSIAGITGNPGQANYATANTFLDALAHHRRAHGLPATSLAWGLWDDT
STLTENLTAADRARLGAGGLRPLSPADGLALFDAAGTLDEPLLVPAALDLAAIRAQSAQR
GVPPLLRTLVPPVRRAAGAGIGVTAPGGSSLARRLAELTPGDRPAEALAAVRREIAAVLG
HATVDGIAADRAFSALGLDSLTAVELRNRLNTATGLRLPATLTFDHPTPDALAAHLVTTL
AADDARPTGTGNSTGITSATPAATDEPIAIVGMACRLPGGVTTPEELWELVAEGRDAISA
FPTDRGWDLERLYDPDPDAAGTSYTRHGGFLHDAADFDAEFFGITPREALATDPQQRLLL
ETSWEAIERAGIDPTTLRGSTTGVFAGVMYHDYGTRLREVPPELEGYLGTGIAGSVASGR
ISYTFGFEGPSVTIDTACSSSLVALHLAAQALRSGEADLALAGGVAVMATPTEFIEFSRQ
RGLARDGRCKAFAAAADGVGWAEGATMLLVERLSDAQRHGHPVLAVVRGSAVNQDGASNG
LTAPNGPAQQRVIRAALAAAGLGPADVDAVEGHGTGTPLGDPIEAQAIVATYGRERPADR
PLWLGSLKSNIGHTQAAAGAAGIIKTVLALHHGLLPRTLHVDAPSPHVDWADGAVALLAE
PTPWPDTDRPRRAAVSSFGISGTNAHVILEQPPTAANAPAVGPAPAEAADPQTAAGDPAA
PADGPQGDGGAVEALPVLVPLSARSPEALRDQARRLATHLRTHTTDHTTGADGADDADDA
GAGAGAGATSNAARVPLPALARALATRTAFPHRAVTLATSTPELLTGLDRLADGQPTPAV
ITGQAGTGKLAFTFSGQGSQYPRMGHTLYATHPIYRQALHDTADALNPHLDQPLLDILHA
DPDSPEATTIHHTAWTQPTLFALQTALYHLITSHGITPDYLIGHSLGEITAAHLAGILTL
DDAARLVTTRAHLLASLPPGGGMLTLHTDEPTTRTLITHHPSIDIAALNSPTNTVIAGDT
PTLTHIAEQAALQGIRSRTLTVSHAFHSPLTNPILTPFHTTAATLTYHQPTIPIIAGLTG
TLPTDSDHTTADYWTRHIRHTVRYTHGTTTLSEQGVTTYLELGPDTTLTTLTTQTLTTLD
RSGHRPRFTATPTLHRTKPPTTTLATALATLQAAGHTPTPPSISSISGATADSTSPGSDG
DSTTGEDATASSTDVARLAAALPTYPFQRQRYWLEDTASAGSDRQASPLDAADTGFWDAV
QHADATTLADALGISDPTDQNALATVLPALNSWWARRVTESQADSWRYRIVWRPVPESTG
APAAADGDWLLVVAPEFVDHPRVAVAARALEGAGATVRRLVVPATADRHTLAAELTRLLA
ADGPAVAGVLSLLALDESAHPQAAATPVGIAGTVALLQALDDSGLDARLWIATGGAVSTS
AADPVTRPADALLWGLGSISAVERPGRWGGVVDLPEQVDGQVDEEVELLLATALRAGHGE
TELALRRGGLLARRLVPAPATPKTTAPKTTAPETTATDTTATATTEPGSVAGWAPGGTVL
ITGGTGALGGHVARWLAREGAAHLLLTSRRGERAPGAADLAAQLRALGARVTIAAVDVGD
RAALAEVISGIPVELPLRAVVHTAAVLDDGLVSELTLEQIDRVLRVKVGGALNLHELTRD
ADLAAFVLFSSIAGTAGITGQGNYAPGNAFLDAFAAHRRAAGLVATSIAWGQWEGAGLAE
PDVDRILRRHGLLAMDPQPAVRALARALAGDETHLAIVAADWRAFYRSRPHPLVHELPEV
AAERSASAERSGRPVGATGGGDGPVLGARLAELDGPARREALLAIVRDHVAAVQGHASPD
AVDVDRGFRDQGFDSLAAVNLRNRLIAETGLSLPVSLVFDYPTAATLTDHLLAELVPAEP
AEPAGLPAVLAEIDRLESALADVADVDREAAADRLRDLLTRLGGPAADGAAVAAELSAAS
DAELIDFIGKTLGIS
>A0A086JT50|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii p89|TrEMBL
MMTRLPLCQQQAPPSLAGCHMLAAFQDIPERPLNRDLKELWAAYGENPFGNVLECWNRSI
PDEDAVVWLNSDGEISETTTFSELFSRITRLSSFLRAAGLQVGDRIILCYPPGTDFVTAF
FACITSGFVAVPVYPPDPSKGLSDVPRFCDINEIAGCKTALTNSLYKRVVQVITTVAKDS
RWRSVHWVCTDDVIKRHAEEAKNSVGPDFPNLSPHHPAFLQFTSGSTGNPKGVIVTHGSL
LHNCHLCWSAYQFPSHYENDGDDENITNHDFALVNQREFWRRRQEISIKSRGHRLRAFSW
LPVYHDMGLIGFVCSPILCGATLYQMSPIDFIRRPWLWLQGMSKYDCICCAAPNFAFEVV
TRKMPDNVYEHLDLSRVCGFLSGAEPIRASTIDRFCEKFGPKGVRRCAVCPAYGLAESTL
IVTARKTFQTVPKLLIVDSFQLQHEKTVVALKPEATVTMDSEEYQVLVGCGVPLEGVQVR
IVDPETKKELPPGKVGEIVVYSSSVARGYFGRPDTTKETFCYSFTDLQGKQTPPLGMRTG
DGGFMYEGELFVAARLKDLIIIRGRNFYPQDIEEAVDKVAMVRPGSSAAFAIEVDGHEAL
AVAAEVRLEEGIKGLWLRVKRQFDRSHYEQIVRDISKSVAANTGLTIHRIWLLRPRTIPK
TSSGKVRRSLTKEKLVSGKLEGILLDHAHHQHQAFYHDGPGGSRSRTRTGSGATPSGGAA
TRDGTASSNPSGDAHPKNSNTSNSITDSSHSVQRGSLRGDACVAGGRLGPSASHGGVHHE
KDHKHRGDGSGMSSPDQVPGAGAAASESSAHVALTEKVKQTVFEAAKTVLGSSEIPEIDA
PLHELGVDSIGAVEFSELISAELQVDVEPTLLFNYPTLSDVIDFFVRELEGKGSEDLAVS
LEKTGARETTTAIIGAACNLPGGTTSLNAFWDLLMCGVDAIAEVPRSRWDVEEYFDPDPG
ADGKAYVREGGFIEDAEMFDAAFFRISPSEAKSMDPQQRLLLEVAYESLYDSGYTREGLQ
RASVGVFVGCCSNDWYQVCSQLELGISSYTTTSYAPSIIANRLSYTFGLLGPSMTIDTAC
SSSLVALHIAAQELQGGSCMSAVVAGVNLMLSPHITVAFCKSRMLAPDARCKTFDASANG
YVRGEGLGSIVMKRLSQAEKDDDRILCILRGTAVNHGGRSASLTAPSGPSQQRVIRTALR
QAELTPGDIYFVETHGTGTSLGDPIEVGALKSVFGASRDAKTKPLILGAAKTNIGHLEGA
AGIAGVLKAMLALRYKHIPPNLHFKQMNPHIDVREFNVVVPTAPMAFPREDGGRLFAGVS
SFGFGGANGHVILQEALQQPSGDKPPCKRHSKRSIICFMFTGEGYEVSCMGRHLYETDDV
FKEIITKCNDILKRWLNVSLLSILYPPADKKMEMDKMMCQARFGHTALFAFEYALAESMV
SKGVKPDVVFGVGLGELVAAAFSGVMSLEEALYVVTQRAKLIDNLPPFEGVMVACRVSEQ
EVEMALSEMEINSRQSISIAAVYGRKNLILSGEQSEIDNVLMKLNIAGRWKYLPVHNVLT
MNLVSDIIPPFTHLMSTVKLCRPKVRLVSSTTGEFVDKEALSGRFWSRQVSQTVQLQQAV
GNIVASGCSLFVEIGPQVVLTKLAQQSLNGNAKDVTWVPAYDTTSDDVRVFENAVMTCNE
AIKIIGKERSLEEGQHGQEELIFHRKPFPWTEIPHPFLSGHKFTEKDDVVFENAFPRRAI
PLIADHAVNGTAMMPGAGMLEMVGAAALALDLRTTSGAVSLENISFERPMLIGAHRVTYE
YNRRHSLGEGGGAGTSPRTVRTPRLVNHAYTRLGFREKSAEKAISETAGPASTEGGRTPV
AGHHHGSYTKAGVLEDIKDYAHNVLRRAAQHAEEIDVHTPVPPSMAPPSIVARHPREGSY
GSMSRTSGIMGSNDRGDGLTVPLSVEMAIRCRVTKMKEVELSTVWDDEVTDHCFATIVIA
DKKQETYSSLQEVRCRCTERMDVNEYYDMLYDAGLQYGPRFRTIQELYRGEKEALARVHF
VGNVKQDPFESGFLIHPAVLDGALQAAGCLLEQSHSGNKVMVPVSVGSATLTKVEVFQPC
WAHVRLEETKSKAATLNVTIYDEVTREVVASLQNAVLRQVDPSASVVATIPKDLLWKVNW
QLVVEGDKEVVGRTPKVLFIGGNIELSEALENAMGSTCKTLSVDALPREKAELQKVLDAE
QWQAIVYVEAVTAGVYDALDVMNAAVRLVQAHYLNLNSGKAVGALWFVTRDTVFRDNGAD
KPGVEIPAHAGLWGLAKAARLEMEVSAGSPISMGCLDVSGADVSSMAQQILHALKSKVLT
MRETEVAVREDGLYVSRLAPQTEVDVRGAIEFHMPERGAISNLVLRPQAFASRLPPEDGQ
IELRVRAVGLNFRDVLNVMGLYPGDPGPPGADCAGVVVAVGDNVEHIEVGDCVFGVAQGC
LRTYVTTDSQLLRRMPESMTFEQAAALPVVATTVEYALHDLAKVKAGDKVLIHAVTGGVG
LVAVQLCKRVGATVYGTCSGGKKDAFAKSMGVQYVSSSRDAKAFAEDMRTFLGEDGKVDV
VLNCLIDDFIPESLKLLGPYGRFMELGKRGVWSKEKVAAERPDVQYELIAVDEMMEKDPI
WFGGMLVRVRGLVAEQKIQPLPMHVFDLADTGENGGVAAFRFMQRAQHMGKVVLKIPSPV
EEASKNGSIVITGGLGALGMVVAGWLAEEGARHICLLSRREEAPQPGEIPGWDWLRTINC
DVQFFSCDVSKYDSIRSVLRTIQTSVAPITGIIHTAGALADALLDSQTPELMKKVYNGKV
QGAWNLNRALEELGLNEQLKLCVFFSSVTSLFGNFGQANYCSANACLDALAQWRRAKGLC
CQSIQWGPWIEQGMAAELKQQVERNGMKGISNEVGLRVLHDAIRQQEKATPVIGCQAIKW
KLFMHRYIEQPPFFTNIEMDLQVTSHDSNTVLRNLPPSERRDYIKAQVAAAARQVLGSSS
PPPFDTPLQDVGVDSLGAVEFRNVLSKKLGVKLSATTLFDYPTLNAIIDHLCEVFGESSQ
KDNLSTKLGALSENDLVQEGMAIVSMSCRLPGNSTCPDLFWDMLMRCTDCVCDIPLTRWN
AEEVYSEDPDLPGKCYTRRGAFIENAEYFDNSFFGISPSEVKHMDPQQRLLLEVAYEAFA
GAGLTKEKLLGANIGVFVGACNHDWTYLIQEDKISAYTGTGSAGSVIANRVSYCLGLRGP
SVPVDTACSSSLVAADFAFEKLMLRDCTMALVTGVNLMLTPHLFIAFSKARMLSPDCKCK
TFDASADGYVRGEGAGAVLMLPYADAKAKQMTIQAVVKGTACNHVGRSASLTAPNGPSQA
EVIRMALRRAGMKPNDLKFMESHGTGTSLGDPIEVNAVRTVFAPGREKTKPLLIGAVKTN
IGHLEGSSGIAGLIKACLVLSRREIPPNLHFKTLNPHINIEDFPVQFVTDFVSLDSVEST
RKKNTAGVSSFGFGGVNAHVLLEEATRDQNATRKEENRPKICFMFTGQGSQYVGMGRHLY
EKEPVFREAITRCVEIAKEYLPLPLLSVIYPSPDERDKMQEAINETLYSQPAVFVISYAL
LELWKSRGVEPDMVMGHSLGEYIAAVCSGVISIQDGLKLVLKRAQIMSRAPSRNGVMVAC
RATAEQVEEAIHTLFGDGEKNVALASVNGLKSVIVSGNQQDVQAVLRQLGAASRAKMLRV
SHAFHSPLVKDTVAPFKRVLETVRLSKPRVMFVSTVTGKVARDELQNTNYWAEHITKVVR
FCDAVQACIAQGAKIMVEVGPRPTLSNMGKGCLPQTTADEVQWINSLEPETLSSAVFDSL
SALAKAGSGAMPAVFDRKFFPWTETCHPLLGGKNTRPDGSVVYSALLRDLVKALFLDHVV
YGKALLPATCLIEMMASATTHMISNHDEEKLVALSQVVFEKPLLVPDETSLSVLVTVETR
GQVRVASQVSNSEEEAEDHAVCQVNIVDALPAAPALTEIRARCKTEIEASQLYAQLHNVG
LQYGPRFQTIVKVFKGEDEVLGLLQAQNVTNFETGFMMHPAVLDGALQLSAVLAFEKGSS
RAMVPFGVDTVLLKSCPPDKELWARVVMNRKGVSSASATVHLYDFDGEPIAVLMGVTLRP
IEFNTAADIPRELLWEVEWESAGSYSMPQDGSLATPSGTDDSGAEDVTRTPSPLVTGENE
NTPSREVPSALPGLSTETPRASKPLSTDETSGAVLNKSVHSVLLVDYAGGHREVVASIRD
TCDVEVEVLSKPGSPELYAQQLRQFAEVVATKTETVPLSTILFLALDEATPAEQLAGGLL
ETVKVFAVEKFKKLPCIWVLTSGAQGPTRSVVSPKHAGLWGLMRTVRLELEMQIGKMVRF
GCVDLDKNLEVSVALHFILQKRTEEPFEAEMILRCPSEDSEKEPGTAEVVNRRERSASFV
SVGPEPVVPSTTDASAKSSVTSDRMALTPGALSCFDETANSTEKLIFNAFCPRLHRSPIP
VRGAVELHMPERGAISNLVLRPQAFASRTAPQSHECEIRVRAIGLNFRDVLNVMGLYPGD
PGPPGADCAGTVVAVGSGVRHLKVGDSVYGIAQGCLRTYVTTNGNLMRRMPESLTFEQSA
ALPVVAATVEYALHDLAKVKEGDKVLIHAVTGGVGLAALQFCKRVGATVYGTCSGGKKAA
YAKSLGVKYLTSSRDASAFAEDMREFLGEEEKIDVVLNSLIDNFIPESVKLLAPGGRFME
LGKRGIWTKAQMAAERPDVYYETIAVDTMMQEDTVWFGGMLDRIRDHVDSGNIPPLPLHV
FEMTDPLAGGVAAFRFMQRAQHIGKVVIRIASDLEVKIPSTTEPAATETAMLAEAGTQGN
ASIGTSTQQIADRT
>A0A378TP32|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium tokaiense|TrEMBL
MGENISVDEGGVVVVTGGARGVTARSALALAQRHGLQLALLGRTALREQPAGLRTQGTTL
TEIATALVASARERGQQMGLPEARSQAAALLAEQEVRDTLAGAEQQGTTARYFAVDIADR
AELGRVLDQVRQDLGPIVGVVHGAGVLADRRLEDLDEAQFTRVFATKVMGAEALLSATAT
DHLRFISLFSSIAARAGNPGQSAYAAANAALETIAARESVSRGCDCVVRAFGWGPWDGGM
VDATLKSRFLSSGVDVIPLEEGAQFFADHALRRSPATAIVVAAPAQPRLRTARLDWDVST
EILPMLVDHQVRGRVVVPVVMVVDAMLRAAEGLLAGERCVVQDFQVLSGVTFADREKQEL
TLDFEPAGPAYTVTVTDGEGRKRYRAAVVPEDSAVPRLFVPETSGADWPMSVAQAYTDRL
FHGPRFAALDQLGTVGPGGGTATVKGLHELGWPQHNWAIDAAAVDGGLQLGILWSGVHGR
PLVLPVRIGRAVLHRPVDAASALRCRLAAYPVSDKQVDFDIVLESGDGQLVAELAAVEFY
VAGSGADSSA
>A0A378TLI4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium tokaiense|TrEMBL
MSFPDGRVPVVLSAHAADLVRADAAAVLGHLGDRPDVDVAAVAAHLLRTRRIRRYRAVIR
AADRAELIAGLTAVAAGEDHPLVTHSGVAAAPRLAFVLPGQGNQWPGMGADAYRLLSDYR
ATAEVFEAAFAAAGHDTPGPYLRGDAREFTQIQIQAAQFVHAVALAAVWRGCGVTPDLTV
GHSLGEVAAAYLAGALTADAAVGVVAARAAVVGELPGEYGMAVLGVDADTARALIDGNPG
WLELSVVNADSSVVVSGERSAVAELVRDAERSGRFARHIDVDFPAHTSALEPLRGTLQAR
LPRAEFTDSAVQFIGSATGAVVLPGTDFADYWYTNLRNTVRFDRALHTALRCGATAFVEL
SAHPALLFALSDLVDSAPELPEGPAVLVGSGHRDRPLVDELSANIAAAATVDPGYRWIDL
LPPAHSPALRDFPPAPMRAGFFWAAPQPMSPVPTVSVLTETWAPAPPARAGDRRIGVLDL
GGGDTIAESIRAAAADAVPVADADLVLVLAPRDTGADVTRAAADLAARVDAGLLDYVEAL
GAGCRDVWLVTAGGVCAREGDPTPAPVPAALAVMHRSLGHEAADHTFHHLDLPGWDTDAT
TLLDAVRSAHGEVALRDGGLLRRDVTQNPPDAAPPLPADQLDNVVITGGSGTIALHFARR
LVERGARRVVLLSRRGADAPAVREFLRTCPAGVEVHAPACDITDRQSVAAAAEAYADGGA
SLVIHAAGTAAFAPRLLVSGEHLQQMCAAKLTGLTNLVDLWPLHPDARMLLCSSVIGVWG
GKSATGYAAANRLLDVLAAQLRTQGYRCASVRWGLWQGSNIIDAAEINRVERSGLQQMAA
RPAVEAGLRDHAGDPLILSADPDRLRTFLDTAEPEAGAIAVDSPAHAADAVRAELVSVLN
LADRPLDPAATLFDLGMDSLLALDLRKRITRVTGRSVALATLLGGITVRELVATFEESDS
PT
>A0A2K8RL39|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MTRTDPSQAAIAVIGYSCRLPGAPDPDAFWRLLLDGRHAITEAPADRWTAAQLDAAGTPH
AAGARWGGFIEHPDAFDAAFFGVSPREAAAMDPQQRLALELSWEAVEHAGLLPAALAGTR
TGVFIGAGWDDYATLRRQSAGEITHHTLAGTQRALIANRLSHTLGVRGPSQLVDTGQSSS
LVAVHLACQSLRSGESVTALAGGVSLNLALDTALVAAGVGALSPTGRCHTFDARADGYVR
GEGGGLVLLKPLDQAVADGDTVHGVLLGSAVNHDGDGSALTVPDATAQREVVALAHRAAG
VSPADVDYVELHGTGTKVGDPVEAAALGASIGGARPAGSPLLVGSAKTNVGHLESAAGVV
GLLKTVLAVRHGSIPASLNFDTPSSDIPLDELNLQVVTGHGSWRGDRRVAGVSSFGLGGT
NCHVVVAAHLPDGSAAPASPERAAVPGAVPLVVSGRTPAALRAQAARLADWVDGHPGTDP
VDLGGSLLSSRTLFDHRAVSLGADGLRALATGGAGDNAVTGHATAAVGRTVFVFPGQGSQ
WVGMARELMDGSPVFAARMDECGQALEPFTNWRLADVLGDADALERTEVVQPVLWAVMVS
LAAMWQSLGVVPDAVLGHSQGEVAAAVVAGALSLEDGARVVALRARTLRALAGRGGMTSL
ALSAREARALIGPGLSVATVNGPSSVVVAGAPEALAELEALAGERDVRARRLPVQYASHC
AQVEEIEERVLDVLRDVTPRAGSVPLFSTVNVDWADGTELDAGYWYRNLRRTVEFEAAVR
TLADAGYGVFVEVSAHPVLTAAVAETAGDVITGGTLRRDDGGWERLKRSAAELFVQGVDV
DWSPLLSGAVRVALPTYPFQRQSYWFDRVAEPAPAVTAVEDTGLPALTELVRSHAAAVLG
HPSADGVDVSLAFKALGLDSTSALELRGRLAAATGLRLPAALVYNHPTVEEVASFLHRSL
HGAGTAAPALAPTAAPVDEPVAIVAMSCRLPGGVRSPEDLWRLVESGADAVGPLPEDRGW
DLDALLGDEGDGTSHTGFGGFLDGVGDFDADFFGISPREALAMDPQQRLLLETSWEAFER
AGIVPATLRSSATGVFVGAMSQDYLPRLHEIPAEVEGYGLVGGAGSVASGRISYTFGLHG
PAVTVDTACSSSLVALHMAARALRGGECSLALAAGATVMAGPGMLMEFSRQNGLARDGRC
RSFSDDATGTGWGEGVAVLLLERLSDARRNGHPVLALVRGSAVNQDGASNGLTAPHGPSQ
ESVIRDALADAGLTAAEVDAVEAHGTGTVLGDPIEAEALLATYGQDRERPLWLGSLKSNI
GHTQAAAGIAGVIKTVAALRHATLPATLHVRTPSSRVDWSAGAVRLLTERTEWPAAGRPR
RAGVSSFGVSGTNAHIVLEEAPQAAPAADGHTPDAAPASAPWILTARDAHALRRQAGRLA
EHLAAAPQPRPLDVGYSLAAERTAFEERAVLLAGPAGLRALAEATPGDGLPLPGVVRGTA
LPGARTVFVFPGQGSQWAGMALELARSAPVFAERLRACEDALAPYVDWSLSEVLAEPGAP
GLERVDVVQPALFAVMVSLAALWRSHGVHPDLVVGHSQGEIAAAVVAGALSLEHGARVVA
LRSQALRALAGRGGMVSVAEPEEAAVRRLTRWGDRLSVAAVNGPGAVVVSGDPEALDELL
AMCEEEGCRARRVPVDYASHSAYVEEIREAVTEALDGIEPRRATVPFLSTVTGEVLEGTG
LDAGYWYRNLRGTVRFGPAVEDVLSAGSALFIEVSPHPVLMQGISESLDHTSERPAAVLC
TLRRGDGGPERFLNSLAEAYAHGAPVDWTALYEGSGARRTELPTYSFERRRYWLDTSRAA
APARPGPGTWRYRVTWTPRPDADQAPAPDALAGRWLAVVPEHLAEDAYTAEVRAVPAAYG
ADVRTVTVAADADRAVLAERLRDAAGDGPVAGVLSLLALDERPCPGHSAAPTGLVSSVAL
VQALGDTGLTAPLWLVTRGAVAVDATDRLTAAEQSPVWGLGRVVGLEHADRWGGLVDLPA
GLDEDTRTRLAAVLAGLPAGGAADPARGTEDQTAVRAAGVSVRRLTRATRGARPRARTWE
PRGTTLVTGGTGALGAHVARRLADRGADHLLLVGRGGPQAPGADALRQELEERGSRVTIA
ACDVADRDALAALLATVPREHPLTAVVHTAAVLDDDMVAALRPEQIDRVLRPKLVGARHL
HELTRTLDLDAFVLFSSVAATFGVPGQGNYAPGNAFMDALAEQRRAEGLVATSVAFGPWA
GAGMAGRDGVGGLLARHGLPAMDPEDALTAMERAVADDETCLTVADIDWDRFFLAFTASR
VRPLLYDVPEVRRIRAAAATAAEEPGTAGTALARRLAEAGEEERGRILLDVVRSHIAAVL
GHSGAEAVPVERTFKELGFDSLTGVEVRNRLAAATGLHLPATVVYDHPTPAALVRHLRAE
LAGSTGAAPGPDPAPVPAGADGDPIAVVAMSCRFPGGVRTPEDLWRLVDESTDAVGAFPA
DRGWDLDGLYHPDPAHPGTTYVREGAFLDDAAGFDADFFGISPREALAMDPQQRVLLETS
WELLERAGLDPTTLRGSRTAVFAGTNGQDYPALLAAAPADHADSEGYGSTGAAASVVSGR
ISYALGLEGPAVTVDTACSSALVALHLACQSLRRGECDLAMAGGVTVMSTPGLFLSFSRQ
RGIAADGRAKAYAASADGTAWGEGAGLLLLERLSDARRNGHQVLALVRGSAVNQDGASNG
LAAPNGPSQQRVITAALADAGLRPDEVDAVEGHGTGTRLGDPIEAQALIATYGRDRDADR
PLWLGSVKSNIGHTQAAAGVAGVIKMIMAMRHGLLPESLHLDAPSDVVDWIGGAVQPLAE
ARPWQPRTGAPRRFGVSAFGISGTNAHALLEEPGRQDAEHAAERTGDRPATGARLFPLAA
KGRTALRAQAANLLAFLESGTVAEEALTDVAYSLATTRAALPDRAVVLAEDRDALVRALG
ALAEGRTSAGIFEGTARDEAAQSVAFLFTGQGSQHPGMGAGLYARVPAFAAAYDEVCAEL
DRHLERPLRRVVEEDAEVLERTEYAQPALFALEVALFRTLREWGVHPQRLAGHSVGELAA
AHAAGVLTLADAAVLVTARGRLMQAQRADGAMLAVQASADEAAGPLAEYGDRIAVAAVNA
PGSVVLSGDADAIAALEGHWRQQGRRTKLLRTSHAFHSAHLDGMLAEYERIAAGLSYAVP
RIPVVSTVTGAELTPEEACSPAYWARQARATVLFADAVRTLRAVGTTTFVELGPDGVLSG
MVPDCLPEESPLAVSLLRAGRPEEQTLLAALARLHTAGAGPDWEALFAPAGAVRHALPTY
PFQHKRFWPHVPAAPGAAGQAADRWRYRIGWTEPVRPATPGAPDHTWLALVPDTDAAGTA
SAVCLAWLRELGTSVVPVAAGTGRDALAQLLRDAAGPGPVSGVLSLLALDERPHPDHPAV
PAGLAGTLTAAQALTDAALGAPLWLVTQSAVTVDQDRDTARPEQAQTWGLGQVLGLEQPE
LWGGLVDLPADVDATALARLGAAVTGGGDEDQLAVRAEGVRARRLEHAPAPEAGPLWQPR
GTVLITGGTGALGRHVALRLAQDGAEHLVLTSRRGPAAPGADALHDELTALGARVTVEAC
DMTDREAVAALLAAHPPAAVVHTAGALGLGSIAEDSVATLGEIAAAKVLGARHLDELLGD
TPLDAFVLFSSIAGLWGSGGQGAYAAANAHLDALAARRRARGLTAVSVAWGPWAGGGMAD
DEALDRLRRRGLAALAPAAAVAALRALAAGPDATVAVADVRWEDFAPAYTAARPRRLVED
LPEVRAVLAGRAEDPEPPASAFAAHLVGLPAARREEAVRDLVRDHVAAVLGHDRADDIAV
DRVFRDLGFDSLTAVELRNRLVEATGVRLPVTEVFDHPTVADLAGRLYAGLDATAPGAED
RTATAHTARTTGEPLAIVAMACRFPGGVTSPEDLWKLVADGEDAIGALPAERGWDLERLY
HPDPDHEGTCYARGGGFLHDAGDFDAAFFGIAPREALAMDPQQRLLLETSWEALERAGID
PTSLRGTQGGVFVGAAMQGYGSGSIDGAEGHLLSGTVTSVASGRIAYTLGTEGPAVTVET
ACSSSLVALHLAGQSLRSGECAYALVGGAAVMASPDVFVEFSRQRGLSADGRCRSFAEEA
DGTGWSEGVGVLVVERLSDARRNGHPVLAVVRGSAVNQDGSSNGLTAPNGLAQQRVIRQA
LANAGLEPADVQLVEAHGTGTTLGDPIEAQALLATYGQDREEPLWLGSLKSNIGHTQAAA
GVAAIIKTVMAMRHGTLPRTLHAEQPSTKVDWSAGHVRLLTEARPWEGPRRAGVSAFGMS
GTNAHVVLEQPEPQPDETPAPADPDRTAPLLLSARTAGALRAQAAGLHRLLRDTDVPTAD
VARTLAGRARFGRRLAVLGADRDALLSALAAPDTAPNAVTGEADSGRTVFVFPGQGTQWT
GMALELADAEPEFAARLDACAQALAAHTDWSLREVLADETALNRVDVVQPALFAVMVSLA
ALWRSYGVHPDAVVGHSQGEIAAAVVAGVLSLDDGAKVVALRSRAIRHSLAGKGGMVSVA
ADESTVRGLLDGHAGRIGVAALNGPAATVVSGDPEALDALVADCDTRGVRARRVPVDYAS
HSAHVEEVREELLAELAGVRPAQGDVPLLSTVTADFVDGTTMDAEYWYRNLRETVALHAA
TERLLRTGHTLFVEAGPHPVLVAGIEGTAADAGLPVTTVGTLQRGQGGRERMLAALAEAW
VAGADVDRTALTGPGRRAELPTYPFQRERYWLPTPGRSAAGAPQQASDVLYRTEWRALPD
QDISGTLDDWAVVVPDGGHPLTAALPGVVTTDADLKGVTGPVGGVLSLLAPADTPALVRA
LDTAGVQAPLWCVTTEAERDPEQAALWGLGQVIGLEQPQRWGGLVDLPVGLDDTVVRRLR
TVLAGTENQVRVRADGTYARRLVRTPQVAPPAERWAPGRALVRGAHEPLAADIVGWLERH
GAEGVRVSDDPAARPEPDERTVIQVAPAEPPAGPVTEAMLSMLSVPAEPDGDMDTFVLLH
PLSGVWGAARQATGTARYAGLAALTARLRDRGVRAVSVAVGGWEPQAPAETPVPADTVMA
AVRRAVERDEPALIVADVDWDLIVSAVSTPRQLNLISELPEAAAEEHGDDLVQRLSALPE
ADQRRALLDLVTEQIGAALGHAAPGAVRPDSPFADLGFDSLLAVQFRNRLCTATGLAISP
TVVFDHPTPAVLADHLLGELLAEPDPVAPMLAELDRLDRALSQLPVADEISIRLHTLLRH
WDERSAPAEAGELSSASADELFDLLDNNFGSA
>A0A5B7ULN5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MNDDKLRDYLKRVAADLHRTKQRLGEAEARDREPIAVVAMGCRYPGGVRTPEDLWRLVST
GTDAITPFPADRGWDLAALHDPTGERPGSTYSAEGGFLDDAAAFDPGFFGISPREALAMD
PQQRLLLETTWETFERAGIDPHALRGSRTGVFAGVMYQDYAVRLRQVPDDVQGYLGNGSS
DSVASGRVAYTFGLEGPAVSVDTACSSSLVALHLACQALRQGDCALALAGGAMVMSTPVP
FVEMSRQNGLAADGRCKSFAAAADGTGWGEGVGMLLLERLSDARRHGHPVLALVRGSAVN
QDGASSRLTAPNGPSQQRVIRQALANARLTPADVDVVEAHGTGTPLGDPIEAQALLATYG
REHTAAQPLLLGSLKSNIGHTQAAAGVGGVIKMILAMRHGEVPPSLHGGDLTPQVDWSPG
TLRLVTEATPWPATGRPRRAAVSSFGVSGTNGHVVLEQAEPTAEPTAGPTAGPTAGPAAE
DDRTGPVPWLVSARDPRALRAQAAALHAHLTRHPALHPADVAHTLATGRAALEERAALVA
DDRPALLDALDALARDTDPLPPGCARGTARTGEAVAFVFPGQGTQWPGMARELLDTSTVF
AARLAECAEALAPHTDWSLLDVLREAPDAPSLDRVDVVQPALFAVMVSLAQVWRAHGVEP
AAVVGHSQGEMAAACVAGALTLADAAKVVAVRAKALRALAGRGGMASVSLPADRVRERVA
PWGERIAVAAVNGPSSVAVSGDPGALAELLAALDADGVRARPIPVDYASHGPQVEEIQDE
LTQALAGIAPRAADVPFYSTVTGGLLDTARLDASYWYENLRRTVRFDEAARALLTDGHRV
LVEVSAHPVLTAGLQDTADATGTDALALGTLRRDDGGPRRLLTALAELHVRGVSVDWDAA
LAGHRPHRVDLPTYAFQRERYWLEDSGAPAGDPASVGLTPSGHPLLGAVVTLADTEGLLL
TGRLSLRTHPWLADHAVRGTALLPGTAFLELAVLAGDHTGCPRVDDLTLEAPLTLPQDGG
AVLRLSVGAPAPDGTRTLALHARPDDPDTDEEWTRHATGVLAPRTPAPAPAAPTAWPPPG
ATPLDLDGMYARYAAGGFAYGPAFQGLTAAWRLGDDLYAEAELPAGLRQDAARFALHPAL
LDAALHATGLTAAAADGGRMPFAWSGAALHASGATALRVRLTVTGTDTLALDVTDTAGSP
VASVECLTLRPAAPAPGTGRAHHDALFRVEWTPVARPRAGTDTTPVAVGPHSFGLTHPHP
DLPAFLAALDTGAPAPGTVLLAELPGGEGGTGSADTGAARHALHRTLAALQTWLTDERLA
GTRLAVVTRGAVAAAPGEAPADPARAAVWGLVRSAQSEHPGRFVLLDLDADADTEALLSA
LAADEPQLALRGGALLAPRLGKVPADAPAPVALDPDGTVLVTGGTGLLGSRVARHLVAHH
GVRHLLLAGRSGPDAPGAAEAVTELVALGAQVTVAACDAADRAALAALLDGVPADHPLTA
VVHAAGALDDGVVTSLTPDRVDAVLRPKADAALHLHELTQDLDLKAFVVFSSAAGTFGGP
GQGNYAAANAYVDALAQWRHARGLPAQSLAWTLWEQRSALTGHLDDADVRRLARSGMPAL
TTEQGLALFDAALTVDAPALVPLRLDRRALRARAAEGEPVPPLLRALVRVPVRRAAAAAP
TADTGTSLAERLAPLPEAEQRRTLVQLVCAQAAAVLGHTSGDAVAPARAFRDLGFDSLAS
VELRNRLGAATGLRLPATLVFDHPSPEALAGLLRDELAGTATGASAPVPVASAADEPVAI
VAMGCRFPGSVRTPDDLWRLVASGADGIGDFPTDRGWDLDALYDPDPGHTGTSYVREGGF
LTGAGDFDADFFGISPREAIAMDPQQRLLLTITWEAFERAGIDPAALRGTPTGVFVGLMQ
QDYAVRLLPHIPEDVEGFLGTGNSGSVVSGRVAYAFGLEGPALTIDTACSSSLVALHTAV
QSLRRGECALALAGGVTVMSSPELFVEFSRQGGLAADGRCKSFAAAADGTSFGEGAGILV
LERLSDARRNGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRAALADAGLSAKDVDA
VEAHGTGTRLGDPIEAQALLATYGQERLEGRPLWLGSLKSNIGHTSAAAGVAGVMKMVLA
MRHGLLPQTLHVDAPTPQVDWSTGDVRLLDEARAWETGGGPRRAGVSSFGVSGTNAHVIV
EEVPQESVVAGACGVGGPVAWVVSARSPQGVRAQAERLLEVCGEEDVRISDVALSLVETR
ALHEHRAVVAGGREQLLAGLRALAVGEPSGCVVSGGGLVCGGTVFVFPGQGAQWVGMARG
LLDESAVFAGLMGECGAALEPYVGWSLVEVVRSGVGFERVDVVQPVLFAVMVSLARLWRV
FGVVVDAVVGHSQGEIAAAVVAGGLSLEDGARVVALRSRAIVRIAGSGGMVSLALSSAEV
EERLAGWGGRLSVAAVNGPSAVVVSGDSDALGELVAGCEAEGVRARRIDVDYASHSAHVE
RIETELLEALKGIAPSSSEVPLFSTVTGEWLDTSVMDGGYWYANLRRTVAFEPAIRALAE
QGFGAYVEVSPHPVLTVAVEATLESAESTAVVLGTLRRDEGGLERMLLALGQAHVHGLSV
DWAPLFEGTDATRVELPTYPFQERRLWLDVPTTSWDVASAGLGTTGHPLLGAAVEIADTG
ELLCTGRLSRRTHPWLAEHAVQGVALLPGTALLELALRAAAEAGCATVDELTLGAPLVLP
EEGAVLVQVRLGAPDPDGRRALDLYSRAEREAEREAEGGQPSWTPHASGTVAPAGRPAGP
ALIAWPPPGAQAVDVEDLYERFAAAGYAYGPTFQGIRAAWARDGEVCAELVLDERQHADA
PAYAVHPALLDAALQTAALLPGRDDTARLPFSWSDVTARDPGATAVRVRLTADGPDAVAL
AVYDLAGQEVLSAGSLALRPLAAGGLRRAGQDRDGLHRVEWVPAPDADVTLGEGSWVRLA
DLRADPDAAVPAVVVADCPWPDGAEDPGDEVAPLHAATAHGLALVQEWLADARFADATLA
VVTRGAVRTAPGDRAAALAQSGVWGLLRTAQTEHPGRFVLVDLDGLPESRAALPTVLAGA
EPQTAVRHGEALVPRLTAGPGRDTLVPPAGSEAAWTVGLAGDGAVDSLAAVPAPAALAPL
GAGQVRIAVRAAGLNFHDVVVSLGLDPDQAVLGSEGAGVVLEVGADVADLAPGDRVLGVF
GGSFGPTAVADRRTLARVPAGWTFAQAASVPIVFLTAYYGLFGLGGLREGQSVLVHAAAG
GVGMAAVQLARHAGAEVYGTASPAKWDVLRGSGLDDAHIASTRTPDFAERFLDASGGRGV
DVVLDCLAREFVDASLRLLPRGGRFVEMGKTDVRDADEVARDHPGVRYRAFDLMEAGAER
VGAMLAEVLSLFERGVLTPLPVTCWDLRQAPQAFRHLSQARHIGKNVLTLPAPLDPDGTV
LITGGTGTLGGRVARHLVTAHGVRHLLLAGRRGMAAHGAGDLVRDLTDAGAEVTVAACDV
GDRAALAALLAEVPDAHPLTGVVHAAGALDDATVAALTPERLDRVLAPKADAALALHELT
RDHDLAAFVLFSSGAALLGGAGQANYAAANAALDALAAARRAAGLPAVSVAWGMWRERSA
LTAHLSDADVRKMARGGVGALTTDAALALFDAALTAAQPHVLAAAVDTAALRVAAAAGSS
LPPLLGGLLPTARRAPAPRPAAAPAGPSLAAQLADLAPAEAHRVLLDLVRGHAAAVLGHA
STELIGGERPFKDLGFDSLTGVELRNRLASGTGTRLPAALVFDHPTPEALARHLAERLLA
DTGGPAGGSPGTAELDRLDALVGELAAAGPDGERRRTDLARRLRGALARLEPAAADGTER
EGPDAADAIESATNEEIFDLIDKELGIS
>A0A5B7ULL6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MENEDKLRDYLKRATTDLRSARRRLREVEERDSEPIAIIGMSCRYPGGVESPEDLWRLLA
DDGDAVVEFPADRGWDVEALYDPDPDHAGTSITRHGGFLQGATGFDPAFFGISPREALAM
DPQQRLLLETSWEAFERAGIDPEQARDTRTGVFAGVMYNDYAARLPQAPEGFEGFLANGS
AGSIASGRIAYTLGLVGPAVTVDTACSSSLVALHLAMVALRREECSLALAGGATFMSTPR
TFVDFSRQRGLARDGRCKAFSDSADGTGWGEGVGMLLVERLSDARRNGHPVLAVVRGSAV
NQDGASHGLTAPNGPSQQAVITQALANARLTPEQVDAVEAHGTGTTLGDPIEAQALIATY
GQDRPDDRPLWLGSLKSNIGHAQAAAGVGGIIKMVLAMRHGVLPRTLHIDEPSSHVDWSA
GTVALLTERQPWPEAGEPRRAGVSSFGVSGTNAHVILEEPPAAEPVPPAADLPAAPVVPW
ALSGRTPDALRAQAQRLLSTVTGAAGFDPVGVGFSLATTRTAFEHRAVVLAEDPTTTTDR
LTALAEGRGAPGVVVGEAEPHRLGFLFSGQGSQRLGMGRELAQQFPVFAEALDAVLGEFD
ASVREVLFGEDAEALNQTGVTQPALFAVEVALFRLLESWGVRPDVLAGHSIGELAAAHVS
GVWSLADAAKVVSARAGLMQALPAGGAMVAIQATEEEVAADLPETVGIAAVNGPSSVVIS
GVAAAAEAVGERWRAAGRKVTRLKVSHAFHSPLMDPMLDEFRRVLESVSYEAPAIPIVST
LTGARASAEELASPEYWVRHVRESVRFHGAVTALREQGVDVFLEVGPGGVLSGLGQSAAP
EAAFVPALRGDRPELVALTTAVGQLHVRGAAVDLAACFDGSGARRVDLPTYAFQREHYWL
DAPAADEAVERMSPAEAKFWEAVEEGDPADLAWTLGVSSDDPLSAVLPRLSAWRSKQRNR
STADAWRYRIDWRPVAAGPRRLDGTWLVVAPAGESRAEWVGDALTRNGAAAHVLYVDPAA
ADWAERLGGAPAPDGVVSLLGLAAADGPTVPAGVAATIGLLRALGDADVPAPLWCVTSGA
VAAADSDEVAGFAQSTLWGLGRVAALEHPGRWGGLIDLPEARDETTGDLLASALTGTTGE
DQLAVRGGQLLGRRLLPAPLGDAPGDGWSPRGTVLVTGGTGALGGRVARWLAERGAEHLV
LVSRRGAAAEGAAELEAELVGLGARVTIAACDAADRDAVAALLERVPSLTAVVHTAGVEH
PAALADLDPDDLTAFADVLAAKADSARILHELLADEPLDAFVLFSSIAGVWGSGGQAAYG
AANAYLDALAAHRRAAGLPATAVAWGPWGGGGMVADSGQAGHLRRAGLAIMAPDAALAGL
GTALDHGEGQITIADVDWARFADTFTAQRPSPLLRELPQARAVFDAAPAEHEGTSALARR
LAGLTEAEQERQLTELVRYEAATVLGHVSGDAFSPTRAFRELGFDSLTAVELRARLGEAT
GLALPASVVFDYPTAAALAAHLRTELSGAAPAAAAPLAVSGATDEPIAIVAMACRFPGGV
SSPEGLWDALLAGEDAVTEFPADRGWDLEGLYAPDPDTAGVGTSYSRRGAFLDRVADFDA
DFFGISPREALAMDPQQRLLLETSWEAFERAGIDPNALRGSRSGVFVGTNGQDYTTLMMA
APETVEGYLGTGSAASVISGRLSYTFGFEGPAVTVDTACSSSLVALHLAVQALRSGECEL
ALAGGVTVMSTPAAFVEFSRQRGLSVDGRCKAFSDGADGTGWGEGVGMLVVERLSDAQRN
GHQVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLSPSDVDAVEAHGTGTKL
GDPIEAQALLATYGQDRPAGQPLLLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGVLPRTL
HVDEPSSHVDWSAGAVELLTGERAWPVVDRPWRAGVSSFGFSGTNAHTVIEQAPVAEHEE
ASESLSEGAVVPWVLSAKSPVALREQAARLKSFVEASAELSAADVGRALVFSRAALEHRA
VVVGADSPELLAALEAVAEGRAGGAVATGVADEPGRVGFLFSGQGSQRLGMGRELAERFP
VFAEALDGVLGEFDASVREVLFGEDVEALNQTGVTQPALFAVEVALFRLLESWGVRPDML
AGHSIGELAAAHVSGVWSLADAVKVVSARAGLMQALPAGGAMVAIQATEEEVAAHLPETV
GVAAVNGPSSVVISGVAADVEVVAEQWRAEGRKVTRLRVSHAFHSPLMDPMLDGFRQVLE
AVSFGEPEIPLVSTLTGARASAEDLASPEYWVRHVRESVRFADAVGTLAGEGVGTFVEVG
PGGTLSALGDGSAPDAVFLPALRADRPEETALVTTVGALHARGVTVDWSAFFAGSGAPLV
DLPTYAFQRERFWLDVLPSVGDVSAAGLGAAEHPLLGASVALAGTDGVLLTGRLSVQSHP
WLGDHEVMGSVVLPGSAFVELAVRAGDQVGCDLVEELTLEVPLVLPEGGSVRVQVSVGAQ
DASGAREVTFYSSTGEVEEASSWTRHAVGVLREGGRSAGPALVAWPPAGAEAVDVDGFYD
RVADPDFAYGPVFRGLRAVWRKGDEVFAEVVLPEGVDAGGFGLHPALLDAALHAIGLMGE
ADGAGRLPFSWSGVRLHAAGATVLRVRLAPAGADGVSLAVADGAGAPVATVDSLVLRPVS
LDQFAGDDRGDSLFGVDWAPVALMLDGDVPTTEWSDLEALAGPRDGELPDFVVLSCPVDS
VSGPVVGAREAACWALNVVQRWLVDERLAAVRLVLVTRGAVSTVPDEGVGDLAQAAVWGL
VRSAQSENPDRIVLVDLDDEAASLEVLPSVLATGEPQFAVRSGEARAPRLVRAAQSAVDD
PGFGTGTVLVTGATGTLGGLVARHLVAERGVGSLLLVSRRGAAAEGAEELRNELTAQGAE
VMFAACDVADRDAVAALLAGHQVSAVVHTAGVLDDGVIASLTPERIDAVFRPKADAAWHL
HELTSGLELSAFVLFSSASGVFGTPGQANYAAANAFLDALAEHRRAQGLPATSLAWGLWD
TADGMAGSLDENDVRRITSGGALPIGPTEGLALFDTAGSTGRATVAPMPLDIPALRRQAR
TQPVPHLLRGLVRGTARRTAAPAAARSALAQSLAGLTAAERDNALLDLVLGHVAAVLGHS
SAQAIAPERAFKELGFDSLSSVELRNHLNAATELALPSTLVFDFPTPAALAAHLRAELLG
GALDVTVGGPVAATTDDPIAIVAMSCRFPGGVESPEDLWRLVTEGGDAVSEFPTDRGWDV
EALYDPDPDAVGTTYLRSGAFLSDVSGFDAGFFGISPREALAMDPQQRLLLETSWELLER
AGVDSASLRGERVGVFVGSNAQDYGLVVGGAAEDVGGYMATGNAASVASGRLSYTFGFEG
PAVTVDTACSSSLVALHLAVQALRSGECELALAGGVTVMSTPGAFIEFSRQRGLAQDGRC
KAFSDSADGTSWGEGVGMLLVERLSDAQRNGHQVLAVVRGSAVNQDGASNGLTAPNGPSQ
QRVIRQALASAGLSPSDVDAVEAHGTGTKLGDPIEAQALLATYGQDRPEGQPLLLGSIKS
NIGHTQAAAGVAGVIKMVMAMRHGVLPRTLHVDEPSSHVDWSTGAVELLTGERAWPVVDR
PWRAGVSSFGFSGTNAHTVIEQAPVQATEQGPATEPAYEGLVPWVLSAGDEAALRGQAQR
LLSVVDEHAPVDVGYSLATSRSALERRAVVVGADRSELLAALTAVAEGQASGAVVTGAGD
ASGRVGFLFSGQGSQRLGMGRELAERFPVFAAALDGVLGEFDASVREVLFGDDVEALNQT
GVTQPALFAVEVALFRLLESWGVRPDVLAGHSIGELAAAHVSGVWSLADAAKVVSARAGL
MQALPSGGAMVAIQAAEEEVASDLPETVGIAAVNGPSSVVISGVAADAEAVGERWRAAGR
KVTRLTVSHAFHSPLMDPMLDDFRTVLEGVSYEAPAIPIVSTLTGARASAEELASPEYWV
RHVRESVRFADAVSALAGEGAGTFVEVGPGGTLSALGQESAPDAAFVPVLRSDRPEEAAL
VTTVGALHARGVAVDWSAYFAGSGARRVDLPTYAFQHQRYWLDARPSAGEAVLDEDEARF
WAAVDSEEATALASSLGITDDGVSDSLRTVLPLLSSWRRQSREKSAVDKWRYTVGWQALG
HPATTPPSGPWLVVTPQDDGRADALGELLEACGLALVTVTTGATDRAELADALRAALTRG
EAREEISGVLSLLAFDESAHPGHPAVPNGVAATLALVRALGDADVSAPLWCVTSGAVSAV
ADDTVTGFGQSMVWGLGRTVALEHPGRWGGLVDLPETVDDRAAARLCGLLGGAEDQVAVR
EAGVFARRLRRAERAAAGSGWTPGGTVLVTGGLGALGTRAARWLAANGAEHVVLASRRGE
SAEGAAEVRAELVELGARVTVAAVDIADRDGLAALLDGLAAAGDPVRAVVHTAGLNDSVP
AAETDLAGFADVVTAKVAGAAHLHELLADTPLDAFLSYSSIAGTWGSGGQVAYSAANAYL
DALAEHRTAHGLPGTAVAWGPWAGGGMADGEAQRQLSRRGLQALPPELAVGAVADVVGSG
TASTVVANVDWERFAPAFTIGRPSPLLDGVAEARAAVADRPAGPQEQDEEGAELRRSLTG
LDAAKQRDLVRALVVAQAAAVLGHASAGAVEPDRAFRELGFDSLTAVELRNRLTVASGLA
LPATVVFDYPSPAALAEHLLTEVVEPHGGPHPARDTVVAGKTDEPIAIVSMACRFPGGVT
SPEDLWDVLLAGGDAVTDFPADRGWDLEALYDPDPEGVGTTYSRRGAFLDRVAEFDAGFF
GISPREALAMDPQQRLLLETSWEVIERAGIDPNTIRGERVGVFVGSNVQDYGMVLDGAAE
DVGGHVATGSAASVMSGRLSYNFGFEGPAVTVDTACSSSLVALHLAVQALRSGECELALA
GGVTVMSTPAAFVEFSRQRGLSVDGRCKAFSDGADGTGWGEGVGMLVVERLSDAQRNGHE
VLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLSPSDVDAVEAHGTGTKLGDP
IEAQALLATYGQDRPAGQPLLLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGVLPRTLHVD
EPSSHVDWSAGAVELLTGERAWPVVGRPWRAGVSSFGFSGTNAHAVIEQAPEATSVDDAE
PVAHGVVPWVLSARSGEALREQAKRLRERLDQEPDVSVADVAHSLRARSTFDHRAVLVGL
DRQEFLSGLSALADGREAPNVVTGVAEDRGSGVVFVFPGHGSQWVGMALELLDSSPVFRA
RMEECARALEERVDWSLLAAIRDPELMERLDVVQPALFAVMVSLAAAWRSWGVEPSAVLG
HSQGEIAAACVAGALSLEDAARLAVVRSKALTVLAGHGGMVSVALGVDAVRELLEPWEGR
LAVGVVNGPASVVVSGDADALDELVRDCAGKGVWARRVLADYAPHSHHVERVEADLLAGL
ADVAPRSADVPYFSPLTGGWLDTRDLDAAYWYRSLRQTVEFADSVSALVAEGFTTFVEAS
PHPVLAAGLGELAGPDGVVVGSLRRGDGGPARLLASASGLFVRGGRVDWELPGARRVDLP
TYPFQRERFWPTASHAASGDVTSAGLGHVDHPVLVAVTELADSEGLVFSGRLSLRTHPWL
ADYRVLGAALLPGAAYVDLALRAGDHVGCASLDDLVLEAPLVLPERDGVQVRLSLDGPDA
SGRRAFTVDSRGDGGGDWTRHATGALAAGAEPVTDDLVAWPPSEAEPVDLDDHRATVAAA
SGVDHGPAFQGLHTAWRKGDEVFAEVTLPDGVAADGYGLHPALLDGALHAVGLGVSAHGL
PFSWAGARLLATGATTLRVRLTPVGVDAVAVLVADGTGEPVAAVDELSLRPLSADQLNLA
RSAHRDSLFEVKWVPVPDAAPEGGTWAVLGGDTARPAHALTAAGEPVDEYGDLAELIAAV
DTGVPVPRCVAVTPGEGATTPREATGRTLGLLQQWLADDRFAESRLVLLTSGAVAAGPDE
DVPDLVRAPVWGLVRAAQSEHPARFVLVDVDEHERSLTRLPAAVATGEPQIAVRNGTATV
ARLARLAVPADAPEPAAFASDGAVLITGGLGVLGGVTARHLVTRHGVRDLVLTGRRGAAT
PGAQELRRELAELGARVAVVACDVSDRAAVAALLAEHPVTAVVHTAGVLDDGVIGSLTPE
HVDTVLRPKADAAHHLHELTLGTDLTAFVLFSAVAGVFGGPGQGNYAAANAYLDALAQHR
RAAGLPATSLAWGLWAEASGITGHLDDADVQRMARGGMVPLSSEDGMALFDAARASGAAT
AVPAAIDLAALRAHPERVGPMLRGLVPTPARRAARSGSGSGTVPLAQRLAGLTEAEQDRA
LVHLVRTHTAAVLGFAGPDAVEADRAFKELGFDSLTGVELRNRLDAEVDARLPATLVFDH
PNPAALAAHLRTTVLADGGTAAAGVLSELNKLSVTISKLDADDELAGDIRLRLRSLLSTW
DDKEPEAEADDLTSATLDDVFDIIDEELGKS
>A0A3N6FMG4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI97-07|TrEMBL
MHVVDSVFVMPGTVAAPRAGVLSELHHRYETVREALSRIDKAAGEMGLPPISARLIERDG
TNDGRGPEVQYLEIFAVSIATHHMLIAEGVKPVAIVGQSIGELWALAAGGHLSVEDAARL
AVARSQVLTRQNWDGKMLAVGVDGRRAESLAGLMNHPDLVLACENAPRQSVISGPERLIE
QVERVADAFGWPSLPLDVPHPTHTPAMAQAARDLRATAPRVPYGSGRWRVCSPWLGRDIG
DDDPVDLVAGALTARVRMLHTIRELHAAGADAFVECGEWPVVTKFVEASIPGVQCVVPLS
EGDPVEAVRALLAESADVGRFRSRPSPASTGHGPAVRVSAPAPVRAASVSAPPAPAPSAG
VATTPASYTAPVTYAAPAAPAQEAAVVVAAAAPAAVAPAVPPVSAGLDYDSVLTELRTLY
GDFLGYPADLLGEDDGLESELGVESLKQVVLLGRVSDRFDLPDLRANSSLLTVGTLRRIA
ETVVQARAEAAAR
>B8MBM6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MRAGMGSTSWAYVFGDQTSEFDSGLRRLLQAKGNTFVTSFLERCSFALRHEVTQLPPSDR
RKFPRFTSITSLLSRYRESGPNPALESALTIIYQLGSFISYYGDGGQIYPVGSESYVIGL
CTGLLASAAIASSRTIGELIPLAVEAVVVALRLGLCAYKVRNYVGQYDGRSQSWSAVISG
VSEERALALITEFGKKKGLSPSSRPYVSAVSYNGLTISAPPLVLEELIDSELSKHAKPLR
VAVHAPFHAPHLYGQEDVEWALNTTNHGSFKDYCSRIPVLSSTTGYEIAAESFEDLLRVA
VEEILLKQLCWDKVLDGYSSIIKGSSVSTCTIFPVATSASSGLVSALKRAGISEVLLENT
LSDSTKPGKFPSTTGRTEQSKIAIIGLSGRFPDAPSPEHFWDILYQGLDVHREVPPDRWN
WKTHVDLTGKKRNTSQVPYGCWIPEPGLFDPRFFNMSPREALQADPGQRLALVTAYEALE
MAGFVPDSTPSTQKDRVGIFYGITSDDYREINSGQDIDTYFIPGGNRAFTPGRINYHFKF
SGPSVSVDTACSSSLAAIHMACNALWRNDCDAAIAGGTNILTNPDNHAGLDRGHFLSRTG
NCNTFDDAADGYCRADGVGTVVLKRLEDAIADNDPIQAVIAGAYTNHSAEAVSMTRPHVG
AQAFIFDKLLNEADVHPNDVSYIEMHGTGTQAGDAVEMKSVLDTFAPDHGRKPEQTLHLG
SAKSNIGHGESASGVASLIKVLLMMRKSTIPPHCGIKTKINQNFPTDLKERNVHIAFKPT
PWVKPESGLRRCFLNNFSAAGGNTALLLEDAPNRQIATIADPRSMFSVAVSARCQASLKN
NIKNLSDWIEKHSSDMKEDEFLAKLSYTTTARRIHHPFRIMVSGTKVSEVQEALRAAASR
ETISTAPSVASGAGFVFTGQGAQYTNMGKQLFEGFLQFRSDVLRFNGIAQSQGFPSFVSL
IDGSVPIEEFGPVITQLGTTCMQMAIANLWISWDVRPTFVMGHSLGEYAALYVSGALTAF
DAIYLCGRRAQLLEEKCKVGTHAMLAVRSGLSEITPFLNPGVHEVACINAPGETVISATS
QNIDALAEQLVAAGIKATKLKVPFAFHSSQVEPILEELTKVTKGVKYHKPSIPLVSPLLG
EVINEKNYEQLSGTYLSRHCRETVNFLAAIEASRHAKLMTDKTVWIEIGSHTVCSGMIKS
TLGPQANTVASLRRNEDTWKVLSQSLTSLYIAGIDIQWKEYYQDFKSSHEVLHLPAYSWD
NKNYWIDYKNDFCLTKGGDPVPQITSPAPSHLTISAQKIVKSIGEANKATVITETDISDP
RLCPVIQGHKVNGTPLCPSSLYADIAQTLAEYLIVNFKPELKGVGLDVADMAVPKPLIYK
NAGPQLFRAAATADWDGRQVSMQIYSVTPEGKKMADHASCIVKFFDVEAAQEEWKRNAYL
IHRSVDRLFQNVANGDSNKLGCGMVYKLFGALVDYDKNYKSMRDVILDSDQYEATALVKF
QAEKANFHRNPFWIDSIGHITGFTMNANDATDSANFVYVNHGWDSMRCATKFSADATYRT
YVRMQPWQGTIYSGDVYVFEENEIIAVYGGVKFQGVPRKILNTVLPPPGGTAQVTKPATK
GPVPVPVTVPKTKPIAKAVKCSAPKTPAPSVLVQAFKILASEVGLSEAELSDDLVFSDYG
VDSLLALTITGKFREELNLDLESSIFMDYPTVKDFKGLLMQSATPVDSSESSSESSVFDD
SGLTEPPTPGTPGDYPPPMKVAPSLEEDKTLATIRQTLIEEIGVSAEELTGEANLSEMGM
DSLLSLTVLGRLREALGLDLPSEFFIENPTMGQVGEALDLKPKAPIRQPKSAMLSTSAPL
LQPEDLSSKLQHPPATSILLQGNPKTAKHTLFLFPDGSGSSTSYATLPKISADVCVYGLN
CPYMKTPEKLNCALQDLTASYVAEMRRRQPKGPYNVGGWSAGGISAYDAVRQLVIEQGET
VERIFFLDSPFPIGLEKLPPRLYKFFDDMKIFGDGKAPPPKWLLPHFLAFIDALDMYEAV
PFPSNDPKYESRLPKAYLVWAKDGVCGKPSDPRPAPSEDGSHDPREMLWLLNDRTDFGPN
GWDTLVGKHKVASIEALHEANHFTMMDGSKAGGLSSFIKNAF
>A0A376LLT0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Escherichia coli|TrEMBL
MAAISTKIAAGVLRGIVQTRQPRQPLRILEVGGGTGGTTAWLLPELNDVPALEYHFTDIS
ALFTRRAQQKFADYDFVKYSELDLEKEAQSQGFQAQSYDLIVAANVIHATRHIGRTLDNL
RTLLKPGGRLLMREITQPMRLFDFVFGPLVLPLQDLDAREGELFLTTAQWQQQCRHAGFS
KVAWLPQDGSPNAGMSEHIILATLPGQAVSAVTFTAPSEPVLGQALTDNGDYLADWSDCA
GQPEQFNARWQEAWRLLSQRHGDALPVEPPPVAAPEWLGKVRLSWQNEAFSRGQMRVEAR
HPAGEWLPLSPAAPLPAPQTHYQWRWTPLNVASIDHPLTFSFSAGTLARSDELAQYGIIH
DPHASSRLMIVEESEDTLALAEKVIAALTASAAGLIVVTRRAWRVEENEALSASHHALWA
LLRVAANEQPERLLAAIDLAENTPWETLHQGLSAVSLSQRWLAARGDTLWLPSLSPNTGC
AAELPANVFTGDSRWHLVTGAFGGLGRLAVNWLREKGARRIALLAPRVDESWLRDVEGGQ
TRVCRCDVGDAGQLATVLDDLAANGGIAGAIHAAGVLADAPLQELDDHQLAAVFAVKAQA
ASQLLQTLRNHDGRYLILYSSAAATLGAPGQSAHALACGYLDGLAQQFSTLDALKTLSVA
WGAWGESGRAATPEMLATLASRGMGALSDAEGCWHLEQAVMRGAPWRLAMRVFTDKMPPL
QQALFNISATEKAATPVIPPADDNAF
>G0Q9U2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MANSEKTLRDYLKWVTADLHETRQRLRDAEDAAHEPIAIVGMACRFPGGVSSPEDLWRMV
EDGVDAVSHLPTDRGWDVEGLYDPDPDAPGKTYVRDGGFLYDASRFDAGLFGISPREALA
MDPQQRLLLETSWEVFERAGLDPTGVRGRRIGTFIGGNRPDYAAHLGTVPDGVEGHLLTG
SNSSVTSGRIAYTFGLEGPAVTLDTACSSSLVALHLACLALRHGDCGMALAGGSAVLSTP
EGFVAFSRQRGLSKDGRCKAFGAGADGLGLAEGIGVLLLERLSEARRNGHRVLAVIRGSA
VNQDGASNGLSAPNGPAQQRVIRAALGDARLTTADVDLVEAHGTGTPLGDPIEAHALMAT
YGQGRPTGRPLHLTSYKSNIGHAQAAAGVAGVIKTVMALRHGVLPRTLHAEEPSPHIDWT
AGDVSLLTESRPWPETGEPRRAGVSSFGISGTNAHIILEEAETAGAEAEAAADAAPDRDA
TAATTTPEGAAAAGQTSPEQPRAAAAQTAAPAVVPWTVAARTADGLRAQAGRLLAHLREH
PELAPADVAAALATTRAALEQRAVVVADDRAELLAGLEAVASGAAAAGTVTGTGAVADRA
VFVFPGQGAQWARMGLELAADFPEFDRALGDCAEALAPFVDWDLRAELAGDLARVDIVQP
ASWAIMVSLARLWRSFGVTPAAVVGHSQGEIAAAVVAGALSLEDGARVVAERSRVIGQRL
AGRGGMASVALPATTVREQIDGYGTRLAVAAVNGPSSTVVSGEPDALDAYLATLTAQDVR
VRRVAVDYASHSSHVESIRDELLDVLAPVAPRAAEVPFYSTVTGTVIDTTGLDAAYWVRN
LRQTVEFETATRALVADGYTGFIECSAHPVLTLGLSQTADATAADIAAVGSLRRGEGDAA
RFVTSLAEAFVHGLRVDWTPLLDGAAPAADLPTYAFQRTRYWLENIDPETAEAVGAADVV
EAGFWDAVEREDLEGLAHTLELDADRLSDLLPALSAWRTRSREQSAVDAWRYHLSWQNLP
EHGDAPRLDGTWLLVVPRLPDVPETGDVTPGNGAPGPEAPHADAHAVAHWADACARALAE
AGAEVVRLDVDCSSAHHGLTGPLGTALADAPPIAGALSLLPLDQRSHPDHPALGRGTLAT
LALLRDLGRHSHDAPLWSVTRGAVATGADDRLTHPEQAPAWGVGRVAALEYPERWGGTVD
LPETADTLALRRLTAALARTDGEDQLAVRPSGLLAARLVRAPRPDRPAPAWRPEGTTLVT
GGTGALGAHLARLLAREGAEHLVLTSRRGADAPGAAELARELSESGARVTLAACDVADRD
ALAALLDRLATDGERLTAVFHTAGVVDDTIIDTLTPERAEGVARAKALAARHLHELTLGS
ELSAFVLYSSFASVFPSTGQANYAAANAYLDALATHRRGLGLPATSVMWGSWGGGGLADG
EIGERLRAQGVPPMDPGTAVAALVRALAEGDTVVGVVDIDWARVAPTAVSVRPYPLITGV
PEARRAIAPAGGADTADNDGNALAGRLAGLDRPARARELLRLVREQSAAALGHSDPDAVP
PSSPFRDLGADSLIAVNLRNGIAQATGLRLPATLVFDHPTPAALARHIEEQLFADDTPNS
AAPAPAAPVDADEPVAIVGMACRLPGGVTTPEELWQLLADGTDAIAPFPDNRGWDVDSLY
DPDPDAPGKSYVREGGFLYDAAEFDAGFFGISPREALAMDPQQRLLLETSWEAMERAGID
PGTLRGSLTGVYVGAGHRGYVTSLGQLPEGAEGYTMTGNASSVMSGRIAYTFGLEGPAVT
VDTACSSSLVALHLAAQALRRGECGMALVGGVAVMPDAEVFVEFSRQRGLSPDGRCKAFA
ASADGTGWAEGAGVLLVERLSDAVRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVI
RQALLDAGLTTADVDAVEAHGTGTKLGDPIEAQALLATYGQDRTDGHPLYLGSLKSNLGH
TQATAGIASVMKMVLAMDQGVLPRTLHVEEPSPEVDWASGAVELLVREREWPRTGRPRRA
AVSGFGISGTNAHVVLEQAPVSSGGVVPVSEVEPSEAVGAVGAVGGVVPWVVSARSEVAL
ADQVGRLASFVDGRPGVGVLDVGASLLGRAGLDHRAVFVGRDLDGLRAALSSGVDGVAGV
VGVGDGRLGFLFAGQGSQRVGMGVELAAAFPVFGGVWREVWSLLGLSPDEVAVERTGWAQ
PALFAFEVALFRLVESWGVRPEVVAGHSVGEVAAAHVAGVLSLGDAVRLVEARGRLMEGL
PEGGVMVAVGASEAEVVEVIAAHPRGEWVSVAAVNGPSSVVVSGVRGVVEEVVGGFVGRG
VRVRRLGVSHAFHSVLMEPMLGEFRGVLESLEFGVPSVDFVSSVGGGGDVGSVEYWVRHA
RAEVRFADVVGELGGRGLTALVEVGPDATLTGMAGQVLADPGGPVLVALCRKGRDEAVSV
VEGVGRVWACGVAVDWALLCGGGRRVDLPTYAFQRDHYWLQRSSGASDPVGLGLSGTGHP
LLGAAVPLADGGSVVLTGRVGRGAQSWVADHQVGGVVLLPGTAFVELAVRAGDEVGCGRV
EELTLQAPLILPERGGVRLQVVVEGPDATGGRPVAVHSRPDDGDTWTLHATGLLTEPVGA
EPDDLAVWPPADAEPVDLTSFYDELADAGSAYGPVFRGLRAAWRSAGEVFAEVALPDGVD
AAGFGVHPALLDAALHPIGLGGLVDAHKGVTLLPFSFGGVELHASGASVVRVRLTPVGGD
SVSLLVADAAGEPVVSVKALTLRPVSAEALRASSAGHDSLYRIDWVPLAAAEGPAPAAVV
LGAASELDDVAARGIPELLVTYVDPAADVRRAVGDTLVLLQRLLGDTRYDTTPLAVVTRA
GALAHTAVWGLLRTAQTENPGRFFLLETDQDLYDVAEVASAVATGENQLRSAEGQLFGPR
LARAVSADTLPVPSGAPNWRLAVRGGTGTLEDLVLAPLPDPADEPLRPGEVRVAVRAAGL
NFRDILIALGMYPGGGDAPAIGNEAAGVVVETGPGVPDLLPGDRVFGLLPDSIGPVARTD
HRFLARLPEGWSYETAAATPVAFLTAWMGLVELAGVRAGDAVLVHAGAGGVGMAAVQVAR
HLGAEVFATASEGKWGALRELGLDEAHIASSRSLEFRERFLAATDGRGMDVILNSLSGEY
VDASLDLLPRGGRFIEMGKTDLRDADTVRSGHEGVEYRAFDLIEAGAERIGGWLAGVVGL
LEGGVLEPLPVVSWDVRRAREAFRYVSQARHVGKVVLSVPRVLGAGGTVLVTGGTGTLGA
LVARHLVSVHGVRRLVLASRRGGAAEGVAELVVELEKSGAVVTVVACDAADRDQLAQTLA
AIPAEHPLTAVIHTAGVVDDAVLTSLTPEQVERVLRPKVDAAVNLDELTAGTDLAAFVLY
SSVGGILGGAGQGNYAAANAFLDGLAERRRARGLPGQSLAWGLWEEASGMTGHLGSGDRA
RTDRSGVRALTSEEGLALFDAALATDEALLIPVGLDLATLRARATAEEVPGLFRGLVRTS
GRRTAGVVNASGADALRRRIEAASGAEQHRIVLDLVRQQAAAVLGLGETGRVETERPFRE
AGFDSLTGVELRNRLGATTGVRLSPTSVFDHPTPAALTEHLLEQLAPGDEGAAPGGDRAE
ADFRRALADVPLSALRDAGVLSLLRRLTGFEDETEGPETAEHDAASIADMDVDALVDMAL
HKNEA
>G0PRM3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MQSSADQLIQALRAALKDNDRLRREHRELTTAVREPIAVVGMACRYPGGVTSPAELWQLV
GRGGDAITPFPRDRGWNLDELHGADAEEAGTSYVRRGGFLHDAADFDAEFFGISPREALA
MDPQQRLLLETSWEAVERAGIDPATLRGSDVGVFSGMMGQGYAWRLSNIPPEVEGYVGTG
NTASVASGRVAYAFGLEGPAITIDTACSSSLVAVHLAAHALRRGECSMALAGGATVMSTP
DTFVEFSRQRGLAPDGRCKAFSADADGTGWGEGVGVLLLEKLSDARRLGHPVLAVIRGSA
VNQDGASNGLTAPSGPAQEAVIRQALTAAGLTAADIDAVEAHGTGTRLGDLIEAQSLLAT
YGTGRPDGDPIRIGSLKSNIGHTQAAAGVGGMIKMIMAMRHGTLPRTLHAETATTAIDWS
SGAMALLTERLPWPERDRPARAAVSSFGVSGTNAHIILEAPGTDDGTPATALPPSADVLR
PWLLAARTPDALRGQAQRLYDLLSARPELRDADIELSLRTGRTPFDHRAVITGDDRETRT
GALAALARDERSPHVVTGQAVRGDAVFVFPGQGSQWIGMGLDLYETYPVFAEHLRACEEA
LDPYVDWSLLSVLRGEADAPSLDRVDVVQPALFAVMVSLAHLWRSLGVQPAAVIGHSQGE
IAAAHVAGALSLEDAARIVALRSRALRGLSGRGAMAAVSMSAEEAARRIENLRSTDNGGR
GGEDGSAGTDRRTGTDRRTGGDRRTEDDRRTGDDGGALSVAAVNGPASTVVAGSPDAVDA
FLDQAEADGFQTRRLPVDYASHSAQMEEIQQGLLDILADVTARPGTIPFYSTVTADVMDT
AGLDTAYWYRNLRQTVRFEETVRLLLDHAHRQFIECSPHPALLASVADTVADADVPAAAV
GSLRRDDGGRRRFLTSLAEAHAHGVTVDWAALSGPDGDRVDLPTYAFERRRHWLTSTQGG
SQGLTAAGLHSAEHPLLGAAVTVAAADGLLLTGRLGLDSHPWLADHRILDAVLVPGTALL
EIATHAARLTGAGGVAELTLESPLIVPDEGTVEIQVLVEDPDDDGRRTLTLHSRAGDTSD
APDSPDHPDEAAWHRHARGFLTVDTATATGTATDTDTATGTDAGMGADAFAPLTLSAAWP
PPGATSVPVDGFYARLAEADFQYGDCFRGLRAAWRHGQDLLAEVQLPAGHDTEAGRFGLH
PALLDSALHALGLGPFADGEGDTGRLPFSWSDVQVHRPGADRLRVRITPVEGTDTVSLHA
TDATGAPVLTVGSLALRPVSPELVRTATVSRASGGLLSRVEWPVCPRPSMPSGGRAVVLG
DDLPGWPATDRLPGPLLDHDLDERSLRETVPDPVPTDVVLVCAPVPTGPDGDAAEAARTT
VVRTLRLIQAWIADERLAGSRLVLVTRGAVEALPGEGVGDLEHAAMWGLVRSAQSEHPGQ
FVLLDIDDTDIAADLLRAALATGENQIAVRGGTLHTPTLTRVPAVPTATAAERPVDPEGT
VLVTGGTGVLGGLVAEWLVSVCGVRHVVLVGRRGGSEGVAGLVGRLAGLGARVRVVGVDV
SSRAGVVEALGAVEVGHPLVGVVHAAGVVDDGVVGSLSPEQVGSVMGGKAGGAWWLHRLT
EGLDLSFFLVFSSLAGVVGSPGQANYAAANGFLDGLMQWRRARGLVGQSVAWGLWDVTSG
MTGGLDEGDRARMSRGGITGLSTSEGLGLLQNAWHLPDPLLVAARWDTAAWRDAENVPTM
LRGLVRGGLGTPRSHRPAPAGLAERLTGLSGAQLTKTVVEAVRAEVASVLGFGSVVDVPV
GLAFREMGFDSLTAVELRNRLGVLFGVRLSATVVFDYPSVGALAEFVCGLVRVEGGVGRG
VSGGVSGGVSGGVPVVDAGDPVVIVGVGCRYPGGVVSGEGLWGLVASGGDAVGGFPVDRG
WDLGVLEGVGDVVPRGGGFVHGAGLFDAGFFGISPREALAMDPQQRLLLEVVWEALEDAG
VDAGVLRGSRTGVFAGVIPQDYVARLSSVPDESAGYVGIGNTTSVVSGRVAYSFGFEGPA
VTVDTACSSSLVSLHLAAQALRSGECSLALAGGVTVMSSPATFVEFGRQRGLAGDGRCKA
FAGAADGTGWGEGAGVVVLERLSDARRLGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQR
VIQQALASAGLSSVDVDVVEAHGTGTKLGDPIEAQALLAAYGQDRPEGRPLWLGSVKSNI
GHTQAAAGVAGVIKMVMAMRHGLLPETLHVDEPSPHVDWSAGEVRLLTEPVPWRAEGRPR
RAGVSSFGVSGTNAHVILEEPPAPVSSAAELSATEPVVAVPETLESLPWVVSGRDVAGLR
AQAAQLAGFVRAQRAAGAVDVLWPAGVAAGLAGRAGLEQRAVVTGTDVEALLSGLDAVGA
GEPSEGVTTGTATLGSGVVFVFPGQGGQWAGMGRELLGCDAVFAGAIDVCERALDPFVDW
SLREVLTGSDEKWLGRVDVVQPVLWAVMVSLAEVWRAAGVEPDAVVGHSQGEIAAAVVAG
RLSVEDGARVVALRSRALLGLSGQGAMASVALDVAEVEGVLPGSVTVAAVNAPGQVVVSG
PPDEVAELCVRLEGQGVRARRIEVDYASHHAQVEVVEGRLRGELGGVVDLGGSGTEFVST
VTGGPVAVGELGAGYWYRNLREPVLFADVVRRLDGEGPQVFVEIGPHPVLSLAMEQTVTE
GRVLHSLRRGQAERAQLLRSLGEAWAAGLPVGWRGLLPVVEPVALPTYAFQRERYWLDAP
PPVAAVGAAGSGVDGWRYRVGWTPLAVQHAGGLPRKWLLLCQDMADAGEARQALEQAGAQ
VEVRALPDDHDIDRAGIVQLLAGAEHIAYLPARVDGGRKAETEPAPGIGTGTGTETGTGA
DTETGAGAGVPSGLSAQLAVPLMVMQAVVEVEGARLWVVTRGAVSVSGGGSVPDPVLAAV
WGLGRVFGLEHAGHYGGLVDVPVVWGAGTGGLLVTALAQSVEDQLAVGADGVFVRRLRRA
PASLSGRGVGWRPGGTVLVTGGTGGLGSHLARWLARSGAEHVVLVSRSGRRAEGAVALAE
ELAAAGTPTTVRACDITDATQLAEVLGCTDHPPITTVIHAAGVSRDVVLTDLTAEDLEDV
LAAKVRGADLLAERLADGAFERLVLFSSNAGVWGGARQGAYAAANAYLDALAERLRAAGR
SVTSVAWGLWDAEGMGGGEAGARLSRLGLRPMAPDRAVAALHEALGMDETLVAVADVDWE
QFLPAFTMARRRPFIEDLPDARQITAAGDHEGADTNGASGLLARLDGLDAADRLDLLSKL
VCEEAARVLSHSSPDAIEPERAFRDMGFDSIASVELRKRLSAGTGLHLPATVAFDHPTPR
ILAEHLGAELLGVAPDVPSSTRVFGDIDRLAGTLAEVAEDDAVRKRVAQRLRELLDSCDT
TARNADGMSAQLGSASDEEIFEFIDKRFKRS
>G0Q9U9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MGRELAAAFPVFDASLGACARALAPYTDWDLRAELAGDLSRVDVLQPATWAVMVSLARLW
QSFGVTPAAVVGHSQGEIAAAVVAGALSLEDGARVVAERSRIIRRSLAGRGGMASVGLPA
DTVRARLAEVGEGLEVAAVNGPRSTVVSGDPAALDRLLALLEPEDVRVRRIAVDYASHSS
HVDSVRDELLEVLAPVRPRPGDVPFHSTVTGEALCTTELDAAYWVRNLRRTVEFTTAVEG
LAAEGHSLFVEMSPHPVLTMAVEETADGSLSAVGSLRRDDGGPRRFLTSLAEAHVHGTDI
DWAPAFPGANVVDLPTYAFQHRRHWLDGATARPTVADHPLAATVERLADGDGALLTGLLS
RSTTPWIPDHAVAGEVLLPGTAFVELLLRAGEQVGCARLEDLTLQAPLPLPGDGSAVRLQ
ISVREPEEGTGSRPFTVHTRPAGSAPDSPWTRHATGTLAPARAAAQASDPGLTNWPPPGS
EPVALEKLYGELASLGYAYGPAFRGLTAAWRHGRTVYAEVALPADRHPETAGYGIHPALL
DACLHAALLDRLDTDAARPALPFAWSGVELHATGATAARVRVVPAEPGSDTVAVTVADAS
GRPLVGVEALVLREAPVAPGPAEALPEGLYRVTWTPAPTPAPAAAPPGEWCAYGDELPDP
VPPTVVARVRTGPDVADAVNHALRTVQRWLADERCARSRLVLAVRGDTPAEAAVAGLVRS
ARTEHPGRFVLVHLPADASDADAASAASGDEPEIRSGAGSPTVPRLARVGADGVLAPPAE
GPWRLDVTDTGGLDRLALLPSPAAARTLAPGEVRVRMAAAGLNFRDVVVSLGMVPGLEGV
GVEGAGVVAETGPGVTRLAVGDRVMGLLPQAMAPVAVADARTLVRVPDGWTLRQAASVPV
AFLTAELGLVEGAGLGPGDRVLVHTATGGLGLAALQLARRAGAEVFATASPGKHALLRRL
GLDDDHIASSRDLGFRERFLDTTGGAGLDVVMNTLSGEFTDASLDLLPRGGRFVEMGKTD
IRDPGTVAADHPGVDYLYFDLLAEAPDRIRDGLDRLAAPLADGDLTPPLSSSRDIRHAPE
AFDTLRAATHLGKIVLTLPHTWDAERTVLVTGGTGTLGRLLARHLVTRHGVRHLLLTSRR
GPEAEGAGELVDDLRGLGAHATVVACDAADRDALAALLAGIPADRPLGAVVHTAGLLDDA
TVEGMTPAQVERVLRAKVRSAELLDELTEGIDLDAFVLFSSVAGVLGTAGQANYAAANAA
LDALAVRRRRQGRAAVSVAWGLWEQSSGMTGHLDGQDIGRLARTGTAPLASADGLALFDA
ALAVDEPGVVATRLDHAVLREQSPATLPAVLRTLAGTGRRRATAPAPGVESDDATLARRL
ADAAPAERRHTLLELVRNQTATVLRLSGAHEVEDERPFREVGFDSLTAVELRNRINAATG
LRLPSTVVFRHPTPAQLADRLHTELVPEQDTDGAATTVLADIGRLRTAVAGITDEERAAV
AEELSRLLTEVGGVEDLLNSAGQSDLAAATDDEMFALIDKELEME
>A0A2P4UBX4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinomadura rubteroloni|TrEMBL
MSCRLPGAPDPESFWELLRAGRSAIGETPADRWDAAALQDAGLVPTRRGGYLDDVGHFDP
AFFGVSPREAAAMDPQQRLFLELSWEALENAGIVPADLAGSRTGVFVGAIWDDYATLLHR
YGLEAITPHSVTGLHRGIIANRVSYTLGLHGPSLTVDTAQSSSLVAVHLACEALRTGAAS
LAIAGGVNLNLAPESTVGAAKFGGLSPDGTSYTFDARANGYVRGEGGGAVVLKPLAAALA
DGDPVYCVLHGSAVNNDGGTDGLTVPSADAQAEVMRLAYGHAGVEPAQVQYVELHGTGTK
VGDPLEAAALGAALGTARLGRPPLRVGSAKTNVGHLEGAAGIVGLLKAALAVHHRELPPS
LNFATPNPEIPLDDLGLDVQTDLTPWPAPDLPLVAGVSSLGMGGTNCHVVLAEAPSRDVP
AASPARGPLPLLLSGRSGAAVQAQAERIAARLRAGLDSADAAFSLATTRTAFERRAVVVG
GTRDELLAGLDGVTSDVPVAAPGKLAFLFTGQGSQRAGMGRELYATYPVFAEALDAVFER
IDLPLKEVMFGDDPRLNDTQYTQTSLFALEVALFRLLESWGVTPDHLLGHSIGELAAAHV
AGVLDLDDACTLVAARARLMQSLPTGGAMVALQATEDDVRPYLDDSVSIAAVNGPASIVV
SGDAEKVEQIAEHFKARRLTVSHAFHSPHMDPILDEFREIAATLTYREPEIPIAANTTGD
LTTPEYWVNHIRNAVRFHDGLQELQAQRVTACVELGPDPVLAALARTALPDAVAASALRR
GRPELRTLFTAVAHVRDVDLTRTFTGGRRVTLPTYPFQRERYWFDTTRAARAALRLAETS
EDTGGSDAGELAGRLAGLDEAEQERVLLDLVRTAVAIVLGHVTPEAVETDRAFKDLGFDS
LSSVELRDRLAGMTGLRLPPALLFNYPTPKVLVRHLRAELTGGGTASAAAVATVAADEPI
AIIGIGCRYPGDVRSPEDLWRIVADGVDAVSGFPTTRGWDLDALFDPEPGRPGRTYAREG
GFLHDADRFDAAFFGISPREAAAMDPQQRLLLETSWEAIERAGIDPSALRGSATGVFVGA
TAQDYGPRLHAAEEGLSGYLLTGNTASVASGRVAYTLGLEGPAVTVDTACSSSLVALHLA
AQALRQGECGLALAGGVTVMANPGMFVEFGKQRGLAADGRCKAFAAAADGTAWAEGAGLL
VLERLSDARRNGHPVVAVLAGSAINQDGASNGLTAPNGPSQERVIRRALAGAGLAPHEVD
AVEAHGTGTSLGDPIEAEAIIATYGQGRETPLLLGSLKSNIGHSQAAAGVGGVIKMIEAM
RHELLPRTLHVDAPSPHVDWSAGAVDLLTEPRPWSRGDRPRRAGVSSFGISGTNAHVIIE
EPPAAEPAATSAGTGPVAVPVSARTDGALQNRAAALHALVEADPSSDVRALALSLATTRT
AFEERAAVVAADRDELLAGLDALASGATHPSLVRAMAGSGRLAFLFTGQGSQRAGMGREL
YETYPVFAEALDAVFARIDLPLKDVMFGDDPRLNDTQFTQTALFALEVALFRLYESWGVK
PDHLLGHSIGELAAAHVAGVLDLDDACTLVAARARLMQSLPTGGAMIALQTTEESVEPYL
NDAVSIAAVNGPNSIVISGDEAAAEEIAQHFKARRLTVSHAFHSPHMAPILDEFREIAAT
LTYHQPKIPIAANTTGDITTAEYWVGHIRNAVRFHDGLRELQAQGVTAFLELGPDPVLSA
LARTGLDGVDAAFAALRRSRPEARTVVLALAQLHARGVALDWPAFTGPAGRVDVPTYPFE
RRSYWLAPNAGTSLAAAHGLLGAPISLADGGQILFTGRLSLANRAWLADHVIAGATLLPG
TAFVEIALEAGRQTGHDRLADLTLERPLILPATGAVEIQAIVGPVTGDGGRTIGVHSRPA
GDDEAPWTRHATGTLTWDDASATPQGGVWPPEGAAPLDLADLYDRLADGSYAYGPAFQGV
TAAWRRGDETFVDLRLPADLEPDAARFGVHPALLDAALHLVVLSEEPTGPPRLPFAWTGV
GLHARGATELRARITPSGPDAVSLTLTDAAGAPVVSVAELTLRQADPAALAEADDALFHV
EWVPVPAQEAAGDLTVVRLPDDPATALDAAAGALARVQEWLASGAQGRLAVVTRGAVRVG
ADDSPPDPRVAAAWGLLRTAQSEHPGRIVLADVDDPATAERAVATGGTDQFAVRDGAHYA
PRLARLAAPAAPAPALDGRVLITGGTGALGGLVARHLVTAHGARDLLLVSRRGPDAPGAL
ELEAELTAHGASVTIAACDTTDADALAALLAEHPVTAVIHAAGTLDDTTVESLTPERLAT
VLRPKADAAWTLHRLTADNPDLTHFVLFSSISTVIGNPGQANYAAANGFLDALAEHRAAS
GLPATSIAWGLWDESGGMAGENAGAGRSRLGRQGVAALGTEHGLALLDVALGLADPTVVA
VALDTAALRARAADGTLSPLFRGLVRAPARRAATAAPSSLAQRLAGLSGPAQEEEILALV
RTATAAVLGHDSPDALDTDRAFKELGFDSLTSVELRNQLNTATGLVLPATLVFDHPSPAA
VAAFLRRRVSGADRPAAVTVRATAAADDPIAIVAMACRYPGDVNSPEDLWKLVADGVDAI
STFPANRGWDLDALYHPDPDHTGTSYSRHGGFLHDAPAFDPDFFGISPREALAIDPQQRI
LLEVAWEAIERGGIDPGALRGSRTGVFAGVMYDDYGARLRPAPEGFEGYVGNGSMASIAS
GRVSYTLGLEGPAVTVDTACSSSLVALHLAAQALRNGECELALAGGVTVMSTPATFIEFS
RQRGLSPDGRCKAFSASADGTAWSEGAGFLLLERLSDARRNGHPVVAVVRGTAVNQDGAS
NGLTAPNGPSQERVIRQALAAARLAPADVDAVEAHGTGTSLGDPIEAQALLAAYGQERET
PLLLGSLKSNIGHSQAAAGVGGIIKMIHAMRHGVLPRTLHVDAPSPHVDWTSGAVELLTE
PRPWPETGRARRAAVSSFGISGTNAHVIIEEAPGEPAAERPDVPAVWPLSARSPEALRDH
AARLAASAAELDPADVAFSLATRSRFPYRAAVVGASRDELLDALGALARGETAPHHVEGR
AKLAFLFTGQGSQRAGMGRELYDTFPVFADALDAVLDRIDLPLKEVMFGDDPRRNETRFT
QTSLFALEVALYRLFESWGVTPHHLLGHSVGEIAAAHVAGVLDLDDACALIAARGELMQS
LPPGGAMIALQATEESVEPYLNDAVSIAAVNGPNSIVISGEEAAAEEIAQHFKAKRLTVS
HAFHSPLMDPILDEFRAIAATLTYHEPKIPIAANTAGDITTAEYWTNHIRNAVRFHDGLR
ELQANGVTTYLEIGPDAVLATLADGPAASALSRKKPERAALDAALAHLFQTGVPVDWTAV
PAGGRHVELPTYPFQRAEYWLAPPAATGDLGAAGLTGTGHPLLGAVLEPADGDGLVLTGR
VSLAAQPWLADHAILGTPLLPASAFVELAAQAGRRLGLDRVEDLTLEQPLALTPAGAVQL
QVVVAGPDASGTRPVAIHSRTADEPGWTRHATGALSDRVPAAEPLPAAWPPPGATPLDVD
ELHDDLAAQGYHYGPLFQGVTGLWKLNDTYYADLSLPGDTDVAPYAVHPALLDAALRPLT
VDNEPGRIRLPFSWSGVTFHGTASPAAARVALTPTGADTVTLTIADAATGAPLITVDALG
VRPYTPDGPHRDALFGLAWRPIRPASDQPQSWTVVGADAALTTALGATASDGLPADAAGP
VLLPAGWSGDPAEGVHAETARVLGLVQAWLASDATTPLVVVTRGAVATGADDDVTDLAAA
ALWGLVRSAQAEHPDRLVLLDADDDEASLRAVPAAVASGEPQLAVRGGAVHVPRLERRRA
SAEAVSPFGGDGAVLITGGTGSLGALLARHLVERHDVRDLLLVSRRGPDAPGALELEAEL
TAHGASVTIAACDTTDRVALAALLAGRTVSAVVHAAGTLDDAIVESLTPERLATVLRPKA
DAAWNFHRLVPETPLFLFSSVSGVLGTPGQANYAAANTFLDALAQHRRANGLPGASLAWG
LWAETGAMTGTLSDADLARLGRGGILPLTAEQGLALFDVAVASDAALVVPARLDLAALRA
EPPAVLRDLIRTPVRRAAAPASSLTDRLRRADADERDTILLDLVRTNVATVLAHATPETI
DPHRGFSESGFDSLTAVELRNRLNTATGLRLPATLVFDHPTPAALTAHLKHELLGTGDAL
VPAAPAGRAEPDEPIAIVAMGCRYPGGVATPEDLWRLVAGGADAVSGFPDNRGWDLERLY
DPDPDRTGSSYAREGGFLTDADRFDPAFFGISPREALAIDPQQRILLEVAWETFERAGIT
PDSVRGSATGVFTGVMYNDYGSRLHTAPEGFEGYLVTGSAGSVASGRIAYTFGLEGPAVT
VDTACSSSLVALHLAAQALRNGECGLALAGGVTVMATPATFIEFSRQRGLSPDGRCKAFA
AAADGTGWGEGAGLLLLERLSDAEKNGHPVLAVIRGTAINQDGTSSQLSAPSGPSQQRVI
RQALAAARLAPADVDAVEAHGTGTRLGDPIEAQALLATYGQDRETPLLLGSIKSNIGHTQ
AAAGVAGIIKMVEAMRHGVLPKTLHLDEPSPYVDWTTGSVELLADSTPWPDVGRPRRAGV
SSFGISGTNAHVIIEQPPAAEPAAPAAPAGPLPLVLSARSPEALRDQAARLGAALGDVDP
VAAAYTLAATRTVFDHRAVVVGDRDGLLRGLDALATGTPADNVVQGAAGPGKLAFLFTGQ
GSQRAGMGRELYDAYPVFAEALDAVFARIDLPLKDVMFGDDPRLNDTQFTQTALFALEVA
LYRLLESWGVKPDRLLGHSIGELAAAHVAGVLDLDDACKLVAARARLMQSLPTGGAMIAL
QTTEESVEPYLNDAVSIAAVNGPNSIVISGEEAAAEEIAQHFKAKRLTVSHAFHSPLMDP
ILEEFRAIAATLTYHEPKIPIAANTTGDITTPDYWVGHIRNAVRFHDGLRELDDNGVTTL
LELGPDPVLTALARTAFTEVAAASVLRRKRPEVPALLAALGTAHAHGAKVDWTRIVPASA
LAPLPTYPFQHARYWLDAPATGEPADADGLGLSATGHPLVTAAVEDVEGDGLTLTGRISL
RTHPWLADHAVSGTTLFPGTGFVELLLHAGSLAGAPHLADLTLESPLVLPADAPVRLRVV
VGTAAEDGTRTVAVHARAGDGPWTRHASGALTTAGSAPEPVRVPDGAVPLDAADHYENVA
DLGYGYGPAFRGLRAAWRDGDDAYAEVVLPDGVDAAGYGVHPALLDAALHALGLVRDLTG
EVPFLWSGVTLHGAGATALRVRLAPAGDDTVRLTIADQAGNPVLTADALTLRAIAVERNR
RASTLFDLDWVPVAPAAAPADVVPLAGDPAALAADGRFVLAPVAPDDAHATAHVALALVQ
EWLAADAGRLVLVTRDALTDPAQATVWGLVRSAQTENPDRFVLLDLDGDPASEAAVPAAL
ATGEPQLMIRAGVPLVPRLVRAADAPGTPITPDPDGTVLITGGTGALGSLVARHLVTAHG
ARHLLLTSRRGRDAAGAADLEADLAALGADVTIAACDTADADALAALLATVERPLTAVIH
SAGVLDDGVVTSLTPDRLDTVLRAKADAAGNLDRLVPDVPLVLFSSAAGILGNAGQGNYG
AANTFLDALARRRHAEGRPATSIAWGLWDGTGAMTGTLTDTDRGRLAKAGVLPLSAEQGL
DLLDAALGAGGPVTVATRFDRTALRALDTAIPAVLRGLVPAPARTAPAGRDRDTLDLVRE
AVAAVLGHADPAGIDTGQAFKELGFDSLMAVELRNRLNTATGLRLPATLVFDYPTAAVLA
RHLAAELSGGAEEITAGTTAAAVDDDLIAIVAMACRYPGDVNSPADLWKLVAGGVDAITP
FPSDRGWDDDLYDPDPERAGRSSTRHGGFLHRAADFDPAFFGISPREALAIDPQQRILLE
IAWETFERAGIDPAAVQGTATGVFTGVMYDDYAGRLLDRRPDELDGYVGTGSAGSIASGR
IAYTFGLEGPAVTVDTACSSSLVALHLAAQALRNGECSLALAGGVTVMATPSTFVEFSRQ
RGLAPDGRCKPFSAAADGTAWAEGAGLLLVERLSDARRNGHPVLAVLRGSAINQDGASNG
LTAPSGPSQQRVIRQALASARLTPSEVDAVEAHGTGTRLGDPIEAQALLATYGQDRETPL
LLGALKSNIGHTQAAAGVAGIIKMVEAMRHGVLPRTLHVDAPSPEVDWDAGAVALVTEDV
PWPETGRPRRAAVSSFGISGTNAHVIIEQAPETAAPEPAGAPRTLPWLLSAKSDAALRDR
ARDLRDRVAAAPELDAAAVARALRGRPAFDRRAAVVAADRDGFLAGLDALASGSGHPGVV
EAATSTGKLAFLFTGQGSQRAGMGRELYETYPVFAEALDAVFARIDLPLKDVMFGDDPRL
NDTQFTQTALFALEVALYRLFEAWGVKPDHLLGHSIGELAAAHVAGVLDLDDACKLVAAR
ARLMQSLPGGGAMIALQTTEEDVQLHLTDAVSIAAVNGPKSLVISGDEAAAEEIAQHFKA
KRLTVSHAFHSPHMDPILEEFREIASTLTYHQPTIPIAANTTGDITTPEYWVGHIRNAVR
FHDGLRELDDNGVTTFLELGPDPVLTALASTALADATAAPVLRRKRPEAITALAALSTAH
ARGAAVDWDAVLGAGPAHVDLPTYPFQRGTYWLDAPAAAGDLGSAGLGTSDHPLLSSKVE
LASGEGTVFNGRISLRTHPWLADHAVSGTVLVPATALLELAAAAGRDTGLDRVAELTLDA
PLTLPEDGSVRLQLALDAPDDAGERRFALYSGADDDQPWTSHATGVLANATAADTPSTRP
PAMAEAIDVDGLYERLAERGYDYGPLFQGLRAAWRDGDDLYAEVALPSGTDTAGYEPHPA
LLDAALHVLLLDQADDALQLPFSWTDVTLHGAATEARVRVSPTSNGVAITVTGTDGTPVA
SVASLAVRPLTLPARGNDALFVLGWTPVQTPARTEPGRWTVLGAGLDDLPGTVEHYADLA
AVPPTETIIVPVTGADGDAAASAHATARTVLDLLQSAPATARLVLVTRGAVALDDAADLG
AAAVWGLVKSAQAEDPGRFVLLDLDDDAASVRAVPAALAAADELDEPRLAIRAGAVHAPR
VTRPAEPAGEPLTLDGTILVTGATGALGGLVARHLVTEHGVSDLLLVSRRGADAPGATEL
ETDLIALGATVTFAACDTADRDAVAELLDGRNLGAIVHTAGVLRDATLTGLTHDHLDQVF
RPKVDAAWNLHTLAPETPLVLFSSLAGVLGNPGQANYAAANTFLDTLAQHRATQGLPGTS
IAWGLWDEPGDLTDNLSDTDRARMAETGVLSLSHEQGLALFDAALAQAAPVVVAARLHTT
ALRDQAAAGTLSPALRGLVRVPPTRRAAPAATLALDGLDPEERLRELTRLVRSQAAAVLG
HADADGVDPDRGFNEIGFDSLTAVELRNRLGGATGLRLPATLVFDHPTPNALARHLSGEL
GAGGASTASVLAELDRIEADLAALAPAGEDRRVLTGRIQQFLARLGETDGDPGETEVAEQ
IGSASDDEIFDFIDNELGIS
>H1KUJ0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Methylorubrum extorquens DSM 13060|TrEMBL
PAEAARVTAAAFHRRERLATRLALPLTPETDVPAALRALAEGEESDAAIVGTAVERQAEV
AFVYSGNGSQWVGMGREAYEESKAFRARFDQTDKLFEKLSGWSLKEAMFAEDLDARLSLT
RVSQPLIFAIQSASTAALRAKGIAPRYVLGHSVGEIAAAEAAGILSLEQAVRVIFYRSKH
QESTRGFGTMAVLLGPAEEMEAFLADYPTLDIAAYNSPKAITVAGPEADIEAAMKALARK
RRRGRKLDLEYPFHGRLMDPTERPLLRDLDGLKASAGHTAMVSTVTGTVLPGAQFGAGYW
WRNIREPVRFCEALQEATRQGARVFVEVGPRATLLPHIGDAIEPLAIEVASVGVMHRKPI
GGDPIAKAVAAALVAGAAVDEARLFGADPAGIIALPLYPWQRRPFRLAETTEGAGAAPRP
YHPLAGARLAPDGLEWHGHLDAALVPELDDHRIDGQVILPGAAFVEMALHVARQALRTES
VTISDVEILSPMVFAEDSLREVLVRLSGSGNQIQILSRPRLTPTPWQLHASAKIIEGDFP
VPARRDLAVPAEHAISGDGLYRRALASGLGFGENFRQVAASARIDETTIVSELIPAESDD
RYGLVPARLDSCFHGLILLFAELMGEGATKAYVPVRFGEVRLLRPGAAIARAEIRTRRCN
ERSILADFTLTDAEGEVVATIREGRFQALRARSGSDLDAYAITQGVERATEPTALPLERR
PSVAERLRPSLAAATAPDTADLGPGHLLLEGWATALAYRLADGLSEKGKVTLDRRLPAAL
HPWATNALYALESSGLATLEKGVWRLRRDVSLPAPEETMRWIAADHPELAAELVLLADTT
ALVGRIVAGDAPASASLPPAALDAFHLRGATARAAADVVARIVAEARGRMPSDRALRILQ
VGFGPLSARAAALAREADARLTVLDTDRRLAERARLALPSTVEVIEDIDALPPAAFDLVL
ASDVLHRADKALPGQLAAALASGGLLVAVEPGASLFRDLVFGLAPDWFEEAVAGMPLSRL
DDVTGWQRRLSASGLVRVSADRAASANGDDLLLVAEAPVRSAVGHGQSFAFVVGSHDEFG
AETASSLATLLVASGVHVSIILDSEQSLRELERETPDTVVFLAGAFAGEGAAATRLRDRC
LSLKRCAEFLGSRQTRLWVVAPGATRDAGGEAAAVEAGVWAFSRTLANETATLDVRRIDL
APTLSSKDAAERLRALILSGTDETEIVLDADATRVVRFHPGRAATTAGEAAPAARLE
>A0A1D2I3S6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. AVP053U2|TrEMBL
MLVEVSAHPVVATGVRETVEDAGVAAGVVGTLRRGEGGWERFTLSLGEAWAYGADVDWDV
FYAGTRPRRVDLPTYPFRREWYWLTPDETDRPAGTGSDPADGEFWSAVESGDVTRLSTVL
DITGDDTEAFSSLLPALASWRRRRALRTTLDSWRHCVHWMPLTGAAGPVPAGRWPALVPA
GHADDPWVDDVLAALTARGLRVERHDLTGAEDTAALTALLTTSDGGDPAGVLSLLALDER
PHPDHPAVPRGLTAAKDLTHALSGTGTRLWAITRGAVSVDSRDPLTSPVQAETWGFGRAV
AFELPDTWGGLVDLPPTPDPRALDRLPGLLDGTEDQLAVRASGSYARRLARMPLPEPAGD
TDPTGAWAAHDTVLITGGTGALGAHVARSLAAAGTRHLVLSSRRGPDAPGVADLTADLTA
HGARVTVADCDVADRDQLAGLLESLPADLPLTGVVHAAGVLDDGVLDALTPDRFDAVLRP
KTLGTANLHELTRDHDLSMFVLFSSVVGVLGNAGQANYAAANAYLDAVAEQRRAAGLPAT
SVAWGPWADAGMATADVLTDRMRHDGLTPMAPDTAVAALRAAVTEGASHATVVDVDWPSY
AGVLTAARPSPLIGDLPEVRRALQAAKAAAPDTHALHDRLRGLAPADQDRLLTDLVRAEV
ATALRYASPEAVDVHRAFKDLGFDSLTAVEVRNRITAATDVKLPTTLLFDHPNTVAVVDH
LKGRLLGEQQRTAAPVVVAAGVTDEPMAVVAMACRFPGGVTSPEELWDLMVAEVDAVSTP
PADRGWDLDSLYDPDSERQGTTYSREGGFIQDVAGFDPAFFGISPREALAMDPQQRLLLE
TSWETFERAGIDPRTLRSTATGVFVGTINTDYQVRLGGAAAQEQLAGHLMTGNASSIASG
RLSYTYGFEGPAVTMDTGCSSSMVALHLALQSLRTGECTMALAGGVTIMSTPEPYVEFSR
QRGLAPDGRCKAFAEGADGMGFAEGVGMVLLERLSDARRNGHPVLAVVRGSALNQDGASN
GLTAPNGPSQQRVIRQALANAGLSAADVDVVEAHGTGTPLGDPIEAQALLATYGQGRPAD
RPLLLGSLKSNIGHTQAAAGVGGMMKMVLAMRHGMVPKSLHITEPTSVVDWSGGAVRLVT
EATDWPDADHPRRAAVSSFGISGTNGHLILEQAPEPEPADGAGDPVAETDGVLTEAVRAP
AWLPWVVSAKSREAVREQAGRLAASVRGSGAGALDVAHSLVSTRVAMEHRSVVERRRRDR
TGRCVRLPGPGFAVGRHGRRTPGDLAGVRPADVCLRRRARSSCRVVVA
>A0A1M8GEZ1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus subsp. abscessus|TrEMBL
MTAVHVDPVVISGMAIEAPGGIDTPAAFWNALADGRELISAFPRDRGWPVDELLSLSNLD
GWGRISDAGGFITDASAFDPTFYGITQREAVAMDPQQRVAMRVAWKALENTGLNPGAVDG
SEAGCFIGISPNEYGPPVGEVNAHSGMRVVGRGQLGAAGRISHGLGLIGPSVCVDSACAS
SLAALHLAASAVRADECEWAIAGGVCVMGSPGGFYEFSRMHALDPDGHCRSYSDEANGTL
WGEAVGMVVLERESRARALGHRVYGRIMAVRTNHNGGGKPILVPRGRAQAKLVAATIAAS
GVDPADVGMLEGHGTGTRAGDPLEILALQSTYGAGGSNALLGSAKSNAGHAQSAAGMVGL
IKLLLSGQHGHIPPTLFADNPTTKIDWSMTGIRLATKLHPWEPKDGIRYGSVSSFGAGGA
NAHAIIAMPAMDAQGEDGDDF
>A0A1S8TUN9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Clostridium sp. BL-8|TrEMBL
MKDNNIKMSISCGKPITNKYCNKMNIGNLLIEAAENKKDKGILLVQGNDSDIFLSYEEIL
EKAMICLGALQEKGIKQDDFAIISFQNNIDFIICFWACVLGGIVVVPISTPSAFKGKNAS
LEKLINVWNTLEKPVIISDESIIKGMKNNELYSECQEMNMLDISILRENTIKGKMNLSEI
EKTAFVQFSSGSTNTPKGVILTHKNLLTNIEGIIESGGLTSEDRVLSWMPYYHDMGLIGF
HISLIALGMFQINMNPMKFVKRPTLWFDLISKHKITMTSSPNFGYRLLLRKVKDNHLKEW
DLSSLRLIFNGAEPISMPLVNEFMEKLSECNLSETSMFMVYGMAEACLAVSFPPVNSKPL
SHFISRNSLVNKSEVEEVDEGAKDALQVADEGYPVAGMQVRVVNDDGEIVPENVLGEIQI
KGDNVTKGYINNPEATAKSFQDDWLKTGDTGFIIDGRLCVTGRIKDIIFVNGQNFFAHDI
EFKLEEIEGVETGKVVVGGWHDEKEGREKIAIFSSLRVKEDELKSFYGNMLSKISETFGI
YIDFVVLVKAIPKTTSGKVRRFMLVQSFLDNEFADSTLTSSELLLNIEEKAEEADEGKSL
DLNISRDKIKEIWADVLDRPAQSIGYNQSFFSLGGTSIKAVQVLGMLEDELDITLGHDIL
INCRTINEMEEYLKNFSESNNVLTNIDEKMSGKVDEDDEIAVIEMSCRFPEASSPEEFWD
NIVSGKCSISEVPEERWDVNQYYSTSGDPTKTYCKTGAFIDKPFDFDAKFFNISDEEAAV
MDPQQRIILELVFEILERAGYSKKKVSGESISLYIGAGTNTYQEYHFNTLNMSSLKNFDS
FNSLSKEVQESILEEWKNKLGVTEFHTNLLVDNILNMIAARTSQEFNFKGPSMVVDTACS
SSLVTIHLACEALKKGECELAIAGGINLLLTPTPYIYLSNAGALSTSGISRVFDAKADGL
VPGEGAGLVLLKPLKKALKDKDKVLAVIKASAINNDGHSIGVMAPNPDGQREVIESLYVK
SGINPRDIQYIEAHGTGTKIGDPSEVRALSNAFKRWNPESNSMAIGSVKANIGHLLNGAG
IASFIKVILAINNKTMPPNVNLDELNLSIKFDKTPFYTMLEARKWEAQEGKMRKAAVNSF
GFGGTNCHMVLEEAPSEIIPAVEIQDYSRSKHALNLSANSKKSLQLKINNLVKYLKTSKE
NNLGDICYTENVLRTSFNKYRYSVVSESIEDLINELQNIKVEELNGDAQHKVALMFTGQG
SQYVGMGRELYNKLPIFKGYVDECSEVFYPYLNEKITDLIYSDKADESILAQTNITQPVV
FTMDYAFGRLLIDLGIKPAYMLGHSVGEWAAACLADVITLKDAAKIVSARGKLMGSIKSS
GCMCAVFTSSEKLEILFKEFEGAVWIAAYNGTHQVISGDEADVEKFCNNLLKEGIGFKKL
KVSQAFHTPLMEPILDAFREVLKEVKFNSPKIPVISNVTGKIMDEAFDIEYWINHILSSV
KFEQSIKHLSDKAVDILIECGPDRVLSRMASGVQAQSARIILSLSDRKMESFDVCLAALS
SLFTLGFNVDFEKFESEIYYNKLQLPSYPFERKTYKPDFGDESIRVPDEWFYNWNWKPEP
HKDINLEIKGNIVVFSDDSGIKDEIEEIFKLNKIYVVKAGTEYSFDDYSKFTINPIVEED
YVKVFNTIQGPIGAVIHLWNLNNKSLKLEFAFDDKVMHEDIYSVLYVGKALSKLNIEKTK
LLLVTDNGVSVNEENKISSPHQATAITFAQALDQENAFIDSYCIDIDKKEYESNREIAQI
LSDEIKHDLSKEGIVAIRGGVRFIRELSNSIELNQTSKIKFNDGETYLITGGASAVGSEI
AKVIAKKAKINLILTGREELPLVEKWEEELANNTRHAKKISIIMELKELGANVIYEAVDV
TKIGDMKTLVERIADEYGAIYGVIHAAGTFDSKTFKLLDKDIKTINKIIEPKLKGGIITD
LVTRKEPLKFFVMLSSVSCSEKLWSAGVGDYAAANAFLSAYSYYRAADNAPGKTIALNYS
LWAGTGMGSDFGNGALLALKAQGLNPLPAKKAAEAFIRALSVESQNVIHIIDKIEISDVE
KPSTIKMSPVNSRKLKNIKEIVYKVIAKQLKVEEDNFDVGKNFLELGLDSLGAVKVMEML
GTSIGMELYPTLIFEYQTPQALAEYIEKTYLEGFEEAAVSKIDDLDIEVIKNEKSKDIAI
ISASLRIPGANNLNEYWRILENGECVIREIPEDRWPANDHYSADMNSAYTSYSKCGGFID
NPYEFDPLFFGMSPSEATVTDPQQRIFLEIAWEVMQQAGYGGRYSTNNIGVFVGSEQNGY
SEHFNNYRIYMELKDKLLKNQTFNNMESNEKNEIMSNILNVLKPAKMVPDAVAGNSLNEV
AARVSHCLNLSGPSLTVNSACSSSLSALHLACESIRTGQCKMAIVGGVNLNTSPTPFIGL
SRVQALSKTGACYPFDDRADGMVLSEGASAILLKPLEDAIADNDNIMAVIKGSAMNNDGH
SQGITAPRPQGQADAVIKAYLDAKINPETVSYVETHGTGTPLGDPIEIEGMTKAFRAFTS
EKGFCAIGSVKSSIGHMLSASGITSLIKVVLALENKKIPHTINYNKTTTNRNIDFANSPF
FVAAEKTMEWERSGVTPLRAGVNGFGFGGTNVHVILEEAPEKKHIEKGEEDFPYLLQLTG
RNQSVIKNIALNLKEYVKGHEGLNTASICFTINSNQKELSTKNSAVVESKEHLLEILTHL
INNEDSECIYKGRSNPNRQTEAYLILDGNMKKVEKCKEDLSSRFDAFNIAYKECLKVVEK
NISNEKILDFESFAVQYAFGVLLSNFEMKLYGIIAEGTGILAASVLTGKMSLKQALEEIV
GTIRAEKDDVLEGDKNAVYLNCSILTSTGVLEDVFNISQNDDKNIRSLNGFVNKNQVIIY
PGNLNEIKNKEFYDDKNFNWIDMDISRDSVKSIMSVLAKIYTLGVRFNPSKLFNDNIKKV
MLPTYPFENETYKVSFEEELTYKEADYISMQRSGLRKMEMKHALSNSEKRSISNQLAIDI
EK
>A0A178X0E4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Amycolatopsis sp. M39|TrEMBL
MTADISQVPRDGTVFLFPGQGIDPSGALRTVFDGTNRHLPTNPSTVDATIDEIGEISASH
GYSHGSALRDLLLGERTLEQVPYGTSTLAQFAASVSVFRLLADADVIPDAIVAMSLGEAA
ALACAGSFDLAEATRLVCLLNDTYRKAVGRGTMVLVHADEETTRDLLSRTSQVSLVIASV
NTPAQVVVTGPSEAVTKLMALPGPLRTPLPVPYQAHTPALRPLRDEFLHRAAGTARRAPR
IPVCSAARQRCYACDDDPVEGIADNFVTPVNIVTVLKPLAPAGSRRFFEIGAGGSLTRCA
AEVLPGAHTTAPLVSGSATRRAR
>B2J2F3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MKSDKSDKSVSINRINRQLQHNPIAIVGMASLLPQARNLREYWQNIVNKIDCITDVPSTH
WSVEDYYDPNPRTTEDKTYCKRGGFLPEVDFNPMEFGIPPSILEVTDVSQLLSLVVAKEA
MEDAGYGEKREFNREMVGVILGVAMAKQLGMPLSARLEYPIWEKALKSSGLSDEDTQKIV
DKIKSAYVKWDENAFPGMLANVVAGRIANRLNFGGMNCVVDAACASSFGALKMAISELVE
HRSDMMLTGGVDTDNTIMAYISFSKTPAVSPSENVKPFDAKSDGMMLGEGIGMIVLKRLE
DAERDNDKIYAVIKGIGTSSDGRYKSIYAPRKEGQVKALERAYEDAGFSPATVGLMEAHG
TGTMAGDPTEFGSLKDFFDVHDDKKQHIALGSVKSQIGHTKAAAGAASLIKTALALHHKV
LPPTINITEPNPKLNIKNSSFYLNTQTRPWIRPEGEAPRRAGVSSFGFGGTNYHVVLEEY
EADQNAAYRLHSDASEVLLFAPTVEQLLSKSEDILGKLRSRSDSGGVSPEAITYYAQLVK
KCKSPQIPLSAPRFGFVAENLEEACKFLQTSIDWLKLKGTAASWEHPQGIYYRSSGMELG
GKVVSLFSGQGSQYLEMGRELVMNFPLMRRLHGYMDSLLLKDNLQPLSEIVFPHPVFGEA
EKNVQVAALQRTEYAQPAIGVLSAGMYSILQQAGFKSDFVAGHSFGELTALWAAGVLSTE
DYLFLVKARGQAMAAPEDPDHDAGSMLAVKEDISKVEAVLRHFPQVAIANQNSPTQFVLA
GPTAEIARIKEALHEKGYTAVLLPVSAAFHTPLIAFAQKSFAIATKSVKFQSPKIPVYSN
VTSKQYPKEAQGIQKILETHLSNSVLFKQEIENIYAAGGTCFVEFGPRRILSNLVKEILG
DRPHITVSLNPSTQKNSDRSLREAVVQLRVIGLALNNLDPYQLPQTIPPIETKKTLNVRL
NGINYRSEKTKNAFALALQDGHKVTLPTPEYPDAAPLFSSPGVTPPLAVIETNGHKKTTP
VMNGVTSNIITQPEQQMNPVTLPQPVQESKMQPTPEKLTNYEQLLASLEYLLTQFQENQA
ENLQVHGTYLNHQMEYAKAFFQLMQQQNSLLSESKSTAETAKMKLVVMESLERSMMQFHS
QQSETLRIHEQYLQEQLEYTKSFFQLIQQEYSQIISGEGVTQLTEKLSDAVRHHFTTETT
VTDAPTKIVESQPLPVAITQEPLPAAVEPVVETPAPIQTRSIASLPTPHFATVETVEPVI
APPVPVVEPQAEVVVKISAPPVEEVVAFTPEPAPTTAAPVSGATIDIVDLDKNLLAITSD
KTGYPVEMLEMDMDMEADLGIDSIKRVEILGALQEMYPNLPKPNLEELSEKRTIGQVVEY
LQSHASKSVSVEIAIHEVQQTTEISVEVAPVVEVVVAPEPSVVVAFTPEPEVASSTSDEF
ANLGETLLAITSDKTGYPVEMLELEMDMEADLGIDSIKRVEILGAMQEMYPNLPKPNIEE
LGDLRTIGQIVDYLQQLAGGEKKKSEPEFVQQQPPELEHNIPRYTVKLRSLAQPDYLDFT
LPEGHIGLITDDGSLTTYKLTESLIEKGWKVVVISFPQSLIAQQAPLPTGVTRVTLANLS
EEHLQQQLQAIASHCGAIGAFIHLHPMFVGNHTGSISYNESEKAIVKHVFLMAKHLKPSL
NEAAKHGRSCFCTVAHLDGAFGLEYKVNFGAIGAGLFGLTKTLRWEWPKVFTRAIDLSPR
LDAKQSVQNIIAELHDPNLYISEVGYGSQGRVTIIAD
>A0A3N6ISR4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI98-12|TrEMBL
MATARWSLRTHPWLADHAVSGTVIVPGTALVESVIRAGDVLGCGRIEELTLQTPVVLQER
GEAQVQIGVGEPDASGRRPVTVHTRTTGPDGATEDLWTLRAQGTLTEPGAPVVDRPEDFA
AWPPPGATTLAAEGFYELLADRGYEFGPVFQGVRATWSRGDDLFAEVVLPEEVRGDAGRF
GIHPALLDACLHAAHLVPGSAGRTVVPFTWTGVTLHATGSTALRVRVSPAGQDTISVHLT
DPTGVPVAAIDALAVREVTPKTLDPSARAARDWLFRLDWTPVTPPAVVPAVTGWAVLGAP
AAPVTAPDAGRAPLPAFATLGELTEHTAATGHRPGAVLLLAGAATTGAHTPDHDTEPGAP
DAVLDDVLATVQSWLADETTDGTPLVVVTRGAVPTGPGDPAHDLPGAAVWGLVRSAQTQH
PGRLALVDLDIHDSSWLALPAALATGEPQLALREGAAYAPRLVRPSTTEALTVPARTGNW
RLDIPEKGSVDRLDIVAAPGTTEEPAAGQVVIEVRAAGLNFRDVLNTLGMYPGPAVLLGA
EAAGVVTAVGEGVTEFVAGDRVMGLVSGGFAPRAVADARMLAPVPAGWTWTQAASVPVAF
LTAYYGLRDLAHLDAGESVLVHAAAGGVGMAAAQLARHWGAEVYGTAGDHKRTLLRADGW
DDAHLASSRTLAFEDHFRATSGGRGVDVVLHSLAGEFTDASLRLLAPGGRLVDMGRTDVR
DPEQVSRDHPAVALYQAYELREAGEDRIREMFRDLTELFASGALRPLPTVTWDVRHAREA
FRHMAQAKHYGKIVLTLPRAWDPEGTVLVTGGAGVLGGILARHLVTRHGVRHLVLTGRRG
PDTPGAGELAAELRGMGAEVTLAACDAADADALAAVLADVPEDHPLTAVVHAAGVLDDGV
LESLTPGRLRTVLAPKADAARHLHRLTRDHDLADLVLFSAGAGVFGNAGQANYAAANTYL
DALAHRRRADGLPTTSLSWGLWADTSALTGQLDDTDLARVRRSGVLPLSAADGMALFDAA
LAEQRPHLVPVRLDTGRLRASGDEVPHLLRSVYRGPTRRTAAAGAAGTDGLRARLAGRSA
EDRLSTLRDLVAAHAAAVLGHEDTDPLHAGRAFRDLGFDSLTAVELRNRLSAATGLRLPA
TLVFDHPTAAELAAHLDGELSDGTVAASPAAPVPVSTAPGDDEPFAVVGMACRLPGDVRS
PEDLWRLLAEGADAVAPFPDNRGWDLDRLYDAVPEGRGSSRTREGGFLHDAADFDADFFG
ISPREALAMDPQQRLLLETSWETFEHAGIDPRSMRGSRTGVFAGLSSSDYLKRVAHVPDE
IAGYVNNGNANSIVSGRVSYSLGLEGPAVTVDTACSSSLVALHMALQALRRGECTMALAG
GVTVMSSPEIIVDFSRQRGLAADGRCKPFAEAADGTGFSEGVGLILLERLSDARRNGHQV
LALVRGSAVNQDGASNGLSAPNGPAQQRVIRQALADAGIGAAEVDAVEAHGTGTRLGDPI
EAQALLATYGRDRDGGHPLLLGSVKSNLGHTQAAAGVAGVLKMVLALRHRTLPKSLHIDA
PTPHVDWADSGVRLLTESTAWPEPAAPRPRRAAVSSFGISGTNAHVILEEAPAGTPAPGT
AGEPDSTGADAATEAAPAPLPWVLSARSEAALRGQAKALLAHLDAHPGTHPAGIAHSLAT
RRARLEKRAVVVGETTGDLRAGLAALAEGSPAAHVVSGGRGAGRDRRPVLVFPGQGSQWA
GMGAELLDAEPVFAGRLAACEEALAPYVDWSLTAVLRQDEGAPALDRVDVVQPATWAVMV
ALAEVWRAHGLRPAAVLGHSQGEIAAAAVCGALSLADAAKVVALRSQAIARELSGHGGMV
AVSAPHDEVAALLTDLSGVCVAAVNGPSSAVVSGDADGLDTLLAACERQGVRARRVPVDY
ASHSAHVDRLAESLPAALDGIVPRDGDIPFFSTVTADWHPGTGLDASYWHRNLRSTVRLE
ESLRALVEQGHDVFVECGPHPVLTVGIEDTVAATGADAVALGSLRRDDGGPARVLTALAA
ADVEGVPVDWRPAVSHGAPVGLPTYAFQRERYWLEADTAQGDPAGLESAVRLADGGAVLS
GSLSLAAQPWLDAHRTHGAAVVPATALLDWAVRAGDETGLPVIAALDEHIPLLVPDEGRI
EIQLTVSAAADDTGARPFAVHSRTLDADADADDFAVTPWKRNATGVLTDRPAAVAPAAPD
TWPPAEAVATDPAPARTLVEERGLDLTAPFDTVRSLWRAGTTVLADVVLPGTDQADAARF
RLHPALLQSPLALAATTEAATAPLLPAAWRNVTVHATGATRLRLRLTPGDGATWTIDARD
AAGNPVLTGTAVTLPAGPDRLPATTGGDAPHRVAWLPWTDSTPAGNPRPDGPWAVLGDTG
RLAAALRRTGATVQSHADLAALTAALDSGEAAPPALVVTVHGHDTGDDPATAAHTSAHRA
LDLATTWLREPRLTDARLLVVTEGAVATGPDDTVPGLADATAWGLLRSAQTEHPGRFLLA
DLDPATPGGTDEDSAADALLAAAAAAGRTGEHQFAVRAGTVTVPRLVRADHPDGAPAAAT
TAPWGEGTGTGTVLVTGGTGTLGALVARHLVTRHGVRHLLLTGRRGPDAPGAAALRDELA
ALGAETEIVACDAADRDQLAGVLDAVPAEYPLTAVVHAAGVLDDGTLDGLTPDRVDHVLR
PKADAAWHLHELTRDTELTAFVMFSSYAGVAGGPGQANYAAANSFLDALAQHRRARGLAA
HSLAWGFWQERSELTGALGSTGLARLERSGIRPLTADQGLALLDASTLLDTAQLVPVRLD
TRALRADEVPPLLRSLTRPAARRAADAGTEAATGAPSDLRERLAALSGPQQQALLHRTVL
GHVAAVLGHASAASLDAGRGFLDLGMSSLTAVELRNRLNAETGLSLPTTLIFDHPDPAAL
VRHLHTQLGTGGGTPDQPVFAELAALEAAVGGAALDEQDRARLAQRLKALRWKLDATSQD
GGEPEDDSDLDTTTDDEMFDLIDNELGLA
>A0A3N6GT44|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-17|TrEMBL
MCGRVLRAVQNHLNEGDERQEGPGLLILTRGGCLPEGTGTGDAPDPAMAAVWGLVRVAQS
EHPGRIAVADLDGHEASRQAALAAVASGEPQIAIRAGRALVPRLAQLPATAPEHGRTLDT
EGTVLITGGTGTLGGLVARHLAAEHGVRNLLLVSRTGDASEAARTLRAELAEQGARVTLA
ACDAGDRDALAAVLAAIPAAHPLTAVVHAAGVLDDGVVTSLAPERFEPVLRAKADAAWHL
HQLTRDTDLAAFVLFSSASGLLGTPGQANYAAANAFLDALAQHRQAHGLPATSLAWGLWA
QTSGMTRQLGTGELRRGGRGGMDALSSEEGLRLLDAALRSAHAQLMPARLNLAALGDADP
ADLPPLLRGLVRAPRRTARTTAATEGPSLTQRLTALPDAERAEALLDLVRTEAAIALGHD
TATSIEADQAFSGIGFDSLTAVELRNRLTAATGVRLPATLIFDYPTPTALADHLGGRLGT
VPGARPAVLTELDRLEEAFATAGADDELHAHVVARLEALTAKWWSLGGEADELGAEEDDF
DFDSATDDEIFGLIDNELGS
>A0A3N6F3K3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-17|TrEMBL
MDLPTYAFQHDRYWPSAAPVPVAARADGGQDPVDAEFWGVVERGDVDELARTLDLADSGE
SSLASVLPALSNWHRKRSEDSAVAGWRYRVTWQPLADAGTQGTSGATAAQKTPLLNGTWV
LAVPEADAASTALTDCATVLGEHGANVVVLLVDGGRDTVKDVAERLGEAVAEPGTLSGVL
SLLSFDERPHPVHGALPVGSFAVLALLRAMTELGLEAPLWCATRTAVSVRRSDVLARPAQ
AQTWGLGRVASLEHPKLWGGLVDLPERVDATALNRLVSVLARTDHEDQVAVREAGVLTRR
VVPAPLDGPEPARPWKPSGTSIITGGTGALGGHVARWLAGNGAEHVVLTSRSGGKAAGVD
DLVVDIEKSGARVTVAACDVTDRAAVAALLEKLAADGDVVRTVVHAAGVGVLAPLAVTDD
VLFADIASAKVAGARHLDELLGRESLDAVVYFSSVSAIWGVGDHGAYAAANAYTDALAEQ
RRAEGVPALSVAWGPWAGGGMVSDDAKILLDRQGVRLIQPETGMTALRQALENDDTSVVV
ADVDWERFAPVFTMARERPLIGDIPQVRAAVAAPDTGRAEETAEVHTLRAELTVLAEADR
ERLLLDLVREHAATVLGHATPDGVEPGRAFRELGFDSLTAVELRNRLDAATGLRLPATSV
FDHPTPAALASHLQKEILQDTEGDLPPGAELDRLEQVLAARAHDDIGRVRVVMRLESLLS
RLNETHGPGDRTDAAERLESATNEELFDLIDNDLGIS
>F1T732|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
MRKESKCGNEIAIVGLSCMLPQANEADELWDNIVGKKDCIVEISKEKWMESNFFDSNIDS
KNKISSKWIGEVSALKEFDNKFFSISPAEADNMDPDQRALLQETWKCIEDSGISLKTLRE
KRTSVIVGTAEVDTFENQHMPGNEINEFSGKGMFLFMIANRISWYFGFSGESKLVETGCP
SGMCALNDSVNLLKLGKSDFAVVSGINTFKTSHMLKLMSKNGLFSPDGKCKTFSADANGI
VVSEGVVSLLLAPLSVAKENNCHIYGIIENTAVNHSGETFSITAPKLSAQKDLILNAWKG
LKFSPDTINYIETHGTGTSLGDPIEIEALKQAYEKVTDKKNFCWIGSVKPNIGHSLPVSG
LAGIVKVLKMFEHGVIPGQINISEINPLISIEDSPFNITTENVSWQPDEQKLPLRAGVTS
LGFAGVNAHVVLEQYIEVEKESCVSEPSKKYPIVFSAKSEEALIHLLEKWDNKIEKLESN
NSIRDISFTLCSGREQFKYRTACIAEEGSKLIDCIERLKEDIHEVSDNKYLLDISFINED
FVNRIVELVRNNTCFETELLAISKSLNISKKQVYNPEYYPSKHTFDLIMATAYIKGLLSL
ADNFEGIYVETQDNKLLALMIADVINIEDVISYLDNKENAKIIITGKPKIIVNFNNKTLL
TKEVITDKYITCLFAELSLEFKQSDISKTEASLQWLNNIRLLYKNQRTFNKFIHEASKFI
EFDDFDLGEFISAEENNPDDIKDNKLRFMVLVAINIAIKKLYKKWSLIPPNVFADDRVNE
ISELVINGYFTFKEMCELYVKESGKKWQGPFNHTLEDILLIEKSNSITACEKYSIFTGLK
DINTVEKILADIWLKGANIDWKKGLTFKKCKLVSLPTYCFNKKTFKYIKQNIIESESEQD
ELQIKVLDYKPSSLDVMDSYSEKQRLLVFSNIDKSNFEGFDAKELVYVKVSDSKKAQMDE
YSVQPELLEDSFYIFNKLEQMEYVPDVILVALNDSEEIRKTKDYVLSTFIFAANLAKCLI
QKNKFSGKLLFSSMGNESGMYSEGLTAFFKTLHIEYENLYFRNIICYEQTTSDFVSVLNK
EINYFSSSEYKVTYRKLQRTVQTYTDYQPETQIPYLKENGTYILLGGFGEIGKVIAKHLT
EQANVNLILCGRKPENDKVREFINPLNQGSTRVIYKSVDISIKEQLQGLIDNVINEFGYI
TGIFNMTGYIEPGFLESKDNGFLRNGVKLKVDATVFLDEITKDINLDFFVNFSSVSALVG
DFGLSEYVYANCFFDEFISKREKLRKEGRRCGNSISINWPYWQDGGLRMVEKDASRFSLT
TGLSPLLNKDAITAFDSIMKSNVSLQCCVLFGKDKKMNDYLESKLTLPTILQKNINLSLD
NSSDIDVKTIVEQYLTKVIAKELKLNNDDIDLEDGFQSMGIDSILIHKLNRVLSADFSGV
SSTIFFDCKNIDEMVSYFVQTYSEEQLRSILAPENNSIIESKISCECVKPSSIQINKKHL
ESELQTADSAECESKDIAIIGMSGRFPMAKSIEEFWMNLITKKDCVSEIPETRWNVENFY
DNEAKNAYKGKMSSRWGGFIEDVDQFDPMLFQISPLDAGNMDPQERILLEVVYEAFEYAG
YTRKRIQEKVKGNVGVFIGNTTNGYRLLIEDEMVKGNFGTHQALPWSIANRVSYVFELNG
PSFIIDSACSSSLNSIVVAVDNIRNGKCKMAIAGGVNLHIHPSEYVLRSQLRVLSPKGKC
HSFGSEADGYVPGEGIGAIILKPLSDAERDGDNILGIIKGVASNHVGHPNGYTVPSSTSQ
AEVIKTAIDDAGISARDITFIEAHGTGTILGDPIEINGLKSAFSNYTQDNQFCAIGSVKS
NIGHLEGAAGIVSTIKAVLQLMNRVKIPLINCDTPNPRISFDDSQFYLQKELEPWTTYND
KLVLGISSFGAGGSNAHILIQNHEDNRKRLQAREIPQVPVLISAMNDDGVHKYVQKFLHW
LGEQEAENNTLDISDIAYTTQVGRELLDSRICVLCSSVNELKAGLMNFLSNKPCTYVKTH
MTADKITITKSEKNKYAIMAQTAITAGNVEEIAKFAILGIKIDWEQFNRLQKGFIIMLPT
YVFDNHRYWLNFEENSDKDTDFYIKNNKSELAFLIDANISTIENQRFTRTIHSNEFFIKD
HVIDGQAILPGTAIIEMAIEAGNLSLPKHYIKSLEDIHFHKAIEVSEEAVELQIDIIPED
YYIGFKIYICKEDERILSAEGKLIIDNDTDANNIFELPLTENLVQADSEEYYAWLDTLGF
NFKNSFKSIEKLFVSQDLVMSVVSITQTEQFEGRGKNCTLWPPLIDGVLQSTFKLVENHT
EKGCLSLPVSIGKLIMHESTRSNLIALAQKSKNCKEEKGEFIFDIYILNENGKLVMEVQE
YRLVNVKKANHVSKKYEDTDDLIQEVIRRIKSGEIDKNMLLNLKLLE
>A0A4P6Q2N4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomonospora litoralis|TrEMBL
MTDDRTPEEQRLLDYLKRVTRELQQTRSRLHEAESAAAEPVAIVGAGCRLPGGVGSPEEL
WELVAAGGDATSEFPADRGWDVEGLYDPELRRGGTSYVRRGGFLAGAAEFDAGFFGISPR
EALAMDPQQRVVLETAWEAVERAGIDPVSLRGSRTGTYIGVTNSDYLSAAAHWPQEAEGY
VLTGNASSVVSGRLAYALGLCGPAVSVDTACSSSLVALHQAVQALRRGECELALAGGVSV
ASSPGVFIEYSRQGGLSRDGRCRSFGAGAEGTGFGEGAGVVVLERLSVALARGRCVWGVV
RGSAVNQDGASNGLSAPSGAAQERVLRAALADAGVGPEAVGVVEGHGTGTRLGDPIEAQA
VGAVYGAAGSGVVLGSVKANISHVQAAAGVAGLIALVGALGRGEVAPSPGVAGGVSELVD
WRGLGVVAAPEGRSWPVCGGGSRVGGVSSFGISGTNAHAVVEQAPPERSYGFAAGGADPD
REAAPGPRPGPRGDSPFTPDCGAPLPWLVSGRSPEALRDQARRLHEHLGADPGARVDDVG
FSLATTRSRFEHRAAVLGGDRVRNLDALAALARGETPPEAVRGVGGSPGEHTATVFVFPG
QGAQWPEMGARLIEESPLFRDRIMACEQALAPHVDFSLSAVLRGVPGAPPLERVDVLQPA
LWAVMVALAELWSASGVRPDAVVGHSQGEIAAACVSGALSLEDGARVVTARSRLSIPLIE
TGGLLAVPVPAAEAAARIRPWGDRLSVGALNSPESVVISGRRQELEEVLAEYEYEGVKAH
LVASAFASHSAEMEVLRGPIAAELAGLAPRSGSVPFYSTVRGEVVDGAELDAGYWFANLR
SQVLFEPTVRALAEADRCVFVEISPHPVMGPAVARTVESAETPPDAQHRVVATLRRDEGG
PDRFAFAVAEAYTHGCAPDWDALFAQRARSTVHLPTYAFQRSRYWAAPAAGAAPAAGAGT
EHHPLLSAAVSRAGTRGFLLTGELAVHRTPWLADHALGGELLLPGTALAGFALRGGDHAG
CPHLVELAMYTPLRLPETGAVQVQIRVDDPGEDGRRAVTVHSRPRPAADAGPALDDPWTV
HAEGVLAPDDAPGTAWVTSITPTDPWPPPGSEPLPVDGAYADLEKRGYSYGPAFRGLQAA
WRHDGRLYAEVALPAERGGEAAACGIHPVLLDAALHAVLLDDAADDAAEPAPRLPFSWEG
VRLHAEGATALRVCLTPLDEQTFAVEAADPRGAPVLTVEALTSRPLAAAAGGGGDHQPLY
RVDWIPAAAEGTGPAGWATLGTPFSGARPDGVDAHYADLAELRAAVDAGAPVPEVVLYRA
GPACAEPAAAHAAVGDVLALVHGWLADDRFAPARLAVVTAGAVAVDTAPAAESASPESHG
RVSGVPTAGAAEPDLAGAALWGLLRSAQSEHPGRFALVDAEWEADAAHGADMRPLAAALA
AEEDQVALRGGAGYVPRLAVAESARVLPPGREPWRLEPAGDGTVRLNAVANPAATRPLGE
GEVRVAVRSAGLNFLDVMLCLGIFPAEYEFGTECAGVVAETGPGVTDLAPGDRVMGIMHG
AFGTVGVADRRTLAAVPDHWSDTRAAAAPIAYLTAYYALVDLAGVRPGERVLIHAAAGGV
GQAALQLARHLGAEVLTTAGRGKWPVLRSCGVDDTRIADSRALEYEDAFGGDGGVDVVLN
SLTGAHIDASLRLLAPGGRFIEIGKSEVRDAAATAADHPGTTYRAFQLGEAGPERIQEMF
GEILRLFERGALAHLPAAAWPMGRAHEAFRFLQQGRNIGKLVLEPPAALDPSGTVLVTGG
TGRLGALTARHLVRDHGAGRLLLLSRRGWDAPGARELAAELRGLGAEVDIAACDATDRAA
LAEVVAGVPADRPLTAVVHAAGVLDDAPVIGLTAERAAPVLAAKADAAWNLHELTRELPL
AAFVLCSSGAGVLGAAGQAAYAAANTYLDALAVHRRSRGLPATSLSWGLWADRSELSAGL
GEADIARMRRQGLAGALETDRALESLDAALATGEAHLVPVPLDVAGLRARARTSGEVAPL
FRGLVRPPRRSAAAADGGTGGPSGELPRDFASRSAAERTQILLDVVCGHAAGVLGHSDPT
LVGAERNFLESGLDSLTAVELRNRLASAVGARLPVGAVLSSTTPRELAADLRRLLDGTAQ
APGNGSEPGRNAEPPGSSGGGDDSIVELFRHACSVDRAEDGLRMLRAAARLRPRFDEDRC
PKPPPSLLMGEGAVPRLLCLPSLVMVSGPHEYARFAAALRGMCEVHVLPHIGFAGGEELP
GSVRAAAEVQVAAVEEVCGAEPGVLVGRSSGGWVAHAVAELLDQRGRRPAGLVLLDTPLP
EDAALIPLIGGGIIERDRELGLTDAARATAMGGYLDLFDGWSPRPTTAPTALVRPQDPVT
DSDGAPMADALWRFAWPLPHDALQVPGDHLTMLEDHAEPTAAAVGEWVRGLSRRGQ
>A0A1U1BHL1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus subsp. massiliense|TrEMBL
MDSAENPIESTPRFAIIGYAARFPGAADAEEFWDVLREGRDAISEVPADRWDAEEFFDPE
PGAPGKVVTRRAGFVEDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGIAPTD
LAETNSGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQGPSVAV
DTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSHAHMLAPDGKCKTFDA
AADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
DALKRAGVAPSEVGYLEAHGTGTSLGDPIEAQAAGAAYGIGRETNDPLLIGSAKTNIGHL
EAAAGIAGVIKVILSLENELLPQHRNFQNPSPHIPWDRLPVEVVREARPWGRNGRPRIAG
VSSFGFAGTNAHVILEEAPVVSRDAVEPPAPAGGRKFSILPLSARTPAALAQLADKYRAW
LNAHPEAALADLCFTAGVGRAHLEHRAALVVNTREAAVELLSAVADDRPAPGLGRGESHD
TPKTAWLFTGQGSQYPGMARELFETEPVFSDTLNRCAAAVADVLEKPLLDVIFDVDGPEA
EETLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAEVFSLEDGARL
IAERGRLFGSLPAGGRMAAVFTDAERVERLTDEFPSLSVAAYNGANTVLSGPAQDLEKAI
AALVADGVRCDFLETSHAFHSALLDPILDEFEAYANQFNYKTPQRILIDNRTGTALGRSV
KLDGAYWRRHARQPVEFAKSVRTLADMNCKVLLEIGPQPVLTAAALRAWPDPATAPRAIA
SLRRNTADHRQITEAAADAYVLGHLPDFGAFQHAPARKLDLPTYPFERRQYWFSDKRDGD
NRDAGNRQQNNGGPRTEAVRLLEDGKIEELANLLGGVDGDQQTLNVLTKLAAQHNLQRTT
QTIADDRYQFRWEKSPTPLSGSQAAGGVTWLLVADAAGAAQPLLDVLTARGQQHRVLALP
VSDADEAELVEALRSAADEDSALRIVHVAALAGQGSSSTQSLLRIQHQVLGGTRRLFRAA
AAAELRAPIWIVTRGAQHVIEGDTVAPEQSALWGFGRAAALELPQVWGGLADLSDAGTDE
WAQFIGRVSVSGEASTREDQLALRGQAVHVPRLVRREELPSGKPLEVRSDATYLVTGGLG
SIGLEIAGYLAGRGAKHLVLTSRREPGEAARQRIDALAAQGCEVRAVTADVADGHDVARL
LAGIEAELPPLAGIVHAAGEIGTTPLSDLEDAEVDRVFAGKVWGAWHLSEAAAGLKLDFF
INTSSIAAVWGGYGQTAYSAANAFLDGLAWRLREQGIAGTSVNFGPWSAGMADAESRARL
EQRGIKTLSPTDALAGLADVVAASGSNAVQGVIARIDWARFLPLYQQAGKRGFLAELDRE
VPSHLAGVAGAQSGSTQLVERLANAPVQQRKKLLTDYLRDAVAEVTRVDVSEIREDAGFF
DLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLGDVLGLAEQAKPAAQLA
SAVTDRTDEPIAIVAVSCRFPGATDPEAFWDVLSGGVDAIREVPEDRFDIDEFYDPDPEV
AGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYSPAALRG
SRTGIFAGVGANEYAHLLSSESIDKIEPYFITGNALNAISGRVAFALGFEGPAVAVDTAC
SSALVAVHQAVQALHSGDCDLALAGGVNVLLSPVTVIAASRARMLSPVGRCKTFDASADG
YVRSEGCGILVLKRLSDAERDGDRVLAVIPGSAVNQDGASSGLTVPNGGAQQRLIGSVLA
RAGLVGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGGSRDADRPLLMGSVKSNIGHTESAS
GAAGLIKVVLSLQNGVLPQSLHFDNPSPHIPWESLPVRVVDKAIPWQANGRPRRAGVSSF
GFTGTNAHVLIEEAPQPQATPDEDDASTPQSAPVSVLPLSARSPEALAAVAQRYESWLAA
HPDVDLEDVCLTAGRGRSHFEHRAALVVDSIQTAREGLLELAQNRLRPGVVRGEHTNHPT
TAWLFTGQGSQYPGMARELFDAEPVFAETVTRCAEAVKDIVTRPLLEVMFATDRETGGKA
GEALRHTSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSLEDGARL
IAERGRLFGGLPAGGRMVAVFSDAKHVEQIAGEFPRVSVGAYNGPNTVLSGPGEDLEQAV
ARFQEEGIRCTWLETSHAFHSELLDPILDEFESYAAQVQFAAPTLPLVCNRTGAVLTAQT
PIDGQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAPPRAIV
SLRKGVEDRRQIADALASAYVSGHRPNFAALQRHPRRTVELPTYPFQRRRFWPKSSGTAI
EGGGGLPSGILGRGEDLASGDSVYISRLSVRSQPWLSDHVIYGTVVVPGATYAAMALAAV
GTPARAKDVFFYEPIILPEKSSREVQLTLHPLEDGSGSKFQVHSRPYGERDVDWSLNAEG
TVVTGIGDDAEPAPEAAEPAEPVDAAIERMERMRPMELFEIFADLELAWGPTWSGSLKSL
WLGEGEAIGDVLVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLR
YGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYLDRDGRHLGGIREFTVKRAPREAL
LRGLGGDATRLLYTLGWHEVAVPPVADEGEESAASIGTWLIAGFDELAAKVPGCIPLNRE
TDPELLGEVLVAAKERGVPFSGVVWRAAGPGATESTTESAARLEGEIAHLLSAVHTVQNS
AQNGVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTINEEPALRAKLVDGDGSPE
AVQALARLLVTPVEEPEIAVRQGKLLASRLLPWSRTGHLTVPRGSDYVLAPTERGAIDNL
RITEKEVPAPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGIVTQLGEGVTG
VEVGQRVYGSMQGAFGSRFNVPAQFLAPIPDGISGVEAATIPAAALTVRLSFDWAQLKPG
DKVLIHAASGGVGLAAIQMAQQFGAEVFATASTFKRATLRKLGVKYVYDSRTTDFADQIL
ADTDGAGVDVVLNSLTSEGFIEATLRATAKNGRFAEIAKRDIWTTEQMAQARPDIAYEIV
ALDTVMFQEPDRIRVLLTEVSEGLAKGEWTPLPAEIYPLTEARTAFRRMQQARHIGKIVC
QMPNPLAPRPDRTYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRAPDTDAQRVIGEITE
RSKTRIHVFTADVGAESEVAGLLERIRAELPPLAGVAHLAGVLDDALLGQQSVERFRTTL
APKAFGAEYLDRLTKGDHLDFFIVSSSVSSLFGSPGQSNYATANALLDGLIAQRRAQGLP
ATGINFGPWGQGGMASSEAATANISAQGLIPLDPSAALAALAEVIANGTGQATILKANWQ
RAAKVLGSSRPPILDLVLPSAVGEVTGDSELLKQLMEIPVPQRAGFVTEFLQREVQNFLR
LAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQL
PDADAESAEAPPAVESAEAESGTGPAAASDAVSELKE
>G6FYL5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Fischerella thermalis JSC-11|TrEMBL
MGINEQMKNPKIAIVGMDCFLGGCQGLDTFERSIYEGTQHFITFPSQGSQELNKQKQYLA
NYGFESNFTPLGAYIEDFEIDFSDFQLASEEAEKLKPQELLMLKVADNALKDAKLDQRSR
VAVVIVAATELSLRLINQEAKDAISNQWSISSLWNFPGPLFTLIAEQHSVCKAFEVAKKL
LTIREVDAVVVGAVELAENSASLLTRNQTATVNTGVHTLSYDQNVNGWILGEGAAAVVLK
LHETAQQDGDRIYAVIDALNILKDNSSSQTIPDSKAVTQVCQLAFDMASVKPADIGYLEV
FASGVPQQDESEILGLLQAYRTSDPGLNCAIGSVKANIGHTYAVSGIVSLIKTALCLYHR
YIPGVPHWSTPKMPQAWEGSPFYVAPESRPWFLATGATKRIAAINSMEIDGSYAHLILSE
EATQIQRSSRYLEQMPFYLFAIAANDCPTLLEQLRALEQTIANSSSLSAAASLTFTAYQQ
RQHATYALSILGRNQEELTREIQRALQGVADAFNTGKDWQTPVGSYFTPKPLTNKGNVAF
VYPGAYSSYVGIARNLFRLFPKIYEDPVIQSVYSRVLNIEKLLYPRSLSKLSTKQLEALE
QQLIDDPVAMLESEVGVAGLLSAILKNYFQLQPHSVFGYSLGETSMMLSQGIWAHFHEGS
EDLNSSALFKTQLSGPKNAVRKYWGLTQEQNSEGKEFWSTYILMCPVSRVREALKNEERV
YLTLINTPEEVAIAGDTQACQRIIQTLNCDAFRAPFNHVIHCEAIRSEYDALVKLNTLPI
QNIPNTVFYSAAEYKPITLDSHSVGNNIAKVLIQQLDFPRLVERVWEDGSRIFIEVGAGS
NCSRWISRTLKQKEHITVSLNKRGIDEHTCIVKALAKLLSHRVNMDLSPLYSQVQENTRQ
IQPKLRTITLNGSEFNFTALTKKDQKNFQNPTSDTLIQNNKKQQYKPLDLREFERLNPYF
QQGRIKSLEFVEESPKPDFTTTGEQQKKYQYPPTSSLKKHSYVSKLHVLNLRNDLYQKLS
ENTSQFTKSHANFLQFRQESLLQISLIIQRQLDCLQHIFDKNDVDNEHSARE
>A0A4R8SVB3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides salmoniphilum|TrEMBL
MAKISSHRLPNGTIPVLLSADVVELVAKEASAILTYALEHPHVSPNRIADMLFRTRIARR
YRTLLMVRDRDELLSALQAVADGRDHPSVVRGTEPANAHRIGYVFPGQGGQRPGMGRAFY
EAFAEYRAEADRCSALFEANFGQSPLNYLLNADTPADDSASVVQPALFTQMVGLAALWRS
VGVIPDVTVGHSQGEIAAAYVSGMMSLADAVTVVGIRAGIVDAFGAGTYAMAVAAADRDT
CEELLARRSGWAEVSVINSPSLAGISGDRETIQDIVESLTARGVFARVIPVQYPAHTSGI
NAIGTEVSQALRARLSTLQFDESEIDCLGATLGAPITADLPIDQYWFWNLRNPVRFDRAI
TAAARSGADTFVELAEHPALQLAIQENLRVAELPGRVVGTSTREGDRLDEFTLNLAQLMV
HDLGYQWELLQQNTTGRTPLPLLDFPNVQTNDITLWLPYNISYAPTAPTAIPNQVSPSIA
APETDKAAVPARLLKEDWVRLTKRTLTPPRAFGIVDHTGECAELAAAMCSAADDTGSTAR
IIDPGNSIAEFEAIVVLLPERPLPTDPESVSEVTSFFGQHTWWPGRDSAVTDYWLVTVGG
EAVVAHDPPPHPVHAAASAGFRSIGAEYPGIGFRHLDLTSESAQSDSAKTVVMALHTAGE
PELALRGGTLYAKRAIECDTPAPDSVSREHVLVVGGTGKLGLEFCEYFSQRGARRVTLVS
RSGETASVTERLSDIRRKTSTDINVVSCDISDEAAVARLAELSGETPADLIIHAAVDYSD
IEFAAVTNEKVDAVLQAKILGISHVLRAFPRTDSCRIVLCSSMAATIAGRGQTVYAAANR
MLDAMAHRLRSEGLDCVSVQWGQWAVHFELGESGAARLAATGVHPMRPAEALALGMSRLQ
NNAIVVAFDVAQARSVFSLYGYGPLLSGLQAHTGLDRPDTPERETSPPSGDVRTRMIRLL
SDVIGNDRMDTIDTTVPMVALGVDSLQALEFRRRVIEEFHYEVEVADLLGGASVDDVIAS
IDRATPSAVPQTTGGSSPTAKQAKPLTLAETARQAAERAVPQNLDIDRMRSARRDLDLFG
MHATFRLVEPVLREGAALSADDIAEQLGFAPRHGWLLRRWLEVLTEHGHLSYDSGHGYRV
NTPIPSPSCADIYTVCADLGYPRELAEFMGNCNERLADLGQDRVSIQELLFRNGDMVTVE
AAHRDNLASRYVNLAAREVVTDIVSRLHGDRSPVRILELGAGTGSTTGNVVAGLNELSAQ
WDYHFTDVSRFFLNAAQGKFGKYPQIRFGLVDMNIDLVGQSYDIVIAENSLHNALDIGQT
LLRLYDAVNPGGVIVLIESCKANYQVLNSVKFLMSAAPGQPHPGESDIRHGARIFLSENE
WNDQLSRAGFRPLLTLPEAGHPTHMLDQRIIVAERN
>A0A1Q2ZR68|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MQEWRGVVLGGGAEVLAEGEVARRGEVVWLFSGQGSQVVGMGAGLYERFPVFAEAFDEVC
DLLGGSLRETVFRGPQELLDRTEWAQVGLFAVQVALARLWESVGVKPDVVIGHSVGEIAA
AYVAGVFDLADACRVVGARARLMGALPEGGAMCAIEATRGEVEEAGVSIAAVNSGDSTVI
SGSVGEVERVAAMWRERGRRVKRLQVSHAFHSALMEPMLDDFAEVLGGVAFKEPSLPLLS
NVSGTLAGAEIATPEYWVRHVRQPVLFQPAIAEVADRAGVFVEIGPGPVLITAAQHTLTT
EPVLTASLAEGWPDDVAFMQAMGRLYTAGYSVDWSVFFPTDPAPQIVDLPTYPFQRQRFW
LADLKEPEVAAQADEVGFWAAVEGGDVEALCDTLHLKNDVQRSALGTVFPVLAEWRRERS
ERQVVDGWRYRVDWRRVELSASDAPGAWVVVAPDREGWTRVVVQELEAAGGAVTVVGVGS
DRAETAALLRSVSGDGPPLAGVLSLLALAPGGGASSTLTLLHGLLDSGLDTSLWCVTRGA
VSCGGADPVVSPAQAAVWGLGRVAALEHPQLWGGLVDLPSRAEVLDSGALYGVLCGGGGE
DQVALREGGVFGRRLVAESPGDELSDDWQPAGPVLVTGMVAPLVDHVTRWLDEIGAEPVV
EADVPVRTVVHTSLPGALAPLAEVTPQALGEAVAAALTLGERSAETVLFFSSAAATLGGS
GHGVYAAANACLDALAQRHEGPRTVSVGWGVWDLPDATDATDATDAPDVTTPASLSRRQG
LPPLSPHLALKALRTALAGPPGHTLVADIEWERLTPLFTLARPTRLFDAIPAAVSVLEAS
PENTETSSALRRDLAALPARDRVGVLLDLVRTQVAGVLRYEPGRTVRAERAFKDLGFDSL
VAVELRNRLRAATGLRLPATLVYDHPTPRALAEHLLERVMPDGALPPVTRLDEVAAALDG
LPPDDPRRRELVRRLRALLRKESDAAEPDGRSEPDDLSDADADHMFALIDREWGAR
>Q3MCQ4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Trichormus variabilis (strain ATCC 29413 / PCC 7937)|TrEMBL
MQLNNYSQNLESPNSENFIYRDIEIAILSSLTVDDCVVIEKQTKNLESELVAYIVPSGLF
VPEQLLSHLQAILPRELVPTAIVTISTIPLTSTGQVDEVTLASLEVIDSDLIYRAQKQLE
SLSAIERVAVVAEPLVTNVPPVHLQDLLGETEAIAFEDSQQNLQATIPRQNVENQETFSS
KNLAISQGEPLPQSENAPKTLKELLQKATQNSTKNIIYIQPDGSEKFQSYREVWQDAQRI
LSGLRKLGLKPQDKVIFQLEDNQDFICGFWACVLGGFVPVPISIAPTYELANSIASKLQN
TWQMLDKPFVLTNAALAPKIDDLSKFLKLENFQFAIIDQLRECEPDLNLYQSQPEDLAIL
FLTSGSTGIPKCVMLNHHNLLSMTTGLILMGHFSSQESVLNWMPLDHVGALVSLSIMAVS
LGCQQIHVPTNLIVQNPLLWLDLIDKHQATISWAPNFAFSLICDALGDSIYGKMGEQYRP
ENNQKHWDLSSMGFVINAGEPIVTKIARNFLKLLRPYGLPTNAIHPAFGMSETSSGITYS
DSFSLESSSDDSLFVELGLPLAGASLRIVDENEQIVTESTIGRLQVQGASVTSGYYQNPQ
ANQEIFTFDGWFNTGDLGFLHQGRLTITGRQKDVIIINGLNYYCHEIEAAVEEIKEVEVS
YTAACAVRQPGIHTDKLAIFFHTAIVDDTSLLTLLKEIRTSVVNKVGINPDYLLPVEPEA
IPKTAIGKIQRSQLSRRFNTGEFKSVIKHVDILLGNANTIPDWFYRQVWQPKNPITFNSS
LNLTNCTLVFLDAFGLGTYLCQILSERNLQYITVSPGEDFRKINHSHYTITPGQAKDYKL
LLKSLATDNITIGQILHLWNYDQYLGEITSIEALEAAQEKGIYSLLFLVQALAKVQGVDS
PIQLLFISSYVQSISSDDPIAYEKSPVLGLLKTIPQELPCLNCRHIDLPFAEVEKTGTYL
LQEMQVSSKEREVAYRNGQRFIPRLEKVDFTSKPKSPISFKHRGTYLITGGLGGIGIEIA
RYLLKHYQARLLLVGRTPLIHHGKEDVITQHQKAYQELSQLGGEVIYEAVDICDLNHLQI
IVEKAQSQWCKNLDGVLHLAGTSHEQMILEETQENLAAILRPKVFGAWTLHQLVKDNKGS
IFINFSSVNGFFGSTAVGAYAAANSFLDGFSHYQNSHSELTSYCLSWSMWHEIGMSQGYQ
LKNLIRTKGFYVMSSSQAISSMLATLQHQQTHLLIGLDGSNQNIQLWQSQAFNLQKLSAY
FTTHSSDDIFKLQHLTVEDRFGNSCNCNLVKLKEIPLTESGAIDKNKLIRQFTGQDTGTH
VAPRNKLEQQIADIWEQVLGRPVFSVHHNFFELGGNSLVGTQVISRLRNTFSIDLSLQSL
FKLPTVAELASNIEVIEILMKNEYAIANDIAEEYEEGCL
>Q3M3U0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Trichormus variabilis (strain ATCC 29413 / PCC 7937)|TrEMBL
MNTNTKLNSSSVVVVSGGGRGITSECIIYLARQYKCRFILLGRSALAAEPEWSIACVDES
ELKKRIMQHLIEQKEKPTPIKVQNIYKKICQSREIYQTLADIKEGGGEAEYLSVDVTDAS
ALKSALAPVAGRLGNITGIIHGAGNLADKLIENKTEQDFETVYNVKIEGLHSLINCVDIS
QLKFIALFSSFVSFYGNVGQSDYSLANEILNKYAYLLQIKYPECHVVSFGWGPWDGGMVT
PQLKQLFAQKNIKLIPLSVGAEILAEELTQDHTKVPQLIIMSQGISVLPKAFSPEKRSYR
LYRRLTLQGNPFVYDHVIGGNAVLPAVCALAWMTNICEQFYPGYHFLSCQKYKVLKGIVF
DDNLANLYCLDLTEVEKSEEEIQLEALIWSETPKGIPLYHYRALINISQKSHAQQALTFE
DFNYYESSLSLDPYQQGILFHNQRFRGIQKILEITPNKLIASCFLPEISPAEQGQFLTQS
FNPYTTDMFFQCLLIWVRQTYGLGSLPLELTALKQFYTLPFNQEFLINLSIEEQSETKVV
ASAIACDTQGKVYLEATNMQVTTSARLNQLFLNNTVAAKNTVCM
>A0A291SIJ6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces malaysiensis|TrEMBL
MSSSQSEQIVEALRASLKDNARLKREYDKAVAATTAPVAIVGMACRLPGGVSTPEELWEL
VAAGGDGISGFPVNRGWDLDNLFHPDPDHPGTSYATEGGFLHDAGEFDAGFFGISPREAV
AMDPQQRIMLELSWEVFERAGIDPTSKRGKDVGVYSGIAFHDYGTGLDEVPEGLEGFILT
GGAGSVLSGRVSYALGLEGPAVTIDTACSSSLVALHLAAQALRAGECSMALAGGVTVMAA
SDAFVGFSRQRGLAPDGRCKAFAASADGTGFSEGAGVLLLERLSDAVSAGHPVLAVVRGS
AVNQDGASNGLTAPNGPSQRRVIRRALSSARLSAADVDVVEAHGTGTALGDPIEAQALLT
TYGRDRDRPLWLGSVKSNIGHTQAAAGAAGVIKMVMALRHGVLPKTLHVDTPTPQVDWSA
GAVELLTSEQPWPETGRARRAAVSGFGISGTNAHVILEEAPAPTQPTEPGPATDSSAETG
PETSPETDPETGLATGPTIRPATASAATDPAPSPPLLGDAPVPLLVSGRGESGLRAQAQR
LLSFLEERPEVALPDLGWSLASGRAALEQRGVVLAADRDGALRGLAALAQNTPAPDVIRG
TGTGTGPATGHIAFVFPGQGSQWQGMAAELLASSPVFAARFAECDDALGRLLDWSVTDVI
QGADGAPSLDRIEILQPALFAVHVSLAAAWAAAGVEPAAVVGHSQGEIAAAYVAGALSLE
DAARIVVLRSALFAEELVGKGAVASVALSPDAVEKRLAAWDERLVIAGRSGPSAVTVAGE
VAALEELVADCKADGIRAQVVGSTVASHCAQVDPLRDRILAMFADIAPRRGHIPFYSTVT
GGVLDTGELDAEYWFRNARHPVNFEGAVHELLADGFGFFVESSAHPVLVTAMQQMFEDAV
AEAVAVGSLRREEGGARRFLASLAEGHVGGLPVHWPTVFAGAEPHRIDLPTYAFQRRHYW
LEPAETTGDAAGLGLESAQHPLLGAVTEFPESGGVLFTSRLSLRTHPWLADHAAAGTVLL
PGAAFVELAVRAGDEVGCGVVEELVIEAPLTLAEGDGARLQVFVGEAGDSGRRTLSVRSR
PEGSGPGAAWTRHATGVLAPAAVTTAPDTGLAQWPPAGAVPVDPERVAETYEDMAAAGYG
YGPAFRGLRAVWTRGEEVFAEVALAEDQGLSADGFGLHPVLLDSAMHAIAFRGSGAAEAT
LALPFAYRDVALHAAGASALRVRITPNGPEEVALQLVDTGGAAVAAVGSVVSRPVATELL
DTGTSPTRERMFRVGWDELPAPAADITPDTPHPVPVATAEDIRELAETADLGVPEALLLD
LTGDGQEPSASGVREATGRVLELLRTWLAAPELEDTRLLVLTHGAVAVHHDRELTDPAAA
AVCGLLRSAQAENPGRITLADTDRNQASLALLPSVFTGGEPQLALRDGIRYARRLTRANT
TDALALPAGAAAWRLEPGTDGTLEGLALRPAPAALEPLAAGQVRIEVRAAGLNFLDVLVA
LDMNRVDATIGNEGSGVVTEIGPGVAGLTVGDRVMGLFPDAVGPVAVADHRTVVRIPHGW
SFQQAATVPMAFLTAYYGLRDLAGLRSGESVLIHAAAGGVGMAAAQLARHWGAEVFATAA
PAKWDAVRATGIGEHRLGNSRTLDFEPRFLDATRGRGVDVVLDSLAGEFVDASLRLLPRG
GRFLEMGKTDPRSPEEVAATHPGVSYQAFSLYEAGNDRIGEMLRELVELFDRGALHPLPL
NTWDVRHARAAFRYMSQGRHIGKNVFTLPRTLDTDGTVLVTGGTGSLGRLVARRMVTEHG
MRHLVLAGRRGRAAAGIPELEEELGALGATVHTVACDLADRDAVAALLGSIPQDAPLTAV
VHTAGLLDDGVITTLTPERLDAVFRPKVDAVLNLHELTRDLDLAAFVLFSSGAGTFDSPG
QGNYSAANAFLDALARHRHTSGLPATSLAWGLWGQVTDMSAHLDDSDQRRMAKGGMLGLS
VPEGMELFDTALRGPDTVLVPAHMDFAALRALAGSGSLPALLRALVRTPRRAVDNAAADT
DDLVSRLARATTGQQEKILLDMVQQEAAAVLGHASADLIEPNQPFKDIGFDSLTAVELRN
RLSRRAGVRLPATLIFDHPAPAPLARHLLGQLGQEVDTSEALMAELDTMAATLAEAAPDA
TTHATVLARLQLLVEQWETTAGATTTDEEEFDVDTATDEAMFELIDREFGTS
>A0A157SWJ2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Bordetella ansorpii|TrEMBL
MAKRVAVVGLSFRFPSTDTQKYWNDLLEGKDLVTQVEAGRWSHDAYLHPAKDHPGTSYTF
SAGSIGDVSRFDADFFGISPREAALMDPQQRLLLELCWEAIENAGIRPSALRGSDCGVYI
GIASADYSYRLAEDFNALDSSFATGNTASIAANRLSYVFDLHGPSMAVDTACSSSLVAFH
QACRAIVNGEISQAIAGGVSLHLHPYGFITFSKASMLSPNGRCRVFDAEGDGYVRSEGGG
LFLLKDYEQAVADGDSILAVVAGTAVNTDGRKSGLTVPNADAQVTLMRQVYDRAGIDPAD
IDYIEAHGTGTAVGDPIETRAIGMALGRARGQGSPLPIGSVKSNLGHLEAASGVAGLVKA
IYALRHRVVPATIGIRKLNPNIQFDDWNIEVVTRTRKLRNTGILTVGVNSFGFGGANAHA
ILQTPPKPEAMPAAQLAGTTAIPVIISGRTAAALNDAARGMAAALRAHPPRTLYDVAYSA
AKRRDWHQERAVVYGNDAEAIACLLEQFAAGEAPKHHVSAGQRIVNALGPVFVYSGNGSQ
WAGMGRRLMGDHLFAEAIAEIDTLFHKLAGWSLADELRRNDGPNTYQRTEIAQPALFAVQ
VGITRMLAQRGIQPVAVVGHSVGEVAAAWASGALTLADAITVIFHRSSLQGMTKGIGRMA
AIGVDGVAAAALISELELDDLLCVAGSNSQRGATLAGDADALAALGEVLTTRSVFYRQLD
LDYAFHSSAMDSLEAPLLEVLGDIRPAKSNVPFYSAVTGGLLDGTQLNASYWWNNIRQPV
LFEQAMTALTAQGFNLYTEIGPHPVLRSYVNDALKARALTGRVAITSTRGDDEPARVRDA
AGQMLISGATVDWSFLFPWAGRHMALPTYPWQREHHWHPVTAESLGQLTRSRIHELLGYR
SPQNADTWENQLDTKALTWLGDHVVGDATVFPGSGFGEIALAAALQWEPGQFADVEEIEI
QQPLLLDSASKLMRLTLDSSDGRFSIRGKDVGSTDPWIDHASGRVLRNAGALLLNESVPT
LPGRAPDFSGDDHVALTRAAGLEYGPAFQAILHGWLEAPGIVHAILRPNASLEDSLAGSL
LHPALLDCTFQLIIHMLKDDAALGQGVAFVPAKIGRLSWRAGTGVPHQVRARLISRAPHS
LTAEFSLFDAEGRQIAMIREARFRSVRLSKAAVDHLNFLDYVGVPCPHPRMQAQAHPALG
VNALDAALRDVVLDAAANGLHDRYVNEVDPLLESLCDRYAALALHKLSKGGRLTTSTLNA
CREAAPQCAPLLAWVMIRAERAGYLTPMGTAGWQVGITQDDEPSVADIWNSLLREYPDFF
LIVHAAGRIGLHLPALLSGAKQFADVCPRDANSAALALQILGDNTRQKIGTALRECIAQA
QSSRMVGQRIAVLEIGGFQPLFGQDICAGLDFAACDYMYASPSKAALDHASRLQERYPDA
QTRLIDGTQPAEACADVVILHCDVDSPEALQLALQHAQTHLKPEGTLLMRGNHPASWLDF
IFGADISWWVTDLDNTRTSVQYPVAYWQALLIQHGFHCEPLREFVPGSSSGPYLFIGSRK
APQHEAIPTAADGGWLLLAGDHPSGSRELACDLAAGFTERGIPVLVPENCGPDTLDAILL
QALPRLGRIQGIVHLDGLALSSTPAQDPRQSLETQVRRCALAASLAQACERHHLAATLWL
VTAGGAPFLADRVASADSHAALNDASLWNYGRTMANEAAGFSVRLIDLPQAGALPTEALI
QELLAPDAEQEIALDSDGARHAPRLRALTPPRALALPQSSARTPGALRLGFDFPGQLRNL
RWSEYDPPALRDDQLEISIQATGLNFRDVMYALGMLSDEAIENGFAGPTLGLEFAGIVKQ
VGSAVSGYQPGDPVVGFGPASFGNRVLTRADAIARIPDGMSFEAAATIPSTFFTIYYAMH
HLARLEEGESVLIHGAAGGVGIAAIQYAQWRGAEIYATAGSDEKRDFLRLMGVRNIYDSR
SLSYADEILAHTGGRGVDVVLNSLAGEAINRNLRVLKPFGRFLELGKRDFYENTRIGLRP
FRNNISYFGIDADQLMSERPDLTRRLFAEVMALFHEGVLHPLPYCAFDANNVVDAFRYMQ
QARQIGKIVVTYRNGIHDVRPVATPRPSLALSAQATYLVTGGLSGFGLKTAQWLADKGAR
HLVLLSRSGPTAPATQQAIEGLRTRGVNVHAQACDVTDRDAVAAVLAHARQHMPPLRGVV
HAAMVIDDGLIRSATAGQIRRVLAPKVLGAQHLDDLTRGLPLDFFVFYSSGTTLFGNPGQ
ANYVAANGWLEALARQRRSQGLPATCVRWGAIDDVGYLARNKKIKDALQSRMGGSALSSD
LALRLLEDILLADASDLGVLELDWRALTRFLPSANSPKFAWVARRAGSGDGDDTSSQDIA
QMLATMDDETLHPLLMDMLKSEISEILRVPADKIDSERSIYDMGLDSLMGVELIVALENR
FGIRLPVMTLSESATTSKLASKLIELLRGEQAQHAEQPAIASEIAQVVAQHADEDVPKEA
VEQLTDALMATSNLPKQRMIH
>A0A291SL61|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces malaysiensis|TrEMBL
MADEDKLRDYLKRVLGEAQRSRQRVLELEAEKSQPVAIVGMACRFPGDVASPQDLWRLVS
EGREGVSGFPEGRGWDVEGLFDADPGRAGKSYTDRGGFLHGAGLFDAGFFGISPREALAM
DPQQRLLLEVSWEALERAGIDPGTLKGSDVGVFSGVITQGYGMRGETPPELGGYLATGVV
SSVASGRVSYVFGFEGPSVSVDTACSSSLVAMHLAAQALRQGECSMALAGGATVMANPAT
FVEFSRQRVMSSDGRCKAYSATADGTGWAEGAGVVVLELLSEARRNGHQVLAVIRSSAVN
QDGASNGLTAPNGPSQQRVIRQALASAGLSAADVDVVEGHGTGTVLGDPIEAQALLATYG
QDREPERPLWLGSVKSNLGHTQAAAGVAGVIKMVEALRHGVMPATLHADTPSSQVDWSAG
AVELLTEARDWPDTGRPRRAAVSSFSMSGTNAHLILEHSPEPQAESVPEPVSDVVPLVVS
ARSARSLVGQAQRLASFVGSASDVVLPEVAAGLVSRRAVLSERAVVVAGSRDQALSGLGA
LARGESHFGVVTGGSLGGAVSGRKVLVFPGQGSPWVGMGRELLECSEVFAARVGECAVAL
ERWVDWSLVDVLRGDCPVEFFEREDVRQPASFAVMVGLAAVWESVGVVADAVVGHSGGEV
AAACVSGALSLEDAVRVVAVRSQVISGVLSGRGGMASVGLSEEEAVARLREWDGRVEIGA
VNSPSSVVISGDTEALGQVLDALAADGVSARRMEVDFASHSRQVEAAEEILREAFADIRA
QAPLIPFYSTVTSEWVREAGVLDGGYWYRNLRGQVRFGPAIADLLADGHTVFVESSASPA
LVWLINEIADEANTEVLVSGSLRFGDGGLRRLFTSMADLFVRGIRVDWSGVLAAGADARR
VDLPTYAFEHEHYWLPTMSTTDAASLGLSGADHPLLGAVVAVPETGGVLGTSWLSLRTHP
WLADHAVGDVVLVPGTGLAELVVRAGDEVGCGTLEELVIEMPLVVPAQGGVRVQVAVGGP
EENGTRSVAVYSAREDSGGGTGTDVWTRHAVGTLTAATVPATGFDFTVWPPVGAERVPFD
AAAFYEDLADRGYVYGPAFQGLRGVWRRGEEVFAEVSLPDEQRGEASGYGLHPALLDAAL
HSGFVQPAGPEAGIRVPFAWNGLRLHAAGASELRVRTVPSGPDAVSLQAADGAGGPVLSL
QSLIARPVDVEQLDRMATDDGRDALFEVDWTELPAPAPGAEPLPSWTLVASTEDVTELAG
ATEVPAVAVLQALGGDGEHDALALTVRVLEIVQAWFAAADLAESRLVVLTQGAVPADGEG
DVSDPAGAAVWGLVRAAQAENPDRIVLLDLAADSGLDLAGTGMGSVLTAVLAADEPQVAV
RGTTLSVPRLVPAGKRALQIPEEREWRLSATGGTLDSLALVPEPGAAAPLAAGQVRVGLR
ALGLNFRDVLIALGMYPGAAEVGGEGAGVVLEIGEGVTGLAVGDRVMGLTGVGYGPVAVA
DHRCLVRIPEGWSFQQAATVPVVFLTAYYGLRDLAGLRAGESVLIHAAAGGVGMAATQLA
RHLGARVFGTASPGKWGVLRELGFDDAGIASSRTAEFEGHFLTGTSGAGMDVVLDCLAGE
LVDASLRLLPRGGRFIEMGKTDIRDAGVVASEHPGVAYQAFDVFDAGLDRIQQMLVELVG
LFEAGELTPLPFTAWDVRRAPDAFRYMSQARHVGKIVLSVPEPLDLEGTVVVTGGTGSLG
AVVARHLVGVHGVRHLVLASRRGPDAKGARELVAELGEAGAMVTAVACDVTDRDAVAALL
AAVPAEHPLTGVVHTAGVLDDGVIGTLTPERVESVFAPKVTAVRHLDALTRGMDLSMFAV
FSSAAGVFGSAGQGNYGAANAFLDGWMAKRRAEGLPGIAMAWGLWEQTTGMTAHLSQADQ
ARMSRGGTLPIGLAEGMRLFDGALRMPAALAVPIKLDLRGLRADAAAGRGTPALLRALVH
TGRRQAQAGENGGGLAARLAGLTPQEQEALLLDLVRAQVAIVLGHIAVANVEADKAFKDV
GFDSLTSVELRNRLREATGLKLAATVVFDYPTPLALARHLHDEVDITDDAQSLVNSKIDD
IESLISGSLSNDAKKAGVILRLQKLVAKLNGLGDQKTNSGVAEQLESASADEVLDFISGE
LGIS
>A0A2G8Y582|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii COUG|TrEMBL
MTSDLTQALLSCLEAVTEPDSEDTPNQRTDAEYRFCAVRQDDITFAEFLNRVSVQFEVPI
GPLAAKDYESFSSFVFHICELKKEKQVNVKTSSHHIIHRTNRYSTENEKASISIVGIACR
LPGNAKSPGDFWTVLVEGIDAIVPIPSKRWNHKEFSEGHSERGTIYVKEGGFIDGIEKFD
NGFFKISSSEARRMDPQQRMLLELSHEAFESAGLQAITDDNHKFGVFVGCSSSECLMLVP
EATVALCAAGMLALDSRCRPFDAAANGYGRGEGAVVFLLERQMYSPESRCKQKSLATIRG
HGTNHNGRSVSVTAPSDVAQKKLLEGVLRTASVEPQQVAYLEAHGTGTKLGDTIEFRAIK
SVFSTSRSVDNPLLIGSGKSNVGHLEGCAGAVGLLKALLVLYFREVPPTLHFKKISPLID
DEGFDYQIPTKRLTLAGDRPILAGVSSFGLGGCNAHVIIESVPKDREMDALSLSRRHIWD
HMEFPVFESADDGNSFGGLAMRHNVDLCNSTCNHLRRRSTSSLIGKCTLTPVSARLRRFT
AFSSGDGTPGLRVQQYGTTEGSSKANEPHAITEKQISRWTRDNRKGLYVEVESMKDELER
SFSLEDDNGSVTGSVQTEQTEPDQMANEVVNTVDEEAVQTLVLQTVRQILKEAVSIHRDV
SLKTLGIDSLAAVEFRDSLQESLGISLPASLIFDFPTIDDVCRFLAQKLQSGDGGERRNT
PTNLAQPRPSTSSETCVAVRGMSCRFPGAEDGTTESFWEMLHSDSDCIQEIPTSRFDAAS
IFDTDYDARDKIYVKAAGILRGADMFDNTFFKISEVEVRHLDPRQRILLEVAYDALVDSQ
VLGDQGLAAIDNEIVGVVIGCSGNDWNTFLQQHALSASSFSGPGTSPALLSNRVSYNLSL
RGPSLTVDTACSSSLVAIDIARQLLNASQCNLALVGGVQLLLTADTFIHYCRARMLSPDC
RCKTFDASANGYVRSEGCGVVLLENTHDRQVSKNTTYAWLLGSANNHVGKSASLTAPNGP
AQQAVILASLRSAHLQLTSQIHLIETHGTGTSLGDPIEIGALQAVYGQGTSADTPLVLGA
LKSRIGHTEGAAGIAGFIKLICSLRQRIAPPNLHLKTFNPHIDISTADSSRPFLFPTKAY
PLATLMAGEKTEALLGAVSSFGFG
>A0A2G8Y5A3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii COUG|TrEMBL
MPTVSAAGGEQVSRYSSRVRLDVLDALRDHVILGMPLMPGAAFIDALLAAGRLEHTRIDR
RISSSAVIKLSDVSIFSPLLLPESLGSGVAPGEQGFHPSSLELSVEMKPDGRDHLAEVRS
RRIGTTLAAANEEEYEQSHCRGRLAISAGTSQLPASTGGQLTDLQRRFYSEAAVDVSQLY
ATFAELGWQYGKLFRPIAQLFKTDTEAFAELRLPRPVLPCEEGFIIHPAILDGLFQVAGS
LLLTAEKAPAGSVYVPIGVDELAFIPSTSKRDIVWGRVTFAEADDEAKRRQERVVNCTLY
DEGGRVLLYVSGLRSRLLRTEVLLSGTGAAAESNKLWSVEWRASHQQPVAHHEEPVDHST
NWLIAGVHPAVQSQLEEFFLKTMPGAKVVFCAPSVVATDVRRLLQQEAWNGIIHIGGVTA
SISEMECLSDVLVLLQAVIDWQANESSPRPLPAMFLVTRGACCEATENSGLSHSLAPVHS
GMRGLFRTAKAELEALWNRFVPLHYINIEPSSDKQTVTPEELRQVFSVIQQQGAKAQFIQ
DQLTQEPSKPLFYESESLLRDGELLLPRLVPASLEDCGDGNALAEAMTGTIVITGGLGGI
GLVLAKWLTGQEARAVVLVSRTGTPSAEVQRSEDWHLLQSRRQHQTRIVTASCDVGDREQ
VKLLFRSLRAGSFVCHSTGQVVELPPIRGIFHAAGVLRDCPIQKQDAETLASVFRPKSQG
AWNIHNALEELNMNEGLKVFLMFSSIASLVGNPGQANYAAANSSLDALASYRRCRGLAGH
SIQWGPWIEQGMAAELGERLERAGFRGISNKVGVEVTEAVVSQGTTGDFVVACQEFIWPR
FVMRYRGCLPAIFEEQTRSVTVRMRDERSSRQAAGPEMHQESAFASMAPDELRALIQATV
SGAAKQVLGTAEEPPADAPLQALGIDSLGAVEFRNAVQDAFDIRLSATLLFDYPSVQAVS
DHLWSMVRAKTAIDTSSRGDDQLASAAVLQDAGVSIAVVGMACRLPGSVNDLEAFEEMLL
TFQDCIQEIPPSRFSIEEVYDPDPDAKGKIYVREGGFIDGAELFDNRFFGISDAEAREMD
PRQRISLEVSYEALL
>A0A2P9F1A6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MA5143a|TrEMBL
MERSNEGVNGGAPAETLLDVLLGAAREVPGRTVVHVRADGGEHTVTFAGLRDEALRVAGG
LIEAGVTAGTPLPLVADRGEDFQPMFWGALAAGAVPVPLAPEPRRVGPVWELLGRPPVVV
DASTAALLGELDTAVAALPLDALREGRAPRRPHRPAPGDVAFLQFSSGSTGSPRGVELTH
AGVLANLRQIRTAMAITGDDVIATWMPYFHDMGLIGTHLVPMAARVRQIRVEPLSFAKRP
ALWLEAAARHRATLLSAANFALDLAVRRIPAATLAGLDLSAVRLLLVGAEPIAPRVWRAF
QAHTAPAGLDPCAPLPVYGLAEATLAVTVPPLGERAEPVVLDRAALSRGRAVETAPGPDA
VELMDLGLPVQGCEVRITGPVGDGLDDDGGAGNPAGARAARGVLGESRVGQVEVRGPQVG
RGYHRAPGASAEAFGDDGWLRTGDLGFLRGGRLVVTGRHKDVVFVNGRTFHASDLEEAVA
ATPGLPSGTTAAVVGSTDPDGGGERVVAFVRWARPPATTAAPVLRAAAGRLREVLGHDDV
RVLPLPPAAFPRTTSGKLRRGALRERFEAGGFAAVEERWGDAATGRAGALGEHGGGGEAG
RGADSAAGAPRSVRDVREAVRRAWAGVLERPEGEIGLHDRFFDLGGSSLKAMAVLAELED
TFTVTVEPKTLRDHDTVAGLAGYLVEAVAEAGPAATEAGRGAEARPAVTEARPAAEAGPA
AEAGPAAEAGRVAEAGRAAEAAAASAAAVPRGRPGRSRGDAVYSGAVAVLSVACRFPGVG
SPEEFWELLAAGGDTIGAVPEDRWGNGPLPSTRFGSFLPEPAAFDADFFGMDDAEARATD
PQARIFLELAHEALERAGYTGPRRAGRRVGVFAATGDSGYREVLAEAADGDLARHPSALT
GNLPNLIAARVSQVLDLTGPALAVDTACSSALVALHLARRSLAAGECDLAVVGGVNLGLT
GTGHRLLEATGALSPTGRCRAFDADADGFVPGEGGAVLVLARPDEARAADDPVLALVRGT
AVNNDGRSLGLLAPTPRGQREVIARAYAECGVDPAAVSYVEAHGTGTPIGDPVEARSLGQ
AFPPRPDGLPRRLGSVKANLGHLLNAAGMPALVKVVLALTHRRLPPVPHAARPAPFLADT
APGFRLVTEQEPWTTPDGSPLTAGVNAFGFGGTNAHAILEEAPDATGHRDRGSDHREDGG
ADPCGCGAAGCRTCGEAGRPGRARLAGAAPDASGPCLLTLSARTPGALRAAVAELAAHVR
ARPDLAEADVCAAVGTARDDAPYRLAVVADGDLLRRLEAAAHAGDAEPTRARSRTVFVLP
GQGAQRPAAARALYRSAAAFRDTLDEASALVGPVLGRSLTAWCLDEHVAPEALARTEVAQ
PLLVAFGAALSAQLGAWGVRPDAVVGHSVGEITAAHLAGALSLPDALAFAAERGRLIGEL
AAPGAMAAVRGDEDTVAPVVAASVGALCVAAVNSPTQLVIAGTSDAVDRAIATLTARGVA
ARRLRVSHAFHSPLLEPVLDPLGNAAKALAVLPAAVPMLSTVSGQWGPDLSPEYWRAHAA
RPVRFGAAVARLLDEGYDTFVELGPGDTLSGPVRTLASSPGVAYLPALSPALSPAPSVAP
DGGTAGPSGAHSLLETVGRLWTRGTPLSPAAPARVRAGHRRVPVPTYPFQRRRYWPERLD
APPAPHGTPPARDLDGGPVPRPLLWRDAPLLAAPGPRVVRLAGADTALARALADRLTELG
VTVLGPDDSSRGGPDAPETLVWFAEDTTESTTGSATTATTTATADAIASLRGVLALFGTA
PARLLLVTEDAYTTGGGEAPERARPAGALLHGFVLALPDEHPALSSRGVDLSSGDPLTIR
LQSLERELYAAEAADGTPGDTPGSGVGTVAWRASRRLTRTPVASTHAPRTTTDVLPPNGT
YLVTGGAGGLGSALARDLAERGAPDLVLTGRTPTPPRALLAELRALGARARYQAADVSDA
GAIDDLVAGLPPLDGVFHAAGTARPGSLRGKADDEIEETLAAKVHGTVLLAEALRRYGHD
TAVRVAFSSVSSVLPGLSGALGDYAAANAFLDAFTTAEHAAGRPWRTIALGPVSDTGLAS
GPRAEDRLRARGLAPLPVRAALTALRTSLTLDAPHVLVTGTTEPTPTPDLIQSPAPAPAP
APTPVSAPTPTPTPASARGTAPEITALIRRLLTEALHRSPEDIAEDAPFLGLGLDSLSAV
DLARRLERELGRPLPATLLFEYRTIGELAAHLATGAPTAAPPALPAAPPTTGAGRRDDGL
LPLTPLQLAFHTSASLHEGVTAYGYVRQTVSGPLDPALLGRAFAHLALRHPLLRMRLTAD
GGARPRQYTAPAEVSTAHGCGPAWYEIRQVPAGPRALADLEQALCNRPFDLTTEDPVRAV
LVPDQEDAHLTHLLLVVHHAAADGYSLKVLGEDLWSLYTALARGEEAAHELRAASGEFGD
YVAALTAERHSPAFERDQRYWRDRLTTHLSARSTASATPAPALPYDGDPEAPPAPPLVHH
RTEIDEELTSALRAVAARHEVSLFHLLLAAYGRCLARWSGRPEVAVNVARARREVAIAGV
DRLVGPLADTLPVFVTVGPDEPVTALAGRVREIWREAEAHATPGSADLARLLGEMRPATG
PAPRTVAEAGFSLARFPVVHGPDWPVTVTPTAAATATAATRLGLLCWEADASLRLSWNHP
ARLFRPETVRGLADAYVAELRAVAAGLRGPSVAYAPDEQPARPTAEPDERPAGSGQPGIV
ERLCARFRATPEAVAVHTGDSTLTYAALDTASAALATGLRAHGVRPGDLVGLLTEPGGTA
TVTGVVGILRAGAGWVPLDATHPAARHRDQLARTGVRVLVCDPANHEAAARLERVVPVTV
AVAPSPPVATPDGPSPLPDGSAADLVDAAPYDPDAVAYVIFTSGSTGRPKAVPVTHRSMA
NYLDWALATFGYGPGDRLAQTASVCFDASVRQLLAPLLVGASVHTVSRDLLRDPEALLDR
VVADRITVWSSVPTLWERLLTAAEERVRRDGAALPDLSALRWVHVGGEALPAAHVRRWFD
LLDATATPGHARSAPGAPDARRVRHRVANLYGPTEATVNATCHIIDTRPADDVRHLPIGR
PIAGTELVVVDADGRACAPGEAGELLIAGTGLTPGYLGDPRLTAAAFTERDGRRWYRSGD
RVRRTADGVLEFLGRLDDQVKVRGHRVELGEVEAALLAHPGLARAAVLLREGRLVAYVEP
RAGAPEPDAREVRAFLSRTLPPYMLPARIHALAALPLTGTGKIDRNRLAPPPDHDTPAPG
RTARRTPPATPTERLLARAWSQLLDVPEVFREDDFFVLGGDSLTVLELFSRLRDDHRVLP
RPTAVYTHRTLSALAAALDAAHDTAAADALPVAAPDPAAASPTAPVTPYPLTPSQRGFLL
ADALASGDSAWLARFRIRGPLRPELFQRAVDVLVARHPMLRTVFPAGARPPVQQELPDTL
RLPVETEALGEPGLLETRIAEEARRRFEPWAWPLLRLRLFTVAADEHVLVVHAHHLIGDG
YSAALFTRELLTVHDRLAAGPSDGLEPLRSTFRDHVELRATRRRAPSPTPGTATADHLAR
HHAPYTPPVLRASRPPADGTGEPTSLRAPGFHTAGFTLDADRAGALRRLARTAGTTPYAP
FLTAYHRALVVLTGHRDLVLGLAVTGRDDSVPDAHRVFGPFAEAVAVRPPVHGEASGTFV
EDLRRVAAEAVAARTAGPLDLRTDDGLPRTAQFFFTFLDFGALGAPATTLTVLPDDTDTA
LAPPPVGTDVLLAVRPSGDGVRVTVRASASALTEEELAAFADGLRSELEDSAPLDAALIG
YLPAPRDLAAYAGLPPHAVPDRERLRALLFPDGRPRLLETTSTPLGTSGFLTLPVFADEL
TALATPADQSSLAARTARAVEHALALGARSVSLAGVIPALTGYGYDVLREAEPNTTSTAV
STATSAAAPLPGALTTGHATTTVAVVKTVHAALAATGRDLAGLTLAVVGCGSIGTSSLRL
LLARSPRPPARLILCDLPGSAPRLRRLAAELSADRPGTTVRVMESTGTPTGLPAELYEDA
DVVVTAVSGPTALLDVDRLRPGTIVVDDSFPHCFDTARALDRMRRERDVLLVGGGLLALG
ATATRLSADLPPLARTGPARGTRFQPHLPGTLASCRLESLLHAHHDGTELPPIHGLVDLP
HALAHWDAAEAAGVTAAPLHLLDHVIPETTLKALPLPPRP
>F0QDI7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Acidovorax avenae (strain ATCC 19860 / DSM 7227 / CCUG 15838 / JCM 20985 / LMG 2117 / NCPPB 1011)|TrEMBL
MNAPIDSPMISSQAPSGLEIAIVGMAGRFPGAPDVETFWQRIRDGLDSVRTYSDAELEAL
GVPEALRRDPDYVKAGVPLDGFDRFDAEFFGFTPREAEQLDPQQRLFLESAWACLEHAGC
DPARWDGKVGVYGGEGPGVYLMRHLLPAAGLDAGSGIADVLGLMGANAPSSLCARVAYKL
DLRGPAVSVQTACSTSLVAVHMACQSLLGHECDMALAGGVWLNLLQQGGYRYQAGAILSP
DGHCRAFDADAGGTVIGSGVGVVALKRLEDALRDGDTVHAVIKGSAANNDGAAKVGFTAP
GVDGQAEVIRAAQLVAGVSADTIGYVEAHGTGTVLGDPIEMAALTQAFRADTDRRGFCAV
GSVKTNIGHLDAAAGVAGLIKAAMALKHAQLPPSLHCRQPNPRIDFASSPFYVNTEAAPW
PRGAFPRRAGVSSFGIGGTNVHVVLEEAPPPLPRAVRAVDDQAGRGREDAGGVPEPEWEV
LPLSARTEAALHASRAQMATHLRGAAPEALADIAHTLQCGRRAWAWRTAVAAHEPGLAAQ
RLEAPLPAARRVPAAAPEVVFLFPGSGAQHIDMAHGLDRRSAVFRQALDACAAVLLQETG
MDLRALIQPAPGQEAEAAERLARVEWMQPALFAVEYAIAQWWMSCGVRPALMLGHSLGEY
VAACLAGVFTPEDAMRIVIWRSRLMAGLPAGAMTAVPLPEAEIAPLLSLGCDLAAVNGDG
LCVLSGPAAAIDAAEEALRAQGHAPRRLHVAVAMHSRMVEPIVAELERRIAAVPRHAPRI
PFLSNVTGRPITAEEAMSPAYWGRHLRGTVRFHEGLDAVFARPGRVVLEAGPGESMAGLA
RRHAQAATAAGIWASLAHPQQRDRDAQQLAQALAGLWTAGVEIDWPATRGGARRRNVPLP
TYPFQRQRFWVEAGAPRPQDDASAAQPQGLYYLPAWQRSGAVPPAAGPGPGDTVLLLGGA
GLPLAERLARRLAERGARVVKVAAAEGFRDDGGGGFALRPEERADHAALWRALGPVTHAF
HCWGLEEDWEQGYFSLLALVQGREDAGRDGPLSLTIVIDRAEEVAGNEPLEPGRATVAAL
ARVLGQEMPRIACRVVDVLVPNAGSAAEAQLAEALAGEPARPVDEFCVAWRGAQRWVKTY
EPVPAPAACAQRLRQGSVVLVTGGLGSVGLALARHLGRRHGARLVLLGRTPLPPRGEWEG
LLAQADLPAAQRRRLVQLQAMEADGTEWMAVAADVTDAAQWRGALQAVHARFGGVNGVVH
AVMEPGGGMLATRTRAEVEAAFAAKMQGTLVMVDALRGEPVDFVLLCSSVASWVGGLGRS
DYAAANAWLDAFATASRRDSPWPVFSVNWDAWRDVGVGADMDVPEGLGLDERTGMEVFDR
VVNGPLQPQTLVSVTPLAQRLRPLDGLVDALEAAPPPAPSGGTAHPRPVLSTPYRAPEGE
LEDNLAALWTEALGIDGIGADDNLFELGGDSLLAIRLLARVRKAYAVDIHPAAFFKAPRI
ADLAQLVELRLIEDIERGAATSSVSLQAD
>A0A086QNR6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii MAS|TrEMBL
MTPDELHTYVSNVVLDTARQVLGTSELPALDSPLQELGIDSLGAVELRNSLSQRLGVKLS
ATTLFDYPTIRAIIDYIVNQVSGEASAAKATSGALVSAGLAAGRNSPIAVVGYSCRLPQG
SETPDKLWEMLRRAQDCVVEVPLTRFDVDMFYDSDIDAKGKMYVRKACFMDDADMFDNSF
FNISAAEVTYMDPQQRVMLEVAYDAFYSAAYSREHLIGKNYGVWIGCCNSDWHFLEQQSN
PDKSSSYSGPGGSGCLVSNRLSYVFGLKGPSMTIDTACSSSLVAADCGAQAMRFGYCDGA
LIGGVNLMLSPQLFLAFCKARMLSPDCRCATFDEKANGYVRGEGAGAIMLRHLADAQREG
KRILGIVRGTAVNHDGRSASLTAPNGPAQQDVIRSALQIGGVDPLDVALVESHGTGTALG
DPIEMGAIKAVYGAGRSADSPLVVGALKSYIGHLEGSSGIAGILKVLLCLRHHEVPPNLH
FDTPNPHMDLSDFHVVLPKKQMKLQPAQKSSTILGSVSSFGFGGANAHVVFEEYPEPTMA
TDVGGERRSTEAAESAGKKRLAFLFTGQGSQYPNMCKQLYEEEPVFRSHMDACFTVLEGK
LDVKLRDVIYPTAENDVEMLNLLNQTGYSQPAIFCVEYALAQLMISKGFSPSVVMGHSLG
EYAAAAIAGVMDWKDALLLVHERASIMQHIDPNDGVMYACRASEQDAQAAVEKALGEKAV
AVTVSAINGPRSIVLAGTQPDVLAVLKAMDMQSRAKQLTVSHAFHCPLVGEAAALLLPKV
ESVKLSNPNEGITFISTVTGKAVGAGELTKPEYWATHITKPVQFLQGMRAAVTSGEAGIF
IEIGPRPTLVNMGQQCVPRNDYTWVAPVDPKDSNRNSFPQALEKITSNMVCTYTWKRHAF
PWTVVVHPFVDKFVPDQDETKATSQKLLTPAVGELLHDHVVNGTAMMPGVGFLEAMAAGG
FMMVDGKLPSTVVALRDCEFERPMLIPKIDPSTGEFTQAAKLMITVNNKDITLKSIMDGE
EEEIFHSRCTFSLCPATSLPTEPADLLTSLQGRITTPVPITTLYETLQSVGLQYGARFQS
IRECYAAASDEVLAKLRPKLPLHSFERNFRIHPVLLDGALQTAAVLFAEMGHKRPLVPVG
VKRALLARVPAGSEVWSHVVVKSKDLRSATMDVTLFSTKGTILGQLVDVAVRAFDAVAGA
QIPKGLLWEVSWVPKAKAPVEDGVDTVENEASETITPTAKLAVKPTGKVEGLARQPAVNG
QPKWLLLKTPSSMLEGLQKALQGTPSAFVKELDEKHPNNAISSKIHNSEWDAIIYLGALS
AAASSTTCVADALLLANTLGNTAAEKPLPNVLFVTQGQHFIRECGDVPTTAVPTQTGLYG
FCRSAQLELENIIGRPVYLGTLDFAAKDPTLDDPAAFVSALQRVLAEADPTGAAGTCEPH
TVIRGGKEMVPRLVKSSIECRGAVELHMSDRGALSMLKLRPMPKSARVPPPRDCVEIRVR
AVGLNFRDVLNVMGLYPGDPGPPGADCAGTVVAVGEGVEHLRVGDAVFGIAQGALKTFVT
TSAHLVRPLPGRLTFEQAAALPVVASTVEYALHDVAKVKKGDKVLIHAVTGGVGLAAVQF
CKRVGAEIYGTCSGGKKEEFARSVGVKYITSSRDPKKFAEDMCEFLGNGKHKIDVVLNCL
IENYIPETLKFLAPNGRFVELGKRGIWTREQMGTVRPDVLYETVAIDTMMEEDPVWFGGM
LDRIRNLVDGSMLQPLPLHTFEMTDSSEGGVAAFRFLQRAQHIGKVVIRLSSALEVKNFT
TNSRQETENEDSGERHTLSPATAVGKPLSQSVADQMHKTYIITGGTGGLGLVVAQWLIEE
GAHNIVLLSRRGEPPSSVKAGDPVWKYLCGEEQPNCISVATLKCDVSQKDDLLRVFKEIE
SRGLPPVAGIFHAAGVTADAALASQTADSVDQVYLPKAIGAWNLHDACEALGLNKSLEVF
MMFSSVAALLGNFGQANYSAANACLDALAMYRQSLGLCGQSIQWGPWIEQGMAAQLTQHL
EKVGMRGITNELGLRVLGDVMMHPTVAVVGAQSLQWRKFLRRYAFEMPSFFSLVPMAGAG
SSEASVNLATITKEDLCELISSLAQAVSGAAEKPAVDTPLMDLGLDSLGAVEFRNSVADK
VGVKLPQNLMFENPSISSISDYILDKAAGKHGESGVTGANGGSGEGSDIPALDTPLDQWL
MSVLEPAERFALYIDSFASEYGTLQKMAAEEDIITALEDLGVEDGGDFERLHVAWDDLCN
QINTAKRMAAKDIRPSSTAVSVSDHPKPRMPHPMEDVDTLLASLDFDVSTLRPATAPDKV
KNVLLTGVTGFVGRVQLASLMQLKQRPDLRVYCLVRARNADHALSRIREATKEAKCWQET
FVSRIVPVTGDFTQPLLGLSSEEFQELARKIDIVYHTGGDVNLLSNYGRLRATNVLSVKA
IIDLCTTYKVKPLHFASTLGQFPAFFAMFTGHFSGESIREDSTPDVSQMENFYPPSRQGY
PWSKWAAERVLEGARKRGLPVAIYRLPNTYVAYKTGYTNKTDYATALMIASIQEGVFPIG
AATAPLTPVDTICDMLVEASFLEKPKHWVYHLFDPRLVTRADLEQWSQELGISYVGVKVD
EFLEAIKKRGPESPVFKFVPLMQHWRRFWFDPEERTESFPISNEHIFEDLPHMRWPSLRE
VFKNSLLYSVRMGFFPKNSKSIILDPQVALNEARRICGLQLMGREGEDFFLHPWRVLQES
ARRECDLLFGGQLAVYRTVRHYFMNVMYLADAQAKCPEIEKQEIQAPLIIVGLNRTGTTF
LQNLMSTDPSNRSLRYCEMIAPYGPDGNYRPKGLPNTEESWKKDPRIPFAQEILDSQLGL
SEEWMAIHTQRAELPEEDFVIFEHCGRCYSICTEFSVPSYREWLASDNYKETRKAYSFHK
RFLQHLQWQRPAKRWLLKMPFHLFTLEALFETYPDAKIIFMHRDPKETMGSWASLVKHAQ
QSLMDNVDPSALGREELRAMSTMINRALAFRRSHPELGPRFLDVQYQDLVNNPIGVVKSI
YKHFGIPLTLAAQTGIASFCNENRKHRDKLTKHMYSLKDVDLTDGMVQEAFKEYYDSGLC
KYLSSAR
>A0A0H5NUJ2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia farcinica|TrEMBL
MSSYLLPDGTVPVLISSDTADGVRAEAAAVLAYLDEHPRVSPERVAEMLFRTRVARRYRA
LAMVRTREELLDGLRAVVADTPSRVVVTGDGAASARRIGFVFPGQGSQRPGMGRLYYDVS
DAYRAAVDACAAIHRERFEHDQPLHYLLGDEGRYQDTVWEVQPALMFHMYGLAAMWRAAG
VEPAATVGHSQGELAAGAVSAVMTLRDSVLAVTHRARLVERISPRGYSMAVLGMDREECE
ALLARHSGWAELSVVNAPHILAISGDRDTIVDMVELATARGQFAREIKVSYPAHTSIVAE
LREHFMSFLGDEMSGDCFTASEIPCYGATLGAAITPDLTHRDYWYWNLRNRVRFDRAVVA
AVTDGVDTLIEVAEHPVLQLALQENLTLVPREKLPLGRDVKVLGTSLRTAEGLAEFTRNL
ATIAVHDLDYRWDALRTDDGAAPRPPLRDFPHTIMHPRRLWAGPDLPAAEPQPDAAPAPE
RLVETWIPLDKRSMLAPRTLAVVDHTGRCAELADALVAAADRHGATATVLDAAALAGDLP
EFDTAVVLLPELPDTDGAAALDDFAAFFADRAWVPALDRLGPGGQCWLVTTGGESVLADD
PVPHLFHGAVAAGYRSAGIERPDILLRHLDLAAGAGPDQAARIVTAVHTAGECELALRGG
KLYVKRLVVDSATDASAADTDLSHVLIVGGTGQLGLRFCEHFAHAGAGRVTLVSRSGETE
RVAGELNRLRRLGRTEIVVEACDVSDAEAVKRFAATIESAPVSLLIHAAVNYVDAELPDI
TAEMVTEAAGSKVLGLGTVLDIVPFTEQQRILLCSSTAATLSGRGQILYAVTNRMLDILA
RRLRAQGRDAISIEWGLWSVAGPLDEAGFARVADAGVHPMAPGDAITAGLAGPWGDAMIM
SADWAFLREVLDTFGQGSVLPEIATPAAASAPEPDVVEPVVTEQPAAPAAADRPLAERML
TQLHKVMGTDGSESIDGSVPLVALGLDSLQALDFRKRVKAELDRDLPVAAILGGASLDDV
VALMAENTN
>A0A0M6XWW7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Roseibium aggregatum|TrEMBL
MASLTSNIDILGYSTRLPGANDSAEFWSLLKNGECAVTSVSKDRWPLARFGHPVQSTSGK
TYTWAAGQLDDVWGFDPSFFGVSPREAVQMDPQQRLLLQLVWEALEHANIRPSDLAGSNT
GVYVGASSLDYHHRFLVDPAMADMQFMTGNTLSIVSNRISYIYDLRGPSFTVDTACSSSI
VALHEAVSAIESGQIDTAIVCGVSLLLSPFAFVGFSRATMLSPTGLCQAFDANGDGYVRS
EGGAVVVLRAARAGIPEGAKSHGKLLATGINADGRTVGLSLPSPYAQADLLREIYEGLEI
NPTDLAFVEAHGTGTRVGDPAEADALGKVIGQKRDKALPIGSVKTNVGHLEPVSGLVGLL
KSVMALREDLLPQSLHFRNPNPDIPFDELNLKVAGEAVSLERNGTRRLAGVNSFGFGGTN
AHAVIGDPDPETAEASTAPVDAPLVISARSKEALQQLAGKFAERLDNEADETAGNVIASS
AHGRDLLSERLVVLGKTKAEKLDALRSFAESGDENAEVVSGSVIKSNAKVGFVFSGNGSQ
WAGMGQEAYQADTPFRTAFDKVDKIFMGLSGWSLVTTLFAEDLEADLERSEIAQPLLFAI
QVGIVESLRQRGITAAGTAGHSVGEVAAAWCAGALNLEQAVRVIRARSSEQEVVRDLGSM
AALLLPADQAVAAIAESGLPRLELAADNSPRSVTISGDSESLDAFAKFARKKKWAMRRLN
LAYPFHSALVDPIEKPLLAALDGLSPTDVSLPFYSTVTPDERDVRVDAEYWWHNVRQPVR
FAAAMENMAADDFSVLIEIGPKPVLGTYVNDVLRAKGKKAKVLETLKEPSKKAAAAAGNP
LDRIAASVVAHGGQTDLIRFVGERPGHLVPLPSYPWQNSEYRPENSPERVDFMFGQTWPL
LGYRLRQDTAEWFNHIDSGSLPFLQDHKVEESIVYPAAGYIEMSLRAALRWSRSDQIELR
DFDILRPLVIEGDEVWETQVRISPDDHVVEILSRPRLSDNDWSLNARGTFLTPSTTSRTP
WAKPGDSVLSELDHETLYTVTKSFGLNYGPAFRRADKVVKHSNTSATVMLLPQDESLADY
SFSLCPTLVDAGFHGLFALLDGVEDVPQNTSFLPIRLGTLRLLAPETLPASVRIEVTKAS
PRSIEASFEFLDAEGLTIARLTKTRFKAVTLGQDTRPDDLVYRQIATLLPAQDRISPLQE
TFEGLPSLAGNLDLLGADDQELDDSRVLIEALGRTIAHKTLFDLFADRKIELASLVAAGD
LHETAVPLAASLFGWLAESGLCTESDEGFELTDPSGNPDASALLQALTDGGGEHIAEAAL
LARLWTGLSDILKFGLQEASGKEYSSSLFDAYRSSSPGKRALSSALQSGVQSLISSWPSD
QALRVLLVGANGGLAAAIDAALDPTYMALTVTDATSSAVGRGERLWQGSSATEFVEPGEA
SFTFDRHFDIVLFDTSLAEIDADTLKRFTKSMVPGGLVLGAEPLPHPLTDLIMGVGSSWW
DEGATAEFPISRQQADWTKTLEAAGLTEVQTVPLKSTLIEADLLCARAGDRAEEASDTDE
EAPETEAEKKKYLLLTSSEGASHRLAEGLKACLTRKGHTATLLVPGEVTEQLGDDIWSVA
LGDKVDAQVADEALNALVAAHNGRVVHLLGAYAAPADALASVDSRAFSLMTLLKALGPNG
GEFTVLAPAGAQDIAGGKPAAPEQAGIWAFGRVVMNEYPDANLKLIDVSPDLEPGIAAAR
VADEILVANCEREIVLDSKTRSGIRLVKGGVLSSVTLPEGAKPAMRLDILRQGSLDQLSW
HAVERKPLEGKDVEIAVEASGLNFRDVMWALGLLPEEALEDGFAGPTLGMECCGHVVGCG
PDVTRFRPGDKVITFAPACFASHVTVDESGCAPMPSTVSAEEAATIPVTFLTAYYALVHL
AALSEGETVLIHGGAGGVGLAALQIAKWRGAKIIATAGSEDKRNTLKLLGADVVLDSRSL
AFVDAVMEETAGEGVDVVLNSLFGEAMERSIEVLKPFGRFLELGKRDYYGNTRIGLRPFR
QNLTYFGIDADQLLTRQPKLAVDLFVKLVELFEAGTLRPLPHRLFEAADVVDAFRLMQQA
GHIGKIVIRPPAVPENVPTKREISFDGEAVYVVAGGFGGFGATLLHRLADHGAKSLAVLS
RRGASSEDAQEVLAQLTKRGISIKGYACDITSEAAVKKALAEIRAEGHQIKGVFHTAMVL
NDVLIANMDHDGLTKVLAPKVRGAELLDKLTSDDPLDHFVLYSSATTLVGNPGQANYVAA
NGYLEGLARKRRAEGRPGLAVAWGAISDAGYLARNEDVNEMLSRKLGRHALTAKEALDGL
MALMVQPSQEDIGLAALGYARIDWQAARKDLALVGTPLVGLLGLGDEDETGADGAIDLAA
MLEGMDQVTAAQTVAKLLAAEIGKILRIAPEEIDPHKPLSDIGMDSLMALELRMSAERQL
GIDIPLMSLANGATLIDLSSRVANRVLGEENASGISDETQQLASLHVDDQRQETEDLSDI
AAEVENKSRELGSFL
>G4FN28|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Synechococcus sp. WH 8016|TrEMBL
MTNSQPNDIAIIGVSALFPGSKNKDEYWSNIINKVNSITEAGDDWCQNYYDKGSELSNRI
NNNKGGFIGNISHFDPIKYGIMPNSVDGGEPDHFLALKLAYDALNDAGYIQKDFDRRNTG
IILGRGTYINRGYNTLLQHGQIIDQTIEILRKVSPSLDSTLENRIRKELEDSLPPFNAEM
APGLVPNIITGRIANRLDLMGPNYIIDAACASSLVAVDQAIYELNSRRCNMMIAGGVHAS
TPPQINMIFCQLGALSDTTITPFSDHADGTLLSEGLGMVVLKRLQDAKRDNDRIYAIIKG
IGTASDGRGLGLLAPKEEGEILALERAYKNANIDAGTIGLIEAHGTGIPLGDQTEIRSLS
KVLGNIKKIHPTCAVGSIKSMIGHTIPAAGVASLIKTSLSLYYKVLPPTLCESINPELEI
HKTRLYINTETKPWVHSSSLPYPRRAGVNAFGFGGINSHAVLEEYIPSDNSKNSKASSNI
WPFELFLIQGNSWDEVNTKLIVLKKFIDNNPDCQVRNLAFYLSKEPNCSHRISFVTSSYT
DLSQKIEKARMWLISSPINLKKPPKSIFANKIDEIDSNANCFLFPGEGSQYSGIIKDLAI
YFPSIRHWLDILDSMSINERDLLASQVLYPAMGSISGETEDEVKKKLFEMDYSSEIVFIT
SLALYSLLEELGVPCKAMIGHSSGENTALVASGLIPINNENQIVEVMSSLNKIYKNCLKD
EPIATGDLLACGGIQDETLDFLLSEYPNDVFLAMDNCPNQKILYCTNSVSSRVQEYLGIN
GAFIQLLPFNRAYHTPLFNKVATAFQEFYESFEYSRSDKKVFSCYSICEFPDNKESIVNL
AVNQWTNTVNFAKTIELARESGIDTFIEVGPSSNLTNFIKDIFPDNAIAAFATNHRSKNS
LSFFLELLAKLAVRHNLNLSLLFDGREVIDINIEDINPPSNNNGQLLKLNMPIMRLSTDT
AAEFSSTLKHLSKEVITNSTENKTESVQASIDNKVKTKSLSSTNPEQSKSISSNSLQHNQ
EYLSIINEHSKLMNSFLISEQNTMNLVANSLNKNIQNSNLKHDPNELNHHTYPLLGSIVE
ANSSEIVFERTFSIDKDLFLIDHTLGANLSINNKLLVGLPVIPFTISMEIISEAADFACG
GNNKVLEIKGIRGYRWLAIDEDSLTLTVKAKFVSNTNGETSIDAKIYQYNPDSKIGLQLV
FEGIVVCSNSFRNYIPSHAISFLESDLKSSRWSDDELYKTGMFHGPRFQGVKKINGWSNK
GIDATLQVISTSNFFEFTEQPQFRLDSGLIDAAGQLVGYWVSEQFGTDFNVFPFSVKSFS
QFTDILPDESKYGVKAKLNLFQIVKLPLILSLWTNQVMS
>A0A8D3WDP4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces pratensis (strain ATCC 33331 / IAF-45CD)|TrEMBL
MNNEEQLLDYLRRTTADLREARRRLRENEQRAHGPVAIVGVGCRYPGGVTSPEDLWNLVA
TGTDAVSEFPGDRGWDVEALYDPDPDRPGTTYARTGGFLYDAPDFDYDFFGISPREALAM
DPQQRLLLETSFEAFERAGIVPASLRGSRTGVFAGVMYNDYATRLDSVPDDLDGYLANGS
AASIASGRIAYTFGLEGPVVTVDTACSSSLVALHWAVRALQAGECSLALAGGVTVMSTPE
TFVDFSRQRGLAPDGRCKAFSTAADGTGWGEGAGMLLVERLADARRNGHPVLAVVRGTAV
NSDGASSRLTAPNGPSQQRVIRQALAGAGLTAADVDVVEAHGTGTSLGDPIEAQALLATY
GREHPADRPLLLGSVKSNLGHTQAAAGVAGVVKMVMAMRHGEVPPTLHVDAPTDQVDWDA
GAVELALERRPWPDTGAPRRAAVSSFGISGTNAHVVLEQAPPEEEATAPDTETAPAVTAA
ATPVPWIVTGRDPEALAGQIARLREHVTGREDAAPADIALSLATTRTHFEYRAVAVGSDT
GTLLDSLGTATPLTPVGGRTAYLFTGQGAQRPGMGRELRRAYPVYAETFDAVCALADPRL
EHPLAEVVDGDPELLTRTDYAQIAIFATEVALYRLLESWGAVPDHLAGHSVGELAAAHVA
GVLSLPDAVSLVLARGTLMAALPAGGAMAALRATEEEVTPHLDELVGLAAVNGPRSVVVS
GTEAAVDALAARFGGGKRLKVSHAFHSPLMDPMLEAFAEAAARCEYHEPRIPVVSTLTGS
PAGPGELTTPGHWVDHVRHAVRFAPALTTLHDLGVRTFLEVGPDAALTALAAECLPPDSV
CLPVMRRDGDEPHDLVTSVARLHAAGGTVDWAAFHAPHHARNTDLPTYAFRRTRLWLENA
AGGTGDADGLGQQATGHPLLTAATELPDTQGAVLTGRLSLSSHPWLGDHAVHGTVLLPGT
AFVEMALRAAAQTNCDTVGELTLHAPLTLPEQGSVAVQVAVDAERDGRRELTVWSRRTDT
PETPWTRNAAGVLTVAPADAGPPAGPAAWPPAGARPVDLEGLYDRLAGTGYGYGEVFQGL
RAMWRRGEELYAEAALPDGARTTAGAFGLHPALLDAALHVNLLDLPGGQAVLPFAWSGVT
LHRAGTDRLRLSLYPEGNDAVRLDLADGDGAPVATVRGLVARPVTAEQLTADADDPLYRI
DLVPAPGAARTALSDLAVCGADAGLDAPRYPDLAALADAGDVPGTVVLAVPADPGTGEGL
PERARDLVGTTLDTLRLWLDDARFTGRRLAVLLRGDHLTHAPLFGLVRAAAAENPGCFLL
VGTDGSAAPDSALATALASDEPETAVRDGEVRVPRLARAKPGGPHVWDPDGTVLVTGGTG
GLGALIARHLVTGHGVRRLLLAGRRGADAPGAADLRAELAALGAEVTLARCDVADRADLA
ALLGGHPVRAVVHAAGVVDNGVLASLDADRVERVLRPKVDAAWHLHDLTRDADLSAFVLL
SSTAGLLVGGGQANYAAANTFLDGLAAHRRSLGLPGVSLAYGLWASGGGMSAGIEAADLE
RLRRLGLPALAPAQALRMLDAALGAEDALVVPVRVDGAAVRARPDGIPALLRGLVRPAAR
RTGGGPAEGTSSDSWRERLAGLPDTERDRALLDLVRTHVAGVLGHPSPQSVDPGRAFQEM
GFDSLAAVELRNLLAGATGLALPATLVFDQPSPRTLAAHLKTALVPGPADLTRTALADVD
RLEAVLLGLPDEDGSHTRVTARLEALLRGWQDARGGDAAPAPAQDFGEASDAELFATIDN
ELGAL
>D3D449|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. EUN1f|TrEMBL
MSDAERAPQPPIAVVGVGAIMPGSTDAAGFWTSIIRGEDLITTVPPSHWLVDDYYDPDPT
TPDKTYVRRGSFLPTVAFDPTRFGIPPNIIPATDTAQLFALLVADQTLRDALGDRYESAD
RGGIGIILGSGNLELLTEVSTRLGRPTWLRTLRELGYPPEEAERICQRMVRDYPQWQEAT
LPGGLGNIVAGRVANKLDLHAVNYTVDAACASSLAAVSAGVNELVLGRADMIIAGGVDAL
NNPTTFVSFSKTPALSPSEDCRPFSAAADGTLLGEGVGMVALKRLADAQSDGDRIYAVIR
GIGSSSDGQGQAIYAPAIGGQVRAVRAAYADAGYGPDTVELVEAHGTGTPVGDRIEVNAL
SEVFGASGRPDRRWCALGSVKSQIGHTKSAAGAAGLLKVVLALHHRVLPPTIKVGEPNAD
LDLESGPFYLNTVSRPWLRTAAYPRRGSVSSFGFGGINFHIAVEEAPDPVDRPDGGAPGS
PRSTESSRSTESSRSTESSRSTESSRSTESSRSTVSTSTHRSWPGPGSELILFSADTPED
LLRAVRAVEARPPAEVARERAADFDPRHPARLAVVANTAECLTEALDQAANLIAQRPGQS
FTNPRGVHYAAGAPPSARPVFLFPGQGSQFSGMGVDVAVRYPAAKAVWDRFGDLKIGEPA
NGDPVNGSAAGGSAANGSANGSDTLRRIVFPPPAFTAADRAAHRDALTAAAQPAIAAHSL
ALLAVLASYGVGPAAVAGHSFGELTALHAAGVFDADQLIRLAHFRGELMRRTIATTPGRM
LAVSATRDEVISVIDGAGLSEVWLTNHNAPRQVVLSGSGECLEAMRERLAADGVTTRWLD
TATAFHCPLVRAARDPLRRFLDDVPMHPPRIPVHAGLDGRPHPGDPELIRDRIAEQLTSP
VLFLDEIEALYASGARVFVEVGPGSTLTGLVGQILDGREHVAVSLDRPGQDGDASLQSAL
GLLAVHGVPLDLRPVTDAPRPATPTRRPVMTMEIDGANYGHLGMQTGPREAQASASSVTV
PPAGTGNGHRPTRGLSSPAPVTPPQPSPPRRSRRHRRRPWHRGRPRRLRRRWHRPKRWHC
PRRWHRPRARHRPRVWRLRSRWHRRRPWHRRTRDHCRSPFRRLSPWRCPGRRRCPGPSTC
RDRPGRPHSPRCTGGPPRRTPPLRSS
>A0A0L6JMG5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933|TrEMBL
MSKYYYPEDRVAIIAMGGLLPDANKIETLWQNILDKKISIREIPERFYNKNIYYKPEFFG
KSNKFNKTYTNIAAVPDVLDNTALCRKYKIPPAVAEYMDPNQHATVYCVDQVIQEIKSNI
TKERTAVILNTSAPGHNFENVVRRTFLQRVESEFLNHPGLKSNPMLHQIEGVFNEMQEKL
LEGNLNITEDSTTGYLQNLTAGRISNIFDFQGPSFTVDSACASALTAIAISVSGLLNHEY
DLALTGGVEVTLTEVGLVAFSAINALSPDGSYPFDSRANGFVMGLGGGIIALKRLSDAIR
DGDQIYSVISGYGQGSDGKGKYIAAPSADGQVRVIKNAVKMAGYSAETIEMIEAHGTGTS
VGDVSEITALKNAFSDFGVSRKNYCGVGSIKSNIGHLRNAAGVAGVIKASMALYNKFLPP
TANVREVNPNLKIEDSPFYILTEGMNWNEQVSHPRRANVSSFGFGGADYHFCLEEFRGEF
VNKSYSFNDKVCEKSDNVRNDSCECQKEALLLSGNTFYEVKESFERFLSFGESETDFGKA
AYSNNVKAAAKMKIRVAICASTYDELKEKWSMVCQQMDGNKKMDDGLLLAKGIFIGIEEP
VASDTIAFMFPGQASQYPNMLKELYESYPIVKSFYTQVDNIWRANYGYSLMPLIFGDDED
QIFNQLRNTKNTHPAIFLSNMAVYKLLTEAGVKADYMIGHSLGEVTSFYAGEILDLKSAV
YMVGERGYCFDEIDQDKRGQMLSVKANKSDVAAIIKENGLHVRIANMNSHVQTIVGGAAS
EIESFMKLLAQSKITYTLLNVSHAFHTELIKEAAEDFYNKIKDLKFNKPKSKIMACHLKE
FYSDIEDKLQDMAGLLKDQITSPVNFIDSIEKLYDEGVRVFIEAGPSNVLTNLAKNILDN
KDVKVIPVNFKGKNSSESFKQALAALFAIGVDVSMVPTENMFKTSESICRPKEYACETNS
NLLRSVDSITSITNNILSNNDSILYSGVSVGLPGTFKKAFSDDNFDLLFEGTNFIEKLTD
EEQNSILDLNVTRLLKTEEVTEFKKISSINEIIKFAGKFGQMDMIEDYLMDEKMLKQTSL
AVCAGVAAGYEALKDAGIPLVREYIKTASGSLLPGRLVLPEEMRDNTAIIYANGLFPLDN
VITQVSKYTASKFGSEPKMDIINFYSSVISKISDYSSRKLLTDWFNAHYSRLVGKYTEQD
IYEFNYNFMTILSSQANNRFAQLIGATGPNLYVNTACSSTASSVSIAEDMLRTGRAGRAI
VIGADISSTEAVLPWIGAAFLSIGVLSDSHDLFEAAVPFDDRRNGMILGSGAVGLVIEKE
TDIEKRGMKGICRILGTHMFNSAGHNSKVDTKRHCIELDRFLLKMESEHGINRADIASKT
VYCSHETYSPKNGGCGQMEKRSLEYAFGEKFKDIKVINTKGMTGHTMGASLEEAISAKAL
QYQNIPPISNYKVEDPDLSGLNLSKGGSYRFQYVLRGVSAFGGNGNYHLLQKVSDGDDRV
FDKTIYENWIKRIADSNDAKLSSHGRILVAEAANANYVSKKEDLNSKSINMLGIKEEGYH
DSFLESSYRKSLQKSVNNLEESNGSIDNDTLVEHHGCVEEEVLKIYSEITKYPVEMLDTE
MELEADLGIDTVKQATIFSMLSERFGLKYDGSIALSNYPTIGHIVRLINSKTEGENKNDK
VEGKNTVVSIDSGSGDAILDIISEITMYPKEMLESEMEFEADLGIDTIKQATIFSRVGEM
FKIDDPSILNPSRIRTIGSIIQLIESTFGIESEKQSGVNEENKKNYDQLDREDEEQPIAD
NLERQLCIQVPEVVEENINSKDFEIQKKNVLIIGDNEDTVQKATVFFEKYTDNLHCLNFM
YPMDTEDIEKKVKELAWKSIEVIIDLTHIGLNVDVSNLSETDEDKYLTLSSQIRFAFYKS
LSEAVKKPEVRIIAAVAMDGSFGFANKSDVIPDPFYGAICGFYKGLGKEWTECKVKVLDI
GGFGEKVLDNEALAKIIDEIEACGSSLETGYINNKRVVIKLDNLDRADLKNDLQINDGHF
LITGGGNGITAEIIRKLSNEMTGKFTIIGRTSLPSDIDKISKLDASSLEKKKIEIRDALL
EKGIKATPLEVQKEYNKILKSISVYTVMNELKSKNCSVLYINCDVRDGDKLKAAIKSAAN
VHGPVNVVIHAAGVEKSNMLDKKTEEEFNEVFSIKTKGLCNLYRFLDKEQLKVIIGFSSI
SGRFGNEAQLDYCSANNFITSFMSMVGKENKKVQALSIAWSGWKDIGMAWRNEFVKTNSE
ELGIHLIEPDRGAHEFINVLTSRINAAEVVISRGLSSFKDFTVIKESTFKTPFIDWITKK
DKKVDKVYKVLSVKRDPIIKNHLLGETPLMPAVGFMEICAEFHSLLHGRKNQYCFRDITL
TNPLKLHRENSQEISMIPRQLGEEGSYKATFYNYFQPKNMEGRFIELNRMEIYNSSGSYG
DLEYLKNIEDGNMKEFTVRDLLAGQANSIKNGIGFGPLFMDDNCKKFNKAKFNDNSIVYS
ILLSEEQITNKQYNLDNLLINPVFMDSLMQACGIHSAESSGRVHLPWKIQEFGVVNVPRT
LGSYRVYGKLLNENDDMKTYDVIMYNENDDVNYYAKGVIVRRINS
>A0A0N0MS17|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MSSEKVVEALRASLRENERLRKHNQRLRDATTEPVAIVAMACRLPGGADTPEDFWRLLAE
GTDAMTDFPADRGWDLDSLFEYGSATTQGGFVHDADRFDAGFFGISPREALAMDPQQRLL
LEVAWETVERAGIAPAALRGSDTGVFIGCSNQEYGSGLREIPEGVEGHILTGNAGSVVSG
RVAYTLGLEGPAVTVDTACSSSLVALHLAAHALRAGECALALVGGVAVMSTPGAFVEFSR
QGGMAGNGRCKPFADAADGTGWGEGAGLLLLERLSDARRNGHRVLAVVRGSAVNQDGASN
GLTAPNGPSQQRVIRAALASAGLSAADVDAVEAHGTGTTLGDPIEAQALLATYGQDRELP
LWLGSVKSNIGHTQAAAGVAGVMKMVMAMRHGLLPRTLHVDEPSSHVDWSAGEVNLLSEA
RDWPRNAERPRRAGVSSFGISGTNAHVILEEAEETEVSDASEGDGFVVWPVSGRGEGALR
AQARRLLDAVEGVDVPVAGVGLALGLTRSVFEDRAVVVGRGVDELRAGLAALATGESVGS
VVRGAVVRGRTGFVLAGQGSQRLGMGRELYEAYPVFAAAFDAVDAEVPFGLREIVFGDDE
ERLNRTEFAQPALFALEVALFRLLESWGVRPDVLAGHSIGEIAAAHVAGVWSLADACQLV
VARGRLMQALPAGGAMVAVQAAEGEVLPLLNDRVGIAAVNGPQAVVISGATDAVEEIAAR
FRAEGRKVTGLRVSHAFHSPLMEPMLDEFRAVVSELAYGRPQLAVVSTVTGALATAEELM
SPEYWVEHVRRTVRYGDAVHALAEQGVTRFLELGPDGTLSALAQAVLPVAAEGAEAAVVV
PVLRKEGAEAGSLLRAVGVLHAQGHSPDWSALFPGARPVELPTYAFQRERYWLADAVSGA
VTEEERGEAVDSAFWAAVRKGDVGDLAERLALDPDVLAPVLPALTAWHHDSVQRATAESW
QYRETWTPLPSPTGSPAGTWLVPFCAGDEEATATAAAVAEAFGAAGAEARPVPVAADADH
TQVTAALTEAAAARGGTTLQLLSLLGLTETPHPDHPDVPLGLHLGTLLVQALAANGTRAR
LWAATRSAVSVGAADRLTRPVQATTWGLGRTVAVEHSDLWAGLVDLPTRPDRRALARLVA
VVAEPGDENELAVRDSAVFARRLVPGVNHGGTDGRSGGATDGLSELTLTGTTLITGGTGI
IGAHVARRLAREGAAHLLLVSRRGPDAPGAAELQEELGELGARVTVAACDPADRTALDAL
LASVPAELPLTAVLHVAGALDDAPLTAMDPERYATVLRAKLRAAANLDAATRQLATPLGA
FVLFSSIAGALGSAGQAGYAAGNAHLDALARQRRAAGLPATCVAWGPWAGGGMADDPAVL
TRLRRGGLTPMDVEPALTALGRLLAHDDTWALVADVDWARIATGRRGLPGAALLDRIPDA
ARALAATTDDATAGRSGQLHAQLAPLGATDRRHLLLRLVRHSAATALGHPTPEAIQPNRA
FQECGFDSLTAVELRNLLATATGIALPTTLVFDHPTPAALAEHLLRELDDGALPLGTADT
APAPRGAVDDEPIAIVAMACRLPGRITSPEQLWDLLADGGDAVSTFPTDRGWDLDTLYDP
DSLRPGTSYVNEGGFLTGVDGFDAAFFGISPREAVAIDPQHRLLLEVSWETVERAGLDPR
SLRGSRTGLFVGCGHQGYGAGLADVPDDVRGHLLTGSAASLASGRVSYALGLEGPAVTLD
TACSSSLVALHLAAQALRAGECDLALAGGVTVMSTPGVFVEFSRQRGLAGDGRCKAFADG
ADGTGWSEGVGMLLVERLSDARRNGHRVLAVVAGSAVNQDGASNGLTAPNGPSQQRVIRA
ALASAGLSATDVDAVEAHGTGTTLGDPIEAQALLATYGQQRERPLWLGSLKSNVGHTQAA
AGVAGVIKMVLAMQHGLLPRTLHVDTPSSHVDWSAGAVELLTEEREWRPEGDRPRRAAVS
AFGLSGTNAHVVLEEPRDASPGDLPEELPSAGTVPWLVSGRSARALRAQAARLAEHVDAH
PELSPAALGHALLATRTAFEHRAAVVGADREGLLAALRAVGRGEPAPGAAVGTADSEGGL
AFLFAGQGSQRLGMGRELYETFDAFAEAYDTVCAHLDNELGRSLREIVFGDDEQALNRTE
FTQPALFAFEVALFRLLEAWGVRPDVLAGHSIGELAAAYVAGVWSLEDACRLVAARGRLM
QALPEGGAMVAVQAAEIEILPLLTDRVGIAAVNGPRAVVISGDEDDVTVIAAHFTALGRR
TSRLRVSHAFHSPLMEPMLRDFLAVAESLTYHRPQIPIVSDVTGTLADPGELCEAGYWAA
HVRQPVRFAEDVHRLRGQGITRYLELGADGTLTALARTCFADEPTVASGTAPASAPLLVP
ALRKDRPEIPSLYGALAQLHVHGVEVDWSPAFGTAAVVAASAVDLPTYVFQHERYWLDHG
TETVADAARTAADTADDRFWEAVECEDVEALTRALGLGAEQVGAVVPALASWRKRQQEQN
AVDALYYQVVWKPAATEQAVAATDVTDRRWLLLLPGAADSEDRTATTLATALGKALGGPD
RVVTVDVPDGDRTNRAAVAALLREAAADGPVEGVLVLASRAGAEPDGLPLAPAVVAVVLQ
ALGDAEVGGRVWVATRGGVSVGRSDGPVDEAQGAVWGLGRIAALEYPDRWGGLVDLPEVL
DRRATARLTGVLLGGGPEDQVAVRPSGILGRRLERIPNAEEETAGWRPRGTVLVTGGTGA
LGARVARWAAGAGAEHVVLVSRRGLEAPGAGELRDELAGLGARVSVVACDVAERAALARV
LAEHPVDAVVHTAGVLDDGVIDALTPERFAAVLRTKALSALHLDELTRDRDLDAFVLFSS
FAGTVGTTGQGNYAAANAYLDALAERRRAAGLPATSIAWGPWADGGMADEEVVAWRMHRG
GVLPLQPALGILALRRAAGEDRPLVMVSDIRWAEFAPPFTMTRPSPFIEYLPEARAAVEG
AGPASDRFGRGDGSGLRDQLTGLAPVDQERVLLEVVRLCAAGVLGYSGASAVPAERAFRD
LGVDSLTAVELRGTLAMATGVPLAATVVFDYPSPVVLARYLREQLLGAVVEAVVPVAAVG
SAGVGSDPVVIVGMACRFPGGVEDPEGLWRLLSEGRDAVGPFPADRGWDMAALYDPTGER
SGSTLVDVGAFLDGVGHFDAGFFGMSPREALAADPQQRLLLEAVWEALERSGVAPGSLRG
SRTGVFAGTNGQDYAGVLLASDADVEGHVGTGNAASVLSGRVSYVLGLEGPAVTVDTACS
SSLVALHLAAQALRGGECDLALAGGVTVMSTPGAFVEFSRQRGLALDGRCKAFAEGADGT
GWGEGVGVVVVERLSDARRNGHRVLAVVAGSAVNQDGASNGLTAPNGPSQQRVIRAALAS
AGLSAADVDAVEAHGTGTSLGDPIEAQALLAAYGQGRERPLLLGSVKSNIGHTQAAAGVA
GVIKMVLAMQHGVLPQTLHVDEPSSRVDWTAGEVRLLTEAYEWERVAEDRPRRGAVSAFG
VSGTNAHVILEQPIAEEVAAAADAEPTVTPSVVPSAVSSLVPWVVSGRTAAALRAQAGRL
AEFVAGDEGLSTAGVGGSLVRSRSVFEHRAVVWGADRAELLRGLDAVVEGGASVEGAVVG
SVLAGGRTAFLFAGQGSQRLGMGRELYEEYPVFADAFDAVCAHLDGELPRSLREIVFGDD
AELLNRTEFAQPALFALEVALFRLLESWGVRPDVLAGHSIGEIAAAHVAGVWSLADACQL
VVARGRLMQALPAGGAMVAVQATEEEVLPMLNDRVGIAAVNGPRSVVISGAADAVEEIAA
HFRAQDRKATALRVSHAFHSPLMEPMLDEFRAVVAELTYGQPKLPIVSTVTGEAATAEEL
ASPEYWVEHVRRTVRYADAVRGLVGQTVTRFLELGPDGTLTALARDCVADEGLLFAPVLR
KDRPEGGTVLAAVAAAFTRGAEADWSMLFPAVPWVELPTYAFQHENYWPKAVNREAGATP
SGSGGSGGSGSETDARFWAAVEREDLESLAGELELAENVVGAVLPALSSWRRQNVEQAAL
DELRYRVEWHPLSDVPGSATLSGHWLLVEPADRTADAWTQAVIDGLVERGAEVERVTCER
DAGREELAMLIGTLGASASASASASVAGVVSLLALPEESPAEGEVPLAISASVALIQALG
DADVTAPLWVLTRGAVSVGRSDGPTDALQGAVWGLGRVAALEAPGRWGGLVDLPETIDRR
ALGRLAAVLGGLGDEDQVAVRASGVFGRRLSHLPVISGEDNDSWRPRGTVLITGGTGALG
ARVARWAVAEGADHVVLVSRRGLEAPGAGELRDELTASGARVSVVACDVAVRAAVEELLA
EYPVDAVVHAAGAVVNLPLDQVSLGDLGEVWSGKVAGAVNLDAALGDRALDAFVVFSSIA
GVWGSGGQTGYAAANAFLDGLVEARRTRGLAATSVAWGPWADGGMAADAEAVEALRRRGL
LVLEPDRAVRALGRVVPGADALTVVADVDWSRFAPAYTSVRPSVLLSILPEARTALATLS
TPEAEKTAGSALRERLGRLSSAELDRALLELVLGRVGAVLGHRDAEAVEATRSFRDLGFD
SLTAVELRDRLGTETGLHLPSTLVFDHPTPTALVRLLRQELFTEQEQADGHSETTSPNHP
SGSGTSLPVPAAPTTTDDPIVIVGMACRLPGRVAGPDDLWRLVTEGTDAIAEFPTDRGWD
LDALHGRGVGDGDGAGSHARAGGFLYDAGEFDPAFFGISPREALAVDPQQRLLLETSWEA
LEHAAIRPDLLHGSRTGVFVGAGSSGYGAGLREVPEGLGGQLLTGVAGSVVSGRIAYTFG
FEGPAVTVDTACSSSLVALHLAAQSLRSGECELALVGGVTVLADPGAFVEFSSQGGLAAD
GRCKAFSDDADGTGWAEGAGILVVERLSDARRNGHQVLAVVAGSAVNQDGASNGLTAPNG
PAQQRVIRQALAGAGLTPADVDAVEAHGTGTTLGDPIEAQALLATYGQGRQQPLLLGSLK
SNIGHTQAAAGVAGIIKTVLAMHHGLLPRTLHADRPSTHVDWSAGDIRLLTENTEWPHTD
GRPRRAGVSAFGVSGTNAHVILEQPLHDDELADVDTVVPEPLVPWVVSGRSRAALRAQAG
RLAEFVAGEDTLSAVRVAASLVRSRSVFEHRAVVWGADRAELLRGLDAVVEGAASVEGAV
VGSVLAGGRTAFLFAGQGSQRLGMGRELHEEYPVFADAFDAVCAHLDTQLPRPLREIVFG
DDVEPLNRTEFAQPALFALEVALFRLLESWGVRPDVLLGHSIGELAAAHAAGVWTLADAC
KLVAARGRLMQALPPGGAMVSLQAREDEVLPLLDGHVGIAAVNGPLSVVISGAADAVEEV
AAHFRTEGRKTTALRVSHAFHSPLMEPMLAEFRSVAEQLTYGTPRTPLVSALTGELASEA
ELTSPEYWVRHVRDAVRFADGVAALAGQNVTRCLELGPDSTLTTLTQSCLPTADGLEVAV
LRDGHPEPRTLLAAVSALFTRGVDDLDWTAALPSLARAPRVALPTYAFQRRRYWLDVAAG
SGDAPALGLAATGHPLLAAAVPVAGSDAVVLTGRLSLRTHPWLADHRISGTVVVPSTAML
ELAVRAGDEVGCGQVRELALEAPLSVPERGAVRLQVRVEEPDARGTRALTVYSCPADASS
NGAPSDAVWTRHAGGLLAPATVTPEQAGGGADFTVWPPADAEPVEIGGLYERLAADTGLE
YGPVFRALTGVWRHGDDVYAEVALGEGEYERARRFGVHPALLDAALHPLGLGLPEGLGDG
LLLFAWQRATLLADGAAALRVRLTRCAEDAVTLHAADTSGQPVLTVEALRLRPVVTGGGD
TPAERAEREHETAVADDRMDPAPAHSPSPSSQQPARRRAVAGGAGGAGGAGGAGAVGAEG
AGLVDRLAGRSPAERQRVLLDLVRRKVAAVLDYVDVDEVEPSRVFKDLGFASITAVELRN
QLGADIGVLLPATLVFDHPTPLALAAHLDEELFGTRPEFAPPAVTRAGLDDDPVVVVGMA
CRYPGGIAGPEDLWDLVVNKGDGISPLPSDRGWDLAALYHPDPDHPGTCYAREGGFLHNA
SQFDPGFFGISPREALAMDPQQRLLLEASWEALERAGIDPASRRGSLTGVFAGVTYQDYI
GILGAAKDSFEGYIGTGNSPSVLSGRISYALGLEGPALTVDTACSSSLVALHLAAQALRQ
GECDLALAGGVTVMSTPGSLIEFSRQRALAEDGRCKPFAADADGASWAEGVGMIVLERLS
DARRHGHPVLAVIQGSALNQDGASNGLTAPNGPSQQRVIRAALAGGGLTPADIDAVEAHG
TGTTLGDPIEAQALIAVYGQDRQADRPLWLGSLKSNIGHSQAAAGVGGVIKMVMALRNGV
LPATLYAETPTPEVDWSAGTVRLLNEPVPWPANGRPRRAGVSSFGMSGTNAHVIIAQAPD
DAVTPNAAERPGVEGDGVASAAVPDGPPALSLVPAALAARTADGLRAQAGRLLAHLRDNP
GVGLADLGLSLATTRTAFEQRAVVLAADRDALERGLRDLAEDRVVSDVVRGVDRRGSGPV
LVFPGQGAQWVGMGRELLDTAPEFARRVAECEQALAPYVDWSLTAALRGGPDAPDLDRVD
VVQPVLWAVMVSLAELWRSNGVEPAAVVGHSQGEIAAAVVAGVLSLEDGARVAALRSRAI
TAIAGDGGMMSVPLPADDVRARLEPYGDRLAVAAVNGPGSVVVSGAADALDDLFASLTGE
GVQARKVAVDYGSHSAHVEPIRAQVLDALAELRPTPADIPFRSSVTGEWLDDDTVLDAVY
WYTNLRETVRFEDAVRGLLAAGHRAFIEVSPHPVVAFGLRETIEDAGADAAVLGTLRRDQ
GGLDRFVTSLAEAHAQGVAVDWTTVFAGTGARSVELPTYAFQRLRYWPELREANAVATDG
ADANDEVESRFWQTVEDEDLASLTAALDLGGDTPLSEVLPALSAWRRSSKEQSTVDSWRY
TVGWTPLTQDTAAAPPTGTWLLVVPPAGHPLADATRQTLTDHGVPVRVVHVDAGSPDADR
AGLAAQLITELADSGSGVDPADLGGVLSFLALDETPHPEHPSVPAGLAGTLALLQALVDL
GGTAPLWCATRGAVAVTAAETVLSSPQALVWGLGRVAALEHSDRWGGLIDLPETLDRRAG
DRLRALLARPDGEDQTAVRASGSYGRRLLRAPLADTPAPEGSWRPRGTVLVTGGTGAVGG
HISRWLAAQGADHLLLTSRRGADAPGAAELAAELAELGAGHVTLAACDVADRAAVTELLA
TIPEEHPLDAVFHIAGSLDDGVIDGLDPSRMHPVLRTKATAAVNLHELTAGYDLSAFVLF
SSTSGTISGPGLGNYAPGNAFLDALAQQRRAAGLPATAVAWGHWADGGMGDGAVGERLRR
YGVYDMRPELACQALQQALDHGETYLAVTDIGWERFAPAFTGSRPSALLRDLPDARRVLD
PARPTASGDTFGADDGADGELPALRRHLAGLADADRADAVLDVVRGYVATVLGYPGPQAV
EPTRAFSDLGFDSLSAVELRNGMNKITGLRLPATLVFDHPNCAELARLLLGELGGESADD
RAPRSGTAVTAGAATDDPVVITALSCRFPGGANTPEKYWELLADGIDAIAPFPADRGWDV
DNLYDPDPDHPGTCTAREGGFLKDMTEFDPAFFGVSPREALAMDPQQRLLLELAWEAFER
AGIDPLSLRGSRTGVFAGTNGNDYIPLLVASGEDVGGHLGTGNAASIVSGRVSYVLGLEG
PAVTVDTACSAALVALHLAVQALRSGECDLALAGGVTVMSTPGLFLDFSRQRGLASDGRC
KAFSDAADGAGFAEGAGLVLVERLSDARAAGRPVLAVVAGSAVNQDGASNGLTAPNGPSQ
QRVIRQALASAGLT
>A0A0N1G8N0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MSTHSEYGGGFGDNPDSPYSPHNADDFDGKIAIVGAGVRVPGAQDVDGLWQLLRGGYDAR
TALSDEQLRSAGVDPAAAGRPDFVRSAYLLDDIDRFDASFFGLGPREADILDPQQRFMLE
CAWQALEAAGRTASDPEVRVGVFAGSFFSTYLLQLYSNPQLVSALGDLVVRQSNDKDYLA
TRIAYLLDLHGPAVNVQTSCSTSLVATHLGCQSLLSGECDVALVGGVSIDVRQAAGYTYA
AGGILSPDGHCRAFDAGANGTAFGNGAVVLALKRLSDAVADGDRVHAVILGSAINNDGSD
KVSFTAPSVRGQSEVIAEALAVADVDADSIGYVECHGTGTPLGDPIEIAALTDVYRQYTK
ETGYCRIGSAKTNFGHTGAASGALGLLKAALAVEHAQLPPSLHYDAPNPAIDFAASPFVV
NDRLMPWKPGDRPRRAAVSSFGMGGTNAHLILEEAPPVRRQGRPRRWSVLLTGGHSARTA
ATAARRLADQLTDTDGTLTGGTATESTPTESTPADRTPADSTLANTAFTTQYGRRAPVHR
LAVVADSPESAAAALRAGEAAEVRTGRARPIAFLFPGQGSQYVGMARELYAEEPVFRAQL
DRCADEFARHLDTDLRELLFPAPESETTAQARLAETQYAQAALFAVEYALARQLTGWGVE
PSVMAGHSLGEWVAACLAGVFDLSDAVELVSLRGRLLQSLPPGAMLAVNLPEDEAAVLDG
VTVAAVNGPRACTVGGPVAAVDRLEALLRDKGVRVRRLDTGRAFHTPMVEPVLAEFAAAV
RAKGPRPPHAVFLSNVTGAPIGAAEATDPEYWARHIRQPVRFHDMLRTLGPEALVVEVGP
GRAHSALAAVARPDAPAPVPVLGPRGGDAEQRLSQALAALWTAGANVDWAAYQSERGLVR
VSLPPYPFERERHWIDAGDGAPLLPGAHPTATATPDEDSAEDGETAVLSVEAIRAEVTAA
WTLLIGEPPRSPDEDFFAAGGDSLLAVQLVSRLRTTFDCDLPLEEVFDRRTVVDLTELLT
AALLAPDTPDAADLTHLGDIEDDELAALLREIEGLSAEDLERELNSPAEDTGE
>A0A169PK31|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces laurentii|TrEMBL
MNQDGRSAGITAPNGAAQRDVFRRALTSAGVTADQVGYIETHGTGTRLGDPIEAEALADV
YGRDHGSPLYLGAVKTNLGHLEAAAGIAGLIKASLCLEHGEIPPNLHFTRLNSNISFVGT
TFGIPTATTAWPRTEGRRTAAVSSFGLSGTNAHLILEQAPPATPPAEDTRRPVSVLPLSA
RSESALAALAGRYAERLRTDDTALADVAHAAGTGRAHFRHRLAAVGATRADIAGQLASFA
RGEDVPGLVQGEADNGEVVFLFTGQGAQRPGMARGLYESQPTFRRAVDECAGILRPLLDR
PLLEVLFPDDPDDRRIQDTAYAQPATFVVEYAMAELWRSWGITPAAVLGHSFGECVAATV
AGAMSLADGLAFAVERARIIQEFCLPGTMAAIFASEEEVAAELAAHQGRIGIAAINGPAS
VAISGGRELVEAVCAAFSARGVKAKQLHIASAGHSPLMDPVMEPLRRAAQKITFHAPRIP
LVSNVTGELWPWDQAPDPEYWSRHVRGTVRFADGLATLRSMGHRTFVEVGPAPTLLGVIS
DTLPPGHEDLLLPSLRPGHDDWAVLLPTVAELYAAGAPVDWSGFDRDYTRARVPVPTYPF
DPVHCWLPARPWDGSAAPACDDTEEETGSAAARGRSSRGSRGARRSSRGRRRTGRIPTAA
ELLELDEPARLETLYERLALSVKDVLGSASTAVGVDDPLTSFGLDSLMAAELRNEIQSRL
GLTLQITVFLGGATIAGVARAIVEELAATGGGSPADPTLGGVGAPAAIQRVPRAADAARA
LLDELAGAPAQRDES
>S3ITW8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Microcystis aeruginosa SPC777|TrEMBL
MDFQDKKNLSENDQSIQTRVFKALSEAKEKLKAFESQQSEPLAIVGLGCRFGHNIATPES
FWSFLKAGKNNLREIPKERWNQQDFYDSDRNKVGKIYVSQGGFLDDVSQFDAHFFGIAPK
EAVAMDPQQRLLLEVAYEALENAGMATTTARRGKTGVFIGITNNDYARILTSNEDYNAIG
AYHISGNHTNAAAGRISYLLNLNGPSLAVDTACSSSLVAVHLACRSLRSQECRQALVGGV
NLVLTPEVVIALCRNQMLAPDGQCKTFDESADGFGIGEGCGVIVLKRLSDALQDGDHIWA
VIRGTAVNNDGASGGFTVPNGPVQRELIKEALADARLDAEAIDYVEAHGTGTSLGDPIEI
KAIAEALCVNRRKSNPLLVGSLKTNLGHLAAAAGISGLIKTALSLHYREIPAHLNLKKPN
PHINWDALPISIVTQNCPWNVNNGQLKAAGVSSFGASGTNAHVILSEPPQPQPQNPKISP
ILVTFSAKEPERLRLFTTQFVDELEQKTDLNVKDIALSLNTGRFPHKHRLALLVSNQENL
RQGIQAFLNSNGDEKQFQNIQNNSFDIIYGEAQSHPKIAFLCNYEEEISPEIIENLLNNE
PVFHEAFRQCEHLFKKYLEFSLQELLSSKKALEPQISLSVQPLLFAYQYALCELWKSWGI
SPSAILGSGLGEYLAAQQAGVFSLEDTVKLVAKRTRISPQNPNSEDLLSLLKSTPEVDSN
SPDITLIYQGEVVKKSLRNLVNRGEKIRQKSDEIAQGISTLHQMGYQIFLEMGIGANLIN
IGRQKLRVNSILWLSSLGKDCHSDQHEQRVLGQLYVRGFNINWEAFHRSHPGQKISLPNS
PFIRKRYWINSGNKSESSSYKNPNYYSGHPLLGDHFPSPLALLQYRGSISQHKPAFLGEH
QVFDQAILPASALIEMALAAGENQRVILENVEFKKALILKDTEDALQLIIEQKSFKIYHE
LEPNWEILVTGKIEELKSTNLTHCHLEEIAKNCPEEVDINSFYETYQKSGINYGSNFRLI
HQLKRGENTAFAQIKLTDILEREKYHFHPAMLDACFQGIAAILFKEESSVTYVPVRLGKL
AFFHPPDEQVVSAVRLKNSSPNPNIIIADIDIYSPQGQPLASLTNLELKAVQSQEIIPQE
IPPQIYLEEWIPCEELLGNGRDTLVAPQVIKNQIHPAQLEQQLGEKLAQYERLMEALEKL
SVVYIWEALTKLNGQPKLGQTYSEAQIANQGQIVDFYRPLLSRCLSILAEEKIVNQTKDG
WLFLKKLEAPSSQSQIKILRQEFADYPAEISLMERCGSALAEVMRRQVDPLELLFPQGDL
EAIASIYSEAAGAKLMNQLVATTISRAIENLPPYYPLRILEIGGGTGAATTGLLPHLPKE
HIEYVFTDISSSFLTRAKENFRNYPFIKYQTLDIEKNPFTQDFLPGSFDIIIAANVLHAT
ANLQKTLENVRSLIAPKGLLILLESTGARRWVDLTFGLTEGWWLCSQDLRRNGYPLISTK
DWQNLLIENQFEDINIIEPSQVKTRNLLNQSVIIGRSSEQLPSLPAKSYSHQIIWADSQG
IANGLIPLFQQRGISCSCVFTQDINPEIAEDYLSILRNSITSETRQILYFWGLEKIPGEI
DQQVEINCQRFLFFLQALLQQENPPTLILVTQGAVPAKAIKTLISPSQASLLGIAFSLVL
EHPELNFKAIDLDPDEVNAADKLLQEIYSNPQENRIALRGEQRFYPRLVQRKLEDGKINF
SPDAYYLITGGTGGLGLATTRWMIEKGARNLVLCSRRGAEGISPEILANFSSSGAKVTLK
KLDITDAEKLHAVLDECRSKYPIQGIFHIAGTLDDTTLLRLTPERFNYVLAPKVKGTWLL
HQLTLNDPLEFFVCYTSAVSLIGSAGQANAAAANAFEDAFIYYRQAHHLPGTVINWGPWS
EIGAAVDRNVLERLAAKGYGAMKPDLALNALEKILLNQIIRAGVIKIDWQQFPYIHQSFY
KNFLPQGKTQAAPSSEFLKQWQNLTLKERPNWLTNHIIMRVSTVLGRSNDETFSPQQGFF
DLGMDSLTSTELRNLLQTDFNCSLPSTITFRFPNVEALANYLQQEVLDNCQPVLTPQIKA
EISQKQPEKSSVEKSQLDDDPIVIVGMACRFPGGAKNLQSFWELLEQGKDAITEIPQDRW
DQETWYDPNPDVPGKIYAPYGAFLEQIEEFDGEFFGIIPRESVAMDPQQRLLLETTWQAL
ESAGQNPQKLRNSQTGVFIGCMTQDYAQLSYSPQAINAYTGSGTSVSMAAGRLSYVLGLQ
GPSMTIDTACSSSLVAIHLAYNALLNGECDLALAGGVNIILTPIISLIESRAHMLAPDGH
CKTFDESANGMVRGEGCGIVVLKRLSQAVKNGDQILAKIYGTAVNHDGPSSGLTVPNGQA
QEKLLHQALKRANLKPEQIDYIEAHGTGTALGDPIELESMSAVFGQRSPNRPLIIGSVKT
NLGHLEGAAGIAGLIKTVLALQHHKIPPHLHFKNPNPRFDWSSHIFEVPVQGKPWNISER
PRIAGVSSLGFSGTNAHIIVGEIDADLPQASENNFYLLPLSARSEQSLQELARSYQDILT
ESINLADVCFTTSTGRGIFPQRICILADSITTAQRALIDYQDGEDSDSLIRPILSETPPK
IAFLFSGQGSQYSGMGETLYNREVVFKETLDLCDQILEPLLEKSLLDLIFQEQNSQLLEE
TQITQPVIFSLEYALAKLWQSWGIQPSALLGHSIGEYVAACWAGVFSLEDALKLVTQRGK
LMGKLPHNGSMSAIYADYETVANALTSYENQVNIASANGSITVISGFKEIVEQLEKDFID
QGYKTKRLAVSHAFHSPLMQPILDDFSQVLKTISFHEPNLTIISNLTGKAVGSEITTPDY
WVAHLRNTVQFSGSSLLGMVR
>E0UL80|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Gloeothece verrucosa (strain PCC 7822)|TrEMBL
MMTSETTQPSPIKRALLALEDMQAKLEAVEAAKHEPIAIIGIGCRFPGNADSPERFWNLL
NDGIDAITEVPKNRWNIDEVYDPNPDVPGKVYTRLGGFLPQVDEFDRQFFGISARECVSL
DPQQRLLLEVSWEALENAYCRPEDLSKGLTGVFIGICNNDYAKVIIDERGRKQIDAYFGT
GNATSIAAGRLSYLLGLKGPSLSIDTACSSSLVAVHLACQSLRQKESDVALAGGVNLILS
PESSIVFSKTRMLDPEGRCKTFDASANGYARGEGCGVIVLKRLSDAQANGDRILALIRGS
AVNHNGRSSSLISPNGPAQQAVIHNALNNGKVSPSQVSYVEVQGTGTSFGEPIEIGALEA
VYCRNRSSDNPLAIGSVKTNIGHLEGAAGIASLIKVVLAMQSNTIPAHLNLKELNPYIDW
QNLPITIPRVSLAWPNQNTQKFAGVSAFGFSGTNAHLVLEEAPTLNFQSAQLDNFEITER
THHLLELSAKTPWSLEHLAKKYIDYITQNPDIALADLCFNANSGRSHFVHRLAIVASDLK
TLKEKLIAFVEQRQAEGVFTGQAASLPRIGAFFSGDISSALTLNYELYKSQPVFKEIISQ
CEDFLNKYLAFSLLDELDGKQDQNSLIHQSAYRPILLFVLQYALFEQWKAWGIEIAAVMG
QSVGEYAAACAAGVLSWQDGLKLIVESSGLALRQEMIEEFKLMIKDLKFSLPVMPLISGS
TGTVVTDQFTTLEDWFKHLSKKENTQFMTREIVGSKLEQQGCNVLFEIGIESFLSELNLH
KIPQLKHLISLNYSSNNWKIIFDYLAKLYVCGTQINWKEIDKSYFRQRISLPNYAWEKQR
YWVALEDDNTEDEISLSKNISHFEDLIKNLASSPELNADEVAFLPKLAELLKRESQKQTP
DEQAYSGENITLKAISRKAEDIQSWLAERIAKELGVNASEIDVRVPFDSYGLDSVLAIGI
ASAAKQYFNIEVTPMLLVHFPTIETLSKYVSEQLEASDLEVFEI
>E3JCX0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia inefficax (strain DSM 45817 / CECT 9037 / EuI1c)|TrEMBL
MAAQDEKLREYLRRALADARTAQRRLREVESAGREPIAIISAACRLPGGVDSPDDLWRLV
AEGRDAIGPFPTDRGWDLDGLYDPDPDTPGTAYTRHGGFLAGVADFDAAFFGISPREALA
TDPQQRLLLEKAWELFERGGLDPTSLRGTRTAVFTGVAGGDYAPGLYDTPQELEGYLGTG
NLRSVASGRIAYTFGLEGPAVTVDTACSSSLVAIHLAAQSLRSRESDLALAGGVTVMTTP
QGFVDFARQRGLAPDGRCKAFAAAADGTGWSEGVGLLLLERLSDARRLGHDVLAVVRGGA
VNQDGASNGLSAPNGPAQQRVIHAALASARLRPDQVDVVEGHGTGTTLGDPIEAQALLAT
YGQDRPEAAPLWLGSLKSNVGHTQAAAGVAGVIKMIGAIRHGLLPKTLHVDAPSPVVDWD
AGAVRLLTEARPWPETGAPRRAAVSSFGVSGTNAHLILEQAPPTAEGAAGTAGDGPPDQT
DGSDGSAQAGQPGPPEAPVVPGALPWVLSAKTAPALRASAARLAAAYDGQPGEPPRPLDV
AHALATTRARLGHRAVVVAADLGGFRDGLLALARQQEHPAVAVGAPTGGLAFLFAGQGSQ
RAGAGAELYRTFPVFAAAFDEAAAALDTALAGATAHPIARVAFAGALAEAGSPPAGVIDP
ALIDQTLYTQPVLFALETALFRLLAAWGVRPAHVAGHSIGELAAAHAACVLSLADAATLV
AARARLMQALPAGGAMVAVEAAEAEVRSALEAFDGSGPAAGGAADIAAVNGPRSVVVSGD
ERAVLALAARLADDGRRTRRLAVSHAFHSPHVDAVLAEFRAVATTLTYREPAIPVVSALT
GQPPRPGELTDPEYWVRHVRAAVRFADVVERLHAARTGTYLELGPDATLSGLAARTLGAR
ERAGATVPLLRKGRPEVASLLRALGQAHVRGAAVTWSALTEDLSPARVELPTYAFERRRF
WLEPARGPRGAGRPLSGPAGSGAGQPAAEAVDDLTEVRWEAARRPAGPARGRWAVVGADP
DAAGLALRIVGVDVVEFADLAATRAALAAGEQPPDYLLVPVAGAPPGETLDGGGPAAVRP
GGRSSPADIATLLAEETLAGATVVAVTQRAVAADPDLDLDLAATQAWEHLRAALLDEPKR
LVLVDVDGSEAAFQALPTALALARDDGEIQLAVRDSIVLLPRLARPRPDGPTRLGPAGPD
GLGPAGEGTWTRRLAEAAEDERAKLLRVLVVTDTAAVLGHDDAEAIDDDAEFADLGVDSL
AAVQLRNRLGAATGLELAPTVTFDHPTPAALAAFVGEELLRAADARSRQPDTAAGGSRQG
PLTALFRALGAADRYDEAGAVIGLASVLRERFDAAAVAENTPRPAQLGGGPKLPRIVCFP
ALSAISGPHEYARFGNLLRGGRDVLVPRSPGYAEDDLLPDSAETYVHLLTETVVPWVGSD
PFVLVGRSMGGTIAYAVAHRLEQLGLRPAGLALVDSYPLEAATLEGLREWWLAAMLRGML
DRIEQYQLVWSDSSLTTMGGYIRLFDGWRPPPLRSPVLLLRATEPIPGTIIDPTGARDWR
AFWPGASDVVDVPGDHFTILEDHCATTVAAIETWIEGLDWSGQNTDRENQQ
>A0A3E2YNF7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MW-13|TrEMBL
MVGSSVEELLAGLDAVAAGSPAGNVVSGAAAGPGAGPVFVFPGQGAQSARMAAGLVGRTP
VFDAKLAECQRALAPYLHVDLVSVLTGDDESWLDRVEVVQPVLWAVGIALAAVWRQAGVV
PQAVIGHSQGEIGAACVAGILSLDDAAKTVALRSRALAVLRGTGTMASVDLSAEAVTARL
AQFPGVGVAAVNGPATVVVSGPPQPVADLVRACTDEGLRARLIPVDYASHSASVQQVAEQ
LRADLADVSPRAGDVRLVSTLTGDWVDPASMGAQYWYDNLRQTVQFDAAVRVAIAAGHRA
FVEISPHPVLTMPVTAILDDTGATGHTLGSLRRGDDDATRLLTNLATAHAVGLPVDLTKV
LAATATVDLPTYAFDHHRYWPAPPLFLARADDEPDIDRWRYRVTWNALPDLPLDRLAGTW
LVPVPAGLDEEPLVQDVLSALGSVGVDAVPVEVDTTADAAALADLLRDALPDEGPASVLS
LLGLDERAHPDHPATTLGVTGTVLLVQALGSLDVEAPLWCATRRAVAVDAGDPAPSPAAA
AVWGLGRAVALEHPGRWAGLVDLPDLLDPWTGVRLCAALGDNGGEDQLAVRDSGVFARRL
TRITEPEPTASGEPTDDGWRLRGTVLITGGTGGLGGHLARWAARSGAAHVLLASRRGPDA
PGAAELEAELTDLGVRVTVARCDVADRAQLADLVATVDGDAPLSAVLHTAAVLDDGIVDT
ATAQRLHTVAAPKCLAAAHLDELTRDLDLDAFVLFSSVAGTTGNAGQGAYGAANAYLDAL
AERRRAEGRPALSVAWGAWSGAGLPADNERAQQRLRRGGMVGMDPDLAVEALARALRRDE
TTTLIADIDWGRFAPAFTLVRPSPLIGDLAEVREAAREATPEATEEEPAAPSGALARRLA
GLTPAERAEALLELVRQCAATALGYGAADDIPATRPFRDLGLDSLTAVDMRNFLATATDL
RLPATLAFDYPNPTVLATHLDELLTGAVPDVATPAPAAPGVDDDPIAIVAMSCRLPGGAD
DPERLWQLLAAGGDAIGEFPTDRGWDLDRLFDSDPENEGTSYASEGGFVTGVADFDAGFF
GISPREALAMDPQQRLLLEASWEVIERAGIDPQALRGSPTGVFVGTNYQDYRNLMYSAEG
AEGHLMTGNAGSVLSGRVSYTLGLEGPAVSVDTACSSSLVALHWACQALRQAECSLALVG
GVTVMSTPGVFVGFSRQRGLAPDSRVKAFASAADGTSWGEGLGVLLVERLSDAQRNGHPV
LAVIRGSAVNQDGASNGLTAPNGPSQQRVIRQALANAGLTPADVDAVEAHGTGTRLGDPI
EAQALLATYGRERPADQPLWLGSIKSNIGHTQAAAGVAGIIKMVLALRYGYLPQTLHVDE
PTDQVDWSVGAVELLDEGRIWPVTGRPRRAAVSSFGISGTNAHTILEQAPELPVPTEPAG
DPDRLPVVPVLLSARTASALAAQAGPWADRLTGPEAPPLVDAGWSSVVSRAALEHRAVVL
ATDRIALRTGLRALGAGEESPLVVIGAVAPRPKVAYLFSGQGAQRPGMGRELAAAFPAFA
AALDEACAVLDPHLPGPLRPVLNASPGTADAELLDRTEYTQPALFAVEVALFRLLQAWGV
RPDVVAGHSIGEFAAAHAAGLLTLAEAAELVAARGRLMQALPDGGAMLAVAAAEADVLAS
LGDRADRVSVAAVNGPAAVVLSGAGDAVEELAAEWSARGVRIRRLTVSHAFHSPLMEPVL
DDLAAVAARLEPRTPTVPMVSTVTGAVVDPAELATPAYWVRHARDAVRFADAVTALRAQG
CTGYVEIGPDGVLTALTQAVLAEDAPAGGRAPLVVPTLRRDRPEPAALLRAVAALHTHGV
SPDWSVLYEGTGAQPMDLPTYVFDRQRYWPQPPDWAALAAVEDDSTEVERRFWAAVEAED
FESLTRELDVDRDQPFGAVLPALSAWRRRGRERSLVDGARYRVVWEPLAGPPTEQDSGPW
LVLLPADRADDPDLNSCTWTLGGDVTTVPVDTAADPDELGGQLADVLGEALDGATGTLSI
LSFLGLDDAPHVEHPALPRGLAATVQLLQELTDTDAAARLWCVTQGAVGVGDGDVPVNPR
QAMLWGLGRVAALEQPARWAGLIDLPATLESWTAMRLGGILTGGAAEDQLAVRDSGVLVR
RLAPAVTAGEPAPWQPRGTVLITGGTGALGGHLARWVAGAGAERVVLTSRRGADTPGTAE
LLAELEALGVSGRVARCDVADRVAMTDLVAELRREGPPLRAVVHAAGVSEVVPLADTTLE
DLAYVVAPKLVGTELLDELLDGVELDAFVLFSSIAAVWGSGGQGAYAAGNAYLDALAEQR
RGRGLPATSVAWGPWTESGMFDDGAPEQLRRRGLRVMPPGVAMAGLRHALAAGDVCVTVV
DVDWATFQPLFTALRPSPLLADLPAVRALTETVADGPAPAAPATRDLLAGLRALPGEERR
AALLEMVRVDAAKVLGHSSGDVIETDRGFLDLGFDSLTAVELRNLLTAATGHELPTTVVF
DYPTPAGLADHLHEELFPDAGAAAGDGDGDEASVRRALAAIPLDQLRQAGLLDQLLQLAH
AAGPVAGTPVAVPAAPEAEIRELDVAGLVRMALEGSDS
>B0TPB0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Shewanella halifaxensis (strain HAW-EB4)|TrEMBL
MSQTSKPTKSAKATEQAQDSQADSRLNKRLKDMPIAIVGMASIFANSRYLNKFWDLISEK
IDAITELPSTHWQPEEYYDADKTVADKSYCKRGGFLPDVDFNPMEFGLPPNILELTDSSQ
LLSLIVAKEVLADANLPEGYDRDKIGITLGVGGGQKISHSLTARLQYPVLKKVFANSGIS
DQDSEMLIKKFQDQYVHWEENSFPGSLGNVIAGRIANRFDFGGMNCVVDAACAGSLAAMR
MALTELTEGRSEMMITGGVCTDNSPSMYMSFSKTPAFTTNETIQPFDIDSKGMMIGEGIG
MVALKRLEDAERDGDRIYSVIKGVGSSSDGKFKSIYAPRPEGQAKALNRAYDDAGFAPHT
LGLIEAHGTGTAAGDAAEFAGLCSVFRDENDTKQHIALGSVKSQIGHTKSTAGTAGLIKA
ALALHHKVLPATINVSQPSPKLDIENSPFYLNTETRPWLPRVDGTPRRAGISSFGFGGTN
FHFVLEEYNSEHRREDSEKTKYRQRQVAQSFLVSAADKSALISELTKLASASTQAEFILK
DAAANYAVRQLNSTAPRIGLVAATSDELANLIKQAIAKLSSSDDASWQLPGGTSYRAAAI
EGKVAALFAGQGSQYLNMGRELACYYPEMRQQFVTADKVFATNNKTPLSQTLYPKPVFNK
DDLKAQEAILTNTANAQSAIGAISMGQYELFTAAGFNADMVAGHSFGELSALCAAGVISA
DDYYQLAFARGDAMATKAESKDGLEADSGAMYAIIHQEKGTTDLATLEATIAKFNGVKVA
NYNAPTQSVIAGPTDSTGDAAKALAELGYKAINLPVSGAFHTELVGHAQAPFAKAIDAAK
FTKASRALYSNATGALYDTSAAKIKASFKKHMLQSVRFTSELEAMYDAGARVFVEFGPKN
ILQKLVQGTLANKASEVCTISINPNPKGDSDLQLKQAAMQLAVSGVVLSEIDPYQADIAA
PEKKSPMSISLNAANHISKATRAKMAKSLETGIITSQIERVIEEKVIEVEKVVEVEKIVE
VEKIIEVAVQQPSNEQAAHNQVNTNPVQAHSVIASSVKENQVVPKNSQPAAHSISSDALS
NFFAAQQQTAQLHQQFLEIPQQYGETFTTLMTEQTKLAGSGVAIPESLQRSMEQFHQLQA
QTLQSHTQFLEMQAGSNIAALNLLNGTPTTTYAPLIQSEVVQSQVVTQPAAITVTAAAPA
PVQTTALQTAAIATTPQVQAPQVSRQTAPVQTVVVPAKVEPVVATNTSTAEGSSAAAALN
ISAQKVQATMLEVVAEKTGYPTEMLELEMDMEADLGIDSIKRVEILGTVQDELPGLPELS
PEDLAECRTLGEIVAYMNSKLSSAPVTASTTATVAAVATANGLSADKVKATMLEVVAEKT
GYPTEMLELEMDMEADLGIDSIKRVEILGTVQDELPGLPELSPEDLAECRTLGEIVSYMN
SKLPSVDSQVAVISAAPAVVNNNAATVGLSADKVQATMMSVVSDKTGYPTEMLELEMDME
ADLGIDSIKRVEILGAVQDELPGLPELNPEDLAECRTLGEIVSYMNSKLPSVSAQVADTS
AAEASSAAVNVSVSSLSASQVQNTMMSVVAEKTGYPTEMLELSMDMEADLGIDSIKRVEI
LGTVQDELPGLPELNPEDLAECRTLGEIVAYMGSKLSTSAAAAQVAQVSAAPAANGLSAE
TALSSQTALSGETALSAQKVQATMMSVVAEKTGYPTEMLELSMDMEADLGIDSIKRVEIL
GTVQDELPGLPELNPEDLAECRTLGEIVAYMNSKLPTVSAQVADTSAAVNISTAKGSLSA
TQVQNTMMSVVADKTGYPTEMLELSMDMEADLGIDSIKRVEILGTVQDELPGLPELNPED
LAECRTLGEIVSYMNSRLSTTVAAVSGAVKSVAETITSSLELPPHSEVALKKLNAANKLE
DCFAADTTVVINDDGHNAGVLAEKLTKQGLNVAVVRLPEGQPQSPLSSDVASFELASGKD
SELETSIAAVIAQIETQVGTIGGFIHLQPEVNATEQANAVNLNAQSFTHVSHAFLWAKLL
QPKLTASSDKRRCFVTVSRIDGGFGYLNTDALKGAELNQAALAGLTKTLSHEWPEVFCRA
LDIAADVDATHFADAITAELFDSSTQLPEVGIAVDAKGNVSRTTLIAGDASEKHTACELN
SSDKILVTGGAKGVTFECALALAKRTQSHFILAGRSELLAIPTWAENKQISELKPAAIAH
IISTGNKPTPKQVEALVWTVKSSIEINTALEAFAQVGASAEYVSMDVTDSAAITAALNGR
SNEITGLIHGAGVLADKHIQDKTIEELARVYGTKVNGLKALLAALDSSKVKLLAMFSSAA
GFYGNTGQSDYAMSNDILNKAALQFTARNPQAKVMSFNWGPWDGGMVTDALKKMFTERGV
YVIPLKAGAELFASQLLSETGVQLLIGTSMQGGADTNKADGSNKADGSSQAEGSKEAASV
KKLNAGEVPSALIPQSLAPMTLTRALNPNAMVFIQDHRISGNPVLPTVCAIQWMREAASK
MLGSQVKVLDYKLLKGIIFESDDIQEMTLELTAVVANSELKACEAPKLQALITNQGRPQY
KATLVSAEGSLDAASKSFAALGDAVTSADELYSNGTLFHGPRLQGIKQVFNFDDKGLLAS
CQLPQVSDSDCGQFVATTHIGGSQPFAEDLLLQAMLVWARLKYGAASLPSSIGEFISHKP
LAFGDKGMLELEVVKTSARSLEANVALYHENGELSAMMKGAKVTISKNLNSAFLNEAALS
KGERA
>A0A086JHY8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii GAB2-2007-GAL-DOM2|TrEMBL
MANAEKLVKLHGLWFRSLWKWAEKIPHEDAVIWLDENGSKAASLTYQKLRREALIIATCL
RQVHCQPGDRAILCYPPSVSFVPAFLGCQICGLTAVPVYPPGSNDRDSDSIQRIVAMVKT
TRPSVVLSSSPLRYFLKEVFPGAAARCVSDIRWIFTDELPDHVEAGSAFELDSLDIKSET
PAFIQFSSGSTGNPKGCVVTHMALLHNIHLNWRMCGAFHPGTEESLYDLPVESYAEFTEK
YQKHLVATWGHRLRSFSWLPVTHDMGLVGMLCVPLFFGCTAFFMSPIDFVRAPHSWLGGM
SKFGCSFTAAPDFAYALAARKVPDDLVLELNFEKILACVNGAEPIRPATIEAFLQKFAPA
GFQPWMMSPAYGLAEHTVGVTGRGSEGRKPMSPKIIEVNNEKVAQGDTVELFKRSGKQEN
EMRTKLIVGCGIPHEDVIVKIVDPRLLQELSEWQVGEVWVSSPSAASGYFGSPVETASTF
NLHLNTADGATRGDRSFLRTGDLGFLGDGELFITGRLKDVVILRGCNYYPQDIEEAVERC
DSVRKGGVMAFSISTTDDAEGLGVAAEIQKGSEKPAKLKLIYADIVRTVNKVLHLPLQRL
WLLRAGSLPKTTSGKPRRSEARRRLLQAERCDDILYSYTRNLSHSGHLPFRPGTFELDME
QKQEDSASTSKSEVNKSLVESLSTAKGARHTDDGFIFTNGQQNLHEAKKDQHGTSDSTLA
EPVSNAILDPITRVTDALLVTADGTSVHKDEEELSLVAECFACVTGVEKSCLRPDTPFLS
LGLDSLTAVELANEIQRRMKQPVEPFELFEFADLRSLALYLRNKKLDHGKDARGRQTKSS
PERSLGIVQVQRPSVFVTGVACALPGSCQTPDKLWEILDAGIDCVGPIPPNRNFCASQNF
AVIGEPRTANASFCVTEGGFLDDVDLFDNSSFGIPDAEAMTMDPQQRLLLMKAVEALHAA
GMATIDSRSAPIATFVGCCSTDWQRMNLGEQIQSFSATSHSASMLSNRLSYTLGLTGASI
TVDTACSSSLTALHCAMQELQHRHVPCHTAVVATVNLLLTTDVTLAFARAGFLSPTYRCK
TFDDAADGFVRSEGVVVFVLQTDVSETPTPSFKNQQEDNEGGQGECGTRIPASGYLCRIL
ASTVVHGGKTGSVTAPSGSSQELLYKQTFACAQVPPRAVDLVETHGTGTRLGDPIEISAL
CNSFAPDMETRKHRLVLGALKTNLGHLEGASGLAGLLKSVLCLNRQRVPPNLHLRKLNRF
IDFRSLPVLLPTKTVPLPASSSETKEAVALVTSLGFGGTYAQVAVQVPSTTGNEMLLRNQ
EPVQWNKKCFDVGKLVSQSNSFQSAVSHNDTKGPCFWEVGWEFLLEFDSITLTLPTLPEQ
APPAKWLVLTSPKAQQSFRKFSVNIFLPGIRMTFACLEELKAPEHLEAILKAETWTAIVS
TYTTETGSCMTDSSDLIGRTLQILQTYGQMASQSAVLPRILFLTQGCFQVGAAASLLRAS
PYNAGIIGFVRACRLEIESLSGRKAPIYLIDFAANGTLTETLSAVSKLLGMIDIRNVDET
EFAICGKRVFAPRLLPLHLGLEEILPAYDHYMDLTKKADESPAGTAKFPRLVEPANKACR
VRLLALCLDEIFPIEAISPASKAFELGESRPCTLPYGYRNRRQKAFLYQMERAFV
>I7GG43|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)|TrEMBL
MATRQPAAGPARDLPPRTGHESAEQRLDHHRVACPGHRVRNSCSSGYPSRPTAATNYSQA
VSRDEGVPMPNTDHTSRQPLAIVGIGCRFPGGADSAQRYWDLLCNNIDATREVPENRWNA
AKYHDPNPAKIGKIVTRRGGFLDQIDQFDPQFFGISPREAHSLDPQQRLLLQATWEALED
GGIPADELAGTDVGVFVGGFTLDYQLLQNQGRTSRYRFKPHSATGMMMTMLANRISHAFD
FRGPSMAIDTACSSSLVAVHLAAQSIWDGDCDVALAGGVNIMVGPNTAIAESKSGFLSPE
GRSKAFSDTADGYARGEGGAVVVIKPLAHALRDGDDIYAQILGTAVSQDGHTDGITVPNE
EAQEAAIRMALQRAGVEPNDVAYVEAHGTGTPVGDPIEMRALAGALTTDRDATRPLVIGS
VKTNIGHLEAGAGVAGLIKAALIVKHGHIPANLHLKNPTRHVSLTELKLDIPTIGRPFPE
CDRRIAGINSFGFGGTNAHVVLAEPPAARHSAETGDHRVLTVLPISARSEEALVATAGRL
AGHLAAHPEVTLADLGYTLSHRRAHLNHRHTFVVDSIDEARRQLQAVADGGQISAGRAGE
ARLAFVCTGMGPQWWQMCRGLLDVFPVFTDSIHRTDRELSRYADWSLLEELTRDEASSRM
GETEFAQPANFAIQVALAEQLAHFGITPDAVIGHSAGEVAAHHIAGLLTFEQAVHVIYHR
SRLQQRTTGQGRMLAVGLDAETLMQILDEKILDQFGRRVSVAAINSPSAVTVAGDADVLE
DIARHLDEAQIFNRYLAVKVPYHTHYMETIKDDLHTAFASLSSKAATLPLYSTVTGELLD
RYDAGAAYWWQNTRATVLFEPAMRRMLDDGYTHFVELGPHPVLAASILESAGTQRVSVDA
SQRRGQDDARTLLNCVGALHSRGHEVAWDMVQPRAGAHPVKLPSYPWQTKRFWNDTHEAE
EALFYRPVHPLLGQPVRAVHPTWEAEFSTLTVPFLADHQVQGSVVVPGAVYVEMALAAGR
ETYGSDLSVDNLVLHRAVILDDTCDPVIRTTVDQDDGSVEFAALIATADTDLKWVITATA
ELNTLPRAPRAGDTGGGAVTSTDGDTFYQRTQALGFDYGEAFRSVASVTAGRDWAVAQID
IPQSISADVDTYRFHPALIDGAFQTLFGAPFSGQEENTDPYLPTRIRHCAVYGPPAEHMT
VRARVLSATHDAVECDITITDPSGGVLAAFDGFTVQSLSASSRMSADHIDKGLFALEWSP
VTDTPDTAHGDESTWLILTDNGGVGEAIADGLRLRGHHVHTVAHDPTGEIDWPDMLATHL
SGERTGLIDCWPLEVTDAATDPAGTATVLRIVKALATLDGVTPRLYLVTANAQPAAGTEL
TGTELTGVEQAAFWGLGRVIGHQELGEYWGGLIDIDHADAPSSTAEQICGHVLGDGAEDQ
IALRGNQILAPRLRPCSGLTKPFPTKLTADATYVVTGGAGALGRVVATYLAERGARHITL
LGRSPISPRDRWASITEDDAHHATVDAIRAIERLGAHVSTASVDITDSDQVRAWLREHTG
SGGRPVRGIVHAAGSVRDQLLVNMGEDDFAEVLAPKITGTRVLHNVFEDHDLEFFVMFGS
AGSTIAAPGQGNYAAANAFLDAFAHHRQGLGLPALTIGWGPWSVGMVEELGLEKVYAQRG
IELITPAVGARIIDRLLSQSVPAVVAMNADWSRARQVGFGGLVPKMFGELGTADTVGGQD
GVGPSILELLAHTADADRPAVIAEQVRRLVAAVFDCAVTDIEPDDMLDDIGLDSMMAMDF
RVRINSAFSIDLPVLEILRGVSVNSLSARILAELRDIHGVAPVEPDTGETASEPTTTDDD
VERLLQDLSEAEMRQLLAELEASGTEAGGAIS
>A0A655HZJ5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MTGGLDAADLARLGREGVLALSTAEALELFDTAMIVDEPFLAPARIDLTALRAHAVAVPP
MFSDLASAPTRRQVDDSVAAAKSKSALAHRLHGLPEAEQHAVLLGLVRLHIATVLGNITP
EAIDPDKAFQDLGFDSLTAVEMRNRLKSATGLSLSPTLIFDYPTPNRLASYIRTELAGLP
QEIKHTPAVRTTSEDPIAIVGMACRYPGGVNSPDDMWDMLIQGRDVLSEFPADRGWDLAG
LYNPDPDAAGACYTRTGGFVDGVGDFDPAFFGVGPSEALAMDPQQRMLLELSWEALERAG
IDPTGLRGSATGVFAGLIVGGYGMLAEEIEGCRLTGMTSSVASGRVAYVLGLEGPAXSAT
STPPSSGWGRARPSRWTPSNGCCWSCPGRRWSGPVSIRPDCAAAPPGYSPG
>A0A2Z5KFC6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. Go-475|TrEMBL
MAVGRDDRSVAVVGIGCRLPGGITGLDGLWAALRDERDLVGEMPPDRFPKDRFVDPGAVR
PGRSYTAAGGFLDDIASFDAAYFGISPKEAAHLDPQQRLLLEMAAEALDDAALPAEALAG
SDTCVYVGVSDPAYGTVLSMLEDHTSPHTMPGATLSIAANRLSYAFDLRGPSMAVDTACS
SSLVALDRACRTLREGSSRVALAGGVNVLMNPFSFAGFSYAGMLSRRGRCAAFSAEADGF
VRAEGGAVLVLKRLADAVADGDRIHAVLAGTGSNCDGRTTGMTLPSSQGQEALLRAVCEE
AGIGPDDLVYFEAHGTGTPVGDPAEAQAVGRALGTRRGAGPLPIGSVKSNLGHLEPAAGM
AGLLKAILVLRHRTAPASLHALPLNPAIDFDALGLAPTVTPVELPRTARAAVGVNSFGFG
GANAHAIVVPPPPGPPAPQPVDRPLPVVVSARSPKALRELTARMAERLRGAAPEEFYDLA
RTSTLRRSAHPHRAAVLAADPGQAADALENLFTDAPAGGAVTRRAERGAVAFVYSGNASQ
WPGMAAGLMAAEAAFRAAVEETDAALAPHLGWSVAKELERPTAARWARTEIAQPVLFAVQ
TGLTALLAAQGLRPAAVAGHSVGEVAAAHAAGALTLEQAALVLAQRSRTQATTAGRGRMA
AVGLAEDAARAELARFDGALEIAGINSDRDVTVAGDPDALAALGAGLTARDVFFRELDLD
YAFHSRAMDPIEEPLRAALAGLTPGTARVPFVSTVTATPLTGPELDAAYWWRNVREPVRF
AEAMDRLADEGVGIVVEIGPHPVLRPYLRRTDLTYVPTLHRDGDGPREATAAVAALLAAG
ADVDWPTHFPHPGRVADLPAYPWQRDRHWHGTPQDLVLHTSGTGALDHPLLGERQPAPHP
LWHGGVEPQLVPWLGDHRVGGDVLMPAAAYVEMAVTAGLRALDRPVEVRHLEISRPFAIA
WPDPAGAALQTAVTPADGTLTISSRDTRDTEVQPVVRAQVRTRLGTAPAPLDIAAVRARC
PRALTGPDFYEHCHRVGLELGPGFRLLHSLDVGDGELLARYRLDHPADGYTVHPVLLDGP
LQATVALADRPTPEAAGYLPSAFGAVRVWRTPAQEGVVHLRRCSRSANEICWDITYADLD
GTVSAQIDKCRTRRARLSDHAPLTVQRTVLRAAPHPSTPAPPSPLPAPAALAKAARGRVA
AARAAWEDSGHAAFTAAAERAGAACWAAALRELTPRPGAPFTMPDLVGRGLAPRHRRLVR
LMLPLLAEHHLAEADGDTWRLTDGTPSPEESLRNLVAGHPRFGPAALLINSQLRQLPEVL
RGDVDPRDLLPVGDTFLEQWQETAPAHRFTHRVVQALLDRIVHDWPADRPLRVLEVGATT
TALTAAVLPLLPADRAHYTCTAPSNAPFARARHRFAACPFIEYRTLDPDADPAVQGFAPA
SFDLVLAGDALHATADLAATLGHVRALLAPGGHLLATERHHDRLDALLLGGLESWWKRGD
RALRPTTRLLPHDAWIPLLERCGFTGPWQTGPADHSVVAAAAPAAATAPPTLPAPPPDTA
WIVATETDTETPTARELAALLGPATVLTAPADTGAWTAALPAEAAPRIVLLLAEPDPRQL
VARTTHRASVLRALAAACRTRPEDRPPQVWLVTRPTGLFPAPERPAHPEDAAVWGAARAL
ANEQPGLGLRRVSLDRTTDPAADARRLAAELLTPGHSPDGTDGADEDEIVLTPSGRFTPR
YIEHPADEPPAVRTGAPFVLETRDPGPARRLIWRETAVPRPGPGEVAVELRAVALNYRDP
LRANGLLPPEAVEDSPLSRGLGTDGAGIVCAVGPGVTGFAVGDRVCGAVPAALASHSVTS
ANALLQIPDGMSDAEAATFPVAFLTIHHALVEQARLAAGETVLVHGGAGAVGLAALQCAH
ARGAHVIATAGTETKRNLLRSLGVPHVLDSRSLDFVPRVRELTEGRGVDVVVNSLSGEAI
AHGLDLLRPNGRFVELGKRDIYLNNTLPLRPFDRSLTFIGFNLDHVLLDPERGARLVADL
VSHIDRGVYRPLPHTVYPAARVEEAFQVLQHSRHIGKVVVSFEHPLDEPVPVRPAPRVPT
LDADGTYLVTGGASGFGAATARWLADHGARHLALVSRRGQATPEAPALLEELVRRGVHAT
AHAADVTDEAALRRVVDAVDATGHRLRGVVHAAMHLDDAALADLTDDRFTAVLAPKADGA
ALLHRVTADHDLDLFLTYSSIAAAVGNAGQAPYAAGNAYLEAQARARRAQGRPATTLAFG
PIGETGYVARHGIGDALAERGFQPLPVAEALATAGGLLQPGTDVAGIGRYRWSRARRLLP
ALATARFTGVVPADAAPDPEGRADLLRKLSAMTSDDARAAIARTLTRLLAAVLHSDPDEL
DPARPVTDFGLDSLLSTEFLVRAGEHFDVRLTAAELMSSDRTLTHLAHLVHTRLDLA
>Q39J94|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)|TrEMBL
MNSKIAIIGIACRFPGGANNPGDFWQLLRDERDAVTEIPADRFGTDFYQHPSKREPGKSY
TFSAGVVDNVAGFDAAFFGISPREAAQMDPQQRLLLELAWEAFEDAGVRPADMRGSNCGV
FVGAASMDYGNRNMDDLNVIDPYSATGNTLSIASNRVSYLFDLRGPSMSVDTACSSSLVA
LHQAVKALQSGEADVALAGGVNLLLHPFGFVSFSKASMLSPRGRCRAFDATGDGYVRSEG
GAFVLLKPLDRALADGDTIHAVIAGSGVNSVGHSPGGISVPGAAAQASLLRSVYARAGID
PQSLAYLEAHGTGTAVGDPIEARALIDVVSGERPADRPLLIGSVKTNIGHLETASGMAGL
LKAVLCLKHRAVPRSLHFVTPNPGIDFDGGRLRVVDRYMPLDAGDAPLTVGVNSFGFGGT
NAHVVLTEAPAANEASTVVPEHEPTQAQLSPLVLTARSANALGALAGRYLAMLDSGGDWQ
ALAAAAARRRQWLEHRAIVAPAGVAEGRAALAALAQPAAEGLPACVATGQAPTDAVRTAL
VFSGNGCQWVGMGNELYAENAVFRAALDEVDALWCADGSPSLVDVMRGGPSAEWLAGAGA
EWLAATENAQPLLFAIQVGMIRVIDARGMRYDAAIGHSVGEIAAAWVTGALSLADAVRVI
KIRSRAQAMTRGSGRMAAVGIGDAAARELIARHGLARRVEIAGINSPDAVTLAGELQGLQ
ALEAALRGSGKFFQMLDLDYAFHSSHMDRIETVVLAELASLRPQPGDGTFVSTVTGGALA
GTELDARYWWRNIREPVRFGDGIAHLIEQGVRLFVEVSPHSILRTYVKQAFAAAGATGAA
LPTLKRDHGSAAMLQQAILAAIAHGANVDPGRFAPGESRAALPSYPWQRDRFWLTPTIEG
YGLVNRRREHPLLGYRLHEHAFAWENQLDPAKLPMLADHVVDGGVAFPGAGYVEMALAAA
RTFFDTPDAALENVEIRTPVVFQPQQAKLFRLVIEPRTATFTIETRDRMSDGAWTLNVTG
RMLESGNTLGDASIVPSGVLDRLLALPAADGATLYANTAAIGLSYGPAFRWVRTVRVAVD
DGAALADIAAPAICGDARALSAYLLHPALMDSGFHPLFALLAAHAREGEHPAYVPVQIGR
VDYLRGDTVERVLVRIDRHSPHSIVAHFEFLDARGAIVARLGACRFRRVDLVGRRQNLPA
RFVYRLEEVPLPGDVNAAGLPAPDALLAHAAARLDAAGHDGRRTQHLTEILPLLDVLASL
YALRAFDALGAFAGTWQPAAGRAALATRLADMLVEDGLAHRDGGLLVRDDAACAALPPLD
ELWRGLLAESPGHVAELTLLAHCGAALPEVLNGTKDGARLLSPTGHSLVEQLLAASPTWQ
HVHALLAVSVEQAVDAWQPARRLRVLELGATDGDVLQTLGMHLAAARCDHAIAATAGQLA
GFDADAEAAVRTVALQSGERLSLAADEAGPYDLIVANRALSGRHDVADALNAMRSWLAPG
GLLLLAESRRGRFSDIVSGAQASSTEADAPVPLTPADLDAALEGAGFVDVVRHVEQSLDL
DGTPTFVIARNPASAVVAQRGEDPSDLDTLARSEQWLVMHAPDAAGSFGGRLADALARAG
YPADIVDVTHAADAIASLPAGRPAHVVFCAPETPLAESATGDGLMDAQRNGVIALAALVR
ALGAQPNAATRLTVVTRGGAPFAGTANAHPEQATLWGLGRVLANEHPELACRLIDVDRAA
DRIPDALIHELTGAAVEEEVVLGAHGRQVPRMLTATQAAARDDGAIACAAVLAFDAPGSL
RNLEWFALPESPLGDDEVEIEPVATGLNFRDVMYAMGLLSDEAVETGFAGATIGMELSGR
VVRVGNAVTEFAPGDAMLGFAPASFATRVRTRAQAIALKPERLSFEEAATVPTTFFTAYY
ALVELARLRRGERVLVHGGAGGVGIAAIQLARHFGAEVFATAGSDEKREFVRLLGADHVL
DSRSLAFADEIRALTGGQGIDIVLNSLAGEAMVRSIDTLRPFGRFLELGKRDFYENSHIG
LRPFRNNISYFGIDADQLMGALPELTARLFGEVMALFEAGVLHPLPYRAFPAERAEDAFR
YMQQARQIGKVLVTYPSGTPAPTRGVARAGSLALDPHGTYLVVGGTGGLGFASARWMVER
GARRLTLASRSGDLAAAAREEVEHWHKTLGVTVDVVSCDVTDAAAVDAMIDAIVRRDSPL
KGVLHSAMSIDDGLVRNLDDARMAAVLAPKVAGAWNLHRATRALPLDLFVVYSSATTYLG
NPGQSNYVAANSFLEALVEHRRAAGLPGTFMAWGPLEDVGFLARHADTREALQSRIGGAS
ITSDEAMVALERALVAGAAGEAVVRLDWHAVARGMPAAKARRYSLLQSHAKGGDARDGGT
QLREEVLALPRDEAIALVARTLQGQIARILHMTPDRIALDKSVLDMGMDSLMGMELGLAV
EEAFEVKLSVMAIAEGASVTTLAGRIVDSIGASTDADAGSATDAAQEAVAALAAKHAIDG
EARAMLDTRQAPVAGQASPTLEVAR
>Q0RTS3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia alni (strain ACN14a)|TrEMBL
MSSGSAVSANADDTPRGAGDPIAVVGLACRLPSAPDPAAFWRLLRAGGDAVDRGPTVPRR
LGAAFGAHLDDVYGFEPEFFGIAPREAAQLDPQQRLVLELAWEAVEEAGLRPETLAGSLT
GVFVGAITSDYATRVLRAGPGAVTRHTLTGQSRGIIANRVSYTLDLHGPSLTVDAAQASS
LVAVHLAADSLRRGECDLALAGGVQLNLVPDSTETAARFGALSPDGRCYTFDARASGYVR
GEGGGIVLLKRLSSALADGDTIHAVIRGGAVNSDGATDGLTLPSADAQERVLRQAARAAG
VDTRDIQYVELHGTGTPVGDPIEAAALGRAFGAGRAADAPLHVGSAKTNVGHLEGASGIV
GLLKTVLAISRRELPPSLHFATPNPDIAFDELRLRVQTDHGTWPAGDRPLIAGVSSFGMG
GTNCHLILAEPPPAETAPARLASTETPPTETPPTTAPGRPAADDEAAAQALPWPVSGRDE
AALRAQAGRLHDRLTDHEPPAFDPVDVGHSLATTRTAFERRAVVIATSPAQFLTALRRLR
DGEQDAALVTGPPDGAADRGGVVLVLPGQGSQWAGMARELLATSPVFAERIAACAEALAP
HVDWSLPDVLAGAAGAPPLDRVDVVQPALFAVMTALAAVWRSYGVRPDAVIGHSQGEITA
AHLAGALTLADAAAVVARRSRVLAELAGTGAMASIPLPAAAVLERLGGPDAVLAVAAVNG
PSSTVVSGDPAALDALIAGYAADGVDVRRIPVDYASHSPQVAAVEAPLLDLLAGITPRSG
DVAFYSTVTGEAVDTSRLDAGYWYANLRGTVRFDAAVRAALAAGHRTFIEVSPHPVLTGG
IRAIVEDAARSAAGGGAGPAAVVGTLRRDDGGLDRFLRSLAEVHVAGGTVNLAAAYPARA
RRVALPTYPFQRRTFEVDAPDGPALNGTTPNGTTPNGSTPNGSPPNGTVAPIGVGPSGAE
TAAAAADSAASDAVPSSALARRMAGLPAPEADRVLLDVIGASLTIVLGHAAGSVQAERTF
ADLGFDSVSAVEFRDRLAAATGVALPTTLTFDYPTPRRLAGYLRAALTGTDRPAAVGEAP
GPHGPVRSGDEPIAIVAAAGRWPGGARSPEQLWELLDARVDAIGPFPTDRGWDLTALHDP
DLTRPGTSYTRHGGFLPDAAEFDADFFGISPREATAMDPQQRLLLETSWEALERAGIDPD
ALRGTATGVFAGVTPHDYGPRLVEAPEGYGGYVLTGSLTSVVSGRVAYTLGLEGPAVTVD
TACSSSLVAIHLAAQALRGGECSLALAGGVTVMPTPGMFTEFSRQRGLAPDGRCKPFAAA
ADGTAWAEGVGVVVLERLSDARRLGHHVLAVVRGSAVNSDGASNGLTAPNGPSQQRVIRA
ALTAAGLRPADVDAVEAHGTGTTLGDPIEAQAILATYGTDRPADRPLRLGSLKSNIGHTQ
AAAGVTGVIKLVEALRHGRLPATLHVDAPTPHVDWSAGTVTLLTEPADWPTTPGRPRRAA
VSAFGISGTNAHLILEQAPEDVAEPEPAPPAEDRPAEDRPADGEPAEAATTGADALPWVL
SAHSESALRAQAAQLAEHVAASAGEADRPSAADVGHALATTRALLAHRAVVVGDGPEQHR
AGLLALAAGDSAAHVVVGVAGPAGRTALLFTGQGSQRAGAGRELYAASRVFAAALDEVTA
HLDGAVGRSVGELMFAEPGSAAAEELDATAITQPALFALEVALYRLAESYGLRPDYLIGH
SVGELTAAHLAGVLSLPDAATLVAARGRIMQSVPATGAMAALEGTEEEIGRLLADAAGTI
GIAAVNGPRSVVVSGDRDAVDEIGRRWRDAGHRVRGLRVSHAFHSGHLDPVLAEYREVVA
GVTLHPPTIPVISNVTGRVATDAELTDPDYWVRHLRGTVRFHDGIRTLADLGITTYVELG
PDAVLSALAEQALAEPGSAEPPLTEPVVNESAVNEPVVNESAVHGAVPASDAAVGPAPRV
VALLRANRPEVRSFTTALARLHVDGVAVDWSAAFNGRRPRHTDLPTYPFQRQRYWLDAPT
RTADRAGLGTGAGGPQHPVLTGAVELADGGLVLTGRLDPAALPWLADHAVRDTVLLPGTA
LLDLVLSAARHCGAHRVEELALTAPLALSAAGTLDVQVLVAPVDPAGGGGPDGVERRAVT
VHARPVADQTDPPGPWQRHATGFLRTDDGAAADDRGGADDRGGAWPQPDAVSIDVSGLYP
RLAGDGYQYGPAFRGLRAAWRQGDDVLAEVTLPDAAGARDRFEVHPALLDAALHAVVGLL
PGPDADPGRIRLPFAWQDVTLAARGASSLRVRVSPTGPDTVRLAVDDAAGEPVARIGGLS
LRPVATQVLADAGRAVAGRGAGDAMFRLDWQVVPPAADLADLADLADLADLADLPSLADL
PSLADLADLAALRAEIDAGGHVPALVIHRSAAVGPTGTAPVESPTDEEADPVPAAHATVR
AALHLLQDWLGDERFSGSRLVILTERAVATGPGEDVADLAAAGVWGLVRSARTENPDRVA
LLDVDGRASSRDAVRAALALLAARPAEHSELAVRDGEIRVPVLAPLGTQPALLPPAGTDV
WRLDVTAAGSLDNLALLPEPAAQRPLAPGEVRLALRAAGLNFRDVLIGLGMYPGGARIGA
EGAGIVVEVGAQVSDLAPGDRVMGLVQGTLGPLAVTDRRLLTAIPPGWSFSQAAGVPVAF
LTAYHGLAGLARLRPGESLLVHAATGGVGQAAVQLARHWGVEVFGTASPAKWPVLRGQGL
DDTHIASSRTLDFADSIRAATDGRGVDAVLNSLAGPFTDASLRLLAPGGRFVEMGKTDLR
DPAAVAADLDGGSYQAFDLFEVDPARIGEMLAVLADLFTRGALSPLPTTSWDVRHAPQAL
RQLSLARHTGKLVLTLPAPLDPAGTVLITGTGALAALAARRLVTHHGVRHLVLASRGGPA
SPDAEAVRAVLAEAGATATVVAADVADPDDVRRLVAAVPADHPLTAVVHTAGVLADGVVT
SLDDPTMDRVLRPKVDGAWLLHRATAGLDLAAFVLFSSVAGLLGNGGQGNYAAANAFADA
LAHHRRAAGLPAVSLAWGHWAQAGGMAGQLAPADLARLARTGIAPMSTAQGLALFDLAIG
GGTAAGAQPLLVPARLDPAGAARPAGGGLLRGLVHVPSQRSTAGAGGAVGAGAAGAATPA
GAAGTPPADRAAALVERLRGQGPDEQRRALLTLVRTTAAEILGHASAAAIRPDRGFLESA
FDSLSAIELRNRLARETGVHLPTTLLFDHPTPAILAAHLRDTLFADSRSPDSPSTDSRST
DSRAADSRAADGRAPGEGVPDRQPLDERLALVDLADEADAALLSEQIAGATDDEIFDFID
RELGIS
>A0A2K8QY22|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MANENEEKLLTYLKRVSSDLKQARARLERIEADEREPIAIVSMGCRFPGGVRSPEDLWRL
VAEGRDAISEFPANRGWDVEGLYDPDPGRSGTCNTREGGFVHDADQFDPAFFGISPREAL
AMDPQQRLLLEVSWEAIERAGIDPLSLKGTRAGVYVGLASFQYGGDPRYAPQSVEGHLLI
GNVSSVASGRISYTLGLEGPAITLDTACSSSLVTMHLAAQALRRGECSLALAGGVAVMAT
PGVFVEFSHQRGLAANGRCKSFAAGADGTGWGEGAGMVLLERLSDARRNGHPVLAVLRSS
AINQDGASNGLAAPNGPAQRRVIEAALTAAGLTVDDIDAVEAHGTGTALGDPIEAGALLA
TYGKGRTAGHPLWLGSLKSNIGHTQAAAGVGGVIKTVMALRHATLPRTLHVDQASPAVNW
SSGAVELLTEAREWPERGRPRRAGVSAFGVSGTNAHVILEQAATDREAAEAGETGEAGQD
GQDGEDDAPALDAPALDAPALGGTALGGPAVPWVLSGRSEAALRAQAERLLTHLNERPEV
SPADVGHSLATGRSAFEYRAAVVGADRPQLLAQLAALASGGASAGVVRGEGAAVVEARPV
FVFPGQGSQWVGMAVGLLDSSPVFAGRIAECEVALSGFVDWSLVGVLGDEAALGRVDVVQ
PVLWAVMVSLAEVWRSCGVVPAAVVGHSQGEIAAAVVAGGLSLEDGARVVALRSQAIARG
LAGHGGMMSVSLPVEEVWERIAAWDGRISVAAVNGPGAIVVSGEPDALRELQAECESEGV
RAKLIPVDYASHSAQVEQIHDELLRILAPIRPRTSRTLFHSTVTGEPLDTAGLDAAYWAR
NLRETVRLEEATRALLTGGHRLFVEVSPHPVLAAAMEATVEAADGSAAVIGTLRREEGGP
ERMLLSLAQAYVHGAEADWRGLFAGRGARRVDLPTYAFQRARHWVEPQVGPVAESATGPA
EAEFWSAVENADLDTLTATLGADADAPLSEVLPLLSSWRSRLSDQALLDSWRYRVGWQSL
DEQRPLALPARLLVAVPAEAGPADSGAVDSGAAETGAIETGAAEAGPVATGPVATEAIVA
GLAALGVETVPVRIGADDTDRDRLATRITEALGEAGAPGGVVSLLALDEAPHPEHRDIPT
GFATTLALVRALGDAGIDAPLWCVTRGAVSTGGADRLGAPAQALIWGLGGAVALEHPQRW
GGLIDLPGSLDEGSLRALTRALGGRGGGEQLAIRASGTLARRLRRAGAGRSGERWQPRGT
VLITGGTGGVGAQIARGLADEGAEHMVLVSRRGPRAPGAAELEAELTERGARVTVAACDV
ADREALERLLDSVTGDGVDLPLTAVVHAAGALDDATVDALTPERIEAVLRPKVAGARHLH
ELTRALDLDAFVLISSIAGTVGAAGQGNYAAASAYLDALAQRRRADGLPATSVAWSAWAG
GGMIDGEVADQLRRRGAPPIDGARALELLRQTVAQGDGFLVAADIDWGRFASALSATRPL
PLLADLPEAGGTGQDPAGAEREEAGGAAALRTRLVELSPADRHTALVELVSEQAAAALGY
ADAGAVESGRAFKELGFDSLTAVDLRNRLNAATGLRLPVTLVFDYPTADDLAGLLREELL
PSGGESADVDTAALAELDRVQSTLAALELDDIESATDDEMFELLDGMFELLGRDLTAS
>A0A2K8REQ8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MATAEKLLKSLKLVTAELHDLRQQVARRTDEPVAIVGMACRLPGGVGSPQDLWRLVSEGR
EGVSGFPEGRGWDVEGLFDADPGRAGKSYTDRGGFLHGAGLFDAGFFGISPREALAMDPQ
QRLLLEVSWEALERAGIDPGTLKGSDVGVFSGVITQGYGMRGETPPELGGLVGTGATASV
ASGRVSYVFGFEGPSVSVDTACSSSLVAMHLAAQALRQGECSMALAGGATVMANPSTFVE
FSRQQGLSSDGRCRAFSAAADGTGLAEGAGVVVLELLSEARRNGHQVLAVIRSSAVNQDG
ASNGLTAPNGPSQQRVIRQALASAGLSAADVDVVEGHGTGTVLGDPIEAQALLATYGQDR
EPERPLWLGSLKSNLGHAQAAAGVAGVIKMVEALRHGVMPATLHADTPSSQVDWSAGAVE
LLTEARDWPDTGRPRRAAVSSFGVSGTNAHLILEQAPVEQSAVPVPGESGLVGTDGGVVP
LVLSARGAAGLAGQADRLGSFLSAHTDLDLAEVARSLVSTRGALSDRAVIVAGSRDEALT
GLNALALGHSAAGVVTGPARDPNAAGRVVFVFPGQGAQWAGMGADLLESSSVFATRFDEC
ARALDPLTGWSLMDVAHGAEQAPSLDAVDVVQPLSWAVMVSLAAVWQAAGVVPDAVVGHS
QGEIAAACVAGGLSLDDAARVVVLRSRAIAAGLSGRGGMVSVACDVRRARELLAAWPDRV
EVAAVNGRASVVVAGDPDALSELLAVCETEGVRARRIPVDYASHSAHVEAIEQDLMDTLV
GIRPQPGSVPFYSTVTGGLLDMAALDAGYWYRNLRQTVQFAPVIRSLAAGGHGVFVEVSS
HPVLAPAIEETVEGAAAGPVAVIGTLRREESGPRRVLEALGRLHAHGVAVDWPAVVGRSA
GRPMELPTYAFQQEHFWLAGGAGSNDATALGLGVVDHPLLGAVTSLPGSGGVLFASRWSR
RTHPWLSDHAAGTELVSAEAFVEVLLRAADEVDCGLLAELDVEVPLRLPQRGGVRVHIEI
GEPDESGERRAHVYSRCEDAAEQEGWTRHITALIAPDSGLPDFELTQWPPQGSTAVDVPG
HEGLDAVWIRGGEIFAEVSLPEEAAESGKFCLHPVLLEAAAGARSSTEPAAEYSEPELRT
LWRHVRMHATGASMLRVQVLPGASGTFGLRLADAAGAPVASVAAITVRSISPEELSAVPG
SRGLRDSLFRMEWPESAVSSSGGSAEVRWVSTGADLAALVSAGTPTAVVVADLTDLSGGL
RPVLGQALELVRAWLAEPALDGSRLVVVTPDVSDPVAAAVWGLVRSAQAEHPDRFVLVST
DGTDEGTEAPGRMPVGVLADVHASGEPQVALRSGAVLVPRLARVADTDQASTGRRLDPDG
TALITGGTGALGALVARHLVVEHKIRSLVLVSRRGPDAPGAADLDAELTALGARVRIVAC
DIADREAAGELIASVPQDAPLTAVVHTAGVLDGGVVTALTPERLDAVLRPKADAALVLDE
LTRHLDLAAFVLFSSAAGTFGNPGQGNLAASNAYLDALAVRRRTAGLPATSVAWGVWDQT
GISGDLGVADQRRMARWGLVAHSAQEGLELFDAALRADDAVLVAARLNFAGLRAQAASEP
VHVLLRGLVRAGRRAAQQASSREGGLAGQLAATPPVQREQILLDLVRREVAAVLGYSTPR
KVDPDRAFQDVGFTSVLAVELRNRLAGLAGIRLPASIAFDHPTPRRMMRHLLAELCPEDG
SESADREDEIRRALATTPLSRFRELGLMEQILHLVAHPSGESAAAPDTAEPKQDAGPLIA
EMDVDNLVKRAMEKARKP
>A0A2K8R111|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MDDVHKLRHYLTRVTAELKETRTRLRVAETAAAEPVAIVGMSCRYPGGVASPEALWELVA
AGGDAISGFPADRGWDLAGLVDPDGERPGTSYTAEGGFLHDAGEFDADFFGISPREALAM
DPQQRLLLETSWELFERSGIDPASLRSSRTGVFIGASFHDYGSRLPAIPEEVAGHAMTGV
AGSVVSGRIAYTFGLTGPAVTVDTACSSSLVALHLGVRALRNGECGMAVVGGVAVMSTPD
LFTEFSRQRGLAGDGRCKAFAAAADGMGAAEGVGLLLVERLSDARRNGHQVLGVIRGTAV
NQDGASNGLTAPNGPAQRRVIRDALADAGVAASEVDAIEGHGTGTALGDPIEAQALLATY
GQDRPADRSALLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGMVPRTLHVDEPTPHVDWAS
GAVRLVTENAPWPGAERARRAAVSSFGVSGTNAHVILEAAPPAETVSEESAPTEGVLPWV
ISARSEAALRAQAAQLRTYAATGDRHLADIGWTLARHRAALEHRAVVIATDRDTFLTGLD
AIASGEPATHVTSGTAPEEPPSGPVFVFPGQGSQWVGMAAELLATSPVFAESIGQCAQAL
APHIDWDLLDVLRETSDETALERVDVVQPALWAVMVSLAQVWRSLGIEPAAVIGHSQGEI
AAACVAGALSLEDGAQLVALRSRLIAEELAGHGGMVSLATSADQTLDLLTGHDEVWIAAV
NGPTTTVIAGTPAGLAEVTAAAGTAGLRPRTIPVDYASHTPHVERIREQLRQLAAPITPR
AGDVPMYSTVTAAPIDGEALDAEYWYRNLREHVRFHHTLQALQADGHALFLETSPHPVLT
TAIEEADAHATGTLRRDHGGIRQLHTSLATLWTHGLTPDWSALLTPNTPTPADIPTYPFQ
RRHYWLSAADRVGDLAGAGLSVVGHPLVAAGVSMAEGGGFVCTGRISTRTHPWLADHTVL
DRVLVPAAALLELVLGAGQHMGAERLDELVLHTPLTVPSDDTALDIQVGIDAADERGTYA
VRLHSRPHRPERDDDPADWVCHATGTLTASAAPGDELMDAEPEAQWPPTGAVPVDIDAFY
ERLADHGYGYGPVFRGVRAVWRRGEEMFAEVRLPESAAGDAGRFGVHPALVDAALQTRLV
ALLDGDSERMMPLSFSGARLHATGATVARVRTSPTSPTSPTGPAGPGGISLRMTDLAGLP
ILTVDELVSRPLAADALTAAAGAVPDGLFEVVWTPLDLRPSEATEDTVVLGASLPGVDAP
VHPDVAALVAAVRSGAPLPPLVVLPAPPAPDGVTDVPAASRERLAAVLGTVREWLNHPEL
DAVRLALVTRGAVAAFPGERADLVSAGVRGLWRSVCSEHPGRFAQVDLDGAPESAATLPA
ALATGEPELVVRAGAVSVPRLGRVAPSDAVPEEARAWSLDLEDTGGTVEGLRLVPAPVVE
GPLAPGQVRIAVRATGVNFRDVLASLGVVPGGEGLFAAEGAGVVLEVGPGVDGLAVGDRV
MGLVSGAYAGPVAVADARMVVRMPGGWTYPQAASVPAAFLTAYYALVELARVRAGESLLV
HAAAGGVGMAAVRLARHLGVEVYATASEPKWPVVHGMGIPAGRVASSRTLEFADRFLTAT
DGRGVDVVLNCLAGEFVDASLALLPRGGRFIEMGKTDVRDADEVAAGWPGVGYRAFDLGE
AGAERLGAMLAHLAGLFEAGVLSPLPVTAWDTRRAREAFRHIGQARHTGKVVLTPPRETI
DGTVLITGGTGVIGSAVARRLVIGHGVTDLILVGRRGPDAPGAPELIAELAESGATARVV
ACDVSDRAALATLLDGLPRLRGVVHAAGALDDGVVSALTPERLDIVLRPKADAAWYLHEL
TRDRDLALFVLFSSAAGVLGSAGQGNYAAANAFLDALARHRRDQGLPAHALAWGLWGERG
GMTGGLGATDLDRMRRLGMRPLTAEQGLALFDAAIRAPRALSVPVRLDMAALRRHGEPAP
LLRGLVRTTVRRGAANTATGGGGLRDRLATLPPADREHTLSDLVRTHAAVVLGHADGDPV
AGDRSFRDLGFDSLTAVELRNRLGTATGLRLPVTTVFDHPTVAALVAELLRLLVPDGEAT
AARPAVPDRVATAAHDDDPIAIVGMSCRFPGGVRSPEELWRLLTEGRDAIGPFPDDRGWH
AELSRPGGSGGSGDYTPAGGFLYDAADFDAEFFGISPREALATDPQQRLLLETTWEAFEH
AGIDPTALRTTPTGIFAGLTYHDYATRFPEQLADGFEGYLGNGSAGSVATGRVAYALGLE
GPAITVDTACSSSLVALHLAARAVRQGECSLAVAGGVTVMSTPRPIVEFSRVGGLAPDGR
SKAFAAEADGMGFAEGVGMLVVERLSDARRHGHRVLALLRGSALNQDGASNGLTAPSGPA
QQRVIRQALTNAGLTAADVDVVEAHGTGTPLGDPIEAQALLATYGRDRPADRPVVLGSVK
SNIGHTQAAAGVAGVIKMVLALRHGVVPRTLYTEHPTEQVDWTAGALRLAAESEPWPTAG
GPRRGAVSSFGISGTNAHVILEEAPDNGTPDESTPVAVTVPWTLSAKTADSLRDQARRLL
ERLAADPDLAPVDVARSLLSRAVFGHRAVVIGRTREDFLDRLAALGRGEPATGVVRGVSA
DRSGPVFVFPGQGSQWAGMAAELLDASPVFAESFAACADALAPYVEWSPLDVVRGRPGAP
SLDRVDVVQPVLWAVMVSLARVWRSHGVEPAAVVGHSQGELAAACVAGVLSLEDAARLVA
LRSRLIGGELAGRGGMVSLPRPVDEAESLVAPWGERICVATVNGPASTVVAGDAAALDEL
MAACERDGVRARRVPVDYASHTPQVERLRTRLLELAAPIAPCPGGLPMYLTVTGALLDGA
SADAEYWYRNLREIVRFEQATRALADAGHTVFIEVSPHPVLIPGIEQTVERTPRNTPAAR
DAVAVGTLRRDEGGRERLLTALAELFVAGGAVEWSTAVEGGRPVDLPTYAFRARRYWLDA
PEHTGDAGGAGLTAVDHPLLAGAVAPAGGDTVLFTARLSQTTHRWLADHAVLGGVVLPGS
VFLDWALYAGRAVGCPYLPELTLQEPLFLSATDAAQLQIQVGGPDAEGRRELTAHSRPES
AAGDTATGWTCHVRALVAPDPVGSDGGPAGVPVSGEHGSGAAAFAELAAAWPPPGARAVD
LTGHYDRLAADGFDYGPAFRGLRSAWRRDGHVFAEVALDERPEGTGSGPVDGFALHPALL
DAALHAVGLGGFFDPAESAGGRIRMPFSWSGVRLHSTPGVTPGATPSATSPATVRVRLSA
VGPDAIGVHLTGVDGQPLAHIGELTLRPVSVDRLQTAAEERVARPVRRERPRPRPQDTAA
AQRVLDAAPMERERLLADLVREQLSAVLHHEAGADLGPDTEFLALGMDSVRGIDLRDRLA
TLLGLRLSATATFEHSTVDRLAGHLATLLDSRAATRPSAPVAEDTAPPERAAPERSAPET
APGPSPDTAPDTAPDTASDASAPPSAVELELAKATAAPASDPYDSLTTLYHQAYASGRAQ
SVGMALIQAAGRLRPSFTAEDAAGHVLPPVKMAGGDGTRATLVCLPAITATAGPIQYGMM
AQMFEGRRDVLSLVNPGYLEGELVADSFDALIELHLHQLRAAIGTERYVLVGHSMGGLLA
YALAERAERAGLPPGAVVLLDTFEAAHQFSEKTHIALNEGLDSREQLLGDFALTGAKLSA
SGRYNALLMEECVLRPVKGPTFFLSAAEPMPHQDEGFEGDAWRASWPFPHTAKATPGDHF
TIMEHHLPRTTEAIEGWLAERGL
>A0A2K8RL62|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MSHTPDHTPLPWLLSADSAHALREKARRLDAYLRDREPDLDEVGHWLRGHAAIEGPHRAA
VDSRERTRLLEGVAALAGGGRSNGLSTGRGEPGDIAFVFPGAGSQWPGMAAGLLDSSPVF
RARMDDCAQALEPHVGWSLIDVARDPGAGAELARADVVQPVLFAVMVSLAELWRAHGVTP
SAVVGHSLGEVAAAAVSEALSLDDAARVAALWSRAQSSLAGRGDMVSVRASADEVRERLA
AWGGELVLAADNGPATVLVSGGTAAAAELIEALAADGVSARRTSVGLAAHSPQMEEVLPR
IRADLAGLRPRRPRLPFHSSLTAGEVTGPELDAEYWCDNIRRPVRFQQTVRGLLASGRQV
LLEVSPHPVLTSAMQDIIEHHRAAGSVVATLRRHHGGPDRLTAALGELWAAGARADWPSV
PAGPSPAGLSELLDRPVPETDEPAADAPTDTAAALAALPDGRRRTALMDLVCAEVAAVLG
RDRLEPPERRRPFLELGLDSVTAMEVRNRVTQATGLPLPAAAVFDHPSPVLLAEHLVTVL
TPAAPPASGAGRDRRPAAADEPVAIVGMGCRLPGGVRGPEDLWRLLDEGRDAVAALPADR
GWDTVEAYDARPRTPGRYYQREAGLLQDAPLFDAEFFGVSPREALAMDPQQRLLLETSWE
ALEAAGIRPDTLHGSRTGVFTGLMTLGYGPSLDDGSDLAGHVLTGTTGSVASGRVAYTLG
LQGPAVTVDTACSSSLVALHLAAQSLRSGESDLALAGGVTVMPGLGMFLEFSQLGALAPD
GRCKAFADTADGFGLAEGAGVLVLQRLSDARAQGRRVLAVVRGSAVNQDGASSGLTAPNG
PAQQRVIREALAAAGLAARDIDAVEAHGTGTTLGDLIEADALLATYGQDRDGRPPLRLGS
LKSNIGHTQAAAGVAGVIKTVLAMRHGSLPRTLHVDRPSSRVDWGQGQLELLTRQTAWPE
TDRPLRAGVSSFGISGTNAHVILESAAPEPAAPRHTPADALPGLSAEAVPWVLSGKTRQA
VRDQAARLLGRLEAGPTPDGADIGWSLVSTRAAFEYRAAVVGTGRDELLTGLRALATGEA
AAHLTEGRADDAARVAFVFPGQGAQWAGMARPLLDTSPVFARAMAECAAALTPFVDWSLL
DVVDDAAALERVDVVQPVLWAVMVSLAELWRSYGVEPAAVAGHSQGEIAAACVAGVLSLQ
DGARVVALRSQAVAESLAGLGGMVALPLSEEAATDLLGRWAGRLSLAAVNGPSSTVVSGE
APAVDELLAACGTAGIRARRIPVDYASHSPQVERIRDRLLADLAPVTPGAASIPAYSCTT
GEQADTRMWDARHWYRNLRETVRFDSASRALVDAGVSVVLEVSPHPVLVAALQETLEAAL
PARPGRTALGTLRRDDGGPRRFLLSLAQLHTLGVGVRWEAVFGGAREVELPTYAFQHRRF
WPEAGAEQRSDALDTEFWATVERADLGAVAAALGVADETLAPVLPALSSWRARRAEKSTV
DQWHYRETWTPLRITGRLSGSWLLVVDDAASEDPWTSAVTGAFAERAAVLRVQEPDRARL
ARELAALSTTDCAGVVVLVPDGVAGVVFVLVVLQAVLDAGLGVRVWAVTRGAVSVGVGDG
DGVGFPVQGGVWGLGRVAALEHPGVWGGVVDVPGVVDEGVVGLLGGVVGGGGGEDQVAVR
GSGVFGRRLVRAGRFDGVGVGVGGGGWSTSGTALVTGGTGGLGVCVARWLVGCGAEHVVL
VSRRGAGAVGVEGVRAELEGLGARVSVVACDVADRDGLAGVIAGIGEEVPLRTVVHAAGV
VDDVPLASLTPRQLEADLRGKVDGAWHLDALTAGMELDAFVLFSSGAAAWGSGGQAGYAA
ANACLDSLAAHRRARGRTATSIAWGAWDESGLVAAQPGRRHRLSRLGVMPMRPALAVAAL
QRVLDGDETAAVITDTDWSRFAPAFTASRPSPLLSALPEAVRALESAPREPDVSGAPAAG
ASARRLAGLPEQARRAALSDLVRHSAAAVLGHAPGTRIDADQAFRELGFDSMTAVELRGR
LVDATGLALPTTVVFDYPTAARLTDHLASLLAGTPATGGTPLPSPVPAADDPVVIVGMAC
RYPGGVTGPADLWRLVSEGTDATGDFPADRGWDLAALYDPEGTRPGTTITRRGGFLDGAG
DFDPAFFGISPREALAMDPQQRLLLESSWEALEHAGIDPESLAGSPAGVFVGAYPSGYQA
AVGRLGDEVRGFALTGGSSSVVSGRVAYVLGLEGPAVTVDTACSSSLVAMHLAAQSLRSG
ECTLALAGGVTVMADADAFVLFSEQGGLAPDGRCKPFADAADGTGFAEGVGTVVLEKLSD
ARRNGHRILAVLRSSAVNQDGASNGLSAPNGPAQQRVIRQALAAAGLAARDIDAVEAHGT
GTTLGDPIEAHAVLATYGQDRSGEAPLWLGSLKSNLGHTQAAAGVGGVIKMVLAMRHGVL
PRTLHVDAPSSQVDWERGRVALLTEATAWPEIGRPRRAGVSSFGVSGTNAHVILESAPAD
DPVSAAPPLAPRVVPWTVSGRTPEAVRAQAARLSARVAADPSLDVADVGWSLLATRPALG
HRATVLGAGRDELLAGLRGLAAGETAGAVILGEARPDRVVGVLFTGQGAQRLGMGRELYA
GSPVFAAAYDAVVAELDAHLERPLKDVVWGDDAGSLDRTGWAQPALFALEVALFRLLESW
GVVPDALLGHSVGEVAAAHVAGVLSLPDACRLVAARAQLMEALPPGGAMVAVEATEAEAA
PLVTRGVSIAAVNTPGSVVLSGEEAAVTGAAESLAALGRRTSRLRASHAFHSALMDPMLA
EFERVLETLVYREPRIPVVSGLTGAVATGGELRSPAYWAAQAREAVRFADGIQCLADRGA
SALVEMGPDAVLSALAEDGCAEGTLRVPLLRRDRDENIAVTAGWAALHAHGVPVDRGAVL
PEGRRIDLPTYAFQHRRFWPAPVAASGVESWRYRETWTPLAPPDRATGGSYLLVIPAGLD
GEPGTAAVAEALGPRTVTLTVDGDPDRAALAGRLPEAADCGLVGVVVLVPDGVAGVVFVL
VVLQAVLDAGLGVRVWAVTRGAVSVGVGDGDGVGFPVQGGVWGLGRVAALEHPGVWGGVV
DVPGVVDEGVVGLLGGVVGGGGGEDQVAVRGSGVFGRRLVRAGRFDGVGVGVGGGGWSTS
GTALVTGGTGGLGVCVARWLVGCGAEHVVLVSRRGAGAVGVEGVRAELEGLGARVSVVAC
DVADRDGLAGVIAGIGEEVPLRTVVHAAGVNTGTVALESLTRERLDEELAVKVDGAWHLD
ALTAGMELDAFVLFSSGAAAWGSGGQAGYAAANACLDSLAAHRRARGRTATSIAWGAWSG
AGMVGATPGQDALLRRLGVVPMRPDLAVSALQQALDDDETAIVVADLDWPRFLPTFTATR
PSPLLSALPEAARPAAPAEEESPAGDPGLSARLVDLSARERSVFLVELVLREAAEVLGHT
SGQAIVADQTFRDIGFDSFTAVELRDRIARTTGLTLPATTVFDHPSALRLAAHLGSLLDG
TGTNEDTAAPGAPVGPAADDPVVIVGMACRYPGGVTGPEDLWRLIAEGTDAITPFPADRG
WDLAALSAPGGSGFSTTRSGGFLHDAGGFDADFFGISPREALTMDPQQRLLLETSWEALE
RAGIDPRATRGSRTGVFAGVTDQGYGPPLHQPAEDGDPYALTGTAASVASGRVSYVLGLE
GPALSVDTACSSSLVAMHLAAQSLRRDECSLALAGGVTVMATPGPFVAFTRQGGLSPDGR
CKSFSQEADGTGWSEGVGMLVLERQSDARRNGHRILAVLRGSAVNQDGASNGLTAPNGLA
QERVIRQALADAGLRPAEVAAVEAHGTGTRLGDPIEGRALLATYGQDRPGEEPLWLGSLK
SNIGHAQAAAGVGGVIKMVKAMEHGVLPRTLHADRPSSEVDWAAGAVRLLAEARPWDGPR
RAGVSSFGISGTNAHLILEAGPDTSVSAERRPGADGPRGPVPWMVSGHTEGALRDQARAL
LDRTGEADVHDIGLSLATTRALLHHRAVVVARDAEGFRAGLAALAAGDQAQPVVTTPPAP
GGLGFLFSGQGAQLPGMGQELAAAFPAFASAFAEASAGVGGVRVDDAEVLRGTAMAQRAL
FAFQVALYRLWESWGVVPDAVIGHSVGEVAAAHVAGVLSLEDACRLVAARADLMERLAER
GGVMMSVRASEDEVTGTLADGVSLAAVNGPRSVVLSGDAEAVEAYAARWPGARGLRVSHA
FHSHHMDGMLDAFAAVVRELTFHPPSLPMPAAGDVTDPDHWVRQVREPVRFLDGVRQLLA
RGVRTFCEIGPDAVLTGLGEECADDVPGVRFVPSARRGSPEQVRTVRALGELAAHGVTPR
WDRVFPGARPTDLPTYAFQRRRYWLGPRQPDGDFWALVRQRDLSALTESLRVDGDPRLSE
VLPALARWHRRGEDSAALGRWRYELTWHPVAADPPAEVTGTWLVAPATAGDPLADAVAMA
LAERGADPAVVRPEDVPAQVARRPVAGVVVLLPAADGPDEADGGSPAVPGLDEAAATVEL
VRRIAAEETGAPLWFVTRGAVAVDGEVPLSGPGHSLLWGLGPVLRDERPELWGGVVDVPA
EPSATAAELLVTALTSGWDQLAVTDGGLRTRRLVRAPYDRTVWRPSGTVLVTGGTGALGR
HVARWLAAEGAGHVVLAGRRGGDAPGVAELCAELTAGGVTATAVSCDIRDRAALAELLDR
CSPDAVVHAAAVVDDTTLDGLTPHRVDQVLRTKALPAWHLHQLTRDRPLSAFVLFSSVAG
TLGTAGQGNYAPGNAFLDALAAHRHALGLPATSIAWGPWAGDGLAAADAVAGAAGRHGFT
PMDPALAVRALAATEVPFALVMDADWERFPAERASSVVAGLVPDRAAEPAPGLLDRLSGL
SEAEQARLVRQTVRSALAAVLGHRDPGTLGEDRTLTELGLDSMTAVELRNRLRAQTGLHL
SATLAYNHPTAEELARHLHDRLRERTAPAASSVTAELDRLEAAVAALPPGGDERGAVAER
LRALLGEIAPDPAHERDLDDVTQDELLALIDDEFGR
>A0A2K8RJD3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MANEERLVEYLKRVTSDLREARRQLSARSEPVAIVGMACRFPGAVGSPGQLWDLVAGEVD
ALSDVPAGRAWDLESLYDADPDAPGRSYVRAGGFVTEAAGFDADFFGISPREATAMDPQQ
RLLLETSWEALERATVVPGSLRGAQVGVFVGTNGQDYGRLPLPDGLEGYVGTGSSASVMS
GRIAYTLGLTGPAVTVDTACSSSLVALHLAAHALRQDECELALVGGVTVMSTPQAFVGLS
RQRALSADGRCKAFAEAADGTGWGEGAATLVVERLSDARRLGHPVLAVVRGSAVNQDGAS
NGLTAPNGPAQERVIRAALAQAGLRASDVDAVEAHGTGTRLGDPIEAEALLATYGQERDR
PLWLGSVKSNIGHTQAAAGLAGVIKTVLAMRHGLLPRTLHVDAPTSHVDWTTGRVELLTK
ARPWPKADVPRRAGVSSFGISGTNAHVIIEEPTEPPAEEAPVGRPAHGPVPWVLTARGNT
ALREQARNISALADRHAPGDIGHALATTRAALTDRAVVVAETAEEFRTALSALAEGSVPQ
NVVCGTVGQVGRTVFVFPGQGAQWVGMAVELLESSAVFAARFAECERALSPFVDWSLTDV
VRAGDFGRVDVVQPVLWAVMVSLAALWESVGVCPDAVVGHSQGEIAAAVVAGALSLEDGA
RVVALRSKAITGLVGGGGMVSVPLPVDEVRSLLPEGVSVAAVNGPFSVVVSGDVAGLEQV
LGVVERARRIPVDYASHSVWVEEIREDVLRACEGISPRSATVPFYSTVDGEWVTGDELDA
GYWYRNLRQTVEFEAGVRALADAEFTTFVEVSTHPVLTVGIEDSAPGAVVVGTLRRDQGG
RDRLLRSAAELFVQGVPVEWSSLLPDARPVELPTYPFQHASYWLDGVPGRSGDVGALGLA
AGGHPLLGALVDLGDEGCVWTGRPASGAHPWLADHAVAGSVFLPGTAVVELAVSAGRRTG
YPRLAELTQYTPCVLPDRDGVTLQVRLGPETEGARPVAVLSRRGEDDDWTRHADGLLTAG
GPLPDDGELAAWPPPGAAPVDTTDLYRRLDEAGYGYGPAFQGLRAAWRLGDTLYAEVAAP
GGADSGGFLVHPAALDAALHALFLDRDLDGIQVPFSWSGVDLSPAGPGALRVRLSVPGPD
EASVLIADDTGRPVCSVDRFVGRPLSAGQLAAGRTGAADRLFRPGWTPVPARASATPAPV
LLGPDLDLSAVTGAPDVVVAAVGVAPGHEEDPVGAAHETVRRFLTLLQDWLADDRFASSC
LVVLTRPGDLAAGAVQGLVRSAQSEHPGRFVLLEADGPDAVPAALASGEPHVAVRGDQVL
APRLARVTRGVEKSCLAPGGTVLITGATGLLGGLVARHLVREHGVRHLLLLGRRGRVAAL
DDLDAEVTWAACDVSDRTALADVLAAVPAEHPLTAVVHMAGVLDDATVLSLTPERIGPVL
APKADGAWHLHELTKDLGLAAFVLFSSTAGLLGSPGQGNYAAANGFLDALARHRRAAGLP
AQSIAWGLWQDPSAMTGHLTAADIAGRMGRSGVLPLTAEAGLALFDAALTVDAPVLAAVR
IDPARLPDAAPPLLRTLAEGGAAGTSRPRPPAGAGDWAEGFLRLPEDERERGILALVLAE
VATVLGHDARRVDPQRAFKDFGFDSLTAVDLRNRLSAVTGIRLPATLVFDHPSPRMLSKW
LGEQLERNAPADPPEAARTVPRTPADEPVAIIGMACRFPGGVTSAEQLWDLVLAGGEAIT
PFPQDRGWDLDALFGTGPDRPGRSHTRHGGFLDDVSGFDPEFFGISAREALAMDPQQRLL
LEAAWEALEDAGIDPAGLRGSPTGVFAGVMHHDYAERLRDAPPEIEPYVGNGSAGSIASG
RVAYTFGFEGPALSVDTACSSSLVALHLAARALRAGECSLALAGGVSVMATPELFVQYSR
QRGLSEDGRCRAFADSADGTGFAEGVGMLLVERLSDARRNGHRVLAVVRGSAVNQDGASN
GLTAPNGPSQERVIRAALADAGLRTGDVDVVEAHGTGTRLGDPIEARALLATYGRDRPAD
RPLWLGSVKSNIGHTQAAAGAAGIIKMVMAMRHNTIPRTLHADTPTSRVDWDAGAVRLLS
ETRPWQGPRRVGVSSFGASGTNAHIILEGATPDAAAGESAQRPRRPAPDGAAGLPLALPL
AAHGPAALRGQAGNLLPALARHDPRDVAHSLATTRTTFPHRAVVLGGDPRELRRALDALH
QGEPDGSLVTGEAVADPRPVFVFPGQGGQWTGMALELLDHSPEFADRMAQCARALAPYLD
CGLDDVLRRAEYDRVDLVQPALWAVMVSLAEVWRAHGVEPVAVLGHSQGEIAAAVVAGAL
SLEDGARVVALRSRELAALAGHGGMVSLPLPVADVRDLLKHWPDRLDVAAVNGPRSTVVS
GDADALMELLAHDERARAIPVDYASHSRHVEPLRARILDALSGIAPCTAGIPLLSTVDGD
WPDTAGLGPEYWYRNLRQPVEFEAATRTLLDRPGTVFIEISPHPTLVVPIRETAEQAGTP
VPVLSTLRRDDGGPRRLALALADAHVHGLPARLPVPRGHRVDLPRYAFQRERYWPEPPRE
RADVAGAGLAPANHPLLGAAVDLDEDGCVLTGRISLATHPWLADHTALGVVLLPGTALLD
LAVSAGRRVGHGRIAELTLTAPLTLPATGAVRLRVRVGSAGPDGRPVTVSSCPEESADWT
RNAEGTLAPEQPLTGALAAWPPAGAESVDVAALYDTYARAGLDYGPAFRGLRAAWRRGDE
VYAEVAHDGLPREEFGVHPALLDAAVQAMAVHDRREALCLPFTWRDVTLSGEAPTALRVR
IAPAGENAVSLEAADSAGNAVASVGSLTVREVPAAALPGAAPVADSLLRRTWTDLTTPSG
SPRRWVAVGEGASALAAALPGARTADTLEALLGQGDLPDTIVVSPRCDGPDPARAAHRAT
ARALALLGAHLAAPGLTDTRMVLLLPRDDLAAAAVAGLVRSAQTEHPDRLVLVHCDPADP
VDLALVPAAVASGEPELAVASGRLRAPRLVPAVPAPERPALDSSGTVLVTGAGGALGTLV
TRHLVQAYGARHLLLVGRTAPVVPEGLDADIRAVACDVADRTATAALLRTIDTAHPLTAV
FHTAGVLDDATMTTLTEDRLHPVLAPKVDGAWNLHELCGDVGLFVLYSSVAGLLGAPGQG
NYAAANAFLDALALHRRNLGLAAQSLAWGWWAETSGLTAALGDDGRARLTGAGVVPMSSE
GGLALLDAALACGDALLAPLRLDRAVARGLDRPLLRDLLGGRRRTHTPGAGAAGPEERLA
RATGRERGRLLLDLVRRRAAALLGRTEVHPARGFLELGFDSLTAVELRNQLSTATGLSLP
TTLTFDHPSPVALAEHLDALLEARDPTRPDGLLTTLSELEHLAGSLPPDDADHGELRSRL
AALLASLPDAPRDEPPRETGSETSDLDRAGLAEMLAIIDNELE
>A0A5B7USA0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MRQIAVVGLACRFPGASDGHEFWQVLRTGTDAIREAPDDRWRGAGLPHRLGGFVDGIDRF
DASFFGVSPREAAAMDPQQRLMLELSWEALEDAGIVPATLGGGDTGVFVGVMYDDYAALQ
DRLGEAGIGRHTMTGTRRGIIANRVSHHLGLRGPSLAVDTAQSSSLVAVHMACESLRRGE
CGVAIAGGVNLNVLAETTLGAARFGGLSPDGRCFTFDERANGFVRGEGGGVLVLKPLADA
LADGDDVYCVLNGGAMNNDGAGEGDHAGLTVPSASAQEEVVRQAYRRAGVALRGVQYVEL
HGSGTRVGDPIEAAALGAALGHARQPDAPLAVGSVKSNIGHLEGAGGIAGLLKVVLSIHH
RQLPPSLHFTAPPADIPLDELRLRVQTELTPWPEPDKLLVAGVSSFGMGGTNCHLVVSEP
PTADAATGPATAPTAAPAAEERPAPAALAWPLSARTPEALRAQAAQLLSFADARAAVPAA
DIGLSLATTRTAFRHRAVVTGGDRAELRARLAAFASGTAVAGVVEGQATAAGKTVFVFPG
QGSQWAGMAVGLLESVPEFAASMRACEEAFAPYVDWSLDEVLRDAAALERVDVVQPALFA
VMVSLAAAWRSCGVEPAAVVGHSQGEIAAACVAGALSLEDAARVVTLRSRAVLALSGRGG
MVSVLRSAAEVRDRIAAWDGAVSIAAANGPSSVVLSGDADALDRLVERWTAEGVETRRIA
VDYASHSAHVEQIEERLHTVLEGIRPRTSAVPFYSTVTGGLLDTAELDAAYWYRNLRRTV
ELERATEALVRDGHGVFVECSPHPVLVPPLRETVERAGVASAVVTGSLRRGEGGPERFLT
SLAELHARGAEVDWPRVFALRGARTLRLPTYAFQRERYWLAEATARPAAPDVPEALGAEP
PTAAAVAAPALPAGPGLLALVRSTVAVVLGHADGDAVEPGTTFKELGFDSLSLVELRDRL
SAATGLALPAGTLFGHPTPARLADHLRTLTPAGERTTDARPPAASAPAAVAAADEPIAIV
GMACRLPGGVASPEDLWRLVLDGTDAISEFPANRGWDTERLYDPDPDRAGTSYARHGGFL
HDADQFDPEFFGISPREALAMDPQQRLLLETSWEALERAGLDPAGQRGASVGVFVGAMAQ
DYGPRLHAAHAESDGYRLTGSTISVASGRIAYTLGLQGPAVTVDTACSSSLVALHLAAQA
LRAGECSLALAGGVAVMSTPGMFVEFSRQRGLSGDGRCKAFAAGADGTGWAEGAGTVVLE
RLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGVAQERVIRQALAGAGMSPADVDVIE
AHGTGTTLGDPIEADALAATYGRGRAPERPLLLGSLKSNIGHTQAAAGVAGVIKMVQALR
HGTVPRTLHVDEPTPHVDWAAGGLELVTEARRWPETGRARRAGVSSFGISGTNAHVIIEQ
APQEQEQEQEQAARPPSARPEPGPALPWVLSASAPDALADQAAALLSFLDTHPGLDPVDA
GFALAAARSGLPHRAAVVAADLPARRRGLAALAEGSDAPGVVRGTAREPGGIVFVFPGQG
SQWAGMAVELLDAAPVFAASMRACAEALAPHVDWDLFEVLRDAAALERVDVVQPALFAVM
VSLAALWRSYGVEPAAVVGHSQGEIAAACVAGALGLADAAKVVALRSKAILALSGTGGMV
SVALSEDAAAERLRPWDGRISVAVVNGPGAVVVAGALDALDELVASCEADGVRVKRLPVD
YASHSAPVERIADDLAALLTGLTPRPAAIPFYSTVTADALDTTALDGAYWYRNLRQQVRF
AETVGVLAERGHSVFVEVSPHPALTTAVEDLVDHAVAVGSLRRDDGGQERFLTSLAEAYA
RGVRPDWRAVFPGARPVDVPTSAFRRRRYWLEPARTDAAADVTAAGLAAADHPLLGAVVE
LPDSGGVVLTGQLSARTQTWLADHGLGDTVVLPGAAFAELAIRAGDEVGCDQVADLTCEV
PLVLPPHGAVAVRVTVGDEDEYGRRALAVHARPADGSGGWTRHASGLLASGPAEEFDLSA
WPPPGAVAVDWDGGYDRWTELGYRYGPAFQGLRSWWRRGAETFAEVALPEEVAADAGRFG
LHPALLDAALHAAVGDGPDCRLPFSWQGVSLRATGAAALRVWITPDGPDTLALRLADASG
APVASVEALALRPMPAGELTAGPPDALFRVDWTEARVPEAPEAAPAWAAVGTDDLATGAP
LHAGLGALAAAGSVPDTVLAPLTEADAHAVAGRALSLIQEWLADERFASSKLVLVTRGAV
AADAPRRGAGNCATSHDEPAPEHRPTMAGATAWGLVRTAQREHPDRFAVIDLDAHAASTA
ALSTALAAAEPQLALREGRLLVPRLARATGLPTARPDLARGTVLVTGATGTLGGLFARHL
VTRYGATRLLLTSRRGPDAPGAAELAAELTELGADVTVAACDVADRDALAALLAAVPADR
PLTGVVHAAGLLDDSVLEAMRPEQLGRVLRPKVDAALNLHELTLGLDLSMFVLFSSVAGI
LGLPGQANYAAANAFLDALAQHRAARGLPGVSLAWGLWAEASGMTGHLADADLSRMRRAG
LAPLTSAEGLALFDTAVSSAAPLLVPARLDPAAVRAQGAVPALLRGLVRERVRRAAAATG
GPGGPAPLGERLAALSAEERAEALLTLVREHTATVLAHGEPGGVDPGRTFKELGFDSLTA
VELRNRLGTATGLRLRATLVFDYPTPSALAAHICAALGPAAPAVPEPAEEATAAPESAPP
GGELDGLELAELFDLIDGELGTS
>B8MT30|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MTTMATELFLCGPQAALPSPQELSQLRRILLDQENFRESLTSILEDLPNLYEQLTAFDST
TKAVPAASSIEFPLQWLESGTLCVPVDDLLNVGCLPFAVLLQIALFLRHLTENKIGPDFR
QKIQSLQQYGVQSFCTGFLTAAAIAFSGNEEQLVKNTATSLRLAMCIGAYIDQNALNDDN
SSLPCALSVRWKEGQFSKSQVEGLLAHYAHAYIACITDVCCVTVIVQARDEEQLTEKLRK
AGIRAKSVGIKGRFHSASDHAIAVQTLKKFTQSVKADWYTTVRKTFDTHPTGCAKVTVFA
FEEGVLPISLWRRNGSTYGVNGVNNSNSISSVNNINGINDNTEVKYPPHSVAVVGMSCRF
PGAADVNDFWKLLESGTSMVREVPPDRFNVNNHRLAGYQNTKFWGNFLNDVDSFDHRFFK
KSAREAVSWDPEKRILLEVVYEALESAGYFGPGSQDRPNDYGCYIGAVGNNYYDNVACHP
PNAYSMLGTSRAFFSGRISHQFGFTGPAMSIDTACSSSRVAINTACRAIHPFDYQNLAAA
GFLSPSGACKPFDGSADGYCRGEGVAAVVLKSLSTAIEEGDHILGVIVGSAVNQNYNDAH
IIVPCSSSQTTIYKKVLTMANASSSSVTYVEAHGTGTQVGDPIECQSIRDVFGGPHREEI
LYFGSVKGNIGHTEASAGVAGLIKVLLMMQHNTILGQAGFTNLNPKIPALEPDMMAIART
LPWKTLSKLACINSYGAAGSNAVVAIHEPKSVSSVRLGQRRNITSKLPFFISASTEGSLI
AYAEKLLSYVEAQETSARSSSSSLTDILFNLADRVNHTLVYSTAKAVNNLADLKMLLKNV
ITGFEKPLKGASSNPRPVVMVFGGQENDFVGLSEEAVENSGLFKRHLDECDFESRLLGCR
SLYPAIYQRESIRDLPRLHAALFAVQHASAMAWINSGMHVSSVVGHSFEKGSMISVQSDY
ATIKSILHNFNTEVPSNRLEFACFNHPTNHVLVGTSEAVEAFKSYTASDDRLQRSLHLKC
LKVTHGFHSVLAEKILLELEVLANNVQWNKPIIPIELTTEKHVDQEIGPWLIPHHMRNPV
YFSSAVRRVAKKLSSCIWVEAGQGSSIMSLVKNCLNSGNQQQICCPSFLNRPNAVSSLAE
TVVELWKTGVHVRFWPYHRSERHHFEYKSLPPYQFEKTKHWLSFTDKPVLEPTPDITHAT
PAKVTHEFFSFLGFSDPSEKEAVFLIDPESDRYMYLLNGHIASNQALAPASLYVELLSRA
AIILTSNTSYETHVMNMSSMQMKVKLTRITPNVDSWDFEFSSKSKQENGDVQVHVTGKVG
LNRRDDPLLSDTIMQWSALIGYKKCLSIMNMEDGEKMQGRHIYQALQKLILFDEMYQGIK
SISYHGHEAAGKVAAKLDPKLSPNEALYDTPTIDGMMQFAGVLVNYFAHPSGKDVLLCQG
INRIVTGGAFDITAGEWIAYSLLTEDNQERTVSDVYIFDKKLQKVVIAFIGFVFTRISVS
SLQRSLRNVNTGGPGTDPTPVPARATPILDTRISGASASDCAKSSRAPQVLELLHNVTDV
PINEISPDTTLEELGIDSLLVTEVLNEIQSAFGLEIDLNTFLFLPNVKAVCDHINSVLEV
SAGTSTKSAAQIADSTPSLQRAQKVFANCKDAYERAAIQTGAVGFWKKCYPRQAALVLAY
VIEAFAKLGCDMATLQARDVASVIPHSPRHSKLVRQLYRVLEDAGLITFNEQGQFVRTTK
VVDSTPASTIFAQIISEFPLHASVHKIVGVVGEELAECLTGEMDGLQIVFGNKENKKTLD
DLYENWPLVRSGTIALGEFLEKAMAYPNKPGVFRILEVGAGTGGTTKYIVRHLQNLGVPF
EYVFTDLSSSLVAAAKRTFKDCPEMQFTTLDIEQEPQASWIGSFHFIISTNCVHATRNLT
TSLTSLRKMLRDDGVLGLVEITQNMFWLDIAVGLFEGWWLFEDGREHAVTPEWLWKDHMN
RAGFSAVDWTDGEEPEARTIRVIAGFPTTLSA
>G3J046|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Methylobacter tundripaludum (strain ATCC BAA-1195 / DSM 17260 / SV96)|TrEMBL
MAQEHPDELTPLQKAYAAIQQLRGKVERLEQAGSEAIAIIGMGCRTPGANDPESFWELVR
NGRDAIREIPPERWDAAAYYDPEPGRPGKAYTRYGGFVEQADRFDAAFFGISAREAESMD
PQQRLLLEVAWEALEHAGLPASNLAGSPTGVFVGVTASDYGLLQAERADQGEVNPYFNTG
TPLNACAGRLSYVLGLQGPCMAVDTACSSSLSAIHLACTALRAKDCDLALSGGVNLTLSP
LLNVTLSAAGMMSADGRCKTFDDSANGYVRGEGCGIVVLKRYADAVAAGDQILALIRGSG
VNQDGASSGFTVPNGVAQQKLIRQTLAKARIAPHEIDYIEAHGTGTSLGDPIEAQALGTV
LGQAQGRERPLLVGSVKSNIGHLESAAGIIGLIKLVQALRHGELPPTLHIKQPNSRIAWD
ELNIRPITELTPWPRGEKRRLAGLSAFGASGSNAHLIIEEAPAAEALYPERDRPVHVLAL
SAKTEPALKALAESYQRFFAQTPPSLADACFSANTGRNHFKQRIAVCAEDLTQMQERLAA
FGANQPIPGLFLGATPPAKPLRPVFLFSGQGSVYPGMGHELYALHPGFRQAMDNCAAILE
PLLEKPLLSVLYAEEHRSDGEALLKQASYAQPALFALQYALACLWRSFGLEPAAVLGHSI
GEYAAACVAGVFSLEDGLKLVAERGRLMQTLNENGAMAAIFADEALVEKALASHRHELSI
AAINGPQHIVVSGRSSALSQVLDQFREAGIESYPLQVSHAFHSPLMEPILEDFERFARQI
RFHAPELPFISGLTGLALGKGEVPDAGYWRQHCRQPIRFAEGLAGLIPHPSPLPQGEGDK
VAAAFGRNFELFLEIGPGQVLANLGKRLAPSAAWLPSLLQPKPDWSVVSTSLAEAYARGA
DIDWSGFDAAFGRNRVCVPTYAFQRKSYWLAPKESIMTNPQQATSQPVQDDRARREAILA
RLCRLFSGLLRTEPSEIDTHAQFLEMGADSLVLVEGVRIVEDNFGIKLEIRQFFEEITTI
DAIAGYLADRTTADLSQETTATPVSQSVPVQAAPTPSPVDRNESVRATARTDVSGNPQPN
SPETPPRATLGGPYSGLRPPVSAIADGTALQQIVLAQTQLMAQQLALLQGMPAPADIGYG
AASAAIPAQQEAPRPLQPQALAQHADTAQPQQNSEDRSSPLRALNNPIVPSANGLNPQQS
RHLAALIERYQKKTPKSKALAQACRPGLADSRASVGFRFSTKEILYPITGAESMGSRLRD
IDGNSYVDLTMGFGVLLFGSRPEFMRGVLETEIQHGFQLGPRSEHMQEITELFTEITGHQ
RVAFTNSGTEAIMIALRLARTTTGRHKIVIFEGSYHGHSDGTLAKTIRVNGELRSEPVSP
GVPPNLAKDILVLEYGTQETLDIIREHAHELAAVLVEPVQSRRLDFQPVEFLRALRSLTE
ETGTALIFDEMISGFRAHPAGVQGLFGIKADLAAYGKIIGGGMPIGAVAGDARFLDGIDG
GMWQYGDASYPSATRTYFGGTFCQHPFSMAACLAALRHLKAEGPALQERLNQRTAALAKT
LNDYFEAEELALRICHFASTFHFKFPGNLEMFYYHLLEKGVYIWEWRACFLSTAHTEEDI
DLIVKAVKESVEELRQGGFLPERSQAAGSSDAAIPSNKKNLADSTDRSWFRHNSKLSHRE
TAFTAKATAGKRGLGFGLFYFGNYDAAFSTGKYDLLLEGARYADREGFRAVWIPERHFSE
FGGFSPNPSVLAAALARETQHVQLRAGSVVLPLHNPIRVAEEWALVDNLSNGRVGIGFAS
GWHPNDFVFAPDSYGKHRELTFEGIDTIRHLWRGESITMRGGNDSSVELNIYPRPKQAAL
PAWLTIVNNPDTYRKAGEMGLGVLTNLMGQSMEDLANNIAIYRQALAEHGHDPDAGNVTV
LIHTYLCADPEQAIREARQPMCDYLLSSIDLFQKMAQDVGPSTDLERLSPEDKAYIVGKA
YEKYVATSALIGSPESCAPIVERLIGIGVDELACFVDFGVAPDSVIANLPQISLLKEKYT
AIDSGEDAGFPLSEAQKQLWVLAQLDEDGNRSYNDPAALLLQGPLNQEALRVALEQTIAR
HESLRARLDAAGERQWVQPAQAVSLPCIDLSGEENPETALQHWLLEKTRQLFDFSQGPLF
YATLLKLEADRHVLALSAHHIIGDGPSMGTVLNEIMALYEAACRGEAAKLATPIQYRDFV
HWQQIQLDTAAMATHEAYWLQQFANPAPALDLPGDYQRPSVKTYNGARAWSEIDPDLLQS
LKNLGSKQGCTLYMVLLAVYSVLLHRLSGQDRLVIGAPYTGRGLEGSNALVGYCVHLLPI
VSEIGEAERFDEHLHHVRNTLLNAYQHQDYPFARLLDKLNLKRDNSRSPLLSTIFNLERQ
PDMHEAAGLQVQVYPQPVTYTRVDLTLTANLRDDRVVLECDYNTDLFEAATIQRLLGQYQ
TLLEAVVSQPQQSVSRLPLLSESERLMQILQWNKTETAAQPTCFHTLWESQVAKHPDRIA
LVEDGPEGRTFTYDNLNRRANRLAHYLRGMGVGPDLRVGICLDRSWQLMVALLASLKAGG
AYVPMDPSYPAARLALLQSDAQVAVLLTQQYLLDRLTELPQQVCCLDRDSDAIDRESDRN
PVNNVMPNHLAYVIYTSGSTGKPKGAMISHQGLVNYLQWAVRAYEVEQGDGAPVLGSIGF
DATVTSLFVPLLVGRRVVLLPDGEELEAMAALHRSPYQFSFIKLTPAHLEILNTLRAGDP
SADAHLTRYLVLGGEALPGAALDPWFKHTATLTVNEYGPTETVVGCCTYEADSPIAGSVP
IGRPIRGTRLYVLDSNLQAVPPGVPGELYIGGAGLARGYLDRPGQTAAGFVPDPFSHDVD
EPGARLYKTGDRARYLADGTLIFLGRIDHQIKLHGYRIELGEIEAVLADRPEVREAVVLL
REDQPGNPRLVAYVSPAQDQPLNADRLRQELKLLLPDYMVPSVIVPLTDMPLTSHGKIDR
GALPVPDQSRPDQDGHYTPPGNDIEHRIAAVWQEVLLLDKVGIRDNFFDIGGNSLLILQA
YKKLQPLLPNDCLVIELFKYPTISALAAFLSSDTAPIQPDYAGIKDRASRQKAAVGNQAR
RRRTPQVKV
>A0A139XWA6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii ARI|TrEMBL
MTEAATPQNVTSPADLSKQNVSFRPGVNAVEFVSGYSHAGSVVCSLPSPIFFNKASSSNG
NCESNASTASSSAALGTEASSNVRTGTVLIFDCGSGNTWQHLRQWLSDEGASHIVVVHAC
AEEGADTLGVKTLHPSRVNGGQGCSQTLIKEVKCRPHHPEEVVELFKLLKEGLHFPLVRG
IFYILGEKLDSLLANQTTSSVHDMMKTASGAWSIHHALGQLGMEADLDFFIFFSSISALF
GSISQSISAAVHASLDALAYYRRHLGLAATSIQWAPWADGSSATSPQIVRHWLEKGGVSS
VRNPLAAVSAILKNHTAIGAVVACFHADPTIMHEMGETDQECTFLSSGPAANTRDSTSGN
VKVRTNPVKSRVFQNVSPSTDTCGENHKDELLVILTQLVRREVIEIASCYVFFEGNNLST
DESLVDLGLDSLSAVELRHTLQQRFCVNIEPTFLQANATIDSISALLVTHVATSLTGALP
VLPLSCPGLASAVDDCALVSLALRLPGRCDSLDAFWASLQSDSGYCRPGASEACDQCFMH
RAGSGELPAESQSIGTNLDARKGFCWLSNRDAFDSHFFGISFTEALATDPCHRLLLEATY
EALCKLNTEQQSGTSGTPIAVFATSSSTQMRASLPSYTKPASSQNTQDNNGCLAASFLSY
HLNLTGLAVPIDGSDSASLIALDLGREHLRGTDSVCQAVVVAAGSLLPICSHGWPSACTS
PTIRRFRGRDDYAFPDRETYAVPRGEGIVSVVLQRLSVARENGNSPMAILKGISLIRMGR
GERPIPSQWRTADVKLRRKTIVEALKMSRVEPRTVAVLETDGLTGSQAEDAYTVEAMADI
FGPRHLAESCSPLVIGNASLHIGQAREASGLATLAKLVLMLERGYAPPIPRLRRLHPDVK
RGILPSGFVMFPCKKMDLLAFRQHPDHVYGPNEKRDQKEGRPLIGCVSSLGSDKTSGCFI
VESSPRRHGRTSDTRVSLERAVPLAGTKDACSHNYLHVRSTDGSESEIRGDDRAVWLFCD
DLWGLQSVGRGLYCSDPAFAALLEQAERVLGNRIPQPLSCLLYPSTTAEFQKAEDALAFP
RIAAFVLFSLQWALATCLRHQEGEPTAVMGLGVGEIAAAAVAGILSLEDAVELLELLSSE
TRTCDNRNKPMPGGNVNSGGLFDRGNSGTGGCGVAQDCKSPWVLCGLNKTPTSESAALEF
SVLESRRGSSSRKSSETPTSNTTPHNRDVFQERFSRKPRRATCPSPIIRHAWEKVAHGNP
ENDEEAELECPSSQSRRANCPSPAIQHACEETAHGNHANDGEADLLMDLFRFRPEPSEPL
GQVTARIALRNATCLFISTVSGRLATDTLIRAAEYWDPLVPKTQRVHRAVETAVQVAKTA
KLVCIGCSAQDGVHLSVGLPSVHPISPSPLRIFCFTGSSPSPQLLAPCESASGSSPRVAV
VEHHGADSNLGGGAPWWKHLLFRLPQLEGFPSGCSASTRLLADRLVADVPTPDNHMINNP
QTAAVQGAGETLGTLREGSSGEGEDGEKGYRSESVNTQHPVYKVYRRCSEPELHESELSL
LCSDTVCQPSLEKTVELFIGTGLEQQGKLSTVSSSWLVFSDIVAPSPISLYSTLAFQNED
GEQRFCTLNVASQVATVYAEKVKTQVCSIIIECKRGFKPPREIARCHFVKNQTAVGKHEP
AVSSLSRIRWLPATKLPEGWLRTRRPHVWPCKIKVTKAACPLPTRRVDLQEIYWGKRHIL
CRFRMPRNPPRDGVEKSTQLIAILARLVTVSVGVAATCVLHETETSGRYSHSHPGPQVED
DQKTHMDALWVCPYVPFSECWCVIRHRRNGSSIKEGKGRDWETCDVEIFSENGTAVAVVL
GFGIQSHALSMRMMGGRGNDGDSSVSTTVCVA
>A0A378JJZ3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Legionella busanensis|TrEMBL
MRNKQELILDKISQFSQSTPHKIALKFFESDYQNNQELTYQQLNERIHLLANTLVSLNDN
QSFTQKPILLIFDSSIHYIASFLSVLRSGNIAVTAYPPRHLRHLNRLLKIIADSKASIIL
TTSTIKNYCDLQNFQFSKETLFICVDQLNDELRANSENLPIIKPDHIAFLQYTSGSTGMP
KGVVVTQKNISANLSLMKRVLGEAGVEKCISWLPIFHDMGLIGNTLLPLYSGGTCVFMAP
LTFLKNPFFWLKIISSEQGTYTMAPNFAYDLAINAFKNQDPSQLELNFSNVHCLINGAEP
INPETIREFEKNLKPYQLKDGVIKPGYGMAETTLYISCEMSDKRFFMVNNNGLDKGIINR
DFKEKFDLQVELVSCGKLDPDYLVKIVDPKTLYTLPVDTIGEIWIQGDSVASGYYQNPEK
TKEIFQAFTEDTAEGPFLRTGDLGFIDKNGYITVCGRLKDLIIINGRNIYPQDVEYACFR
SDSALVPNCAAAFSFTINGSEECVLVAGVKGNLEETIYQAMMRKVQKEVFEQTDLVLYDI
LFVPSREVLKTSSGKIQRSACKEAYITNQFKVLARLKDSQPPNFKDNIIEQTLDTNIISW
LKEWIARQAKLPIEQVAIDRAFAEYGLTSIQLVTMINDLEKVIGQPLDPWFAWEFPTIEA
LHQKLTTHNTDKTNKLVGNYEPIAIIGMDCRLPGPDGQDINGINAFWSYLQADNDSIRAI
PNDRWDNRLYYDQEITKKGRMYTTGGSFLTNVKQFDTKFFNISPREAEYLDPQQRLTLMT
TWHALEDAGIIEDDIKNSQTGVYLGISTHDYDQLIQKQVPLDELSTYQATGTSFATAAGR
IAYFLGTQGPCMAIDTACSSSLVSVHQACRALQDGDCQLAIAGGVNLILSPEGNIIFCKS
SMLSPKNRCSTFDIEADGYVRGEGCCMIVLKKLKDALQDGNKIHAVIYGSAVNQDGASNG
LTAPNLIAQVDVMEKALSLANLRPEQITHLEAHGTGTALGDPIEWEGIRRSYGLERQNPL
YITSLKTRIGHLEAAAGIAGLIKTALAVKNSQIPAHLNLKEFNPKLHQQDNMIVPTSLIV
WEEENRYAGVSSFGFSGTNAHLILGMPIHSQKSEFKEKTTIRTEHLWVISAKERAVLLQY
LQDYCRYAEQKPSLHFPSLCNQSLTQRTHFAHRAFIIAPDQESWLQALRHNRWQEGVISE
NNQLAWLFTGQGSLMPNIATELYRTIPEFAAIIEKCCAIAQPLLPYDLRAVLLDTPKSID
INYTLYAQPTLFIYEYALAQWFLLLGLKPNILLGHSLGEYVAACIANIITLEDALYLVCN
RALLISSLNNNGAMLAINAPLEVVESLITNFDSLVISLKNGPEQIVVSGQDNAIIDCQNY
CQHHSIHCKNIATSHAFHSPLMQPIIEQFAKLAAEITYKSAQIPVVSNITGQILKDGQMN
AEYWCKHLLQTVEFHQGLHTLVDNGIELCQEIGPKPILITQAQNVHNFITLPSVSAPDNP
WPGIMETLGRLYLRGVKINWPILNKHINTKVEDLLNYPFKGKEYWLPDIKIASAEDKWKS
YLYHQLWQKISLEPNLINLNDKNIALITNKARKHISHLIACQKLTFITLGSVQNSTLSET
LAGQEVKEADWLVYFCQAEQTDLLEETTFLNQMIQQLIQQWPSKPLLFLCDSNSLVGTSL
LALLKSVKQEYPQWPIHYLETILLDRETQLQFIGASNPNYWALRYHNGDYYEQQIKPLEP
EQLGDSWKISLQTSCLVTGACGDIGQAFIESLTQMGARYIIAVGRKEKESKWSDIIMMQK
SQGTQIRYYACDISNSTAVEHLIQNLPADYPPLGIIIHAAGVNHNKPLLKTTDEDIAEIL
GAKALGAWNLHKATTHCDLKVFNCISSLSAVLGNEGQAIYATANAFLNALSEYRHEQNLP
SQTFILGPVKNTGLFKKNEEKLTSYLKVKGVEPLLRTEIQAVFQSQIKEYNLIISHFLQL
PNQPPKEEPIYEGNISHNKEVSLTETILTIAEETLRLAPGELSIHDNWFKSGMDSIMASQ
LAYKINHKYPEAQTSAKDIFNYASVQELAINIKEHISENNVDRLDDKHVYQQMNTLPLSL
QQQEIWNFIKNSPTNLAYQIPIELSIIGPLSVERLQKALSEVVKRHDILRCSFHEVLNQA
KQHIHKECSLKLEFGEHDSEKEIADFLSALFVLQKPPLIRTRIIRQEKDKYRWLLVFHHL
LGDSYTVTSFINEAIAIYEGEILDQEPVKYCDYVSWQWNKIHYNLVNEMGEFWRQRLQEV
PVGVALAKETHQPKEACIINHQLSLTDISRSIKALEKNKLSLSNYLLANLFEILLDYFKQ
DQQGIVVFFSGRESGEFSTVFGDTSNDVLIVAEREQNILTQTQKLQEQILSMHDNQYFRM
PIFKEIGLSTPMISFDFQRSPNYSVKSSLEINIVKNSNVQNYLWGDEPRLLSFKVLVKEG
NLRLSLKYRHDKIESKLAQGVLEAWANNLLKQEASDLQIATKTMPRLYTASALQQNLWQL
LQNHPDGIPYYVLLFKEINTNIDIKHLNKALQQTIDNNPALQVYFVEEKNQLKWDINSAA
TTVIQTITADDLNTKMGELLLEPIAINQAPLLKIYLIHHANGKKPILLFRFHHLIVDGIS
AELFAKEFEKNYMNKSEVFVSKEQQIFYLNEHLKEEKFYSQNIADYKTYLAEINQRLKDY
HCNKLTENNYLGGVIYQKISKENSAKVIDFCKNHSISPYAFYLHIFGTVLASLSSEREIY
ISIVKSNRGKLSQTGMIGYFADNLPIILEINPDTINIIQQIKSTQMQILEVIERFSYPIL
SKDLEKFDYKQPPFIFNQYTLNESENETEALLSSADYLIEGLLKASQNQVSLWNYQNPEK
FNLLIRSSVHGDMLGLLYNQQLASAADAGLVLDEFINKLICLLE
>A0A0N0MMT3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OV450|TrEMBL
MEASVEQLVTALRQSMLDNERLKRENSELAEGADRASEPIAIVGMACRYPGGVNSPDDLW
RLVAEGRDGVSAFPEDRGWNTDALYDPEPGKPGRTITREGGFLYDAGDFDAALFGISPRE
ALALDPQQRLLLETSWEAIENAGIAPHTLRGTKTGVFGGVMYHDYALGTEAAATTGGSLV
TGRVAFSLGLEGPAVTVDTACSSSLVALHLAAQSLNSGESTLALAGGVTVMTEPDMFLYF
SHQRGMAADGRCKPFASAADGTGCSEGVGVLVLERLSGARRNGHRVLAVIKGSAVNQDGA
SSSMTAPNGPSQQRVIRSA
>B2J540|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MNSFSKRISEMSPVKLAFAAQQLESKLELLKAEPIAIVGLGCRFPGGVDSPEAYWELLRN
GVDAITEVPKERWDVDAYYDPDPSKPGKINTRNGGFLAEVDGFDPHFFNISPREAISLDP
QQRLLLEVTWEAMENANQTPQNLFNSPTGVFIGISADDYSQRLLDAEGREGIDAYFGTGK
AFSAAAGRLSYFLGLTGPSFAVETACSSSLVSVHLACQSLRQRECNLALAGGVNLILSPE
ASLTFSKARMLADDGHCKTFDAAANGYARGEGCGIIVLKRLSDAITDQDRILAVIRGSAV
NQDGPSGGLTVPNGPSQEAVIQRALATAGVEPAQVSYVEAHGTGTFLGDPIEVGALGAVF
GKNHSPSNPLNIGSVKTNFGHLEAAAGIAGLIKVVLQLQHQEIAPHLHFQQPNPHINWEA
LPITVPTQSTPWIVPGDRRIAGVSAFSFSGTNAHVVLEESPTSGTSSVTNPEQPFNLLTL
SAKTPEVMQKLASRYHLYFKAHPELSLADVCFSANTGRSHFPYRFSLVANSSSQLCDQLA
ALAAGETNVTGIWQGQQPATKSKIAFLFAGQGSQQAGMGQELYATQPTFKAALDECAEIL
RPYLDVPLLELLWGNSSHLLDQTAYTQPALFAVEYALYQLWQSWGIQPDAVLGHSVGEYI
AACVAGVFSLADGLKLIASRAKLMQALPSGGAMAAVLVDKSKLVQALAPYAKQVAIAAHN
GPRSFTISGAVEPLEAVCKALSANGGKIKRLSVSHAFHSTLMEPMLAEFEAVARQVKYQQ
PRIPVIANLTGQVAGGQIATPQYWVRHVREAVQFEMSIQTLHQDGYELFVELSAKPTLLS
MARQCLPESTGVWLPSLRPGQSDWQSLLSSLGQLYVSGATVEWSSNRPSHKVALPTYPWE
RQRYWIETPQKQAQLARSQSTASTSIVRLIDQGNTQELLQQLATTSNYSPEQQELLLEML
TQLVKQHHQQVTAESIQDWLYELNWRSQARFGKELYPNYLPTPEQISSDLNPQIAELLPE
LNSYRQEVLSPLEAISIDYVVKAFQDLGWNFQIGSRFSTESLAQQLGVISQHRRLWQRLV
EMLAEVGIVQRLGTQWEVTQVPQKGDPQAQIEHLHHQYPAAQAELTLLGNCGPNLAEILQ
GKCDPLQLIFPDGDATIATQFYQESPGARVMNILVRQAVSSALQQLPVGRGLRVLEIGAG
TGGTTAHLLPLLSQEQTEYVFTDVSPVFLGQAQQKFPDYPCLRYQTLDIEKDPISQGFPA
EQYDIIVASNVLHATKDLRVTMQHARQLLAPGGILVLMEVTARQRWLDLIFGLLDGWWRF
EDVDLRPDYALLTTVQWQKLLKEVGFSTTTALPSITQNSGVLPEQAVMVAQVAKIPAYSS
QNWLILADQQGIGQQLANQLRSQGQECVLVFQGEKYRDLGEQSFVVAPDRLEDFSRLLTS
QSAINKVVHLWGLDAPNADVLTVEGIKTATHNGCGSILHLIQAILQAEASQLPRLWLVTE
GTQAIANQVLPLPGIAQSPLWGMGKVISLEHPEAWGGMIDLEPGLASEKAASILQAEILE
SDGEDHIVFRQQQRYVARLVRSQHPENLQNLKFQADGSYLITGGLGFLGLKLAQWMVEQG
AKEIILAGRRGLPPRQQWASLSENTEEGRKVKAIQALEAKGAKVTILVVDVCDLVQMSLA
LKQVHTIHSPLRGIIHAAGVTPGYQALQNLDSKTLEAVLYPKTVGTWVLHCLTQEIKLDF
FVCFSSAGSVWGAKGQGDYDAANHFLDTFAHYRRSIGLPALSVNWALIGSGGMVNAEYDR
WLSRIGIEEFPAEAGFNALGFLLAANVTQTVVAKVDWGKFKAVYEANKQRRLLLDIEVAS
ENEPEEATVKQPEILEKLKTAQECDRHDLLVAYLQSEVAQVLGLGSAHLPDPQQGFFNMG
MDSLITLELRNRLAASLNCTLPSTLAFEFPTINDLVAYLSTEVLGWESSVTETLELPITH
EQVNTLFEIEQLGEDEIEASISQRLARLESFLQDAN
>A0A0P1IVP6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Cognatishimia activa|TrEMBL
MTKQIFITGQACRLPGAGSAIEFKDLLQDGRCAVSSIPLNRWQHDLFYHPTPGTKGKSYT
FAAGVLNDIWGFDLSVFNISPREANQMDPQQRILLQVVWEALEDAHLKPQDLAGQEVGVF
VGASSMDHATILGKDAALADSYLMTGNTLSLVSNRISHAFDLRGPSFTVDTACSSAMVAL
DQARQALEEGRVDTAIVAGVNILLNPGSFVGFSAARMLSETGLCQSFSANADGYVRGEGC
VAIVLQRDSKAPARARAKFIGSDTNADGFTMNVALPSEEGQRALLTGLYESLEVSPNDLS
FIEAHGTGTLVGDPIEARALGRALAVHRDAPLPIGSAKSNVGHLEPASGLVGVLKTLIAF
EDKRLPPSLHADELNPHINFEEENLILAREGVEFEASEKLTAGVSSFGFGGVNGHCVLET
VTLEPAAPAIAPNAPERIFVTSSFCEASLREQAEIFAEDMAPADLEPGGLPDQLWHGRGF
YPKRLGVLAGSASTASEALSAFARGEKDPRVVTAESKVRNEPTVFAYSGNGAQYAGMSLQ
AFRKDAAFREMYLKIDQEFQSHTGWSLVEKLEGGLVAEDFDDCLVAQSLLFADQAAQTHA
LASRGIKPAAVVGHSAGEVAAAWACGALDLAQAVSLVVSRSKPQSRLVNKGTMAAFQTDA
DNALSLLDAYHAENADYEWPVEIAAINSPVSVTLVGPKDQLTAFSKWVKRAHRLACIILP
INYPYHSAQLEPYEQELHEALDGLQVKSTDIPFFSSTEGCLVKWDLLTIDYWWRNIRQPV
QFGAAVDAALVAGFKSVLEVGAQPVLANYITATAQKNAVADVSVGHTLAKSDPENVNPMS
RAALFAVLKGCAHEEGAFFSEAAPSTAQLPHYPWQNTEIKSVDSEAITEGLGTDADYHPL
LGRPTGTGATVWRRDTDDQIFPALKDHQVGDASIMPGMALAEMAYAAAAKVAEGKPVEIR
NLDLVGPVVLSGTAGVDIKTKVTPETGAIAVQSRARLSQDMFRDNLRASYSILSEPATIL
GQTAPSLISEEEDRGRWTYANARRIGLNYGPKFQGLQRLRINGDVFEVSLKEGVGLGASG
QLQGFDPVQADCLLHALIAGFVNSTFDLAGLALLPVRIERLQVLQKAAPLATGRLIVRRR
GNQSILVDVFGFDPDGQPALFMKGLRLQAVSLVPQIDFDDHAYHFAAVPCLPVTDIPSVD
ASHAQRAFESAMTAANAEDDTLLLLNAATHQALWSGFDSAVKADRKYEPREAFEKAETLW
LEMLGSMGLAHKDAENGGWLIAEACDLPDAATIGLALLDEKPDLVSELSALLRLPGAVHE
YLSEAAPEKDAASQLFGHHVANTLTTVPQPALSLVTALTKEVLRTYPESARLRVAAAGNG
LKVFADLSDAYDGLKTFELLSEAEEAAGLEGVYKIKADEAQALECVVLADPGRLMEDASA
AHLTSCLRPGGHLIVQCSAVPALNAAISALSPDGTTQEVAPDQLRRTLDRLGFETITQLD
IPDGYGQGELFLCAKRVSILSDDTKTEDTQLPSSWEDIWFARYGQVVRKSGVLDTVTPAD
EKAPVLVLCNRNEEDRAISDRLLCLRDIAVQCVEAKRGLVAVVPNGAQYGEGSAAQPAQH
ALWAMLRTIGNEFAQIRIQAIDIAQVEPLEWSEQSEIIVNTLDALPDESEIVLTPNGPLA
LRVRQGLPQLEDGQNISALPEGASLERSVSGGLAKLEWTSKTRRDLEPTEVEIEVAATGL
NYRDVMWAMGLLPEEALETGFAGPTLGLECSGHVSRVGSQVADVSVGDAVLAFGPACFSS
HLISDQSWVTKLPEDLPVDDAAALPVAYFTAHYALETLGQLQPEDTVLIHGGAGGVGLAA
IAVAQKIGATVIATAGSPVKQQFLRELGVEHVLSSRDTTFVREIRRLTDSRGVDVVLNSL
AGQAMSDSLELLRPYGRFLELGKQDYYANTHVGLRALKNNISYFGIDVDSFLADRPDMAR
RVFKDVMDAMSSGEYPPLPYTKFGADQTVEAFRLMQRSGHIGKIVVAPQSQVSDTNPLSG
ADAFSADPEGWHVVAGGLGGLGLEVADWLYTRGARRIALLSRSGKTTPELEPRFDLLRKS
GVELEILACDITAQTQVQQTFDRLRQKAPLATVFHSAMVLEDQPLAQISAESLDRTLPVK
TVGLENLDIETRKDDLQAFIAFTSLATMIGNHGQAAYVAANAYQEALIKNRHALGLPALA
VGWGAITDAGYVTRDENLGRMLAQMSGNVPFTTAAALNALGRLSMSSVPGACLTITPMKW
GPSLAALKILHRPSHERLKQLAESSGKGRDAGDLRAELQSLPFAKAMKKAVAFLRAEVAG
ILRVPDSKLSASRPLSEYGMDSLMGVEMGLAAQEALGDDLPVPVLADDVSIENIAEMFVK
HIQSGGSDDSEDGQDSESRKITQNWERQHMNTPNPATTQ
>B2IXJ8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MSSEKTGLEVAIIGLAGRFPGAKNIEEFWRNLQDGVESVKFFSDEELLAAGIEPALLSQS
NYVKAGAILNDIEMFDAAFFGYTPREAEILNPQHRLFLECADEALENAAYNPQTYKSPIG
VYAAVGKNDYLLDNIYPNSDLIEAVGVSPILIANGDYLSTLVSYKLDLSGASITVQTACS
SSLVAVHLACQGLLSGDCEMALAGGVSIRLPQMSGYIYQEGGIVSVDGHCRTFDAKAKGA
VGGNGLGIVVLKRLENAIKDGDRIYAVIKGSAINNDGAQKIGYTAPGVEGQANVILAAQA
TSEIAAETITYIEAHGTATPLGDPIELEALTQAFRTSTAKKGFCAIGSLKTNMGHLDAAA
GVAGLIKTTLALQHKVIPASLNFEQPNSKIDFANSPFYVNTKLSKWDSVNTPRRSGVSSF
GIGGTNAHLILEESPLLEQEDRGAEEQGRKYHLLIVSAKTDSALETMTVNLAEYLQQHPD
INLADVVHTLQVGRRTYNHRRMLVCRNLESAIIGLKASEPSQYLTTFQEKTQRPVTFLFP
GQGSQYVNMARELYEVEPTFQTEFDHCAQLLLINFGLDLHRLLYPEASVQETAQAQLQQT
HLTQPALFVIEYALAKLWMSWGIKPQAMIGHSIGEYVAACLAGVFSLEDGLTLVITRAKL
MQELPKGAMLAVPLPESEIKPLLNEQLSLAAINAPSQCVVSGLADAIATLQNQLTKKGVD
CRLLHTSHAFHSTMMEPICAALTEQIAEIQLHSPQIPYISNVTGTWITPSVATDPNYWTK
HLRQPVLFNQGVEELLQESDRVFLEVGPGRTLSTFIQQHSDKNTGITALASLRHPRDESS
DVAFLQNTLGQLWLAGVEVDWSGLYIHERRQRLALPTYPFERQRYWLDAPNSAEIPSSPQ
LLPNKKLDISKWLYIPSWKRTVSPSRRHSSPGCTLVFSDDCGLGLGIVRQLELEGETVIT
LKVGSEFHQISERLYSLNPKNHQDYDTLLQELHRQGLQPQKIIHLWSVTENYTPELEIAE
FDKAQETGFYSLLFLAQTLAKHHVIDELQITVVSNNVQQVTGVDIVCPAKATILGPVKVI
PQEYPNITCRNIDIIIPKSSQDKLVEQIVAELTCDNLDKVIAYRGYHRLVQTFEPVQWDE
SVVGTPRLREKGVYLITGGLGKISLLLAEHLAKTVQGNLILIGRSPFPAKDSWEQWLVNH
DHTDSISQKIQKLIEIESFGGKVLIINADVSNQQQMQAAIDLAKEKYGRVNGVIHAVAIA
DSFHAIEQTSYQECLQQFQPKIHGLLVLEKIFQNQKLDFCLLLSSLSSILGGLGFVAYSA
ANNFLDIFAHKYNPNNSIPWISINWDAWQFDSEPKITGNLAELALNPQEGIKIFQYIFSQ
PDVNQWVVSTGNLQARIDQWIQLKILGNRKDLKSASSITHHARPNLRNAYIAPSNEIEKC
LVNIWQDLLGIEPIGIEDNFFELGGNSLTAIQIISRLREIYLIDLPVNDFFETPKIISLT
ETIFQAQIANADSEILAQALADLAKLSDEDVQKLLAAE
>F1TIX3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
RGIGSGQVQMAVMEGNAAQMKQKLLIAVPAAARPQKTPAGSDSTTEINTGSLLIKLQSDV
ELTVSILLKVKVQDIDADAELSEYGFDNVKLAELAHEINRKYSLELTPAVLFEQRTIHSL
AEYLIAEYKNVFVKRFEQEAFETTNKIHQIDPGLLREKTLHQFKALFGEVIKLSVAKIDP
DESMENYGIDSIVITQLNYKLADIFGGLSKTLFYEYQTMGALVEYLVTDYPQKCMRWTGI
EDEVQLIPEVSSTTLPVKGVFRKLASFKAEKKQERSFTVMAPANRVMEPIAIIGLSGRYP
QAKNIQEYWRNLESGKDCITEIPEERWPLEGFYYPNSKGAIPQGKSYSKWGGFIEGFADF
DPLFFNISPREAINMDPQERLFIESCWGVLEDAGYTKEQLATKYNQRIGVFAGITRTGFD
LYGPDLWKQGENIFPYTSFSSVANRVSYLLNLQGPSMPIDTMCSSSLVAIHEACEHIHNG
ECEMAIAGGVNLYLHPASYIGLCAQNMLSADGKCKSFGRGGNGFVPGEGVGCVLLKRLSQ
AVADEDHIYAIIRGTSINHGGKTNGYTVPNPTAQGELIRTALEKAGVDARTISYIEAHGT
GTELGDPIEISGLTRAYRKDTQDTGFCAIGSVKANIGHLEAAAGIAGIAKILLQMKHQKI
APSLHSSELNPNIDFAGTPFIVQQELAEWKRPQIKIDGETSEYPRIAGISAFGAGGSNAH
AVIEEYIPKLKRPQIQVARGNPAIVVLSARNADRLHEQVERLLNAIQVQGFSDNDLADIA
YTLQVGREGMEERLAVIAGSIKELEEKLKSFLEGQDDIPDLYRGQVKHNKDTLAVFTADE
DMQKAIEAWVVKGKHAKLVNLWVKGLIFDWNKLYGDTKPCRISLPTYPFARERYWMPD
>A0A2S9YVF9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Enhygromyxa salina|TrEMBL
MTEADDQKKLRSYLERATAALKQTKRRLDEVESRQREPIAIIGMGCRYPGGVGSPAQLWE
LVASGHDAISELPVDRGWDTGALYDPDPDNPGTSVSKHGGFLHDAALFDPSFFEISPREA
PAISPQQRMLLEVSWETLEHARILPSSLHGSQTGVFVGLMYYDYGAHLVTNPAALSGYTW
IGSSGSVSSGRISYTLGLQGPSITVDTACSSSLVAVHLACQSLRAGECSIALAGGATVMA
TPTIFVEFSRQRGLALDGRCKAFSASADGVGWGEGVGMLALERLSDAQANGHPILAVIPG
SAINQDGRSQGLTAPNGPSQQRVIKAALESAALAPNDIDVIEAHGTGTRLGDPIEAHALL
AAYGRERDPDQPLWLGSIKSNIGHTQAAAGAAGIIKMALAMQHEQLPRTLHADAPSPEVD
WSDDKIRLLQAPVAWARGDRQRRAAVSSFGISGTNSHVIVQEGPATATPPDRETPNDAHT
PLLVSAKSLASLRLQAGRLRDHLLAHPDLALTDVAFSLITTRTQFNHRAVVVGRDRAGAI
EALQALADGRPDPRYIEGVAAVEGKLVFVFPGQGSQWPQMARALLAESAPFRAQIEACAA
ALDPHTQWSLLAVLRGDDAAPPLQRVDVIQPVLFAMMVSLARLWESLGVVPDAVIGHSQG
EIAAAHIAGALTLQQAAKLVARRSRVLLDIAGTGAMAVVAMGPDAVRERLAAYDGRLDLA
VDNGPNATVVAGDADSVTAFVEAAWAEGVFARQVDVDYASHSAHVDPLGPELALALEGVV
ASACTIPMMSTVTATWVDGAQLDHDYWHRNLRNTVSFARGVEQLLESDHRFFIEIAPHPV
LSVALASLVDDHAAVIPSLRRDDGGLDRMLLSLGSLYARGVAYDWTRLLRDRAPRTVDLP
TYAFDHQHFWIDGPLTAAVARPSPSSALDSSFWSAVEQRDAASLGQLLALDDGGVAALDA
LLPSLQTWRRDGERQAALSSWRYEVVWRESRAPRAGLAAGTWIVLAPASDDPIPSALVRA
LTQASGSAELIVVDPGATQAQLVSQLRDRSPSPGPNPGPNQGFAGVVSLLGLDESPYSNA
PAIPTGTAHTLALVQALIAESIDAPLWLVTRAAVAAANQAVLAPTQAMVWGLGRVIALER
PGAWGGLIDLPDAGEADAQARALVGMFARGDGEDQLALRGGRVYVPRLVHAPAAPAASFV
ARGTALVTGGTGAIGSHTARWLAREGVEHLVLTSRRGMDAPGVEQLCAELGELGPKVSVV
ACDTADRGAIERLLAQLQANEAPLRSVFHAAGVAGELTALADVTLEEFTAVLAGKASGFR
DLHELTRDLELDAFVAYSSVSSVWGSGQQAAYATANAYLDALTLHRSHLGLPATSVAWGA
WADAGMATGSMGEHLERRGLRPMDPQLAISGLSQVIGGQPATVMIADMIWERFAPTFMSS
RHRPLLDELTEVQATLTPAAEPSERERDELLEQLRALPDSARARQVLSLVLSTAAGVLGF
SDGSSLDPRTGFSDLGLDSLMAVELRERLKQATGIPLPSTLAFDYPTPERVTELLLSELA
EAIAGPTAAARDHADDDELWSVISQIPRESLRESGLYEQLVALANAQQPAPAPTAEDDFD
ALDDADLLSAALDLLDV
>A0A2X4U1T1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Rhodococcus coprophilus|TrEMBL
MADMEMTVAELRDWLRNWIADTTGQPVSQITDDRPLEEFGLSSRDAVALSGEIEELLDVT
LNATIAYQHPTIASLATRIIEGEPERPEDVDDAASYAVRPTGMSKDIAIVGLSTRFPGNI
RTPDEMWDLLSSGRDAICDLPEGRWSEFEGDPAVRDSIRKANTRGGYLDDVKGFDAEFFA
MSPREVEMVDPQQRLALELTWEALEHAHIPPSDLKGGSVGVFIGSSASDYMLLASVDPSV
AHPYALTGTSTAVIANRVSYFYDFHGPSVTLDTACSSSLVAVHQAVRALRGGEADVALAG
GVNMLLAPAGTLGFDELGVMAPDGRIKAFSADADGMIRAEGGGLVVLKRLEDAERDGDDI
LAVIAGTAVNQDGRSNGLAAPNPEAQVDVLRRAYRDAQILPSGVDYIEAHGTGTVLGDPI
EADALGRVVGRGRDADKPVLLGSAKTNFGHLESAAGAAGLIKVVLAMQENELPPTLNYTA
PNPYIPFDKAHLQVIPEGAKWPRYSGRAVAGISGFGFGGTNAHVVVREYTGPQGQEAAEA
EVEIVPDAVPEAAEVPSEPARELPVVLAVSAPMPSRRRRAAADLADWLETEKGSTTPLAD
VARTLARRNHGRSRAVVVAADRAEAIAGLRAVAAGKPAQGVFTADAPASAGPVWVLSGFG
AQHRKMAKQLYLENPVFARAVDEVDELIVDESGYSMTEKFLDDSQDYDVETAQVGIFTIQ
IGLAAVLRHHGAEPAAIVGHSMGEAAGAYISGGLSLEDAVRVICARSRLMGEAEGQLEGD
DIRLMALVEYSADEITAVLSDFPHLEVCVYAAPTHTVIGGPQDEVNTIVARAEAEEKFAR
VLQTKGASHTSQVDPILGELAAELAGIEPHKLKVAVYSSVDQETLYRPGHEGIHGVDYWT
KGMRHSVYFTQAVRQALSDGHTTFVELNANPATLMSVASTAFDAGVQDGQFIQTLKRKED
ESLGVLLALAQLYVHGHSVDLGSLLPAGGYADIPRTAFLRKPYWVEARIGSAGNSRVPGA
HVALPDGRHVWEVQASAVTDPAALVVAAASQVLADVTLTASMPHAPVPAAGTVTTTLTCH
PGGASLQVHALGDDGFTLVHEGVVTSGEVLSAPVAAPVAAARPDEDSAEIADTAGDKWDP
AGSQTLEDRLALIVAESMGYAPEDLPVEIPLIELGLDSLMAVRIKNRVEYEFDIPQLQIS
AVKDASLRDVAKYLRYAVENREEVAALAEQQAADKAAERAAEAAEDAATEDAAADSEPAQ
PSVEDTTVLAEAEQILADAATAEPETAPTAAADTATVETTDDGGVDVPPRDAAERLTFAS
WAVVTGRSAKSIFNTLPVLDDEKAEKLAARLTERSGGAITVEDVRGAATIEKLADVVRGY
LESSDRIDGLVRALRPRPEGSAAVPVFVFHPAGGSTVAYEPLLKRLPADTPMYGFERTEG
PIEERAKVYLPLIEEIQGDGPYVLYGWSLGGVLAYAVARLLRERGKDVRVVGLIDTVMAG
EKVENTPDEIRKRWQRYARFAKKTYGIDAPLPFDLLAEAESDEEQIGILMGLLEMSGVEI
PGGIIEHQRTSWLDNRAIQTAELDTYDGDVVLYMADRYHDDAIDLEPAFGTRQPDGGWGD
VVANLEIVSVGGDHLQIVDEPYIAKVGADLTRKLAAIEASRS
>A1S4L6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Shewanella amazonensis (strain ATCC BAA-1098 / SB2B)|TrEMBL
MSESKTQDAQDLRLNKRLKDTPIAIVGMASLFANSRYLNDFWDLICDKIDAITEVPADRW
QIDDYFDADKRSPDKSYCKRGGFIPQVDFNPMEFGLPPNILELTDSAQLLSLIVAKEVLE
DAGVSENSAHDRDKIGITLGIGGGQKISQSLNARLQYPVLKKVFRESGISDADSEMLIRK
FQDQYIHWEENSFPGSLGNVIAGRIANRFDLGGMNCVVDAACAGSLAAIRMALTELTEGR
ADMMLTGGACTDNSAYMYMSFSKTPAFTVDEQIKPFDADSKGMMIGEGIGMVALKRLEDA
ERDGDKIYAVIKGVGASSDGKFKSIYAPRPEGQAKALRRAYDDAGFPAHTLGLMEAHGTG
TAAGDVAEFSGLSLVMGESSDETQHIALGSIKSQVGHTKSTAGTAGLIKAALALHHKVLP
PTINVNKPNPKLNIEASPFYLSTETRPWLPRPDGTPRRAAVSSFGFGGTNFHLVMEEYQR
DHGRTPYRLRSTQVPLLFAAPSREALSNDLKALCERLSNTEETFETLTAPFTLKGEPPKA
EWPRLGIVAANAKALKACLEDAIEKLATSSDDWHTQDMSFRAQAMAKNTRVAALFAGQGS
QYLGMGGELAMLYPEMRAEFIAADEVFHQRGYPGRHGTGELSSHVFPIPKFDSDARKQDE
EALTNTRIAQSAIGVVSMGQFEILKAAGLTPDAVAGHSFGELSALRAAGVIDQASYYRLA
FARGDAMASVPKGKDAGTMAAVILPDASHRSTLDTLLTQHESVVIANHNSPTQLVLAGPT
DAVKQLVQALADKGIRAIALPVSGAFHTPLVGHAHAPFAKAIDKESFSDAHAVLYANASG
DKRPTDGKSLKQSLKAQMLEQVQFESQIESLYRDGVRVFIEFGPKNTLSRLVDAILGERA
KACLILSLDAQAVGSQGRADSKLKLAAVELATAGFAITNPDPYREQLSHKAMPKSPLTVK
LSASNYLSPATAARMQASLKDGQISKQTQIVEKIVEKTQYVPKAAPAQPAPAVQTTAASE
QTSPAPTAGAGTNVGTGTLEALFAAQQQLAALHQQFLTIPAQYGEGVQALMQKQLELASA
GLPVPAATERALELFHQHQADTLKIHSDFMRAQVLGSEQMLSALSGQTLVSQAPQTAAAV
VAAPVAAASQVMAAPVVKAPEAPVTAPVAAQVAAPMPAPAMVIPAAASVAALPIQDIMLQ
VVAAKTGYPTEMLDLSMDMEADLGIDSIKRVEILGTVQDELPTLPELDAATLAECRTLED
IVAYMHKVAGTSPVTAATSHSQAVPTPVSASADITAVMLKVVADKTGYPTEMLDLAMDME
ADLGIDSIKRVEILGTVQDELPMLPELDAATLAECRTLEDIVAYMHSMTGAAVSQAPVSQ
TAAPASHQAAHSSSDITPVMLKVVADKTGYPAEMLDLAMDMEADLGIDSIKRVEILGTVQ
DELPTLPELDAATLAECRTLADIVAYMHSMTGAAVSQAAVSQVAAQGATQSTQNSSDITA
VMLNVVADKTGYPAEMLELAMDMEADLGIDSIKRVEILGTVQDALPGLPEIDPSTLAECR
TLGDIIACYGTDGAQDATDNGKAEAQQTEADADTGIEVEVDIAVSALAAAQDIVASESAT
ASAFESDNATAAAAAATLPTPTPQQVLDTMLTVVAEKTGYPVEMLDLAMDMEADLGIDSI
KRVEILGTVQERLPGLAEVDAATLAECRTLGQIVESFSLPNQYVGTDASTDTELAPHTGV
ALKKLQAADRLEAPSATGLFAAKGRVIILDDGHNAGVLAGRLDAKGHAVTVIRCDSLGHQ
SVLDASIDARTLSQGGDMDTEIQSLIKALEPVSAFIHLQPVMAADDGAADVKATARFSDE
AFSQVSLAFLFAKHLAADFAAEGAHRRAFITAARMDGKLGLSGADVELNQAALFGLTKTL
AQEWPHTHCRALDVAAQLDATSLADAVIDALYGADDLLEWGIAADGRFAALATDAQQISA
KTALNSTDKILVTGGAKGVTLDCALALAARTHAHFILAGRSKALSLNEFPVWAKGVAATE
LKQAAIQELLAGGKRPTPKEVDALIAPLASALEIQQALQAFSDLGASAEYLSMDVSSAES
IAKALGPIQAIAPVTGLIHGAGVLADKFIQDKTLDELKRVAGTKVDGLKGLLANLDGLKL
VALFSSAAGFYGNKGQSDYAMANEILNKAAHRLAHAKPDCRVVAFDWGPWDGGMVTDSLK
KMFQERGVYVIPRPLGAALFAEAVLGRAESQILVGSSMQGNADQAGANLKKPEGHSGITL
GRTLYRPHLALLEDHQIGGNAVLPTVCALEWMQDAATRHFGGQWQPHDYRLLKGVVFDSD
EKALTMQLNVTDAGLSALISCDGRPQYEARLQPPSPLSLPSEAMAADIRQSADKAVVTGK
QLYQDGALFHGPALQMIGDVSWFDDGGLGCTVMLPAASVEPGQAAIIQQDALLQALLVWA
RLKYDAASLPASLTRAVQHLELSPGEQGQLRLWVKSHSSRQLCADVALYNAQGQLASAME
GVKVTISKSLNQAFLSAKGQEI
>G6G0G1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Fischerella thermalis JSC-11|TrEMBL
MNNFNEFNSFDDNDEIAIIGMVGRFPGANNVDKFWQNLRDGVESITCFTDEELVSAGIDS
AVLRDPNYVKAGSVLEDVDLFDASFFGFTPREAEITDPQHRLFLESAWEALENAGYNSET
YTGRIGLYAGVAFSSYFFTNLYPNRDLTQLVDDFQTFIGNDKDHLPTQTSYKLNLTGPSV
NVQTTCSTSLVAVHLACQSLLNGESDIALAGGVSIQIPQKAGYLYQEGGINSPDGHCRAF
DANAQGTVFGDGLGIVVLKRLADALADRDYIHAVIKGSAINNDGSLKVGYTAPSVDGQRE
VILEALALAGVEPETITYIETHGTGTPLGDPIEIAALTQAFRRSSDKKGFCAIGSVKTNV
GHLNTAAGVTGLIKTVQALKNKQIPPSLHFQQPNPQIDFANSPFYVNTKLTEWKTNGIPR
RAGVSSFGIGGTNAHVILEEAPVVEMCHGTSLHSRPWQLLVLSAKTSTALETTTANLIAH
LQQHPDLHLPDVAYTLQVGRRSFDYRRIVVCNSLEDAVKALTDQDPQHVFTHHHKPGQCP
VVFMFSGQGSQYVNMGRQLYEVEPSFKKHVDHCSEILKPHLGIDIRNIVYPTTQQREQAT
RQLQQTAITQSALFVIEYALAQLWMSWGVRPVAMIGHSIGEYVAATIAGVFSLEDALAVV
AARGKLMQQMPTGSMLAIGLGEQQVQPLLGEGLSLAAINSPSSCVVSGTTDAISELQKQL
ACQNIESRVLHTSHAFHSHLMQPMLGEFVQLLKNVQLNPAQIPLISNLTGTWINPHEATN
PEYWGQHLRQTVRFSAGISDLLQQHQGIFLELGPGRTLSTLTTQHLNGNQKQKQLVLTSL
PHPQQQQSDVAWLLQTLGRLWLFGVEIDWSVFHSHQQRQRLPLPTYPFERQRYWIEPQKQ
QQHHHHPTPPLGKKSDISQWFYIPFWKPSLLQTQLEVEQATPKSCILLFVDECGLGNKLL
KQLQQQNYDVISVKVAHNFTRLNESEYTLNPQQPDDYDALIQELFKQQKLPKKIVHLWSV
TPGCQQQLDFEKVEQAQTRGFYSLLFLAKALARQQTNDDFEITVISNHLQPVTPTELVSP
EKATLLGAIKVIPQEYANITCRSIDVIIPANGSWQEQKLVESLLGELSISSCEKVIAYRG
GNRWIQCFEPVRLEQVKSNTPRLKQGGVYLITGGLGGIGLVLAEYLATQVKAKLVLIGRR
AFPNQQEWSEWLLTHDHNDVISCKIRKLQQLQQLGAEVLVLAADVTDLQQMQQAIASAYS
TFGQLNGVFHAAGIVGGKSFAAIDKITKTDCEQQFQAKVHGLIVLEKVLKNTQIDFCLLL
SSLSSVLGGLGFVAYSAANNFMDTFVHQHNQNHPVSWISVSWDSWQLETENQQSTSLGAS
VSEFAFNAQEGVEALQRILNYSQFNHVVVSTGELQARIDQWIDLKSFPQQTNLLSLHPRP
DLQNPYVPLTNEIEQKIANIWQEVLGIKDVGLYDNFFELGGDSLLIIQVRNKLLKTLNKN
LSIADLFEYSTISALAEYLGEKQVEQPTFQQADERAKKKEEAMQEKRQLMKQRRKADG
>A0A2K8P9W6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces lavendulae subsp. lavendulae|TrEMBL
MNEEKLRYFLKRVTADLHETRRRLQEVESEEQEPIAIIGMSCRYPGDVESPEDLWRLVSE
ETDAISAFPTDRGWDTGSLFDEDPDGRGTSYVREGGFLHSANRFEPEFFGISPREAVAMD
PQQRLLLEIAWEAFERAGIDPTSVRGSRTGVFTGVMYHDYASRLRAVPPEVEGYLGTGGS
SSIASGRVSYTFGLEGPALTVDTACSSSLVTLHLAMQALRKGECSLALAGGVTVMPTPGT
FTEFSRQRGLSFDGRCKSFADAADGTGWGEGAGMLLVERLSDARRNGHRVLAVVRGSAVN
QDGASNGLTAPNGPSQQRVIRQALADARLTGADVDVVEAHGTGTTLGDPIEAQALLATYG
REHTEDRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAIRHGRIPKSLHVDEPSTKVDWAAG
AVSLLRTTVDWPDTGRPRRAAVSSFGISGTNAHTIIEQAPTEVPADAAATDAAGTESETG
TETGTETAETAAPQRRTVVPPVLPWPVSARTEAALRAQAERLLTHLRAHPDQSAADISRS
LATGRAALEHRAVVVAGDRDRALADLAALASEEETAATRVVRGEAGARGKTAFLFTGQGS
QRLGMGRELYDAYAVFAEALDAVCERLSLELPLKGVLFGTDAKLLDRTEYTQPALFAVEV
ALFRLLESWGVRPDFVSGHSVGEIAAAHVAGVLSLDDACALVSARGRLMQALPAGGVMIA
LEASEDEVLPLLTGRVSIAAVNGPRAVVIAGDEDAATAIVEAFPDRKSKRLTVSHAFHSP
HMDDMLEDFRRVVAGLTYGAPQIPVVSNLTGALVSDEMGSAEFWVRHVREAVRFLDGIRA
LEAAGVTTYVELGPDGVLSAMAQACLADDTGTAAFVPTLRKDRPEAETAVTALAHVHVHV
RGIAVDWQSYHRDTGAEHVDLPTYAFQREHYWLDAGTLGGDVTTAGLRSADHPLLGASVT
LADADGLLLTGRLSLPTHPWLADHRVMGSALLPGTAFVEFALHAGERVGCDLVDELTVAA
PLVLPEEGAVELQITVGAPDEAGRRPVVFHSRDSLAAYDEPWVRNATATLAQGAEEKQAC
DLNVWPPTGAAPVDIEGLYEGLADSGFGYGPVFQGLRAAWRRGEEVFAEVGLGDETDPGA
EQFTIHPALLDSALHAIGLGSLVEDTGRGQLPFSWSGVAVHSTGADTLRVRLSKAGQQSV
RLDMADIDGAPVATVDSLALRAFSPEQFGRPAGGHGDSLFGVDWTEAASAAAGSADTWMM
LGEGAQVFADLAGLGVAVVEGGEIPSALVVPCTEPAGADVAAAVHAETGRVLALVKEWLT
DDRFSGSRLVFLTRGAVEAVPGEGVSDLVHAPVRGLVRSAQSENPGRIILVDVDADADGE
VEQALSSALASGESEVAVRGGSVLVPRLARAAVAADAAPAWDAEGTVLVTGASGSLGGLF
ARHLVAEHGVRHLLLVSRRGEAASGAVELSAELAELGAEVAWAACDVADRDALAAVLAGI
PAERPLSAVVHTAGVLDDGVLGSLTAERLSAVLRPKVDATWNLHELTAGLDLSAFVLFSS
AAGVFGGAGQANYAAANTFLDALAAHRRAQGLAATSLAWGLWAEVGGMGGALDAEDVSRM
GRGGVNALTAAEGLALFDTACASGQALLAPVKLDLAALRAAAGGGMLPPLLSGLVRMPAR
RAARGGGGAFARQLAALPQEQQAGAVLGLVRGQVAAVLGFAGPEAVEPARSFSEVGFDSL
TAVELRNRLGAATGVRLPATLVFDYPTPAVLGEYLHAELLGSQEADTAPTAVAVHDDEPI
AIVAMACRFPGDVRSPEDLWRLVRDGRDAISDMPADRGWDLEALFDADPDRQGTSYSTAG
GFLHDAHHFDPTFFGISPREALATDPQQRLLLETSWEAFERARIDPASMRGSRTGVFAGV
MYNDYGTLLHRAPEGLEGYMGTSSSGSVASGRVSYTFGLEGPAVTVDTACSSSLVTLHLA
VQALRNGECDLALAGGVTVMATPGTFIAFSRQRGLATDGRCKPFAAAADGTAWGEGVGML
LVERLSDARRNGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLTSADVD
VVEAHGTGTTLGDPIEAQALLATYGQDRAADRPLLLGSIKSNFGHTQAAAGVAGVIKMIM
AMRHGTVPKTLHVDEPSPHVDWSEGAVELLTESVAWPETGRPRRAAVSSFGISGTNAHTI
IEQAPDEAAVAAAETDAAPAFPYVLSAKSTDALSAQAARLRTHLQDTPEAGAADMAYSLA
TRRAAFAHRAVIVAGAREELLGALAALENGDVTAAGITCGTVGAAGAGKLAFLFTGQGSQ
RLGMGRELYEVQPVFAAALDAVCERLELPLKKALFGADAGLLDETRYTQPALFAVEVALF
RLLESWGVRPDFVSGHSVGEIAAAHVAGVLSLDDACTLVEARGRLMQALPAGGVMIALEA
SEDEVLPLLTDRVSIAAINGPRSVVIAGDEDAAVAIAEAFPDRKSKRLTVSHAFHSPHMD
GMLDAFRRVAQGLTYAAPRIPVVSNLTGALVSDEMGSADFWVRHVREAVRFLDGIRALEA
AGVTTYLELGPDGVLSAMAQTCLADETRAAVFAPALRKERPETGTLTAAVAEAHAHGAPV
DWESYFAGTGARSIDLPTYAFQHERYWIDLPVGSFADAAAAGLRPADHPLLGASVMLADA
DGLLLTGRLSVATHPWLADHVVMGAVTLPGTAFVELALRAGEQIGCDLVEELTLAAPLVL
AEDGGVELQIAVGAPDEAGRRPLAFHSRDALAAESALWLRNATATLAVSAEEPPVFDLAA
WPPAGAEPVDVEDLYEGFAESGFGYGPVFQGLRAAWRKGDEVFAEVGLGDEQGPDAEQFT
IHPALLDSVLHAIGLGSLVEDTGLPRLPFAWSGVAVHSTGADTLRVRLSRAGREAVRLEI
ADTDGVPVASVDSLALRAFSPEQLGRQVAGHGDALFRVEWRELMPSDALFGDWIMRDEAD
AQALDDLDAVPGALVLSCPAPDGPDVADAVHAEAARVLALLQRWLSDDRFADARLAFLTR
GAVTVAPGDGPADLVHAAVWGLVRSAQSENPGRIVLVDVDADGDAEQALSAALASGESEV
AVRGGVLLVPRLARASVAGLDPEWDAGGTVLVTGASGSLGGLFARHLVAEHGVRNLLLVS
RRGEAASGAAELSAELAELGAEVAWAACDVADRDALAAVLAGIPEERPLSAVVHTAGVLD
DGVVGSLTAERLSAVLRPKVDAAWNLHELTAGLDLSAFVLFSSAAGVFGGAGQANYAAAN
TFLDALAAHRRAQGLAATSLAWGLWAEAGGMGDTLDAGDVSRMGRGGVIALSAAEGVALF
DSACASGQALLVPVRLDLAALRAAARGGMLPPLLSGLVRMPSRRAARGGTAAGGAFARQL
TALPQDQRPGAVLELVRGQVAAVLGFAGPEAVDPARSFSEVGFDSLTAVELRNRLAAATG
VRLPATLVFDYPTPAVLGEYLHAELLGGQGTDVAAVAASVHDDEPIAIVAMACRFPGDVR
SPEDLWRLVADGRDAISAMPDDRGWDLAGILDPGQPGADYSPTGGFLHDAHHFDPTFFGI
SPREALATDPQQRLLLETSWEAFERAGIDPASMRGSRTGVFAGVMYNDYGTLLHRAPEGL
EGYMGTSSSGSVASGRVSYTFGLEGPAVTVDTACSSSLVTLHLAVQALRNGECDMALAGG
VTVMATPGTFIAFSIQRGLASDGRCKPFAAAADGTAWGEGVGMLLVERLSDARAKGHPVL
AVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALANAGLSAAEVDAVEAHGTGTTLGDPIE
AQALLATYGQDRPAEQPLLLGSIKSNIGHTQAAAGVAGVIKMVQAIRHGVLPKSLHVDEP
TPHVDWSAGAVSLLESATPWPETGRPRRAAVSSFGIGGTNAHTIIEQAPDEAVVTAAETG
TAPVLPYVVSAKSADAVRDQAARLRRHLEGAAGLRPADVALSLATTRAVFDHRAVVVAGD
RKELLRGLTALEDGTAAAGVTRGAVSTGKTVFVFPGQGSQWLGMAAGLLESSPVFAARIG
ECAKALEPFTDWSLVDVLRAADGAPSLDRVDVVQPALFAVMVSLAEVWRAAGVRPGAVIG
HSQGEIAAACVAGILSLEDAARVVALRSQAIGRVLAGLGGMVSVPLAAAEVRERIAPWGE
ERISVAAVNGPSSVVVSGEVQALEEFLAACETDGVRAKRIAVDYASHSAQVELLREELDT
LLAPIAPRAAGVPFLSTVTGEWVEGPELDGGYWFRNLRRTVELERATRTLLDQGFGVFIE
SSPHPVLTVGLQETVEDAGREAAVLGSLRRGEGGLERFWLSLGEAYVRGVTVDWDAVFAG
TGAQRVDLPTYAFQRDRFWIDVPVSAVGDVASAGLGKAEHPLLGAAVELPDSDGFLFTGR
LSLTTHPWLADHRAAGAVLLPGTAFVELALHAAQRAGSTVLEELTLEAPLVLPERGALQL
RLSVAAPDADGRRALHVYSRPEARHGEDGRGSESEPWTRHAAGVLGAADTPAAAPAPAPR
TWPPAGADELEVDDLYELFAAGGYAYGPAFRNLRAAWRLGDELFAELSLAEGPQADAAHF
GVHPALLDAGLHGLALGSFLTADDEEPGAEARMRLPFAFTGVGLHAVGADALRVRLAPAG
SGAVSLTAFDEQGEPVVSVESLLLRTLDPAALTSARSAFHESLFRLEWPVVPAAAADPAA
TAGRWALVGPDTLGLEAALRGADATADVYGDLDALGAVVTAGQPAPDTVLVTYAMPGAGA
AEGPQDTAGAARQATRDALALVQAWLAEEAFAGSRLAVLTRGAVEALPGEGVADLAHASV
WGLLRSAQSENPGRFLLIDLDAGADAARAEHPALLAAAVASGEPQLALRGGALHAARLAR
VRAERPEPQEAAEEGAAAEAARPVPVPVPVPDPDGTVLITGGTGVLGSLLARHLVTEHGA
RRLLLTSRRGPRAAGAAELVAELAALGAEAAVVACDASDREALAALLAGIPAEHPLTAVV
HTAGHLDDGLVPSLTPERIDSVLRPKVDAALHLHELTRDLDLAAFVLFSSAAGTLGSPGQ
ANYAAANAFLDALAHSRRAEGLPAVSLAWGLWEQRSEMTGELTDADVQRMARAGLAPLTS
EQGLALFDTACGPAAGSVFLAIRLDTAPLRAQAESGALPAVFRGLVRGGLRKAAAHGAGT
AAASAAAQLLAGLSALPEEEQERVLLDVVRAQAAAVLAYPSPEAVGESQEFLELGLDSLT
AVELRNQLNAATGLRLPATLLFDHPTPLLVAQRLRAELAEGPGVPAGAAGTAERDAEEDA
GVFGAMLQEAGTQGASGQFMELLMQASRFRPSFSSAAELRRAPALVRLARGEEGPGLVCF
SSILSISGPHQYARFASAFRGRRDVHAMAAPGFLRGEQLPSTAGAVIEAQAEAVLRHTDG
APFVLLGHSSGGMLAHAVAGRLEDAGVFPEAVVLIDIYSHDDDAILGIQPGLSEGVDERQ
GSYVPVDDSRLLAMGAYFRLFGGWKPQAVKSPTLLVRAEERFFDWKRAATGDWRSYWDLE
HTAVDAPGNHFTMMEQHAQETAGAVGQWLDARS
>A0A2K8P6U4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces lavendulae subsp. lavendulae|TrEMBL
MTTDVNKLRDYLKRATVDLRHAHRRLREAEGKNREPIAIVGMSCRFPGGVRSPEDLWDLV
ASGRDAISGFPTDRGWDLDALYDPDPENPGTSYAKEGGFLYDAAEFDPAFFGIGPREALA
MDPQQRLVLEASWEAVERAELDPLSLRGSRTGVFAGVMYHDYVSRLPAMPEGIEGYVSTG
NTGSVVSGRIAYTLGLEGPAVTIDTACSSSLVALHLAVQALRQGECDLALAGGVTVMAGP
TTFVEFSRQRGLSPDGRCRAFSASAEGTGWSEGVGMLLVERLSDAVRLGHPVLAVVRGSA
VNQDGASNGLTAPNGPSQQRVIHQALANALLSPSDVDIVEAHGTGTTLGDPIEAQALLAT
YGQDRPADRPLWLGSVKSNLGHTQAAAGVAGIIKMVQALRHGVLPKTLHAEEPTPHVDWS
AGAVSLVTENAAWPDTGRPRRAGVSAFGVSGTNAHIVVEQHLAPAARPEAAAMDDAGPDA
PSVAAPAADGPSGAPGTATADGNGLPLVPWTLSGKTAAALTAQAARLRSHLAAPRPGPDP
ATDPAAGPAAYPAAGPAAYPAAGPAAYPAAGPAAYPAAGPAADPDAGPAADPDALDIAYS
LATTRTAFPHRAVLLAPDRAGLDRALDALADGEPDAAGAALVRGTSDATRQVAFVFPGQG
SQWAGMAVELLDAAPVFRERFRQCEEALAPHVDWSPTEVLRGAPGAPGFDRVDVVQPVLF
AVMVSLAELWRSHGVHPSAVAGHSQGEIAAACVVGALSLADAAKVVALRSQALTALSGRG
GMLSVALPLEDLTPRMAHWGERLSVAAVNSPTSIVVSGDRDALTELRDALHADDVRARLI
AVDYASHSAHVEAVRERVLDALAGITPQACDVPFYSTVTGTVVETDGLDAEYWYRSLRRT
VRFEEATRALVRDGHDALIEVSAHPVLTIGIQETLDDLGAGAVTLGTLRRGEGGPGRFLR
SAAEAHAHGVAVDWAAVLSGTGARRVALPTYAFQHERYWLDAPPAAADATGLGLASSDHP
LLGAVVSLADSDGLLLTGRLAAHTHPWLADHVVLGAVVLPGTAFVELAVRAGDHVGCDRL
AELTLQAPLVLPERGGVVVQVAVGPAEGTGERTFTIHSRPDTAAPEDGWTCHGTGVLTSA
AEDRPPVPAPAAWPPAGAAPVDLGGFYQELAARSFAYGPAFQGLRAAWRLGDEVFAEAVL
PPDASAPSDAARYGLHPALLDAALHGVGFGPLGDMGTGRMAFSWEDVRLYATGATRLRIR
LTPVGAEAVAVTATDDSGRAVATVAALTFREVREEHLRAALTDHHESLYRVDWPTLPPAG
TAPDDSTHWAVVGVTPRADADAVADALRGAGPRPDVHPDLAALAAAITEGAPVPRTVAAV
VPVAASDASDASDADTVRATARATLALVQAWLADERFVSSRLVVLTRDAVPVPSGAEDRV
PRTRPAHAPVWGLIRSAQSEHADRLVLADTDGEPESLRRLAAAVATGEPQLALREGRMSV
PRLARVPVTAGTAPARALDPHGTALITGGTGALGRLVAAHLVTAHGVRNIVLTGRRGPDA
DGADALREELAALGATVTIAACDAADREALAALLATLPADRPLTAVVHAAAVVAGGLVDT
LTPEELHQVLRPKVDAALNLHALTRDLDLSAFVLFSSFAGTLGGAGQAAYAAGNAFLDAL
AHQRRAQGLPASSLAWGVWDERGDQTRLETGDLRRMARAGLVPLGAEEGLRLLDTARTLD
DAALAPVRLDLAAMRAQAAAHPVPHLLRGLIRTPARRSAETAPGPGGHSAELSRLAALPP
AERRDTVLALVRNQVAAVLGHSAPEAIDPGRAFRELGFDSLAAMELRNRLATATGVRLPA
TAVFDHPTPAALAGHLLDEIPGGHPGTALVTAAPDASTTPGRLPGTDTDEPIAIVAMSCR
LPGEVRGPEDLWDLVANGTDAITGLPVNRGWDLDALYDPDPDHPGTSYVREGGFLHDAGD
FDPEFFGISPREALSMDPQQRLLLETAWEAFERAGIDPAALRGSRTGVFAGTNGQDYAVG
LSQHRTEDMEGHLLTANSASVVSGRLSYTFGLEGPAVTVDTACSSSLVALHLAAQSLRRG
ECDLALAGGVTVMSTPGALIGFSRQRGLSHDARCRAFSAAADGTGLAEGAGMLLVERLSD
ARRNGHRVLAVVRGSAINQDGASNGLTAPNGPAQQRVVRQALTDAGLTAADVDAVEAHGT
GTTLGDPIEAQALLKSYGNDRPADRPLWLGTVKSNIGHTQAAAGVAGVIKMVMAMRHGVL
PRTLHVDEPSPHVDWSAGAVRLLTEPVEWAEHGRPRRAGVSSFGVSGTNAHVIIEQAPAE
GADGTNHGPGEETGPRPAVPWLISAKDETGLRAQAERLLGHVRSEAHGTDETDIAFSLAT
TRAAFPHRAAVIGADRELLVQGLTALAHGEPSGTETVRGTATASGSRTAFLFSGQGSQRP
GMGRELYAAFPVFAGAFDAVCAALDAHLERPLKEVVFGGDAGLLNQTGFAQPALFAVEVA
LFRLVESWGVRPDFLAGHSVGEFAAAHVAGVFSLEDAAALVAARGRLMQALPSGGVMVAV
QASEEEVRELLSGYEDRAGVAAVNGPSSVVVSGAEEAVAALVDRLSADGRKTKRLTVSHA
FHSPLMDPMLDDFRKVAEGVSFGDPTVPLVSTLTGAPVPAEEFCSADYWVRHVREAVRFA
DAVTSLADLGVRTFLEVGPGGALTSMAQDSLDEHAVSVPLLRTDRAEDLAVTTALARLHV
HGVPVDWTGVFAGRGARRTDLPTYAFRRTPYWLLPADPQETGPLSADPADAGFWEAVESQ
DLASLTEQLDLDGDSPLSSVLPALSRWRRRQRDASVVDALRYRTSWKPLTGREAAELTGA
WLLAVPAGAEDAPTVAAVTAALSRQGAEPVPLVVRADEDRAALAARLRAQPGDTAPAGVL
SLLALAEEPHPVHKELPTGLAQTTLLVQALGDAEISAPLWCVTTGAVTVGRSDPLTSPGQ
GMVWGLGRSVALEFPERWGGLVDLAGAPDERTARRLASVLSAPAHASAAPADDQIAIRPS
GIFVRRLARALTGAVPADGAWQPRGTVLITGGTGALGARVARYLAARGAEHVVLTGRRGP
DAPGAAQIAEEIEALGAEVTLVACDVSDREEVAALLRSVPEDRHPLTAVVHAAGMPQFAP
TDSLDLGDFAEVVSAKVAGASHLDELLGDRPLDAFVLFSSVAGVWGSGRQAAYAAANAFL
DGLAERRRADGLAATSVAWGPWADGGMADDDEAEAHLRRRGLPPMSPDTAIAALQRALNH
DETTVVVADVDWDRFAPAFTIARPAPLLADLPEARQALAGTGSATGGDGRPDTTAPSLGA
GLAALAEPERRRALLDLVRTEVARALGHPGRDAVASDRSFKDLGFDSLTAVELRNRLNAA
TGLRLPTTLVFDHPNADALADHLTSELPGHGAATVRADAATPGERPAATPDEPIAIVAMS
CRFPGGAHSPEQLWQLLVDGVDTVSAFPADRGWNLDTLYDPDPEHPGTTYVNEGAFLYDA
GHFDSTFFGISPREALAMDPQQRLLLEAAWEALERARLAPSSVRGTRTGVFIGSGYQGYG
AGPGDLPDGVEGHLLTGASSSVMSGRISYALGLEGPAMTVDTACSSSLVALHLATQALRQ
GECELALVGGAAVMSSPSAFVEFSRQRGLAADGRCKPFAAAADGTGWGEGVGMLLVERLS
DAQRNGHPVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIRQALANAGLSTADVDAVEAHG
TGTALGDPIEAQALLATYGQDRPDDRPLWLGSLKSNIGHTQAASGVASVIKTVMALRHGM
LPKTLHVDEPSPHVDWSAGAVRLLTEPVTWTGNGRPRRAAVSSFGVSGTNAHTVIEEAPA
TVPTEEGEHGTPAAGHCLPWTLSGKDEASLRAQARNLLAHTSDHPNLAPADLALSLAESR
TAMTHRAVVLGRTTAELAAGLEALSKGETATDLVRGVARPADRRTAFLFPGQGSQRLGMG
RELYAAFPVFADAFDAVCAHVDQYLERPLAGVVFGEDAALLDRTGYAQPALFAVEVALFR
LVESWGVRPDALAGHSVGEFAAAHVAGVFSLEDAAALVAARGRLMEALPAGGVMVAVQAS
EGEVRDLLSGFEDRAGIAAVNGPSAVVVSGAQDAVTKVADRLAADGRKTKALSVSHAFHS
PLMDPMLDDFRKVAEGVSFGVPTLPVVSTLTGAPVPAEEFCSAEYWVRHVREAVRFADAV
TSLADLGVRTFLEIGPGGVLTAMAQAALEDGPAVVPVLRADRPEEVAVTTALARLHVHGT
PVDWSAVLAGRGARRVDLPTYAFQREHYWLETAIAPAAPAHQPSGSDNPAETEFWEAVEN
GRPEALAERLGLAEGAPLDSVFDALATWREESRNRSTLDGWRYHTVWQPLADPSSGPLPG
SWLVVAPDAGAAEPYARTLRDRGAEPLCVTVADPAADRSALVELLRDAVAEHSGPVSGVL
SLLALDERSHPTHPGLPAGLTATVALVQALGELEPDAPLWCVTAGAVSVSGAQPVTRPLQ
SLVWGLGRAVALETPQRWGGLVDLPTAPDGRALARLADVLADAAGEDQLAVRASGVLVRR
LARMPRATGGTDGAWKPRGTVLITGGTGSLGGHTARWLARGGAEHLVLTSRRGEAAEGAL
ELAAELGALGARTTIAACDVADRAALAALLDGLADDPAPLTAVVHAAGLPQFSPVADTSL
TELAAVVSAKVAGAVHLDELLADRELDAFVLFSSVSGVWGSGSQAAYSAGNAFLDALAQH
RRARGLAGTAVAWGPWAEGGMAADGGAEEYLRRSGLPSLPPALAVSALQLAMDRDETTVV
VADVDWPRFAPSFTIGRPSALLAALPEARAALDSGGADGGPGGDRGEGAASDLVRRLPAG
APEDRHELLLELVRKEAAAVLGHPRTDAVEPDRAFRDLGFDSLTAVELRNRIGTATGLRL
PMTMVFDHPTPTALTDRLLGDLFPGGADGPHPDAGPDEARVRQTLASIPLSRLREAGLMD
ALLALAPGAPGGVATDTGTDGDADSAIAEMDLENLIELALGDSEA
>A0A100J407|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MNGVDVALTAGGTDADEIAVVGLSCCLPKAAGPAEFWRLLREGVDATGEAPDDRWAGASH
SPRRGGFLDRIDQFDADFFGISPKEAVAMDPRQRLLLELSWEALEDARIVPTALRGSRTG
VFVGAMGDDYAVLMSRLGQEAIGEHTLTGASRAIIANRVSHFLGLRGPSLTVDTAQSSSL
VAVHMACESLRRGESTVAIAGGVNLNILAETTVGAQKIGALSPDGRCYTFDARANGYARG
EGGVVVVLKKLADAVADGDKIYCVIAGGAVNNEGDGDGDGCGLAVPSRSAQADVIQEAYR
RASVDPAEVQYVELHGTGTKVGDPVEAAALGAALGTRRPAGSPLLVGSAKTNVGHLEGAA
GITGMLKVVLSLRYRLLPPSLNFVAANPDIPLDELRLRVHTRLAEWPEQGRRLVAGVSAF
GMGGTNCHLVLAEAPVRISEGESESAASAVPVPSVVPWVLSGRSESALRGQARRLVEYVE
GDAGLDLVGVGAALVSTRASFEHRAVVLGAGRDELIAGLAGLAAGEPGAGVVAGQGVAGG
RGVVFVFPGQGSQWAGMARGLLVSSPVFAERMRECAQALAPFVEWDLLEVLGDEGALGRV
DVVQPVLWAVMVSLARVWESLGVVPAAVVGHSQGEIAAACVAGGLSLGDAAKIISVRSRL
LAESLAGRGGMVAVRLPLAGVELLVARWEGRLSVAAVNGASSVVVSGDAEAVTELVLVGE
AEGFRTRRMDTDCAGHSPHVEEVRAELVEALADIAPVEGSVAFYSTVTGELADTRGLDAE
YWYRNARETVRLADTAGVLTAAGYGVFVEVSPHPVLVPSLEETLFESHSAAVVTGTLRRG
EDESEQLLVAVGRLHTCGVSVDWSAVVGRGSVVDLPTYAFQRERYWPEAVSGSVVGGVDD
ELWSVVEGADVGLLSAELGVGEGALGEVVPALAAWRERRRAGSVVEGWRFAESWKLLPGV
PGGVLPGRWLVVVPAGWGEDAWVAGVIGALGAGVVRLEVDEDTDRAALAGRLVDLPELAG
VVSLLGVAEEACSGFGATPVGLAGTVGLVQALGDCGITARVWCVTRGAVSVGSGDRVVSP
VQAALWGLGRSVALDLPVRWGGLVDLPVAVDERIGGLLRRVLTGDEDQVAVRESGVYGRR
LVRAGAGAGGGVAGAGVRLSGSVLITGGTGGLGGHVARWAVARGAEHVVLVSRRGLEAPG
ASGLREELMALGARVTVEACDVADREALAGVLGRVPAEFPLTAVVHAAGVGDGHVPVGEL
ELERLDGVLRAKMVSAWHLHELTAGLGLQAFVLFSSGAASWGAGGQAAYAAANAFLDGLA
GYRHGAGLAATSIAWGLWAGPGMGAADVEGYRQRGVLAMEPELAMAALERAVGEGSVTLT
VTDTDWERFAPSFTVERPSALLSGIPEARKALARPGGESALRRRLAGLGERERARALLDL
VRREAAVTLGFDNADALPDGRAFRDIGFSSLTEVELRNKLASATGLALPASLVFDYPTPA
VLAEHLGSELLGSEAQVVVPVVVKAEPDEPIAIVGMGCRFPGGVSSPSDLWALLAGGVDA
ISAFPTQRGWDVVGDGFARVGGFVEDVAGFDAGFFGISPREALAMDPQQRLLLETAWEAL
ERSGIDPNLLKGSRTGVFVGGTDSSYDTVGEASAELDGYRLTGGSSSVLSGRIAYVLGLE
GPAVTVDTACSSSLVALHLAVQALRSGECSMALAGGVTVMATPEVFAQFAAQDGLARDGR
CKAFAASADGTGWGEGVGLLVVERLSDAQCNGHQVLAVVRGSAVNQDGASNGLSAPNGPS
QQRVIRQALASAGVAAAEVDVVEAHGTGTRLGDPIEAQALLATYGQDRPEDRPLWLGSLK
SNIGHTQAAAGVAGVIKMVLAMQQGVLPRTLHVDEPSPEVDWSVGAVELLTEQRSWPVVD
RPWRAGVSSFGVSGTNAHVILEQAPEVEPAVRVEVVPSVVPWVLSARSELALREQARRLA
AYVEADSGLDPVDVGAGLVSTRASFEHRAVVLGTGRDELIAGLAGLASGELGAGVVTGEV
GQSVAGEQGVVFVFPGQGSQWVGMARGLLVSSPVFAERMGECARALAPFVEWDLLEVLGD
EEALGRVDVVQPVLWAVMVSLAQVWRSFGVVPAAVVGHSQGEIAAACVAGGLSLDDAARI
SAVRSRMIAGSLAGRGGMVSVGLPRAEVELLIVRWEGRLSVAAVNGPSSVVVSGDPEALA
ELVVAGEAENFRARKIEVDYASHSAHVEEIEAELVEALADIAPVEGTVAFYSTVTGELTD
TRDLDAEYWYRNLRETVRLADTTRALAAAGHGTFVEVSPHPVLTPSLEETLFESHPSAVV
TGTLRRGENELEQLLAAAARLHTRGVPVDWSAVVGRGSVVDLPTYAFQRERYWPRPRAAA
GDVRGAGLVSLSHPLLGAAVELAGGEGVVFTSRLSLASHDWLADYLVNGVVVVPGTAFVE
LLVRAGDEVGCGVLEDLALERPLVLSERGAVQVQVVVGAPAESGRRAVSVYSRPEETAAE
AGWTRHASGALASEPTMPSGAELTVWPPAGAEPVPVDDLYDGLADAGYGYGPSFQGLRAA
WRRGEEVFAEVRLPGEVTDRAGEFGIHPALFDAALHAAVFLPGDVEGGLPFAWSGVSLHA
SGAQSLRVQLSVIGDGGLRLNAVDDTGAPVVSVDSLTLRPVWSELLGSGDERRSLFGVDW
VVLPGVGDEASAGSWAVIGAGELEVESLGVPCYAGVGDLVGAGVPVPDVVVVACVGSLEG
DRGVDARVLTGRVLGVVGEALAEDRLSGSRLVVVTCGAVAAGVGRDVSDLAGGAVWGLVR
SAMSEHPGRLVLADVESFVADVPVVVGLVGGDEPEFAVRGGRVLVRRLARPDAGALTLPA
GDGWRLGAEIVGTPDGLAFVPDVGGAAELADGQVRVEVRAAGVNFRDVLVALGVVSADAL
GLGGEGAGVVTEVGPGVTGLVPGDRVMGVLADAFAPVVVADHRTLVPVPEGWSFTDAAAV
PVVFATAWYGLMDVAGARPGERVLIHSAAGGVGMAAVGIARHLGLEVFATADPAKHDALV
AMGVAPDHIASSRSAEFADRFAGMDVVLNSLTGELVDASLRLLRDGGRFVELGKADVRDA
DAVAAEYPGVRYEAFDLLSAAGPERLGRILVECVGLLAEGVLSRLPVMVRDLRQAPEVFR
FMSRGEHVGKIVLRVPGGLVGDGTVLITGGTGTLGGLLARHLADRHGVRHLTLVSRQGMA
APGARELVGELAELGAGVRVVACDVSDRDAVAELVAGVSVEHPLTAVIHTAGVLDDGTIT
SLTSERVDTVMRPKADAAWYLHEATAGLDLAAFVLFSSFAATCGAPGQGNYAAANAFLDA
LALHRHALGLPATSLAWGWWADASGMTGGLGQSDHVRLGRAGVRAMPAAEGLALFDLACR
RPEAYLVPVRLELPRQGGSEPVPPLLRGLVAGGRARPVARAGDRDGSGLAGRLAGLTGDD
QQRLLLDLVCGHVATVLGHASAGVVDPEKALRDMGFDSLTTVELRNRLAAVTGLRLPATL
VFDHPTVSRLATHLRQQLTGTVEAAPVAPVVVKAEPDEPIAIVGMGCRFPGGLSSPEQLW
DAVMSSADVVGEFPADRGWDLVGDGFARLGGFVEDVAGFDAEFFGISPREALAMDPQQRL
LLETAWEALERSGIDPHALKGSRTGVFVGGAGFGYDTVGEASDELDGYRLTGGADSVLSG
RIAYVLGLEGPAITVDTACSSSLVALHLAVQALRSGECDLALAGGATVMSAPRIFAEFAV
QDGLAADGRCKAFAASADGVGLAEGAGLVAVERLSDARRNGHRVLAVVRGSAINQDGASN
GLAAPSGPSQQRVIRQALASAGVTTAEVDVVEAHGTGTRLGDPIEAQALLATYGQDRPAD
RPLWLGSLKSNIGHTQGASGVAGVIKMVLAMRHGQLPRTLHVDQPSTEVDWSVGAVELLT
EQRPWPVVDRPWRAGVSSFGISGTNAHLILEQAPEVEPASDVDVVAPVVVPWVLSARSES
ALREQARRLVAHVEADPGLDPVGVGAALVSTRASLEHRAVVLGTDRDQLIARLAGLAAGE
PGAGVVTGRAGQSTAGGRGVVFVFPGQGSQWAGMAQELLTASPVFAERMAECAQALAPFV
EWDLLEALGDQEALERVDVVQPVLWAVMVSLAQVWQSLGVTPAAVVGHSQGEIAAACVAG
GLSLDDAARIVAVRSRLLARSLSGHGGMVSVRLPLVEVESLIARWEGRLSVAAVNGLSWV
VVSGDAEAVTELVVAGEAEDFRARRMDTDCAGHSAQVDEIRAELVEALADIAPVEGTVAF
YSTVTGELTDTRELDAEYWYRNLRETVRLAETTPVLATAGYGVFVEVSPHPVLVPSLEET
LFEPHPAAVVTGSLRRDENELEQLLTALSTLHTHGVPVDWSAVVGRGSTVELPTYAFQRE
RYWPRPRAVAGDARGMGLTSLSHPLLGAAVELAGGEGVVFTSRLSLASHDWLAGYTVNGV
VVVPGTAFVELLVRAGDEVGCGVLEDLALERPLVLSERGAVQVQVVVGAPAESGRRAVSV
YSRPEESAEAGWTRHAGGTLASEAAVSAGAELTVWPPADAVAVPVDGFYEDLAETGYGYG
PAFQGVQAVWRRGEEVFAEVQLPDEVAERAGEFGIHPALFDAALHAAVFLPGDVEGGLPF
AWSGVSLHASGAQSLRVQLSATEGGALRLSAADDTGAPVLSVDSLTLRPLRAELLESGDE
QRSLSSLPRHGGRARPVARVGVRDGSGLAGRLAGLTAADQQRLLLDLVCGHVATVLGHAS
SGAVDAEKALRDMGFDSLTTVELRNRLATATGLRLPATLAFDHPTASRLATHLRQQLLGT
VEAAPVVPVVVKAEPDEPIAIVGMGCRFPGGVSSPSDLWALLAGGVDAISAFPTQRGWDV
VGDGFARVGGFLHEAAEFDAGFFGISPREALAMDPQQRLLLETAWEALERAGIDPDVLKG
SRTGVFVGGAGSGYDTVGEASTELDGYRLTGGAGSVLSGRIAYTLGLEGPAVTVDTACSS
SLVALHWAAQALRAGECDLALAGGVTVMATPGVFAEFAIQGGLAADGRCKAFAAAADGTG
WAEGVGLVAVERLSDARRNGHRVLAVVRGSAVNQDGASNGLSAPNGPSQQRVIRQALASA
GLTAAEVDVVEAHGTGTRLGDPIEAQALLATYGQDRPADRPLWLGSLKSNIGHTQGAAGV
AGVIKMVLAMQQGVLPRTLHVDEPSPEVDWSAGAVELLTEQRSWPVVDRPWRAGVSSFGV
SGTNAHLILEQAPEFEPVSDVVVVPSVVPWVLSAGSELALREQARRLAAHVEADSGLDLV
GVGAALVSTRASLGHRAVVLGADRDELIAGLAGLASGEPGAGVVAGVSVAGGRTAFLFTG
QGAQRVGMGRELAAEFPVFAEAFGEISAGFEGLLPGSLEEVVFGGDEYRLTETGWAQPAL
FAFEVAMFRLLSSWGVAPDFVVGHSVGELAAAYVAGVWSLPDACRVVAARAGLMQALPAE
GVMLAVEASEAEIVSVAGEVAGWGERAAIAAVNAARSVVLSGDAAVVGAMGELWRGRGRK
VRRLRVSHAFHSPLMDPMLDAFADVLGGVEFNEPSTGMTIPAAQVCSAEYWVRQVHEPVR
YADMLAELGVQGVTRFVEVGPDGVLSGLGSGAVDGLFVAAQRRDRPEIHTAMTALSTLHT
HGVPVNWPAIVGRDSTVELPTYAFQRERYWPRSRAVAGDVRGAGLVSVGHPLLGAAVELA
GGEGVVFTSRLSLASHDWLADHAVRGVVIVAGTAFVELVVRAGDEVGCGVLEDLALERPL
VLSERGAVQVQVVVGAPAESGRRAVSVYSRPEETAAEAGWTRHASGTLTSESTMPTGAEL
TVWPPAGAEPVPVDDLYDGLADAGYGYGPAFQGLRAAWRRGEEVFAEVRLPDEAAERAGE
FGIHPALFDAALHAAVFLPGDVEGGLPFAWGGVSLHASGARSLRVRLSVIGDGALRLSAV
DDTGAPVVSVESVELRPVWSELLEAGDERRSLFGVDWTVLSGVGDEVPAGSWAVVGADGP
GLESLGVPCYAGVGDLVGSGVPVPDVLVVACVGSLEGDRGVGARVLTGRVLGVVRQVLAE
ERLGGSRLLVVTCGAVAAGVGEGVSDLAGGAVWGLVRSAMSEHPGRLVLADVESFVGDVP
VVVGLVGGDEPEFAVRGGRVLVRRLTRPDAEALTLPVSDGLVGDGTVLITGGTGTLGGLL
ARHLADRHGVRHLTLVSRQGMAAPGARELVEELTGLDAQVRVVACDVSDRDAVAELVAGV
PQAYPLTAVIHTAGVLDDGTITSLTPERIDTVMRPKADAAWYLHEATAGLDLAAFVLFSS
FAATCGAPGQGNYAAANAFLDALALHRHALGLPAVSLAWGWWADASGMTEGLGQSDHVRL
GRAGVRAMPAAEGLALFDLACRRPEAYLVPVRLELPRQGGSELVPPLLRGLVAGGRARPV
ARAGDRDGSGLAGRLAGLTGDDQQRLLLDLVCGHVATVLGHASAGVVDPEKALRDMGFDS
LTTVELRNRLAAVTGLQLPATLAFDHPTASRLAGYLHTRLAPTADADSAEARLREALASI
PLTRLRDAGLMDVLLRLAGASEDAPTNTEKQLDEMDAAALIDFVLDERN
>D0LS42|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2)|TrEMBL
MSDSRFEKLSAIKLAVLARQLRDEVDGIDALDAEPLAIVGMGCRFPGGANTPAAFWDNLV
AGRDVVTEVPADRWNIDEYYDPDPAAPGKMSTRWGGFVDEVDTFDPLFFGIAPREANDMD
PQQRLMLEVAWEALEHAALHPDEIYGSQTGVFVGASTTDYAQRQIASGTAPYLDKYFSTG
AANCFCAGRVSYTFGFQGPSVVLDTACSSSLVAVHLASQSLRRGECEMALAGGVNLMLSP
LLTIFTSKLQTMAPDGACKTFDTRANGFVRAEGCGVVVLERLSTALAKGHTIHALIRGTA
INQDGRSNGLTAPNVVAQQRVIERALANAHVNPARVTYVETHGTGTALGDPIEFEALQAA
YDRRDAAPCALGALKTNMGHAETAAGIAGLIKAVLSLRHQTLVGNLHFEQINPNIPLADT
RFAIPLETAPWQSEGPRMAAVSSFGFSGTNAHVVLEEMVQRPSEAPAERPAYALRLAAKS
PRALQALSERYAAFIESTEQPLAAVCATANLYRSEFPYRLAVAGANGEDLAAALRARDTE
PVAAKSRPKIAFVFSGQGSQYAGMGRELYEHEPVFREAIDHCERLLQPLIERSLLSLLYP
AEGETSPIDETRYTQPALFALQYALLQLWRSWGVEPDLVLGHSLGEFAAAHAAGMLSVED
GLRLVVERGRLMHEFADPGRMYAILAPEAQVAECLAAFAGEVVIAAVNNPEEVVIAGPPE
RAAEAAAACRERGLSTRDMDVQQAFHSPCMDPVANAFAEFVRNDISLASAKIPLISNIGG
SAKVDMSQPEYFARQIREPIRFADCVAQLAALGCEAVVEIGPRRTLLGLIQRCQPDAAWL
CAPSLHRKKSDLVQMLASMGKLYERGAAIHWQAVEHLESFARAELPTYAFDRERYWVTPP
AEMPRRATAAPAPEGPIDDEVGRMTSYYREVVHRVGEESAEDEAPFLRFPAFRQVVPGFS
SVRLLSRREANDAEHLELVRVAQDEMNRVIFRGIDMEYIHSILDIGCGQSRDIIDLAKRH
THLRAHGCNISVDQIDIGRKKLRSAGLEQRIQLFYQDSSKDEFPGAYDLAMSFQVMHHIR
DKSAALANISRHLNNGGFLVMAEIASRMSTPIEHNDSTAFFVPLDEWAEMLADNGLRVLD
CVDAAPEVSNFLFDADYDANFAVASAGMDDVSKAHLHGPHMLGWLFRRKLAAYMVMRVQR
DAYSTRNDLLACNRARLSNLLPYAQAIQALDGDSEAASWAQGTGRTPMPNAPAEAPERPR
VLDHAMLLSLPREERQQRVLETVRAHTARVLGIAETRLDQNTELPELGLDSLMLLELKNG
LDKELSVEIPSMELLRNPSVASLARFLVETIEGSAQPLEDAEEVSAWEEGEL
>A0A2S8JUB5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Escherichia coli|TrEMBL
MDNAAIISGYSVWMPYAEDCSQLIDNLKQGKRVARTPWFTSNEEAIKCGFKGNPSVATLK
QVDDSALDLLSQLIDEALEQAMLDKHCLAGRNVRVYLTGIGPRIDGLDYKSFYNYNDVED
INLTQSITNLHASKMSQDTISSHLARKYRLQYLPPNMNCTSNSSLTAVHLATQGIEQGGI
DLAIVLNCSKIKTQDIWFLETQSMLDSEQVQPFGENSKGVVFAEGFSALLLESAHHRRAR
QQSEGVRVQTTYTQISAGRSNDASWLSTNVHKVMQAAMKQAEIALDDLAAILPHGNGSAV
SDNAEAKAITMFAGERRIPVLAYKGQIGYTATGSGVVDLIIGHHSLTHYQLIAPVGNDVI
IDSMASLVLTDGSVTNHSKRHLLKVGVGVDGSVIGVVMTNMQAGRAK
>A0A655EV37|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGEQDASA
LIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTSVLESL
RDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVESAIRCG
ARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSAAVADP
GYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMVPSTPV
AGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDAVRAAG
ALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQVDAADAVPSAGQAALAAMHRSIGFEHP
EQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSVNGYTLFERTLADAPAVPNWSL
DSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAMLRKQHGTVIVSP
PCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNFAAKVLGLAQMI
ELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRHCVAVKWGLWQA
PKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAADAARLQMLLDS
RQFERYEGPTDPNLTIVDAVRTQLAAVLGIPQAGEVNLQESLFDLGVDSMLALDLRNRLK
RSIGATVSLATLMGDITGDGLVAKLEDADERSHTAQKVDISRD
>A0A2X4YF42|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Klebsiella oxytoca|TrEMBL
MDRKSIISGYSVHLPFADDSSQLIANLKQGKRVKTAPWFKSNDEAIKCGLRGNVNAAKMK
YSNDSIPELLYRLIDEALKQSMLDENCLREDNIRVYITGIGPRVDAIDYRSFATYNDIED
LALTPSITNLCARNMSQDIIAELLAKKYRLRYLPPNINCTSNSGLTAVHLASHAIERGGI
ELALIINISQVKSQDIWFLSTQSMLDTDLVQPFGVNSKGVIFAEGYSVLVLESDHHRLAR
QLVDGVSIKTAYKQINASRSNDVYWQSTCILKLVNQLLNDTRVKIEDVCAFIPHGNGTAF
SDSIEAKAIAILAGENMLPVLAYKGQIGYTATGSGLVDLIIGHHSVSCHELIKSVINEPI
INGIAHHFLIGPGVIKHHKSHLLKTGLGVDGSIIAVLLSNTAREAS
>A0A2P9FFG5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MA5143a|TrEMBL
MAGALSLDDGARVVALRSKAILALSGEGGMASVQLPVVEVEQFAPVTDGRVEVAAVNGPS
SVVVAGTPEGLDEVIVEAEARGARARRVEVDYASHSVQVEQLGEEIPAVLADISPTGASV
PFHSTVTAGRFDTAGLDAGYWYRNLRSTVRLESVIRGLVEAGHRLFVEVSAHPVLAGAVQ
ETAEAAGRDVAVTGTLRRDDGGLERLLLSLAEAYVHGAPVDWRVRFAPVGADPTPDSRVP
HVDLPTYAFQHRRYWPETTAVAAGKGRAVDDWRYRVVWRRGTLPDGEGPRLAGRWLLIAP
EASHMERDPGASPRADVPTTAEGRIAAALRAAGAEVTLAAQAAPGDYAGVIAVPRSLGDA
VTLLRDLRAADVTAPSWWLTEGAAPVVAGDVVSPEAAQLWGLGQVVGLEHPDRWGGLVDL
PADWTEDTGRRLAAVLAAGRDHRTGEGDDSRARAALGDTALQGAVGVEDQVAVRESGTYV
RRLVRALSGGRRPEQVWEPRGTVLVTGGTGGIGAHVARWLAAEGAEHLVLTSRRGRAAPG
AVDLGRELEARGTRVTFAACDVADRDALAAVLADIPQETPLTAVAHAAGVATFSDVLSID
GDELVSGTAAKVEGARHLDELTAGLDLDAFVLFSSGAAVWGSAGNGTYAAANAYLDGLAY
ERRARGLTATSVAWGGWAGGGMLQGSESVAGQLERMGLRQMQPELAIGVMSEAVGQGETA
LTVSDMDWERFAPVYALSRRRPLIEEIPEAARVLHGGDPADDTATADTNAAARLRESLAG
LTDLERRDSLLDLVREHAAAVLGHASPDALTPDRPFKDLGFDSLTATELRNRLNTATGLR
LPATLVFDHPTPTALAGLLHDELLGGAPDDPMDALRVQQELDRMEKALLPAVTAPDMDPG
TRADVAQRLRDLAARLSGTDPDAPPRTADGLEAATDDEIFDLIDRDLGVG
>A0A086M0F9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii RUB|TrEMBL
MTEAATPQNVTSPADLSKQNVSFRPGVNAVEFVSGYSHAGSVVCSLPSPIFFNKASSSNG
NCESNASTASSSAALGTEASSNVRTGTVLIFDCGSGNTWQHLRQWLSDEGASHIVVVHAC
AEEGADTLGVKTLHPSRVNGGQGCSQTLIKEVKCRPHHPEEVVELFKLLKEGLHFPLVRG
IFYILGEKLDSLLANQTTSSVHDMMKTASGAWSIHHALGQLGMEADLDFFIFFSSISALF
GSISQSISAAVHASLDALAYYRRHLGLAATSIQWAPWADGSSATSPQIVRHWLEKGGVSS
VRNPLAAVSAILKNHTAIGAVVACFHADPTIMHEMGETDQECTFLSSGPAANTRDSTSGN
VKVRTNPVKSRVFQNVSPSTDTCGENHKDELLVILTQLVRREVIEIASCYVFFEGNNLST
DESLVDLGLDSLSAVELRHTLQQRFCVNIEPTFLQANATIDSISALLVTHVATSLTGALP
VLPLSCPGLASAVDDCALVSLALRLPGRCDSLDAFWASLQSDSGYCRPGASEACDQCFMH
RAGSGELPAESQSIGTNLDARKGFCWLSNRDAFDSHFFGISFTEALATDPCHRLLLEATY
EALCKLNTEQQSGTSGTPIAVFATSSSTQMRASLPSYTKPASSQNTQDNNGCLAASFLSY
HLNLTGLAVPIDGSDSASLIALDLGREHLRGTDSVCQAVVVAAGSLLPICSHGWPSACTS
PTIRRFRGRDDHAFPDRETYAVPRGEGIVSVVLQRLSVARENGNSPMAILKGISLIRMGR
GERPIPSQWRTADVKLRRKTIVEALKMSRVEPRTVAVLETDGLTGSQAEDAYTVEAMADI
FGPRHLAESCSPLVIGNASLHIGQAREASGLATLAKLVLMLERGYAPPIPRLRRLHPDVK
RGILPSGFVMFPCKKMDLLAFRQHPDHVYGPNEKRDQKEGRPLIGCVSSLGSDKTSGCFI
VESSPRRHGRTSDTRVSLERAVPLAGTKDACSHNYLHVRSTDGSESEIRGDDRAVWLFCD
DLWGLQSVGRGLYCSDPAFAALLEQAERVLGNRIPQPLSCLLYPSTTAEFQKAEDALAFP
RIAAFVLFSLQWALATCLRHQEGEPTAVMGLGVGEIAAAAVAGILSLEDAVELLELLSSE
TRTCDYRNKPMPGGNVNSGGLFDRGNSGTGGCGVAQDCKSPWVLCGLNKTPTSESAALEF
SVLESRRGSSSRISSETPTSNTTPHNRDVFQERFSRKPRRATCPSPIIRHAWEKVAHGNP
ENDEEAELECPSSQSRRANCPSPAIQHACEETAHGNHANDGEADLLMDVFRFRPEPSEPL
GQVTARIALRNATCLFISTVSGRLATDTLIRAAEYWDPLVPKTQRVHRAVETAVQVAKTA
KLVCIGCSAQDGVHLSVGLPSVHPISPSPLRIFCFTGSSPSPQLLAPCESASGSSPRVAV
VEHHGADSNLGGGAPWWKHLLFRLPQLEGFPSGCSASTRLLADRLVADVPTPDNHMINNP
QTAAVQGAGETLGTLREGSSGEGEDGEKGYRSESVNTQHPVYKVYRRCSEPELHESELSL
LCSDTVCQPSLEKTVELFIGTGLEQQGKLSTVSSSWLVFSDIVAPSPISLYSTLAFQNED
GEQRFCTLNVASQVATVYAEKVKTQVCSIIIECKRGFKPPREIARCHFVKNQTAVGKHEP
AVSSLSRIRWLPATKLPEGWLRTRRPHVWPCKIKVTKAACPLPTRRVDLQEIYWGKRHIL
CRFRMPRNPPRDGVEKSTQLIAILARLVTVSVGVAATCVLHETETSGRYSHSHPGPQVED
DQKTHMDALWVCPYVPFSECWCVIRHRRNGSSIKEGKGRDWETCDVEIFSENGTAVAVVL
GFGIQSHALSMRMMEGRGNDGDSSVSTTVCVA
>A0A2P9FI09|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MA5143a|TrEMBL
MPDLLALPTLRKGRDETRSLATALGRLHVRSAGVDWAAFLAGSGARRVELPTYAFQRDAY
WLETVRDSAEEPRTGNGDLYTTAWQPVEGVAPAGARWAVLGQPDGRAGLLAKALALHAGN
TAFVRPDASTVDEAADCLVLPLEPAPRAESGADGHGGRGRGGPEAVRRLTHDTLARVQSV
LAEERSADFRVVVVSGGATTGDPAGAAAWGLLLSLQAEHPDRFLLVDLEDDGADAVALAS
AVATALARSETQVAVRGGELCVPRLVPADDPPADAPPADTLPVDTPTPAHGTVLVTGGTG
ELGGLVARRLAAGHGVRDLLLVSRRGAHAPGAEALAADLERDGARVTFAACDVSDRAALA
AVLAAVPADRPLTGVVHTAGVVDDGVVTALTPERVDTVLGPKSDAAHHLHELTRDADLSH
FVLFSSAVGTLGGAGQANYAAANACLDALARDRRAQGLPATSLAWGLWGTGGGMGGRLAE
VDLRRLARAGVLPLDAERGLALFDRAWAADEAVLVPLRTDPAVLRERATAGTLPAALRTL
VTNTGRETPGRARPQEPGGAYANGTSANGAPSGAVQAERLAALPPAERARTLLDLVRARA
AAVLDYPSPDSLDPRRSFREAGFDSLTAVELRNSLAAATGLPLPAALVFDHPSPAALAEQ
LERRLLDQAGPAHTRQRPELPALLDQLEAALAELPADDPERPRAAARLRALAGVGTAPQT
GGTDVEERLAVASDDELLDFIRSELGKE
>A0A7D4AW34|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinomadura verrucosospora|TrEMBL
MAPPGRWTRFALPASAPRVRLICLPCAGGGATAYRSWVRELAGAGVDVWPVQLPGRENRF
EEDLPGSMEDLVEELLDQLGPALRAAPYALFGHSMGASIALALAFGARARGLPAPVRLFP
SAGRPPNRPDPDPPAHSLPKAAFAERLRAYDAGSFLLREPELLEMFLPKLRGDFALFENY
RPPDEEPLDCPFTVLGGLDDASVPAALLPAWADYTRGAFEVRLVAGGHLFLDSARDAVVR
LVRGRLVPEAAG
>A0A1X2E7H7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacter terrae|TrEMBL
MPDRCEDPVVIVGLGVEAPGGIDTAEQYWSLLADGREALSAIPEDRDWAVRELIDGSHRD
GFKPICNVGGFLSGAAEFDPGFFGIAPREAIAMDPQQRVALRVAWRACEDAGINPDELTG
HDVGVYLGASVTGYGPDMAQFSAHSGHLLPGTALSVISGRVAYTLGLAGPALTVDTSCSS
ALSALHLAIQAIRTGDADMALAGGVCVMGSPGFFVEFSKQHALSDDGHCRPYSAAATGTV
WAEGAGIFVLQRKSAAVRDRRHIYGEVLSSRLNQDGHTTGLLTPSGQAQQRLFRHALADA
DVHPGQVGMIEGHGTGTRVGDPVELRSLINVYGADTEPGAGPRLGSVKSNIGHTQAAAGA
LGLAKVLLAAEHQMIPPTLHVRDGWHDGIDWDGGDGGGITLAETITAWPARDGHRIGSVS
AFGMSGTNAHVIVAVDDAEMAPSC
>A0A447GGQ9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium basiliense|TrEMBL
MTATNYRLPDGNIPVLLTSDTAELVPGEAAALLSYAADHPDIDAQAIASMLFRTRMPRKH
RALAMVANRDELLSALRAVTDGREHPAVVRTTAPATTRRLAYVFPGQGGQRPGMGRLFYE
SVPAFRAEVDRCTEAFEAHLGQSPLAYLLDEHHPAEDNASTVQPALFTQMAGLAAMWRSF
GIAPDITVGHSQGEIAAAYFSGKVTLADAVRVVGIRAGAADEFAAGDYAMAVIAADRDVC
EDVLARCSGWAQLSVVNSPNMVGISGERQTVEAVVNAFTQRDVFARVIRVQFPAHTSLIN
QLGDNVRATAQRELQNPKFLDTDIECLGATLGDAITQELPVDEYWFWNLRNTVRFDKAVA
AAATLGVDTFVELAEHPTLQLAIQENLAAGLSEDDDRTTTVVGTSNRTATSLGEFTHNLA
QLALHDLNYSWGCLRIDTEGRPWLPLPDFPNSLTNDSRLWLPYAEVPTQGTGRTSTSTAG
PAETAAPAHETVAPPRLLVEKWIRLSRRSLVRPRSIGLVDHTGAYAELVTDLSEAARELG
ATATLVTDNIDSSTDLNALVILLARSPRLDDGAAAAAVTTFFSDRAWWPGANKTINDCWL
VTVGGEAVLNDDAPPDPVHAAAIAGLRSIGSEYPGVNFRHLDLPTAPMSSDAAATILSAL
HTDGESALAMRDGGLYAKRVVEIDADTPDSGSAPQHVLVIGGTGTLGLDFTEHFARRGAR
RITIVSRSGETATVAERLQHIRATTSTHIHVAACDVGDQAAVSLLARSNQDDPADLIIHA
AVQYSGIELADITAEKVDQALRAKVVGIWRILQTFPRTADCRIILCSSVAATVGGRGLII
YAASNRMLDAMAHRLRADGVDCVAVQWGQWQVSSDPGNTGMAKLAFTGLLPMTAADALAL
GMSRLPGNAIIAAFDLDRARSVLETCGHAQLLSQLSAPLAEVTPSAQSQNTIGPAGLSHR
LVNLLAGAIGVDRAETIDTTVPMVAIGLDSLQALELRRRVKNEFDHDLDVAELLGGASIA
DVVGMLGASTQGR
>A0A086QUJ4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii MAS|TrEMBL
MANAEKLVKLHGLWFRSLWKWAEKIPHEDAVIWLDENGSKAASLTYQKLRREALIIATCL
RQVHCQPGDRAILCYPPSVSFVPAFLGCQICGLTAVPVYPPGSNDRDSDSIQRIVAMVKT
TRPSVVLSSSPLRYFLKEVFPGAAARCVSDIRWIFTDELPDHVEAGSAFELDSLDIKSET
PAFIQFSSGSTGNPKGCVVTHMALLHNIHLNWRMCGAFHPGTEESLYDLPVESYAEFTEK
YQKHLVATWGHRLRSFSWLPVTHDMGLVGMLCVPLFFGCTAFFMSPIDFVRAPHSWLGGM
SKFGCSFTAAPDFAYALAARKVPDDLVLELNFEKILACVNGAEPIRPATIEAFLKKFSPA
GFQPWMMSPAYGLAEHTVGVTGRGSEGRKPMSPKIIEVNNEKVAQGDTVELFKRSGKQEN
EMCTKLIVGCGIPHEDVIVKIVDPRLLQELSEWQVGEVWVSSPSAASGYFGSPVETASTF
NLHLNTADGATRGDRTFLRTGDLGFLGDGELFITGRLKDVVILRGCNYYPQDIEEAVERC
DSVRKGGVMAFSISTTDDAEGLGVAAEIQKGSEKPAKLKLIYADIVRTVNKVLHLPLQRL
WLLRAGSLPKTTSGKPRRSEARRRLLQAERCDDILYSYTRNLSHSGHLPFRPGTFELDME
QKQEDSASTSKSEVNKSLVESLSTAKGARHTDDGFIFTNGQQNLHEAKKDQHGTSDSTLA
EPVSNAILDPITRVTDALLVTADGTSVHKDEEELSLVAECFACVTGVEKSCLRPDTPFLS
LGLDSLTAVELANEIQRRMKQPVEPFELFEFADLRSLALYLRNKKLDHGKDARGRQTKSS
PERSLGIVQVQRPSVFVTGVACALPGSCQTPDKLWEILDAGIDCVGPIPPNRNFCASQNF
AVIGEPRTANASFCVTEGGFLDDVDLFDNSFFGIPDAEAMTMDPQQRLLLMKAVEALHAA
GMATIDSRSAPIATFVGCCSTDWQRMNLGEQIQSFSATSHSASMLSNRLSYTLGLTGASI
TVDTACSSSLTALHCAMQELQHRHVPCHTAVVATVNLLLTTDVTLAFARAGFLSPTYRCK
TFDDAADGFVRSEGVVVFVLQTDVSETPTPSFKNQQEDNEGGQGECGTRIPASGYLCRIL
ASTVVHGGKTGSVTAPSGSSQELLYKQTFACAQVPPRAVDLVETHGTGTRLGDPIEISAL
CNSFAPDMETRKHRLVLGALKTNLGHLEGASGLAGLLKSVLCLNRQRVPPNLHLRKLNRF
IDFRSLPVLLPTKTVPLPASSSETKDAVALVTSLGFGGTYAQVAVQVPSTTGNEMLLRNQ
EPVQWNKKCFDVGKLVSQSNSFQSAVSHNDTKGPCFWEVGWEFLLEFDSITLTLPTLPEQ
APPAKWLVLTSPKAQQSFRKFSVNIFLPGIRMTFACLEELKAPEHLEAILKAETWTAIVS
TYTTETGSCMTDSSDLIGITLQILQTYGQMASQSAVLPRILFLTQGCFQVGAAASLLRAS
PYNAGIIGFVRACRLEIESLSGRKAPIYLIDFAANGTLTETLSAVSKLLGMIDIRNVDET
EFAICGKRVFAPRLLPLHLGLEEILPAYDHYMDLTKKADESPAGTAKFPRLVEPANKACR
VRLLALCLDEIFPIEAISPASKAFELGESRPCTLPYGYRNRRQKAFLYQMERAFV
>G8SM53|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)|TrEMBL
MDQQEIRQLMATQLEKSRRLQARIGELEAASRAPVAVVGMGLRLPGGVTTPEDYWDLLHR
PGDASREIPADRPGLRAVYDPVPGRAGRSYVDRAGFLDDVADFDAEFFGISQREAARLDP
QQRMLLETAWEALERAGVAVRRADRLDVGVYLGMMASEYNERFADRGDAGRVDPYYTTGG
GLCFGAGRISYVMGFKGPVISVDTACSSSLSALHLAVRALRSGECRYALVCGSNLLLSAN
LMVSLSQARALSPGGRSRSFLAGADGYGRGEGVGVLVLQRLADAERERRPVLAVVRGTAM
NSDGAASGLTAPNGPAQQEVVRAALRDAGIDPAELGWVEAHGTGTALGDPIEVHALAEVL
GESIRRRGVPLAIGSVKARLGHLEAASGIAAVMKTALMLRHGEIPAALDPEDGPLNEHID
WAGLPFTVPRDHQPWPAVPGGRVASVNSFGMSGTNVHAVLAAAPPVPDGDPVPPEQPHLL
TLSARSMPALTALARAVASRLGKAAPAEIASICHTLRCGRTAFPYRLAVVASTGPDLAVR
IEEALRRPIAAAPRGGPGPLRLRSGDAGAPPLLHRLGVRTVPEPGTGPARLAWGDRRYPL
TTPELTLTAVAALFEDGADLRFDALRGPHDRFVDDLPTYPFQRRRCWVDEPVPDGPAVTA
APERADGAVPDAADRTAVHDYLAARLREVLDADELDEQRSFLDSGGDSFASVLFVQRVEE
AYEVGVRPEDLPLDLPLAEFLGRLAAGVTRRTGTAS
>A0A0C5Q128|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pelosinus fermentans JBW45|TrEMBL
MQKQLEILYEQIKEQKISPENAIKEINELKLQHSLKTQVSETVLMEGDAIVAAVAPDLLQ
EKVVHYFKKLLSTVIGLPVHRIEADVPMEEYGIDSVMVMQLTNQLEKIFGSLPKTLFFEY
QTIQALIEYFLEVYQDQLMGLLGIEEIAATATRKSAKDSAAMTGSVKPVISNRRHLRFTT
PYSDTPQEKVRATDIAIIGLSGRYPQAKNIQEFWKNLQAGKDSITEIPKDRWDYNLYFDE
DKSKPGKTYSKWGGFLNGVDQFDPLFFNISPREAEIIDPQERLFLQCVYETLEDAGYTRE
ALGMHQGGGLGGDVGVFVGVMYEEYQLYGAQEQVQGRPIALAGNSASIANRVSYFCNFHG
PSVTLDTMCSSSLTAIHLACQSLKQGGCEFAIAGGVNISIHPNKYLALGQGKFVSSKGRC
ESFGQGGDGYVPGEGVGAILLKPLSKAIAEGDHIYGIIKGTAINHGGKTNGFTVPNPNAQ
ASVIGKAFKEAGINPRTISYIEAHGTGTSLGDPIEIAGLKKTFQEYTKDKQFCSIGSAKS
NIGHCESAAGIAGVTKILLQLKYGQLVPSLHSEILNPNIDFGKTPFVVQQELAEWKRPVL
EINGEIQEYPRIAGISSFGAGGSNAHVVIEEYMDKDEQPSSIRITKQNPAIIVLSAKNEQ
RLKEQVQQMVAAIQEQQISDENLANMAYTLQVGREAMEERVAVLVGSSKELEEKLKGFLA
DQDGIEDLYRGQVKRNKDTMAIFAADDEMQEILKKWIAHRKYGKLLDLWVKGMIYDWQKL
YNDSKPRRISLPTYPFAKERYWVPEAGIAASSNIISPVTAGLLHPLLHQNTSDFSEQRFS
STFTGQEFFLADHVVKGQRVLPGVAYLEMARAAVEQAAGVLAEDKIGIRLKNVVWVRPVA
ALGQPVQVHIGLYPEENGEIAYEIYSDSETVDREPIIHSQGSAVLRSVTETPRVDLKSLQ
AECGQSTFTSSQCYEAFRTMGLAYGSSHQGIEVVYTGQEQVLAKLRLPASVSNTHNQFTL
HPSLMDAALQATIGFMLVTGVTGSEASLKPVLPFALQELEILSNCPSVMWALLRYSAGSR
AGDKVQKFDIDLCDEQGNVCVRIKGFSLRVLEREVGSVGKIGNNEMLLLEPYWKEQASIL
ETMDSAYVQHVVMLCELSEAYRESVETCMDTIRCVTLQIEKESIEERFQAYAVQVFEEIQ
TILKNKQKGKVLIQVVVPTQEERQLFSGLLGLLKTAQLENPKIIGQMIEVEVEGLSQEII
EILKENSQSSIDNHVRYQGGTRWVNGWREVAVTEEISLPWKDNGVYLITGGAGGLGLIFA
QEIAHTVKNATLILTGRSVLDEGKQEKIKAIETLGAFVEYRKVDVADKQAVGDLIQSIQE
KFGSLSGIIHSAGVIRDKFMIQKTKEEMQEVLTPKVTGLVNLDHASKEMNLDFFLLFSSM
AGSLGNVGQADYSTANAFMDGYARYRNDMVVSKQRYGQTLSINWPLWKDGGMHVDKEAEK
AMQGMGMIAMETPIGIQALYQGLVACKDQVMVIEGDVARIKQKLLSVTAATAVQVEKASI
LAFPAAGIDTRDLLEKVQATLVQEVSKILKVKIEDIDVGTELNEYGFDSITLTQFANELN
QKYKLELTPTIFFEYPTIHSFAEYLNEEYKEVFTSQFAVQPRVEILLPTMGDEVTEISST
KKRHSRYVKMVDLSIAKSVASTYEPIAIVGVSGKFPKAKDINEFWRNLVEDKDCITEIPK
ERWDWREYYGDPAEKANKTNIKWGGFIDGIDQFDPLFFGISPKEAEFMDPQQRLLMTYIW
KAIEDAGYSAQSFSGTKTAIFVGTGSSGYDKLLSKANIAMESYSSTGLLPSVGPNRMSYF
LNIHGPSEPIETACSSSLVAIHRAVSAIESGNCQMAIAGGINTIITPENHIKFNKTGMLC
EDGRCKTFSNQANGYVRGEGVGMLILKKLKAAEEAGDHIYGIIRGTAVNHGGRANSLTAP
NPKAQAELLQTAYTKSGIDPRTVSYIEAHGTGTELGDPIEINGLKTAFKELYKETGDPQV
LNCHCGLGSVKTNIGHLELAAGIAGVIKVLLQLKNKTLVKSLHSETINPYIQLKDSPFYI
VQETKEWKPLHDLQGNVIPRRAGVSSFGFGGVNGHVVIEEYIPRDRQMPINMDSASKPVI
IVLSAKSEKQLKEQAQQLLDSINSQQLSDENLTDMAYTLQVGREGMEERVAVIVRSIKEL
EEKLRGFVEGQNGIDEFYRGQVKRNKDTMAVFTADEDMAKTVEAWISKKKYAKIMELWVK
GLIIDWNKLYGDSKPCRISLPAYPFTRERYWVPETSTMDKLTSSAGVNLIHPLLHQNTSD
LSEQRFSSTFTGQEFFLADHIVKGQRVLPGVVYLEMARAAVEQAAGALKDDRTVIQLKNV
VWARPLAVGDQSLQIHIGLYLEASGEIAYEIYSQSEQADTKPVVHSQGSALLSSATGNLT
LNLKALQDECNQSTLTSSQCYEIFGAMGIEYGSGHQGIEVVYVASNQVLAKLSLPSSISD
TQAQFVLHPSLMDSVLQVSMAFMMVSGDAGGKASLKPVFPYALQELQIVSNCPSLMWALL
RYSVDSRADDKVRKLDIDLCDEQGNVCIQMKGFSLRELGGELGLVGATASINRKGGR
>I9DAF9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pelosinus fermentans JBW45|TrEMBL
MDKQFNTIMDCNNQIIKNHLVYGEFLLPGLAYIDILFQIAQSNGFDVHKTVLKNISIFNP
LVVREDLSIDLTISFKEHNGYCKILVEGIGKGINGEIVQAHKKYMSAELHPNDGVSFDQT
IDIEDIKRRAAHIVNIEEAYTQARKNGLVHQDIIKANGNAYLTDEGGLFNLAVPTNYIED
AKDYIFHPTLLDSSTMVATMVLKSLLSGKSDQHVEILYIPIFYEAFFAAELLQAQCYVRV
LASSVSVIKDIVYLDIEFFDEKGKQIGILKRLTLKQIRSKDTLISPQATVSNMPKHDVPS
VSVTPSLNDQTISNETLKTILTNIFGKYLKMKPHQINLQLGFFELGLESAELLEVITELE
TILDKTLNPTLLFECNNIEELITYFEQEEFDQANTNKSMTDTFIGSKKVVSESNQESLNK
CQETDIAIIALEGRYPEARNIQEFWGNLQDGKDCIVEIPKERWDYSLYFDEDRNKLGKTC
SKWGGFIDDVDKFDPLFFNVVPKYAGIMDPQERLFLECAWNLFESIGYTKETLQRLYQGR
VGVYVGAMYMQHHFFDADVATESALTISSYGSIANRVSYYFNLQGPSVAVDTMCSSSATA
IHMACESIIRGECQAAIAGGVNVSIHPKKYVGLSQVQLLGSHLNCRSFGDGDGYIPGEGV
GAVLLKPLSKAIQDKDSIIAVIKSTITNHGGRGNAYAVPNGNAQARLIEDNFKKSGIDPR
TISYVEAAANGSALGDPIEFNALTRVFKKYTSDQQFCAIGSVKSNIGHVEAASGIAQLTK
VILQLQHRQLVPSIKADPLNPNINFNNTPFYLQRELQEWKRPILMINGEECEFPRRATTC
AFGAGGSNAHLIIEEYIPNQEEPVDDRFIETPQIMIFSAKNQERLLAVAEQMLICFERQK
ELNLADVAYTLQVGREAMDSRLAIVVSNQEELVNVLKEFLKSAKENKEIDDFIPLFTWDL
GEADSPIRSFLSGGLGESVVQVLLAERNLEKLAIYWTQGGNIPWEVLYNGQTVRKIYLPN
YPFARERYWILTSEVTNHQSTITELFEEEEFKFTIDPHKSTQENIQDYSMQMLAKKLCIA
QDQIKLNKNIYDYGMDSIVIMKFMHEFEKQFEIKVTFRDVVEYETLASLSTYLAQKVDSQ
KNQNKQAVNSKLEEEQQKMGETIDEQVVGALEKLVQGELRLTEVRKLIEGGGKI
>D7DX34|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc azollae (strain 0708)|TrEMBL
MAASNLEAALSQLQIEVSNCEKALFQMISERSNMSKNTNVINQINQQSQQTNIAIIGMAS
IFPKSKNLQEYWENIIQKVDCITDVPPSRWSIEDYYDPDPKAPDKTYCKRGGFIPDIDFN
PMEFGLPPNILEVTDISQLLGLLVAKEAMEDAGYSESRQFNRERTGVILGVAIGRQLAVP
LGARLQYPIWEKVLKNSGLSEVDTQKVIDKVKSAYVQWDENAFPGMLANVISGRIANRLD
LGGINCVVDAACASSLGALKMAISELVEHRADMMITGGVDTDNSIFAYMCFSKTPAVSPG
DKVKPFDVDSDGMMLGEGVGMLVIKRLEDAVRDSDRIYAVIKGIGSSSDGKYKSIYAPHS
EGQIKALRRAYENAGYSPETVGLIEAHGTGTMVGDPTEFTSIKEVFGENNSQTQHIALGT
VKSQIGHTKAAAGAASLIKTALALHHKVLPPTMNITKPHPKLNIESSPFYLNTETRPWIS
NRPRRAGVSAFGFGGTNYHVVLEEYENEHHHSYRLHNTAKSVLLFASTTQELLSRCEDIQ
RQLTSPEKEIHYQQIIRGSQSLKIPVNCVRIGFVTDSLTQAEEFLQISINQLRNKPEAES
WEHPKGIYYRQKGIETTGKIVALFSGQGSQYLEMGREVVLNFPCLRETYIYMDKLLCEDG
LKPLSEVVFPQPVFDQSQKQNQLETLQKTEYAQPGIGVFSAGLYKILQQAGFKADFVAGH
SFGELTALWAGGVLSEEDYFFLVRERGKAMATPAESDAGGMLAVKGDINQLKELIKDFPQ
VAIANWNSQRQVVLAGKTAEITKVQNVLKEKGFSTFLLEVSAAFHTPLVSHAQKPFAQAI
EKVTFNSAKIPVYTNLTGGFYPNEAPAIQKNLKEHLLNQVLFQQEVENIYKAGGYCFVEF
GPKNVLTNLVKEILGDKPHIAVALNRNSTQNSDLGLREAVIQLRVAGVALQNIDPYQIET
KIPEVNQKKVLNVPLNSTNITHKAQRAFAKALENGHRISANSPQLEPQPAVAETTITLPR
IREDLEEEYSYGTDVNDVNHRNNSNLEKVAIQLPNYARVIDSLEHSLAEFTRQQRDIIHV
HEQYLQNQTEYTKTFYELMQQQYKLLENGDINEYQAQTQQLAISSCERNMMRFHDHQADT
LRIHEIYLNYQQDYANNYFQLLHKHYNFLFVTDDISVPQHHLVEETNGKTSVNRSGANIS
PSFAGEGLGEKLIFPPQQEEQLEENSNTITVIPTIPINIDTSTLGETLLSIVSDKTGYPV
EMLDLSMDIEADLGIDSIKRVEILGELLELYPDLPKPNPEELGQLRTLGQIAEYIKTLVL
DLLSQKVEVSGATTFPVQMLVAVPHQDVADEPQILESHPNVADTENLISSGEDDVKQSTG
DQITQIVEKAPAIRIPADLSNVLLTIVSDKTGYPAEMLELSMDIEADLGIDSIKRVEILG
GLLELYPDLPRPNPEELAELRTLGQIVEYMQHQAQGVTKLLTNEKEEFTSTELHPQILRS
PATLKLLSQPDALDFIIPETDVILITDDGYSTTEELATSLIAKGVKPVVLSFPNIQSNLP
AEINRVILTDWNEKTLQQQLSNIADDFGAVATFIHLNPVFSGSNEIEILILRHVFLIAKH
LKTSLNEAATKSRSCFLCIARLDGEFGLGNTTNFSPISAGLFGLTKSLNQEWESVFCRSL
DLSPDLDPQTSVKHILAEIHDPNLLVTEVGYSSKGRFTLVAEPSSLSLQSPIINPQSQVF
LVSGGAKGITAQCVIKLAQQYQCTFILLGRSSRETEPVWAEDCENEAELKKRIMEYFQAQ
GEKPTPIMIQKKYHDISSQREIQNTLKAIAAAGGKAEYVSVDVTESIVLAEKIAPVVEYL
GAITGIIHGAGNLADKRIEEKTIQDFETVYAAKVKGLENLLNCVPPSQLKYLILFSSVVG
FYGNIGQSDYAIANEILNKSAHLIKHNYPHCHVVAINWGPWQSGMVSPELKKAFAERGIE
TIPLETGTQMLVEELINTYQENVQIVIGSPLVYIPTTLSSDLKTYRLKRQLTLKSNPFLH
DHIIASRPVLPATCGLLWMANACEQIHPGFKAFSCNNFKVLKGIVFDENLSSEYTLAIQD
IAKIENKEIELAAKISSINPEGKIRYHFSANVILKRQIDTALNYELLNLTLDEQFLITNQ
LLYQNRGGSLFHGITFQGVKSVLNASPGKLTIKCKLPQPTAQKQGQFPVQTFNPYIADVQ
IHALWLWIQHFHKVGCLPSEIQTFEQFAPVPFDETFYVTCEVKSKTESQVIADIITHNRQ
GKIYNRMIGAKGTILTKQIG
>A0A0L6JGG9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933|TrEMBL
MLDFSMFKLTEDYSGQDKIEIKEVSAKEIAIIGVALKFPGAENTDEFWKLLENAEDCIRS
IPEKRRKDTDAFLKAVQMEQKNAEYFQCAYLDEIDKFDYSFFRISPREASLMSPNQRLFL
ETAWKSIEDAGYGGNKLRGTKTGVYVGFGSDSPYDYKNYVAQMEPSFASEAVTGNLSPVI
ASRISYLLDLRGPSMSIDTACSSALVAVHTACMALRNGECDMAIAGSIRVNFLPVKGQFD
LGVNSSDGRARTFDESSDGTGSGEGVAAVMLKPLNKAFRDGDNIYAVIKGSAINQDGSSI
GITAPNVLAQEDVIIAAWRDAGIEPDTVSYIEAHGTGTKLGDPIEIDGIRRAFARYTDKK
QFCAIGSVKTNMGHLDNAAGMAGLLKAVEALRRKKIPPSLHFNKPNRRIPFEMSPVYVND
RLNEWETDGFPRRCGVSSFGFSGTNCHMILEEAPEPGKKTPQKSFDVHLWTLSAKSEEGL
KALICQYKLNLDGDLDIDLADICFTANTGRGHYNYRLAVICRDLKELKNTVSRLDITNMD
EALPTNVYFGEHRLVSQDKAKIKRVEITDSEIKQLNEKASRKIKELKKGTFESCCILDEI
SRLYIAGADIDWEEMYRNMEVKRVSLPSYCFERNRCWVGVPDKCSNRGSGNIKDLLGFED
IPHNLKNEIEEQIKKWKMQLAVSLPSDSIMLPKIVEIKGRDTEIYTDSEKRIAEIWGEVL
GFQELNIHDNFYELGGDSILAAKIVNRINSRIGTEISVADLLISQTVAELAVNLDIKHTA
QDNGNQLYSIADKRDFKEYFAISPSQKRIYILQKMDEGSTIYNLPVFLSIEGNMDIECLE
TAIRELVGRHESLRTFFELKEGNIYQKVSTTVEVQVEWPPFDGKNLNDTLQKFIRPFDLS
KAPLFRVGIIRLSEKEYIFMFDMHHIISDATSLDILVSELIRLYKGYILPELKIQYKDFA
EWQLQFIDSGTVQKQKEYWLNLYRGDLPVLTIPTDFLRPAVQTFEGDKLHLTVSKELGAD
IIKYASANGVTLFMLLLAAYSILLSRYSGQEDIIVGTPVAGRNKADVENIIGVFLNTLAV
RNYPCGEKTFEEFLVEVRDNTLKAFANQDYPFEELVESVAAKRDLSRNPLFDTMLILQNT
GKIKFDIDGLKVKAYEHTHMVSKFDITVEAIEIHGSIRFSVEYNTRLFKKDTIQRFLDHY
VNILKEVVMNPGLKLCEIEMLCSEEKNQILFEFNDTKRHYPKNTTIDKLFTEQVNRTPES
IALVFGKKKMTYREMEDRANSLARTLRERGIGRDDIVGIMAERSLTMMIGIFGVLKAGGA
YLPIDPQYPKERIGYMLEDSNAKMLLTMGHLMEQVQFKGLMLDLESEDVYSPDRSAIQAE
NTSEDLAYVIYTSGSTGKPKGVMIEHREVLNFIYGVAEKIEFSSDKTILALTTISFDIFV
LETLLPLTRGLKVVIADENQQRNSALLNDLIESKNVDMLQITPSRLQLLMTGGVELTCFQ
SLKEIMVGGEPFPKKLLGDLRKMTNANIYNMYGPTETTVWSTIKKFELEEDINIGKPIAN
TQVYILDKYLRQQPVGVAGELFIAGYGLARGYLNRMDLTKEKFVCNPFDEGRRMYRTGDL
ARWLSDGNIECMGRNDHQVKVRGYRIELGEIEEVLLRYPGIEGCTVEVRESSEGNNILVG
YYISQGNIPVSKLMNYLAMELPDYMVPGIYVHMDKFPMTPNGKVDRKALPEPDASRPELE
TQFVAAGTETEKVLSDIWREVLKKDLVGVRDNFFELGGNSLLLVQMNAAINERYPGKVDV
ADIFSHPTIEKLAQMIEKEKAFDINCLNLGFMPFPPEFFSERKGIGEESVLRFKIEEPVY
RAMETVTAKRELEFEDILLGAYIYLLSEVSGEQLVHVNTVCDNKGYLNTITVNMNDARNL
WTFFQDVHSHIEELRHKVGFTVEEVTRVQVDRKENSIIPLFITKYNNSGSMDNFDMVLKM
DSGSGAIDIVCEYNGSRIGNEKVKEFILNYSRLVEMMVSQMEQIAFQQL
>A0A117EFU6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces scabiei|TrEMBL
MERSNEHVNDGAASTLLDVLLGAARETPGRTVVHVRGDGREHTVTFADLRDDALRVAGGL
RAAGVTPGTPLPLVADRGDAFQPMFWGALAAGAVPVPLAPEPRRIGPVWELLGRPPVVVD
ETTAAVVAATGDESEAPGAQLPLPIRMLRLDTLRRGRPPRHLPRPAPGDVAFLQFSSGST
GAPKGVELTHAGVLANIRQIRAAMAIGPDDVLATWMPYFHDMGLIGTHLVPMAARLKQIR
IEPLSFAKRPALWFEAVDRHRATLLSAANFALALAVRRVPATALDGLDLGCVRLLLVGAE
PIAPRVWREFTALTAPAGLDPRAPLPVYGLAEATLAVTVPPLGERAQPLVLDRAALARGR
VTETEPGPDAVELMDLGRPVAGCEIRITGASGSPLGELRVGHVEVRGPQLGRGYHRAPEA
SAEAFGDDGWLRTGDLGFLRDGRLCVTGRHKDVVFVNGRTFHASDLEETVAATPGLPPGA
VAVVGSTDPAGGGERAVAFVQWARPAPSAAAPVLRAAAARLRQTLGHDDVRVLPLPPGAF
ARTTSGKLRRGVLRTRYEAGAYTEVEARWTEAAGDTAHPAARPATAGRGRTGATSRTDGP
AAGVPRSPREVREAVREVWARALEMPVSAVGPHERFFDLGGSSLRAMTVLAGLEDVFGVT
VEPGALREHDTVAGLSGHVLRLLEEEGAKGLPTGGREPSGEAAPGTPGAPGTSGTPGTPG
TPGTPGAPGAGPAGAVAVLSVACRFPGAGTPEAFWDLLASGGDTVGGLPGGRPGDGPRTG
SFLTEPAAFDAGFFGMDDAEARATDPQARIFLELAHEALERAGYAGPRRAARRIGVFAAT
GDSGYREMLAEAADGDLARHPAALTGNLPNLIAARVSQVLDLNGPALAVDTACSSALVAL
HLARRSLLAGECDLAVVGGVNLGLTPTGHRLLEATGALSPSGRCRAFAADADGFVPGEGG
ATLVLARPADARAAGDPVLALVRGTAVNNDGRSLGLLAPAPRGQREVIGRAYEECGADPA
DVSYVEAHGTGTPIGDPVEARSLGQAFPPRADGVPRGLGSVKANLGHLLNAAGMPALVKV
VLALSHRRLPPSPHSTPPAPFLADAAPGFRLVTGDAGGAEEWTGPGSAEGRPLLAGVNSF
GFGGTNAHAVLEEAPGQVADAVSAGAGEGPRLLTLSARSAGGLRAAAAELAAYLRAHPGV
DEGEVCRSVNTARDEGPYRLAVVTEGGDLAERLEAAGEPGTADTAGMAGTAGAARPRTVF
VLPGQGAQQVGLGRELYRTAPVFRDILDEVSSLTGPVLGRSPAAWCLDEDADPADLARTE
VAQPLLVAFGVALAGQLAAWGVTPDAVVGHSVGEITAACVAGALSPAEAVGFAAERGRLM
GRLSAPGAMAAVRGDEETVAAVLAESDGALCVAAVNSPTQVVLSGAVDAVDRAVAVLTAR
GVAARRLRVSHAFHSPLLTPVLDPLHNAAKALTVHRAGVPLLSTVTGHWNPDLTPGSGTE
TGSDSDSDSATGSGYWREHAIRPVRFGDAVGRLLDEGYDTFVELGAGATLGAPVRATAAG
RPGVTPSDVTVLTALPATAGAGASALLETAGRLWTRGAPLDPSAPASPARRTARRVPVPT
YPFQRGRYWPQRLVTPPAGPGTAASGTATPATEPLVRPLLWRDAPLGTAPGPTPRVRLTG
ADTPLRRALTARLAARGALVPRSAEGEGTATAPDTAAAPETVLWFAAAEGAADGAGTAVP
ALRETLSSLGTGPARLLLITENAYPTGDTDTSADTGTGTASGTHRCPGPRPAQALLHGFA
LALPEEHRGLSALGVDLCAGDPIDARLAALEEELSATATPGAGGTVARHAGRRLARTAVA
PAAPASPAPLPPDGTYLITGGAGGLGSALARDLAERGTPTLVLTGRTTAPPHALLTDLHA
LGADARYQAADITDAAAVDALVAGLPSLDAVFHAAGTARPGSLRGKPDDEIEAVLAAKVR
GTALLAGALRRHGREDAVCVVLSSVSAVLPGLAGALGDYAAANSFLDAFAGAERAAGRPW
QSVALGPVADTGLASGPPPHAGLPHHGPAPMTVRAALAGLRSAVALDAAHVLVAAPAPDG
GHEPSRGAGNRATGHHEPSAADDRPLPNPHAPTSTGINTGTPATSAVAALVRRLLAEALH
RPPQEIGDDAQFLTLGLDSLTAVDLARRLERELGRPLPATLLFEHRTLGELAAHLAATPP
PHTPASPPPHDPASGPAPSPGPYAPHPLTPLQLAFHTTETLHEGITAYGYLRQSVRGPLD
PALLGRAFAVLAARHPMLRLRFTGGDGPVPRQYAAPAGPVDTAPGWFEVRETPDLRRLEH
DLCNRPFDLTAQDPVRAVLVPDRADAHLAHLLLVVHHAAADGYSLKLLAEELWSLHAALA
RGDDLSRLPLPQARFADYTAAVDAERRSPAYAEDRRYWRDRLAAHTVPSPALPYDGDPEA
PPAPPLTHHRTGIDEELTAALRGTAARHGVSLFHLLLAVYGRCLARWSGRRAVAVNVARA
RRELPVPGIDTLVGPLADTLPVFVDVDPDEPVTALADRLRRIWAEAEAHATPASTDLARL
LSGLRPATGPAPRTAAEAGFSFARFPVVHGADWPVTVTPTAAATASAATRLGLLCWEADA
ALCLSWNHPARLFRPETVRRLADEYVAELRAAVTGPATAPATLTGPAIAPAVVAGDGLVD
RLRARFRATPLSVAVDAGDGTTLTYAALDAASAALAARLRVHGVRPGDLVGLLIEPGGTD
TVTAVVGILRAGAGWVPLDATHPSARHRDQLSRTGVRVLVHDRAARETAAALDGVTAVPV
MAEVPEVPETSPPGTTAPAADTPALAPSLSPSPSPEDIAYVIFTSGSTGRPKAVPITHRS
MTNYLDWSLATFGYGPGDRLAQTASVCFDASVRQLLAPLLAGATVHTLARDLLRDPEALL
DRVVADRITVWSSVPTLWERLLTAAEDRLRRDGTAPDLSALRWVHVGGEALPAAHVRRWF
DLLGTPDGDAPRPAHAHRIANLYGPTEATVNATCHLIDTRPGDDVRHLPIGRPVAGTELA
VIGEDGHESAPGEPGELLIAGIGLTPGYLGDPGLTAAAFTERDGRRWYRSGDRVRRRADG
VLEFLGRLDDQVKVRGHRVELGEVEAALLTHPGTARAAVLLRDGRLEAYVEPRTGTSPLD
PREVRAYLSRTLPPYMLPARVHSLPALPLTGTGKIDRNRLAPRDAAAAELPRTRTELPPA
APTAPWTPTERLLARTWSALLDVPESLISRQDDFFALGGDSLTVLELFSRLRRERPALPR
PTTVYTHRTLTALAAALDATAPDATTPGVRTPDVPQDRRPAHDLTPYPLTPSQQGFLLAD
TLTSGTPDADPAWLARFRIRGPLDPDLLQRCVDVLVDRHPMLRTVFPAGARPPVQQELPS
SLRLPVQKETLAHPGLLEERAAEEARRRFETWAWPLVRLRLLTVAPDDHVLLVHAHHLIG
DGYSAALLTRELLTVYDRFARGLPHGLEPLESTFRDHVLHRTAPRPPLTPEGEAYRARHL
APYAPPVLRAPHRDGTTAAFRTAALDLDAARTHALRRLAEAAGTTLHAPVLTGYYRALAA
LTGRRDLVLGLAVTGRDESTRDAHHVFGPFAEAVALRPAPPSDGRSAADGFDGFDGFDGF
DGFDGFDGFDGFDEDLRRVSAESVAARTAGPLDLRTPQGLPRTAQFFFTFLDFTALGAPP
HTALTLRADDTDTALAPPPVGTDVFLAVRPRATGDPADGSGDSNGLRITARVPATALSSE
QLTAFMAELRRQLEQAPRTETTAATGTTVAAPPLDAALVGYLPAPRQLAAYAGLPPDTAP
GREAIRALLFPDGRARLLESVTTPLGRSGFVALPLFADELTGPPPVGGPATLAALTAHAV
DHAVSLGARSVSLAGMIPALTGYGYDVLRETSPATGSVLTTGHATTTVAVVRTVRAALAA
TGRDLAGLTLAVVGCGSIGTSSLRLLLTLSPRPPARLLLCDVPGSAPRLRRLAAALVADH
PALSVRVVEPADRAALPAEVYETADVVVTAVGGGPTTLLDIDRLRPGTVVVDDSFPHCFD
TGRALERMRDERDVLVVGGGLLALDSTETHPAPDLPAAVLTALTGATGRTGQHLALHLPG
TLASCRLESLLHARLADPASGMRLPRVHGLVDLPRALAHWDAAEAAGVRAAPLHLLDHIV
PPEALSALPPPSAPPRRTR
>A0A0N1G3P3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MLAGWSGRLSVAAVNGPSATVVSGDADALAELLEWCRSEGVRCRQVPVDYASHSAHVEAL
ESRLLEVLGPIAPSGGEVPFFSTVEGAYVDGRGLDAGYWYRNLRQTVQLESAVRELSTEG
YGAFVEVSPHPVLVTAVQETVEAADGTAVVVGSLRRDEGGLERFLTSAAELFVQGFAVDW
AAVLSSDRRVGLPTYAFQRERFWLESGTGAGDVGAAGLSATEHPLLGAAVH
>A0A0N1G1W2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MTASNERPEQHEQSAPHEPNAQGAQGAQSAQSAQLVQALRASLKENERLRQQTRQLTDAA
SEPIAVISMSCRFPGGVNSPEELWDLLIEGGDAISGFPTDRGWDLEGLFDADPERPGKSY
VREGAFLHDAGAFDAGFFGISPREALAMDPQQRLLLETSWEALERAGVDPGSLRGSPTGV
FAGVSGSDYAPALADVPESVEGHLITGNSASVVSGRVAFTFGFEGPAATIDTACSSSLVA
LHLAAQSLRQGECSLALAGGVMVMSSPALFVEFSRQRGLAADGRCKAFSASADGMGAGEG
VGVLVLERLSDARRNGHEVLAVLRGSAVNQDGASNGLTAPNGPSQQRVIRQALLNAGVSA
AEVDVVEAHGTGTKLGDPIEAQALLATYGQGRSEERPLWLGSVKSNIGHAQAAAGVAGVM
KMVLALQHGLLPRTLHVNEPTPHVDWSTGTVSLLTEHQPWARNGHPRRAGVSSFGMSGTN
AHVIVEEAPETTEPPASGAGADGRPVAWVVSAASAAGLRAQAGRLAAGVGDSSAVDVGFS
LVGGRAALGHRAVVLGRDRGELVERLGALECGVEAPGVVVGVGADAVGAGGVVFVFPGQG
AQWVGMAAELLESSPVFAARMAECAAALASHVEWSLLDVLGDPVVLERVDVIQPVLWAVM
VSLAAVWRSVGVVPSVVVGHSQGEIAAACVAGVLSLGDAARVVALRSREIVGIAGRGGMA
SVALPVAEVESGLVRWSGRLSVAAVNGPSATVVSGDADALAELLEWCRSEGVRCRQVPVD
YASHSAHVEALESRLLEVLGPVVPREGEVPFFSTVEGAYVDGRGLDAGYWYRNLRQTVQL
ESSVRELSTEGYGAFVEVSPHPVLVTAVQESVEAVDGAAVVAGSLRRDEGGLERFLTSAA
ELFVQGVDVDWKAVLPAGPPVELPTYAFQRERFWLESGTGAGDVGAAGLSATEHPLLGAA
VHLPGGEVVLTGRWSLKSHPWLADREPVPGAVFVELAVRAGDEAGFDVLEELTLEAPLVL
PTDDGDVQVQVQVGAVDGDGVRAVTVHARPDEPDAEWTRHASGTLTSGGVPADFDLTAWP
PPGAVPVPVDDLYADLTDRGMPYGPAFQCVRAAWRQGDDVFAEVAVDTPDQGDAFVLDPA
LLDAAFHVGALQDGTLPVAWHGLHVYATGGSGLRVRIRPTGGTLATGASTDTGSSTAVGP
VTVELADATGVPVARIASVVLGGPQTAAPGGSVPANSLFRVEWAPLDLPAPPATRDGLDG
VAWLTGIVGAALHPDLAALADAGAPGTVLVTLAAEPDTDVPAAVRTLTAASLELVQRWLA
DDRFAASRLVLVTRGAVTTGYGDDVPELTLAPVWGLVRAVQSEHPGRFVLADVDDPMSDD
ILVAALAAARDESELAVRGGAVYARRLVRAQPPTAGAVPFVPGDGTVLVTGATGGLGRLV
ARHLVTDRGVRDLLLVSRRGAEAAGAADLRAELVALGAEVTFAACDVGDRTALAAVLAAI
PAGRPLTAVVHAAGVLDDGTVEALTPDRLDPVLRPKVDAAVHLHELTKDLPLSHFVLFSS
LGGAFGTAGQANYAAANVFLDALAQHRRATGLPAVSLTWGLWAERSGMTGHLNETELRRM
ARDGVRPLSTAEGLALFDATTGDQPHSHFVTAHLDLAALRAKADTAPVPSLLRGLVQPPR
SRRAVTTGNGTGTGAGMSGDSDFARQLAGLPADERERTLLDLVRGHAATVLGHTSPDAVE
PARAFKEQGFDSLTAVELRNRLNTATGLRLSATLIFDHPSPRALVDHLHTTLLGTTDNAP
LPATAGPAATDEPIAIVGMSCRFPGGVRSPEDLWRLLRAEQDTVGAFPADRGWDTDELFD
PDPGRTGTSYVQEGSFLYDAGDFDAGFFGISPREAVAMDPQQRLLLEATWEALEHGGIDP
ESLRGSQTGVFAGTNGQDYAALLTNTPKSDDGYLITGTSASVVSGRISYAFGFEGPAVTV
DTACSSSLVALHLASQALRQGECTMALASGVTVMSTPDALVAFSRQRGLAPDARCKAFAE
G
>A0A2W1JQH8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Acaryochloris thomasi RCC1774|TrEMBL
MTHTPPVNEPRLAISHGDAISPEISAHRSLAAVLEQAAQTTAGLIYIEAQGNLLESSYAE
VLARAERVLHGLRTLGAQPQDKIILQATRNQSFVEALWGCFLGGFVPVPLSVAPSYDVPS
RKASQLLQTQQLLSAPIVLTNQALQQPIQRFCDEHRRDVSTMGHSPSIAVAAIENLRDGP
PDRQWATEHHQDPALILMTSGSTGMPKGVMLSTENLLVSAAGMAAANSLSAADITLNWMP
LEHVASLVMFHLTEVFLGCQQVQVANEWVLQNPLRWLDCIEQFRATATWAPNFAYGLIND
QADQIQQRQWDLSSMRWMGNGAEAVVGKTTQRFLELLKPHSLTQTAVSPGYGMTETCSGI
VHSHQFAPSTDTLVEVGSPIPGVSVRIVDHQDQVVIEGQIGALQVQGLTVTAGYYQQPDL
NREIFTSDGWFRTGDLGFLKQGRLTITGREKDVIVINGINHYAHEIEAAVEDLKGVAVSY
TAACAVSSAGEGAEQLALFFHPESSSGQDLALLLKQIRRTLSLELGISPDYLIPVAPEEI
PKTSVGKIQHQQLRAKFQAGAFTIQINKVTELLGDLSELQRPRNQVERQLAEIWQGVLQR
GPKADQGPTQIGIHDNFFELGGTSLLLVQVLHQVQNRLQVDLSVVELFQYPTIDALAQYL
SQSQSNDLALEQAQARGKKRRQKQVTEIAVVGLSCRFPGAENQEQFWQNLCDGVESITFF
TDEEILASGVDPQLLQRSDYVKASPILGEIETFDANFFSYTPKEAELIDPQQRLLLECAW
ESLEDAGYDPWCYDGSIALYAGASMNTFLLNNVYPNRHRLDNHDPMQMLNLSSMGGFQMT
VANDKDYLATRVSYKLNLRGPSVNVQTACSTSLVAIHMASQSLLNGECDMALAGGVSVHA
PQKMGHLYQEGMILSPDGHCRAFDAQAQGTLFGSGAGLVVLKKLEDAIASRDNIYAVIKG
SALGNDGGQKMGYLAPQAEGQTVVAAEAMAVAEVAPASIGYVEAHGTGTELGDPIEISAL
TRAFSTQQRQFCAIGSVKTNVGHLNIASGIVGFIKTTLAVQRQKIPPSLHFETPNPRIDF
EHSPFFVNTKLRDWPERSAPRRAGINSLGIGGSNVHAILEEVPVTQRSPTIERPVHLFTL
SAKTEQALKELAQRSVDDFRNHPELSLGDVCFTRNVGRAHFEWRVALIVDQSETLATSSL
VDLTTKLEDWLSNPQASNLYQGKVSPKNTSAKIAFLFTGQGSQYLDMGRDLYETQPVFRQ
ALEDCNTILRPLLERPLLDLLYPETPLEVQEEETPKSLLDQTAYTQPALFALEYALSQLW
QSWGIQPTAVMGHSIGEYVAACVAGVFSLEDALKLVAARGRLMQALPANGGMVSVVADEA
TVNQFLDHERSEVAITEGRPLAIAAVNGPESLVLSGERTAVEQVAEKLTAQGIKTTCLNV
SHGFHSPLMEPVLAEFEQIAQQITYHPPQIELISNLTGKRIGDAISTPIYWCRHIQQPVQ
FAASMKTLTQSGHNIYLECGPKPTLLGMGRALLEKPHNSDLNSDALYLPSLCFQKNDWET
ILHSLGQLYIRGVAINWENVDQGFEHYRVSLPTYPFQRQRYWLDPPPAQALLRTTARHPL
LGQKISTPLQQILYQAQISPEQSSYLQDHQVNTTAIFPGAAFLEIALAAGVESPNLDLPL
TVQTVAMEQALPLIGTVNVQTILQQTETGLTFEIFSQNSRADAAWQRHCTGSISQTTPLS
EPVIDLEDLRRQFPQERAVSSHYQACQTRSLNYGPQFQAITKLWIKPSAALAKVQLPTAL
SASNYCLHPVLLDACCQAIFAALPESDTSTLLPIGLDSLTLHCPASDCLWSHVQLHSVAE
TVTADLMLYRPDGQRVATVTGLTAKRTNLQAVLGMEPQAWQNWLYQVDWREQSGQLEPTV
MEPGQWLIFADQGGVGQRLAHQLAQRQQHVILVSPDPQESGSVHQLDPQDPQALRHLLET
LQSLPLTLQGVIHLWSLDAVNAEKDDAAISATIQQNCGSALHLIQRLLQAPSRLWLVTRG
TQRVNDERLDCSALSQAPLWGLTKTLMLEHPEFPAAVIDLAPQPTVDEHQALWSEILISE
PEVQVALRGDQRFVARLAPVTVESAHRQQKQTLQASVSSQLVIPERGTLENLRWQPQTRR
RPQAGEVEIRVRATGLNFRDVLNVLDLYPGNPGPLGLECAGDIIAIGAGVSGHQIGDSVV
AIATPAFSQHATTSIFAPKPTSLSYAEAATIPVAFMTAHYALNHLAKIGPNDRILIHSAA
GGVGQAAVQIAQQAGAEIFATASEGKWEWLRSQGIQHIFNSRTLDFAEEIQAITGKEGVT
ITLNSLTGKFIPHSLSITSDHFLEIGKQGIWKPKNVCKNWPHLTYSIVDLMQTMEKEPEQ
VQSLIKAVMEQFQAGELKPLPYKSFSAAKVVNAFRYMQQAKHIGKVVVEQAATPVVPKQS
KNPLAQLATGSVLITGGLGDLGLLVAQWLADQGARHLILVGRRSPSPKAQTQILQLEKSG
VQVQVMQADISQRNDVTRLLDPYHRATASKVNSTNVAPKTHVNNSHPQATPPLRGIIHAA
GILDDGMLQTLNWEEFESVLKAKVNGAWTLHQLTADLDLDFFVLFSSAASLLGSAGQANY
AAANAALDTLAQARQSAGLPALSINWGPWEQLGLANHINAGFQGMDRIEPQIGLAVLDHL
LRQSWAQAGVLPIHQSQWTVPTGMSDFWSELAVKQPADWLEALRGACDRKSLLFQYLRSE
VARLLGRDASALNDPETGFTDLGLDSLTTVEFRNRLQTALSCSLSSTILYDYPTLPLLTE
YLMHQIFPADSSVKPASTNLYSTSLNKLSEADAETLLLLQLEQLDSNFRKN
>D5UX38|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / CCUG 35730 / CIP 100753 / JCM 10117 / KCTC 9821 / NBRC 16120 / NCIMB 702349 / NCTC 13040)|TrEMBL
MSEEKLRSYLLKVTEDLQKTKRELDRTRAEATEPIAIVGMGCRYPGGVDTPEGLWRLVRD
RVDAVTPFPADRGWDLDGLYDPDPDAVGTSYAREGGFLADVAGFDAPFFGISRREAIAMD
PQQRLLLEVAWEALEHAGIAPASLAGTSTGVFAGVMYQDYGRRLAFPPPEVEGYLGAGGS
GSIASGRIAYVLGLEGPAVTVDTACSSSLVAARHAMTSLRQGESSLALVTGSMVMSTPVA
FVDFARQRGLAADGRCKAFSDGADGTGWGEGVGVLVLERLSSARRNGRRVLALLEGAAIN
QDGASSGLTAPSGPSQQRVIRAALADARITADDVDVVEGHGTGTSLGDPIEAQAVLATYG
AGRSAGLPPLVLGSLKSNIAHTQAAAGVGGIIKMVMSLQNATIPATLHADTASTRVDWDS
GRVELATEARPWPAHPDRPRRAAVSSFGFSGTNAHVIVREAPTDDAAPPAPEPTPDAVPE
VEPPAVPLIVSGKGQRALAAQLDKLADFVTGEATSIPPDTRAADIAYSCATTRSALSHRW
AATVPVGASPAVIAERLRAGADEIRSAPPRQVPPSGRTAYLFSGQGSQAVGMGAELAHTY
PVFAAAAEEIGAEIARQTGIDIAAIMFGDPAVYAAELASTRISQLALLTHEVAMYRLLES
WSLTADYLIGHSIGEIAAAYVAGVFTLPDVVKVVAARGELMGSTAPGVMVSVRVDEREVA
DALAAAARTGAPGVAIAAVNGPRATVISGAAQDVAAVLSQPVAAAWKTKRLDTAHAFHSP
AMESVAERFGEILAGVTMSAPRRKVISTVTGAPAAAADGDLVTPEYWVSHLLGSVRFGAA
VTSALDNGVTRMLEVGPDAALTSLARAADTERPLTAHPTQKRHQPQAVQLLDAVGALHAS
GADVNWEAVFGPHHPRRVPLPTYAFQRERLWLEDGGADHVGGRERLAHPILTSATEHPGS
GDIIVSGSLSPTRIPWLREHAVAGTPILPGTGFLDLALSAATHIGADVIETLTIAAPLSV
ADEVSIRIVIAPPDADDARREVRIYSRDPGPLAAEPWRLHATGVLGGSAAHDGDVDSGGG
EGKRLAVEGMYQRFADNGFDYGPAFRAVVDASETTGVVHATVRLAPGLPQAGHALHPVFA
DAALHPIALSTALLSVTDGRGRMPFEFTGVRRYGHPSGATPTSGRVRLEATGPDSVAVRI
ADDHGAPVVTIESLVLRAASPAATGDGAVGEFFTVAQRPLPDAPASGAARIGALGPDPAG
IGELLDRSGVHVEAYADIPVLIDILGTGALPPPAVYAVIDLADRGTARARQLRERLCETA
DLLRAWVTTEELAATPLVLVIPPSGDSALVAGVRGLIRSAQNENPGQIRVVTLDSVERLG
AAPLLTALTAAEHPELTIADDGTVRAPELEPLAVSATGSSAWATRWSVGTVVVTGANGAL
ATELATHLVREHRVTSLVLCSRRGGSAPGAAGAATTLSELGASVRHLALDVGDADAVATA
LGPLATEITAVVHAAGVIDDATLAGVDADRLDRVLTPKADGALALRSVLPHADLVLFSSA
AGTLGGVGQGAYAAANSWLDGFAADPPAGAGRVISLAWGPWSDDHGTDPDDAPRPNRSGL
RAYTVPGGLAAFDGALSHVHGTGQGGALVLLRVDRAGLRANSGSAVPLLARMVPQRRRTV
PRSHEAAAAEKKRPSDVLHRELAVVLGFAPDAEVEAGAALSDLGFDSLTAVDLRNRLTRE
LGVRLPATLVFDHETIDDLGTYLDGLIDDTSTSGTSPATTSGEDVAAEPGGGLLLPIYNQ
VFTSGKWTETFAFLRSAAALRPEFSGPADIAEGLPRIATLAPAVAGAAHLYCLPSCIAMG
GIHQYARIASALRGKRGVSAVGIPGFGVGESIPASIDAVVAVQGEAIAAHAQAVGSDPVL
LGSSAGGWFAAAVAAYLENTARTVAGVVLVDTYLPQSNLVDQFGLALMDGMAEREGTFVT
LTDERLSAMGWYLDMWKHWQPDSLSTPTLLARATEPLSAGLAELGTDWRASWPHRHHAID
IRGNHFSMLEQHSADSAAAIDEWISSAVDADRKGRVLS
>A0A7U4DYE5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Serratia sp. AS13|TrEMBL
MSETYLTHGQKTHGDIAIVGMASHFPDASNLHEFWENITNKCDSLTDISSMSDAAYWRKE
DFYDPDATAADKTYGHKAGFVPAIEFDPVAFKIPPAIMDSISTAQLFSLYMARQVMQDAG
LVDKKDAQVDRDRIGVILGGGGNGNTSFSLAARQQAPYLREIMIKSGLSTEVADDVIARA
HELYLEWNEDSFPGFLGNVACGRIASYFDLGGTSYMVDAACASSLAAIKAAIGELNSGSC
DAVLTGGVNLENSAFSFLCFSKTPALSKSNRSRPFDRDSDGIMLGDGVGLLVLKRLEDAE
LAGDRIYAVIKSLEASSDGRAKSIFAPRYEGQIKALKRAYASAGILPGDIQLIEAHGTGT
ASGDGTELKSLRAVFDEYRLPAHSIAVGSVKSQIGHTRCAAGAASMIKVALALHHKVLPP
SINVQQPMEALSVEDSPFYLNSETRPWLRPLDDSPRRAALSAFGFGGTNFHAILEEYEQD
AHGAYRLNESTYTLLFSGDNADQLLQRCETALESFSTGSAARALRQHLAAQDINTLEAHQ
ARLLLVATSAEHAGQLLQTAVKQLRNNQDKGWEHPQGIYFQPEGKALSGKVVALFPGQGS
QYVNMGREVAIDYPEMRQALETLDKFAADVRGHGLSDIVYPTPAFSDAERDAQRERLTDT
ANAQPAIGAVSAGYYAILKSNGFTPDFVAGHSYGEVTALWAAGALCDADFYRASLARGMA
AASAVAQNEGDGGAMLAAALTVEACEKLLVRYPDIVLANDNSPAQVVLGGATARIHALYD
ELKAGDVQCRILPVSAAFHTPFLQAACAPFLESLSSIRFDTAHCTAFSSASAAPWPADTA
TYAETLAQQMVMPVRFRETIEALYQRGGRLFVEIGPKGVLGKLVADILKGREHTLISLNT
GDSGDDRLQLARAQARLLAEGVKLNALDRYVRPAPEQGDLTGRLSCRLNGGFYLSEKNQR
RRQHALREGDTEVVERFIRARQGAAMPVATVTAAPVTAAAKVQPAVAPLPATASPLFQST
KSNTSEALHKRDQAMEQINQRVESNDNTPLNGVLQAQQVMSQLHQQFQTNQKEYIQLLDS
LLNKQYALLENFRDHHNLPTILASLGQSVQLLDKNLELYHSNHERYFSTQQSLFQPGQAP
MPVAPRALNTPVQAYPQAAVVSVSPVAAPVHPVAAPVSLSAPRPSVPEMPVVAKAAPAPA
PSAPAPQAAKPTASPMSPDVEAQLSRFASITEAEITARLVTIVSDRTGYPQDMIDANMDL
EADLGIDSIKRLEIFGAMFDAFSADAGIYHDASKNKDLETFDIEALSNVHKMSLFFKEMI
DEIIADIRRKQGLDEGEETPDTASSKDFFTEDNQRESEAELPADALRASEDIGGDAKLRT
LGFVTSTVVVAEVESAKKSSTESQQYVAPAVQSATEETVSVKPHTQRFSVTSQPLPTPDC
DTQTFAVKRHWLIVDEGKTLIDDVTKQLTQLGQTVSVLALHSAAAKNKKQGKTSHVYSLA
HPNEATLDTAITEIEQARGALDGVIWLQATREKVKKVTDIFSANGYRSLETAFLLAKRLQ
ESLNRGEQHPGWFFVVTRGDGQLSISRAGGLSTMLPAGISGLTKSLNIEWKTAFCRTLDI
DAGLKSGEAVSILLEELQDARRDLAEVGRSAQGERMTLALSAAPTENEETPPDVSERDVL
VVTGGARGITAKCVIELAQRSQAHFILLGRTDINAPLPAWAQGTATVAERKAAAIAQLQS
EGVQPTPVKIDAMLSGLLHSDEINATLHQIAQAGGEAIYRHCDITDAQQVAAVLNEAQQV
VGPITGIIHGAGNLADKRIEKKTLGDLRSVFDVKVRGLENLCRALDITGLRHVMLFSSVS
GFFGNAGQTDYAMANETLNKFAWLPLQAEGQPTVRAINWGPWDGGMVNDTLKRAYDTHNM
VIIPLETGTELFVREFTDAAHPQVIIGGDNYRAKRRLTAPAERYEVTRLLQPQNNPFLQH
HVINDNPVLPATAAIAWMTRVCEERFPGYQLQRVSHFTVLKGIVFDGNEAERYRVSMTPH
AGDRPDDDHLAVDLIISSQQEMKHYQATLLLALQGREAQFAELHGDLDVAIPLAVPLYGD
MTQGAQLFHGNAFRGIQQVVHIDEQSLILKCRLPSLEAQEQGQFPANSFNLFINDVGLQL
PLLWLMQQSDKAGLPAAIGVIEQYSPLDFDQTFYASMRITSQTATLLLADITLHDELGNV
YSRFEKVKFTVSTTLRSLFTCTDEALEKKEHR
>Q1JYV0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Desulfuromonas acetoxidans (strain DSM 684 / 11070)|TrEMBL
MTDSGAQTQTTDKNTAAKPLAIIGIGCLFPQANGKDAYWANIKGAIDSITDVPETHWRTA
DLYDPDPKTPDHTYGKRGGFLDPIEFNPMEFSIQPNILEAIDTSQLLGLIAAREALRDAG
YDPQSDFARDRVSVLLGVTGALEMVIPLGARLGHPQWRKALKDAGVPADVAQEVVERIAD
SYVPWQENSFPGLLGNVVAGRISKQFDLGGTNTVVDAACGSSLSAVHMAAMELACGRSDM
VITGGIDTFNDIFMYTCFSKTPALSPSNLVRPFDHQSDGTLIGEGLGLIALKRLEDAERD
NDHIYAVIRGVGAASDGKGGAIYEPSASGQKRTLIDAYRQSQVDPRTISLLEAHGTGTKV
GDATEIKALREVYGESDGAPWCALGSVKSQIGHTKAAAGSAGLIKTALALYHKILPPTIN
VEQPQTVITEGNSPFYVNTVTRPWLANPNHPRRAAVSAFGFGGSNFHCVLEEYLSEPTCC
DFSDAPLLFALSGQDRSTLETALGQLASAPKDAVRRRAAQSRQAFNSNDPHRLLFVVDKP
ADLPGVIDKAKKVLTTQAPLNGTPQGIWYGQGPSQGKLAVLFPGQGAQYLQMLADLSCHA
PQLLAQLQDGDDVLSLDDGTSLSSLIYPHSLFSSEQRQQAEQRLQATQHAQPAIGTVSLG
AWNYLRNHYGLEAQAFAGHSYGELTALCAAGCYGSDDLLRLSRLRGTLMAGDGSDKGTML
AISAPLDEIEQMIREENLCLVLANHNTPNQGVLSGEREEISRAETLCKQRKMRCTPLDVA
AAFHSPLVAAASKPFHNALQEIDVQVPQCAVYANKTALTYPQEPGQITTLLAEQIASPVK
FVRQIEQMYADGFTTFFEVGPGARLTGMVKKILADKEVQTIALDASNGKRSGLSDLAKAL
VQLAALGCPVDLSRWDDQFVTRMEQLPEPKPAKMTVTLTGANYVKEKPARPASKRHLVDA
DQIPTPTPVAQPTTQSVVSHASNDDVAALKSLQENMAVLQQMQEDTARLHQKFLEGQAAA
VDTMRVLMDQQQPTMAATRPSTPPAAVPKAPQAPRMTAPQPSAARPVSQPAPQPNAEPGN
SVQDALLDVVAEKTGYPQEMLELEMSLDADLGIDSIKRVEILSALQEAVPGLPAVQPEQL
GSLETLRQIVEALGAVDLSAPQVVASATAAASGSDTNVQAALLDVVAEKTGYPQEMLELD
MSLDADLGIDSIKRVEILSALQEAVPGLPAVQPEQLGSLETLRQIVEALGTVDLSASPAA
SGSNTNVQDALLDVVAEKTGYPQEMLELDMSLDADLGIDSIKRVEILSALQEAVPGLPAV
QPEQLGSLETLRQIVEALGSVEIAAPTVAVVASAVSQTAGTLQTALLDVVAEKTGYPQEM
LELDMSLDADLGIDSIKRVEILSALQEAVPGLPAVQPEQLGSLETLRQIVDALGATDTPQ
PPAAIDQAPPSAPSASTTAKSVQEALIAVVADKTGYPQDMLELDMSLDADLGIDSIKRVE
ILSALQEAIPELPAVQPEQLGSLETLRQIVEALTQQAPGAEEQTAIQTPVVTTETPAVPS
PSQVSSQPVAPATVKEPDPNATVRREVIQLDVVGQQRQPYTLSTNAPLWLVDDCSSLVPT
LASTLKGEGYPVKIVSPTQTEVPDQLAGLVIIAPEIGTDSHFLRDAFSLVQRCAPALKKQ
SAQQSACLVTVSRLDGQCGFGSQSLLRDPLSGALAGLCKTARLEWPELTCKAIDVSDTLT
DKELSTALIDELLLTGPIEIGISREGLTTPVLVDAPLPEDSDSIQMTGDDIVVISGGARG
VTAEVATHLAQCGQPTLLLLGRSALPEVEPDWLAAARTDADIKRTLMEHAEAPLKPRELN
DQCTRVLQQRELTANLDRLRQAGSKVIYKALDIRDEKAVAEALDEARQEGTVRGIIHGAG
VLADRKIEDKTLEQFDQVYSTKVAGLQALLHASANDPLRFIVMFSSSTGRFGRVGQVDYA
MANEVLNKTAQALSRQKTDCRVLAINWGPWDGGMVTPALKKLFADEGIEVIDLAAGSQYL
LQELTRQDGQVEIVILGEHKKPNDHDQQDAETSVDLSASPITECYPELALTLQITPQTMA
VLQDHVIDGMAVVPTALIIEWMAHGAMHNYPGMQFIGFDNLRIFKGIRLTADEEYDVELR
NQQGRFEEDLMRIPMQIVAANSKRIHASGDILLSSFRELTAPTITPLSVDTERAQSHEQI
YASGQLFHGALLQGIQQITGEGPEGIVGVAESAPSPQQWMASPLRYDWLTDPMILDSSFQ
MMILWSFAEKSQGSLPMFAGRYRQYRESFGTTPIYIQCRVVKQSGQVVEADIDFIDANTR
EIVARLEGYQCTMTPTLEQAFANNTLV
>S3JVP4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Microcystis aeruginosa SPC777|TrEMBL
MARLISANQDLLWLPSIVPGQDEQAQMYRSLATLFVNGYSVEWTKVFKQGKRISLPTYPF
QRERYWLSNSEFSLGQIKTQLHLFIRDFKKLATGDMIFEGEVSSLNPSYLEEHKVFENIV
FPATGFIEAILAASQKIFNGHFVTLENVSIHQGLLLSPTPSIIQIIFRPKKSSQLIYTFE
IFSSDSAQEQWLLHVTGEVKPKDIQSLAASELNPTKLERENPKESISIREFYELYQQMGI
RYGEQFKAIQELYSFKKGSQAKISINPSLADRRYYFHPVLLDACLQSIGAAFPEIHGQEL
YLPYGFSSLEIFLNPTSQVWTEVQVISDTNGEMRVNVNIYDEQGQLCARFTDLTARRINP
AILQSLWQEKSNNCFYKVEWKKLSSMPTVAVDPQNSWLVLVRPETDLNSLINLYKKAGEK
VITVEMGQNYQCYSQDFFVINPAQKSDFQRLYQEAYPSGEFPTGVVFCWESSEAEDVLDT
VDQSSHAVLNLVQTLTNNWEKLPHLWLITRGANKIINDTALSPQQSHLWGLGAVINQEYP
KMGCVCLDLPIYKEANEAELLFNELKCFLHEFRLALRQGNRYAARLVSASLPISEKRQFI
NQSGAYLITGGGGKLGGLVAQWLSEMGASHLVLCSRHVKSSTELIASLVEKGTKVTLIEA
DITSPTDMKNLFSRFGADLPVLRGIIHAAAVLEDGLISNQSWQKYQKVISLKVAGTLLLD
RYTRSLSLDFFVSFSSAAVILGSPGQSNYAAANAFMDALMQQRQSLGLPGISINWGAWET
GNQIDQQRFANWGLQMMPSEQAFQYLSQVILGDITQGMVLDIDWSIFNQTFNISQPFFSE
VLTLNNQKQISPAKLLEQLKSVSIDERITALVEGLEKILREVTGLNDNKVIPQQTSFLDL
GLNSLMVIEFKNRLERDLGCKLPSSIIFDYPNLLSLSNYLREEILANHLDFEIKINPIPD
NHNPYDSLSEDELARLLNQKLTELDQYGG
>E3IWP9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia inefficax (strain DSM 45817 / CECT 9037 / EuI1c)|TrEMBL
MHVSPTSGAPSAGDSDGSANRLRARLTDLPESGQIRVVLQLITELVGVLTDRDSSRIPVD
PLVSWRRLGIYRDVAGRLRSRLESETGLALPATLLFDRPSPHALAAYLCARVLGSDDEAD
VALGGPMGGAVAGDPVAIVGMACRLPGGADSPAALWELVRDGREGIVGLPTNRGWDLDAL
YAPDREQPGTIYTRHGGFLPDISLFDPGFFGIGPREAAAMDPQQRLMLEISWEAFERAGV
DPGSLRGSRTGVFTGVSLQDYGPPWHRAPAEAQGQLLTGNALGVVAGRVSYTFGFEGPAL
SVDTQCSSSLVAIHLAVRSLLSGECGLALAGGVTVMTTPGMLLEFSRKQGLAPDGRCKPF
SADADGTGWADGAGVLLLERLSDARRHGHEVLALVRGTAINQDGASNGLAAPSGSAQRRL
ILAALASAGLDPGDVDVLEAHGTGTALGDPIEAEAAVATYGRGRPPGRPLHLGSLKSNIG
HTQAASGVAGVIKMVQAMRHGLLPRTLHVREPSPHVDWSAGGVSLLTEQRPWEAPEGAPR
RAAVSSFGVSGTNAHLILEEAVAPPETSEPPGADRPAATTSRPRAAHAPAPVPIVLSGRT
AEAVGANAARLAGHLDRHLEITPLDVGLTLSGRVRFESRAVVIVSDERGGHAHLVNTLTR
LAENRSTAGLISGVARPAVSGGRTAFLFTGQGSQRPGMGRLLYRAYPEFARALDEICDRF
APLLRRPLRKVMFAPAGSADAALLDQTAYTQAALFTFQTALFRLLQSWGLRPDTLVGHSI
GELTAAHAAGVWTLDDACALVAARGRLMQECRPGGAMTAIRAGEADVRSSIAGLAGQVEI
AAVNGARSTVIAGDADAVARVAADWTRRGARTKRLTVSHAFHSPHMDGMLAAFRTAARAV
TYHPPSLPVMSNLTGGAATEADLMSPEYWVRHVREPVRFLDGVRALHRDGVRAFVEIGPD
AVLTALVPGCLPEGAAAEDLAAVATSRAGRSEPETLLVALAELDVAGVAVDWARLCAGRG
GRPVDLPTYAFQRRRYWVDGAAVAPAPVAAASTGARATGPDSWRYQVRWEPLSGERAAAA
AAGHLATGASIRGTWLVVTGPAGIDGQTLSRLSWLLERLGGRPVHIPLAVADAERGRLAA
VLSKHSSSRDDQIGGIVSLLPFEEQPNTLHPGLTDGLAFTCLVAQALDDLGQNAPLWCVT
RGAVSTGALDPVTAPTQAMVWGLGRALALERPDAWGGLLDLPATLDDEALALAGVALTAP
GGEDQLAVRGGALLVPRLVPAEPADATAASWRPSGTVLITGGTGALGAHAARRFARDGAA
RLVLVSRRGPAAPGVGELVADLEALGSTVTVEACDLADRDQVTALLDRATGFDEPLTAVV
HAAGVLGPVAPLRELGLGELEQVVTGKAGGAALLDELTSPANGDGVPLEAFVLVSSISAT
WGSGGQSGYCAGNAYLDALASHRHGRGLPATSVAFGPWAEAGLGAEPTLRDYLARRGVAP
LPAEPAVTALAEAVAAGTAATTVADVDWGRFLPPFTAPRPTRFFDELSERPVRAATPPAA
AGLPVDPAAGDQRAGLARLTGSERDRALTSLVRDEAAAILGHASPDEVALDRRFLDLGFD
SLASVQLSRRLSTVIGQQLAPPVVFEHPTVTELAAYLGSLVARQDRAAPSGQLTPAGVRD
LYRQACSIGRFVEGVEVLQAVAKLRPVFHELAEFGAARPPVRLASGPASCALVCVPSMVA
PSGPHSFARLALHLHGQRNVYGLSLPGFDEGEHLPATSELVVDLLVDLIAGEFADAPVAL
AGYSSGGWLAHAVAAGLEARGQRPGAVVLLDTWLPGDRIPTEDIQEELRGIAVNDQAFAL
MTEAQVTAQGAYLTLFEKWKPSPVEAPVLLVRAEERMPQLSPDDQATIAEHGWTTDWEIE
HLTLEVAGNHQTMMNEHAASTAQDLHRWLTSLDQTP
>A0A023B0K1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Gregarina niphandrodes|TrEMBL
MALPPLYFLTEKVFGDTGRTPHKHAGLWGVGEVGETRSRTEDGALCRVANIDLQGEGIAP
ASVLEFCERYAATRDGFETELIFEQLPDDTNVGTTGTGTTSGAAVAVTAGLTETGRVDGE
RPSESTELTTIVTESVTGVVTEPVTDRLVSAPATVVGPAELHMKDRGAITALTLRGQSQK
TRLTPPNTYLEVRVRAVGLNFRDVLNVMDLYPGDPGPPGSDFAGTVTQVGPDVKHVKVGD
HVFGIAPGCLKTYALTDSLLTTRMPAGFTFEECAAMPVIGVTVEHALGTLAGVKRGDVVL
VHAVTGGVGLVALRYCLQVGAEVIGTCSSEMKQKYAREAGASCVADSRNADSFRRTVANY
LGDRKVDVVLNSFIEDFITHSVDFLKEDGFFIELGKRELWSVEQMQAAKPGVHYHRVQVD
VDMEKNPAWFQNALTKLRDSMAEERLVPPPLELYNLYHRERHGVAAFQQLQKAKHIGKVV
VSIPSVFGRVDDCASSRPERQAILITGGFGGIGLTVARWLAEEGATDLVLVSRSGKPNTE
MAKQESWRRLSELERLGAVRIHAVAAAAEDSEALMAALAGLKEQLPRLRFVFHCAGVLDD
KLVEQQDLESVKTVMNPKIKSVYMLSRALEKTRLDRQVELFIXFSSFSARFGNYGQTNYA
AANCGLDAFAAYRTRRGKKTVSIQWGPWIEQGMAAKLASHLASVGMKGITNEVGLAVLHD
AVIKSVNTQCVDVFPTVTCVQAFDWDLFFDRYSERPPVLSEIATQADASGLNKAARDKLV
AMAPEERVKFVHNVVADTARQILGTAEMPSMDSPLQELGIDSLGAVEFRNALQLKLGVKL
PVTALFDYPTLGAINTFLFKEIDAMVAASGGGVVAVATATGAPTAGLGGVASDRFERLAV
VGMACRFPSYCRSPASYWDMLLSGRDCMVEVPFDRWSVDTVFDPDPDVRGKCYVAQAGFM
ADVELFDHRFFNISAAEVACLDPQQRQTLETSYEAFVDAGFNRTTLAGQSLGVYIGCCNT
DWHFVDATANSEKVTTFSSSGGATSLIANRVSYALGLTGPSHTVDTACSSSLVAADNAFY
ALRGGACEGALVGGVNCMVTPHLFVLLGKSRMLSPTGRCYTFDARADGYARGEGVGALVL
LPVSKAKALGLAAYALVAGSGANHNGRSASVTAPNGPAQQDVIRQAMRQAGVEPGLVRYV
EAHGTGTALGDPIEVNALKGVFAHAVSNREPLIVGAVKTNIGHLEGAAGVAGLIKLVLAL
HQRQVPPNLNFQTLNPHLDLSGFNIAFPYKTKALLPTEGVIAGGVSSFGFGGANAHTLAL
SVDAEPDLARKPDLPGRTEGRALDTQVRTQVGVQAFGGRRLCFVFAGQGSQYAGMGKSLQ
SEGCEAAQKVFAEAERVSEAEDLFGIGEGAWVRISEVLWGSRSTEIDQTRFAQVAVFVHQ
VALFEELRHRGLRPQVVLGHSLGEFAATVAAGVFDFETALRLVALRAREMASLDPAGGEM
HACRASAVNARTVIADLGLAHTCALAAENGPNSITLSGTAAAVRKVLETLKTTSKKLDTS
HAFHSPLIATATDTLRPSFEQILTGRKEVRVEGSTGSSDLPVFVSTVRGTVVDAAELAST
EYWMAHILQPVLFSQAVSSASADGKCAVFLEVAPRAVLSKVVKPCLPRASAGDTKILAAL
DPAQDASEPAQIKAIAAAAFVAHTHVWNHVRSHWGYSGHPFLGDWRGVQRQTVTDPRGLS
VIQLSLEHTLDQEALDYVNDHVVSGMCLMPGAGIAEMAVVAAARHLNSSFSQDPLKLGPQ
WLSLRSVQFLTPMVVPARVTDAFRVRLTRSQGGSGDRTGDLVISSSAFQDDFVHNATASG
CATMEPPTEATCPIGEAQERLANLQSQFPQEVDVAQHYTTLVNVGLNYGPRFQTLKALHV
GDGEAVLAQLHSHAYYQRTSGAARTAPSLMEMAFRTAPGVLDGAFQAVAAVLARAGVRQG
MVPVLLEDVSVGRVSAGCVLHCHAVLTKRTARTAIVALRLFNQWGRLVARFGGVTLKAVD
AAPVQFPRELYWNTVWMRVDQLTDEDDDGEHDDGEHDEDQEQGKGKQAQGGTRNLEGETV
VSDTGAEGEGVVENLMKVAGSVLAGDWLFVGSSGVAELDKAERMLEGAVRVTHRAPPKND
TEADIVLRERPWTAVFQLNGCCTSEGYDECAVLGDALMLFKAYGRLFQNAEKDVALPLLA
VATVAAWAVPALGRSGRCVGGGGQYDVA
>A0A4U8W9A1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia cyriacigeorgica|TrEMBL
MPDYRLPNGATPVLISSDTAEGVAAEAAALLNYLRQRPRVSPDAVADMLFRTRSARRRRA
LVLAGSRTELLEALAAIAADRAHPAVISSSGAATARRIGFVFPGQGSQRAGMGKLFYEAS
PEYRAEVDACAAIHLERYGHSQPLAYLLGTEGGYQDIVWEVQPALMFHMAGLAAMWQAHG
VQPHATIGHSQGELAAGWVSRVMTRRDAVLAVTHRARLVDDLCEEGRYSMAVLGMDREEC
EALLARNSGWAELSVVNSAHILAIAGDRDTILEMVETASAQGKFAKEIKVAYPAHTSYLI
GVREEMEAMLGDEMSSPTFDPTEITCYGATLGGPITPDVAHRQYWYWNLRNRVRFDRAVI
GAASEVDTFIEVADHPTLQLAIQENLAAVPGGPHDFQVLGTSHRTATSLEEFTRNLAAVA
VNDLNYDWKALRVPDSPTRLPLPNFPHTRMNSRHLWAPYRDETDTASAAEVAPARLVEQW
DRLSRRTMAPERSMTLIDPTGRCADLAAAVRERAERYGATVTPFEGAPVDGANTVVLLLP
PSAADTETAAVEEFAAFATDQRWRAALGPQVSECWLVTAGAEAVADDDIPGLATAAAAAA
FRCIALEHIGVAFRHLDLPADYPDSAMKTSADRVLEAVHLTGEPELAVRAGGLHAKRIVV
ADAAETTGPDLSEVLILGGTGHVGLEFCAELVRAGAGRITLVSRRGETPAVTAKLRAIRA
LGATEIAVVSGDLTDADTMAELAARYSGNPVTLLMHAAVDYVYSTDADADAAARSAAAKV
IGFAAVLRALPLTDDATVLLCSSFAASFGGWGQALYAGTNRMLDAMASALRAGGRACASV
QWGLWVLPAEADAAVHARIEGSGLLPMDAGAAVTAGLAEPNGNSLVLAADWARMREVAET
VGLAAVFAPAFDVLVETTAQPVTASPAPAPEQEQVSAAEPEAATPADADFSELIRRELDR
VMLSDGSDRIDGSVPLVSLGMDSLQALDLRKRLKAELNRDLPVAAILGGASLDEVVSLMS
ENEG
>Q4ZND0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudomonas syringae pv. syringae (strain B728a)|TrEMBL
MSNAVHNIYAVNRWRPIAGSPSLATDESVLVIIPVTSAAGVSPNRQRLLSWVGGQAHCSF
TALDTLERMTATLADCIPGKIKSILWIGGSLDVSVHAEDQGLQYGIEEKIFFRFFKALLE
LKADEVRLSITVVTKNNFNVNNEGTNTAVNAGLHGLVGAAAKEYSHWTISLLDVDDAFVA
RATSNPSLVRSSQGIEKRKVKGQTYCCRDDQWYAEHLEVLPVENGSGPVKPIYRDNGVYL
IIGGAGGLGQAWTESLLQRHDSQVIWAGRKAINDEIRHSLRAMERLGRAPLYVSVDATQP
HQMEQLRHTILRQYGRLDGIIHSAIVLEDKTVANMSETTFSSALAAKVDICRNIENYFAD
LDLDFIAFYSSIQSFARQAGQSNYAAGCTFKDSFAHYLQAKCATTHVRTMNWGYWGTVGI
VSDASYQKVLEKSGMASINPTIGMLAFKALMAGDHLQASFIAAYDPEKITLIDKVTLHQN
TTEFGFVQSTTQLNNNVVEGCMMEYVYRNEHYMALREEGVFYLEDMDSYLCRIVAADLET
LGVFSGTEFSVENVLRKTDIRAGFSRWLTETLMSLVRQGYLRHDAGQFSKTAEFPESDAS
AAWLSWNTAKVEWLLDDNKSAQVKLVEALLIHTKEILTGKIKATDIMFPDSSMRMVEGIY
KNNRVADYFNLVLSRTVVDEINTLLAADPQRKIRILEVGAGTGGTTAVLLKHLAPFHANI
AEYCYTDLSKSFLFHAQREYGPGNPFLRYEIFNVEKSVDDQPLQRDYYDIAVATNVLHAT
SDIAASIRRVWEVLKDQGSLIVNELSRNTLFNHLTFGFLDGWWLYNDDHIRVPGSPVLEP
ATWHNTALQVGYGSTQFPAELAHDMGQFVMLMRAQKHAASLAPKVVESGSSHSSGNESSM
LTPSNTPSAVNVAMLKAKSQAFFTDLIADVVQLPVDEIALDLSLEKLGFDSILVVTLTNK
LREHFEQVSSSLLFDIDSVEGIIDYFIEQDKQALAALLGIDFSDAQPPSAAPVAVASHTQ
APASAPAVTQFDVIDLGAFSLQEVDAPSASLPQVSDFQETYPEPRRSGDIAIIGLNGTYP
GSRTLDEFWENLSQGRDLVTSVPKARWEQTGFNRVENPENFKGGFIDGFDQFDAEFFDFS
ETDALLTDPQERKFLECAFSVLEDAGYTKESLAESDMTTGVYVGAMYQEYQLHSETAKGL
YEGQAISNSFASIANRVSYILNLEGPSVAIDSMCSSSLSAVHLACSALKLGEIDYAIAGG
VNLTLHPNKYGVLKQGGDLSQTGKCASFSESADGYVPGEGVGAVFLKRYEDALRDGDHIY
GVITGSLIVHAGKTNGYTVPSPKAHSKLISKVVQQAGIRSADISYIEAHGTGTHLGDAIE
IHGLRQAFSIDQDSAQQGKFCSVGSVKSNIGHCESAAGMAGLTKILLQLKYQQIVPSLHS
KKINKNLQIEKTSFSIPQLLSHWRLPNKEVKKRIAGLSSFGAGGANAHFIIEEHEEVSNQ
VNYTMDYPELIVLSAKSKEALHQRAAQLLGYIHYNAQQNTSLNNQPRYWLGNIAYTLQTG
RTQMPYRLSFLADSIEHLEDNLDAFLNDKKGKSPLHVCYASEMDATAKLLYEDNSLELIL
SEWLKQGKYQNIVALWAKGVVINWGGLLGKRGQRISLPTYPFSQNRHWLPMGNHTAGVSQ
KVEAASVQQRVKTVAAMVEPVVEKVAGKIVQKTVEPVVGKPFITAPVAVEKVTAEPKSLF
IHRWNKVDVSPHPKPAQADTKICVVGLDTLDYFQRDLETCGLDAGSSEWQQVLPNGFAQS
FADLAKSVSRQLAKKVKAWLADSTQPLHLQIIMPFDRQYQLYAALTGALEQHVLGAANVK
LTIIYCEALCSFANISTLINRAADTQTHIAEYLCAHDSIYAGSVQKVSQPESGSLLNDNC
VYVLANGLNEVGQSVIRAIDDETSGCHIAILGDALSAPDIDEQIGLLQNSLDNTKVGYYA
AELDDRKSVFNALLLIKDQLGDIQGVHYIVPADDKVQQHKEPLKDKALIRHLAALINLDE
ATYSFDSQLQSFSIVMTVEEHDSKQLNTLAKTFGRYRAALQGTGYREGKTVALEVEGNAA
NDIATAFIHALDKNHSDEQFAFIWKAATLADNTPVIQPQVTVEPPVASPAPLAAVAQKQP
AYSFDGASDELQATVSWLVSISSELLDKESASFSPVATFTENGYESISIVGLCELINSRL
GLAISVVVFFEHDTIQSLAQYLVAEHGDQIEEVLETDVEG
>A0A0N1FWT0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK006|TrEMBL
MPVSKFDTSGLFAVEDIVIALNPFAVPSARVTAAAVRAGGLGVLDLTAGGRRAAAELASA
EEWSAAGFGVRLRDNDAFPARDLPACVHTVLLTADASRTPADFPSHRVLVEVTGRAQALR
AAAAGAHGLIARGHEAGGAVGELSTFVLLQQLLDEDELDLPVWACGGAGPHTAAAVVAGG
GAGVVLDTQLALLAEAEAELPAGTSALLAGLDGSETTVQDGRRVVRRRGTQAGTPAPEVG
QDVFLAARFQERWGTVHAAVRGVRDAVLDALKSAGPGLDPAKNAGASLGPDGSGGRPFGS
ELPVAQGPMTRVSDQAAFAAEVSGHGGLPFIALALSGADQTRAVLEQTREALGDAPWGVG
VLGFAAEEIKAAQLEVVREIRPSHAIIAGGRPAQAAALEEVGISTFLHVPSPGLLKQFLE
AGARKFVFEGAECGGHVGPRNSFPLWEAQLGVLGDFLAGAKNGTATELQLFFAGGVHDER
SAAMVTALAAPLSARGAAVGVLMGTAYLFTEEAVSAGAVLPLFQRQVIDAERTDLLETAP
GHATRCVHSAFTDEFAAVKEDLAARGTPGREAWEQLERLNVGRLRLASKGIERVDGGLSA
VGEDRQLAEGMFMAGEVAVLRSAVTTVAELHASVTSGAAGFLATRREALGIGEPAAEPSP
EPLDIAIVGMACMFPGAPDLATFWANVLAGEDAVTEVPATRWDAELYHDPRGAGEKTPSR
WGGFLPEIPFEPLRYGIPPASLPAIEPVQLLALEAARRALEDSGYGSRSFDRTRASVVFG
AEAGSDLSNAMTLRSVLPAYLGSLPPALDEQLPKLTEDSFPGILANVIAGRIANRLDLGG
ANYTVDAACASSLTAVDVACKELASGTSDLVLCGGADLHNGINDYLLFASAHALSPSGRS
APFDSAADGIALGEGVGCVVLKRLADAERDGDRVYAVIKGVGSASDGRALGLTAPRPEGQ
YNALTRAYRNAGISPAEVGLVEAHGTGTVVGDRTELGSLTRVFEEAGAPPGACALGSVKS
QIGHTKCAAGLAGLIKTSLALHTGVKPPTLHLTEPNPAWDAQSSPFAFHTEARPWSAAPA
ERVAGVSAFGFGGTNFHVVLRAHGDGPPPVTSAQHWPTELFTFRGADRAAAVRAASELLA
LVEADPGPYERWRLRDFALAASRRAEAATTRGTTGTASTASTASTRGARTWIAFVAGSTE
ELTTLLRRAITGEHAPKEGLFAADEDETGDVALLFPGQGSQRPGMFAELFVAFPELQRHL
RLDATTARVLFPPAAFDETGRKEQQERITDTTVAQPALGLTGLAAFQLLTRAGVRPAMAA
GHSYGELAALAAAGALTPDALLRISRERAAAILRATGEGDPGTMAAVAAGEPEVAAALTA
AGLADSVVTANRNSPRQTVISGPTEDVLTAVERLRAQGLGAKRIPVACAFHSPLVAAAGE
TFAEVLAEVPLAPTDFPVWSNRTATRYPRSPEEIRAELAAQIGSPVRFADQIEAMYEAGA
RVFVEAGPGSVLTRLVGAVLGDRPHRTVALEDGRRAGLAGFLAALAQLAVAGADIRTAWL
FQGRDAVPADARAPRPRRAAWTVDGHLIRTADGVIPAAALHPAERVPEALVTHSSPVGPM
AAATGSEALISEFLRTSREMIAAQRDVMLGYLGADPGIRPAAPAPITYTDAPVTVTALPA
DTPVTVTALPAAAPVAVAVPAGGSVLSVVLEVIGERTGYPVDMIEPDLDLEADLSVDSIK
RAEIAGELATRLGLTTTGDTDVEELTKARTAAAITALVERVTGSKDTPAPVSTPAAGPAP
TAESVLAVVLDVIGERTGYPVDMIEPDLDLEADLSVDSIKRAEIAGELATRLGLTTTGDT
DVEELTKARTAASIAALVAGARGEAAEPAGPEAGPAAPEPVVVAPKRLVMREFDLAAADP
APSSDLLIGRSFLLLGSGPVAEALTARLTAHGAHAVTAEEPPAEGEFDGLLHLVASDAPP
VLPDVFPAYQRVLAGNPRWVLAAGASAGLRGFFRSLAREYPDTVARVVEHAPGTTPEDIA
AELVAELTAPDHEPVVLRSPGTRRGLRMAEEGLGLLGSTGAGPAGDGAAEAAALGLDADS
VVLLVGGARGITARFAATLAAASRCRIELFGRTALPEGAEDPTLAAAGTAGELRSALIAS
GLRVPAEIERAIGRIQAEREVRATLRTLAALGSEVRYRSVDALDGDAVRRAVKEIHAEHG
GIDGVVYAAGVIEDKLIAEKRPRSYDRVFRTKVDGARELLSALSELPDGEGPRFAVLFGS
IAAALGNRGQSDYAAANDALETLGARWAGSGTGRRGLTVHWGPWAPTGDGNHGMVTPELM
RHYAGRGIQLIDPDEGTMSLLRELAWGPEGDTAVVYTASGW
>A0A7Z7IPM1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium simulans|TrEMBL
MTVVSYQLPNGTVPVLLSSDTPELLRGEAATLLSYAADHPEVAPQEIAGMLFRTRIARKH
RALAMVTNRDELLSGLQAIIDGGEHPAVVRTNAPAASGRLAYVFPGQGGQRPGMGRLFYD
SVPAFQAEVDRCAEAFQTQFGESPLDYLLDEHLSAQDCARTVQPALFTQMVGLAGMWRSF
GVVPNLTIGHSQGEIAAAYVSGAISLEDAVLAVGTRARAVDEFASGDYSMAVVAADRDTC
EDLLARCTGWAELSAINSPNMTGISGDRETVQGIVDALTERGAFARVIRVQYPAHTSLIN
ELGDHVRAATQRQLRRPKFLETEIACVGATLGGAITPDLPVDQYWFWNLRNTVRFDKAIA
AAVSRDIDTFVELAEHPTLQLAIQENLALLIEDNEPTTMVVGTSNRAATNLDEFTRYLAQ
LAVHDLDYSWDHLSAESDGPVPLPLADFPNTRMNETCLWLPYDEVLPHRARPASASPTAA
REPLPTTTPPRLLAEVWVRLSRRSLVPPRAIGIIDHTGACRELADALCAAAGDAGATVRV
IAAENNETRNDLNTLAILVPESPKLGPAAAAAEVAKFFGDRAWWPGVDGGITDCWLVTVG
GEAVVGNDAPPDLAHAAASAGFRSIGAKHPSVRFRHLDLPAGATSEAAATILAALHTGAE
SELAVRGGALYAKRVVDADTAVADPDRRSLESAAHVLIIGGTGKLGLEFCDHFARRGARR
ITLVSRSGETAAVAGRLASIRSATSTQIGVVQCDVGDQAAIAVLAEQHHDAPADLIIHAA
VQYSGVELEDITAEKVDEALRAKVVGISRVLATFPRTDRCRVVLCSSISATVGGRGLALY
AAANRMLDAMAYQLRSEGLDCISVQWGHWKVHLDGSGIEMLAGIGVVPMLPADALTVGMT
IPLRSNAIVASFDLDRARSVLETCGRGSLLSDLSAAQPIDAANSSGAVEVPVSARNAGRS
HRLVKLLAGAIGVDRVDTIDTTIPMVAIGLDSLQALELRRRVKLEFDHDLEVSDLLGGAS
IADVLAKLGG
>A0A654SBG7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Chrysosporum ovalisporum|TrEMBL
MTIQTQVRPSSVFVVSGGAKGITAECAIKMAQHQPCKFILLGRSELLEVEPEFAQDCFEE
AALKKRIMDNLLAQGEKPTPMSVLKTYNKIVSSREIKKTITRIRQTGAEAEYISVDVTDI
AALQQKLAGVGAITGIIHGAGNLADKLIEKKTDHDFEKVYTAKVQGLENLLACVNLQQLE
HLVLFSSVTGFYGNIGQSDYAIANEILNKSAHLIKQNYPQCHVVAINWGAWDSGMVSPEL
KKAFADRGIDVIPVDVGTQMLVNELHPAHSDTAQVVIGSPLVPQARELDSQLRTHCIRRH
MKLEINPFLYDHVIAGSPVLPATCAMSWIINSCEEIYPGYQLVNYTDFKVLKGITFNDTL
AKEHILEIEEVEKVNPQRIKVKAKILSQNSAGKIHYHFSAQLNLHREIPPAPTYEFINLN
PDYIITTTGKDFYQNGGSTLFHGSSFQEVQRVLNITSDKITTECLWTEISAKKQGQFPFR
WVNPYTTDLSMHALWIWTQHFYQEGCLPGKVEKFEQFSPTPHNEPFYVSCEIKNKTSSSA
MADFIIHDNQGKVYSRMLGAHAIIWSMKQLKS
>A0A655F6L5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MLGRDGAAGLDAGQAFADSGFNSLSAVELRNRLTAVTAVTLPATAIFDHPTPTELAQYLI
TQIDGHGSSAAAAANPAERIDALTDLFLQACDAGRDADGWKMVALASNTRERMSSPVRNN
VSKNVALLADGISDVVVICIPTLTVLSDQREYRDIANAMTGRHSVYSLTLPGFDSSDALP
QNADMIVETVSNAIIDVVGGSCRFVLSGYSSGGVLAYALCSHLSVKHQRNPLGVALIDTY
LPSQIANPSMNEGFSPNDTGKGLSREVIRVARMLNRLTATRLTAAATYAAIFQAWEPGRS
MAPVLNIVAKDRIATVENLREERINRWRTAAAEAAYSVAEVPGDHFGMMSTSSEAIATEI
HDWISGLVRGPHP
>A0A554X5S5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Tepidimonas charontis|TrEMBL
MPSSDENNAIAIIGIAFRFPGDLADDTSFWEALKQKKDLVTQVPSDRWASSELQHTKRSE
PGRSITFSAGVLSRVDEFDAEFFGISPREAAWLDPQQRLLLELSWEALENAGVPFSRLAG
TDCAVYVGISSLDYGTRGLDDLAAMSSHSMTGNTLSIAANRLSYVFDLHGPSLAVDTACS
SSLVALHLACRALQTGEASTALVGGVNLLLHPYPFVGFTKASMLSADGRCKAFDASGNGY
VRAEGGAVLLLKPLAQAMADGDDIKAVILATGVNADGARKTGITIPSRDGQAELMRNVLA
KTNLSAQDVDFVEAHGTGTMVGDPIEAAAIGAVYGQGRKTPLPIGSVKANLGHMEAASGM
AGLIKAILALQHRALPPQLHLETPNPHIDFVGLNLQPVTEYLPLEKESPLVAGVNSFGFG
GANAHVLLREYRHDEEKAYTPEVLPPLFLSARTDAALRALASRYAERLKNSSPTDYYDIA
YAAAHRRDRLEKRLALYARTPIDAAEKLAMYAQGNTPGGLVLEEQLPQSGGMAFVYSGNG
AQWVGMGLRLMGESPTFADILAELDARMQPIAGFSLLAELQANGEASRLDDTVVAQPLLF
AIQVAITRLLKAQGIEPLAVAGHSVGEVAAAWACDALDLDAAIRVIVARSRAQGETRGTG
RMAAVGLSVEAMQATLAELGGDLDITIAGINSPKNITLSGCQADLERVQSHLAPKGVFFR
LLDLDYAFHSRQMDPIRESLLASLAGLETRTTTGTVFVSTVTGDALDANQLGAEYWWRNV
REPVRFSEAIATLAKLGCRSFIEIGPHAILQRYIGECLTSIGTKGRVLPTLRKEADGWTS
IVETVLRAHLLADQPNLGSYFPQPGRRVQLPNYPWQRERHWHPRTSESLLAIERRRVHPL
LGWRIPEAAHAWENPLDPTILPWLADHQVGGAVVFPGAAYAEMALAAAREWLGGEALAFE
EMDIVSPMVFDGEHARLLRFELNERDGSFQIKSRQRLSQDAWTLHAAGRILQPGVAARSA
RIAPPSRDKAKVDQETHYRLAATLGLDYGPSFQGLRVAIVDDNCLQAELEHPADLAQDGY
LIHPTLLDVCYQSLVDFFRTDIEAGRGVALLPVKTGRLEYQRAGKPSRFRARLTRRSARS
VLADFELFDAEDNLIACVSGCRFRAAPLAHKAQEKVSRWSIDAWLHPHPAEGLKTQLPST
QVLVEALRLDMAEQAEPRSRWFKVALPLFEALVVSFAFEAFRAIAQNDGDALQRLISPSD
PYARWLGSLLQQEGLLSRREEHWQLADGSDLPAAADIWRTLAREHGDALPHLVLLGRVGR
HLPHLLLNPSERAVFLDALRRSPVVETLYQDDPAYAGMSQAVEYILRHLAGDWPVHRRLR
VLEIADGLSEVPRSLLAALPEDRLDYVLALPEAVAERQRAEYAHASNLVIATLDYGSWQL
TADTHLPDRFDVVLLRHTLHRAVSPKAALNQVRRWLAAGACLIVSERHPDWSADFLAGLA
NDWWHKAMEDEAPHSSLMPPAAWAELLRAEGFEDVRDYAEPPAEGLAEGAYLLLARAPAQ
WETALPVTEPAAWLLLTDAASSELVGHLSARLESQAQRVITAHALPQSLTGIDHVVHLRG
WAEAPDTAPRLLAEALGIVQALAAHTAKTPRLWFITRGGALASNLPATAEPNPQQAALWG
FARVVMNEYPALACTLIDLDCQDGLDRLENELLYPDGASEILLTDTGRYTLVMQEVSEDQ
SQRAAPGERFRLDFHLPGQLRNLVWLPQEEAALADEAIEVKVQATGLNFRDVMYLMGLLP
DEAVEKGFAGASLGLEFAGIVSRVGSRVRDFRPGDKVMGFGSGCFASHVITRADAVARMP
EEWSFESAATVPTVFFTVYYALKHLADLRPGERVLIHGGAGGVGIAAIQLAKYLGAEVFA
TAGSDEKRDFVRLLGADHVFDSRSLAFADNILAVTNGEGVDVVLNSLAGEAIRRNLAVLK
PFGRFLELGKRDFFENTPIGLRPFKDNISYFGIDADQLLTGRPQLAARLFREVMALFREG
ALTPLPCRVFPAERVVDAFRTMQQARHIGKVVVSLTDARPAVERPVTAAAPLQLNKDSTW
IVTGGLSGFGLESARWLAARGAGNLVLVGRRGLDTPGAREAVEDLTTKGIQVLAISCDIS
DPAAVARMVEQVRKSCPPIQGVLHAAAVFDDALVQNLDATRMEAVLAPKLLGAWHLHQAT
LGIPLEHFVLYSSITTAIGNPGQANYVAANAGLESLAVMRRHLGLPAACIGWGPIGDAGY
LTRFEAVRDSLGQRLGKPPLRTLEALNELDHLLPQGRSLAVANFDWNTLARLLPSVTRGR
FSLLNRSLKSASLSENEADFQTLIVGKSPEEVAVIVQQLVVQEVAQILAIGADRIDPTRS
LHDLGLDSLMAVELALGLEQRFGIQLPVMMLNESPTVEKVAQRIVERLLGGTDEGDSTPN
PVDAVVQGIAKQHGEAVAAEELLQITQDVRTLQKQGTRLTA
>Q08QP5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Stigmatella aurantiaca (strain DW4/3-1)|TrEMBL
MVGVACRFPGDATTPERYWQNLAAGRDAVSEVPPERWDNATWFDPDPEVAGRTYSRHGGF
LSTVDQFDAPFFGIAPRDARSMDPQHRLVLECVWEAFERAGIPPASQAGSRTGVFVGIAA
TDYGWLIQDSKGATALDAYFLTGVAPSFIAGRTAHVFGFEGPAVSIDTACSSSLVAVHLA
CSSLRLGETDTAIAAGANLLLAPMSQVMMSKVGVLSASGRCRAFDATADGFVRGEGIGVV
VLKRLADAVAAGDPVLAVIRGTAVNQDGATNGLTVPSKKAQERVIRAALDNARLHPHDVS
YVEAHGTGTALGDPIELRALGDVYGKDRPQERPLYVGSVKTNFGHTEAAAGIAAFIKVIL
ALGNEGIPPHLHFQRPSPHVDWSRLGIQIPTGMVPWSTARRIAGVSAFGASGTNAHVIVE
APPASEGAPVAVPAADSRRAELVVVSARNDAAVSAFAQAFVGHLENEPAVPLAELAASAA
GCRSHHENRIAAVAETPAELAAVLSDLARAMPRAEGARGRADPDARPRIAFVFPGQGSQW
VGMGRELLAQEPVFRGAVERCAEAFAAHVDWPLLSVLNGSAEAERIDVVQPALFAMAVGL
AALWRSWGIVPDAVIGHSMGEVAAAHVAGALSLEDAARIICRRSKLLRTVSGQGAMAVVE
LGMEEAQARLQSRAALLSVAVHNGPNSTVIAGETAALESLLRELEAASVFCRRVHVDVAS
HSPQMDALRAPLLAELAGLSPRPGTTPIYSTVTQQVLVGGELDAPYWARNLRDPVQLAPM
IDRLLGDGHTVFLEISPHPILLPILEESLARQGGGASVVGSLRRERPARRMLLQSLGELY
VRGAPVQFSALYPKPRRLRLPAYPFQRERYWITTGSRREHRTEAGGGFLGTGIESSVGGR
TALWQRWWSGDNAAFLGEHSVSGTPFVPSTLFPLLAVEAARRAGDASSQAISEFVFGAPL
ELGPSSEQGREVQLAWLVANKPGHFRVSSRRAGEAWTVHASGRVAPAAASTASETLETVR
GRLSRGVPGAELYRAMEARGIVNGPSLRPIEELFAGEGEALARLALSERAARATHGLAIH
PALFDGALQAVGAVLASSVKGSGAPLPAKIERMLVHSSPALSGWSHVRVRALSEGQWSAD
VSLWDDAGMPLAQVTGLILERQAAAHQQAAGLFRPGWEQTPLPAPETLAAQPPSERCLIV
TRSSPFGRALRDGLSPRSQDVRLCEVGGPLGPEEASGLIGGDAPAWSVLVYVPRAGIDAH
GAEAAELLSEITEDLHVLSRAAAALPSAPALTLVTETAALSQDEVGSIGPSAILQAAAGA
IGRGASPLRCVRIEWTRGASLDGVIREILERPGEDEVAWRPEGRYVARLRRPPLELPVVH
QTYTGEPCQWVAEGAGTRSAPSLRAATRRTPGPGEVEIQVRVAGLHAHQIDTVLTASDST
GDGTKTRGDGPEAATTPRLECCGTVVALGAGVNHVAMGDEVLGIARGGLASHVIASAAQL
LRRPESLTPTHAAGSALPYAAAWYALHEAGRVERGERVFIHGATNGIGLAAVQLALRAGA
EVHATAAPSQLAYLRSLGVASVATSHSLEFADAFLNTTSGRGADVVCNTLPGAAGAVATL
LARGGRLLELAPRASKATNLEDETLEQGLAHSILRRRLSYHCIDMAELAEDRPTAYRAAL
EQVLAMLGRGELASLPVHSYPLGEARQALSALASGDEAGQQLLSFEDTRTAQLTVPLPPW
TGISPEGAYLLGGDGSAISALLVHWLAKQGASEAVVVTPPSSDDGNGPSAELARAIQEAE
ASGLRVKWQHPVSLEREHWERILRPSDGEAPRWKGIFYGVSASEESLGHDWTAKVVPAHE
LALATASLGLDAFTLVSALGTTPWGNEEAIASAFCSIAEARCRAGLPALALVLAPAKTDP
SDDRTALVAELARLLDEALTTRQPQLIALPTRADEAWLDRVRSQSRFAEPVAELATAAAL
GSTKSALLAATDPQVRRAHLEELLRTQLAAVLGMDASRLHAQTQLHGLGLDSLMALELRK
RIEQALGVRLSAALLLAGGALAKLVDHLVELWERSGEPPADPSGDGNHHAEKETHA
>A0A4P7C8E5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Saccharomonospora xinjiangensis|TrEMBL
MSQTSQTEIVEALRDSLKEVKRLRKQNRKLSDEAREPIAIIGIGCRLPGGVGSPGELWDL
LESGTDALSGFPVDRGWDLAGLFDDDPDRAGTSYVREGGFLHDVAGFDAGFFGISPREAL
AMDPQQRLLLEVSWEALEHAGIDPQSLKGTGTGVFAGTNGRDYPTLLADAPDELEGHIGI
GNAGSVLSGRVSYVLGLEGPAVTVDTACSSSLVAVHLAMRALRAGECALALASGVSVMST
PEGFVSFSRQRGLAPDGRCKAFADAADGTGWGEGAGVVVLERLSDAVRNRRRILAVVRGS
AVNQDGASSGLTAPHGPSQVRVIRDALSSAGLTPSDVDVVEAHGTGTRLGDPIEAGALVE
VFGSGRRGSPLLLGSVKSNVGHTQAAAGVAGVIKMVESLRRGVVPGTLHVDAPSSRVDWS
SGAVELVTSTTEWPEVDRPRRAGVSSFGVSGTNAHVIIEQAPETPQPETGASTGNPVPLL
LSAKTGDALRAQASRLLSFLERDPTASPCQVAHALSTTRSTFDTRAVLVGDTRESLRSAL
GALRRGEPDPAVVQGDLVRGTERPVFVFPGQGSQWVGMVLGLLESSSVFAEAFGEVAGVV
EGLVDWCVVEELGGGLDRVDVVQPVLFVVLVSLARLWESCGVVPVGVVGHSQGEIAAACV
AGGLSVEDAARVVVLRSRLIAGVLAGRGGMVSVGLPVGEVVSRLPVGVGVAAVNGPSSVV
VSGDVGGLEGFVSGCERDGVRVRWVAVDYASHSEQVGLVRDELLSVLSSVVPRSSSVPFF
STVTGGWLDTAELGAEYWYRNLRETVRFSDAIETLTAQGHRSFVECSPHPVLTMAIQETS
EDAVALGTLRRDDGDLDRFLRSLGEAHTRGVEVDWSAVIGDPGGPAISLPTYAFQHERYW
PQPTTRPGDPAGLGQIAAGHPLLGATVHAADGGGRILTGSLSAATHPWLADHSVLDTVIV
PGSAFVELALRAGRELGHDRIDELTLEAPLVLEGDTAYDLQVSVTGESATSEVSIHSRPS
GAVEENWTRHASATLTHGTEPVASPEGQWPPHGAVPLAAEDLYQRLADSGIDYGPAFQGL
RAAWQLGDAEILADVQLPESEAADAGRYGLHPALLDAALHGMGLGSVFTTPEDTSSGGSV
AFSWSGVSLHASGATSVRVRLAPAGDNAVSVRIADAAGAAVASVESLVMRPVSADQLGGG
RLPRNSLFRLTWLEQPPPADAFHRIALVGPDTWNWAPWLSTGEHSGVFPTPGALADAVAA
GTAQRPDIIVTTVPGDPASSGDDVPAEVRDALADVLGTVRAWLSDDRLADTRLSVVTRRA
IPAGQETEPELPAASVWGLLRSAQSEHPDRIIVVDIEDEKSDIGLLPAAVGGAEPQLAIR
AGRLLAPRLTRVEPAEETGFGFTEHDTVLITGASGGLGRIVARHLATAHGVRHLVLLSRR
GDQAEGAGELAADLAEAGAEVTFAACDVADPAAVATVLDAIPADRPLAGVVHTAGVVDDG
LVESLGTDQVDRVLRPKADGAWNLHRLTGEVDLKAFILFSSGATTFGGPGQGAYAAANAF
LDALAVLRRARGLSATSLAWGVWSESNGMGSRLDETALARMARNGALPLSVAEGLALLDA
THGLDHAALVPVRLDLAALRELGDTLPPMVRDLVPTPARKAAAGDSATLLRTLAALGEAD
RRRELLDTVRANAAAVLGHSSASGVDPERSFLEQGFDSLTAVELRNRVTRITGARLRATL
IFDFPTPARLTEHLLEQLDLDSASVPAPSTSGTDTEDTVLDQLDRLSRALPSAVSDDDSR
RRVAARLRDLLRSCGEPSGSGGDLDTASDDELFALVDNEFERGVEIA
>A0A2K8RFH4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MANDEKLLNYLKRVTADLHQTRERLRKAETATEEPIAIVGMGCRYPGGVTTPDGLWDLVA
DGRDAIAGFPEDRGWNLENLFDADPDAVGTSYVHEGGFLAAAAEFDAEFFGISPREALAT
DPQQRLLLETAWETFENARIDPSSLADSDVGVFTGVANGDYALTVDQVPEGFEGYLGIGG
AGSIASGRISYSLGLLGPAVSLDTGCSSSLVAMHLASYALRSGECSMALAGGAMVMATPG
GFVGFSRQRGLARDGRCKSFGEGADGTNWSEGVGLLLLERLSDARRNGHEVLAVIRGTAV
NQDGASNGLTAPNGPSQERVIRQALANAGLTVADVDVVEGHGTGTALGDPIEAQALLATY
GQNRPEDQPLWLGSIKSNIGHTQAAAGAAGIIKMVQAMRHGVLPKTLHAGQPTSKVDWAS
GAVSLLTEARPWPETEHPRRAGISSFGVSGTNAHVILEQPPEAETAETEVADAGTPGLVA
TGGVVPWVLSGKTQAALRAQAERLVSHLGSGSDANAVDVGWSLATTRAALEHRAVILATD
TEGGVATARALAEGRPDPLLITGQTAANGKTVFVFPGQGAQWVGMGAQLLDTSPVFAERL
HECAEALAPYTDWSLIDVITGAPGAPSLDRVDVVQPATFAVVVSLAALWQSCGIHPDAVI
GHSQGEIAAACVAGHLTLPTAAKIITLRSQTIAHHLAGHGGMMSILTPHKQIEETLTQWQ
GKLWIAAHNSPQTTVIAGDTDALHELHAHYTEQGIRARIIPVDYASHTGHVDTIEDELHQ
ALADTTTEPGTIPWLSTVDGQWTEPHTADGDYWYRNLRQTVQFDTTIRTLADDGYRTFIE
ISPHPVLTTAIQETLETTNTPNPTITGTLRRNDDTPTRFLTHLAHLTTHGHTPNWTTLYT
HTNPHPTPLPTYPFQHHHYWLPRNTNVGDIASAGLHDPAHPLLTAAVHLPDTGGTVLTGR
LSLTTHPWLADHTVSGAILLPGAAMAELAIRAGDETATPSLEELVIEQPLALPDSGFVDI
RAVVSGPDESGRRDVRIYSCGEEGAQWTEHATGTLAQDTASPPSPTVAEWPPTGAESMAV
EGLYEQMAEGGYDYGPTFQGLRAVWTRDGEVFAEAALPEEQLETAGRFGIHPALLDAALH
ASNYCLPGEPGSRMLLPFAWNDIRLHATGATSARVHARYTEDGGLSVALVDTAGGLVASI
GSLILREVDARQLEALTSASVNDALWTVTWAEHTATTSDLRWGTVGDVSPALAAAEAPAF
ADVTEITEAEQGRPTLIVADTTAWESRDADLPTRARELTTRALDLLQRWVTLPELSETRL
AFLTRGAMAVHDSAEVTDPAAAAIWGLVRSAQSEHPGRIHLIDTDGHSDQALPSALATDQ
PQLVLRDNTLWAPRLTTAPTSTPAEPLPLDPEGTVLITGGTGTLGALTARHLIIHHGARH
LLLISRQGPDAPGAADLSTELTELGATVHITACDTADRHHLTTTLANIPPDHPLTAVIHT
AGTLDDGTLTTLTPDRLNTVFRPKIDAITHLHDLTHDHDLAAFVVYSSATGTLGTPGQAN
YAAANTYVDALIHQRHAAGLPATSLAWGLWETTSALTATMNTGDRRRTHRGGVAPLTDDE
GLALLDTALATTAHPHLVPIKISPAALRADDTARPVPPLLRHLVRRPTRRTAHTPAPVDA
SSLAQRLAVLDHAERLRHLTELVRTEAAAVLGHTTIDSIGPDQPFREVGFDSLTAVELRN
RLNTATGLRLPATVVFDYPTSAITAGYLRDELFGSTDVAPAAVTGPGADADDPVVVVGMA
CRFPGHVADPDGLWRLVADGEDGIGAFPTDRGWDLDTLFDPDPDRVGTTYVREGGFLDGA
TRFDADFFGISPREAVAMDPQQRLLLETAWETFEQAGIAPRAVRGSDTGVFAGVIYHDYG
TNAGELPEGSETYLSTGKSASVVSGRVAYALGLTGPAVTVDTACSSSLVAIHWAAKAVRE
GECSMALAGGVTVMSTPEGFVSFSHQRGLAPDGRSKSFGEGADGTTFSEGVGLVLLERLS
DARRNGHEVLGVIRGTAVNQDGASNGLTAPNGPSQQRVIRQALANAGLSPTDIDTVEAHG
TGTALGDPIEAQALLATYGQNRPADQPLWLGSLKSNIGHTQAAAGIAGAIKMIQAMRHGV
LPKTLHADEPTTKVDWSQGAVSLLTEARPWPETGHPRRAGISSFGVSGTNAHLILEQAPE
EAPAETDAGTESTGPEAPGLVATGGAVPWVLSAKNPAALRAQADRLIAHLSAHPDTDPVD
MGWSLATARTALEHRAVVLATDIDQATAALTALSEGQPHPALTTGETGTDGKTVFVFPGQ
GAQWTGMGAQLLDTSPIFAARLHECAEALAPYTDWSLIDVITCAPGAPSLDRVDVLQPTT
FALMVSLATLWQANGIHPDAVIGHSQGEIAAAHIAGHLTLPTAAKIITLRSQTIAHHLTG
HGAMMSILTTQEWAQEALAPWHGRLWIAAVNGPTSLSITGDPDALTEFGKTLSKAKVYRW
QLPGVDFAGHSGHVDTIKNQLHQALDGVTATPGHTPWMSTVNADWADPTHINADYWYRNL
RDTVHFEQGTQALLTQGYRTFIEISTHPVLTTAIQDTTETHPEARATITGTLRRDDGAAD
RVLAGLGELFAAGVPVDWAALFAGAGARRVPLPTYAFQHRHYWLEQARTPTRAETADGSL
WAAIEDGDAQSLARDLEVDAAALGTVLPALASWRRRSREDSLTDEWRYRVGWTRVAAADP
QLSGRWLVLVPAVRADSAPVRAVLDGLAARGAEVVAAEVSETSREALGDQVKSADGGAGV
VSLLSWDDRADTEHGTVSMGTLATLAAAQALRDHGVTAPLWCVTRGAVAVAGETADPAQS
AVWGFGAVLGLDHPDTFGGLVDLPAEGEGADAELPDALFAALCSPEGEDQLAVRAEGLFA
RRMLRDRDGSGSAWKPRGTVLVTGGTGGLGSHVARWLAASGADHVVLLSRQGGEAPGAAE
LVADLAGVEVTVAACDVTDRDGVAAVLAAAERTHPLTAVVHTAGAGLLSAPVTEVTAERF
AAVTGAKVRGALVLDELVGDRELDAFVLFSSGAGVWGSGGQAPYAAGNAFLDGLAARRRA
RGLAATSVAWGGWGGGLGMIDAEGGDQWRRIGILPMDPAPALRAMARAVGGGLPNVVVAD
IDWARFVPGYTMARERPLLRQLPEVAEILAADAADAPGEGASQRDVLLGRLAELTGPEQE
VFLTDLVRREAAAVLGHADADAVEPERAFKDTGFDSLTAVELRNRINAATGLQLSPTVVF
DYPKPTTLARKVRTELVPTVDATVDGAADGVAADARGREREIRRVLASVPLRRFHELGVL
DALMRIADSAANDLDGLDDLSDPGTAVAAETSAIADLDDDELVSRAMRGTTFGND
>A0A2K8QXL7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MVNVNEEKLVEYLKRVSADLHDTRLRLRAAEERHQEPIAVVSIACRFPGGVNTPEDLWRL
VADGVDAIGDFPTNRGWDLDNLYHPDPDHPGTTYVRRGGFLYDADRFDPQFFGISPREAL
ATSPQQRLLLETAWEACERAGIDPVSLKGSRTGVYAGTATTGGTTSGDLPQKGSEGYAGN
APSLLSGRVSYTLGLEGPAVTVETACSSSLVAIHLAGQALRQGECTLALAGGVTVMATPE
VFTGFSRQRGLSPDGRCKAFSASADGTGWGEGVGLMLLERLSDARRNGHRVLAVIRGSAI
NQDGASNGFAAPNGPSQQRVIRQALASARLAPSEVDAVEAHGTGTKLGDPIEADALIATY
GRDRPEDRPLWLGSLKSNIGHTQGAAGVAGVIKMVMALRHGVLPATLHAEELTPHVEWDG
GGVRPLTEPVEWPESERPRRAGVSSFGISGTNAHVIVEQAPEEDVESVSSGVGGVVPWVV
SGRSVEALRGQAAGLVERVGGGSGLSVVDVGWSLVSARSVFEHRAVVVGEGRGELLAGLE
ALAGGVSHAGVVRSGTAVVVGGVGPVLVFPGQGSQWVGMGAGLLEVSSVFAARVGECERA
LAPFVDWSLMDVLRGVEGAGDLGRVDVVQPVLWAVMVSLAAVWAGYGVRPVAVVGHSQGE
IAAAVVAGALSLEDGAKVVALRSKALRRLAGGGAMASLGVGQDRAGQLLSGLGDRAAGVG
VAAVNGPSSTVVSGPPEQVAAVVAACQAEGERARLIQVDYASHGPQVEEIRDELMRVLKG
IRPLDTSGSDTAFYSTVTGGRAVTTDLDTGYWVTNLRERVRFADAVEALLADGHRVFIEA
STHPVLTLGLQETFDEADIAAVTVPTLRRDHGGQAQLFHSLAQAFTAGVDVDWSAAFPAD
PTPRTVDLPTYAFQRQRYWATATGGVGDVGAAGLQRVEHPLLRAAVGLADGGLVLTGRVS
ATGGDGWLGDHVVAGASLVPGAALVEWALRAADEAGCGGVEELALQVPLVLPESGGLRVQ
IVVGEAAEDGRRDVRMYSRPDRDAEPGADPDWVSHAEGVLSPSSPSSPSSPSSAAEGLAG
VWPPEGAKPMDVEGFYERAVAAGYAYGPSFQGVRAVWRDGADLLAEVALPEAAGDADGFG
IHPALLDAALHPMLLAADTESAADEGMRLPFAWNGVSLWATEATTVRVRLSPRHPSPDQD
GAVGEHGLRVVVTDAMGAPVLTVDSLTMRPADPGQLRAGNGRGADGLFTLDWIPMPGLLD
VDAFDAMGWVVLGEDSLHLAEEPGLGGGGVVCHPDLEALAAALDDGAPPPAFAVTYLPAD
GDPAEAGAVARAADGLAAVGEALELVRGWLAEPRLADARLVVVTRGAVSIDGPHGEDSGD
GALNVAAAGLWGLLRSAQAEHPDRFVLLDLHQATDSAAGEVADAVVRAVRADEPQVALRT
GRPMVPRLMRARDTGGADEAESEGLTPAGLDPDGTVLITGGTGLLGGLVAEHLVRTWQVK
HLVLVSRRGPDAPGAPELAERLSDFGARVRIAAVDVTDADAVADVVAGIDSAHPLTGVIH
AAGLLDDAMVTSQTREQVARVWAAKATAAAHLHTATADLPLRMFVMFSSAAGVVGNAGQA
GYAAANAFVDALVAHRRELGLPGLSLAWGLWAQASEMTGHMGRADLTRLRGMKPLSSERG
LALLDAARRFAHPLMVAVDLDPAGVAGVDLPVVLRGLVGGRVRRRVAEGGLLGSGLVGRL
VGLDAAARLGVVVDVVRGGVAVVLGFGSLSEVRVDVAFKELGFDSLTAVELRNRLSVVTG
LRLPATLVFDYPTPLALAEYLCTRLTGETAASRAPLAVRADADDPVAIVGMTCRFPGGAN
SPEALWDLVASGKDVMGAFPTGRGWDLDGLFHPDPDHPGTSYANEGAFLYDADAFDAAFF
GINPREALATDPQQRLLLEASWEVLERAGIDPVSLKGSSTGVYAGVMYHDYAAGLNSGDA
RLEGYAMLASSGSVVSGRVAYTLGFEGPAVTVDTACSSSLVAMHLAAQALRQGECTLALA
GGVTVMATPDVFTGFSRQRGLAPDGRCKPFAAAADGTGWGEGVGVLLLERLSDAQRNGHE
VLAVIRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLSAADVDAVEAHGTGTTLGDP
IEAQALLATYGQERPAEQPLLLGSIKSNIGHTQAAAGVAGVIKMVQAMRHGLLPASLHID
EPSPHVDWESGAVRLLTEAVEWPEGERPRRAGVSSFGASGTNAHVVLEQAPSSPAEDTPV
VSSDVGTVSWVLSGRSAEALCGQAAALAERVGDASELSPVDVGWSLVSTRSVFEHRAVAL
GDDPAELLAAVEALAEGVSHPGVVRSGMAALTGGPGPVLIFPGQGSQWAGMGAELLEVSP
VFAARVAECERALSPYVDWSLTDVLRGAEGAADLGRVDVVQPVLWAVMVSLAAVWAGHGV
RPAAVVGHSQGEIAAAVVAGALSLEDGAKVVALRSKALRRLAGGGAMASLGVGQERASQL
LFDLGDQAAGVGVAAVNGPSSTVVSGPPEQVAAVVAACQEVGERARPIEVDYASHGPQVE
EIRNELTRVLEGIRPLDTSGSGTAFYSTVTGGRAVTTDLDTGYWVTNLREQVRFTDAVEA
LLVDGHRVFIEASTHPVLTLGLQETFDEADIPAVTVPTLRRDHGGQAQLLHSLAQAFTAG
VDVDWTTLYSSSPAPRVVALPTYAFQRERYWLDGHGGRAGDPADLGLVSAGHPLLGAAVE
LADGRGHVLTGRISARTHAWLGEHVVADAVLVPGAALAEWMLRAADEVGCGGVEELALQV
PLVLPESGGLRVQVVVGEAAEDGRRDVRVYSRPAGEGASATGWVCHAEGVLSPPSDRSDD
ASGLGGAWPPAGAVSLGVEGFYDRVAASGYAYGPSFQGLRAVWRDGADVYAEVVLPEAAG
EQAGFGIHPALLDAALHPALLIDQLDTDGTETIGTEPTDGRVWLPFAWNGVALWAAGATT
VRVRLSPHQETADGERALRLTVADAVGAPVLTVDSVAMRPASVDQLRAAVAPGSHATDSL
FTVEWTPLPLAAGTGEVAAGPGGVAAEAGGVAAGAGKAAPWDDGWAVLGVGGHPDPAALV
AALGDDEPVPPVVLADMTEPTRPIGEGAEEASAEALSATERALALVRGWLAEPRLVEARL
VLVTRGAVTVDGPESTTRVDLAAAAVWGLVRSAQSENPGRFVLLDSDDDFDADADTDANL
HPNATLRTAAARAMETDEPQLALRAGRALVPRLVHAGTGGAGLVGPVAQPDAWRLDTAGT
ATLENVVPVPCPEVLEPLGAGQVRVAVRAAGVNFRDVLVGLGMVPGQTGLGGEGAGVVVD
IGPEVTHVSVGDRVMGILDQSFGPLAVTDARLLAPIPDGWSFRRAAAVPVACLTAWYGLT
DLAGLRPGESVLIHAATGGVGTAAVRIARHLGAEVYATASPGKHGVLEAMGVDAAHRASS
RDLAFEGAIREATGGRGVDVVLNSLAGPFVDASLRLLNEGGRLLEMGKTDIRVPELVVAE
HPGVIYRVYDLITDAGPERIGEMLCELGELFASGALEPPSVRAWPLSRAREALRYLSQAK
HTGKLVLDVPAPVDPNGTVLITGGTGTLGGHVADHLVRAWNIRHLLLVSRGGMDAPGAEE
LVARLGELGAEARIAAVDVTDAAAVYDLVAGVDSAHPLTGVVHAAGVLDDAMVTSQTPER
LARVWGPKAMAAAHLHAATAHLRLGMFVMFSSAAGVMGSPGQANYAAANAYCDALAIHRQ
AMGLPAVSVAWGLWADASGMTGHLDEADLARMSRSGIAAMSGERALGLMDAACWHGDPRP
AAVQLDLRALSAQPADTLPALLRTLLDSGTTTRRTAATGAPAAGLVAQLTAVPAEEQHRI
LLTLVRTQAAAVLGHTDAGAVSADTPFKDLGFDSLTGVELRNRLAAATGLRLPATVVFRH
PTPSAIAAELREKLCPARPDTPAPGFGELEELETAVARLAPHDEARGRLAKRLEALLWRL
GDDAPAEATGEDHATADGGGLDSASDDELFEFIDRELPS
>A0A5B7ULQ6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MSPVQGPQSEQKLRDYLNRVTIDLRDTRRRLREAEARSHEPIAVVSMSCRFPGGVRTPEE
LWDLLVAGRDTVTGVPGDRGWDTELLTADGVPCRGAFLDGAADFDAEFFAVSPHEAVAMD
PQQRLLLQAAWEAIERAGIDPASLRASRTGVFAAAIDQGYAQLGTGAPDTVRGFLMTGNS
MSVMSGRVAYALGLEGPAVTVDTACSASLVALHQAARALRADECSLALTGGVTVMSRPSV
FTEFSRQGAMSGDGRCKPFSAAADGTGWGEGVGVLLLERLSDARRHGHPVLAVLRGSAVN
QDGASNGLTAPNGPSQQRVIQAALADAGLAAQDVDAVEAHGTGTTLGDPIEADALLATYG
RGRPAERPLWLGSLKSNIGHTQAAAGVAGVIKTVLALRHGLLPRSLHITEPTPHADWAAG
AVSLLTEARQWPATDRPRRAGVSSFGMSGTNAHVILEQAPEPPEQDPGPEPRPTREAPPA
VPCLLSGRTAAALRDQAVRLKARVAADPRARPVDIGHALATTRTAFTHRAAVTAADRDEL
LSLLTEVARDPENAAAAVTGTAEPAPGRIALVFPGQGSQWPGMGGELLDSAPEFARSMAA
CEDALAPHVDWSLRDVVRAAPGAAPLDRVDVVQPALFATMVSLAALWRSWGVVPDAVVGH
SQGEIAAAVVAGALSLADGAKVVALRSRAIAALAGDGGMVSLAVPRERADELIAPWGGRL
SVAALNGPAAVVVSGDAAALAELTARCAERAVRARTIPVDYASHSAHVERVEDEILTALA
GITPAAARIPLLSTVTGEWLDTTTMDAAYWYRNLRGTVRFAPAVRALAEQGHGVFLEVSP
HPVLTGPVQDTAEAAGAVAPVVTGTLRRDEGGLRRALTSAAELWVRGVPVRWSRVYEGRG
ARRVDLPTYPFQQRRHWLTPATPDAERRTAADPYDDWRYRVDWQPVPDPAAPALDGTWLV
LTPEGYEENGTVRALREHGAEVLTAEVTVTGDGDGDGDSDRVRLAEALTAAADGRPLAGV
LSLLGLDDRPHPRHPGLPTGTALTLALVQALGDLGGLGNAGVDAPLWCATRGAVSTGAGD
PVTAPAQAQVWGTGMVAALEHPRRWGGLVDLPEALDARAGERLCAALGGVGGEDQLAVRT
GGLYARRLVRAPRPAARPGRTWRPRGTVLLTGGTGALGPHLARWLARAGADRLVLPGRRG
ADAPGAAELTAELAAFGTTVTMPCCDLADRAQVERLLAELDAQGTPVTAVVHAAAYIALA
PLDTIPVAAYEHVVAAKAAGAAHLDALLDRELDAFVLFSSIAGVWGSGDHGAYSAANAHL
DALAQHRRGRGLTATTVDWGIWRAENPWAPPATGADADLFNLEEHGLPRIDAERALAALQ
HILDDDETLVTVADVDWAQFAPVFTSGRPSPLLTGVAEARRALAGQDGDDRAPAAAELRG
RLAALRRPADRSRLLLGLVREHAAAVLGHDSADAVPPGRAFQELGFASLTAVELRNRLTR
ATGLRLPSTLVFDHPSATALADHLGTRLLGAEEAEEAEEAARETREPVPGAADEPLAVVS
MGCRLPGGITTPDALWRLLADRGDAVTGFPTGRGWDLDALYDPDPENPGTVTTRHGGFLH
DAADFDPAFFGISPREALAMDPQQRLLLETSWEALERAGLDPQALRGSRTGVFTGVNYSD
YASAVARSTEGEGHLLTGSAPSVVSGRVAYTLGLEGPAVTVDTACSSSLVALHLAARALR
AGDCSLALVGGVAVMATPGALVSFSRQRGLAADGRCKAFGDTADGMGMSEGAGVLLVERL
SDARRHGHPVLAVLRGSAVNQDGASNGLSAPNGPSQQRVIRAALADAGLSGADVDVVEAH
GTGTTLGDPIEAQALLATYGQDRPEGRPLLVGSLKSNIGHTQALSGVAGVMKTVLALRHA
TVPATLHAEKPTTHVDWSAGDVALVTEAEEWPDTGRPRRAGVSSFGLSGTNAHVVLEQAP
EPAAPESERTRTAPALPWILSARSADALRDQAGRLLQHLTGGDGPTAAYTMTGTGTEAEG
DAGTEAGGCTPDPVDVALSLTGRTAFPHRAVLVGGHDRLLPALREWVTGAAPAVTGLADP
DARTVLMFPGQGSQWTGMARQLLDEAPEFAEALHACAAALAPHVEWSLLDVVRDGTGLDR
VDVVQPVLFAVMVSLARLWRAYGVVPDAVVGHSQGEIAAAVVAGALTLEDGAKVVALRSR
AIARLAGHGGMVSLALPAPRATDRIAAWAGRLSVAAVNGPSAVVVSGDADALDELMEACA
ADGVRARRVDVTYASHCAHMDRLEAELLSALKDVEPATADVPLYSTVTDEWLDTSRMDAR
YWYANLRRTVGFESAVRALAAAGHRTYIEVSPHPVLTPAVEETLESAGADAAVLGTLRRG
EGGTERLLRSLGEAWAHGVPVDWSPLFAGTGARRVELPTYAFQHQAYWAVPGPETGGDVT
AAGLGSTGHPLLAAAVELAETGEILLSGRISVRSHPWLADHAVSGVVLLPGAAFVDLAVR
AGDEAGCPVVEELTLQAPLVLPASGGVRLQVRVGAPDATGRRTLDVHARPEDATDAPWTA
HATGTLAEAAGQDTPAPAGSWPPAGAEPVDVGDLYARFAASGYGYGPAFQGLRTAWRRGG
DLFTEVSLGQDQHPAAAAFGIHPALLDAALQGLWLAPGTASGPDLEPGTARLPFAWTGVT
LHASGATELRVRLTQGGDGSVSLTASDPSGRPVATVTGLAVRAVDVAALRGATAPAAHDS
LYRLEWTAVPAPAPAGPVPPARWAALGPGLALPDTYPGLAGLAAAVDRGAPVPDVVLVPR
SEAAGDDATAVHTLVRDTLTLLKDWLADDRFADARLVFLTSGAVCAGPGDAVSDPAAAAL
RGLVRSAQSEHPDRFVLADAPDHDALLAVLPGALDLDEPQIAVRGEEVRVARLARVEAPE
DADEGPVPFDPDGTVLITGAGGALGGLVARHLAARHGVRRLLLAGRRGAGTPGADALLAD
LRALGAQAEFAACDVAEPDAVARLVAGVPAAHPLTAVVHAAGVLDDGVLASLTPERLDRV
LRPKVDGALALHGATRGLPLSAFVLFSSAAGVIGNAGQANYAAANGYLDALAQHRRAAGL
PAQSLAWGLWEQAGDMTGTLDATGLRRMTRGGVTALSDAQGLALFDAALRRADALLVPVR
LDAARLRAGAASGTVPPLLRGLVRAARPAATGTDATQVASLREQLAGLGAEERRERIEEV
VRARVADVLGHGGPDAIDPEQAFKDLGFDSLTAVDLRNRLNAATGLRLPATLVFDHPTPA
AAAAYVTARLAPATAPAAPRRPDGDRELQRRLAAVPVARLREAGLLDALLRLTEPGDRAP
AGADGGGADPADDPAAIREMELDGLVRMALGGGDRA
>A0A1R3U0L0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Agrobacterium sp. DSM 25558|TrEMBL
MAVEIIGRSIRAPSVSNVDEFFKLLREERFVVTTVPEERWGHARFWHPVPGIPGKAYTFA
SGIVDNINDFDPAVFGLTVREAMFMDPQQRMLLQLVWRALEDASISLPMLQKERVGVYVG
ASSLDTGNTFVEDPAAGGPYFMTGNTLSIISNRISHVFGLNGPSLTIDTACSSSLVALDQ
AVRSLQSGEIDTAIVGGVNILAHPFSFIGFSQARMLSPEGVCRAYGEDGQGYVRSEGGGV
VVLRATENSTLNNDRSYATIVATGLNSAGRTNGISLPSREMQAELLSNIYSQHQLDPNDL
AFIEGHGTGTKVGDPAELWAIGRELGRKRRDRLLVGSVKSNVGHSEPASGMFGLIKAMLS
LQHNFLPASLHAEQLNSDIDFEDLHVDVNRAGHEIPRDDKRRLAGINSFGFGGTNAHIVI
SDPAKSVNEGLSTNGPFMVSAHTESALRTLLKSYVEELQSSRTDLDQLVAASAVNRTHHK
YRFSVDSAAPESIRKCIEEHLGGSKSGLGHTGEAPAGDTKTAFVFAGNGSQWAGMAMDAY
RHDTLFAQRITEICSAFKPWLDVDLLTLLTGDTLKDEIADTRVGQALLFAIQASLSDILL
KRNIKPSHVFGHSVGEIAAAYCAGILSLEHAIAIVAVRSRHQHALAGEGQMAAVAVSAGK
AMEVAEDNSLLGIELAAVNTASSVTISGPVEEIRAYKESARKLQIPVHILDINYPFHHSL
IDREREAFFVELPPYETQSGNIAFISSVTGKVLGGNDLDALYWWNNVRDIVRFNEATATA
ISEGCNLFVEISPRSILSAYLAENSRQNGSVIAVVPTLTRPARDDNPLPHIVAAVVANGV
SPWLTDAGSARNASVVLPPLPFENETLRVPETSDGVNLFGRGQNAEKYTLLGWRTDPKSF
SWKNHIDANLFPDIAEHVVDGKSILPGSAFIEIAVTAARQLYGVPDIELMNLEIIRPLEL
QTSRLSELSTIVSPETGQIEIRSREYLSEDDWSVHAVARIRKIVKSMTGRVAFVSDTDAT
AAEIDTGEAYETARQFGLDYGPTFRLLNGVRISSSQQTLSVQLSPPAKPAHPYLSYNLNP
ISVDAAFHGLVALFSKLTGDAAGAPYIPVRFGSVRYRAAAGDIRSAQIDIQKFSPHSLKI
RVELFDASGELIAILDDCRFKRTFLKLHHSLETISYHFENVSSRPSGSGTTILPDVLSPY
ESAELGEETLLQDASVYRASYDIAAKVLESFGGLEHPLLASRHDLRSYFANCFIVLEDYG
LARFEAGRWQIAPDSGLPSFGEIIREVVAQFPASSATAILVNDNYHFALTALESLAFEGE
AARLPTHQSSEATLDHFRNGLEIARKRVDETCHLTEAYLATASQPGAIVVEIGATSVAVT
TKLAALAELYHAQLLIFEDDENLRSTLKTAFARNPHVSVIDTEEIELPSNIDLAVSASGH
IFSRLQDSDDLREAFKKIAATGAELLVVDHQYGVLADFLFGLQPGWFEQAASSDFPIGKM
LSADGMLKLVTQLGFSDASVVPADFAQGSLSVLIAKGHEGSKQEVEHPLRSLVTIGWNDA
GLLNTGVDDHVHVNIASLSDSTKIEEAVRNSPVGTVDIIYTVDKVSPSDHSQSLQNHVNI
LGLLAEALRQCFGNDAGSKPRLFIIAPGGTSSTSAEVDAVSHGVWAFARVLQNEYDEISV
VSVDIDNTLLSEGTLRQITGLQVEGENELRFDCENGTFQFLRAVPGPFRRADNLTSDYDA
ASITQKSPGRIETIIWQQNAVKSPAANEVLVEIAATGLNFRDVMWAMGMLPEEALEDGFA
GATIGMEFSGTVRSVGDNVRHLQPGDRVMGIGPDAFSTHVVVSAGGVTRIPENMGLVEAA
TLPVTFLTAYYALVDLGRLRAGETVLIHGGAGGVGLAALQIAKLTGATVIATAGTDEKRN
LLTTLGADHVFDSRSLEFFNDVVNVTDGAGVDVVINSLFQEAMERSIELVKPFGRFLELG
KRDYYADSKIGLRPFRKNISYFGVDADQLLVAAPDTTKRIFDEIARIFADNQLKPLPYRT
FAYDEISSAFRLMQSSGHIGKIIVTPPKKGKDGVLTLSRSALKFSSGVYLVVGGIGGFGL
EAANWLAENGASHIALATRSGVMDVETQNAIEQWQRIGVSTSVHACDVTNEHQLASLLED
LRQIGPMKGILHAAMVLDDALITNLTPERNRPVIHTKVEGAALLDKLTDGDDLDLFLLFS
SATTMIGNPGQSNYVAANGYLEGLACARRQRGKPALAVAFGAIADTGFLARNADVNELLS
RRIGKTAMKARDALRFVEEYLSSVSSVINGGAVVIADIDWSAAAGLPIVKKPLFSKIGSN
PLVQQGASGEQMDLYAMIDGKSVEETDEILHSLIAAELSSILQMAETNISREKVLRDIGL
DSLMAMELGTSFEQKTGIELPLNAISDGTTVGDVVVKLREKLHNRQSLDGAQGNVDELLS
GLTMKHIGSTTLADVA
>G0PRM1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MLDSATDVDGGTGCEPIAVVGVSCRLPGAATPEEFWRLLADGRSAVGQVPAGRWQEEPPE
EAARRGAFLDEVDRFDAAFFGISPREARTMDPQQRLTLELCWEALEDAGIVPETLRDRPA
GVFVGAIADDYARLLHGQGMAAVGAHSFTGLHRSLIANRVSYRLGLNGPSLTVDTGQSSS
LVAVHLAAESLRRGESEIALVGGVHLNLVPESAAAAARFGALSPTGRSHTFDDRADGFVR
GEGGAVVVLKPLDRARADGDVVHCEIRGSAVNNDGGGASLTSPSARAQTEVLRAAYRRAG
VTPERVGYVELHGTGTRVGDPVEAGALGAALSAGRPADSPLLVGSVKTNIGHLEGAAGIA
GLVKTVLSLAHRRIPPSLNFTRAHPDIPLDELRLGVVQEATPWPESTGPAFAGVSSFGMG
GTNCHVVLAATPTPTPTPTSASASERPGDRDGSGAGERADSRPVPWVLSGRSAAALRDQA
DRLRARVASEPDLRPEDIGHTLAGHRTLFDHRAVVLGDDRTARVAALTALAGAQASPDVV
TGQAVPGDSVFVFPGQGSQWTGMGLELHEEFPVFAEHLLACERALRPYVDWSLLSVLRGE
PGAPPPDRVDVVQPALFAVMTSLARLWESLGVRPAAVVGHSQGEIAAAYAARALSLEDAA
RIVAVRSRALRRLSGRGAMAVVSMPADEVERRIGGAGPVLSVAAVNGPVSTVVAGEPRAV
DRFVDRVAADGVQARRLPVDYASHSTQTEEIGEDLVRSLAGVSARPGGIPFYSTVTGEVV
DTAGLDADYWFRNLRRTVRFEETVRLLLADGYRQFVECSPHPALLAAVDDTAAAAGVPAA
STGSLRRGDGGRRRFLTSVAEAHTQGASVDWAAVLADPDGRRVRLPAYAFQRERHWWQAP
AGPVPGPVAPPSSTPPVPVPDTDEGEEQPAPAAGPRSLADRLGPLRETDRDRTMLDLVRD
GAALVLEHDSADGVDADLTFRDLGFDSMTAVEMRKRMNAVTGLRLPSTVLFEHPTPARLA
RHLWKELLPATSEAPAVPAGTVPDEDEPVAIVGIGCRFPGDVRSPEDLWRLLAEGGDAIT
EFPEDRGWRLEELFDQDPENGPRSYVRQGGFLHDATQFDAAFFGISPREADAMDPQQRLL
LETSWEALERAGIDPAGLRGSDTGVFLGATSQDYGSRLDDAPAGYEGYVLTGSTSSVASG
RVAYTLGLQGPALTVDTACSSSLVALHLARQAVSRGECTMALAGGVSVMATPGMFTEFSR
QRGLAPDGRCKPFAEAADGTAWGEGVGVLLLERLSVATREGHRVLALLRGSAVNQDGASN
GLTAPNGGAQRRVIQQALDAAGLAAADVDAVEAHGTGTTLGDPIEAQAVLATYGQDRPAD
RPVLLGSLKSNIGHTQAAAGVAGVIKMVLAMRHGMLPRTLHLDRPSSHVDWDAGAAALLP
EPAPWPTVDRPRRAGVSSFGISGTNAHVILEQAPQAPDEPEAPEAPDELEAPQAPQAPQA
SEAPEAPKAPKAPGREGADPEPGAPGRVPAAAPWPLSARDPHALRHQAQRLHDWLLDHPG
TPPADVAHTLHTGRAALTHRAVVVGADHDAFLTGLRALADGETARHLIQDAATADRRTVF
VFPGQGSQWAGMGVRLMAESPVFHEHLTDCADALQPYLTFSPLAVLRGEPDAPTLDRVDV
VQPVLFAVMVSLARSWETYGVRPDAVVGHSQGEIAAAHLAGALSLDDAARIVCRRSQALA
VLAGRGGMAALPLPLSETTELIGRWGDRLEVAAVNGPGAVVVAGDPEALAELLAVCTERR
VAARRIAVDYASHSAQVEPVRERLATELAGITPRRGDIPFHSTVTGAEITDTSTLDADYW
FHNLRQTVRFADVAGELFATGHLNFVEISPHPVLTLALQDTLEHHGDDGTTATVTGTLHR
DDAGLANLLTSLARLHVTGTPVRWDPHAANTPAHPVELPTYPFRRQRHWLTPPSSGPDLS
AAGLDTTTHPLLPTAVPLADHGGVALTGTLSLQTHPWLADHTVLGTVLLPATAFVELAVQ
AGDRTGCPDIEELVLQAPLVLPTTGTVRTQVVVGAPDADDRRPVGIHTAGNGERPAWTCH
ARGTLAPAADAASPTETAPWPPAGAEAVAVDDAYTHLDGLGFGYGPAFRGLRRLWRLGDD
LFCEVELDTALTPDAGAYGLHPALLDAALHPLVRYDDRVRLPFSWTGVRLRASAATALRV
HLGRRPDGGTRLTATDPAGGPVAEVDGLMLRPVDIGQLAAPAAEHDLYLVDWTPFAAPDL
PRAAPDRAIVDPSPHSAHPRGVDTYPGLAELARAVDDGRPVPELVSYHPGPTGTVPAASP
GHPARTHDLVTRTLGFLQDWLADDRFAEVPLAVITRSAVRTGPADGPDDPAAAAIWGLLR
SAQSEYPGRFLLLDADTDTDADAGVDAGAEADAVADAGAIDAGAVPADPTAGALTAAMAA
GESQLALRMGEIRTPRLVHRPRTGGGTPFRPAAGGTVLITGGTGTLGRLLAQHLVTRHGV
RRLLLTGRQGPDAPGAESLRAELTGLGAEVTFAACDTADRDALAALLAGIPAAHPLTAVF
HAAGVLADATLPALEATHVRTALRPKVDAAWHLHELTRHMDLTAFVLFSSVMATLGGPGQ
ANYAAANAYLDALARQRRADGLPALSLGWGQWARASGMTGHLGRADLARMRRAGIRPLPT
EEALLLLDAALAGQDSHLVPVKIDAVPSPATGMLRALAPAPARRTAAVTPPSAAEPSDGD
FRARLEALSGTERAARLLDLVRAHTAVVLGHTSPAHVDTDQSFQDAGFDSLTSVELRNRL
AALTGLRLPVTLLFDHPTPAAVAGLLHASLFPADGPLGADAPPSAETRGAGRATEPVAIV
GIGCRFPGGVSSPDDLWRMVADGVDGVGPFPADRGWDLERLYDADAGRLGHSYVRQGGFL
HDAAEFDADFFGISPREALATDPQQRLLLEVAWETLEDAGVDPAALRGSRTGVFAGLMYH
DYGSRLSASPPELEGYLGNGSAGSVASGRVAYTFGFEGPAVTVDTACSSSLVALHMAAQA
LRSDECSLALAGGVSVMSTPQTFVEFSRQRGLSADGRCKAFAAAADGFGPAEGIGLVLLE
RLSDARRNGHRVLGVLRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLSAADVDAVE
AHGTGTTLGDPIEAQALLATYGQDRPEGRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMR
HGLLPETLHVDEPSPHVDWSAGEVQLLTEPVRWRAEGRPRRAGVSSFGVSGTNAHVILEE
APAVAPLPAPPADHSGPLPWMVSGRDTAGLRGQAARLAELVRVRRAAGPVDREWLAGVAK
GLAGRAALEQRAVVVGTEVEELLAGLEELTKAERSLPARTGSGVVFVFPGQGGQWVGMGR
ELLDSWPVFADRLAVCERALDPFVDWSLREVLTGSDEKWLGRVDVVQPVLWAVMVSLAEV
WRAAGVEPDAVVGHSQGEIAAAVVAGRLSVKDGARVVALRSGALRELAGRGAMASVALDA
AEAEGALPASVTVAAVNAPGQVVVSGPPDEVAELCVRLDEQGVRARRIEVDYASHHAHVE
AIEEELRAGLEGLSSHGSDTAMWSTVTGELIDDEELDAGYWYQNLRRPVLFADVMRRLED
AGSQAFVEIGPHPVLTLAMEQTVTDGRVLHTLRRNRPETAQLLSSLGAAWAAGLPVAWRD
LLPAAEPVALPTYAFQRQRYWLDAPATTVDAQPAGLTPTDHPLLTAVAVLPGDDARLFVG
RIALHTHGWLRPYTTAGSVVVPPAVVAQMTLHAGRSVHSTRLADLTIVEPLVIPDDEAVQ
VQLLIGGPDDDGARRVDLHARPADGTDADWRSHATGLLRTHPGDEPAPVAAPWPPADAEP
IPEDVVRRALTEGGYDTEDVLARLGRLWRSGDDVLAEGHLPAGEELASDRFTHALLQAVG
ALTMEATPEPRQAARWRGFAALPGLTGDVRARATPTGPDTRALRLTGPDGTPVADVGELT
LRPPTAAQLRARRRPLHRLVWEALGAPSQPSAPGRYAVVGGEEDHLFQALRRQGADVRPC
AEPAEATAAETVLVPVEPIGTPAPGQAHTAVARLLPIVQSWLADERFADGRLVLVTRSAV
STDGGDVADLAGAAVWGLARSIQAEHPDRLVVVDIDERDESVRALPAVPATGRPQAALRA
GALFVPRLRPVPRTRPPEGREADGAPLLDPSGTVLVTGATGTLGGLVARHLVHEHGAHRL
LLVGRRGATAPGMPALVGELTEAGADVTVESCDVGDRDALAAVFDAVPVEHPLTAVIHAA
GVLDDGTVTSLTGDRFASVFRPKADAAWHLHELTRDRPALRSFVLFSSAASTLGTPGQGN
YAAANAFLDGLAHRRRALGLPATSIAWGLWAERSGMTRHLGEDDIRRIIGGGAAEMSSSE
GLALFDAALAADLPFTVAGVDTTRRVAGALPPVLWETNGAVPRTTGGTAPESETFARRLA
GLPEREREEAVLALVRRTVADVLTHADAERVDPDRAFKELGFDSLTAMELRNRLAAAIEH
RLSASLVFDFPTPRALAAHVRGELFGSAVIDPVFAHLAELHTTLSALEADEAVRHRLVAR
LQGLVAVVTDTAKHGGRPPEPETDDDSDIETATADEVFAILDQEFDDSAAPHGPQGGSAR
>G3J047|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Methylobacter tundripaludum (strain ATCC BAA-1195 / DSM 17260 / SV96)|TrEMBL
MSHEEIREDQENIAIVGIAVRMPGAPNLEAFWQNLRDGVEAVSLFSEEEMLASGLDLDTI
RHPLFVPAKAILDNVEMFDASFFGISPREAELMDPQHRLLMESAWEVLEHAGYDSETYEG
RIAVFTSAGMNTYLPFNILSNPGLLEQVGGFQLSIYNDKDFVPSRIAYSMNLKGPAVDIG
TACSSSLVSVHFACQHLITYQSDMTLVGGITIHLPQKMGHLYEEGTAYSPDSHCRPFDAD
PSGLIDGNGVATVVLKRLSDALDDGDRIYAVIKGTAINNDGASKVGYSAPSVNGQAEVIV
EAQAMAGVNPETISYVETHGTATPLGDPIEVAALTQAFRAGTDKKGYCGIGSVKSNIGHV
DKAAGLAGLIKTTLALDHGMIPPNLHFKQPNPKLNLPDSPFYVVDSLQLWPRNRQAPRRA
GISSFGVGGTNAHAIIEEAPLPTPGSPSRPVQLMVVSAKTEAALSAAAENMAAFLEREPH
INLADTCHTLQKGRRAFAHRLAFTCTTAAEAASTLRTSPHSHTDNQADRGLVFMFPGQGS
QYAGMGAELYQQEAVFREQIDLCAQILAPELGLDIRSLLFPAEADSEAAAAQLKQTALAQ
PALFTIEYALAQLWLSWGLQPRAMIGHSLGEYVAACLAGVFSPQDALTLVAARSRLMQSM
PVGAMLAVPMAEATLLTLLGELAQPLDLAAVNGPELCVVSGPLPAIEALQNQLTGQGLSP
RLLHTSHAFHSAMMEPMLAPFTDLLRRIELKPPQIPYISNLTGTWISEAEATHPEYWTQH
LRHTVRFGEGLKALLTAEPSQVLLEVGPGRTLGGLAGLVNPAPPLCLSSLPQAQEKRGAQ
SFLLRSLADLWLAGIGIDWNGFYRHERRLRVPLPTYPFQRRRYWIEPGKPAAGEAAKTTA
GARQANPADWFYLPSWKTSLAPTPQSATSAPEWLVFADELGLADALAAEQTQNGRQVFKV
NPGSGFAQPHERAYTVNPVQPADFDALLEALQQQNALPQQIVYLWGFSQSNPAATDLNRH
CDSLLALIQALGRLTVRLPIELTVVGNNMQAIGADHPIDPAKAALLGLLRTLPWEYPNLS
CRAIDIPLPATERQLHSLASRLARELSIPAQDPLVILRTGYRWLPSLEAVRPDSPRETAD
CLLRNGGVYVITGGLDGIGFLFARQVAAMVQAKLVLTTAGSLESAANAQQLQELEALGSE
VLPIQLVDYDTPSLNAVLNQAEHRFGRIDGIIHAADMSSPRPFALMQDIHKTEQDAYWQA
QQLTLNALKQSLEHRNIEFCLLMSSLAAEVGGIGQAAHAAACVYTEAFARQHNQTGAYPW
IVVHWDVWQEEGDRTDINSALAEIAMTPEEGGNAFQRLMALGESTCIIIATSDPRFRRKA
FSRLQEDQPGAQTPAAGRRHERPDLSNPYEPPRNEDEAAMAELWQEFLGIDPIGIHDNFF
DLGGHSLLATQLVTRLQQSFKVGVELVLFFTAPTIAELSEALLQKQLELSDEDQLAQWLD
KLEQMSEDEAQALLESGSLPAELLNALGH
>G0PR30|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MRDDRIAVIGTALRFPGADSPEAYWRDVRAGTGHVRRFTRAEFAAAGVPAAEYERPGFGG
ASALLTDVDGFDAGFFGMSGREAELTDPQQRLFLECCFHALEDGGYAGGEDRRTGGAVRI
GVYGSSGYRLYSLHGYLTENLAAEAGSGDWMTAKQVQVGTYPDFTATRAAFRLGLTGPAL
TVSTACSSALVSVHLACQALRAGDAELMLVGSAALHLPQVSGHVPVKGSTLSPTGTVRAF
DADADGTVGGNGAAAVLLKPLARALADGDTVHAVILGSAVTNDGADKRGFAAPGVAGQRD
AVLGALRAAGVDAASIGYVEAHGTGTLKGDPIEFAALTEAFRAHTDRTGFCALGSTKPAI
GHLDSAAGLAGLIKAVEVLRHGVVPGLVNFTRPNPALAVDDSPFLLPVRERPWPLAGVRR
AGVHSIGMGGTNAHVILEQAPETPHAASVSDTVPAPALLPLSAADGDALRAYAVLLRDRL
AGGSPPSPADLLTTTALGRRHLPHRLVVTGADPVAGLDAFLAGAPAGGAYTTGVADGVRE
RRPVFLFSGQGGGHRGMGAELAARFPVVAEVLAACARVYAEETGREDFLDRIVGGQGPER
WDTAFAQPALFALQIAQARLWERLGITPARVAGHSVGAYAALCVAGALETEDAMRLVCGR
GRLMLERAAPGAMVSAFVPRARVRELLAAVPGLELAVVNGATHQVLGGTPEAVDAARALL
AARGEAYEVLPVDRAFHTALLDPALEDFRVLADKVELRPLHTEFVDGIDGTVRPAGWRPN
AAHLVAQARRTADFAAVLDRLAGSPLLLELGPSAVLTGLVRRALPDAVCVPTRPWERAVA
ALHCGGAGVDWAALLDRCGGRRVRLPTYPFQRRSHWRGPAPYTAPAPPAPLMEQPAPIGG
AAPSPTRSTEDRMTEQAVLDRVLELTARHLGHRPDEVGADRTFVGLGADSLQLIGMVRQL
EAEFGTEISMREVLEEAGTPRLTAALIAGRAAPATLPVAVDPARVAREQASVTVRPASVT
GEPAQVTVRPAATGGTDTTVYATRAEVAALSEQLRQLAETQAAMITQLTEAVALLTARTT
GKDGR
>A0A292G5C9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Bifidobacterium bifidum|TrEMBL
MKAVFAATINNADPLAALEVGELPEPQPRPFWSTVSVKAATVNHHDIWSLKGVGLAAEAT
PMILGTDAAGVLDEDIPVRKGLKAGDEVVLYTVIGADGAGVMPGERRTILSERYPGTMAA
KTQVPSANVFAKPANLTLDEAAALGTSWLTAYSLVFASAGVKPGDTILIQGAGGGVSTAA
VQLAHAAGLEVFVTSRDETKRERALALGADAAFEAGARLPRKVDAVIESVGAATWGHSVR
SVRPGGTIAICGATTGDQPGAELTRVFFQDIRVQGNTMGSREDFARLLRFVEHADIHPVI
DSTFGLADARAAFAKVLSGDVFGKVVVRI
>H1KFY8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Methylorubrum extorquens DSM 13060|TrEMBL
MRTAAAITSESAPPVAIVGMHGRFPGAADTPAFWSNLVAGKDVVGEIPGDRWNWRRLHGE
KSAEGETSYSRWGGFTEHVDCFDAGFFGILPREADSMDPQQRLFLQTAHSAFEDAGFAAR
DLAGRKVGVFVGVGNADYPVLMRGDRVPVDAYRGTGMALTAIPNRVSFQFDLRGPSSAVD
TACSGSLVALHRAVASLRDGECELALVGGVNLLLGPELYVAFSKAEMLSPTGRCRTFDAG
ADGYVRGEGVAALVLRPIAAALADGDYVYGLIRGSAENHGGRAHSFTAPNPDAQAEVIRD
AWTRAGLPLGNAAFIEAHGTGTPLGDPIEIDGIKKALALSGGSDRPNGVLPIYISSLKSH
IGHLEAAAGIAAVIKAVLSLQRSELPGNQHFEHLNPQIEIGNSPLAIPEKNVPLQTRGVP
LCAGVSSFGFGGVNAHVVLEGVASAAQRDADGEGRPFLILLSARDESGLRARAAQLLDVV
QYAEGTARQRRLELELYDALAIPRTPDAAPAGLAANAVSPTKLTRALEQLSTTAGRGLTI
ADVRDCVTVEEVAERIARRPSSFALRDLSRLISGTALPESAKRSISVPSIARSLMLGREP
MSERLAFVVRSLSDLIKRLESFLADADGEWKRFTLRGRGEKLVPPVTSSGHPSEHHLMRW
AEYWGLVKAPQTPWAGIYPDFPLPAKTPLPAYPFELKRIWFRSTAPAPAAESEDQGRKSR
SNVMHLHEGGLEAREGRRLLPISVAWRECWGASTVGLPSSLVALPVLAEHLERSGSRAGA
ADRIGLGRPCDLQAGATARKSGDGEKAVIHCIAEGPTTGALLEARAASVAPGFIPQPSAE
CTGTVDGSEFYRMLERAGFQPDARYRCVRRVAIGRGHLGFEVDLHRTAAEDGRFWTALIS
TVVLGIGWLLDPALSPSGFGMIWRIGLLRFDADAYDHVVRIDIAQTEDGTISVWARNDRS
EPALGLTDVLTRNFSLAPVGRTELRSRAAGAGR
>F8B3X3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Candidatus Frankia datiscae|TrEMBL
MSHAETPSDIAVVGLAARLPQAVGPGEFWQLLENARSAVTDVPAGRWEGIPDDIRPLRGG
FLDGVADFDPEFFGISPREADAMDPQQRLVLELGWEALEDARVVPAALADTRTGVFVGAI
ASDYAGLVHRYGLNAVTRHTLTGLARGIIANRLSYLLGLRGPSLTVDTAQSSSLVAVHLA
CESLRSGESELALAAGVHLNLTAETAVSAQRFGGLSPDGQCFTFDARANGFVHGEGGAVV
VLKPLAAALADGDRIHAVIRGSAVNSGGATAGLTVPSAQAQRDVVRAAASRAGVDPRDVR
YVELHGTATAVGDPIEASALGAAYGVGRPADDPLLVGSVKTNIGHLEGAGGIIGLVKTVL
AITHRVLPPSLNFVTPNPRIPFEELRLRVVTARRPWPHDDRPLLAGVSSWGVGGTNCHVV
LGEAPSARPTAAGAAGAAGAAGAAGGSGAAEASSVPPARAGGDREPAAHADGGREPAVRG
VVPWVLSGRGVDAVDTQAGRLLALLTDPPAGGTGSSVENAESGDGGADGNSTGGGGDPAD
IALSLATTRARFEDRAVVIGADRAELSVGLRALVAVEPAAGVVRGSVGERGRTVFVFPGQ
GSQWAGMAAELLDTSPVFARSIEACAAALTPHVDWSLPDVLRDAPGAPSLERVDVVQPAL
FAVMVSLAAVWRAFGVEPDAVIGSSQGEIAAAHVAGALTLEQAAAVVALRSRALVDITGR
GGLVSVPLPAAEVATLLTPWADRAGIGVINGPDATVVSGETGALDEFVATLTAAGVDVRR
IPVEYASHSPQVIPVRERLLELLDGITPVAADVAFYSTVTAGRLPTTELTPAYWYRNLRE
TVDVDRAVRAALAAGHGTFVEMTPHPVLTGAIQRIAADAGPGHADTLVTGTLRRHDGGPR
RLLASLAEAYVRGVDVDWAAAIDPAARVTDLPTYPFQRRRFWLGGAAARPAPPTATPATD
LPDVSIPAQIFPDHDTATHGTDVAVPAAPRTSSPAGPSRLARRLDGLTPRERDAVLLDLV
RAAVGTVLGHTDPAAVSTGRTFKNLGLDSIAAVQFRGLLAATTGLPLTPTLTFDHPTPAA
LRDHRRPR
>B2J0F8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MVNMQTSDNQDPIDGVAIIGMVGRFPGAGNVDEFWRNLCEGLESTTFFQDEELDPSIDPN
LCKDPSYVKARGIIPGGETFDAAFFGINPMEAVVMDPQARVFLELVYEALENAGYESESF
DGLIGLYAGCGQNTYFANHISGRMEIVDRIGEFQTMLANEKDFLTTRAAYKLNLKGPAVS
VNTACSTSLVAIIQACQALSSYQCDMALAGGVSMTTPQNSGYIAQEGSMLSGDGHCRPFD
ASAQGTMFNNGAGIVVLKRLEDALNEGDRIYAVIRGSGINNDGADKVSFTAPSVDGQAEA
IAMAQAYANFHPETISYIEAHGTATPLGDPIEIEALTQAFRVHTDAKQFCAIGSLKSNVG
HLVAAAGVAGLIKTVLALHYKKIPPSLNFEAPNPKIDFANSPFYVNTKLAEWSQGETPRR
AGVSSFGVGGTNAHIVLEEAPQIQNSGSSRPQQLLLLSAKTSTALEAATANLQQYLQYNA
EINLADVAYTLQRGRKALNYRRSVVCHDITDAIAALQSLDPNQINTRHTVIRNLAVAFMF
PGQGSQYVDMGLNLYNREPVFQEVVDECAEILKPLLGGDLRRIIYPAPSDRETAAIALKQ
TCFTQPALFVIEYALAQLWQSWGVKPQAMIGHSIGEFVAACIAGVFTLEDALMLVANRGR
FMWELPQGAMLSVRLPAQEVEPRLIPELAIAAINAPSLCVVSGPTEAIAALQKQLESEEV
VCRPLHTSHAFHSPMMDDIIAPFAEVVRKVKLSPPQIPFVSTVTGDWITAQQATDPMYWA
THLRQTVRFAEGIQTLWQQPERVLLEVGPRITTTTLARQQAKDIKQQIAIASLSDNAENE
AEWTALLKAVGQLWLAGVSIDWSNFYQRETRQRISLPTYPFERQRFWIDPLPHPNRAATP
KPLNPQLEKTQDMTKSPQQKLIPLLKEIIEETSGLEIASVDDSTTFLEMGLDSLSLTQVG
LALKKKFQVKVTLRQLLEIYPNLGTLADFINPALSPETLSALGLTETVAEPIPEVPLPAP
ATTSPTLVVHEVHTNGSAPQISPQPAASSFFENVINQQLQIMSQQLSLLGNNSQAVTIPV
VPAATPQNNGVKPQNAVSIPATQTSKESPASVDTESNGAKKAFGAAARIEKTQTKTLTTQ
QRTHLDKIIQRYTQRTKKSKEYTQSHRPYLADPRTVSGFNPTMKEMVYPIVASRSSGSKL
WDLDGNEYVDLSNGFGLNLFGWSPPFITEAIEAQLKLGMEIGPQTPLVGEVAKLMCELTN
FDRAAFCNTGSEAVLGAMRMARTITGRNLIAIFSGAYHGILDEVIVRGTKKLRSIPAAPG
IPPEMVENILVVDYDSPESLEILRSRADELAAVMVESVQSRRPEYQPKEFLQQLRDFTEE
AGIALIFDEIVTGFRIHPGGAQAHFGIKADIATYGKIVGGGLPIGVIAGKSQYMDALDGG
FWQFGDDSVPEVGVTYFAGTFVRHPLALAAAKAVLQHLKQSGPSLQQNLNARTDKFVAEL
MGYFQKVQAPFTAYNFGSLFIVKSAPEFPYGDLLFYLLRDKGVHTWDHRPCFLTTAHSEA
DLAFVMAAFKESIAEMQSAGFLSAPPIEVTNSEVTNNSLRNRPPQPNAKLGRDPQGNPAW
YIPDTERPGKYLQVASVS
>B2J0Z2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MKNDNLQQNQIGDLDIAIIGMSGRFPQAKNLDIFWQNLQKGLESISFFSNQELEALGVDP
TTLNDPNYVKANAVLEDIELFDASFFDYSPKTAEIIDPQHRLFLETAWEALESAGYDSKT
YKGRISVYGSASISSYFLFNLFSNSELIKLVGLDQIRHHNRTDNLTTRVAYKLDLKGSAI
TIQTGCSSSLVAVHLACQSLIDRECDLVLAGGVSVTTLQKTGYSYQEGGILSPDGHCRAF
DAKAQGTVGGNGVGIVILKRLADAIADGDYIHAVIKGSAINNDGSAKIGYTAPSIDGQAK
VIAEALAISRIEPDMVSYVEAHGTGTVLGDPIEIAALTKSFRARTQKKNFCAIGSVKTNI
GHLDTASGVASLIKTVLALKHKQIPPSLHFEQPNPQIDFANNPFYVNDKLSEWKSNGHPR
RAGVSSFGIGGTNAHVILEEAPVREQGEHTSTTLSNRGRQGRKYQLLVLSAKTESALQAA
TANLANHLKQHPDLNLADVAYTLGIGRRAFVHRRMVVCQDIEDAIKVLEAKDPQRVLTHY
QEPGELEVVFMFPGQGSQSVAMGRELYQTEPIFREQVDDCCEQLKHILELDLRTILYPCE
EQTQWATEQLTQTHITQPALFVVEYALAQLWLAKGVCPSAMIGHSIGEYVAACLAGVFSL
EDALMLVAKRGQLMQQLPSGAMLAVALPERKVIPILGAKLCIAAINAPERCVVSGLSSEI
EDLQNCLTQQGVDCRLLRTSHAFHSQMMDSIIEPFKSLLAKVNLNPPKIPFLSNVTGTWI
TTKEATDNSYWVKHLRSSVRFADGISELCKQPNRIFLEVGFGCTLSTLTKQQSQGQLVLC
SIGHPHNQQSDVAFLLNTLGNLWLYGIQVDWSSLYAHEKRYRLPLPTYPFERKRYWVEST
KVNELNQLQNKQINHLEDESQDLFFDSHQNNILKLGSRGEKYDNFLQKIVNKQIAVMFQQ
LDILEKDM
>K9PSW7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Calothrix sp. PCC 7507|TrEMBL
MLEQHPPSSKIAIIGMDAFFGECKSLDAFERSIYDGKQHFIPLPPKRWHGIEAQEHILKE
YNLPDNKPPLGAYITDFEIDTLAYKIPPNEIEKLNPQQLLLLTVADRALKDAKIPEGGNV
AVIIAAETEMSVHQLQQRWDLSWQIKDGLNAAEIALPEEKITQLETIVKDSVHHQVDIGE
YLSYISNIMASRISSLWNFTGPAFSLTAVETSVFKALEVAQMLLTTGEVDAVVVGAVDLA
GGVENVLLRNQEAKINTGVNTLSFDQKADGWTVGEGAGAVVLQRYDSAKQNGQPIYAVID
AISIGQAHSTSLDASTINQVCQQAFQIAGIQPSEVNYVEVVGSGIPQQDTAEITGMLQAY
PAVGDGLHCAIGSVKANIGHTYVASGIASLIKTALCLYHNYIPATPNWTGVKTPQIWEGS
PFFVATESRPWFLGKDSTKRIAAVNGIGCDGTYAHLILSDEPDQKEHNSKYLQQRPFYLF
PIAANEQSELEKLLDSLQESIENSASLSDTASSYFVQFQQHSTAKYALAITGRNQKELLK
EIASARKGVNTAFERGTDWQTPIGSYFTAKPLGKQGSVAYVYPAAVNSYVGIGRTLFRLF
PNVQDDPFVKSLYKRVSDVEKLVFPRSLSKLTTRQLETLEKKLLDDSLAMFEAEMFFTRL
ITTVIRDNFQVKPKYVFGYSLGETSMMVAQGVWSNFYAGSNSFNSSALFGDRLSGPKNAV
REYWGLPPASDSSDNNFWCNYVLMASPSQVRECLKNETRVYLTQINTPEEVLIAGEPAAC
QRVIQTLGCNAFPAPFDHVIHCETMRSEYGELVKLNTLPSQNIPGIVFYSAAEYQALSLD
SNLIAHSIATGLCQQLDFPRLVNRVYGDGVKIFIEAGAGSVCSRWIDKILEGQEHITVSL
NRRGMDDHTSIIKALGKLLSHRVDLDLSSLYNLSQESSHQSKLTLRKITLGGDSITATIL
SDDNRQAFQNVATKRQHQNIPSTRESEIINSLPNSTNSILAHNLVAHNKQQEEIKMKDII
EHGLSQTEQLQSFEKTATKQQIPQPNVLAQEFSNDISTVDLNPSQYQKLNANNSRVTKAH
IAFLQTRQDFSQKMSEIIQLQLACAENLLNEES
>F1TIW4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
MQQKVDKILKGLESGQITPEEAYSYIYENEKYKDTDKSENNKDIAIIGFACRFPDAESSD
KLWLNIIKGSAAIKNIPEDRWKLDEELKKRGVKPFASMCRYGGFIDGVDLFDANFFEITE
EEAVAMDPQHRLLLEAVMEGIEYSGYSREGLWGSRTGIFIGARGGDYKQGFDNNYQNARA
ALTGTLGNFNSARISNFFNFKGPSLVFDTACSSSLVSTHYACKSILNHECDMAVAGGVHL
CINADTFISLNLMPRSLASNGVSYTFDKRADGFVPGEGVGVVILKSLTKAVEDGDTVYAV
IKGSAVNNDGNTIGVTTPDLDAQQEVVEMALKAASVDAATISYIEAHGTGTMIGDPIEIR
AIDKAFKKYTDNKSFCALGTVKPNIGHLDTAAGIASIIKVVLSLYNKKIPPTLNIEMPNP
RINFVDSPFYPAAYLSDWNPVGGVRRAGISSFGFGGTNCHMILEEAPAQVKSTEEFEDRK
EQLFLLSAKSQEALKKLAENYSVYLSKNTQLKLGDICFTAGTSRTSFKNRLAVLCSSTSE
LSQKLGSMEVLTGDGLAASHKVAFMFTGQGAQYSGMALELYENQPIF
>F1TC78|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
MEAVKDYILKQVAAKSLSREDAVKLLQELKPKVDKSDGGVAVIGLACNFPGGNGAERFWS
NMVNGVDCIGNLPEERKKDNLELLSNPIYRKLFLNTDFSEEDINQGNIDFAKGGYLDEID
KFDADFFGIPPAEARFIDPIQRVFLETAWEAIEDAGYGGNKIYGTNTSVFVGRDNTGGSI
YKIFTQQDQMHLTGSWTGILASRLSYLFNLKGAATVIDTACSSGAVAIHEACRAIRNREC
DFAVAGGIQVNTQLTVKGQQTAMEMVESADSKVRTFDRNADGTVWGEGVGVLLLKTLSKA
IDDRDHIYAVIKGSAINNDGASNGITAPNAQAQEEVIVQAWRNAQVNPETISYIEAHGTG
TVLGDPIEIKGLSNAFGRFTNRKQFCGIGSVKTNIGHLVGASGVASVIKVIMSLKNGVIP
GNINFSEPNPYISFEDTPFYVNDRRQIWENEAFPKRVGVSSFGFSGTNCHIVLEEAPRIN
QPDKGEGTEINIFTISAKSENALKTYVHKYAEYLESESSGDIKDMCYTSQVGRGHYEWRI
ALLIRDMEDLKGKISCINKNGFEVAKVPWLYFGRHHVIAGGKTKRAVHDISEEQKNALSI
KSDSLILAMLQKEVKDKNTAMDLCSLYVNGAEVDWDSLYSGQLCKKVSLPGYPLERVRFW
APHRYMSLEGMKQKDSALQGQQKEEESESSLEVSIKGRTTGEKYSDTEKLLAAIFAGALE
IQEIDIEEDFFEMGGNSLIFIKIQTLAEKNNIKIDQSDINTYSTVKELSLYVDNKIKTNG
EGKNVNRV
>D9UBV2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces pristinaespiralis|TrEMBL
MTKEPQMTSQSVLSVPRLGEGIVEVRIVRLLKQPGDTVAKDEVVYEMEHDKAAVEIESPT
AGTLDTWLVAEGDTVAIGAPVARITPAPAQPAPPTRTEAASASASAAGSASGSGPAAEPA
AGASAHGVPGRPQPAGTRRIPPRTRAHARRLGIDEATLPSIPAAGTSLMPADLERHLAAT
TTTPPHETAPAPDTAATPHETAPAPPAPGTTDTGEAVQGVGPAGGGFVDVEQSRRQRELN
RALRASRDAVVPAAVAAVVAEDVLERARRAHQGAGFATVFQAFAHIAAHTAATAPALRSR
RLDERRLRVHDHVDLGIACATDDGDLTTAVVRAADTLDPATFDERYAQAVEDALAGTSRA
DSRVTLILSHLGGTGATLAVPVVVPPAVATLFLGAVEDTGTTPVRRMVLAFDHTVLNGSD
AAAYLDALHDALVRAAAPARPDTPAAARPAADRAEVTDRLTALAAGILGHPVDAERPLGE
QGLDSARALRLVRDIRTAFGTDLPATAVWRHPTLRALAAVLPAPTGTTPEPAPEPAPVPA
PVPAPVPAPVPAPVPGPVQAAVPAPGPAPADTVHGPAGGDDDVAVIGMAVRVPGADDVDA
FWSLLAAGECRIDDVPPGRLAGAVPEGLRAALLEGTDLFDAAFFDMTPRQAASMDPQQRA
LLELSWHALEHAGLDPDSLAGTGVGVYAAACSYDYREQLVQHETAADGYATTGTFPAFLA
NRVSHLYDFTGPSITLDTACSGALTALTLADAAIRAGTCEIALAGAANLISNGFNARAYR
TAGMLSPNGTSKVFDQGADGFVRGEGAGWIVLKSLRRAVADGDPVLAVVRAGAVNHGGRA
ASLTAPSPKAQSDLIRGALRTAGLGAADLGFLEAHGTGTPLGDPIELDAVREVFAHDPQG
MPRRAAGPGGRLWVGSAKANIGHLEGASGLAGLVKAVQVLRHELIPATPGFTRLNPHIAL
EDTPLAVAEHAVPWPAEPGRPRRAAVSAFGFGGSNAHVVLEEAPPATRPARPGDPGAAPR
NAPQTVPLSAATPTALARLADSIARLAAREDAPPLDALAWTLQSGRRHFAHRAAFTVTDL
AQLAEQAHRFAADGHRPRPADPRLRDWLDGSDLTPADWAALRPDGPAPRRVPLVPYPFER
QSYWLPTPVPRPAAPAAPAAQPGAGPDDAPGRPRYTLHDGHPLTRHRVGGRTVLPGAALI
DALADGGPVALSRLRLLRPVPVPAGSAVHLTCRTTPDGATTRLHLEHDGGICATAVPAAA
PAAAPRPADLADGPGHDVDLDAVLARNTVEVGPVYRLLHEVRRTGARVSARITAPADTDP
RTRRVAWLDAALQASCALLDGEGPRVAAAADHIEWSGRIPPTAQLTVHRVAAGPTHAVLD
LQATDPDGTPVLRVTGLRLHPAAPHPAGTAAAGASDRAAATREATPAGSELPDAAHEQAV
ADAVASLRVLVPEWDTPAPPAAVSATPVPAPQPSAPGVPDGDGVRLLSPQWMPEPSAAPD
EDPGGPLLLVHDDTSAPLADLADPGAGGGAVRCALSGGRLDADAFTRALHHAGGRPPRIA
LLVDGSSWSEDRAGALALRGWLEALLTVGQVLARHNSPAQVTLVTTRLAAPVSGAPQPGA
ALQGALLGALRTLPREAGHLTCAAVDLDTAPTPGDLAAALREPCADTVALTALRDGRRLR
QVYTEQAPPAATRREGFVHGGSYVLFGGTGGIGAAVARHLAAHYGARLLLVGRSPAGEDT
RALLAELTAQGGHARYRSADITRDDDIARVLADCHDAYGRLDGIVHSIGSVSAAPLHELT
AHDLDEVLATKVHAVLTLARALRAHQQTPGTPPCALVLFSSVAGLFGSAGGLNYAAANAF
LGHYAAATDHAGPTVRAFDWGLWRDTGLARRYSAHVRREYPGLTDFDPERGVAALEAGMS
GNRPQIVAVAGDPQPLRPLTAPPATPASATPASASVSAVSGPADNVTAAADDAAHRLEDY
AGGALAHRMSELGLTPALAADPATTVHSAAQLLAAVPEHRLLLAAVLDLLAGRHRAGRPV
PRPAELARTRRALLADHPDLAGHLTLLDRALESYGPVLRGEVPATAVLFPGGDLGPVSAV
YSGNRLFDPVNTAAAHALADAARTVPAGARILEIGAGVGGTTAAALDALDARGVTRFDYV
YTDLSPAFLQHGRRRFGDRITPRLLDIEKNPGTQGLAEHTFDLVVASNVLHATRDLSRTL
AHIEELLAPGGRLLLVEMVAPAAVYTLTFGLTDGWWRYVDTDRRMPHGPLLDVARWRSLL
TARGWSLTDTDHLRDAPGCVALLTCRPPAAGADRTEEIAEGLRRIVRDLLGDPSATVPGY
LPWQELGIDSLLNMELVQAVSRSHGPLTATALFEHRTVDDLARMLARRTAPDTPTHHTPN
RPGTHPGDDTRRDDTRRGEDTAGTVAQLLALVAELTAQDPALLDADSDFPALGVDSLLHE
ELTQRLREMFPDRPVPATLIFEHPTPRALARHLAPTPTAPAAPPAGSRATAPPAPPAPPA
AAGVSAPARLPAAPLTAAPAAVPPAPPAGAPAAAPGAAIAVVGLAGRYPGAQDLDAFWEL
LSSGRTPVREVPAERWALAHRPHRSGGGYARYGCFLDDIDTFDAALFRITPRDAALMDPQ
ERLFLEVAREAFEHAGYARPSLTGHHGGPRVGVFAGVTANSHLLAQHDARTAGADNPEYA
VTAAASVANRVSHAFDLSGPSLSVDTMCSSSLTALHLACRALRDGEADLALAGGVNLYLH
PDRFAGLCALGMPSRGDRTRSFGAGGDGFVPGEGAGAVVLKRLDRAEADGDTIHAVIRGT
GLNHGGGTGGYTVPNPRAQAALIDATLKDAGLEAAGIGYLEAHGTGTELGDPVELRALAL
AFEDSRPAREPLRIGSVKSNIGHTEAAAGIAGLTKAILQLRHHRFVPTIGADRLNPKLDL
DNTPLHIQRATEPWSGDRPRRCAVSSFGAGGAGAHAVLEEYRMPPPAGTGAPLPVLVPLA
APDADRLRTVARRLADTVDDATATLADIAHTLATGRDPGPHRAAVTAHDHAELRAALRAL
AEDTPHPALTTADHPGPDTGDHPHAHDDDDGGRGAARAWVAHGTYRAPTGPARRVPLPPT
PFARIPCTVPGAGRPAAERPSHMPLTDTVRVPAARTVTARLGGASRWVRDHIVDEQMLLP
GAFHPELVHEALIAADENPYRTDIRDLAWPRPATGLPMTVTTHLEEPDTHGTRRFTTTVA
GTLVAQGTTHPRPADGAGAPLRPHLVYRPADLDARLDGHDTGTDAFYQAFTTHGFTYGPL
YRTVRRTAVHGEETTAELRLPPGEDTDGRHVLHPALLDGACQSAAYLLLTETPAPRRLRP
LTIGRLTVHRPATTGAYVHTRRVRRDETAGVHVFDLCLIDPDNGEVLAEIDGFRIRVDTT
AVPAALTAHPEPATAPAHPADVPLAGYRLGWHTAPIGDDTRAGTDGPLWLIGDGSGTLAA
HAPGHIPAAALLEPGPGLDEQQLERTAARTGTPATVLIDLTHLTDPHHPGLGTTPLRLEQ
TPAAWEHFTTTALTPLFTLLRTLVRSRALDGARILLVTRTAPDGHLTPLVRALHSLMRTA
AGETGRFTLRLATLDAAWALADPDAARTALLAETAADDADWTRLGPAGRRRTAVLTRTPE
PAPGTAGTLLDGAGTYLITGGLGGLGRHIAAGILHRAPTARLVLIGRSEPDDAALETLRR
AAAGDDRIIYRRCDATDPRQVADLATHLADSRIRLHGVVHAAGVLRDQFLRGKTPEAVQA
VCRSKILGALHLDAALADHPLDFFVLASSLASLVGNQGQSDYAFANGFLDQFAHQRARWA
ARGLRPGRTLTVGWPVLADAGTAPAPDTLRYLEQTYGLAPVATRDAVAALWPRLTAATTP
DTAYIALVAGDHTVWDRALPTTTTVIETAPTAPAPAPAPAAPAATPAQDTAPARAALRWL
GERVAEAVGVRPETIDPQAPLTDYGVDSISLMRLSRMLEDDLGRIPLSVLLDSATLQELT
DRLLADMGPQLTAAVTAATTPAAGPVPATAATPDATTAAAPVTAAGPHTPATATVPVPVE
AGVDDDRTAVLPDRLAGMWAADQGAAPHAPYNISLAWRLPATADREALRDAVAALVRRHP
VLGCRVRPHDGAPAFLPAPDTTALATRIVAEDTIGQAVRDEADRRIDTSAGPLLRAVLWE
PQDGGQGPVLQLTTHHIAVDGRSAELLRDDLAALYTAAAHGGPAPAPAAPFARALRREQE
TGAPGALQEDERYWTQRLAGAAPQGVLFPGGGGRAGAAGGHREYRMPPALSQHLAQVAQS
AGVPPFTVLLAAFAAALSRATGHRSFLVAVPTYGRTSREEETSVGCFVSTVPLRIDLDPG
RPVTDWLKDLNQEVRGALGHARLPYPRLVELCRAAGGEDAVPTVTLAYQNWERTGDAPTP
DGWEPVYRRGQRGHFDLGLEVTDTPAGTEILANHRTAVLDTARVDAFVEDLRRTAAELAR
RPATVGELLDPAAGTLVTRFAATVRRHGRATAVEDAHGSLSYAELDALSDDIAHRVSRLA
APGAPVAVLMHRSMRLPAVLLGILKSGRPYVPLDDSYPSERLKLVVGDAGCEVAVADREL
TWLLPQRLRIVDPTTPATPTTPAAPAAALAGAPTGGQGREPAAAVCGPDDLAYVMFTSGS
TGRPKGVPVTHANVVHTLEAIASTVGITEDAPGRLLAVTTLCFDISVLELFLPLLTGGTV
VIAERADVVDARRLGRLIDERAVTAMQATPAGWQLLVDGGWSGRRELTALCGGEALPPNL
AAALAERTGSLWNVYGPTEATIWSTIGPVTAGGPVHLGGPIGATDLLVTDTAATREAAVG
ESGELWIGGPGVARGYWQRPQLTAERFTGHPLRPEGGGRWFRTGDLVRRDADGRLVFLGR
ADSQVKVRGHRMELGEIETVLGGHPALARVVVTVHGEGPSARLLAIAVPRAGTALPDIGA
LREYASAALPPWMLPDRLIAAEQLPLTPNRKVDRQAAARLADPTTPAPADTAPAPAAASA
PADTAPAPAAGPESVPAPAPVGRAAIADRVGALWRELLELDDVPGDRRFFDLGGNSLLLG
RLFARLDDAYPGASLELADLFARPTLDDLVGLLTARLGGDTGPAPADRPGTAPVPARPSR
RELRRAFRLGDER
>A0A7U3Z9T3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Shewanella baltica OS117|TrEMBL
MSHTPSVPNSATESKKDKRLNKRLKDMPVAIVGMASIFANSRYLNKFWDLISEKIDAITD
IPDTHWHAEDYYDADKSKADKSYCKRGGFLPEVDFNPMEFGLPPNILELTDTSQLLSLIV
AKEVLADANLPTDYDRDRIGITLGVGGGQKISQSLNSRLQYPVLKKVFKSSGLSDEDSEM
LIKKFQDQYIHWEENSFPGSLGNVIAGRIANRFDFGGMNCVVDAACAGSLAAMRMALTEL
TEGRSDMMITGGVCTDNSPSMYMSFSKTPAFTTNETIQPFDIDSKGMMIGEGIGMVALKR
LEDAERDGDRIYAVIKGVGASSDGKFKSIYAPRPEGQAKALERAYDDAGFAPHSIGLVEA
HGTGTAAGDVAEFNGLKSVFAQGNDTNQHIALGSVKSQVGHTKSTAGTAGVIKAALALHH
KVLPATINVSQPNPKLNIESSPFYLNTETRPWFQRADATPRRAGVSSFGFGGTNFHLVLE
EYKPEHSRDEQYRQRSVPQTLLFAAANKAALLSELKAALSQSVNTNANKSSAASLNAIAQ
QYPLRTLASTDARLGFVAKDIAQLQAQLNQSIAHLETNAIEVWQLPSGISYRSHALVAKN
ESKKVAALFAGQGSQYLNMGRELACHFPEMRQQVMASDKVFAHHGQTPLSNILYPIPAFD
ADAVKAQEAALTNTLFAQSAIGAISMAQYSLLTQAGFAPDMVAGHSFGELSALCAAGVIS
NEDYVELAFARGHAMAQVPSDTASKAADTGTQTDLGTMFAIILKQKNDIDALNSCLAQFD
GVKIANYNAPTQLVIAGGTEQTQLAAKAISELGFKAIALPVSGAFHTPLVGHAQKPFAKA
IDKAKFSAPSVALYANGTGQLHPTDGKAIKAEFKQHMLQSVRFSEQLQAMYDAGARVFVE
FGPKNILQKLVENTLGEHLNELCLVSMNPNPKGDSDSQLRLAAVQLAVAGVALTEVDPYQ
AITSQEIAEREAPSAMNIKLTATNHISAATKAKMAKSLATGSVTSQVQYVDRIVETVVEK
EVEKIVEKQVIVEKVVEKIIEVEANQVAAVEMKQTSPSVVQGLSNHQQQATAQLSPNTPN
ISSDALTAFFSAQSHVAQLHQQFLAIPQQYGDTFTTLMTEQAKMASQGITIPESLQRSME
MFHQHQAQTLQSHAEFMQLQSSSSQAALAMLNNAPINFTPAVASQPRVTAPAPAPVAAST
VAHNAAPVAAQAVATRPAVSTPIPPVVQTAPVAFAPAVTVQVAPAAPVLVMPEMTSVAPA
TSSLSAALVQQTMMAVVADKTGYPTEMLELGMDMEADLGIDSIKRVEILGTVQDELPGLP
ELSPEDLAECRTLGEIVDYMNSKLPAAGQVVVSTTAPTAPAANGLSAALVQQTMMAVVAD
KTGYPTEMLELGMDMEADLGIDSIKRVEILGTVQDELPGLPELSPEDLAECRTLGEIVDY
MNSKLPAAGQVVVSTTAPTAPAANGLSAALVQQTMMAVVADKTGYPTEMLELSMDMEADL
GIDSIKRVEILGTVQDELPGLPELSPEDLAECRTLGEIVDYMNSKLPAVGSVIVATHVTT
AAPAASGLSAALVQQTMMAVVADKTGYPTEMLELSMDMEADLGIDSIKRVEILGTVQDEL
PGLPELNPEDLAECRTLGEIVDYMNSKLPVVSAVAVAPAANVEATPAQVPANNGLSAEKV
QQTMMSVVADKTGYPTEMLELSMDMEADLGIDSIKRVEILGTVQDELPGLPELNPEDLAE
CRTLGEIVSYMQGKLGQNTAANVVNVAVAAEPAIDLPHDLPPHSEVVLKKLPAAAELAQK
ATQQSAQQAVTRTFAKDACIIISDDGHNAGVLAEKLHAQGLTVAVVRSPESLVASASPLN
SHIASFTLAAIDDASISAVINEIKSLGTVAGFIHLQPQHKTSADAKGLVLSCAAKASVEQ
AFLFAKHLQPFLTTAATANTDSSFISVSRIDGGFGYLNHSQIARSELNQAALAGLTKTLS
HEWPSVHCRALDIAPALDAKQLANAVIAELFATDKLLEVGVSEAGATETLARVTLVAGKA
DTRHSAANLTSADKILVTGGAKGVTFECALSLAKRSKAHFILAGRSSQQAIPAWAQGKNN
SELKAAAIAHIQSLGEKPTPKQVDALVWPVQSSLEIAAALEAFSAVGASAEYLSLDVNNP
DAIASTIVPITELSPITGIIHGAGVLADKHIQDKTLDELARVYGTKVTGISNLLAALDLD
KVKLIALFSSAAGFYGNTGQSDYAMSNDILNKAALQLAQQLPNAKVMSFDWGPWDGGMVN
PALKKMFMDRGVYVIPLKAGAELFASQLLSNTGAQLLVGTDMQGSAPHDDTSNKVQETEG
SNLKKPEADLTTDSSGPHALPNAVNPSAVKLQRTLDPKAMIFIEDHCINGNPVLPTVCAI
QWMREAAFDVLKQPVKVQSYKLLKGIIFDAVMLEKGALENGAPITLELELAPIALTDKAA
KDTDECLSGQFSALISFEGRPQYQAILVIDDAVDDAANDYLATNSKATAFDAQSLAGLSA
ITTASSLYSDGTLFHGPRLQGIESVVKFDDASLVAKVSLPHFALADCGSFVPNLAPKGSQ
AFAEDLLLQAMLVWARLKYGAASLPSSIGEFISHAPFAFGDKGYLVLEVVKHSGRALEAN
IALYHQDGRLSCEMSNAKVTISKNLNGAFLANKVAANQTAANKAIESVEAKVE
>A0A221W449|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinoalloteichus hoggarensis|TrEMBL
MVDEGKLRDYLKKVTADLRQTRQRLRQVEAGRHEPIAVVSMACRLPGGVDSPEDLWDVVA
TGRDVMSAWPEDRGFDAARFYDPDPERQGRSYVREGGFLTGAAGFDAGFFGLSPREALAM
DPQQRLLLEVSWEAVERAGLAPDSLRGSGTGVFVGSSNQGYGAGVDGAVDGVEGHLLTGS
SSAVLSGRIAYTFGFEGPAVTIDTMCSSSLVATHLAIRALRQQECSLALVGGATVMATPR
NFVEFSRQRGLAPDGRCKPFAEAADGTAWSEGVGVLLLERLSDARRNGHRVLAVLRGSAT
NQDGASNGLTAPSGPAQQRVIREALRDAGLSPAEIDAVEAHGTGTELGDPIEVQALLATY
GQHREDDRPLLLGSVKSNIGHAQAASGVAGIIKTVLSLQHATVPATLHVDRPTSHVDWAS
GRVELVTEPTAWPETGAPRRSGVSSFGGSGTNAHVIVEQAPEAEHGAGPEQAAGPETAAG
RAAASEPARPADSAHPEPLPWLLSARSAAALPAQADRLIEHVRTHEPAPLDTAFTLATAR
DAMEHRAVVVAAESAELFSAAGALAEGGADPALVTGVTGPTGRLALVFPGQGSQWVGMGR
DLLVSSPVFAARFAECAEALGEWVDFAPLAALGDEGLLSRVDVVQPLLFAVLVSLAAVWE
SFGVAPDAVVGHSQGEIAAAVVAGGLSLADGARVVCVRSRLIAQTLAGHGGMLSVALSEA
DVRTRLAGFEGVSVAAVNGPSSVVVSGDAAPLAEFAAACDADGVRVRWIPVDYASHSVQV
ERIETDLSAALAGITPRSSDVGFLSTVTGDWLDTAELTPEYWYRSLRQTVRFHPAITALV
DQGYTGFVESSPHPVLTMAIQDAVDDAGIEHALVTGTLRRDDGGPRRLYDSLAQAWTRGY
PVDWTPAFGDHARRVPLPTYAFQHDRYWLDAIRPAAAGTAPPADADFWQAVDDEDLDTLA
RDLAVAPTALAEVLPALSARRARQRRDTTLDRWRYGITWRPRTQSPRPARTGDWLLVRTE
DDADRAATLRDGLAAAGATVRELVLDAADERGREALAARLRDLDAAGATGVLSLLAADQR
PDAEHIGLTTGLTGGLGLFQALSDVGGAARLWIVTRESAATGRGDAVRNPEDAAFWGLGR
VIALEHPDRWGGLVDLPADLDAATVRSLVGILADPGAEDQFAVRDGAVFLRRLVRLPIGD
AVPPRRWTPRGTALITGGTGGLGAHTARWLARGGAEHLVLTNRRGDAAPGAAELSAELTA
LGARVTIVACDVADLAALTELVDGLTRDGEEIRTVVHTAGIGLLVPLADTSTADFAEGAR
AKLVGARNLDALFAEDTLDAFVLCSSVAGVWGSGDHGAYAAANSYVDALAEHRRARGLAG
TSIAWGIWSPDGGGMAVDIVQEQLRWRGITFMDPGLAVAGMQQALDHDEAFVAVADVDWD
RFVPVFTAARDRPLLAEVPEVRDILAADAAPVADGGQDDELVRRLRASDPAEQDWLLLDL
VRTQVAVVLGHDGPETVDTGRAFRDLGFDSLIAVELRNRLNAATGLRLPATIVFDHPTAA
ALAENLRTALLGERAAAPVAVPQAARAEVDDDPIAIVAMACRFPGDVTTPEQLWELLTEG
GDAISDFPTDRGWNVAELYDPDADRQGTSYVRTGGFLRGAGDFDPGFFGISPREALAMDP
QQRMIMEVAWETVERAGIDPHSLRGSSTGVFVGAAYQGYGNDLPELPEGAEGHLVTGTAT
SVLSGRVSYTLGLEGPAITLDTGCSASLVALHLAADAVRRGECTLALAGGVAVMYGPDGF
IGFSRQRGLARDGRCKAFGAGADGMALAEGAGLVLVERLSQARRAGRRVLGLLRGSAINQ
DGASNGLSAPNGLAQQRVIRQALANAGLASSEIDVVEAHGTGTSLGDPIEAQALLATYGR
ERPAGRPLWLGSVKSNLGHTQAASGMGGLIKMLLALRHSTLPRTLHADEPTTHVDWSAGD
IRLLTEPRPWLGEGRPRRAGISSFGVSGTNAHLVIEEPPAEADEPRRIAPPAEAIVPWPV
SGRTDPALRAQAAALLDRLAAAESSADSDSADTPDTVPTAVDVGFSLATTRASLDRRAVV
VGAGETALRDGMGLLADGGATPDVVTGTADVAGRVAFVFPGQGSQWTGMAVELLASSEVF
AARFAECAAAVEEHADFAALAALSDEDLLARVDVVQPLLFAVLVSLAEVWRAHGVEPQAV
VGHSQGEIAAAVVAGGLSVADGARIVCLRSRLIAEELAGAGGMLSLALPADDVRGRIDRF
GTRVSIAAVNGPAAVVVSGEPTALDELLAECEADGVRARRIPVDYASHSAQVERIQDRLI
AALAGISPRTGTVPFFSTVVGDWLDTAELDARYWYRGLRASVRFDTAIGALARQGFGGFV
ETSPHPVLTMAVQDTLETADLPSPTAVVGTLRRGEGGRHRLLTSLAEAWVRGLPVDWAPV
FAEFDPRAVALPTYAFQRQRFWLAAENPARRTRSGPAADGRRYRVAWQPIEAPEAAPAGA
WLLVAPAEDDVHEPLAAALRARGVDLRVLPVDGAGDRATLARRLREVDDERPLVGVLGLL
GSAEEPAEQGSATPIGLIATLTLLQALGDSGIAAPLWTLSTGAVATAPAEPLTAPLQALG
WGLGRIASREHPDRWGGMIDLPADRDEDTTDLLCAALSGVGGEDQLAVRGRGLLARRLVR
AEPAAAAVPWSPSGTVLVTGGTGSFGSRTARWLAAEGAEHLVLVSRRGAAADGAEELAAG
LRDQGVEVTLAACDVADRAALAALLDSLPGPLTAVVHAAGLVDDGVLDTLSPDRVAGVLR
AKLDAARNLHESTRHHDLDAFVLFSSLAGTLGGPGQGAYAAANAYLDALAEHRHALGLPA
TAVAWGALAGGGLVDEAAAARFRRTGMGLLEPDVALHELGRAVAGDLPVLAVADIDWPRY
GPTLTASRPDPTLHGLPEARPAAPSTAETGLAGELRALPAAERSARLLDSVRALAAVALG
YPDATAVDPDRAFRDLGFDSLTAVDLRNRVAEHTGLRLPVTLVFDHPTATALARHLEAEL
LGADAAADTAAGDVTRGAATAEADDPVVIVGIGCRFPGGVESPADLWRLVDEERDAISPL
PTDRGWALEESYHPDPDHPGTFYTTGGGFLQDAGEFDAPFFGVSPREALAIDPQQRLLLE
TSWEAFESAGIDPGGARGERVGVFVGSNYHDYASRSGQAPDGLEGYLATGSAGSVASGRI
AYLFGFEGPALTVDTACSSSLVALHLAADAVRRGECTMALAGGVTVISTLDTFVEFSRQR
ALAPDGRCKAFGAEADGAGWAEGAGMLLVERLSDARRHGHPVLAVVRGSAMNSDGASNGM
TAPSGPAQQRVIRQALTNAGVTAADVDVVEAHGTGTSLGDPIEAQALLATYGHDRPAERP
LWLGSVKSNLGHTQAASGLAGVIKMVMAFRHERLPRTLHADEPSPHIDWSSGAVRLLTES
RPWAADAKPRRAAVSSFGISGTNVHVVLEQTHEPEPVAPESTGTALGAGAPAWVLSARSA
AALRGQAARLLDVVDRHPGLDPADVAWSLATGRAQFEHRAVIAGGDPAALRALADGDVAP
GLTTGIAARGRLAFLFTGQGAQRAGMGRDLYAAAPVFAAAFDEVCARADHELARPLREVV
FADPDGEDAALLDRTEYTQIALFAVEVALFRLFESCGVRPDYLLGHSIGEIAAAHLAGVF
SLADACRLVLARGRLMQALPPGGAMVSVLAAEDEVRPLLVGREHEADLAAVNGAQSVVVS
GTVAAVDAVAAELERLGRKTRRLRVAQAFHSPLMDAVLTEFAEIAAGIDYSPPRIGVVSN
VTGALADGDDLCTPEYWVRHVRSAVRFGDGIRTLTGLGVTAFAELGPDGVLIALAQDDPD
ALPRGAAAVPTLRRDRTDREAVGAALAELHVRGVALDRAEVFGRPGARRVELPTYAFQRD
RYWLEITSKTAGESGLAPTGHPLLGSTTELAADGTVLCTGRISTQYQPWLAEHRVSGTIL
FPGTAFLELALAAGETAGAGAVEELTLRTPLVLGDGDAVRLQLVLAPADEAGRRAITVHT
RPDVGAGDWTCHATGFLGAASPTPGAQTTDWPPPGAQPVDVADLYERCAANGFDYGPMFR
GLRAAWRLGADVLAEIALPEGRESAAADFGLHPALLDAALHTIAFEDPESGGTLPFSWDD
VTLHATGASALRVRLSPTATDTVALTATDAAGLPVLTVSALRLRPLPAAELLAARPTGTD
SLYRLDWPVLPVPASTPGHWGLLSDADGADGITLPGLERFAGVAEVAAATAPPQAVFADF
SASSVAAASLPAAVRAATRRALASTQAWLAEDRLGGTPLIVLTRRACAVGSEHADPVGAA
VHGLLRTAQSEHPDRFVLLDVDTDEPSPAVIAAALASGEPQLALRGAEVRVPRLVPARTI
PSAQTARPAEPAGTGTASRPWSDRGTTLITGATGTLGRALARHLVAERGVRDLLLTSLRG
PAAPGAAGLVAELTGLGARVRLVACDAADRAALAETLATVPAEHPLTAVVHVAGVLDDGV
LTALTPERLDTALRPKVDAVVNLHELTADLDLEAFVLYSSLAGTLGGTGQGNYAAANAFL
DAFAGHRQALGLPAQSLVWGLWAEASGMTGKLDRADLARMARGGLAPMSTVEAFALFDLA
TAGDEAVLVPARLAARTSTDGVVPPALRASTPARPRSAASTAAPASGAGLAEQLAPLTTE
ERHELLVDVVRAEAARVLGIADAEDVDAERGFLDLGFDSLTAVELRNRLAVVTGLRLPAT
LLFDYPTPAALAGHLRDETAPATGGLADALVGVAALERALPALEGTSADRAELAGRLRGL
LAALDETAAGQGRVDPAIDAASDDEIFDLIDNELGIS
>A0A4R8RXF1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides salmoniphilum|TrEMBL
MESADHPIKPAPRFAIIGYAARFPGAANADEFWDVLREGRDAISEVPADRWDADEFFDPE
PGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRLMDPQHRLLLEMAWRAVEHSGIAPTD
LAETNAGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQGPSVAV
DTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSHAHMLAPDGKCKTFDA
AADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
DALKRAGVAPSDVGYLEAHGTGTSLGDPIEAQAAGAAYGIGREANDPLLIGSAKTNIGHL
EAAAGIAGVIKVVLSLENELLPQHRNFQNPSPHIPWDRLPVEIVKEATAWERNERPRIAG
VSSFGFAGTNAHVILEEAPEQAAPVEIDTPGESQSTGSRFSILPLSAHTPAALVQVADQY
RSWLNAHPEATLADVCLTAGVARAHLEHRAALVVNSREAAVELLGAVADDRPAPGLGRGE
SYDAPKTAWLFTGQGSQYPGMARELFDTEPVFAETLKHCAAVVADVLEKPLLDVIFDVDG
PEAGEALRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAGVFSLEDG
ARLMAERGRLFGSLPAGGRMAAVFAAAERVESLTDEFPSLSVAAYNGANTVLSGPAQDLE
KAVAGLVAEGVRCDFLETSHAFHSALLDPILDEFESYAGQFNYKTPQRILIDNRTGAALG
RSTKLDGAYWRRHARQPVEFAKSVRTLADLNCKVLLEIGPQPVLTAAALRAWPDPATAPR
AIASLRRNTADHRQITEAAADAYVLGHVPNFGAFRHGHARKLDLPTYPFEHRQYWFSDRR
DADGRDATNQQQRAGGPRTEAVRLLEDGKIEELANLLGGAGGDQQTLAVLTKLAAQHNQQ
RTTQTIADDRYQFRWDKSPTPLSGTESGAGISWILVGEVSGAAAPLVDALTARGHQHRIL
GLPASDADEQQLADALRAEAADASAQGQTLRIVHVAALDAGSPSARSLLRIQHQVLAGTR
RLFRAAAAAQLRSPIWLLTRGAQRIIDADTVAPEQSALWGFGRAAALELPQVWGGLADLA
DASADEWSQFIARASASTDAAVREDQIALRDHAVYVPRLVRREELPSGKPLEVRDSATYL
VTGGLGSIGLEIAGYLAAHGAKNLVLTSRREPSESARQRIDALGAQHGCEIRVVTADVAD
AHDVARLLAGVQAELPPLAGIVHAAGEIGTTPLSDLDDAEVDRVFAGKVWGAWHLSEAAA
DLKLDFFISTSSIASIWGGFGQTAYSAANAFLDGLAWRLREQGIAGTSVNFGPWSAGMAD
AESRARLEQRGIKTLSPADALAGLADVASASSPQGVIARIDWARFLPLYQQAGRRAFLAE
LEREVPSHLAASPLVTPSGKTQLVERLASAPVQQRKKLLTDYLRDAVAEVTRVDVSEIRE
DAGFFDLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLGEVLGLNEQVKS
APRQAATTRTDEPIAIVAVSCRFPGAPDPEAFWDLLSGGVDAIREVPEDRYDIDEFYDPD
PEVAGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYSPAA
LRGSRTGVFAGVGANEYAHLLSSESLDKIEPYFITGNALNAISGRVAFALGFEGPAVAVD
TACSSALVAVHQAVQALHSGDCDLAVAGGVNVLLSPVTVIAASRARMLSPVGRCKTFDAS
ADGYVRSEGCGILVLKRLSDAQRDEDRILAVIPGSAVNQDGASSGLTVPNGGAQQRLIGT
VLDRAGLAGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGGSRDADRPLLMGSVKSNIGHTE
SASGAAGLIKVVLSLQNGVLPQSLHFEKPSPHIPWDSLSVRVVDKAIPWEANGRPRRAGV
SSFGFTGTNAHVLIEEAPQRPTDVDEGATDVPDVAPEPQGDQVSVLPLSARSPEALAAVA
QRYESWLSAHPDVDIEDVCVTAGRGRSHFEHRAALVVDSVESAREGLAELVQNRLRPGVV
RGEHTNHPTTAWLFTGQGSQYPGMARELFEAEPVFAETVTRCAEAVKDIVTSPLLEVMFA
TDRETGGEAGKVLRHTSFAQPAIFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGV
FSLEDGVRLIAERGRLFGSLPAGGRMVAVFSDAKHVEQIAGEFPHVSIGAYNGPNTVLSG
PGEDVEQAVARFEAEGIRCTWLETSHAFHSELLDPVLDEFESYAAQVQFAIPTLPLVCNR
TGAVLTAQTPIDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPE
HLAAPRAIVSLRKGVGDRRQIAEALAAAYVGGHRPNFAALQRHPRNTLELPTYPFQRRRF
WPKSSGAAIEGGGGLTAGILGRGEDLASGDSVYISRLSVRSQPWLSDHVIYGTVVVPGAT
YAAMALAAVGTPARAKDVFFYEPIILPEKSSREVQLTLHPLEDGSGSKFQVHSRPYGERD
VDWSLNAEGTVVTGIGDDAAEPTSEASEPVDAAIERMERMRPMELFEIFADLELSWGPTW
SGSLKSLWLGQGEAIGDVLVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGIN
DLFLPLRYGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYLDRDGRHLGGIREFTVK
RAPREALLRGLGGDATRLLYTLGWHEVPVPPSEDAAVEASGTWLIAGFDELAAKVPGCIP
FDRTTNPELLGQVLEQAKERGVPFSGVVWRAAGPGAQEGAGFSDTEIARLETEIANLLSA
VHTVQNGSQNGVKLPDGLWIVTERAVATESGEPVDPVQASLWGFGRTTINEEPALHARLV
DCDGSPEAVQALANLLGTPGHEPAEPEIAVRQGKLLASRLLPWSRTGHLTVPRGSDYVLA
PTERGAIDNLRITEKEVPAPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGI
VTQLGEGATGVEVGQRVYGSMQGAFGSRFNVPAQFLAPIPDGISGVEAATIPAAALTVRL
SFDWAQLKPGDKVLIHAASGGVGLAAIQMAQQFGAEVFATASTFKRATLRKLGVKYVYDS
RTTDFADQILADTEGAGVDVVLNSLTSEGFIEATLRATATNGRFAEIAKRDIWTTEQMAQ
ARPDIAYEIVALDTVMFQEPDRIRTLLTEVSEGLAKGEWTPLPAEIYPLTEARTAFRRMQ
QARHIGKIVCQMPNPLAPRPDRTYLITGGLGAIGLHTAGYLAQLGAGDIVLTSRRAPDTD
AQLLIEEITERSKTRIHVFTADVGEESEVVKLLERIRAELPPLAGVAHLAGVLDDALLGQ
QSVERFRTTLAPKAFGAEYLDRLTKEDDLDFFIVSSSVSSLFGSPGQSNYATANALLDGL
IAQRRAQGLPATGINFGPWGQGGMASSEAATANISAQGLIPLDPSAALAALAEVIANGTG
QATVIKANWQRAAKVLGSSRPPILDLVLPSAVGEVTGDSELLKQLMEIPVPQRAGFVTEF
LQREVQNFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPSIG
GLAEYLVAQLPDAESESEEAQPAVESAEADSDAAPTPSDAVSEPKE
>Q3M9Y1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Trichormus variabilis (strain ATCC 29413 / PCC 7937)|TrEMBL
MSANPIDTALAELEAQINNCEKALLRCIEEKKMKSEKPMSINKINRQLQHNPIAIIGMAS
LLPEARNLREYWQNIVNKIDCITDVPSTHWSVEDYYDPNPRTTEDKTYCKRGGFIPEVDF
NPMEFGIPPSILEVTDVSQLLSLVVAKEAMEDAGYGESREFNRDLVGVILGVAMAKQLGM
PLSARLEYPIWEKVLKNSGLSDEDTKKIVDKIKSAYVKWDENAFPGMLANVVAGRIANRL
NFGGMNCVVDAACASSFGALKMAISELVEHRADMMLTGGVDTDNTIMAYISFSKTPAVSP
GDNVKPFDAKSDGMMLGEGICMLVLKRLEDAERDGDRIYAVIKGIGTSSDGRYKSIYAPR
KEGQVNALRRAYEDAGFSPATVGLMEAHGTGTMAGDPTEFGSLRDFFGEHDKKKQHIALG
SVKSQIGHTKAAAGAASLVKTALALHHKVLPATINITEPNPKLNITESAFYLNTETRPWI
RPEGEPPRRAGVSSFGFGGTNYHVVLEEHEAEQNRPYRLHNSASEILLFAANPAELLKQC
EEVLGKLQSEGGDKHYSQLVRDCQALQIPQNAARVGFVAENLQEACKFMQTSIDWLKHKA
GVANWEHPQGIYYRASGMELNGKVVSLFSGQGSQYLEMGRELVMNFPTLRRLFGYMDGLL
LKDNLRPLSEIVFPHPVFSEAEKNAQVAALQRTEYAQPAIGAFSAGLYAILKQAGFKSDF
VAGHSFGEITALWAAGVLSDADYMYLVKARGQAMAAPEDPDHDAGTMLAVKEDLSKIEPI
LKQFPQVSIANYNSPTQIVLAGPTAEIAKVRQALQAQGYAAVPLPVSAAFHTSLIAFAQK
SFAIATKSVQFNEPKIPVFTNVTGKPYPKEPQAIQKILETHLANSVLFKQEIENIYAAGG
HCFVEFGPKRILTNLVKDILGDRPHITVSLNPSTQKNSDRSLREAAVQMRVIGMQLQNLD
PYQAPPALPPTETKKGLSVTLRGINYRSEKTKKAWEDAMNDGFKVSLPPAPTVTVPPVKE
TNGNGHSKISELPKIINNSTSVTPVKPEMNSAIVSPQLVEEKKMQTPEKLDNYKRVLESL
EYLTTQFQQNQTENLQVHGTYLNHQMEYTKAFFQLMQQQNTLFANAKSSQEAAQLKLVVM
ESLERSMMQFHSQQGETLRIHEKYLQEQVAYAREFFELIQQQYSMVLSGQVNPPATPTPV
KEVPAFTIEAPVTPTPKIVEPQPESVVKNGFSIVDAPIPPAPTTWEIQSELVVTAPASVV
STIEPEPVIAAPVVNQVAEFTPAPAPVVAPVITPAIDVADLDKNLLAIISDKTGYPVEML
ELEMDMEADLGIDSIKRVEILGGLQEVYPDLPKPNLEELAEKRTIGQIVDYLKANTAISQ
SVGIAIQQAQQAAEMPTLVVTASIPTPAPVVVPEPVAIPATPAPAAPTDTSDYADLGQTL
LNITSDKTGYPVEMLELDMDMEADLGIDSIKRVEILGAMQEAYPNLPKPNIEELGDLRTI
RQIVDYLQKLAGGEKKKSQSERDWQPVSIIGNVPRCPAKLKYLPTPDSLDFSLPEGHICL
ITDDGSLTTSQVAQSLTERGWKVVVLSFPQSLVPHQSTLPASVHRVTLADMSEELLQHKL
SAIATNYGKIGAFIHIHPVFQNLGIYIPQEKSIVKHVFFLAKHLKKSLTEAGRYERSCFV
TVTRLDGAFGLEHNTNFGAIAGGLFGLVKTLRWEWPNVFTRGIDLSPALNPQQSAQFILD
ELHDSNLYIPEVAYGSQGRVTLIS
>Q3M3U5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Trichormus variabilis (strain ATCC 29413 / PCC 7937)|TrEMBL
MKSQSCHQINVAQTPLWGMGQVIALEYPHLWGGLIDFGKQDVFATAMIAEMTAKTGEDRV
AFRDGKRYVARLMPISAPLPTPQPLISDGSYLITGGLGALGLTLAEWLVQQGARHLVLTS
RQGLLNQSEEKQQKIRALENQGATVKVVAADVSDYQQMSQLFAEIQLNSPKLRGIIHAAG
VLNDCSISQMDWETFAKVFQPKVTGAWNLHQLTQDLSLDFFVCFSSMSALLGSRGQLHYA
AANSFLDGLIYHRQTLGLPGLSINWGPWAEGGMATQGYEVGLKRMGIEPLEPTAALQVLG
GLLGSASVQTMVAAINWSAFGKIVAAKGRVAFLAALLTQESQDGSNGESFCQKLAAAPLH
RRAALLTTQVQQEVAQVLGHSGSYVPEIEQGFFDMGMDSLMSVQLRHRLEALLAVSLPST
LVFECPSIGDVVSYLMREVFAWQLDGSDGSAMESPASLVIENTIAQLEGLSTAETEALME
QEIAELQALLS
>Q3MCQ1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Trichormus variabilis (strain ATCC 29413 / PCC 7937)|TrEMBL
MTIDSGYDNHEFNNSEIAIIAVAGRFPGAKDIASFWQNLRDGVESISRFTDEELLNSGVS
SDLLNSPNYVKAGSVLSDIELFDANFFAYSAKEAELIDPQQRLFLELAWEAVETAGYDPQ
TYHGLIGVYGGVGMNRYFLNNLYPHHQLLATIDPIQLGFSNDKDFLPTRAAYKLNLTGPA
VNIQTACSTSLVAIHIACQSLLNGECDMALAGGVTLSIPQKIGYLHQEGMILSPDGHCRA
FDAQAQGTIAGSGAGIVVLKRLKDAISDRDHICAIIRGSAINNDGAVKVGYTAPSVSGQA
AVIAEAQAIAGVDAETISYIEAHGTATPLGDPIEIAALTQAFHQTTDKKGFCAIGSLKTN
LGHLDTAAGVAGLIKTVLALQHKMLPPSLHFETPNPKIDFANSPFYVNTTLKEWETNNSP
RRAGVSSFGMGGTNAHVILEEAPIQGKSQNTLRECQGRTKFKNKYLLLCLSAKTGSALEK
ATGNLVAYLKEHPEVNLGDVAYTLNSGRRGFNYRRMLICQDLEDAVKGLESKQVATNYTE
ITERPVVFMFPGQGSQYVNMGREIYETEAVFKEQVDYCSEFLKPLLGLDLRDIIYPSDDK
IDAASKQLEQTGIAQPAIFVIEYALAQLWQSWGVKPQAAIAHSIGEYVAATLAEVFSLED
ALSLVTARGQMMQQLPTGAMLSIPLPVDQVQSLLGTELAIAAINVRSQCVVSGSIAAINT
LQNQLAAQGIECRRLHTSHAFHSHMMEPILEAFAERVQQVTLNPPKLPYISNLTGTWITV
TQATNPEYYAQHLRSPVLFAQGVEKLLATPEQVLLEVGPGHTLSTLVKRNPGKVATQTVL
TSIRHPQEKQSDIRVLFNTFGQLWLAGVKVDWLGFYSQDEYYRLPLPTYPFERQRYWIDP
PEKTAWGQLPTLPPTSQLWNLLTQAGQKQASVINAELNESTYQENKQWLDSLCTAYINTA
LRQLGAFNHSQEKYALENFWEQYHISPRYQQLFSRWLQILIEQGQLQQQEGLFTGLVPCS
QNYIDEHLAEVRARFAASSLVDLDLVQRCGENLAAIVTGEQEPLEIFNELVYQKENKASY
SESPLINYYNSILRSSLEQIVKSLPSSVHLRVLEIGAGTGVSTQALLPLLPPQQTNYTFT
DIGSGFLTQAQQKFQEYPFVEYRLLDIDKPPTEQGFEQYSFDVIIATNVLHATQNIDQTL
HHVRSLLAPGGFLLVWEITQPKIDFDISWGLLLKPLDDQRRDPGQPFIIKDQWFAALQAQ
DFVQVAAFPENEAFEHQIIMAQAAVSTAFSSKSGQQETKTKSNISLPIKPDSLQPEKLST
LHSRPNLANSYIAHRDEIEQKIADIWQESLGINQVGIHDDFFELGGDSLIAVQILSRLRN
TFAIGLNVASLFASPTIAEIALKIGKSLEPDTNSSAFDREEIAI
>A0A378SE01|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium gilvum|TrEMBL
MGSAAHQGESAHRFAIVGYAGRFPGARDAESFWELLADGRDAISEVPEDRWDVEAFFDPD
PSTPGKVVTRRAGFVDDVSGFDAPFFGMSTREVRLMDPQHRLLLETAWRAIEHSGTAPSE
LANTNTGVFVGLATHDYLGMASDELSYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV
DTACSSSLVAIHQACQALRLGECDLALAGGANVILTPATMITFSNAHMLAPDGRCKTFDA
AADGYVRGEGCGVIVIKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIG
DALSRAGLAPGDVDYLEAHGTGTSLGDPIEAQAAGAALGPGREPQRPLLIGSAKTNIGHL
EAAAGIAGVIKVVLSLEHETLPKHLNFENPSPHIPWDRLPVEVVKESIPWRRGQRGGRPR
IAGVSSFGFAGTNAHVILEEAPLAAEPAQESVDDGRFTLLPLSARTPAALMAVADRYRDW
LVANPDATLADLCFTAGTARSHLEHRAALVVNTREAALDLLGALADDRPAPGLVRGESHD
TPKTAWLFTGQGSQYPGMSRELFDTEPLFAETLRECAAAVDGMLEKPLLDVIFDTDGVLD
TDSNETLRHTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACVAGVLSLRDG
ARLMAERGRLFGSLPSGGRMAAVFAAAERVEALTDEYPALSVAAYNGANTVLSGPATDLE
RAVAGLVADGVRCDWLETSHAFHSALLDPILDDFESYARGITFTAPQRILIDNRTGAALG
RSVTLDAAYWRRHARQPVEFAKSVHTLADMNCKLLVEIGPRPVLTAAALSAWPDPATSPR
VIASLRRTTADQRQITEAVADAYVLGHLPRFAAFRRDGARVLDLPTYPFEHRQYWFSDSR
EPVAAAPQRGARTETVRLLEDGRIEELAALLGGTVDDPFTFDVLNRLAAQHNQQRSTESI
ADDRYQIRWETAAEPPVGADAADGITWLLVGDDTDATRPLVDVLAARGHRYRILGLPKSG
AEEHELADTLRDAAADATDLRIVHVAALDAAESDTSMKSLLRMQHRVLGGTRRLFGAAVA
AQLRSPMWLVTRGAQHVTDTDVVAPDQTCLWGFGRAASLEHPQIWGGLADLGGGTSDEWS
RLLNRIAATHDPAVMEDQVAVRGSTSYVPRLVHRDTLPSGKPLHLRADATYLVTGGLGSL
GLEIAGYLAANGAGHLVLTSRRTPDEAAASRIEALRERHGCEVRVVTADVADAHAVARLL
ATVQAEMPPLAGIVHAAGEIGTTPLADLDDAEVDRVFAGKVWGAWHLSEATSDLQLDFFI
STSSIASVWGGFGQAAYGAANAFLDGLAWRLREQGVAGVSVNFGPWSAGMADAQSRARLE
QRGIKTLSPADALAGLSDAVISAAPHPVVARVDWSRFLPLYQQAGRRGFLAELERELPAA
PAQQGPAVTASGRTPLVERLTTAPLQQRKRLLTDYLRDAVAEVTRVDAAEIREDAGFFDL
GMDSLMAVELRRRIETGVGKEIPVTLVMDHPRLSDAADYLLGDVLGLTEAATAPKAATVV
STAADEPIAIVAVSCRFPGAPNPEAFWDLLSGGVDAIREVPEDRFDIDEFYDPDPDAAGK
TYTRYGGFLDHIDEFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSALRGSRT
GVFVGVAANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTACSSS
LVAVHQATQALRSGDCDMALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVR
SEGCGILVLKRLSDAVRDGDRVCAVIAGSAVNQDGASSGLTVPNGGAQQRLIGTVLARAG
ITGGEVDYLEAHGTGTPLGDPIEVQAAAAAYAGARDADRPLLMGSVKTNIGHTESASGAA
GLIKVVLSLQHETLPQSLHFDTPSPHIPWDSLPVRVVDTAMPWQPNGRPRRAGVSSFGFT
GTNAHVLIEEAPTDLAGPTEPTAPAEPVDEDAAADPAPAPVEVLPLSARSPEALVALAQR
YETWLTAHPEADLADVCRTAGTGRSHFEHRAALVVDSVESARIALTDLAQNRLRPGVVRG
EHLNHPTTAWMFTGQGSQYPGMARELFDTEPVFADTVTRCADAVADLLPRPLLDVMFAGG
REAGVPPTETLRHTSFAQPALFAVEMGLARLWQSWGIVPDVVLGHSVGQYAAACVAGVFS
LEDGARLMAERGRLFGSLPEGGRMVAVFADAKRVEQVAAEFPRVSVGAYNGPNTVLSGPG
EDLEQIVGTFGEDGIRCTWLETSHAFHSELLDPVLDEFESYAAQLQFAAPTLPLVCNRTG
AVLTGQTSLDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHM
AAPRAIASLRKGVADRRQIADALAAAYIGGHKPDFAALHEQRGVRLELPTYPFQRRRFWP
KSAGMAIDGGVGASAGSGILGSGKDLASGDSVYTSRLSVKTQPWLSDHVIYGTVVVPGAT
YAAMALAAVGTPAHAKDVFFYEPIILPEKSSREVQLTVHPSVDGESKFQVHSRPYGERGA
EWALNAEGVVASGVGDSPAAAGDLEDPVDEAIERLNRMRPQELFETFADLELAWGPTWSG
SLKSLWLGEGEAIGDILVGAELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDL
YLPLRYGQVSLQEKMPRRFYCRATWHEAPLDSETQVFDLEYLDRDGRHLGGIREFTVKRA
PREALLRGLGGDATRLLYTLGWHEVPVPESGDGAAPQGTWLIGGFDELAASVPGCIPADR
TNPESLRQLLTDAHGRGLPFSGVVWRAARSDGDESDAEVAARLEAEIAELLGAVHTVQGG
EVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTAINEEPALRCRLVDCDGSPQAVQ
ALAALLSTPVDEPELAVRQGKLLASRLLPWSRSGHLTVPRGGDYVLAPTERGAIDNLRLT
DSEVPPPAEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGEGVTGLDV
GQRVYGSMQGAFASRFNVPGQFLAPIPDGVSAVEAATIPAAALTVRLSFDWAQVKSGDKV
LIHAASGGVGLAAVQMAQQCGAEVYATASTFKRATLRKLGVKHVYDSRTTDFAEQILADT
DGAGVDVVLNSLTSEGFIEATLRATAQGGRFAEIAKRDIWTVEQMAAARPDLAYEIVALD
TVMFTEPDRIRDLLTEVSTGLRDGVWTPLPAEVYPLTEARAAFRRMQQARHIGKIVVQIP
NPLQPQPDRSYLITGGLGAIGLHTAGYLAQLGAGDIVLTSRRAPDAAAQQAIADIADRTK
ARLHVFTADVGVEADVAALLERIRAELPPLAGVAHLAGVLDDALLSQQSVERFRTALAPK
AFGAVHLDRLTRADDLDFFLVSSSVSSLFGSPGQSNYATANAFLDGLVAQRRAQGLPATG
VNFGPWARGGMASSEAAAANISAQGLIPLEPSAALTAMAEVVANGTAQATVLKANWQRAA
KVLGSSRPPILDLVLPSAVGEITGDSELLKQLQEIPVPQRAGFVTEFLQKEVQNFLRLAQ
PPAATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYPTIGGLAEYLVAQLPDA
ETPQSAPQSESEPGPDVTE
>A0A100JB32|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MTQSAELGVAVVSDRMVVHAFAGQGDFTLAPLLRALDAQDVVEEALEEVAAEGDPVAGEF
GVAPVVSRLLSGELRSSRELADGPVGTPQYALFACSVAVHRALCRSGLAPDRVVGMSFGD
IAACVAAGILDIADGTRVACLVARALTGHPGGMLLVEPPVTDGDLEAEAHRLLAALDLPG
LTLACVNDDRRVILTGPSDAVGLAEQLLLGLALPAVRLRLPFLCHHPELEDDARQFVDAI
RDVRVEMAQLPVYSSLLGRAYRPDDDVREVLSYGLTRPARLPGVLRQSVDGGPAMLLEAG
TGSALTRSARELFAEEDVATVDGFAWVTGVPHGR
>A0A1B9ESC0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. PTY087I2|TrEMBL
MSRELDMTVALFPGQGAYRPGALKEFWESGDRTVRSTFEEVDAAAKELVGRAVSPTVFQP
SPPSPAALLESAPDVLQLAVFTTAVATHRLLAERGAAPSVHLGHSLGELAALTCAGAWDL
ADAAKILCERISVLREHDHSGGVMLALGCDRERAERIVGLIGDPGLVLAVDNGPQSVLSG
RAEPIATAEAVAAQLGIARTRLRSPHPFHHPLLENARGVLAERLASFPSRPLDVPVYSPI
LGRFYRDGDDLARLLALHLVTPVEFGPAVSALHAAGARVFVEAGAGRVLSALVEEARPGV
HVVAPLAGRDEEAGLAAAADALRSPLTRGSVPVSTGPESAALTSPVTPPAPVVPEAVPET
AAVATPPVPDRDELVGRVRALYAEAMEYPEEVFTDDVQLEADLGVDSVKQTELLSRLGDR
FGLGLPPTGLRVADYDTFGKVVDFVAAGVTDGADTGSAAGR
>A0A378AQY2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Klebsiella pneumoniae|TrEMBL
MAIPPRLRFFATLALPTVAANDTIALHPALLDIASSVVEQLPGFHTDSVPFLYQDLRLYR
PLPNTLHVALTVNRHDEEGDSYAFTLYDMAGEMVARCAAMVKHKVQLHIQDVDDDTRLRV
PSADNYQLRLAAEGEGAGKLALCPTPRLALGDSQVEIEVLATGLNFKDVLFTTGLLRQQP
GEAPLQLGLECAGRITRVGKNVTEFAPGEDVMAVLNGGFVQYARVESDCVVRKPAHCRIE
QAAALPIAYLTAYYALVVRANLQPGERVLIHSAAGALAWLRYILPNAAEHRSSPQQVASR
NAITCFR
>G8NU15|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8)|TrEMBL
MNPQGTASLKAALEELRLRRREIETLRAERNQPIAIIGAACRFPGGSITPERFWDLLDGE
RNAVSEIPRDRWNIDEYYDADPATPGKMATRYGAFLEQIDRFDAAFFNIAPREALFLDPQ
QKLLLEVAWEALENSNISPKSIEGSRTGVYVGITTFDHAIRLGSLPTQSSSYVGTGTALN
MAAGRLSYVLGLTGPSMAIDTACSSSLVSLHLACESLRSGDTKMALAGGVHLILSPEVMV
SFSQARMLSPDGRSKAFDAAADGYVRGEGCGIVVLKRLDDAVADGDRILGVVRGTAVDQD
GASGGLTVPSRASQERVMRRALEQAGLAPEEIGYIEAHGTGTSLGDPIEVEAQTHVYGAN
RPAASPLPIGSVKTNIGHLESAAGIAGLIKILLSFKNGRIPAQLHLERLNPLTPWASIPI
TVAQEPISWPTGKAKRIAGLSSFGFSGTTAHALIEEPPAMAPRAIGRTTLLVSAKSATAL
ESLTKDYRQMLEGASAEEISAVCRSAAVGRSHFSFRAAHVFSSNSTFTGQIKRGKAFRLA
FCLDLQDERAVRSAAELYQTEAAFRRAFDSCGVPLDALYSRLGRFAAGYAWAQLWRSWSV
EPYVVLGIGAGQLVAACLAGVMKREDAQRLLAAWDSEQEWGQILREIRLAQPSVKLISSD
SGEQISSSQASDPSYWTKQRNISLSRGKVRQELGLLAIDATLGSLRAGASLERAVAALYI
RGLSADWDRIFVESGQPEGMLPNYPFERQRFWLEKPEVAAVVNSSVHSQVLPTTPVGDPA
IQRWFSHISWEEMPAKSMALTEPRGSSWLIFADQDGLGRRLARLLAARGVVCTLVNAGAA
EIRASGMEALKEVSIDPRNGEQFQELISHFGGDNRRIVFLWGLDKGEPFSHAAALLLLVQ
KVSTIRPKNSVKLWVVTRDVVGAGSSPQISGLTHASMRGLAKGALAEHSDLFGSLIDLAQ
TASDDEPEVLLAEILNGGREDQVALRSGMRYAARLTRPIQAPVYSPLRVDPDASYLITGG
FGALGMRTAEWLIARGARSLILTGRQGPATRNAHEAITVLRSRGVTVQAEACDIGDAGQV
RKLFERLAGGVAPLRGIIHAAGVAGYKAFLEVDFADLEAVLRPKTVGAWLLHDHSRHLPL
DFFILYSSIASVWGSPKQAHYMAANSYLDSLAHYRQMLGLPATSINWGPWAQGGMTSQVT
ETLLRGIGINTFDPATALDALDYLSGTTQVTIADVDWNVFQQSYEARGQRSFLDSIRGLI
DNVTHVDTTPHIAAPPAYMRLSSGERRRFFAELIEQKTADVLGFGTGYQQGTLDRDQGFF
DMGMDSLMAVELRSQLQKATGVSLPATVLFDQPSIHALADALLEHSGTFAETSSATVSSL
RETRSISPHQERSRAVGTPGPVASFASSTPTQSFSLKEDADEGVAIIGMSCRFPGDADSL
DAYWRLLRDGVDAITEIPGERWDVEAYYDPDTEAKGRTYNRHGGFLRNVDQFDPAFFKLT
PREAASMDPQHRLLLEVSHEALEHAGLPAESLKGSQTGVYVGITTNDYANLQLKNASTSP
IDSYFLSGNPLNAAAGRLSYFFGFHGPSLVLDTACSSSLAAIHTACQNLRHGECDLALAG
GVNLILSPDNTVALSRARALSRKGRCSTFSAGADGFVRSEGCGVLVLKRLVDAKAAGDRI
LGIVRGSAVNHDGASTGFTAPNGRAQEAVMRSALGKIPAASVDYVEAHGTGTPLGDPIEV
QALAAVYGKDRIGHNKLLIGSAKTNIGHTESAAGMAGVIKMLLAFEHEQIPAHLHCEQPS
EIIPWHAIAIEVCSYRLSWPRTERPRRAGVSSFGASGTNAHLILEEAPLAASAALESKRE
VYPLVLSAKTDMALLELAARYERWLGANPELDIAAVSASASVGRSHWSHRLAMAVSSRED
AVAMLKQFQQGDKKEVRRQVAARIAFLFTGQGSQYAGMGQYLYKTYPVFREVLDRCCAIA
DPLLPGSLLDAMFFRKEVLDQTAFCQPALFSFQVALVALLKQFGVSPDAVIGHSVGEFAA
AVAADVFSLEDGLRIILERGRLMQELPATGKMVAVLADISIVQEVIAPYSSTISIAAVNG
SLNTVISGEVSSIAAVLDVLSARQVRFIPLNTSHAFHSSLIEPMLDRFEASARAVHVAPP
AIPLYSNLTGTLHREALDGNYWRRHARQAVQFSAGIQSLVGDGLDVLIEIGPNAVLLGMA
RASLPAGWQGESVGVQGPQREEEAFIGALLKLYRRGMDIRWAAFQPQPAHRIDLPQYAFQ
RERVWFEAKGSPAVQPLANPLLSSDQPIPSGGTTEDWLRTKMSELIHVASETLDIDQSFL
DMGTDSIVLIEATLLIEKQYGTKLSMGRFFNDLHTVRLLAAYLDKNYPRKNYPPQVPKAV
ELITPAVSSPENSAAPSEQSVERMLLEQNQMLIRLLADQADLVRSILGKSAPESGMNRPI
ATTWETADSQDGSSVVTRPGSSPSRTAVDEPSDRPPLLRQERPEQVPLSYAQERLWMLEQ
LGVPGGAYTISAGMRLPGDLDVSAFESAMAALTERHESLRTRFRSRDGVAYQVIDPAGRV
SIPVEDLSHLSREDRKRELQRIGAEEVSKSFDLETGPLLRVRLLRLEATEHVILLAMHHI
ISDGWSMGVLIREIGMLYSGFTRGLSAKLAPLPVQYVDYALWQRGWLQGEALERQRRYWQ
EQLAGAPTALELPLDYVRPKQQSFRGATLPVELGATLTSALERLARKEGATLFMVLLSAF
QLVLSRWSGQDDVVVGTPIANRTEPAAEGLIGFFVNTLALRAELKNSGSFRELLVQVRER
TLGAYAHQDLPFEQVVELLRPERDMGRQPVFQAMLALNLVPEELTLPGLAAERIEFEALT
TNFDLTLNLTASPEGLSGRLEYATDLFAPATMERLYGSFRRVLEAVVTDPEQPIGKIALL
SVEERDQLLVGWNATEIPYPSEATIHSLFEGHVEQSPEATAVVFEEESLSYGELNRRANR
LAHELVDLGVRPDDRVAICVARSLEMVVAQLAVLKAGGAYVPLDPAYPVDRLSYMLADSG
PVAVLTHGVARGTLKQALGGLEVPVLDLDLEASWHNRPETNPDAKALGLRSTHLAYVIYT
SGSTGQPKGVLIEHRGVVNMIEALKSHYRIVQSDRMLQFASSAFDMSIEEIFGALLSGAT
LVLRSDRWLKSNEGFIACCKCFKITIANLPSAFWEQLIKEEALAIPQCLRQIMIGGQAVS
QSALVRWFKRDGHRPRLINAYGPTEASVNSTLLDVRPEDVIHSSIGRPISNTRIYLLDEY
GEPVPVGVAGELYVGGAGVGRGYLNRAELTAERFIASPFVAGDRLYKTGDLARYLSDGNI
EYLGRNDFQVKIRGFRIELGEIESLLCQHAGVGEAVVVARGAAEDKRLVAYYTAAVGASV
EVELLRGHLSATLPGYMVPSAYVRMESFPLSPNGKLDRKALPAPDDEAYVRRGYEAPVGE
MEETVARVFAEVLGVERVGRNDSFFELGGHSLMAMRVLSRLHSAKLRIDVRDLFSYPVVQ
DLAARIPFLELALLPAIERVQEHQDLPLSFAQQRLWFLSQMEGVSEAYHMPAALRLSGTL
NQAALQFALDRIVARHEVLRTRFVVVEGEPVQRIDGAEAGFTLERRDLSGVPDQEERLSI
LVVEEARAGFDLERGPLVRGCLVRLGEQEHALLVTMHHIVSDGWSIGILVKEFGALYAAS
CAQEVDPLPELSIQYGDYAHWQRQWLGGEALEPQAEYWGRTLSGSPTLLSLPSDYRRPAQ
QSYAGGRVSLELDRDLTERLKALSQRHGTTLFMTVLSGFAVLLSRLSGEQDVVIGTPVAN
RTQRETEELIGFFVNMLALRVDFTGQPTVSELLKRVRQTSIGAQAHQELPFEQVVERLKP
SRSLAHSPIFQVMFAWQNNEVSDLDLPGLRLSGLESESSVAKFDLTLDLSETDAGIVGSL
EYATSLFRSETVERYGQYLVRLLEAMTRGEDERVSQLSMLPAEEREQLLVEWNATEVAYP
SESTVHGLFEAQVEGSPESTALVFEEERVSYGELNCRANRLAHELLELGVRPDDRVAICV
ERSVAMVVALLGVLKAGGAYVPLDPAYPVDRLSYMLADSGPVAVLTHGAARETLEQALGE
LEIPVLDLDLEASWHNRPETNPDAQALGLRSSHLAYVIYTSGSTGTPKGVMVEHRNTVNL
LCSFAQMLVIETSDVLAAVTPISFDISGLELWLPLLHGAKIVLVPRKISAAGEALAELVI
DNKVSILQATPATWRLLANADPTKRYELKVLCGGEAMPHDLLPILPNFGADVFNVYGPTE
TTIWSTAYLCNINENSVPSIGRPISNTRIYILDEHGEPVPVGVAGELYIGGAGVGRGYLN
RAELTAERFIASPFVAGDRLYKTGDLARYLSDGNIEYLGRNDFQVKIRGFRIELGEIESL
LCQHAGVGEAVVVARGEAEEKRLVAYYTAAVGASVEVELLRGHLSATLPGYMVPSAYVRM
ESFPLSPNGKLDRKALPAPDDEAYVRRGYEAPVGEMEETVARVFAEVLGVERVGRNDSFF
ELGGHSLMAVRVIARLEEQLGIKMSVREIFNKPTIASLGLWIDLTSERLTSDAELQTLVE
NLSAEEVSQLLLGEK
>C7QKD1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)|TrEMBL
MSNTRSGIGDTKIAVVGIALRYPDAESPDELWRNVLAGRRAFRKLPDERMRAEDYYSPDP
TAPDRHYSKMAAVLEGFEFDRVGYRIGGSTFRSTDMTHWLALDTVSRALEDAGFAGGEGL
PRANTGVVIGNTLTGEFSRANLMRLRWPYVERTVGAALREAGWDDVALGEFLTSLEARYK
APFPPIDEDSLAGGLANTISGRICNYFDFGGGGYTVDGACSSSLLSVATVCNALASGQID
AAVAGGVDLSIDPFEVIGFAKTGALAKSEMKVYDKGSNGFWPGEGCGMLVLMRDEDAVAQ
GKFRYATINGWGQSSDGKGGITRPEASGHRRAISRAYAQAGFGVETVRYFEGHGTGTAVG
DATELDAISGARRDAAGLEAGTAAISTVKGNFGHTKGAAGVAGLIKAILAVRHQVIPPAT
GHYDPHPVLLAEDATLHVPDTAELWPDGAPIRAGVSSMGFGGINAHLIVEHADGVRRRGI
SKSTTQLVRSRQDCEILLLDAVGIAELRGRVAQLAGFVTKLSFAELGDLAATLSGELSGQ
PLRAAIVASSPEQAEDRLGRLLSLLDSGARQVLDAKGGVFLGSAGRMPRLAFLFPGQGAG
RRADGGALRRRFPAVDELYQDLALPTDGDQVATSVAQPRIVAGSVAAMRVLSALGISATG
AAGHSLGELTALHWAGVMSEEAVLALAAERGRVMDEASSGGGAMASITASAADVNALLYS
EPVVIAGYNSPTQTVVSGPVEAVESVMARAQARGLSATRISVSHAFHSSAVAPAAEMFGR
HLAAQDFSPVDRTVVSTVTGAALPADTDVTTLLTTQMLDPVRFHDAVSALARDCDAFIEV
GPGRILRNLATEIAPATPAVSIESDSMSLTGLFHAVAMAYVLGSPVEHAELFRDRYVKPL
PLDKEFVFLASPAEAAPEGDFAVVKAAMAAAPASQGAAQPAQTGAAAAEGGSGTTAADAL
SVLVRLAAERAELPPEAVSPDSNPIDELHLSSITVGQIVTQAAKELGVTAVLATSAYATS
TLTELAVMLEGLASTALADDGAAEQIAGVEPWVRAYAIDLVPTPPAPPAVVKHPVAQWEV
FASDGHRLAEPLGAALAVAGIGEGVLLCLPDEAHEDHTELMITAVRAALSRVRQEPVRFV
TVGGRRGAAGIAKTLHLEAPSVTTTVVAMANPDTVPEDGIAEVVTRITADAAMTAGFAEV
GYEADGTRTVPILRPLATTAASAPSTGLGDALGRDDVLLVTGGGKGITAEAAMGLAQDSG
ASLALMGRSEPAKDPELAMNLERMRAQGIPFLYVQADVTAADEVKDAVERVRRTLGPVTA
ILHGAGRNEPRSLVDLDESTFRRTLAPKLDGLRTVLTAVGSDPLKLLITFGSIIGRAGLR
GEGDYATANAWLTELTHQVAADRPEVRCLALEWSVWSGAGMGDKLGVLEALMRDGISPIP
VAEGVGILKALLADPSTPGTVVIAGRAEGLPTITMEQRELPLGRFLERPRVFYPGVELVV
DADLTPSADLYLGDHLLDGDLLFPAVLGMEAMSQAAGALTGHDGAPTLENVEFLRPIVVP
VDGRTTLRVALLADGPDVVRAALRSSETGFQADHFRATLRYDQPLPAGDARPVDRDTAPR
IPLDPAAELYGPVLFQGDRFQRLLGYHELEARGCVAAISNQARDDWFGSFHPADLILADP
GTRDALMHSIQCCVPDATLLPASVERLWLADPKRARPLPEVTLHAAERSRTGDTYIYDIE
VRDLDGVLVERWDGLTLQAVRKQDGTGPWLPALLTPYLERNVEPVFGRTGLRTGVIPDAA
APGASEAEDSVSALRRERTDRAMSWAVGRRVEVGHRSDGMPWVDGYQVSSSHGAGLTFST
ALAGDRPVECDVEVAMTRTEGEWTDLLGAEGAALARLISTERNEDYSVAATRVWGAIECL
SKSGQAVRNLTLDTVDGIPGSGPWAALRGGGRRIASFATTVRDTNEPLVFTVSAADAADE
GSDAR
>A0A386A1F4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces griseorubiginosus|TrEMBL
MPKAYVFTRYGGPETEAFVDVDRPSPGPGELLVAVRAAGVNPVDWKIRSGYVRPGDTGER
VFPAVFGSEVSGVVAETGADVEGFAVGDEVFGNTLTGGYAEYALIPVAIAAHKPAGLSHA
DAATLPVAAATAYDGVRQLGLPEGATLLVTGAGGGVGAAAVQIARALGLKAVGVAGEAKK
EFVESLGAVHVASGPGWAERARATAPDAVYDLVGGEVLVEAAELLADRTRLITAGAPEED
VRRLGGARVVRARDAAVLEEVARLVVAGDLDPHVTATFPLDRAADALRTVEEGHARGKTV
IEVAR
>G8SJL3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)|TrEMBL
MATDDKVLEYLKRVTADLHQTRRQLQEREEADAEPIAIIGMACRYPGGADTPEQLWGLVA
GGTDAIAAFPGDRGWDLGPDSAGFARVGGFLDGAGDFDPAFFGMSPREALVTDPQQRLVL
ETAWEAFERAGIAPATVRGQAVGVYIGSGMQDYGALLDLSPELTEAFLGTAATSAVISGR
LSFVLGLEGPSLTVDTACSSSLVALHLAGQALRAGECTLALAGGVMVMATPGPFQAMSRQ
GGLSSDGRCKSFAAGADGTAWGEGAGVLLVERLSDAQRLGHPILAVVRGSAVNSDGASNG
LTAPNGPSQRRVIRKALASARLSSADVDVVEAHGTGTVLGDPIEAQALLETYGQDRERPL
LLGSIKSNIGHTQAAAGVAGVIKMVMAMRHGVAPRSLHLDEPTPHVDWSTGNIRLLSEPQ
EWVADGRPRRAGVSSFGISGTNAHVIIEQAETVAPPGDDQGPVVLPLSARTPDALADLAE
RLRGVAGDLRPVDVGYSVATGRQVFEQRAAVVAGSRTELTDRLSTVTASTARAGDLGVVF
TGQGSQRLGMGRELHARFAVFAAAFDEVLAGFTADVRKVVWGDDAEALNRTGSAQPALFA
FEVALFRLFESWGIRPTVLGGHSIGELAAAYVAGVWSLEDACRLVEARGRLMQALPAGGA
MVALPVSADQLVLTPGVGIAALNGPTSTVISGVESEVLAIAEQFPNARRLKVSHAFHSPL
MEPMLAEFAEIAGGVTYHQSSLPILTSGDVTDPAFWVAHVRDAVRFTDTVTRMIDHGVGT
VLEIGPDSTLTTLIGYNTDELATIPAQQRDTGELLATATAAGRLFETGTAIDWTAFYAGR
DPRQVELPTYPFQRDRYWLDAEFRAADVASAGIDSTDHPLLGAVVTLADPDTVVLTGRLS
LPTHRWVADHVIAGAVLFPGTGFVELAVQAGDQVGHDVVQDLSLIAPLVLTETDRFQIRV
VVGAPEAGRRPLSIYSRPEGASTEPWLLHATGQLAAASATTSPGASLSGTWPPAGAEPIE
VGEVYRELAEGGYTYGPAFRNLRAAWTSGSDVYAEIAPENLGTDRFLLHPALLDAALHAV
SHTGVLGDSAVVPFSFTGVTLRASGAAALRVRLSHTGPRTLSITIADSAGSPVATVDSLV
MRPISEAVGSAAEPVHQLVWQPIDNAGAAAPTAGTGHAAGGAAQAISAAANVTGQALSAA
ATATGQALSAAVTATAQALSVAAQAISAAAHGTGRAAGPAAPAATASAHATSGAVYATGP
DGAQVEVVEAGAFDPGPGAAVPLRVRAVLAGVLRKLQEGTAVVVVTRYAVAVADGDVVDV
VQAPVWGLVRSAQAENLGRIVLVDTDGGDIAGALASGEPEAAVRGARVFAPRLVRAAPGE
GVSFSGRVLVTGGTGGLGAIIARHLTENHEISDLLLVSRRGLEAPGARELRADLERLGAT
VHVVACDVSDREAVAALLAAFPVDGVVHTAGVLDDGVLDAMTPERLDRVLAPKADAAWHL
HELAGDLTAFVLYSSASGVLGNPGQANYAAANNFLDGLAQFRRARGLPAVSLAWGLWGST
GGMGGELSAADATRLNANGIRPITPERGVALFDAALAAGTPVAVPVSLDLGVIRRRLDFV
PALLRTLVPSTRRRRPATAQSSLRRTLAALPEQEWPAAVLQVVRGQVASALGYATPAGVE
IGRAFSDLGFDSLSAVEFRNALAAVVGIKLSPTLIFDYPTPSALADFLLAELSGAAEESA
VAVAAVDDDPIVIVGMACRYPGGVVSPEGLWDLVADGVDGVTEFPTSRGWGSEVFDPVPG
TAGKSYVREGGFLHDADLFDPGFFGISPNEALVMDPQQRLLLEVSWEVFERAGIDPTTLR
GSDTGVFVGMMYHDYAANSSTGAVASGRLSYVLGLEGPSMTVDTACSSSLVSLHLAAQAL
RAGECSLAVVGGVAVMATPEVFVEFSRQGGLSRDGRCKSFAAGADGTAWGEGAGVLLVER
LSDAQRLGHRILAVVRGSAVNQDGASNGLTAPNGPSQRRVIRKALASAGLSTADVDVVEA
HGTGTVLGDPIEAQALLETYGQDRERPLLLGSIKSNIGHTQAAAGVAGVIKMVMAMRHGV
APRTLHLDEPSPHVDWTAGNIQLLSEAQEWVVDGRPRRAGISSFGISGTNAHVIIEQAEE
SPVTPGADDDGPVVVPLSARTPEALADLADRLGEVAASLRPVDLGFSVATSRAVFEQRAA
VVATSRASLGEALRTATASTARPGDLGVVFTGQGSQRLGMGRELHARFPVFAAAFDEVLA
GFTADVRKVVWGDDAEALNRTGFAQPALFAFEVALFRLFESWGIRPTVLGGHSIGELAAA
YVAGVWSLEDACRLVEARGRLMQALPAGGAMVALPVSADQLVLTPGVGIAALNGPTSTVI
SGVESEVLAIAEQFPNARRLKVSHAFHSPLMEPMLAEFAEIAGGVTYHQSSLPILTSGDV
TDPAFWVAHVRDAVRFTDTVAALVERGVGTVLEIGPDATLTTLIGYNTDELATIAGQHRD
AGETTAVATAAGRLFETGTAIDWTAFYAGRDTRRVDLPTYPFQRRRFWMDSLDYWREAWS
GAAAGLGSGDVSSAGLTAPDHPLLGAVVTLPSTGGVVLTGRLAVSAQPWLADHVVGGTIL
FPGTGFVELAVRAGDEVDCPFVEELTLIAPLALAGPDAAAQLRVTVMPTGEAGRHRVEVH
SRAEHGAAEWRLHAEAVLADRAPAAGFDLFQWPPAGAEPLDVTGLYPALAEAGLPYGAAF
RGLRAAWRQGADVLAEVAVEGAESGRYGLHPAVLDACLHAIALTEGSGETASLPFAWSGV
TLHAAGAAAVRVRVTPTAPGEGVRLQVADATGSPVATVDSLTLRPVDAAAMRTTGVDGLL
RLAWQPVVSGTAVPDDVVVLEAARFDPGPGVAVPVRVRAVLAGVLAKVREGDPLAVVTRH
AVAVADGDVVDVVQAPVWGLVRSAQAENPGRFVLVDTDGGDVAGALAGGAAEVAVRGGEV
FAPRLVRSGVGGDGSVFSGRVLVTGGTGGLGAVVARHLVDHHGITDLVLVSRRGVDAPGA
AELRADLELLGATVNVVACDVSDRDAVAALLDEFPVDGIVHTAGVLDDGVLGSMTPERLD
RVLAPKADAAWYLHELAGELSAFVVFSSAAGVFGNPGQANYAAANNFLDGLAQLRRAQGL
PALSLAWGLWGSADSGMGGDLSAADLGRMRRSGVVPLTEAKGLALFDAAVSTPAPVLVPL
GLDLSGADPLAVPELMQGLLRRRPSRTAVSAGASVWRSRLADLDEPGRLALMSDLVCAQA
ASVLGFASADAVDAGRAFSDLGFDSLSAVEFRNTLAAAVGIKLSPTLIFDYPTPSALADF
LLAELSGAAEESAVAVAAVDDDPIVIVGMACRYPGGVVSPEGLWDLVADGVDGVTEFPTS
RGWGSEVFDPVPGTAGKSYVREGGFLHDADLFDPGFFGISPNEALVMDPQQRLLLEVSWE
VFERAGIDPTTLRGSDTGVFVGMMYHDYAANSSTGAVASGRLSYVLGLEGPSMTVDTACS
SSLVSLHLAAQALRAGECSLAVVGGVAVMATPEVFVEFSRQGGLSRDGRCKSFAAGADGT
AWGEGAGVLLVERLSDAKRLGHRILAVVRGSAVNQDGASNGLTAPNGPSQRRVIRKALAS
AGLSTADVDVVEAHGTGTVLGDPIEAQALLETYGQDRPDDRPLLLGSIKSNIGHTQAAAG
VAGVIKMVMAMRHGVAPRTLHLDEPSPHVDWTAGNIQLLTEAQEWAVDGRPRRAGVSSFG
ISGTNAHVIIEQAEEPPVTPGTDDESPIVVPLSARTPDALAALAGRFADLLEADPAIRPL
DLAFSVGTKRAAFEQRTALSGADRAGLVARARRAAGGAPTPTPIRKGPVGVVFTGQGSQR
LGMGRELYTAFPVFAAALDEVLAGFTAEVREVMWGDDPAPLHETGFAQPALFAFEVALFR
LFESWGVRPGVVGGHSIGELAAAYVAGVWSLEDACRLVEARGRLMQALPAGGAMVALPVS
ADRVALTAGVGIAALNGPASTVISGVEAEVLAIAEQFPNARRLKVSHAFHSPLMEPMLAE
FAAVAAGLTYAKPAYPVLAAGDVTDPAFWVAHVRDAVRFTDTVAGLVERGVGTVLEIGPD
ATLTTLIGYNTDELATIAAQQRDTGELLATATAAGRLFETGAAIDWTAFYAGRDARAVEL
PTYPFQRQRFWLDALDYWKEAWSGAAAGLGSGDVSSAGLTAPDHPLLGAVVVLPDDEGVV
LTGRLAVSAQPWLADHVVGGTILFPGTGFVELAVRAGDEVGCPTVEELTLVAPLALTGPD
AGAQLRVVVSPADASGRRRVRVHSRPEHSAGEWQLHAEATLTEETAPAGFDLLQWPPTGA
EPVDLTGGYPALAEAGYGYGPAFQGLRAAWRRGDEIFAEVATDEADADRYTLHPALLDAA
LHAVLLTHADGDGDGRIVLPFAWSGVQAFADGGPATIRVRISPAGTGDDLTIRVADRAGR
PMLTVAALTSRPVDPAAMRAADVDGLLRLSWQAVAPGTAVAEDIVVLEAARFDPGPGVAV
PVRVRAVLDAVLARLQEGEPSVVVTRHAVAVADGDVVDVVQAPVWGLVRSAQAENPGRFV
LVDTDGGDVAAALAGGEAEVAIRGSELFAPRLVRSTVTAGGPAFAGRVLVTGGTGGLGAV
VARHLVDQHGIVDLLLVSRRGPDAPGAAELRTDLERLGATVNVVACDVSDRDAVAGLLEE
FPVDGVVHTAGVLDDGVLASMTPERLDRVLAPKADAAWHLHELAGELSAFVVFSSAAGVF
GNPGQANYAAANNFLDGLAQLRRAQGLPAVSMAWGLWGSTGGGMGGELSPADVARMRRGG
VVPLTGAKGLALFDAAVSTPAPVLVPLGLDLDGADPQLVPPLLQGLLRRRPARSAGAAGT
PDGAEWRARLAGLDRPDRLALLLTLVRGQAATVLGFASADAVDAGRAFSDLGFDSLSAVE
FRNALTAAAGIRLSPTLIFDYPTPAALAEHLLSHFADGPETDGGEAEVRQVLRDIPLSRL
RDAGLLDALLELGGVRVAAAESPEPAETLSIDEMDTESLISRALEDFDFGDTTQGA
>A0A099KD01|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Colwellia psychrerythraea|TrEMBL
ELQDLEYDVHAVPIGQPINNIKFYVLYNGQPIPLGAIGELYIGGDGVTHGYLNNDELTND
KFVKNSQQTDQDDIIYRTGDLVRYRHDGNLEFIGRIDDQLKVRGYRIEVGEIEAQLVSHD
KIKEAVVLAKGEGIKKHLVAYYTINQHAPKISELKGWLKVSLAEYMIPTKFIEVDKFILT
NNGKVDKKSLSEIAYVELGHNDKFSKNNNIEDQLSVIWCEILQLDNISINDNFFESGGNS
LLSVEVQKAVSDRTGYQIELTDIFEYPTIKSLSGYLTKENELDERAVNTDSANTNSANTR
RQQDTDIAVIGMSGRFPGADNIDEFWGNISAGVESIQFFDDNELLESGIDLTTLQQKNYV
KSGHILNGMKDFDANYFSFSPRDAELLDPQQRLILETASQALEHGGYGDRLQKRNVGVFV
GVGESQYLLKNILSNPDIIGTAVKTAFYGNSSAYTSTRLSYKLNLTGPSINVLTACSTSL
VTVHQACNSLMLDECEMAIAGGACVSLLKPTGYLYEEGGISSIDGHCRPFDNNAQGTRGG
SGVAIVLLKRLDKALEDKDTIHAIIKGTAVNNDGADKVGFTAPGLGGQADVISKALLNAD
VSATTIQYVEAHGTGTVIGDPIEFKALQKAYCTSENRSCALGAVKANIGHLDTAAGVAGM
IKVIQSLKNKQIPPSINFDESNSQINFNNSPFYINTELKPWDNEDNLRRAGLSSFGIGGT
NAHVIFEQAPNVESSTSLRDTWLLPLSAMTKTALNTACENLRTFLQENKDVSLHDVAYTL
QVGRTKHEYSTALACKSVAEAISLLTNKQKVVRDKGKSRSVVFMFPGQGAQYINMGQQLY
LEEPLFKALFDQCADLLLSILDEDLRSIIYPQGDSNPDNEYNKTLLELTRITQPALFVIE
YCLAKLLQSWGIEPDAMLGHSIGEYVAACLAGVFDLEDAIKLVSARGRLMQQVESGTMLS
VSITAEQLKPLLVQTGTCLAGINSVSNCIASGKHEAITRLTVLLDELQIVYRPLHTSHAY
HSKMMDVILDDFKAVIEKVSLRSPTLPYVSNVTGRFITSDQAQDPQYWVDHLRGTVLFAD
GVDTILSDREFLHANKVVIEVGPGITLSTLARKNIQAREHATVSTMRHPNESICDLVNLQ
NALGKLWGYGVNVNWQAFHQEHLGRRVPLPTYPFERVRYWIEPVENNQRMIMNTETKLPM
DKWWSVPTWKQKPGFKKDKLLINSQSSAWLLIMDDAGVGEGVAECLLNAGHRVIRAYSGK
CFARVSNNEYTFDISQEADYLALIRAASSAAEITRVVHLLSIDPMSQRHEYDMGDFWSDQ
KNGTLSALYTIKGMIIAGLCGDIMIDFITNDIERVSGEEIINPGKATITSLCKVAPQEYS
ELECHHIDVKLHQYHDNKYIESLSQTIARELVMQHRCSMIALRGNQRWEKQYETDVFKQD
MPAAQVLKNDGVYLITGGLGNIGLLLAGYISKTVKNAKLILVGRSDFPARDDWKDIIKSQ
VDQSICKKIDKIQTIQARGTDVVIHSADTADGMQMQTLFETVEERCGVINGIIHCAGQVH
GSMKALIETEKQDFEKQYRSKVNSVIVLDELLRTRQPDFCLLMSSLASVLGGLGFSAYAA
TNIFMDAFVQRKHDLGDDNWISVNWDSWNFSSAQAGDSGYNNFAMTPEEGEQAFKQVLAG
AYYPQLIHSTGSLDHRLSQWIAKTETTTQTLYERPDLETDYVKPTNEVEEILVAIWQNVL
GIEQIGIQDHFFDLGGDSLIATRVISAIRKTLSVNESLFSIRDFFENPIIELMAKKISIN
MSNNNINTRKAEFFDAGKSVEEGVF
>V4ZAM1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii (strain ATCC 50861 / VEG)|TrEMBL
MTEAATPQNVTSPADLSKQNVSFRPGVNAVEFVSGYSHAGSVVCSLPSPIFFNKASSSNG
NCESNASTASSSAALGTEASSNVRTGTVLIFDCGSGNTWQHLRQWLSDEGASHIVVVHAC
AEEGADRLGVKTLHPSRVNGGQGCSQTLIKEVKCRPHHPEEVVELFKLLKEGLHFPLVRG
IFYILGEKLDSLLANQTTSSVHDMMKTASGAWSIHHALGQLGMEADLDFFIFFSSISALF
GSISQSISAAVHASLDALAYYRRHLGLAATSIQWAPWADGSSATSPQIVRHWLEKGGVSS
VRNPLAAVSAILKNHTAIGAVVACFHADPTIMHEMGETDQECTFLSSGPAANTRDSTSGN
VKVRTNPVKSRVFQNVSPSTDTCGENHKDELLVILTQLVRREVIEIASCYVFFEGNNLST
DESLVDLGLDSLSAVELRHTLQQRFCVNIEPTFLQANATIDSISALLVTHVATSLTGALP
VLPLSCPGLASAVDDCALVSLALRLPGRCDSLDAFWASLQSDSGYCRPGASEACDQCFMH
RAGSGELPAESQSIGTNLDARKGFCWLSNRDAFDSHFFGISFTEALATDPCHRLLLEATY
EALCKLNTEQQSGTSGTPIAVFATSSSTQMRASLPSYTKPASSQNTQDNNGCLAASFLSY
HLNLTGLAVPIDGSDSASLIALDLGREHLRGTDSVCQAVVVAAGSLLPICSHGWPSACTS
PTIRRFRGRDDHAFPDRETYAVPRGEGIVSVVLQRLSVARENGNSPMAILKGISLIRMGR
GERPIPSQWRTADVKLRRKTIVEALKMSRVEPRTVAVLETDGLTGSQAEDAYTVEAMADI
FGPRHLAESCSPLVIGNASLHIGQAREASGLATLAKLVLMLERGYAPPIPRLRRLHPDVK
RGILPSGFVMFPCKKMDLLAFRQHPDHVYGPNEKRDQKEGRPLIGCVSSLGSDKTSGCFI
VESSPRLHGRTSDTRVSLERAVPLAGTKDACSHNYLHVRSTDGSESEIRGDDRAVWLFCD
DLWGLQSVGRGLYCSDPAFAALLEQAERVLGNRIPQPLSCLLYPSTTAEFQKAEDALAFP
RIAAFVLFSLQWALATCLRHQEGEPTAVMGLGVGEIAAAAVAGILSLEDAVELLELLSSE
TRTCDYRNKPMPGGNVNSGGLFDRGNSGTGGCGVAQDCKSPWVLCGLNKTPTSESAALEF
SVLESRRGSSSRISSETPTSNTTPHNRDVFQERFSRKPRRATCPSPIIRHAWEKVAHGNP
ENDEEAELECPSSQSRRANCPSPAIQHACEETAHGNHANDGEADLLMDVFRFRPEPSEPL
GQVTARIALRNATCLFISTVSGRLATDTLIRAAEYWDPLVPKTQRVHRAVETAVQVAKTA
KLVCIGCSAQDGVHLSVGLPSVHPISPSPLRIFCFTGSSPSPQLLAPCESASGSSPRVAV
VEHHGADSNLGGGAPWWKHLLFRLPQLEGFPSGCSASTRLLADRLVADVPTPDNHMINNP
QTAAVQGAGETLGTLREGSSGEGEDGEKGYRSESVNTQHPVYKVYRRCSEPELHESELSL
LCSDTVCQPSLEKTVELFIGTGLEQQGKLSTVSSSWLVFSDIVAPSPISLYSTLAFQNED
GEQRFCTLNVASQVATVYAEKVKTQVCSIIIECKRGFKPPREIARCHFVKNQTAVGKHEP
AVSSLSRIRWLPATKLPEGWLRTRRPHVWPCKIKVTKAACPLPTRRVDLQEIYWGKRHIL
CRFRMPRNPPRDGVEKSTQLIAILARLVTVSVGVAATCVLHETETSGRYSHSHPGPQVED
DQKTHMDALWVCPYVPFSECWCVIRHRRNGSSIKEGKGRDWETCDVEIFSENGTAVAVVL
GFGIQSHALSMRMMEGRGNDGDSSVSTTVCVA
>I8TU35|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pelosinus fermentans JBW45|TrEMBL
MGKSKVFMFSGQGSQYYHMGRELYETNLTFQHWMSKMNQIIQQNAGINILEEIYNPAIHR
STVFDKLSYTHPAIFMVEYSLARVCIENGIEPDYVLGASLGEFVSAAITGILSLEKALEC
LLIQSALIQSDCQPGSMTAIVHNPELYKQTSIIHDHFELAAINYSSHFIISGNYRDELIT
VEAYLKREGIVFQTLPVRYGFHSANIEPIAREYKKKLSNLTFNHPQIPFISCVSAGSIDD
IDSEHFWNVLRQPIDFQKTIQRLEAGNQFVYIDLGPSGTLANFVKRNLTSDSESKVYTIL
TPFGQDVRTLQKVMESLN
>D3D0B9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. EUN1f|TrEMBL
MPEAPALTDAPAGTDTGATVVPSAVPPGIADVQTLLRAGDPVLRDHRRHGVPTLPAAAYL
DAIYRSAGASGRRTAQVELRDVRFVEPLSGTDGVDHRLLLRCRPDGGGQRMRITSRADAV
PGGAAPVGAVPVGAVPVDAAAVGAVPAGGETLRVVCAVLPADSGARPGPLALDEVRRVLA
GADSVALDTVYDRLAGAGVDYEGFMRAGGACARVGERVLAEVRLGAAALGRSDGFLLHPA
LLEAAIVVTVAGSAGFAGSAGFAGSAGFGEPAATAAAGGVRPGLTPLAGIDRVRIWVAAG
ADRPDALTTVYVDARPAGGRGGQARLTLYDTAGTPVASVEGLAFGPPGGSAHLAGAPERN
GTAPRRDPSDQGGAGRAQPPRWPSQRSQPSQPSQPSHPGPTGPGWQQAPSERPGRARAGG
FEIAVVGMSGRYPDAADLDEFWRNLERGHHASGAVPPSRWRVGDYPTAGSSPHGVGAFLT
DAEAFDPRFFRIPPSAATAMDPQERLFLQTAYAAVEHAGHVPADLAAPRGTTGVFVGASW
TDYRLRGVEATLRGAPQTVTSGLSSIANRVSYALGLTGPSLTVDTACSSSLAALHLACQA
LLLGECDAALVGGVNLVLHPDKFALLDRMNLPSSDGRCRSFGAGGDGYQPGEGVGALLLR
PLSAALADRDTVYGIIRGTAVGHGGTGAGYLVPQPAAQADVIRRAWERAEVDPATAGYVE
AHGTGTALGDPVEVAGLRLVLDAAGPRAAPCALGSVKSNIGHLEPAAGMAALTKTLLQLR
HGVIVPSLHSDVPNPDMDLGAVLEVPQQRLAWPRLRGADGELPRRAGVSSFGAGGTNAHA
VLEEYPEQPDPGAPTVMPGGAASDVAGPGMAGPAGPEVVVLSAATEERLRVHAARIAGHL
RQVAAAGSVPFADLARTLQVGRPALPARLALVASGPAEAAERLSAFLGGAGDADGAGGGG
EVFTGRAGEPIADGGETDVIADSYRRGDLTDVARRWAGGGAVDWAAVNGGPGRRRALPGY
PFETSRFWIDLGARTGHPDSPVPGRCAPERSAPENSVPEHAPEQRRRPAVMTFLDAACEP
FEAGLAPVAEELEAAYPMLGAHAAGAVLRRLRGMGLPADGATAPELRRLLGVPDRFERFL
DVCLRVLRRHGLLYERDGLLHPAGLADDIDLQRAELLARHPQVAPFLRLLDVCLDAYPDV
LRGVRPATEVLFPGASMDLMAGIYRGNRVYDFYSSLVARFVAAAARARTADSGPAAGSGS
GGRRPVRILEIGAGTGGTSHQVLAALAPLAASGVELEYHYTDIGGSFVAHGRRTFGAEHP
FARFRVLDIENDPAAQGFELGAFDVVLAVGALHAVADIDAAMRRVRALLADDGLLVLGEA
VENHDIMAFTIGLLDGWHLYRDPQHRLPDSPLLSVDGWRASALRTGFGELRAYGEGLTAD
PSSSHRLLVIPAGAVTGRAPSPGRGAEDVQAQPDPDAVERAVAEIVADELGVPVAEVRPT
ASFAEYGVDSILAVRIVERINSSLAVDIHATVIFDHPSVRALAAFALAQGGRPEPAAAEP
ATARPAPPPAPAPPPVPAIPPFPSPPPVPAHPTTAVPAPSPAAAAGPRASVAASGTSVAA
GRGGDTGVVDIAVIGLSARYPGAADYREFWRNLVTGHDAITEIPPGRWNLADHFQPWPPA
PGRTYSRWGGQIADVDRFDPLFFGIVPAEAELMDPQQRVFLQESWNAIEDAGLDARQLRR
SRTGVFVGAPPSDYLQLIRDRGYFGSPHVFTGNSPAILPARVAYHLDLTGPTVGVDTACS
SSLVALHQACQSLAAGECELALAGGVTVFATIEHHLLTSSIGMLSPTGRCRPFDTAADGI
VMSEGVGVMVLKPLTRALADGDPIHGVIKGTGVNQDGRTNGITAPSARSQTELLVEVYRR
FGIDPATIGYVETHGTGTRLGDPIEIEALNAAFRTAGGGRLGGTPEPRPGVATVPIGSVK
SNIGHTSHAAGVAGVIKVLLALSERRIPPSLHFDQANELIDFSATPFFVNTELLPWEAPQ
PRRGVVSSFGFSGTNAHVVLEEHRETRPPTRAPFARPSDPALVLLSAATEDSLRDGARQL
LRFLDGTPSVALADLAATTQLGRASHEHRLAVRAGSVARLRAELEQAARGSTGPDSVRGR
VDPDRPVPPAERLTSGADPAVVAAAWADGAAYDFAGLYQGTLPRRTHLPGYAFARERCWI
PSADDPNHPAPGLRPQSAEPVSGPVPGPASVPVGGVPSELVWPVVLDLAGTELGLAGDQL
DREASSADLGFDGPGRARLAGRLGEALGLDLPPGVLTVRTSLRQLVDTIVSGEWNRTAPA
PVPAPVPAAAAAATVAAGADVPASTRGPVPPRDVTALTVLAERFLLDVLAAEARIPADRI
RPKAPLQDYGIESVLIARLMSRLEAVLGPLPSTLFFEHQTISAVAAHLATSRADQLVAAF
VPPEPDLPGSDARAGAAPTGSAAPTGAAAPTGAAVVAPVMPTPVATVARRPEPMRSAVAA
HPARPAIVDRPDDIAVVGMAGRYPGAADNQAFWANLLAGRDCITEVPPQRWDHSRYLSTN
QDEPGATYARWGGFLDDVDRFDARFFGIAPRDADLMDPQQRLFLEVAWAAMEDAGSPPER
IRRAARRRGKRDAAVYVGVTYGEYQAVAGAPVAPYWAVANRVSYHCGFDGPSMAVDTACS
SSLTALHLACESLRRGESAYALAGGVNVTIHPGKYLLLGSGRWASTDGRCRTFGAGGDGY
VPGEGVVALLLRPLADAREDGDRIYGVIRATAVNQDGRTNGFTVPNPVAQAALVRDALAK
ADVDPRALSYVEAHGTGTALGDPIEVSALTAAFREGTDDRGYCAIGSVKSAIGHLEAAAG
LAGVAKTLLQLHHETIAPTLHADPPNPHIDFAGSPFTVARDARPWPRAATGQPRLAAVSS
FGAGGSNAHVILGDPVTGPDGLGSGQHPAGAGSPWTGPTPVLLSARDPQRLREQATKLAA
LLGSPEGRRHPLVDIAWTLMVGRESFEHRLALVAGTHQEAAEAIEAFVAGTPDGRVRTGV
VAAHVDHGGDSEPDRAYLRSLREAGHTHRLAELWTQGWTIDWEQIWAPLRGRVVSLPTYP
FAADRHWVEGDEFRRSGTPGQVSAPAQVSAPDRIPAPDRIPAPDRIPAPGQIPAPAQIPA
QPHSQAQTQAQTPVRNPASPLTEGRTPTPTPIVGRGDDEVRQDLVVQVKAIFADLTRYPV
DELTEDTNFLDYGFDSVVVVRMLNRVMKHYGVRIPGTLIEECTTIGSFVDHVVAGGYIAG
NDVGGAAADEMTRILTAPALRPAKVIRPEPFPVESVFVTGVTGVLGGRLLYDLLTETSAR
ITCLVRGRDEQAARERVQYFLQVYDQEQLLVDEFAHRVSVVLGDVSQDNLGLSAAALDEL
TAHVDVTIHVAARTTLVTFYDSLSAVNVDGVQRIIDFSLRTRHRYLVHVSSFSALGDWQL
DANRPFTEDDLELGQGYDHLPYQETKYHAEKLIRAASERGLVWNIFRPGNIMGTGDTGRY
PFREVTVKGVYYDLIRTAVDTGYYLDASTYWDISPVDYVSTGLLHLALRRPSYRETYHLT
NPDICSLGEVYRMIREHGYDIAPLSVDEYHRHAVEALFRPGASTNGSANGTANGTAEPYA
SQMIEMVKYGVETWGPEHYDRSTYADSTYTRNLLGAAGINCPTIGDLVTRYLEHCADVGY
IPPPNRPAPARRPALAEEGR
>A0A100JUB8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces scabiei|TrEMBL
MSDRTEQKLRDYLNRVTIDLQQTRRRLRDVEERSREPIAVVAMSCHFPGGVHSPEDLWAL
VADGRDTYSGIPADRGWDTTGLAGSGAPVTGAFLDEAGGFDPAFFGISPREALAMDPQQR
LMLQTCWEAVERGGIDPVSLRGSRTGVFAASIDQGYMSLADGAPEGVQGFLMTGNAISVM
SGRVSYVMGLEGPSVTVDTACSASLVALHLAAQSLRNDECSLALVGGVNVMALPGAYVEI
SRQGGLAGDGRAKPFAAAADGTGWGEGVGVLLVERLSDARANGHPVLAVLRGSAINQDGA
SNGLTAPNGPSQQRVIRAALADAQLAPADVDAVEAHGTGTRLGDPIEADALLAAYGQDRT
EDRPLWLGSIKSNIGHTQAAAGLAGVIKVVMAIRHGVLPQTLHVDAPTPHVDWSSGGVRL
LTERRDWPVADRPRRAGVSSFGMSGTNAHVIIEQAPEAEQRPADEQAPEGGRQGAAEPIA
GAGPLTAPDAGSGLASGPSSRAEPDVDPLPTVPWPLSGRSPEALRDQAARLASWLADRPG
LRPADVGHSLAATRSAFEHRAVVVADRPEGFLRGLAAVAAGTSAAETVTGRTGAGDGRTV
FVFPGQGSQWAGMARRLLDESPVFAARMAECEQALAPHLDWSLSAVVRGEPDAASLDRID
VVQPVLFAVMVSLAAVWRSYGVEPDAVVGHSQGEIAAAYVAGALSLDDAARIVAVRSRAQ
LELAGTGGMASVSLPADTLRDRLRAWEGRLSVAAVNGPASAVVSGDPEALDEFLRQCEER
EVRTRRVAVDVAGHSAHMDRLRDGLLDVLAGVRPTAATIPFCSTVTGGSLDTTGLDADYW
FRNMRQTVEFDAAVRDLVRRGHSVFVEISPHPVLTVPTQDTLDDLADPDAAVPAPPTLVT
GTLRRDEGGLHRVLTALAQVHAHGVPVDWAAVFAGHRPERVELPTYAFQNRRFWLEPQTR
PGTAPETTDPADAAFWAAVEREDVAAVAATLGVEAASWSEVLPALSAWRRDRRDRAVLDG
WRYHISWQRLTAKAAAPLRGRWPVLVPDGHTADAVVTRAVEALRERGADPELVVLDHTHT
DRSRLTDHLRELLATGGTETAPAGVLSLLALDERPHEGLPALPVGLALTTALVQALDDLG
VRTTLWCVTSGAVPVHPSEPVPHPVQALVWGFGRTAALEHPNLWGGLIDLPEQCDARAGQ
LLVDLLAGAGDEDQLAVRSSGAHTRRLVRATASTPSTPAPSAPWRPSGTVLVTGGTGGLG
AHAARWLARGGADHLVLVSRRGADAPGADELAAELTALGTGVTLAACDITDREALAALVD
RAAAEGHPVRAVLHTAAAAQLFPVRDENPASMAATLAAKVQGAANLDAVLADTDLDAFVL
YSSVSGVWGSADHAAYAAGNAYLDALAAHRRGRGLAATSVVWGIWSAEGGGLATSDLERA
LLERGIPFMDPRLAVGGLQRVLDDDETVVVVADVDWARFVPVFTSVRPSPLIADLPDVRA
LATAEDRTDPDPDDTDGASALRRTLAGLAEPEVRRTLLELVRTNAAAVLGHESADAVLPD
RAFRELGFDSLIAVELRNRLNQVTGLRLRATVVFDYSCAALLAEHLRTELLGDTAPAAAT
TAVVPVADPDEPIAIVAMSCRFPGGIDTPERLWQLLIDGGEVLSGMPADRGWPLDRLYHP
DPDHQGTSYVREGSFLHDAGDFDPAFFGISPREAVAMDPQQRLLLETSWEAFERAGIDPA
SLRTTPTGVFAGVNYQDYTSLAGSSPEGGEGHLVAGGAASVVSGRVAYTLGLEGPAVTVD
TACSSSLVATHLAAQALRGGDCSLALAGGVAVMATPGVFVGFSRQRGLAADGRCKAFGAS
ADGMGLAEGVGVVLLERLSDARRNGHPVLAVLRGSAVNQDGASNGLSAPNGLAQQRVIRQ
ALTNAGLTAADVDVVEAHGTGTTLGDPIEADALLATYGQDRPHGRPLRLGALKSNIGHTQ
AASGVAGMIKTVLSLRHGVLPRTLHADEPSPHVDWASGEVELLTEARDWPDTGAPRRAGI
SSFGFSGTNVHAILEQAPPASEETEAGTEPEPGPRDLPWVLSAKSSQALAHQARRLRDRL
ADADAPGPLDTGYSLATGRTPFEHRAVLLGTEGGAPSAALDGLAVGEDVPGLIRGTADTD
GRRVFVFPGQGAQWAGMAMELLDTSPVFAASVAACEQALTPYVDWSLDAVLRGAPDTPPF
ERVDVVQPALWAVMVSLAALWRSWGVEPDAVLGHSQGEIAAAVVAGALSLDDGAKVVALR
SRAILALAGHGGMVSVAVPRERGVELVARWSGRLSLAAVNGPSAVVVSGDAEALRELIAH
CEETGVRARTIAVDYASHSAHVERIRDELSEVLAGIEPVAGQVPLFSTLTGDWLDTTTMD
AGYWYRNLRETVEFDGAVRALADQRHQVFVEVSPHPVLTMSVEDTLEAAEAPQTVVTGTL
RRDEGGLGRALTSAAELWVRGVPVQWPVLFEGTGARRADLPTYPFEHKRYWLQGADPTAR
AVVEDEADSEFWRIVERGDAEEAAGNLAVDAETLGTVLPALNAWRRRQRDGAAVDNWRYR
VDWQPVTDPPAAALSGTWLVVLPEGHADDQLVRDALLTVTEAGAEAVTVLLADTDVDRAG
LADRLAAALDGRTPQGALSLLAVAGHPHPDHPAVSAGSALTLVLVQALGDLGVEAPLWCA
THGAVATGDTDTLTAPDQALIWGTGMVAALEHPTRWGGLVDLPTALNSRSRDRLRTILAG
ATGEDQLAVRSTGLLARRLVRAPRLPGNRPAWKPRGTVLVTGGTGALGPHVARWLAQGGA
EHLVLPGRRGADVPGADELRAELAELGTELSLPACDFADRDQIAALLAGLEERGTPVTAV
FHAAAYIQLASLDDTPLDAFAEVVAAKADGARHLDELLDHELDAFVMFSSIAGVWGSSNH
AAYTAGNAYLDALAEHRRARGLSATTVDWGVWSAANPWTVRDTVDDSDFYRVQKQGLPLI
EPDLALTGLQQALDDDETVIALANVDWEQFADVFGSVRPSRLLTGVPEARRQLEEAAAPG
TDATPAANVLRERLDGLAEPEQRRVTLDLVRTHAAAVLGHDSPQELRPGKAFQELGFDSL
TAVELRNRLRTATGLRLPATLVFDYPSSAVLAEHIRAEVLGERQTPAALEPASGGTVAAD
EPIAIVAMSCRFPGGVHTPEQLWTLLEEGGDVVSEFPTDRGWPLESMFDPDPDQPGTSYV
RHGGFLYDAGEFDADFFGISPREAVSMDPQQRLLLETSWETFERAGIDPDRLRGSDTGVF
TGVNYQDYGASVAQTGENEGHLLTGSAASVISGRISYTLGLEGPAVTVDTACSASLVAVH
LAAQALRAGDCSLALAGGVAVMSSPGAIISFARQRGLAADGRCKAFSDAADGMGMAEGVG
VILLERLSEAQRHGHPVLAVLRGSAVNQDGASNGLTAPNGPSQQRVIRAALANARLSAAD
IDVVETHGTGTRLGDPIEAQALLATYGRERSDGRPLLIGSLKSNIGHTQAAAGVAGVIKT
VLALGHGQVPRTLHVDRPSTQVDWTAGAVDVVTDATPWPATGRPRRAGISAFGMSGTNVH
AILEEAPEKAPEESPQETPDEAPARTVAWPLSAKSPDALRGQAERLTAHLADTPGLPPAD
VGRALTTRTAFEHRAVLVGDGTRLPAALTALADDGTAPDLVRGVAGTVGRTIFVFPGQGS
QWAGMAGELLDESPVFAARMEECERALAPFVDWSLLDAVRSGGAWDRVDVVQPALFAVMV
SLAEVWRSFGVVPDAVVGHSQGEIAAAVVAGALSLEDAAQVVALRSKTLDALAGRGGMAS
LSLPADQAEAALAPWAGALSVAALNGPATTVVAGDAEALAALLAQCEAQGVRARRIDVDY
ASHSEHVEEIHGILMDALAGIKPLPSEVPLYSTVDGAWLDTTGMHAGYWYRNLRQTVGFD
PAVRVLAAEGFTSFVEVSPHPVLTMAIEETVETAGREAVVLGTLRRDEGGLRRVLLSAAE
LWVRGGAVDWTAAFPGESTAELPTYAFQRRRYWIQPPAATPRGPGATGHPLLGTAVEVAD
TGDLVLTGSLSTRTHPWLADHAVSGVVLLPGTGFVELAVRAGDEADCPRVEELTLQAPLV
FDRDAAVRIQVRVGAPDDSGRRTLGVFSRGEDGAGAPWTGHATGVLAPAGSTDLAAHPYG
AAWPPAGAEPVPVDGLYERFADAGYGYGPAFHGLRAAWRLGQDVYVEVRLPEDQHTGAAG
FGLHPALLDAALHGLWLAAPDGADQSDAPGTARLPFSWEGVRLHASGATELRVRLSYDDT
GSVALAAADPAGRPVADVAALAIRPIAVDALRGAAAQGRDSLFRLDWTALPATTEPPVGR
WAALGTGQPLPETHANLDALTAAVDGGAAVPDVVVTLCPPGGNTADAARTALAGTLSLLQ
TWLADDRWSDTRLVLVTRGGVATAPGEDIGDLAAAAVWGLVRSAQSEHPDRFVLVDADDP
AEALKALPAALSATEPQLAVRDGRTLAPRLTRTPPPDAEAGAGKPWDPEGTVLVTGAFGV
LGGLVARHLVTEHGARHLLLTGRRGADTPDAVALVDELTALGARVETAACDTADRDALAG
LLAGVPDTHPLTAVVHSAGVLDDGVIGSLTPERLDRVLRPKADAALHLHELTRDLPLAAF
VLFSSASGTVGSSGQGNYAAANAFLDALAQHRRARGLPGQSIAWGMWAERSALTGTLDEV
DLRRMARGGVGALTSDEGLALFDAALERDDAVLVPVRLDLARLRARAGTGPVPALFRALV
RGAARRTAATGGAADAADTLRGRLAGLAADDARAVLADLVCAHAADVLGHAGASAVDPER
AFRQLGFDSLTAVELRNRLNAATGLRLPATLVFDYPSPAAVAGYCAERLAPAGSPQIPAA
APADADITRALSTIPPARLRESGLLDALLKLAGPDPRGGEPQTAGSESGIQEMDVDDLVR
LALGSERD
>A0A0N1G573|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
SAVNQDGASNGLTAPNGPAQQRVIRQALATAGLSPHDVDAVEGHGTGTTLGDPIEAQAIQ
KVYGSGRPEDRPLWLGSLKSNIGHTQAAAGVAGVIKVVQAMRHGVLPRTLHVDEPSPDVD
WASGGVRLLTEERRWEAAGRPLRAGVSSFGVSGTNAHVILEQPEPVGAPVPGTAPTDGRP
LPWAVSGRTPAALSAQAARLLALVDPARGASAAAGVAHALLTGRSHFEHRAVVVAAAPDA
LTEGLGALVRGEPSGNLVQGVAADGVKTAFVFPGHGSQWAGMAQGLLDSSPVFADRIEDC
VRALAPHVDWLLVDVLREAPGAPTLERLDVAQPALWAVLVALAAQWEAYGVRPDAVVGHR
QGEVAAACVAGILSLEDAARIVVERSRVLASLAGKGGMASLALPLAEAERRIEAWPGRLS
VATVNGPSAVVVAGDEAALEELLAGCAERGERARRIRAATVAGHSPVIEEAREELLERLA
FVTPRRGRVPFHSTVTAALADPAELDGGYWYRNIRQTVRFAPVVRDLVEARYTVFVEVSP
HPVLAGSIQDTVEEADAADVVVTETLRRDHGGLDRFLASAAVLHARGVPVDWSPAFRGLE
PTRVELPTYAFQRRRFWLDGAAAPAGPLPRAGNDLVEDDLDGTNPGPAGTLLSRLGALGP
AARAEALLDLVRRQTADVLGHDGPEEVGAERAFKELGLESLTAVDLRNRLATAVGRRLPA
TLVFDHPTPGAVARHLATLLPAGPETGHGTAREALALLEQVVPDVTATDPDGLELIARLR
ELVTRWGGETTGPGGGDEIDLESATDEELFELMDSEA
>A0A3S4PTB4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Achromobacter spanius|TrEMBL
MAKRVAVIGLSFRFPSTTTDNYWAALLDGRDLITQVAEDRWCRDAYLHPAKDHPGSSYTF
AAGSIGDVSGFDADFFGISPREAAFMDPQQRLLLEMSWEAMEQAGVRPSSLRGSNCGVYI
GIASSDYAYRLADDANAIDASMATGNTASIAANRLSYFFDLRGPSIAMDTACSSSLVAFH
QACRAIVSGECSQALAGGISLHLHPYGFVTFSKASMLSPQGRCNVFDAAGDGYVRSEGGG
VFLLKDHDLALADGDNILAIVAGSAVNTDGRKSGLTVPSADAQANLMRQAYQQAGISPSD
IDYLEAHGTGTAVGDPIETRAIGVALAQQRGKDAPLPIGSVKSNLGHLEAASGVAGLVKA
IHVLRHRVVPATIGIQRLNPKIEVREWNLDIVTQNRKLRPTGRLIVGVNSFGFGGANAHV
ILESPPLRDPSAESKMAKTAAIPVMISGKSPQALKAAARQMADALRHQPTRFLYDAAYQA
AIRRDWHGERAVVFGTQCNAVADLLQQFADNAESTHEVVAGTALESARGPVMVYSGNGSQ
WANMGRRLLSDPVFAAAIDEVDALFSQYADFSLHKELAGENGDDRYQRTEIAQPALFALQ
VGITRMLAQRGVVPRAVIGHSVGEAAAAWACGAMSLADAVCLIFQRSRLQGQTKGLGSMT
AVGLSGEEAQALIALHRLGGSVCVAAYNSHRGATVAGMPAALSVLETVLAEQTISFRRLD
LDYAFHSPAMDGIEADVRSALARIRPRTSDVPFYSTVTGAILDGAALTADYWWRNVREPV
RFEQAAKQLVAEGNNIFIEVGPHPLLRSYLNDTLKTADMHGRVLSTSTRGGDDAEKVWIA
AGQVIVSGGQIDYSSLFPWEGPSVDLPTYPWQRERHWHPTTEESLGLLTRHVTHPLLGYA
MPQHEYTWQNQLDTQSHPLLADHVVGGAVVFPGTGFAEIALAAVLHWQAGNYAEIEDLEI
HAPLLLNASPSKLTRLLLDDADGRFRITAKDANSPSPWVKHASGRLLCEAGAARLTQDTL
VLPCSVPDFTASMHEALTRSVGLDYGPAYRAVSHGWIEPGNSVLAVLKPDACLSAELSTT
HLHPALLDCSFQLIIQLLRDDPAMGQGIAFVPARIGRLTLLANAGQPAAARVRLERRAPH
SLTASFELYNAAGEQIAAVEQARFRSIRLRKPAFANLCFLDVVAIPRPLAPAGPNPFDHA
SLRTALADAVAACVDEGAHSRYALEVDPLLDSLCDGFALDALRQLAPDGKLLPQTLITEL
RRCAPDAARLLDHTISRLTSAGYAQVSAAGVLMPAQNDNQGTSLDIWNTLMRDYPDYTRI
IHAIGRVGLHLPALLRGDVTLDEVCPVASTPALVTRTAIGPAGAQHLGAALCRAVDQAQA
KRMAGQRVAIIEVGQAAPLFSSRICDTLDANVADYCYASDHTEVLEQVLRQQAGRQPNAH
IEHIGQEGVTATPCYNLAIFHCEFDTLEAARAALRHARSSLRPDGVLILVGAHPAAWGDF
VFGGRQNWWQASNNGQLLSTQQPAEFWRDELQSLGLHCDSPLAFSPSIETGAYLLTARLN
EADNTNAAINVAMEPADWLILADRKPDALAHSLQAALTAAGHHVRLAAGVAPEALDDLLR
HGTIGPTHHVVHLSGLAWADTQDTHQELLARQTHRCAMAAAAIQACERTQTGATLWLITA
NAAQDPLATTSLPRAMHTLNDAALWGYGRTLANEASNFRVRLVDIPLAQSTELVDALARE
LNAQDDEDEIILDGAGARYAPRLRHATYPKTVQRGPTGPQAVRLGFEFPGQLRNLRWESC
AAPAPGDDELEVRIEATGLNFRDVMYALGLLSDEAIENGFAGPTLGLEFSGTVIHVGSRV
DGYAIGDAVVGFGPASFGDRVLTKPTAISHIPEGFSFEAAATIPSTFFTVYYALHHLARL
EEGEKILIHGAAGGVGIAAIQFAQWRGAEIYATAGSDEKRDLLRLLGVRHIYDSRSLSYA
DEILADTDGCGVDVVLNSLAGEAINRNLRVLKPFGRFLELGKRDFYENTRIGLRPFRNNI
SYFGIDADQLMNERPDLTQRLFAQMMALFRQGVLHPLPYSVFDANDIIDAFRYMQQARQI
GKIVITYRNGIRDIHPPAAPHRAGLTLPANATYLVTGGLGGFGLRTAHWLADKGARNLVL
ISRGGPTTDAAQAAIAALQAQGVCVHAVACDVTDRKALARLLDETATTLPPLKGVVHAAV
VIDDGLARSATPEQIERTLAAKVLGAQHLHDLTRAKPLDLFILYSSATTLFGNPGQSNYV
AANTWLERLAAQRRAEGLPATCIRWGAIDDVGFLARNPKIKDALQGRMGGGALASQVALD
ALEDMLVADVSGLGVLELDWRALSRFLPTAGLPKFSDIARRAGDAGDDDGGADDIAHMIA
TLDDATLHERFTDMLKTEIGEILRVSPDKIEATRSVYDMGLDSLMGVELVVALENRFGIR
LPVMALNESPTPAKLAQRLVLRLRDEHSDAPGDAVAASVQQVVASHAAEVSSGTVSDFVD
EIRMNGSLPMQRIIP
>C6CCJ8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Musicola paradisiaca (strain Ech703)|TrEMBL
MNQFENANLANSIAIVGMAGEFPGADSVEAFWQNLVAGTCSIEPISADEITPDPFKKIDP
TAKNFVPVAARLRSVEEFDADFFDFSAREAEVMDPQHRRFLMCAWRALEDAAIDTERFAG
AIGVVAGGTMSRYLMNCLSHQEIVDAIGFDAMGIGNNLDFLPTMLSYKLNLQGPSYSVQT
ACSTSLVAVHLACQMLLNHEAELALAGAVCVTVPQDSGYLYQEGGIVSPDGVCRTFDQAA
NGTVFGNGVGVVVLQRLEDAIAQKHNIHAVILGSAVNNDGHQKVGFTAPSVDGQSRAIVE
SLAVSGVTADTITLVEAHGTGTRMGDPIEVAALTNAFRNDCAAKQYCALSSVKPNVGHLD
AAAGMAGLIKTVMSLKHQVLPPSIHVDKVNPDLKIEDTPFYINRELAPWPSPEGPRRAGV
SSLGIGGTNAHIIVEEWCDSPRSALDQQANDVVLPLSAKTEPTLSALRKTLADYLSKHPE
ICAADVAFTFAVGRRFFEHRQALTLPANLCGEALAQRIMANEQPETSAGQKDIGVLWQQG
AVVDWQGYYQALDCRRVSVPGYPLAQNRYWLDYRFPENGATTLVTRQVETADWFWQHSWR
RQLITASQTAADALPWLIFVQEGEASEWLADGIEQRGQPLIRVYAGDTFSQQSAKRYVVA
VEEPASYLQLIEHLSVSEGVSHILHGWLFSSKPVSSQHALAQGFYSGLSLLKALAAKTTG
QQQVWWITDSVFQVLGHETPVPYSALINGLNRVVTQESGRLICRQLDLCSGDDIALAVPA
IINEVNRQSNETLIAFRAGQRWVFAAEPLPLAPVSASQTQAGVYIITGGLGQFGLATASY
FIERDPQARVILTSRADVGLYHGQRAAQGDIETTRLAALEALWRKGAQVDVVQTDAGDEH
QVNALLEQTIARYGKVTGLVHAAGLIGEQTHISFIESDREHCERIFRAKVQGTQILIDAL
KDIPIQFVMFVSSLSPLLGGLGLTAYAAANSFMDSCATRLNRESQDKHWVSVNWEGWIRQ
GGVSADYDELGKTFQQLSLSDTEIRLCFERILAHPALSNVVVSTGSLTERLQRWSTIAGM
AEITGTIDESLTLGTRRDDKATVILDMARQLLGNPALGPDDDLFKFGADSLTAIQLIARI
RDLFKVDLPMQTLFDRPTVTSLVCSISAKDEDDELADLVAELEAMDDEEVRKLSQQIKDG
KPSRWIEI
>A0A2X5BCA8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Serratia rubidaea|TrEMBL
MKPRVIASGWGQCSPLAADFPALIEAISAGRCATGTPWFDSDDDWQNLRLGSNPHTVHAP
RADAEPWQQLQPVIDEALAMAGLQASALQGPRVRAFLAGNGMRPNIADFAGYQDRNDGED
LLFFPAIKRLHADSYAQDALARRFVDTYRLDWPPTSVYSASNSSLTALHLAQAGIAAGRL
DVALVAGWLKIVLQDVVFMGGQGMLGNGQSQPFSNQDNSVLLADGAVALVIESEDHARRR
GVTPAVAIRSSVCRQSSGGRGGAFTADFRTIAQTIDSALLAAGLTPQDIACALPHANGTV
AGDKAEAMALQKVWGKGGIPVVSYKGQAGYVATCSGVLDFMLAADALLQRRLLAAAGRHP
VDAALPIHVHMDAPPLPLHTPHLLKSGIGLDGSVIAMVLSDCRESPHE
>A0A165UQV8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudovibrio sp. Ad26|TrEMBL
MLEIVGLSVRVPGASNKEALWHLLKSGQNSISEIPTDRWSHFRYLHPRTSEAGKAYTFKA
GVLDNLWDFDPTAFGISPREAEQMDPQQRILLQLTWEAIEDAGISPDEIAGDHVGVYVGA
SALDYANESLFDPNVATGHFMTGNTLSIISNRLSYIFDLKGPSFTVDTACSSSLVALHEA
YRALNSGRIDCAIVAGVNVLASPFPFVGFAQATMLSPDGQCKAFDANGNGYVRSEGGVAL
LIKRKDAPRWKGQRSHADIVAVDVNSDGRTVGMSLPSDVEQANLLDRVYKAHGIDPNRLA
FVEAHGTGTRVGDPAEAGSIGRTIAQKRRTPLPIGSVKTNVGHLEPASGLVGLAKSVLAL
QNDHFPASLHFNEPNPDIDFDALNIQVASEGVELPRGENPRYAGVNSFGFGGTNAHVILR
DPETMAENVEQLTQPKVASSLFLSAPTKEALVELASGYARDGVLTEQSKLKICAATFHRK
RIFPEKAVFSGTDVEALKTTLSDFASGQKNANVIYSNKTTSLGKCAFAFSGNGAQWAGMG
RDAYAANQTFKVAFEKVDELFTNLSGWSLKTELFSETLDDALKKTSIAQPLLFAVQVALC
QALEDYALKPDMVLGHSIGEVAAAHVAGALTLDAAVALVYHRSAEQEVVAGHGTMAALVL
PADEARQLISKSGFDSLEVAAENSPKSVSLSGTKEDIDGFAKFARANHVAFRKVALNYPF
HSQLIDPVEHPFRNAVGTVTATSAQVPFISTVSGAISDGKDLNADYWWRNLRKPVLFSKA
VATALDLGADTIIEIGPKPILQSYLRQVAAEKGGKGSVLSSLSNEQLGGTDPIINLVARA
FVAGINVDTDKLFGKNPDEPVNLLPLPWQNKSFRFENSGEANMGIFRGGDHPLLGWRPNA
NYNVWTTHLDRFTVPFLEDHVINGQMIFPGAGYVEMALAAGSALYGSDAVELRSMDILQA
LVLSDEYLTEVQTEISEETGTVKISSRMRLSGDDWTLHAVGRVAKLETPAPNIQLNFEAA
QLINTGEEIYTAALTYGLEFGPRFQRTQNVSQVDAGTFIVHLSALEDDEQVSSFGIHPAE
LDGCFHGLLSLFREITSQKSRPKAYVPIFFDKVRQYQTGASPAYVRIQVKRASELSILAD
FQIFDEDDNVIIAISGGRFRATELGRKDNPSDLIYRVEAELQRNPATTVAKLNHSFPAIE
DYVAEKFRTVEDEAEREAYLLLNAAAQRTAFDIISKFADGEQTVSVEDLPNNHRRYFVTL
LTILQEAGAATECGINRFELNSDFELPDFDLLVESVLEESPQDIAAATILATTRKFVLDS
LDLDSFEDNGFEHSSAMLEQYWYSSPEAQIRSQSISEWLRTALGTWDTDTPLHVLDLSGS
GLNLAKDIQQILPSQVTKVSIADSNHKSAARLSASVLDEPNIAVFDTSNLDSNHTWDAAL
EQGPFDIIVSSGLLHEACQSEANLFEKLGQSLTEGGQFLAMEPLSDVFHDVAFGLSEDWF
AGSISDEYPVGPLKTSNDWLDQFTSTSFNAPIAIEALKEGASIVLLNATAKPVDVSQQLD
PTADLPESKAMVILAGNSKLEQEIAQAIQNDERLSSCNIKVLDADSDQFDLNEANGWKSA
LAGSAFLDAELKTIIHLYGLAEAGDAPVDQVMKRCATCVGLVKAYPGLAGQLALVAPGGS
GHNAEQEAPAQSAAWTFARVLGNEAPELTPLALDVCIDKGAQGVASDILEAVFYQNMENE
LHQPQKSRVVSRVKSGFGQSTWKPAENVELNFSEAGSLNHLNWRGQQRIEPSEDHVEIKV
AATGLNFRDVMWTLGMLPEEALEDGYGGPNLGLEISGTVTRVGKNASDLAVGDKVVAFTS
GGYSSYVTCPKFAVAKLDQSQDLVSAATYPVAFLTAYYSLIHLGELKEDQWVLIHGGAGG
VGLAALQIAKHIGAKVIATAGSEEKREILRLLGADHILDSRSLQFPDKVMELTDGKGVHS
VLNSLAGEAMEASINIVRPFGRFLELGKRDYYANTKIGLRPFRRNVSYFGIDLDQILLHD
SDLARKLIEDVFELIKDGTFTPLPHRVFEGRNVQDAFRLMQRSGHIGKILITPPKPEEVK
VPQERTSLKFAQDGHHVVIGGLGGFGLEICRWLADNGARRITLTSRSAKVSEQHEKLFEA
LAEKGVTVSAVSCDVTDRTAVHGLLSELRQSAPLKSIIHAAMVLDDGIIQQLDEKRFRKV
LEPKIQGASLLDELTRQDKLDQFILFSSATTLIGNPGQSHYVAANGYLEGLARARRKAGK
PAIAVGWGAIGDVGFLARNAEVSDKLSRHLGEATIKAREGLDILKLAMEQDDGSAPGAVV
HIGRFAWAAAHQSLSLLSKPLFREIVGRSDTDGDSDGSTDILSLIEGKSDTEAKEIVAHI
LAGEIGRILRLPAEDISHQRPLAEFGMDSLMGLELRMGIQKRFNLEIPLVSISGGTCLDD
FAAQILQKLRKREGGEASVEEGSHSVLASQHLSDDLDDAQKSTVREILDTHQDKTARLLN
>A0A169PK47|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces laurentii|TrEMBL
MTSPGQTQTQASAETLKRAYLTMERLQRQVQEYERARSEPIAIVGTGCRFPGGVTDTDSY
WRMLAEGTDAVGEIPAGRWDHDAFYDEEAGAPGKIYTRAGAFLDDLEYFDHDFFGISQRE
AIAMDPAQRLSLTVCWEALEDAGLAPSSLAGSRTGVFMGAASWDYITAQLRHPDEVSAYT
SSGSAASFIPARIAYLLDLRGPNVAVDTACSSSLVAVHQACQSLRLGECDTALAGGVNVV
LSPLLMISQSQFGSVSRQGRARTFSDDADGYVRGRAAASSSSSGCPTHSATETGSSPSSG
AAP
>A0A448KD77|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinomyces slackii|TrEMBL
MKAMQIVSFDGAEGMRYQEAPLPEPSAGQVSIDAQYSGVGYIEALLAEGFLQRELPWTPG
LEVAGTIREVGPGVTGLEPGQVVAALIMGGGGYGQVVVTGADLVAPLPDGLDPALASVVP
ANTTTALIALEHVAHMRAGEHVLVHAAAGGLGSQMGQVARLLGAERVVGVTRSPAKRQAV
LDLGYDEAWLPEELDSAEGGQFDVVADPVSGPGRLRSLDLLRVGGRLLALGDAARGGDQL
INSTSLWLRGAGVIGFNLGALTAADPALVGQYLRRAVGLVASGEVGIHISERAPIQEAPR
VIAALRQGSTIGKTVLVHEPRS
>D5SX03|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Planctopirus limnophila (strain ATCC 43296 / DSM 3776 / IFAM 1008 / Mu 290)|TrEMBL
MVQVPPIAVIGVSCRMPGGDGIAEYWKLISSGSSAIRELPADRLDKSLYFDTEQGKPGRC
YTDLGGVVTERPVNRQICPISDKDLQTSDTAHLTLCEVASSALKHAGMDPAKVPYRRTGV
YVGHSGGSCLGGDAAFARYVGIAGEILRKQDEFKGCSPSARAEISRRMVDQLRSQFPDEE
SLKPMNFAAANAAMLISRVHGFEGPSLVIDAACASSLMALSQASYALARGEIDMAVAGGA
SYSKWFGLVLFSMAMSISATGSRPFDADADGLISSDGYGLVVLKTLPKALADGDRILSVI
RGIGVSSDGRGKSLWAPRQEGQILAVERAYSKNIDPASLQYIECHATSTQVGDATELKSL
AQVLTGKIPAGRKIPIGSVKANIGHALEAAGIAGFIKTVLAMEHGVIPPQINFKTPNPEI
EWKNVPFEVATNAREWDRPAGGMPRRAAVNSFGIGGLNVHMVLDDGLLPGEKSKTSVAVP
SAQPNSNVAPAPVQQPMAVIGMASILPGALTKAALWEALIAGKDPKCEFPKENSTLASTL
LAEEQKSQKPELTSRGGYVADFVYDWKRHKVPPKQVANANPLQFMLLDAADQALTDAGYE
KKPFDRNRSTVIVGTMFGGDFAVQLQLGLRLPHIQKVLREHLEANGTKPDQIDEALLQYE
KHFLKVLPALLDETGSFTSSTLASRLSKTFDFRGGAFALEAEEVSGLVAVNLGINMLETG
TTDLVLCAAGHQSMSYNSFEKLVEKDLLSKGQSRSAFDADFDGILPAEGVAVLVLKRLAD
AERDGDTIRAVIRGTGQCNRRNDEAGALRESFNTALKVANTSPKAIGAIEVSGVDCKDRN
FNQLELAKTIDQESGQPQALIGSLTPQIGYLRGASGVASIVKSILELQNGQIAPQFGLKK
LAAEVQPVAHAIPQKVMPLYATAPGEKGQIAISNSSLDGSGFSLILESAQKLPLRPVTTP
SVAISQPASAKQAPATLSSRQITSQSRRSKLALAFPGQGSYYAGMGADLIANYTEVRQKL
AEFNEVLKLENCPDFETLSADPGNSILNAQLSMLVIDLLYYTAYKTAGIQPDYVCGHSYG
EFPALVAAGALTFRSAVIATRDRSHVVEEFAGKQGTLLAVSSDASTLRHLLTRAPVEVFI
ANMNSPEQTVLGGTIDDLKQFEKILRERRIGSRLLKVPAAYHTPLLEPALVTYRDCIRAL
PISVPQIPVISGIGNREVTDPEEIRENLVMQLVSPMDFVGMVQLLRQLSVGMVVEVGPRK
VLTQLIQKTANEGQLECLPMDPRDNSSSDWQSTLRSKYEGSVGNASPAAATPQKTPASPV
PAQAQKPVSQPQKPAVQPAAANSSVSKPGQTKSCQINPTPATTNVPTTGSKVTDRPRIVH
FDATAKRKEENRLRAIQQRAESGRPVVTSASPKTTQNSPAISHSDLAETNGHSGHFEKNG
HASDVTSKAPALNSAQMKEEIVPPVVVIEEVPAAPRKLPNRAELEAFVVEYIVDQTGYPP
EMVELEADLEADLGIDSIKKAQMLGECAQKFELHWLANEVADLSLDQFPNLASIIKFLTE
DAAKATASPSEEQLAESVPAAALPAVAIVTETSEEVVPRKLPNRAELEAFVVEYIVDQTG
YPPEMVELEADLEADLGIDSIKKAQMLGECAQKFELHWLANEVADLSLDQFPNLASIIKF
LTEDAAKASSSANTIDAVAISKSVDTDAPREPAHQSAETLPAVPATTVTSETVTSEEVAP
RKLPNRAELEAFVVEYIVDQTGYPPEMVELEADLEADLGIDSIKKAQMLGECAQKFELHW
LANEVADLSLDQFPNLASIIKFLTEDAAKATASPAEEQPAEAVPAAALPAIAIVTETSEE
VVPRKLPNRAELEAFVVEYIVDQTGYPPEMVELEADLEADLGIDSIKKAQMLGECAQKFE
LHWLANEVADLSLDQFPNLASIIKFLTEDAAKASSTSRSASHVASPETELELQDSSTATA
TLTEPASVSTQAVTQVVEAVPAVSIVRESVMILQGSPYEMGFQHGQKEKAAIHGILERQI
TRYGARLDNMPELDEAVSDPARYFGEDEVAELKGIADGAELPLAFLIGHNLGLCEDYVPG
CAQFAVSAQANGGKGMIHAANEDSSLALSLTDCLRRVVQCRIPAHGYRHIVFSVSGQVSG
INGTNEKGLTVTSTLLLDRAPRDITAPGDIHPVLIKKILEKAATPAEAIEILKSSKRNGA
WGVCISHADTDSLCYVEYDSDQLEVRSGMTRVIGTNHSLLLGATHPTPPHSMHRMDRLQE
LLAKEEAMGLDFPAAEKTLRDQFDGGRQRVTAHATMNTICRVDNQISVVFGPSEKTIRVT
PGSYRKEFAHEFSTLDVDGFFGGADELVVNDVPTNSNTGSSVGSTSKLIPAQQTDLPRLA
GLPVIDERVMHRVILRPRLSPLSHAAQKVSLTGKTVVYGFGEVARALISKLKSTGLEVAV
IPTCFDVTKLEAEFENLAALKSARNLILVGPRSSDEVSEASASARFLTAFRLCQLWTQSG
QEICPLAERSLTFVSFMGGNFGLEGSPANADGGAMSGLAKALRRELAPLVVRTVDFASDD
VTDRVVDQLANELSQSFEICEVAYSRGERFVVAARPVPATPVPQNGPTPGSAWIISGGAR
GVTAVVARELGVRYGVHLHLIGSSPIPELDPSLLEASAEELKALRRKIMSEARERGEVPL
DAWSTFERSLEARRNLRDMRQAGVSVTYHCCDISQPDAVEKTVAAIRTFNHPIEGVIHGA
GVEHACRFERKQLPKVQKTFDVKVEGARHLAAALEHDPVAYFVGFGSTSGRFGGLGQADY
SAASDALAKFCNELGRKNPDWRTIVVHWPPWGEVGMAARPESKLALEAGGMAFMPPQEGV
AFLLEELASTSPEPEILIVDKPDGLDLDRTLPELAAWKDFAAAQQVVDASPLLDTVIALT
PGEYVEVEVRLNPAQDPFLYDHQHRNAPILPMTFGLETLAQAFRVLLPATEQVTVLDGEI
VNPMRFFADRQELAIARIRRSGDSFEGELVTRFFNRKGVLLKHERVLVKARLKPGVDAPD
AAKPFKSSMQLKKVQYAETWDQVAALNLGSVFTGPSIRGLTEFAYEGKTFEGIIVPPPIS
GFAGNRPATGWMLNPAVLDACLIGCDRWAAQAVERQSLPVNIEKVSLYRPAIDGDLCRID
GQVLEVTEKNLRFNFSLWNSKNEIILRVEGFCTTAVMGGSQPETSAEIPAGIASRAIPEL
KSLNPADLHLLFPVEAVTASADHWEAEVRIEPLTEPLMTAHRFNNSPLLPGAAMVELFAE
ALQQVLPGPGVARIRNFSIQHSLHLKAALPRRVQVVAHKEADGYRCQLIDLDGGSITLAT
ALIDRVDAANLQLPQLDQPKGSYSPMKYPDMGPLIHGAPLRSLQAMCSGRDDAWAEIVPT
DMSKLLGPNSKCQPVIHPAVLDGSFYACGIHAWINCFGRVELPLGFEELLILRDQPLSKT
DKLVTRVRYRDSDDKGSSYEISVFDKQKQPVYVVRNYRSVAKGSVTL
>A0A2T6IHR2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii TgCATBr9|TrEMBL
MTEAATPQNVTSPADLSKQNVSFRPGVNAVEFVSGYSHAGSVVCSLPSPIFFNKASSSNG
NCESNASTASSSAALGTEASSNVRTGTVLIFDCGSGNTWQHLRQWLSDEGASHIVVVHAC
AEEGADTLGVKTLHPSRVNGGQGCSQTLIKEVKCRPHHPEEVVELFKLLKEGLHFPLVRG
IFYILGEKLDSLLANQTTSSVHDMMKTASGAWSIHHALGQLGMEADLDFFIFFSSISALF
GSISQSISAAVHASLDALAYYRRHLGLAATSIQWAPWADGSSATSPQIVRHWLEKGGVSS
VRNPLAAVSAILKNHTAIGAVVACFHADPTIMHEMGETDQECTFLSSGPAANTRDSTSGN
VKVRTNPVKSRVFQNVSPSTDTCGENHKDELLVILTQLVRREVIEIASCYVFFEGNNLST
DESLVDLGLDSLSAVELRHTLQQRFCVNIEPTFLQANATIDSISALLVTHVATSLTGALP
VLPLSCPGLASAVDDCALVSLALRLPGRCDSLDAFWASLQSDSGYCRPGASEACDQCFMH
RAGSGELPAESQSIGTNLDARKGFCWLSNRDEFDSHFFGISFTEALATDPCHRLLLEATY
EALCKLNTEQQSGTSGTPIAVFATSSSTQMRASLPSYTKPASSQNTQDNNGCLAASFLSY
HLNLTGLAVPIDGSDSASLIALDLGREHLRGTDSVCQAVVVAAGSLLPICSHGWPSACTS
PTIRRFRGRDDHAFPDRETYAVPRGEGIVSVVLQRLSVARENGNSPMAILKGISLIRMGR
GERPIPSQWRTADVKLRRKTIVEALKMSRVEPRTVAVLETDGLTGSQAEDAYTVEAMADI
FGPRHLAESCSPLVIGNASLHIGQAREASGLATLAKLVLMLERGYAPPIPRLRRLHPDVK
RGILPSGFVMFPCKKMDLLAFRQHPDHVYGPNEKRDQKEGRPLIGCVSSLGSDKTSGCFI
VESSPRRHGRTSDTRVSLERAVPLAGTKDACSHNYLHVRSTDGSESEIRGDDRAVWLFCD
DLWGLQSVGRGLYCSDPAFAALLEQAERVLGNRIPQPLSCLLYPSTTAEFQKAEDALAFP
RIAAFVLFSLQWALATCLRHQEGEPTAVMGLGVGEIAAAAVAGILSLEDAVELLELLSSE
TRTCDYRNKPMPGGNVNSGGLFDRGNSGTGGCGVAQDCKSPWVLCGLNKTPTSESAALEF
SVLESRRGSSSRISSETPTSNTTPHNRDVFQERFSRKPRRATCPSPIIRHAWEKVAHGTP
ENDEEAELECPSSQSRRANCPSPAIQHACEETAHGNHANDGEADLLMDVFRFRPEPSEPL
GQVTARIALRNATCLFISTVSGRLATDTLIRAAEYWDPLVPKTQRVHRAVETAVQVAKTA
KLVCIGCSAQDGVHLSVGLPSVHPISPSPLRIFCFTGSSPSPQLLAPCESASGSSPRVAV
VEHHGADSNLGGGAPWWKHLLFRLPQLEGFPSGCSASTRLLADRLVADVPTPDNHMINNP
QTAAVQGAGETLGTLREGSSGEGEDGEKGYRSESVNTQHPVYKVYRRCSEPELHESELSL
LCSDTVCQPSLEKTVELFIGTGLEQQGKLSTVSSSWLVFSDIVAPSPISLYSTLAFQNED
GEQRFCTLNVASQVATVYAEKVKTQVCSIIIECKRGFKPPREIARCHFVKNQTAVGKHEP
AVSSLSRIRWLPATKLSEGWLRTRRPHVWPCKIKVTKAACPLPTRRVDLQEIYWGKRHIL
CRFRMPRNPPRDGVEKSTQLIAILARLVTVSVGVAATCVLHETETSGRYSHSHPGPQVED
DQKTHMDALWVCPYVPFSECWCVIRHRRNGSSIKEGKGRDWETCDVEIFSENGTAVAVVL
GFGIQSHALSMRMMEGRGNDGDSSVSTTVCVA
>A0A3E2N2X3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium marinum|TrEMBL
MMGAGLSNIDSGELDERQLADWLIGKVGLYLNMSPGSVDVDLPLPECGIDSAMSLSLCAD
LQREHGIEADATIVWDYPTIRAMAAHLMSGEF
>E3JCX2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia inefficax (strain DSM 45817 / CECT 9037 / EuI1c)|TrEMBL
MSDDQIRRLLRRVTVELDDAQERLRRLQDRDREPIAIIGIGCRFPGGVRDAESLWELVAA
GREVVGDFPRDRGWDVDALYHPDPDHPGTSYTNRGAFLPDVAGFDNGFFGITPREALATD
PQHRLLLETAWETFEHARVDPTALRGSPVGAFVGLSLNDYARLDHTPRELEAYLGLGNAP
SVASGRISYAYGFTGPAVTVNTACSSSLVALHLALRSLRSGESTLALAGGVTVMSSPEEF
IFFSRQRAMSPDGRCRSFAAAADGAGWSEGVGLLLLERLSDAQRNGHEVLALVRGSAVNS
DGASNGLTAPNGPAQERVIRAALADAGLTAADVDAVDGHGTGTPLGDPIEAQALLATYGQ
GRPAGAPLWLGSLKSNLGHAQAAAGVAGIIKLVGALRHGVLPKTLHVDAPTPHVDWDAGA
VRLLTESRPWPAGERPRRAATSSFGISGTNAHVIIEEAPAPLPPAEPAAAPSGLPPVAAV
GAVRPPWVLSARDPDALAVAAGRLAAHVRAHPELDPAAVAYTLDRGRAHLSHRAVVIPDP
PSPGREPGSEPGLAPYLPGLDGLAAGEQPANVVRGQATAPGRVVFVFPGQGAQWDGMTTD
LLETSPRYAHHLHQAADALAPYVDWSLFDVLYRRPGAPTLDRVDVVQPALWAVTTSLAEL
WKAHGIVPDAVLGHSQGEIAAATTAGILTLDDAARAIARRSQAIATIAGTGGMASIALPA
DAVQADLDADPGTGLSIAAVNGPTTTVVSGPASAITAIVERYTAQGLRARVIPVDYASHS
PAVETLRARILAELGGLTPRPGHTPLYSTVTAGIADPAALTADYWYRNLRQPVRLTDAVH
ALKADGHTTYVEISPHPVLGTALTDILENTATITATLRRGDATLTRLHTSLADAHTHGAA
VIWNPDPAPTPEPVDLPLYPFQHQNYWLAPTAQPPLPATADQADQFWNTLQTGDPDALAT
LLGATDPVTRTALGTALPALTAWRQTHTTRATIDRWRYRIAWQRVAAEPAPLTGDWLVTV
PDELADAPWVRALLDVLTGREASPVLVRVARDATDRVALAGLVKAGLTGPPRGVLSLLGL
AEGSHPDFPSVPWGLAGTVGLIQALHDGDIPAPIWAVTRGAVTTGANDPVTDPEAAMVWG
LGSSAAAENPAGWGGLIDLPGTIDQDSLQLLATALGQTDECDLAVRPGGLSVRRLVRAPM
TEPDATALTPFTPTGTSLVTGATGAIGQHLARWLAHHGAPHLLLLSQRGPDHPDADQLLK
DLTATGTQATLIAGDIADADHLTHALTHIPPNAPLTAIYHTAAILDDALTTDLTLTQINN
TTRVKVDGARNLHHHTDTHNLTHFVLFSSMAGISGITGQGNYAPGNAYLDALAHHRRHHH
QPATSIGWGHWAGGGIAAPHIEAQLARRGLTLLPPATALTALHHPLTHDTTHLVIGDLDW
DVLWRDKPDRLYRDLLRQPPAGPAAIEPAAPTAAPRQGLAGRLADLPEAEGRRTVLRLVR
AHVAAIGGFGGPDAVDVRVPFRDLGFDSVTAVELRNRLGNETGLRLATTLVFDHPSPAAL
AEHLFAELAPAAGPAVTVPAPAAAHSAASPGAPAGTGTAAVADELAAASDDELIDFIGKE
LGIS
>A0A086K161|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii GAB2-2007-GAL-DOM2|TrEMBL
MAGAVEPVSRLFERVEFSEPAIPFISTVLGRLAVGSELSDALYWSEQITKSVRFREAVVA
AFGGAVAGLSAVEVGPKRTLANIGAAYVNGATHPGCAWLCVIEGPATSESGSQFESFLKQ
VASLSSRKLHWNHRTFPLARLQEQKTEDAGQNLRSMAKPSPHSQPSIWSEKWAYHSSVPE
NDAAFKVPKKAWIIVGVPSQHMAEVLLSLKRMGLDTSRVCGLGAISSMETLQNLVQGGTW
AGMLVVSGLWATVSAVESLTETAHILRHYACLSTEIEVPVLAVVTRGAQRSVVSPETFGQ
RERPTLESVPQQNQVFGHLEDEVPVHAGLLAFCRTLRLEMGRCCRRFKPFLYFDTDRLHP
RQSKESLDYHLGAVLKWLSRNDVPASFSEQIRPDSDTLREWDIVIRKQSYFVPRVAPVLL
KQPSTTAAGRIQKAKSYIVTGGLGGIGIVVASWLLRQGAGRIFLWSRRGVPTDDVKETNQ
WCELNAAMETGRIQTVSCDVSEIEQVRHSIVLAVTDSILGGIFHCAGTEGKGKLQDVSQQ
DIADVYASKVEGAWNLHRICSEMSINTNLDFFVLFSSIAALPGNDAFATYAAANGCLDSL
AEHRRSLSLPARSIQWGPWLDAGMAARTPSFERFMRSRGIRGFHNEEAISHLETLLTADE
SLTCCAAVHVDWRIYAHIFGSHVPTWLQDVVPGLQTSLTPFSESNAPEQMHGSMDIQGVE
SAVIDVARRLCGAEGIVSASTEISSLGLDSLGAVEFRNALQEALKIKLPASLLVEYACLK
DIIQFIMENCFSDAARSTSDLVPLVTREPAANDQGFAVVGMGCRIPKNATTTEEFWDMLL
HEIDAVCEIPMDRFNIDAFYDPDPEQDKCYTREAALLDHPDFFDNTFFNLSDQEVLAIDP
QQRVLLEVAYEALFEAGFTKEALLGKDFGVFCAAYNNDFQFTNLTQGKATMCVFDKGEGR
GRIPSLGEAAGYPEPGGFMCFIPNRISYSFGLTGPSIGIDAACASSLVAFDAAVTKLKRG
ACSGALVGGVNIILSPTFFLGGCKAHQFSRAGRCKTFDCNADGLVRGEGCGAAFLLPLDA
ARETGAFVHAVVRGSATCHYGRSSQITSPNTRALTRVLRLSLQDASTAPSLVRYYEAHGT
ATVLGDVIEMSAVKDVFQTGRNAAAPLHMGTVHNNIGHLDAAAGIVAFLKTVLCLKHRFV
PANIHFKSLHPDIHGIDTQLIKYTRESHSIMTDDVATGVRKTIFGANLAYGMGGSVAAII
TESGDEEADRRSLKAAPRHVWNHRRFPLNTQKFVYLMGAMGQISMDDMPTPQSDVIHVMK
RLSATALNVAFMRKLSPSTCAAGSIRSVFLTGATGFIGSQVLFHLLQVKRQDPKLGTEDK
KLTIYCLVRARDRAHGIYRIRDSLVGRGIEWKHEFDQQVIPVIGNLEEGENMGLGPKQMQ
YLEQTVDAVYHAADYVNFAAPYDALRKSNVLSLIPILKLCTTYVAKPLHLVSNFAHHLQY
FAGFSEDLNIAVDETVSPPLSPASIDRLEQQMPAGIIGYPWTKWAVEEIIGRMKDVLHER
CEEEGQRVSMEESEKNDILSKFQVTVYRLPNSCVYYNNGYTNFANASLSLVLASAQERMI
PPGVLPVGAPFLTTPVDLITGILVKLSMTERKRHHVYHLVSLRVARRKHVVQAIKWLFPD
SVECTADELFRRIDENKENSPAHPLRAAMRFWRRYWYSSDTDRDSPFPVAVNNVEDDLPG
VMATFPSLADTWLRMASYCVKNYHMVRHPFTLAISFERLKKAIAGITKQRIDELALPSQT
QELLNETCSTEDTTDIAAVKALVEHANLRKYDDCAVSDVPDPRARA
>A0A031HMT8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Delftia sp. RIT313|TrEMBL
MRAQDAGYSGVEIAIIGMGGRFPGADSVDALWRNIREGRESVTAFSDEALRHQGTEQALL
DDAACVKSGVVLEGLDWFDAGFFGYTPREAGQIDPQQRVFLECAWQALEHAGYDAERLDV
AAGVFAGAGANLYLMRHLLGRARWSGGIAELIALLNGNAADALCTRVAYKLNLRGPAVTV
QTACSTSLVAVHMACQSLLGMECDMALAGGVWLNLLQGAGYLHQPGAILSSDGHCRAFDA
RADGTMLGSGAGVVVLKRLDEALRDGDTVHAVIRGSAVNNDGARKIGYNAPSVDGQAEAI
RAAQAMAGVDPASVGYVEAHGTGTTLGDPIEIAALTQAFGGAGGLTGRAPGHCALGSVKT
NVGHLDAAAGVTGLIKAVMALRHRTLPPSLNFSTPNPRVDFAASPFRVQTAAQDWPAGPL
PRRAGVSSFGMGGTNAHMVLEEAPASLPADASEKSGQAPQLLLLSARTPQALQASASQLA
RHLEQHPDLALADVAHTLRVGRKRHAHRLAVLAHGVTQAIEALDHPAPLVHFTGSVLSPQ
PGLAFLFPGQGAQHAGMARSLHAQEPVFRDIVDRCCERVRTQTGMDLRPWLLAQADDAQA
AQALARTEATQPALFIVEYAMARLWMSWGLQPEAMLGHSIGEYVAACIAGVFSLDDALDL
VVARGRIMQATEPGAMLAVGLPEAALQDWLCRGCDLAAVNAADLCVLSGRPDAIAAAEQA
LAGTGVLLRRLQVSHAFHSALLDPVLDAFAHQLASVRFNRPAMAFISNLSGRWIRDEEAQ
DPRYWLQHLRGTVRFAQGLDTLLDQSDRILLEVGPGQGLSGLARRHPKAGARTVLASQAA
ANREELQADQPARCLAQLWAAGVGAAKAPLLNSAQGARRVPLPGYPFERESHWVAATVPA
SEAAPAAPGGLHGTDPRGWLYAPVWQRSAPVVRAAAVPAGGCMLLLAEAGSTLAESLAQA
WSDTQPAPVVRIEPGPLHERLGPARHALRTTERSDWTRALGQIAAEIGPVACICDLWSLG
TLDDAQAAERCLLGPLALAQALEAVPAASAVGAAGRQQMLLVTDGLEDVTGTESLQPAKA
MLHGPCLVIPQELPGMACRIVDVLPVQSGHAQGMAALAQRILAEFSEPAPACVALRGPHR
WTRRYERIAGQTAPAVTPAAPATAPRLRRGGCYLITGGLGGMGLALARHLAEHWQARLVL
LGRSALPERGQWQALAQDAQTEPALRVRLQQLLELERLGAQLCLVQADVGSEAQLRTALE
QAQRAFGGMHGGIHGVIHAAGLAGDGMLADKRAHEVMQVLAPKLQGTRALLAALAGQPLD
FMLLCSSLAAVAGGLGRIDYAAANACLDALAVAHGRTAGWPLISVGWDGWRGVGMAAGTS
MPEGVGIAPEQGVHLFERILAGPLQPLVCVSTTDLETRRHADLAELLDQALPAAATTAAT
AGPAPTQVRPGGMAGFVAPEGDLETGLAALWSGFLGVAPVGAEDNLFELGGDSLMAIQLL
ARVRQAYGVEIHPAALLRTPTVRRLAELVETRLIEEIQALDAEAESAPTTASPIYS
>K9QFB1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc sp. PCC 7107|TrEMBL
MSNQEMDDSIKGIAVIALVGRFPGAKNVDEFWQNLSKGKESISFFSDAELKAAGVDPAWL
SNPQYVKAGAILSDIQMFDAAFFDFSPREAELIDPQHRILLECAWEALEQAGYEPGASKS
LTGVYVGTNMSNYFMSNLSSHPDLSKLTDVIAFGNSQDFAATRVSYKLNLKGPSINIQTS
CSTSLVAVHSACQGLLNYECDLALAGGISIESLQKQGYFYQEGDITSPDGHCRAFDAQAK
GTIFGDGIGLVVLKRLEDALEEGDYIHAIIKGSAINNDGAAKVGYTAPSVVGQAEVIAEA
QAIAGVTPETITYIEAHGTGTILGDPIEISALTKAFTARTQKKGYCAIGSVKTNIGHLNT
AAGVTGLIKTVLALKNQKIPPSLHFQQPNPEIDFANSPFYVNSQLAEWETNGTPRRAGVS
SFGIGGTNAHIILEQAPDIQPSSPSRPWQILLLSAKTSTALETATINLATHLQQHPEINL
ADVAHTLQVGRRAFEHRRMVVCRNTEDAVKALTSAEPQRVLTHHRQPTHCPVIFMFSGQG
AQYVDMAKELYEQETIFQQQVDNCAAILQPYLGIDIRSLLYPSSQETETASPQLQQTAFT
QSALFVIEYALAQLFMSWGIQPQAMIGHSIGEYVAATIAGVFSLEDALMIVAKRGQLMQQ
LAPGSMLAIPLAESDVKLLLNADLEIAVINSPSACVVSGTKVAIAALQSQLSSQGIECRL
LHTSHAFHSQMMQPIVGEFVEFVQQFSLHPPSISLISNVSGGWMEDAQATSPSYWGEHLR
RGVRFSDGISLLIQQFEGVFLEVGPGRSLSGLTTQHLHRDAKQLVLGSLRHVKDQLSDVE
FLLQTLGRLWLFGVEVDWSAFAVDEQRHRLPLPSYPFERLKYWIDAKSASPELKNHSAKL
DSKQEIADWFYIPSWKRSLLAKISSDDQEDWLFFVDDLGIGEQLAKVLINQGKNVINVKR
GEQFKQIDNSNYIINLYIKEDYDLLLKEIISSGGNIQNIVYVWSLDYLNESKYLEFNSLL
FLTQSIGKLKISDLQLWVISNNIQQVNGYEQLEPEKATILGLCKVISQEYSHITCRCVDI
DLTNRQGAESAEGRNGYYESIAQLANELTSVSSDLVVAYRNSYRWVQTFEPIRVEAILEE
KTPLRQQGVYLFPGGLGDIEVAIAQYLATNFQAKIIFIEDENFPEKDDFSQWLENHSQQD
EVSRKIERLLVLEQLDPTVLVIRIDATNFSWEKIGEINGVIYKTGIKREDLFCSISEIQD
RESTDLFNFQHHHIRLLTQVLQNQNLDFCVVFSSVSPILGGCGLSLDAAASYFLDTFINQ
HNCKNSLPWYIINWDKFNQAQQTSELAISAKEAVEVFQRIFTLEPGTQVVISPVDINTRN
NQIFNPHFFTNSKSFNELDSSSRYSRPNLSNAYVAPTNNLEQQITEIWQEVLGITEIGIY
DNFYELGGDSLIATQLVSRLRAKFPVELPLRDLLLQAMIPAKQAEMIEELMLAKIAELSE
EEVAVLLNN
>A0A655JEB2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MHRSIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSVNGYTLFERTLA
DAPAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAMLR
KQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNFA
AKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRHC
VAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAAD
AARLQMLLDSRQFERYEGPTDPNLTIVDAVRTQLAAVLGIPQAGEVNLQESLFDLGVDSM
LALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERSHTAQKVDISRD
>A0A157QUI7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Bordetella trematum|TrEMBL
MAKRVAIIGLAFRFPGTSTEQYWPDLLDGKNLITQVDSGRWSADAYLHPAKDQPGTAYTQ
AAGTLGDISGFDADFFGISPREAELMDPQQRLLLEMSWEAMEDAGVKPSSLRGSNCGVYI
GISSADYAYRIAEDLSAIDSSTATGNTSSIAANRLSYFFDLRGPSIAMDTACSSSLVAFH
QACRAIQGGECSHALTGGISLHLHPYGFITFSKASMLSRQGMCNVFDEAGDGYVRSEGGG
IFLLKDLDLALADGDRILAVVAGSAVNTDGRKSGLTVPSAEAQAELMRGVYAQAGISPAD
LDYLEAHGTGTPVGDPIETRAIGAALGKRRANTRPLPIGSIKSNMGHLEPASGVAGMVKA
IYALRHRMVPATIGIRKINPNIALQDWNIEVVTQNLALKPQGKLTIGVNSFGFGGANAHI
ILESAPPAAETSTTKLVKNAPVPLVVTGKSQAALRAAAASLAQRLRAQTDRSLYDIAYQS
ARRRDWHAERALVFASDPLRAADDLQALAEGDAPKYRVATGTGLPQARGPVFVYSGNGSQ
WAGMGQRLMADPVFATAVHEVDALFADYSDFSPAAELSAASTTDRYDYAEIAQPTLFAVQ
VGITRMLAQRGVVPMATMGHSVGEIAAVWACGALSLPEAVKVIYHRSRLQGLTKGRGRMT
AVGISGAETEALIAELKLGHGLALAGANSHRGATVAGDPAQLDALEAVLEERGVFYRRLN
LDYAFHSPAMDSIESGIMQSLADLKPRDADLPFYSTVSGGKQDGRALNAAYWWRNVRLPV
QFEDASAAAIHDGFNVFVEIGPHPVLRAYLKDALGQADREGRVLITASRGGDDPEKIHDI
AGQLILSGAHVNWETLFPWQGDYAALPSYPWQRERHWHPITPQSPGLLMRQRVHPLLGYA
HGQQDGLWENTLDTQQHPLLADHVVGDAVVFPGTGFAEIALAAATQWQPGEYADIEELEI
RAPLLLAPSPSKCLRIELEKRDGRLWIQARELGSETPWTLHAGGRIRQEADGALLATGDA
LLLPARAPDFDAAEHQRLTTSVGLDYGPAFRAVAHGWNEAPDSVLAVLQPDDSLTDELPR
THLHPALLDCTFQLIIQLLKDDPAMGRGIAFVPAKIGRLCLHTGQGQPKYARARLRRRTP
HSLTADFDLFDAAGKRIACVREARFRSIRLRKTGSEHLDFVDAILTPCPHPDAAPRANLL
PAERLMRTLQQVARAEGPTDDDRYTQEVDPLLESLCDRLALEALRAVSSSGQALSAAQVE
RRLRQHPEAATLFNLTINRALAAGLATASPTGWTLLQEDSDDAASAEDIWNSLLREYPDY
FPAIFAAGRIGLHLAELLQGSADIEQVAPKAVTPTVISRLVLGAERGQALASALAQALQQ
AAAQRQPGQRLGLLEIGQGAPLFGPACCATLDLRIADYCYASLDSQAVEDARHAQLDRFP
DASAALIGEPAEGPAKRYDLVILHHEFDSPQAGREALDYAVAHLKPGGTLLIRGTHPSAW
MNFIFGARASWWQQDHEQLLSALPQQTDWQALLQPMGLNCEPLLEFAPGSQSGAYLLLAS
STAQAMAAPACEPRQLLLLTGAADAPDTRLAQALQAGLQQAGQSCQIAPAAPAAHLDALI
NDMRVQHGPVHDIVLLAGWGQDGDDDAQRLQQQVQRCALAAALIQACERTDTPATVWLLT
RNAGVTMGGGDPASQLLADAALWGYGRTLANEASNYRIRLVDLADSEAATRALLLDLLRP
DAEDEVLIDAAGERLAPRLYVVPRPAPQRPDEESQAYRLGFDFPGQLRNLRWEAYDAPQP
ADDQIEVRIHATGLNFRDVMYALGLLSDEAIEDGFAGPTLGLEFSGVVTRVGSAVQDYRP
GDSVVGFGPASFGDRVLTRASAISAIPDGISFEAAATIPSTFFTVYYALHHLARLEEGEK
ILIHGAAGGVGIAAIQFAQWRGAEIYATAGSEEKRDFLRMMGVQHVYDSRSLVYGDAILA
DTDGQGVDVVLNSLAGEAINRNLQVLRPFGRFLELGKRDFYENTRIGLRPFRNNISYFGI
DADQLMCERPDLTRRLFGEMMELFSEGVLHPLPYTVFDANEVVDAFRYMQQARQIGKIVI
TYRDGIQQVQQRQPQAAPQLQLPADASYLVTGGLGGFGLRTAQWLAEKGARHLVLISRSG
PSTDSAREAITALTAAGVQVHAAACDVTDRQALAQLLAKLPAGMPPLRGIVHAAVVIDDG
LARSTSAAQVERTMAAKVLGAYHLHALTQDLPLDFCIYYSSATTLFGNPGQSNYVAANHW
LEALAAHRRALGLPATCVRWGAIDDVGFLARNEKIKDALQSRMGGAALESAVALQALERM
LLADASGLGVLELDWNALSRFLPSAGAPKFGALARRSGEHASDEDHGNDIAHLLATLDDD
ALHAAFGDILKTEIGEILRVSADKIDADRSIYDMGLDSLMGVELIVALENRFGIRLPVMA
LSESPTVNKLASRLIPLLRGENTPEGADPMAATVEKLVADHAADVSPTAITEFVEELKNG
EGGAAQRMIP
>A0A2P8AND0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MH33|TrEMBL
MVGRAVLERRAVIAAADRDELLAGLRALATGSPAGTVLTGTGSTPGRLAVLFSGQGAQRA
GMGRELYDRFPVFASAVDEVCAQLDPLLPQPLTTVLFAEAGTPAAALLDETVFTQAGLFA
VEVALFRLVESFGVVPDFVGGHSIGEITAAHVAGVLSLADACALVAARGRLMQALPAGGG
MLAVAADEAAVAESIADRADRLGIAAVNGPHAVVVSGDVAALDEVAEFWRDRGARTRRLT
VSHAFHSPLMEPMLAEFRAVLEGLSFSAPLLPVVSNLTGTLADADDIRTADYWVRHVREA
VRYADGITALRDAGVDTFLELGPAAVLTPMNAGLLPDDGAAVATLRAGVPEVTALLTAVA
TCYAHGRDVDWPAVLTPLAGPRPAPRDLPELPTYAFQPQRYWPTLAAPVGGAAEPADSEF
WRAVTDGDLERLGIDTRQPLRDLLPELESWRRRRRQDGILSGWRYRVTWRQRQLTGGDPG
RWLLVAPPRESTDTIADALRAGGAAVRVLTLDPATVDRDGLAAALDRAGAEHQPTALLSL
FAFDEAPHPEQDALPSGLAANLLLLQAHAGRDAGAPLWLATTGAVATDEEPATRPWQAAS
WGLGLAAALEHPRHVGGLVDLPGTVTAEACAALVTALTNREGEDQVAVRASGTHVRRLVR
ATGPAGGTGGGWTPQGSVLLTGGAGAVARHATAWLDRHGAAVVPLDQPAGGKLADRMAQL
ATDGRPVTGLVHVPADTATVPLAELTLPGLAADLLATVGDLPRYADEVENGILGALVICS
STSGVWGSGGRAGQAAGDALLGVLAANWRRAGLPVTAVAFGPWADGLADTDREQLSRRGL
PGMDPELAVAALRRAVADGEQVVVADVRWDRFVPAVAAVRARPLFGEVPEARDALRSLHT
DQPADDATAAALRERLRPLGDADQEALLVDLVATQAAAVLGHPGTGDLGPARAFREVGFD
SMTAVELRNRLRAATGATLPASVVFDYPTPLALARHLRTLVVQDGPGATAGLLSELEKVD
GLFAAGAPDPLTRQKLLVQMQAFLARWGDDRSAPAEAPVAPTLDGATDAELFEFIHRELG
GPGGNVPEDF
>A0A2P8AMQ9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MH33|TrEMBL
MAWSLATTRSTFDRRAVVVGADLPELLAGLDALAAGEPAGNVVTGTASGAGTGPVFVFPG
QGAQSAGMAAGLVGRCPVFDERLAECRQALAPYLDVDPVAVLTGTDESWLDRVEVVQPVL
WAVGVALAAVWRAAGVVPDAVIGHSQGEIAAACVAGILSLDDAARTVALRSRALAALRGT
GTMASVDLSADAVTERLDGFPGVGVAAVNGPATVVVSGPPQAVADLVDACQADGIRARLI
PVDYASHSAAVREVAEQLRTDLANVTPQPGHTRLVSTLTGEWVDPAAMTADYWYDNLRRT
VRFDAAVRTAITAGHTTFVEISPHPVLTMPVTAILDDTGTTGHTLGTLRRGEDDPTRLLT
NLATAHTIGLPVDLTAVLAETDPVDLPTYAFAHQRYWLDGSGGPDPDLLQGGADPNDAGF
WAAVERGDLAALADVVATEDTPAGQALDALRPALPLLTSWRRQRRRQSDIDSWRYQDTWK
PLTGIANRGMAGTWLVVLPTGDIIEPWQDACVEAFAAAGADVVPVPVSTTDADRDLLGKL
LREALAAGGGEGDEPAEVTGVVSLLAFDELIHPLHPSVPGGFAATVALFQALGDVGLSAP
MWSVTSGAVSVGRADLLRSPTQAMVWGFGRVAALEQPQRWGGLVDLPEAVDDRCAGLLVA
ALTAAGEEDQIAVRPGGLLGRRLTRVPLGDSRPTHPWEPSGTALVTGGTGALGGHAARWL
ARSGVPNIILVSRRGMAAPGARQLVDDLTALGARAEVVACDAADRDALAALIDGIPAEHP
LTTVVHASAVLDDAMINDIRIDQIERVLAAKVDVAWHLHELTLDLDISAFIMFSSFAGSV
ASSSVGNYAPSNAFLDALAQHRRGLGLTGTSIAWGAWAGGGMADGPLGELLHRHGVPEMA
PEAAIAALHQAVDHGEAFLTVADIAWERFSVAFTATRPGPLISDLPDVRRLRAAERATGA
DLPDGPESLREGLAGLPAADRLAVLLDLVRGQVAAVLNYAAGESVDEHRAFRELGFDSVT
AVELRNRLGSATGVALPVTLVFDYPTPTTLAEYLYAEVAQDDVVTPAALLDDLDRIADGL
DVVARDEAARVRATVRLQAMLSRLGQGGGDGLGRHLDDATDDELFAMVDRDLGLS
>A0A3G8JMG5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Gordonia insulae|TrEMBL
MSDHAGTITDAAAATSGPRLPDGRVPILISSDTAELVVEEAAAIRDWVRAHPDVDPARVG
AHLLRTRPARRHRALVIAVDHSRLVDALDALAAGRVHPDVVRGAGAAAPRRIAYTYPGQG
SQRPGMGTSYYRLSEHYRREVDTCHEQSMRLFGSSPRDYVLGELDADDPSATDVRTIQPA
LFMQMAGLTAMWDAAGATPALTVGHSQGEIAAAYRSGAMTLSDALTIVTIRARLVHELSP
RGHTMAVVGIDVDECEDMLARNSGWAQLSVVNSAHILCISGKREAVLGMVDTLSAQGKFA
KEIRVEYPAHTSIVSEYQPAFLDALGTYLENESMLAGTMPCIGATLGGAVDETMSLGDYW
FWNLRNRVRFDKAMTDAAVGHRADFFIEMSEHPTLLLAMGETLSDVDEAGLAARPVIGTS
RRDAVGLEEFTRNVAAVAVTDSGFRWEALQPADTAISTPNRRWAGSRTPSCVGSTCGPIV
RRVATTRSTARAGPRGRPAMRCIGWSRRGDCASAGVCCRRDGSRSSTRPDSVPTSRVRSR
PPHSSRGPRQSSSARAVSPWRPTPRFCWWGLRGRNPMVRWIIWPTSWSTVGGVADSIRCP
SSSGG
>Q08MN4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Stigmatella aurantiaca (strain DW4/3-1)|TrEMBL
MRQAGSPSSPEALQSLVISLVAARTALPVRSIDVREPLSRHGLDSAGAMGLLAELSADLG
RTLPATLLWEYPTIEALCGHLSGVEPAPAPRPGSVEDVLPGHEPIAIIGLACRFPGAPDA
EAFWRLLREGEDAITEVPSERWDTGAFYDADPAVPGKMNTRWGGFIEGVDQ
>A0A2K8RJC3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MTDDKKLLDYLRRATAELGQTKAALREARQAQHEPIAIVGMDCRYPGGVESPEDLWRLVA
EGTDAITEWPVNRGWDLEGRYDPDPERSGTSYTRNGGFLDEAGLFDAGFFGISPREALSM
DPQQRLLLETAWTAVERAGLDPHALRGTRTGVYIGAIGNGYGDGSKDVPELQGLLDTGTA
DSVVSGRVSYVLGLEGPAVSVNTACSSSLVAIHLAVQALRTGEATMALAGGVTVMATLDA
YIAFSRQRGLSSDGRCKAFADAADGTGWSEGVGVLVLERLSDAQRNGHQVLAVIRGSAIN
QDGASNGLSAPNGPSQQRVIKEALANAQLSAGDIDAVEAHGTGTKLGDPIEAQALLATYG
RHRERPLWLGSLKSNIGHSSAAAGVGGVIKMVMAMRDGTLPKTLHVDNPSRAVDWSAGNV
RLLTEAREWNDEGGPRRAGVSAFGVSGTNVHTILEQAPVEELVSGEAVGAPVASAVVPWV
VSGRSVEAVRAGAAGLVSLVDEDRAAVGAALVGRSVFEHRAVVVGESAEEFAAGLKAVAD
GEPLAGVVSGAVSATGKAVFVFPGQGSQWAGMAVELLESSPVFAARFAECERALSPLVDW
SLTDVVWAGDFGRVDVVQPVLWAVMVSLAGLWESVGVRPDAVVGHSQGEIAAAVVAGALS
LEDGARVVALRSKAITGLAGRGGMVSVPLPVDEVRSLLPEGVSVAAVNGPSSVVVAGDPA
GLETVLASVERAKRVPVDYSSHSVQVEEIREEILRVLAGVSPGEATVPFFSTVDVEWADG
TGLDAEYWYRNLRRTVEFEAAVRGLVDAGHSAFVEVSAHPVLTMGITATVGDEVVVSGTL
RRDEGGLRRFLLSAGELFVRGVGVDFTSFFGGTSAYRDLPTYPFQHKWYWLEDSVGMAEA
EQNRFWQTVEDGGLSELLGVDPQTPLSEVLPVLSDWRNRHDSRATVESWRYRVTWKALPG
GGSGELSGHFLVLVPETGHPLVDEVCRTLEGAGATVTRRELTAADGDRRTLARRLADVPR
PLDRVVSLVGLDERPHPDHSVVPVGTALTLALVQALEDAGVDAPLWCLTGGAVSTGDDDP
VTGVAQNLVWGLGRVAALEYPRRWGGLLDLVTGFDPAALVTALAGDGDEDQLALRPGAAY
GRRLERAPLPDGPAPEPWRPRGTVLITGGTGAVGGQIAAWLARNGAEHLVLLSRQGGEAP
GAAELTAELESLGARVTTAACDVTDREQLAALVADLEARGEHIRSVMHTAGAGSLVPLPD
TDLAEFGDTLHAKVLGAAHLDELIGEVDAFVLFSSISAVWGSADHGAYAAANAYLDGLAE
NRRARGLGATSVVWGIWAPQDGKGMAANLAEQQLRGRGIPFMRPALAIEGFQQVLDRDET
VVVVAAVDWDRFAPVFTSARPSALLADLPDARAALAGQDADAAAQDETSSPLLDRLRALP
AAEQRELLAELVRTQAAAVLGHESASEIEPGRAFRELGFDSLTAVDLRGRLNAATGLRLP
VTVVFDYSSATALADHLRDELLGTAVASAAPVAVTAPAADDPIVIVAASCRYPGGVRSPE
DLWQLLAEGRDAISELPGDRGWDLGEVYDTDPDRPGTTYSRAGGFVYDAGLFDPEFFGIS
PREALAMDPQQRLLLETSWEALERGGIDPTSLRGTHTGVFVGAGYQGYGGDGERVPEEAE
GHLIAGISSSVLSGRISYSLGLEGPALTIDTACSSSLVAVHLAAQALRSGECSLALAAGA
TILGSPLSFTGFSRQRGLAADGRCKPFGAEADGFGIAEGVGMLVLERLSDARRNGHPVLA
TVRGSAVNQDGASNGLTAPNGLSQQRVIQQALANAGLEPADVRVVEAHGTGTKLGDPIEA
QALLATYGQDRAAPLRLGSLKSNIGHTQAASGVAGIIKMLQAMEHGVLPRTLHADVPSPF
IDWSAGNVELLTEARPWEGPRRAGVSSFGMSGTNAHVIIEQVGPVEEPPVEEPALEDDAT
TAAPAVAWTLSGRTEEAVREQAGALLDRLDADPLDVGYSLAATRTAFERRAVVVGADREH
LAAGLRAVRDGEAPVHTADAGRRTVFVFPGQGTQWTGMALELLESAPVFAERFAECERAL
APYVDWSLTEVLRSGEYEQVDRVQPVLFSVMVSLAALWRSCGVEPDAVVGHSQGEIAAAC
VAGALSLEDAAMIVALRSKALIALAGQGAMMFVAMAAEPLRERIAAWDGRIGVAAVNGPA
AVTVSGDPEALEELGAALSGDGVMRWPIPGADFAAHSRQVERIHDELMRLLGGVTPRPTT
VGFWSSADSAWLDGSALDAAYWYRNLRQTVEFDQAVNQLIAAGYDAFVEVSPSPVLAIWV
QRALEAADGGVVVGTLHREAGGLDRFLTSLGELHARGAAVDWRAVHRGGRRVDLPTYAFQ
RQHYWLVPLPLEPRALPAAEDTDAWQYRVDWRVLHDLPTRPATGDWLVVTPAGTDVGGHL
DALRRQGLTTLVVPWEAADDRTTGAARLRAASDGHTPAGVLSLLGLADRPWSDGTVLPTG
LPLTVTLIGALGDAGIDAPLWAATSGAVSVSPADPLAGPAQAALWGLGGVAGVEYPGRWA
GLVDLPAAFDDRAAQRLLTVLTGESGEDQVAVRPSGVYGRRIAHAGRSGSAAGRPWQPSG
TVLVTGGLGALGGHVARWLATAGAEHLLLTGRRGADTPGADELTAELRALGARVTVAACD
VADRDAVAELLAGIPAETPLTAVVHAAGVLDDGVVDSITAERAVGVARPKADAALVLHEL
TREMDLSAFVLFSSLASTVAGTGQGSYAAANAYLDALALHRRDLGLPATSVSWGLWAGKS
LTDEAVAARLVRDGMPAMDPERAVAALRHAVGSGEPHVIVSDFAWDRFVAAFTALRPSPL
IADLPEVAALTERTAVPERPAALDRAALLELVRTAAAEALGYEGADAIGRDRIFKDLGCD
SLTAVELRNKLSAATGLRLPVTLVFDHPTPTAVVDHLAAELGEPEVRTETAVVTAAGAAV
TDDAIAIVALACRFPGGVRTPEDFWRLISEGGDAITPFPTDRGWDLDALYDPDPDHHGTT
YARGGGFLHDLADFDPAFFGISPREATTIDPQQRLLLETTWEAFERAGIDPQSVKGSRAG
VFVGSSYHDYGLRVRNAPQEVEGYLGIGSAGSVASGRISYTFGLEGPAVSVDTACSSSLV
AIHLAAQALRSGECTMALAGGAAAMATPTSFVEFSRQRGLAEDGRCKPFAAAADGTAWAE
GVGLVLLERLSDARRNGHPVLATVRGSAVNQDGASNGLTAPNGPSQQRVIRDALAGARLA
PADLDVVEAHGTGTRLGDPIEAQALLATYGQDRAQPLLLGSVKSNIGHSQAAAGIAGVIK
MVLAMRHGTVPGTLHVDEPSPFIDWSAGSVDLVTENTPWPVTGHPRRAGVSSFGVSGTNA
HVILEQVPDGESAAGAGVREPLSVPLVLSARSAQALREQADLLDRHLAENPDVRLADVGY
TLATARAHLEHRAVVPYGDRDTVRAALRSVTGTVPPAEPRMAFLFSGQGSQRLGMGLGLH
REFPVFAEAFDAVCAALDPLLERPLHEVIGAAAGSPDGELLDRTAYTQPALFAVEVALFR
LAEHWGLRPDHLIGHSVGELAAAHVAGVLSLPDAALLVAERARLMQAMPAGGAMVSVMAP
EETVLPYLAEYGDRVTVAAVNSTVATVVAGDEDAVLDIAERLAADGRKTKRLRVSHAFHS
PHMDGMLEEFRQVAARLEYHPPRIPVVSNVTGDLAGADELCTPDYWVRHVRATVRFLDGV
RALERAGVTAFVEIGPDSSLTALAQDCLEGRAELIPLLHRDRDEAESVTAALGRFHAQVA
TPGWERVFAGRDVRRVPLPTYAFQRERYWLDDTAGDGDVTSAGLVATGHPLIGAAVELAD
ADTYVFTSRLSLRSTPWLADHGVFEEALFPATAFLELAVRAADEVGCARVDELSLAAPLV
LPEDGAVVLQMRVGPQSADGTRSLEVFSRPQDAPADEAWTRHADGVLSPGATPVAPGAEA
LAEWPPPGAEPIDVTGLYEQFAESGFAYGPVFQGLTAAWRRGDEVFAEAALPASQRSEAG
RFGLHPALLDSVLHSLAFGVLSGSGQAWLPFAWSGVTLHAGGAAAVRLRMAPTGDSSMSV
ALADGTGAPVATAESLALRPAAPARSATGAGRTHRTLFRPEFTEVPLPAADAVPAFEVRC
YEPGQDAEAVRRATRRALADIRDWLGADRAGAKLVFSTRGAVPLTADDDVSDLAGAAVWG
LVRSAQTEHPDRFVLVDHDHDHDDQAWADAAAAYAVACGEPQLAMRDGRAYAYRIARVPV
GTADAAPQWERGGTVLVTGGTGAIGAHVSRHLVTEHGVKRLLLTSRSGMAGRSAARLHEE
LTALGAEVEVASCDVADRDALAALLAAVPSEHPVTAVVHTAGVVQDGIVASITDEQLDFV
LRPKVDAVLNLQELTAGLDLSAFVVFSSIAGVFGGMGQANYAAANAFLDALSHRRRAQDL
PAASLAWGLWANDAGMSGHLNENDFKRIARGGIIAFPPAEGLELFDTALAEDHPVLLPLR
LDTKAVQAQGEVPAVLRGLVRATVRRGAADTATGAAEAAGLAQRLSGMTDTQRDRALLDL
VRDHTATVLGFVDADSVDADRGLMEAGFDSLTAVELRNRLGAASGLRLPATLLFDYPSCR
AIAGYLATELVPEPAAAGQLPGLAELDRLTTLLDDERYREELTGRLHDLLAKARAAAGDD
FVEERIDAADDDEIFDFIDNELGMS
>A0A139XLM1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii ARI|TrEMBL
MMTRLPLCQQQAPPSLAGCHMLAAFQDIPERPLNRDLKELWAAYGENPFGNVLECWNRSI
PDEDAVVWLNSDGEISETTTFSELFSRITRLSSFLRAAGLQVGDRIILCYPPGTDFVTAF
FACITSGFVAVPVYPPDPSKGLSDVPRFCDINEIAGCKTALTNSLYKRVVQVITTVAKDS
RWRSVHWVCTDDVIKRHAEEAKNSVGPDFPNLSPHHPAFLQFTSGSTGNPKGVIVTHGSL
LHNCHLCWSAYQFPSHYENDGDDENITNHDFALVNQREFWRRRQEISIKSRGHRLRAFSW
LPVYHDMGLIGFVCSPILCGATLYQMSPIDFIRRPWLWLQGMSKYDCICCAAPNFAFEVV
TRKMPDNVYEHLDLSRVCGFLSGAEPIRASTIDRFCEKFGPKGVRRCAVCPAYGLAESTL
IVTARKTFQTVPKLLIVDSFQLQHEKTVVALTPEATVTMDSEEYQVLVGCGVPLEGVQVR
IVDPETKKELPPGKVGEIVVYSSSVARGYFGRPDTTKETFCYSFTDLQGKQTPPLGMRTG
DGGFMYEGELFVAARLKDLIIIRGRNFYPQDIEEAVDKVAMVRPGSSAAFAIEVDGHEAL
AVAAEVRLEEGIKGLWLRVKRQFDRSHYEQIVRDISKSVAANTGLTIHRIWLLRPRTIPK
TSSGKVRRSLTKEKLVSGKLEGILLDHAHHQHQAFYHDGPGGSRSRTRTGSGATPSGGAA
TRDGTASSNPSGDAHPKNSNTSNSITDSSHSVQRGSLRGDACVAGGRLGPSASHGGVHHE
KDHKHRGDGSGMSSPDQVPGAGAAASESSAHAALTEKVKQTVFEAAKTVLGSSEIPEIDA
PLHELGVDSIGAVEFSELISAELQVDVEPTLLFNYPTLSDVIDFFVRELEGKGSEDLAVS
LEKTGARETTTAIIGAACNLPGGTTSLNAFWDLLMCGVDAIAEVPRSRWDVEEYFDPDPG
ADGKAYVREGGFIEDAEMFDAAFFRISPSEAKSMDPQQRLLLEVAYESLYDSGYTREGLQ
RASVGVFVGCCSNDWYQVCSQLELGISSYTTTSYAPSIIANRLSYTFGLLGPSMTIDTAC
SSSLVALHIAAQELQGGSCMSAVVAGVNLMLSPHITVAFCKSRMLAPDARCKTFDASANG
YVRGEGLGSIVMKRLSQAEKDDDRILCILRGTAVNHGGRSASLTAPSGPSQQRVIRTALR
QAELTPGDIYFVETHGTGTSLGDPIEVGALKSVFGASRDAKTKPLILGAAKTNIGHLEGA
AGIAGVLKAMLALRYKHIPPNLHFKQMNPHIDVREFNVVVPTAPMAFPREDGGRLFAGVS
SFGFGGANGHVILQEALQQPSGDKPPCKRHSKRSIICFMFTGEGYEVSCMGRHLYETDDV
FKEIITKCNDILKRWLNVSLLSILYPPADKKMEMDKMMCQARFGHTALFAFEYALAESMV
SKGVKPDVVFGVGLGELVAAAFSGVMSLEEALYVVTQRAKLIDNLPPFEGVMVACRVSEQ
EVEMALSEMEINSRQSISIAAVYGRKNLILSGEQSEIDNVLMKLNIAGRWKYLPVHNVLT
MNLVSDIIPPFTHLMSTVKLCRPKVRLVSSTTGEFVDKEALSGRFWSRQVSQTVQLQQAV
ENIVASGCSLFVEIGPQVVLTKLAQQSLNGNAKDVTWVPAYDTTSDDVRVFENAVMTCNE
AIKIIGKERSLEEGQHGQEELIFHRKPFPWTEIPHPFLSGHKFTEKDDVVFENAFPRRAI
PLIADHAVNGTAMMPGAGMLEMVGAAALALDLRTTSGAVSLENISFERPMLIGAHRVTYE
YNRRHSLGEGGGAGTSPRTVRTPRLVNHAYTRLGFREKSAEKAISETAGPASTEGGRTPV
AGHHHGSYTKAGVLEDIKDYAHNVLRRAAQHAEEIDVHTPVPPSMAPPSIVARHPREGSY
GSMSRTSGIMGSNDRGDGLTVPLSVEMAIRCRVTKMKEVELSTVWDDEVTDHCFATIVIA
DKKQETYSSLQEVRCRCTERMDVNEYYDMLYDAGLQYGPRFRTIQELYRGEKEALARVHF
VGNVKQDPFESGFLIHPAVLDGALQAAGCLLEQSHSGNKVMVPVSVGSATLTKVEVFQPC
WAHVRLEETKSKAATLNVTIYDEVTREVVASLQNAVLRQVDPSASVVATIPKELLWKVNW
QLVVEGDKEVVGRTPKVLFIGGNIELSEALENAMGSTCKTLSVDALPREKAELQKVLDAE
QWQAIVYVEAVTAGVYDALDVMNAAVRLVQAHYLNLNSGKAVGALWFVTRDTVFRDNGAD
KPGVEIPAHAGLWGLAKAARLEMEVSAGSPISMGCLDVSGADVSSMAQQILHALKSKVLT
MRETEVAVREDGLYVSRLAPQTEVDVRGAIEFHMPERGAISNLVLRPQAFASRLPPEDGQ
IELRVRAVGLNFRDVLNVMGLYPGDPGPPGADCAGVVVAVGDNVEHIEVGDCVFGVAQGC
LRTYVTTDSQLLRRMPESMTFEQAAALPVVATTVEYALHDLAKVKAGDKVLIHAVTGGVG
LVAVQLCKRVGATVYGTCSGGKKDAFAKSMGVQYVSSSRDAKAFAEDMRTFLGEDGKVDV
VLNCLIDDFIPESLKLLGPYGRFMELGKRGVWSKEKVAAERPDVQYELIAVDEMMEKDPI
WFGGMLVRVRGLVAEQKIQPLPMHVFDLADTGENGGVAAFRFMQRAQHMGKVVLKIPSPV
EEASKNGSIVITGGLGALGMVVAGWLAEEGARHICLLSRREEAPQPGEIPGWDWLRTINC
DVQFFSCDVSKYDSIRSVLRTIQTSVAPITGIIHTAGALADALLDSQTPELMKKVYNGKV
QGAWNLNRALEELGLNEQLKLCVFFSSVTSLFGNFGQANYCSANACLDALAQWRRAKGLC
CQSIQWGPWIEQGMAAELKQQVERNGMKGISNEVGLRVLHDAIRQQEKATPVIGCQAIKW
KLFMHRYIEQPPFFTNIEMDLQVTSHDSNTVLRNLPPSERRDYIKAQVAAAARQVLGSSS
PPPFDTPLQDVGVDSLGAVEFRNVLSKKLGVKLSATTLFDYPTLNAIIDHLCEVFGESSQ
KDNLSTKLGALSENDLVQEGMAIVSMSCRLPGNSTCPDLFWDMLMRCTDCVCDIPLTRWN
AEEVYSEDPDLPGKCYTRRGAFIENAEYFDNSFFGISPSEVKHMDPQQRLLLEVAYEAFA
GAGLTKEKLLGANIGVFVGACNHDWTYLIQEDKISAYTGTGSAGSVIANRVSYCLGLRGP
SVPVDTACSSSLVAADFAFEKLMLRDCTMALVTGVNLMLTPHLFIAFSKARMLSPDCKCK
TFDASADGYVRGEGAGAVLMLPYADAKAKQMTIQAVVKGTACNHVGRSASLTAPNGPSQA
EVIRMALRRAGMKPNDLKFMESHGTGTSLGDPIEVNAVRTVFAPGREKTKPLLIGAVKTN
IGHLEGSSGIAGLIKACLVLSRREIPPNLHFKTLNPHINIEDFPVQFVTDFVSLDSVEST
RKKNTAGVSSFGFGGVNAHVLLEEATRDQNATRKEENRPKICFMFTGQGSQYVGMGRHLY
EKEPVFREAITRCVEIAKEYLPLPLLSVIYPSPDERDKMQEAINETLYSQPAVFVISYAL
LELWKSRGVEPDMVMGHSLGEYIAAVCSGVISIQDGLKLVLKRAQIMSRAPSRNGVMVAC
RATAEQVEEAIHTLFGDGEKNVALASVNGLKSVIVSGNQQDVQAVLRQLGAASRAKMLRV
SHAFHSPLVKDTVAPFKRVLETVRLSKPRVMFVSTVTGKVARDELQNTNYWAEHITKVVR
FCDAVQACIAQGAKIMVEVGPRPTLSNMGKGCLPQTTADEVQWINSLEPETLSSAVFDSL
SALAKAGSGAMPAVFDRKFFPWTETCHPLLGGKNTRPDGSVVYSALLRDLVKALFLDHVV
YGKALLPATCLIEMMASATTHMISNHDEEKLVALSQVVFEKPLLVPDETSLSVLVTVETR
GQVRVASQVSNSEEEAEDHAVCQVNIVDALPAAPALTEIRARCKTEIEASQLYAQLHNVG
LQYGPRFQTIVKVFKGEDEVLGLLQAQNVTNFETGFMMHPAVLDGALQLSAVLAFEKGSS
RAMVPFGVDTVLLKSCPPEKELWARVVMNRKGVSSASATVHLYDFDGEPIAVLMGVTLRP
IEFNTAADIPRELLWEVEWESAGSYSMPQDGSLATPSGTDDSGAEDVTRTPSPLVTGENE
NTPSREVPSALPGLSTETPRASKPLSTDETSGAVLNKSVHSVLLVDYAGGHREVVASIRD
TCDVEVEVLSKPWSPELYAQQLRQFAEVVATKTETVPLSTILFLALDEATPAEQLAGGLL
ETVKVFAVEKFKKLPCIWVLTSGAQGPTRSVVSPKHAGLWGLMRTVRLELEMQIGKMVRF
GCVDLDKNLEVSVALHFILQKRTEEPFEAEMILRCPSEDSEKEPGTAEVVNRRERSASFV
SVGPEPVVPSTTDASAKSSVTSDRMALTPGALSCFDETANSTEKLIFNAFCPRLHRSPIP
VRGAVELHMPERGAISNLVLRPQAFASRTAPQSHECEIRVRAIGLNFRDVLNVMGLYPGD
PGPPGADCAGTVVAVGSGVRHLKVGDSVYGIAQGCLRTYVTTNGNLMRRMPESLTFEQSA
ALPVVAATVEYALHDLAKVKAGDKVLIHAVTGGVGLAALQFCKRVGATVYGTCSGGKKAA
YAKSLGVKYLTSSRDASAFAEDMREFLGEEEKIDVVLNSLIDNFIPESVKLLAPGGRFME
LGKRGIWTKAQMAAERPDVYYETIAVDTMMQEDTVWFGGMLDRIRDHVDSGNIPPLPLHV
FEMTDPLAGGVAAFRFMQRAQHIGKVVIRIASDLEVKIPSTTEPAATETAMLAEAGTQGN
ASIGTSTQQIADRTYLITGGMGGLGLVVAQWLVEEGARHIVLLSRRGEPSDTVKQSSIWE
YLTEKERTCVSVLPLKCDVSVKDDIVSAVKEIEARGFP
>A0A517NCR6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Rubripirellula lacrimiformis|TrEMBL
MLFGPLDPNLLFHFPGWVTVRAIYQQEYGSPQTLALTELERPSIRRDEVRICVHAAGLHI
GDAFAVRGTPFLMRMETGWRRPRYGVPGFDVAGVVESVGANVKQWKPGDAVFGACKGSCA
ELVSAKQDHIAAKPNNLTYAQAAALPTSGLAALHALRNVARVTAGQKVLINGASGGVGTY
AVQIAKAFGAGVTGVCSDRNAGLVRSIGADHVIAYDHSDFAAGQQRYDVILDNVENRSLH
DCRRVLAPSGILILNSGTGASGLSLLWRIAKPLLLSPFSRQRLRRYLSMPNRKDLETLTS
LIDAGSLSPVIDRCYTLDETASAVQHLEAGHARGKVVVLVQSDSETAGTEP
>A0A1Y2NJ39|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces platensis|TrEMBL
MADEEKLVDYLKRVAADLHDTRQRLREAEEKGRQPLAIIGMNCRYPGAATPEQLWDLVAA
GGDPISDFPADRGWDTDELYDADPEKSGKSYVKQGGFVYDAIDFDAAFFGISPREALAMD
PQQRVVLEAAWAAFEDARIDPSSVRGSDTGVFFGASGAEYVPVIQQLPDASEGYTMTGVA
SSVLSGRVSYSFGFEGPAVTVDTACSSSLVALHMAAQALRQGECSLALAGGVTVMGTPGV
FTSFSRQRGLSPDGRCKAFAAGADGTGWAEGVGVVLVERLSDALRNGHPVLAVLRGSAVN
QDGASNGLTAPNGPSQIRVIRRALENAGITAAQVDAVEAHGTGTTLGDPIEAQALLATYG
KARSTERPLWLGSVKSNIGHAQQAAGIAGVIKMVMALRHRVLPKTLHVDAPTPHVDWESG
AVELLTEAKPWESADHPRRAGVSSFGISGTNVHLILEEAPDAEAAAPAAEEPPARTPGLA
ATGTVPWILSGATAGALRAQAAQLRAFVADRPELDPATVGYSLATTRAALEHRAVVVGAD
RAELLGGLTALEHGEPAGNLVEGIAGSRGKAAFLFPGQGAQWAGMAVELLDSAPVFAARI
RECETALSAFTDWSLTDVLRGAEGAPGFDRVDVVQPALWAVMVSLAALWQSCGVTPSAVV
GHSQGEIAAACVAGALSLEDAARVVALRSKTLIELAGHGGMVSVPLPLDQVEERLRAWGE
RLSVAAVNGPGSVVVSGEPQALQELLDGCAADGVRARRIDVDYASHSAQVAQIRERLLEV
LAPVRPRAADIPVYSTLTGDWLDTTTMDADYWYRSLRQTVLFEPAVRGLLDAGYGTLIEV
SAHPVLALGVQDTIEATGRSALVTGSLRRDEGGVARFLTSLGQVHAHGQSPDWAAVFAGA
AHGTAALPTYAFERQRYWPKGTMTAAGDAAGFGLSAARHPLLGAVVTLADDEGVLFTGRL
SLSTHAWLAGHVVAGRAVLPGTAFVELAVRAGDEVGCEVLEELTLAAPLVLPDRGGIRLQ
LAVGGPDGSGRRELSVRSRPEDAPDEEPWTTHATGTLATGAGAAVPRAESWPPEGAEPVE
CDGLYERFEGTGLSYGPVFRGLRALWRRGGELFAEVALPEAAEDEAAAFGLHPALLDAAL
HPLALGGFVEDGSGDRPWLPFSWSGVRLHAAGAGTVRVRLSPTGPNALAVTVADATGAPV
ASVASLMLRQLTSDTLDATGPTFHDALFRVDWTPAPVPTETAGGTVALLGAAGPDHRAAL
EAAGARVDEYPELAALLRAMDAGAPVPDAVLVSCAPPEAPEITAAVREATGRLLTLAQDW
LAEERFADARLVIATQGAVATEPGADLTDLVHAPVWGLLRTAQSEHPGRFVLLDSDGLET
SARALPAALALGADQLALRAGEIRLPRLARMAVSAAPAPEFTPGGTVLITGGTGTLGALF
ARHLVTEHGVRHLLLTSRSGSRAKGAAGLTAELRELGAEVEIAACDAADRTALRALLADI
PADRPLTGVISAAGTLDDGVLESLNQERLDAVMRPKVDAAWHLHELTRDLDLAAFVVFSS
AAGVLGGSGQANYAAANAFVDALAAHRRAVGLPALSLAWGRWTEASGLTEALDEAALARM
SLSGMTGLSTAQGVALFDAARAAGDALLVPARLDLAALRQQAGSGMVPELLRGLVRMPGR
RQVDSGAAATSELRERLTGMSAAERDRTLLDLVRAQVAAVLGYAGPQSVESARPFKEIGF
DSLTAVELRNRLGAAVGLRLPATLVFDYPTPLELAGFVRDELLGAAAGTPAGAPAAVRAD
EPIAIIGMGCRYPGGVDSPEKLWQLLTSGTDAVSAFPADRGWDMERLFDPDPDHPGTSYC
TEGGFLYDAARFDAGFFGISPKEALAMDPQQRLLLETSWETFERAGIDPAALKGSGTGVF
AGVMYNDYGMLTAASEQLDGYVGVGVAGGAVSGRISYTFGLEGPAVTVDTACSSSLVALH
LAVQALRQGECSLALAGGVSVMATPGTFIDFSRQRGLAPDGRCKSFADAADGAGWAEGAG
VLLVERLSDAVRNGHPVLAVVRGSAVNQDGASNGMTAPNGPSQQRLIRQALANARLNADQ
IDAVEAHGTGTTLGDPIEAQALLATYGQDRPEDHPMWLGSIKSNIGHTQAAAGVAGVMKM
VLAMQHGVLPRTLHVDRPSTHVDWESGAVELLTEAREWPETGQPRRAAVSSFGISGTNAH
LILEQPSAARTPAAPGTGPAPAVLPWVLSAHSAQALRAQAGRLAALAEGDPDPVDVGFSL
VSTRSALRHRAVLVGDRAALLTGARALAAGTHPAGVVSGVAGEGRIGVLFTGQGAQRLGM
GRELHAAHSVFARAWDEVCAAFDALLPRPLREVVWAAPDTLEAALLDQTQYAQAALFAVE
VALFRLVESLGVVPDALLGHSIGEVTAAHLAGVWSLADAAKLVAARGRLMQSLPAGGVMV
AVRAPEDVVLPLLSGQVSIAAVNGPEAVVLSGAEAPVTALAATLADKGYRTKQLRVSHAF
HSPLMDPVLDEFRTVAEGLTYAAPRLPVVSNLTGRLAEPDQLRDPGYWVRHIREAVRFHD
GMQALHTEGLDTFLELGPGGVLSAMGQESLPGGEFLPALRKDRAEDEALLQALAGAHVRG
AAVDWLPLCDGGRRVALPTYAFQRQRYWPEADGPAGESRPDASDPVEARFWELVEQEDLG
ALLRTLDLDENQPIGALLPALSALRRGESAADGTRYRADWHVVSELSTAELSGTWALLVP
EQHLEGDCARSVAETLRAHGAEVRQLTVTGADADRERLAGLLAGLPAGIAGVVSLWALDE
QPHPEHPSVPSGVAGTMALTQALDDAAPGAPLWCLTRGAVSLTRTGRTAGTAAALVWGLG
RAVAAARPGHRGGLIDLPDTLDARQGAWLAQLLADADGEDELALRPSGVFARRLGHAGRG
AAHRPWRPTGTVLLAGELGAAGPPVARWLARNGAAHLLVPPALAGESPGVPVTVIDEALT
DRQALARLLDRVPAAHPLSTVVHGLGGAEDQPVGSATVAQFGQVLERAVRESENLHELAR
DAAAFVLLAPAASTWGDPSQAAVTAAGAYREELVRRRRAEGLSGTVLCWDGASSPESVFA
RAVECGEQSVTVAEADWAELAVTRTGSLLRALPEVRRPAQEPAADTGDEVDPEALRAYLK
ELDAAGRQETLLEIARGVAARALGHESAAAVEPDLDFLDAGFNSLSAVEFRNALNRITGL
SLPAALVYDYPTPNAVVEFLESELA
>A0A1K2G0Z4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. F-1|TrEMBL
MANSEAVTRIPEDRFNIDDHYSGRAPSPGKTVSRDGGFLDDAFSFDAGFFGISPVEAKSM
DPQQRILLHVVWEALESAGIAPSSLAGSRTGVFVGQATAEYGESGQPADGPGVRDTVGGR
LRAVTAGRVSYALDLRGPSLVLDTACSSSLVAVHTARQSLLTGESGLAIAAGVNIIVSPQ
DSIAYSQGGMLSPDGRCRFGDASADGFVRSEGVGAVVLKPLPDALRDGDPVLALLLGSAV
TNDGQGSGLLLKPSVSGQAQMLRDACHSAGIEPAQLDYVEAHGTGTPTGDTVELRALAEA
TGGERTLRCGSVKTNIGHAEAAAGIAGLIKAVLIARHGVIPASLHLTDPHPLLTGERPAV
SVVTENTPLDKAGPQALLGVSSFGLSGTNAHVVVGEFVDDRRPAEPVVPAVPGPRLLVLS
ARSAAALRRLAGAYADHLGPGGAGREQALADICATAATRRDAGPHRLWATGTSHDELAAV
LRALAAGEQSPHGGVGEAGFSGPRRAVFVFSGQGSQWLGMGRDLLASNEAFRTTLRACDQ
AIREELDWSVEELLTADADRFPGGVEIVQPALWAVQVALAAAWRDLGVAPEMCVGHSMGE
VAAACVSGALSLRDAAAVICRRSRLMRRVAGGGAMLVVELSADRAREAVSRIPSVCVAAE
NSPTCTVLAGDPEALAELTARLEADGVLCRPVNVDVASHSPQMRPLHSELASELAGLAPR
AAATGLFSTVRRAELAGPELDPGYWADNLCEPVRFREVVSDLAATGTVENVFLEISPHPV
LTASVAETLAHDGAPGTAVPSLRRDTDETAELVRAAGRFFAAGGRIDWTRWYGHPVRPVP
LPHYPWERTEFRQVSAAPHPARTVLEGRVELGRWGFAAWAEQLSVAGLTVLPPAVQIAAV
LDTAAEKLPGTMYAVRDVRLAPAPVLLPDPSAAVLAVALERGGDGWRAVVELERPDSTER
TFCATASLIPVDDSDGRRAPRELDGALARCHTYLSAAGFRELAGSYGLEIGETSGAVEQV
WHRRGEAVARIRLAKPAPGLWEVALLPLVAAWPQARRGEEDRGFVPTGFDSVQLYGELTD
DLWSLAVVAPGSDARQARGDVLVLDGDGRVLAEFRGIALRRPGRPAGPAASLVRALPARL
GAPRRGPARPLLSRFATMIRPPATRRALRLGEAPARPAAPVRADHRAAAPAAVPVAGGTE
AAVAPDTVTVRVDPADAILTAASEVLGVARADLDPRRSLRDLGLDSLMALQLRKRLQTGC
GVEITAGRLLGAESLERIVRDLAAAPTPV
>A0A1K2G279|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. F-1|TrEMBL
MVAVQASEDEVLPYLTEEVGAAAVNGPQSVVVSGVENAVLAVAEVFREQGRKTSRLKVSH
AFHSPLMDPMLEAFEQVVRGLSLNEPRIPVVSNLTGRLAESYTPEYWVRHVREAVRFADG
VGTLHELGVSTFVEIGPGGVLSALAQGCVDDVVTIPALRADRPERAALVAAVSELHVHGV
SPDWNAFFPGARRVQLPTYAFQYEHYWLDCAPAAPGAVRAAGLGSADHPLLAAAVCLAGG
DERLLTGRLSLRTHPWLRDHAVLGTVLLPGTAFVELALRAADEAGCALLEDLTLEAPLVV
PEHGGVAVQVWVGAADDAGRRPLTVHARPEGDTDLPWLRHATGFVTENTLAAAVGDTGAP
GPTAERGAPAAAGRPLTAWPPPGSTPVGLDGHYDRLAALGLAYGPVFRGLRNVWRAGEEI
FAEATLPDGTDAGSFLLHPALLDAALQAIGAGGPLVTEADGPLLPFAWSGVSVHATGAST
VRVGLAPAGADAVSLTVADATGEPVASVESLTLRAVSARQLRERADDALFTVERAPLALP
AGDADGPVVAYVPDLAALTETDGAARPDVVVVPCPDGPEGTGEAERIRAVTSEVLRLLQH
WLADEPAARLVLVARPDDLAHAAAGGLVRSAQAEHPGRIVLLETDRPDEAAVLAPRAVLS
GEPHVVVRAGEPSAPRLTRAASPTTADGPAPHLGTVLLTGASGALGGTLARHLVTGHGVR
RLLLVSRRGEDAPGATDLVAGLAALGAEATWAACDLADSAALARLLATTPVDSVVHTAGV
LDDGVLAALTPPRLAAVLAPKADAVLNLDELTGPGTTFVLFSSAAGAFGNPGQGNYAAAN
AFLDAFARRRRAQGRPTVSLAWGPWAQEGTMADTLDEAGRSRMARSGVLPLPTEDALRLF
DAALVSDKPVLVPVRLDTAALRDRAAQTAPALLRGLVRVPPRGTARRAATGSPAERLAGL
TGEDRDDALLDLVRGEAAAVLGHSSPGAVQPTHAFQDLGFDSLTAVELRNRLAAATGLRL
PATLVFDHPTPTALARHLGTELPGAAPAVTKATTTERPTAAADEPIAIIGMSCRLPGGVR
SPEDLWRLVAAGQDGITRFPDDRGWDVEGLYDPDPEHLGTTYARHGGFLHEAAGFDAGFF
GISPREALAMDSQQRLLLEASWEAFERAGIDPATVRGSRTGVFTGLMYHDYGQGPRALPD
GVEGLLTTGGSGSVASGRVSYTFGLEGPAVTVDTACSSSLVALHLAVQALRTGECTMALA
GGVTVMASPTVFVEFSRQRGLSPDGRCRAFAAGADGTGWGEGVGLLLVERLSDARRLGHR
VLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLSPADVDAVEAHGTGTRLGDP
IEAQALLATYGRERPEGRPLWLGSLKSNIGHTQAAAGVAGVIKMVMAMRHGVLPPTLHVD
EPTPHVDWSAGEVRLLTEAVDWPGTGRPRRAAVSSFGVSGTNAHTIIEQAPAAEEPSSPP
PDPGTPVPWILSGRTEAALRAQAARLASHLDDNPLLDGNSRPGGDDRDCDDDRDCDDDSG
CGDDSGRGAGRAADVAYSLATTRADFEHRAAVVARTPEEFRQGLAGVAAGTTPPGVLTGT
AHTSGRTVFVFPGQGSQWAGMATELLDTSPVFRDRIDACERALAPHVDWSLTEVLRGTSD
AEQDRVDVLQPVLWAMTVALAEVWRSFGVTPDAVVGHSQGEVSAAVIAGALSLEDGARVV
ARRSLAVLDLQGHGAMASVALPHEEARELIGRWAGRLGIGAVNGPGTVVVSGDTDALDEL
LAHCAQQGVQARKVAVDYAAHSPQIERVEARAHEGFAPVEPLPGTVPFYSTVTGGRLSPD
ELGPGYWYRNMRQTVRFHDAIRAALADGHDVFVEVSPHPVQLAGIQDAIEAAEARAAIVP
TLRRGDGGRHRLMLSLAQARLHGVRVDWDAVLPGARRVDLPTYAFQHERYWLAAGAAAGD
VRAAGLDTTGHPFLGAAMELPDAGGHLMTGLLSLAAQPRLAEHAVLGTVLLPGTAFVELA
AHAAAETGCDLVEELTLEAPLILPEQGGVALQVLVGGQDDSGRRPLSVHSRAGDGPWLRN
ATGTLATGAPSRGTDLGDWPPADAEPVDLDGFYDRLAGLGLSYGPLFQGLRAAWRGPDAV
YAELALTDEARPDADTFALHPALLDAALHALGAGGLVPAADGPLLPFAWSRVTLHGTAAA
GLRVRLTPADGDAVRLEAADDTGRPVLSVDSLTLRPVSAGQLRTNSRDCLFTVEWAPLAA
AAADAHGPAVRVCDDIAALLAAPATPDGADAVVVPCPAGSGADAARVRDVLAEVLRLLRW
WVTEDRAARLVLVTRGAVATGDDPAADPVQAAVWGLVRSAQSENPDRIVLLDTTPDADTE
RAAATAVPRLLAADEPQAALRGDILLLPRLARATAETPASAPDFGSGPVLVTGASGALGG
LVARHLVAEHGVRSLLLMSRRGADAEGAAELGAELAAAGADVRWAACDAADRDALAQVLS
GTPVTAVVHTAGVLDDGVIDALTPERLDTVLRPKADAVLNLHELAGDVRAFVVFSSLAGT
LGTPGQANYAAANAFLDAFAARRRAEGLPALSLPWGLWQRTGTMTGDLGGADRTRLARGG
VLPLPDDDGLELLDTALASDDAVVVAARLDLAALRNSTAPVPPLLRALVGGRARRTDRTA
AVPAAQRIAGLPESERAAAVLDLVRSEVAAVLGHGSAKAVRPGQAFGDLGFDSLTAVELR
NRLNRATGLRLPATLVFDHPTPADLAQRVLDDLPGGTSPSAPVLDELDRLAAALDGAAAD
AVDNVTRTRITMRLRSLLARWNRDEPAEPADAGGAGTDDDLSSASDEELYDLLDDELGIS
>A0A379C0G6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia brasiliensis|TrEMBL
MGSGAIDRAAIEEWLSGRIGEIVGADPATIDRTTTFAAYGLTSSDAVGLSGELEEWLDRK
LPETLLYEHPTVAQLGAALADTSSAAAATPEQPAAAFATGGPSGEQDTICIAGMACRFPA
GANTPQLFWRNLADGVDAATDVPHARWDARRYFDPDPYAPGTAYTTRGAFVDDLAGFDAQ
FFGISPREALRMDPQQRMLLETAWAALEDAAIPADRLRESRTGVFVGMMADSRYAHLLVD
RGGPGELDDPYVGLGSATSVVAGRLSYLLDLRGPSMVVDTACSSSLVALHLAINSIRVGE
CDRAVVAGVSAIVHPDTYLQACKMRMLAADGRCKTFDARADGFLLGEGCGAVVVERLADI
RARRHQARAVVRGSAVNQDGTSNGLTAPNRAAQVAVIRAAHRNAGIDAGSVDYVEAHGSG
TQLGDAIEIAALTEVFGPARVGVRPLYVGAVKTNVGHLTGAAGMAGLIKTVLALHRRTIP
RNLHLREPNPAIDWAASPARLPHENIPWPDAHERTPTAGVSSFGWSGTNAHVVVSAPPAL
VRADDTARRHILALSGRSPQAVSATAHALAEHLRSHPRLHPADVAATFQTGRSAMPYRAA
VPFETLLEAAEALDEVGRRVPVTAVPHGRAPTVRFVLPGTGDQFAGMGRDLYRAEPAFRA
ALDHCAEIAAAPLGMDLRTVLYPDSAPAPSDPFAALRNRGSTALPADELVSRTDLAHAAV
FALSYAAAQLWRDHGIEPTGLLGYSLGEYTAACLAGVFDVEVALPLVVRRAQLVAAAAPG
AMLTVAMGVHRLADYLGPDLSCAAVNSPGTVVVAGTEAAVAALEQRLAADEIAALRVPTT
RAMHSHLLEPLRAALIELFDGVELRAPRIPFVSNVTGTWISDEQARDPHYWAEHLCATVV
FDEGVQTLTGSDPCVLVDLGAGQLASLAAQTLAHSDGALTLPTLRAASLRDPDDQVVART
LGRLWAAGVDVDWSEVGSAGTSVSLPTYSFQHQQFWPEACAARPVREPGPARTGTIEVLE
PQWVGTRVTDGANERSGPYLVFTDPETCSAELARHLVKALGGADVVTVSPGTEFATTTAG
GYQLRPGASGDYAQLMTALADRNLLPRTVVHLWSVQGPQEDPVSVDGVGAHRRLGFDSLL
ALAGDLSRHCADGCRILVVTDHAQTCDPEDELYPGKTTLVGPARTVGQEYPGLAVRTFDV
VTPAEDASASWSELAESVVAELDWRGSAAVVARRGRRRFVQRFQPRTLGEAEAYVRDGGV
YVITGGTGSIGLQMAAHLVAAGSGLKFVLLARTPLPDLDDPASLAQASATAHERAAAVRE
LVRAGAQVLVQPCDIGDRAAAAAAIALARKRFGPIDGVIHAAGVLTPDAFTTIEGTTPEL
TAAHFRAKVDGTLALAHALRDERPDFVVLLSSMSAVLGGIGFTAYAAANAFQDQFVTLRG
LPGGSAWRTACWDTWQATVRHGERPCVAASLDTYSFAPADALAVFDRLIAGGPRRAVVSA
GQLRERLAAWVRAGDPLDSSVAPAAAPDRTVEDYRRELARLWQTALGVDQVGLHENFFES
GGNSLVGLQLINAIKKQFRVVVPTVALFEAPTVAEMADYLLTATAPERKSRT
>B2IXI7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MEEFAQNKIHKIAIVGMDCYLGGGCKGLDTFERSIYEGTQHFISRPPQRWQAIEAQQQLL
KNYSLPDGVAPLGAYIKDFEIDTFSLEIPPEEVDNFNPQELLMLQVADNALKDAALRKST
RIAIIIAITKDLTLHQQKEQVEDNEYTDYIENSPANYISKLWNFAGPTFTLIAEQNSVFK
ALELAQKLLAIREVDAVLVGAIDLAGDGASVLQRNEITKVNTGVNTLSYDQKANGWIVGE
GAAAVVLKLHETAKRENNRIYATIDALSLVENSKSKIHSLTVPNSEMIAQACQQAFHLAD
IKPRDINYLEVVGSGIPQQDESEIQGLLAAYRTFEPNLTCAIGSIKANIGHTYAASGIVS
LIKTALCLYHRYIPAVPQWSGPKMPEIWRDSPFYVASESKPWFLEKGATRRIAAINGMEI
DGSYAHLILSEEVYQQHHSSRYLEQMPYYVFAIAADDQSTLLEEIRTLQQTIQNCSSLST
AARLTFKAFQQHQQATYAVAILGHNQDELQREIQHSLKGIVNAFKTGKDWQSPLGSYFTA
KPLGQKSKIAFVYPGAFSAYIGLGRNLFRLFPQLYDDPFIRSIYNRVANVEKLIYPRSLE
KLSNRQLEVLEQQLLNDSVAVLESEMACAGLMTAILKNYFQLKSECAFGYSLGEISMMLA
QGVWTQFQEGSEGFNSSSLLKTRLSGEKNAVREYWGLPQEQNQQGEDFWRNYILMCPVSR
VQETIKYENRVYLPLINTTEEVAIAGEIQACQRVIASLNCNAFSAPFTHVIHCEAMRSEY
DELVRLNTLPSRNIPETIFYSAAEYKPIDLDSHSIAHNIAQNLCQQLNFPQLINRVYEDG
FKIFLEVGAGSNCSRWIDKTLNAKEHITVSLNKRGVDDHASIIKALAKLLSHRVDLDLSP
LYSQEPEIFNQSQPSVKTITLDNTKISYTSLNKKNQEILQDISFRYPIKTVNQQQSQLSE
LKEFPKMNSSLLSNPTKSLENTSRNLESLQEQVNFQNSSQPTQLLLQERNESVEKLQINE
NLVTEQENNQFALTPSLKTSSIVDETNLLNLHSPYYQKLSENASRMTKAHAVFLQARQES
LKQISVIIQLQIACYQKLFES
>B2J0Y6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MMNQPNAFDSLDEIAIVGMNGRFPRAKNIEQFWQNLRDGVESISFFSDEELLSSRIDPAT
LSQPQYVKAGSVLEDIELFDASFFDFSAKEAQITDPQHRLFLECAWEALESAGYNSEIYA
GRIGVYAGASLNTYFLTNLYTQPKIIESVGSYRISIGNSPNFLPTYVSYKLNLKGPSLNV
QTACSTSLVAVHLACQSLLNGESDIALAGGVSIQVPHKTGYRYQQGGIMSPDGHCRAFDA
KAQGIISGNGVGIVVLKRLEDALADGDCIHAVIKGSAINNDGSLKVGFTAPSVDGQAKVI
AEALAMARVESETISYVETHGTGTVLGDPIEIASLTQAFRPTDKKNFCAIASVKTNIGHL
DAAAGVAGLIKTVLALKHQQIPPSLHFEQPNPQIDFANSPFYVNDKLSEWKSNGTPRRAG
VSSFGIGGTNAHVILEEAPVWEQGRQRRQGRKYHLLVISAKTKSALETATANLANHLKQH
LELNLADIAYTLGVGRRGFSDRRILVCQNLNDAVTVLETPVSERVFTKFTEPSGQQIAFM
FPGQGTQYVNMGRELYETEIIFRKQVDYCCEFLKSYLKLDLRTLLYPHQQTEALTQQLQQ
THITQSAVFVVEYALAQLWMAWGVRPNAMIGHSIGEYVAACIAGVFSLEEALILVANRGQ
LMQQLPSGTMMAVSLPEKKIQPMLGKKLSLAAINAPDMCVVSGLEEAVDDLQKRLIDQGV
DCHRLHTSHAFHSSMMDSILLPFQEQVSKISLNSPKIPFVSNVTGTWITPAQATDPKYWA
RHLRQTVRFSEAIAELLQQPKRILLEVGPGRTLSTLANKQKAAQQVILSSLRHPQNQQSD
VAFLLNTLGRLWLEGINVDWSEFYADEERHRIPLPTYPFERKRYWIEPILANDDNLSPKN
EILVSQPEDIITNSIKVPDTQIVNQPIANTAIEQIISQHLQVMSKLVDLLPQGSLAREVL
PSLGAIHQDGQIAQTSTNGSAFSGNQSTFTKAESEQQIKDRKINPTPKAASQQIEKESMM
LSPRQQRHLDSLIAHFVKRTQESKRLTQAYRSCHANSRAVSGFFPFIKEMIYPIHAERGE
GARLWDVDGNEYVDISMGFGTLLFGHSPSFAIAAIQEQSKQGILNGPQSRFAGQLAELIC
ELTGAERTAFCNDGTEAVMAAVRIARSVTGRSKIALFAGSYHGGSDGVLVKGVRTNDGTL
RSVPMTSGIPSSLAEDVMVLEYGTPESLNILKDNAHNLAAILVEPIQSSRPDFQPKEFLF
QLRQLTQETGTVLIFDEVVTGFRMHPGGVQALWGIQADITTYGKAVAAGIPIGVVAGKAV
FMDALDGGMWNYGDESYPQVKTTFFAGTFFKHPLIMGVAWATLNHIKNSGSKLQEELNQR
TTQLAETLNSYFEQKQVPIRVVNFGSLFRFNCQTQLGNLFFYHLLAKGIYVWEGRTLYLS
TAHTDKDVEQVISAVKESVVEMQAGGFFTSEQTSKNSGQTSANQTLTGSSLNLATESLSV
TSNVKSADELFENLIEQIPNALGNTYAASRKKIEKTIADIWQELFGFDNVNIHDNFFELG
GDSLTALQAISLLNKKLDLDIPIESIYEAPTINSLTNIVCPEQNEILSAKQSISRGQRRR
EKRNQR
>B2J0Y5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MMNKLDKINNVDEADIAIIGLSGRFPKAENIEQFWQNIRDGVESISFFSAQELESAGIDS
VTVSHPNYVKAAVPLEDIDLFDASFFGYNPRDAEIMDPQHRIFLECACAALENAGYNPQT
YSGSIGVYAGSTISNYLFNLYSNPNIRELASDVEISLGNHPDYLPMRVSFKLNLTGPSYA
IQTSCSTSLVAVHVACQSLLNYECDMALAGGISILNMQPKGGYLYQEDGVLSPDGHCRAF
DAKAKGTIFGSGIGIVVLKRLKDALADGDRIHALIKSSAVNNDGSLKAGFTTPSVEGQTE
VIAEAIAAAGVEADTITYVEAHGTGTPIGDPIEIKALTKAFRVSTPKRGFCAIGSVKTNV
GHLDAAAGIAGLIKTILALKHKQIPPSLHCEQPNPQIDFANSPFYVNTALSEWKSDRIPR
RAGITSLGFGGTNAHLIVEEAPPIEASNVGKTHKLLMLSAKTNSALETATVNLTNHLKQH
PDTNLADVAYTLQVGRQTFNHRRILVCHDIDDAVEALHTLEAQQVFTHYQQPCNRPTVFM
FPGQGAQYVNMGRELYHSEPKFTEEVNRCCLILKPHLGLDLRDILYPSEAQTQTATQQLK
QTSIIQSALFVIEYALSKLWMAWGVLPEAMIGHSLGEYLAATLSGVFSLNDALALVAARG
RLMQQVPTGAMLSVQLSEQEVQPLLPKELSLAGINSPSLCVVSGSTDAIDKLQQQLLEKN
ISCRKLHTSHAFHSQMMDAIIEPFTELLQKVKRNPPQIPFISNVTGTWITTAEATDPHYW
ARHLRQTVRFDEGMTELLKQPERILLEVGPGQTLSTFAKQHYNLEPVVLTSIRHPQEQQS
DVAFLLNTLGRLWLFGFQVDWSGFYANEQRYRIPLPTYPFERQRYWISPQAQPRDVHATE
VSLNKKPDIADWFYLPLWKQSAPPELLGKGDLAEQKFCTLVFTDECGLGSQMVKRLEQQG
QDAIAIQIGSEFSKVSECLYTLNPRQSNDYDALLNELLVQNKIPKTIIHLWSVTPDYHAE
SELEWFDSAQYLGFYSLLFLTQALGKQNWTDKFKITVVSNNIQSVTAEEMLCPEKATVLG
PVKVIPQEYSNISCRSIDIALPKPGSWQEEKLVDYLLDELQTKSSKLVIAYRGLNRWVQT
FEPVRLSESKGKTSRLRNGGVYLITEGLGNIGPILAESLAQTVQAKLVLIGQKNLPEKDE
WFGWLNTHDRQDEVSCKIRKLQALEELGAEVLVLSADVTNLEQMQRAIAFVTEHFGDIHG
VIYAVEIVDDKSLKSIQETSQTDYQCHFQSKANGLFVLEKVLQGRQLDFYLLISSSSSIL
GGLRSVAYSAANIFMDIFAQKQNQINPVPWISVNCERWELGEEKNTASRTTLAELFITPE
EGIKAFQRILTSDKITQVVLSAGDLQARFDQWLKLKSLSDVEQTSFAGDIKKKLASTSLA
KILHPRPNLGNDYVAPRTHTEQTLANIWQEILCIESLGINDDFFELGGHSLLAVHLIAKI
NNQFGKNIQLSAIFQSPTIKQLANILHDRADYRTSSPLVAIQPHGSKPPLFFVHPVGGNI
LCYYELSLHLDSDQPFYGLQALGLNGESQPYTRIEDMAAKYIEALREIQPNGPYFLGGWS
MGGIVAFEMATQLLRNGDRVAMLAMLDSPAPVNSKEIAEIDDYNDVKILVDFATDMAQSA
GKNLSGSVEQLQALMTLDEQLNYFLEQARIVNLLPLDFELEQLRCLLKVFKSNVLALQSY
TPQVYPNKILYFQASDEVSNEFSNPTYIWGGLSGKPIEIITIPSNHYTIITKPHIQIILE
YLNIFMNQI
>A0A6B9BB88|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium avium subsp. avium|TrEMBL
MLSHHLPDGRIPVLLSSHDPELIRRDAAAILDYLGRIDSPNATAAIASTLLRLRRPRRHR
AVLRAADAAELAAGLAAIARGEEHELVTHSAKTTPPRIAFVFPGQGNQWQAMGAGAYREL
PAYREAADRCAEEFVVAGFASPLPYLVGEEERSWSRPEIQGAQFTHAVSLAEAWRCCGVL
PDITIGHSLGEVAAAYVAEAISLPDAVALVVARATVVGRLTGRYAMAVLGAGLDAAESLL
AEAPGWVEVSAVNGPSSTVVAGDHDAVAAAVRLAQQRDVFTHQLSVDYPGHTSALRPLRA
SLAELTPRSAFRDGPVRFVGSTRGAELGEGTDFSDYWYENLCGTVRFDLAVQYARACGAD
TFVELSAHPSLLYPLGDIVGDESVVVGSGHRERPVTESLSASIAAVAAADPGCRWADAVP
NADQPPLRGFPNAPMRAVHLWAAPERVTEAASPPAPTVAVEDWQHATLHTVATRPDIGFF
GTDALARSLADAVAAQGDCRVVAPNQAEVLAIVAPRLDEHDATAAIEQIAARPDAGLPDY
PALIGPRCRAVWLLTVGAEQVDRDDTHVSPAQAALAAMHRSVGFEFPDQAFGHLDLERAD
VDAATARAVADVLSGEAAEVALRGGEPPLSHVRSHVRSFRECRETATSRPLDAAALDDVV
ITGGSGAIGLQYARYCLERGARTVTLLSRTGVDPAALRELADGHGAEVRAPQCDITDRAA
LASVAATHAGSGASLLIHTAGIAQARSRADLTGVDVAAVCDAKVRGLALMAEVWPLRPDC
RILACSSVFGTWGGYGHAAYAASNRMLDVLAAQLRADGRDCTAIRWGLWQGAGVVVGNEI
TRTERSGLVAMEPEAAIEASLHRYDGDPLIFDADFDRLQVFFESQGMPMPFSASHSGDGG
AQEDVAVAKPLAEVVRAELAATLHLGDSLSIDPGTSLIDLGVDSLLALDLRKRLRRTVGN
SVPVARMLGGITVNELIDALRADSPGGPTPPPIERTGAATGAHHSTLAMLERLDS
>F1T734|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
MINENLLKILKKVKNSEISIEDGTQELQNIKNNHSEVLFYQNYSILANQIVQKDIKNEYI
IVLADDVEHINVIEGLNLDNTSSENQLLWISRGNSFKQDFNSIEMDLNNEAHFEQLSNYV
YSSYDNRKIRIIYMIGEHKFPTGNDWEYQVNSTGITALLFAKSFAYRFNKSGVRFQIFST
ERASEITVFQEAVVALGRSIEKEVPAFITQVVIINPQEVSGLGAVISKELHSEIDTRFIY
YKSDKRMTYNISEMALEAPKNYHEFPEGVYVILGGLGAIGKAVTAEIAKLSNTKIILVGR
RKISDEIETYIEALRHGTNEITYISADISNYIDIKRLFHEVGSKFEKIDYVFHCAGILED
CRLPNKSVESFKRVISSKINGALAIIDMKRTYNFKKVLFFSSTSGVFGNEGQLDYAYANM
LINSLCTKQADPDIISISWPFWDTEGMKMPKEYKEKIFSAYGFRPMPTRVGIDIVKHTLA
DNSKSLIVLYGDRQKLENFSRNTNTDKYIEAKDSSANTVPKEKMSANDNNDGLLDNVIIW
ITEIISKVTGIDTDSLTPKKSIQNLGIDSVMTTEINIEFEKVFDNISKTLLFEYRCIKEI
AEHFIQNYYDACKNKIIIEKSPEKIVEAVHNEEIEVTVKDEIHEGDSGAFEIAIIGIAGK
YPKAESLDVFWENLKAGMDCIDVIPKSRWDYMNYCDENADEWWKSPEKWGGFIEGADEFD
SLVFNIAPAEAKAMDPHQRVYAQTVWHALEDAGYNKKRLEKYKVGVYTGAMWSNYQLYGI
EDAYNGKMEGYDSSLASISNRISYIFNLHGPSITLDTMCSSSLTALQLAYQSIQNHDIDM
AVVGGVNLTLHPYKYIQLKKGNFLSKDGRCRSFGEGGSGYVPGEGAGSFIVKRLDRALAD
KDKIYGIIKGVSINHGGKAQGYFVPNPIEQANVINAALENAGVDKKSISYIEAHGTGTSL
GDPIEIAGLRKVFEKDNNQKQSISIGSVKSNIGHLEAAAGMASLTKVLLQMKYKMLVPSI
HAEKLNPNVDMKTTPFKVQTQLEPWSGDDNNILRAGISSFGAGGANAHVILEGYDNSYKD
IIETKEKKIFVLSVKNEKALLRYIDLYRNFLLKTPQATEEYEFDTRLAYTTQIGRNHMNV
RVAIVFENTKQLIQCLEDITLGNEKSLNVFINNVSNDKLDVKSLDIETLKYDLSANAVEI
AQAWVDGYEVEWEKFYSEKMAIVNLPLYPFEKIKHWAPLGESRIYKMKNEAESICIDLYK
KQWSKSEASSSTTEIYNANIVFLIKKEQSFLKSAAIKAMNLDSAEFIEMDDASTVCEASL
ERKVKQKNKTVVIDLSDLQTGSKEIFKIPHSKFNLYKHLIKKTRQAGLDILHCTQGVNEG
ITQNGVLTAGLMKSLGAEYPWIQSKTIDFTIDYTMDSILNCLKNEITFDGNGEVFYKAGI
RNTTGYQQLEFNWKSDNAFKVEKDKCYIITGGTRGIGAKIASRLAELGAKKLVLLGRSDM
NTPEKKELLKDLESHGTEVLVYSQGLHNKTALEDFFKQVYQQFGEAHIMFHCAGRYSTEN
AAFIHKEEREIEDVLEPKVIGLLNMLEATKVLQVEKTVLFSSISSICPWLSKGVSDYTMA
NNYLNGMPEYGKNITDSQVLSVVWQSWSDVGFMVSEPKIGKENGLIPINCKEGIDILFNI
LQKEVSGVVVPVKHNEVFEIEKLAVLSKNKPASDFTQQTVDNKRLSSEVNVITEIITQVI
SDVLLININEISLDEAFENYGMDSIFLGEVIKKLEEKLHTAIDPVLFFECNTIRKISTAL
TGIVNISLPKKESIEIKPCGVNENPRFAVIGADCRFPDADNCIEFWNNLMEEKCSVKEIP
KERFDMEPFYSPTPEVNKSIGKWAAMVKDIEYFDPKAFEIPETEAATMDPLIRIQLETSV
NALRNAGYDKADVKGKNIGVFIGSRVGDFHSLMPKEQKAKITGLGQNFIAAYTSHYLDLK
GPSMVIDTACSSSMVALSEACKNIHFGECEQAIIGGVDLILCENTLVLLSDALSPTGVCS
AFDEKANGFVPGEGCGTIVIKKLEQAIADGDNILAVVESVAINNDGHTMGITTPNYNMQM
DVIKRAIERTDIAPEYISYIEAHGTGTFIGDPIELKALTSVFREYTDKKNYCGIGSVKTN
IGHCLSAAGMASIIKVVLCLQNKKLPKTLNCDKPNSRFNFEQSPFFPCTKNKEWEGINGR
RIAGISSFGFGGTNAHVILSEYTGHHEVIRQPLPPLALNKKYYWFDKKEPTSTTIINTNS
EANMFGLKKMF
>A0A1E3H071|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Methylobrevis pamukkalensis|TrEMBL
MTLTETDIAIVGYACRLPGASDPDAFWSLLSRGECVISEVQPDRWSKNRFGHPDRGVIGR
SYTWAAGQIDDIWGFDPTFFGISPREAEQMDPQQRLLLQVVWEAFEHSGIAPSSIAGREV
GVYVGASGMDYSHMLVVDPASGDTQSMTGNTLSIVSNRISYIFDLKGPSFTVDTACSSSM
VAMHEALEAIRAGRIDTAVVAGVNVLLSPFAFIGFSRASMLSPTGLCRAFDAAGDGYVRS
EGAVAIVLRRADVAEAAGNTLRSLVVGSGINSDGRTAGLSLPSGEQQAALLAQVYERYGL
DPDDLAYVEAHGTGTRAGDPIEASALGGILGRRRALPLPIGSVKTNIGHLESASGLAGLL
KAQMALEHGVLPPSLHFRNPNPDIDFAGLNIEVVDETRTLPAGDGPRLVGINSFGFGGAN
AHVVLREAPGTRAMSRPAAVGAAPVVQPPLVLSAQSRDALVAMAARYRDVIAAGDDLAAA
KIASAAAWRRDRLDHRLVVVGTGRDQILAGLDDVIAGGRKTPVARTIQRTAPVAFLYAGN
GSQWAGMGRAAYQTDTNFRLAFEAVNRRFMRVAGWSLITTLFSEDLEADIERTEVAQPLL
FAVQVALTEALQKRGLRPDAVAGHSVGEVAAAWAAGALTLEQAVFLIHVRSTQQEVTRHL
GGMAALLVSADQAREALAEPEFAGLELAGDNSPRSVTLSGRYDVIDAFAKYARKKRWALR
KLKLDYPFHCALIEPIHHEIIRALSGLMPVAGEKTFVSTVTGDVIDTTELDADYWWRNVR
QPVLFNTAVERLAGLGMRVFVEIAPRPVLQNYVGDTLAAVDHAGAILPSFGEDDAIGRDV
VGEIVAAALANGAVIDDAAFFGAPVAGEVELPLYPWQNQQYRLNLTVEAHDVFGRDFDHP
LLGSQPRAEGGPFIGNIDTSMLPWLMDHKVEESVVFPAAGFVEMALAAARHTFGEGPVEV
LDLDILRPMLLDESVLRETRVDVDRDGHVIEISSRRRLSQDEWSLHVRARLARSPAPEAP
RLALPDPLPAVSLDHDALYTLTKSFGLNYGPAFRRAVCVRPLGENAVCLELSDAEQAVLG
DADYALHPTLLDATFHGLFHLIAETGDGRRDGSFLPVRIGETRVFSFGRTPAAAIIEVTK
ASVRSIEARFTLVDAEGVTIARLDGVRFKAVQLSRADDPDEFAFRLAFVRRADGDETGST
APGRNPLAERAAALGLVRDMPEELGEAPLLIDAAARAVAFDVLRGLATADAIDPGARVAE
GRLHASALPLVHRLLDAAVEDGAATETPTGWRLETETPYPDLGTLVATLLADHPRRIAEV
GALTRVATLLPRRLREGLAAGLDETLPASLADHLETASDAARPLIDAIGTLADDLAAAWP
RTRPLRILVTGAGAAEIALRLAARDARITSLAVTDVDSSRLERLRFAIDGAERIDVVAFA
DLGAAGPFEVILSCGGLGRAGDDGVAAKLRAVLAGGGSIVAAEPAPTFFADLVHGMSAAW
WRAGFDRPTGRLRTASAWSQTLEAAGFDGIVSRGLVTPQVDAQLLVARNPTMLPGTALPE
AKTDPVLVVAAGRAAATRSLADALCAVTAAAGRAVHLALADVQEDGVATLEPIDGGSDRD
RLHGVLSSGTAKDLVLLPDLGATDPLSAVADATMVVHAILNGAMKPPARLWLVAPGGSGA
NAAARPHDPVAAALWGLGRVLMNEYPDIETRLVDFASAFAPSEAPAGLPR
>F1T735|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
MFKEFGYSLIIDENNLVVRDHIVHGAKVMPGIVLLDLCIKVLLSENIDYKTIEFRNILFK
TPIELLTSNKRELVISLKNIGQKSFITGKSHIADIEQNNTDEMVEHFECEICQVSPTARE
QINISEQLTKSAEYIQDMDEAYKFVRNVGITHKSFMKAEGKVYCFKDKIITHSKLSQEAN
QYKDGFFHQPSIMDSSTIIPYLCIRDNKISEVENKAFIPIHIEKFRAFKPLYSEAYVYIE
NKDVSVANSGDVTSASWKIFDEQGQLAADIERLSSKQIREVGMATKQVTSTQEINSDEQE
APKLGLEKLSLTENSIEKYIIKKIEDLKKIIIQESDLEKGFYELGLDSRDLISVVKNIEN
QINIQLYPTIMFEYSNIKELSEYLKGQFSEQFNIYLTQNQTPPPNQKREKVKVTADKLNN
QNDENVIFEAYWKEDIEEKEQSGEYGPSLTIILTNDSEVYKKAKEQLRNVIHICSNKMCK
EIDDNNSYCINPLNKEEIEQVFSKTVPENANVNVVNMFDFDCLNELVSNYSEQVVYIFNA
LFCQALIKFADANSKIRIVNIGFHDNANNCYTSALTGFYKCLAAEKTRITSSIITLEYDK
KLYSSQLVWKLIINEFSKQKLPVNEIKYRDYVRHVKELCLTEYKESTNVLFKDNGTYIIT
GGMGAIGKSLVNAIYKQYACNIILLGRSSITNEMDIWLQRVNSGKAKVVYHSADICNKQA
VDKEVRWTLAEHGKINGIIHAAGCLQDAIIMSKKFSAEAEEPAITTKVAGINNLDSAIGE
EKIDYMILFSSISAVFGNLGQSNYAYGNGYMDNFSSMRNELAHKKLRYGRTLSINWPLWE
LDGMDVGYDYSHIYNATGIQKMNHNRGIDLLLCANYDNSSQLIILNGVKAKINSFMTKHY
KITDKNHVQQRKSMSEAYSQSKNIAIIGIGGQFPMAGNVMELWENLKSGKDCIQTVPEER
WTREDIKAIIGEDSTLDVSNYGGFLKEIDRFDSRLFHITPSEAKMMDPQERLFLSIVWTT
LEDAGYSMKQLVNKDIGVYVGTMWGQYQMFSTLLDNQPALPSSIFASIANRVSYYFNWHG
PSLSIDTMCSSAMTAVKMACDSINNNEAEMAIAGGVNLSIHPAKYIVLAQNNFTSKDGRC
RSFGENGSGYVPGEGVGALLLKKLDKAVENGDHIYGVIKACEINHGGRTGGYSVPSVQYQ
SKVIERAIKASKVLPSDISYIEAHGTGTALGDPIEIRALQSVFDKYTNEKQFCSIGSIKS
NIGHLEAAAGIAGIIKVLLQMKYKKIVPSLHSKKINPNIDFKGTAFYCQQEYENWNSDGL
RAAAISAFGAGGSNANIIIQEYEPSRSKVRGVSPKLFVFSAYNQDILLNYVKKHIDFLSQ
YSSYNDIPTENIDLADLDNIIIDFFGFNNNELLCTYLLDELNFDLYKMVKLEELLKRNRL
KSPSVEQFAVCKSISELRQLLKTKNDCNETVCEVKAKSELSQEEEAEFLDSYEYTLQTGR
VHMKKRLAVIASTTEELLVYLKMFLQNQNHENIILKQSKGEESTLLSMFKGNAGVNFIKA
LIDSGDLNNIGQLWVEGIDLEWEKLSNTKGRRRMSLPTYPFSGEQIPSAQLAISHNKGIY
EEKENSDELNLYEIIKKVESGTMTVNSAIGFLERGN
>F1TIW5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
GQVLYLQADVCDQARMKEGLSQAKERFGEIRGVVHTAGLAGGGSILDKDISSFEEVLGPK
IKGTIILDELLCREPLDFICYFSSSAAILGDFGSCDYAVGNRFLMAYGHYRNNQQPGKTV
VINWPLWKEGGMGSKEGDNAEMYLKSSGQRFLETEEGIFMFDRLLAQNDIQHLVLAGQPS
RVHRFLGLAGNQSPAQTPDIYKPSGKGRRTEMKGLSLEQCLEWDLKELAGNVLKISRDKL
DKEENFADFGFDSFSLAEFATILTGHYGIEITPAVFFGHSTIERLTQYFFTEHQQAIQDF
YREDAAVQDVLQREPQAAASSRQRAGRFRFAAGSTPQGVPEPIAVIGMSGRFPGADTVEG
LWNNLKDGRECITEIPASRWDWQKYYGDPHQEDGKTNSRWGGFISNADQFDSQFFEISPR
EAQVMDPRQRLLLQEAWKALEDAGYGAKQIKTNRIGMFVGVEQGDYQLLVKEKASVTSNN
NAILAARLAYFLNLSGPVMAIDTACSSGLVAAHQACLSLRGHECDTAIAAGINLMLTPQA
YIGMSQAGMLSADGKCFAFDKRANGLVPGEAVAAVVLKRLSRAEADGDPIYAVIQGNAVN
YDGRTNGITAPSGVAQTSLLKAVYDQFKVNPEEIEYIVTHGTGTRLGDPVEINALYDAFK
GYTSKQGYCALTSTKTNFGHTFAASGLLSLISLVEALRHETIPASLHCEQENDYINWKES
PFYVNKAAKPWPKRDGKVRTGAVSAFGMSGTNVHMVVRSYSGKDTGSFQEQPPYYLLVLS
AKTEDALQEKIQDMITVLQNKGQDLLRISYTGLEGRQHFNHRCAIVIQDHDDAIYVWKQA
GSRERLPNLFKGKVPQDFKGQNVVQQYAQDMLKQSKSLQCDRSKYQEMLFALADFYCQGY
EIDWSGLFGGKRIKRISLPTYPFAKERYWVRETETTPNASPPITGYIHPLLHQNTSDFSE
QRFTSTFTGQEFLLADHVVQGQHLLPGVAYLEMARAAVEQVTGALEGQKIQISLKNIVWM
HPITVRHNPARVHIGLYPEENGEITYVIYSQHDEADTERVIHSQGVAMLGPVGEGQRMDL
QAIKSECDRGVLSSAQCYEAFSLMGFDYGPGYQGLEKVYLGSDKVLAKISLPSSVCGTGD
QFVMHPSLMDSALQASIGLLLAPDSRIQSGGDVPSTMSLPFALQEMEIFRGCSSTMWVLL
RYSNGTKAGDKVQKLDIDLCDDQGRVCIRMKGFSTRMRGGDSWQSETIMMTPVWDVIAVE
GGRDFSAKAQRVVIVGGREDSRSAVLQYYPDAQVLEIKPRDTIEIISKKLLARGAIDHII
WIAPYKPVTTISDDILITDQNEGVLQVFRIIKALLGLGYADNDLSWSLITVQVQSVHKNE
TINPTHASLHGLIGSMAKEYPHWKVRLIDLNAESDWPIDDILNLPADPEGDILAYRGKEW
YRQQLIQLHIPAPERTLYRPEGVYVVIGGAGGIGEVWTEYMIRTYQAHVIWIGRREKDAT
IQAKLDRLASLGPSPQYIKADATDQKALQQAYEKIKKLYPQIHGVVHSAIVLLDKSLANM
DEERFNNALSAKVNVSVRMAQVFQKEPLDFVLFFSGLIAFTKSPGQSNYASGCAFEDAFA
SRLSQEWPCVVKVMNWGYWGSVGVVAAKAYQDRMAQVGVGSIEPPEAMEALEVLLAGTMD
QIALVKTTKPNFLNRQ
>F1T738|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
MEQAYLDQIVRDLLNKDNGDIDVLNGFIDFENDLSGNASQNSKTVQFIKDTLITDKKKLV
QLYNNKEISGDTLVQSLKLIQKNDNCSLAVYTPKWLKKDIEKEKKSSLGTIICFSLQQQL
GEALAGQSGDNVYLINCEMDISSESCERITEKVRQYGDSILSVVIDNSNLELQNSSEQIS
QALEGLIEQVYILIKVLSKLKNVQEINIQYIYSTKEDKKKVLLNSISGLFKNYCVENSKV
LCKSIDIGDISDINEKASLIKQEFHSMGDYLEVAYCNGFREVNVIERVLPDYTTANIVKQ
RGCYIIVGGLGRIGQSLASHLVSCGASNIVLVGRRAMTNEEEAMLKSFNGRDELVTYKKC
NILNASQVSKLLNSLNKQYGIINGIYHTAGIIKDSLAINKQQENVIKVLEPKIKGTINII
NAAKKLDVDFVMLFSSLASVTGNMGQSDYGFANAFLDNYAELEAQNGVGTQVYSVNWPLW
KDGGMQVDDDRVQLMINATGMAPLLTSTALLVIDTIIENKIPRSIILYGHNNRIEKMLAP
LCDKQEAIEETLLPLNNEEDDAITEDAYSVQDNCDGELYDIVSKYISKALTEVAGIDVET
LSEDCSFDEFGLDSIMIERLTNYFESDSLSLPSTILYEKKTNRDLSNYIIENHRSFIDKK
FGKQSNKQNEYQRIRNYLENTFCRVTGIDKNSLSDDTSFTEVGLDSILVEKLHTCFEEDG
ISLPKTIMYEKNNLSELTNYMIENQINSVKSTTNVKQTQKKAEPIKIKKEELLSKVLTPN
GDIAIIGVDLRVSGAKDVREFWNNIINKKVSITEVPKTKWDHDKIYSSNINDTVYGKSYC
KYGAFLEDADCFDAMFFNISPKEAEIMDPQERILLESVWRLLEDAGYTRGELKRKYRKHS
QPGVGVFIGATNHSYALSAVSEWNKGNYTIPSSWQWAFANRISHVYDFSGPSLPVDTGCS
SSMTALHLACKSIINGESSIAVVGGVNLYSHPTSYIGASKLRLLSSNNEYAFLGEDSDGF
IPGEGVATILIKPLEKAQEDDDKIYGVIKGTAINHSGQTITFFAPSSELQEELIEKVAGE
AKVGLNTIDYIEMGTTGSTIGDPIEFRAINSAFKKNNIQKGSCAIGSVKPYIGHLESASG
LIAVIKSLLQFKHNKIVPTLLADKINPEIDIKNSPFFITSEAKDFEKGDTARRVLINSIS
AGGSYASAIIEEYSADTLHNYTEGPYIINISAKSEISLKLYLVEFSNWLDKNPEASLYDT
SMMLMLKRECFSSKVSFVCNSISELKEQIKEYCQGKIIDGVYDNKELKLNNFDKNLYSGK
AGKAFINAIYQEKDIKKLAYLWTIGAYINWNELYGENSQFKKVDLPCYEFEKERYWITDK
TENIVSIQDNAGKISSLIDANISTLGNVCFSKLFTGEEFFIKDHLGILPAVAYIEMIYQG
IMASSKGHNLIGIKNLVLMRPFVVRAEKRVLKVRFMLQRETVSAQVFSDVPCEIVYAQCN
IVLGKKTGFPDKQLKVADCISSMTGGKHEAEEYYNHLERLNSCFGYRFKGIKAFFFRDKE
AFAEAGIVDVLDATRKDFNYHPTLLDAGFQSVVALAYKMGANAETIYMPFVTENIEFFKK
GTAIKYVHVIAKAGKTQNPSEWKYTVEYYSEACKMLARISNYTILAVNGDVSTKALPENV
CSIENKSDDQENIEFIQENSITETIINVCAQTLKLRKKIDPDTSLLEYGFDSITFTELSN
AINEKLNIDTNPVLFFERNTVNNIVEHILEKYTHVKEAYKTTCHSSVSSQAYPDYDFTRV
FTNAESNYQVKEYSDKYAIIGMSGAFPGSSDIEEFWDNISQGRDLITDIPSDRWDWREYD
GDSEYGAYNIYTHSGGFIENVDCFDAKFFKISPLDAAIMDPQQRLVLEHTWKAMEDAGYS
SKDLKGTDTSIFIGISNADYGELLVQRKIPTVLTHSMVTNRISFVLETTGKSEPCDSACS
SSLLAIHRAIETLKNGESKMAFAGGVNLILSPNTYVYECLSKALSPTGKCKTFDEAADGY
ARGEGVGVILIKRLQDALADGDSIYATICGSAVQHGGKSTGLTVPNAEAQASVIKKAYDN
AGISMSTVTYIEAHGTGTKLGDPIEIDGLKKAFAEASSGSEHIVKTKACALSSVKTNIGH
LEAASGIASVIKAVKSLQNKKIAPTINFKTLNPYIDLKDSPFYVNRELTEYAPYYNADDG
ECLPRRAGVSAFGIGGVNAHVVLEEHENPTTELLESKSKDNFIFTISAHNADRLKVYLKL
VSDNIGKVRTGVDTQDNVLLQRLCYTFQVGRDRFNCRCAINITSLSELVEMIDKVITEQA
DERYILCENIAKYSSWCKEKCEKGSESELTNHMIETGQIKDLTQMWCYGIDVDWNQLYSL
EKPRKIHAPTYPFKKERYWIPEYYSLSSTEADISQEASGTQQTIAFSAKDAFLRDHIVDG
KMILPGAVYSEIIMKAACTTEEKQFNCIQDMFWLGNFEAGSKPIELAVSIDKKDSISTVS
ITSNKLLAKGTVLNNDAIFKEPDIAALIDSCEKPFSRDYVYKQFEAANMMFGETFQTINA
MWCANDYSVVQYVIENDDKSEEYALNPRILDAAFQSVVGNISAGFNSGQIRVPFYMEKLT
IVNRPMERGFILAMRKKISSKSDSYDIFIMDLYGNINVVIQEYVVQKIINNK
>B3E4P7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Trichlorobacter lovleyi (strain ATCC BAA-1151 / DSM 17278 / SZ)|TrEMBL
MKQSEQDRTLTTAGAPLAIIGIGCLFPKSEDKAAYWATIREGVDAITEIPASHWRVDDLY
DPNPKTPDKTYGKRGGFLSEVPFNPMEYNIPPNSLEAIDTSQLLGLVAAGQALQDAGYGS
DKQFDRSKVSVILGVTGALEMVIPLGARLGHPRWREALKDAGVAPDVAEDVVQRISDSYV
GWQENSFPGLLGNVVAGRISKQYDLGGTNCVVDAACASSFSALHLAGMELTTGAADMVVT
GGVDTFNDIFMYTCFSKTPALSATGNAKPFDVSADGTILGEGLGLVVLKRLADAERDGDK
IYAVVRGIGSSSDGKGEAIYTPSASGQQKAILNACANAGVTLDSIGLLEAHGTGTKVGDA
VEVSAAREIFGEADQPWCAISSVKSQIGHAKAAAGSAGLIKAALALHHRVIPPTIKVTKP
QDEVTAGRTPFYITTRKRPWITRNNTPRRAGVSAFGFGGSNFHTILEEYRPLQEAAEWDG
SVQVLTFSSADAAGLTAQLANISTDIAWNDLRGKAASLRAGFDPKAACRLALTVERSSNL
GTLLHTAQTMLAKQPGANWTTPDGICYASGAAVAQPGLLFPGQGAQYVGMLRDLACAFPQ
LLDSLEQAETTTPGLTDLIYPADRFEQGAAEQQEAELRATQIAQPAIGAVSLGALRLLET
FGLKAAAAAGHSYGELTALCAAGLLDETSFHSLSRLRGSLMAAGSGGKGSMLAVSAPLAA
VEQMLAEEKINLVIANRNAPTQAVLSGATDQIKLAEAACKSRTLTCKQLPVAAAFHSPLV
ADAAAPFLAGLADIRWGSGSMPVYANSSAAPYPADMAAAKELLAGQLARPVEFVAQIEAM
YAAGIRCFVEVGPGARLSGLVKAILGDKEHSCVALDSSNGKRNGLVDLGRCLAQLSVLGL
EINLQLWDEGYHAPAAPAKKPLLVVPLCGANYVKPKPKRPAVAPKPVSAAQPAASSIPVA
PAPITVQATAPTASRDALAESLRVTREGMAVLQRMQEETAQLHRRFLEGQETASRTIQTL
LSQQQQVLQGGMATIPAMPLAPVTTAAPVMPAPVVQPQPVQAQVIAQPAPVAAQPVSNAV
TETLLTVVSEKTGYPIEMLELSMSMDADLGIDSIKRVEILSALQERLPSAPVIGPDQLGV
LNTLGQIAEYLGAGAAVAPPASTPVQQVSSVITETMLAVVSEKTGYPIEMLELSMSMDAD
LGIDSIKRVEILSALQERLPSAPVIGPDQLGVLNTLGQIAEYLGAGAAVVAPAAVSGSQP
ADSAITETMLSVVSEKTGYPIEMLELTMSMDADLGIDSIKRVEILSCLQERLPSAPVIGP
DQLGVLNTLGQIADYLGAGAAPTAAVVTAVSATQPAASNITETMLAVVSDKTGYPVEMLE
LTMSMDADLGIDSIKRVEILSCLQERLPTAPVIGPDQLGVLNTLGQIADYLSAGTAATAP
APAATPVQPTAAAAPSQTVLNRSRIQAMPVAGGSDTISLAQNGVIVVTDDGSRFSAELCS
CLTSQGHGVILTKVLDILELLPMDQVAGLVLVAPADGTDDAFLKNGFQLLKQMAPGLKRA
SREGGALFATVSRLDGAFGSTEGSELIDPLSGGLAGLSKTARHEWPEVACKAIDLGIFPD
RSAAAQAVARELFLNGPIEVGLSAEQRISLPLQDLPELATAATPSVQPGELVVITGGGRG
VTAAAAVAMAKAWQPLLVLLGRSPLPEQEPDWLQGMTDEAAIKRAILTHATEKLHPREIE
ERYQATIAGRELRETMAQIQAVGGRSLYCSVDIRDSQAVADLLADLRKEHGQIRGLVHGA
GVLADRLIVDKTREQFNQVYSTKVAGLRSLLDATRADDLRFIALFGSTTGRLGRSGQVDY
AVANEVLNKLAQAEARRRVNCRSLCLNWGPWDGGMVTPALKKVFAAEGIGLIPLEAGADL
LVKEIAAATGPVEVTVLAGVKGASLSIDAPKPAAPLKEALRLTLNVDDFPFISSHVIDNK
AVLPMAMIVEWLAHAALHGNPGFRFHGFNDLRICKGVIIDRSTPCTLQLMAGKAKRQDAF
YTVPVELVSSLGEGRSLLHARAEIILANKLPEGIRTIKELPSHPYNQSSAVYDQPYLFHG
PDLHGIEQVIGCSDKGIAALVKAAPQPGNWIKQPLRSNWLTDPLVVDSAFQMMILWSFEQ
FGAGSLPSFAGRYRQFHETFPRDGAQVVIRVTSQQSHSAVADVEFLERANGKLIARLEGY
ECVIDASLQQAFQRNQLPQAGQSAALVAA
>A0A3N6D2A5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI91-18|TrEMBL
MADRDAVTALLADVPADRPLTAVVHTAGVLDDGVIDGLTPERFATVLAPKADAALTLHEL
TRDLDLSAFVLFSGVAGTLGDAGQGNYAAANSYLDALAEQRHADGLPATSVAWGRWGDSG
LAAGGAIGERLDRGGVPAMAPRAAIRALQQALDHAEPAVAVADIQWERFTPGYTAVRPSP
FLVDLPEVRALVRAAAAAGDAAGADGDGSPAEALRRRLSVMPQAEQALAVLDLVRSHAAT
ALGHPTTDEVGAGRAFKELGFDSLIALELRNRLNAATGLKLPATLVFDHPTPAVLADFLR
GEIVQDGSAAAAPGIAELEKLESALSVIDPDGETRSDIASRLQALLAKWGEPQAHSSGGA
VAEKLQEATADELFDFIENELGI
>A0A5P9Q1N2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Amycolatopsis sp. YIM 10|TrEMBL
MVFDLVEPIAGTGALLCCGDLRAETHPWLAGKPLPRELLAELLSLAGAEVGCAHVRELRV
EAELLLPARFQVRVGALENGMRAVHLYTRRGEDWTEHATGIVEPAVVAETTDDGWHPLPP
APRADGPEPQVVPFTTTEHARELARGGERLVFADEHEATAVVLPEVLGSATPPLIVRAGV
AYALDGNENAVDEPIAVIGVSGRFPGEIGPVPEDRGWDVSPRGAFLRAPGDFDAAFFGMS
GEQALVVDPQHRLLLETAWEAFENAGIDPERMRGEKVGVFTGVHGRHYESLVWAASMDAR
PMPAAVRVAQAFGLAGPAVETGEACRTAVESLRRGESAMALAGWASVLATPDAVDSVDAD
PAEGAGVLLLQRLSEAERLGHPVLAIVPERPGPVAELIESVRRTVRPEPAEPIADLPMAW
PLSAKSEAALRARATQLLSCLDTDAPADIGLSLAERTEFTHRAVVIGENPDEFRAALTAL
ADGRTAPNLVLGSAAETTAPVLVFPGGELDWSSNELLEHPVFADRIADCERALAAHVDWS
LTELLHNELVPDRVDVVLPVRWAVQVAVAALWESFGVRPSAVLGHGDGEIAAAVVCGALS
IEDGAKVAALRARALRGIVGRGGAVSVALPEHEVVDRIGFWPGRVGVAAIDAPDSVLVTG
DATALDELMYRFKADRIRVRRLPVGHAAHSSHVEEIEQLVKDLLAGITPVPAAVPFFSTV
TGDWFDTTELTADYWYWNLRQPVLFAHALKALADQGCVFAEAGEPGGPRQFLAEVARAHL
RGVAVDWRACFPGARRVALPTYPFQRERYWIDLTHSGSPASAARSADHTAA
>A0A5P9Q1J2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Amycolatopsis sp. YIM 10|TrEMBL
MSDRIDNALDCWRHRLDWRRVSGTPALSGRWAIVVADLDDGDRFAAVLRRYGAEPILIPA
GDRNAMADCFRIFRELSGVISLLALAESPEKDLPPGVASTVYLMQALGDAGQSVPLWCVT
RGAMTDGGDPVQALLWGLGRAAVLENPHRWGGIIDLPADFDAVTARLFATALSHRGGDNR
FAIQNGELRAARTVREPGHDWVPRGTVLITGGTGALGTRVARWAAEQGAQHLVLVSRRGP
AATEAAELRKLLAGTRVTMAAADVTDEASLARVKREFGPIDAVVHTAGHDAVGPLPELRP
ADLRTRVVGARNLDRVFAATELDAFVLMSTLDGVQGRTGQGAAAATSAYLAALAERRRAR
GGRAHALAYDCRGTDDLRIFVFPDRLDQPGLAAELCDRSPDFAATYAECEQRLAKYTDPR
HGRDWATMVALAAMWQAHGVRPARVLGHGAGEIAAAVVGGSLTLEEGAKAIAVRSQEMVA
VSLPESEVADRIARWQGRIGVLAVDGPESVVVSGDPAAIDELTFRFRAGRITVRRLVRAS
AGNAEAFERNLAAYRRHGYRLIEISGPPVPARPSRSLEVG
>A0A2K8P9Y8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces lavendulae subsp. lavendulae|TrEMBL
MAGANEEKLLENLKWMTTELRRSRRRLQEVEQDAREPLAIVAMSCRFPGGVRSPEDLWRL
VSEGGDAITGFPDDRGWDIASLADPDPDRKGTFYNTGGGFLTDATRFDPAFFGISPREAL
AMDPQQRQILETSWEVFERAGIDPATVRGSRTGVYIGAGAMGYGADLREVPEGLEGLLLT
GGATSVLSGRVSYVLGLEGPAATIDTACSSSLVALHLAGQALRQRECSLALVGGVCVMPT
PDVFVEFSRQRGLAADGRCKSFAAAADGTGWSEGVGVLLVERLSDAQRNGHPVLAVVRGS
AVNQDGASNGLTAPNGPAQQRVIRQALENARLSAAEVDAVEAHGTGTRLGDPIEAQALLA
TYGQDRPEDRPLRLGSLKSNLGHTQAAAGVAGIIKTVMAIRHGVLPQTLHVDEPTPDVDW
SAGAVSLLTEAMPWPETGAPRRAAVSAFGVSGTNAHTIIEQAPEADTAEQPPHGAQPGGA
SGTGTGSAAPVTASATASVRPTLLPWTLSGRSAAALRAQAARLVAARTADAAAGSALDLG
LSLATTRAALEHRAVLIGRTGDDLDSALAALAAGEEAAGLVTDTAAEGRTAFLFTGQGSQ
RPGMGRELYASQPVFAAALDALCARLDIRLELPLKEILFGSDAALLDRTEYTQPALFAVE
VALFRLLESWGLKPDFVSGHSIGEIAAAHVAGVLSLDDACTLVAARARLMQELPASGVMI
AVQASEDEVLPLLTDRVSIAAVNGPASVVIAGDEDAATAIVEAFPDRKSKRLTVSHAFHS
PHMDGMLADFRRVAEGLTYESPRIPVVSNLTGALVTDEMGSAEFWVRHVREAVRFLDGVR
ALEAAGVTTYVEIGPEGVLTALAQDCVSGEGAAFVPALRAGRPEPETVLAALARVHAHGG
TVDWAAYFAGTGARTVDLPTYAFQHERYWLEPGADTAGDVSVAGLDPAGHPLLGAAVTLA
GSDRLLCTGRLSVRGHAWLADHTVAGAAVLPGAAFVELAVRAGDQADCGHIEELVLDAPL
ALPADGGVRIQVLVEDADERGRRTFTVSAERAGGTAEDSGWTRHAHGVLAPAAAAGSAGP
AASFDLAEWPPAGADAVDLSRLYDADTAGGLRRGPVRGPLFQAVEAAWKRDGEYFAQVRL
PEGAAQEAGFGLHPILLDTAAHLATVLADTDADADTDTDTAPDGGNGVGPGSVWSDVALH
AVGAGALRVRVRPAGEGAFALDLADDLGDPVATIGRLAPRPHTPAATDATDPVPAVVREA
LFRLDWTPLAVPATATAPAGGWAVLGDTGFGPAVRYAGLAELGEAVDAGTPVPAYVLAPF
PRQADGPDALSGAAQRALALVRAWLADSRFETARLVLVTSGAVAGPGEGAEDLPHAAVRG
LLRSAETENPGRFVLADIRDLGEAAGSAEAAGSAGSADLAVLAAALDSGEPELLLRDGAV
HVPRLRRAATAATVTADATAGAVIDPDGTALITGGSGTLAGIVARHLAGTHGVRNLLLLS
RRGADAPGTAERTAELDALGARVTWAACDAADRDALATVLAAIPAEHPLTTVVHTAGVLD
DGVIGSLTPERLDTVLRPKALAAHHLHELTRDLPVTAFVLYSAIAGTLGAAGQSNYACAN
AYLDALAELRHHQGLPATSLAWGLWAEAGGMIGTLDEAQLRRMEQHGMGALTAADGMALL
DAALASGRSVLVPARLNLPALRAAAAPGPVAPVFRELLGRAGRRTARTRDDAGTSLTDRL
TSLTRSERDRVLLDLVRAQVASVLGHASAERVEPGKAFKDLGFDSLTAVELRNRLGAATG
LRLATTLVFDHPSPVALARLLYCELLGDEETGSGAEGVRSAEAAEDDPIAIVAMSCRYPG
GVRNPEELWRLVAAGGDAIGGLPGNRGWDTAELYAGQGGDGRAFEGGFLYDADSFDAEFF
GISPREALAMDPQQRLLLEASWEAIEGAGIDPSSLRGSRAGVFVGASYTGYDAQLERSAD
ADGVLGHVMTGNAGSVMSGRVSYALGLEGPAVTVDTACSSSLVALHWAIQALRNGECTLA
LAGGVTVMSTPGTFSEFSHQGGLSPDGRCKAFAAGADGTGWGEGVGMLLVERLSDARRNG
HPVLAVIRGSAVNQDGASNGLTAPNGPSQQRVIRAALANAGLSAAEVDVVEAHGTGTRLG
DPIEAQALLATYGQERAEGQPLLLGSIKSNIGHTQAAAGVAGVIKMVLAMRHGVLPQTLH
VDAPTPHVDWTAGEVTLLTEPTPWPQTRRARRAAVSSFGISGTNAHTIIEAAPDAPEDPT
PTTPATGPVPYVLSARNPSALRDQAARLLPVAEAGDCALVDLAHSLATGRAGLEHRAAFA
AADREGVLRALAALAADEPAPGLFRGTVSGGGLAFLFTGQGSQRPGMAHGLYETQPVFAT
ALDGVCARFSLELPLKDVLFGSDAEVLDRTEYAQPALFAVEVALFRLLESWGVRPDFVSG
HSVGEIAAAHVAGVFSLEDACTLVAARGRLMQALPAGGVMIAVQASEDEVLPLLTDRVSI
AAVNGPTSVVVAGDEDAAVKVAEAFPDRKTKRLTVSHAFHSPHMDGMLDGFRKVAEGITF
AAPRIPVVSNLTGALVSDEMGSAGFWVRHVREAVRFLDGMRALEAAGVTTYLELGPDGVL
SALAQDCVTEDAATFAPLLRKGRGEAEALAGALAQVHTRGVTVDWTAFYAGSGARRVDLP
TYAFQPVRYWPEPTAPRGVAPAAGAGSEADARFWEVVERADLTAFADEFAVDGEQPFRSV
LPALAAWRRDRQAQAEADALLYRVSWQPFAGQDRGALTGTWLVAVPAAQAEDPWVRALTD
RIGAEGARVLPLPLDVADGDPAVLRTGLDGLLREAATDPGTGAVTGVLSLLALDERPHPE
HPGVPVGLALTAALTSVLTSEPAGPGAELADAPLWCVTREAVAAAPGDTLGGATQAQVWG
LGRVFALEHPDRWGGLLDLPAVCDERVLSRLPAALTAAGDEDQLALRATGTLVRRLVRGT
TAADADGTRTGSGWNPCGTVLITGGTGALGRHVARRLAERGAEHLVLVSRSGARAPGASE
TRTELEALGAAVTLAACDVTDRDALAALVAGLAADGTPVRSVVHAAGISQPPGTGTDLPG
FARVVTAKTAGAVHLDALFDTPDSLDAFVLFSSIAGVWGSGGQAAYAAANTFLDTLAERR
AARGLAATAVAWGPWAEAGMATEGDATEQLTRRGLPPVAPATNLTALDRALAGRDAAVTV
ADVDWARFAPVFAAARPRPLVGDLPEVREALRGETADGATPTGDGTAADAGATLLRRLGE
LSGEDRDSALLDLVREHAAAALGHPSADAVAPDRAFKDLGFDSLTAVELRNRLGAACGLR
LPSSLVFDYPNPQALTRHLLRTLLPEGSGGGAAAAAVADLDSDPLDAELRRTLAAIPMGR
IREAGLLDTLLGLAGSGSDTTAASGPGARAADAGESIDTMDLQDLLDLALDGGGLDDDGP
TGDTTTSNSNF
>G7LK38|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Brenneria sp. EniD312|TrEMBL
MDNLRFSSAPTADAIDASIAQHYPDCEPVAVIGYACHFPESPDGETFWQNLLAGRECSRR
FTREALLVAGLDAAIIDDPHYVNIGTVLENAECFDAALFGYSRQEAESIDPQQRLFLQAV
WQALEHAGYAPGTVPHKTGVFASSRMSTYPGREALNVTEVAQVKGLQSLMGNDKDYIATR
AAYKLNLHGPALSVQTACSSSLVAVHLACESLRAGESDMAVAGGVALSFPQQAGYRYQPG
MIFSPDGRCRPFDASAEGTWAGNGLGCVVLRRLRDALLSGDPIISVILSSAVNNDGNRKV
GYTAPSAAGQQAVIEEALMLAAIDDKQVGYIETHGTGTPLGDAIEMEALRNVYAPRPQDQ
RCALGSVKSNMGHLDTAAGIAGLLKTVLAVSRGQIPPMLHFHTPNPALKLEESPFTIPLA
AQEWPDEMRYAGVSSFGIGGTNCHMIVASIPYALKARLPQTDGGDKSRALLLSAASDSAL
RRLAADYAGALRQNVDANNLAFTALYARRLDLPFRLAAPLNTETAAALSAWATEKSGPPV
YSGHGACGKQVWLFTGQGSHWRTMGQAMYQHSAAFADTLDRCFSACKEILAPALQEAMFN
PDSALLDNMAWAQPAIVAFEIAMAAQWSAEGLKPDFAIGHSVGEFAAAVVCGHYTIEQVM
PLVCQRGALMQQCASGAMVAVFAEEDALMPLARRFELDLAANNGTQHTVFSGPEARLAAF
CAALSQQDISYRRLSVTGAAHSALLEPILDRFQAACAGLHAAPGQIQLISTLTAAAIDES
ALNQADYWRRHMRQPVRFIQSIQVAHKLGASVFLEMGPDAQLVASGQREYRDNVFWIASA
RRHKEASDVLNQALLRLYAAGVALPWADLLAGDGQRISAPCYPFDTERYWKESASHASEP
ADAALSAGLQVASTAATALDLPRLEALKQCATRLHAIYVDQLVRRCTGDTIENGVDATTI
MRRGRLLPRYQQLLRRLLNNCVVDGDYRCTDGRYYRARPIEHEQRESLLTELAGYCEGFQ
AIPDTIARAGDRLYEMMSGAEEPVAIIFPQGASDGVEVLYQEFSFGRYFNQIAAGVLRGI
VQTRQSHQPLRILEVGGGTGGTTAWLLPELEEESALEYHFTDISALFTRRAQQKFARYDF
VHYNELDLEKEAQSQGFRAQSYDLIVAANVIHATRHIGRTLDNLRPLLKPGGRLLMREIT
QPMRLFDFVFGPLVLPLQDIDARKGELFLTTGQWEQQCRHAGFSKVDWLPQDGSQTAGMS
EHIILATLPGKPVSEVALTAQSEPVLGQALTADGYYLADWSDCARQPERFNARWQEAWRL
LSQRHGDDLPVVELPLVAVPEWLGQVRLSWRHEAFFRGRMRVEARHPDGEWRPLSPATRL
PAPQTHYQWQWSTLNVSNVDRPLAFCFSSDTLARGDELAQYGIINVQKASLGLMIVEETE
DVLALAEKVAEALSTCEAGLVVVTRRAWCIQENKGISPSHHALWALLRVAANEQPERLIA
AIDLDENDSWETLYQGLSAVSLSQRWLAVRDNNIWLPSLVPNEGCVAELPVNVFVGDDRW
HLVTGAFGGLGRLAVSWLREKGARRIALLAPRVDESWLRDVDDGQIRVCPCDVGDAGQLA
AVLEKLAANGGIAGAIHAAGVLADAPLQELDKDQLSAVFAVKAQAANQLLQTLRRHDGRY
LILYSSAAATLGAPGQSAHALACGYLDGLSRQFSTLDAPKILSIAWGAWGESGRAATPEM
LATLASRGMGVLSDAEGCWHLEQAVMRGAPWRLAMRVFTDKMPPLQQALFSAGAAEKPAP
SVILRADDNTFSGSLSDETAVMTWLKNRIAIQLRLNDPASLSPHQDLLQLGMDSLLFLEL
SSDIQHYLGVRINAERAWQDLSPGGLTQLICSQQTATPAASQPEMLQHDAGERYAPFPLT
PIQHAYWLGRTHLIGYGGVACHVLFEWDKRHDEFALAVLEKAWNQLIARHDMLRMVVDAD
GQQRILAETPKYRIPRHDLRQLPPEEQLIALEKRRHELSYRVLPADRWPLFELVVSEIDD
RHYRLHMNLDLLQFDVQSFKVMMDDLAQVWRGETLAPLDITFRDYVVAEQARRQTSEWHD
AWDYWQEKLPHLPLAPELPVVKTPAETPHFTTFKSTIAHKEWQALKQRWQQQGVTPSAAL
LTLFAATLERWSRTTAFTLNLTFFNRRPIHPQINQLIGDFTSVTLVDFSFSTPVTLQKQM
QQTQQRLWQNMAHSEMNGVEVIRELGRLRGSQRQPLMPVVFTSMLGMTLEGMTIDQAMSH
LLGEPCYVFTQTPQVWLDHQVMESDGELIFSWYCMDNVLKPGVAEAMFNDYCTLLQTVIA
RPESLNNVAEHISRQRWPLNARTDYDLRDIEQATLEFPGILQARAEMTAEDSLTLDFVMA
DDPSPSAAIPDEPALAQLAQPLPEQAQLDELDATWRWLEARALQGIAATLNRHGLFTAPE
MAHRFTEMMQALAAQASYQRLLRQWLHSLTQKEWLIREGEIWRCRIPLSDIPAPQQACPE
SQWSQALAQYLETCIARHDALFSGHCSPLELLFNEQHSVTDALYRDNPASACLNRYAAQI
AALCGAERILEVGAGTAATTAPMLTATRNTRQSYHFTDVSVQFLNDAREYFRDESRVSYA
LFDINQPLDFTAHPEEGYDLIVAANVLHDASHVVQALRRLRLLLKAGGRLLIVEATERNS
VFQLASVGFIEGLSGYRDFRRRDEKPMLTRSAWQEVLVQAGFENELAWPAQQSSPLRQHL
LVARSPGVNRPDKAAVSRYLQQRFGTGLPGLQIRQREELFTPLRAQSAARIEPAEPTSAA
EGNPAQEKQVAELWQALLSRPVARHHDFFELGGDSLMATRMVAQLNQRGIARANLQDLFT
HSTLSDFCAHLQACSSGEDNPVPICQGDGDETLFVFHASDGDISAWLPLSSALNTRVFGL
QAKSPRRFATLDQMIDEYAECIRRQQPHGPYVLAGWSYGAFLAAGAAQRLYAKGEQVRIA
LIDPVCRQDFCCENRAALLRLLAEGQTPLALPEHFDQQAPASQLADFIGLAKAAGMVSQN
LTLQAAETWLDNIAHLLRLLTEHTPGETVPVPGLIVYAAGRPAHWTPVETEWQTWINNAD
DYSIEASHWQIMMEAPHVQACAQHIKRWLCATSKQPENTL
>A0A231HF25|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia cerradoensis|TrEMBL
MSMVPLPPSRTAIAVVGLSCRLPQAPDPRAFWQLLRSGTDAITDTPPERWRSADESLRRG
GFLDTVTDFDAAFFGISAREAIEADPQQRLMLELAWQAFEDALGRRVGRTGVFVGAMADD
YRIVQQRRGDAAIAHHTGVGASRGVIANRISYLLGLRGPSLTVDTGQSSSLVAVHLAMES
LRRGESTTALAGGVQLNLVEDSAVRMSRFGGLSPDGRCYTFDARANGFVRGEGGGFVVLK
TVPQALADGDRIYAVLRGSAVGNDGAGKDLTTPTVDGQRAVLREAYRAAGVDPAAVAYVE
LHGTGTRVGDPVEAEALGTELGVPRRTPLLVGSAKTNIGHLEGAAGIAGLLKVVLAVHHG
ELPPSLNFRTPNPAVRWKDWRLEVVTDRRAWPDGERVAGVSAFGMGGTNCHVVVAAPEPA
VADRPASGHTPSGPAVAPRPVPWVFSAVSDAGLRALAADLRAGIPDSDAALPEIARTLAA
RSGLTERAVVFAPNAEELSAGLRQVSQSESRVVPARDVWSDDRELPVPAGPSVTFRELTE
LWDFPAAAAESVAFVFPGQGGQWAGMGARLWETSAVFRAWVRVADEVIAAEAGWSVREVL
LDVDGAPSLDRVDVVQPALFVTMVGIGLVWASWGIAPDAVVGHSQGEVAAAFVAGALTLG
DAVRVVAGRSALVARRLSGAGRMAVVWAPADAVRARLVGAVSVAAINGPATTVLTGAPEA
LAALVSRYDDEGVRVRWVDVDYASHSPQVEPVRAELVAELAAVRPRRTQVPFYSSVTGAR
LDAAGVDAEYWFRNLREPVNFAGAVDALLADGFRTFVECSPHPSLAGAVEDAAGPQVVVL
SSLRRDDGGANRLLESLAQAWVAGVGVDWASVVGPGPRRRAPEYSFRRTTFWPGAATAAE
PGRPDPGARWHALPPARRRRELLGLIRAEAAAVGAADISDAAVSFTGSGFDSVMAIELRN
RLSLATGLSLPASVLFDHPSPDRLADHLANLLNDSPAQELPTPLAGAGVQDTSTDDADAI
AIVSMACRYPGGADTPEKLWDLVVAGRDAIGPFPADRGWDLAGLFDDEPGRVGKSSARAG
GFLYDAPQFDAELFGISPREAAAMDPQQRLLLETSWELFERAGLNVHALRGSDTGVFIGA
MAPDYGPRMSEAGERAAGYVLTGTTGGVASGRISYVYGFTGPTLTVDTACSSSLVALHLA
AAALRRGECSLAVAGGATVMSTPGIFIEFSQQRGLSPDGRCRAFGAGADGTGWAEGVGVL
LLERLSDARRHGHRVLAVLRGSAVNSDGASNGLTAPNGPSQERVIRRALADAGLTTADVD
VVEGHGTGTALGDPIEAHALLATYGRDRAGGHPLRLGSLKSNIGHSQAAAGVGGVIKMVQ
ALRHGVLPRTLHADRPSPLIDWAAGQVELLTRNEPWPASGRPRRAAVSSFGIGGTNAHVV
LEQAPAVADSAPVARSGPVPWIVSAASADGLREHAAALADFARRPDAPHPRSVAAALATR
ATLAERAVVIGRTPEDLAEALHRIADAPTRVVAAVPTPASHEDEPVPLGTAALTFPELLA
AFGFRFEPVEGVAVLFPGQGGQWAGMGAQLWESSPVFRAWVSTLDVVVREAAGWSVRDVL
LDRDGAEPLDRVDVVQVALFAMSVGVALVWASWGIGAEAVAGHSQGEVAAAFVAGGLTLA
DAVHIVVTRSRLIARKLSGSGGMAVVWAAPERIRPRLVDGVVVAAVNGPEVVVLSGDSQP
LRTVADGVEAEGVRVRWVDVDYASHSPAVEAVHDELVDRLVSLRPRSSAVAFYSSVRGGL
LDTAELDAAYWFRNLREPVDFTGAVAALAADGFRFFVESSPHPGLVGAVEETVGADGVVV
GSLRRGEGGLDRLLTAAGDGWVRGLPVDWPRVIGAAPDADAPTYTFRRQRYWLSAEPPRA
RIADDWRYRVDWRALPPATARPAGRWLLVGAPDEVRDALSRSRLEVTDDRDSGPLRGALS
FRSDIGETLELLRGLPESVPLYVITRGAVGVAGEPLADPAQSVLWGLGYSLALARPDRWG
GLIDLPATPLDADLVATLEHALSTATENQMAVRPSGLFARRLVRAHARNDRAPWRSRGSA
LVTGGTGAIGARVARWLLRTGTDHVVLLSRSGPAAPNAAALRAEFGSAVTIVACDITDRA
ALDRVIGDIADLRTVVHAAGVVDSTPVTEVTAADIAHVIGPKAVAAQYLHELTGELDAFV
LFSSGAAVWGSADQGVYGAANAYLDALAAHRRGLGLPATSIAWGAWDGGGMAAEPGAAQR
WRRQGVLPMDPDAALDHLERALRAGESGLLVADIDWSRLAPVLSAARPLRLLAELPEAQP
AAEPAEATTGRSFAERLAALPEDEADRALLELVRAEIAAVLGYDAPRADDDDRNLLELGF
DSLTTVELRNRLNAATGLSIAVTFLFDHATASELAKALGSELALTDEPPVAPADPVSMLF
HQAFESGKFAEGMALLREAARLRPMFDSAATVPHPDPVTLADGDGGPQVICFSALVAMTG
AQVYTRFADEFRGQRKVSALPAPGFVSGDSLPATIEAVIDLQTEIVRPIAARAEVVLTGT
SSGGWLAHAVAARLERDGLRVAGVVLLDTYLPDADLLRRAQHRVIGGVLDRQAGFGLADG
VRLSAMGWYIPLFAHWRPEPITAPTLLVRASEPLRDHTGAALEDLDWRSAWTLPHTVVDV
PGDHFTILEEHAASTARAVREWLDR
>Q3M3U7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Trichormus variabilis (strain ATCC 29413 / PCC 7937)|TrEMBL
MEPIAIIGIGCRFPGADSPQAFWQLLSQGVDAITEIPADRWNIDEFYDRNPETPGKMNSR
YGGFLSQVDRFDPHFFGISPREALLMDPQQRLLLEVAWEALEDAGIVREQLTGSKTGVFV
GISTNDYSRIHPEFDSNPQGYDLTGNCINIAAGRLSYLFNLRGPSLAVDTACSSSLVAVH
LACQSIWNQESSMAIASGVNLVLSPIGNIALSKLKALSPDGRCKTFDESANGYVRSEGAG
CIILKPLAQALANHDPIYAVIRGSAINHDGRSKGLTVPYGPAQEALIRQALQQAQVQPKE
ISYVELHGTGTPLGDPIEAMAIGAVLGEGRDPDHPCLVGAVKSNIGHLEAAAGIASIIKM
ALALKYQQIPPSLHFHQPNPYIPFDQLPLRVQTSLIPWPKSQYGAKAGVSSFGFSGTNAH
VILEAYSSFSPTEQPTSKLPHLLPLSAHTPAAVQTLALGYQDLINAQKLTPEFVQNLCYS
ASVRRTHQSYRSAVVVNSPEDLPSCLQALTTADITTQVKQAKRKHKVAFVFSGQGPQWWA
MGRQLLAQEPVFRAVIEECDTLIQKYAQWSLLAEFAVPESHSRFQETEIAQPALFALQVG
LAHLWRAWGIEPKAVVGHSLGEVAAAHFAGVLSLEDAIYLICHRGRLMQQATGNGKMLAV
ELPVTEVEPLLAAWAGKLEIAAINSPTATVISGQSQALEVFVTQLQQQHPDIFYKELPVN
YAFHSQQMAPFAEALVEKLSHIQPQTGSLAIFSTVTGDKQAGQKFNGDYWGQNLRHTVCF
APALTALIQSGYTQFIEISPHPVLSGYINACLKKQEVDGVVLPSLKRGFGERATLLKSLG
TLYTLGHAVNWQSLYPDGCQMVDLPLYPWQRESYWISESQPQFQKAQPASSLLNLLLAGK
TEQLTQELSNHHQLSPEAKQLIPQLIELLATGKSTAKITQDLSNARYGIEWQLSPLTVDN
KISQAENWLIFSDNQGLGKELAAVVNDSCILVSSGESYEKLSSSHYQINPHQAADFQKLL
TDISQTVTKVVYLWGLENSQTQCYSLLYLVQALAKINGKIAPKLWIGTQQAQAVTTSCHP
DFSDHVEKLTPDLTPQPPSLLGKGEKSKPLSLQDTVGELIEGKTNHHKIENQEYYEAVGA
IRAK
>A0A060Q375|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia brasiliensis|TrEMBL
MSAFTTHETATEPIAIIGMACRYPGNSSSPQAFWDFLSAGATAVTDFPADRGWDLDRLRA
DPARAGASAVHRGGFLDAAAFDAAFFGISPREATAMHPEQRLLLEVAWEACEHAMLDPHS
LRDTDTGVYAAQLSTAYGPPMHLAPEGAAGLMLTGNIAAALSGRIAYTLGVTGPAITIDT
ASSGSLVAIHLAVQALRARACERALAGGVSVMPTPGFFTEFTRQQGLAPDGRAKPFAADA
DGTVWSEGAGMIMLTRLSDARANGHRVLAVIRGSAVNSDGASTGLTAPSATAQQRLITRA
LADAGLTAADVDAVEAHGSGTRAGDRAEATALVETYGVDRARDRPLRVGSVKSNIGHAQA
AAGVAGLIKSVLALQHEKLPGLVHFGTPSPEVDWAAAAVLPLAETEPWLRGDRPRRCGVS
SFGVAGTNAHVIVEEAPEFEAADPAEAVPADVQPWVISAHSETALRAQAARLLATAEPER
PADVGYSLAVTRSRFDHRAVIVGTDRAELVSGLEAVVRGVPASQVVRGTAWSEPRPVFVF
PGQGGQWPGMATALAKSSAEFAGHLADCAAALRPYLPWSLSDVLDGVAGAPSIERVDVVQ
PVLWAVMVALARVWQGYGVQPAAVVGHSQGEIAAACVAGALSLDDGARVVARRSQVVLAL
SGTGAMLSLGLGAEAARKRMARWGTRLDIAAINGPGAVAVCGEPAAIAQLQAECERDDIR
ARPINADYASHSSHVDPVERELRETLAPVRPRTGAVPLYSTVTGAPIRHDALDAGYWWQN
LRRPVQFEAATRSLLDAGHHVFIEISPHPVLAFGLEGTIEAAGADAAVLATLRRDDGGLD
RLTMSLAQAEAHGVAVDWHTYFAPVQPRRIPLPTYAFQRQRYWLDAPGAPAADAAPVADT
DPEPAAPSTTPRDIRELVAREIAAVLGLDTAAEVSAGLSFKALGFESMTSVELRNRLSVA
LGRRLPTTLIYDYPSPRALADHLAGLGGDPSDNPDRDAAEAPTARGPRGFDDMDGAELVR
LALGKEAR
>A0A653F858|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium smegmatis|TrEMBL
MPNTDHTSRQPLAIVGIGCRFPGGADSAQRYWDLLCNNIDATREVPENRWNAAKYHDPNP
AKIGKIVTRRGGFLDQIDQFDPQFFGISPREAHSLDPQQRLLLQATWEALEDGGIPADEL
AGTDVGVFVGGFTLDYQLLQNQGRTSRYRFKPHSATGMMMTMLANRISHAFDFRGPSMAI
DTACSSSLVAVHLAAQSIWDGDCDVALAGGVNIMVGPNTAIAESKSGFLSPEGRSKAFSD
TADGYARGEGGAVVVIKPLAHALRDGDDIYAQILGTAVSQDGHTDGITVPNEEAQEAAIR
MALQRAGVEPNDVAYVEAHGTGTPVGDPIEMRALAGALTTDRDATRPLVIGSVKTNIGHL
EAGAGVAGLIKAALIVKHGHIPANLHLKNPTRHVSLTELKLDIPTIGRPFPECDRRIAGI
NSFGFGGTNAHVVLAEPPAARHSAETGDHRVLTVLPISARSEEALVATAGRLAGHLAAHP
EVTLADLGYTLSHRRAHLNHRHTFVVDSIDEARRQLQAVADGGQISAGRAGEARLAFVCT
GMGPQWWQMCRGLLDVFPVFTDSIHRTDRELSRYADWSLLEELTRDEASSRMGETEFAQP
ANFAIQVALAEQLAHFGITPDAVIGHSAGEVAAHHIAGLLTFEQAVHVIYHRSRLQQRTT
GQGRMLAVGLDAETLMQILDEKILDQFGRRVSVAAINSPSAVTVAGDADVLEDIARHLDE
AQIFNRYLAVKVPYHTHYMETIKDDLHTAFASLSSKAATLPLYSTVTGELLDRYDAGAAY
WWQNTRATVLFEPAMRRMLDDGYTHFVELGPHPVLAASILESAGTQRVSVDASQRRGQDD
ARTLLNCVGALHSRGHEVAWDMVQPRAGAHPVKLPSYPWQTKRFWNDTHEAEEALFYRPV
HPLLGQPVRAVHPTWEAEFSTLTVPFLADHQVQGSVVVPGAVYVEMALAAGRETYGSDLS
VDNLVLHRAVILDDTCDPVIRTTVDQDDGSVEFAALIATADTDLKWVITATAELNTLPRA
PRAGDTGGGAVTSTDGDTFYQRTQALGFDYGEAFRSVASVTAGRDWAVAQIDIPQSISAD
VDTYRFHPALIDGAFQTLFGAPFSGQEENTDPYLPTRIRHCAVYGPPAEHMTVRARVLSA
THDAVECDITITDPSGGVLAAFDGFTVQSLSASSRMSADHIDKGLFALEWSPVTDTPDTA
HGDESTWLILTDNGGVGEAIADGLRLRGHHVHTVAHDPTGEIDWPDMLATHLSGERTGLI
DCWPLEVTDAATDPAGTATVLRIVKALATLDGVTPRLYLVTANAQPAAGTELTGTELTGV
EQAAFWGLGRVIGHQELGEYWGGLIDIDHADAPSSTAEQICGHVLGDGAEDQIALRGNQI
LAPRLRPCSGLTKPFPTKLTADATYVVTGGAGALGRVVATYLAERGARHITLLGRSPISP
RDRWASITEDDAHHATVDAIRAIERLGAHVSTASVDITDSDQVRAWLREHTGSGGRPVRG
IVHAAGSVRDQLLVNMGEDDFAEVLAPKITGTRVLHNVFEDHDLEFFVMFGSAGSTIAAP
GQGNYAAANAFLDAFAHHRQGLGLPALTIGWGPWSVGMVEELGLEKVYAQRGIELITPAV
GARIIDRLLSQSVPAVVAMNADWSRARQVGFGGLVPKMFGELGTADTVGGQDGVGPSILE
LLAHTADADRPAVIAEQVRRLVAAVFDCAVTDIEPDDMLDDIGLDSMMAMDFRVRINSAF
SIDLPVLEILRGVSVNSLSARILAELRDIHGVAPVEPDTGETASEPTTTDDDVERLLQDL
SEAEMRQLLAELEASGTEAGGAIS
>B1G608|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Paraburkholderia graminis (strain ATCC 700544 / DSM 17151 / LMG 18924 / NCIMB 13744 / C4D1M)|TrEMBL
MHASSSGDNGMDNSNVFAGRIAIVGMSCRFPGGASCASTYWDFLNSGQSAIRETPPERFD
IDAFYSPDPDEPGTTYSRVAGYVDDPFFFDRRFFRTSAAEAMEMDPQQRWMLELTWAALE
NAGLVPSQLRGTSAGVFMTTGEADYGRRTVWSGDPRGITTYSKLGNLRAMAPGRVAHILG
LGGPAIFVDTTCSSSLVAIHLAAQSLREGDCDVAIAGGVNLILGPEETIGVARLKAMSPS
GQCRPFDANADGYIRGEGGGVIVMKRLEDALAHGDRIDAVLAGSAVNSDGASNGLTAPNG
AAQEAVIRRALARARARPQDVAYIEAHGTGTSLGDPIELSALRNVYARSVARPKPILVGS
VKSQVGHLEGAAGMAGIIKAILILRHRHVPAQVNFSTPNPRFRWSDEQLDVARCRAPLDD
PRALVGVSGFGITGTNVHLILAPRPTREVAANDADRQRVLTLSGRSAEARQRLAREFRTK
LAASPVSLRDVCYTASVRREKLRPSRRVRRYDESGFHPGNRRFSASRCVGHLARRQQPEK
AAPCLCLPWAGLMASRRWGGVV
>A0A157M9J2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Bordetella ansorpii|TrEMBL
MPKRVAVIGLSFRFPSTDIQNYWNDLLEGKDLVTEVESRRWAHDAYLHPSKEHPGTSYTF
AAGSIGDVSGFDADFFGISPREAALMDPQQRLLLEMCWETIESAGIKPSAMRGSDCGVYI
GIASADYSYRLAEDFNALDSSFATGNTASIAANRLSYVFDLHGPSMAVDTACSSSLVAFH
QACAAISSGEVSQAIAGGVSLHLHPYGFITFSKASMLSPNGRCRVFDASGDGYVRSEGGG
LFLLKDYDQAVADGNPILAVVAGTSVNTDGRKSGLTVPNADAQIALMRQVYQRAGIDPAQ
IDYIEAHGTGTAVGDPIEARAIGMALGRARGAEAAPLPIGSIKSNLGHLEAASGVAGLVK
AIYSLKYRTVPATIGIRTPNPNIRFDDWNIEVVTRARKLRGTGTLTIGVNSFGFGGANAH
AILQTPPQAPAARAAQLTSTTAIPVVVTGRTAAALHDAARDMAQVLRSQPARALYDIAYH
AARRRDWHDERAVVYGTDSEAIAQLLDQFAADEAPKHLVSTGQRLAQSQGPVFVYSGNGS
QWSGMGRKLMGDPLFAETVEEVDALFREYADWSIAAELRRDDGPSAYDRTEIAQPALFAV
QLGVTRMLAKRGIRPVAVVGHSVGEVAAAWACGALSLPDAVAVIFHRSRLQGATRGNGRM
AAVGIDATAAAALIAELRLDEAVCVAGSNSPRGATLAGDPGALEQIGKTLADQRLFYRRL
DLDYAFHSSAMDTLEGPLLQSLDAIAPLAGHIPFFSTVTGAQADGTTLDGAYWWHNIRRP
VRFAQALAALTAQGYTVYAEIGPHPVLRGYVNDSLKAAGLAGRVVNTCTRGDDDPARVRD
ATGQLLLSGAQVDWPFLFPWEGRHVTMPAYPWQRERHWHPVTPQALGQLERVRAHELLGY
PLRQHDLTWENQLDTRCVPWLGHHVVGDATVFPGSGFAEIALAAARQWQPGEFADIEELE
IHAPLLLDAAPSKLVRMALDASDGRFSLRGKEVGSTDPWTVHASGRVLTEARGMPAEHTA
PSLPLRPHDFTGADHLALTHLAGLDYGSAFQAVAQGWIEPNGTVCALLQPDATLSESLPG
SLLHPALLDCTFQLIIHMMKDDPVLGQGIAFVPAKIGRLRWRQGGVPHQVRARLLSRAPH
SLTAEFELFDAQGSLIAVIEQARFRSVRLSKAAVDHLSFLDYVAVPVPHPLKAVQANAAL
QPSRLEDALRETLRQAAKDGVHERYQHEVDPLLDGLCDRYATQALYGLSRNGRLTSAALQ
ACRDAAPQSASLLDWLVARAERTGDLTPDGRNQWRVTAPREDDPRITDIWNSLVREYSDY
FPVVHAVGRVGLHLPALLAGTQPFADVCPRGVTPSALARQIIGEAASQRISESLCAQLTL
AMQTRPAGQRVSILEIGNSQPLFADGLCHALDTASCDYIYATPSRAALDEAARLQDRHPG
LRTVLIEPAQPASGPAADLILLHSDFDTPEAITHALQYAHGNLKPGATLMLLGAHPAAWL
DFIFGAQQNWWTSDLNGGKVSTQYPLAYWQALLLQRGFVCRAPLEFVPGGACGPYLLMAG
LDAAPSEQAALPAVDGGWLLLSGTSRSYRREQTQSLAKRLGETGAPVMIQENCTPESLQA
VLSQALPRLGRLHGVVLLDGLGQQRADDTPRQLLAEQVRRCALAAGLAQACEQAGLTPTL
WLLTTGAAPFMPDGGSSPAALNDAALWNYGRTLLNEAAGFSVRLVDLPLSGPLPLDALLL
ELTAPDAEQEVALDADGARHVPRLQQTARPGTLPASLKAGDDSTLSLGFDMPGQLRNLRW
SAQPRTAPGAEQVEVRIQATGLNFRDVMYALGLLSDEAIENGFAGPTLGLEFAGIVERVG
SSVTDYQPGDAVVGFGPASFGNIALTHTNGIARIPDGMSFEAAATIPSTFFTVYYALHHL
ARLEEGEKVLIHGAAGGVGIAAIQYAQWVGAEIHATAGSDEKRDFLRLMGVEHIYDSRSL
SFADDILAETGGRGVDVVLNSLAGEAINRNLRVLKPFGRFLELGKRDFYENTRIGLRPFR
NNISYFGIDADQLMQERPSLTRRLFAEVMQRFQDGVLHPLPYQAFDANNVVDAFRHMQQA
RQIGKIVVTYRNGIRDARRPAALRGTLELSPHATYLVTGGLSGFGLRTANWLADKGARNL
VLLTRSGLSSQAAQQAVDALRARGVTVHAPACDVTDREALSGVLAEVAAGMPALRGVVHA
AMVIDDGLVRSTNAAQIERVLAPKVLGALHLDELTRGMPLDFFVFYSSGTTLFGNPGQAN
YVAANGWLEAMARHRVSQGLPATCVRWGAIDDVGYLARNKKVKDALQGRMGGTALSSDLA
LRVLEDMLLSNTPDLGVLELDWRALARFLPSAGSPKFSWIARRASTGEADDAGSPDIANM
LATLDDDALHHAFIDMLKSEVGEILRVPVDKIDPQRSIYDMGLDSLMGVELIVAVENRFG
IRLPVMALNESPTTARLASKLIELLRGDNTEQPDAVTSQIAQVVAQHIDDDVPSEVVAQL
ADDLKAGPELSTQRMIH
>S0G2L9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Desulfotignum phosphitoxidans DSM 13687|TrEMBL
MLTEHQNITIAFVRRPEKITPAVIQMAQQTGTRAIFDFSEEKSADNLVSLLRKTDPAGLV
RDIKISAPALMDLSLGRTIKETGIQTLWVECPPWFSQEDTALFLNKLGEMSKNYGCFPIT
GDTALITKMLKPGSGIERIVLKGCEAAGFVGRETTMTLYSMAREMQKSAATPFDIFIWGG
VFLPEAAAAFVSTGAAGIVFESIHWLTDQAGVDDSQREQLSRLRPDATDMVGLDVQVPCR
LFNKGNSLAFKKIKAYEDALCSAADMEDTRLSFANRVTAGAVHPLKSRFSKNEIIPLGVE
AAFAGAFVNRFGDRTGEAVTAFIKEMHQLCRLAEEKKNGFLDSPVAREMGTRYPFIQGAM
SWITDIPEFALRVADAGGLPTIALGLMDAEALDQRLGTLPRIMGSRPYAVNVVSLAENPF
KGLHLAWIKKHRPRFAVIAGGDLSTVRELMACGIDVMYIAPDEALLTLALKQGVRYVICE
GYEAGGHVGPHSTLTLAQMVLDMKRRTPSLFHNCRIILAGGIFNRETAFMAAMLGADAIQ
MGTAYLATQEIIETGALTPLYQQMILKSPLAGTVVSGRNTGLRVRSLKTPGMESILSLER
EFAAGLQDETSFRERMEKMAAGSLFMAARGMDGPGEIVLDEQTCIERGQFMSGSCAGLIR
DVDNLESFHHELARGSLLMHQPVVNSTETPLELPVAGIKPDPKRFTPNREVHERIAITGM
GIVNTLGKSPEEIWSASLAMKSGITKVPLSRWDHALYYDPKPLMPDKTYCRVGAFLDFPI
DRTELGIPPHDFRTMTQATRISMWLADRAIRASGILTSDIPRERIAVLISQNSGEAASTL
PDIIIRAYVHDIMAGIKKAVDLTPDQVQAIEQAIRSGRTALDDTTLLGRLNCAAAGFICK
KYGFMGPSHAVSAACATSLVALYSAIQMIKNGIIDAAVVGGGEDTLSHLHFLEFSALGAL
YGLSGRERPARETSCPFDAHRDGMVLGEGGAMIVIERESVARARGALVNAFVTGMGASNN
PFGMVESSRVSQQMAIRASFKGTSYGPDAVDMVECHATSTRQGDLEEVRALKGFYHSPRR
TVLTAFKSQIGHTLGASGIGGLIRGVMAMKAGIFPPTLNYRHPDPEINLENSGLIVSSAP
LDWKNRNGEPRRMEVNAFGFGGSNYVVQVEQAMDETDTVMVSPGTQKISEVRANQDPKVA
PPLALVFPGQGAQYGGMGQELYTSFPVIKEWLDRAAAVADFDLLHLMFHDQEKNLQKTRW
QQPAMFALENAMARYLIALGIRPVAMAGHSLGELTALCLAGVYSFEDGFRIVNKRALCMD
KAAAANIDPGVMAATDAPLDLLNKMIKDDNDIHIGNINSPFQTVLSGSTGAIRNFCKNLK
EMGHRTTLLRVSMAFHSPAMQVIHDELAAYIAGIAFHPPQIPVISNTTRKPYPADPHEIK
KILMAHLESTVHWMDNTRFLWNTHGARLFVEVGPGEVLSNLIADTLPGSSCIQTCVRSSE
ALTFKAALARLLAQGHLKETPGDLSSGMKSTFSDFQPPEFRKPVAPGTDDPSERDDLMEK
LIQIIMDATGFNRDEIQPDMDLRKDLSIRSSRLPIIMDAVERQFNITIELEDFIDVRTVK
DIAEEISRLTAGKQDSGLHTATEALDLNPVPDKCDNASTDEAPLKRLVFDHATLEFENAV
PLELSPGESVLLLSPDVEDKVAEHAGDILRTDYGVTPFPMGFMQEIPDSGQAGHDIRTEN
GTLRAADTIRTLLPVSGMVITLGRKGAIRSSSMTDVSQLLKSFFLLLKAFLESSAKKFIV
LIYSAEDIGTPVQLLAEGMLGIFLSAAREYASVQFRTLEIQKNTHLQKAMHHALDRGCAV
VEMIHRDGKILTSEGHLAPSVFKDSSHLTLCPGDVVVIAGGGAGIGAHLARCLAPFMPRL
ILLGRTRIDPEMDPAEPFAEHAASGAVPMDSRALEIAQTLTDLHAAGIEAAYHTCDVTDP
EAVQAVLAEVIRCYGRIDGIIHSAGILRDGPVSRMTLDDFSTVTDIKFSGAWHLFLSAQN
AGLKFFAGLSSAAAIQGNPGQANYAAANRMMAALLRHLGKENKAVRFKALMLPPVQGAGM
ADDPEIQALLKQKGVGYIHLNELAGLFCRELFIAPPEDHWVMFMKKLPSVNTVLLNDRTR
PEPFGDLDSGLLSFAPGDFPMIEKISALDLGQEKLEACRSFSLEKDLWITDHRPFKFIKH
PIVSATMAIETFMEAARILYPHLRVTGVRNVRLMDMIECRPGVPRPARISCCRTGDRLEE
VLCDTTLSAQEISPTGRLMAHFALQCSGQVMLDGGGETPGQGFHDFPIRSDELRTQPMNR
KKVLKWYKDRSGLGGRYRVIEFLDGTGPGVIRGRTIYPETCDFADLVNAKYQYSPYLFEA
LLQLVCCHIAVTDPSEPRSMIPLEIGEMRCFRKVGTGEKIMLEARLRAQTDEVLTWDTRG
LDDQGETLMQISGLQMKWISD
>A0A7X5WZC5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces malaysiensis|TrEMBL
MSSAVDAGDLVIGITPFGEPDARLAAAVSRAGGLGVLDLGTSGRQALQAWEDIGEWVADG
RYGVRVAAGCPLTPSDLPDAPPIGTPTSGSSGGVSGPHTVVLGVDSPWPVEAVADRCRVL
AEVTDLAEALDAIRAGAHGLIARGSESGGRIGALGTFVLLQRLLADPRVSLPVWACGGIG
PRTAAASVLGGAAGVVLDTQLALLAESGLPEDRAAAIRSMDGSETTVLDGHRVLRRRGRA
SQTEPLLTVGQDGFLAGRFAERWRDAGRTVRGITEAVREAAYEAVRHGSAVSALCPGAPL
STRLGTRLPIAQGPMTRVSDQGAFASAVAAGGALPFIALALAGREQARTMLEEAAAALDG
RPWGVGVLGFAPEEIRNAQLEAVREIRPSHAIIAGGRPSQAKALERDGIATFLHVPSPGL
LGQFLQAGARRFVFEGSECGGHVGPRNSFPLWEAQIAVIEDFLDGAARDPQRTAGAEDAD
GLDGSDGGSDGAGIEIFFAGGVHDERSAAMVAALAAPLIRRGVAVGSLMGTAYLFTEEAV
AHGAVQPLFQRQVVAAEHTVLLETAPGHATRCVPSPFTESFDIVRERLRKEGLPDREVWE
RLERLNVGRLRIASKGVDRGPDGALAPVGEKGQLSGGMFMAGEVVVMRSATTTIDALHHA
VGAGAADFLTARAEAVCERLGVAPAPAAAEAPTPLDVAVVGMACMFPQAPDLASFWANVV
GGVDAVTEVPAERWDPAVHYTGGKDGASVAKSASKWGGFLPPIPFDPLRYGIPPASLGSI
EPVQLLALEAARRALDDAGYGDPGDGGRAFDRARTSVVFGAEAGSDLSNAQTLRAVLPRY
VHEVPRALTDQLPRLTEDSFPGMLANVISGRIANRLDLGGANYTVDAACASSLAAVDVAC
KELTAGTSDLVLCGGADLHNGINDYVLFSSVHALSPTGRSRTFDSSADGIALGEGVACVV
LKRLADAERDGDRIYAVVKGVGSSSDGRSLGLTAPRPEGQRAALERAYANARISPADVGL
IEAHGTGTVVGDRTELTVLGEVFTEAGAAPGACALGSVKSQIGHTKCAAGLAGLVKATMA
LHTGITPPTLHLARPNEAWDADRSPFAFHTRARPWAAAPAERVAGVSAFGFGGTNFHVVL
AAHGRGAPPAQGMDAWPAELFLFRGADRAAALRVVQETLDQLMANDTAGRPWRLRDLALT
ASRRADAGQEPVQAAVVASDLDDLAARLRQVLAGDPPGPGPRGADGSHLAPDATEGPGTA
EGPEGEPERGKVAFLFPGQGSQRPGMFADAFVTFPALQRHLRHGRSYADALYPPAAFDEG
GAAAQRTAITDTRVAQPALGIVGLAAYTLLTSAGVRPDMAAGHSYGELVALCAAGALDPR
TLPPLSAERAAAILGAAQADAEEPGTMAAVTAAPGEVEPVLRTAGLTERVVAANHNAPRQ
TVISGPERDIEEAVRLLREAGHSAKRIPVACAFHSPLVAAAGGRFAEALGRHPVRAAEFP
VWANRTAAPYEAEPDAIRAELAAQIGAPVRFVAQIEAMYEAGARIFVEAGPGTVLTRLVG
EILDGRPHLALACEGRRSGSDGPRGFLDTLARLAVAGVPVRTAWLFHGRDAVVAGSAPPP
KRPGWTVDGHLVRTANGELLPGALAPARRVMEATVSQTDRTGGGEYGGGDKDALISEFLR
TSREMMAAQRDVLLTYLGGAPGERPAAPPAPVAAATDLPAELAPVAVAPVAAEAPDPAGS
APATAPATGPDVLRAVSEIISERTGYPVDMIEPDLDLEADLSIDSIKRAEIAGELARRLG
VAGADTATLGDEELEELARARTTAAVTDWLTARLAPAPATIAPPPDEPEPVAQPVAEPVA
EPVAVAGVAPKRLRLMPVPLGAPDRGGSAPPDLTGRRFALLGGDGDGVAEAVATRLGERG
AETVVLAADHQLAEDDGRVDGVLLLDPLAAFGAPVLPEAFTPLQSALRRAPHWLLAIRRT
DPLDARTAGLRGVFRTVTREYPDTITRLVEFPADTADSADTPKPTAVAVSIDAIADGLLD
ELLAPDRTLPVVLRTPEGRRHSLDLVETPLGTLAGSGAGPAGDGAAEATALGLDRDAVVV
LVGGARGITARFAATLASAARCRIELLGRTPEPVGPEDPATAGARDETALRAALAARGGL
GPAEIQREAARILARREVTATVEELKALGARVRYRSVDFRDAEAVLQAVKQIHADHGRLD
GVVYGAGVIEDRLIEEKSAESFQRVYGTKVEGARTLLDALAELPEPPAFAVLFGSIAAVL
GNRGQVDYAAANDALETLGARWRDRTGRRALTVHWGPWAPAGVHGGMVTPELGREYARRG
VSLIDPEEGTLALLRELAWGEESTGSVVYTASGW
>A0A2G8XWI5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii COUG|TrEMBL
MANAEKLVKLHGLWFRSLWKWAEKIPHEDAVIWLDENGSKAASLTYQKLRREALIIATCL
RQVHCQPGDRAILCYPPSVSFVPAFLGCQICGLTAVPVYPPGSNDRDSDSIQRIVAMVKT
TRPSVVLSSSPLRYFLKEVFPGAAARCVSDIRWIFTDELPDHVEAGSAFELDSLDIKSET
PAFIQFSSGSTGNPKGCVVTHMALLHNIHLNWRMCGAFHPGTEESLYDLPVESYADFTEK
YQKHLVATWGHRLRSFSWLPVTHDMGLVGMLCVPLFFGCTAFFMSPIDFVRAPHSWLGGM
SKFGCSFTAAPDFAYALAARKVPDDLVLELNFEKILACVNGAEPIRPATIEAFLQKFAPA
GFQPWMMSPAYGLAEHTVGVTGRGSEGRKPMSPKIIEVNNEKVAQGDTVELFKRSGKQEN
EMRTKLIVGCGIPHEDVIVKIVDPRLLQELSEWQVGEVWVSSPSAASGYFGSPVETASTF
NLHLNTADGATRGDRSFLRTGDLGFLGDGELFITGRLKDVVILRGCNYYPQDIEEAVERC
DSVRKGGVMAFSISTTDDAEGLGVAAEIQKGSEKPAKLKLIYADIVRTVNKVLHLPLQRL
WLLRAGSLPKTTSGKPRRSEARRRLLQAERCDDILYSYTRNLSHSGHLPFRPGTFELDME
QKQEDSASTSKSEVNKSLVESLSTAKGARHTDDGFIFTNGQQNLHEAKKDQHGTSDSTLA
EPVSNAILDPITRVTDALLVTADGTSVHKDEEELSLVAECFACVTGVEKSCLRPDTPFLS
LGLDSLTAVELANEIQRRMKQPVEPFELFEFADLRSLALYLRNKKLDHGKDARGRQTKSS
PERSLGIVQVQRPSVFVTGVACALPGSCQTPDKLWEILDAGIDCVGPIPPNRNFCASQNF
AVIGEPRTANASFCVTEGGFLDDVDLFDNSFFGIPDAEAMTMDPQQRLLLMKAVEALHAA
GMATIDSRSAPIATFVGCCSTDWQRMNLGEQIQSFSATSHSASMLSNRLSYTLGLTGASI
TVDTACSSSLTALHCAMQELQHRHVPCHTAVVATVNLLLTTDVTLAFARAGFLSPTYRCK
TFDDAADGFVRSEGVVVFVLQTDVSETPTPSFKNQQEDNEGGQGECGTRIPASGYLCRIL
ASTVVHGGKTGSVTAPSGSSQELLYKQTFACAQVPPRAVDLVETHGTGTRLGDPIEISAL
CNSFAPDMETRKHRLVLGALKTNLGHLEGASGLAGLLKSVLCLNRQRVPPNLHLRKLNRF
IDFRSLPVLLPTKTVPLPASSSETKEAVALVTSLGFGGTYAQVAVQVPSTTGNEMLLRNQ
EPVQWNKKCFDVGKLVSQSNSFQSAVSHNDTKGPCFWEVGWEFLLEFDSITLTLPTLPEQ
APPAKWLVLTSPKAQQSFRKFSVNIFLPGIRMTFACLEELKAPEHLEAILKAETWTAIVS
TYTTETGSCMTDSSDLIGRTLQILQTYGQMASQSAVLPRILFLTQGCFQVGAAASLLRAS
PYNAGIIGFVRACRLEIESLSGRKAPIYLIDFAANGTLTETLSAVSKLLGMIDIRNVDET
EFAICGKRVFAPRLLPLHLGLEEILPAYDHYMDLTKKADESPAGTAKFPRLVEPANKACR
VRLLALCLDEIFPIEAISPASKAFELGESRPCTLPYGYRNRRQKAFLYQMERAFV
>G8SJL4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)|TrEMBL
MGQDETMSDDRLRGYLRRAVADLDDAKRRLREAEQSRHEPIAIVSAACRFPGGADTSERL
WDLLAAGTDAISDFPMDRGWDLAALYDPEPGTPGRTYVRTGGFLHDAADFDADFFRMSPR
EARETDPQQRLLLETAWEAVERAGIAPTALRGTPTGVFAGVVYHDYSTDGGPGGLASVAS
GRIAYLMDLTGPVVTVDTACSSSLVALHWAVRALRSGECSLALVGGATVMAGPASFVGFS
QDRGLSPDGRCRSFAAAADGTAWGEGAGMLLLERLGDARRNGHPVLAVVRGSAVNSDGAS
NGLTAPNGPAQQRLIRAALADARLRADQVDAVEAHGTGTTLGDPIEAEALLATYGRQRRD
GRPLWLGSVKSNIGHTQAAAGVGGIIKLLEALRHETLPPTLHVDEPSGHVDWTTGDVRLL
TEAVAWPAGDTPRRAAVSAFGLSGTNAHVILEEAPAEPAAGRVPPAAGSVPVLVSAHSAA
ALPAQAAALAAHLRARPDDRLSDLAYTVATGRAALPYRASVVAADPAGLLRGLDEIAAGE
RRPARHRPGGRTAVLFTGQGAQRLGMGRGLYERFPVFAGAFDEVLAGLVPGLRDVMWGGD
AAALDRTGHAQGALFAVEVALFRLVESWGVVPAAVAGHSIGEVAAAHVAGVLSLSDACAL
VVARSRLMQALPVGGAMTVVEASEAEIGPYLGRVDLAAVNGLTSVVVSGAADAVAEVAAV
FAGRGRRTRALRVSHAFHSTLMDPILDEFSTTIASLEYAVPAIPIVSTLTGRPATGDDLR
SADYWTRQLRQPVRYADAVRALHDTGVTIAVEIGPDGVLSAMGPGCLDPEAAVTFVPLLK
AGRPEPDELVGGLATAHDHGAAVDWPAFFAGTGAARTDLPTYRFQRSPYWRDTPAVTADP
LAPLHYRVEWAPVDIGPGALTGRWLVLHGWADRRVTTVLDALAAHGAEVVAIPVSGLDRP
AIAALLAAAPAALPAPVGVLSLLALDTTAHRDHPEISRGLADTVTLAQVLGDAGVTAPLW
CLTQHAVAAGDRHDVDAGQSAVWGLGAGLALERPDTWGGLIDLPPVLGPATAGRLAAVLS
GATGEDQVALRPDGAYARRLTRPSPGTTGDSWQPRGTVLVTGGTGALGGHVARWLATAGA
DRIVLVSRRGEAADGATELAAEITALGAEPVIVAGDVADRDALAAVLDRFPVDAVVHAAG
TAQPMAPLEELTLAGFAATAGAKTTGAVHLDALLADTPLDAFILFSSGSAVWGSAAQAAY
GSANAHLDGIAAARRARGGAAVSIGWGSWDAGMVDAPIAAAMRRIGAPAMNPALAVRALG
RVGAGADPQPVIADIQWDRFSPAYTLARPRPLLHDLPEAAVAPSAPTAAVDTLAALSAAD
RADAIDRLVRTAVAGLLGYADPDAVDTDRPFTDLGFDSVSAVGLRTRLNERTGRNLPSTL
VFDHVTPGALTDHLIGLYAADGAPPSAMDHLARLEQAVDAAAPDDPDRRPLAARLRALLG
RLDGAADADDVNQRLDGATADDVLAFIDAEFGS
>V5BCV6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii (strain ATCC 50861 / VEG)|TrEMBL
MASDLTQALLSCLEAVTEPDSEDTPNQRTDAEYRFCAVRQDDITFAEFLNRVSVQFEVPI
GPLAAKDYESFSSFVFHICELKKEKQVNVKTSSHHIIHRTNRYSTENEKASISIVGIACR
LPGNAKNPGDFWTVLVEGIDAIVPIPSKRWNHKEFSEGHSERGTIYVKEGGFIDGIEKFD
NGFFKISSSEARRMDPQQRMLLELSHEAFESAGLQAITDDNHKFGVFVGCSSSECLMLVP
EATVALCAAGMLALDSRCRPFDAAANGYGRGEGAVVFLLERQMYSPESRCKQKSLATIRG
HGTNHNGRSVSVTAPSDVAQKKLLEGVLRTASVEPQQVAYLEAHGTGTKLGDTIEFRAIK
SVFSTSRSVDNPLLIGSGKSNVGHLEGCAGAVGLLKALLVLYFREVPPTLHFKKISPLID
DEGFDYQIPTKRLTLAGDRPILAGVSSFGLGGCNAHVIIESVPKDREMDALSLSRRHIWD
HMEFPVFESADDGNSFGGLAMRHNVDLCNSTCNHLRRRSTSSLIGKCTLTPVSARLRRFT
AFSSGDGTPGLRVQQYGTTEGSSKANEPHAITEKQISRWTRDNRKGLYVEVESMKDELER
SFSLEDDNGSVTGSVQTEQTEPDQMANEVVNTVDEEAVQTLVLQTVRQILKEAVSIHRDV
SLKTLGIDSLAAVEFRDSLQESLGISLPASLIFDFPTIDDVCRFLAQKLQSGDGGERRNT
PTNLAQPRPSTSSETCVAVRGMSCRFPGAEDGTTESFWEMLHSDSDCIQEIPTSRFDAAS
IFDTDYDARDKIYVKAAGILRGADMFDNTFFKISEVEVRHLDPRQRILLEVAYDALVDSQ
VLGDQGLAAIDNEIVGVVIGCSGNDWNTFLQQHALSASSFSGPGTSPALLSNRVSYSLSL
RGPSLTVDTACSSSLVAIDIARQLLNASQCNLALVGGVQLLLTADTFIHYCRARMLSPDC
RCKTFDASANGYVRSEGCGVVLLENTHDRQVSKNTTYAWLLGSANNHVGKSASLTAPNGP
AQQAVILASLRSAHLQLTSQIHLIETHGTGTSLGDPIEIGALQAVYGQGTSADTPLVLGA
LKSRIGHTEGAAGIAGFIKLICSLRQRIAPPNLHLKTFNPHIDISTADSSRPFLFPTKAY
PLGTLMAGEKTEALLGAVSSFGFGGSNAHAIVEVPARQGPTGRDAAYAGLRGADAATEAH
QPMVWLFTGQGSQYVNMAKSLYETEESFRQTVKECSAYLATEKLLPTEGPSSLEDIIYPG
QDADAEEAEHLLMQTQYSQVAIFVVELALTRVLKERGLRPAAVLGHSLGEYAAAVTAGVF
SWRDALRVVAVRARIMSEQDPQDGVMAACRLSAAEVQAALDSDLKNLKSVAVAADNGPRS
VVVSGRRSEVEEVLSFFSISGRARFLRVSHAFHSPLMAGAVEPVSRLFERVEFSKPAIPF
ISSARGRLTITNELCDSMYWGQQVAVRSSLGRHRCCRSGWSASVTCEVVVC
>A0A0D2N079|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Monoraphidium neglectum|TrEMBL
MLYQTVLAASDPWEASQKLSGAGCAVALGSKRAGPAALVAAALAAARGALAAPGAGAAAL
TLGTGGHPSAGGALTRGALPGLLRTVQQEAASWHVAVLSDSTTPACASPTLALGDDGPQQ
QLTAVGSYGGRADACVLFAPVLRPAAVAAAEQLPPHQLVPQPRGAFSGLVPAAVDVSSAA
LAHGQIGLRVQAVGLNFRDVLNVLGMYPGDPGNPGGDCAGVVLATNPTATSTPHAVGQRV
FGLAVGSLGTAVACAADTMVAAPACLTFEEAASMPTVFITARAALRQVATARRGERVLLQ
AAAGGVGLAALQVLEATGAVVLGTAGGPPKRALLRSLGVAHAAGSRDTGFACDLAVAAGG
ADVVLHSLTSPGMVGGALALLRRGGRLVEIGKRDVWSGAAVAAQRPDVAYRLLAVDFLPD
CEVQAALRAVAAGAASGALRPLPLAAHPLSGVAAALRQLSQARQLGKVIVGGATNRPPAA
PAGRVLVTGGTGYLGSLVAAWLTTQQLGSVSLLARNARASRPLAQLLAGGSMMPVNVTQC
DAGLSADVAALLNSGEPIQAIFHAGGVLADATLQQLTLSGVRRTIAAKQTALGRLLALHQ
AQPAAQLVLFSSVASLLGSAGQANYAAANAALDAAAAALQAGGVAALSVQWGAWAGAGMA
ANDPRTAARVERMGMGLIEPRRGLAALEGALAAVATICAACAPVVTAVPFNWRRMAKRLG
SRVPTLFSEVGVAAGVGSSAAGAAPRRGRAPAARRGLHERAAVAAAEVGRQVEEAVRSIV
GREVAPDEPLMAAGLDSLGAVELRNALEGRLGLQLPGTLVFDYPSSAALSQYIGSRLAAS
GVSIDATGQAGAEDEEEDQQDWPEASAAAAAVADRVPRGLTPAGWAPTGAASVLAVSAFS
YRVPRDVWADGYAGDAAAAIPLERWDPDVAPAAALFADGGAPLRFGAFLPAGVAAAFDAA
AFGLSPPEAALMDPQQRLLLEAAAEALAGGAAAAASGMNSCGVFVGISSMDYQKLASRYG
GAVTAYSATGVSLSVAAGRLSFTFGLAGPSLAIDTACSSSLVAAHSASLSLGAAQCGRAL
VGGANLALFPDTPAMFKRAGMLAEDGRCKTLDAAADGYVRSEAVGVMLLQPFAAAEGASP
APLAVLAGSAVNQDGRSSGLTAPNGPAQQEVIRQALAAAGLAAADMCGVSTHGTGTSLGD
PIEVGALAAVFGGSGGKSGSSGCVAAPLVVAASKSWLGHAEPAAGVVGILQAAHQVCGLA
APPIAHLRTLNPLVASAMSSDGGRGWALPRQAGGLATAEAAALARCGVSAFAFQGTNAHV
VIATPSPANTSVRLAAPSLAAAQPQWRRSYLWLLPRPRALAAGGVSLAAAEAAGPGASGT
ATFACRLDAARLAFLWDHVVGGTPIFPAAGFLDAAASAAATLLLPTAAHDGTADDGRQLG
PHYHNNHHQQQLLLLTDAAIPAPLALAGKGGGRGSEQELLVSISLDSGRVRVTSRGGAGS
ATSAPTTHLAADAALARAAAPELAVQPAAVRVARLLGGPPITPSSGGYANSAASGALCAP
PQSAGDAHDFSLHPALLDSALQLGAAAAAATQAVGRQAAGSPGDTKVPVGLSALLVPLGD
SGAPACRPAFAATRAFTGESGQLSSSYWLVDKRGAATGAVDGLVAKAIPKPAQRRAQGQV
QDLQAAKDCLYQIDWVVDSPEAALDRIQEAGSEDQRAVEAACDLSLTARADGGLSATAAL
VAALQAQQPRPGAGAPLSVWTSGAEATVLHGASGGPAGRGVAGALVSAVLRTATQEQAAQ
VTAQSDASLHTCSGSGAGISSRAVRLSVMPGAAALPAGSRSSSAAAGATLTARLRPVAAA
EQLPPHQLVPRPRGAFSGLVPAAVDVSAVALAPGQIGLRVQAVGLNFRDVLNVLGMYPGD
PGNPGGDCAGVVLATNPTATSVPHAVGQRVFGLAVGSLGTAVACAADTMVAAPACLSFEE
AASMPTVFITARAALRQVAAAQHGERVLLQAAAGGVGLAALQVLEATGAMALGTAGGPPK
RALLRSLGVAHAASSRDTGFACDLAVAAGGADVVLNSLTSPGMVGGALALLRRGGRLVEI
GKRDVWSGAAVAAQRPDVAYSLLAVDFLPDCEVQAALRAVAAGAGSGALRSLPLAAHPLS
GVAAALRQLSQARHAGKVVVNAPASYQQQLFLAADGLVIVTGGLGTLGALVAGWLLQQGC
TRVALLGRAGKASALAQLPGGRADISVLASSPAQITFAACDVAAAADLWQQLLCGGGRAL
PILAVLHAGGVLQDATIAKQDAAGLRRVYAPKARAVQQWQGLLRSQPAAQQVLFSSVASL
LGSPGQANYAAANATLDAVAAALQAGGTPALSVQWGAWAGAGMAANDPQTAARVERLGMA
LIAPQQGLAALEGALAAVTRGGRGATLAPLGAIAAVPFKWAAFLAHRRPAPAFFSEFEAH
LQPASSRTPGGSRGSRSRSRGAAPWRPPVRQQGAASAVGAQVASAVAAVLGRPVGADEPL
VAAGLDSLGSVELRNALQAGLGGPGFRSTLQVELPPTLVFDYPSVSAITSLVASLGARGA
AGASPPSLDDVSDDEACPDDTPAALPPLAGAALGSGAAAGQGARLLVAVASFASRTAAGN
AVLSLEGRDASRRVPFERWSGADVEQLFDGLPPQFAVSLSDAALFDAAAFGVSAPEAALM
DPQQRLLLACAAEALLGGGTGPAASASLGIGTAVSSVTGVTGPVGAYVGVSSMDYNKLTL
KFLGSVTQNSSTGASLSVAAGRLSYTFGLRGPAMSVDTACSSSLVAAHTAVAALALGNCA
AALAGGVNLALSPDTSAAFAKAGMLAPDGRCKTLDASADGYVRAEAAGIFVLRPMDASGS
VAAPDSAAPTPLAVLAGSAVNQDGRSSGLTAPNGPAQQEVIRQALADAGVRASEVDLLQL
HGTGTSLGDPIEVGAAAAVFAPRAAPDGAAAPPPPPVPLALFTSKSSLGHAEPAAGAVGV
LHAAWAARHAALPPVLHLRAVNPFVAGTLSAGAAGTASGWQLPRQAAGRGCGKEGDGVVS
GVSSFAFQGTNAHLILKAPVAARSGAVGAGSGGVRAAVSWQPGRHWFMAPGTAPLLGALA
GGDGGGFRVLPAGALMMAAAAAVDAAAGGASADGRVLLGTDDQEIIYTVVWEAVEVQQEQ
HQLQQQQQQHKAQPSSLALAARRMAAADVSQALDAIAALQQACSAHGRPSLRLATTGAST
GVAAAAPSGYVSSDAGGAAAWAALRAAALEQPDWRLSALDSSNGGSRGTIFSLGRTAEIA
PDAAASLYGATTHGGARFAARLARAAVPSTPPAVRPLAGAALPQCGTYIITGGAGFLGAQ
VARWLLTVVGVSHVHIISRSGQLPSELSDLIMNPATSAQQRQAGMLTASKGDAAAAADFA
GAAAALAGAVCRLPVLGVLHAAGVLADGLLGGLSAASVRRAVAPKAQGLRLLMRALHRQP
LGTTVLFSSVASLLGSPGQANYAAANAALDAAATALQAGGVAALSVQWGAWAGAGMAAND
PQTAARAARLGVGMLQPLQALAALEAAVLSHSTRSGVAAPTALAVVPIQWRTFLARLPRQ
PPAAFFSTMHDRVAAGPTAAADAPPAQWPGQQQRPSAAATAESAALIAAQVEEAVADAVS
TVLGRQVAPDEPLMAAGLDSLGAVELRNLLQDSLGATLPQTLIFDAPTPAAMTAAIKSQL
LASLPMQEQQQQRQLAAAPLARTLGPLTAAPEARVIAIAAAAGRCAAGSAAPEAAPLAAA
ARVWDPVGVVPMERWDVERPPSSALAARFGAFMRGVEVFDATAFGVSAPEAALMDPQQRL
LLAAAAELLAPPPLAANASSLPASSFALGVYVGIASSDYASLVKAATSAGAPGAFHATAN
APSVASGRLAFAFNLQGPAISVDTACSASLVALHLARRALLESSGGGGGGGSESWGGGLE
GALVAGVHVQAAPTSSSYVYAAGMLSTSGRCKVLDADADGYVRGEAVHALLLRPFQVASP
ALAQAVGSTSAAPRPPPLAAILLGSAVNQDGRSSGLTAPNGPAQQEVIRQALAAAGVAAG
DVHLLSMHGTGTALGDPVEVNAAAETLLVGGGTPAAQPLSLLASKSWHGHAEPAAGLVAL
AHAASAAAAASRHPLLHLRTLNPYVAGMLESLAARRGGGGGGGGGGGLAARGAAVARQAA
PLALGRRGGGELAGDAAVVAGTSSFAFMVGWILGRDEITASARL
>I9NPQ5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pelosinus fermentans JBW45|TrEMBL
MKERKPKSQVKKNGNESKKTNSTGNCNDIAIVGIACRFPGAEDYQEFWRNLSQGVNSIRE
IDRWNLDEHYSPTGDDSKSISKWCGLLDNIDKFDNNFFNISPREADNMDPQQRILLEETW
RCIEDSGISLKKLQKKRTSVYVGAMALDSYLKSPSENDIDLYSGSGNYQFMLANRTSYYL
GLSGESKVIEAACASATVALCDAKKALAIGDSDYALVSGVNLHYSPIRYLMWSKNRMLSK
DGKCKTFDKDADGFVSGEGIGVLLLQPLDKAVQDKNNIYGVIKGCAVNHGGKAISISSPR
VEAQRDVILAAYEDAGFGPDTVTYIEAHGTGTSLGDPIEVEALTQAFQRSTIEKQFCKIG
SVKTNVGHLEAAAGMPGVIKVLMMMRHKKIPPSLNMKIINPIIDFENSPFSIASGLTNWV
SRKEGEPLRAGVSSFGFGGVNGHVLLEEYSEQIIESESLALSSYPFVLSAKNPHSLEDVL
HNWKEFTKSDSFSKIDFKDICLTLLTREDFSYRCGKLLKNKAELIEFLEKVTAVSVNKIT
DESWCLRVGEISWNDTDLAETIKEFPIFKEKFDQVLDSLDEFDVDHQIREGFFQKSWPKP
YVTLYSFILNYAIISTLIELGLSLNLITGLKKGLWISLAISGVIDIKEILAVLCGKKEVD
QLKFTRPIIPYYDPINRQVLNPYILDAQYIGSLIGELNISDEIVSHYLEKTNSLLTNQFT
FVKYLEQWDNKLKSVELDVKKLLNDETFLVPGEEGFSGRKLLLMIIMLSSLYKLNQKWSL
SERKLITDQRFYELLDLVLDEVMPKETLITLLLSKNPDLAAIATTLNIRQSKINNKTNYS
YLNEYSQKKIVIPDIQNWFEQMLVLEDLPLLPDMTYVNFGKLTSDPLASKVITFNPTAEL
SVALKESLVGLWTQGVGIQWQKLYPENSFKNIPLPVYAFNRSSFWLPDKAMEVKSPCLHL
EAAKNTTNLASIHPLLHQNISDFSEQRFSSTFTGQEFFLADHIVKGQRVLPGVAYLEMAR
AAVEQAVGGSQEGQTPPIRLKNVVWSRPITVGTHPVEVKIGLCPEDNGNIAYEIYSDSKD
INVEPIVHSQGNIVLSSAFQVPTLDLKVLRANCSQNSFSSSQCYEAYRTMGINYGPGHQG
IEKIYGGPDQVLAKLSLPASVSATQNQFVLHPSLLDSALQASISLLMGSGDLRLCLPFAL
QELEVFSKCTSTMWALIRYSKGSKAGDKVQKLDIDLCDDIGNVCVRMREFSSRILEGEVG
SANSTETLGTLTVTPCWKEQTAFQEATLPDYARHVVILCEADEVIQESIKTQMKEVRCLT
LQSEQRGIEERFQTYAVQVFEEVQSILKEKSVDKVLIQIVVSTQNEQQLFFGLSGLLKTA
QIENSKLIGQLIGVAGWGDSQRIIEKLRENSQSNDNQIQYKEGKRWVVDWREVEASQKEV
DIPWKDKGIYLITGGTGGLGFIFASEIAHKVKNATLILTGRSPLGDAKQAKLRELEGLGT
RIEYKQVDVTQKEAVSSLIQIIQKDFGNINGIIHGAGVKQDNFIIKKTKDELLEVLAPKV
TGLVNLDQESKDLKLDFFILFSSIAGSLGNLGQADYSTANSFMDMYARYRNALVDSKQRQ
GHTLSINWPLWKDGGMHVDEETEKMMMQSMGMIAMQTNTGIRTLYQGLASGKDQVMVMEG
KLIRMKQKLLSNQQSKSPAASDSTIGMDTNNMLDKVQVILMQAVSKLLNIKIEDIDAEAE
LSEYGFDSITFTEFANQLNQEYKLELTPTIFFERPTLHSFVEYLVEEHQAAFVSRFAAQT
KVEIPIQAMGDEVEEILTSKRQYSRFVRTVALSASEPLQPDKTIPEPIAIVGMSGSFPMS
KDVNEFWKNLKEGKDCITEIPKDRWDWQECYGDPKKDANKTNIKWGGFIDSIAEFDPFFF
GISPREAELMDPQQRLMMTYVWKVIEDAGYSAQSISGTNTGIFVGTMDVGYSRLLAKYNV
AFEAYSSTGMVSSVGPNRTSYFFDFHGPSEPIETACSSALVAIHRAVSAIESGSCEMAIA
GGVNTIPSSDYHISFSKAGMLSPDGRCKTFSNQANGYARGEGAGMIFLKKLKDAERAGDH
IYGIIRGTAENHGGHANSLTAPNPKAQAELLKAAYTKAAIDPRTVTYIEAHGTGTKLGDP
IEINGLKTAFKELYQRTGDSQVVNSHCGIGSVKTNIGHLEIASGIAGVIKVLLQLKHKTL
VKSLHCDTINPYIDLKDSPFYIVQKSKEWKAIQDVAGKELPRRAGVSSFGFGGVNAHVVI
EEYIPKKQERPQIVITPQNPAIIVLSAKSEEQLKIQAQQLVDFIGEIQISATGLADLAYT
LQVGREAMEERLAMSVGSSEELVEKLKSFVENQGGISNLYRGQAKRKKAKLTNSPAEEDM
ANTIGDWISQKKYGKLLELWVDGLNFDWNQLYGKIKPYRTSLPTYPFSRERYWVPKSDKQ
RKISSLVDQKNIQFDDAFFDQLLDEVMNNTISIDSALQKAKIMGFDNSRR
>A0A0J6WJ84|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium obuense|TrEMBL
MVSAADPNEPAPRFAVVGYAARLPGSPDADAFWDLLREGRDAISEVPADRWNAEAFYDAE
PGAPGKVATRRAGFVDDVTGFDAPFFGMSTREVRQMDPQHRLLLETSWHALEHAGIAPST
LAGSDTGVFVGLATHDYLGIMSDQLDYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV
DTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA
AADGYVRGEGCGIVVIKRLEDAVRDGDHIRAVIRGSAINQDGASGGLTVPNGVAQQRVIG
AALRRAGVAPRDVDYLEAHGTGTSLGDPIEAQAAGAALGEGREADRPLLIGSAKTNIGHL
EAAAGIAGVIKVILALEHETLPRHLNFDNPSPHIPWHRLPVQVLTEARPWHRADRPRIAG
VSSFGFAGTNAHVILEEAPLPAPGDIGQAAEGPQLLPLSAKTPTALSALAGAYREWWTAH
PEATLADVCFTAGVARAHTEHRAALVADTRDGALDLLDAVADDRPAPGLVRGEAHDVPKT
AWLFTGQGSQYPGMARGLYDSEPVFAATVDACADAVADLLDTPLLDVVFETDSAEAQDAL
RRTSYAQPALFAVEMGLARLWQSWGLQPDVVLGHSVGQYTAACVVGVFDLAAGARLMALR
GKLFGSLPAGGRMAAIFAPADRVEAVLDDIPTLSVAAYNGANTVLSGPAADLEKAVAALA
ADNIRCDWLETSHAFHSALLDPILDEFEVAANQFTYGTPQRILIDNRTGAALGRSTSLDG
AYWRRHARQPVQFAASIRTLAEMNCKVLVEIGPRPVLTAAALSAWPDPATTPRVIASLRP
TVDDRRQITEALADAYVLGHHPDFGAVSPATARVLDLPTYPFEHRRYWFRDENEQAEAPK
QASARTAAVALLEDGRIDELAILLGSSADDPLARDLLSRLAAQHNQQRDAQSISDARYEI
RWDALPIARLDAGDAPSWLVVGDDTAAIRPLIDLLTARGHQHRIVGLPTSDAEEAAFADT
MRAAADEPNLRILHVAALDDGESSMRSLLRMQHSVLPGTRRLFRAAAAADVRAPVWVLTR
GAQRVTDRDVVAPDQSCLWGFGRAAALETPVLWGGLADLGTGTAEEWSALIGQLSRADIG
VREDQLAIRADGVHVPRLTRRTGQPVTDALPIRSDATYLVTGGLGSVGLEIATYLASRGA
CHLVLTSRRMPSEAVSARLAALADQYGCQIEVVTADVADAHAVAKLLAPHADRPPLAGIV
HAAGEIGTSPMSTRDDTELDRVFAGKVWGAWNLSESARDLSLDFFLSTSSIASVWGSFGQ
TAYGAANAFLDGLSWSLRERGITATAVNFGPWASAGMADAQARARLEERGVLPLSPADAL
AGLTDAFAASLTQAVVARVDWSRFLPLYEQTGRRGFLAELKQEAPQQVSSVSTGGPTDLV
KRLTDAPVQQRRRLLIGYLRDAVAEVTRVDVDEIREDAGFFDIGMDSLMAVELRRRIETG
VGREIPATLAMDHPRIDAVADYLLGDVLGLTDAPAARPVTITAARTDEPIAIVAVSCRFP
GAPNPEAFWEVLAGGVDAIREVPEDRFDIDEFYDPDPDAPGKIYTRFGGFLDGIDGFDPE
FFGISPREAVWIEPQQRLMLETVWEGLERAGFSPASLRGSRTGVFTGVAANEYAHLLSAE
SIDKIQPHFITGNALNAISGRVAFALGLEGPAVAVDTACSSALVAVHQACQALHSGDCDL
AVAGGVNVLLSPVTTVAASRARMLSPVGRCKTFDASADGYVRSEGCGVLVLKRLSDAQRD
GDPIAAVIAGSGVNQDGASSGLTVPNGGAQQRLIGSVLARAGLSGGDVDYLEAHGTGTPL
GDPIEVQAAAAAYGDSRTEPLLMGSVKTNIGHTESASGAAGLIKVVLSLQNEMLPKSLHF
DTPSPHIPWDTLPVRVLGDTTPWQPTGRPRRAGVSSFGFTGTNAHVLVEEAPQAPEPAPA
AEPAVSVLPLSARSPEALEALAARYEAWVTAHPEADIADVCRTAGTGRSHFEHRAALVVE
STADARIGLADLVANRLRPGVVRGEHTHRPTTAWLFTGQGSQYPGMARELYQTQPVFAET
VDECAAAIEDLLPTPLVEVLFATDRETGGQAGKRLRHTSFAQPALFAIEMGLARLWQSWG
IEPDVVLGHSVGQYAAACVAGVFTLADGARLMAERGRLFGELPEGGRMVAVFADAGRVEQ
AAGAYPRVSVAAYNGPNTVLSGPGEDLEQIVATFTEDGIRCTWLETSHAFHSELLDPVLD
EFQSYAAHLDFASPTLPLVCNRTGAVLTGHATLDAEYWRRHSRQPVQFAESVRTVAGLGC
SVLMEIGPQPVLTGAAVQVWPEHVPAPRAIASLRKGVGDQRQIADALAGAYIAGHRPDFA
AVARREGRVLELPTYPFQHRRFWPKTAVIAMDGGATAAGSGILGAAKELASGDTIYTSRL
SVKTQPWLADHVIYGTVVVPGATYAAMALAAVGAPAHATDVFFYEPIILPEKASREVQLT
LHPAADSSQWSFQVHSRAYGEQGAEWALNAEGTVVAGRDETTSESGPVEDALERLTRMRP
QELFETFADLELAWGPNWSGSLKSLWLGDGEAIGDILVGEELTEHLGSEPMHPVLMDLCT
GVAFPAFPAVLAAEQGVSDLYLPLRYGQVSVQQPMPRRFYCRATWHQSALDSETQVFDLD
FVDRDGNRLGGIREFTVKRAPREALLRGLGGDTGRLLYTVGWHEVPLAEAETEAVPPNGT
WLIANFAELAALVSGAIAVDRATDTTPLGQVLTEAQQRGVGFSGVVWRAAGQQEGTPDVR
LEQEIAELLSAVHAVQSGEVTLPGGLWIATERAVACESGEPVDPVQAALWGFGRTAINEE
PALRPRLVDCDGSAEAVAVLARLVSAPVDEPEMAVRQGKLLASRLLPWSRSGHLSVPRAS
DYVLAPTERGAIDNLRLTETEVEPPADGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGG
DFAGIVTQIGDGVTGLTVGQRVYGSMQGAFASRFNVPGQFLAPIPDGISAVDAATIPAAA
LTVRLSFDWAQLTPGDKVLIHAASGGVGLAAVQMAQRCGAEVFATASTFKRDTLRRLGVK
YVYDSRTTEFADQILADTGGAGVDVVLNSLTGEGFIDATLRATAQGGRFAEIAKRDIWST
EQMAAARPDIAYEIVALDTVMFTEPDRIRDLLTEVSAGLAQGEWTPLPAEIYPLTEARSA
FRRMQQARHIGKIVVQMPAPLQPRSDRTYLITGGLGAIGLHTAAHLAQLGAADLVLTSRR
APSTEAQQLIDDIIEKHRCRVHVVTADVGDSDDVHRLLAHIRAELPPLGGVLHLAGVLDD
ALLSGLDLDRFRTTLAPKAFGASHLDRLTRDDDLEVFIVSSSVSSIFGSPGQANYATANA
YLDGLVAQRRAAGLPATGINFGPWGRGGMASSEAASANISAQGLIPLEPSAALGALAEVV
ANGTGQATVIKANWARAAKVLGAARPPILDLVLPRDGGEVTGDSELLRQLQEIPVPARAG
FVTEFLQREVQNFLRLAQPPAASARFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFD
YPTIGGLAEYLVGQLPDAEPAAAPAADAEQSG
>A0A498PHA3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium persicum|TrEMBL
MTTHRFPDNRVPVLLSAHEEELIGQDAAAILDYLEHLGRQPGTGDVTPAVAATLLRTRRV
RRHRAVVRAADRTELEAGLRALAAGEQHPLVARSSENAKTRTAFAFPGQGNQWASMGAEA
YQHLPAYRAEADRCAHAFVAAGLPSPLPYLVGEPPAGSAADTDHGWSQIDIQGAQFTHAA
SLAQVWRSCGVLPDLTIGHSLGEAAAAYVAGTITLADAVAVVAARATVVGRLSGRYGMAV
LSMGADQATRLITETPGWLELSAVNGPSSSVVSGDRDAVAAIVGRAEEDGIFARELTVDY
PGHTSKLESLRDTLRELLPASEFLDAPVEFVSSARGDVVTPHTDFTDYWYQNLRNTVRFD
QAAATARKRGAGTFVEMSAHPSLRYALAELAEDALIVVSGRRDGPVVDHLSANIAAAALA
NPGYRWRDVAGVGDQPLLRGFPTAPMRAIHLWATPEPLPPAPGSALVVAHERWEKLPASD
QSQHDAADRPATAVAIVTPDSADDPVARRLTEAVAAHPACDLTGTDEAEIAVIIAPALMQ
PDAIAAAGQLRGGAQQLDYHRAVGARCRRVWLVTICGEQVDASAPAALPAQAALAAMHRS
VGFEFPDQTFAHLDVSSRDIDEATARRCIDVLLDDHIEVAVRAHYSGTGLDCFTRTLRES
AESAAEGVATAALDHVVITGGNGTIGLRYARHCVEHGARRVTLLSRNGVDQAELDRLTAG
YPAQVLAPACDITDPDALAAVAGEYAGDGASLLIHAAGAARFAPHDQLGDHEWADVFSAK
VTGLVRMTDAWPLRPDARILLCSSVSGVWGGYGHAGYAASNRMLDTVAAQLRGNGLNCMS
VRWGLWRGTTIAAADDVARIERSGLIAMDPDTAVTTSLGCRQGDPLILAADFDRLRVFFE
SQGAAMPFATATTEGDDDSAAEGQRPDQRPISELVRAEIAAAFSLDGPAAVDLNVALVDL
GADSMLALDLRDRLRRWTGKSVPAARLLGGITGAELIAILQSDPSADGPAASPEPTAEPG
STANPVRRERLRSSRD
>A0A8D4BDZ7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces pratensis (strain ATCC 33331 / IAF-45CD)|TrEMBL
MDTSVEQIVEALREAMLENERLRRANDRISEAAHEPVAVVAMSCRYPGGVSTPEQLWQLV
DAGVDAVGDFPADRDWDVDAIYDPDPDAPGRTHVREGGFLHDAPRFDPGFFGISPREAVA
MDPQQRLLLETAWEAFERAGIDPHTLRGSRTGIYAGVMYHDYGSWLTEVPEGVEGYLGNG
NLGSVASGRVSYTLGLEGPAVTIDTACSSSLVALHLAVQALRTGECGLALAGGVTVMSTP
DTFIDFSRQRGLALDGRCKSFAEGADGTGWGEGVGMLLLERLSDARRHGHKVLAVVRGTA
VNQDGASNGLTAPNGPSQQRVIRAALADARLEPRQVHAVEAHGTGTPLGDPIEAQALLAT
YGQDRAEPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGRLPRTLHAGQPTSQVDWEAG
AVELLAEPREWPAPGELRRAAVSSFGISGTNAHVIVEAAPDPEPREKEPVWDRPLPLVLS
ARDEPGLAAQARRLLDHLATGTDPVPDVAHTLATSRAALDRRAVVVGADAATVTAGLTAL
AESDPASGVVRGAPAGESRIAFVFPGQGSQWAGMAADLLDTSEVFAASLADCAEALAPFT
DWDLLATVRERRPLERVDVVQPALWAIMVSLAEVWRAHGVRPAAVIGHSQGEIAAACVAG
ALSLSDGARVVALRSRAIAEALSGLGGGMMSVALPESRARELVAAHDGRVSVAAVNGASS
VVLSGDSDVLDALRATIVADGGRAKRLPVDYASHCAHVESIRERLLTDLADVRPRAADVP
FYSTVTNGVLDTTTLDAGYWYTNLRQGVLFEPTTRTLLGAGYGVFVECSPHPVLLNSIEE
TADAAGTDVTGLGSLRRDDGGADRLLTSLGEAFVAGVPVDWSPVFAGMPVRTADLPTYAF
QRERYWLGRSAATGDVTAAGLRSAGHPLLGAAVPVAGGGTLFTGRLSLSTTPWLADHAVS
GTTLLPGTALVELALSAGHELGCGHVTELTLQAPLPLPERGAVQLQLHVAAADGQGHRAV
TVHSRPESADEAAWTLNASGLLAPQSARPAFDLAAWPPPGAQPVPVDGAYAELAVLGYEY
GPAFQGLRAVWRRGDETYADVELPTEAGGFALHPALFDAALHADGLGAHGQETARLPFAW
TGVSLYAAGATALRVRLRGGDTLSLELADPTGAPVAAVEALVSRPADSGASASPVRADDL
YRLDWPVVPVPDAAAPAHAVLAEGGTAALAPLPEWVVLPVTGGDDPAASVREATVQALTA
LHDWLADDRTATARLLVLTAGAVTTGEEDGPLDLPGAAVWGLVRAAQGEHPDRIVLVDTA
PGAVDGEDRIAAAVRAAATSGEPQLALRGDTVRVPRLARAVVRGSAAALDPDGTVLITGG
TGVLGAVVARHLATAHGVRRLVLAGRSGTSADDFADLAESGVQVVVARCDAAERDELAAL
LAEVPAAHPLTAVVHLAGVLDDGLVTDQTPERLDAVLRPKADAAWNLHELTRDADLAAFV
LFSSAAGTVDGAGQSGYAAANAFLDALAAHRGSLGLPALSLAWGFWEQRTGMTAHLTDAD
VARMTRAGVRPLPTEEGLRLFDAALAADERLLLPIGLDLRALRGADGVPALLRGLVPAPA
RRAAATRTAGDSFTDRLAALGAAERDAELMELIRTQVAAVLGHGSDMVLDPRRSFREAGF
DSLTAVELRNRLGGAVGLRLPATLVFDHPDADALVRYLRTELLGADAGDAPGAAAPETAY
AADEPVAIVGMACRYPGGVTTPEEFWRLLADGGNGMGDFPDDRGWDLDTLYDPEPGKPGH
CSTRSGGFLYDAAEFDHDFFGIGPREALAMDPQQRLLLETSWEALERAGIDPHSVRGSRT
GVFAGVMYHDYGSRLRDVPEAVRDYLGNGSLASVVSGRVAYALGLEGPALTVDTACSSSL
VALHLAAQALRRGECTLAMAGGVSVMSTVDTFVDFSRQRNLAADGRVKSFADAADGTALS
EGAGVLVLERLSDARRLGHRVWAVVRGSAVNQDGASNGLTAPNGPSQQRVLGQALVSAGV
SAADVDVVEAHGTGTELGDPIEAQALLAVYGQGRSEDRPLWLGSVKSNIGHTQAAAGVAG
VMKMVLALGEGVLPRSLYAGVPSRKVEWGAGRVRLLDVEREWVRGERVRRAGVSSFGISG
TNAHVILEEAPDDDTSPRTEAETLSPLLPVVVSGATPEALAAQAGRLRAVADERIADLAH
SLATGRADLTHRGAIVARDRDELLAGLTALADGATTDHVVRGRPVAGRTAFLFTGQGAQR
TGMGRGLYDTHPAFRRALDEVCDALDAHLDRPLREVMWAEPGTDAAESLDHTLYTQSALF
AVETALYRLLEAYGIRPDRLAGHSIGELTAAHVAGVWDLADAARLVTARGRLMQALPPGG
AMLAVDAAEDEVLPHLGPDVSLAAVNGPRAVVVSGTRAAVDAVAAAFADRRTKRLRVSHA
FHSPLMEPMLAEFEKAARELRYAAPAIPVVTGTHATEDELCAPEYWVRHVREAVRFGDAV
RALEDDGVRTFLELGPDAVLSAMGPHALADPERSAFVPALHRDRVEEVTFAALVATAHVR
GLTADWQRMHEGTDARRVDLPTYAFQRQRLWLDDGPGAVADAGGLGQSPAGHPMLGAALT
LAGADTVALTGRLSLATHPWLADHAVAGVVLVPGSAFVELALQAGDRAGSAHLEEITLER
PLVLPPRGFVHLQVTAAAPDAAGRRQLTVHARPEDASGDWTRHATGVLAPPAAPEPAPLD
VWPPEGAVPVEVGGLYDHLAEQGYGYGPLFRCLRAAWRLGDEVCAELVLPDADAADGFGL
HPALLDSALHAIDLLDGQDPTVMTLPFAWEGVTLHATGATALRLRLTPHGSDHMTLGLYD
VSGAPVAEAASLRVRQVTAEQLNAAAPAPGDLFALRWTPAEVTADGAASEPRTLTVTLDD
TADGDLPARARGAAVRTLAALQEHLAEPADGTPLVVVTRSAVAVTADAAPDPAQAVVWGM
VRSAAVEHPGRFVLADTDGDDASAAVLPAAVATGAPELALRRGAVYAPELTRIDGSTAAP
AVPLDPEGTVLITGGTGSLGRLLARHLAEHHGVRHLLLAGRSGRTPDAEGWEEPVAPGAR
ITVAACDTTDRAALAELLASVPEAHPLTAVVHAAGVLDDGLLTDLTATRTEAVMRPKTDA
AWHLHELTRDLDLAAFVLFSSAAGTLGAAGQANYAAGNAFLDALAARRNAEGLPALSLGW
GLWDTGDGMAAGLGEAELRRLARDGILPLPADRALALFDRALTTGGPSLLPIRVQVTEDA
PALVRALEPAPAPARRAVRAVEAAPEETEPLARRLAGLGAADGRRLLVDTVCGHVADVLG
HGSGGAVDAERPLGDLGVDSLAALELRNRLGAETGLRLSTTLTFDYPTSEALAQYLFEEM
GGAGTDEELVDVEAEVVRLETLLGTVLGSDGLDDERRARVAVRLRALTARWDGSAQVTDP
GKAGDTGEKGLEAATADELFGILDGELGSFG
>H0TQ35|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Bradyrhizobium sp. STM 3843|TrEMBL
MSKLIAIVASVKAVAFLAAIGVARGEMLPVILISALFNLTQIGRGPAGLIPARETLVVRR
GLSDQSN
>A0A100JUB7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces scabiei|TrEMBL
MTDGTLNDDKLRDYLKRVAADLHRTRRRLQEVEAQQQEPVAIVGMGCRYPGGVDSPEKLW
QLVASGTDAVDAFPADRGWDLGALYDPTRERPGTTYSAEGGFLTGAADFDPGFFGISPRE
ALAMDPQQRLLLETTWEAFERAGLDPGALRGSDTGVFVGVMYQDYGLRLRQVPDDIQGYI
GNGNSDSVASGRLSYTFGLEGPAVTVDTACSSSLVALHLAAQALRRGECGLALAGGAMVM
STPVPFVEMSRQGGLAADGRCKSFAAGADGTGWGEGVGMLLLERLSDARRNGHPVLALVR
GTAVNQDGASSRLTAPNGPAQQRVIRRALADAGLTPADVDVVEAHGTGTPLGDPIEAQAL
LATYGQDRPADRPLLLGSLKSNMGHTQAAAGVGGVIKMVMAMSRGVVPPTLHVERPTPTV
DWSSGAVELVTEAVPWPETGTPRRASVSSFGISGTNGHVVLEQAGPEPESESAPAPGTEP
GTTDELSATDGPGLPTALPWPVSARSREALRAQARRLAAHLDTYPGQRPLDIGHALATTR
AALEHRAVVVAADEEGFLRGLRALAEDTPEPGLLRGTGVPGADTAFVFPGQGSQWTGMAA
ELLDTAPVFAERIADCARALAPHTDWSLTDVLRDAPGTPPLDRVDVVQPALWAVMVSLAA
LWRSYGVEPSAVAGHSQGEIAAAVVAGALSLEDGAKVVALRSKAIVTLAGAGGMASVPLP
VDEVRDLLTAWDGRLSVAAVNGPASVVVSGDRAALDDLIDRLTARDLRVRRIPVDYASHS
AHVERIHDELLRLLADITPRPSDIPFYSTVTAEPLDTTGLDAGYWYRNLRRTVEFEQTTR
ALLAAGHHVLVEVSPHPVLTVPMEETARAAGADEAVVTGTLRRDDGGRARFLAAVGELYV
HGVRVDWRAAYAAWRTRRADLPTYAFQRRRYWLEDSAAPQGDMASAGLAAADHPLLGAVV
ALADGDGLLLTGRLSTRTHPWLADHAVRDAALLPGTAFLELAVRAGDQVGCGQVEELTLE
APLVLPPEGGVAVQLAVGAPDRDGRRPLSLHARPDGTDDLPWTCHARGLLGPATEEAAPA
DPAVWPPAGAVPVDLDGLYERFAEGGFAYGPAFQGLRVAWRLGEEVFAEASLPSELQAEA
ARFGLHPALLDGALHATGLGEAAEGRMPFVWTGAVLHAQGATGLRMRITPAGPDTVTLRA
LDQAGRPVLTVAGLALRPVGAGNFTAPAAGRHHDSLFRLDWTPVRPVPGPTTPSWAVLGP
TEDTPGAAHHADLAALRDADGPLPEYVLADLGAAPEVQADGLADTTRTAVHDALALVQDW
LADDRFTGARLVLVTRGAIAARPGEDVPNLPHSAVWGLVRSAQTEHPDRLHLVDLDPDAD
LPAALAAVLTATGETQFAVRGSEVLVPRLARIPVQDDDAAPPLDPDGTVLITGGTGLLGA
RVARHLVTGHGVRHLLLTSRGGPDAPGAAELCDELAALGAEVSVVACDAADAERLAEVLA
GVRHPLTAVVHAAGVLDDGVVSSLTPERVDAVLRPKVDAAWNLHELTEDMDLSAFVLFSS
AAGTFGGPGQGNYAAANAFLDALAHHRRARGLAGRSVAWTLWERRSAMTGHLGDDEVRRI
ARSGLPPLTDAQGLALLDSALTVDEPLLVALRLDTAALRARAESEPVPRLLHGVVRLPAR
RQAAPASATDGDGDRGPLAERLAALDASGRRRELLDLVRGQVAAVLGHPSPEAVEAGRAF
RDLGFDSLAAVDLRNRLGNATGLRLPATLVFDHPTPEVLAAHLGGELLGADTGRVPTAVP
AAGGGGAATDEDPIAVVAMGCRYPGGVRSPEDLWNLVSSGSDGIAAFPADRGWDLDALYD
PDSERHGTSYAREGGFLYDAAEFDAGFFGISPREALAMDPQQRLLLETSWETLERAGIDP
VTLRSTATGVFVGVMHQDYAARLLPHIPEEVEGFLGAGNSGSVVSGRVAYALGLEGPAVT
VDTACSSSLVALHLATRALRSGECSLALAGGVTVMSSPELFVEFSRQRGLASDGRSKPFA
AAADGVGFGEGVGMVLLERLSDARRNGHRVLALVRGSAVNQDGASNGLTAPNGPSQQRVI
RAALADARLAPGDVDVVEAHGTGTRLGDPIEAQAVLATYGQDREQPLWLGSLKSNIGHTS
AAAGVGGVIKMVEAMRHGVLPRTLHVDAPTPQVDWSAGAVELLTEERSWPAGPDRPRRAG
VSSFGMSGTNAHLVLEHVDEDVAESSPTEGPAVPWVLSGHTPEALRAQAERLAGHADAHP
GQGAAAIGQALATTRSRHDHRAVLVGDREQLTAGLRALAADAPLATLARGTATAVGRTVF
VFPGQGAQWTGMALDLLDSSPVFAARMAACERALAPHVDWSLTGVLASATDLERVDVVQP
ALWAVMVSLAETWRSCGVEPDAVLGHSQGEIAAAVVAGALTLEDGAKVVALRSRLLRAVA
GHGGMASVALPADRTRELLAGWGEKISVAAVNGPRSTVVAGETMALAELLASCEKDGVRA
RRIEVDYASHSAGMDPLRAELLDVLADITPATAGTRMFSTLEADWIEGPELTADYWFRNL
RGTVEFEPAVRELAGAGFTTFVESSPHPVLAPAVQEVLEDGAVTGVVVGSLRRDDGGRDR
LLLSLGEAHVQGVPVDWPAALGRTSRPVDLPTYAFQRTRYWLDAPVRTGDVAAAGLGATD
HPLLGACVDLADTGERVLTGRLSSRTHPWLADHVVSGTNLLPGTAFLELALRAADEAGSA
LVDELTLQAPLILPERDAVHVQLRLGPPDDSGRRNLGLYSRAETDPGADWTPHATGTLAP
GDGADGPSAPAAWPPAGTEPVDLEGVYDRFAEAGYRYGPAFQGLRAAWCDGTDVYAEVAL
ERQSDSGGYLVHPALLDGALQASALLGDRPGPARLPFSWNGVTAHATGAAALRVRIGPAG
PDTVSLDAWDPTGQPVLSAESLVLRPLSPDLLAAAVAGRDGLYRLDWTPAPGAGATAPLT
GWAGLDDTGSGAQPTAVVWTCPTATGPDEAARVRDTATATLAVVQRWPSDPRSGDAPLVV
VTRHAVATGPGGHPAYPAQAAAWGLVRAAQTEHPDRFVLLDLDDTDESADALPHLLGLAL
ATREPQLAARAGNPLVPRLARAGRPGTLTPPAGEAVWRLDTTGEGSLDALALVPSPEAAA
PLAPGEVRVAVRAAGLNFRDIAVCLGLAPDQRILGSEGAGTVLETGPGVTDLAPGDRVFG
VFGGAFGPVAVADRRTLAPIPPGWSYARAATVPIAFLTAHYGLFDLGGLKAGETVVVHSA
AGGVGMAAVQLARHAGAEVYGTASPGKWDVLRGLGLDDDHIASSRTLDFADRFLEATGGR
GADVVLDCLAREFVDASLRLLPRGGRFLEMGKTDIRDADTVAAAHPGVRYRAYDLAEAGP
ERIARTLDLILDLFRQGTLTPLPLTCWDVRRAPEAFRYVGQARHTGKNVLLPPVAPNPDG
TALITGGTGTLGRLVARHLVTEHGMRRLLLTSRSGPDAPGAAELCDELAALGAEVSVVAC
DAADRDRLAEVLAGIPAEHPLTFVVHAAGVLDDAVVSSLTTEQLERVLRPKTDAAVNLDE
LTRDHDLAAFVLFSSAAALLGGGGQANYAAANAALDALAERRRAEGLPGLSIGWGMWEER
SGMTGHLGDVDLRRMSRSGVTPLTSEEGLALFDAALRSEDAYLLAARLDTGALRAGGGQD
VPALLGGLVRAPRRRAAANGDGGGRAAGLADRLAGLSEADAHAALLDLVRGHAAAVLGHP
SPELVQPTRAFKELGFDSLTGVELRNRLSSATGVRLPAGMVFDHPTPDVLARHLAATTGR
PRPAKASAPLAELDRFAELVAGLAPDAPDRDRLSQRLREVLARLEATEPAGQVTADHIES
ASHDEIFDLIDNQLGIS
>A0A117EFM0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces scabiei|TrEMBL
MSTDKVVEALRASLLENERLRGENTRLRDESREPVAIVAMSCRFPGGVRTPEDLWRLLAE
ERDAVSEFPADRGWDAAALYDPDPDTPGTSYTREGGFLHDACGFDAGFFGISPREALAMD
PQQRLLLETCWEAVERGGIDPLSLRGSRTGVYAGVMYNEYGARLQRIPEDVEAFIGTGTV
PSVVTGRIAYTLGLEGPAVTIDTACSSSLVALHLACQALRAGEISLALAGGVTVMSTPSL
YVGFSRQRGLAPDGRSKSFAAAADGAGFGEGVGMLLLERLSDARRNGHPVLALVRGSAVN
QDGASNGMTAPNGPSQQRVIQQALAAAGLSPAEVDAVEAHGTGTRLGDPIEAQALLATYG
QGRPADRPLLLGSLKSNLTHTQAAAGVGGVMKMVLAMRHGLLPRTLHLDRPTPQVDWTEG
NIALLTEATPWPETDHPRRAGVSSFGASGTNAHTVLEAAPADVPAEDESRDEIPGPVAWA
LSAKGEAALRGQAAALHAHLTGTPQAHPLDVGFSLATTRSGFADRAVVVGDDRPALLSGL
AALAAGRPDPAVVSARARPGRKAVFVFPGLGSQWPGMAAGLLDESPAFAAGMADCAQALA
PHIDWSVTDVLRGAPGAPSLDRVDVLQPVLFSVMVSLAALWRSYGVEPAAVVGHSQGEVA
AACVAGALTLEDGARVVALRSRALAGLAGGGGMATVVLSAAELGPYLERRSGKVTVAAVN
GPRVLVVAGPGDEVGALVDELSAEGVMAWRIPVDYASHSDDVSTVRDRLREDLSSLVPKA
PAVPLVSTVDADWIGAGDLTHEYWYRNLRQTVRFHDAIRLLLDAGHRTFVEVSPHPLLTY
GIGDTAADAGADDAVVLGTLRRDEGGPHRMLLALGEAHANGVVVDWRRVFDGTGARLTDL
PTYAFQRTHYWLDVPAHAGDPRSAGQTETGHPLLTAAVDLPDGDGVLFTGRLSPRTHPWL
ADHAVSGTVLLPGVAFVEMAAHAAVHVGCTAVEELTLAAPLVLAADEARRLRLTVDAPDP
EGRRAVALYSRPDDPESTEPWVRHAGGTLAGTSASAPGDPGRWPPGDGAERLDLDHLYAD
FEAAGVHYGPLFQGLRAAWRVGDEIHAEVALPESVPGTRESGFAVHPALLDAALQTVALR
PDSTRDTDARTGGVPLPFSWHDVTIAPTADPVLRVVLSPAPQGGDAVSVRITDRTGRPVV
TVGALSLRAAAGAPAAAERSLFRLDWTRLPGTGPATGTWATLGSSGGGLLPAGFRADPCP
DLADVPPTSDAVLALCPPAEGAGPEAARAAVGAVLDLLQRWLAEPKFSETPLVLLTRGAV
DLDGAPADLGSAAAWGLLRTAQLEHPGRLVLLDTDGGDGLEAALATALAEGEPQLALRDG
TLYAPRLVRPPVADRPAGFGPEGTVLVTGGGGTLGGLVARHLVTTQGVRRLLLLGRRGAA
AEGMAALTEELSAAGAEVTVAACDVADREALAGCLAAIPPEHPLRAVVHTAGVLDDGLVT
ALTPERLSAVLRPKADGAWNLHELTRDHDLTAFVLFSSSAGVFGSPGQSAYAAANAFTDA
LAAARHRAGLPGTSLAWGLWEQRTGLTDGLGDTDLRRMARSGVRALPTEEGLELFDAALA
GDDPVLVPVGLDLRARPGGPVPHLLRSLVRTPAARRRGPKPEASLRPRLAAAPEAEQGEI
LLRLVRTQAAEVLGHTDPDALSEGDAFLESGFDSLTAVELRNRLAAALDLRLRPTAVLDS
GTPARLAEHLRGELTRSTAPGAGRQAGEPPHDAVSALFRQACEVGRIHEGIQILQQAAKL
RPDFGSGPELLSSSGRRPELLRLHVRDDAPELVCFASVVALGGAHQYSRFASAFEGRYGV
SALDAPGFAPDEPLPAGMSALLDFQTEVLLRRLGDRPKVLLGSSSGGTLAHAAAARLEAL
GAGPAAVVLLDTYLSGDRAMTQFDDVLVSGMFEREDRAAPMDGTRLTAMGRYFQLLDDWA
PPPVAAPVLLVRASSPLAEPAPDSDIDWRASWPSAHSVLDVPGNHWSMMEQHLRTTVDAV
TGWLDSVIS
>A0A0L6JLI0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933|TrEMBL
MKYYYPQERVAVVALGCILPDAMNKETLWKNILEKRISIKEIPDYYFNKSVFYRPEAKGK
INKEDKTYTKIAAVIDEFNFLDLGRKYRIPPAVSAYMDNNQKTAIYCVDQAIETMKSSLP
KDRTAVILCNGAPGDKFENLVRRTFFANVESHILNHPEVSKEKLTEIQQVLKDVSDDILK
NTQPVIEDTAPGYLQNIIAGRISNILDLWGPSYVIDAACASSLTAIAAGVSGLLNNEYDA
VVTGGVEVTLSEIGLVSFSGINALSPDGSYPFDSRANGFVMGLGGGAIVLKRLSDALRDG
DHIYSIISGYGQGSDGKGKYIAAPSEEGQIRVIKSACKMADYSVDTIEMIEAHGTGTIVG
DVVETSALKKAFAGLGAQKENNCGLGSIKSNIGHLKNAAGIAGLIKATLALENKILPASA
NIVEINPKLQLEGSPFYVLQDNKKWIENSQHPRRANISAYGFGGADYHICLEEFRPEFLQ
KSYSFNNINKYKNNENNTADKEEAILFSGDSIEAVIDEYKSFIEKCEESEDYFEKTVYLN
NISASCKHGWRISICASSLYQLKDKWKLVEQYIREDRLNEANLLNLKGIYVGNGPEVPSS
QIAVMFPGQGSQYPNMLRGLYETYPGVKAFYMKADAIWESKYNSPITSLVFGNDDEQLKD
KLKNTKNTHPAMFISNMGVYKLLCEAGIKADYMIGHSLGEITSLFAGEMIDLKSTVNIIG
ERGYSFDRIDENKRGRMLSIKEKADKVGEIIKSSGFGVSIANINSMDQTVVGGESKEIEK
FSEYLNQNGYKTTLLNVSHAFHTSMVSKAADSFYESIKEIKFNNPKFKMVACHLTELYND
LSTGTDDMAAVLKEQILSPVRFAESILMLYDKGVRVFIESGPSNVLTNLVKNILSDKDVK
VININNKSKCPVEGFKQALAMLFAHGVELNYVPSNNVLGLHEENVSTVVYKVEAQAAEIP
HMDKIKVPSKNESQGLISTNVDSTISDITDTLHKNYGYIGINPGESLVYSGVSMGLPGTF
KKAFTDDNFQYIVDGKNMIELLTDEEAESILDLNITRLIKSEKDSVLKKITTINEVIHLL
GKMGKMDMINDYLIDEKVLNEMTQSVCAGVAAGYEALKDAGIPLVREFRKTASGSMLPGR
LVLPEELQDGTGIIFASAHSQVESVISEVSKYTAAKFGSSARKDILMFFEAVISKVSDYE
SKKILSDWFALHYSRLSNNPSEADVYEFNHNFLALLSSQANNRLAQFIGATGPNMYISAA
CSSTASAVTVAEDLIRAGHAKRMIIIGADISSGKNMLPWFAAAFSSIGALTDSDSLYDAA
VPFDNRRNGMILGSGAVGLVIEKDSDVAKRGMNGICRILGTHLFNAAGHQTRIDVKRHCI
ELDKFISKMESEYNLNRNALASKMVYCSHETYSRRQSGCSNMEKVALENTFGDKFKEIKV
INTKGMTGHTLGASIEEAVSAKVLQYQKLPPIVNYKEPDPDLEGLNLSKGGNYEVEYVLR
TVSAFGGNGNYHLLQRIANGDERIVNSKAYREWIERISSKDAELKNNGRLIIAEVQSGNE
LVDKGKVDLAEENIVDATDKVKSAAANKPTADKATPNKATANATPARENPEKIKDEVLEI
YAYITKYPKEMLEPSMELEADLGIDTVKQATIFSILSEKFKLVLSEGQALSNYPTIGHII
ELVLEKACNNNGNLKSQFASNEEELPSRKLKVEPAMKELAFEDCEAEVLKLVSEITLYPV
ELLDKEMEMEADLGIDTVKQATIFSILRERFEIVGESSENLSIYNTIGALIEFVRGNSKK
SEGKGKISTKPLREIKGVQDTKIIRGNNDNNVKQEIKDGNNIAIEILNLISEITQYPVDM
LEDDMELEADLGIDTIKQATIFSELSQKFNLDAKVKLNTSELNNIRSLINMVKSNVLSID
SPISLQSGKSQNDADNSNSSDITKEEAKEFTADDNHELELCVQYPMVVSENIGNKDYDLK
DKNIMVIGDNSKTVGLISEHFKKVSSGVSGFVFEKCINSEELEEKIGNYKDAIKSTDVII
DCGHLGEVYEFKKLTYETEKEILHLNSLTRFIFYKKFSQIRPDTALRILCTVFVDGCFGF
VSDENSKGDPYYGALSGFYKGLRKELGKSKVKIVDLGGESGLILNDGVLDRIHNELEECS
SLYEVGYIDNKRVTLKLDNVERSEMMPVEKFDSNHFVITGGGNGITAGIALGISKHIKAK
LTILGRTALPSNIEELSNLDQNALEQKKHEIYDQLKREGKKATPTEVQKEHNKLIKALSV
YNLINDIKKNGCQVRYFSCDIREHESLKAVLNGAIADFGPVNVVVHGAGVEKSRLLGQKT
KEEFEEVFEVKANGLCNLYRLIDKKHLKVLIAFSSISGRFGNEAQLDYCSANNFLSSFMS
MVKSQNKKIRAVSISWSGWKDLGMAWRNEFVKENAEEMGLHLIEPERGVNEFINILTSNI
NLDEIVISKGLSFFVGLKKWHGIKNAVSLIDWVSKKEGEIKRIYKVLSVKSDPIINHHRV
GKTPLMPAVGFMEMCAQAHSLIFEKKDQYCFKNLVFNNALKLFNEKPQEVIMKPEKSSNG
FMKATFYNYFKPKIGEGKLVELNSMNVSPMIGDYEYLNELKEIETDNMEEILLKNSLEQL
SKTLPNSINLGPLFMDEKASKINMFKYNDQGVVLSIALSEEQINNKKYNLDNLLINPAFA
DSLMQCCGIHSSVDTDGLYLPWQVEEFGIVNTPKESGLYKAYAKRISGNDSEKSYDVILY
NDKGEVCYYAKRVTVKRIAQ
>A0A378WZ94|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia africana|TrEMBL
MRSACVFPGQGAYLEDTFLVWADRWPQIGRTFREIDDGIASLGGAATVPMLLGGDPPSLN
DLLADDPDVLQLALFGTAVAAYRIVASTRLRPDVLIGHSFGEIAALVAAGVFTVGQGARI
VHIRSRCLRAAAGTGGMLVLRTEPRGAQALVDSIEVAELVVAVENGPRQTVVAGPAEALR
TAEQTARANGVPAARISSPYPFHSPLLEPVAAEFTRRLRAELATTGRCLRPVYSPIMQRF
YTDDDDFAAILARHLVLPVRFTGGLRYLGDRGVRTFIECGARDALTGIVRATLPGINASP
TIVRGGRPASAGPAAPADRQGESSRPSSAARTPI
>A0A0N1GBY6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MNDSRMRHLLERVTAELHDTRRKLREAEDGEREPVAIVGMGCHFPGGIDSPEDLWRLLAE
GGDVVGDFPDDRGWDTATLFDPDPDRPGTSSTRRGAFLAEPGAFDPDFFGISPREALAMD
PQHRLLLETAWETFERAGIRPDALRGSGTGVFVGSNGNDYAPRTGAVPQDLEGYVLAGNA
ASVASGRISYTFGFEGPAVTVDTACSASSVAVHLAVRSLRSGECDLALAGGVTVMTTPST
FVEFSRQHGLSTDGRCKAFAAAADGTGWSEGVGLLLVERLSDARRLGHRVLAVIRGTAAN
QDGASHGLTAPNGTAQQRVIRQALSDARLTAAEVDAVEAHGTGTTLGDPIEAQALLAAYG
QERAHGRPLWLGSVKSNLAHTQAAAGVAGVIKMVQAMRYGVLPKTLHVDEPSPHVDWASG
AVSLLAEHRPWPETGQPRRAGVSAFGMSGTNTHIVLEQAPEPVTAADEAGSDASGPATAP
PPGATVLPLVLSARTPAALAGQAAALAAHLRSGTGSDTGPGLAATAFELVAGRAAFEERA
VVVGADEDTLLAGLDALAAGEPAPGLVRGTAGTDPRTVFVFPGQGSQWTGMARELLDTSP
VFADSVAVCARALEPHTDWSLTAVLRGAEDAPGYDRVDVVQPTLWAVMVSLARLWQSYGV
RPDAVVGHSQGEIAAAHIAGALSLDDAARVVALRSRALGALSGDGGMVSLALPVEQATDR
IAPWAGRIALATVNGPAAVVVAGEPAALDELVAACEREGTRARRISVDYASHSPQVERIR
EELLDVLAPITPRAARIPLLSTVTGDWLDTTRMDAGYWYTNLRQTVLFEPAIRKLVAEGH
DVFVEAGPHPVLTAAVQETAEAAEPARPVTVTGSLRRDEGGLVRFLTSVAETQVHGVEVD
WSPVLTGPRPPVADLPTYPFQRRRFWLEPATGRAADASGLGLRPAGHPLLGATLRPAEGD
GLLLTGRLSVQAQPWLADHTVLDRILVPGTALVELTVRAADEAGWDTVDELVIETPLVLS
ATEAVQVQVSVAAPDEQNRRAVTLHSRPADAPDDSPWTRHTTGFLTRPAAPDRTAPLPDS
WPPPQASALSLDGLYDRLAASGVVYGPRFQGLRAAWRHGTEIYADVALDGEERAAAGEFG
VHPALLDAAFHAAGLDNTLRAEPGEALLPFAWRGIRLHASGATALRIRLAPTADGGLSLD
AFDTAGAPVLSVASLVYRPVSAARLAAGSGAVVPLYGLGWRALPLPTGTPSAATAVLRPG
TDPGSAPLEGAVFDSPAAVAEAVRAGVGVLDLVRYEVSGQEVNGPEANGTPAQAPDEPVP
VLARATLERVLALVQDWLARPELDAVRLAVVTTGAVSVAGESPDLTTAGVWGLLRSAQSE
HPGRLLLVDVDGTGRADSLAAAAAVGESQLALRDGTAFVPRLLPAPAAPSRTWRFAPAEG
TVLVTGGLGLLGRLVARRLVTDLGVRHLLLTGRRGARTPGAAEFLAELADLGAHVTVEAV
DAADRDALRVLLDSVPAEHPLTGVIHAAGVLDDGVLAALTPDRLDTVLRPKADAAWNLHE
LTRDAQLSEFVLFSSAAGVLGVPGQANYAAANTFLDALVAHRRSRGLAATSLAWGLWEER
GELTGHLDGADHRRNARHGTRPLTTPEGLALFDAAGATDHALLVPLALRHGADPAQLPPV
LRDLVRTRRPTARTADVPTGATLAGRLLSLDAAAREELLIGLVRAEASTVLGRDDREGIA
TDRAFKDLGLDSLTAVELRNRLGAASGLRLSPTLVFDHPTPRSLARFLLAELVGGQPETQ
APVFPAATTDDPVVIVGMGCRLPGGVASPEDLWDLVSSGVDAITPWPTDRGWDTDGLYDP
DPDQPGRTYTQHGGFLHDAADFDAGFFGISPREALATDPQQRLLLETSWEAFERAGIAPG
TLRGSRTGVFVGVMYNDYAARLHDLPPELEGYLTNGSAASVASGRISYTYGFEGPAVTVD
TACSSSLVALHLAVAALRAGECDLALAGGVAIMSSPSGMVAMARHRAFSPDGRAKAYAAS
ADGTGWAEGVGLLLVERLSDARRHGHPVLAVVRGSAVNQDGASNGLTAP
>A0A0N0MW65|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MGLELAAAFPVFADALDAVCAVVDPLLGRSLREVLTEESGVLDRTGLTQPALFAVEVALF
RLVESLGVRPDVLIGHSVGELAAAHLAGVLSLEDASRLVVARGRLMEALPSGGVMVAVQA
SEAEVLPLLTDPRVSLAAVNGPEAVVIAGAEDAVQAVVEQLPGRVRRLRVSHAFHSPLME
PMLAEFREVAESVRYGVPRIPVVSNVSGRIAEGDELSSPGYWVEHVRRPVRFLDGIRTLS
DLGVSRILELGPGGVLTAMARECLPPDNGMLLVPSLRKDRPEPESMVAALAGLFTDGVDV
DWSPLVAGGRVTPLPTYAFQHQRYWLEPRGKAVGASDLGLTAADHPLLGAAVGLAGGGGV
VLTGRLSLKDHAWLVDGVVHGRVVVSGGTFLELALRAGDEVGCGLVAELVVDSPLVVPEQ
GAVHLQLVVAGPDDADRRAFTVHSRAADVSSDAPWHQHAHGVLAAAVGPVPDDAPVPDDA
PDLDDAPDLTVWPPAGADASDADGVWRRDGGVFAEIALPTDTNTDDVTAYGLHPALLEAV
VRAIADDQQSQGQPLVISGLRGARLLASGATALRVHLSATGALTLADHTGAPIACADEMR
TTVLTSDDLPAPAHADALFQVAWVPVPLPAAQSPAGRFAVLGADPLGLAGQLPASASDPD
TVLASFVSDFSNTTEGADGSTGVDADAAAEAAHRALATVQSWLADDDRSVGVRLVVVTRG
AVAARDGEEVADLTHAPVWGLLRSAQSEHPDRFVLVDLDGSRASLAALPAALATGEPQIA
VRAGRAYAPRLARTDPSRSTAGTVPFVPGDGTVLVTGATGGLGRLVARHLADVHGVRRLL
LVSRRGAEAPGAADLRAELAALGAEVTYAACDVADRTALAAVLAAIPAGWPLTAVVHVAG
VTDDAVTETLTDAQLDRVLRAKVHAAANLHELTDGLDLSAFVLFSAAAGLLGGPGQANYA
AANAFLDALAHRRRATGLPAVSLAWGLWAETGGMGGRLSETDVRRMARGGVLPLSAEQGL
ELLDTALGIDEPLLVPIRLDTTVRPDTTAHEVPALLRGLVRAPVRRAAQQPRTADAGGSG
SDSGKSYAERLAELPVVERGRVLLELVRSQAAAVLGHADAGAVGAEQAFREIGFDSLTAV
ELRNQLNTVTGLRLSATLVFDYPTPDALARHLNTELLGEDEDGRADDRTPVRTAAAVDEP
IAIVGMSCRFPGGVASPDDLWRLLRAGEHAVSEFPSDRGWDVEDLYDPDPDRPGKTYVRQ
GAFLRDVGAFDAGFFGISPREALAMDPQQRLLLEATWEAFENAGIDPASLRGSQTGVFAG
TNGLHYTSRVTKVPQNVAGYLVTGNSASVVSGRISYTFGLEGPAVTVDTACSSSLVALHL
ASQALRQGECTLALASGVTVMSTPGFFLEFSRQRGLAADGRCKAFSAEADGMGASEGVGV
LVLERLSDARRNGHEILAVVRGSAVNQDGASNGLTAPNGPSQERVIRQALVNAGVSAVEV
DVVEAHGTGTRLGDPIEAQALLATYGQGRSEERPLWLGSVKSNIGHTQAAAGVAGVMKMV
LALQHGVLPRTLHVDEPSGQVDWSVGAVSLLTEEQAWEADGHPRRAGVSSFGISGTNAHV
IVEQAPDPVVEEPSVQGPVSPVVPLVVSARGEGALREVAGRLVPVVGDGGVGVVDAAFSL
VSGRAVLGHRAVVWGRDRGELTSGLEAVHRGERGAGAVVGVASSGGRLGFAFTGQGAQRP
GMGLELAAAFPVFADALDEVASVVDPLLGRSLRGVLAEESGVLDRTGVTQPALFAVEVAL
FRLVESLGVRPDVLIGHSVGELAAAHVAGVLSLEDASRLVVARGRLMEALPSGGVMVAVQ
TSEQEVLPLLTDPRVSLAAVNGPEAVVIAGAEDAVQAVVEQLTGRVRRLRVSHAFHSPLM
EPMLAEFREVAESVRYGVPRIPVVSNVSGRIAESGELSSPEYWVEHVRRPVRFLDGIRTL
TDLGVSRILELGPGGVLTAMARECLPPDNNTLLLPSLRKDRPEPESMLAALAGLFTDGVD
VDWSPLVAGGRVTPLPTYAFQRQRFWLEESSEGSGGWGLGPAVVLADGEGVVFSGGVSLR
THGWLCGHVVHGRVVVPGSAFVELVLRVGDVVGCGTVAELSVDNPLAVPERGG
>A0A0N0N0J8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
GVDPSVVVGHSQGEIAAAVVAGGLSLEDGARVVALRSKAIRAIAGRGGMVSIALPLAAVE
DLLSGWAGRVDIAAVNGPASVVVAGDADALDELMAHCEAEEVRARRIPVDYASHTWHVEA
IEGELAEVLADVAPRSGSVPFFSTTEAELVDTASLDGGYWYRNLRQRVRFAEAIESLAGQ
GYAAFVEASSHPVLGMAVQEAVPDAVVVGSLRRDQGGPDRFLTSLAEAWVRGIPVDWTAV
LSGQGARTIPLPTYAFQRRRFWLEKTAPAPVLDKAQEVDARFWEAVEREDLEALADTLRL
PESGQLANVLPALSSWRKGQAARSAVDGWRYKVVWKPVARESRPASLTGQTWLLLTPTTE
HATATATITAVTTALTTHGATVRTLELTPHHTDSATLDSALTEALAELPTPVSGVLSLLG
TDDGPLPEHPVLSTGVALTVCLLQALGRAGVEAPLWCVTQGAVAVGDEEAVANPGQAAVW
GIGRVAALELPERWGGLVDLPERIEGRDVAALCAVLAVRGDSAEDQLALRGNTTLVRRLV
PAGASGSARTAGGRSRQWAPRGTALVTGGTGALGAHIARWLARAGAEDVVLVGRRGTVDD
SAFAALEAEVAALGARLTVAACDVADREALVALLNSLREQGRCVRTVVHAAGVGILRTLN
RLGLAEFAEVAAGKVAGARHLVEVLDPAETDALIFFSSISGVWGVGRHAAYAAANATLDA
LAEHARRARGLPVLSAAWGPWDGGGMIAEDMRDPLRRRGIPVIDPEPAMVALQEALDRDD
TVVSLADVDWARFVPVFTASRPAPFIADLEPRSAPDTAVERAGGPENTEQPTLAHQLSAL
PAADRDRFVQDLVRAEAAAVLGHPSPDAVDTAYAFKELGFDSVSAVELRNRLASRTGLRI
PTTLVFDHPTPLAAAAHLRALALGDNGTTAANSASATGSSDTAVDDDPIAIVSMGCRYPG
GIASPDDLWRVVLAEEDVITGFPADRGWDTAGLYDPDPDRHGTSYVRHGGFLHDAGEFDP
GFFGISPREAAAMDPQQRLLLETSWEAFERAGIDPKTLRGSSTGVFTGLTDQNYGTLLTR
STDGTEGYLVTGASTAVASGRVSYVLGLEGPAVTIDTACSSSLVALHLAVRALRSGECAM
ALAGAAMVMADPAPFVGFSRQRGLAPDGRCKPFAEAADGFALAEGVGVLVLERLSDARRN
GHPVLAVVRGSAINQDGASNGLAAPNGPAQQRVIRAALADACLTGGDIDVVEAHGTGTRL
GDPIEAQALLATYGQERQPEQPLLIGSLKSNIGHTQTASGMAGVIKMVLAMRHGILPATL
HVDAPSSHVDWSAGAVSLVTEETQWPSGEGRVRRAGVSSFGISGTNAHVVLEEAPGVPDL
EVVGAEPVFVAGAGAGGVVPWVVSGRGAEALAGQAGQLASFVEAGSAVGPVDVAWSLAGS
RTAFENRAVVLGGESAELVAGLGVLASGEVTGARVVRGAVAGGADRVVFVFPGQGAQWVG
MGRELWDSLPVFAASMEACERALEPFVGWSLSEVVRGGAELTDVDVVQPVSWAVMVSLAA
LWRASGVGAAGGGGGSRGGSAAAVVAGGLSLEDGARVVALRSKAIRAIAGRGGMVSIALR
LAAVEDLLSGWAGRVDIAAVNGPASVVVAGDADALDELMAHCEAVEIRARRIPVDYASHT
WHVEAIEGELAEVLADVSPCSGSVPFLSTTEAGLVDTATLDGGYWYRNLRQRVRFAEAIE
RLAGQGYAAFVEASSHPVLGMAVQEAVPDAVVVGSLRRDHGGPDRFLTSLAEAWVRGIPV
DWTAVLSGQGARTIPLPTYAFQHRRYWLDFPESAPAVPGTAATDPSADDVDTRFWEAVER
EDLEALADTIELAPERRGTFGAVEPVLPVLAEWRRRRRADAMLDSWRYTVTWQPAGASAA
GASSLPSSWLVVVDEVVGGRVHELVERLRGRDGVEDVVTVVVDAVGQDRAALAERLRESL
GHNPHPGGVLNLLPLTAAAAPQPAAVPEAVVRTLLLMQALADADVDAPLWTVTAGAVAAT
GVDTAAGPVPEQAAVWGLGRVYGLDHPLRWGGLIDLPAAHGSGVSDDSAALDARTWNRFF
DALAGDADEDQFAVRADGLSVRRMVRKPVGGRDGERGRVSFSGTTLITGGTGALGAHLAR
RLAATGAEHLLLVSRSGPDAPGAEELQDDIRQLGARVTVAACDITDRDALAKLLADVPSE
LPVNAVVHAAGAEPPAVAVTDTELDAVRAEMGAKIAGAVHLDELLADRPLEAFVLFSSGA
GVWGDGGHFGYAAANAYLDAFAEWRRGRGRVATSIAWGAWAGGGMVHEAEGDRLRRYGVP
TMDPEVAVGAVQQALAHDETFLVVADVLWDRFAATYSATRRRRLFDEIPDVRSAVVLPQV
AEGAEELESEGGPQARLGRQLAGVGRAEQERTVLHLVRTQVAAVLGHEGIGAIGAGHAFR
DLGFDSLTAVELRNRLREVTGLTLPATLVFDHPTPAALGDRLLSELAPDTGELDAGQDLG
TLDGLEAAVAALDPTDDVARARITTRLQALLWRLSDTPTEKPAGGGDPADHDDELLEEVS
DDEMFDLIDKELGLN
>A0A6C0QDF7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. S4.7|TrEMBL
MSVAGQESHQDADRDGSAFADPAVNRRPIAVVGMACRLPGAGGPDDFWTLLREGRDAVGP
APEGRWPEGPLSPQDLVDAGLLSTARAGYLPRVDEFDPAFFGIPPKEAAAVDPHQRLVLE
LTWEALEEAGIVPATLDGAPIGVFVGAMEDSYAAVTRDHGPDGIGRHTATGLNRGVIANR
VSYTLGLRGPSLTVDTAQSSSLVAVHLACESLLRGESDVALAGGVNLALAGEGFLTAARF
GALSPTGACRTFDAGADGYVRGEGGVVLVLKPLDRALADGDTVHCLISSSAMNNDGSTQA
LTQPSPDAQEQVLNAAYRRAGLTAAEVQYVELHGTGTRLGDPIEAAALGAFAGSLRGSED
PLLVGSVKTNVGHLEGAAGITGLLKTILAVRHRQLPASLHFTEANPRIPLDELRLQLVRE
TRSWPHPDRQLTAGVSSFGMGGTNCHVVLREYAADTTAATTEDVAPAAQSTAAQTNGAET
TGARSTGASTTGPLPYVLSARSEPALRDQATRLADFLAEQPAHRLTDVAHSLAVHRSAFE
QRAVLFAPDRGTLITHLTELAEGRTPGGAARGTSLRGGTAFLFAGQGSQRPGMGLQLADA
FPAFRAAFDSVCAEFDRHLEVPLRRVIAAPDGTPEAALLHRTAYTQPALFAYETAAFRLL
ESWGVRPDYLLGHSIGEIAAAHTAGVLSLTDACTLVAARARLMQELPAGGAMVAIEATEA
ELVTEAEETGETGRVAVAAVNGPNATVIAGDEEPVLAVAARWHAKGRRTKQLRVSHAFHS
ARMDGMLDAFREVAESLTFHAPDIPVVSNLTGQLADPDELRTADYWVRHARHTVRFADGM
ERLSELDVTTFVELGPDATLTTMARGCVDDPEPAFVPLSRRDGRSEADDVLAAVATAYTH
GVAVDWSTALLPTGAARVPLPTYPFQRRSHWLTPRPSAGSVVRELSPGRELSDGADPFAE
ETGASSPDSPARSKAESWRNRLTGRDAHDGRRLVLDLIRTEAAALLGHDSPDAVEERLAF
RDLGFDSLGSVELRHRLTLATGLGLPSSLLFDHPTPLRLAAALRGQLVGESADSAPVTAT
GATDEPLAIVGMACRYPGGSDSPEALWRLVAEGHDVIGPFPGDRGWDLDALYQPDPESAR
NGTSYVREGGFLHEAAEFDAALFGISPREALAMDPQQRLVLETAWEAFERAGVDPQSLRG
SRTGVFVGGTFQEYGPRLSEQGDGVAGHLLTGSAPSVASGRVSYAFGLEGPAVTVDTACS
SSLVALHLACQSLRSGESSLALAGGVTVMASPSMFVEFSQQRGLAPDGRCKPFAAGADGT
GWSEGVGLLLVERLSDAVRNGHEVLAVVKGSAVNQDGASNGLTAPNGPSQERVIRQALAN
SGLSAADVQAVEAHGTGTTLGDPIEAQAILATYGEGRPEDAPLWLGSLKSNIGHTQAAAG
VGGVIKMVMAMREGVLPRTLHVDEPTPHVDWSAGAVELLRENTPWTVGEDRPRRAGVSSF
GISGTNAHVVLEQAPAVEPVDAATDLEETAGVVVWPVSGHTADALRAQALRLHAWLEDHP
DADLPAVADALAGTRATLDHRAVVFGTGRGQLLDALSGIAAGTPTPHGVTGRYQAGKLAV
LFTGQGSQYPGMGHGLYTTHPAFRDALDEACAALDPHLPVPLLSVMFAGPGTPEADLLHH
TTHTQPALFALETALYRLVESYGVRPDALAGHSIGELTAAHAAGVFTLADAAVLVATRAR
LMGELPAGQGTMLTLHTTPDHITPLLEGTTLEIAARNSPTNTVVSGTVSDIETLTARAAE
AGIRTRALNVSHAFHSAHMDPVLDTFRTTLSTLNPQAPTLPVISNRTGQPLTPEQALSPD
YWTEQLRHSVNYTDITHHLDTTGTTTYLELGPDTTLTTLTTQTLPDATAIGTLHPKHPHH
HTLHTALATLHTHHTPLTWPTTTHPTHHHPTLPTYAFQHHHYWLNDTPAIRDLTSAGLAT
TDHPLLGATVEQAESGGTLLTGRFAQADHSWIGDHVILGATVLPGTALVDVVMHAAEHVG
CDTIEELTLEAPLVVTEKDAVQIQVAVGAPDETGGRSLVVYSRQAPAPVDEPWSRHARGR
LVAEPAAAPADFDWLPAGAQPLSLTDAYDMLALRGYEYGPQFRGLTAAWRSGDEVFAEVR
LPDGEPDSADAPFAIHPALFDAVLHATLLFGLAAESPDEAQDGLRLPFAWSGVRVHAVGG
PAVRARIRPTGEDTVSLTITDEAGGPVASVESLAFRRASAAQLSSARSNADVAAHYVVEW
NALAGRVWQPALSPHRWASVGAPTLGLLDDSALYGNMTELGAAVAEGATVPDFVSLTVSS
EAADDLADTANRTTQHVLRELQVFAADARLADAMLVVVTRGAVAAGEGELPGLSAAPVWG
LVRSAQAENPGRYLLVDLDPAAAEGLPPHHLTAAVQSAVAADERQIALRGETALVPRLGR
LDLSPAQPENPWDGAGTVLITGGTGALGAAVARHLVVRHAVPSLLLTGRRGAEAPGAAEL
RAELRALGVEVIVAACDTTDADALAALLGEVPDTYPLTGVVHAAGVLDDGLIHTMTPDQL
ERVLRPKVDTATHLHHLTRDLDLSVFVTFSSVFGVLGNAGQANYAAANSFLDALMQHRRA
AGLPGTSLAWGLWDTESGITRHLNAADVARMERNGVLALAPEDALPLLDSGCATGNALVV
PTRWNLNSLRAQAMAGQLPPVLRSLAPSTGRPGTASGRPGTRSPSASLTVRLTGLNKAEQ
ETLIRDLLRTEVATSLGHVAPEQVDLADSFKALGFDSLTSVDLRNRLSSSTGLRLPATLL
FDYPTPAALVEYVWSSATEAAAATIAGETAVAVTTPRSDDEPIAIVGMACRFPGGVTSPE
DLWRLVAEHTDAISEFPTNRNWNLEELYSPDPDHSGTSYTSEGGFLHDADAFDAAFFGIS
PREALAMDPQQRLLLETAWETLERSGIDPTSLKGSATGVFVGAMYHDYAHWAEQARESAE
GFALTGTFGSIMSGRIAYNLGLQGPALSIDTACSSSLVALHLACESLRKGESSLALAGGV
AVMSTPNTFVEFSRQRGLAPDGRCKPFAASADGTGWSEGVGLLLVERLPDAKRNGHEILA
VVRGSAVNQDGASNGLTAPNGPSQQRVIRQALANAGLSVADVDAVEAHGTGTTLGDPIEA
QALLDTYGKDRSSEQPLWLGSLKSNIGHAQAAAGVGGVIKMVMAMREGVLPQTLHVDEPT
PHVDWSAGAVELLRENTPWTVGEDRPRRAGVSSFGMSGTNAHVILEQAPAAEVTEPATES
DPEDGAGVLVWPVSGHTSDALGAQASRLHAHLAAHPEVTAEQVAHALTTTRAALTHRGAV
VATEYAELMEGLAALGEGAPSAHVVSGVTRPQGKTVFVFPGQGAQWPLMTADLLSTEPVY
AQSIDACAKALAPYVDWSLRDVLTDPAGELLERVDVVQPALFAVMVSLARLWEHHGTSAD
AVIGHSQGEIAAAHIAGALSLEDAAKIVALRSKALTSLTGRGTMASVTLPHEQVTEQIAG
YDSLSVAVINSPTHTVISGTTEDIHTYLDHCQTNNIQTRLLPVDYASHSPHVEALEEHLL
TVLADITPQAASIPFHSTTHPAQTPTDTTTLNNTYWYDNLRQPVHFHTTLTHLNNTGHTT
YIETSPHPTLTTPINQTNEETNDTPLTVTGTLRRHQHGPTQFRLAQATLHTHNTPTTWPT
PTTQPTTLPTYAFQHQHYWLNTPTGGGSDPTTLGLQHTNHPLLGAAIDAATEDRTTTFTG
TLSLRTHPWLADHSVTGTTLVPAALFLELAFRAGDEVGCDSVEELMLKAPLVLHGSETVR
LQVVVERADDAGRCSLTVFSSSKDADEWTRHAEGVLGTSADSVTGAGFAWPPAGGQDVER
VPAEEFYADLADRGYDYGDAFRGVRELWREGEVISAEVVLPESVRADAERFGMHPALLDA
VLHTALGGAGGGVLVPFVLSGVTLGRSGASVVRVRVTPTGEDAVRVDVADPAGQLVLTVA
SLVLRPAVGLEAARAAATADLPYTVEWTPGRLAATATATTSASASATAEEATPACAVLGD
DSWRLTAALEGMGVPVVSVSGNGAGDGPEFVLLPVGAPAGGTADGVPAAVRQATGEVLAE
LQRWLSEEQDQAQQRAAGARLVVVTHDAVTTGTGEESVDLSAAAVWGLVRSAVTENPDRF
LLADLDRHEDSLSTLIPALRAAVRHGEPQFAVRKGSTLVPRLARPTGPGSALVPPSHTGW
RLETTSPGTLEQLAFIPTSHADEPLAAGEIRVAIRAAGMNFRDVLISLGMYPGAAIMGSE
GAGVVLEVGPGVTDLGVGDQVMGLFLGGAFGPVSVTDRRMVVRMPSGWSYEEAAAIPVVF
LTAYFGLVDLAGVRPGEKLLVHAATGGVGMAAIQLARHWGLEVFGTASPAKRELLRSLGV
DAGHAASSRDLDFEERFRETTDGKGVDVVLNSLAREFVDASLGLLAPGGRFLEMGKTDIR
GADELAERWPGIRYDAYDLREVDPDRIAEMLADLRELFESGALTSLPVQPWDVREAPEAF
RFMSQARHTGKMVLTVPRTLDPDGTVLITGGVGVLGGLLARHLITTHGVRHLMLTSRRGP
AADGADELRAELTAMGAEVTVAACDAADREALAELLAGVPSDRPLTAVVHAAGIVDDALL
GALDTGRLDRVLRPKVDAALNLHELTRDADLAAFVLFSSAAGVFGTPGQANYAAANAFLD
ALAGRRRAQGLPATSLAWGYWAQTSGMTAHMGQADIARLSRQGIAPLAADAGLAMFDAAL
RTPYAQLVPVALDLPALRGQAESGELPALLSGLVRVAVRRAAAAGETARGDGQSLAERLM
PLPEARRLEELLAVVRANTAVVLGHGSADGLEADRTFKEFGFDSLTAVELRNRLNAATGL
RLAATLIFDYPTPQALAAHLRDELGLEGAGAEPSVLGELKRLEAALAVRPDAGTRAEVET
RLRTLLRRLDEDESSQRESGLDDATDDEMFALIEQELGLE
>A0A2X2M676|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces griseus|TrEMBL
MILTDLTAEDLEDVLAAKVRGADLLAERLADGAFERLVLFSSNAGVWGGARQGAYAAANA
YLDALAERLRAAGRSVTSVAWGLWDAEGMGGGEAGARLSRLGLRPMAPDRAVAALHEALG
MDETLVAVADVDWEQFLPAFTMARRRPLIEDLPDARQITAAGDREGADTNGASGLLARLD
GLDAADRLDLLSKLVCEEAARVLSHSSPDAIEPERAFRDMGFDSIASVELRKRLSAGTGL
HLPATVAFDHPTPRILAEHLGAELLGVAPDVPPSTRVFGDIDRLAGTLAEVAEDDAVRKR
VAQRLRELLDSCDTTARDADGMSAQLGSASDEEIFEFIDKRFKRS
>A0A377GBM6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Fluoribacter dumoffii|TrEMBL
MAAQLYNTLPLFKVIIDQCCALANPLLSYDLQETLLNTPENININHTRYAQPALFVYEYA
LAKWFLSLGIRPHALIGHSLGEYVAACVAEIMSLEDALRLVCIRAELIASLPENGAMLAI
AENVEKTESLLADFPGLVIAVKNSPQQTVVSGPREVIELLKIYCAENNLRSTAIATSHAF
HSPLMQPVVEDFYQEAQKVTYHQPKIALISNVTGLELKPEEMNAHYWCEHLQQTVNFYPG
VQTLMQQGINLYQEIGPKPVLTTQIQLLGDLTVLPSVTNTENPWPSLLAVLGELYLRGWP
IHWPALYMKPLFHIESLPKYPFAGKDYWLPAFNQQQDSLNAQWRKNLYHLQWEEVDWQTS
PVFPQSIALMARQESNIAQLIPLLRQHEITIVSIDREAKEETILSRLSGVSHVVYCCDAC
EEEVLSETHILTRLTQLLIKNEVHKPFIFLNPNSSVVASSLLALLKSIKQEYPRWPVQYR
EATFEPVDENCINILFGESEKDWIVRYENKQYYSPKILPLMPELILGNNTVYPEYTYLIT
GACGDIGQVLIEELLQQGVKNIVAVGRRNNPRIWSPVIQSYLKKDAQIHYYCCNIAEVQE
VERLIAEINKQLPPLASVIHAAGVAVDKPWLAVQKTDISLIMEGKVLGALNLHRATAACE
LKEFICISSIAGILGSQGQAVYATANAFLDALCDLRQQQGKPGLSWILGPVKNTGLFKKN
EESLTSYLATLGIAPISTEVVRAVVKEKMGINKIIVANFLSDDVSATQAKQVHTETLPTN
SLDKIPATGKGECSVEEILYMVQKILKAGKNDLLESHNWFEAGMDSILATQLVHQINKRY
EENIVSFKDIFQYASAKELAKQIQERLTGYKKQKSTSPAANTIPLSLQQLEVWNYLNSCQ
DKRAYQIPMEIKIEGALSREQFEYALKKTIQRHDIFSYGFHEILHQVNQHIHQDTPVCLE
FSEHYDSREVAEFLLAPIDLKQPPLVRNRLIRVNEQEHRWLIVFHHLICDGTTVTAFIQE
VMFHYDNQELEDTPQQYRDYVYWQWNNVLDLLDGSLKDYWLNHLKDIPLNVPLACSTQSP
MEARVISTSIPLDNLNETLAILEKNKLSLSNFILANLFDLLFKFFEREKQGIVVFFSGRE
DGNFTSVFGDTSNDVVITSHQNNDILKHAQTIQEQIVSRIDKQYLRMPMLPENGLQFPEI
SFDFQRGIDVKVTGSQLTVTAVKSGNVQNYLWGENPRILSFKASLEPSELKLALKYRADK
INDDVAQTLLMQWMELLARFIPQKNKKINEQQDNLTVIRASILQHNLWQLLKTHPDGMPY
YIPLVKELGKNFDLARLEKAMRVCISKNPALRTYFSSEGEKLELILTRKEFSLPLKQIKT
DNLYKTLGELLIEPIALESPPLLRWYLLLSPEEKPILLIRIHHLICDGLSAEIFLQQLEH
YLEPGEETGEEHDASYLNHIAEDYKNYELRLNQYAGYLSSLNFATKHETFLAKERYYGGI
VYQKITQEHTKKITDFCHANKISLYTFYLHLFCTGIARFSGNKEVYMSIVKSNRTHLQHY
RLLGYYADNIPLLVSINDNQLISQLQALQLKIVELISRFEFPVLQQDLKQINYRQPPFLF
NQYSLSDSLKFTPADYVFENIIQETKQVALWNYPNPEQCNLMVRSSSQGDIMGLIFNPGL
INEEQAQAVMNMMISELLSRIKVS
>A0A7Z6XI77|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. CBMAI 2042|TrEMBL
MSAKRWIARPQRVADPEVRVFCFPHAGAGAAAFAPWARRLPPGAELCAVRYPGRENRIDE
PPFEDLQLLLDALEQAVTPLADRPFIFVGHCSGSIVALELARRLGERRGRLPAALFVSSI
AGPARRSSESIHLLPRGAFFERVAQYGGIDESVLGDPEIMDIFEPTLRADFRVAEKGASG
HTARLGTPITAVGGAQDPFVTFEDLAAWRQETSAAFSLHHVEAGHFVLDQVMEQMMAALP
GHLHQAGLDRHSPRPAG
>A0A3E2YHC5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MW-13|TrEMBL
MTYRAFDLNEAGHDRIGEMLAELLALFEQGVLRPLPVRVWDVQHARRALRYMSQARHVGK
VVLRIPAPVDPDGTTLITGAGGALAGVFARHLVATGQSRHLLLASRRGPEAYRDLVAELT
RQGARVTTATADVADPDQVARLLAQVDPAHPLTAVVHTAGVIADATIGSLDESALDKVLT
PKVDAGWALHRATRDADLATFAVFSSVAATLGSPGQGNYAAANGFLDALARLRQQQGLPA
TSLAWGLWDTASAMTAHLGGNAHRRAIRATSAPLTEVEGTALFDLARQYGGVHLVLMNLP
PAAARPAAGAVPGMLRELVRPTGPVRRTAGQAATDTASERGRLATLSPAQRRSHLLDLVA
ASVAAVLGHRSADSVDAHRGFKELGFDSLTSVELRNRLATATGLRLPATVAFDYPTPVVL
AEFLDRELGGAAATAPVAVGTATALDEPIAIIGMACRFPGDVQTPEQLWELVTAGADVIA
PFPTDRGWDPDDLRIGDDGNAPRQGGFLHDAAEFDAGFFGISPREALAMDPQQRLLLETS
WEAFERAGIDPHTARGSSTGVYVGLIYHDYASQAADTTDELDGYVGNGSAGSVASGRISY
LFGLEGPAVTVDTACSSSLVALHLATQALRQDECRLALAGGVSVMSTPGMLTEFSRQRGL
SPDGRCKAFGAGADGTGFAEGIGMLLLERLSDAQRNGHRVLAVVRGSAVNQDGASSGLTA
PNGPAQQRVIRQALANARLTAADVDAVEAHGTGTPLGDPIEAQALLATYGQDRPADRPLL
LGSIKSNIGHAQAAAGVAGVIKMVLAMRHGMLPSTLHVDEPSPHIDWDAGAVELLTETRR
WPALDRPRRAAVSSFGISGTNAHTILEQAPAAAPAATPAATGEVPGGLVPCVLSARDAAA
LRGQARRLHGLVADRPDLTVAGIGRALATGRSVLEHRAVLLVPDRAGLLSALDAFADGQP
SPAVVEGTARGGRTAVVFSGQGAQRAGMGRELSAGHPVFAAALDEVCAHLDPHLPRPLRD
VLFASAGSADAELLDQTVFAQAGLFAVEVALFRLAESYGIVPDFVAGHSIGEVTAAYVAG
VLSLDDACALVGARGRLMQALPAGGGMLAVAADEAAVTESLAGLTDRVGIAAVNGPAAVV
VSGALDALDVLERTWSARGARTRRLRVSHAFHSPLVEPMLAEFRTVLDGLTFRPPLLPVV
SNLTGGIADAEEISTPDYWVRHVREAVRFADGVACLRQRNVGTFLELGPDAVLAGMVRTC
LPDDDPATSSVAVVAALRPGRPEPVSLLHALAELHVHGMPVTWSTLLPETGGHPVDLPTY
AFQRQRYWPNVGRLRAGDVAGAGLGAAGHGLLGAAVDLAGDGEVVLTGRLALATLPWLAE
HAVSGAVLLPGTALVELAVRAGDEVGASRVRELTIAAPLVIPSSGGVRIQVRVSAPGYAP
QRTVTIHSRPDDAPDAGWTRHADGVLEPASADEPGVGAWPPAGADEVDLTGWYAAFAERG
VAYGPVFQGLRRAWTGGGEVFAEVALPDDAAGDATRFGVHPALLDAALHPAALLFEESAA
PRVPFAFEGVQVHASGARVLRVRLTREGTGVRLVAGDEAGTPVVSVESLTLRELIGRATP
DAAARSLFEVDWRAAEVTPVVTVPAWAALGGPGPADAVGRVQRTVADLLTALDGGAEPPG
LLLLPATAGQEGAVPEAVDALASAVLAELRAWLAADALAESTLVVVTRGAVVARDGDAVT
DLAGAAVWGLLRSAQSEHPGRIVLADVDGDVDAGLVAVLARVAEDAAGGQVAVRAGRVFV
PRLVRAPAPSMHAPLVADAGTVLVTGGTGALGALVAEHLVRTHGLRALVLASRRGPASAG
ADELVERLAGLGATARVVACDVTDRKQVAGLVADVTSTGRLAGVVHLAGVLDDGLVEGLT
ADRLAGVLAPKVSAGWHLHEATAGLDLDLFVLFSSIAGVLGSPGQAAYATGNAFLDALAA
QRRQAGLPAVSLAWGMWDTAGMAASLGDADRARSGRAGLTAMSADIGLALFDAAVAVDRP
TLVPAVIDVPALRAAAVGGVVPPMLRALVGTTTARRQAGQGGDGLADRLARLTEDEGRAQ
VALLVRGLAAQVLGHDGVEAVPADRTFRDLGFDSLGAVELRNRVNTATGLRLGSTLVFDY
PTPQALAEHAYAELVGTRAAEVEPESQATVGGDEPIAIVGMACRYPGGVETPEQLWALLA
GGGDGIGEFPADRGWDLETLFDPDVDRPGTSYTRHGGFLYGAAEFDPAFFGISPREALAM
DPQQRLLLEASWETFESAGVDPQWLQGSRTGVFAGAIYHDYATRLMEMPGETEGYIGTGN
SGSVLSGRVAYTFGLEGPAVTVDTACSSSLVALHLAAQALRSGECDLALAGGVTVMATPG
TFIEFSRQRGLSQDGRCRSFAASADGTGWSEGVGVLLVQRLSDAQRDGRRILAIVRGTAV
NQDGASNGLTAPNGPSQQRVIRQALANARLSSQQVDVVEAHGTGTTLGDPIEAQAVLATY
GQDRPADQPLLLGSIKSNIGHTQAAAGVAGVIKMIMAMRHGVVPATLHVDEPSPHIDWSA
GAVALATEAMPWPAVNRPRRAAVSSFGISGTNAHVIIEQPPAEVVEGEAAGDAVPPVVPV
LLSARDEAALAAQADRWTRWLSADQHLGAVEVAWSSVTTRPALERRAVVVAAHRDDLLAG
LTALAAGNPSGAVVTGSAVERGPLAVLFSGQGAQRAGMGRELSGEFPVFAAALDEVCGLL
DPLLPRPLRSVLFAAEGSAEAGLLDQTVFTQAGLFAVEVALFRLVESFGVVPDFVGGHSV
GEIAAAHVAGVLSLADAAVLVAARGRLMQALPAGGGMLAVGGSEADVLSSLDGFAGRVGI
AAVNGPSSVVVSGEVLALDELEELWRGRGARTRRLAVSHAFHSPLMEPMLDEFRSVLGGL
SFAAPLVPLVSNLTGGLVEGDELCTPEYWVRHVREAVRFADGITALKTAGVDTFLEVGPQ
SVLTALVADALPAGGDVLAVAVQRRDRSESQALLAALGELHVQGVPVSWSKWFAGAGASR
VELPTYAFQHQRYWPESVARTRRTAGDGADAEFWTAVESGDLTALATQFGGDGSDLDTLA
PALPVLSTWHRARRQRALVDGWSYRVMWKRTDLAATPAGTWLLVSPQDDDPVTGARTEEA
AKALASAGADVLRLTVDPVRTDRDDLARRLAETLADRTVTGVLSLLGLRDQPHPDSPAVP
VGTAATLLLLQGLHDTGTKTRLWCLTQGAVGTGDGDAVRRVAQAGLWGLGLVAGLEHPHL
WGGLVDLPDDVEPAGWDRLVRVVAGAGDEDQIAVRPTGVFVRRLGRAAAAAPAAGERWQP
SGTVLVTGGTGALGAHVARWAVANGAAHVVLTSRRGERAAGAAELREELAAHGARVSIVA
CDVAERDQVAALLAELDQDPAPLTAVVHAAGAGDVGLLAETDLAGFAAVLAGKVAGAVHL
DELLGDRPLDAFVLFSSIAGVWGSGGQGAYAAGNAFLDALADQRRARGLAATSVAWGPWA
DGGMAGVEAQQALARRGLSAMVPDDAVHAMRYAVGQPRPTLTVADVDWAVFAPAYASARP
RPLLDDLAEAREALRAPTDEQPGGAADGLREHLRALPRTEQARHLIDLVRTHASAVLGHP
GTDRVKPQRAFKELGFDSLTAVELRNRLSAASGLPLPATLVFDYPNPTTLAEHLLDGLLP
EARRSDGADPSESTVRQALATIPLARLRDAGLLELLLNLTDAETGAAAESTDESLDLIDE
MDADTLVKLALDGSDS
>A0A086JYW5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii GAB2-2007-GAL-DOM2|TrEMBL
MSPIDFIRRPWLWLQGMSKYDCICCAAPNFAFEVVTRKMPDNVYEHLDLSRVCGFLSGAE
PIRASTIDRFCEKFGPKGVRRCAVCPAYGLAESTLIVTARKTFQTVPKLLIVDSFQLQHE
KTVVALKPEATVTMDSEEYQVLVGCGVPLEGVQVRIVDPETKKELPPGKVGEIVVYSSSV
ARGYFGRPDTTKETFCYSFTDLQGKQTPPLGMRTGDGGFMYEGELFVAARLKDLIIIRGR
NFYPQDIEEAVDKVAMVRPGSSAAFAIEVDGHEALAVAAEVRLEEGIKGLWLRVKRQFDR
SHYEQIVDVEPTLLFNYPTLSDVIDFFVRELEGKGSEDLAVSLEKTGARETTTAIIGAAC
NLPGGTTSLNAFWDLLMCGVDAIAEVPRSRWDVEEYFDPDPGADGKAYVREGGFIEDAEM
FDAAFFRISPSEAKSMDPQQRLLLEVAYESLYDSGYTREGLQRASVGVFVGCCSNDWYQV
CSQLELGISSYTTTSYAPSIIANRLSYTFGLLGPSMTIDTACSSSLVALHIAAQELQGGS
CMSAVVAGVNLMLSPHITVAFCKSRMLAPDARCKTFDASANGYVRGEGLGSIVMKRLSQA
EKDDDRILCILRGTAVNHGGRSASLTAPSGPSQQRVIRTALRQAELTPGDIYFVETHGTG
TSLGDPIEVGALKSVFGASRDAKTKPLILGAAKTNIGHLEGAAGIAGVLKAMLALRYKHI
PPNLHFKQMNPHIDVREFNVVVPTAPMAFPREDGGRLFAGVSSFGFGGANGHVILQEALQ
QPSGDKPPCKRHSKRSIICFMFTGEGYEVSCMGRHLYETDDVFKEIITKCNDILKRWLNV
SLLSILYPPADKKMEMDKMMCQARFGHTALFAFEYALAESMVSKGVKPDVVFGVGLGELV
AAAFSGVMSLEEALYVVTQRAKLIDNLPPFEGVMVACRVSEQEVEMALSEMEINSRQSIS
IAAVYGRKNLILSGEQSEIDNVLMKLNIAGRWKYLPVHNVLTMNLVSDIIPPFTHLMSTV
KLCRPKVRLVSSTTGEFVDKEALSGRFWSRQVSQTVQLQQAVGNIVASGCSLFVEIGPQV
VLTKLAQQSLNGNAKDVTWVPAYDTTSDDVRVFENAVMTCNEAIKIIGKERSLEEGQHGQ
EELIFHRKPFPWTEIPHPFLSGHKFTEKDDVVFENAFPRRAIPLIADHAVNGTAMMPGAG
MLEMVGAAALALDLRTTSGAVSLENISFERPMLIGAHRVTYEYNRRHSLGEGGGAGTSPR
TVRTPRLVNHAYTRLGFREKSAEKAISETAGPASTEGGRTPVAGHHHGSYTKAGVLEDIK
DYAHNVLRRAAQHAEEIDVHTPVPPSMAPPSIVARHPREGSYGSMSRTSGIMGSNDRGDG
LTVPLSVEMAIRCRVTKMKEVELSTVWDDEVTDHCFATIVIADKKQETYSSLQEVRCRCT
ERMDVNEYYDMLYDAGLQYGPRFRTIQELYRGEKEALARVHFVGNVKQDPFESGFLIHPA
VLDGALQAAGCLLEQSHSGNKVMVPVSVGSATLTKVEVFQPCWAHVRLEETKSKAATLNV
TIYDEVTREVVASLQNAVLRQVDPSASVVATIPKDLLWKVNWQLVVEGDKEVVGRTPKVL
FIGGNIELSEALENAMGSTCKTLSVDALPREKAELQKVLDAEQWQAIVYVEAVTAGVYDA
LDVMNAAVRLVQAHYLNLNSGKAVGALWFVTRDTVFRDNGADKPGVEIPAHAGLWGLAKA
ARLEMEVSAGSPISMGCLDVSGADVSSMAQQILHALKSKVLTMRETEVAVREDGLYVSRL
APQTEVDVRGAIEFHMPERGAISNLVLRPQAFASRLPPEDGQIELRVRAVGLNFRDVLNV
MGLYPGDPGPPGADCAGVVVAVGDNVEHIEVGDCVFGVAQGCLRTYVTTDSQLLRRMPES
MTFEQAAALPVVATTVEYALHDLAKVKAGDKVLIHAVTGGVGLVAVQLCKRVGATVYGTC
SGGKKDAFAKSMGVQYVSSSRDAKAFAEDMRTFLGEDGKVDVVLNCLIDDFIPESLKLLG
PYGRFMELGKRGVWSKEKVAAERPDVQYELIAVDEMMEKDPIWFGGMLVRVRGLVAEQKI
QPLPMHVFDLADTGENGGVAAFRFMQRAQHMGKVVLKIPSPVEEASKNGSIVITGGLGAL
GMVVAGWLAEEGARHICLLSRREEAPQPGEIPGWDWLRTINCDVQFFSCDVSKYDSIRSV
LRTIQTSVAPITGIIHTAGALADALLDSQTPELMKKVYNGKVQGAWNLNRALEELGLNEQ
LKLCVFFSSVTSLFGNFGQANYCSANACLDALAQWRRAKGLCCQSIQWGPWIEQGMAAEL
KQQVERNGMKGISNEVGLRVLHDAIRQQEKATPVIGCQAIKWKLFMHRYIEQPPFFTNIE
MDLQVTSHDSNTVLRNLPPSERRDYIKAQVAAAARQVLGSSSPPPFDTPLQDVGVDSLGA
VEFRNVLSKKLGVKLSATTLFDYPTLNAIIDHLCEVFGESSQKDNLSTKLGALSENDLVQ
EGMAIVSMSCRLPGNSTCPDLFWDMLMRCTDCVCDIPLTRWNAEEVYSEDPDLPGKCYTR
RGAFIENAEYFDNSFFGISPSEVKHMDPQQRLLLEVAYEAFAGAGLTKEKLLGANIGVFV
GACNHDWTYLIQEDKISAYTGTGSAGSVIANRVSYCLGLRGPSVPVDTACSSSLVAADFA
FEKLMLRDCTMALVTGVNLMLTPHLFIAFSKARMLSPDCKCKTFDASADGYVRGEGAGAV
LMLPYADAKAKQMTIQAVVKGTACNHVGRSASLTAPNGPSQAEVIRMALRRAGMKPNDLK
FMESHGTGTSLGDPIEVNAVRTVFAPGREKTKPLLIGAVKTNIGHLEGSSGIAGLIKACL
VLSRREIPPNLHFKTLNPHINIEDFPVQFVTDFVSLDSVESTRKKNTAGVSSFGFGGVNA
HVLLEEATRDQNATRKEENRPKICFMFTGQGSQYVGMGRHLYEKEPVFREAITRCVEIAK
EYLPLPLLSVIYPSPDERDKMQEAINETLYSQPAVFVISYALLELWKSRGVEPDMVMGHS
LGEYIAAVCSGVISIQDGLKLVLKRAQIMSRAPSRNGVMVACRATAEQVEEAIHTLFGDG
EKNVALASVNGLKSVIVSGNQQDVQAVLRQLGAASRAKMLRVSHAFHSPLVKDTVAPFKR
VLETVRLSKPRVMFVSTVTGKVARDELQNTNYWAEHITKVVRFCDAVQACIAQGAKIMVE
VGPRPTLSNMGKGCLPQTTADEVQWINSLEPETLSSAVFDSLSALAKAGSGAMPAVFDRK
FFPWTETCHPLLGGKNTRPDGSVVYSALLRDLVKALFLDHVVYGKALLPATCLIEMMASA
TTHMISNHDEEKLVALSQVVFEKPLLVPDETSLSVLVTVETRGQVRVASQVSNSEEEAED
HAVCQVNIVDALPAAPALTEIRARCKTEIEASQLYAQLHNVGLQYGPRFQTIVKVFKGED
EVLGLLQAQNVTNFETGFMMHPAVLDGALQLSAVLAFEKGSSRAMVPFGVDTVLLKSCPP
DKELWARVVMNRKGVSSASATVHLYDFDGEPIAVLMGVTLRPIEFNTAADIPRELLWEVE
WESAGSYSMPQDGSLATPSGTDDSGAEDVTRTPSPLVTGENENTPSREVPSALPGLSTET
PRASKPLSTDETSGAVLNKSVHSVLLVDYAGGHREVVASIRDTCDVEVEVLSKPGSPELY
AQQLRQFAEVVATKTETVPLSTILFLALDEATPAEQLAGGLLETVKVFAVEKFKKLPCIW
VLTSGAQGPTRSVVSPKHAGLWGLMRTVRLELEMQIGKMVRFGCVDLDKNLEVSVALHFI
LQKRTEEPFEAEMILRCPSEDSEKEPGTAEVVNRRERSASFVSVGPEPVVPSTTDASAKS
SVTSDRMALTPGALSCFDETANSTEKLIFNAFCPRLHRSPIPVRGAVELHMPERGAISNL
VLRPQAFASRTAPQSHECEIRVRAIGLNFRDVLNVMGLYPGDPGPPGADCAGTVVAVGSG
VRHLKVGDSVYGIAQGCLRTYVTTNGNLMRRMPESLTFEQSAALPVVAATVEYALHDLAK
VKEGDKVLIHAVTGGVGLAALQFCKRVGATVYGTCSGGKKAAYAKSLGVKYLTSSRDASA
FAEDMREFLGEEEKIDVVLNSLIDNFIPESVKLLAPGGRFMELGKRGIWTKAQMAAERPD
VYYETIAVDTMMQEDTVWFGGMLDRIRDHVDSGNIPPLPLHVFEMTDPLAGGVAAFRFMQ
RAQHIGKVVIRIASDLEVKIPSTTEPAATETAMLAEAGTQGNASIGTSTQQIADRTYLIT
GGMGGLGLVVAQWLVEEGARHIVLLSRRGEPSDTVKQSSIWEYLTEKERTCVSVLPLKCD
VSVKDDIVSAVKEIEARGFPPI
>K9Q7S9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc sp. PCC 7107|TrEMBL
MSAYSIDTALAELEAQINSCEKTLIRFIEEKKMTTDKPMSINKINRQLQQNPIAIVGMAS
LFAKARNLREYWQNIINKIDCITDVPSSHWSVEDYYDPNPRTPEDKTYCKRGGFIPEVDF
NPMEFGIPPSILEVTDVSQLLSLVIAKEAMEDAGYGESREFSRETIGVVLGVAMAKQLGM
PLAARLEYPIWEKVLKSSGLSDEDTKKIVDKIKSAYVKWDENAFPGMLANVVAGRIANRL
NFGGINCVVDAACASSFGALKLAISELIEHRADMMLTGGVDTDNTIMAYISFSKTPAVSP
SESVKPFDAKSDGMMLGEGIGMIVLKRLEDAERDNDKIYAVIKGIGTSSDGRYKSIYAPR
KEGQVTALRRAYEDAGFSPATVGLMEAHGTGTMAGDPTEFGSLRDFFGVHDQKKQHIALG
SVKSQIGHTKAAAGAASLIKTALALHHKILPPTINITEPNPKLDINNSAFYLNTETRPWI
RAEGDAPRRAGVSSFGFGGTNYHVVLEEYEAGQNQPYRIHGTPQEILLFAENPAQLLSKC
EADLWKLQSEGAERHFAQLLQDSQSVEIPQTAARVGFVAENLQETCKLLQISIDWLKLKG
AAASWEHPQGIYYRASGMELGGKVVALFSGQGSQYLEMGRELVMNFPEMQRLHGYMDSLL
LKDNLQPLSEIVFPRPTFEEAEKNAQVAALQRTEYAQPAIGVFSAGLYSILQKAGFKSDF
VAGHSFGELTALWAAGVLSEADYLFLVKSRGQAMAAPEDPDHDAGTMLAVKEDINKIEPI
LKQFPQVSIANFNSPTQVVLAGPTAEIAKVRQALQEQGYTAVQLPVSAAFHTSLIAFAQK
SFAIATKSVKFNTAQIPVFSNVTGKPYPQDSTGMQRILETHLASSVLFKQEIENIYAAGG
ACFVEFGPKRILTNLVKDILGDRPHITIALNPSTQKNSDRSLREAAVQMRVIGMQLKNLD
PYQVQPALPPAEKKKTLSVRLNGINYVSEKTRNGFKEALESGHKVSLPAAPAPVVSATPE
FSETNRQEIRVLENSGVNFQEIIKPEPAPEVTSTTSITEPQPEMNPAILSNQLAQETDMP
TPENLVNNQRMLESLEYLLTQFQKNQSDNLQTHGQYLNHQMEYTKAFFQLMQQQNALFAN
AKSSQEVAQLKLVVMEGVERSMMQFHSQQGETLRIHEQYLLEQVEYAKNFFNLIQQQYSQ
LIAGGVAVEPSNTPVSDAPVPPTTKIVAPTPVVEPVAKNGNGNGYAAKPVEMPAAPAPQP
VAVAPTPVIETPIALVPQPVAFTPAPVIETPVAPAPQPVVVAPAPVVQIPTPQPVAVISA
PIVATPAVDISDLDKNLLAIISDKTGYPVEMLELEMDMEADLGIDSIKRVEILGGLQEMY
PNLPKPNLEELAEKRSIGDIITYLQSNASGNPSVGVAVLPAPVAPEMPVTTLPVVPIVPV
APAPEPVVIAETPVAETVEDTTEYADIAQTLLNITSDKTGYPVEMLELEMDMEADLGIDS
IKRVEILGTMQETYPNLPKPNVEDLGDLRTIGQIVEYLQRLVAGEKKKPDSNWGFQPVQV
IENVARRPAQLKILSLPDSLEFSLPEGHICLITDDGSLTTSQVAQSLTERGWKVVVLSFP
QAIIAQQAPLTAGVERITLADMSEELLQHKLSAIATNIGTIGSFIHIHPQGVEQDKAIVK
HIFFVAKHLKKPLTETANYTRSSFLTVVRLDGAFGLEHNTNYGAIAGGLFGLTKTLKWEW
PKVFARSIDLSPAIDPQKSAEHIIAELCDSNLYINEVAYGSQGRVTLKASVVK
>S8F5N9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii (strain ATCC 50611 / Me49)|TrEMBL
MTSDLTQALLSCLEAVTEPDSEDTPNQRTDAEYRFCAVRQDDITFAEFLNRVSVQFEVPI
GPLAAKDYESFSSFVFHICELKKEKQVNVKTSSHHIIHRTNRYSTENEKASISIVGIACR
LPGNAKNPGDFWTVLVEGIDAIVPIPSKRWNHKEFSEGHSERGTIYVKEGGFIDGIEKFD
NGFFKISSSEARRMDPQQRMLLELSHEAFESAGLQAITDDNHKFGVFVGCSSSEWPFDAA
ANGYGRGEGAVVFLLERQMYSPESRCKQKSLATIRGHGTNHNGRSVSVTAPSDVAQKKLL
EGVLRTASVEPQQVAYLEAHGTGTKLGDTIEFRAIKSVFSTSRSVDNPLLIGSGKSNVGH
LEGCAGAVGLLKALLVLYFREVPPTLHFKKISPLIDDEGFDYQIPTKRLTLAGDRPILAG
VSSFGLGGCNAHVIIESVPKDREMDALSLSRRHIWDHMEFPVFESADDGNSFGGLAMRHN
VDLCNSTCNHLRRRSTSSLIGKCTLTPVSARLRRFTAFSSGDGTPGLRVQQYGTTEGSSK
ANEPHAITEKQISRWTRDSRKGLYVEVESMKDELERSFSLEDDNGSVTGSVQTEQTEPDQ
MANEVVNTVDEEAVQTLVLQTVRQILKEAVSIHRDVSLKTLGIDSLAAVEFRDSLQESLG
ISLPASLIFDFPTIDDVCRFLAQKLQSGDGGERRNTPTNLAQPRPSTSSETCVAVRGMSC
RFPGAEDGTTESFWEMLHSDSDCIQEIPTSRFDAASIFDTDYGARDKIYVKAAGILRGAD
MFDNTFFKISEVEVRHLDPRQRILLEVAYDALVDSQVLGDQGLAAIDNEIVGVVIGCSGN
DWNTFLQQHALSASSFSGPGTSPALLSNRVSYNLSLRGPSLTVDTACSSSLVAIDIARQL
LNASQCNLALVGGVQLLLTADTFIHYCRARMLSPDCRCKTFDASANGYVRSEGCGVVLLE
NTHDRQVSKNTTYAWLLGSANNHVGKSASLTAPNGPAQQAVILASLRSAHLQLTSQIHLI
ETHGTGTSLGDPIEIGALQAVYGQGTSADTPLVLGALKSRIGHTEGAAGIAGFIKLICSL
RQRIAPPNLHLKTFNPHIDISTADSSRPFLFPTKAYPLDTLMAGEKTEALLGAVSSFGFG
GSNAHAIVEVPARQGPTGRDAAYAGLRGADAATEAHQPMVWLFTGQGSQYVNMAKSLYET
EESFRQTVKECSAYLATEKLLPTEGPSSLEDIIYPGQDADAEEAEHLLMQTQYSQVAIFV
VELALTRVLKERGLRPAAVLGHSLGEYAAAVTAGVFSWRDALRVVAVRARIMSEQDPQDG
VMAACRLSAAEVQAALDSDLKNLKSVAVAADNGPRSVVVSGRRSEVEEVLSFFSISGRAR
FLRVSHAFHSPLMAGAVEPVSRLFERVEFSEPAIPFVSSARGRLTITNELGDSIYWGQQV
AVPIKFREAIAAVESVFGSASVHFVEVGPCAVLVHLGPNCCMPSAGARHRWSFAVGDTLA
KARERDVSRLVVCEAQAGSKEPGHTWHRKRFPWKASLHPLLGLREATKNEHVQEHIYQKA
VPRALVKVFSEETSLGISTLPAAAVLDAMIAAAKLCSRMGSPGDDTSKAAIQLKNFRSYR
EMVLPEPQDCDSTNVVLNVCFRLVTERETLVIASFGSYARFPTDVDGSKGKWLPLTEATV
MPVSNAKNQCPTLYALQRRFLKDETMSKQEATDTWRTAEDWGVPERFTTIRAIHRRDDEA
LVHLSRARTLVEEGFIVCPVIIRELFCVAGTIAKRQVPFDRDLDYAVTGVETVNSFATSQ
DACDSFWGHIHVLPLTSGHAQKRLANVTLYTEKGSVTVQLQAVQLHPTARVSVQREIDMQ
QSLLQACCHQPEGVVDPVSQSHTTRDSCHQSQSLRKTYTHDELIRLVTEACRRVIGTDSE
PDVRTPLQELGIDSLGAVAFRDALEDTFHLKFPATILFDHPHLDALSHFISWRLEEKVEE
TEPTGISVPLSFDTMDGDVAVIGMSCRLPGSSNTASDFWQALLTTDNFVAEIPPTRFDIE
EFFDPDQGAKGKMYVREGGFVDGATLFDNRYFGISAAEAHEMDPRQRLSMEVAAEAFCDA
GVEQNDAASEETLVVVGKTNTDAVRVGYSQLSPFSCSGANNSILSNRISYFFGLTGPSMT
IDAACASSLIAIVAGFNELTRGGCKTALIVGVNLLLSPECYIEICKATMLSPDCRCKTFD
AHANGYVRSEGCCGVILKTLPRNTKTLKENAIYAWIRGAATNHVGRSASLTAPNGPAQTT
LMLDTLRSARLQRVSDISVLETHGTGTSLGDPIEIGALQAVYGQGTSADTPLVLGALKSR
IGHTEGAAGIAGFIKLICSLRQRIAPPNLHLKTFNPHIDISTADSSRPFLFPTKAYPLDT
LMTGEKTEALLGAVSSFGFGGSNAHAIVEVPARQGPTGRDAAYAGLRGADAATEAHQPMV
WLFTGQGSQYVNMAKSLYETEESFRQTVKECSAYLATEKLLPTEGPSSLEDIVYPGQDTD
AEEAEHLLMQTQYSQVAIFVVELALTRVLKERGLRPAAVLGHSLGEYAAAVTAGVFSWRD
ALRVVAVRARIMSVTVRMRDERSSRQAAGPEMHQESAFASMAPDELRALIQATVSGAAKQ
VLGTAEEPPADAPLQALGIDSLGAVEFRNAVQDAFDIRLSATLLFDYPSVQAVSDHLWSM
VRAKTAIDTSSRGDDQLASAAVLQDAGVSIAVVGMACRLPGSVNDLEAFEEMLLTFQDCI
QEIPPSRFSIEEVYDPDPDAKGKIYVREGGFIDGAELFDNRFFGISDAEAREMDPRQRIS
LEVSYEALVDAGYSREDLLGSPIGVFVGAMNHDKLHDSMMHANSLTATGAAVSILANRLS
FAYGLTSSSLTVDTACSSSLVAIDIANKDLLLRVCDGGLVVGTNVISTPQHFLDTSRSRM
LSRDCRCKTFDASANGYVRAEGCCALILQRTSTPQTHTRIYAALAGTASNHVGRSASLTA
PNGPAQQAVIRAALRSANVNSPLSVAVVETHGTGTSLGDPIEIGALQAVYGQGTSADTPL
VLGALKSRIGHTEGAAGIAGFIKLICSLRQRIAPPNLHLKTFNPHIDISTADSSRPFLFP
TKAYPLDTLMTGEKTEALLGAVSSFGFGGSNAHAIVEVPARQGPTGRDAAYAGLRGADAA
TEAHQPMVWLFTGQGSQYVNMAKSLYETEESFRQTVKECSAYLATEKLLPTEGPSSLEDI
AVSDHLWSMVRAKTAIDTSSRGDDQLASAAVLQDAGVSIAVVGMACRLPGSVNDLEAFEE
MLLTFQDCIQEIPPSRFSIEEVYDPDPDAKGKIYVREGGFIDGAELFDNRFFGISDAEAR
EMDPRQRISLEVSYEALVDAGYSREDLLGSPIGVFVGAMNHDKLYDDLRQLTSYSGTSTA
LAILANRLSYSFGLVGPSVTIDTACSSSLVAAEYATLCVACGRSRQAVVHGINVIPKVEG
ANVNSPLSVAVVETHGTGTSLGDPIEIGALQAVYGQGTSADTPLVLGALKSRIGHTEGAA
GIAGFIKLICSLRQRIAPPNLHLKTFNPHIDISTADSSRPFLFPTKAYPLDTLMTGEKTE
ALLGAVSSFGFGGSNAHAIVEVPARQGPTGRDAAYAGLRGADAATEAHQPMVWLFTGQGS
QYVNMAKSLYETEESFRQTVKECSAYLATEKLLPTEGPSSLEDIVYPGQDTDAEEAEHLL
MQTQYSQVAIFVVELALTRVLKERGLRPAAVLGHSLGEYAAAVTAGVFSWRDALRVVAVR
ARIMSEQDPQDGVMAACRLSAAEVQAALDSDLKNLKSVAVAADNGPRSVVVSGRRSEVEE
VLSFFSISGRARFLRVSHAFHSPLMAGAVEPVSRLFERVEFSEPAIPFISTVLGRLAVGS
ELSDALYWSEQITKSVRFREAVVAAFGGAVAGLSAVEHMAEVLLSLKRMGLDTSRVCGLG
AISSMETLQNLVQGGTWAGMLVVSGLWATVSAVESLTETAHILRHYACLSTEIEVPVLAV
VTRGAQRSVVSPETFGQRERPTLESVPQQNQVFGHLEDEVPVHAGLLAFCRTLRLEMGRC
CRRFKPFLYFDTDRLHPRQSKESLDYRLGAVLKWLSRNDVPASFSEQIRPDSDTLREWDI
VIRKQSYFVPRVAPVLLKQPSTTAAGRIQKAKSYIVTGGLGGIGIVVASWLLRQGAGRIF
LWSRRGVPTDDVKETNQWCELNAAMETGRIQTVSCDVSEIEQVRHSIVLAVTDSILGGIF
HCAGTEGKGKLQDVSQQDIADVNALQEALKIKLPASLLVEYACLKDIIQFIMENCFSDAA
RSTSDLVPLVTREPAANDQGFAVVGMGCRIPKNATTTEEFWDMLLHEIDAVCEIPMDRFN
IDAFYDPDPEQDKCYTREAALLDHPDFFDNTFFNLSDQEVLAIDPQQRVLLEVAYEALFE
AGFTKEALLGKDFGVFCAAYNNDFQFTNLTQGKATMCVFDKGEGRGRIPSLGEAAGYPEP
GGFMCFIPNRISYSFGLTGPSIGIDAACASSLVAFDAAVTKLKRGACSGALVGGVNIILS
PTFFLGGCKAHQFSRAGRCKTFDCNADGLVRGEGCGAAFLLPLDAARETGAFVHAVVRGS
ATCHYGRSSQITSPNTRALTRVLRLSLQDASTAPSLVRYYEAHGTATVLGDVIEMSAVKD
VFQTGRNAAAPLHMGTVHNNIGHLDAAAGIVAFLKTVLCLKHRFVPANIHFKSLHPDIHG
IDTQLIKYTRESHSIMTDDVATGVRKTIFGANLAYGMGGSVAAIITESGDEEADRRSLKA
APRHVWNHRRFPLNTQKFVYLMGAMGQISMDDMPTPQSDVIHVMKRLSATALNVAFMRKL
SPSTCAAGSIRSVFLTGATGFIGSQVLFHLLQVKRQDPKLGTEDKKLTIYCLVRARDRAH
GIYRIRDSLVGRGIEWKHEFDQQVIPVIGNLEEGENMGLGPKQMQYLEQTVDAVYHAADY
VNFAAPYDALRKSNVLSLIPILKLCTTYVAKPLHLVSNFAHHLQYFAGFSEDLNIAVDET
VSPPLSPASIDRLEQQMPAGIIGYPWTKWAVEEIIGRMKDVLHERCEEEGQRVSMEESEK
KDILSKFQVTVYRLPNSCVYYNNGYTNFANASLSLVLASAQERMIPPGVLPVGAPFLTTP
VDLITGILVKLSMTERKRHHVYHLVSLRVARRKHVVQAIKWLFPDSVECTADELFRRIDE
NKENSPAHPLRAAMRFWRRYWYSSDTDRDSPFPVAVNNVEDDLPGVMATFPSLADTWLRM
ASYCVKNYHMVRHPVTLAISFERLKKAIAGITKQRIDELALPSQTQELLNETCSTEDTTD
IAAVKALVEHANLRKYDDCAVSDVPDPRARA
>B7JWG0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Rippkaea orientalis (strain PCC 8801)|TrEMBL
MTTSKQQEAIAIIGMGCRFPGAKNPSEFWQVIQTGVDTIKEVPRNRWDIDQYYDSNPDSP
GKMNTCWGGFLEKVDEFEPSFFNISPREAERIDPQQRLLLEVVWEALENGGVIPETLSGS
NTGVFIGLTNQDYHRLLYQEIDQLDAYYGTGTSASIAANRISYFLNLQGPSFTVDTACSS
SLVAIHLACQSLHQKESNLAIAGGVNLILTPEQTITFSKSRMMSPDGRCKTFDAKANGYV
RSEGCGVVILKRLEDALQQGDDIQAIIRGSAVNQDGLSQGLTAPNSLAQQRVIRQALHNA
QIESDRISYVETHGTGTALGDPIEVKSLKAVLMGDRTADQPCWLGSVKTNIGHLEAAAGV
AGLIKLVLCLQNQEIPPILHFNQLNPYISFKNTSFVIPTTSQTWIVNDQTRVAGISGFSF
GGTNCHLIVEESPRVKGTGINNKNKTEIDRPVHILTLSAKTEDSLNELVKNYYNHLQSEG
NLSLSDICFSANIGRSQFEHRLAIISQSREQLKEQLQVLQEEKKTSGYFAGKVLEETYPK
IAFLFTGQGSQYIGMGQELYQKSPLFRQIIDQCDQILRNELDESLINIIYPEQGTQTREN
TNLLNQTIYTQPALFTIEYALAKLWQSWGIEPSVVMGHSVGEYVAACLAGVFSLEDGLKL
VAARGRLMQSLPEDGGMVAILATVEQVNQVINSYQNEVAIAAINGSDSLVISGKKEAIQS
IIKTLESQGIKTKLLSVSHAFHSPLMEPILEDFRNIAGTISYSSPTIQIISNVTGKSITE
EIMTPDYWVNHLRSPVQFLDSMQELLNKNYEVFLEIGSKPILLGMGRNIVEKMDNYSTNQ
TWLPSLRPGRSDWEQLLESLGQLFIKGSVIDWHKFDQDYQRNRVIIPTYPWVRSRYWIDK
NNLNQRQKNKSITLPLSQRKNQSINTHKVVRLSNLRQQLEQNYQSSAFVQQLEKTFEAER
LPKIINYLQQEIRTILGLNKTQIPPHTMGFFQMGMDSLMAVEFRNKLEATFSITLPTTLA
FNYPNIEALSNYILEKINRRFKLEEKSHSNGQSAINKLEQLAQEIEAYPEEEIERLLIEK
ITTILEK
>A0A0N1JU30|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Amantichitinum ursilacus|TrEMBL
MNTIRALVLNEYGDQNATQIGHIAAPTAGAGQVLVRVRAAGINALDWKVREGYVRDAFPL
QLPTVLGIELAGVVEAVGPDVTHLRQGDRVMGALGDLGAYAELVAVNAANLIKTPDALSD
VDAAALPVATVSAWQSLHHAGPLHAGQRILIHGAAGGLGGFAVQYAHRAGAVVYATTRSS
QVATVQRLGADHVVAYDQAQFENTMRDIDLVLDYVGGEVLDRSWRVLAQDGAIVSTASPA
IVASTPPGRRGLWFINTPDSALLQQLADDVAQQRVQSRIGAVVPFADLPAAIERNRTQPQ
PGKSLVDFSL
>C6E970|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Geobacter sp. (strain M21)|TrEMBL
MKTDDLKPAASSNGTQLAIIGIGCLFPKADDRDAYWANIADGIDAITEVPETHWPVDAYY
DANQKSPDRTYGRRGGFLSPVDFNPMEFNIPPNVLEAIDTSQLLGLVAAGQALKDAGYGP
ERSFDKSRASVIIGVTGTLELVIPLGARLGHPIWRSALKDAGVDEATANDVVERISDSYV
PWQENSFPGLLGNVVAGRISKQYDLGGTNCVVDAACASSFSALHLASMELASGKSDIVVT
GGIDTFNDIFMYMCFSKTPALSPSGNAKPFDVSADGTILGEGLGLVVIKRLADAERDGDR
IYAVVRGVGSSSDGKGDAIYAPSAAGQKNALLNAYKNADVTPQSIGLIEAHGTGTKVGDA
VEVSALRDVYGESELPWCCLGSVKSQIGHTKAAAGSAGLIKAALALHHKVIPPTIKVQTP
QKEVVGEKSPFYLAKEKRPWFPRADVPRRAAVSAFGFGGSNFHVVLEEYRADKKAADWDG
NTQILAFSGADAARLAAGLDRVPADAAWSAVRELAFQTRASFDAKGALRLALVIERGRTN
VASLVKNAKAMLEKNSKSAWQTPDGAFFGCGAAGKLGMLFPGQGSQYTGMLNDLACRFPQ
LLNAVTAANEGFTSAGGRRLSDLIYPPSAFDEETRSKQEEALRATQAAQPAIGAVSLGAL
RLMQSFGLEPEAVAGHSYGELTALCAAGRLDESALHALSRLRGELMGAGKGDKGSMLAVS
APLSKIAEVVAAEKLDLVIANKNAPSQAVLSGACAQIKRAVELFKGRGLTCKELPVAAAF
HSTLVADAATPFLAALAKIEMHKAKIQVFANTTAAVYPADAAAAKAQLASQLAMPVEFVA
EIEAMYAAGITSFVEVGPGNRLTGLVQAILADRPHSAVALDASSGKRAGVADLGRTLAQL
AVLGFGVKLASWDEGYRPAPAGKKPLLSIPLCGANYQKPKPKKPPVQPKPAVVAAAAAPQ
AAPVAMNAPAAQPPAYQAAVAAPREAIFQAAPSAAAAPQAALSESLRLAREGMAVLQRMQ
EDTAQLHRRFLEGQETATRTFQTLLQQQQQLILGASISPAAVAPATVPVQAQAQAYVAPA
PVVAPAAQVTAPAAKAPVAPAAPAAPAVAASPAPAAPAPASVGADSARITQVLLAVIAEK
TGYPVEMLELDMGMDSDLGIDSIKRVEILSTLQERLPGTPAIGPEHLGTLRTLGDIAGHL
CASTAASAPAAVATAAPAAATSGLAAEQITSTLLLVVAEKTGYPVEMLEFDMGMDSDLGI
DSIKRVEILSTLQERLPGSPAIGPEHLGTLRTLGDIAGFLSASAVSAPAAAAAPAVATGS
AIAAGEITSTLLLVVAEKTGYPVEMLELDMGMDSDLGIDSIKRVEILSTLQERLPGTPAI
GPEHLGTLRTLGDIAGFLSASAVSAPSAASAPAVVTGSAVAASEVTSTLLSVVAEKTGYP
VEMLELEMGMDSDLGIDSIKRVEILSTLQERLPGTPAIGPEHLGTLRTLGDIATYLAAGS
ATAAPAGAGGASPLAASAAAPAQPVAPPAAASSDPARIMTTLLEVVADKTGYPVEMLEPG
MGMDSDLGIDSIKRVEILSTLQERLPDTPAIGPEHLGTLRTLGDIADFLVGASSAAAPAA
EGAAAAATAAAVEANQAVAAEPVPAPVQAIERSSVTPVELSADEEGEAIVLANDGEIWVT
DDGSAFASELCGILLEHGCSVRKVNAAEAQQTAPAGKLSGLVICAPMSGTDDIFLENAFQ
LVKNAAGALNESARAEGAVCVTVSRLDGAFGFGSGKSIKDPLSGGLAGLAKTAALEWPEV
SCKAIDLGEFPHAAAAAGAVAIEMLRRGPVEVGLSSKGRFALQTVVLPCAPAPAEPAIKA
GDVVVITGGGRGVTAISALALAKEYKPFLVLLGRSSEPEEEAAWLAGVSGEAEIKRVIMQ
NAVGKLHPREIEERYRAVVAGRELRDTLQKISAVGAEAIYRSVDIRDRSAMELLLGEVRR
AHGPIRGVVHGAGVLADRLIVDKTPEQFGQVYSTKVEGLRALLHATRNDELRFIALFSSS
TGRFGRVGQVDYAVANEVLNKVAQGEARRRGDCRSVSINWGPWDGGMVTPALKKVFAAEG
IGVIDLAEGGEFLAKEISAAGAPVEIVAIAQLPEQKGAAAPAPSAAKQENLSEAFALTLT
VPEFPFLRSHVLDGKAVVPMAVIVEWLAHGALHGNPGFRFHGFNDLRICKGVVFEDNTSF
PLSVLAGRAVKKESFWLVPVELSSPGVNGRTILHARAEIVLATKHVEGIRSITEIPATAY
APHDGVIYNNERLFHGPDLHGIEHVDGCSAKGIAASVKGAPAPGKWIRRPLRSAWLTDPL
VMDSAFQMMILWSFERFGAGSLPCFAGRYRQFQESFPKEGAQVVIRVTSENPRGASADME
FLDRNTGKLVARLEGYECVIDPSLKQAFQRNKLRTVSVALGAA
>A0A086J639|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii p89|TrEMBL
SVRFREAVVAAFGGAVAGLSAVEVGPKRTLANIGAAYVNGATHPGCAWLCVIEGPATSES
GSQFESFLKQVASLSSRKLHWNHRTFPLARLQEQKTEDAGQNLRSMAKPSPHSQPSIWSE
KWAYHSSVPENDAAFKVPKKAWIIVGVPSQHMAEVLLSLKRMGLDTSRVCGLGAISSMET
LQNLVQGGTWAGMLVVSGLWATVSAVESLTETAHILRHYACLSTEIEVPVLAVVTRGAQR
SVVSPETFGQRERPTLESVPQQNQVFGHLEDEVPVHAGLLAFCRTLRLEMGRCCRRFKPF
LYFDTDRLHPRQSKESLDYHLGAVLKWLSRNDVPASFSEQIRPDSDTLREWDIVIRKQSY
FVPRVAPVLLKQPSTTAAGRIQKAKSYIVTGGLGGIGIVVASWLLRQGAGRIFLWSRRGV
PTDDVKETNQWCELNAAMETGRIQTVSCDVSEIEQVRHSIVLAVTDSILGGIFHCAGTEG
KGKLQDVSQQDIADVNALQEALKIKLPASLLVEYACLKDIIQFIMENCFSDAARSTSDLV
PLVTREPAANDQGFAVVGMGCRIPKNATTTEEFWDMLLHEIDAVCEIPMDRFNIDAFYDP
DPEQDKCYTREAALLDHPDFFDNTFFNLSDQEVLAIDPQQRVLLEVAYEALFEAGFTKEA
LLGKDFGVFCAAYNNDFQFTNLTQGKATMCVFDKGEGRGRIPSLGEAAGYPEPGGFMCFI
PNRISYSFGLTGPSIGIDAACASSLVAFDAAVTKLKRGACSGALVGGVNIILSPTFFLGG
CKAHQFSRAGRCKTFDCNADGLVRGEGCGAAFLLPLDAARETGAFVHAVVRGSATCHYGR
SSQITSPNTRALTRVLRLSLQDASTAPSLVRYYEAHGTATVLGDVIEMSAVKDVFQTGRN
AAAPLHMGTVHNNIGHLDAAAGIVAFLKTVLCLKHRFVPANIHFKSLHPDIHGIDTQLIK
YTRESHSIMTDDVATGVRKTIFGANLAYGMGGSVAAIITESGDEEADRRSLKAAPRHVWN
HRRFPLNTQKFVYLMGAMGQISMDDMPTPQSDVIHVMKRLSATALNVAFMRKLSPSTCAA
GSIRSVFLTGATGFIGSQVLFHLLQVKRQDPKLGTEDKKLTIYCLVRARDRAHGIYRIRD
SLVGRGIEWKHEFDQQVIPVIGNLEEGENMGLGPKQMQYLEQTVDAVYHAADYVNFAAPY
DALRKSNVLSLIPILKLCTTYVAKPLHLVSNFAHHLQYFAGFSEDLNIAVDETVSPPLSP
ASIDRLEQQMPAGIIGYPWTKWAVEEIIGRMKDVLHERCEEEGQRVSMEESEKNDILSKF
QVTVYRLPNSCVYYNNGYTNFANASLSLVLASAQERMIPPGVLPVGAPFLTTPVDLITGI
LVKLSMTERKRHHVYHLVSLRVARRKHVVQAIKWLFPDSVECTADELFRRIDENKENSPA
HPLRAAMRFWRRYWYSSDTDRDSPFPVAVNNVEDDLPGVMATFPSLADTWLRMASYCVKN
YHMVRHPFTLAISFERLKKAIAGITKQRIDELALPSQTQELLNETCSTEDTTDIAAVKAL
VEHANLRKYDDCAVSDVPDPRARA
>A0A2K8QYV0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MATSSERVVEALRASLRENDRLKLQNQRLVAASKEPIAIVGMSCRFPGGVRTPEQLWQLV
VDGVDAISEFPTDRGWENETLYHPDPDNPGTSYTREGGFLYDADEFDPQFFGMSPREALA
TDPQQRLLLEASWEAFERTGIDPVSLRSRPVGVFVGTSGLDYATHLYEVGGELEGYLTGS
AASVVSGRISYTFGLEGPAVTVDTACSSSLVALHLAVQALRQGECDLALAGGVSVMSSPG
SFIEFSRQRGLAVDGRCKPFAEGADGTGWSEGVGLLLVERLSDARKNGHPVLAIVRGSAV
NQDGASNGLTAPNGPSQQRVIRQALASAGLSATEVDAVEAHGTGTTLGDPIEAQALLATY
GQGRPEEQPLWLGAIKSNIGHTQAAAGVAGIIKMVMAMRHGILPKVLHVDEPSRQVDWSA
GEVRLLTEATAWPETGQPRRAGISSFGLSGTNAHTIIEQAPAADPDEQQEATAPRADAAK
QSAVLPWLVSGKSAEGLSAQASQLHAHMSAHPELSPADMAFSLATTRSAFEHRAAVVAED
RDGLLRGLEALANGENAAQVVQGVARIEDTLAFLFSGQGAQRLGMGRELYEAFPVFARAL
DEVCAHLDVLLDRPLRDVMFAVEGGADAELLHQTAFTQPALFAIEVALFRLLEHWGVTPD
VVIGHSVGEIAAAHVAGVFSLEDACTLIAARGRLMQALPEGGAMVAVQASEEEIAPALAG
REAEVSVAAVNGPTAVVIAGDEAAVLEIAEQWSEQGRKTRRLRVSHAFHSPRMDAMLDDF
RRVVEALSFAPPSIDLVSNVTGKVADAEVCSPEYWVRHVRAAVRFADGVRTLDAQGVTTF
LEVGPDGVLSAMAQDCLAERAGEGSAPVALPVLRKDRSEAVALTTALARLHVHGSVVDWR
PAFDGLEARRVDLPTYPFQRQRYWIEKSADGTGVDAGIRDEVDAWFWQAVEREDLASLAK
TLDFDDEATLGAVLPALSAYRRSSRNQSTIDGWRYRVSWKPVADVAGGALSGTWLVVVPA
SRAEDELVAGVVSGLERHGAGVVSLVVDERDLDAGVLGERLGEVVAEVPELGGVLSLLAL
DEGSCPGYPALSAGFASTLTLVQALVGVGAECLLWCVSRGAVSVGRSDRLAGVVQSQVWG
LGRVVGLEHSAVWGGLVDLPEVLDERAVGRLVGVLSGGGGEDQVAVRGSGVFVRRLVRSA
AAVGEGVSWRARGTVLVTGGTGALGARVARWVVGQGAEHVVLTSRRGPEAPGAEALRDEL
VALGARVTVAACDVADREQLAAVLETVPEEFPLRAVFHAAGVEQAAELVGMGLADAASVV
SGKATGAGHLDALLGDRELDAFVVFSSIAGVWGSGGQAAYGAANAYLDALVEDRRARGLA
GTAVAWGPWAEGGMATSEGMEGELVRRGLAVIPPTLALTALHGAVAGDDGVVTVADVDWK
RFAPLFTLERPSPLLGDLPEVGRALDAATSPGRTGDASTGLRQRLAGLTEAEIGRTLLDL
VRGQAAAVLGFTGAEVVEPGRAFKELGFDSLTAVEFRNRLNAETGLVLPATLVFDYPSAT
VLADHLRAEVLGTQGAVATPSAVVAAVDDDPIAIVGMSCRFPGGVGSPEDLWRLVAGGGD
AISDFPSNRGWDVDGMYDPDPERLGTFYAREGGFLHNAGEFDAGFFGISPREALAMDPQQ
RLLLETSWEAFERAGIAPTSVRGRQIGVFVGAATSGYGVGHDGAAGELEGQILTGNATSV
VSGRISYTLGLEGPALTVDTACSSSLVALHQAAQALRQGECEMALAGGVTVMATPGAFVE
FSRQRGLAPDGRCKPFADAADGTGWSEGVGMLLVERLSDAERNGHQVLAIVRGSAVNQDG
ASNGLTAPNGPSQQRVIRQALANAGVSAAEVDVVEAHGTGTTLGDPIEAQALLATYGQER
PEGLPLWLGALKSNIGHTQAAAGVGGIIKMVMAMRHGVLPRTLHVDEPSREVDWSAGEVR
LLAEAMEWPETGHPRRAGISAFGVSGTNAHTIIEQAPAADGEAEPAPAAPAEDHGIVPWA
LSARSAEALRAQAERLRSYLVERAELGALDVGHSLVATRAVHEHRAVIAGANRAELLRGV
EAVASGEVAPGVVQGVANASGVMAFLFSGQGAQRLGMGRELYEAFPVFADAWDEVCAHLD
VLLDRPLREVVFAAEGSADAELLDQTAFTQPALFTIEVALFRLLEHWGVRPDVLIGHSIG
EIAAAHVAGVFSLEDACTLVAARGRLMQDLPEGGAMVAVQASEEEIAPSIAGREAEVSIA
AINGPNAVVIAGDEAAALEIAEQWSGQGRKTRRLRVSHAFHSPRMDAMLGDFRKVVEGLS
FQTPSIALVSNVTGEAASGDDVCSAEYWVRHVREAVRFADGVRVLDKLGVTRFVEVGPDG
VLSAMARDCLMADAGSASVVAPVLRKDRPEVQALTAALAELHVHGVEVGWERVFAGRGAR
TVELPTYAFQHQSFWLEDRAEASGGSAADSVDARFWDAVEREDLEALAKALDVDGGGSLG
ELLPALSSYRRQQRDRATVDGWRYRVSWKPVPEPAAGPLSGTWLLAVPAGLADSELTVTI
TQGLEKHGAHVVPVSVDGGMDRDGLAEALRGALGDESDASVLSLLALDEEPCAGEPVVAA
GLALTLRLVQAAAGLDAGLRLWCASRGAVSVGRSDRLASTAQAQVWGLGRVAALEHPQIW
GGLVDLPETLDERAVSRLAGVLSAEGGEDETAIRGSGVFGRRLVRTASTGGEAWRPSGSV
LITGGTGALGAHVARWAVREGAEHVVLTSRRGLAAEGASELRAELEGLGAAVSVVACDAA
DRDALVEVVAAIPERFPLRGVVHAAGVLDDGVLDGLTVDQLAGVLGAKVEGARLLHELTA
DLELDAFVLFSSFAGVVGGAGQGAYAAANAYLDALAVVRRGAGLAGTAVAWGPWAESGMA
ASGRAGERVRGGAVSAMAPALAVDALSWAVGQEEASLVIADVDWERLAPSLAAARGGTLV
SDIPEAHKHLATDDGGGATEAATFAGKLAGLSAAERNEAVLELVRGHAASVLGHTTADSI
EPGRAFRDLGFDSLTAVELRNRLDLATGLRLPATLVFDYPTAAELADYLDAEAFGTAQPA
LDTTRQNAVAVDHDPIAIVAMSCHFPGDVHTPEDLWRLVAEGADAISEFPTDRGWDLDGL
YDPDPKRLGTSYAREGGFLYGAPQFDARFFGISPREALAMDPQQRLLLETSWEAFERAGI
APESLRGARAGVFVGTNGQDYAGLWVDSQGDLEGHLGTGSAASVVSGRISYTFGLEGPAV
TVDTACSSSLVALHMAMQALRQGECDLALAGGVSVMSTPGAFVEFSRQRGLAPDGRCKPF
ADAADGTGWSEGVGMLLVERLSDARKNGHPVLAIVRGSAINQDGASNGLTAPNGPSQQRV
IRQALASAHLSTADVDVVEAHGTGTTLGDPIEAQALLATYGQGRSEDQPLWLGAIKSNIG
HTQAAAGVAGVIKMVMAMREGVLPKILHLDEPSREVDWSAGEVRPLTEATAWPETGRPRR
AGISSFGLSGTNAHTIIEQAPAAEGPAASDTVAPASAPVPASVSASETVESTVVVPWLVS
AKSQEALRAQAGRLAAHVAARGDLGVLDVGYSLAAKSVFEHRAVLVGEDREALLRGLEAV
AGSGIASGVVQGQAVPGGKTAFLFSGQGAQRLGMGRELYEAFPVFARALDEVCAHLDVLL
DRPLRDVMFAAEGSADAELLDQTAFTQPALFAIEVALFRLLEHWGVTPDVVIGHSVGEIA
AAHVAGVFSLQDACTLIAARGRLMQALPEGGAMVAIQASEEEVAASLAGREHEMSIAAVN
GPTAVVIAGHAQAVQKVADTWTAKGTKTRRLRVSHAFHSCLMDSMLDAFGHVVREVSFEP
PTMALVSNVTGELASEGETCSPDYWVRHVREAVRFADGVRSLKALGVTRFLEVGPDGVLT
AMAQDCLAESAEDTSAAVLVPVLRKERPEAGALITALAELHTHGATVGWESIFAGRGAGK
VELPTYAFQRERFWPEVSAAGGGRDSGATSADSVDARFWEAVEREDLEALAEALDVDGNA
PLSTVLPALSAYHRSNREQSTIDGWRYRVSWKPVADVAGGALSGTWLVVVPASRAEDELV
AGVVSGLERHGAGVVSLVVDERDLDARLLSERLREVLATAPELGGLLSLLALDEGSCPGH
PALSAGFASTLTLVQALVGVDAECLLWCVSRGAVLVGRSDRLAGVVQSQVWGLGRVVGLE
HSAVWGGLVDLPEVLDERAVGRLVGVLSGGGGEDQVAVRGSGVFVRRLVRSAAAVAEGVS
WRARGTVLVTGGTGALGARVARWVVGQGAEHVVLTSRRGPEAPGAAELREELEALGARVT
VAACDVADREQLAAVLETVPEEFPLRAVFHAAGVEQAAELAQMGLTDAASVVSGKATGAG
HLDALLGDRELDAFVVFSSIAGVWGSGGQAAYGAANAYLDALVEDRRARGLAGTAVAWGP
WAESGMAAGDGGDQLARRGLPAMAPGLAMAALHGAVAGDDGVMTVADVDWERFAPAFTIG
RPSPLLGELPEVVSALEQARAAEESHAEGGSRLRERLLALAPGERERAVLDLVRGHAAAV
LGFSGMEGVESDRAFKELGFDSLTAVEFRNRLNADTGLRLPTTLVFDYPNAKTLAEHVRA
GVLPDEGTSATPLIADLEKLEASLSTAEPDSAERMAIAARLQVLLARLNGDEGGAKDAES
ITQRLDGASDDDLFDFIENELS
>A0A2K8RJE1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MSAQGLHETDTAIAVVGVSCRLPSAADPGRFWRLLTGAVSAVSPVPPGRWSDEDVAAGSD
GAGWGAFVDEVDRFDAEFFGISPREARAMDPQQRLALELGWEVLEDAGILPDAVRGGGTG
VFIGVTADDYGVLDRRRGPAAIGHHTLTGLNRSVIANRVSYFLGLRGPSLVVDTGQSSAL
VAVHLACESLRRGESAMALAGGVQLNLAPDSAVAASLFGALSPDGRCFVFDERAGGYVRG
EGAGMVLLKPLARALADGDEIYCVIEGSAVGNDGPGEGLTTPDPEGQETVLRAACRRAGV
DPAAVQYVELHGTGTRVGDPVEAAALGAVYGAGRGADNPLLVGSAKTNVGHLEGAAGIVG
LLKVVLSLRNGELPASLNHELPNPAIRFDEWRLEVATSTRPWPYRDGRALAGVSSFGMGG
TNCHVIVSAAEPAPTGVLAGAGTDGRAGMADSALMAGGAVPWPLSGRTRDALRTQAVRLA
SHLADNHRLDPVDVGFSLATTRTAFRHRAVVLAPDRPGAPDALTALADGESAPGVVRGVA
DVEGKTVFVFPGQGSQWAGMGVRLMAQSPVFAERLAECAAALAPHVDWSLPEVLRQAPGA
PSLERVDVVQPASWAVMVSLAAVWQAHGVVPDAVVGHSQGEIAAACVSGALSLEDAARVV
ALRGQTIARRLAGSGGMLSVPLPLAEVEARLRRWDGRVSVAALNGPGSVVVSGELDALDE
LFEELTGADVRARRVAIDYASHSAQVEQVREEMSAALEGLSPRRAEVPFFSTVTGEWLDT
TGMDAGYWYRNLRQTVGFEPAVRALLGQDHRVFVEVSTHPVLTAGVQDVIDEADVRAVAV
GTLRRDMGGADRFLTCLAEVYVRGVAVDWSRAFAGTGARRVALPTYGFQRERYWLPELAG
GATARDTATAAPAAVLGHTARPEPEPESEPGPERVASDASWTRAGLGRLVRAEAAVVLGF
TSAEQVNPVLSFRELGFDSAMTVELVARLKAATGLRIPNTVLFDHSTPDRCADHLAADLT
GPVTAGTPTASSAVPVDAPADDPVVIVGMACRYPGGVNSPEELWDLVSGEVDAVSDMPTG
RGWAPEITETGRPGGFLYDADRFDAALFGISPREAEAMDPQQRLALEASWEAVERAEIAP
SSLHGSRTGVFMGAMAQDYGPRLQDSAGSAEGYLLTGTSPSVLSGRIAYALGLHGPTLTV
DTACSSSLVALHLAAQALRGGECSLALAGGVTVMSEPGIFVEFARQGGLSPDGRCKAYAE
GADGTGWSEGVGVLVLERLSDALRGGHRVLAVLRGSAVNSDGASNGLTAPSGIAQRQVIG
QALAGAGLVPSDVDAVEGHGTGTRLGDPIEAQALLATYGQGRDADRPLLLGSLKSNIGHA
QAAAGVGGVIKMILAMHHGVLPRTLHVDAPSSQVDWSAGAVELLTGSVPWPPAGRPRRAG
VSSFGISGTNAHVIVEQPPRDRPDDSAGRAPAAPRARTVPEVAPWPVSARTEAALDAQLD
RLAAFVADTGATAPDIGYSLATTRSELEHRAVLLAAADTTGHGDRRPVTVARGTAVGDPG
PVALLFAGQGAQRLGMGRELHARFPVFAAAWNEVCALLDGELERPLREAVFGDHAETLDR
TEYAQPALFALEVALYRLVESWGAAPDLLIGHSVGEIAAAHVAGVLSLSDACRLVAARGR
LMQRLPEGGAMVALRATEDEVAPLLADSGDRWGLAAVNGPQSVVVSGDAEAVEAIADRFA
ADGRKTTRLRVGHAFHSPLMAPMLDDFRAVVEGLSFGEPRIPIVSTVTGERIDAEHIRGR
DYWVEHVSRTVRFADAVGAAAAAGARTFLELGPDATLSVLAEDALTDVAHVAVVPLLDRE
RGEESTAVTAAARLYVRGVPVRWAELFAGTDVRRVALPTYAFQRDRYWTAPAAPPAADVA
SAGLERMAHPLLGAVVELPENGGLLCTGHLSVTAQPWLADHVVAGHTTFPGAGFVELAVR
AGDEVGCGLVEELTVAAPLVLSGQGERGVRVQVSLGASGDGGRRTLGIHSRPVGTPEAPW
TRHATGVLAPGTPTADPAPDPDAGRVWPPADAVPVDLDGFHERWRAAGLAHGPVSRGVRA
VWTAGDEVLAEVVLPEHAVADADAYRLHPALLETALHIVALTGPDGPDGGWSAPTRSEAS
SWSGVLLHAVGASVLRVRLRRTREDTVTLTAADAAGDPVLSVRTLTLRPQAVPTTGATAE
PPLLRLGWLPARVPDSAGHDRVAIGDAVLVPVTVPTGVPVPEAVRTVTASVLDTLRQHLD
DAAGTGDADEAGGDGGGRRSLLVFMTRGAVATTPGTAPDVVAASVWGLVRSAQRETPGRF
VLLDLEATDGEDEADGRGGGHPVPTDPATLRAVLDCGEPELALRAGELLMPRLFPADAPA
DVPDPAAPGPVWGGEGTVLVTGGLGSLGAMFARHLVTAHGVRHLVLAGRRGADTEGADEL
VAELTGQGARVTVAACDVSDRAAVAALLATFPAEHPLTGVVHTAGVLDDGLVQALTPDRL
DTVFRPKLDAAWHLHELTRDRGLTAFVVFSSVFGVLGNAGQAGYTAANAFLDALAQRRTA
EGLAGLSIGWGPWPQDIGGMTASLSAVEMRRITRGGMAEFSVDQGLSWFDIAAAVGEPFV
VAAHVDRAALRARDTVPAVLRGLVPARSARRTAAAAIATGGGLDPLAGLTADQARVTLLR
WVREQVMAVLGHTSSAAVEAGRTFKDMGFDSLTAGQLRNGLRTRTGLSLPSTLIYDHPTP
ETLAAHLWTELGGAAGERRESAGPAPITAGGPAAGATAAEPIAIIGMSCRFPGGVRSPEE
LWELLAEGTDAICPLPADRGWGPGVYHPDPERTGTTYSAAGGFLDGVAEFDAAFFGISPR
EAVSMDPQQRMLLELAWEAFERAGVDPTSLRGSTTGTFVAATAQQYGAGASADSDGYQLT
GTLPSVLSGRLSYLFDFSGPAVTVDTACSASLVALHMACQSLRSGESTLALAGGATVLSG
PDTLVSLSRHRVMAPDGRCKAFAESADGMGIAEGAGLLVLERLSDAVRHGHRVLAVVRGS
AVNSDGASNGLTAPSGPAQRRVIRQALANSGLSASDIDAVEAHGTGTALGDPIEAHALMA
TYGQDRGGNPPLLLGSVKSNIGHTQVAAGVAGVIKMVMALRHGRLPKTLHAAEPSSRIDW
DSGAVRLLTEAAPWPELGRPRRAAVSAFGMSGTNAHAVLEQAPPAADQPPLADAAPDGPV
AWPLAAKSAGALRAQAAKLLAHLDGHPGQRPEDIGYSLAMTRAAFEHRAVLVGGDRAALR
GSLAALAEGTSTAGAVRGTAAERGTVVFVFPGQDGAWPGMAAELLDVSSVFAARVADCEA
ALAPYLDWLPSAVLRGAPGAPPIERRPDVLQPVLWTVMVSLAALWRSWGVEPAAVVGHSQ
GEVAAACVSGGLSLDDGARVVALRSRLIHERLSGRGAMMSVMAPPERVRELLDGTSDAVS
IAAVNGPKTVTLSGDPAALAEVERALSAAGIMRWRLPGVDFAAHSAHIDEIEAELMELLA
PVRPRPSTVPFHSTVTGGRLDTEELDARYWCRNLRETVSFAETMTGLVREGHGFMIEVGP
HPVLAVGTGEIIENANSPAVTLGTLRRDDGGWDRVLRSLGEAYAHGVPVDWSTVLPGGHT
VDLPTYAFQHESYWIAPPASGPGTTAVADEPLWDAVDQGDAAAVATLIGLEAESKGALDS
VLPALSAWHRRQDEHALTSARRYRTVWTPLRVPVDPALTGTWLVLTTDGDGDAEVPTALT
AYGARARRVVLDESCTDPEVVAARLREAGLDRAAGVLSLLATAEEAAGGEPALPTGVALT
ASLLQALMAAGAEAPLWTVTRGAVSTGPADPVRNPRQAMVLGLGRTAALEAPSLRGGLID
LPERLDPEAVRRLAALLSAGPGEEQAAVRSSGVLVRRLVRAPARADSPGAWSPGGTTLVT
GGTGTLGSRAARWLAQQGAEHLVLTSRHGPAAPGAAELVAELTAHGTTAEVVPCDLTDRD
AVAAVLDRLSADGRPVRAVVHTVGTRDLEPLETASLTSLARAVHAKVAGAAHLDELLDDT
GLDAFVLFTSVAGVWGIGHHAAQAAADAYLEALASRRRGRGARATAISFTPWEEARDRMS
EQEREYLARTGVSFLDSDLALTGLAQALYEDETALTVADIDWERHLPFVTPAAPIPFFSE
LPEARSLDEPVTTGDDGEFTARLRGLPAEERRHVLVELVRSEAAAALGHASGQAVDEHSA
FRDHGMDSLAAIDLRNRLATAMGTALPSTVVLTHPTPAQLADHLVDHLASPSAKEDGGTG
GTDGVATTDLVVRLHRHAVRTGRMNEAGTLLLDLAALRPKNTEPLPPTVDRLTADTSGTR
LICVAPIVPLTGPHTYFTLAGALPGDWAITCLTPPGFGTEATLPATRETLVEGLVHAVET
STDGDPADPVVLLGTSSGGILAHETARRLAERGTPVRAVVLVDTYILESPAAQGLQPQLW
HALYEREHLADGYTATDLSAYAWMERLLHTWTPAPTPFPTLLLRASDPLPAPDGTDPVPH
GWQTDLPHMTTTVTVVGNHFTLVNQHAPTTAGHITEWLAERGTGGNTGGDADVLEGAAGT
GERTA
>A0A5B7V2M6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MTDDDRTLDYLKRLTAELGQTRERLRAVRAAGREPIAVVSMACRFPGGVTSPEELWRLVG
SGTDGIAALPTDRGWDTEGLYDPDPDRPGTTYAREGGFLADVTSFDAGLFGISPREALLM
DPQQRLLLEVSWETFERAGLTPDALRGSRTGVFTGMMGQDYTARLPGTLTEYEGQLETGR
AASVASGRVAYTFGLEGPAVTLDTACSSSLVALHLAVQALRNNECDLALAGGVTVMSSPA
TLLEFSRQRVLAPDGRCKAFASGADGTGLAEGVGVLLVERLSDARRHGHPVLAVVTGSAV
NQDGASNGLTAPNGPSQQRVIRAALANAGLTGADVDAVEAHGTGTSLGDPIEAQALLATY
GQQRDGDRPLWLGSLKSNIGHSQAAAGVAGVIKTVMALRAGTLPRTLHADEPSPHVDWSR
GAVRLLTEARPWPREDRPRRAGVSSFGISGTNAHVIVEEAAEEPVPGATGITGITDVTDL
ADAGSGGGAGSGGGAGSTAPPPVPWVLSARTPEALRAQAARLRDHLRDRPGLRPLDVAYA
LATTRAPLAHRAVVVGRRADELLRGTAALAAGEPGPDLVESVARDLGKAVFVFPGQGSQW
PGMAVELMDASAVFRERMLACATALGPYVDWSLSEVVSGTADAEVTDRVDVVQPVLWAVL
VSLAELWRSHGVEPAAVVGHSQGEIAAACVAGALSLDDGARVVALRSRLIAGKLAGAGGM
VSVAAPAADARARLERWGDRVALAAVNGPSSVVVSGDPAALDELLADCERDGVRTRRVAV
DYASHSPQVELLRDDLLAQLAPLRPRPGKLPLYSTVTGDVLAGEELTADYWFRNLRRTVR
LSDAVERLAATGHGAFVECSPHPVLALGLTETLGELGGDALVTGTLQRDDGGPDRFLRSL
GALHAGGRSPDWERLFAGTGARRVDLPTYAFDRQRYWLDAAPVAGDATAVGLSPLDHPWW
GAATELPDSGGTLLTGRVSRDSAPWLGDHAVGEAVLLPGTAFLELAVRAAEQAGCDRVAE
LTLQAPLVLPPRGGSQLRALIGPADAHGARALTLHARPEDAPDAPWTTHAAGSLAPAEQG
GGGALAAWPPPGAAPVAVERAYADLAELSLRYGPAFQGLRAAWRLGDELYAEVALADDAE
PEGFAVHPALFDAALHAVALDDAGAPADAGPRLPFSWSGVEVHAVAATRLRVRITRLGPD
AVALLAADATGAPVVSVESLAVRPVPLDDLRPAAGKPTDALFAVGWAPAPGTAAAPPRSW
AVLDGLDALAPALEATGAAVRREPDLAAVAAGPGDVPDVVLAPLKPCSGDLPTAARETVG
ATLTLLQEWLGDDRFAAARLVLVSRGAVATDDDGTADPALAAAWGLVRSAQAEHPDRFVL
FDWDGGEPSADALPAACCGDEPHLALRAGEVHVPRLRRVPVDTAPAAAEASGRFDGDGTV
LVTGASGVLGRAVAHHLVTAHGVRHLLLVSRRGAAAPEAAELTARLTESGARVRWAACDL
ADRAALAAVLADVPRDRPLRGIVHAGGVLDDGVVSALTGQRLDTVFRPKVDAVVHLHELT
EGADLTAFVVCSSAAGTFATAGQGGYAAANAFLDAFARARRARGLPALSLAWGLWERASA
LTARMSDTDRDRLRRSGVTGLTAEDGLALLDAGLTGGLPVVVPTRLDLSAVRARAAADGV
PPLLRGLVRPPARRAAADTADDSALTRDLAALAPGDRAAKVLDAVRAQVAAVLGYAGPTA
VEPGLAFKELGFDSLTAVELRNRLARVTGLRLPATLVFDRPTPQALAEHLLDRLTGQGTP
ARTPAPQPAAVPADEPIAVVGMACRFPGGVGSPEDLWDLVDRGGDAISAFPTDRGWDPGS
AAHAAQGGFLRDAAGFDPEFFGISPREAVAMDPQQRLLLEVSWEALERAGLDPTTLRGSR
TGVFAGLMYHDYTTRHATVPDDAGGYLGTGGSGSVATGRIAYTFGFEGPAVTVDTACSSS
LVALHLAVQAVRGGDCDRALAGGVTVMCTPHAFTEFSRQGALAADARCKPFAAAADGTVW
GEGAGVLLVERLSDAVRAGRRVLAVVRGSAVNQDGASNGLTAPNGPSQERVIRQALAAAR
LTAADVDAVEAHGTGTTLGDPIEAQALLATYGQQRPVERPLWLGSVKSNLGHPQAAAGVA
GVIKTVMALRRGVLPRTLHVDAPSPHVDWSAGAVELLAEARPWPETGRPRRAAVSSFGIS
GTNAHVVLEQAPATADGEAPAAPRGDGGPAEAAAGPVPLTVSARSEPALRAQAARLRARV
AADPRLDPVDVAHSLLTARAALAHRAVVLGGDRDALLAGLAAVAQGRETPGAVEGLAGDP
GRTVFVFPGQGAQWAGMAAGLWETAPVFRERLTECADALAPYVDWSLVDVVRGAPTGVDP
DRVDVVQPALWAVMVSLAELWRSYGVEPAAVVGHSQGEIAAACVAGGLSLADGARVVALR
SRALTAIAGRGGMVSLALSAADAEKLVAAQDGRLSLAAVNGPASVVVSGDTAALDALLDR
CAETGAWARRIPVDYASHSPHVEAVRERIGHDLAELRPRTGDVAFFSTVTGGFQDTAGLD
GAYWYRNLREPVRFEPAVRELFDRGYGAFVEASPHPMLTVGVAETLAEQPERTGVAVGSL
RRDQGGLERFSASVAEAYTRGVAVDWTAAWAGRAPHVVDLPTYAFQRRRFWLDTPAGSGD
VTAAGLGSAAHPLLGARVELAGSAETVLTARWSLDTHPWLADHAVGDTVVVPGTAFLELA
ALAGAEAGCPRIAELLQEAPLVLGARGAVRIQVRVAAPDDDGGRALGVHARREDAPPEDP
WTCHARGLLTEEGPEAPPALDGVWPPPGAEPVDLTEFYDRMDDIGLSYGPAFRGLHTAWR
LGDEVLAEAALPAEDQAGADRYRAHPALLDAGLHSCLLRTPDTGGAAMPFAWNDVDFHGP
CGPAVRVRVSPGAAQDVSVLVTDADGTPAVSVGSLAARPVPPEQLRAAGGAGNSLYRLAL
VPAPATAPAPPGAWAVLGDEATELPAPAGEFADLAAYRAALAAGAPAPEAVLVPLPVAED
LDDDAARARALTYRTLDLLQSWLTEGGAGDAGPAEDPADPSAAPDPSAAPDPLTAPGPAD
SAPPARLVLVTRGAPAPPGSDDEGLVDPAVAAVQGLVRSAQAEHPGRFVLVESDGHPEST
AALATALATDEPHLVLRAGRILVPRVERAPAPHGGEPPWDADGTVLVTGASGTLGRAVAR
HLVTAHGVRHLLLVSRRGGEAEGAVPLAAELADHGAEVTWAACDAADRAALAEVLGAVPA
AHPLTAVVHAAGVLDDGVIPALTPDRLDRVFRPKVDAALHLDELTRTARPVAFVAFSSAA
ATLGGAGQGNYAAANAFLDALVLRRRRQGLPAWSLGWGLWADTSAMTAGLDRAGRARLAR
SGLRELATDEGLALLDAALAGTEPLPLPMRLDTAALRARGDALPPVLRGLVRGGDRRGGA
SRAAGAAALRRRLAALTPAERDLHLSDLVRAETATVLGHPSPEAVGRDRAFKDLGFDSLT
AVELRNRLTAATGLRLPATLVFDHPTPAALATRLAAELAPPDGADEARRDTEAAVRAALA
AIPLPRLRDAGLLDALLELASRPAGRDEPPREPDEPGSIDHLDSEALLAMALDNGAHANT
EDHDAPW
>A0A5B7V4G1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MATDEKLLQYLKRVTTELHQLRKQGSSHAGEPVAIVGMACRLPGGVTGPEELWRLVREGR
DAVSGFPDDRGWELDGLFDPDPDNPGTSYTDQGGFLRGAGLFDAGLFGISPREALAMDPQ
QRLLLETSWEALEQAGIDPVSLKGSDVGVFSGVSSQGYGAGAGAIAPELESFTGTGVAGS
VASGRVSYVFGFEGPAVTVDTACSSSLVAMHLAAQALRQGECSMALAGGAMVMSTPGTFV
AFSRQRGMASDGRCKAYADGADGMGLAEGAGVVVLERLSVARERGHQVLAVIRGSAVNQD
GASNGLTAPNGPSQERVIRKALAGAGLVPADVDVVEGHGTGTALGDPIEAQALLATYGQG
RDPRRPLWLGSLKSNIGHTQAAAGVASVIKVVQALRHGVMPPTLHVQEPTAEVDWSAGAV
ELLTEAREWPRDDRPRRAGVSSFGISGTNAHLILEEAPPEAGEPLPERAEPGGAVPLVVS
ASGAGALAGQAARLTTYLQSWEPGDSGGVDLADVAGALLSGRALLGERAVVAARSAEEAL
TGLRALARGESTTGVVSGRVTGSGDVGKVVWVFPGQGSQRAGAGRELYERYPVFAEALDE
ACEELDARLAGWVDHPVRDVVLGTVAGSADLLDQTVFTQAGLFAVESALARLVESWGVRP
DAVIGHSIGEVTAAYVAGALTLPDAARLVAARGRLMQALPPGGAMVAVAAREEQVAGLLR
EGVEVAAVNGPAALVLSGDEDAVLAAAGPLRERGYKTKRLAVSHAFHSPRMEPMLADFTA
ELADVAWQRPAIPVVSNVTGRLAGPDELSDPHYWAAHVRRPVRFAEGVAAAAEFGGTLFV
ELGPGAALTGLVEETATATTAEVTCVAALREGRPEEVTLLASMAELFVRGVAVDWARLLP
AGAASRRVDLPTYAFDHQQYWLKPGASATDAASLGQTAADHPLLGAVVRLPHSDGLVFTS
RLSLRTHPWLADHAVGGVVLLPGTGLVELAVRAGDEAGCGSLEELVVEAPLAVPARGAVR
VQVAVGAPGETGTRTVEVYSQREDDGDADTWTRHAAGLLSATARPRGRDGFDFTAWPPPG
ARPVDVHPGDFYDDLAERGYGYGPAFRGLRTVWRRGDELFAEVALPEEQREEADRFGIHP
ALLDAALHAGMLAATADPAGEEPARPVLPFAWNGLVLHAVGASALRVRLTPGGPGAVALA
AADETGGPVVTMDSLVSRPVSEGQLESAADTAAATALFGVEWTELPPPQGEPQQWLPVAT
ADEVAALAARADVPPVAVLEAVGGDGEDAVLALTARVLEVVQAWLTEASLEESRLAVVTR
GAVPAGTGVVSDPAGAAVWGLVRAAQAENPDRIVLLDTDPAAGGPLDAVLGAVLEAGEPQ
VAVRGMRYSAPRLARVTGEVSDVPNKFGSGKSVLLTGGTGSLGGLVARHLVARHGVRHLL
LASRRGAEAEGAAELVAELVGQGATVSVVACDVSDREQVRALLASVPDEHPLGAVVHTAG
VLDDGVIGALTPERLAGVFAPKVDAVRHLDELTRGIDLDAFIVYSSAAGVFGSAGQGNYA
AANAFLDGLMAQRRAAGLPGLSLAWGLWEQAAGMTAHLDDVDQARANRGGVLAITAAEGM
ELFDAAAAAGQPLLVPIKLDLRGARAGAASGGAVPHLLRGLVRAARQQARAASAGDVELS
RRLAGLTAAEQEALLLDLVRTQAAVVLGHTGPGGVRPDTAFNEAGFDSLTSVELRNRLRE
ATALKFPATLVFDYPTPVALARYLREELAETADGAAVPSVSSVAVDRDEPIAIVGMACRL
PGGVADPEGLWRLVREGREGMAPFPEDRGWDLEGLFDADPDNAGTSYASQGGFLQGAGLF
DPGFFGISPREAQAMDPQQRLLLETSWEALEQAGIDPVALKGTDVGVFSGVSTQGYGMGA
DARDVEGYTGTGSAPSVASGRVAYAFGFEGPAVTVDTACSSSLVAMHLAAQALRQGECSM
ALAGGVAVMATPGAFVEFSRQRGLATDGRCKSYAAGADGTGWSEGVGLVVLERLSAARER
GHRVLAVLRGSAVNQDGASNGLTAPNGPAQQRVIRKALAHAGLTPSEVDVVEGHGTGTTL
GDPIEAQALLATYGRDREPERPLWLGSLKSNIGHAQAAAGAAGVIKMVQALRHAVMPPTL
HVDAPTAEVDWSLGAVELLTQARDWPRDGRPRRAGVSAFGISGTNAHLILEEAPEEPVSE
GSAPVGVVPLVVSARSRASLAGQAGRLASYVESGAGALLPAVAGALVSGRAVLGERAVVV
AGSGEEALAGLRALERGESGPGLVSGSGGTPGDLVLVFPGQGSQWAGMGRELLDASAVFA
ERVGECAAALEPWVDWSLVDVLRGDADSEVLERVDVVQPASFAVMVGLAAVWASVGVVPD
AVLGHSQGEIAAACVAGTLSLEDAARVVALRSQAIATELAGRGGMASVALSEAEVTARLE
SWAGRVEVAAVNGPSSVVIAGDAEALDEVLEALSGDGVRTRRVAVDYASHTRHVEDIQAT
LAEVLVGVDAKAPEVPFYSTVTGSWIEEAGVLDAGYWYRNLRGQVRFGPAAADLLGQGYG
VFVEVSAHPVLVQPITEIVDGADSTAQVTGTLRREEGGLRRLLSSMAELFVKGVRVEWAG
VLPAGAGHARVELPTYAFDHRHYWLKPAESATGAAALGLAGAGHPLLGAVVRLPQTDGLV
FTSRLSLRTHPWLADHAVGGVVLVPGTGLVELAVRAGDEAGCGILEELVIEAPLVVPRRG
GVRVQVAVGGPGETGARTVEVYSQREDDGGADTWTRHATGLLATTAHPRDLGGHDFTSWP
PPGAEPVDIGDGYGRLAGDGYGYGPAFQGVRAVWRRGDEVFAEVALPEGQREEAGRYGIH
PALLDAALHSTMLNAVAAVTAAAGDGDADGLELRLPFAWNGLALHAAGASALRVRVAKPE
RDALSLEAVDEAGGLVVTLDSLVGRVVSAEQLETASDTARVDSLFRVEWTEPPPVREARP
SPSWVAVATAEEVATLADDVESGAAAPALAVMDAVGGDEEGAALSLATRVLDVVQCWLAG
TGLEESRLLVVTRGAVPAGGEATVRDPAGAAVWGLVRAAQAEHPDRIVLLDVDATTGAEP
VLGAVLAGGEPQIAVRGPALRVPRLARVSGQTPDAAPVFGPEGTVLISGAGSLGALAARH
LVTRYGVRHLLLASRRGPDAEGVPELVAELREQGATVTVVACDVSDRDQVKALLTGVPDE
HPLTGVVHTAGVTDDGVIGALTPERLERVFAPKVDAVRHLDGLTRELGLELDAFVVYSSV
SGVFMGAGSGSYAAANAFLDGLMAQRRAAGLPGVSLAWGLWEQTSGMAAHTDDLTKSRMS
RRGGLRGMTPAEGMELFDAAVGSGQALLVPAKLDLRGVRAGATAGGGVPHLLRGLVRAGR
QLAHAAGGDEHRQLSERLAALPAAEQATLLLDLVRSQVAAVLGHGTTYHIDADQGLFEIG
FDSLTAIELRNRLRTLTERKLAPGLVFDHPTPGRLAAHLHALMCGEQATTPVALSV
>A0A5B7V4D9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MSAPDEQVIEALRASLKENARLQQENSTLVAAAAEPVAIVSMACRYAGGIRGPEDFWRVV
SEGADVYGAFPDDRGWDVEGLYHPDPDHPGTTYVRQGAFLHDAARFDAGFFGISPREALA
MDPQQRQLLEVSWETFERAGIDPHAMRGGDVGVFAGIVHQDYAPDLSGFEGFLSLERALG
TAGGVASGRVAYTLGLEGPAVTVDTMCSSSLVAIHLAAQALRRGECAMALAGGSTVMATP
GGFVGFARQRALALDGRCKSYAAGADGSGWAEGVGVVLLERLSAAREHGHQVLAVIRGSA
VNQDGASNGLTAPNGPAQQRVIRKALDTAGLTPADVDAVEGHGTGTVLGDPIEAQALMAT
YGQGRDPRRPLLLGSVKSVIGHTQAASGVAGVIKMVQALRHGVLPATLHVDAPTPQVDWS
AGAIELLTGARDWPREGRPRRAGISAFGASGTNAHLILEEAPAEEERPAPEPSGVVPLVV
SAATTASLAAQAERLAAHLEPGAGAAPLTAVAGTLAAGRAVLGERAVVVAGSGEEALTGL
RALARGEHAAGVVTGTGTPGKVVWVFPGQGSQWVGMGRELLDTSAVFAERVGECAAALER
WVEWSLVDVLRGDADPEFLERVDVVQPASFAVMVGLAAVWESVGVEPDAVLGHSQGEIAA
ACVAGALSLDDAARVVALRSQAIAARLAGRGGMASVALSEEDAAARLAPWADRVEVAAVN
GPSSVVVAGDAEALDEALEALDDQGVRIRRIAVDYASHTRHVEDVRDTLAEVLAGIRAQA
PTVPFRSTVTGGWVADAGVLDGAYWYRNLRERVRFGPAVAELLGQGHGVFVEVSAHPVLV
QAITETVDATDADVVVTGSLRREDGGPRRLLTSMAELFVRGTTLDWTATLPAGAASRRVD
LPTYAFDHQHYWLRMADAATDSASLGLTGADHPLLGAVVPLPQSDGLVFTSRLSLRTHPW
LADHAIGGVVLVPGTVYVDLAVRAGDEFGHGLLEELVIEAPLVLPDTGGVRVQVAVSGPG
TTGARTVDVYSQREDAEPDGGADAWTRHATGLLAAPPTAQATGRDVDFTAWPPPGAEPVP
VTDFYADLVERGYAYGPAFQGLRAVWRRGDEVFAEAALPEEQRDEAGRFGIHPALLDAAL
HTNAFARPDDDRKVLPFAWNGLLLHAVGASALRVRVAPCGPDALSFHAADDTGGMVLTMD
SLVSLPVSADQLDTAAADGTRDALFGVEWTELPPAQGDAPPWAPVATAADVTALTASTAT
PPMAVLEAFGADGDDAVLALTSRVLGAVQAWLAGAGSPESRLVVVTRGAVPAGTGVVSDP
AGAAVWGLVRAAQAENPDRIVLLDTDPTAGGPLDAVLGAVLEAGEPQVAVRGMRYSAPRL
ARVTGEVSDVPNKFGSGKSVLLTGGTGSLGGLVARHLVARHGVRHLLLASRRGAEAEGAA
ELVAELVGQGATVSVVACDVSDREQVRALLASVPDEHPLGAVVHTAGVLDDGVIGALTPE
RLAGVFAPKVDAVRHLDELTRGLDLDAFVVFSSAAALMGSAGQGNYAAANAFLDGLMAQR
RAAGLPGLSLAWGLWEQAAGLTAHLSSVDQARMSRGGVLALTPAEGLGILDAGLHMGQAL
LVPIKLDLRTLRTQAAAGGAVPHLLRGLVRTGRRVARAAAGDSGGLARRLAGLPQAEQEA
LLLSVVQGEAGGVLGFSGPELTQGTRGFGDIGFDSLTAVELRNRLSAATGVRLPATLVFD
YPTPVALARYLREELAETADGAAVPSVSSVAVDRDEPIAIVGMACRLPGGVADPEGLWRL
VREGREGMAPFPEDRGWDLEGLFDADPDNAGTSYASQGGFLQGAGLFDPGFFGISPREAL
AMDPQQRLLLEASWEALERAGIDPTTARGGDIGVFSGVSIHDYLESLSNMPAELEGFVTT
ATAGSVASGRVSYAFGFEGPAVTVDTACSSSLVAMHLAAQALRQGECSMALAGGVAVMGS
PIGVLGMSRQRGLAADGRCKAYADGADGTVLSEGVGLVVLERLSVARERGHRVLAVIRGS
AVNQDGASNGLTAPNGPSQQRVIRKALAHAGLAPSEVDVVEGHGTGTTLGDPIETQALLS
TYGQGRDPERPLWLGSLKSNIGHAQAAAGVASVIKMVEALRHGVLPPTLHAQEPTRQVDW
SAGAIELLTEAREWPRAGRPRRVGVSSFGISGTNAHLILEEAPEEPVAEEPVPVGVVPLV
VSARGAASLAGQAGRLAAYVESDTDGVSLAGVAGALVSGRAVLDERAVVVAGTDDEALAG
LYALARGEDASGVVTGRATGSGVPGKVVWVFPGQGSQWAGMGRELLDSSVVFAERVGECA
AALERWVDWSLVDVLRGEVEPGLLERVDVVQPASFAVMVGLAAVWESVGVRPDAVLGHSQ
GEIAAACVAGALSLDDAARVVALRSQAIATGLAGRGGMASVALSEAEVTARLGPWAGRVE
VAAVNGPSSVVIAGDAQALDEVLEVLSGDGVRTRRVAVDYASHTRHVEDIQAALAGALVG
VDAKAPEVPFYSTVTGGWIEEAGVLDAGYWYRNLRGQVRFGPAVTDLLGQGHGVFVEVSA
HPVLVQPVTDAVDAGDVDAVVTGSLRRDEGGLRRLLASMAELFVRGVAVDWSAVLPMTGS
ARVDLPTYAFDHQHYWLTPAARATDAVSLGQAAADHPLLGAVVRLPQSDGLVFTSRLSLR
SHPWLGDHVLGGAVLLPTTALVELAVRAGDEAGCGVLEELEIEAPLVVPERGGVRVQVAV
GAPEEDGSRAVEVYSQGEDETWTRHAAGALSADGPAGGGGPRFDFTAWPPSGAEPLGTGE
FYADLAERGYAYGPVFQGVRAVWRRGDEVFAEVTLPEEQHKGAGDFGIHPALFDAALHAG
VFADPGDGGPGDLQAPRQPLDWHGLVLHAAGASALRVRLVSGGPDTVSLEAADETGGLVV
TADSLTWREMSVDEGETADTVVADSLFGVEWTELPPARGAGASLSWMPVTAADEVATLTE
EVASGAAVPTAAVLEAFGGDGEGAVLALSARVLEVVRAWLAGAGVEDARLVVVTRGAMPA
GEGAVTDPAGAAVWGLVRAAQAEHPDRIVLLDLDPGSGDGDGTGPVLDTVLGAVLATGEP
QIAVRGGAFAAPRLVRQPAQGAEGEALFRPGGTVLVTGGTGALGGLAARHLVTRYGVRHL
LLASRRGPDAEGAAELVAGLAELGAVASVVACDVSDRDQVKALLTGVPDGHPLTGVVHTA
GVLDAGVIEALTPERLERVFAPKVDAVRHLDGLTRELGLELDAFVVYSSVSGVFMGAGSG
SYAAANAFLDGLMAQRRAAGLPGLSLAWGLWEQTTGMAAHTDDLTRNRMNRRGGLRAMTL
TEGMELFDAAMGSGQALLVPARLDLQGVRADAAAGGAVPHLLRGLVRPGRQLARAAGGGD
ARRRLTDRLTGLAAAEREALLLDLVRGRAAAVLGHAGPSDVRADLAFNEAGFDSLTAVEL
RNRLREATGLKLPATLVFDYPNPLALARHLHRALLPDGDAGGAASGQEPDEARLRHALAS
VPLARFRAAGLLDALVELAAAGDGGPGTGTTDGADGADGAEGADGERAIAELDVDDLVHL
ALGD
>D3VCB3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / CCUG 14189 / LMG 1036 / NCIMB 9965 / AN6)|TrEMBL
MVNNVTGLEVAIVGMAGQFPGADNVHDFWEMLCDGKEGISRFTQETLENNGISPEEYLNE
DYVPAKGIINKPYHFAADYFAINHPDAEKMDPQTRLMIETCWQALNHAGIDAKDYPGEIG
VYAGAGNQWSWFNTLNTEFNSSAEQFHVATLNDSAFCSRISYLLNLRGPSVTIQTACSTS
LVAVHTACQALQAGECDIALAGGVSVTHPHQAGYRYQEGMINSIDGKTRVFDEQAGGTVF
SNGVGVVTLKRLTDAIEDNDRIYAVIKGSAINNDGNDKISFTAPSALGQEKVIRAALNVS
EIDPASISYIETHGTGTVLGDPIEIAALDAIFHGQQSCAIGSVKSNVGHCDTAAGVISLI
KLSLCVYFKTLVPSINFEKANKKLALEKTPFHVNTQTKPWVTQNNTPINAGVSAFGVGGT
NAHLVLQEFSERTESVSAEHLNYQELPNRIEFKPAIKKETASAFNEEQDNEEQEVSVDFA
EKIDINAILKEILNVLTAYFPNKNISKDDNFFDVGASSLDIVQLHEKINAHYAIKLSIND
LYRYTTCQKISEKIYDVINEMPRKTTRKLKKVASGKTSNRIKTTHHDYPENAIAVVGISG
RFPGSHNVREYWKNILSGKEGISFFTDDELIDAGIPEYIFKNKHYVRAKGIVENALDFDK
TAFGYTMREAQYMDPQFRLLHEITWEVLDDAGYGNPKYRPVTGLFASSGSNYEWLDRVKE
EVKDTTEQFSIGLLNDREFLTTRIAYKLNLTGPAVTVQSACSSSALAITLACQSLRVNQC
DLALAGGVSITVPVKSGYMYVNGMVNSADGHCKPFSEDASGTVFSDGIGMVALKRLEDAI
ENNDHIYGVIAGYGVNNDGYEKAGFTAPSANGQAACIKQSLAMAGISANDVGYLEAHGTA
TLVGDDIELEGVKSALSVADDNPSICHIGSVKSNLGHTDSAAGVAGFIKTLLTVKHKKIP
PTCHTEKNDHGLLQGTRFRLINAATDWDNNNDIRTAGLSSFGIGGTNVHITIQSILEQIS
SEQDRPELITLSSKSKAGLIKTAETLGQFLNADTHTKSLSDIAYTLQIGRGEHEYRTSFV
IDNVKELKNALLHVKETNNIAEISFDQTPGIVFMFPGQGAQYINMARDLYNELGIFRTLL
DECHEYLFERFGINLLALLYDEKNQDSIEKLRNTQFTQPIIFAISYSLAKSLEELGVEAK
AMIGHSIGEYVAAAMAGVMTLDEALELVAVRGLIMQECEPGAMLSVSAGREEIEPYLTDE
VTLATVNSSTACVIAGPQTEVEKVQLVLADKNYRTRLLETSHAFHTAMMRPAVGKFKQAL
KKIKWRKPNKAYISNVTGQWITAKQANSIDYWVAHLCETVEFHQGIMTCLEQPDLNAFIE
VGPGRTLSTFVKQIIGTNTDISVINVMRHPLEEENDRAYLLKLLGQLWMKGYAINWSVIY
QDVKPGRVSLPGYQFISEKMGPGNLPAGSNQAEKITETRIQKNTISDWLYGEIWQDALLP
DKSNQSEVKTALCFVPNMEWCEPLSRHLNVDEKSIRFVLSGDDYTSVNNVITLAAGEVSH
FEKLFHELKENQLQPDSVIFAWPLSGHRDLKNTWFSAITLLQAWATIGNMGDFRLLLVNT
EQPESGMLKGLVKVITQEVSKCHPRLVQINTTESIENTCEILTEELLATDGRFIVCRTDG
RCSEQVYERLNVEPQKKHSLLKQQGTYLITGGLGDLGLLFAEYLLKEYQATVILSGRREL
PDRHEWQQATQSDLSTTNLLQQLNKLADLGRGNVVYYPANVADKSAMQRLLQTIDEQHGV
LNGIICAAGVTEGDSFQGINRITLDACSPQIETKVEAYKILAELTEHQPLDFCLLCSSIA
SMLGGLSFSAYSSVSAFADAFARQQNQQGKPWISINWDGWVFERNDSGDALGSSLSQLLI
EPDEGIQILERVLQSPLRGQIIVSTGDLNQRFEQWVGSHLKAFDINKISKSHRKTISKDQ
ITETIISVWKDFLKITQINREDNFFELGANSLDLVQVNKRLTDALDIDISVVDMFSYPTS
ELLADYITSQYGTVSTNDSQYEQPDHSDESAYVAEYLVKPDTVFDKHIAIVGMAGKFPGA
EDIYEFWDNLCYGKESISIMSKEELIESGIDSDLLDDPNYVRAKGIMPHSGEFDAEFFGY
TPYEARQMDPQVRAMHICSWQALQDAGISPKNNKLKIGLYTAASGNLPWLAQAMATAEGS
AGQYSAMVVADKDYMSTSVSYKLNLSGPSMVISTACSSSLVAVNEAIKSLRTGECDVALA
GGVSITLPIKAGYLFEEGMIYSKDGKCRPFDIQANGTVFSDGVGVVVLKPLKQAIADKDN
IYATIIGSGINNDGGMKVGYTAPSTKGQVDVIQAALRDANVSSESIHFVETHGTGTNLGD
PIEFNALKQAFSTDKKSYCRIGSVKSNIGHLNFASGVTGLIKAALSIKNKVLPPTLHFAR
PNKEMDIANSPFMVNNQYTELHDNKYPIRAGVSSFGLGGTNVHLVLEEYRADQNKLSGKN
ANNRLPLILSAPDEKSLQSYKKQLKQVIQSDNQKLNISDFTYSLMQRETMASQFIAVVNN
RDELINALSSTEKDNINLSRGIKRKVVFLFPGQGSQYIAMGQDLYKNNMLFKQWCDKGFV
IAKDYCTTDLKALLINGSQEQPIYETEFVQPLLFIIEYALAQVLQSYDITPDAMIGHSLG
EYVAATLAGVFSYEDAIKIICIRGRYMQSTETAAMLSVMASSDKVKEILPENLDIALDNS
SELCVVAGSDEAMTQFEEICHTESIKTKRLEIKRAFHTRYMDPVLEEYGQALKGITLKKP
QIDFISNVTGEWVDHKRVTESDYWVDHIRQPVRFRQSIATALENEHCLFIEVGPGRGLST
LVQNHSDYNANHACLSWQGHKTKGMSHHHELIEKLAMIALYGIRVNWQQEINEQQPELIH
LPPTPIRGKEYPTDIKRLQALFSGNPTSVVEETEKEEKINTNPISRGKVPESAIDQLGAI
WKLILGIDKIENSDDFISLGGSSLSAVQVIAKAKEINLPININMLLSGKTLLEINQLLGN
ENNIEYKTQRWTFNEKFSPEFYPEYASCLYSAVREKLKHEHQLDCSDALMLVSDGSPLLG
IVLQQCEKETQLSHQEVNFGHILGWPALDDSYSFSYAKKFFDDYESYRHYCEKELSLGHV
VIVTGSDYYLPFSPSYGLSEAEYIERPLFQDIVLDDEVIPHAFVLVGKTDSGYQVYDGSF
QYFGEITEQEFEKTVIGFRGLDFMQSHEVFKKSRPYLVITVNCDGDFPDSEAQQKIILNN
LINDFRKEEEIKYPENEFSCYIGLAAIEKLIETPALLTNSAVADLEEIFVRWRDQISSLK
RFLMIARSASAIQLESSFSLIQEKMEDLIVSCKDHDNDGNKVNCLTQIKSGLDSVINIIS
E
>B8MV60|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MGSLSSARESAQRITFFGDQTVDTLLCIKDLANRSHQLPILRRYLREAADKLQLLLSQIE
LGDYECYRNFETIVELAEIYSKQDGTYEPIGCALWTISQFADYLSRSETDPSILTLSDSA
AQPTYVVGVCGGLLLGAAAATARDINELLDIGRKLVDVSFNLGVAQWKRAMDIEGKPGRW
AVAIVNVPPKQIRNIITAFNEDMAIPKHRQFYISFLAKGWAAISGPPSIFPELWEYSSTL
SSASKMDLPLGTPAHAAHLRSLNIEELIGSGSVLDLPVRQDRLVISTSTCKPFESQTFGS
LLSSSLHDITGETLHIAGVNDYVASCLSRETLVQVSSFGPTSQIGSFKKALEDSGLKVDL
DLSVPESKTPNLLKNPDARDGSNMIAIVGQSVRLPGSDDVKTFWENLKAGQTFESEIPPS
RFDLQNYYDTTGAKKSSVTTRFGHFLDRPGLFDCRLFNVSPREAKQMDPIQRLLLMCSYE
ALQTAGYSPDSSLSTNRMRVATYFGQSGDDWRQGRASQDVDIYYIPGTIRSFAPGKLNYH
YKWGGGNYSVDSACAASTTSVIMACNALLGRECDMALAGGGQLHLEPENYAGLSRAGFLS
KTTGGCKTFREDADGYCRGEGIGVVVLKRLEDALADNDNVLAVVRGADRNYSWDASSITH
PSANAQATVIQRVLRNTGVEPADIGFVEMHGTGTTAGDSVEMKTVTTVFGSRPKDNPLYI
GAVKANFGHGEAAAGITSLLKAVQMLGQKTIPRQPGFPGPKDPTFDHLDAMNIRIPDSSF
PFPTPTRPFSQDGKMRILVNNFDASGGNNCVLLEEAPDKNVSQIQDPRQYYTVAISARTT
KSLQKNMERLSDYLVKHPDTPVADVAYTSTARRIHEDLKRSYTVDSTESLVGLLQADLKK
DLTGIRPATPRSVVFAFTGQGSQYSGMTKQLFETCTPFRESVQSLHDLAVWQDFPSFLNL
FTDDVTDEISASPIQTQLAIVVLEMSLANLWKSWGVEPDLVIGYSLGEYVALYVSGVLSA
HDVLFLVGNRAQLMDERCEIGSYSMLAVQASPEDLEEPLKAYPTSNVACRGAPRSTVVSG
PSEDIAKLHAELKEKSISGTILNVPYGFHCAQVDPILEDFRDLLDRVPFSKPRIPVASSL
DGVIVTDDDVFSPSYMVRQTREPVAFVSALKAIETSHLVDNTSLWVEIGPKRVLNSFIKA
TLAVDHDRLLHSVDEKASNWRTIATAITACWQGGVSIKWQNFHRQFTKHLRLVDLPTYAF
DLKDYWIEPAAPIVQQRSAAEPLRQVAVPAVPGFPTASLQRVREERIQGDNAAVTFESTL
SHPDLMGLIRGHQVNGVDLFPASGWWDMAYTAAKYIHHRIQPSRGAAPGLSMLDCSITHP
LMPSASEDQQKLVIIVAKKQAGSSVVEVSFKSQEKSVEQDHGSCKIRFESKADWEAEWSR
SAHFIKAAKNNVVTNATRPDGNGHKLPKPVVYTLFSNFVNYSGDFKGIQQVYLNADFQRE
VVADVVLPAGMYNFNLNPYWSDALIHACGFMLHSDPDLPTQDCFLFNGFEELRFLMDDLL
PGVPYTSYVFMHDTNSQEVPAKRTRNVTGDIYIFQGEKIVGTVQGVVFQRLTKRILTTIL
GKSQDHHNSNEVRNGNATTTHTNPPAHATTQSFFAPPGIKPAVAFSSAPATVGEETAEAV
IAKILTKTGANRASLSESTTLGEIGLDSLEWIELVGVFRSALDIEVPASFFFEYPKVLRL
RQAIAELPLEGEKEESGSSSPDSPYGMLTPATGRFTPITASRSTHNSDGPANYANIVLDI
VLSQTGFDKDDVLPSTRFDDMGLDSLCTMEVVSLVREQTGLDLPASFFHHHPTVADVRKN
LGPNTEDKSKDSVKASASIAVSEPATELVVVHHPGNSPAPESLPIIDEDLKDYHCDFFLM
QGSSDSAEIPMFFLPDGTGYPAVLLKLPPVFKGDNPLFTCKSPLLHRAEGREVACTIEGL
ALSYAEAIRRTRPHGPYLLAGYSLGAAYAYEVAKILADAGEIVQGLLFVDFNMAASVGLE
HRERKPVPTNLNVGVMEQVGWMNGIHNDEKNFHIPPAPPKIKFHALSVFKSLTRYFPKPM
TPSQRPRNTYALWAGAGMEDLLGPSNAGFLPEFGIIDWQMGSRRENNGPAGWENFIGGPV
RCATVPCDHLSIMMSTDWVGTTANIIKDLLEDALSNPGTP
>G0Q9U3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MTTSTDKLVAALRASLTEAEELRRRNKELTAAQSEPVAIVGMACRYPGGVRSPEDLWNLV
ADEADAMSAFPADRGWDLDALFDPDASRGGTSYVREGGFVHSAGEFDAEFFHISPREALA
MDPQQRLLLETAWEAVERAGIDADTLKGSRTGVFIGSGTPGYGAGLKDAPEEVQGYTLTG
LATSVVSGRVAYAFGLEGPAVTVDTACSSSLVALHLAVQALRQGECTMALAGGVTVMSDP
GVFAEFSRQGGLSPDGRCKAFADAADGTGWAEGVGVLLVERLSDAVRNGHRVLAVVRGSA
VNQDGASNGLTAPNGPSQQRVIRQALDNARLTVDQVDAVEAHGTGTTLGDPIEAQALLAT
YGRRRSTERPLRLGSIKSNIGHAQAASGVAGVIKMVMALRNGTLPKTLHVDRPSTHVDWE
SGAVSLLTEAEPWPETGESRRAAVSSFGVSGTNAHVILEQAPSLPDPEHPAGPPSSVLPW
IVSAPDPQQLRTVADRLRAHVERRPELTTAATAATLASHRTFLDQRAVVVGADRSALLSG
LTSVAAGEPHAAVVTGTPNGPGKAVFVFPGQGAQWSRMGLELADAFPVFDKRLRECADAL
APFVEWDLRTELAGGLGQVDVVQPASWAVMVSLARLWESFGVVPAAVVGHSQGEIAAAVV
AGALSLEDGARIVAERSRVIGERLAGRGGMASVALPAETVRERVAGFGERLAVAAVNGPS
STVVSGEPAALDELLAALEGEEVRVRRIAVDYASHSSHVESIREELLDVLAPIAPRSATV
PFYSTVTGGLLDTEQLDAAYWVRNLRQTVEFEATTRALIADGLSAFVECSAHPVLAVGIQ
ESGATGAVGSLRRDDGGAHRFVTSLAEAFVAGLPIDWTPLLGGAEPAELPTYPFRGTRYW
LEAAESDAPEAEPVDAAEAGFWEAVEREDAASISTSLGLDLDGDGLSALLPALASWRRRS
REESVIDSWRYKTAWRPVATSEAVLSGTWLLVVPASPSDPAGVWADTVETAVRDAGAATL
RVALHPGAERAEHAALLSAARAGVTDVVGVLSLLALAEDPLPGLPSTPAGLAGTLTLVQA
LGDAGIDAPLWCATRGAVSTAPSDPLTSPSQAQVWGLGRVVAEENPHRWGGLVDLPEHPD
ARALARLAAVLGGTDDEDQVAVRRSGVLAHRLVRAPWGDGREPRAWRPEGTVLITGGTGA
LGGHVARHFAAQGAPHLLLLSGRGPDAPGAAELERELTGLGARVTLVACDVADRDALARV
LDSVPDDLPLRAVVHTAAVLDDAIVDALTPAQLDRVLHVKARGAHHLDELTRDAELTAFV
LFSSFAGTFGVAGQGNYAPGNAYLDALARARRSQGLPATSVAWGHWSGGGIASGTAEAQL
RRRGGSEIEPHTALRALQHVLDHDETVVALALIEWDRIAAGAANDAESRTRPFLRELEDV
RRLLRSARNEPTGDDTGGGLPAARDLAALPRAERERALVDLVRTHAAAVLGHASPDVLDA
ERPFRELGFDSLTSVELRNRLGAATGVTLPATVVFDHPTPRDLAAHLRGTLLGDETTGTD
GGPDVAAPAPASGAEADASDPVVVVGMGCRLPGGVDTPEDLWQLVVEEREAVGGLPDDRG
WDVEALVTAGIDVPGMQYVRQGGFLREASRFDASFFGIGDDEALAMDPQHRLLLELAWEA
LERSGTAPGSLRGAPVGVFLGTFSQGYWTGMQEVPEATRPYLSGGISPALAAGRIAYALG
LEGPVLTLDTGCSSSALALHLACQSVRSGECEQALAGGASVLANPAVSPGMGIGAASDGR
CKSYAEGADGTGWGEGAGMLLVERLSTARARGHRVLAVIRGSAVNHNGTGNGMGAPNGPS
QQRVIRQALANAGLTPADVDVVEGHGTGTALGDPIEAQALMAVYGQDRDPAQPLWLGTVK
SNIGHPQAASGVIGVIKTVLSLTHGSLPRSLHSDEPSSHVDWETGGVRLVQKSAPWPETG
RPRRAGVSSFGASGTKVHVLLEQPAADDAEPAARGSRTGGLPVAPVVLSARGAEALREQA
ARLRAHLTARPGTDVADVAWTQAVGRSAFTDRAVVLAADRDALLEGLAAVERGQEGDSVV
LGTPATGDRPVAVTFGGAPVPPGAARRLHAALPAFADALDALCARLEPLLEQSPLDLLLA
ERAESPGEADSPEPGADAPATPGTAGTGVAGTGAVAPATAHAASYAFGLALFRQLSSWGV
RPVATGGQGPGAVAAAVAAGALDEAEAARLVLALATGEHLEAAVAALTPPPSGAALPPVG
TKGVEPGSAAYWAAAWDGGSGAAPAGAVVLDLGGAPSPEPARDRVALPVTGDGTADAVPA
ALARLHTHGAAVAWDRVCGEAAHRLADLPTYAFQRSGYWLRTPVHLFTAGAAAGAVGVTE
AGGTAAG
>F8B163|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Candidatus Frankia datiscae|TrEMBL
MSTSTHRSPQARTSGASRAGAARVPGSSRDLVVAITPFTEPDARLVAAVARAGGLGVLDL
GRDAAARAALADAARWSRGPFGIRVPVGCATSPWELPPEVDTVVLATGPAHGGRDGEWDV
TTAAVGRRRVLIEITSVAQAQVAAAAGADGLIARGGESGGRVGDLTTFTLLQHLFAADGL
DLPVWAAGGVGPHTAAAAVAAGAVGVVLDVQLALVREMELPAEVAAAIRGMDGSETTVLA
GHRVYVRPDLPVVGLAGQQFAGPGQQVDEDTDDDAVAYRLGARDLREQFLPVGQDGAFAA
PLADRYVTASGVVTAVRDAIEAQLAAAVRLAPLAPGASFAADRGLRVPVAQGPMTRVSDR
AEFARAVADGGGLPFLALALMDGDEARALLEQTRALLGDAPWGVGILGFAPPEIRSAQLD
AIGEIRPPCALIAGGRPSQAASLQSAGVDTFLHVPSPGLLGRFLAAGARKFVFEGRECGG
HVGPRASFPLWESQIAGLLAYGEQVSVASGRSAASAFFEGLHVLFAGGVHDERSAAMVAA
AAAPLADRGARIGVLMGTAYLFTAEAVNSGAILPGFQRTALDCDGTALLETSPGHATRAA
RSPFVTTFAGRRAELLAQGLAPAQVWEELEQFNLGRSRIASKGLRRDRGRLVSVDEDVQR
NDGMFMIGQVAALRSEPTTVAALHAQVSEGATQTLVDRLAALGIDPDSDIPDSDIDTDRD
IDADTDVGAALGQPARPGATTQAGARARTGARARGRGRGRRRETARPLDVAVIGMACVFP
GAADTAEYWANVLGGVDAVTEVPRSRWDADLYHAPVQTPDQRASGGPDSGRGGGRVPSRW
GGFLPPVPFDALRFGIPPKSLGSIEPGQLLALEVTARALRDAGYDNRPFDRSRTSVVFGA
ESGADLAAAHGFRSAYPAFFGPVPPALAERLPTLDEDSFPGMLANVIAGRVANRFDLGGV
NYTVDAACASSLAALDTACKELVGDTSDLVLCGGVDTHNSIHDFILFSSVHALSPTGRSR
SFDAAADGICLGEGVAVVVLKRLADAERDGDRIHAVIRAVAGSSDGRALGMTAPSRAGQV
LAMERAYARAGISPADVGLVEAHATGTVVGDSTELASLTEVFAGHGARRGSCAVGSVKSQ
IGHTKCAAGLAGLIKTARALAVGARPPTSNITRPNPSWDAGSSPFFFDTAARPWAAPASR
RHAGVSAFGFGGTNFHVVLSAYDGAPEPTHGLDAWPAELFVIRGTDRAAACRTLDRLAEL
IRVNDGAGRPWKLRDLAATVAVKRGGAVRVAFVATSLDELADLVKRARAFTHDPKAGIFV
AGGDRGVAGQARAGRATLAGTADTAPAPAGKQGTGGAEEEEAEEGKIAFLFPGQGSQRPG
MLAELFVAFPRLRHLLERGEKWVPAMFPPAAFSRADTDARHAAITDTRTAQPVLGIAGLA
MHEILTGLGVRPDHLGGHSYGELVALCAAGAVDIDDLLPLSEARAAAILDAADAFAAASA
TADPSGAPATGVIVGPAVGADPTPVDADTTTISSDTTTASGDIDPVTADAGTMAAVSAPA
WRVREVLDAATPDPVDGPAGPGDAVIANHNSPEQTVISGPTPAVDAAVRRLAAEGLTARR
IPVACAFHSPVVAAAAGTFAAELDRATIIPPSRPVWSNTTARPYPDTADAIRQTLAGQVA
QPVHFVEQIEAMYAAGVRIFVEAGPGRVLTGLTSRILHGRPHTAVATDVPGEHGLCRLLL
ALAELAAAGVAVDTTPLFTGRDAQVVSAANCPRRPGWLVDGHLVRTSDGRHLPGGLVPAD
RLTRLPVSEPPSWAASPAVAELPTVIVPPSVGNTDAAVIEFLRTTRELVAAQREVILNYL
AAADRTSALPPAALTRAEAALPPGTLDHVPLSDSHEHGPFPAVDNHVVSPTPADHAAPLP
ASADQPWPPGQPVGHGDAPAVVVSERPVSREPDVVLGAVVEVIVSATGYPAEMLAADLDL
EADLGIDSIKRTEILGTLAEQLGLGLPTAREAGTTEGGATMDVGAAGGWRAGTAEAGTAE
GSLADEVVEELAAIRTIRGIVEWIVTRSDAGPAADTYPAADAGPATYPDPAASVGPAVGP
GNAVGPGSGPELAAVRGPVTIPGSGIVVEAASVADAGSGPAVPASVSRQAGGRPSERFVR
PPGPRDPADSAAALRRFVVEVVPLPSPGTLPDLLALAAAGTRPGPGPLAGSRFAVVEGGL
GIGLALATLLEQQGASVRMFSVDDASLADQLAGGCRGGRCLVGVVRGPGRATGPARRVRP
DPGRGCRRHPASDHRDRWWGQLRSRGGRRARPSCGDGRFHAHARPGGAGRGGPRGGPRSE
GGADPARRLPAHGVPHAGRPVGDRLPARRPVDSPGGAGRDPRCRCAPGRLGGSGGPGWPG
EPGCSDAPGRRAVVGLAVARRCCFRTAAPGRRRAGGTRPELRRPAHRWRARDHRQGRPRA
CPGHRLRDRADRPDAAAGRRRGSGDGLRGGRASAAPRPDRRRPAPAHRGRGPCHPPARRA
GGAGHRRGPARERVLRPLSRRRRAGSGRAARGRRDDLRRPWPARRGRPRRRRPRGQTAAG
EDGALVRAGVLDQGRRRPDAGRRAAARPRLPGALRQRVRGVRQPGADRLRRRQRRARHLR
PCLGEAAARPCRVPGLGPVGIARLCGPCGR
>A0A498Q5I2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium attenuatum|TrEMBL
MATHRLPDDRVPILLSAHEAELIGQDAAAILNYLARLGAEAADVTPAVAATLLRTRRVRR
HRAVVRAADRGELEAGLRALAVGDRHPLIARSSENAKTRTAFVFPGQGNQWPAMGAEAYQ
RLPAYRAEADRCAEAFAATGLPSPLSYLLAGSSASSSANSDEGWSQIDIQGAQFTHAASL
AQLWRSCGVLPDLTVGHSLGEAAAAYVAGTITLAAAVAVVAARATVVGRLSGRYGMAVLS
MGADQAARMIAEAPGWLEVSAVNSPSSTVVSGDGDAVAAIVRLAEKDGIFARELTVDYPG
HTSKLESLRETLSDLLPASEFLDAPVEFVSSARSDVVTPDTDFTGYWYQNLRNTVRFDRA
VATAVQRGAGTFVEMSAHPSLLYALAELAEDALSVGSGRRDEPVVEHLSANIAAAAVANP
GYRWSDVAGVGDQSPLRGFPAAPMRAIHLWATPEPLPPAPGTSLVVAYERWERSQPHQQR
QDSLADRAPTVAIVTPDADGLDALTRRLTEAVAAHQECELTGPEEAEVAVLVAPALMHPD
PTAATDQIRGSTGQLDYRRAIGPRCRRVWLVTVCGEQLDASAPAALPAQSALAALHRSVG
FEFPDQTFAHLDVPSRDIDEAAAHRCVDVLLGDHSEVALRIDDSGTGKLGCFVRTLCESA
AAAPQGVDAAALDHVVITGGNGTIGLRYARYCIEHGARRVTLLSRNGVGKAELDRLAEGY
PAQVHAPACDITDADALSAVAVDYAGDGASLLVHAAGAARFAPHDQLGDQELADVFSAKV
TGLARMTDVWPLRRDGRILLCSSVSGVWGGYGHGAYAASNRLLDAVAAQLRSDGLDCVSV
RWGLWQGTTIAGVDEVARIERSGLIAMDPDVAIAASLGRHQGDPLILAADFDRLRVFFES
QGAALPFTTAATERDSDSAAPGESPEQRPISELVRAEIASAFSLDGPASVDLNAALVDLG
ADSMLALDLRDRLRRWTGQSVPAARLLGGITGAELIEILQSAPRADGSAGPAPAAQPDST
ADPERPDQRRERLKSSRD
>A0A1D2IK58|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. AVP053U2|TrEMBL
MTGSPDLAPFPQLPEPVAEQSERQNDPIVLVGAGRRDRMADAVRAAVAQAGIDPAVLRGT
RTTLITAASAGAAGRLAAALRLTGSTISLDTREAPTLLALHLAAQALRAGDTSYAVVGAE
LPDKTCALILARQSAATAAGAASQAIVRTTTADHTTTADHASTPDDHGSPARETPHAIRL
LTADMTQAPAEGFPGLLATLHDDTPLRPTAVTEHGSDATTVLVLLDQPQDAAPAAPLPWV
VSAPHTRALRATAATLAVHLDATPAAPADVAHTLLTTRPDRRRAAVVGADRATLTDGLRA
LATGVDAPHLVHGTATGSPRLVFVFPGQGSQWPGMAAELLETSEPFHDSVHACADALAEF
VDWSLLDVLRQAPDAPPLHRVDVLQPTLWATMVSLAAVWRSYGVEPAAVVGHCYGEIAAA
QVAGALDPRDAARLLAHRSRAWLRLVGKGTVISVATSGQDITRRMAAWPDSVELAALNGP
RSVALAGPPDVLDGIVADLTDQGIHAKRIPGVDTVGHCSHVEVLRDHLLDVLRPVSPRSA
AVQFYSTVDGAERDTTTLDTDYWYLNTRSQVRFHQAVRNLLAAGHRSFVEVSPHPLLGAS
IEDTAAELGIHDVAVVGTLRRGQGGTRRVLTSVAEAYVHGIDVDFTPAFTGTTPSRIDLP
TVEDHGIEGHGADGGETWTDRVRALPDEQRDEALVDLVCRTVATVLEADPADTANAIAPD
TAFKEMGLGSLSAVRLRNGLREATGTHLPATIAYDHPTPAALARHLAMTLFDATGAAPVA
PASGRDHEPIDAETALLTALEQADEALERLRTPHARTPRQETDRRIDELLQSLTDKVRRM
RQADAVDDADDSATDRFAAATDDEMFALLKERFGIS
>A0A1Y2NHZ3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces platensis|TrEMBL
MTNDKKLVEYLKQATIDLRQSRRRIWELESEPIAIVGMACRYPGGVASPEDLWTLLSEGR
DGMSAFPEDRGWDVEGLYHPDPENPGTSYVREGGFLQNAAEFDPGFFGISPHEALAMDPQ
QRLLLETAWETFERAGIDPGTLRGSKTGVYAGLMYHNYAARVIDVPDDIASFMSTGAVSS
VVSGRISYLFGFEGPAITVDTACSSSLVALHQAVLALRAGDCDLALAGGVTVMATADTFV
DFSYQRGLAADGRCKPFAAAADGTGWGEGVGLLLVERLSDAQRNGHPVLAVVRGSAVNQD
GASNGLTAPNGPSQQRVIRQALANAHLSPSDVDAVEAHGTGTTLGDPIEAQALLATYGQD
RPADRPLWLGGIKSNLGHTQAAAGVAGIIKMVLAMRHGVLPKTLHLDAPSPHVDWSAGAV
ELLAEARDWPAAERPRRAGVSSFGISGTNAHVVLEQAPADERAESGSAPAAPVASDPSGL
VPWVLSARSRQALTAQAAGLAAFVDQQPELNPVDTGFSLVTTRAALDHRAVALATDRAGL
RTAVSALATGDAAPGVLTGLVSDGKLGALFTGQGAQRLGMGRELYETYPVFARAWDEVCA
ELDGLLPRPLTEVVRGGGELLDQTQFAQAALFALEVALYRLVESRGVTPAVLLGHSIGEV
TAAYLAGVWSLSDAAQLVAARGRLMQALPTGGVMVSVRASEDEVAPLLEGRDLVGIAAVN
GPESVVLSGAEAEVAQVVAALEAEGRKVKRLRVSHAFHSPLMDPMLAEFRAVLGQLTYAD
AQLPLISNVTGALADSAELRNPEYWVRHVREAVRFHDGMRAAHAEGVTTFLELGPDGVLS
AMGQDCLAEDGVFVPTLRKDRPEPEVATEALAGLWVRGVPVDWQSMLADGRRVELPTYAF
QRQHFWLAGDAGVGDMTAAGLGAADHPLLGATVTLPDAVVLAGRLSLATHPWLADHAVLG
AAVLPGSALVELAIRAGDQVDCDLIEELAVRLPLVLPERGGVQLRVVVAEPDEDGRRELA
VYSRLEESPEQSWTVHAVGVLAAGAGAGAGTFGEAVWPPAGAEALSVEGCYDALGAAGFH
YGPVFQGVQAAWRRGDEIYAEVTLPDEVTADAAKFGLHPALLDAALQPALDGLRLPVSWN
GVRLHAVGATALRVKLSRAGDGFALLVADEAGGVVASVDAVRWEPVVPEQLTTSVPGEHH
DSLFAVEWVSLPELPEASEAEGDDGLVLLHPSVAGESASVPDGVRAVTHQVLEQLQRWVA
DDRNADDRQANARLVVVTRGAVSVAGEPVDLVMAPLWGLVRSAQSEHPGRFVLVDVDDHE
QSTAAIHAAVATGETELALREGALSAPRLTRLEPSAPSAPSGPPGQAVLSSTGTGTGTGT
GTGTGTVWNPEGTVLITGGTGTLGSLIARHLVTAHGIRSLLLTSRRGPDAEGAAALLEEL
TALGAQVEIAACDAADRDALAELLAGIPADAPLTGVVHTAGVTSDGTLGSLTRESLDAVL
RPKMDAAWNLHELTQDADLSAFVLFSSAAAVLGAAGQGNYATANTFLDTLARHRRNHGLP
GTSLAWGLWAETSEITKQLSDTDLRRMARGGLVPLTAEEGVALFDAALTTDTALSIPIRL
DLRALAASGEVAPVLRGLVPVRRRAATAGVGAGNALRDRLIGLPQADQDRALRELVTAQV
ALVLGYAGSGAVEASRAFKDLGFDSLTAVELRNRMDTATGLSLPATLLFDHPTPAALVRF
LREELLGGQTATTVVRSRGTVDDEPIAIVGMACRFPGGVASPAELWDLLARGEDAVSDFP
GDRGWDVERLYHPDPDHHGTSYVREGGFLRDVADFDPGFFGISPREATAMDPQQRLLLET
SWEALEDAGIDPATLRGADTGVFVGTNGQDYGSFLAHSSAEVDGHLATGTAGSVVSGRIS
YTFGFEGPAVTVDTACSSSLVALHWAIQALRSGECSLALAGGVTIMSTPMEFIEFSRQRA
LAPNGRSKAFAESADGAGWGEGVGLLLVERLSDARRNGHPVLAVVRGSAVNQDGASNGLT
APNGPSQQRVIRQALANSGLQASDVDAVEAHGTGTTLGDPIEAQALLATYGQGRPEDRPL
WLGSVKSNIGHAQAAAGVAGVMKMVLAMRHGVLPKTLHVDEPSSHVDWSSDAVELLTEAR
DWPESGQLRRAGVSSFGISGTNAHVVLEQAPDEAPAEPVEQARPGVLPWVLSARSERALL
AQAGRLASFVKDREELDPVDVGFSLLSTRAGLEYRAVVLGADGEGLLDGLRGLAAGVDPA
GVVRGATGTGAGSRVALVFPGQGSQWLGMADELLASSPVFAGRMAECGAALSEFVSWKLD
EVLSDEDALARVDVVQPVLWAVMVSLAAVWEDCGVVPSAVVGHSQGEIAAACVAGVLSLR
DGARAVALRSQAIGRVLAGRGGMVSVAASREAVQERIAKWGERVSVAAINGPTSTVISGE
PDALQELLAECGEQEVRARQIPVDYASHGPQVEELREELATVLAEVRPGQGRIPFYSAVH
ASPLSGEELDAAYWFENLRNPVRFEEAIQALLADGHGVFVECSAHPVLTPGIEDTAQQES
GSPVVVTGTLRRDEGGWPRFAHSLAQLWAHGVPVDWSTLLPTGRRIDLPTYAFQRQRYWL
SASAGTQDAAGLGLQPVEHPLVPAAVSMAGTDTVVLTGRISAATHPWIADHTVRGVTILP
GTGFVDLAIRAGDQVGCPRVEELVLEAPLILSDQGGVQLQVSVGAPDGQGRRSVTVHSRA
DDALDGEPWTGHATGLLGPDTADGSGTGLDVWPPQGATPVDLDGIYDQLAAAGVDYGPVF
QGLREVWRQGDDLYAEVTLPQDQRDEAERFGLHPALLDSVLHALSWSPLAEQEGGPWMPF
TWNGVSLFATGATTLRARLRTAPTGAVTLDIADGLGEPIASVDALRLRAVTATALTGAAP
RDTLFRPEWTTLHGPKFTGSWAVLGADRAGLTAAFTGDGDTYADLAALTAAVEAGAPVPE
AVLTVAPRSDQDGFLPGAVHGTVRDALELIQHWLADDRFATSRLVLVTSGAMAAEATDPV
TDLPHAATWGLFRSAQSEHPGRFVLVDLDEQDSSAAALPEVIGSGEPQAVVRAGTPRAVR
LARVHLTGEAPAFDAQGTVLITGGTGMIGTLVARHLVTQHGIRHLVLTSRRGAASPGAAE
LRDELAALGADVTLAACDAADRTALAELLAAVPQDRPLTAVVHAAGVVEDSVVTSLTPGH
LDTVLRPKVDAAWNLHELTKDLGLSAFILFSSAAAHFGNAGQGNYAAANAFLDALAHHRR
AEGLPAVSMAWSVWAERVQATDQSEEMRAERISAGAITAELGMVLFDHARRAGEPVLVPI
PLDIPAIRALPKDRIPILLHGLMPGDTRRSAGTEGPGEKGWADRLIAMPADKQRETVLAL
VRTQVASVLAYESADQVEDHRPFKDLGFDSLTAVKLRNQLAAVGGLTLPATLVFDHPTPV
ALAEFLRAELVPAEADPSARLLAELDRIAAGLPEIDPDAAGRDKITARLRSILWQWDESR
NGEGPENSEEDFDSATDDELFDALDNELGMS
>A0A1K2G2V4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. F-1|TrEMBL
MEAEFWETVEREDLAALAQTLDVQAGDTFGEVLPRLSSWRRQRRERAAVDGWRYHESWQR
LPRLAPTGPGGAWLLALPQEENEQTAAVRAVLTARGATLKTLVVDATHERTALARELAEI
GPVDGVLSLLLTGDPVLPTLLLVQALGDAGTDAPLWCLTSGAVAVGGSDTVRDARHAQVW
GLGRTVALEQPRRWGGLIDLPQTLDAQAAGHLADVLGRALTTRRQSDGTGPRAAGRTGRW
AEDQLAVRASGVHARRLAHAPARAATRRWQPRGTVLVTGGTGALGSHVARWLARGGAEHL
VLTSRRGPDAPGAAALRGELEALGARVTLAACDIADRAAVAALLAGHTFTAVVHAAGVAD
AGLVDATTPAAFTAALAAKAGGAAHLDELLGDRELDAFVLFSSISGVWGSGGQGAYAAGN
AFLDALARRRRARGLTATAVSWGPWADGGMVEDGDDEERLRRRGLRTMPPAAAITALQRA
LDRDETQLTVADVDWARFIVPFTLGRPSPLLGDLPEVRATLAEDAPEEGHGSGSLAEHLA
GLPPEDRTRTLVELVRTHAAAVLGHRTAGAVDADRPFRDLGFDSLTAVELRNRLNGATGL
ALPTTLVFDHPTAADLAAHLVAELTGDRAEPATEAAAGAVLDEPIAIIAMACRYPGDVRS
PEDLWELVATGRDAISRFPGNRGWDVEALYHPDPDHPGTTYTVHGGFLHDADEFDPTVFG
ISPREAVAMDPQQRLLLETTWEAFERAGIAPDAMRSTATGVFVGSGYQDYTGRPLKVPDG
VEGYLPSGNAASVISGRLSYAFGLQGPSVTVDTACSSSLTALHLAVQALRNGECAMALAG
GVMVMTGPSAFTMSSRQRALSADGRCKAFSSSADGTGFAEGVGLVLVERLSDARRNGHRV
LAVVRGSAVNQDGASNGLTAPSGRAQQQVIRQALANARLAPHEVDAVEAHGTGTRLGDPI
EAQALLATYGRERAGDRPLWLGSLKSNIGHAQAAAGVGGVIKMVMAMRHGVLPRTLHVDE
PTPDVDWSSGTVRLLTEQTAWPDQDRPRRAAVSSFGLSGTNVHTIIEQAPETPPAPATGG
QAPETHPAPATGDGHTPSTLPAPTADAHAPSAPQALPWALSAKSVRALRAQARRLLDHLD
RAEDLAPADIGHTLLTTRARLEQRAVVVGHDRQELRAGLAALADGRPADTVVQGTATARG
KVAFVFPGHGSQWPEMARELLDTAPAFAEQARACAEAFAPYLDWPLLDVLRAEPDAPSVA
EVEVAQPALFAVMVSLAALWRSYGLTPAAVVGHSQGEVAAAYVAGALTLDDAARIVALRS
RSLTKLIGKGAMLAVAMPAEQARARLERYGDRLAVAAVNGPAALTVTGEPDAVDALLAEL
EAEGVRVRKVRGATGAGHSAQVESLRPELLDLLAPVAPTAADIPFYSTVTGTLLDTTALD
AEYWYRNARHTVEFEATVRTLLADGHGTFVECSPHPLLADAVQEIAEEADAEAVTGGSLR
RGRGGLDRFLRSASELHVNGVSVDLTVPFAGRPVRRVELPTYAFQRQRYWLESADSVPAG
TDPVEAGFWHLVENADLPALTDEFGPDAAALVAPALPALSAWRRRGREKSTVDGWRYRVR
FRRLTDHPAPDLEGPWLAVLPAGRADEQWAPCVVGVLGAHGAKVRVVELPVDCDRAAAAH
RLTEELDGERPAGVLSLLGLAPGSHPAHPTLSASLATTVTLVQALGDAGIEAPLWCATRG
AVSTGAGDPLFDAGQAQLWGLGIVAALELPRRWGGLVDLPAKPDEHALRRLAGVLAQHDE
DQLAVRADGVYARRLVRARPADTEPTTPWRPRGTVLVTGGTGGVGRHLARWLAGAGARHL
VLTSRRGPDAPGARELRAELTALGAEVTIAACDIADRDALARLLAGIEARHPLTAVLHAA
GTARSSLLADAHLDEFAEAAAAKVTGARNLDELLDGRELDAFVLFASGAGVWGSGGQASY
ACANAFLDALALRRRARGLTATSVAWGGWAGGGMVDDTVQERGERRGLGVMAPELAISAL
HRAVGHDEAALTVAPIDWEKFLPAFTVARPSPLLSELPDVQRLLAAERTADAETGDGAGP
APELAALAPAEREEWLLEHIRAQSAVVLGHTSAEDVGPTAHFLELGFDSLTAIDLRRRLA
ATTGLRLPAGLAFDHPTPARLAKHLLTRLGDTGGGTPERPADLLVQLYRHASETGTAAEA
MGMLMDAARFRPSFDRPGELTEPPAPVRLSHGEGPVTLMCVSPYVVPAGAHQYARFAAPF
RGRLDVWALVNPGYEQGEPVPSDPDAVLLLHARTVRERAGGKPVVLLGYSSGGWIAHGVA
AHLEAMGEPPAAVVMVDSFSREIPFDHQVLNAMAQAQSRRLDFMKSGGEQLTAMGRYMRL
FDEWDAPRIAAPTLLVRASEAMPAGAPVDGDGRAAPPEHVDTTVEVPGDHYSMLEDHAAT
TAAAVDTWLADTVTGRTGPAVPPDATTTA
>B2IYP7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MVTEMSKSNERVEELSPLKRALLALETMQGKLNRLESKKTEPIAIVGMGCRFPGGVNNPQ
TFWQCLRDGVDAMQEIPGDRWDLETYYNVDADAAGKMYTRHGAFVDDVDKFDADFFSISP
REAAFIDPQQRLFLEVCWEALEQSGERPDQLAGSRTGVFVGVMYADYSRLQGTVIDAYSS
TGNSMSVVSGRVSYLLGLQGPSVTLDTACSSSLVTVHLACQSLRSGECNLALAGGVSLML
IPDNNITLCRTRALSPTGRCKTFDADADGFARGEGCGTIALKRLSDAIADGNPILAVIRG
SAVNQDGRSNGLTAPNGPAQQAVLREALANAGVKPHQVSYVEAHGTGTPLGDPIEVSSLA
AVLGEGRSPNHPLALGSVKTNIGHLESAAGVAGLIKVVLAMQHQQIPPHLHFQKLNPYIS
WGNLPISIPTELTPWDSGTERRIAGVSSFGFSGTNAHVILEEAPLLPTEPALVSVKDYLL
PLSAKNPAALLDMAQAYRAFLPGKTNLLDIAYTTSLRRPHHKHRIALVGQSIEQLTAALD
AFVEGESHPNLVPSNPHSDDLSGLVFVFSGQGAQWIGMGRQLLAQELVFRETIQECDRIL
KSLTHWSLLQELAAPEDISRLQDTEVAQPAILAIQVALTALWRSWGIEPAAVVGHSLGEI
TGAYVAGVFSLETALRIVVQRASLMQQATGKGKMAAIGMPWQELKPWLEEFPGLAIAAIN
SPASTVVAGDATALETLSQKLQAQEIFCRLLRVNYAFHCPQMQLYSEELVNLLAGLQPQV
AQLPLFSTVTGTSSEGRDWDAAYWGRNMRSPVQFSQAIENSVYEGYTCFVEVSPHPVLSQ
NIQECLQHTGKAGIVLASMHRERQERYFLLSELGRLYTLGYQPRWQALYPENRRCVLLPT
YPWQHQRYWLEGSNSLPARRTSRQPLLGESLPSLAHLPEMRIWQTQLDLRSLPYLNDHRV
QGVMVLPGSGYVEMVLAAATEIFGAGKHTLEVLHFQQGLFIPEAETQTVQICLQPGNTPD
TLNFDCYSRLSINPETKWRHHASGTVCRGDGEITPTIPVTVAEIQARCQEVISGTQHYQQ
MAEQGLLYGASFQGVEQIWRREGEALGRIHLPASLHAEIANYQIHPVILDACFQVIALAT
PLANPDAEAEGAYLPVRLDKLRLYQQPDATGLWAHLQLKPVVETDAFAAELVLFNDQGQR
ILDAECLRIQKLDSQSENNSSDWFYEISWERLLRQTDRETEGHSEQNQGYWLILTDRQGI
GENLSQQLQQQGGNCILAFAGETYQKQDSQHYQIQPNCLDDFKQLLQTVSSECLGIVHLW
SLDITPAELTTLASLTGDDNMGDRPLGDRNLGCISTLHLVQALAETGWQNTPRLWLVTRG
AQPVDSNLSIAQSPLWGLGRVIAQEHPDWRCSMVDLAPVPEPSEIPSLLQLLQADDVENQ
IALRGDVSYVARLKRYLPSYSELPNFHPQATYLIAGGLRGLGLQVATWMVERGARYLALM
ARSQLTPETLEVLQTLETAGAKIKVLQADISQAEEVAKAITQLDQDMPPLRGVIHSAAVL
DDGILLQLTPERLHKVMQPKIEGAWNLHTHTLNKPLDFFVLFSSAASLLGSAGQGNYAAA
NAFLDGLAHYRQSQNLPALSINWGAWAEIGLAAAQTNRGDRMASLGFSSILPQQGLDILG
HLLTDKTAQLGVIPINWAKVLRANPAVIKMPLFQLLTEVFSSSGEIDTDKSTNFLSRQAL
LATPLDERQLLLETYFHEQVARVLRMPASKLDRHQPLNSQGLDSLVAVELKNKLKNDLGI
DLPMIRFIQGPSIAQLSAQVLTQITQEMSSVSSVLVSPPHLRSNSARPVELATSNQEWED
GEL
>K9XMT2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Gloeocapsa sp. PCC 7428|TrEMBL
MNRESVDYRSLLQQALLEMRSLRAQLNAAQTVEPIAIIGMACRFPGGANTPEMYWQLLQN
GVDAISLIPPQRWAVDAYYDPNPDAPGKMYTRYGGFIADVDQFDPQFFGISPREAASMDP
QQRLLLEVSYTALENAGQSVQKLNGSRTGVFVGIGFDDYAKRSIFSGDPTRIDAYSSLGN
TRSIAVGRLSYIFGFQGPTMQLDTTCSSSLLAVHLACQSLQNRESNLALAGGVNLMLSPE
PTIGFCKLKALAADGRCKTFDAKADGYVRGEGCGIVVLKRLTDAIADQDRILAIIRGSAV
NHDGQSNGLTAPNGNAQEAVIRQAIAQSQIQPSQIQYIETHGTGTSLGDPIEVLALAKVL
AADRRQSPLYIGSVKTNIGHLEAAAGVASLIKVVLALQHQQIPPHLHFQQPNPHIPWEKI
AVPTQLTPWHTDANQPRCAGVSSFGMSGTNAHIILEEFPQAELATQQHSPQILTLSAKTP
TALRELAQSYQQYLHAHPDVSLADVCYTTHGRSHYDYRSAIVANSTAEAQKKLEAIETIR
TPLQRPKIAFLFPGQGSQYANMGQELYQTQPRFAQVLDTCCELLEPEIGIDLRTLLYSDA
SVALNETVYAQTAIFSIEYALSCLWTSWGVYPDVVIGHSIGEYVAATVAGVFSLEDALKL
VATRAKLMQALPHGQMLAIAASVDTVAAIITPYQDVAIAAVNAPNSTVISGDSQAISAIT
AILRDRNIASKRLEVSHAFHSPMMQPVVAEFERVAQTIEYALPKIDVISNVTGCVADNEI
ATPQYWCKHILQPVRFMSGMQTLAQHECNVCLELGAKPVLTALGRRCLPDADILWLSGLN
ESSEVFSNLAQLYVAGVEIDWQALKPQGQRLALPTYPFQRQRYWLETPQITISNAPADSH
PLLGQKVNLAKLETIHFQNQISLNNPAYLQHHRVFDIPIMPAAGYIEMALAAAAQVYQTH
NLVLTDVVIYKALKLTNELQKLQLILTPENQKYRFEIFSLAADQSWILHASGIAAATETP
EEVTLLELECPNSMAVTTFYQSCRDRGIDYGENFQRLTQLKQGKNAAIGQIETQEAAPNY
IFDPLLLDAGLQVIGAALSDTQTYLPIGLESLTFFGNVTNELSSSVQIRDELVDVQFTNS
EGLVAVIAGLKLKPAYPKAFQGTPTELYQVEWRLSQPLSESSSANLLSPAAICDRVIPAL
KQLLAQSELDSYRQVLPQLETLSLAYIVDALAAIGNDTNSVIPQYQRLLARLREIVLDAD
IVSSVNPQLLGQQLFAQYPMAGCELTLLQRCGSHLAQVLQGNQDALQLLFPDGDTSILTQ
LYQDSPGAKLMNTLVQQALNATVVNTNRVVRILEIGGGTGGTTAYLLPQLDVKTTEYTFT
DISPLFVSKAQAKFCDYDFVQYRVLDIERSPLTQGFDQQFDIIIAANVLHATQDLRKTLK
HTQELLAENGTLILLEGTRAFAWLDVVFGLTAGWWRFTDEDLRRSHPLLSSSQWQQLLHD
CGFESAIVSPAAVDDPLSQQNVIVARYTAKCTVTCLIFCDALGVGEALAKLLRAQGRRCI
LVYSAREYQRYGEDRFGVCLEREGDFVALIENLCEETNHRDAEEDTCVRGFPPLSKVSVG
AEVRGLEVVCLWGVEEVEGIETNLRSSCASALYLIRSLVATKLDASLYFVTQGAVDCGDV
SFSGLMHSPVWGIAKVAALEHSELEVKCIDLDDGVSVEVRAEALAAEVLSPDREDQIAWR
GDRRYVARLAKYQSIPQPYQLTISERGTLDNLQLQSYSRRVPELHEVEIRVFATGLNFRD
VLNALGLYPESALGCECVGEIVAVGAQVKDLVIGDAVVAIAPGSFSQYVTVDAAMVAPKP
ASLSWEAATTVPVTFLTAYYALHNVAKIQKGDRTLIHAAAGGVGQAAIQIAQQAGAEIIA
TASPTKWDTVRSLGVKHIYNSRSLDFAAEIMALTQGEGVDIILNSSPELVSASMSVLKAH
GRFVELGLVRDEYPQSAASYFSVDLVALCQQQPQLIQNLLRDLMLKFETRQLQALPQTVF
PIEKVVDAFRYMQQAKHTGKIVITNYQLPITNYQLPGTYLITGGLGGLGLLIAEWLVEQG
ARHLVLVSRRDDANHPQVQKLKKSGAVVVTASVDVTDEQQLSQLIADIKISMPPLRGVVH
AAGVLDDGALLQLDWERFEKVMYPKALGAWYLHALTQDQPLDFFVLFSSATALLGSPGQA
NHVAANVFLDTIAHYRRRLGLPALSINWGIWSEVGSASDRTQQMQQRGIDAIAPAEGIEI
FAQLLRSSNQVGVIPINWSRFLQQGMQSSFFNDFRVSEPQRPQLMQQLQTADTSDRRDLL
EKHIRTQIAQVLGFDPEEIDPYAGFFDLGMDSLTAIELKNRLQTTLQCTLPSTLIFDYPH
ITALVDYLMQQVLASDSQPEAYIEPDNTSEELSDDQIAELLAQELIEIARGKQS
>A0A6B9BIE1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium avium subsp. avium|TrEMBL
MSTVEGLRDPASSFAIVGYAARFPGAADADEFWRVLAEGRDAVSEVPKDRWDADEFFDPD
PDAPGKVVTRRAGFVDDVTGFDAPFFGMSAREARLLDPQHRLLLETAWRAVEHSGTAPTD
LANTNTGVFIGISTHDYLGMASDELTYDQIEAYTAIGTSSAAAAGRISYRLGLQGPAVAV
DTACSSSLVAIHQACQALRLGECDLALAGGANVLLTPATMITFSQAHMLAPDGRCKTFDA
AADGYVRGEGCGVLVVKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
EALQRAGIAPGDVDYLEAHGTGTSLGDPIEVQAAGAVLGAGREASRPLLIGSVKTNIGHL
EAAAGIAGVIKVILALEHGMLPQHLHFRDPSPHIPWDRLAVQVVKEATAWQRNGRPRVAG
VSSFGFAGTNAHVILEEAPDGTGRAAVPPAAVRPPGQRRFHVLPLSARTPAALVQIAGEY
RDWLSAHPDTALADLCLTAGAGRAHFEHRAALVVDSTGSAGELLAALADDRPAPGLLRGV
CEDAPKTAWLFTGQGSQYAGMARELFDTEPVFAETLTRCATVLADVLEKPLLDVIFDTDD
PASEATLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAGVLRLEDG
ARLIAERGRLFGSLPAGGRMVAAFAAAARVEGLTDEFPSLSVAAYNGANTVLSGPGQELE
QAVARLTAEKVRCDWLDTSHAFHSALLDPILDEFESYANQFDFGPPQRILICNRTGSALG
RSVKLDGAYWRRHARQPVEFAKSVHTLADLCCKVLLEIGPQPVLTAAALRAWPDPATAPR
AIASLRRNTADHRQITEALAEAYIVGHLPDFGAAVGPARKLDLPTYPFQHRQYWFSEQRV
PPGSQQTSTQTTAVRLLEDGRIAELAELLDGASADQHTLDVLTKLAAQHNQQRKSRSIAE
DRYEIRWEKSTVPGPEAEATWLVVGDDDDAVAPLVDALTARGHQHRILVLPASDADEERL
EIVLRAAAAEEAPLRIALVAALDSGTAPSMRSLLRMQHRVLAGTRRLFRAAAAAELRQPI
WLVTRGAQRVTDADTVFPDQSCLWGFGRAASLEYPQLWGGLADLAQGSAEEWSRLVRVAS
APRDPAVGEDQIALRGSDIYVPRLTRRSGQPAAAALTLRADATYLVTGGLGSIGLEIAGH
LAAQGARHLVLTGRRAPGEAAQRRIDALSQQHGCEVRVIAADVADAHHVARLLGAVRAEL
PPVAGIVHAAGEIGTTPLSDLEDAEIDRVFAGKVWGAWHLSEAAADLRLDFFVSTSSIAS
VWGGLGQTAYGAANAFLDGLAWRLREQGVNGISVNFGPWAAGMADENARARLAQRGIKTL
SPADALAGLADVMATAAAQGVVARIDWTRFLPLYQQAGQRSLLAELVREIPDFAPAPTPS
GKTGLVERLAGAPVQQRRKLMTEFLRNAVAEVTRVDAAEIREDAGFFDLGMDSLMAIELR
RHIEQGVGKQIPATLAMDYPRLSDVAEYLLGDVLDLRGQPDAKPAPPAGTPAPAGRTDEP
IAIVAMACRFPGAADPEAFWELLSGGVDAIREVPEDRFDIDEFYDPDPETPGKMYSRFGG
YLDQIDEFDPEFFGISPREAVWIDPQQRLVLETVWEGLERAGYSPAALRGSRSGIFVGVG
ANEYSHLLSAESVDKIEPHFITGNALNAISGRVAFALGLEGPAVAVDTACSSSLVAVHQA
CQALHSGDCDLALAGGVNVLLSPVSNIAASRARMLSPVGRCKTFDATADGYVRSEGCGIL
VLKRMSDAVRDGDRVCAVIPASAVNQDGASSGLTVPNGGAQQRLIATALSRAGLSGDDVD
YLEAHGTGTALGDPIEVQAAGAVYGATRDTDRPLLIGSVKTNIGHLEAASGVAGLIKVVL
SLQHEMLPQSLHFETPSPHIPWDSLPLRVVDKAVPWQTNGRPRRAGVSSFGFTGTNAHVL
IEEAPQPVTTQDATPAAESDARPVDVLPLSARSPEALLALAQRYGEWLHAHPDADIGDLC
FTVGAGRAHFEHRAALVVDSVRSAREALADLADNRTRPGVARGECTDPPTTAWLFTGQGS
QYPGMARELFDAEPVFAETVTRCADAVDGLLPRPLTEVIFATDKDTGGEAGKTLRNTAFA
QPALFAVEMGLARLWQSWGVEPDVVLGHSVGQYAAACVAGVFSLEDGARLMAERGRLFGG
LPDGGRMVAVFADAQYVEELANDCPRVSVAAYNGPNTVLSGPGADLEQIVARGASDGIRC
SWLETSHAFHSELLDPVLDEFESYAAHLDFAVPTLPLVCNRTGTVLTTETPLDARYWRRH
SRQPVQFAESVRTVAALGCTVLMEIGPQPVLTGAAVQVWPEHLAAPRAIVSLRKGVGDRR
QIAEGLAAAYVSGHRPEFAALHRRPRRKLELPTYPFQRRRFWPKASGIAGIDGQGAAASG
LLGSAKELASGDSVYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAAVGPPARVQNV
YFYEPIILPDKASREVQLSLHPLQEGGWSFRVDSRPYGVPDAEWSLNADGTVVAGIEDEP
AADPADHIDAVIERLDRSRPQLLFDSFAESELEWGTTWSTSLKSLWMGDGEAVGDVTVGD
ELAEHLGTEPMHPVLLDLCTGVVFPAFPALLAAEQGFNDLLLPLRYGQVSLREKMPRRFY
CRGKWRPSALDSETQVFDIDFIDRDGRHLGGIREFTVKRAPREALLRGLGGDATRLLYTL
GWHEVPPQPSNDGVANPSGTWLIAGFDELAAQLPGCIPFDRNTDPESFGQLLARAEDRGG
RVTGIVWRATQSGGQESSAESVARLETEIAGLLTAVHALQNADGSAVKLPGGLWIVTERG
VATESGEPVDPVQAALWGLGRTIVNEEPALRCRLVDSDGSEQAVRSLAGLLGAPLDEPEL
AVRQGKLLASRLLPWARSGHLAVPRGTDYVLAPTERGAIDNLRLIEQEAPPPAEGCVQVR
VEAGGLNFREVLNVLGLYPGDPGPLGGDFAGTVTQLGSGVTGLEVGTRVYGFMQGAFASR
FNVPVQLLAPIPDGVSAVDAATIPAAALTARLAFDWAQLKPGDRVLIHAASGGVGLAAIQ
LAQRHGATVFATASTYKRATLRKLGVEYVYDSRSTDFADQILADTDGAGVDVVLNSLTNE
GFIEATVRATAQHGRFVEIAKRDIWTREQMAAARPDIAYEIVALDWACVEQPEHIHALLT
EVSDGLASGEWRPLPAEIYPLAEAKTAFRRMQQARHIGKIVLQMPKPLQPRGDRSYLITG
GLGAIGLHLAAYLAQLGAGEIVLTSRRAPDAAARRAIDDITERYRCRVHTFAADVGDAAQ
VEQLLARIRAELPPLAGVAHLAGVLDDALLSQQSPERFRVALAPKAFGASYLDHATRTDD
LDFFIVSSSVSSLLGSPGQANYSTANAWLDGLVAARQARGLPATGVNLGPWAQGGMASSE
AARANIGAQGLIPLEPTAALAALAEVVANGTGQATVIKANWQRAAKLLGGARPPILDLVL
PSAVGEASGDSELLKQLQEIPVAQRAAFITEFLQREVQGFLRLAQPPAATSRFLDLGTDS
LMAVELRNRLHSQFGGAFTINATAVFDYPTIGGLAEYLAGQLPDAESEPGAAVAANPNPG
SETGTGEAEPEREAAPEPS
>A0A3N6DFQ7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI91-18|TrEMBL
MSAVQAQVWGLGRVAALELPERWGGLVDLPEVWDERAMARLVGVLAGSGEDQVAVRSSGV
FGRRLVRATGGGAGSWTPSGTVLVTGGTGALGGRVARWLAGAGAERLVLTSRRGADAPGA
AELTAELTELGVDVSVVACDAADRDALRTLLAAEADTLTAVVHTAGVLDDGVLDALTPER
FESVLRAKATSALNLHELTVELGIELSAFVLFSSMSGMTGAAGQANYAAANAYLDALAEQ
RRAAGLAATSLAWGPWAEGGMAADEAMDARMRREGLPPMAPDTAMAVLRRSVASSSDAAL
LVADVDWERFGPAFTVVRPSSLFAELAELAEVRPAGPVARTAGGAGSPVERFAGLGAVEL
ERELLGLVRTHVAAVLGHEGAETVGAERAFKELGFDSLTAVELRNRLGAATGVSLPATLI
FDYPTASAITAFLRDELLGSEVQMTAPVVTAVADDPIAIVAMSCRFPGGVRTPEDLWQLL
AAGGDAIGEFPVDRGWDLDRLYSPDPDRQGTFYAREGGFLYDAAEFDADFFGISPREALA
MDPQQRLLLETTWEAFERAGIAPSSVRGSQAGVFIGTNGQDYGATLQALPDGIEGFLGTG
NAASVVSGRLSYAFGLEGPAVTVDTACSASLVALHWAIQALRNGECDMALAGGVTVMSSP
GAYIDFSRQRGLAADGRIKAFSDDADGTGWGEGVGMLLVERLSDARRNGHPVLAVVRGSA
INQDGASNGLTAPNGPSQQRVIRAALASAGLSSSEVDAVEAHGTGTRLGDPIEAQALLAT
YGQERPADQPLLLGSIKSNIGHTQAAAGVAGVMKMVLAMQHGVLPQTLHVNEATPHVDWS
AGEVALLTERQAWPETGRPRRAGISSFGFSGTNAHTIIEQAPDDIREAASPVAPQQRPGV
VPWVLSGKNEAALRAQAERLLAAVTSDELLEPADVAYSLATSRSALERRAVVVAGERDEF
LAALRALAAGEQAAGVAHGTVSAGASAFLFTGQGSQRLGMGRELYDAFPVFADALDAICA
RMDGHLELPLKEVLFGSDAALLDETRFTQPALFAIEVALFRLLESWGVRPDFLSGHSIGE
IAAAHVAGVFSLDDACALVAARGRLMQALPAGGVMIAVQASEEEVLALLTDRVSIAAVNG
PEAVVVAGDEDVATAVAAAFPDRKSKRLTVSHAFHSPHMDGMLADFRKVAESLSYESPRI
PVVSNLTGALVTDEMASADFWVRHVREAVRFLDGIRVLEAAGVTTFVELGPDGVLSALAQ
DCTEQDALFVPALRKGRPEAEAVVTALARAHVHGVTVDWTAFYSGTAARRVDLPTYAFQR
KRYWLEEAPRPAAVEPGAGSGAVVDAPFWEAVDNADLDALAATLEIDADQPLSAVLPALS
AWRRRRADRSVVDGWRYGVTWKPLGEPDGSRPSGTWLVVTAATTAETAGSGLPEIADALR
AQGVDVREVALDAATDRAVVAERLDAALAGNRADGVLSLLALAEAPHPAHPAAPAGLLLT
GALVQALGDAGADAPLWCVTTGAVATGPSDRVRSAAQAQIWGFGRVVALEHPERWGGLVD
LPAAMDARALDRLLAVLGGDRAAATAGTGSGTDSGTAYEDQLAVRSAGLLARRIGHAAPA
AGAGGDAGADRAPWRARGTVLVTGGTGALGAHVARWLAAQGAEHLVLAGRRGPRAPGMEA
LVAELAALGARATAVACDVTDRRSVGELLAALRDDTTVPGLTAVFHTAGVGQFSPLAETG
PDDVAAVLAAKVAGAEHLDALLGDTELDAFVLFSSIAGVWGSGGQGAYAAANAHLDALAQ
RRRARGLTATAVAWGPWGEGGLVADEEAAGQLRRRGLPVMAPELSIAALQQALDADDTTV
TVADVDWALFAPAFTAARPRPLIADLPEVRRALAAEQPGAGGSGSAAGEDAAGEAARLAD
ELRGMGADEAERTLLGLVRTHVAAVLGHDGAATVEAGRAFKELGFDSLTAVELRTRLGSA
TGLRLPASLVFDHPTPAALAAHIRAELLGEDTAPEVPALAEIDRLEFLLTSVAEGDDAAE
RGRVTARLEALLAHWNRTERAAHPLEDEESAIESASAEDLFDIINNEFGKF
>Q2RSH5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1)|TrEMBL
MNHSMANRLPDIGQSVDRATVGLVFAGNGSQWPGMGAALLRDDAVFRESVSALDAKIRER
AGWSVIDALDADTSALTIARIGTAQPLLYALQIGLVDSLRARGLAFGAVCGHSVGEVAAA
TVVGALDPDQALDLILTRSAAQERTWGQGKMAALALSAIEAEALCAPYDGAVVVAALNSP
TSVTLSGDEACLIALGEQAKAAGALFRLLDLDYAFHNRVLDPVRDDLLKALAPLRPRPCA
PGYRFFSSVDGKARGGETLDARYWWDNVREPVRFDAAVTAMAAGGVTTFIEIGPHPILRS
YLREILQGRSRLGRGPHPIATLSRTRSGPEALQATLDHLRTPPSLQRKSA
>A0A2S9YP75|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Enhygromyxa salina|TrEMBL
MDKSELLRQSLLRINALKARVAELEAAPAEPIAIVGIGLRFPGGLGDPRQFWAGLCAGVD
VIQEIPEQRWPAGEAETRFAGMIDRIYEFEPGFFGLSEREARMMDPQQRLLLEIAWSALA
DAGLPLASVRGSETGVFIGASGFDWTLLAFAEQTIDAYSATGSSHSILANRLSYLWDLRG
PSFSIDAACASSLVAVHLGVAALRRRECDRVIAGGVQAHLVPHTTMSLARFGMMAADGRC
KAFDSRGDGFVRSEGCGVVVLARLSDVDLSRDRVYAVIHGSATNQDGRSNGLTAPNALAQ
ARVLKAALADARLAPEDVGLIETHGTGTALGDPIEFQAISSVYGEATRPCLLGAVKTNLG
HTEAAAGVAGLIKAALAIHHGRIPGNLHLERINPDVELEGTRFVLPRESTTWDGPRYAAV
SSFGFGGTNAHALLGPAPERENSKRPPSEIIFAPISANSREAFFERAAQLAQLAHDPAID
PHELAYTLAARSTHLPWRGHAIGRDRASLASALNQAHPTLASSTTPRVVFLFSGQGGQWI
DMGRALASWSAVFRDALSRCEQAITNVAGWSLSAALGSETELARVDRVQPAIFAMQVAAA
ALWRSFGVEPDVVLGTSMGEVAAAQVAGLLGLDDAARVITTRSQLVAERLDTPGAMATVA
LSEAEVRQRLAARPSDLEIAVVNSPINVVVAGSPAPLLELMAELEADGVFTRRIHVDYAS
HCSHVDKLSAGVEAALRGLAPGDGPRTPMLSTVTLAWLEDATAPSYWKANLREPVRLWPA
LSEVLRPAGDVVIELSPHPVLSVPLEDPLGQLDPPSSLSCGMARGGGPEAFLGALGRVWA
RGVEPRWTGPWLGGRVTSLPSYPWTRRSYGPGIRLADPRTGRAGVVASDASDAAPPVSDR
AELSVEALVVNTLAHELGATSELAMDVPLRELGLDSLMASHLRARLADHGYEIPLLEVLQ
AAGIRSLVAKLRDGATRDPAATPTRGPWFVTSRPRPQADVILYCVPYGGGSAGAFRPWND
AMPEWLEIRAVEAPGRGTRLGEAWPTSVDELVTELTRAIIDDLHTLDGQTFALYGHCSGS
LIAYEVARQLSAAGHVPRHLFVAALGPPARYKLDELVGAVERSGAALHDMSDDLLLGFLR
SVEFQGLEEFDRDVELRDMAMATMRADSRMMMTYRPVPAEPLGIPITAIGGARDPVINVF
ELWQWAPHTNVRFDWRWFPAGNHYFHVDHADELARVFAVLRADELPEPHPRTTTAIALTP
TDVVRSFYAAQGSDPTACEPFVADAVEWRILGMDALEPTDPERSARSWCTRASVSAVAMH
ELELALRGDDEIDAACSLTLKLATGGSCQHPHTARYRVRSGKIVAGEIHIGRP
>A0A5P9PZ95|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Amycolatopsis sp. YIM 10|TrEMBL
MLRTELIRPLPELLAAHAERLPAKVAFRDHRRAVTYAELHRRTGRLAGHLAGLRLQPGDR
ALIYLGNSVEVIESYLSIARASGVGVPFNPHSAAAELEHVVDDSGASVVITDPGHLEQVL
ALLAGRPYLRVVVTGDEPVPDHPAVVSYADLMATPPDLPARDDQELDDVAWMLYTSGTTG
KPKGVLSTQRSCLWSVAACYAPIIGLSEEDKVLWPLPLHHSLAHIFTVLGVTAVGATAHL
MDGFAAEDVLRALGEDDYTFLAGVPALYHYLLEASEGTEVRAHNLRACLTGGTVCPAALR
HSFERVFGVPLLDCYGSTEACGSFVVNGINGTRVDGSCGLPIPGVAVRLVDPDTGLDVAT
GDEGEVWVRGPNLMVGYHNQPEATAEAMSHGWYRTGDLARSDEAGYLTITGRIKELIIRN
GENIHPGEVEEVLRKVPGVADAAVVGRPHDVLGEVPIAFVVPGPGLDPELLFDTCREQLS
NFKVPEELYEIDEVPRTPSGKITRHVLLDRPARLRAASGGRHESLLRTDWVPLPSVRTSN
APLPTEWAVLGTDHFGLTAGLVAAGMSVRQHAGAAALHVAASLGEPVPEVAVLCCPSGGS
GTDAAHEAMRELSDLLWSWAHDDWLASCRLVVVTRGALATGAGEDVTDLVHASLWGLLRS
AQAEYPNRFVLVDVDEQSPPVLPFAVGSDEPQLAIRGGIAFRPRLMRVTANTDGQPMNLD
PKRTVVVTGATGPMGVALTRHLVAAHGARNLLLINPANDELETELGKLGARVTTATCDLG
DRDALGRVLDGLKRPVTAVLHCDGEVESPSAPPGDRRLAFRSIVDGATNLHELTKDGDLS
AFVLLGSVAGALGAAGRGDQAAAGAFLTALAQYRRARGLPAVCVALGTAAQAAELSTQEC
LAMFDAVTAMDLPHAVVMRVNEQTTSRTVPALLRGLVDAAPTTDSASLKERVAAMPPDER
ESFLVGLIRAEVATIPGIAGGARAGAGKTFRELGFTSVSAVELRNRLATSTGLDLTATVA
FDYPTPVALARHLRSVLLGEKPAPIVIDEPVSGPDEPIAIVGMACRYPGGVRSPEDLWRL
VTEGGEVVSDFPADRGWDLARLFGSESGATYCQQGGFLYDAPEFDAGFFGISPREALAMD
PQQRLVLETSWEAVERAGIDPLSLRGSKTGMFAGVMYHDYGWGLADPPEGSEAYWGIGNA
GSVVSGRVSYALGLEGPAVTVDTACSSSLVAMHWAGQSLREGECDLALAGGVAVMSTPQT
FVEFSLQGGLAPDGRCKSFADAADGTGWSEGVGFVVLERLSDAKRNGHTVLAVLRGSAVN
QDGASNGLTAPNGPSQQRVILRALANAGLKPSDVDAMEAHGTGTTLGDPIEAQALLATYG
QDREQPLLLGSVKSNLGHTQAAAGVAGVIKMVQALRHGVLPKTLHVDQPSSYVDWSAGAV
ELVTEQRELPSLDRPARAGVSSFGISGTNAHVIIEQAPPQPRVVEPAEVTPSVVPWLVSA
RSAAALDAQADRLRALDGDPLDIGFSTVISRSVFEHRAVLVDGTEIARGEAGDRSVAILF
SGQGSQRIGMGRELYQRFPVFASALDEVLEHLDVRDVMWGPDEDALNQTGATQPALFAIE
VALYRLIESWGIRADYLAGHSIGEIAAAHVAGVFTLDDACKLVEARAKLMQALPADGAMV
AIEATEDEVAPLLTDEVSIAAINGPRSLVISGNAQVTAEIVAGFAERGRKSRRLPVSHAF
HSPLMNSMLDDFRAVVSGLSFTAPRVPVVSNLTGGVATGAELCSPDYWVRHVRGTVRFAD
GVRALAEAGADVFLELGPDGVLSGMAADSAPDATLVPILRKDRPEELGALTALAKLHVIG
VPVSWRAVFAGTGARRVDLPTYAFQRQRFWPELAAPATATGSDPVDAAFWSLVDDGDLAT
VASALEVDPKTAATMVPALATWRNRRRAQSVVDSWRYRESWVRLPEPSAPAGRSWLAVLD
REDEWTTAVLAALGPDVVRVEVSDRKAMATKFEDLAGQEFAGVVSLAGLSEAPSHGAVPA
GLLYSVEVVQALGDAGIEAPVWLVTRGAVAVGKPGEVTRPEQGALWGLGRSAALELPRRW
GGLVDLPERFDDQAGKRFAAVLIGHEDQVAVRSGGVFGRRLVHAPATGARPENWRLRGTV
LITGGTGGLGGQVARWAVASGAEHVVLTSRRGPDAPGAAELKAELEAEGTRVTIVACDAA
DRDALREVLAGIDVNSVVHAAGVGVGDAPIGSVTAEQLDGLLRSKLTAAWNLHELTGDLD
NFVLFSSGAGSWGSGGQPGYAAGNAYLDALATHRRGEGLPATSIAWGSWADAGLGADNPE
LSEHMRRVGVLPMEPRLAIAALQQALEDGETLLTVTNTDWKRFAPSFTATRPSPLLADLP
EAVAAVATEPETGAEPELRQRLAELSEADRARVLLDLVRAEAAAVLGHDRPQAIPADKVF
REQGFDSVTAVEVRERLRVKSGLSLPAALVFDYPTPRAVAAYLGENLVIEQPRGSAVSEL
DRFEAALWAENTDTQVIGERLEAILQRLRKPAAARSSEEDINSVPVDRLLDIIDGELSDL
S
>A0A5P9PYG4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Amycolatopsis sp. YIM 10|TrEMBL
MTTEDKLRDYLKRATAELRQARERVAELSGRATEPIAVVAMGCRYPGDVRSPAELWELVA
SGTDAISGFPADRGWDVEHLYDPDPERVGTSYTRQGGFLEDADHFDADFFGISPREALAI
DPQQRLLLETAWETLEHAGIDPLSLRGSQTGVFAGVMYDDYASRLHRAPAGFEGYLGNGS
APSIASGRVSYTFGFEGPAVTIDTACSSSLVAIHLAAQSLRQSECTLALAGGVTVMATPS
TFVEFSRQRGLSPDGRCKSFSASADGTGFAEGAGLILLERLSDAERNGHPVLAVIRGSAV
NQDGASSQLSAPNGPSQERVIRQALAVAGLEPSEVDAVEAHSTGTTLGDPIEAQALLATY
GQHRRDRPLWLGSIKSNIGHTQAAAGVAGVIKMVLALRHETLPRTLHADQPSPHIDWAAG
AVSLLSEPVPWPENGTPRRAGISSFGISGTNAHVILEQAPKAEPDPEPPADGRPVPWLLS
ARSERALHVQAQRLRRHVVSSTSDPATIGYSLATTRSTFAHRAVVVADNREDFLHGLDRL
SRGESATGLITTPHGAQNPVAGAREPVFVFPGQSSQWARMAVPLLGTSDVFREQIQLCTD
ALAPHVDWSLRDVLEGAPGSPPLERVDVVQPALFAVMVSLARLWQSIGARASAVIGHSQG
EIAAAHIAGALTLEDAALIVARRSQAVSALSGRGGMASVPLPASRIREHPALLDGRLGIA
AINGPESTVVSGAKQAIDELLAGYEADGVRARRIAVDYASHSPHVDTLRESLLDMLAEVK
PLPAEIPFYSTVTGEPIDTTELDAAYWYRNLRETVQLDKAVRALRRDGHRSFVETSPHPV
LTIGIQQTLDETREDGVSTISGTLRRDNGDWKQFLAAAAQAHVNGVDLDWTAVFPSGTAK
RVDLPTYPFQRKRYWLDAPAGATDPTAAGLDAADHPLLSGALELADGDSTVFTGRLSPHA
QPWLADHTVLGTALLPGSAFVDMALFVAERTGCAQIDELLLQAPLVLPEQGTLRVQVSAG
PVEDERRRLTVHSRPEDAEPDDPWTLHVTGSLSVEAPEVAGDLTGSWPPAGAVPVEMDEF
YERLQDEGYGYGPTFRGLRGVWKLGEEIYAHVVLPEEQHADGERSALHPALLDAALHPLA
RESLGGDGISLPFSWNGVSLRTTGATALRVRLTPLGTDSYRVTLADSVGTPVASIDTLTA
RRINPARLGSGGHRSMLFHVEWSALRETELAAEATPEVVTADDVPAALHLVQQAIADDKR
LVFVTSGAVSTEPGEDVTDLTGAAVWGLVRSAQNEHPDRFTLVDTDSPQSIPAVGEPQLA
VRNGKALVPRLTRTAADLTHTPLDPAGTVLITGGTGVLGGHLARHLVLNHGVRHLLLTSR
RGLDAPGATGLAADLADLGAEVRITACDAADRAALEALLNTVTRPLTAVVHAAGVLDDAT
ITALTPDQLENVWRPKVDAARNLHELTGELSAFVLFSSIASIIGTPGQANYAASNAYLDA
LAEHRRAQGKPAISLAWGYWAETTGMTGHLDHADHTRMARAGIVPLATEQGFALFDAALT
TGRAVVVPAKMDTAALRNQATAGTLPRLFQNLVKAPAKRAGGGMADLAQRLADLAESEQQ
ALLIDVVRGHVATVLGHTDPDTIPTEKAFKELGFDSLTAVELRNRLTAATGLRLPATLVF
DHPTLAGLAGYMRAELAPRTEEPDPASAVLERLQGLEEDLIGLSDLRVTDRLRELLAVAG
GADSGLGSASADELFDFIDGKLGRKVETA
>A0A100J4B2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MTNGEALRARLTEPAPTARHGVLLDLLKEEIARTTDSGGHVDVQAPWRRLGVYRDVAQRL
RDRVAEATGLRIPATALFDYPTPLAFAEYLTGRLTGAARPRQAGATDAYDTRDTDPVVIV
GLGCRLPGGADSPEALWRLVDEGRDAIAGLPEDRGWDLAGLYDPDPQQHGTAYTRYGGFL
TGVGDFDPGFFGIGPREATALDPQQRLMLEISWEAMERAGIDPHTLRGTNTGVFTGVSLQ
DYGPAWHEAPEEAQGQLLTGNALGVVSGRIAYTYGFEGPALTIDTQCSSSLVALHVAAQS
LRTGECDLALAGGVTVMSTPGMLLEFSRKRGLAPDGRCKAFSADADGTGWAEGAGVVILQ
RLSDARRDGHRVLAVLRATGTNQDGASNGLTAPNGPSQQRLIQRTLAAAGLTPADVDAVE
AHGTGTALGDPIEAGALIGAYGQDRPEDRPLRLGSLKSNIGHTQAAAGAAGVIKMVMALQ
HERLPRTLHAETPSPHVDWSSGSVELLHQPVSWPRTDERPRRAAVSAFGVSGTNAHVVIE
EPPADTPAAGHPAALVVSARTEDALKEQSARLGTHLAGHPGLRLTEAAATLAGRARFEHR
AIVVTEDRDNAVRALLTGTGPHVTRGSVSPRVADGRLAVLFTGQGGQRHGMGRELYTAHP
VFARALDEVCARMDAHLEHPLRDVMFAPEGAELAGLLGETAYTQPALFAYETALLRLVES
WGIVPDVLLGHSVGELTAAYAAGVWSLDDACALVAARGRLMQSCRTGGAMAAIQATEDEV
LAGLAAYGERAVVATVNGPAATVIAGDADAVDEIAGLWREHGRKTKRLTVSHAFHSPHMD
GMLAEFRDVAARVGYRSARLPVVSNLTGRVATDEQLSSPDYWVRHVREAVRFSDGVRTLH
EEGVTAHLELGPDAVLSAMGPGCLPDDAVFVAAARAGRPETVTLLTALAELHVQGLAVDW
SALHPDAHHVDLPTYAFQRRRYWLEPATRTAAPAIPATSPADLRYRVTWRPVVPEPTAAP
PTLSGTWLLLTPPTGAGEELVARVAWTVDRRGGRAAIVPVDAQHAERGRAAELLDKQLAD
AGGEFGGVLSLLALDPTDGLTLTCALVQALADLDVAAPLWCATRSAVTVTEGFGSEGSGA
PQRDVVGSPDQAMVWGLGRTLALERPRGWGGLIDLPAVLDDEATLWLGTALTAPEGEDQL
AVRTGGLYARRLTRAAEASDVAGTDWRPRGTVLVTGGTGALGARVARRLAETGAQRLVLT
SRRGQEAPGAAELAAELTALGVDVRVEACDMSDRDQVAHLLQAIPDGELTAVVHAAGVVG
RFAPLTDLDPGEFAAGVAAKATGAALLDELLGDTPLDAFVVFSSISATWGSTGQTAYAAG
NAYLDALAAHRRGRGLAATSVAWGPWAETGMGAEEGMSRFLARRGLPPLDPGTAVDELWR
AVGASETSLTVADVDWDRFLPPFTATRETRFFDEIAVHRQESPSGSGETEQVTTTADPLL
TVRTEAAAVLGYASPDDISPTRRFLDLGFDSLTSVQLRRRLITATGLPLATPVVFDYPTP
EELARHIGELAASEKPVSTVAESEGLGVRGLYRRACEIGKFTEGIRILQAAAKLRPVCHD
AAGFGRPYDVVRLASGPARPALVCLPSMVAPSGPHNFARLALHLHGRHDVYALPLPGFGD
DDPLPASSELVVEMHADAVLRELPDTPVALAGYSSGGWLAHAVASRLEARGHAVRAVVLL
DTWFPQDDIAEDQVQEQLQGIAVNAHAFALMTEAQVTAQGAYLELFEGWQPQAVSAPVLL
ARAAERMPQRGEAEGDAPRGWSAEWDFAHDTVDAPGNHQTMMNEHAAGTAAAVSEWLRGL
>A0A100J3Y8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MGHEADGKDSASVPVAWVLSARTGAGLAARAARLSSQVRSDPGTPETEIGARLVAGAASS
GERAVVVDDTREGLLAGLDALASGREAPNLLTGTGEAGRRVVFVFPGQGTEWPGMAVDLL
RSEPVFAERVRACERALAPYVDWSLEEVLTGCDSAPSLDRVDVVQPVLFATMVSLAALWR
SFGIEPAAVVGHSQGEIAAAHVAGALSLEDAARLVALRSRALDAIRGDGAMVTVMGSGGQ
VREMLSGQEGRLWVAAVNGPGALTVSGGLEALTGFESALSAARILRWRLPRVDFAAHSGQ
VEAIRDEVLRLSKETRPCDTAVGFYSSVTAGRIDPAELGGDYWYRNLRETVRFHETVTAL
LADGYDAFVECGPQPVLNLGLQETADQAGIPVSLLASLRRGEGGMRRFVTALADAHVHGV
PVDWRRLYGKAGQGASC
>A0A1Q2ZQX4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MSGGEVPWVVSARSSGALEEQVRRVGELEASAVEVGWSLVATRSVFEHRAVVVGGDVVSG
VAGDIGPGPVLVFPGQGSQWVGMGAQLLDESPVFAARIAECEQALAPHVGWSLAEVLRGG
GELDRVDVVQPVLWAVMVSLAAVWEGYGVRPAAVIGHSQGEIAAACIAGVLSLQDAARIV
AVRSDALRQLQGRGDMASLGVGTDQAAELIGDRPGVSVAVVNSASSTVISGPPGEVAAVV
SEAEARGLRARLIDVGYASHHAQIDELREELEERLSGVHPGAVSDVAFYSTVTASRIDTA
TLDTGYWVTNLREQVRFAETIEALQADGYRLFIEASPHPVLVLPMEETIETGTVVPTLRR
DHGGTEQLTLAAAQAFVAGADINWHHWFPTPPHPIDLPTYPFQHHHYWLKPPSAPPFTTT
SADPIEAQVWQAIEDLDIEALTGSLEIEGRPETVGVLEPALPVLSAWRRRHRERTTLNSW
RYRITWKRLPDTTAPHVTGTWLLLAPTTHPDHLAVRATAQALTAHGAEVRQHLIDTRSSE
PPELDTSGLTGIVNLLALDEDPHPDHPAVPAGLAATTALIQVLAATETPLHTITQGAVGD
TLTNPIQAQVWGFGRVAALEYPRLWAGLVDLPARVDHQTLPRLAAALLRQDEDQIALRPT
GTYARRLVHAPADRGTAPSWRPEGTVLITGGTGGIGAVLARWLAHQGAPHLHLISRRGPD
APGAHQLTTELTDLGTHVTVTACDVSDRDQLRDLIDTHPPTAIIHAAGVPNYIGIAELSG
AALDEVLRPKALAALHLHELTRELNLSAFVMFSSGAAVWGSGQQAAYGAANHFLDALAEH
RHALGLPATSVAWGPWADAGMAADQATLTFFSRFGLQPLAAELCVKALHQAISSGEPTLT
VADFDWARFTPTFTAQRPSPLLADLPENRRESAPAEQESGAAAGSSQELQRELASANPVQ
QRQLLLQHVREQAAATLGHADVDSVPASKPFQELGFDSLTAVELRNRLNKSTGLTLPTTV
VFDHPTPDALAGVLRAELSGEAAAVDVARAAVAVADDEPIAIIGMACRYPGGVRSAEDLW
ELVADGRDAMGGFPDDRGWDLEKLYDPDPESRGTSYVREGGFLYDAGDFDAEFFGISPRE
AVAMDPQQRLLLETAWEAVERAGLDRGTLKGSDTGVFAGLTIFDYLALVGEQSTEVEGYI
GTGNLGCVASGRVSYVLGLEGPAMTLDTGCSSSLVAIHQAAHALRQGECSLALAGGATVM
ATPGAFIEFSLQRGLARDGRCKPFAAAADGTGWAEGVGLVVLERLSEARRNGHRVLALIR
GSAINQDGTSNGLTAPNGQAQQRVIRQALANSRLSGEDVDAVEAHGTGTMLGDPIEANAL
LATYGQDRPGDRPLWLGSVKSNIGHAQASAGVAGVIKTVMAMRNELLPRSLHIDEPTPHV
RWDGSGVQLLSEAVPWTRGERPRRAGVSAFGISGTNAHVILEEAPPSEEATSAKEPELVP
WVVSARSEAALGEQVRQLGELEASATEVGWSLVTTRSVFEHRSVIVGEDTVSGVAGDIGP
GPVLVFPGQGSQWVGMGAQLLDESPVFAERIAECERALAPHVDWSLTEVLRSASELTRVD
VVQPVLWAVMVSLAAVWEDHGVRPAAVVGHSQGEIAAACVAGALSLQDAARIVAVRSDAL
RQLQGRGDMASLGTSAAQATELIGDRPGVSIAAVNSASSTVISGTPAEVAAVIAEAEARG
LRARLIDVGYASHHAQIDELREELTQRLSDVHPGTPSDIAFYSTVTASRIDTTTLDTDYW
VTNLREQVRFAETIKILHQDGYRLFIEASPHPVLVLPMEESIDTGTIVPTLRRDHGTTHQ
LTLAAAQAFTAGADINWRRWFPAVPPPRVVDLPTYAFQHQRYWLDGPRGVAGDPAGFGLV
PAGHPLLGAVVELADGDSRLLTGRLAARDQAWLAEHQVMDRVLLPGSAFVELALQAAVRS
GCDEVSELTLHTPLVFGDEGAVDLQVVVGVAEEDGRRSVAVHARPVGEPAWTRHAAGAVA
RAGTDAVEPEFGGVWPPPGAVPVGGDDPYGELSSYGYEFGDASRGLVGVWRVGDDLFAEV
ALGEVQGGEAGRYQVHPVLFDSVLHAVVLDAVGSSAASGDVLLPFDWSGLRVFVPGAERL
RVRVVRVAADRLALSAVDELGVPVLALESLTVRPVAARQIVGARAERDALFRSVWREAEI
SGGAVRAGVVAAGGSSVLAGVPVCGSLDGLRDDVPDVVVVECAASGVGASGAVVELLGVL
KEWVDDPVFAASRLVVVTRGAVVARPGEGGGEPAGAALWGLVRSAQAENPGRLTLVDVDE
DADSLAALPGVLACEEPELAVRAGRVLVPRFVRDDASGRLVAPVGSSWRLEWSGGQWGVV
DAPECGREVAAGEVRVAVRAAGVAGAGVVTEVGAGVGGIAVGDRVMGGFGVVGPVAVVGA
GAVAPVPEGWSWARAAGAVEVWDVRQAPVAPPSAVFVLPVPFDPEGTVLITGGTGALGAL
TARHLVSRYGARHLLLCSRRGADAPGALELGAELSALGARVSFAACDPGYREAAEALVAS
VPAEHPLTAVFHCAGTVSDAVVQNLTAEQVEEVMRVKARAAWHLHELTRDMDLSAFVLYS
SVAGLLGGPGQGSYSAANAFLDALAVHRYAGGAHAVSLAWGYWDLPDGMSGRLTDADRAR
HARAGVVGLGAEEGLALLDAAWASGLPLLAPVRLDLGRLRREAGSRLVPALLRDLVRPTK
AGGGVSAGAAALRKALGTASEAERERMLLDLVCTQVAAVLGHDAAASVNASQGLRDLGFD
SLTAVELRNRLSAATGLKLPATFVFDHPDPAALAARLGAELAPRAVDPLAGVLAEFERLE
GSLLAVSSRDGGARLELAGRLRATLARLDVPSGAADGSAVAARIQDASAEEILAFVDRDL
GRDSGNGRTVEGQR
>A0A084GE65|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudallescheria apiosperma|TrEMBL
MISRPPETANGTHDDDALPPIAVVGMACRFPGGASTPSKFWEMIANKRSGRSEIPKSRMN
VDAFYHPDPDRGGSFNIRAAHFLDQDISEFDAAFFSISPAEAVGMDPQQRLLMECAYEAV
ENAGVPMEKLAGSNTSCYVGCFSKDYHESLSRDLEVSPAYVCTGNGAAILSNRISYFFDL
KGPSLTVDTACSSGLVAFHLACQSLRAGESKASIVGGANLIFNPDPMVAMSNVRFFGPDG
RCFTFDHRANGYSRGEGIAALYLKPLEDAIRDNDTIRAVIRGTTSNQDGRTPGIMLPSGE
AQHALLTSAYQSAGCDPAVVGYFEAHGTGTVVGDPIEAGAIGSALGKYRPEGQENALYVG
SFKTNIGHLEGCSGLAGVIKTVLTLENGLIPPNINFERGNDKIDFEGCRIRVPTELSPWP
VAGVRRAGINSFGFGGTNVHAILDDAYNYLQLRGLRGSHRTVVNPSLHGKHEALTAVTNG
NDNVNGNGVNGNGVKGNGVNGHSHTNGHSDGNGTHFERDAVQTNGHEKATESGSQHRIFV
WSAHEATSAKQIVSTYASYLKQEKIVEGSKDEASFLNDLSYTLGERRSSLPFKVSVVADS
LDDLVTKLESLNQSPTRSDINQAPSVAFVFTGQGAQWCGMGQQLFESYPVFQKSIQLAND
TLASLGCTWSLIDEVIVPTDKEASRVNDPEVSQPACTAVQLALVDLLNDWGILPQMVIGH
SSGEIAAAYAASKLTFASALKVAYFRGIVSSQVKQEGAMMACGLSAQDAQERISRLDPAS
GKLVVACMNSPSNVTLSGDLTAIQAMENMIKEEDESIFARKLKVKTAYHSHHMKDVASHY
LELLGELEIPTREASTPQKCEMISTVTSASTADVDLGAQYWVDNLLSPVRFSEGLESLLL
SGASSRTRKSLETGGGRSPVSILLEIGPHSALAGPVKQIVSSALEKASHGTNRSISYFSA
LIRGRNACETSLDAAASLWTCGVSVRLRRANEPVQSSSTPQVLVDLPSYSWNHKKFWMES
RLSTDYRFRSAPRIDLLGAPVSDWNPTEPRWRNFIRIQEQPWVKDHQVQDTVIYPAAGYI
AMVLEAARQITSSQDKERVTGFTIADMVISRALVVPQTDAGVEVMFEVRPLRSSSKTSSD
VWKEFRVFSFSTPGETQEHCRGVFTVTLAQQQPDVVDDGREGKEATNWYDENFDSTKKQC
TTPVATSQIYETLTNIGLLYGPTFRNLTNISYGTGKATATITIPDTKKVMPFEYEHEHLL
HPATLDAFLQSFFPALTRSNIKEAYMPTFIQKIEVSNAVAANKPGFELEAVSEAAFAGYR
QASGTIYVRDSLSKTPVVTVQGLRCTAVTSTDPGADGVSSGEEKKLCFDVQWALDLDLNG
KDEVEALLGDTGVADTSPDYIGTLEMVASYFYQKALKEVGESQVVQPHHQKLYRYMQHHR
EQLSSGKVAHQTSQWLQFDTPEVQEKMENLISTVESADHEAMLLCRVGKSLSCILKGDVD
PLALMLEGDLLYKYYENALGLATTYAQLGKYITLLSHKHPNLRFLEIGAGTGGATWPILQ
ALGGNKGAYPRFEDYTYTDISSGFFEKAQEKFRDWGDLIRYRKLNIEQDAVSQGFAENEK
FDVVVAFNVLHATANISNTISNVRKLLKEGGKLLLLEMTQVLNRGFLPFGTLPGWWMSEE
DFRPWGPTMDEATWDSVLGKCGFGGLSLSIPDHRDSRLQCGRLMVAEAIHDTPIPKSNGD
LAGSSPSIIIITTEARADGEEEFVAGLQQRLLEKGHSSSAKSVSQLSEKELTSTICVFEA
EMWQPLVKDISPADFEQLKLVLDKAAGLLWLTVGGSQEANNPDAALIHGLARTLRGEHPG
LPFITLDFSADSPLSATECFDKIYLVLEKVLSARPAAEEDTEYSEKGGHLYIKRCLEATG
LDARLSELGGKATSGLETKMEPFYQPDRPLTLDIAVPGLLDTLRFIDDPTGPMQLPPDYV
TIDVRAVGLNFRDIMVSMGQLVDGFLGCECSGIVAEIGSEVTHLKVGDRVCAWTMGGYSN
SVKNPAKLVQRIPDSMEFETAAAIPVVYCTAYYALVDQARIRKGESILIHAAAGGVGQAA
IMMAQFYGAEVFVTVGTKQKKEHIMATYGIPESHIFSSRNLSFAEGIKRQTGGKGVDVIL
NCLSGEALKASWSIIAPFGRFIEIGKKDIEENTHIGMAPFIRNVTFASVDLTVMFKQRRD
LALHLITSVMALLRDESIGVVTPITTFPFSKMEEAFRYMQMGKHMGKVVLTPQRDDIVPV
VPRKKTGIKFEPDASYLLAGGFGGLGRCLARHLVRHGAKNLIFVSRSGTSRSESQSLVDE
LEAAGTNVRVLACDVTDDNKLQSAFGAALAELPPIRGVIQASMVLEDRVFANMPYETFAK
VIGPKVHGTWNLHNATLNQPLDFFVLLASAAGTIGDLSQGNYAAANAFQDSFAHYRTSRG
LPATVVDLGMIRSVGYVAETEGATQNNLSRWGFVLIDEEEFLAMMSIAMEGSNINDGEKR
CQFVTGLGTQAYFDRTQHEIPHWFNEPVFSHLRMMRARTVGAKTDVEVSLVQQLEEATSI
DAAAAIVVDALLKKLSKALMIPLEDIHAASPTSAYGVDSLVAVEVRNWLLREFKADIPVF
DILQAPSLQLVGYKVVEKSGLLSEKFTRAED
>A0A0N0N7Y3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OV320|TrEMBL
MSLHEESLPEDERRPLSGAQEGLWYAQRLAPDSAAYNTAEAVEIHGGLDIALFEAALRRT
VGEAGTFALRFLDTDDGPRCRPAPDADDWPLHRVDVSDAADPEAAAWKLIRADLATPVDT
DKGPLFAHTLLTLAADRHIWLLRAHHLLLDGYSYKLLGRRLADVHNALAEGRDPGPGGFA
PVGRLRTEEAAYLASERRDRDRDHWTRRLADLPEPARLTRRTAPPRAPFLRHTVELGPLD
AEALSAAAAGLGITRADLIATALAVYLHRMTGTDDLVLGMATMSRLGSAALRTPGTASDV
LPLRVTARPGTAVAEFARTVADELAALRRHQQYRGEFIRRDLGLLGSGRRLHGPVLNIVP
FTEELDFAGSTATWHHLSGGAVDDLQVNVRPGTRPGSLWLAFDANPHLYEADELALHGER
FLALLRRLAQAAPTTALADLDLLLPGEHPRGRPVREFPVTGTLTELFERQVHARPGRIAV
THEGAHLTYGQLNEEANRLARLLVERGAGPGRTVALALHRGPLLLPALLAVLKTGAAYLP
LDPAHPAERLCLVMADAAPVLLVTEGGLAADLGGDVTTVVLDEPAVTADLAARPAADLTD
ADRGGPTGPTHIAYVIHTSGSTGRPKGVPVPHANVVRLFAASAEHFDFGADDVWTLFHSY
AFDFSVWEIWGALLHGGRLVVVPYAVSRSPRDFLRLLHDEGVTVLNQTPSAFEQLVDADE
EPTAGALRYVVFGGETLRPERLRPWTARHGLDRPALVNMYGITETTVHVTHLRLTPDDLT
DPRRGNVVGTPLADLRVYLLDPQGRPVPPGAVGELYVAGAGVTPGYLHRPELTADRFLDD
PHGPPGSRMYRSGDLARLRADGALDHLGRADRQVQLRGFRVEPGEIEAVLAEHPGIARAA
VVVRRADHGAEQLVAYLVTTGERPPAAAEVRAHAADHLPEHMVPAACVLMDTLPLTANGK
LDTDALPEPDLVGAAAGARPASTEQALVCALFEDVLKLPRDTVGIDADFFDLGGDSLLAT
RLLARLRHGSGTDVPITALFEGPSPAALARLLDGRPGTAPGRPALGELPRPERVPLSYAQ
ERMRFLNRLDGSTATYNIPLVVPLGAAADTEALRAALGDLADRHEILRTVLADHDGTPYQ
RILPAGGPRPPLPAVDCPADEIGAHLAAASRLRFDLTGEPPLRAWLFGTGEDRTLLLVLH
HSAADGWSLRPLADDLTTAYAARRAGTAPAWDAPSAQYADYALWQRALLAPGPDGTGHAE
RLTAHWRQALAAAPQECTLPGDRPRPTAPRDGAHVTEHVPAALHRDLTGLAEREGSSLFM
LLHAAVSALLTRCGAGEDIVLGVPVAGRSEPGLDDLIGLVTNTLVLRADTSGNPAFRELL
ARVRPGDLAALGHQELPFDRLVDELNPPRRPGRHPLFQVMLALQNNEPAVLRLDGHPALL
RPTATGTAKFDLFVDVLERHTADGTPDGLDLHIEYATDLYDPSTAEEFARSLGRLLATVS
ADPDVRLGGLPAPAPRTPAEAPGPDTAGLTEAARSVPGIRDAVALPAADGGPPRLFVVPG
RAEATEAVERLLERTGTTTVGVTAVSTLPRDADGALDPAALTALPAVDRAAAGAWRQRLA
RVTGVGAAEAGVEDIPSELARRHAAAPRRAAPASDGGTRGAAGTRPALSEGPEQAEPTVA
TWAQALVRAADHARGDIVHVHPDGSETRRDYASLVPEASRVLAGLRRAGLRPGDQVILQC
DAGEDFLAVLWGCILGGFVAVPLTVPASYDTPSAALTKLEGIWRMLGRPWIVCSPALEAG
LRDRTGHDGGSGLRLTTADALRDAPEDRDWYAAQPDDLILMLMTSGSTGLPKAVRLTHRN
VLARSAATAAMNGLGADDVTLNWIPLDHVTGVVMFHLRDLYLGCRQIHAPTSWILQDPPR
WMDLAHRHRVSVTWAPNFAFGLLAGQAPRFADRDWDLTPMRLVMNAGEVVVAAAARGFLH
ALRPFGLPQDVMHPGWGMSETCSVVTDAVLPAEPPGTDETFVSCGLPYPGFAMRVVGEDT
TVLTEGEAGRLQVRGTSVTGGYHDNPAANAEAFTDDGWFDTGDLAFLRDGELFITGRAKD
VIIVNGVNHYSHEIETCVEELPAVVRSFTAACAVRSDASAATDELALFFHLAPVPDRAAA
LREIAGKVTREIGVSPAFLVPVGPGDIPKTEIGKIQRTKLRKSFEAGDFDDAVRAAHLLL
GTAATLPDWFLKPVWQPAAPRAPRVLPPGRHTLVLACDGPGTHGLADRLARALRADGARC
TVVTEGPSYERLDAARYRIRPAEDADHTALLRDLAADERPVDAVVHLTAPHGGDASPDES
AARTLLALARALGTRPADLLHVTVDAQAVGAGGAPSPAQAMAGAVLKSLREESPGLRCVH
LDVERDTDPVPLVTAEAAQQSVDAEVAHRGGRRHVRRLAPLPEAPDRREPPATDGFHLVS
GGLGGVGGALAAHLLATPGARLLLLGRRPLPEDDGTHQRLRELGDVRYACADVTDEDQVR
AAVDGAAEAWGVPLTSVWHLAGALVERPVGDLDPDAWRSALDAKAHGAWTLHRVSADHPV
TSFVLFSSVNGWFGGAMNTAYAAANAYLDALALHRRARGLPAQSLAWSMWHERGMSSGYG
LTALTEARGYRVLDAAAALRSLDLARTLDEPHLLIGADRTAPWVRSHVAEPARQVRRLAA
RVALEEGADLGALHRAAADAAGVAPWVLRAAGSAERPAAADDTGGRIHALELRLAELWCG
VLRRDRVGRDENFFDLGGNSLLLVGAQSAVNQEFGCELTVVDLFAHPTVRDLARHLAGRT
TDPGAPTEGAGDPPSGLDRAKEQARRQRAARTRRSARNGKGQGHA
>K5BFJ9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium hassiacum (strain DSM 44199 / CIP 105218 / JCM 12690 / 3849)|TrEMBL
MSRIRSEAVFSDGALPDGRVAVVLSAHAEELLGRDAAAITAYLERHPQASPAAVAATVLR
TRRIRRHRAVLRAGGRAELLDALRAVQAGQAHPLVARSSRTSRAATAFVFPGQGNQWPSM
GAEAYRRLPGYRAAADACAAAFTAAGHPSPLPYLTTGSGDWSQTEIQGAQFTHAVGLAQV
WRSVGIRPDYTIGHSLGEVAAAYVAGAIALPDAVAVVAARARAVERLAGGYAMAVLATPV
GDAEALIAETRGWLEISAVNADASVVIAGERTAVADLVAAAERRGVFARLLDVDYPGHTS
ALERVRDDLLGLLPAGEFAAAPFIGSTTGEEVPAGTGFADYWYRNLRDTVRFDRAVGTAR
RRGAGVFIEMSAHPSLLVALGDLVGDEAVVIGSGQRDAPFADTLAANIATAAAADPQFTW
PVPTGPVGAPLRGFPNAPMRDVHLWAMPKPLPPVHRVVTAAERWDPVTHRGGPVRGRRIA
VVELAVPGSPLAGRLRAAVTGRAELADPAGADLLIAVAPLLDHPDPAEAVDRLADLLGAG
LLDYADHIGTACREVWLLTVGGEQVRAGEPVALPAQAALAAMHRSLGFEHPEQAFRHLDL
PSWDIDAATAVTAVDAVLGPPSVHELALRETSFGPQLFVRTPPEDAEPGAAWPLTEATLA
DVVITGGSGALGRHFARYLARRGARRIVLLSRGGLDPAALADLTATGAEVIAPQCDLRSA
EQLAAVAADHAGAGASLLIHAAGAATFGDHRGLTPAAFADTAAAKVDGLTRLLDHWPLRP
DARILLCSSVSGLWGGRGHIAYAAANRLLDVLAGQLRAKGRHAVAVRYGLWRTDGVRSTI
TDRAGIAAIEAAGLVPMPPEDAIAASLRAHPGDPLVYAADQDRLRLFLRQEPVKTRHRPT
DPTPAADPDPDTPAVVRAEVAAVLNLDAATLDLQTSLLDLGLDSLLALDLRKRLLRATGT
SVPLATLLGGITGAELIAGLDTRSQKVETTRD
>A0A0F7HG83|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Serratia fonticola|TrEMBL
MIQNVVLSGWGVTSAYAPDCPALIKGLSENRLASTQPWFATESEWQDLRLSCNPHHVADP
QPAGTTFTRLQPVINQALAGAGMTTDQLQGKRVRVYLVGHGERPDIADFMGYQERNDQEE
LRLFPKIKRLHAKSYGQDRLARQLTQSYQLSWPPVSLYCASNSSLAAVHLAHSAIAANEV
DLVLVVGWFETMTQDIVFLGGQDMLGEEGSQPFSSHNSCILPTNGVVALIVESEQHARQR
NFTSPVNLRSSVFCQSSGARGSSSFTADFRTIAQTFERALLEAGLTAQDIACVFPHANGV
IASDKAEAMALQKVWGKCGVPVVSYKGQVGYMESCCGLLDLMLAADALQQRRLLALTTRY
PINDSLQIHVHADSPPLALKRQHILKSGIGLDGSAIAMVISANSEDVDEHG
>A0A653F966|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium smegmatis|TrEMBL
MDENHSDSNLPEGTEPAGRPAPRTDMTVNEMREWLRNWVANATGQSADAIDESTPMVELG
LSSRDAVAMASDIEDLTGVTLTATVAFRHPTIESLATVIIEGEPEPEPYDEDEDWSRTRD
VEDIAIVGVATRFPGDLNTPDEMWEALLEGKDCVTDLPEDRWTEFLDEPRIAERVKKART
RGGYLTDIKGFDSEFFALSKMEADNIDPQQRMALELTWEALEHARIPASSLRGESVGVYI
GSSTNDYSFLAMSDPSIAHPYAITGTASSIIANRVSYFYDFRGPSVAVDTACSSSLVATH
QGVQALRAGEADVAIVGGVNALVTPLVTVGFDEVGGVLAPDGRIKSFSSDADGYARSEGG
GMLVLKRISDARRDGDQILAVIAGSAVNHDGRSNGLLAPNPDAQAEVLRKAYKDAGINPR
DVDYIEAHGTGTILGDPIEADALGRIVGKGRPADKPALLGAVKSNLGHLESAAGAASLAK
MTLALANDKLPPSINYAGPNPYIDFEKERLKVNDTVSDWPRYSGKAIAGVSGFGFGGANA
HVVMREVLAGDLVEPEPEPEPEAKPEKSEADAVYVGGVRMDEYGEFIDEDEPAEGGDAYP
SYDEDSYELPGITEAAQRLLEQAREELEAKEAEEPTKQLVPLAVSAFLTSRKRQAAAELA
DWIDSPEGRASSLESIGRSLSRRNHGRSRAVVLAHDHDEAIKGLRALAEGKQHPSVLSAD
GPVTNGPVWVLAGFGAQHRKMGKSLYLRNEVFAEWINKVDALIQDERGYSILELILDDNV
DYTDATCEYPIEVVQLVIFAIQIALGELLRHHGAKPAAVVGQSLGEAAASYFAGGLSLAD
ATRTICSRSHLMGEGEAMLFGEYIRLMALVEYSADEIKTVFSDYPDLEVCVYAAPTQTVI
GGPPDQVDAIIARAESEGKFARKFQTKGASHTQQMDPLLGELAAELQGIEPKPLTTGYFS
TVHEGTFIRPGSAPIHDVDYWKKGLRHSVYFTQGIRNAVDNGHTTFLELAPNPVALMQVG
LTTASAGLHDAQLIATLARKQDEVESMISAMAQLYVHGHDLDFRTLFPRRSKGLAGALDF
ANIPPTRFKRKEHWLPAHFTGDSSAVMPGNHVATPDGRHVWEFVPRGKTDLAALVKAAAA
QVLPDAKLAAFEQRAVPADNARLVTTLTRHPGGATVQVHARVEESFTLVYDAIVARANGA
GVTALPVAVGAGVAVSGDVAGEGAGASVIEDDEPDAEILQDNLTAGAGMGADFQKWDPNS
GETIGQRLGTIVGAAMGYEPEDLPWEVPLIELGLDSLMAVRIKNRVEYDFDLPPIQLTAV
RDANLYNVEELIRYAIEHRDEVEQIAESQKGKTAEEIAAEQSELLGGASTVAELEAKLAE
AGHPLAAKDSEDSENSEDNAAGAAAAAEASAVEGLEIPPPPTDPTGPGGAPIPPPPSDPS
GPAQAASATDAPAGTVNKATAAAAAAKVLTQEAVTEALGADVPPRDAAERVTFATWAIVT
GKSPGGIFNELPTVSEETAKKMAERLSERAEGTITVEDVLGAKTIEGLATIVREQLEEGV
VDGFVRTLRPPKEGSNAVPLFVFHPAGGSTVVYEPLMKRLPADVPVYGLERVEGSIEERA
AEYVPKLLEMHKGPFVLAGWSLGGALAYACAIGLKQSGADVRFVGLIDTVLPGEPIDQSK
EGMRARWDRYARFAERTFNVEIPAIPYEELEKLDDEGQVKYVLEIVKESGVQIPGGIIEH
QRTSYLDNRALDTVDIKPYDGHVTLYMADRYHDDAIVFEPAYATRKPDGGWGSFVSDLEV
VHIGGEHIQAIDEPYIAKVGAHMSEALNRIEAQASKEDGAK
>A0A1B8P2Y7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Halomonas elongata|TrEMBL
MTRRVAIIGVAHRMPGTTPEDFWQDLRAEKDLVTQVAADRWSHEVFQHPDKRNPGTSVTF
AAGSLGDISGFDADFFGISPREAANMDPQQRMLLELTWESMESAGIPPSQLRGSQCGVFL
GVAALDYSYRYTGDMAAIDASTATGNTSSIASNRLSYLFDLHGPSMSVDTACSSSMVAFH
QACQAIRAGETSMALAGGISLHLHPYGFVIFSKASMLSPSGRCRVFDADGDGYVRSEGAG
MFLLKDYDQAVADGDTILAVVAGSTVNTDGHKQGLTVPNTDAQVALMRQVYERAGIDPNE
IDYLEAHGTGTAVGDPIETRAIGEALAKRRQSPLPIGSVKSNLGHLETASGIAGLAKALY
SLRHREVPATIGIRRLNPKIQFDDWNLEVVTQARPLKQEGRLIIGVNSFGFGGANAHVIL
ESPPETPSPASPPVSDEPLPLKLSARSEPALRAMAGRLADWLRDTDTALYDVADTLYQRR
DHHTDGALLFAADKQDAAERLAAFADPERNPGKRPVIQGRRLDAAQGPAFVYAGNGCQWE
TMGRDLLADSKVFAAAIDEVDALFQRHADFSLRAELEGDNGSERFVRTEIAQPALFALQV
GITRMLAAQGIEPIAVTGHSVGEVAAAWACGALSLEDAVRVIHLRSHFQGLTRGQGEMTA
VGLGAEAIAAYLERPEYCDIHLAGTNSAQGVTLAGPAEALSRLEAELSGQRHFAKRLPLD
YAFHSPAMDPIRDDLIAALAGLHPRQARIPYISTVTGEELDGERLDADYWWHNIRQPVRF
DDAARTITTDGTNVLVEIGAHPILKRYLSEALREAELDGLVIGTLERDVPGPVCLDRAIG
QTLLSGLETDIDHWFPVTGRLAELPRYPWQREPHWMPTTSEALGLLSRHYEHPLLGYRLA
QHTLTWESQLDTGRQPWLADHVVGDAAIFPGAGFIELALAAAARWREATPLDVEELEIQA
PMMLDGQHGRLTRLAIAPEDGRVTIHSREPAVGVEWQLHTTARIMAQSRGLLLERAAPDL
PERAPDLELDEHLAMASRLGLDYGPAFQAIDRAWVEGDSVIGRVRPTPAIEEQLALQHLH
PGILDSAFQLFLPLLARDGLEARGMAFVPVRVGRIQWTPEAGRPTLARARLLKRAPYSFT
ADFELFDEQGRAVAVVSETRFKAVRLTQSAKQSLSHLDVRLTPAPRPWNRQPADLTALEA
AMPRLVDGYVEATGQRYASEVAPLLDRLAEAFAAEALDEELHDGVLGHSRYQALADAHPQ
AHPLLDQLLRLLEDAGRLERGENGWTRVAGDDEIDATTIWRLLAQDYPGHIGPIHRLGRF
GLNLRDLLAGHRDAGDIGLDRDRLTRLNRQLIGHDGWRAIATPLGEALADTLAHLAEGQR
LTLLEAGVSAPALGERLADLVDPDRCDYRILTAGELAWQHAEQLRERQPLIEVESLEAPA
EQPPQGATGQAQLALVSLDVTNRDLSRRLIEALPQRLAPGARVLLLGVAPSAWLDTLLVT
PGLDDEHAAPAACELDDVTELLTRLGAEQVQPLPLEDDAGAYLVHARLPDTLDASEDVTD
SPADYLLVADGANQALAERLAADLERRGHRAALGDESAAARATHIVDLRDTGLERCQQAA
RWASLVEASAEGHDAAPNLWLVTRDVAAIWGDASEPASRPGVSDDAALWGFGRSLANEAQ
GFRVRLLDLPGGDLEESAFEALGAELAAPDDETEVAIDAHGTRFATRLRILPAPGTSTAA
PEAPRNAMTLGFPLPGQLRHLAWQPTALPEPGEGEVEIRVEATGLNFRDVMYTLGLLSDE
AIENGFAGPTLGLEFAGVVERLGPGVEGVAPGDAVLGFGPASFSDRLIASQHAIAPLPDN
IDFAAAATIPTTFFTVYYALKHLARLSPGEHVLIHGAAGGVGLAAIQVARWLGAEIHATV
GAEEKGDFLRLSGIERLYDSRSLTFAEEILADTNGRGVDVVLNSLAGEAINQNLRVLRPF
GRFLELGKRDFYENTHIGLRPFRNNLSYFGIDSDQLMKACPELTQSLFSEMMALFEDGTF
TPLPYTAFGNRQVVEAFRYMQQARQIGKVVVTQDQPLRAEAAETETLAAPELPADATYLV
TGGLGGFGLRSAQWLAERGARHLVLVGRRGAASPEADEGIARLEAMGVTVEAAACDVADR
DALAALLERCRAEHPPLKGIIHAAAVIEDGLIRNLDDERIARVLTPKIEGARHLDALTRN
DELDFFVLYSSATTLFGNPGQASYVAANHWLEALAANRRAAGLPATCVRWGAIEDAGFLA
RNTRTRDALQERLGGSALRADDALEVLGRMLAAPGPSLGVLELDWSALARSLPTAETPRF
SEIARTAGDEGQQDDADQDLARLLDELSPEELHATVTELLKSELASILLVEEDKIDVHRS
VYDMGFDSLMGVELMTAIESRLGVRVPVMVLSEASTLDKLSGVLIERLTRGDDEEADDDA
ELASLAARHGTEAVPEVAQEASAR
>D7AWH6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardiopsis dassonvillei (strain ATCC 23218 / DSM 43111 / CIP 107115 / JCM 7437 / KCTC 9190 / NBRC 14626 / NCTC 10488 / NRRL B-5397 / IMRU 509)|TrEMBL
MATDSAQNTKLVAALRSALKENERLRGRNRELDRRSDPVAVVGMGCRLPGGVDSPEGLWD
LVEQGTDAIGPFPEDRGWDLDAVLGGSEPLSAMDQGGFLEGAADFDAAFFGISPKEAAAM
DPQQRLLLELSWEALERAGIDPSSLAGTPTGVYVGLMAAEYGPRLSDAPEDGHLLTGTMP
SVASGRIAYTLGLAGPALTVDTACSSSLVALHLAVRALRERECSLALVGGATVMGTPGVL
AEFSRKQGLSADGRCRAFGAGANGTGFAEGAGALVLERLSDARRNGHRVLALVRGSAVNQ
DGASNGLTAPNGPSQVSVVRAALDDAGISPDGVDAVEAHGTGTTLGDPIEAQALIEAYGG
ERGAPLLVGSLKSNIGHTQAAAGVSGVVKAVQSLLHGTVAPTLHAEEPSTHVDWDSGAVR
LATRAHPLPDLGRPARIGVSSFGISGTNAHVILEAPPAEAADTGAPASARESGPVPAPRT
LPFVVSARGEEALRTQAARLSAHLGAAPATDPGREPEGGPGEHAALVATARALATTRARL
EDRAVVLASDTGGLTAALDALAEGRPDAALVRGRADTGGSVAFVFSGQGSQRLGMGRGLY
EAHPAFARALDEAVDALDCHLPRPLRTVMWAREGTAEAELLDQTLYTQAGVFAVEVAVVR
LLESLGVVPDHVVGHSIGELAAAYAAGVFTLEDAAALVAARGALMQDLPEGGAMVAVQAE
EREARQAVARSGGQLSVAAVNAPDSVVLSGEETAVAALADHFARQGRRTKRLTVSRAFHS
PLMDPMLGAFARAAERVSYHRPVLPLVSNLTGARAGEEVREHGYWVRHVREAVRFADGVA
HLHKAGVTEFVEVGPGGVLSSMVQSCLGGDRGARVTALLGGERDEQRGFAEGLAALHARG
AHVDWSAYLPPGPVTALPTYPFQRERYWMNPPAGGRVVVETGAGATAAGGGAAPGARADL
TALGDDERTEALLDLVRRESAALLGHASPRDVRSDQGFLEMGLDSLGAVRLGERLSAATG
LDVSATTVFDHPEPRVLAAHLSAELAPEDIDASQAAGGDERVRAALARIPVDRLRSAGLL
EALLALDTGVAAGDAGEDGAAEEEGANTDVDSMDVDDLMRMVYGRD
>A0A2P9FCI7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MA5143a|TrEMBL
MHHPLRHAAPHVPRRQLTPHLEESDARMSSTADEPGTATESKLREYLKRAIADARDLRER
LKRTEDRVREPIAVIAMACRFPGGVLSPEDLWRMAADGVDAIGPFPRDRGWPLDDLYAAA
DGDSSSTTLEGGLLGDPAGFDAEFFGISPREAQAMDPQQRLLLEVSWEAVERAGIDATVL
RGSRTGVFFGGGSEDFAGLLAICRDSAETPSLTGVTSSVMSGRVAYTLGLEGPALTVDTA
CSSSLVTLHLAVQALRTGECDLALAGGATVMATPGIFPEFARQGGLASDGRCKAFADTAD
GTGWGEGVGVLMVERLSDARRKGHPVLAVIRGSAVNQDGASNGLTAPNGPSQQRVIRDAL
ANAGLSPADVDAVEAHGTGTRLGDPIEAQALLATYGQGRPEDRPLWLGSVKSNIGHTVAA
AGVGGVIKTVMALRHGVLPKTLHVDRPSRHVDWSAGAVELLTETRPWPETGRPRRAGVSS
FGISGTNAHVILEQGDESPVCPPEEDISPRPLPWLLSARGETALQAQAARLHAHLTDHPH
TRLQDIGLSSTVARAALEHRAVIVGTGRDELRRGVAALAEGRPDAGLTRGRVSDGPGAVF
VFPGQGSQWVGMAVELWEASPVFAERMGECEEALSAFVDWSLREVLSDEAALGRVDVVQP
VLWAVMVSLAEVWRSFGVEPAAVVGHSQGEIAAAVVAGGLSLADGARVVALRSQAILALS
GKGGMASVQLPVVEVEQFAPVADGRVEVAAVNGPSSVVVAGTPEGLDEVIVEAEARGARA
RRVEVDYASHSAHVEQIHDELLDLLGGLEPTASRVPFFSTVTADRFDTSGLDAEYWYRNL
RSTVRLESTVARLVEAGHTVFVEASPHPVLAGAVQETAEAAGRDVAVTGTLRRDDGGMER
LLLSLAEAYVHGAPVDWRKCYAGTGARTVDLPTYAFQHRRYWTELPVARFGDAALAGLGA
AEHPLLGAVLEPADGDRTVFTGRLSPQEQPWTADHAVHGTMLLPGTAFLELALWAGERTR
APRVDELVLEAPLLLSESEPVRLQIVVDGPEEDGRRAVRFFSRAESTGQEWTRHGSAVLS
GAEQPEFDLGAWPPTGAEPVELAGLYEKMATAGFGYGPAFRGLRAAWLRGDEVFAEVEID
PVGTDGQDFLAHPALLDAALHAAGLLPGTLDSGARLPFSWSGVAMYATGATSLRVRLAPA
GADGLSLHAVDALGAPVLAVDELAFRPVSPERLSAAAPGGPDGLLRVEWPELAVRAATAG
TYLWLGGDEAEGTRTYGTVAALDAALTAGEPAPSAVVVRCPVTADECDPAEAAERATTWG
LDLLRQWLGGTRAADLPLVVVTRDAAPVPGPPTTATGTAHAALVGLLRSAQAEEPGRVVL
VDVTGDEPPDPASLDAALAAAEPEVALRGGTVHGRRLVRAGGEPGLLRPPAGHTQWRLDV
TEPGSFGNLALVPTAEGTGELAEGQVRVAVHAAGLNFRDTLIALGMYPDPAPLGSEGCGV
VTEVGPGVTGHTPGDRVMGTLDTPFAPVSVADARLLAPVPDGWSNAEGAAATVAFLTAYY
GLVDLGGLRAGQRILIHAGAGGVGSAAVRLARHLGAEVYATASRPKWHALRAAGLDDTHI
ADSRTLDFRDAFLTATDGRGMDVVLNCLAGEFTDASLELLPRGGRFVEMGKTDPRDPRRI
AAERPGAAYLPFDLAEAGPERIQEILRELGVLFTDGTLTPPPVTCWDIHRAPDAFRALAR
ADLVGKAVLTLPGAGFTADETVLVTGGTGTLGALVARRLVTHHGARRLLLLSRSGPEPDA
ARTLCAELAAAGADAEVVAGDIGDADAVTLLHDHLLRRGERLAAIVHCAGTTDDGALASL
TEERVARVLRPKTHGARNLRRLTGLHPEVRRVVLFSSAAATFGSPGQANYAAANAFLDAL
AHRWRAEGLPAVSVGWGLWEQASGLTAHLDAADHQRLRAGGFRALPTDEALALFDEMLLG
PVPGPAVVAAPPDAAALRARHARDPLPSFLRGLLGPSAAPARRRAAGETREPGEALRARL
RALPEERRRATLLAMVRGEVAAVLGHATAALVDTERSFRDMGFDSLTAVELRNRLNSATG
LRLPATLAFDHPRLDALAAHVSDLLGPGEGRAATATDGDEKEAEIRSLLLSVPLARLRQS
GLLDPLLALATGRSAPSAVADAHRPDRGDDIRGMDAEALVKMAKNLSVDRKQQTGTDAQS
WF
>A0A086LSF6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii RUB|TrEMBL
YGSMSRTSGIMGSNDRGDGLTVPLSVEMAIRCRVTKMKEVELSTVWDDEVTDHCFATIVI
ADKKQETYSSLQEVRCRCTERMDVNEYYDMLYDAGLQYGPRFRTIQELYRGEKEALARVH
FVGNVKQDPFESGFLIHPAVLDGALQAAGCLLEQSHSGNKVMVPVSVGSATLTKVEVFQP
CWAHVRLEETKSKAATLNVTIYDEVTREVVASLQNAVLRQVDPSASVVATIPKELLWKVN
WQLVVDGDKEVVGRTPKVLFIGGNIELSEALENAMGSTCKTLSVDALPREKAELQKVLDA
EQWQAIVYVEAVTAGVYDALDVMNAAVRLVQAHYLNLNSGKAVGALWFVTRDTVFRDNGA
DKPGVEIPAHAGLWGLAKAARLEMEVSAGSPISMGCLDVSGADVSSMAQQILHALKSKVL
TMRETEVAVREDGLYVSRLAPQTEVDVRGAIEFHMPERGAISNLVLRPQAFASRLPPEDG
QIELRVRAVGLNFRDVLNVMGLYPGDPGPPGADCAGVVVAVGDNVEHIEVGDCVFGVAQG
CLRTYVTTDSQLLRRMPESMTFEQAAALPVVATTVEYALHDLAKVKAGDKVLIHAVTGGV
GLVAVQLCKRVGATVYGTCSGGKKDAFAKSMGVQYVSSSRDAKAFAEDMRTFLGEDGKVD
VVLNCLIDDFIPESLKLLGPYGRFMELGKRGVWSKEKVAAERPDVQYELIAVDEMMEKDP
IWFGGMLVRVRGLVAEQKIQPLPMHVFDLADTGENGGVAAFRFMQRAQHMGKVVLKIPSP
VEEASKNGSIVITGGLGALGMVVAGWLAEEGARHICLLSRREEAPQPGEIPGWDWLRTIN
CDVQFFSCDVSKYDSIRSVLRTIQTSVAPITGIIHTAGALADALLDSQTPELMKKVYNGK
VQGAWNLNRALEELGLNEQLKLCVFFSSVTSLFGNFGQANYCSANACLDALAQWRRAKGL
CCQSIQWGPWIEQGMAAELKQQVERNGMKGISNEVGLRVLHDAIRQQEKATPVIGCQAIK
WKLFMHRYIEQPPFFTNIEMDLQVTSHDSNTVLRNLPPSERRDYIKAQVAAAARQVLGSS
SPPPFDTPLQDVGVDSLGAVEFRNVLSKKLGVKLSATTLFDYPTLNAIIDHLCEVFGESS
QKDSLSTKLGALSENDLVQEGMAIVSMSCRLPGNSTCPDLFWDMLMRCTDCVCDIPLTRW
NAEEVYSEDPDLPGKCYTRRGAFIENAEYFDNSFFGISPSEVKHMDPQQRLLLEVAYEAF
AGAGLTKEKLLGANIGVFVGACNHDWTYLIQEDKISAYTGTGSAGSVIANRVSYCLGLRG
PSVPVDTACSSSLVAADFAFEKLMLRDCTMALVTGVNLMLTPHLFIAFSKARMLSPDCKC
KTFDASADGYVRGEGAGAVLMLPYADAKAKQMTIQAVVKGTACNHVGRSASLTAPNGPSQ
AEVIRMALRRAGMKPNDLKFMESHGTGTSLGDPIEVNAVRTVFAPGREKTKPLLIGAVKT
NIGHLEGSSGIAGLIKACLVLSRREIPPNLHFKTLNPHINIEDFPVQFVTDFVSLDSVES
TRKKNTAGVSSFGFGGVNAHVLLEEATRDQNATRKEENRPKICFMFTGQGSQYVGMGRHL
YEKEPVFREAITRCVEIAKEYLPLPLLSVIYPSPDERDKMQEAINETLYSQPAVFVISYA
LLELWKSRGVEPDMVMGHSLGEYIAAVCSGVISIQDGLKLVLKRAQIMSRAPSRNGVMVA
CRATAEQVEEAIHTLFGDGEKNVALASVNGLKSVIVSGNQQDVQAVLRQLGAASRAKMLR
VSHAFHSPLVKDTVAPFKRVLETVRLSKPRVMFVSTVTGKVARDELQNTNYWAEHITKVV
RFCDAVQACIAQGAKIMVEVGPRPTLSNMGKGCLPQTTADEVQWINSLEPETLSSAVFDS
LSALAKAGSGAMPAVFDRKFFPWTETCHPLLGGKNTRPDGSVVYSALLRDLVKALFLDHV
VYGKALLPATCLIEMMASATTHMISNHDEEKLVALSQVVFEKPLLVPDDTSLSVLVTVET
RGQVRVASQVSNSEEEAEDHAVCQVNIVDALPAAPALTEIRARCKTEIEASQLYAQLHNV
GLQYGPRFQTIVKVFKGEDEVLGLLQAQNVTNFETGFMMHPAVLDGALQLSAVLAFEKGS
SRAMVPFGVDTVLLKSCPPEKELWARVVMNRKGVSSASATVHLYDFDGEPIAVLMGVTLR
PIEFNTAADIPRELLWEVEWEYAGSYSMPQDGSLATPSGTDDSGAEDVTRTPSPLVTGEN
ENTPSREVPSALPGLSTETPRASKPLSTDETSGAVLNKSVHSVLLVDYAGGHREVVASIR
DTCDVEVEVLSKPGSPELYAQQLRQFAEVVATKTETVPLSTILFLALDEATPAEQLAGGL
LETVKVFAVEKFKKLPCIWVLTSGAQGPTRSVVSPKHAGLWGLMRTVRLELEMQIGKMVR
FGCVDLDKNLEVSVALHFILQKRTEEPFEAEMILRCPSEDSEKEPGTAEVVNRRERSASF
VSVGPEPVVPSTTDASAKSSVTSDRMALTPGALSCFDETANSTEKLIFNAFCPRLHRSPI
PVRGAVELHMPERGAISNLVLRPQAFASRTAPQSHECEIRVRAIGLNFRDVLNVMGLYPG
DPGPPGADCAGTVVAVGSGVRHLKVGDSVYGIAQGCLRTYVTTNGNLMRRMPESLTFEQS
AALPVVASTVEYALHDLAKVKAGDKVLIHAVTGGVGLAALQFCKRVGATVYGTCSGGKKA
AYAKSLGVKYLTSSRDASAFAEDMREFLGEEEKIDVVLNSLIDNFIPESVKLLAPGGRFM
ELGKRGIWTKAQMAAERPDVYYETIAVDTMMQEDTVWFGGMLDRIRDHVDSGNIPPLPLH
VFEMTDPLAGGVAAFRFMQRAQHIGKVVIRIASDLEVKIPSTTEPAATETAMLAEAGTQG
NASIGTSTQQIADRTYLITGGMGGLGLVVAQWLVEEGARHIVLLSRRGEPSDTVKQSSIW
EYLTEKERTCVSVLPLKCDVSVKDDIVSAVKEIEARGFPPIRGIFHAAGVTADASLANQT
REAIEQVYLPKVTGAWNLHEVCESMGLDKNLDMFVMFSSVAALLGNFGQANYSAANACLD
ALAEYRRARGLCAQSIQWGPWIEQGMAADLRQALDKVGMRGISNELGTRVLSEVVRNPRR
ATTVLCQSVIWKKFLQRYERVPPLFKNTRAGQGATADSSLMLRTMTAEERRAYVEKTVRE
VVKQALGLADSPPMDLPMQELGIDSIGAVELRNALSSRLGVKMPATAMFDYPTLDAMVDY
INSTLAEQCAGTEQDVSAETQMNLVPQIMHRLEGNIAVTSVAVHLPGSVHNAEEFWDMMH
QMRDCITEVPLTRWNMYTFFDPDPDTLDTSYAKLGGFIEDADMFDNSCFNISPAEVRVMD
PQQRIILEVAYEAMVSAGYTSSGQASQQSIGCFIGCCNADWHMLDVPSGPFTGTGSSTSI
ISNRISYTLGLRGPSLTVDTACSSSLVAMDNAMCKIIEGSCSAALVGGVNLMLSPHLFIC
FSKARMLSPDCRCRTFDHRANGYARGEGAGAVFLKPLQAARKDDSTILAVVRGSAINHDG
RSASLTAPNGPAQQAVIRAALQSGGVKPADITVLESHGTGTQLGDPIEVGAIKAVFMHHR
GADNPIYIGALKTNIGHLEGAAGIASFIKLVLCLRRRELPANLHFQQLNPHIDMTDFSAV
FPKATVDLPVTRKLFAGVSSFGFGGANAHVVIEEHFELSNATEAPQKQTAPVKRERRSFP
WYQAFHPMLGHETKTEVDERKIDMEIRRDVFDLLAQHMVEGRPVMPAACYLETLTSAACT
SEFLHPCSRKMLRPNHHAAVTLEDIEFQRPMILEAPEGHGHQIFQILTASLGPNGNASIS
SLKTGDEEQFIHATCRLSSVNDTTAFTRTPEENLKFLDEDTNRVPVDVGEMYEKLWKNGL
MLGPQFRTIHSIECSPRTAKVKLQLPQTPTSCELGFRMHPCVLDGTFQTVGPLVLAHDEQ
ARKDGSSSNVGTMKLMIPFMIQRITLTSMHGVSNALWAHVALVKRESNQAIVNIDIMSMT
GEPVCCLKELTMRRLDPVPVAEIPRELTWTVDWEEGQNVDPVPANAVEVVAIDPLGMQHT
VIKELKQKGFASVQVFERDSSVEEVLRVLRISSSGDSPTSLTPASAAAGEAAKSTSLPHR
VVLFLGTGGANDAIEALDCLLQLSSGLEKAAKEDRQQEFYPIWILTKGSQSHRDKGRVSN
PVHAGLWGFARTARLEISAQTSKEASIGCVDLGPECRVADVVQHLAAIQSQEKYEREILF
DEVEEVEDQKREKGKPPSGSKRLKHFVSRLARSPLNVRGALELHMSDRGSITNLTLRPQS
YAARVTPKGDMVELRVRAVGLNFRDVLNVMNLYPGDPGPPGSDCAGTVVAVGDRVKHLKV
GDSVYGVAPGCLKTYVTTNSQIIRKMPASMSFEEAAALPVVATTVEYVLNDLAKVRAGEK
VLIHAVSGGVGIAAVQFCKRVGAVVYGTCSSEKKREFVESLGVKYVASSRDPEKFTAEMK
TFLGEEGRVDVVLNSLIDKFIPASLALLGKDGRFIELGKRGIWTHEQMRAQRPDVYYEAV
AIDVMISENPRWFGIMLDRVRTLVERKQLLSLPLTVFNMNDPNEGGVAAFRFMQKAQHVG
KVVVAIPSALDFERSTVGPPTTPQKTYVITGGMGGLGLVVAQWLVEEGARHIVLLSRRGE
PSDTVKQSSIWEYLTEKERTCVSVLPLKCDVSVKDDIVSAVKEIEARGFPPIRGIFHAAG
VTADASLANQTREAIEQVYLPKVTGAWNLHEVCESMGLDKNLDMFVMFSSVAALLGNFGQ
ANYSAANACLDALAEYRRARGLCAQSIQWGPWIEQGMAADLKALAEKAGLRGISNELGIR
VLVEAVRNSKTVVTFLAQSFIWKRFVQRFDVVPPFFSNIEFETASPGAFRVLYSSMTPDE
LHTYVSNVVLDTARQVLGTSELPALDSPLQELGIDSLGAVELRNSLSQRLGVKLSATTLF
DYPTIRAIIDYIVNQVSGEASAAKATSGALVSAGLAAGRNSPIAVVGYSCRLPQGSETPD
KLWEMLRRAQDCVVEVPLTRFDVDMFYDSDIDAKGKMYVRKACFMDDADMFDNSFFNISA
AEVTYMDPQQRVMLEVAYDAFYSAAYSREHLIGKNYGVWIGCCNSDWHFLEQQSNPDKSS
SYSGPGGSGCLVSNRLSYVFGLKGPSMTIDTACSSSLVAADCGAQAMRFGYCDGALIGGV
NLMLSPQLFLAFCKARMLSPDCRCATFDEKANGYVRGEGAGAIMLRHLADAQREGKRILG
IVRGTAVNHDGRSASLTAPNGPAQQDVIRSALQIGGVDPLDVALVESHGTGTALGDPIEM
GAIKAVYGAGRSADSPLVVGALKSYIGHLEGSSGIAGILKVLLCLRHHEVPPNLHFDTPN
PHMDLSDFHVVLPKKQMKLQPAQKSSTILGSVSSFGFGGANAHVVFEEYPEPTMATDVGG
ERRSTEAAESAGKKRLAFLFTGQGSQYPNMCKQLYEEEPVFRSHMDACFTVLEGKLDVKL
RDVIYPTAENDVEMLNLLNQTGYSQPAIFCVEYALAQLMISKGFSPSVVMGHSLGEYAAA
AIAGVMDWKDALLLVHERASIMQHIDPNDGVMYACRASEQDAQAAVEKVLGEKAVAVTVS
AINGPRSIVLAGTQPDVLAVLKAMDMQSRAKQLTVSHAFHCPLVGEAAALLLPKVESVKL
SNPNEGITFISTVTGKAVGAGELTKPEYWATHITKPVQFLQGMRAAVTSGEAGIFIEIGP
RPTLVNMGQQCVPRNDYTWVAPVDPKDSNRNSFPQALEKITSNMVCTYTWKRHAFPWTVV
VHPFVDKFVPDQDETKATSQKLLTPAVGELLHDHVVNGTAMMPGVGFLEAMAAGGFMMLD
GKLPSTVVALRDCEFERPMLIPKIDPSTGEFTQAAKLMITVNNKDITLKSIMDGEEEEIF
HSRCTFSLCPATSLPTEPPDLLTSLQGRITTPVPITTLYETLQSVGLQYGARFQSIRECY
AAASDEVLAKLRPKLPLHSFERNFRIHPVLLDGALQTAAVLFAEMGHKRPLVPVGVKRAL
LARVPAGSEVWSHVVVKSKDLRSATMDVTLFSTKGTILGQLVDVAVRAFDAVAGAQIPKG
LLWEVSWVPKAKAPVEDGVDTVENEASETITPTAKLAVKPTGKVEGLARQPAVNGQPKWL
LLKTPSSMLEGLQKALQGTPSAFVKELDEKHPNNAISSKIHNSEWDAIIYLGALSAAASS
TTCVADALLLANTLGNTAAEKPLPNVLFVTQGQHFIRECGDVPTTAVPTQTGLYGFCRSA
QLELENIIGRPVYLGTLDFAAKDPTLDDPAAFVSALQRVLAEADPTGAAGTCEPHTVIRG
GKEMVPRLVKSSIECRGAVELHMSDRGALSMLKLRPMPKSARVPPPRDCVEIRVRAVGLN
FRDVLNVMGLYPGDPGPPGADCAGTVVAVGEGVEHLRVGDAVFGIAQGALKTFVTTSAHL
VRPLPGRLTFEQAAALPVVASTVEYALHDVAKVKKGDKVLIHAVTGGVGLAAVQFCKRVG
AEIYGTCSGGKKEEFARSVGVKYITSSRDPKKFAEDMCEFLGNGKHKIDVVLNCLIENYI
PETLKFLAPNGRFVELGKRGIWTREQMGTVRPDVLYETVAIDTMMEEDPVWFGGMLDRIR
NLVDGSMLQPLPLHTFEMTDSSEGGVAAFRFLQRAQHIGKVVIRLSSALEVKNFTTNSRQ
ETENEDSGERHTLSPATAVGKPLSQSVADQMHKTYIITGGTGGLGLVVAQWLIEEGAHNI
VLLSRRGEPPSSVKAGDPVWKYLCGEEQPNCISVTTLKCDVSQKDDLLRVFKEIESRGLP
PVAGIFHAAGVTADAALASQTADSVDQVYLPKAIGAWNLHDACEALGLNKSLEVFMMFSS
VAALLGNFGQANYSAANACLDALAMYRQSLGLCGQSIQWGPWIEQGMAAQLTQHLEKVGM
RGITNELGLRVLGDVMMHPTVAVVGAQSLQWRKFLRRYAFEMPSFFSLVPMAGAGSSEAS
VNLATITKEDLCELISSLAQAVSGAAEKPAVDTPLMDLGLDSLGAVEFRNSVADKVGVKL
PQNLMFENPSISSISDYILDKAAGKHGESGVTGTNGGSGEGSDIPALDTPLDQWLMSVLE
PAERFALYIDSFASEYGTLQKMAAEEDIITALEDLGVEDGGDFERLHVAWDDLCNQINTA
KRMAAKDIRPSSTAVSVSDHPKPRMPHPMEDVDTLLASLDFDVSTLRPATAPDKVKNVLL
TGVTGFVGRVQLASLMQLKQRPDLRVYCLVRARNADHALSRIREATKEAKCWQETFVSRI
VPVTGDFTQPLLGLSSEEFQELARKIDIVYHTGGDVNLLSNYGRLRATNVLSVKAIIDLC
TTYKVKPLHFASTLGQFPAFFAMFTGHFSGESIREDSTPDVSQMENFYPPSRQGYPWSKW
AAERVLEGARKRGLPVAIYRLPNTYVAYKTGYTNKTDYATALMIASIQEGVFPIGAATAP
LTPVDTICDMLVEASFLEKPKHWVYHLFDPRLVTRADLEQWSQELGISYVGVKVDEFLEA
IKKRGPESPVFKFVPLMQHWRRFWFDPEERTESFPISNEHIFEDLPHMRWPSLREVFKNS
LLYSVRMGFFPKNSKSIILDPQVALNEARRICGLQLMGREGEDFFLHPWRVLQESARREC
DLLFGGQLAVYRTVRHYFMNVMYLADAQAKCPEIEKQEIQAPLIIVGLNRTGTTFLQNLM
STDPSNRSLRYCEMIAPYGPDGNYRPKGLPNTEESWKKDPRIPFAQEILDSQLGLSEEWM
AIHTQRAELPEEDFVIFEHCGRCYSICTEFSVPSYREWLASDNYKETRKAYSFHKRFLQH
LQWQRPAKRWLLKMPFHLFTLEALFETYPDAKIIFMHRDPKETMGSWASLVKHAQQSLMD
NVDPSALGREELRAMSTMINRALAFRRSHPELGPRFLDVQYQDLVNNPIGVVKSIYKHFG
IPLTLAAQTGIASFCNENRKHRDKLTKHMYSLKDVDLTDGMVQEAFKEYYDSGLCKYLSS
AR
>A0A2P9F877|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MA5143a|TrEMBL
MLDLEDAAKLVAARARLMQALPAGGAMITTTAPAETVTVLLTERTSIAAYNSPANTVVSG
DAKEIAAIGEALTEQGHRVRELTVSHAFHSPLMDPVLEEFAAVAETVTYREPGIPVVPAG
EGDPLTPGYWVRHIRDSVRFEQAVRALADQGVTTYLELGPAPHLTSAVNDTLDTTACVPT
LRANDPEPRTLLTALAELHVRGTAVDWSALLPGGKHVELPTYAFQHQRYWLDATRAATDA
TDLGLVDPEHPLLGAMTEVPGSGVVVFTAKVSVREHPWLGDPVAASCGLAELALHAARET
GWAGVEELVVEAPLVYLERAAAAHLQVAVDKDGGLTVHSRSDDDPGAPWARHATGTLATA
VLEPPAPFAPDAEYEQLDLPEADHEDAERYGLHPALLAAALHTLRTEANFPSRWTGLRLH
AAGATRLRALITPAGDGRVSCRFADATGGPLASVDSIELAPAPTTVSPAESLYRLTWTPS
QAPTTPVDATATIASPQDVRRLAAAERVPELVRLDLRDAIDQPDPAAAHTLTTRVLDLLQ
TWLAEPALEETHLLVVTHGAVATTADEPVTDLAAAAARGLVQSAQSENPGRITLVDTDAV
SEKAVVDIPAGEPQLALRAGVPHAPRLVRAEVAPREPITLDPDRTVLITGGTGSLGRLLA
RHLVTGHGVRDLLLVSRRGPDAPGADDLHAELTALGANVRIESCDITDRDALAGLLTGTP
LTAVIHTAAVFNNGVINSYSADRLKQVLTPKVDAAWYLHELTRDHGLDAFMVFSSATGAV
LGAPGQGGYAAANAYLDALAEHRRTLGLPTTSLAWGLWEQARGLFTHADLQRIERAGMVG
LSDQQGLKLFDASLSTDEPVVIPTKLDFAALRALGAKGELPAVFGELVRTVRRAANSTPE
ATDDLAARLAALSDDDAQRHLLDLVRAEVAVVLGHASAADIESGRAFSDLGFDSLTAVEL
RNRLVSRTGIRLPATLVFDHPNPTALARQLKDELTGGGATAAARTGDGRIATTAADEPIA
IVGMACRLPGGVRSAEELWDLVAAGRDAVTGFPSDRGWDLDALFATEPDRTGTSSTREGG
FLTDAGGFDAGFFGISPREALAMDPQQRLLLETSWEAFEHARIDPVGLRGSDIGVFAGVT
HQGYGAFPGDVPKELEGFMVTGASSSVVSGRIAYTFGFEGPAVALDTACSSSLVATHLAV
QSLRAGECSMALAGGAAVMVGPGAFVEFSRQRALSADGRCKAFSASADGTGWAEGIGMVL
LERLSDARRKGHRVLAVIRGSAVNQDGASNGLTAPNGPSQQRVIRQALANAGLSPSDVDA
VEAHGTGTTLGDPIEAQALLATYGQDRSQDRPLWLGSLKSNLGHTQNTSGVAGVIKMVQA
MRHGVLPRTLHVHEPTPQVDWSAGAVELLTEARDWPEVDRPRRAAVSSFGMSGTNAHLIL
EQAPEPEPDDEPAAVDEPHVVALPLSARSRGALGDQARQLLEHLREAGPRLVDVGHSLVA
TRATHAHRAVVVGTGAEQIRAALGALARGEEHPGVVTGVAGAAGSDGKVVFVFPGQGSRW
VGMAAELLESSPVFAEHLRACAEVLNPLTGWSLLDALRGGDLERVDVVQPATFAVMTGLA
VLWRYHGVVPDAVVGHSQGEIAAAYAAGALSLADAARVVALRSQAIAERLAGLGGMIHLT
LGREETAELLTSWQGRLEIAAVNGPASTVVAGDIDAVDELLAHCAGEHVQARRIPVDYAS
HTHHVEGIREELLTALDGIEPRAASVPLYSTVDGTWLDTTVMTAEYWYRNLRRTVGFHTA
IESLAAQGHRVFVEASPHPVLTHSVQDTVEGALATGTLRRDQGTLADFTAALARLHTGGV
PVTWHHESTTTVDLPTYPFQHEHYWLEATPTGDVTAAGLSTAEHPLLAAETELPDSGGRL
FTAQLSLTSQPWLADPAVTGAALVELTLHAATAVGARSIDELVISTPLLLPGQGAVHLHI
TTRPARDDHRHTLTIHSRAAADPGARWTLHAEATLSQSTGVTAVNDSDASEAVLPDELTG
DAEHYGIHPALLAAGVPASVTGDGTPLLPLRWKGVTLHATGATRLRVRTGSASEQEGVAY
ELADTTGEPVLSVAEVTLLPVRAESLEVYEAREARQLAYHLAWTETPADAAARDDARPVL
VESPDALRELAAAPPALLRLDVRGGDAASVPEATGNVLSMLQAWLGEPALDDTRLLVTTH
GAVSTGDDDPVRDLAGAAVWGLVRSAQSEHPGRITLVDVLGSLDEERESGLATGEPQAAV
RDGRTYVPRLVRADMPPVPAAEPAPDTSGTSRTPATGPLNSPLDPDGTALVVGGTGALGR
RVAHHLVTRHGVRNLLLVSRTGPDAPGAKELLEELTAAAEALGTGDAHIRIEACDAAERT
ALAAALDTVPATAPLTAVVHAAGVLDDAVITTLTPDRLTTVLAAKADVAWNLHELTEERG
DRLDAFVLFSSAGALVLGSPGQGNHAAANAFLDALAQHRRAHGLPAVSLAWGPWTDGMSG
RLDGTAKQRLTRGGLAELTPEQGLALFDLGLGAPDAVTVASRLASAALRSQAANGTLPAV
LDELFPRLRRAAGTAEADSSKSLAARLAELEDTERREYVLRIVCGQAATVLGHASPDGIE
ADRAFNEVGFDSLTAVELRNRLATATGLRLPATLLFDHPTPVALVEHLLAEVAPEDDEDP
ILTELDRLEALAAALPPEHIEHIRQTGIVARLQTLTAKLNGAGPATAVADRLEDASVDDV
LDFIDSEFGNA
>D3Q135|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)|TrEMBL
MDKTSTEDKLREYLKRATVELGQTRKRMQELDRRATEPIAIVGMACRFPGGVTSPEDLWR
LVSQGTDAVGEFPEDRGWDLDSLFCDDTSAHGTSYVSEAGFLDGATEFDAGFFGISPREA
YTMDPQQRILLEVAWESLERAGIDPKTLTGTEVGVYAGSIGQDYGYRLGQFDQSLEGQLI
TGNTGSVVSGRIAYALGLEGPAVTVDTACSSSLVALHLAARALRAGECDLAMAGGVYIVT
SPAPFVEFSRQRGLAKDGRCKSFADSADGTNWAEGAGMLVVERLSDARRLGHEVLAVVRG
SAINQDGASNGLTAPNGRAQERVIRRALDDARLAPSDVELVEAHGTGTTLGDPIEARALL
AVYGQGREPDSPVWVGSLKSNIGHAQAAAGVGGVIKTVMAMRNKTMPPTLHIDEPSTHVD
WSQGEVALLTESRDWTVADEPRRAGVSSFGISGTNAHVILEESQTDTMSTPDDAVTPEAV
VWPVCGRTDAALAGQAEKLLSHLGEDFDPVSVGYSLAATRTPLDRRAVLVGGDRETLRRG
LTALANGDNAPGLVRGNVSEASVAFLFTGQGSQRPGMGRQLYRRYPVFAKTLDEVCDALD
PHLDRRLRDVLFGADTEAVHQTGYTQPALFAVELALHRLAESWGLRPGAVAGHSIGELAA
AHVAGVFSLPDACALVAARGRLMQALPRGGAMVAIQATEAEVTPLLEERVSLAAVNGPSS
VVISGDAEAAQMIAAKFDAEGRKTKNLTVSHAFHSPRMDDMLADFAEVAATIEYHPPRLP
MVSNVTGDLERARVASADYWVRHVRQPVRFADGVRTLHANGTTMFVEIGPDAVLSGIGVE
SATDAVFVPLLRGARPEERTLVSGMAQAWTRGAPVELTRVFDGTAASRVDLPTYAFQHKR
YWPKAEAFANTEPAVGAPTATLPADAGTPAPDLAGRLAVMPEAERHRVLLNLVRTETADV
LAHDTMDDVTADEPFKDLGFDSLSGAELRERLASLTGLELPITLSFTYPTSRALADYLAE
EIRAAQPADADPIDALLTELDNALSATSDDPDRRTRVTGRLESLLAKWAVDREAATNSGD
SFEEASDEEMFAMLDRQLGER
>G8NU16|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Granulicella mallensis (strain ATCC BAA-1857 / DSM 23137 / MP5ACTX8)|TrEMBL
MIQDHGVAQSILEMIQARAEQQPDRTAFIALEHGEREIDRVSFSELDLRARSVAARLQAS
SKFGERVLLLYPSGIDFIASFLGCLYAGAVAVPAYPPLKNRFADRLHSIVQDCRPSTILV
DSATLHSMERRSNDLSAVGQIPVVAIDRNSPQAAAGWVRPAVDGGTLAFLQYTSGSTGIP
KGVMVSHGNILANVRQIASCVAAGEDLVSVSWLPLFHDMGLLGTVLLPLFAGGQTVLMDP
AAFMQRPARWLHAITKFGGTACAAPDSAYLLCAQKVSAEEKAHLDLSSWSAALSGSEPVR
ASTIERFTREFSPCGFNARAMRPVYGMAEATLFIAGQPKDTYPLLQRFNTDQLSHGIAVE
SADAGAQQLVSCGSTWGEHALKIVDPETRTLCRAGEVGEIWFAGPSVGKGYWRREEESKE
VFSAHIEGGHSDENVYLRTGDLGFLNGDDLFITGRLKDLIIVAGRNLYPHDLERTAEDAD
PALASHAAAAFSVEEDGEERIVLAIEVRREAMRSLDSEATASAIRRALSEEHGASLHAVV
FLRPASILRTSSGKVQRRQVRTAYLQGVGLEIIAKWQKLNTVVPEVSSRSERSNLEMWLA
ARISRLAGIPMQELDPWQPFSTYGLNSSDAITLSGELEEYLGRPFMPTLLYDYPSIALLA
QRLNEQPVDEIRAMHGSENEPIAIIGMGCRFPGANNPEAFWQLLKNGQDAVAASPRRVMG
LPPTGMLEEVDRFDAELFGINAREAEMMDPQQRLLLEVAWEAIEDSGIAPSSLAGSRTAV
MVGISGSDYARLIWQASADISPYATTGNALSIAANRISYVFDLRGPSWSVDTACSSSLVA
LHQACQALRRGECDTALVGGANLILVPQLSAAFTQAGMLSPDGVCRAFDEKANGYVRGEG
VGVVFLKRLSEAIRAGDRIQAVVRGVAVNQDGRSNGLTAPNGPAQQAVIREALREAGVKA
CDVGMVEAHGTGTRLGDPIELNSLIEVLEENRTQDDLCWLGSVKTNIGHLEAAAGIAGLI
KATLALRHQEVPPHLHFTSMNPYIAIADKPFHVPQDVMRWKAGTAGRIAGISSFGFGGTN
AHAILAEGPVRSERAVVQQHRANLLAFAARTPEALGKIADSYAEFLKKHPETQLEDFAYT
VNRSRSFLAHRQAIIFSSREELLTKLAHREKPRATSVRRRIVFHFCGEYGAGETAHELAT
MLPAFRKLLGSEPGELETRAISVSDVQSVLAQLWVRFGVRPQAISWEGIGKEAALVFATS
LDESVLFLESSEMCQEADWVLPISPSAACWTSILDQLADFYLNGGNVDWAVLASNIQPQQ
LGLPTYPFERNRYWIEAFTQEHSLPGNVKADEHSDAVLYRRHWELLKSTPGPRSASVGHW
LILADSGGVGAQLAMELSRKGNTCSLISEVEVEKLSLNDQTLQGVVHLGSLDLEPTDMAG
RSKVSSSVLALVRMLKGNLASGSKTHLWLVTAGAMPILEQDVPAVSQAALWGLGQAIEAE
HPELWGGLLDVDPARPSACLLDAIEGRFGEARLALRDGQRYAAKILHDHQPMESNLPPGF
EENATYLITGGVGGLGTRLTKWLLERGAGNVALLGRTVPQQSVNEKTRFFRCDLANTDET
MAVVREIENSMPPLKGIFHLAGTLDDGLLLAQDGERFYRSGAGKAEGAWNLHLASRDIAL
DHFVLFSSMASLVTLPGQGSYAAANFVLDTLAHHRRATGKPALSVNWGPWADLGMAATEY
GRAAVERMSSFGVAALPADVALTMLGQLMSSGAIQIGVTQLASAKLSRKSVSAITSSQLA
GLPTERHEGLDRDTEFVIALRSCASVDRFDWLAARLLEIFSETLRLPNVEAITSTQSFLE
MGGDSILALELTNRLSSTLGRTLPGTLLFTFPTIAALTDHLLRELTMDLGTADIEEDSRD
LNEEELTELIAKEIGGK
>A0A2S8BBP6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium talmoniae|TrEMBL
MILVDAAAGACPRRAAADLTDGRSVEVCAPACDITDPDVVAAAAAAHAGAGASLLIHAAG
VARFGPHHRLTAADRAAVFGAKVAGLARLTEAWPLRADARILVCSSISGVWGGHGHGAYA
AANRMLDVLTDRLRDRGWDATAVRWGLWQGAGIVDAAEITRIERSGLLAMDPDEALEASL
RRHDGDPLILAADLDRLRVFFDSQGSPLPLAAAENPPAAAPTEQLPVAEAVPCRVGRRR
>A0A099KPM6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Colwellia psychrerythraea|TrEMBL
MTSEKTPEINAQLSAEPIAIIGMGCRFPGKANNPDLFWDNIKHGVDCLIETPQSRWNKDT
HYSAVKANKGKINSKWGGYIEGVDEFDPSFFGITPREAEHMDPQQRKLLEVAWEALEDGG
QQPSKLAGTSVGVFMGGFTLDYKIMQFTNPDFDNIDAHTATGVMMTMLSNRVSHVFDFTG
PSMSIDTACSSSLVALDMACKSLQCGASSMALAGGVLIHLAPQYTVSESKGGFLSPTGFS
HAFDSSANGYVRAEGTGIVVLKRLKDAIADGDPIHAVILASGVNQDGHTQGITVPNGDAQ
LALMKQTYKNAGVNPGKVQYIEMHGTGTPVGDPIEAKSVGQLLAIDRDSKDKCFIGSVKT
NIGHTEAAAGMAGLMKTIKAMQNKQIPPHLHLKSINPKIDYENAVYEIPTRLNSWPKHEG
LAVAGVNSFGFGGTNSHVVLQEYITPPINKIAPTNPEAYKLLPLSARDEEGVVRNAKAYL
SFVEDNSERLDDIGYTAAIKREHHQYRSAILYKNDIELSEKLRQFSQDPELAKNNTLRTL
KTKENKIVWVFTGMGPQWWAMGHELYQSEPTFKNVIDQCDLHMAKYADWSLKEEMFAAES
ASNMQYTWLAQTANFAVQIALAALWREKGIMPDVIIGHSTGEAAAFYEAGVYSLEDACKI
VVHRSRLQHSCRNTGKMMAIGLSDIEVSQYLNDQVEIAAVNSPNSVTLAGEESALNAIAE
RLEAQGVFCKFLRVEVPYHSKFMEPIKAELLSCLDDITANEAHTPLYSTVTGNIAQGPEL
NAHYWWLNVRQAVRFVDAIRNLIDDGLRTYLEIGPHPVLGGSITETFEEKDVQGNVLSSL
YRKADEQTHFYNSVAQFFQLGFNIDWQAIHGIATYIHLPTYQFRTERYWTEPEYFNNLRQ
GKNVHKLLGRKRSEAEHVWDCNTSVERDTFLSDHQIQGNTIFPAAGYIEMAYAAAENVWG
PGCYAIDNLIIDKALFLNNEAAPKAQYILHNDNPVFRIISSDDQSTNNQSIKSQVTQHAR
GKLRRVQSSSLSDNVALETLKSTASAMQNHEEFYAHLHEFGYEYGPCFRAISEIYQTQDG
VLAKIEWPQALKKNDEFHLHPSLLDACFQTLVHTELNTADANNFSIRLPVMLSEICITKN
TVNSFWCYTKITQRDDDKTVGDLYLCDDNGVTFGYIKGFIAQSVDSAASGITTRTIDSWL
YDINWLAQPKQVSEEALDENETQAKSEIDSQQWLILADDAGIGQAVAQSLIALKQPCCLV
SVGEYFDYDAEQNHAWLVPDSKDHFLQLFDTLGKDNIRGVVHCWNLDTPDLDSLDIGQIQ
RAKRLAIHSALNLTKAINTANVKFPLYFITRDASQAPATNKANVLSGSLTGFCRVLAHQE
LVQNFGRLIDVDGINDVENIVTELNADSTEHEVAYRDNEAFVPRLEQAQELQTPFPTVLK
SDAAYIITGALGSIGQLVCQLLIDRGAKSLILVGRSKFPVKEEWASLTPDHTSYERILFI
RSLEKQNINITLWNADITRERDLKRCLNEYAQKDSPIIRGLFFCAGVVKDTLLDKMDTAA
FDAVFDTKALGAVMLHRALSKTQLDHFVLFSSVAAQVTTAGQTNYATGNAFLDSLAHARR
QDDLPALSINWGPWAIGMIKELNLADHYKNQRGMNCIQPFSGMAVLDRIIDLDNAQLMVC
DADWSVVTNWYEGKPSLFSHLSQKKSGSQNDKKQAFGPLYQQTEVVQRQVLVADHFASAV
SHVLRCKRDQVELDLSLGNLGIDSIMATELRNKITTHFGETLTIVRLLSGATVNELSAEL
NDKLIETHGSHVLSGEDDVVDAEINAEGTTSSRLVLKTAHSAIEAEFPLSYGQKAIWFIN
QLNPDSASYNIGGAMHIPAELNIDALKKALSEVVSRHPMLRTNFFFKDSEPYQRVWQSRD
DALTVIDVENKSWEEIQQLIVTDNERPFDLANDPLFRLNLYRQNDQSYYFAVAIYHIISD
AWSNYMFIDEMQALYAHHAKGDSLDLAPVAGSYENFVNWETRLINSARGGAMYRFWQNHL
PETVPVLDLPTDKVRPPVVTNVGASYQFELNPRLTEQLISVAKQNGATPFMALLSIYYTL
MHKYTHQDEIIIGSPVAGRTSPDFANVYGYFVNPLPLCARFDQETNFENLIAQVKGITLS
ALDNQEFPFALLVDRLGIEHDPSRSTVFQVLFVMLNHRVEQSHMDENNVAYYKGFPMQFM
ELPEEEGQFDITLSTYEENGVFKATFKYNTDLFELDTIERMAEHYLQLVSAFVSTPAKPI
HQVSLLSNNELEHLSTQLPNCINDDVLIHQLVEQAAVKFPTELAVSYANEAGFLDSITYE
QLNNQANQIAQVLHEHSGLKELDNAVIALQFDKSVALITMILAVLKSGHQFLVLDPELPA
ERNKTILQQSKTALVITQDHTEVEEVISIDWGTINTLGKAHSTDNLSLSLAADALAYMVF
TSGSTGVPKGVQVSHNNWRSIQAAWHQEFDLADTTTHLQMASPTFDVFCGDFVRALCSAK
HLVLCSKSLVLNIPALYELIVNEQVDCAEFVPSVVRNVILYVQQNNLSLHSFKRLMVGSE
QWKVSEYTQLKGMLTTDARLFNTYGTSETTIDSTYFEGECEGLSPASVVPIGKAFNNTTV
FLLDKHGQPVPQNIIGEIVIAGEGVSRGYINNEEQNNSQFVELTIPGFEGVLAYKTGDLA
KKDRVNNLHILQRIDDQVKIRGHRIELGEVESSLSAISGVVRSWVKGDTINGKIELVGYY
QLESGLAIEQSFIVEQIENQLPNYMVPSYLIQLDSFPELSNGKINANKLPTPDVGTQEKL
VVLPSTMYEVELAKIWSNMLGTKNLSIHDEFFLLGGNSLYLIELMIRIQHTFNIKMEVSQ
LFRFTTLHGMASAIEDVVTGKEEGAQPYLAFNPQQKNMLFAFPPAGGYSIVYQALATELS
DTQIVSFNYFSGKEKVVEYTDKICALQPSGKLNLFGYSLGGNLAFEVTKELESRGRTVAQ
VVIWDSFRITETVEMRQQDFDQFEIELKSHFKDHTGSDNVQQHTLDQAKEYINWCYQTRN
LGEISAPLHFVIAETQASESDKNKELKQSWQHASSTKVSVYQGVGHHAQMLSTEMIAAGN
GDIIRNILSVDTPVLVTQ
>A0A086KI83|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii FOU|TrEMBL
MANAEKLVKLHGLWFRSLWKWAEKIPHEDAVIWLDENGSKAASLTYQKLRREALIIATCL
RQVHCQPGDRAILCYPPSVSFVPAFLGCQICGLTAVPVYPPGSNDRDSDSIQRIVAMVKT
TRPSVVLSSSPLRYFLKEVFPGAAARCVSDIRWIFTDELPDHVEAGSAFELDSLDIKSET
PAFIQFSSGSTGNPKGCVVTHMALLHNIHLNWRMCGAFHPGTEESLYDLPVESYAEFTEK
YQKHLVATWGHRLRSFSWLPVTHDMGLVGMLCVPLFFGCTAFFMSPIDFVRAPHSWLGGM
SKFGCSFTAAPDFAYALAARKVPDDLVLELNFEKILACVNGAEPIRPATIEAFLQKFAPA
GFQPWMMSPAYGLAEHTVGVTGRGSEGRKPMSPKIIEVNNEKVAQGDTVELFKRSGKQEN
EMCTKLIVGCGIPHEDVIVKIVDPRLLQELSEWQVGEVWVSSPSAASGYFGSPVETASTF
NLHLNTADGATRGDRTFLRTGDLGFLGDGELFITGRLKDVVILRGCNYYPQDIEEAVERC
DSVRKGGVMAFSISTTDDAEGLGVAAEIQKGSEKPAKLKLIYADIVRTVNKVLHLPLQRL
WLLRAGSLPKTTSGKPRRSEARRRLLQAERCDDILYSYTRNLSHSGHLPFRPGTFELDME
QKQEDSASTSKSEVNKSLVESLSTAKGARHTDDGFIFTNGQQNLHEAKKDQHGPSDSTLA
EPVSNAILDPITRVTDALLVTADGTSVHKDEEELSLVAECFACVTGVEKSCLRPDTPFLS
LGLDSLTAVELANEIQRRMKQPVEPFELFEFADLRSLALYLRNKKLDHGKDARGRQTKSS
PERSLGIVQVQRPSVFVTGVACALPGSCQTPDKLWEILDAGIDCVGPIPPNRNFCASQNF
AVIGEPRTANASFCVTEGGFLDDVDLFDNSFFGIPDAEAMTMDPQQRLLLMKAVEALHAA
GMATIDSRSAPIATFVGCCSTDWQRMNLGEQIQSFSATSHSASMLSNRLSYTLGLTGASI
TVDTACSSSLTALHCAMQELQHRHVPCHTAVVATVNLLLTTDVTLAFARAGFLSPTYRCK
TFDDAADGFVRSEGVVVFVLQTDVSETPTPNFKNQQEDNEGGQGECGTRIPASGYLCRIL
ASTVVHGGKTGSVTAPSGSSQELLYKQTFACAQVPPRAVDLVETHGTGTRLGDPIEISAL
CNSFAPDMETRKHRLVLGALKTNLGHLEGASGLAGLLKSVLCLNRQRVPPNLHLRKLNRF
IDFRSLPVLLPTKTVPLPASSSETKDAVALVTSLGFGGTYAQVAVQVPSTTGNEMLLRNQ
ETVQWNKKCFDVGKLVSQSNSFQSAVSHNDTKGPCFWEVGWEFLLEFDSITLTLPTLPEQ
APPAKWLVLTSPKAQQSFRKFSVNIFLPGIRMTFACLEELKAPEHLEAILKAETWTAIVS
TYTTETGSCMTDSSDLIGRTLQILQTYGQMASQSAVLPRLLFLTQGCFQVGAAASLLRAS
PYNAGIIGFVRACRLEIESLSGRKAPIYLIDFAANGTLTETLSAVSKLLGMIDIRNVDET
EFAICGKRVFAPRLLPLHLGLEEILPAYDHYMDLTKKADESPAGTAKFPRLVEPANKACR
VRLLALCLDEIFPIEAISPASKAFELGESRPCTLPYGYRNRRQKPSCTKWNERSYSHRRI
RYELPLCWLNRNKANVYFNQKRLGQSTCIFIEVILKLAVRFILPACFTKKMNAAPPSTAR
ENRPLYSALSDLKGLAFLCCAPGPDNASSLCGCSGILLEHGADSQHLTVGNVVCGIMPRP
HCEIVDIPGILLHPSPPSFSCELAASLPPQLALLLWALNQAPPLVTPPAKRVSRVLIVGA
GCGVGLVAATHFQTLGLKTFAVVCTEEQVEALVHYQFPHAAIWCYDRPDLRSALRRELGY
SSIDMVVWALKQEIDSSNNHLLNLLKHGGSFVDLVACHPESRLGWRLDVKYVHCTLDLAA
RPYHAKEFSKNLALSCEILRQKTASQRQQIMHVFFDHAHRLGQHCSLASVQMTEAATPQN
VTSPADLSKQNVSFRPGVNAVEFVSGYSHAGSVVCSLPSPIFFNKASSSNGNCESNASTA
SSSAALGTEASSNVRTGTVLIFDCGSGNTWQHLRQWLSDEGASHIVVVHACAEEGADTLG
VKTLHPSRVNGGQGCSQTLIKEVKCRPHHPEEVVELFKLLKEGLHFPLVRGIFYILGEKL
DSLLANQTTSSVHDMMKTASGAWSIHHALGQLGMEADLDFFIFFSSISALFGSISQSISA
AVHASLDALAYYRRHLGLAATSIQWAPWADGSSATSPQIVRHWLEKGGVSSVRNPLAAVS
AILKNHTAIGAVVACFHADPTIMHEMGETDQECTFLSSGPAANTRDSTSGNVKVRTNPVK
SRVFQNVSPSTDTCGENHKDELLVILTQLVRREVIEIASCYVFFEGNNLSTDESLVDLGL
DSLSAVELRHTLQQRFCVNIEPTFLQANATIDSISALLVTHVATSLTGALPVLPLSCPGL
ASAVDDCALVSLALRLPGRCDSLDAFWASLQSDSGYCRPGASEACDQCFMHRAGSGELPA
ESQSIGTNLDARKGFCWLSNRDEFDSHFFGISFTEALATDPCHRLLLEATYEALCKLNTE
QQSGTSGTPIAVFATSSSTQMRASLPSYTKPASSQNTQDNNGCLAASFLSYHLNLTGLAV
PIDGSDSASLIALDLGREHLRGTDSVCQAVVVAAGSLLPICSHGWPSACTSPTIRRFRGR
DDHAFPDRETYAVPRGEGIVSVVLQRLSVARENGNSPMAILKGISLIRMGRGERPIPSQW
RTADVKLRRKTIVEALKMSRVEPRTVAVLETDGLTGSQAEDAYTVEAMADIFGPRHLAES
CSPLVIGNASLHIGQAREASGLATLAKLVLMLERGYAPPIPRLRRLHPDVKRGILPSGFV
MFPCKKMDLLAFRQHPDHVYGPNEKRDQKEGRPLIGCVSSLGSDKTSGCFIVESSPRRHG
RTSDTRVSLERAVPLAGTKDACSHNYLHVRSTDGSESEIRGDDRAVWLFCDDLWGLQSVG
RGLYCSDPAFAALLEQAERVLGNRIPQPLSCLLYPSTTAEFQKAEDALAFPRIAAFVLFS
LQWALATCLRHQEGEPTAVMGLGVGEIAAAAVAGILSLEDAVELLELLSSETRTCDYRNK
PMPGGNVNSGGLFDRGNSGTGGCGVAQDCKSPWVLCGLNKTPTSESAALEFSVLESRRGS
SSRISSETPTSNTTPHNRDVFQERFSRKPRRATCPSPIIRHAWEKVAHGTPENDEEAELE
CPSSQSRRANCPSPAIQHACEETAHGNHANDGEADLLMDVFRFRPEPSEPLGQVTARIAL
RNATCLFISTVSGRLATDTLIRAAEYWDPLVPKTQRVHRAVETAVQVAKTAKLVCIGCSA
QDGVHLSVGLPSVHPISPSPLRIFCFTGSSPSPQLLAPCESASGSSPRVAVVEHHGADSN
LGGGAPWWKHLLFRLPQLEGFPSGCSASTRLLADRLVADVPTPDNHMINNPQTAAVQGAG
ETLGTLREGSSGEGEDGEKGYRSESVNTQHPVYKVYRRCSEPELHESELSLLCSDTVCQP
SLEKTVELFIGTGLEQQGKLSTVSSSWLVFSDIVAPSPISLYSTLAFQNEDGEQRFCTLN
VASQVATVYAEKVKTQVCSIIIECKRGFKPPREIARCHFVKNQTAVGKHEPAVSSLSRIR
WLPATKLSEGWLRTRRPHVWPCKIKVTKAACPLPTRRVDLQEIYWGKRHILCRFRMPRNP
PRDGVEKSTQLIAILARLVTVSVGVAATCVLHETETSGRYSHSHPGPQVEDDQKTHMDAL
WVCPYVPFSECWCVIRHRRNGSSIKEGKGRDWETCDVEIFSENGTAVAVVLGFGIQSHAL
SMRMMEGRGNDGDSSVSTTVCVA
>D3DCV0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. EUN1f|TrEMBL
MPISTPADSTRSATGGRSEESHAQRDAGSTAGPAGGDERLRAYLRRALTELQQSQLRLRE
VEDAAQEPIAIVGMACRLPGGVDSPAGLWDVVAGGVDAVSGFPVDRGWDLDGLFAAAAAA
AEDAAVAVAGDAAAEAGAGGPAGSTAARSGGFLQDVAGFDADLFGISPREALAMDPQHRL
LLEVSWEVLERAGLDPRALRGEPVGVFTGLMFHDYSHHVERLPTGLEGYFGIGNSGSAAS
GRVSYVFGFEGPALTVDTACSSSLVALHLAARSLRSGESSLALAGGAAVMTTPEVLVDFS
RQGALATDGRCKAYADGADGTGLSEGVAILLLERLSDARRHGHRVLAVVRGSAVNQDGAS
NGFTAPNGPSQERVIRAALASAGLTAADVDVVEGHGTGTRLGDPIEAQAVLATYGQGREN
GPPLLLGSVKSNLGHTQAAAGAAGVIKMVEALRHGIVPKTLHAARPSAQVDWSAGAVEVV
AEQVPWPATGRPRRAAVSSFGISGTNAHVILEAVPDEATVQPPSPLPAPAPVPLPVSANS
SAAVQAQVEAVQALVAEGVAAADLGVSLDLRSRFAHRAVVLGEDVVLPRPGLADGGRTAW
VFTGQGSQWREMGLGLAAAFPEVAETFDAVGAATGTDLPALLASAGIDGTGLAQLGIFAV
QVGLARVLDRAGLRPGAVWGHSVGLIAAAQVAGVFSLADAARLVAARGALMAALPAGGGM
LSAAVDVPEAREVLALLPERARALVSVAVVNGPRSLVFSGDAVALREVESLLADRAARTR
WLRVSHAFHSPLMDPMLDAFAGVVAGLTIAAPVLAGLPERVTDPDFWVRHVRDQVDLPAA
VRELSGLGVTRWVEVGPDAVLRPLVEQNLDHLHSTDAGPAHLDGPAHLDGPAHLGGHTHL
VTSTMRRGTPETATIAAALADLWVGGQDVDWSSFRAGGTRTDRLPTYPFQHERYWIQPAA
GGPANVAAAGLDAAGHPLLGAALDLAGAPHEVLTGRAAVPEQPWLADHAVAGVVLAPGAV
LVELALHAGARAGYPDLLDLAIDNPLALPRAGERRLQVHLGEADGSGRRPVSVYSRGGQD
GAEG
>A0A0L6JGW4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933|TrEMBL
MENKLLNFKSIKIGDMDKDYLSRINDISKRDVAVIGVSGRFGCTNSVDEFWEALKTGKDL
IGEFGGLRKEDSDAYLKFWMQTGLLAMNPQYNVGAFLEEIDKFDCGFFNISPKEANGMDP
NQRIFLETAWEAIEDAGYGGQRIKGSRTGVYVGFSNDSGDEYKRYIQMLAPNQTALNDPG
NIKSIIGSRIAYLLDLKGPSMMIDTACSSSLIAVHLACQGIRNGDCDMAIAGGIKVFITP
LKTIHENDRIGIESSDGRAKTFDDSSDGTGVGEGVGAVLLKPLNKAVEDGDHIYAVVKGT
AINQDGASVGLTAPNAAAQEDVILRAWKDSGIDPQTISYIEAHGTGTKLGDPIEIKGIEK
AFKCYTDKRQFCAITSVKTNIGHLDNAAGIAGFIKAVMALKHAQLPPSLHFAKPNRKISF
EDSSVYINDRLVQWDTKPFPKRCGISSFGLSGTNCHVVLEEAPEIKNDTWSIENKIYVLL
ISAKSETSLKESIRRYAELLKSGKSPELAELCYTANTGRGHYSYRLAVITKDKLELQEKL
YKLSDMHSGSNDEGVYYGIHKLVSSRREVKEAYEYTDEEIKELSILAENMVETFLKSGKT
SMGALEKVCSLYVKGAEINWQDFYRDEKRKKVRLPVYPFERTRCWIDLPKSENLMLPHHF
QNLYYSAVWRKRKPQQAKNEAKEGSTIVLKGVGEKIEEIVKRLRQCRKDIIEVKLGEGFQ
SLNDGNFIIDGSLESFKRLLSKLKDRNISQVIHLCTAQGSVEIKDVIEIDESQKKGVYNL
LYLSQAISSREIKEPIDLVVISEKVYEITGMEQMIYPQNATLFGLGKVVRLENPMLKCRC
IDIDRETGIDTILIEINYPSDEYLTAYRNGDRYTQEIGHADLSRLDDDEIEVKNDGVYII
TGGTGRLGLKIAQWLASQNKVNIALLNRTHFPDRNVWERIIVEGKDPELCQRIEAIQKIE
STGTAITLCSTDVTEITELNSTLSKLRECYGKINGIIHCAGIGVGSKGILLKDEQRETFE
NILAPKVYGTWLLENLTKDDNPDFLILFSSAITITGGVGAGSYTTANTYLDSFVLKAKKY
FKKVLSINWTTWESVLRFAGVKIDKDRLIFKIIPDDTALKAFDIVVHKKINNVIIGEMNI
GSSIFDIKPYMPFTLSQDTQSEIKQNRTQIKLDSFSDALPEVTLTGKAENESYTEMEDRI
ARVWGKVLGIGEINIYDSFFDLGGHSVLAVKLEVEMGKAGMPVEGADIYKYQTIKDMASY
LGTKEACPNVQKCILDNIEPFNELYYKSCFYNALFPVVRHFNKSLIPVLINDMILYCMNR
DKENPDIEYRAVKNVESVLDEQGITVVKKHQSLDVIGDICKSVSGGRPVILWVDCFYASI
RPDTYEKVHWAHTWLVYGYDDNKREFHILEHKHRDSLTYEKRAISFQGVVDSYNGFINFF
QPDKNTSTYYEFYPDSTSSEDDLGIYLRIFKKNMLDYKKTIAEGLQEFASFIDFFKLTVA
DREILAKYSIEDCIQGINNIINAKLVERFRAERLISDNSGILEILDKIINYWNSVRSVLA
KVLYSNTYKDDDFDYICDQLELILRDELNLQKILVTSISY
>A0A0N1GQC1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MSESVRTPNGSERTPCGLDTTPRRAIAVIGLACRLPGAPTPDALWRLLRAGDSAIRPTPA
ERLGVGAGTADASDSPSGDGAPRWGGFLDDVDLFDAGFFGVSPREADAMDPQQRLVLELA
WEALEDSRIVPGRLADTSTGVFIGAAHDDYATLLHALGPENVTHQSFTGTHRALIANRLS
YLLGLRGPSITLDSAQSSSLVALHLACESLRSGDSDLALVGGVNLQLAPESSLYPHRFGA
LSPDGHCYTFDARANGYVRGEGGGAVVLKPLDRALADGDPVRAVIRGSAVNNDGGGDTLT
APDPRAQEDVIRRALRNAGAAPYDIQYVELHGTGTPVGDPVEATALGAALGAGRNADEPL
RVGSVKTNVGHLEGAAGIAGLLKTVLALQHRELPPSLNYAHPNPDISFDALRLRVQDGPG
PWPRPDVPLMAGVSAFGMGGTNAHVVLEEAPGVAPGSAAETEVGDGTGAVFAAGGGVVPW
VVSGRGAEGVAGQAGRLAAFAESAGDDGVRPVDVAWSLAGSRTAFDGRAVVVGSGVAELG
AELGVLASDGVTGAGVVRGVVAGGADRVVFVFPGQGAQWVGMGRELWDSSPVFAASMEAC
ERALSLFVDWSLSDVVCGGGELVDVDVVQPVSWAVMVSLAALWRASGVEPSVVVGHSQGE
IAAAVVAGGLSLEDGARVVALRSKAIRAIAGRGGMVSIALPLAGVEELLAGWAGRVDVAA
VNGPGSVVVAGDADALDSLVAHCEAAEVRARRVPVDYASHTWHVESIEGELAEALAAVAP
RSGSVPFFSTAEAELVDTARLDGGYWYRNLRQRVRFAEAVESLAGQGYAAFVEVSSHPVL
GMAVQEAAPDAVVVGSLRRDQGGAERFLTSLAEAWVRGVAVDWTAVLSGRGARTISLPTY
AFQRRRYWLQGGESGARRRTLPAEVVGEADELASTLTAAPSALSVLPVGRDDLEQRVRAH
AAVVLGHGAAGDVEVALTFKALGFDSATSVELRNRLVTETGLSLPASVLFDHPTPRALAR
HLRGLLHGDTEHTPQLPVSARPDTSEDPVAIVGMGCRLPGGIHTPEALWELLTTGGDTVS
AFPADRGWDLDGLYHPDPEHHGTTYARAGSFLYDAAEFDPGFFGISPREAEAMDPQQRLL
LETSWEALERAGIDPETLREGDGGVFVGLMPQEYGPGLSHAPESVDGYLLTGTSCSVASG
RIAYLLGLRGQAVTVDTACSSSLVALHLAVQALRSGECSFALAGGASVMAEPGIFVEFSR
QRGLAPDGRCKPFAAGADGTGWGEGVGVLLLERLSEARRKGHPVLAVIRGSAINQDGASN
GLTAPNGPAQERVIRAALTDARLTPDLVDAVEAHGTGTTLGDPIEAQALLATYGQGRAAE
RPLWLGSLKSNIGHTQAAAGVGGVMKMVLALQHGLLPRTLNVDQPTSHVDWSAGAVSLLT
EAVEWPSGEGRVRRAGVSSFGISGTNAHVVLEEAPLVSRLDEDGGSGSGSDSGSGSGLGS
DSGLGSVLGAGGVVPWVVSGRGAEALAGQAGLLVSFVESAGEGVRPVDVAWSLARSRTAF
GDRAVVLGRERAELALGVGELAGGGEVMSSSVVRGRAASASGDVVFVFPGQGAQWVGMGR
ELWESSPVFAASMEACGRALSLFVDWSLSDVVCGGGELVDVDVVQPVSWAVMVSLAALWR
GAGGGPSVGGGGSEGGGG
>A0A0N1G6S9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
TWLLLTPTTEHATATATITAVTTALTTHGATVRTLAVPPGTDRTHLTTHLTSAANGDAQP
VGVLSLLALDESPYAPGSPLDNGLVLTTALVQALGDAGVTAPLWLGTCGAVSTGRADRLA
APVQAQAWGLGRIVALEYPQRFGGLVDLPRELDERAMARLVTALSGADDEDQLAVRGSGL
FARRLVRATLPEPAPADWQLRGTVLVTGGTGGVGAQAARRLAADGAEHLLLVSRSGPDAP
GAEQLQHDISQLGARVTLAACDVADRDQLAALLAAIPAELPLTAVVHAAGVLDDGVLDGL
TPERAETVLRPKTAAALHLHELTRDLELDAFVLFSSLAGTLGGPGQGSYAAANAFLDALA
RQRHADGLPATSVAWGAWGGGGLASGATGERLARSGMPAMEPELALTALQQAVTSGEPVL
AVADVRWETYAFAHSDGAARVLADLPEVRTALAARTTPATTGSSGDGNALIVRLAALPHD
EQRRELLALVRTLAAAALGFPGVDEVDEDRAFRDLGFDSLTAVALRNTIAETTGLRLPVT
LVFDHPTATALAAKLHTDLFGATATAVERTAVEPGAAADDDPVVIVSMSCRYPGGVDGPE
ALWRLLAQGGDAVAPFPDDRGWDLAGAYDPDPDKPGTFYARGGGFLYDAHHFDPEFFGMS
PREALAVDPQQRLLLETSWETFERAGIDPAGVRGSRTGVFVGSNYHDYGSRVQRAPKDFE
GYLATGSAGSVASGRISYTFGLEGPAVTVDTACSSSLVALHMAAQALRTGECTMALAGGV
TVISSLDTFIEFSRQRALSEDGRCKAFADDADGAGWAEGVGVLLLERLSDARRNGHPVLA
VLAGSAVNQDGASNGLTAPSGPAQQRVIRQALAAAGLTPADVDAVEAHGTGTKLGDPIEA
QALMATYGQDRPAGRPLLLGALKSNIGHTQAAAGVGGVIKMVLALRHGQLPSTLHADRPS
TQIDWSAGAVSLLTEPVDWPSDAERVRRAGVSAFGISGTNAHVIVQEPPAEVEAETETAR
PMATPVPPTGVTAPAPLPGEAVVVPWTLSGRTPDALRAQAARLLAHLDDHATAPEADAAT
SLDIAHELALGRAVFDHRATAVGRDRDELVAAVRALAEGREAPGLVRGVRRRRGRTAFLF
SGQGSQRPGMGRELYAAQPVFADALDAVCAELDRELERPLRDVLFAPDGTPDAALLDRTA
YTQAALFALEVAQFRLLEHWGVRPDLVVGHSVGELAAAHVAGVLDLADACRLVAARGRLM
EQLPDGGAMLAVQAGEAEVAEALRAYEGRVSIAAVNGPAAVVVSGDADAVEELAEIWRES
GLRTKRLTVSHAFHSPRMEPMLTPFAAVAHTITYAAPAVPVVLDLTGELADADRPLDADY
WVRHVRGTVRWADAVATLNGQGVTAYVELGPDGVLTAMTRDSLTAEVPEAAPETDAVVIP
LLRRDRPEETALTTALATLHTHGVSPDWTAYFGGRPVRRTELPTYAFQHSRYWLDADPGL
PDLAAAGLAAGEHPLLAAGTALAGGDGYLLTGRLSLSAHPWLADHAVSGTAILPGTAFLE
LALLAADRVGCAAVDELTLEAPLVLPEQGAVHLQVTVGAAGEEGVRGVTVHSRPDDAPDD
EPWTRHAVGQLTPETTPVDDSPLTVWPPEGAEPVAVDGVYDRFAAGGFAYGPAFQGLAAA
WKHGEDVYAEVQLPTEAGSDADRYGLHPALLDAALQTVGLTAAAAGPALMPFSWTGVRLH
ATGADALRVHLAPAGPDTVALRVTDPAGGAVATVTGLTLRPLPAGQLGDTRTAARHLHEL
EWITPAPTSARPTATGWAVLNGAADPGITAALTAAGLTATDHPDVTDLARAITTGDTTTP
AVVLAAVPGPEAAVLGREAAVLGPEAVVPGPEEAADTAELAAAVRRTTAHVLRLLQDWLA
EDTLHGTRLVLVTRHAVTAYDGDRAPDPVAAAVWGLVRTAQSENPERIVLLDWDGAQESH
RALPAAAGHEEPQLALRKGETRVPRLVRTRLTQSADDTGRTLLDPDGTVLVTGATGALGG
LIARHLVTRHGARHLLLVGRRGPDAPGARELLDDLAELGARTELVACDASDRDALAALLA
TVPADRPLTAVVHTAGVLDDGVIGSLTPERLDTVFAAKADTALHLHELTRDSDLRAFVLY
SSLAGIFGGAGQGNYAAANAFLDALARHRRAQGLPAQSLAWGLWEQRSAMTGKLDDADLL
RMARGGVVPMPSEQALDLFDAAVAADREVLIPARFDTAGLRTPDGEVPALLRSLVKPAAR
RRTGTAADGDAPAPAEQLRHRLAELDTEARLTVLLDVVRDQAAAVLGYADSDAVDPERGF
LEMGFDSLTAVELRNRLTAATGLRLPATLLFDYPTPVGLARHLRTETAPAAATAVQPMLA
ELDRLERALEEVAGDETVRTTLADRLRGLLTRLDVAAAPAEHSGVPGSGSGSGDAVATAV
AVEEQLDAASDDDLFDFIDQQFGTQ
>W4A549|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Rhodococcus rhodochrous ATCC 21198|TrEMBL
MADDAKLLDYLKRVTAELYQAREKLREVEGVSREPIAVVGMGCRFPGGVRSPQDLWRLVE
SGSETVSGFPTDRGWEAADLYDPTGRQAGRTYTVQGSFLDDAAGFDPEVFGISPREALAM
DPQQRLLLETSWETFEHAGIDPRSVHGRQIGVFTGLSGIDYSARAGGAPPEELAGYFITG
TAMSVASGRVAYSFGLNGPAITVDTACSSSLVSVHLAMQALRNGECELALAGGATVMSTP
AVFVEFSRQRGLAHDGRCKAFSAAADGTAWGEGAAILALERLSDAERNDRRILAVVRGSA
VNQDGASNGLTAPNKQAQERVIRQALTDAGLGPADVDAVEAHGTGTTLGDPIEASALLAG
YGRDRPPDRPLWLGSVKSNLGHTQAAAGVAGVIKMIMAMRHGVLPRTLHVDRPTPHVDWS
AGSVSLLTENREWPATDRPRRAAVSSFGISGTNAHVVLERPAPPPDAAPTDGIDGSDDVV
AWFVSGHTEPALRAQAHRLGDYVADHPELTPAQVAGPLLTSRATFDHRAAVLGTDRTALL
SGLDALGRGAPDPGVITGVAVEAGDRPVFVFPGQGAQWVGMATELLESSPVFADSLRECA
DALAPHTGFALLDVLRDRDPAALDRADVVQPALFAVMVGLARLWHAHGVEPAAVVGHSQG
EIAAAHVAGALTLPDAALVVAARSRVITESARRGGGMASVGLPADAVRQQIEPWAGTVEV
AAINGPAATVVSGPGDALEVLVARWQADGVQARRITVDYASHCADVSVLRRPILDALAPI
TPQRSRIPFYSTVSGDMMDGTALDADYWYRNLRRPVRFEDATRSLARDGYRLFVESGSHP
VLTVPLQETLDAAGIAGRALGTLRRDRAGLRQFTTALAEAHVSGAHIEWDRVGWARRAGH
RQWVDLPTYAFQHRRYWLDGGAPQRDAAAAGMDAGDHPMLAASVELGDGRGAVFTGVLSP
HRLPWLNEHAVDGTVVLPGTAFVELALHAGHRAGCSRLAELTLETPAPVPTGGELAVQVA
VLTADDAGHCTVSVHSRPADAPAQTPWTRHAVGALTGAVHTAQVPIRQWPPADATPIDVS
GLYDALDETGYGYGTVFRGLRAAWRRGDDLYGEVRLGGEDPAAAVAGYGIHPAVFDAALH
LIAFAAAEAGARDLQLPFAWDDVQLHAVGATALRVHIAPAGPERYRVAAYDTAGKPVLTA
RSLALRPFAGPRAPAAATGTGLYRVEWIPVEAGAAPTADLAALGEALTGGDPAGRTLLLA
GEPDDESDVPTRAHAAAEAALRAVQAWLADERLAETRLLVTTRRAVAVTDDEPIDVGAAP
VWGLIGAVQNEHPDRITLVDLDRPPGDLPDPTVLSAALACDEPQLAVRAGTLLAPVLAAV
PTATDAAADPVPFGPDGTVVVTGGTGTIGRLVARHLVRRYGVRRLVLTGRHAVRAERATD
LRAEFAEAGAEIRAVTCDVADRAAVAALLDAVPDLSGVVHAAGVLDDATAATLTPDQLHA
VLRPKVDGAWHLHELTRDRGLAAFVLFSSAAGVLGGAGQANYAAANVFLDALAQHRRAEG
LPGLSLAWGLWDRPSGMTSHLNAADLDRLQRTGIDTLTPEAGLALFDAALAANRPLTVPI
RLSAPARRSDGEALPPILRRVLGTSRRRAAAAPSAPGLADELRALDPAERHARVLEIVTT
HVAAVLGHDGKEAIDPDRAFKQLGFDSLTAVQLRNQLTTATGVRLAATVVFDHPTADALA
REIAARLLGPEDAPQPTRTARRRHDDDPIAIVGMACRYPGQVSCPDELWRLVRDGRDAVG
AYPDNRGWNLDEVYHPDPERSGSTYMRAGGFLYDADRFDAAFFGISPREAVAMDPQHRLL
LESAWEALEYAGIPPNSPGLTDTGVYVGMMGGDYGFHLMTRRSTDAEGYLMTGTSNSVAS
GRIAYSLGFTGPAVTVDTACSSSLVALHLAARALRDGECTLALAGGATVMATPGVLIEFS
RQRGLAPDGRCKPFSDRADGTGLSEGAGMVVLERLSDAQRHGHRVLALIRGSAVNQDGAS
NGLTAPNGPSQERVIRQALADAALDPADIDAVEAHGTGTTLGDPIEAQALLATYGQQRDG
RPLWLGSVKSNIGHSQAAAGVAGVIKMVMAMRHGVLPPSLHSDAPTRHVDWTSGEVALLA
EAVAWPQTGRPRRAGVSSFGISGTNAHMILEQPPDVAAPAAPPRSASPLVWVLSAKTDEA
LRAQAARLTDVLDRDALDTGAPPDPADLAYSLATTRSGFTHRAAVTGETLADLRDGLARL
AEGRAGGNAVAGTSARGRTAFMFTGQGAQRIGMGRGLYDTYPVFARALDETCAALDEHVD
TPIRQVIWGDADEAAARLDRTEYTQPALFAVEVALYRLLREWGLTPDYLIGHSIGELTAA
HVAGVFSLPDAAALVAARGRLMQATAPGAMIAVRARPEDVRSRIDGRVDLAAVNGAESVV
LAGAAADVHAVAAELSTAGIAVTTLQVERAFHSALMDPVLDEFTTVVSRPAAQPPTIPVV
STLTGRVATAEELTSPQYWRRHIRRAVRFHDGMRTLAELGVSRCVEIGPGAALAAHAAEV
VPHPIATLPGRGDDARGFVEAVAAASVQGLAIDWDRVLPGRRRVDLPTYAFRRRSFWPSA
PARTSGDPTELGLSPADHPLLGAAVTLDDDTTVFTGALSRHRDSSLAAPQPGDPPTDAPQ
TLVPAVLVELTLHAAHHVGCDRIAALTLHHALGLPAAGSLPIRVLVSPAGEDGARTVTVS
SNMGPADGPWVRNASATVDDVLAAQPDRLPGDTTTEVRLDDGVDPSGFGIHPQLLQAALD
SVFGPDDWPLTWSGTRLHRTGAQAVSVRCATGEDGRYRVDATDADGAPVLTVEALHVVPR
TGDGDGAGPSGARRLHRLAWTRIDDLPSEPPPGPMVVLGAADLESSLSRCPDAAALRTAR
AATPDDGRPWTVLVGCGTDGDPGPEATHHLCARTLRLLQDWLDDAEFVDSVLVVVTRNAT
ATGEEGEGVDIDLAAAAVWGLVGSAQNENPGRFVLLDLDRETDVDTAITSALASGEPQVA
VRGRAVLVPRLRRIPAVQRSGPLFDPRGTVLVTGGTGTVGGSVARHLVSTHGARHLVLTS
RRGPDADGSDRLRRELRDAGAEVRIVACDTADAAALAGLLARIPAEHPLTAVIHAAGVLD
DATLTSLTPDRLDAVLRPKVDAAWHLHRLTAGVHAFVLFSSLAGVLGAPGQGNYAAANRF
LDALAQHRRAHGRPAVSIAWGMWAPPSAMTGRLGAVDLARARRSGLVPMSEADGLDLFDS
ALASDLSAVVGARFEHLGAAATSVPAPLRGLVRQARPRAAGSGSALSGPNGSGPLEWAQR
LTDRSVPEQRHLVLELVRAGAAAVLGHDASDSVDPDQAFKELGFDSLAAVALRNHLGAAT
GLRLPPTVVFDHPSPRAVAEFLRAELVPDPVSVAVAGIDRLQAVVADLGADDEVRAAVAQ
RLEALLADLAGAERGRADTVDRIHAATGDEILDIIDRGL
>A0A6C0QC60|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. S4.7|TrEMBL
MSISTEDKLRDYLKRVTADLRRTRQRLDAAVSGEQEPIAIVGVACRFPGGVASPEDLWRV
LADGVDTVSTFPTDRGWDLERAVGESETLRPEGREPQGAFLDDIAGFDAEFFNISPREAL
AMDPQQRVILEIAWEAVEHARIEPRSLRGGRTGVFIGATHQDYGPRLSEPAEGVQGHLMT
GSLPSVISGRVAFTLGLEGPAVTVDTACSSSLTALHLACQSLRQSECDLALAGGVTLMAT
PGMLVDFDYQGGLAPDGRCKAFSDGADGTGLAEGAGVVLVERLSDAVRNGHEILAVVRGS
AVNQDGASNGLSAPNGPSQQRVIRQALANAGLSVADVDAVEAHGTGTTLGDPIEAQALLA
TYGKDRPENAPLWLGSLKSNLGHTQAAAGVAGVIKMVLAMREGVLPRTLHADEPSSHIDW
SSETVRLLGENTPWPEGEGRPRRAGVSAFGISGTNAHVILEQAPAAEPVETTETDDASGS
SSGVVVWPVSGHTSDALAAQASRLHAHLSAHPEVTPEQVAHALTTTRTALSHRGAVVAAD
RGELMEGLAALGEGAPSAHVVSGVTRPQGKTVFVFPGQGAQWPLMTADLLTTEPVYAQSI
DACAKALAPYVDWSLRDVLTDPAGGLLERVDVVQPALFAVMVSLARLWEHHGTSADAVIG
HSQGEIAAAHIAGALSLEDAAKIVALRSKALTSLTGRGTMASVTLPHEQVTEQIAGYDSL
SVAVINSPTHTVISGTTEDIYTYLDHCTTNGVQTRLLPVDYASHSPHVEALEEHLLTVLA
DITPRAASIPFHSTTHPAQTPTDTTTLNSTYWYDNLRQPVHFHTALTHLNNTGHTTYIET
SPHPTLTTPINQTNENPETXNGNDTPLTVTGTLRRHQHGPTQFRLAQATLHTHNTPTTWP
TPTTQPTTLPTYAFQHQHYWLNTPTGGGSDPTTLGLQHTNHPLLGAAVQLADSTTHATVF
TGTLNQRTHPWLSDHTVTGITVLPATAYVDLALHAGHHTNHPRLTELEMHKPLVIPEQAT
LQLQVMTAPLPDSDDLRVTVHVRQELDAAWVLHATGTLSAAVPAAEADLTAWPPADARPV
APADVYTELVARGNEYGPAFQGLTAAWRDGDDLYAEIELDPDTDVTGYGIHPALLDAALH
TLGIDTSPSDANEPQLPALWRDISLYATGATTLRVHLGRSGPGSARVLVADAVGQPVAKI
ESVALRPVETAQLAAAGTSTHNRLFAVEWTATALASDADSNPGDHQSWTILTAGTPATAP
PESITHLELDPADPDLPLPQQVHHAAAQTLQHLQDWLTNPANTDRHLIVLTHHAVTTHPG
ENITDLTHAPLWGLIRSAQNEHPHRITLIDTDNHPDSNKHLPGAVHAATTAGEPQLALRN
GDTLVPRLARHTPTPGNTLTLNPHGTTLITGGTGTLGALTARHLVTTHGARHLLLTSRTG
PDAEGAHELHQELTALGADIRITACDAADRQQLTALLDTIPAEHPLTAVIHTAGVLDDAT
IDNLTPQQLTTVLAPKVDAAWNLHQLTADHNLDAFILFSSAAATLGATGQANYATANTFL
DALAHHRHHNGQPTTSLAWGYWAQPSGMTAHMTTNDINRLTRTGITPLTTQQALTLLDTA
TTHPHLIPTAINTTTIDPDTASPVLRKLIRPRRTTAARSTVTMGGFAEELRALPESEQRE
RLVTLVVSHAAVALGHSDGTSLLPHRPFRELGIGSLTAVELRNSLARAIGSALPTTVVFD
YPTPQELADHLRGLLLQTTAAPRRSVAAVRTAEDEPIAIVGMACRFPGDVRSPEDLWQLL
RDERDAVGDFPTNRGWDVERLYDTDPDHPGTSYVRHGAFLHDAAEFDADLFHMSPREALA
TDPQQRLLLETAWEAFERAGIDPTSLRGTGTGVFTGVVNHDYLSRLSSVPDEFEGYRRIG
TAPSVASGRVSYAFGLEGPAVTVDTACSSSLVALHLACQSLRSGESTIALAGGVSLMASP
DLFVEFSRQRGLAPDGRCKPFAAGADGTGWSEGVGLLLVERLSDAVRNGHQVLAVVKGSA
VNQDGASNGLTAPNGPSQERVIRQALANSGLSGADVDAVEAHGTGTMLGDPIEAQALLAT
YGQDRSDGTPLWLGAVKSNIGHTQAAAGVAGIIKMVMAMREGVLPRTLHVDEPTPHVDWS
AGAVELLTENTPWTVGEDRPRRAGVSSFGISGTNVHVVLEQAPAIAPVEGETEPSESGSS
GVVVWPVSGHTADALRAQALRLHAWLEDHPDADLPAVADALAGTRATLDHRAVVFGTGRG
QLLDALSGIAAGTPTPHGVTGRYQAGKLAVLFTGQGSQYPGMGHGLYTTHPVFRDALDEA
CAALDPHLPVPLLSVMFAGPGTPEADLLHHTTHTQPALFALETALYRLVESYGVRPDALA
GHSIGELTAAHAAGVFTLTDAAVLVATRARLMGELPAGQGTMLTLHTTPDHITPLLDGTT
LEIAARNSPTNTVVSGTVSDIETLTARAAEAGIRTRALNVSHAFHSAHMDPVLDTFRTTL
STLNPQPPTLPVISNRTGQPLTPEQALSPDYWTEQLRHSVNYTDITHHLDTTGTTTYLEL
GPDTTLTTLTTQTLPDATAIGTLHPKHPHHHTLHTALATLHTHHTPLTWPTTTHPTHHHP
TLPTYAFQHHHYWLNDTPAIRDLTSAGLATTDHPLLGATVDLAQGDSAVFTSSLSLRTHP
WLADHTIANRALLPGTAFVDLALHAGLHLGCDRLTDLTLATPLAVPEQGSVQLQVTVAQE
GASGERIVTIHSRPEGFESPWTAHATGLLAPAEERSDAPATGLEAWPPHGAATVDVGALY
ADFAAQGYAYGPAFQGLRAAWQADGHVYAEVELASDVDVNGFGVHPALLDAALHTLALDA
RTSGHSGDEVKLPYSWSGIRLYATGATAARVRLTPTSETTATVTLSDATGQPLLAIDVLT
LRSVDAKQLNTSAGSDRDGHLFVLDWTEMSPVEETTETVVSDLRIFAAGPDTGEFNAVGS
NTSVFAALPPRDLELPLPERVFTATAHTLRVVRDWLSDDSASGAPLVVVTRGAVSVTPEN
DIDLVHAPLWGLLRSAQSEHPHRFLLVDVDDDPASLAALPSAVTTAVARQEPQLALRAGA
TLVPRLVRHDAGAPTQESATASRTASATTFRPDGTVLITGGTGAFGARIARHLVSAHGVR
HLLLVSRSGPDTEPATALRQELTGLGAEVVVAACDAADRDGLAALVSAIPADRPLSAVVH
AAGVLDDGTLAQLTPEQLRGVQRPKADAAWHLHELTRDLELDAFILVSAGAATLGTAGQG
NYAAANTFLDALAAHRRHHGLPGLSLAWGFLAQDAGMTGHLDERDRARLARNGAVPLSVE
RALELFDAALAQAAPAHLLPLAMDSAQPLLHGLVRKRRAVTMAVAGRPSGSASGAGGQGL
AELPPEARLTRLTELVTTLVAAVLGHVDSQQLDPGRTFSELGFDSLTAVELRNQLGAATG
LQLSSTLVFDYPTQQALAAYLSTRFAETATVRPSAHTQLQDTEPIAVVGMACRYPGGVTT
PDDLWELLQGGRDAISDFPDNRGWDLDSLYDPVPGTRGSSYVREGGFLHDAGQFDPSLFG
MSPQEALATDPQQRLLLETAWETFERAGIDPRSLRGSQTGVFAGVMYSDYAARLLPDTPE
GFEGQIGNGSAPSIASGRVSYAFGLEGPAVTVDTACSSSLVALHLACQSLRSGESSLALA
GGVTVMASPSMFVEFSQQRGLAPDGRCKPFAAGADGTGWSEGVGLLLVERLSDAVRNGHE
VLAVVKGSAVNQDGASNGLTAPNGPSQERVIRQALANSGLSAADVQAVEAHGTGTTLGDP
IEAQAILATYGEGRPEDAPLWLGSLKSNIGHTQAAAGVGGVIKMVMAMREGVLPRTLHVD
EPTPHVDWSAGAVELLRENTPWTVGEDRPRRAGVSSFGISGTNAHVVLEQAPAVEPVDAA
TDLEETAGVVVWPVSGHTADALRAQALRLHAWLEDHPDADLPAVADALGHTRATLDHRAV
VFGTGRGQLLDALAGIAAGTPTPHGVTGRYQAGKLAVLFTGQGSQYPGMGHGLYTTHPAF
RDALDEACAALDPHLPVPLLSVMFAGPGTPEADLLHHTTHTQPALFALETALYRLVESYG
VRPDALAGHSIGELTAAHAAGVFTLADAAVLVATRARLMGELPAGQGTMLTLHTTPDHIT
PLLEGTTLEIAARNSPTNTVVSGTVSDIETLTARAAEAGIRTRALNVSHAFHSAHMDPVL
DTFRTTLSTLNPQAPALPVISNRTGQPLTPEQAVSPDYWTEQLRHSVNYTDITHHLDTTG
TTTYLELGPDTTLTTLTTQTLPDATAIGTLHPKHPHHHTLHTALATLHTHHTPLTWPTTT
HPTHHHPTLPTYAFQHHHYWLNAPTNNSGSGQVGSAEEARFWQAIEQGDLDALATALRLP
GDADSAEATMTALSPVLPMLSSWRKQHAERSAVSNSRYQLSWTPVNTPSSAALSGRWLVV
SAEDAGEAGEHGEAGSSADWTAWCTAALRRAGAEVVELKTDGPSVDRADFVKALGNLPGD
EHPPAGVLSLLALTGTDATGYVPLSATAALIQALGDAGLQAPMWSLTSGAVSTGVSAPVT
HPAQAHVWGLGRVAAAEHPDRWGGLVDVVGKLDERSGGLLAATLAGNGGEDQVAIRPGGV
FGCRLRTASGGRPPRRDWRPAGTVLVTGGTGALGAHVARWLAGKGAAHLLLTSRRGESAP
GAGQLRAELAELGATVTIAACDVADRGELASVLAAVPTEQPLTAVVHTAGLLDDGVLDAL
TPERLKRVLRPKTDAVLNLHELTKDLDLSAFVLFSSIAGVLGSMGQANYAAANAHLDAFS
EYRRAAGLPTTSIAWGPWSGDGMAADEAVDRNIRDTGVRPLAPDVAIAALQEALDRDETR
LVVADIDWQLVAASAADAARRDPLLGEFPEVRAVWQAADQVAADGALAATALRDKLQGAG
SKAEREQVVLELVQSRLATVLGHGSADLVEGDKAFREVGLDSLGSIKLRNAVNAATGLNV
SATLLYDYPTPLALSQYLLTEITEEDTVTEATLLAELERLDDALRSLALADSGRRRVAGR
LQVLLSKWGDGPDQTDEDSSHQDLDAVTAEELFDLISDEFGKS
>G0AUI8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Shewanella baltica BA175|TrEMBL
MSHTPSVPNSATESKKDKRLNKRLKDMPVAIVGMASIFANSRYLNKFWDLISEKIDAITD
IPDTHWRAEDYYDADKSKADKSYCKRGGFLPEVDFNPMEFGLPPNILELTDTSQLLSLIV
AKEVLADANLPTDYDRDRIGITLGVGGGQKISQSLNSRLQYPVLKKVFKSSGLSDEDSEM
LIKKFQDQYIHWEENSFPGSLGNVIAGRIANRFDFGGMNCVVDAACAGSLAAMRMALTEL
TEGRSDMMITGGVCTDNSPSMYMSFSKTPAFTTNETIQPFDIDSKGMMIGEGIGMVALKR
LEDAKRDGDRIYAVIKGVGASSDGKFKSIYAPRPEGQAKALERAYDDAGFAPHSIGLVEA
HGTGTAAGDVAEFNGLKSVFAQGNDTNQHIALGSVKSQVGHTKSTAGTAGVIKAALALHH
KVLPATINVSQPNPKLNIESSPFYLNTETRPWFQRADATPRRAGVSSFGFGGTNFHLVLE
EYKPEHSRDEQYRQRSVPQTLLFAAANKAALLSELKAALSQSVNTNANKSSAASLNAIAQ
QYPLRTLASTDARLGFVAKDIAQLQAQLNQSIAHLETNAIEVWQLPSGISYRSHALVAQN
ESKKVAALFAGQGSQYLNMGRELACHFPEMRQQVMASDKVFAHHGQTPLSNILYPIPAFD
ADAVKAQEAALTNTLFAQSAIGAVSMAQYSLLTQAGFAPDMVAGHSFGELSALCAAGVIS
NEDYVELAFARGHAMAQVPSDTGTQVDLGTMFAIILKQKNDIDALNSCLAQFDGVKIANY
NAPTQLVIAGGTEQTQLAAKAISELGFKAIALPVSGAFHTPLVGHAQKPFAKAIDKAKFS
APSVALYANGTGQLHPSDGKAIKAEFKQHMLQSVRFSEQLQAMYDAGARVFVEFGPKNIL
QKLVENTLGEHLNELCLVSMNPNPKGDSDSQLRLAAVQLAVAGVALTDVDPYQAITSQEI
AEREAPSAMNIKLTATNHISAATKAKMAKSLATGSVTSQVQYVDRIVETVVEREVEKIVE
KEVIVEKVVEKIIEVEANQVAAVEMKQTSPSVAQGLSNQQQATAQLNPSTPNVSGDALTA
FFSAQSQTAQLHQQFLAIPQQYGDTFTTLMTEQAKMASQGIAIPESLQRSMEMFHQHQAQ
TLQSHAEFMQLQSSSSQAALAMLNNAPINFTPAVAQPRVTAPAPAPVAPVAPAPVAPAPF
AATTVAHNAAPVAAQAVATRPAINTPVAPVVQTAPVAHAPAMTVQVAPAAPALVMPAVVM
PEVTSVAPATSGLSAALVQQTMMAVVADKTGYPTEMLELGMDMEADLGIDSIKRVEILGT
VQDELPGLPELSPEDLAECRTLGEIVDYMNSKLPAAGQVVVSTTAPTAPAANGLSAALVQ
QTMMAVVADKTGYPTEMLELGMDMEADLGIDSIKRVEILGTVQDELPGLPELSPEDLAEC
RTLGEIVDYMNSKLPVVSVVAVAPPANVEATPAQVPANNGLSAALVQQTMMAVVADKTGY
PTEMLELGMDMEADLGIDSIKRVEILGTVQDELPGLPELSPEDLAECRTLGEIVNYMNSK
LPAVGSVIVATHVTTAAPAASGLSAALVQQTMMAVVADKTGYPTEMLELSMDMEADLGID
SIKRVEILGTVQDELPGLPELNPEDLAECRTLGEIVDYMNSKLPVVSAVAVAPAANVEAT
PAQVPANNGLSAEKVQQTMMSVVADKTGYPTEMLELSMDMEADLGIDSIKRVEILGTVQD
ELPGLPELNPEDLAECRTLGEIVSYMQGKLGQNVAPISAVVQPEPTIDLPPHDLPPHSEV
VLKKLPAAAELTQQSAQKALPRVFAKDACIIISDDGHNAGVLAEKLHAQGLTVAVVRSPE
SLVASASPLNSHIASFTLAAIDDTSISAVINEIKTLGQVAGFIHLQPQHKTSADAKGLVL
SSAAKASVEQAFLFAKHLQPLLTTAATANTSSSFISVSRIDGGFGYLNHSQIARSELNQA
ALAGLTKTLSHEWPNVHCRALDIAPALDAKQLANAVIAELFATDKLLEVGVSESGVSEAG
ATETLARMTLVAGKADTRHSAANLTSADKILVTGGAKGVTFECALSLAKRSKAHFILAGR
SSQQAIPAWAQGKNNSELKAAAIAHIQSLGEKPTPKQVDALVWPVQSSQEITSALQAFTA
VGASAEYLSLDVNNPDAIASTIVPITELSPITGIIHGAGVLADKHIQDKTLDELARVYGT
KVTGISNLLAALDLDKVKLIALFSSAAGFYGNTGQSDYAMSNDILNKAALQLAQQLPNAK
VMSFDWGPWDGGMVNPALKKMFMDRGVYVIPLKAGAELFASQLLSNTGAQLLVGTDMQGS
APHDDTSNKVQETEGSNLKKPEADLTTDASDPHALLNALNPSAVNISAVKLQRTLDPKAM
IFIEDHCINGNPVLPTVCAIQWMREAAFDVLKQPVKVQSYKLLKGIIFDTVTLEKGALEN
GAPITLELELAPIALTDKAAKDTDECLSGQFSALISFEGRPQYQAILVIDDAPSDNLATN
SKATAFDAHSLAWLSAITTASSLYSDGTLFHGPRLQGIEYVVKFDDASLIAKVSLPHVAL
ADCGSFVPNLAPKGSQAFAEDLLLQAMLVWARLKYGAASLPSSIGEFISHAPFAFGDKGY
LVLEVVKHSGRALEANIALYHQDGRLSCEMNNAKVTISKNLNGAFLANKVANKSIESVEA
KVE
>A0A1V2RFT7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MRSDGDQAVAIVGAGCRFPGGGSGPEGLWRLLLRGTDVITEVPRSRWDLERYYDPDPDTP
GTMYTRWGGFLPDIERFDAAFFGIAPREARQMDPQQRLLLEVAWEALEDAGIRPGDLSGT
RTSVFTGGLGVDYFLAHARDAGIAGIDPWYATGKESSFTSGRLSYLLGLNGPSLSLNTAC
SSSLVAVHLARQSLLTGESDAALVGGVNLLLSPELTVFMCKAGAMAPDGRCKVFDAGANG
IVRGDGCAVLVLKRLDDALADGDDVLAVIRGSAVNHDGQSAGLTVPSATAQQRLITDALT
AARIHPHDVGYVEAHGTGTPLGDPIEAWALGDVLARGRSAEDPLVIGSVKANLGHTDGAA
GITGLLKAALVVRHGRIPPHLHLKEPNPNIAWDQWPLRVPPTEGPVDWPGPAGRPRIAGV
SAFGLSGSNAHVLVESPPERATAPGARAGGTDGRALVLPLSARSAAALRDLAAAHRDRLG
GQEAEEREGADGFADVASFVRTAAVRRTHHAEHRLAVTGGSAAELAAALDAFTAQAPVVG
ERAGPGGVCFVFSGQGGQWAGMGLRLRAAEPAFREALDRCDALIREAAGWSVVEELSADG
DASRLADTEIAQPVVFAVQVALAALWRSWGVEPSAVVGHSMGEIAAAHVAGALDLADAVR
IAVLRGRLLQHAAGQGRMAAVALPEDETERRLAPYGERLCVAAANAPGSTVVAGEPDAVE
EFTATLKAEGLTCRTLPGGYAFHSPQMAPFEPELVGLLDGLAPHEPRVRIVPTTPGDGRF
DAAHWGRNVRRPVRFAGAVAELLDAGHRTFVELGPHPVLAQPLTQSLEAAGLDGTVVPSL
RRDTDDVDTARASLAALFTAGADVAWDAVAPAGEGVDKRLPRYAWQGERLWFETPQAAGP
DAQVAAGGLAALHGELRLYDAAGRVVAEATGLRLGAPGDGAPTAAAVPGAPAVPAVPAVP
AVSAAVETAGHRPDPAELADLVARKAAAVLGLPQGGTPARTQGFTELGMDSLGTVELARQ
LQQALGVRVPKTAALDHPTVERLAAYLDTRLAAAPAARAQAPAAVPAPGPVAAGVTGHEP
IAVIGLGCRFPGGASGPDAYWRMLRAGTDAIRPAPEGRFGGSRVWHGGFMEGVDEFDAPF
FRIPPREARVMDPQQRMFLEVAWEALEHAGQPPAALAGTRTGVFLGMNSTDYAGIVTAHP
GNVDAFYGTGNSFTAAAGRLSYLLGVHGPSLAVDTACSSSLVAVHLAVASLRSGESELAV
AGGVNLILSDVIHRSTSAMGALAADGRCKTFDASADGYTRGEGCGVVVLKPLSAARADGD
DVLAVLLGSAVNQDGPSSGLTVPNGPAQEDLLRRALADAGVAPGEVGYVEAHGTGTPLGD
PIELQALGAVLGERDGSCLVGSVKTNVGHLEAASGVAGLIKTVLALHHREIPPHLHFTEP
SPDIPWDELPLAVPVEPTPWAPGAARRVAGVSAFGFSGTNAHVVLAEPPAGAEPERGAAP
GGAAAGERRVHALPLSAAGRNALLAQADAWGALLADGDDGAAPALEDLAYTAALRRTHLE
HRVVVVGDDRRQLAERLAAFGRGEDVPGVAAGQAGAEPRRGPVFVFSGHGSFWRGMCRDL
LRESPVFREAVERCDRALRPHLDWSIAEVLAQGHEPAAELDQQFLLFGVQYALTQVWRGL
GVEPAAVTGHSMGEVSAALCAGALDLGQAVEVMVHRTEVLKDLMGRGGMAVVGLDAERTA
EELTGYEDRLCVSIVNSHRSTVISGETAALEEVGARLKARNVFFRPVAAGAPAHSPVAEP
MRRELVARLAGLRPAEPVVPIYSSVTGGPVDGPLDAEFWGRNLRHTVWYADAVRALAADG
HTTFVELSPHSLQLAPTEHELDAAGVADRLLVPSLTRDSDGPVALMTAFGTLHATGRPVD
WERLHPAGGRLAAAPRYPWQHKRYWVEHEAAPGAAPAFGGAAGGGARHPLLARELRAAGG
PRTRIVEADVDAELAAGTGAEPVGGHLRLPAAAWLEMALAAVAGEGGRVRRLEDVSLPGS
CLTDPAVGSVAQLTLTPEPGGAFAFAVHARAAGDGEGPARPLAAGRAVPGSGSAAPGAVP
APGVRGAPDARVTEWFAARGGGGALRAVSAVRGADAVEVEVECAPTALRWRMRPDVLDAA
LRLPALLGNADEAARDVLPWHIASAAVYGTPGQRLLIGARRTPGADGELCADVWVATPEG
GLIAEARGVRLAPPPGRLLDAAELRSVADSFYRVDWRERPHEAAGAAEAQEPAEAAGGWL
LLADGGGVAQALAGLLEERGGTVEVLAGAREEAEVTAALRALHRGPGCRGVVHLAALDLP
EGAPAADGLAAAAAVAASVPAVAAAAQAVTGAAGGARVHYVTRGAVTVGAGEPPAPLHAP
VHRLAGVTGVERPAVWGGVTDLDPFGDGPAQDASWLLAELLAPDGEDHLAVRAGRRLGAR
IVRCAEPEPVLVPPAPRADRTYLVAGDDGGLAERLAAWLTERGAGRVVAAGPLADPGTAR
DTAGALVKEAEQAGAPLAGVVWAGADWNLGPQGAAPPAADEVGRLLAERAAGAWLLHDVC
TEAGLDLDLFAVFTSVAALWGAAGAGHQAAPDALLSALAAHRRALGLAACELAWAPWDGV
GRLDENSRSLLLRSGLEPLSPEAGTRLLDHALAGAHDAVAAAAVDWSLLLPLYQQSLRWP
LFDEIAASALAAPDGTDELLARLAALPPGERDDLLLDLVLAEVAVVLGMDGADDLEPRQG
FFEIGVSSITAVELRIRLERRFACALPATLAFEQPTAEAVARYLAADVLGLPAADATGTG
SGTGTGTAPQPEEEAAAQPRPESAGDGDDLLALLDEQISAVNDLLGKGAF
>A0A679JIK1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Methylobacterium bullatum|TrEMBL
MVSSIKSVCESNVIKRTDIAIVGRSCRLPGAASVDGLWQLLSEGRCAVGRIPEDRWSLER
FGHPRAQERGKSYTWSAGVLDDIWSFDPGVFGISPREAEQMDPQQRLLLELTWEALEDAG
LRPSAVAGSQIGVFVGASSLDYGNLRVLDTSSGDAYAATGNTLSILSNRISYIYDLKGPS
FTVDTACSSSLVALDAAVAAIASGRIDTAVVAGVNLLASPFNFICFSNAQMLSRTGLCQA
FSANADGYVRSEGGVVLVLKSARQAARDGDTVRGVIAASGVNSDGRTTGISLPSGYAQGA
LLEQVYREAEIDFDAVAFVEAHGTGTAVGDPIEAGAIGGKIGRPRKEPLPIGSIKSNIGH
TEPVSGLAGLLKASLALEHDLLPPSLHAAELNPDIPFTKLNLSVVTAPLAIPRGRGERFA
GVNSFGFGGTNAHIVLTDGAPAPAASDAGRPPELLLLSAQSRAALNELALDYAERFEQAD
DAQTVRIAAAAAHRRERLSTRLAMPLDVDLPATLRAVADAEETDIARVGTAVDRNAEVAF
VYSGNGSQWVGMGREAYERSATFQSAFDRIDVLFAEISGWSLKEALFAEDLAERMVLTRV
SQPLIFAISSASTTALKAAGLVPSFVLGHSVGEIAAAEGAGILSLEQAVKVIFYRSQHQE
TTRGLGTMAVLLAPVEEIEIFLKDYPSLDIAAYNSPKAVTVAGPVADIDAAMKALARKRR
RGRKLDLAYPFHGRLMNPTEKPLLRDLAGLTPHPGAIAMVSTVTGTVLSGGEFDADYWWR
NIREPVRFSDAVQEATRKGARIFVEVGPRATLLPHIGDCIEPLGIENATVGVLTNKPVGS
DPFARALASALVHGAAVDEAVVFGENPKGDVALPSYPWQRRPFRLSETSEGVGAATARAY
HPLYGSRLSPDGLEWLGHVDIATVPDLDDHRIDGQAILPGAAFIEMALGVAREAMRSDDV
VLAEFEILSPMVFAEEALREVAVRLSGSGNQIQILSRPRLTQAGWQLHASAKVVDGTFAA
RPRQDIDIPAENAVEGAGLYRLAAASGLDFGPSFRQVALSARVDETTIVSQLKPAEADLR
FGLVPARLDACFHGLILLFADLMGEGSTKAYVPVRFGEIRLIRPGAVIARAMIRTRRCNE
RSILADFTLVDEAGEVIATLREGRFQALRTKSGQDLAAYAIAQRSELATEPTAIPLDRRA
RIADAVRPGIKAALAPADAALSPGHLLLEGWATSLAYRMAEGLQRSGTVAIDERVPEAMR
PWLLNALYALESSGLATLDGTRWTLRKDVTLPAPDEIMRWIAADHPELSAELVLTADLGA
VVARLVAGELASPPTLSQNALDAFVLRSATARASSDVIAAVCEGARADLPKDRSLRLLQV
GFGPLSAQAAAIADDIAAQLTVFETDRRLAERARLALPRGVTVIEDETHLTEGGFDAILA
SNVLHRSERGLLGKVADALATGGFLLAVEPGASLFRDLVFGLMPDWFESVDGMPLGRLDD
ITGWQRSLSDTGLVRIAVDRAASANGDDLLFLAEAPVRAKAATGQTFTFIIGSRDSFAAE
TASSLATLLVAAGVHVSIILDSEQSLLELERETPDTVVFLAGAFGSGGEAADRLRERCLG
LKRCVEHLGTRQTRLWVVCPGATRHDGAGAVEAGLWAFTRTLANEVANLDIRRIDLTEAM
PTKIASERLRDVILSGTPETEIVLDVDATRVIRFSPGQLSRRPAVDAVPAPAAQLERSAT
GGLNDMRWGPAERCTPGRGEVEIAVEATGLNFRDVLWALSMLPEEILEDGFAGPRLGLEV
AGRVVSVGKGAAAFKVGDRVVAFAQSGFSTHIVVPELVVAPSPPGLDPQAAATVPVAFLT
AYYSLVSCARLRRGEWVLVHGGAGGVGLAALQIAKLKGARVIATAGSREKRALVKALGAE
HVLDSRSLAFVDEVRRITGDGVGVVLNSLFGEAMERSLNCLKPFGRFIELGKRDYVANTH
IGLRPFRRNLSYFGVDLDQVLQHQGEDGARLFREVMALFTEGGLKPLPFQPFTADEVSDA
FRLMQQSGHVGKIVIAPPKPGSIVVERKSDFRVSAEGVHVVTGGLGGFGIEAARWLADRG
ARHLVLVGRKGASSPEAKQVVADLAVRGVSVAAMACDITSRRAVDDLIEEVESGGRKLAG
VIHGAMVLQDGLIANLDAASLDAVIRPKVVGAEHLDAATRGRSLDYFVLFSSATTFIGNP
GQGAYVAANGFMEGLARRRRALGLPALAVAWGAIGDVGVLARNRAVMETLAGRVGVTPMD
ARRSLDLMAEALEGQGSSPDDAVLAIASMHWGKARERLATMRSPSYGDLGSDQQAEAGTV
ATIDIGGLLKSQDLDAVRKTVSDAIVEDIARILRLPKDDISRVRHLSEIGLDSLMGVELG
ASLQERFALDAPPSGISSGLTVVELAETLIQSVAAPVDDASAAVMSLAQRHASEGVDVRT
LEPFHELVEQNSLQIKEILP
>A0A3E2N0X2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium marinum|TrEMBL
MTTPVPKREWKEVVLLAGGGSDVAVVCLPTLTVLSSPHAYLDVARAMAGRHSVHALSLPG
FDPDDALPQDREVVLEGAAQAILHAVGDHPHLVLAGYSSGGVLAHALGSYLAERHQRKPL
GVALIDTYLPSQIVNADNPDQVGVNETGALFSRRVTSMARELDQLNATRLTAAASYAALF
GTWEPVASAVPLLNMIAMDETAACERVREERINRWRVATAEASYSVVEVPGDHFDMITTS
SDATTTALHGWISGLIRAG
>A0A086JHY7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii GAB2-2007-GAL-DOM2|TrEMBL
MTEAATPQNVTSPADLSKQNVSFRPGVNAVEFVSGYSHAGSVVCSLPSPIFFNKASSSNG
NCESNASTASSSAALGTEASSNVRTGTVLIFDCGSGNTWQHLRQWLSDEGASHIVVVHAC
AEEGADTLGVKTLHPSRVNGGQGCSQTLIKEVKCRPHHPEEVVELFKLLKEGLHFPLVRG
IFYILGEKLDSLLANQTTSSVHDMMKTASGAWSIHHALGHLGMEADLDFFIFFSSISALF
GSISQSISAAVHASLDALAYYRRHLGLAATSIQWAPWADGSSATSPQIVRHWLEKGGVSS
VRNPLAAVSAILKNHTAIGAVVACFHADPTIMHEMGETDQECTFLSSGPAANTRDSTSGN
VKVRTNPVKSRVFQNVSPSTDTCGENHKDELLVILTQLVRREVIEIASCYVFFEGNNLST
DESLVDLGLDSLSAVELRHTLQQRFCVNIEPTFLQANATIDSISALLVTHVATSLTGALP
VLPLSCPGLASAVDDCALVSLALRLPGRCDSLDAFWASLQSDSGYCRPGASEACDQCFMH
RAGSGELPAESQSIGTNLDARKGFCWLSNRDAFDSHFFGISFTEALATDPCHRLLLEATY
EALCKLNTEQQSGTSGTPIAVFATSSSTQMRASLPSYTKPASSQNTQDNNGCLAASFLSY
HLNLTGLAVPIDGSDSASLIALDLGREHLRGTDSVCQAVVVAAGSLLPICSHGWPSACTS
PTIRRFRGRDDYAFPDRETYAVPRGEGIVSVVLQRLSVARENGNSPMAILKGISLIRMGR
GERPIPSQWRTADVKLRRKTIVEALKMSRVEPRTVAVLETDGLTGSQAEDAYTVEAMADI
FGPRHLAESCSPLVIGNASLHIGQAREASGLATLAKLVLMLERGYAPPIPRLRRLHPDVK
RGILPSGFVMFPCKKMDLLAFRQHPDHVYGPNEKRDQKEGRPLIGCVSSLGSDKTSGCFI
VESSPRRHGRTSDTRVSLERAVPLAGTKDACSHNYLHVRSTDGSESEIRGDDRAVWLFCD
DLWGLQSVGRGLYCSDPAFAALLEQAERVLGNRIPQPLSCLLYPSTTAEFQKAEDALAFP
RIAAFVLFSLQWALATCLRHQEGEPTAVMGLGVGEIAAAAVAGILSLEDAVELLELLSSE
TRTCDNRNKPMPGGNVNSGGLFDRGNSGTGGCGVAQDCKSPWVLCGLNKTPTSESAALEF
SVLESRRGSSSRKSSETPTSNTTPHNRDVFQERFSRKPRRATCPSPIIRHAWEKVAHGNP
ENDEEAELECPSSQSRRANCPSPAIQHACEETAHGNHANDGEADLLMDLFRFRPEPSEPL
GQVTARIALRNATCLFISTVSGRLATDTLIRAAEYWDPLVPKTQRVHRAVETAVQVAKTA
KLVCIGCSAQDGVHLSVGLPSVHPISPSPLRIFCFTGSSPSPQLLAPCESASGSSPRVAV
VEHHGADSNLGGGAPWWKHLLFRLPQLEGFPSGCSASTRLLADRLVADVPTPDNHMINNP
QTAAVQGAGETLGTLREGSSGEGEDGEKGYRSESVNTQHPVYKVYRRCSEPELHESELSL
LCSDTVCQPSLEKTVELFIGTGLEQQGKLSTVSSSWLVFSDIVAPSPISLYSTLAFQNED
GEQRFCTLNVASQVATVYAEKVKTQVCSIIIECKRGFKPPREIARCYFVKNQTAVGKHEP
AVSSLSRIRWLPATKLPEGWLRTRRPHVWPCKIKVTKAACPLPTRRVDLQEIYWGKRHIL
CRFRMPRNPPRDGVEKSTQLIAILARLVTVSVGVAATCVLHETETSGRYSHSHPGPQVED
DQKTHMDALWVCPYVPFSECWCVIRHRRNGSSIKEGKGRDWETCDVEIFSENGTAVAVVL
GFGIQSHALSMRMMGGRGNDGDSSVSTTVCVA
>A8FY83|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Shewanella sediminis (strain HAW-EB3)|TrEMBL
MSQTSKPSKKPLASDKKTVKVDKSSAKTAEPQQDSQADSRLNKRLKDMPIAIVGMASIFA
NSRYLNKFWDLISEKIDAITELPSTHWQPEEYYDANKSTPDKSYCKRGGFLPGVDFNPME
FGLPPNILELTDSSQLLSLIVAKEVLADAHLPEGYDRDKIGITLGVGGGQKISHSLTARL
QYPVLKKVFANSGISDEDSAMLIKKFQDQYVHWEENSFPGSLGNVISGRIANRFDFGGMN
CVVDAACAGSLAAMRMALTELTEGRSEMMITGGVCTDNSPSMYMSFSKTPAFTTNETIQP
FDIDSKGMMIGEGIGMVALKRLEDAERDGDRIYSVIKGVGSSSDGKFKSIYAPRPEGQAK
ALRRAYDDAGFEPHTLGLIEAHGTGTAAGDAAEFAGLCSVFADGNDTKQHIALGSVKSQI
GHTKSTAGTAGLIKAALALHHKVLPATINISQPSPKLEIEKSPFYLNTETRPWLPRVDGT
PRRAGISSFGFGGTNFHFVLEEYNKEHSRTDAEKAKYRQRQVAQSFLVSAASKDALITEL
NALATAAASSEFIIANAAKDYSLRELDSKSARIGLVANTSEELATQIKQAIAKLTSSTDD
AWQQPGGTSYRANAIEGKVAALFAGQGSQYLNMGRDLACYYPEMRQQFVAADKVFAENDK
TPLSQTLYPKPVFNRDDVKAQEAVLTNTANAQSAIGAISMGQYELFTAAGFNADMVAGHS
FGELSALCASGAISTEDYYKLAFARGDAMATKAPAKDGVEADAGAMFAIITKDAKDLEAV
EATIAKFDGVKVANYNAPTQSVIAGPTASTADAAKALSELGYKAINLPVSGAFHTELVGH
AQAPFAKAIDAAKFTKPSRALYSNATGELYDNTAAKIKASFKKHMLQSVRFTAELEAMYD
AGARVFVEFGPKNILQKLVQGTLADKAGPNKTGIVAISINPSPKGDSDLQLKQAAIQLAV
AGIKLDNIDPYQADIAAPEKKSPMSISLNAVNHISKATRAKMAKSLETGTVTSSTIVEEK
VIEKVVEVEKVVEVEKIVEVEKVVERIVEVPTVIESQVVSQNAPVLNKEPSAVLSNKPSA
AVSNDALTNFFAAQQQAAELHQQFLEIPQQYGETFTTLMTEQTKLAGNGIAIPESLQRSM
EQFHQLQAQTLQSHTQFLEMQAGSNTAALSMLTGTPTQILSQPQAKTVKPVAPVQTAIAQ
PAPVQVAAPAPVAQVQVAPVQVAKPVQTVSHQAAPAPVQVTPVAVAPAAQAETALSATLS
SETALSAQRVQATMLEVVAEKTGYPTEMLELEMDMEADLGIDSIKRVEILGTVQDELPGL
PELSPEDLAECRTLGEIVSYMNSKLPNTSAAATPVATAASAETALSAQTALSAQRVQATM
MSVVAEKTGYPTEMLELEMDMEADLGIDSIKRVEILGTVQDELPGLPELSPEDLAECRTL
GEIVAYMNSKLPSGSSTAQATSAAGSLPSQAAEGSLSTGLSAEKVQSTMMSVVAEKTGYP
TEMLELEMDMEADLGIDSIKRVEILGTVQDELPGLPELNPEDLAECRTLGEIVAYMNSKL
PSGSSTAQATSAAGSLPSQAAEGSLSTGLSAEKVQSTMMSVVAEKTGYPTEMLELSMDME
ADLGIDSIKRVEILGTVQDELPGLPELNPEDLAECRTLGEIVTYMNSQLAEGSKLPAEGT
NTSAAAAPVATAASAETALSAQTALSSTLSAEKVQVTMMSVVADKTGYPTEMLELSMDME
ADLGIDSIKRVEILGTVQDELPGLPELNPEDLAECRTLGEIVSYMNSKLPATNSAAAAPN
ISAAEGSISATLSAEKVQGTMMSVVAEKTGYPTEMLELSMDMEADLGIDSIKRVEILGTV
QDELPGLPELNPEDLAECRTLGEIVSYMNSKLTNAGAAAGAAVSGAVKSVADTITSSLEL
PPHSEVALKKLNAADQINDCFAADATLVITDDGHNAGVLAEKLTKQGLKVAVVRLPKGAA
QSPLSSDVASFQADNLDESGINGVIAQIEQQLGHIGGFIHLQPDADTSNVSDAVNLSNDS
FTHVSQAFLWAKLLQPKLTTASEKRRSFITVSRIDGGFGYLDTKQLQDAELNQAALAGLT
KTLSHEWPTVFCRALDIATNLDATHLADAVTNELFDSNAQLPEVGLSLDAKGNVSRTTLI
AGEASSKHAASSLDSADKILVTGGAKGVTFECALAVAKRTKSHFILAGRSELLAIPTWAE
NKQISELKPAAIAHIISTGNKPTPKQVESLVWTVKSSIEINTALEAFAQVGASAEYVSMD
VTDTAAITAALKGRSHEITGLIHGAGVLADKHIQDKTVEELGRVYGTKVNGLKALLAALD
SSKVKLLAMFSSAAGFYGNTGQSDYAMSNDILNKAALQFTARNPQAKVMSFNWGPWDGGM
VTDALKKMFTDRGVYVIPLKAGAELFATQLLSETGVQLLIGTSMQGGDDNSKNAEGSATG
NASVKKLNAGEVHNALIPQGLATKGPLAPVSLIRALNPNAMVFIQDHRISGNPVLPTVCA
IQWMREAASEMLGTQVKVLDYKLLKGIIFDSSDVQEMTLELTPSGNDQMNALISSQGRPQ
YKATLVSAEGDVDAASKSFTELGEAVTDAAELYSNGTLFHGPRLQGIKQVFKFDNKGLLA
SCQLPRVSDSDCGQFVATQHIGGSQPFAEDLLLQAMLVWARLKYGAASLPSAIGEFISNK
PLAFGDKAVLELEVIKTSARSLEANVALYHENGELSAMMKGAKVTISKNLNSAFLNESAK
GEQA
>I7FMV0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)|TrEMBL
MDENHSDSNLPEGTEPAGRPAPRTDMTVNEMREWLRNWVANATGQSADAIDESTPMVELG
LSSRDAVAMASDIEDLTGVTLTATVAFRHPTIESLATVIIEGEPEPEPYDEDEDWSRTRD
VEDIAIVGVATRFPGDLNTPDEMWEALLEGKDCVTDLPEDRWTEFLDEPRIAERVKKART
RGGYLTDIKGFDSEFFALSKMEADNIDPQQRMALELTWEALEHARIPASSLRGESVGVYI
GSSTNDYSFLAMSDPSIAHPYAITGTASSIIANRVSYFYDFRGPSVAVDTACSSSLVATH
QGVQALRAGEADVAIVGGVNALVTPLVTVGFDEVGGVLAPDGRIKSFSSDADGYARSEGG
GMLVLKRISDARRDGDQILAVIAGSAVNHDGRSNGLLAPNPDAQAEVLRKAYKDAGINPR
DVDYIEAHGTGTILGDPIEADALGRIVGKGRPADKPALLGAVKSNLGHLESAAGAASLAK
MTLALANDKLPPSINYAGPNPYIDFEKERLKVNDTVSDWPRYSGKAIAGVSGFGFGGANA
HVVMREVLAGDLVEPEPEPEPEAKPEKSEADAVYVGGVRMDEYGEFIDEDEPAEGGDAYP
SYDEDSYELPGITEAAQRLLEQAREELEAKEAEEPTKQLVPLAVSAFLTSRKRQAAAELA
DWIDSPEGRASSLESIGRSLSRRNHGRSRAVVLAHDHDEAIKGLRALAEGKQHPSVLSAD
GPVTNGPVWVLAGFGAQHRKMGKSLYLRNEVFAEWINKVDALIQDERGYSILELILDDNV
DYTDATCEYPIEVVQLVIFAIQIALGELLRHHGAKPAAVVGQSLGEAAASYFAGGLSLAD
ATRTICSRSHLMGEGEAMLFGEYIRLMALVEYSADEIKTVFSDYPDLEVCVYAAPTQTVI
GGPPDQVDAIIARAESEGKFARKFQTKGASHTQQMDPLLGELAAELQGIEPKPLTTGYFS
TVHEGTFIRPGSAPIHDVDYWKKGLRHSVYFTQGIRNAVDNGHTTFLELAPNPVALMQVG
LTTASAGLHDAQLIATLARKQDEVESMISAMAQLYVHGHDLDFRTLFPRRSKGLAGALDF
ANIPPTRFKRKEHWLPAHFTGDSSAVMPGNHVATPDGRHVWEFVPRGKTDLAALVKAAAA
QVLPDAKLAAFEQRAVPADNARLVTTLTRHPGGATVQVHARVEESFTLVYDAIVARANGA
GVTALPVAVGAGVAVSGDVAGEGAGASVIEDDEPDAEILQDNLTAGAGMGADFQKWDPNS
GETIGQRLGTIVGAAMGYEPEDLPWEVPLIELGLDSLMAVRIKNRVEYDFDLPPIQLTAV
RDANLYNVEELIRYAIEHRDEVEQIAESQKGKTAEEIAAEQSELLGGASTVAELEAKLAE
AGHPLAAKDSEDSENSEDNAAGAAAAAEASAVEGLEIPPPPTDPTGPGGAPIPPPPSDPS
GPAQAASATDAPAGTVNKATAAAAAAKVLTQEAVTEALGADVPPRDAAERVTFATWAIVT
GKSPGGIFNELPTVSEETAKKMAERLSERAEGTITVEDVLGAKTIEGLATIVREQLEEGV
VDGFVRTLRPPKEGSNAVPLFVFHPAGGSTVVYEPLMKRLPADVPVYGLERVEGSIEERA
AEYVPKLLEMHKGPFVLAGWSLGGALAYACAIGLKQSGADVRFVGLIDTVLPGEPIDQSK
EGMRARWDRYARFAERTFNVEIPAIPYEELEKLDDEGQVKYVLEIVKESGVQIPGGIIEH
QRTSYLDNRALDTVDIKPYDGHVTLYMADRYHDDAIVFEPAYATRKPDGGWGSFVSDLEV
VHIGGEHIQAIDEPYIAKVGAHMSEALNRIEAQASKEDGAK
>A0A655HZ14|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MSTAGTFENLRLELIPDADAPLGPGQVRVAVSAIAANFRDVMIALGLYPDPDAVMGVEAC
GVVIETSLNKGSFAVGDRVMGLFPEGTGTVASTDQRLLVKVPAGWSHTAAATTSVVFATA
HYALVDLAAARSGQRVLIHAGTGGXPTPTHRWGPARSGWPCAPSPRTSATS
>F9UAS6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Thiocapsa marina 5811|TrEMBL
MSGRFPGASDARQFWRNLLECQESITFFSPEELDRDSAYPVDDPSYVRAKGLLDGVEFFD
ASFFGIPPAEARMLDPQQRILLELAWAALEDAGYGSDRRPEKIAVYVGTNWNRYMELNLA
SNPSLLDRYGEFNAALANEADFPATRIAYKLNFKGPSVSLFTACSTGLVAVSEAVKSLLS
YECEMALAGGASVSLPQRRGYMYQEGGMLSKDGHTRTFDASSTGTTFNEGAALVLLKRLE
DAVADRDHIYAVIRGAAINNDGSDKMSFTAPSVTGQAEVIATALAAANLDPDSVTFIETH
GTATPLGDPIEVEALSQVYERSATAGPGSCVLGALKSNVGHMIHAAGTAGLIKVALAVEQ
GVIPGTLHFREPNPALNLERTRFRVSAETHAWISEQSPRRGAVSSFGVGGTNAHVIIEQA
PLLTPSDADTAVPVALLSARHQAGPEQSARALAERLEDRLPPNLGDVAYTLAVGRSFYDY
RLAAVAEDAVEMVRALRSGRGPRVVVGRADSPPGRLAFAFPGQGAQRPGMGAELYRRQPA
FRAAMDECFLVADRELDIDLRELTIAAESEDRAAGLLEQTRYTQPALFAIGFALARYLGS
LGVRPDVMIGHSVGEFVAAALAEVMTPSDAMRLIIERGRLMYAMPAGAMLAVGLGEADAA
VAGAELGLSIAASNAPDLTVLAGRPEQVDAAERKLDARGIRCTRLRTSHAFHSEMMDPAV
EALGEVLSRVVLRPPQIPIVSTVTGEMLTDEQAVSPRYWQSQLRVPVRFAHALETLLAVG
RCGMIELGPGGTLTSLAERQSDGGHVFAAALGTRGVSEPESVMVALARLWVNGADLDWAG
MFEGETRARVSLPTYPFERQRHWIDPGYPTPERSDQQAPVVPAEPAGAAVTESPEMLNTQ
EHDARILERVIELFEDVSGMDLRKSDTGQSFMALGFDSLFMTQISAAINREFAVPVSFRQ
LSGDLDSLQALARHLAGLIPPEATPVTVPPPTPLPVPPTASVAASVPASVSPSPGGFLQS
GTQLEVLVSEQLRLMGRQLELLAGGQSAAVPAATMTTAPSVANLGTRSEGLAIKAPDIDP
DSLYPGKLPRDPDDDRPTGVGSWDDLDPRRQAALRTFIQEHGARTAASKAHIARYREHHA
DPRTAAGFHRVWKEIVYPIVCERSSGARLWDLDGNEYIDLLNGFGPNFLGHSHPEVTEAI
GREMSRGFEIGPQQRLAGETAELVCELTGMDRASFVCTGSEAVQAAIRCARTYTQRDKIV
MFRGDYHGNFDEVLVRGLASGGYLKTLASAPGIPRESVANVIVLEYGHDSALSIIEEIGD
QVAAVLVEPVQSRRPELQPREFLHRLRSITQSKGALLIFDEVVTGFRCHPGGAQAHFGVR
ADLATYGKVAGGNLPLGIVAGRRAVMDTFDGGTWAYGDDSSPEAGVTFFAGTFVRQPFAI
AASHAMLNILKREGPQLQRRVSMTTEGFVARVNTLFKNYDIPFEMPCFTSIMYLRNRDKS
ELGSLLWYYLRHHGVFALEGFPTYMTASHTPDDIDRLVEGFRLSIERMIADGMLHSAKVT
QAEEGIPASTLRPPVPGARLGKDPRGNPAWYAPDPDRPGAYLLIT
>F0SIS4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Rubinisphaera brasiliensis (strain ATCC 49424 / DSM 5305 / JCM 21570 / IAM 15109 / NBRC 103401 / IFAM 1448)|TrEMBL
MINRETQLSPAKQALLQIRELKRQLAAARHTPTTDIAIVSTACRFPQSAETPEAYWEMLR
AGQSQISEIPGDRWDLEAFYDEDSQVPGKMYARWGAFLNRVDSFDAEFFGISPREATWVD
PQQRLLMETSWEALERAGWTDSSLSRKTGVFIGWMHNDYQNEASDSFLNLNPYIATGAAG
SFLSGRLAYYLGLEGPSLAIDTACSSSLVALHLACLSLSSGECDAALVGGVNVIVSPTTN
ILTCKLQALSPHGHSLAFDARADGYVRGEGCGVVAIKRLEDAERAGDPILAVIRGTAVGH
NGMSNGLTVPNSQAQERVIREALQRARVSPSEIDYLEAHGTGTSLGDPIELHAAAAALGE
NRDASRPLYVGSVKTNIGHLEAAAGMAGLIKVVTSLQHGQIPQHLNFEQPNPHISWDKIP
VQVLTNPLEWNADQTRLAGVSAFGMSGTNAHVVIAGYSHRSASNAAPISRNGSATIAASA
TTNGHSKNGDSQPASRSPQLITLSGRNEDALYQQIRQTIPWLENKSSDEFIDAAYTLSAG
RTHFDHRLALVADSAEQAAQRLRDASRSETAEHVYVGHAAKSPRVCWQFTGQGAQYLQMA
ESLYRENEQFRNAIDECEQWSQELRGESLLQVMFGDEEALNDTRWTQPAIFAVQKGLCEV
LSLWGLKPDYVMGHSVGQYAAACTAGVMTWEQGFFLICERGRCISELERAGVMYAIFAPA
DQVDDAIAAHPEVSLAARNGTHQVISGKTTPVERLAAEFTERGIRCKQLQTSHAFHSALM
DPALNPFEKQAAQVAYKQAAIPLVCNVTGDILPADFEFTPAYWANHIREAVRYSDGLQAL
QSEGCEILLELGPQGVLTNMARAVWSGEPASLISCLQKKTEDTTTLLEAIGQLYVHGVKP
DFRQLYSEKRRILVGPTYPFQRRRFWGPPKPKASHAISHTAHPLLGSPYSLAGVTDEKRF
ESVIEPDSPAWLPDHSVMDDVIFPGAALLEMAMAAGEGQQIQNAVFEAPVQPQGRTRLQS
VLKTSDGKQSFEVYAAAEGEQAPWRRHFRCELAAASSPSSTVDLVSLKQQFSESIDPTEF
YETLAGIGLNYGAAFRVIESLATSETGVLAQLQLRGDVRGYQLPPTLLDGALHSLAVGLL
RDPDSDLFLPAGVGELNSSAALTDELWCHAEWTQPTGDERFADLTLYNADGVSLLEIRDL
KVKRLSRAALRKSRKDQPTRLLYDIRWQDYRLPDNSLDPKTWLVVAASEQAGAPSVTEAD
ALGMLLTERGHRAVHVDLAGESGELVEQEGRFLIDGHDASQWTQLLTELKAADISTLDGI
AWHIDSKSDQSPLAVADQHCMSVITAINAFTKAGIRGIECGFQIVTCDGVSTGADSLPVI
PAHSQFWGFGRSLAAEQPTFQIRLVDQSSAVDSDSSPKAAFLADYVLNSTPENQIAIRNG
QYFIPRLQRVSSDEAEQVNFPISSEGACLITGGLGMLGQETARWLAAQGAGHLVLVSRRP
PNEATVATIEEIRSAGTEITVAQADSSDREAMSALLKRFGTDLPPLKGVVHAAGVLQDGL
IADQTSERFEKVLSPKVIGAQLLHELTEPMELDFFILYSSAASMLGSPGQTNYSTANGYL
DGLAQSRIQAGLPALSLNWGPWTIGMAADENIARRMELQGIVPLDVSAHQVLPHALSQGI
SQGLVLDVDWRRLNAASGGMSPPLLADVMPARKRSAGASSEFIKKLRALPVHERRDSLRD
SIQLEFQAILGSDELPATDRPVIEFGLDSLMAVEFSSRLQSLVGEEYAIAPTMLFDYPTI
DAITGYVLEQLGDDETPSPAAEVAKGTAPTAAEQSSAPRVLERDNIALVGLSCRFPGASN
AREYWQNLIDGVDAVCEIPADRWDVDRFYSKDREPGKMYCREGGFVDGIDQFAAEFFNLS
WDEACWIDPQHRMLLENCWSALEDAGLPPGSLPDPAVGVFMGIMSSDYAFLPKLEDQELL
EQFQGAGFSHSAGVGRISHFFGFEGPSVSVDTASSSSLVAVFQAMRALQERQCNLALAGG
VNAILAPVNTLLMSNAGLLSPDGRCKSFSAAADGFGRGEGCGVVVMKREQDAIRDGDRIL
ATLRGGAVAHNGTSGGVTMPNGPAQSRLIRAAWEDAGLPPQSAQYLEAHGTGTAYGDPME
LNAAAAVLGRGRPKDNPLLVGSVKANISHLEAAGGISGLIKTVLALHHGYIPRQLHFDEP
SPHIRWKRLPVRMVTDGAVWPETDERIAAVTALGLSGTNAHVVLSAKSVTTSPVSVSESE
IATDDKPELLLWSARTPTALKAMAGEHRDYLQNNLQLSLADVAGTLAQGRTAFEYRLALT
SHSMTDLIEQLEQAGEFNLENGRFCESDNGIAGQADCNVKQTWQFEPMTTSELTFASRLY
SSEPVFQEAAKSLLQSLREYQSQTKTRETPTTADEVEQVLRNASAIEELSSSGQVVLEFV
CQWGLSQLLERAGATAEKVAGYGIGQYTAACLAGSLKAEDAICLIYEQARVQNSDDLDKF
EAIADRYDFYPPAKTLWCSLDGEMVPVHRSPGGSYWKRFAAAQLEATPPIRLDEDQKSGI
VIRFAGNRSQHVNHAEDTTNTSKRERNVFCEQSVSPEKSLRKLLGDLFVAGCAIDPTRLS
SQRNRRVSLPTYPFERKRYWITDLISKPSRAD
>A0A2K8RGI0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MSSSQSEQIVEALRASLKDNARLKREYDKAVAATTAPVAIVGMACRLPGGVSTPEELWEL
VAAGGDGISGFPVNRGWDLDNLFHPDPDHPGTSYATEGGFLHDAGEFDAGFFGISPREAV
AMDPQQRIMLELSWEVFERAGIDPTSKRGKDVGVYSGIAFHDYGAGLDEVPEGLEGFILT
GGAGSVLSGRVSYALGLEGPAVTIDTACSSSLVALHLAAQALRAGECSMALAGGVTVMAA
SDAFVGFSRQRGLAPDGRCKAFAASADGTGFSEGAGVLLLERLSDAVSAGHPVLAVVRGS
AVNQDGASNGLTAPNGPSQRRVIRRALSSARLSAADVDVVEAHGTGTALGDPIEAQALLT
TYGRDRDRPLWLGSVKSNIGHTQAAAGAAGVIKMVMALRHGVLPKTLHVDTPTPQVDWSV
GAVELLTSEQPWPETGRARRAAVSGFGISGTNAHVILEEAPAPTQPTEPGPATGSSAETG
PETSPESGPETGPATGPTIRPAAASAATDPAPSPPLLGDAPVPLLVSGRGESGLRAQAQR
LLSFLEERPEVALPDLGWSLASGRAALEQRGVVLAADRDGALRGLAALAQNTPAPDLIRG
TGTGTGPATGHIAFVFPGQGSQWQGMAAELLASSPVFAARFAECDDALGRLLDWSVTDVI
QGADGAPSLDRIEILQPALFAVHVSLAAAWAAAGVEPAAVVGHSQGEIAAAYVAGALSLE
DAARIVVLRSALFAEELVGKGAVASVALSPDAVEKRLAAWDERLVIAGRNGPSAVTVAGE
VAALEELVADCKADGIRAQVVGSTVASHCAQVDPLRDRILAMFADITPRRGHIPFYSTVT
GGVLDTGELDAEYWFRNARHPVNFEGAVHELLADGFGFFVESSAHPVLVTAMQQMFEDAG
AEAVAVGSLRREEGGARRFLASLAEGHVGGLPVHWPTVFAGAEPHRIDLPTYAFQRRHYW
LESAETTGDAAGLGLESAQHPLLGAVTEFPESGGVLFTSRLSLRTHPWLADHAAAGTVLL
PGAAFVELAVRAGDEVGCGVVEELVIEAPLTLAEGDGARLQVFVGEAGDSGRRTLSVRSR
PEGSGPGAAWTRHATGVLAPAAVTTPPDTGLAQWPPAGAVPVDPERVAETYEDMAAAGYG
YGPTFRGLRAVWTRGEEVFAEVALVEDQGLSADGFGLHPVLLDSAMHAIAFRGPGAAGAT
LALPFAYRDVALHAAGASALRVRITPNGPEEVALQLADTGGAAVAAVGSVVSRPVATELL
DTGTSPTRERMFRVGWDELPAPAADTTPDTPHPVPVATAEDIRELAETADLGVPEALLLD
LTGDGQEPSASGVREATGRVLELLRTWLAAPELEDTRLLVLTHGAVAVHHDRELTDPTAA
AVCGLLRSAQAENPGRITLADTDRSQASLALLPSVFTGGEPQLALRDGIRYARRLTRADT
TGALALPAGAAAWRLEPGTDGTLEGLALRPAPAALEPLAAGQVRIEVRAAGLNFLDVLVA
LDMNRVDATIGNEGSGVVTEIGPGVAGLTVGDRVMGLFPDAVGPVAVADHRTVVRIPHGW
SFQQAATVPMAFLTAYYGLRDLAGLRSGESVLIHAAAGGVGMAAAQLARHWGAEVFATAA
PAKWDAVRATGIGEYRLGNSRTLDFEPRFLDATRGRGVDVVLDSLAGEFVDASLRLLPRG
GRFLEMGKTDLRSPEEVAATHPGVSYQAFSLYEAGNDRIGEMLRELVELFDRGALHPLPL
NTWDVRHARAAFRYMSQGRHIGKNVFTLPRTLDTDGTVLVTGGTGSLGRLVARRMVTEHG
MRHVVLAGRRGRAAAGIPELEEELGALGATVHTVACDLADRDAVAALLGSIPQDAPLTAV
VHTAGLLDDGVITTLTPERLDAVFRPKVDAVLNLHELTRDLDLAAFVLFSSGAGTFDSPG
QGNYSAANAFLDALARHRHTSGLPATSLAWGLWGQVTDMSAHLDDSDQRRMATGGMLGLS
VPEGMELFDTALRGPDTVLVPAHMDFAALRALAGSGSLPALLRVLVRTPRRAVDNAAADT
DDLVSSLSRATTGQQEKILLDLVQQEAAAVLGHASADLIEPNQPFKDIGFDSLTAVELRN
RLSRRAGVRLPATLIFDHPAPAPLARHLLGQLGQEVDISEVLMAELDTMAATLAEAAPDA
TTHATVLARLQLLVEQWETTAGATTTDEEEFDVDTATDEAMFELIDREFGTS
>A0A2K8QY32|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MDNEKKLRDYLKRATGHLRAAHRRIQDLQTPEPIAIVAMNCRYAGDIRSPEDLWETVAEG
RDGMADFPSDRGWDLPNLFDPDPDREGRTYARQGGFLQEADQFDPVFFGISPREALTMDP
QQRLLLEVVWETFERAGIDPGTLRGTDTGIFMGATDFDYARDLTELPEGLEGQMSIGASG
AILSGRVAYTLGLEGPAVTVDTMCSSSLVALHMACQALRQGDCSMALTGGTTVMSTPSGF
IEFSRQRALSASSRCQAFSSTADGTAWGEGVGVLLLERLSDARRNGHTVLAVIRGSAINQ
DGASNGLTAPNGRAQQRVIRQALANATLSGADVDVVEAHGTGTSLGDPIEANALLATYGR
NRPADRPLWLGSLKSNIGHTAAASGVGGVIKMVQAIRHGVLPQTLHVQEPSPNVDWSSGA
VELLTQARPWPETGRVRRAGVSAFGASGTNAHAIIEQAPEATRPASTPAEGVTPVGGGAV
PWVLSAKTESGLRGQAERLLARLAEGAEPSPADVGFSLATTRARFDRRAVVVGGSLEDFR
AGLTALTRAEPGGLVTQGMAGPVGKPVFVFPGQGSQWVGMAVGLLDSSPVFAGRIAECEA
ALGPFVDWSLVDVLGDEAALGRVDVVQPVLWAVMVSLAEVWRSCGVVPAAVVGHSQGEIA
AAVVAGGLSLEDGARVVALRSQAIARGLAGRGGMMSVAESADRVRERIAAWDGRISVAAV
NGPGSIVVSGDPEALRELQAECEAEEVRAKLIPVDYASHSAHAEALREELLDLLAPIRPR
TSDITFHSTVTGAPLDTAGLDAGYWYTNLRETVELESAVRALSAAGFGTFLEMSPHPVLT
MPLQATVEDAVVVGSLRRDEGGPERFLASLGEAFVRGVAVDWAAVFTGTGASVVELPTYA
FQRQRYWLERPPARAAASGGDPVDAEFWDAVEREDLTALTAALEVDADEERSSLRTVLPA
LSSWRRGRRERSVLDSWRYHVNWNRVPDPASAALTGTWLLAVPAGHLVGHDVEHSVGHPV
GHPGTELIDAVRDGLETHGATVVTVEVAEADRAAVAARLAEATAGAAPSGVLSLLGLPDA
PHPGHAGVPMGLALTLALVQALGDTGVAAPLWLATRGGVSVGGTDALDSPAQAAVWGLGR
VAALEHPQRWGGMIDLPDTVDGRVTTRLCGALAGRLGDEDQLALRPSGVFVRRLVRAAEH
RGNGPVWTPGGTVLLTGGTGGVGAQIARRLAQAGAEHLVLTSRRGPEAPGADKLRAELTE
LGAKVTVAACDVADRAALEALVREVEAEGPPIRSVLHIAGAGVLVPLADTDLAEFADTAE
AKVAGAANLDALFDRDTLDSFVLFSSISAVWGSGEHGAYAAANAYLDGLAEHRRARGLTA
TSVVWGIWSPEEGGMAANLAEEQLRGRGIPFMSPRLAIDAFWQVMERDETVVVVADVDWE
RFVPVFTSARPSPLIDQVPEVARILAADAGTGADPTGESSSLRDRLAEMAPADRQVAVLS
LVRSQIAAVLGYPGPEAVDASRAFRELGFDSLSAVDLRNRLGTATGLRFPVTVVFDYPSA
EELAGHIGAELFPDDTAATALDPEEADVRRALTSIPLLRLRESGLLDELLRLAGSHDPAT
GPADEEPAESIDDLDVDDLVRMAYDKNDL
>A0A445NHK3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces netropsis|TrEMBL
MDNEQKLRDYLKRATADLRRTRQRVQDLEAASQEPIAIIGMTCRYPGGVAGPEDLWRMVE
AGGNGITDFPTDRGWDPEALAASQTNSGGFLHDAAEFDTGFFGISPREAVAMDPQQRVLL
ESSWEAFERAGIDPTSIRGTRTGVFMGAMAQDYRVGPADGVEGFQLTGNTGSVLSGRISY
VFGAVGPAVTVDTACSSSLVALHLAAQALRAGECSLALAGGVTVMASPTTFVEFSRQGGL
SADGRCRSFADSADGTGWAEGVGVLVLERLSDAQRNGHEILAVVRGSAVNQDGASNGLTA
PNGPSQQAVIQQALVNARLSADEVDVVEAHGTGTTLGDPVEAQALLATYGRGRDESRPLL
LGSVKSNISHTQAAAGVAGVIKMVMAMRHGVLPRTLLVDAPSSHVDWSEGAVRLLTENTA
WPETGRPMRAAVSSFGISGTNAHTIVEQAPEPEPANETEGPADVTVAPGVVPVMLSGRTR
EALRAQAGRLLSALTADPRPGVLDTAYSLATSRAGLEHRAVLVAAGHDDVIAGLTALAED
RPAPGCVQGTTRGEGKLAFLFSGQGSQRLGMGRELYERFPVFAAALDEALAALDLHLDGS
LRDVMWGEREEELERTRWAQPALFAVEVALFRLTRSWGVKPDFLAGHSIGEVVAAHVAGV
LSLSDAAALVAARGRLMQALPAGGAMVAVQATEDEIQPLLADHTDRVSVAAVNGPGAVVI
AGAEDALAFVVARLEADGRKTKRLRVSHAFHSPLMEPMLDEFRAAVSGLTLQAPLMPFVS
NVTGEPVTVAQVTSTDYWVDHVRRAVRFADGVDWLRDHGVTTFLELGPDGVLAAMAQSCL
DEAGADDRAALPLLRAGRPEAQAATTGLAGLHTRGVPVTWGAYFEGTGARRVDLPTYAFQ
RRRYWPKDNPGQSGDLRAAGLGVAHHPLLSAAVSLADSDGALLTGRLSLRSHPWLADHAV
RGTVLLPGTAFLELAIRAGDEVGCDRVEELTLAAPLTLPEQGGIQVQLWIGSPDESGRRT
LNVYSRPDGADELPWTQHATGVLTAGEHRVPFDATVWPPAGAEPVALDGHYDRLAEDGFG
YGTTFQGLRAAWRLGGEVFAEVSLPEGGEADAGAFGLHPALLDSALHAAGFTDLGAQGQG
GLPFSWEGVSLHATGATALRVRLAPAGEGTVSIAVADTSGEPVASVDSLVLRPVSEQRLG
DAGAARDALFRLDWAPVRAEAAAPESVALVGSDALGLAGALPGAVLHQDLASLTAADAAI
PAVVLIPAAGETGDQTIGSAHALVARTLRHLQDWLADERFVGSRLVFVTRGALGGGDPAA
AAVWGLVRSAQTENPGCFGLLDLETETGNDASAAALTRALASDEPQLAVRAGELKAARLA
RVPVSDAVSGAAVWDAEGRVLVTGGTSGLGAVVARHLVTEHGVRRLLLVSRRGPAADGVP
DLVAELAELGAEAVVAACDIADREALADLLDRHPVTAVVHAAGVLDDGVIASLTPERVDA
VLRPKADAVWNLHELTRDADLTAFVVFSSVAGTFGGAGQGNYAAGNAFLDALVQRRREEG
LPGVSLVWGPWDQSGGMTGTLTEADLQRLARAGMPALSAEQGLALFDAALATDEPVVLPV
RLDLPAFRASGDVPPLLRGLIRTRARRAAVAGSSTATGLVQRLGRLADADRDEALLDLVR
GQVALVLGHADAEEIDVARPFRDLGFDSLTAVELRNRLNTVTGLRLPATLVFDYPSVRTL
AGYVLDELLGSEAAVTAPAARAVDTDDPIVIVGMACRYPGGVTSPEDLWRLVTEGTDAVS
GFPANRGWDVDGLYHPDPDHPGTAYTRSGGFLHDAGEFDPAFFGMSPREALATDSQQRLL
LEASWEAVERAGIDPVSLRGSQTGVFAGVMYSDYSAVLAGGDFEGFQGSGTSPSLVSGRV
SYTFGLEGPAVTVDTACSSSLVTLHLAAQALRAGECSLALAGGVTVMSTPSVFVEFSKQR
GLSADGRCKAFSDAADGVGWSEGVGVLVVERLSDARRNGHPVLAVVRGSAINQDGASNGL
TAPNGPSQQRVIRQALANGGLTPADVDAVEAHGTGTTLGDPIEAQALLAAYGRDRDADRP
LLLGSVKSNIGHTQAAAGVAGVIKMIMAMRHGVLPRTLHVDAPSSKVDWTEGAVELLTEQ
TAWPETGRPRRAGISSFGISGTNVHTIIEQPPAPAPERTAPAAPNATAVVPWLISGRTRD
ALRAQAARLRSYVEARPELDPADIAHSLLTTRSRFDQRAAAVAGDRDALLRALAALAADR
PDAHLVEGEAAHPGRTAFLFAGQGAQRLGMGRELYERFPVFAEALDAVLTELAPRLEAHL
DRPLREVLFAAADSADAALLDRTGWTQPALFAVEVALFRLVASWGVAPDYVTGHSIGEIA
AAHVAGVLTLTDACALVAARAGLMEALPAGGAMVAVQATEEEVLPLLTDGVSIAAVNGPA
SVVVAGDEDAARDIADRLAAEGRKTRRLRVSHAFHSPRMDAMLDDFRRVAESLTYAAPAI
PLVSNLTGRLATEEELRSPDYWTRHVRGAVRFADGVRTLRDAGVSTFVELGPDGVLSAMA
QDTLGDEHGALLVPVLRADRPEEQTVTAALARLQVHGVSVDWSAFFAGSGARRVDLPTYA
FQREFYWPQGPSPVTVTADASADPAHQRLWAAVERGDADELAAILGLADEQVSSLGSLLP
ALSSWRQGNQEKALLDTWRYRVEWTRLRGAAAPAADGSWLLVTTDVTDGALHDDLLAALN
AHGTQARSLVLDDACADRGVLAERLTALEDAEGLTGVLSLLPLDERPSTACPPLTTGLAL
TVALTQALGDSGLGARLWTATRGAVSTGPADPVTRPAQAAAWGLGRVAALEYPRGWGGLV
DLPEVLDKHAVQRLLGVLAGLDGEDQVAVRASGLSGRRLARAVVQDLPAETAFTARGTVL
ITGGTGALGADVARWLARSGAENLVLTSRRGPDAPGADALRAELQALGSRVEIVACDVAD
RDALAAVLAGVPEELPLTGVVHTAGVGQAAPLEQTPVAAFAELMSAKAAGAANLHALLGD
RELDLFVLFGSIAGVWGSGGQSAYGAANAYLDALAEHRRAHGLAATCVAWGPWAEAGMAV
DDAISDSLVRQGLGFLTPRSAMTELRRAVVQGDVTVTVADVDWERYFPLFAAMRPSALLA
DLPEIRDLRLSTEHETGAASEYAARLRALGAEERKRLLVDLVRDEAAAVLGHDSADSVPG
QRAFREAGFDSLTAVELRKRLGTVTGLTLPATMVFDYPTPLALARYLGAEILGAGIDVAG
PVATSAAADDEPIAIIGMSCRYPGGVTSPEQLWRLVADGVDAISEFPANRGWDTTGLYDP
DPDRAGTTYTTQGGFLHEAGEFDPGFFGISPREALGMDPQQRLLLETTWEAVERAGIDPA
SLRSSLTGTFIGSSYQEYGRGGAEPGSEGHMVTGSQPSVLSGRVSYVFGLEGPAVTVDTA
CSSSLVALHLACQSLRNGETTLAVAGGVTVMTTTDPFVAFSRQRALATDGRSKAFAEEAD
GFALAEGVGILLVERLSDARRNGHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRQAL
ANARLTPSDVDAVEAHGTGTPLGDPIEAQALQVTYGRDRDADRPLLLGSVKSNIGHTQSA
SGVAGVIKMVMAMRHGLLPKSLHSDNASSHVDWSAGAVELLTEPAAWPAGERPRRCAVSS
FGISGTNAHAVLEEAPRDGEPAAEEPAAPAADSDVLLPWVVSARSAPAVRDQAASLASAV
EAEPGWRPADVAFSLTSARSLFEHRAVVVGTDREELLTGLRAVAADASSPAVVRGAADVD
GKTVFVFPGQGSQWVGMGARLLAESPVFAERIAQCADALSPFVDWSLTDVLRQAPDAPSL
ERVDVVQPASFAMMVSLAALWQEHGVRPDAVVGHSQGEIAAAVVSGALSLEDGARVVALR
SQAIGRRLAGRGGMMSVALPVAEVEERLGGFAGRVSVAAVNGPRSVVVSGDPEGLDELTA
RLTDEGVRVRRIAVDYASHSAQVEDLHEELLSELGPIRPRESDVPFLSTVTGAWLDTSGM
DAEYWHRNLRNTVEFEAAVQSLLGTNHRVFVEVSSHPVLTVGVQDMLDDATGQGLVTGTL
RRDEGGLRRFLTSLAEVFVRGTDVAWPVDLTAAGARRVDLPTYAFQHEHLWIVPSETDRT
ATTDPADDAFWAAVEQQDVSALTSSLHIDEKSLAAVLPGLSSWRRQRREQSALDAWRYRV
AWSPLSGVPQVSLSGTWLVVTAEGIADDDVVAALSGQGAAVRRLVLDESCVDRAVLAARL
RDAGDVTGIVSVLAAAEQPCAAHPALASGLALTVALVQALGDAGIDAPLWCVTRGAVSTG
RSDLVTNPVQAQVQGVGWTAALEHPQRWGGMIDLPGTLDERAGQRLAAALAGTTGEDQLA
IRPSGVFTRRVLPAPAGEPNPDRAWSPRGTTLITGGTGTLGPHIARWLAGQGAERLVLVS
RSGMNAPGAAELVAELAEQGAEASVVACDITDRDALAELIAGLKADGHTIRTAIHTAAVI
ELHSLAETTMEAFAKVVHAKVAGAQNLDELLDDAELDAFVLFSSAAGMWGSGQHAAYVAG
NAFVSALAENRRARGVTATSLHWGIWADDLGLGRVDPDQIRGSGLEFMDARLALAGMRRA
LDDDETVLAIAGVAWDTYHPVFTSGRPTTLFDEVPEVRRLAEAAERSVRKGGEGEFAARL
RALPAVEQERQLLELVRSEAAGVLGYTSAEALSDQRAFRDVGFDSLTAVGLRNRLREITG
LRLPTTMVFDYPTPLALVEFLRAEIAGTDIAAAAPAASAALTNEPIAIVGMSCRYPGGVG
SAQALWDLVMNGTDAVSGFPADRGWDAEGLYDPDPDSHGKTYSVQGGFLRDVADFDASFF
GISPREALAMDPQQRLLLETAWEALEGAGIDPDSLRGSSTGTFIGASYQDYGTGAANATE
GSEGHMVTGTLSSILSGRVSYLFGFEGPAVTLDTACSSSLVAMHLACQSLRNGESSLALA
GGVSIMATPNAFIGFSRQRALAVDGRCKAYSDDADGMTLAEGVGLVLLERLSDARRNGHE
ILAVVRASAINQDGASNGLTAPNGPSQQRVIRQALANGGLTPADVDAVDGHGTGTALGDP
IEAQALLATYGQDRERPLLLGSVKTNIGHTQMASGVASVIKMVMALREGVLPRTLHAETP
SSHVDWSAGAIELLTEPAAWPETGRARRAGVSSFGLSGTNVHTILEQAPLADEPAAPASG
PAPGIVPLTLSAKSDTALRAQADRLLSLLAERPGLHLTDLAFSLATSRTAFDRRAGVVAG
EREELLRGLAALRDGTTAPGVRTGTAGRGRLAFLFTGQGSQRPGMGRELYERYPVFADAL
DAVIARMDTALDRPLREVVFAGDGTPEAELLDATGYAQPALFAVEVALFRLVESWGIRPD
YLAGHSIGELAAAHVAGVLSLEDACALVAARGRLMQALPAGGAMAAVQATEDEVLPLLAD
HTDRVSLAAVNGPSSLVVSGDEDIVVDLAARFEADGRKTRLLRVSHAFHSPLMDAMLDDF
RRVAEGVTYHAPAIPFVSNTTGRLATAEQVCSPAYWVRHVRDAVRFADGVNWLAEHGVRT
FLELGPDGVLCGMARESLADDPHTVLVPLLRRGRPEESALTAALVDAHVHGVSVDWSGFF
AGSGARRVELPTYAFQRERFWPEVVAAPVAGSVDPVDAEFWSAVEREDLGSLADSLELDG
ETVTAMVPALSSWRRRRREQSVADAWRYRVTWKPLTAPATAAPRGTWLLLVPAGSETDPW
TGALTDGLGVETVRVEVTAPDRTALTGRLRELLDAGARFEGVLSLLALTDDEAAGHPGVP
AALALTATAVQAAGDAGLDAPLWCVTRGAVSVGRSEHLQDPAQAAVWGLGRVAALENPQR
WGGLLDLPEQLDAHTARRIAGVLARTDGEDQVAVRASGVFVRRLAHSPAADRPVRRVFAP
TGTVLITGGTGGLGGHVARWLARSGAQHLLLTSRRGPDAPGADALRAELEQLGADVTVTA
CDAADRDALAAVLAGVPAGRPLTAVIHTAGVVEDGVLADLTPENFSAVMNAKAVSARNLH
ELTQDTALSAFVLFSSTAGTLGAAGQGNYAAANAYLDALAEHRRAAGLTATSLAWGPWAQ
SGMVAVDADVESRVRRGGFAPLAPERAVAALKQAIEHDDTVVALADIDWSRYAATVAAVR
PAPFVADLPEMRRATTTGTAADPATGGEPALRSRLAELPEADRGRFLVDLLRTQVAAVLG
HTDASRVESDRAFKDLGFDSLTALELRNGLAAATGLSLPASLVYDHPTLLELSRFLLAEI
AGTLPAAVATAPAARPADDDPIAIVGIGCRFPGGVSSPEDLWRLLADGRDGISAFPADRG
WDLGALAAGASATAEGGFLTGVADFDAAFFGISPREALAMDPQQRLLLETTWEALERAGI
DPASLRGSRTGVFVGTNGQDYPTLLRRSASDVQGYVATGNTASVMSGRLSYTLGLEGPAV
TVDTACSASLVATHWAAGALRSGECELALVGGASVMSGPDSFVEFSTQGGLAPDGRCKAF
ADGADGTAWSEGVGILVLERLSDAVRNGHEVRALVRGTAVNQDGASNGLTAPNGPAQQQV
IRQALADAGLTAADVDAVEAHGTGTTLGDPIEAQALLATYGQDRERPLLLGAVKSNIGHT
QAAAGMAGVIKMVLAMRHGTLPKTLHIDAPSSHVDWSAGAVELLTEPAEWPETGQPRRAG
VSAFGVSGTNAHVIVEQAPPAQAAPEAGPVPASAPAVVPWVVSGRTREALDEQIERLTSF
AAGHPELSPVDVGYSLASGRSAFGHRAVLLAGADGVTEAARGPRAATGTSAFLFSGQGSQ
RTGMGRELYERFPVFAEALDAVLAHLDLELDRPLREVLFAEAGSDEAELLDRTGFTQPAL
FAVEVALYRLVESWGITPDFVGGHSIGEITAAHVAGVFSLEDACRLVAARATLMQALPAG
GAMLAVEATEDEVTPLLADGVTIAAVNGPNAVVVSGAEEAVLETAGRFAADGRRTTRLRV
SHAFHSPLMDPMLGAFRAVADGLTYTAPRIPVVSNLTGALADAEQLCTADYWVRHVREAV
RFADGVHTLRAAGAVTFLELGPDGVLSALVRRALDGQEPEPAVVPVLRGDRGEERAVVTA
AARLHVHGVSVDWPALFEGSGARRVELPTYAFQRERFWPEAIAAPVAGSVDPVDAEFWSA
VEREDLGSLADSLELDGETVTAMVPALSSWRRRRREQSVADAWRYRVTWKPLTAPATSQG
RRLVILPAGYADDAWLTTAVTALGEDTVRVEADLTDRAALTDRLTAIQESDGAYTAVVSL
LAATTGDTSLPAPAAWPAELLEALDAAGIEAPLWCVTRGAVSVGRSEPLVNTGQAAVWGQ
GRVAALEHPDRWGGLADLPETLDARTGDRFATALGGHDGEDQLAIRPSGVFARRLVRAGR
SSSTAWTPSGTVLVTGGTGVMGGDIARWLARHGAEHLVLTGRDGERAPGTADLQAELTGL
GATVTIAACDLTGAFGRATLTDLLDALPEGTPLTAVVHADEETGTDAAAALAGVTTLDAA
LGDRPLDAFVLFSSIAGVWGVRGQGEGAAACALLDAFATRRRARGATALTVSWGAWATTT
DPGMTGHLRLIGLPVLDTEAALAALAHAVTDDDSGITLADVRWETFAPATTATRRTALFA
ELPEARTAVEALTRGSRDGQSAADTLRERLRALPESERSAELLDVVRDKVAVVLGHASAD
AVDADLPFRDLGFDSLTAVDLRGQLTTATGLSLPATLAFDHPTPAVLADHLKAELLGELT
GAPGTTADALPTGHPADDPVVIVGMACRYPGGVRSPEDLWRLVMAETDAVGELPTDRGWD
LDDLLSGGPGGRGRSATGHGGFLYDAAEFDPGFFGISPREALVMDPQQRIVLEAAWEALE
RAGIDPVTLRGTDAGVFVGGGSGDYRPPVEFGEWQTAQSASLLSGRLAYSFGLNGPTVSV
DTACSSSLVALHLAAQALRNGECSLAVAGGVTVMATPTGFIEFSAQGALSADGRCKAFSD
AADGTGWSEGVGMLVIERLSDARRNGHQVLAVLRGSAINQDGASNGLTAPSGPAQQRVIR
RALAAAGLSTTDVDAAEAHGTGTKLGDPIEAQALLATYGQDRERPLLLGSLKSNIGHTQA
AAGVAGVIKMILAMRHGTLPKTLHADTPTTHVDWTAGAVRLLTETTDWPDAGHPRRAAVS
AFGASGTNAHVILEQAPAAEPAAAPAGPVRDTGTLPVLVSGKTPGALRAQARRLLDHATA
SPDATVGDLAYALATTRTAFEHRAAVLATGRDTLLDGLTALAAGDLAPHVLEGEAGRTGR
TAFLFSGQGSQRLGMGRELYERFPVFADALDEVLAHLDVSLDRPLREVMWGEDARALDNT
GYAQPALFAIEVALFRLVESWGIRPQFVGGHSIGEVAAAHAAGVFSLADACRLVTARAGL
MRALPTGGAMVSLRATEDEVTPLLTDEVAIAAVNGPNAVVVSGTEEAVLLIAGHFTDLGR
KATRLPVSHAFHSPLMDPMLDGFRRVAEELTYHKPVVPVVSNLTGEMSTGEDLCTPEYWV
RHVREAVRFADGVRALTGRGVTTLLELGPDGVLSALARESAPETTLAVPVLRKGHSEETT
LVTALARLHLGGVAPDWSAFYAGTGARRAELPTYAFEHARFWPDDRPAASQVAADAGDRE
FWDAVEREDFASLETVLSVGGDTLSKVLPALLDWRRARQEQSVVDGWRHRIVWKPLTGTR
GGRPAGTWLAVVPAGPEDDAWTTEALAALGTDVVRLDVADTADRPALAGQLRDLAAGGTP
FAGVVSLLALRETAEGSAPTGLALTTALLQALGDAAIGAPLWCVTRGAVSVGRAEALRSP
LQAAVWGLGRVAALEHPERWGGLVDLPEVLDERSATGFAAVLAGSDGEDQVAVRPAAVFG
RRLVQAPGKASGPQWDPSGTVLITGGTGALGGHVARRLARDGVRHLVLTSRRGEDAPGAR
ALRDELLALGVRVTVAACDVADRTALEAVLADIPAEHPLTGVVHAAGVLDDGILDRLTPD
RFEAVFRSKVTSAFLLDELTRELDLSVFVLFSSASAAVGNPGQANYAAANAVLDALAEHR
RAHGFPATSIAWGAWGGGGMADGAAADAAAQRAGIGAMDPELALEAMRRLVMETEPTAVV
ADVAPERFALAFSAARPAALLRELPGYQAAIAATTPQDGGGTADGGLRDRLAGLPHSRRH
EAVLDLVRTRAAHVLGHPDRDAVGAERSFRDLGVDSLGAVELRNQLNAASGLGLSATLVF
DHPTPAALAGHMLRQLVPDENGPTDTTDDEEAEIRSLLSSVSLAQLRDIGVLEPLLQLAG
RGTADPAPEDGDEESIDSMALDDLVRAALDNQSDASRD
>A0A5B7URN0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MENEGRLRNYLKQAVGELQDTRERLQELERAASEPIAIVGMACRYPGGVVSPDGLWDLVT
EGRDAVGAFPADRGWDVEGRYDPNPGVPGTYYARGGGFLYEAAEFDAEFFGISPREALAM
DPQQRLLLETSWEALERTGVDPQTLRGSDTGVFVGLMGHGGQRYGLGAEESGQGGEGFGG
TGSAASVASGRIAYLLGLEGPALTVDTACSSSLVTMHLAARALRGGECSLALAGGAAVMA
TLDTFVEFSRQRGLAEDGRCKAFSAAADGTGWSEGAGMVVLERLSDAQRLGHRVLAVIRG
SAVNSDGASNGLTAPNGPSQQRVIRQALADAGLTAADVDVVDAHGTGTRLGDPIEAQALL
ATYGQERPADRPLWLGSLKSNIGHTQAAAGVGGVIKMTQALRHGVLPRTLHADEPSPAVD
WESGAVELLTEARDWPENDRPRRAAVSAFGISGTNAHLIIEQAPEPSAGAGPEAGAETPR
PAGAALPLLLSASSPAALAARAQQLHALAPAAAGGPLAVALATRAPRLPQRAAVTGDDPA
AGLLALAEGRPSRDVLTGVARPRGKTVFVFPGQGSQWSGMALDLYRDSDVFRAQLDACAA
ALEPYTDWNLLDALAGPLDRVDVVQPALWAVMISVAALWRHHGVTPDAVLGHSQGEIAAA
YVAGALSLEDSAAVVALRSKAITRLAGTGGMASVQLAQDETERRIEAYGGSVEVAAVNGP
GSTVVSGRPEDLAELVASCEADGVRARLVPVDYASHSAHVEALREEILSALSGITPGPSR
VPFHSTVTNEAVAGPELDAAYWYGNLRRTVGFAQGTRALLDQGHAVFVEVSAHPVLVNAI
GETVEEAAADAVVLESLRRDDGGRARFHTALAKAYVHGVEVDWRIPPGAATAAELPTYPF
QRSRYWLEEPAAVGDTSALGLRRAEHPLLGAALRTADADTLVLTGRLSRGAQPWLSDHGL
GTSVLLPGTALVELALHAGDQVGCGHLAELTLHAPVVLDADLDLQVLIGAESGDGRPVSV
HTTLAGTDDWIRNATGRLTNESHPAPDALTAWPPPGAAAVPLDGFYETLAERGYAYGPAF
QGLRAAWRDGDALYASVALPDEQDVTGFGLHPALLDASLHAAGLSGADGVRAPFSWSDVR
LHATGARAARVRLTPAGPDAVAVLVTDEAGQAVASVGELALRPVDVAALGHRRADTSALF
ALDLVPVDLPEPPAERTWIELGADGGDRPAAPVSATAALWTCPEGEVEDVVDRTLHVVRE
WLAEPHLTDVPLVVLTRADDLAHRAVTGLLRTARGEHPGRLRHIDIDGHPLARAALPAAM
AADHPELALRGATAAVPRLTRAAASPALPEPAERPWRLGLTYRGDLDSLSLTPCPEVLRP
LEPGEVRVAVRAGGLNFKAVLLELGMVARDEWSSLGEGAGIVLEVGADVTGLTAGDRVMG
LFTGGLGTVTVTDRRLVVPMPERLTFAQAAGVPVVYLTAYYGLADLAGLTAGESLLLHAA
TGGMGFASLQLARHWGAEVFGTASSGKRDVLRAWGFDDDHLADSRSLGYAEHFAKATGGR
GVDVVLNSLAHEHVEESLALLPRGGRFVEMGKTDIRDADEIAAAHPGVRYRAFDVMEAGF
DRIAEMLEEIRVLFDEGALRPMPLTTYPVHRAPEAFRYLSQARHVGKIVLTLPAPLDPDG
TVLVTGGTGVLGGLVARHLVAEHGVRRLLLTSRRGPAADGVDALVADLRAAGAEVSVVAC
DVSDRESVAGLVRSAHRLTGVVHAAGVLSDGVLEALTREDLDAVLRTKARSAQYLHELTQ
DHDLALFALFSSVAGVLGSAGQGGYAAANAYLDGLVEHRRGLGLPGTSIAWGLWARESAM
TGHLSEGDKDRLARMGLGAIDDEQGLALFDAALGLHRPLAVAVPVDVARLRESGQPVPEL
LSALDPAARVRRRVVARAAATTQADRLVELPERQRRKELLELVRESAAVVLGHSTAESVD
EDSAFKDLGFDSLTAVELRNRLGTATALRLPPTVVFDHPTPAGLAAFLDGLLVPAQETTV
GSLVTELDRLAVADLDEDERDVLAKRLQEVLRRLAAPAEAGGEERDFTEASDDEIFDFID
GELDIA
>A0A5B7URM0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MTKPATQDLRTGAVTGTVPWVLSGRSTAGLRAQAGRLLARLAPGPAAGAAEAEAGLLAEV
GRSLVAAGAAGEYRAVVIGRDRAELLDGVRALAEDRPAPHVISGRAPRQAGPGTRPVFVF
PGQGTQWAGMAVALLDASPVFAEAVRDCEKALSPYLNWSLEDVLRGVPGTPPLDQVDVVQ
PVLFSMMVSLARLWRRFGVEPGAAVGHSQGEIAAAHVAGALSLDDAARIVALRSQALTKI
RGRGEMLTVLAPGDQVRTMLADWEGALSVAAVNGPATITVSGDAAAMADFGAALRAARMM
RWRVPGVDFAAHSPHVEDLRETLLDLAASVEPAAGDVPFYSTVTGRRVDTEGLDAEYWYR
NLRQTVRFDDAVRSLVADGHEVFVECSAQPVLTVGMQDIVEELGRSAVLMATLRNEDGGA
ARFLAALAEAYVHGVAVDWTAAFA
>A0A5B7UM17|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MENEDKLRYFLKRVTGDLRETRRRLREVEAGEQEPIAIIGMSCRYPGDVRSPEDLWQLVA
EGRDGVTPFPADRGWGDVELSDPEDPDRVFRTEGGFLHDAGDFDPGVFGISPREALAMDP
QQRLLLETSWEAFERAGIDASSLRGSRTGVFAGVMYHDYTARLRSVPEGLEGFLGTGGLG
SVASGRVSYTFALEGPAVTVDTACSSSLVTLHLAAQALRSGECTLALAGGVTVMTTPHTF
VGFSKQRGLAADGRCKSFSDDADGTGWGEGAGMLLLERLSDARRNGHRVLAVVRGSAVNQ
DGASNGLTAPNGPSQQRVIRQALDSAGLTAAQVDAVEAHGTGTTLGDPIEAQALLATYGQ
ERPAGQPLWLGSVKSNIGHTQAAAGVAGVIKMVMALRHGVLPPTLHVGERSRHVDWSEGA
VELLTDARPWPQTGQPRRTAVSSFGISGTNAHVVLEQAPAEDADDAVEEPVEPVLTEAVP
WVLSGNDPVALRERAAALLRHLDGRDDRAVDVGHALALSRTALEHRAAVVGTDRAELLRG
VEALATGGEAPHLVRGTVGTRGRLAFLFSGQGSQRAGTGRELYGEFPVFARALDEVCAGL
DPHLDRPLREVLFAEPDTQAAALLDLTTYTQPALFAIEVALFRLVTAWGLAPQFLAGHSI
GELAAAHVSGVFSLTDACALVAARGRLMGALPEGGAMLSLRADEPTVRRLLAEHGRGTVD
VAAVNGPESTVVAGDADAVAAIDAAWRESGGKTRYLRVSHAFHSPHVDAVLDDFRAVARN
VTYGTPAIPIVSTLTGAVLAPEQARDPEHWVRHAREAVRFLDGMRCLREQGVANFLELGP
DAVLAAAGRDCVDEGALLVAAARANRPEGTVLTSAVAALHVRGVALDWHAVFAGRDARRV
DLPTYPFQRTRFWLDTGVPAGDMASVGLRPADHPLLGAAVTLADEEGALLTGRLSLATHP
WLADHTVGGVVLVPGAALVELAIRAGDQVGLDLVEELTLAAPLVLPQDGAVRLQVSVGAP
DAAGRRALSAYARADDAPDDQPWTRHAFGTLAAGDRAPAALGATWPPAGAEPLDIAGRYD
DLAAAGLGYGPAFRGLRAAWRRGDEVFVEVELADEDAAGSFGLHPALLDSALHAIGLGHF
VADAERLHLPYSWRGVRLHSSGASVLRGRLSPAGAAGVGITLADGTGAPVASVEALSLRP
LTADALAGDRLDSLFRVDWTRVRPDACAPARRAVLGDGLRLSGEARAYPDLAALADDEVP
GLVFAPVPAAAGPAEATHWALSLARAWLADDRFGAARLVFVTTGAVAAGPDEDVPDLACA
PVWGFVRAAQTEHPGRFALVDADDRSAAVLQELPDEPQLALRGGDWFAPRLVRARPAESP
ESGFGEGAVLVTGASGMLGGLVARHLVVRHGVRRLVLASRRGQVGALYDELTGLGVEVAV
VACDVAERDEVAALLAEHPVTAVVHTAGVLDDGTIGSLTPERIDTVFRPKVDGARHLHEL
TRDLDLSAFVLFSSAAGTFGNPGQGNYAAANAFLDALAQHRRAAGLPATSLAWGLWAGAD
GMGARMAQTGAAGLTPQEGLRLFDAAVALPSAVAVPTRLDLAPLRAHPEAVPALLRALVR
TARPEAAKAAGGLAARISALPEDERLPALLDLVRTSVAAVLGHASAAGVEPERAFDELGF
DSLTAVELRNRLDAATGLRLPATLVFDHPTPQVLAGHLRAELLGGETAGTATLRTAAADD
EPIAIVGMSCRYPGGVRSPEDLWRLVAEGRDAVSDFPDDRGWDVEALYDPDPDHAGTSSV
RSGGFLHDAAEFDPVFFGMSPREALAVDPQQRLLLEASWEAMERAGLDPKALRGSPTGVF
AGVMYNDYASRLRRAPEGFEGQLGVGSSGSVASGRISYVFGLEGPAMTVDTACSSSLVAL
HLAAQALRSGECTLALAGGVTVMASPATFVEFSRQRGLAPDGRCKAFSADADGTGWGEGV
GMLVLERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALANAGLTTS
DVDAVEAHGTGTTLGDPIEAQALLATYGQDRAEDRPLWLGSLKSNIGHTQAASGVAGLIK
MVLALRHGVLPRSLHITEPTPHVDWSSGAVSLVTETTPWPEVARPRRAAVSSFGISGTNA
HAVLEQAPDDIPATPETPADPPSAPVPFVFSARTEDALRAHASQLAVAAEEVASADMADT
LLSRSVFEHRAVVVGGGAEALAAVAQGAESARVAVGVARPAGKVAFVFPGQGSQWLGMGV
ELAKSSPVFRASLDACAQALAPYVDWSLYDVLNDAAALERVDVVQPALWAVMVSLAALWR
SYGVEPDAVVGHSQGEIAAAHVAGALSLADAAKVVALRSKAALVLSGQSGLVSLAVTLDA
ARERIARWQGRITVAAVNGPRSVVVAGGADDLDELLEACATDDVWARRVLIDYASHSPYV
EPVREELATLLAGVEGKAAQVPMLSTVTGEWLTGTEVGAAYWYQNLRNTVRFEEGTRGLL
DRGVGVFVECSPHPVLAFGVRETLEAVDAEAVVVGTLRRTDGDLDRFLLSAAEAYVEGLP
FEWRAAVPAGRPVDLPTYPFQHQRYWLDAPRDLSVEEAAGGLGLAGTGHPLLGAAVELAD
GQGLVCTGRIGTDTHPWLADHAVAQTVLLPGTAFADIALAAGGRLGLDEVEELTLAAPLV
LPERGGVRLRVTVGADDGSGRRALHVDSCPEEPDAADWTRHATGFLTTGAPAAPAALTQW
PPADAARVDLGGLYDGLEEAGFGYGPAFQGLRSAWRGDGAVYAEIALDEDQHRDAASFGL
HPALLDAALHACTLGGLVEDAGRPRLPFTWNGVRWHATGATTARVRLTPAGPDAVSLELA
DAQGQPLATVASLVLRPIAADHWGARHRDALFRLEWVAAPTRAATPAPARGCAVIGPDDL
KARAGLAASGAAVEEHHDLAALAAAGVPGLVLAAFAEDGPDFAEDGPEPVAAARTAAFRA
LRLAQEWLADDRFLDSRLVFVTRGAVAAGPDEDVPDVADAAVWGLIRAAQSENPGRFVLV
DVDGHDASWAALPGILTGAEPQVAVRAGDARAPRLARFGPSAPQSPIAFAPGGTVLVTGA
TGMIGGLVTRRLVTEHGVRHLVLASRRGAAAPGADALCAELAGLGARVTLAACDVTDRAA
LGKLLAEVPADHPLTGVVHSAGVLDDGVLASLTPERIDTVFRPKVDAAWHLHELTRDLDL
SAFVLFSSAAGTFGNPGQGNYAAANAFLDALAQHRRAAGLPATSLAWGLWESASTLTGAM
ADSDVARMSRSGVTGLTEEEGLALFDLGCAAGDAVVVPMRLDAGSLRGGPDEVHALLRGL
ARPRAARAAGAAEEPPARRLAGLTEEEQERELLGLVRDRTAAVLGYAPDELDVSGALTQL
GLDSLTALQLRNELAGATGLRLPTTVVFDQRTGPALAGYLRRELAATAGDAPAAPAALAA
EDTLVGLVRQSYDLGIAKEGWLMVDAAARLRPVFEKADEVAALPPVPLATGPGVPLLCFP
PTMAPSGPHYFSRFAPVFAGQRDVTLLPHPGFGAGEPLPATREAVIRFQADAVERQAGDR
PYVLLGYSSGGWMANAVAALLERQGRAPAAVVLLDTYIATNSFEKRLEAALSERMSTSQA
FDLLTGAQMTGQSGYVRVFEDWKPEPVGAPTLFVHATFPPGETEALETEDAWQPQWPHRH
EDADVPGDHFTIMDVHSESTALAVRAWLDDARFDTLG
>B8MM93|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MEHTMPVSDPPLSACPEPIAIVGMGCRWPGGVENSSQLWDLLKEKRDGWSEFSKDRINVD
GFYHPHGQRPGSMYTRGGHLLQGDSRDFDHSFFGITTTEAMAMDPSQRKLLEVTYEAVEN
AGEPLEKFFGSRTGVFVGNFNNEHQIMQYRDPDHTLPYAVTGGGPTILSNRINYVFNLSG
PSLVVDTACSASMYALHLAVMALRGGDCDAAVVAGANVILGPDNQLFTTKLGAVSPTSRC
HTFDASADGYSRAEGFGAIYLKRLSDAIASEDPIRAVVRGTSFNANGKTGGISHPSAEGQ
EAVIRQAYKAAGGLHPDLTGYAECHGTGTPVGDPIEVSAIGRVFSPGRKDNPLLIGSIKP
NLGHSEAASAMSQIMKAVLAMEHGEIPPTIHIKNFNPAIDFETARAKVVTEMTPWPTNRL
RRVSINSFGYGGANAHCILDHPSVVIPGYELRGLPYAYEKMSISSPLRTVQSNGEKNGNG
HWNRHNNGRLNNHSNGCANGHPNGHANGHSNSHAEHNGHDTYNGRLPSFTWCQPAKIRQI
EQAGARKFILLTMSAHDEAALKMKLSAVPELLKQYYIADLLYTLACRKSSFSRRAFAIAD
SQTVLDELDSNLVRTGKAPSSPPQRIGFVFTGQGAQWPEMGAKLLNEFSVFRSAIQYLDL
VLSKLQRRPSWSIEGALLEPTASSRIHEPAFSQTVCTAVQIALVSLLKQWDVHPAATVGH
SSGEMAAAYAAGRLKASEAIVLAYFRGQVVSCNQRKGLMMAVGLGLAEVVSFMEGFESGV
KIAAINSPESVTLSGEPEQIQQLNRKLEDKRIFARVLKTGNNAYHSHHMAALGPSYEELV
TQGLKEVSLIIENEPSNPVVRWVSSVTMKEVEGSVLPSYWRRNLESPVLFSSAVEKLAET
NPMDLLIEVGPHPALSGPLKQIRSRLESVGSSLPPCLATLQRGENDVISMLMLAGNLFIN
NVAIDIVAVNATETMVDGGLTLSHGFPCIDMPPYKYTYPETPIHFENRFNKEYRTRKHPR
HDILGTRVPGGSRTHPQWRNVLRLKDLPWLEDHKLLPHAVLPGAAYITMAIEAVSQLHYE
AEDAAPIKCFKLRQVAINSALRVEDTEIGVETVLDMERLPLTNTAAMSRWYKFSVGSIIP
DTDSWTQHCTGLISVSTTEASIDEGQRLLADPRSRSLDIARWHRSFYAAGLEYGPAFQGL
SNLRAFRGSNLASANVALKPTADFANESKYTIHPATLDMCIQLALIACHAGQVENFKNAF
VPIFADDVSIWVPESESDDKALGVASGRILGLRSMYARSQLYSSSGAPLLDMGELKCVSY
DGESDASNSNVAREPYWRPVARVDIDTLMPVAATAMFPPKEVPPSSITALESLSAHILAS
IGEKLQTNIISDRSQNHNSFANWVKSWISSANGEDVQKLGKAERLAMIERLAENLIYIPE
AKCLKALHDNSSKVLGGITNSMKVLLENNLLVELFASGIAVSGAYSQLQNIVDLLGHKNP
QLRILEVGAGTAGATTAVLDTLISNSALKRVQEYVFTDFAGWSITEAQSRLIGHDEVVFK
TLDILQDPVSQGFELHDFDLIIAADCISKLDSAETALRNIHSLLKHSGSLVLLEATRSTL
TSEIFSRTLTGKWDQEQVIMKADKWDDILRRCGFSGVNISLQDYVGDQQMTTVMLSKALE
IKADTHSKELNPSDVYLVYRDSLPLLAESIVKILAEQGINTILTDLFSGHEIPPSSSVIS
LIDINGAILTCRDDAYFKALQAIIPQVSSMVWVAADLTTPSESSIMKGMLRSISAENVLS
KYAFIELDHSYYTPQTRTAELIVQKLNELQTSKPSDVVDLECMLQAGVFYVERLLPEKTF
NEQFRLRHGPQDHVQERHLDTQGPIMARYRQPGVLSSLYFSSDQDFDKPLDNDWIEIKTD
AIGLNMKDLAVATARFDLDKLSTEGAGVVTALGPKVTSVKLGDRVFGIIPGNMGNRLRSP
ASLVSKIPDGMSSDGAASMPVVYLTSIYALKHLARLERGESVLIQSATGGLGMAAIQIAQ
SLGAEIYATVGTDDKVRVLVEEFGIPAHRIFNSRRLSSIDKVMKATSQRGIDVILSSAGG
DSMHEMWRCIAPLGRFIDVGRTDVLGGGRLGLEVFKRNATFSSFDMGLIYRQDPGLVSKL
MTEMIKLIHEGVIGPIKHLTTFCISQLDSALSTFSKGLHIGKFVISFNNPAATLKIARPA
LRVTFDPNAAYLLVGCLGGLGRSLATWMVERGARHLVFLSRSGANNPEVVSFVEQLVAAG
ANPEIIRCDVCDKNALISTVGKTSNIRKVKGVIHAAMVEGDSFFNNATWPQIQSVLAPKV
IGTINLHDATKNLPLEFFLMTSSIVGSVGTASQGAYTAANAFQDSFAKYRLSQSLPATSI
GLGLILEVGSVSSSIGFQQMLQRNATYGVSETEFLQLLEGALCESYKSSEQSLLSKLDPS
SPAQVVTGLEPARFLSYLEGDRVNDLVWYNNARFQAVKQAILDRAQTLASARIDSSHGTS
SITTQLQNASMPVEKLTIARGAITTRIAELLGVAADDIDSGDSISRYGVDSLVAGELRNW
LIKTFNMEITMLQLLNKNTRIEDLVQGAAGVDSKA
>B8MGX9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MLRERSIIFFGDLSLSIHPAFSQLLRSQKEHSLLSNFLNQAKSALQAEATNLSVIERKEL
PSLTDLYSLSESENGNASDHPILSPALLVILQLGQFISWYEEHPERRYPESDSTLIAGIC
VGQISATAISLAKSLTELLPLAVDAVRIAFRLGTLTTTARNDLEASLHEAWAVVIPRDIT
IPTEDVLDGIVKESEILGRKKPYITAYFPKTVTIQGPPSTLRLVSDWLQKTRGSSPSYFA
SEIPIYAPYHAPHLYNQDSVLQILKGLEFVEKTNDTWSFDQTKVISPTTGTFYDVSDRLD
IMKKALHDILLKPIDWEKLCEGCTSFVTSSEPARWTIRPFGPSKAAKNLLYVIHSEANAD
IILDETFVSSSTDQVSTTTKVPIAIIGMSGRFPDSKNPGELWKLLEQGIDCHKVIPADRF
DASLYVSQDRNSRNKSKSPYGCFIENPGMFDPRFFNMSPKEAAQTDPQQRLALVTAYEAL
EMAGYVPNSTPSTQLDRIGTFYGQTTDDYKDLNTSQDIDTYYVSSVIRAFGPGRVSRSNQ
LGGPSVSVDTACSSSAMALNLACTSIWCQECDTAVVGGMLLLGSPEMYAGLSKGHFISET
GPCKTFDDAADGYCRGESVASIVIKRLDAAKADNDNILAVILGAGTNYSAYAASITQPHG
PTQEMLYRKVLNQAGLHPFDIDYVEMHGTGTQLGDAVEMSSVSNVFAPALSKRPADKALL
VGSVKPNIGHGESASGITSLIKALLILREQKVPPHIGIRSGVLNHTFTDLAKRNVHIPLK
ATAFPRNNSRKRRLMVNNFGAAGGNSAFILEEGPAYEGRGVVDSRVDHVISVTAKTASSL
QKNISNLISYLEQNPEVSLSDLSYTTTARRVQHPLRATVIASNIDELKGHLIQLLETKIS
QPDSGKLPGVAFAFTGQGSVYLSLGQQLFQSNSQFRADLTRFDQICQGYEFKPFLPVINR
SAADINNLSPTQTQLALVSVQIALARLWASWGITPNLVIGHSLGEYAALNVSGVLSISDT
LYLVGIRASFLENLCTKNTHSMLAVHATVEDVKSAAGNKLDRLELACVNGPEDIVLSGLV
EDIQELNQHLKLQGFKCTVLKVPFAFHSSQTDPILDSLEKAAQSVRFLKPEIPVVSTLLG
TVVKETSVFGPSYLRRHAREPVNFDGALRKSYLDGLVDNQTVWLEVGPEPICLAMVKSIL
GSEIKAFPTLRKSESPWRTSAKTLSALHSLGFDVTWKEYHRDFEDSQRLLHLPSYAFDEK
NYWIDYKNDWLLHKGTEVVEKKEPPRINSGPATTTVQTLITEQVKDDKVFIVFESDLSEP
KLHALIAGHSLNGLALCPSGVFADMALTVGDYIRRKHQTKLPASSGSNIVDMQIVKPVTV
TVPRVKTPELLRISGTADLQKGIVEVTFGSYSAQSGKADQNAKCIIEFGDTKLWLNHWSR
SAYLIQKRIEDLERGVKTGDVDKLFEKTIYRLFSAVVDYDPRYHGMKEVMINSSELEAVA
LVRLYEGTDAGNFFCSPLWLDNLAQLAGFIMNGVNVVDPRKFVYISHGWGSYQLADDIDA
AKPYHVHVKMHPAEKNVVAGEVSIFQGGTIIGLCSSIKFQKVPRSLMEMLLAPPSHQQQS
NTQVPSQRTTSLSSKQPRVAPERKAVIPEYYSTKSQPGIKSMALETIAQEIGITAVELVD
DATFVELGVDSLMALTILSKLRESLHLDLPSDIFQELTTIGDLRGFLDKFDNANDDEVDT
PSSDSMSPILPTPDDETTIAGDILNTVYSIMAQQIGVEIEELLAVDDLSSLGLDSLMSLS
IQGAIQEALSLKVELQLDGTAKLPTLVNIQEALGLSPTVPLSVPQPRIPATSHRASLGPS
ASTLLLQGNLRSGSRFLFMFPDGSGSPAAYAALPEISPDLVVYGLNSPFLQSADKYDCSI
EEIAHIMLQAVQSIQPHGPYTLAGWSAGGMYAFEAARQLTQAGETVSKLILIDSPCRSTY
EPMPINLLNFLVSSTIFKASNRIVDHFRSTIRALQNYSPTEIDASRAFEVFIIWAEKGLS
EDLKDAERGNVDWSHGVANWLFKREANAGPLGWEKLLPGRPISVTDVAGNHFSMVNALNS
KSLGRSVADAMRDDLRDSKQQWRIF
>G0Q9U1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MSNTSTPADEQKLLDYLRKVTTDLQQTQQRLREAESRDHEPIAVVAMACRFPGGVRDPED
LWRLVSGGGDAISAFPADRGWDLAALHDSDADREGTTYVTQGGFLDGADRFDPGLFGISP
REALAMDPQQRLVLETAWEVFERGGIDPLSLRGQSVGTFVGANPLDYRSGLSTVPEGFEG
HLLTGGAASVVSGRIAYAFGLEGPAVTLDTACSSSLVALHLAVQALRRGECELAVAGGVA
VMSTPAEFVGFSRQRGLSADGRCRAFSEDADGMGLGEGVGLLLVERLADARRNGHEVLAV
VRGSAINQDGASNGLTAPSSPAQARVIEAALEDARLAPDQIDAVEAHGTGTKLGDPIEAQ
ALLATYGRNRPRERPLWIGSLKSNVGHAQAAAGVGGVIKTIQAIRHGVLPRTLHTARLTS
EVDWSDGSVAPLTENLPWPDRDRPRRAGVSAFGMSGTNAHVILEQPDPAESTAPAAAPAA
GTGDEQAATGETASARGRALAWAVSGATEAALRDQAARLHTFLGDRPATDPAAVARSLAT
GRAALDHRAVVVGGSPDALLEGLAALTTTTGGNAAATGAAVATGSVREGAARPVFVFPGQ
GAQWSGMALALADAEPAFAASLRACATALRPHVDWDLLTELGGPLDRVDIVQPASWAVMV
SLAELWRAHGVEPAAVVGHSQGEIAAAVVAGALSLEDGALVVARRSRVIGRSLAGLGGMA
SLALGREDAEERLRPWADRLGVAAVNGSRATVVSGDPDAIAELVAGCEADGVRARVVPVD
YASHSPQVEAVRDELLAELAGITPRSSRVPFHSTVDARALDTTALDAAYWVRNLRGTVEF
AQVTRQLVDAGHTLFVEAAAHPVLSLAIEETAGPDVVTVSSLRREDGGHDRFLTSLGEAF
THGATVDWTPAHPGTGTTPLPTYAFQHKRYWLEPQPVAHSAAPPADRAEARFWEAVERGD
LSAVTETLRLADGAGLPELLPALGAWRRNRHEQATVDAWRYKTAWRPLAPASTAPALAGT
WLLVVPEDHVAVPFVDATLRGLEAAGADAHLLPVAAADADRGKLAARLHEAVGDGRDLTG
VLSLWSLDGSPLPGSPTLSTATLGTLALLQALADTDLTAPLWCVTRGGVATDDITPAEPV
PAELWGMGRVAALENARLWGGLVDLAPDTDDATAVTEITAALRRTDAEDQIAVRGGRPLG
RRMVRDLAADRTPARDYRPRGTVLITGGTGALGKLLARWLARNGAEHLVLTSRRGPDAPG
ADALEAELTGLGVRVTIAGCDIADHDELAALVTRVEADGPPVTAVVHTAAHIDLGPLLET
TVEEFESAYHAKIRGARNLDRVFEGHDLDAFVLYSSIAAFWGSGLHGSYAAANAHLDALA
QQRRARGQTAASLAWGVWRPVDIQESYAAERMAISERAQAQGLPFLEPDLGIEAFRQAVD
HDDVNVALANIEWDRFVSLFTMARPTRLLDDLPEARAALERIAESEKRTTDDAEESHTLR
EKLSALTAEEADRHLLDLVREHAAAALGHDGPGEVLPARAFRDLGFESLTAVELRNRLSR
ATGLRLPAGLVFDHPTPAAVAVLLRAELLDDGPATTEALHAQLDRLETVLARLDTDPADR
APVTARLRALLDRWTADEGAQDDGPASVAEHLESASDEEMFEFIRREFGRS
>G3J038|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Methylobacter tundripaludum (strain ATCC BAA-1195 / DSM 17260 / SV96)|TrEMBL
MSDQEKMAQGEPQGREEAFRQALQKASMTIRQLLEENASLKNKEPVAIIGMACRFPGGAN
NPEQFWQLLQGGIDAVTEVPSNRWTAEDYYAADLQAPGKMYTTRGGFLSTPVDGFDADFF
GISPKEARAMDPQHRLLLEIGWEALEHACLVPSTLKNSRTGVYVGMSSDDYARSHRHSGQ
PENIDAYAITGSTFSTAVGRLSYILGLQGPCMALDTACSSSLVALHLACRSLQSGESDLA
LAGGVNLMLSPELHICFSKLQAISPDGKCKTFDASANGYARGEGCGMVVLKRLKDAVRDG
NRILALVKGSAINQDGKTNGLAAPNGNAQQAVIREALADAGLQPAAVDYVEAHGTGTILG
DPIEVEALGAVLGSGRQDPLRLGAVKTNIGHLEPAAGMAGLIKILLSLAHEELPQNIHFH
RPNPHIDWNNLPLRVLTEKSAWRRSARPRIAGLSSFGFSGTNAHVIVAEAPQAEPQTGEQ
QQDVHLLNLSARDEAALQTLIADYLKVLPQDETENASADLADLCYSAAVGRHHWPWRLSV
AGRSPAEMRRKLADFIQQGQENSDLVTGHNEEGAPDIAFLFTGQGSQYPGMGHALYQSQT
VFKQAIDRCDAVLQPLLNRSLPDLLFNTEAEVLNRTAYAQPALFALEYALYELWSSWGIS
PSVLMGHSVGEYVAAYAAGVFSLEDGLTLIAERGRLMQALPAGGGMAAVFASESLINSAI
APYQGRISIAAYNGPEQLVISGDEDAVRAVCATLDGEGIQTSVLAVSHAFHSQRMEGMLA
DFERVARRVVFSPPRIKLISNITGMTIGENIACAEYWLEHIQRPVDFSAGMATLKNAGIR
LFVEIGPHATLLGLGRRCLPGGGTWLPSLRQNVPEQQQLSRTMAGLYVQGAAVNWSAVYA
NQACRWASVPTYPFQRKRFWVEAPAQQKIIHKPSSSSLAHPLLDRMIRSPLLESILFETR
FGEAELPVLRDHHIFGKTVVSGACLTSMILGAAKQAFGEGTIQLAELMFHQALAIADGAT
RSVHLALKPLGDGTASFRLVSLEADSTTTEGTLHAGGNLRVLPHSAHQSTHPLSSPPELW
HRFDTEIPGQSVYEAHRRRHIELGDSNQWLESVRLGRSEAIGRLRLPSSDGQTLAVDGYL
LHPGLIDSCYGLLGSVVALEDDETLVPFAIERFNLVRPAQGQQFWVHIRRRVLEEFPDKL
IGDIQLLDEQGELIAECLGLEGRAATPDTLLRTLAKDPGQLFYRLDWINRDRQTALPGSA
QNWLIFMDDAGHGSEIAKRLKAQGHSVAAVYPGTCFERLETQGYRIDPMQAADMLSLLTT
VFKQTTYVGIVYLWSLNNHKDNPAALEFTITQSCAPALHLVQALGRIEPAVVPALVLVTQ
GGQPIDLPETSARSVCVDQAPLLGMGKTIALEHPELRCKCIDLDPDDTDESNADFLVQEL
LNPTQENQIVRQGSNRLVARLIRYRPEHTQNLPVRQEGHYLICGGLGGLGLLLANQLVAR
GARHLTLCGRNAANPEAAAVIAGLEQSGASIRVRLTDITDAEQLQALIATASAEQPLTGI
VHAAGMLDDGVLAQFDWPRFSRVLASKTVGLQYLHELSRHLPLDFFIGFSSMASLTGSPA
QGAYVAANSFVDALMHQRRAEGLAGLSINWGPWAEVGMAARLDDRQRLRLSSQGINAMSA
EDAFRTLDRLWPNPPAQIGIMDIHWPEFLRHFPGATDLPLFELLRQRSDTGASTEPEATS
QAQWITQLEQTPVARRRTLLSSLICGEINRVLGAASDRSIAPRQRLFDLGLDSLTAVELK
NRLSAALTCPLITTLLFDYPTLEALTNHLSMIVSISFEAVEVNAPATTSTSDDKAAALDQ
MSQQELEDLLAEKLSLIAE
>G0Q9U0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MTTNEEKLRDYLKRATTDLRQARRRITELEGRDHEPIAIIGMACRYPGDVTSPEDLWRLV
DDGRDAVTGFPTDRGWDLDALYDPELRTPGTSYVREGGFLHDAAAFDGELFGISPREALA
MDPQQRVLLETTWEAVERAAIDAARLKGSDTGVFIGAGHPGYGVTFGQSDLPDGVEGYSM
TGKAASVVTGRISYTFGLEGPAVTVDTACSSSLVALHLAVTALRKGECSLAVAGGVTVMP
TPELFAEFSRQRGLATDGRCKAFAASADGTGWAEGVGVLLVERLSDARRNGHQVLAVVRG
SAVNQDGASNGLTAPNGPSQQRVIRQALANAGLASHQVDAVEAHGTGTTLGDPIEAQALL
ATYGQGRDSENPLWLGSLKSNIGHAQAAAGVGGVIKMVMAMRNGTLPKTLHIAEPTPRVD
WDAGAVTLLTDARPWPAGDEPRRAGVSSFGVSGTNAHVVIEEAPAETSDDAPAAPGADRD
HHTTDTLPWAVSAAGPKALRAQAARLLDHLTDHETPSTEVARALLTTRASLGHRAVIVGT
RPDDLLRGLRSLADGTPDARVTQGTAADGTHNPVFVFPGQGAQWSRMGLELADSFPVFDK
SLRECADALAPFVEWDLRAELAGGLGRVDVVQPASWAVMVSLARLWESFGVSPAAVVGHS
QGEIAAAVVAGALSLEDGARIVAERSRVIGERLAGRGGMASVALPAETVRARIEGFGERL
AVAAVNGPSSTVVSGEPAALDELLAALEGEEVRVRRIAVDYASHSSHVESIREELLDVLA
PIVPRSATVPFYSTVTGGLLDTEQLDAAYWVRNLRQTVEFEATTRALIADGLSAFVECSA
HPVLAVGVEESGASTVVGSLRREDGGAQRFVTSLAQAFTHGLPVDWSTLIGQGPVADLPT
YAFQRRSYWLAHRPATATTPRDPAEDHFWDAVEREDLPALATALDLDGDGLRDLLPALAG
WRHRSREQAETDSWRYRIAWHPPADPGPARPTGHWIIVSPDAAGPQVWHEAAQRALRDAG
ARVTLLTPDAATADRHMLAAALRTAAGDGQVSGILSLLALDGRTHPGQTTVTTGYAASLA
LIQAAADSELGAPLWCATRGAVGTRPDEPPLDAAQAQLWGLGRVVALEQPQLWGGLVDLP
EQADSTALRLLATALSGRDGEDQLALRATGLLARRMLRAPLGGTVPPRTWRPEGTVLVTG
GTGALGTHIARWLARNGAPHLLLLSRRGPDAPGAAELVAELAESGTRTTIAACDIADRDA
LEAELARIPGELPLTAVFHTAAVLDDGVVDALDADRVERVLRVKTRGADNLHELTRDRDL
TAFVLFSSFAATFGTPGLGNYAPGNVHLEALAEQRRAAGLPATAVAWGTWAGAGMAEGAV
GDRARRHGVFALDAEPATRALQQILDHDETCPVVIDMRWDRFAVVFTSERPSHLLDEIPE
ARRALAEAAPATVAEDEQEPSELVSRLAALPEDDRRRELTDLVRRNAALVLGHDDPASVD
ESRAFRHLGFDSLTAVELRNRLNSLTGLRLPASLVFDYPTPAGLAAHLYAELLGDAAEPV
AAVHQGGAEDDEPIVVVGMACRFPGGVGSPEELWQLVAGEGDAISPLPSGRGWDADALYD
PDPAATGKSYVREGGFLHDADRFDPEFFGISPREALAMDPQQRLLLETSWEVLERAGIDP
TSLKGTRTGVFAGMTHHNYGATHPALPVPEGLEGYRMTGSTTSVASGRIAYTFGLEGPAV
TVDTACSSSLVALHLAVQALRQGECAMALAGGVTVMSSPAAFTEFSRQRGLAPDGRCKAF
ADAADGFGLAEGIGMLLVERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRV
IRQALANARLTADDVDAVETHGTGTKLGDPIEAQALMATYGRDRNPAQPLLIGSVKSNIG
HTQAAAGVAGVIKMVMAMRHGVLPRTLHVDEPSSHIDWSQGAVSLLTAAEPWPETGHPRR
AGVSSFGISGTNVHVLFEQPAPADQAPTAPATDPAGTPHGVVPLTLTAGSEHSLRRLAHR
LHAHVENHPDDAPLAIGGALLRSRARLERRAVVVGADRSALLSGLASVAAGEPHAAVVTG
TPNGPGKAVFVFPGQGAQWSRMGLELADAFPVFDKTLRECADALAPFVGWDLRVELAGGL
GRVDVVQPASWAVMVSLARLWESFGVSPAAVVGHSQGEIAAAVVAGALSLEDGARIVAER
SRVIGERLAGRGGMASVALPAETVRARIEGFGERLAVAAVNGPSSTVVSGEPTALDELLA
ALEGEEVRVRRIAVDYASHSSHVESIREELLDVLAPIVPRSATVPFYSTVTGGLLDTEQL
DAAYWVRNLRQTVEFEATTKALIADGLSAFVECSAHPVLAVGVEESGASTVVGSLRREDG
GAQRFVTSLAQAFVEGLPVDLGSLVAASGDTVDLPTYPFERSRFWLESGELPASAGVPRD
EVEDRFWEAVEREDLESLADSLDLDGEELRPLLPALASWRRAGRQESVIDSWRYKTAWRP
LTDLADDDGSALSGTWLVVSPAAEREGATTPALVRALEDRGADVRLLEVSAGDADRTALA
TRISEAADGDVPFSGVVALWGLDDVPHPDFPALTGGSLGSLALLQALHDLGAEAPLWLLT
RDAVAVSDTDGLSGAAQAQLWGWGRVAALEHPKLWGGLMDLPAVVDERALRLAVGALAAP
PGEDQIAVRAAGVFGRRLVRSALVGRAPGRTWAPRGTVLVTGGSGGIGGHLARWLARGGA
EHLVLVSRRGKDAIGAPQLAAAIEELGARVTFAACDIADRDALAALVREVEADGPPVTAV
VHAAAHIELGMLADTTPGTLSEICRAKVLGAENLDAIFAERDLDAYVLFSSIAGFWGSGD
HGAYAAANAHLDTLAERRRARGLRATSVAWGIWDAANDWDERNTEMRALKNEKSSRHGLP
LLDADAAFTALRRIIDHDETVVAVADVDWDRFVALFTMARESALLAEVPEAARALAAPEE
EAAPAVGGDLARRLEGLSRPEQDHLLLDMVRAQAAAVLGHGPQAESVDAGRAFREMGFDS
LTAVELRNRLAATTGQKLPATLVFDHPSPVELAERLRVLLLPDDASAQPLALVRFGDFET
ALAAAPPDPATRQQLARRLQGLLWSWSEGDGPAAGAPAAHADDTAPVDVASASADELFDL
IDRGLGAS
>A0A2S5BBV0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Rhodotorula taiwanensis|TrEMBL
MKYVAAYLLAVTGGNASPKAEDIKTILGAADVSVDEERLSKLLAELEGKDINEIIAEGSK
KLASVPSGGAAPAAAAGAAAGGATDAPAEKEKEEEKEESDDDMGFGLFD
>A0A1Y2NHX9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces platensis|TrEMBL
MTGRLADPAELRTPEYWVRHVREAVRFHDGIQAAHAEGVTTFLELGPDGVLTAMGQDCLP
ETATLQPSLRKNRSEPEAVLQALGAVYARGVVVDWATFFPGARQVALPTYAFQRQRYWLD
RTGAGAGDVTSAGLAAADHPLLSAAVPLPGSDGFLFTGRLSLATHPWLADHAVMDTVLVP
GTALVELAIRAGDQVGCDLLEELTLQAPMIIPSTGGIQIQITVDGPDAHGRRELSMFSRG
EDGAEPWTRHALGVLTTAGALPLPDLGEAAWPPAGAEAVSVDGFYAELVDAGFGYGPVFQ
GVRAAWRRGAELFVEVALPDGAAEEAAEFGLHPALLDAVLQTFGLSDDLGTDGPGLPFAW
AGVRLHAVGAASLRARLTPTGDGGMRILAVDDAGAPVATIEALTTRPVPAAGQLARAGGG
QREALFAVEWAPVALPAGDVDGAWAVADEDVVPAAGLGVGVLDPSAESVPGHVAWSPDVK
PGASADVPGSVRGATAEVLQRVQTWLVDERFEGSTLVIVTRGAVSVASEPVEVAAAAVWG
LVRSAQSENPGRFVLVDVDGEAGSLQAVRAAVASGEPQLAIRNGVVSVPRLARIVPSGVD
GAPVWDPEGTVLITGGTGTLGALFARHLVSEHGVRRLVLTSRRGLEARGARELQSELTEL
GARVEVVACDAADREALGELLAGIPAEAPLTGVVHTAGVLDDGIIGSLNPERLNTVLRPK
VDAAWNLHELTEGLDLSAFVLFSSAAGVLGSAGQANYAAANSFLDVLAEHRRLSGLPGTS
LAWGPWAADTSGMTGQVEDTHLRRMAADGFLAISAPDGTAMFDAAVGADEAVIAPIRLDA
QALAASGAVPAILRGVVRAPVRRTAAEATSAGSLGDRLLGLPVEERDELLLDLVTTQVAA
VLGYENAGAVRIDQVFKDLGFDSLTAVELRNRLNSATGLRLPATLVFDYPTPAALLDHLR
DELVGDRDQPVVTGVATGTTVDEPIAIIGMACHLPGNVHSPEDLWRMLETGRDGISAFPG
DRGWNLDALYHPDPDHQGTSYTREGGFLDGAADFDPTFFGISPNEALAMDPQQRLLLETS
WEALESAGIDPTALRGTPTGVYAGLMYHDYVHQLQSVGEGVEGFMGTGNSGSVTSGRLAY
SFGFEGPAVTVDTACSSSLVALHFAVQALRSGECSLALAGGVTVMATPDTFIDFSRQRGL
SADGRCKPFAAAADGTGWGEGVGMLLVERLSDARRNGHRVLAVVRGSAVNQDGASNGLTA
PNGPSQQRVIRQALAGARLSPSEVDAVEAHGTGTRLGDPIEAQALLATYGQDRPEDRPLW
LGSIKSNIGHTQAAAGVAGVMKMILAMRQGLLPKSLHVDEPSPHVDWAAGAVELLAEARE
WPDTGRPRRAGVSSFGISGTNAHVVLEQAPEDVPAEPVEPVEGARPGVLPWVLSARSEQA
LAAQAGRLASFVEERPEVGLADVGLSLLSTRAVLEHRAVVVGAEREQLLSGLRGLAGGLA
GGFAGGLDGAGVVQGSVAATAASGAVLVFPGQGSQWLGMADELLASSPVFAGRMAECGAA
LSEFVSWDLMAVLSDEDALARVDVVQPVLWAVMVSLAAVWEDCGVVPSAVVGHSQGEIAA
ACVAGILSLRDGARVVALRSQAIGRVLAGRGGMVSVAGSREVVQERIAKWGERVSVAAIN
GPISTVVSGEPDALQELLAECAEQEVRARRIPVDYASHGAQVEELREELAAVLAEVAPAD
GRIPFYSAMHASVVSGEELDAAYWFENLRNPVRFEEAVQALLADGHGVFVECSAHPVLTP
GIEDTAQGASSPVVVTGTLRREEGGWSRFAQSLGRLWAHGVPVNWRTLLPTGRRVDLPTY
AFQHKRYWPATVVAAGDATGLGQADSQHPLLGAAVALPESDGYLFTARLSLATHPWLADH
AVLGAVVLPSSALVELAFRAGDQVGCDLLEELTVLVPPLLPEGAGLQLRVTVGESDADGR
RELAVFSRNEDAEADLPWTRHATGVLAAGAAPVGFGEAAWPPAGADTMTVDGLYDELAAA
GITHGPVFENVRAAWRRGADLFAEVALKEENEGEAGRFGLHPALLDAALHPATRQEVADG
TPLAAQWTGVTLFAEGATALRVKLSSVGDGYALVAADHDGEVVATAESIAWTAISEEDVT
AAGPGHRDSLFGVEWSELPLRSEPVAGSWAVLGEDVGLAAALGASGADVLSELVEVPECV
VLAVPRTDGALPVPAAVRAMVGRVLESVQSWLADERCTRSKLVIATRGAVSVMGEPLDAV
GAAVWGLLRSAQTENPDQFMLIDLDEQHSSVGAIAAAVASGEPQVAIRDGVVSVPRLVRT
APSDSAPVWGSEGTVLITGGTGTLGALFARHLVSEHGVRSLVLTSRRGLEADGARELRSE
LTELGARVEVVACDAADRDALAAVLASIPAETPLTGVVHTAGVLDDGIIGSLTPERLDTV
LRPKVDAAWNLHELTQGLDLSAFVLFSSAAGVLGSAGQGSYAAANTFLDALAEHRRLRGL
PGTSLAWGLWADASGMTGQLSETDLRRMARGGMIPLGQAEGAALFDAAMAADQPVALSAH
LDLNAIAGTGEVPSLLRSLVRVRRRAVTTGSATADTLAERLRPMTEAERERTLVELVRRQ
ASAVLGYDGGDAVGTTRAFKELGFDSLTAVELRNRLNAATGLTLPATLIFDYPNPEALAR
YVREELLGTVAAPVAAVPVARPVDDDPIVIVGMACRYPGGVASPDDLWQLVTSGGDAISG
FPVNRGWDLDNLFGGDSAETGKSITQQGGFLYDAGEFDAGFFGISPREALAADPQQRILL
EAAWETFENAGIDPLALNGSQTGVFTGINYHDYAPADGNVPEDIEGYLTTGGAGSVLSGR
ISYSLGLEGPAVTVDTACSSSLVALHLAIQALRSGECSMALAGGVCVMATPGNFVEFSRQ
RGLAADGRCKPFAGAADGTGWAEGAGMVLVERLSDARRNGHPILAVVRGSAVNQDGASNG
LTAPNGPSQQRVIRQALANAGLEPSDVDAVEAHGTGTTLGDPIEAQALLATYGQNRPADR
PLWLGAVKSNIGHTQAAAGAAGVIKMVFALQQGLLPKTLHVDEPTPHVDWTAGAVELLTE
TRKWPETGRPRRTGISAFGISGTNAHVILEQAPAEELATTAPTTTAPTTTGPATSGPVTS
ETAEAAPAESGPAGALSWTLSARTQEALYAQAGRLVSFTAEHPELAPADIGFSLATTRAA
LEHRAVVTGADRDALLAAAGRLAAGEHPTAVAGDGRVGVLFTGQGAQRLGMGRELYDTYP
VFARAWDEVCGELDGLLPRPLAEVIWGEEDLLDQTQYAQAALFALEVALYRLVESHGVTP
AVLLGHSIGEVTAAYLAGVWSLADAAKLVAARGRLMQELPAGGVMASVRASEDEVAPLLE
GCEQVGIAAVNGPESVVISGAEAEVEQIAAALEAEGRKVKRLRVSHAFHSPLMDPMLAKF
RAVLDQLTYNQAQLSLVSNVTGRLADPAELRDPEYWVRHVREAVRFHDGIQAAHAEGITT
FLELGPDGVLSAMGQDCLPQTAAATASATLQPSLRKDRPEPGALRDALGGLWAHGVAVDW
TPLFPGARRVALPTYAFQRQNYWLQANTGSGDVSSIGLGAADHPLLGAAVTLPDAVVLTG
RLSLATHPWLADHTIMDTVLLPGTALVELAIQAGDQVGCDLLDELTLHAPLILPPHGGMQ
LRVTVGEESAGDGRRALAVLSRNENEPDQEWTRNATGTLTVATDTPVRFSESVWPPADAE
RIPVDGFYEELVSVGFAYGPVFQGLRAAWRRGAEVFAEVALPEEPGADAAKFALHPALLD
AALQTVGLLGDAVSGLPFAWTGVRLHAVGATALRVRLSPAGDGGVQVLAADETGAPVATI
DSLVTRPVPAEQLGSTTRRGALYELAWTALEEEAAEPVPGSWTVVGPDAEKVAEPLRRAG
VDVSTCPEPAQAAGRDAAPDFMVLPVSVSVPVSVSESGGRTEARPSSGAGTEATPAAARA
AVHSVLGTVQEWLADERLAGTRLVVLTRGAVAPDGAPADLVTTPVWGLLRSAQSEHPDRI
VLADLDDEDASMAKLPALIAAGEPQAAIRRGVASVPRLAALEPSGQDSATVWNTGGTVLI
TGGTGVLGAEVARHLVTGHGVRNLVLTSRSGPTAEGAEELRAQLTEVGARVEILACDAAD
RDALAAVLAGIPADAPLTGVVHTAGVTDDGVITSLTPDRVDRVLRPKVDAAWNLHELTQD
LDLSAFVLFSSVAGILGAPGQGNYAAANTFLDALAAHRRAAGLPAVSLPWGLWARSSGMT
GKLGEADLRRIGSGGLVPLSSEAGVALLDAATVAGPAVVLPMDLDPRKPAASGDIPAVLR
GVVRAPARRAAAAGPAVAEVSLGDRLGAVPAAERSGMVLDLVRTHVAAVLGHAETGKMKA
DQQFTELGFDSLTAVELRNRLHTATGLRLPATLIFDYPTSAALADHILGEVVANEPDPVA
TVLATIEKLEAGLSMLRTESGDRRDITKRLERALSQYRDGDTAEFGGDTDSDIRDASTDE
LLDVFDREFGNS
>A0A6N3J6U9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Shewanella sp. (strain W3-18-1)|TrEMBL
MSHTPSVPNSATESKKDKRLNKRLKDMPVAIVGMASIFANSRYLNKFWDLISEKIDAITD
IPDTHWRAEDYYDADKSKADKSYCKRGGFLPEVDFNPMEFGLPPNILELTDTSQLLSLIV
AKEVLADANLPIDYDRDRIGITLGVGGGQKISQSLNSRLQYPVLKKVFKSSGLSDEDSEM
LIKKFQDQYIHWEENSFPGSLGNVIAGRIANRFDFGGMNCVVDAACAGSLAAMRMALTEL
TEGRSDMMITGGVCTDNSPSMYMSFSKTPAFTTNETIQPFDIDSKGMMIGEGIGMVALKR
LEDAERDGDRIYAVIKGVGASSDGKFKSIYAPRPEGQAKALERAYDDAGFAPHSIGLVEA
HGTGTAAGDVAEFNGLKSVFAQGNDTNQHIALGSVKSQVGHTKSTAGTAGVIKAALALHH
KVLPATINVSKPNPKLNIESSPFYLNTETRPWFQRADATPRRAGVSSFGFGGTNFHLVLE
EYKPEHSRDEQYRQRSVPQTLLFAAANKAALLSELKAALSQSVNTSANANKSSAASLNAI
AQQYPLRPLASTDARLGFVAKDIAQLQAQLNQAISHLESSAHLESGHLETSASEAWQLPS
GISYRSHALVAKNESKKVAALFAGQGSQYLNMGRELACHFPEMRQQVTASDKVFAHHGQT
PLSNILYPIPAFDADAVKAQEAALTNTLFAQSAIGAISMAQYSLLTQAGFAPDMVAGHSF
GELSALCAAGVISNEDYVELAFARGHAMAQVPSDTASKAVDLGTMFAIILKQKNDIDALN
RCLAQFDGVKIANYNAPTQLVIAGGTEQTQLAAKAISELGFKAIALPVSGAFHTPLVGHA
QKPFAKAIDKAKFSAPSIALYANGTGQLHPTDGKAIKAEFKQHMLQSVRFSEQLQAMYDA
GARVFVEFGPKNILQKLVENTLGEHLNELCLVSMNPNPKGDSDSQLRLAAVQLAVAGVAL
TEVDPYQAVTSQEIAEREAPSAMNIKLTATNHISAATKAKMAKSLATGSVTSQVQYVDRI
VETVVEKVVEKEVIVEKVVEKIIEVETNQVATVEMKQKSPSVAQGLSNHQQQATAQLSPS
TASVSGDALTAFFSAQSQAAQLHQQFLAIPQQYGDTFTTLMTEQAKMASLGIAIPESLQR
SMEMFHQHQAQTLQSHTEFMQLQSSSSQAALAMLNNAPINFTPAVASQPRATAPAPASVD
PAPVAATTMPHNAAPVTQAVATEAVSTPVAPVVQTAPVAYSPAVTVQVAPAAPALVMPAV
VMPEVTPAAPATSGLSAGLVQASEIESTMMAVVADKTGYPTEMLELGMDMEADLGIDSIK
RVEILGTVQDELSGLPELSPEDLAECRTLGEIVDYMQSKLTQNDKLPAVGSIIVAPITTA
NVATQVATAAPAVNGLSAALVQQTMMAVVADKTGYPTEMLELSMDMEADLGIDSIKRVEI
LGTVQDELPGLPELSPEDLAECRTLGEIVDYMNSKLPAVGSVSAPIATSVTVATNNGLSA
ALVQQTMMAVVADKTGYPTEMLELSMDMEADLGIDSIKRVEILGTVQDELPGLPELSPED
LAECRTLGEIVDYMQSKLTQNDKLPAAGSVVVSTTAQAAPAANGLSTALVHASEIESTMM
AVVADKTGYPTEMLELSMDMEADLGIDSIKRVEILGTVQDELPGLPELNPEDLAECRTLG
EIVALFSKEIGQSKLGQNAVSQNAAPVSAVVQPEPTIDLPPHDLPPHSEVVLKKLPAAAE
LTQLSPQQSSKQSAQQGLPRVFAKDACIIISDDGHNAGVLAEKLHAQGLTVAVVRSPESL
VASASPLNSHIASFTLAAIDDASISAVINEIKSLGTVAGFIHLQPQHKTSADAKGLVLSS
AAKASVEQAFLFAKHLQPFLTTAATANTGSSFISVSRIDGGFGYLNHSQIARSELNQAAL
AGLTKTLSHEWPNVHCRALDIAPALDAKQLANAVIAELFATDNVLEVGVSQGAAQALERV
TLVAGKANTRHNAANLTSADKILVTGGAKGVTFECALSLAKRSKAHFILAGRSSQQTIPA
WAQGKNNSELKAAAIAHIQSLGEKPTPKQVDALVWSVQSSLEIAAALEAFTAVGASAEYL
SLDVNNPDAIASTIVPITELSPITGIIHGAGVLADKHIQDKTLDELARVYGTKVTGISNL
LAALDLDKLKLIALFSSAAGFYGNTGQSDYAMSNDILNKAALQLAQQLPNAKVMSFDWGP
WDGGMVNPALKKMFMDRGVYVIPLKAGAELFASQLLSNTGVQLLVGTDMQGSAPHDDTSN
KLQETEGSNLKKPEADLTTDASGPHALASTLAAIAFTRPLTLQRTLDPKAMIFIEDHCIN
GHPVLPTVCAIQWMREAAFDVLKQPVKVQSYKLLKGIIFDTAVLQNGVLESEAPITLELE
LAPIALTDNAATNTDERLSEQFSALISFEGRPQYQAILVVDDAVDDAASDYLATNSKATA
FDAQSLAGLSVITTASSLYSDGTLFHGPRLQGIESVLKFDDASLIAKVSLPHVALADCGS
FVPNLAPKGSQAFAEDLLLQAMLVWARLKYGAASLPSSIGEFISHAPFAFGDKGYLVLEV
VKHSGRALEANITLYHQDGRLSCEMNNAKVTISKNLNGAFLANKVAANQTAANKAIESVE
AKVE
>B1ZYL3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Opitutus terrae (strain DSM 11246 / JCM 15787 / PB90-1)|TrEMBL
MSASDNEPLARPNDIAVIGLALRVPGARNVEEFWANLRAGREAVTFFTDEELRRAGVEAA
KLANPRYVKANAVLADADRFDAEFFGYTPREAELLDVQQRVFLECAWTALEHAGYDPLAV
PGACAVFAGAGLNTYLLRQLMQNPAAVESAGGFQVLIANDKDFLASRVSYKLNLRGPSVA
VQSACSTSLVAIHLAVQSVLAGDCDVALAGGVSIRVPQTEGYLWQEGMILSPDGHCRPFS
ARGAGIIGGNGAGVVVLKRLEDALADGDTVHAVIRGSAVNNDGSAKLGYTAPSQEGQEAV
IAEALAVAGVVADDIGYVEAHGTGTPLGDPIEVAALTRVFRRTTPRTQFCALGSVKSNLG
HLDTAAGVVGFIKAVLAVKHGEIPPSLHGESPNPQIDFASSPFRVATELTAWPMAAEAPR
RAGVSSFGIGGTNAHVILEQPPAMRVGPASEEDQLLIVSARTEAALRQSGAALAAAVSGG
HLPLADVASTLALGRRAFAHRAYVVARDPADAAQQLRAVEPAVAGERMRQVAFLFPGQGT
QYPGMGAGLYAAEPVFRTEVDRCLELLRPHVDFDLRALLLDRTGDARLLARTDVAQLALF
VVSYALARLWEAWGVRPEAMLGHSIGEWTAACLAEVFTLEEALRLVAARGRLMAAQPAGA
MLAVALGEADTRALLDDRFDVAAVNAAGQTVVSGTIAAMTALADTLAARGIGSTRLQTSH
AYHSAMMEPAAQALMSAFHEVPRRAPTRRWISSTTGTWITPEQAADPGYWARHLRGTVRF
ADGLATLLTDPEIALLEVGAGRTLCGLAERHPARGTGRVMAHSLHGAREATTDETTMRHA
LGRLWVAGVPIAWAEVYREQKRRRVPLPTYPFAGERYWIEAQPSGARNVDVGGKRQDPAD
WFYVPGWRRGLALAALPPITGGEWALIPDASGLAERLAARLRGLGAAVRIGADPTKLLGA
RWIVSLRDVSAADASEPKLDELCALGRVLSSQALAETRLTVVATGLHAFPGENSAEPAKS
LLLGAARVLPNEIAGMSVRVIDVARAELSAESLLDALIAEARGGEDEFVALRGRERWMQT
LEPVRLEVGEAKPCRPGAVVVITGGFGGLGLALAESLFERARARLVLVGRSTAAAAAQQR
IDALIARGAEVITAVADVTDESALQRVHAQIRSRFGGCQGVIHAAGVAGGGALARRDPVA
AAAVRAAKVAGTLVVDRVFGAEALDFFVLMSSLTAQLGEFGQADYAAANAFLDAYATARR
REGVPMVAIGWDAWRDVGMAARFEPQGALAAWQERQKELRLTNAEGAEVLVRAVAAGVPH
VIVSTVDLAWRRRQTRAPKGTTSGATKDAVPARAAHPRPALPVTFAPPQTATQRKIAAVW
EELLGVAPVGVNDDFFALGGHSLLASQAVARLRDAGVNGLTLATFFEAPTIVRLAATVAA
DSADEPALVPAARAGRLPLSFAQQALWLLDRMEGRSAHYNEFGAQRIRGPLEVARLRRAL
GMIVDRHEVLRTRFVEQDGEAAQVVDPPAALELPVEELPESRLAARAAEIAGEAFDLVRG
PLLRARLVKLGPDDHVLMIAVHHIVFDGWSSAVFFREAMAAYAALARGADPALPALAVQY
ADYAVWQRRWLTGARREALAAFWKEQLAGPLPVLALPTDHPRPATAGHRGRRLPLEFGAD
LTSRLRARAQEQGASLFMLVLSGYGAVLGRTAAQEEVIVGCPMAGRERRELEPLIGFFIN
PLPIRISLAGAPRLTDVVERVRGRVVAGFAHAALPFEQMVTAVQPPRDPSRSAVFQTVLT
FQNAAGVSGSAAGTSLQLEPWERDEVPVRTDLDFYCWETPDGLRGYFVYNVDLFTAATVQ
RLATRLRKVLETLAADPATRLAAVAFEAAALPALRPVRSTPTPNAPKLSVP
>K9PJ45|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Calothrix sp. PCC 7507|TrEMBL
MNNFSTEIEVKSGLEIAIVGMSGRFPGARNVDEFWQNLKHGVESIAVFTDEELLSRGIDA
AILKNPDYVKAGAVLEDAELFDAAFFGFSQQQATITDPQLRLVLECAWQALEDAGYDSQQ
YQGAIAVYAGASLSSYLVKLLSNPHLRGAIDESQVLMSNDKDFLTTWVSYKLNLEGPSCT
VQAACSTSLVAVHLACQDLLSGNCDLALAGGVSLDLPQNRGYLYQASGILSSDGHCRAFD
ANAQGTVYGSGVGIVVLKRLEDAIAEGDNIYAVIKGSAINNDGSAKASYSAPRVDSQAKV
IKNAQFMAEIPPESITYIEAHGTGTLLGDMMEISAMHQAFRSSTEKTGFCAIGSVKTNIG
HLKIAGGIAALIKTVLALKHKLIPPSLHFQQANPQIDFAHTPFYVNTQLSEWQINSTPRR
AGVSSFGIGGTNAHVILEAAPDEQKHDIVFERSHPCHLLLLSAKTSSALQTATINLVNHL
KQHPDLHLADVAYTLQVGRRSFEHRRMLVCQDIETAISALESPDSVTFYQEACSHSLVLV
FPGEDSQYLEIGKELYSTAPLFREHIDYCCEQLQPHLNLDLRHILYASAEQVEIAPQQLQ
QTALFVVLSALAKLWLAWGIQIEAMIGCDIGEYIAAYLAGVFTLEDALVLVALRERTPQL
SSEFTTYIQQVKLQPPRIPLISAITGTWIATTEVTNPTYWVQQMHCKSISLSPEIQNLMQ
EPKRIFLEIGTGKILNSWLLQQEQVKSLLLTSIPDAQTDKSETDFLLNTLGKLWLKGVQI
DWSSYYAHEKRHRLSLPTYPFERQYYSIDSLVNNIPEFSKKSGI
>A0A1N6AD30|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus subsp. bolletii|TrEMBL
MLRREASALLAYVAEHPRIAPNRIAGMIFRTRVARRYRALVTVENHDQLVAALRTVVAGT
EHPLVVRNSEPATARRHGFVFPGQGGQRPGMGRLFYDAFPSFRAEVERCADLFAKQFGRS
PLSYLLDDQLPPNDSATVVQPALFTQMAGLAALWRTVGVIPRAVVGHSQGEIAGAYVSGV
MSLDDAVTVVGTRAGIADKFPADDYAMAVIATDRDTCEELLARNSGWAELSVINSPSMVG
ISGQRETVHQIVEHLTGDGVFARVIPVRYPAHTSMIASIGAQIRHALTENLHAGEFTVSE
IDCIGATLGTAISPEMPVDEYWFWNLRNAVRFDRAVATAAAAHIDTFVELAEHPTLQLAL
RENLAALGSERTACVVSTSHRNATDLAEFTANLAKIAVHDLDYNWDALRAEAPDRVSLPL
RDFPNVQNNDIPLWLSYRAGTSGVAVPKQPAVTPEAERRVDTGNDSRAYPRLLREAWTKM
TRRSMMPPRSYAFIDGTGDAGALVEALRDNAPNFGSSARIVTGTNESGAGDADTVVIVLP
SPALLDDREAAEAVARFFGNRTWWPGLSSTVTGCWLVTVGGEQAVADDRPAHPVHAAIAA
GFRCMGTEHPGIAFRHLDLTPDIAGPDKADNILAALQSAGESELALRADGMYAKRVLDID
QDGDESSRAVAPDHVVITGGTGKLGQEFCEHYARMGTRQITLISRSGETDAVTGRLDAIR
RSTGAKVRALPCDVTDTAAVTALADQLRDTPADLIIHAAVDYSDTPLAEVTVDKFQDALR
AKVIGISNVLDTVPRTDSCRVMLCSSLAATIGGKGQLMYAAGNRMLDVLASTRRASGLDC
TSIQWGQWTVHLDLGDTGIAKLAAAGVHPMRPADALAVGMGRHHGNTLVGAFDLTQARAM
LGVFGYGPLLSELEDNGGPVAPAETIRPAPVVPENRSGHLVQLLAEVIGADHADSIDTAM
PMVAMGLDSLQALEFRRRVQAELDFELPVQDLLGGASVDHVIDALTAQSR
>A0A4P6Q2F3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomonospora litoralis|TrEMBL
MNHAPTDADRSQSSEGTERVVAALRSAMQENERLKQDNRRLAAAESAAAEPVAIVGAGCR
LPGGVGSPEELWELVAAGGDATSEFPADRGWDVEGLYDPELRRGGTSYVRRGGFLAGAAE
FDAGFFGISPREALAMDPQQRVVLETAWEAVERAGIDPVSLRGSRTGTYIGAIAQDYGPR
AADAGEETAGYSLTGSMTSLVSGRVAYVLGLCGPAVSVDTACSSSLVALHQAVQALRRGE
CDLALAGGVSVMASPGVYVEFSHQGGLSRDGRCRSFGAGAEGTGFGEGAGVVVLERLSVA
LARGRCVWGVVRGSAVNQDGASNGLSAPSGAAQERVLRAALADAGVGPEAVGVVEGHGTG
TRLGDPIEAQAVGAVYGAAGSGVVLGSVKANISHVQAAAGVAGLIALVGALGRGEVAPSP
GVAGGVSELVDWRGLGVVAAPEGRSWPVCGGGSRVGGVSSFGISGTNAHAVVEQAPEAAV
RPRAFERGRTGARASDSPASSARLPWLVSGRSPAALRDQARRLHEHLGADPGARVDDVGF
SLATTRSRFEHRAAVLGGDRVRNLDALAALARGETPPEAVVGRADAPGKTVFVFPGQGAQ
WPGMAAELLDTSAVFAEHFAACEQALEPHVDFSPAAVLRGEPGAPSFERVDVVQPLLWAV
MVSLARLWISCGVRPDAVVGHSQGEVAAACVCGALSLEDGARVAALRSRAVRELGGDGAM
ASVPLPAERVRELIADRGRALAVAAVNGPESTVVSGDRAAVEDLLEHCAASGVRSRAIAV
DYASHSAHMEALRPTLRSGLDGLSSRRPRVAFHSTVTGRPVAEGELGAEYWYANLRNTVE
FASAITALAEDDHGIFLEVGPHPVLAMDIEQTADRVAEEADPNGRHTRRPAVVGTLRRDD
GGLRRFLASAAEAHAHGAQVDWPAACADGGHTRVDLPTYAFQRSRFWSDPAPRTTGPESP
ADAGDARFWQAVADGDTAALAADTGADPAALDAVLPALARLRRRNRARAELDALCYREHW
IPVPEAAAAPVAPPAGGTWLVLLPPPTEAGSAAAHRWHDALRERGLPTEVAEVPTGRCER
GGLAALLGGITDPGRTAGILSLLTVGHDASRAGPPSADAGPAAAAALLQAVSGGAPAAPV
WWATTGAVAADEGDTVRAPAAALTWGLGRVAAQEHPQNWGGLIDLPEHPDRRTAARLHAA
LCAPRGEDQLAVREGGTYARRVVRTTARTPGPEDADPLPLAGTVLITGGTGALGARTARF
LAERGGGDLHLLLASRRGEDAPGAPELAAELAASGSRVTFAACDVADRTALRSLLARVPP
RDPLTAVVHAAAALDDAPVAELDAARMDAALAAKAGAAWHLHELTAEDDLAAFVLYSSVG
GMFGVAGQGNYAPANAYLDALARHRRSRGLPATAIAWGAWRGGMAEGEGAAAVLQRHGMP
AMDAATALPVLEPVLAGRTRDAFAFAGIDWRRFAVAFTAARPSALLDEIPEARQAVAESA
QTSAPQRAPEGAGGEGGRPADTAADLRRSLAAVVAPERDRRTRALVRDCAAAVLGHASAD
AVDEARPFNDLGLDSVMAVDLRNRLAAATGLRLSPSAAFDHPTVPELAAHLRAGLGVDTG
PEPQAGPGEPGAAEIAALEKVIGELTPERLNSSGLPERLRALLRACGPSHGAPSETDEEP
DRLADATRDELFAFIDRELGT
>A0A4P6Q662|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomonospora litoralis|TrEMBL
MTEGNEQLVAALRASVRENERLKQADNEPVAIVSMSCRCPGGVSSPEELWDLVAAERDAV
GPLPGDRGWDLDRLYHPDPDHQGTCYVTEGGFLDGAGRFDPGFFGIAPREAEAMDPQQRL
LLETSWELFERAGVLPQTLRGSSTGVFLGAAWQGYGEGWRDLPDGLQGHLVTGMSTSVIS
GRLAYTLGLEGPAITLDTGCSSSFVALHLAMQSLRRRECALAVVGGAAVMSAPISLVGFS
RHRALARDGRCKAFSADADGMGLGEGAGTLLLERLSDARRNGHPVLAVVAGSAINQDGAS
NGMAAPNGVAQQRVIRQALANARLEPADVDTVEAHGTGTSLGDPIEAEALLATYGRDRSP
ERPLWIGSLKSNIGHAQAAAGVLSIIKTVQAARHGVYPRTLHADEPSPNVDWSDGVVAPL
REARPWPRAGAPRTAGISSFGVSGTNAHVILREAPPEEATEEAADRPAARPAALPLVLSA
RTGDALRRQAAELRTRLADDPDPLDVAYTLATARTAFEHRAAVVGTGTADLRAGLAAVAG
GAADGEVVRGTVRRGLDRRVVFMFPGQGSQWAGMAGRLVAESAEFAERMAECDRALAPFT
GWSLLELLEDEDTAWMERVDRVQPVLFAVMVSLAAMWRAAGVEPDAVIGHSQGEIAAACV
AGALSLDDAARVVALRSRALTRIAGGGGMMSVALPPERVRSLLERRSALSLAAANGAAST
VVSGPAEELADLARELEEDGTRTRRVPVDYASHSADVELLHDELLDALAPVAHHDGEIPF
YSTVTADRLRLSAVGPEYWYRNLRRPVELEHVTRLLADHRHDVFLEVSPHPVLTPAISET
LADQGRLDSAVVVGTLRRDEGGLDRFLRSACELHVSGVAVGWDRLLPGGRTVDLPTYPFE
RGRYWLDAPAPGAAAPSETDTWRYQVAWRPADSGTEAPALRGDWLVAVPAGRGGAPLVED
VLEALRTHGARPVPVELDAAHDDRASIAERLRACGAPAGALSLLALADEPVAASGRSTGT
TLNTALVQALGDTGGQVPLWTATSGAVAVRPGDTLTAPDQAAAWGMGRIAAVEHPHFWAG
LVDLPERLAAPAASRLAAVLAGAAGEPQVAVRASGTYARRLVPASPAAQRWTPAGTVLVT
GGTGALGGHVARWLARNGAEHIVLTGRRGPRAPGAEELRAELAELGAEATVAACDAADPD
ALAELLETLPSLDAVVHAAGVLDDGLLDGLTGERCDAVFAPKVAAARNLHELTRDRDLSA
FVLFSSFAGTLGGPGQGAYAAANAYLDALARHRRDHGLPATAIAWGAWDGGGLVDEETAA
RLRSTGMPAMPPDRAVEAMGRAVGSGDTAVAVADVDWALLTASSPLTGDSPVVSEIPAVK
ERRAPARQADGDDGGRWTRLHGEERERALTDLVVGEVAAALGHDAATLATDRAFRELGFD
SLTAVDLRNRLAAATGLTLPVTLVFDYPTADELIRHLSEALPGGSGEAVEEAAAAPPAAT
AAAAEEPIAIVAMSCRLPGGVSTPEDLWRLLDAGGDAVGPFPRDRGWDVDGLYDADPDTP
GTYYVQGGGFLRGAADFDAAFFGISPREALTTDPQQRLLLETAWEAFERAGIDPRTLKGS
PTGVYVGASYNDYGARVSQPSEHEGYLALGSASSVASGRISYMFGFEGPALTVDTACSSS
LVALHLAVQALRRGECTLALAGGVVVMSSMDTFVEWSRQRAMAPDGRCKAFSADADGAGW
AEGVGLVLLEPLSQARRRGHRVLGLVRGSAVNQDGASNGLTAPNGPSQQRVVRAALEDAG
LGPDDIDAVEAHGTGTSLGDPIEAQALAQVYGENGRERPLRLGSLKSNIGHTQAASGIAG
VIKMTLALQHERLPKTLHAERPSPHIDWESGPLAVLTESAPWQRNGRSRRSGVSSFGVSG
TNAHVVLEEAPVFEGGPAGSAEPGGEVPVVPWVVSGRGVSGLRGQAERLARFGREAPGVD
VGAVAAGLAGRSGFEERAVVLGSDAEEVSAGLDAVAAGAAPVRGAVGRARAGRVGVVFSG
QGAQRLGMGRELHGRFSVFAEVFDAAVAELEGHLGSGVRDVVWGEDARVLERTVFAQAGL
FAVEVALFRLLESWGVEPGCVMGHSVGELAAAHVAGVWSLADAARVVAARGRLMEELPEG
GAMLSVDAGEERVAGVVHAVAEAGGRVDVAAVNGPHSAVVSGAESAVDEVERILGDDGHR
VRRLRVSRGFHSALMEPMLDDFRRVLEEVEFSPPRLGVVSNVSGGVAESDELCSPEYWVR
HVRQTVRFADGVGAMAEAGVSRFVEVGPDGSLVSQVQACLDSDDAVLVAALRRGRGEVEA
VLGAVADLWVDGTPVDWREVVGALDAHSAERAARIELPTYAFQRQRFWLEAGGSDAEARN
RHGLVDRAVELADGRGVVWTGRVSVASHPWLADHAVGGRVWVPGTALLELGLHAALGTGC
GGVEELTLQQPLVLPPRGEVELQVVVEQGERPGIAVYSRSAADEQAAWRCHAEGTLATDA
GSPPTSAGVPETAEELSAEGLYDRLAEGGFGYGPAFQGLQRVWTDASTGDGAVFAEAALP
DPVREQAQEFVLHPALLDAALHALAFAELEGLDGGLLPFSWSGVRVYAAGAATVRVRIVP
LGGGGVGLLATDAAGSAVAEVERLWLRPAGTAGSAAAASALPLYRPDWQAVDVGWAGSAR
PAVLEAGAGAESLRDLPDPVPELVAIPHKPWTGELAAAPEAARQATGWALALVQAWLADE
RFADARLAFVATGPPADDDIVTAAVWGLVRSAQNEYPDRFVLAVADDAGSAAESLLAARG
EAELRVEDDTVRARRLVPAPPDDSAVLPDTDGTVLITGATGGLGALIARHLAEHHGVRSL
VLTGRRGAEAPGMPELRAELAALGARVTVAACDTTDPGAVAEVVGGIPADLPLKAVVHAA
GVLDDGVVSGLTPERIATVLRPKIDGAVTVWEQVRHLDPAAFVLFSSVSGTLGGAGQGAY
AAANAALDALATRLRGEGAPVTSMAWGLWAQSSGMTEKLGEADLRRVARSGVEPMESAEA
LALFDAALRTAEPVVAPVRLDTAALRRAAQDGLLPPVLSALAPGTGERRGAVPALVADVP
APAAPVAGPAESLADRLAALPETESRNTVRELVRGTAAAVLGYAGAEAIDSEQGLLDAGF
DSLTAVELRNRLNKATGLRLPVTLLFDYPTAAAIGEYLCGELLPDPEARARAELDELEQR
IRGFAENGAGRDRLARLRAVLDSVQENGGGAEEGATATRIESASDDEMFAFIDQELGISD
E
>A0A1S8SXH6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Clostridium puniceum|TrEMBL
MEEKNNEKISISCGKAISDEYCNKKNIANLLIESAQKSKDKGITFIQNDNTEIFFSYEEI
LEKALYCLGELEKSELKQDNFVMISFQDNIDFVVAFWACVLGGFVPVPISPPSAFKGKNA
SLEKLINVWNTLKKPVMVSDISMITNMKNNDFYPECQQIKMLDISILRQSKTKGSINLSL
TEKPAFIQFSSGSTNSPKGVILTHKNLLTNLAGIIESAELKAEDRVLSWMPYYHDMGLIG
FHLTMVALGLFQINMSPMKFVKRPTLWFDLISKYKITLTSSPNFGYRLLLKKITDKHLES
WDLSSLRLIFNGAEPISVPLVREFMEKLSVCNLSETSMYMVYGMAEACLAVAFPKAGTKP
ESHFISRNSLINKSLAEEVSENDIDSLQVANEGYAISGMQVRIVNDEGKIVPEKQLGEIQ
IKGENVTAGYINNPEATNKSFQDGWLKTGDTGFMIDGKLCVTGRIKDIIFVNGQNFFSYD
IEFKIEETDGVEPGKVVIGGWHDEKEGREKTAIFSALRIKKDEMKEFYGNMLKKINEAFG
ISVDYVVLVKAIPKTTSGKVRRFMMVQSLLNNEYEDTTFTSDELLFNEEENRIEKKSERI
EQVKHLVLDKNANKIREIWATVLDKPAESIGYNQSFLSLGGSSIKAVQVLGLLEDEFNLE
LGHDILINCKTINEMDEYLIKLSKENISEANITRRISKGINEEDDIAVIEMSCRFPEAKN
PEEFWNNIVSGKCSISEVPEDRWDINQYYSKNSDPTKTNCRTGAFINDAFDFDAKLFNIS
DEEAAVMDPQQRIILELVFEILERAGYSRKTVGGKRLALYIGAGTNTYQEYHLNTLNMSN
LRNFDSFNSLTKDVQESILKEWKNKLGVTEFHSNLLVDNIINMIAARTSQEFDLKGPSIT
VDTACSSSLVTIHLACESLRKGECELAIAGGINLLLTPTPYIYLSNAGALSTSGVSRVFD
AKADGLVPGEGAGIVLLKPLKKALEDGDKVLAVIKASSINNDGHSIGVMAPNPNGQREVI
ESLYLNNGIDPNEIQYVEAHGTGTKIGDPSEIRALTSAFKRWNPKNNSIAIGSIKANIGH
LLNGAGIASFIKVVLAMNNKIIPPNINLNELNPSIKFDKTPFYTMLEAKNWDANEGSLRR
AAVNSFGFGGTNCHMVIEEAPKLVEEETARQYERKRHILAISANAEKSLKLKINNLTGYI
KANKENRLSDICYTENTSKTFFKYRYSVVCESVEDLLSKLEDIKLKNTSYEIQHKIALMF
TGQGSQYVGMGRMLYEKLPIFQKYIDECSEAFYPYLNEKITNLIYSDQADEKILEQTNIT
QPVVFAMDYAFGKLFLDLGVKPAYMLGHSVGEWSAACLSGVISLQEAAKIVTARGTLMNE
LQSEGSMCAVFTSGDKLELLLKNFDGNVWIAAYNGTHQVISGERKDIDKFCIVLLKEGIG
MKKLKVSQAFHSPLMNPMLDAFREVLSKVTFNTPKIPIVSNVTGQIMKEPFDTEYWVEHI
LSSVKFEQSIKYLVDKSVDIFIECGPDRVLSRMASGIQTNNNTTILLSSDRREDSLDIVL
KTISSLFDLGIDINFEKLESGIYYKRIKLPSYPFDRKEYKPDFGIGNIKVPDNWFYNWKW
VPDKLREHLNSLPSGNIVIFDDGSGIQEELVSMFDEEKNKVYVVKVGEEYSYDGNREFLI
NPILENDYVELFKNIQGDIAAVIHLWNLKEEISKLEAVFNDKVIHGDIYSILYIGKALLK
FNIENVKVLLATNSAVPIDEEHKISAPHQSIAVTLAIALDQENSFVNSHCVDIDKNEYKS
DREIAQTLFNEIISEANSEGITVIRNGIKYSRDLVNIVELNKSSKIKFNDGETYLITGGL
SAVGGEIAKEVAKKAKINLILTGRKELPLREKWDKEMLNNTKSAKKINLILKLEELGVNV
SYESVDVTKMNDMKALIIRINNKYGSIHGVIHAAGTLDSSTFKLLNKEIKVVNSVIEPKL
QGGVITDLVTRKEPLKFFVMISSVSCSKKIWSAGLGDYSAANSFLSAYSFYREADGAPGK
TIALNYSLWASIGMGSDLGESTDLALKAQGLNPLAPKKAVEAFMRVLSDGNQRVTHIIDK
VEILNEKKTFQTKVTKLNLKKIYNIKEIVYNVISKQLHIKQDELDIGQNFLELGLDSLGA
VKVMEMLGTNLGMELYPTLIFEYQTPESLAEYIEKAYVQDFDEIALDKTDTLEEDNFKVE
KIKDIAIISASLRIPGANSLDEYWKILEEGKCVIKEIPSERWASKGWFSTDSNSTHTIYS
KYGGFIDNPYGFDPLFFGMSPSEANVTDPQQRIFLEIAWEALQQAGYGGRYNTNNIGVFV
GCEQNNYAEHFTNYRTYMELKDNLSQSQIFNNMSTGEKNEIMNSIINVLQPAMMVSDAVA
GNSINEVAARVSHCLNLTGPSLTVNSACSSSLSALHLACESIRSGESKMAIAGGVNLNIT
PTTFVGLSRVQALSKTGVCYPFDSRSDGMVLSEGASAVLLKPLEDAIRDKDNIMAVIKGS
SINNDGHSQGITAPRPQGQAEAIRKAYLRANIDPATVSYVETHGTGTPLGDPIEVEGMTK
AFRSFTAEKQFCAIGSVKSSIGHMLSASGITSLIKVLLALKNKKIPHTVNYDEATTNSNI
DFANSPFYVASKEAKEWRGNGQIPLRAGVNGFGFGGTNVHVILEEAQKESNCECEDEKSP
YLLQLTGRNQNVIKTIAANLKTNLEQQEELAVSSICYTINNSQKEFSAKISAMVKSKKHL
LEILTQIENDNITEKIYEGRSNPNRQTEAYLVLDGNIKHIKEDLSVRFVAFNDAYKECMD
RCERFKNITKEEMASFETFASQYALGVLFSKFEVKLYGIIAERIGIVAASVLTGIISLDQ
ALEHIFSSSIIIDEERNKIYENKIYVSCPILTPSGVIESEFNIFSHDEKCIKSLNGFVNK
NQVVIYLGSYDEIKTKDFYDEKLINWVEIDINNSPVESIIKAFAKLYTLGVRYNPNKFFN
YNIKKVTLSTYPFENENYKISVQKEPVYAESDQLKKIEPKGLLKIEKNHTLSDIQKQDIC
KQLINDIKM
>G6FSF5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Fischerella thermalis JSC-11|TrEMBL
MEEIAIIGISGRFPGAKNIEKFWQNLRSGVESISLFTDEELIAAGIEPGLLNNSNYVKAG
AILEDIDLFDAAFFGFNPKEAEITDPQHRLFLECAWEALENAGYDSQRCESRIGVYAGAS
LNNYLSFNINRDQIGSANSFQKLIGNDKDFLTTRVSYKLNLSGPSVTIQTACSTSLVAIT
LACQSLLNYQCDMTLAGGVSIRVPQKTGYLYQEGGILSPDGHCRAFDAKAQGTIIGNGVG
VVVLKRLADAIADGDHIYAVIKAAAINNDGYSKIGYTAPSVNGQAEVIAEALALAGVEPE
SISYIEAHGTGTNLGDPIEINALTNVFRDYTDKKGFCAIGSVKTNIGHLDAAAGVAGVIK
TALALQHKLIPPSLNFQQPNPEIDFANSPFYVNTKPTQWQAEKTPRRAGVSSLGIGGTNA
HVILEEAPVAETCHGTSLQSRPWQLLLLSAKTESALENATQNLAHHLSEHPQENLANVAY
TLQVGRREFDYRRILVCQDIADAVTTLNRHDVQRVLTHFQEPVERPIAFMFPGQGAQYVE
MGKELYQTEVIFREHLDRCCLMLKPLLGFDLRSLFYPHENQAQAAEKLKQTSIAQSALFV
IEYALAQLWMSWGISPSAMIGHSIGEYVAACLAGVMSLEEALTLVAMRGRLMQQLPTGAM
LSVALPEEEVKTLLHQELSLAASNAPHLCVVSGSHDAVNTFEAQLQAKGVECRRLHTSHP
FHSQMMEPILESFITEVKKVKLYPPKIPFISNVTGTWITPEEATDPNYWAKHLRFPVRFS
AGISQLLQQPNRILLEVGPGRTLCTLAKQHSHQAIGQVVLPSLRHPQDKQSDVAFILNIL
GRLWLAGVTINWSGFYAHEQRQRVPLPTYPFERQRYWIEPQLTAEKSGQAESKLGKKPNI
ADWFYVPSWKQIPLVKTGEKRSTCYLVFVDECTIGSQIVQHLQQTGQDAIAVLVGAEFSQ
VNHNTYTINPTQKDDYYTLLQTIHQQGKIPETIIHFWSLTHLIHQSLETIQNHGFWSLIY
LAQALGQQNISDSKIQLFVVSNHLYDVTGNEELLPAKATILGPCKVIPQEYPGIKCRQID
VVLPTSRIDNLVQELLAEITAESNESIIAYRNHHRWVQVFEPITLEKPTSRKTRLRQKGV
YLITGGTGGIGLEIAKYLAQTVQAKLILIGRSQLPAKEHWQQWLATHDTSDHTHHKIQKL
QELETLGAEVLILPADVTNYEQMQSAVAQSLENFGEIHGVIHAAGVAGSGIVQLKTLEIV
NSVFAPKLQGTLVLNEVLQDINLDFLVLCSSLSSIYGGFGQVDYCAANAFLDKFAHFNTS
KNGKLTLAINWDTWQEVGMAVNTAVPEELKKWRSETLKNGLLPTEAVEAFERILANPLPQ
ILVSTQELQLVIDQFNQFLSSSFLNSKSENFTHLSGTRHARTLQETTYVAPRNEIEQSIA
NIWEELIGIDKVGIYDKFFELGGHSLLAVQTISRLRETFQVDLPLRTLLFEAPTVAELAI
VIAEKQPKAEELKEIEQILAEVENLSLDEIKQQLAQESQASGLCH
>A0A2C9ELS6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudomonas protegens (strain DSM 19095 / LMG 27888 / CFBP 6595 / CHA0)|TrEMBL
MDARAPMDFEPIAIIGSGCRFAKGASTPEAFWELLRAGTDFVGPVPAERWDTAAIYDESA
AETGTTYSKVGAFLEHIDRFDAHYFGISASEAKEMDPQQRLLLEVACESVARAGLTREQL
KGSRTAVYVGMLGMDYLALHSREAGIEQINPYYAAGKEFSFAAGRIAYHLGVHGPAMTVT
TACSSSLVAMHLACRALQAGEADMALAGGVNLMLAPDLTIYMSQIRAISPSGRCRVFDAA
ADGIVRGEGCGVTVLKRLADALRDGDPIQAVIRGSAINQDGASAGQTVPNANAQAAVISQ
ALKVAGLSVDDIDYVEAHGTGTPLGDPIELSSLDSAFQGRERPLWVGSVKANMGHLDAAA
GMASVIKTMMVLKHAEVPAQLHLAQLNPLVDWKRSRLAVPTAIESLPDRPRLAGISGFGL
SGTNVHMILEDASAYRQAQPQQERSAQGRPWVLPVSARSAQAVVEQARAYAVHLPQQDDG
QLQAFVASAIHRRDHFPYRSAVVGANAAQLKSQLEQLPAPTLACTTDEEDRRGPVLVFTG
QGAQWVGMGRDLLEREPAFLAMIRRCDQALAQWASWSVEAELRSDASGSRLHLTEFAQPC
IFAIQVAISECLRQWGVIPAAVVGHSMGEVAAAYCAGALDLESAVRVIHHRAQAMKDTLG
QGRMLVVGLPAPTLQSRLANNPQLELSVVNSRNSCVVSGSPQAVQALDQQLRDEGIFTYL
MSAEYAFHSRQMDECLTQIRAGLEDLPVFAAHTPWISTSAMPEEPILADADYWARNARGI
VRFDRAIEQLIEQGHRLFVEIGPHTVLAASINQALADKGTQGLVCGALHKQGDAALELAS
IVARLYEWGAGPDWQAFQPREAALELPAYPWQQERFWFAPAPRPQPAGLVSQLRAQVLVY
DAQGNLCAQANDVALSVPQLAQAAVPAPAKVPAAAQPVGDVRAQIGALLTQIIGVACADP
DPDRGFFELGLSSISLVEFKRMLERQFALKLSATVGFDYPTINRLGQYLEGLLSREPAST
PVTVDAGAPDAAGSVAVVAMACRFPQADSPEALWKLMLEQTDTVGPVPPSRLAGAKPEET
FPRFASLIQRPEGFDEAFFRISPKEARSMDPQQRLLLMVAWEALERAGIPQEKLLEQRVG
VFVGANSHDYETRVLGSAQGVDAHYGTGSSFSAICGRLSHFLGVRGPSLTVDTACSSSLT
AIHLACNSLRAAECDIAIVGGVNVIASASIFQSMGQAGALAPDGISKAFDDSADGYGRGE
GCGVVILKRQAQAERERDPIVATILGSAVNHDGACAGLTVPNGPAQEALISEALANAGVH
PGQVSYVEAHGTGTVLGDPIELNALHNAYRQASPDSPPLTVASVKANIGHLEAAAGIASL
IKACLVVEHGRIAPQAHLQRANTRVDWAAMNLKLAHQAMDWPGRPESRVAGVSAFGFTGT
NVHVLLKGYTAPATAPLPPATAPVALCLSAATPAALAELAQRYVSFLGATEHCPQTICYN
ALVRRTAFKERLVVHGQDCRELAQALQAWLAGSPIANDRKPAAGEPWATLAEAFGRCAQP
PGPERLPDGCQAIGLPTYPWQLNDYWIDAGQPATAVQPARAASGHPCLQGLVRPAAQLWY
WSGALAPQAGHYDPLGEQGYRVKTHLLLDAVLQAVRETPRGVQQIRDLQIAQLRLRGEQH
LTSHLSIHLTQAPDACFELALQGAGDERRQVCMSGTLVDCAAQLQEETLCGVSMLDEPSP
PAPDVGLCPWSGCAATGGQRALYRFAHSLTAAERQTQLLASVVELFEGAHAAALVGFSGL
QVWADLPAQVWIVLAGHDADKPDSLQVVDARGCQLALFEGPQFGHPGSWYLPDLQTAPLD
LPMIARQWQDYPMPGEGARQREGYWMVLAWSTAEVQPLAAAFAAEQRPVEVIELHAGQQP
LARKLSSALRGAVADPSCLGVIVAGVEAQEADGLGISLVASAALVQAFAGAIASVGTPAK
PVWFALHASDAASPAMAAVQATWQGAAHIFALEQPAWWGGLVTLQGSDRRSYASLCRLLH
GQPGHDHFAISGARVEVQYLVEDQADPLQRLEPPALNGTVVLHAVPGSDLETVLTALGQR
GVQRVLLLCEAPGQLHMPERMPEAMAISSLSDLSRENLADTFATLRAQDRIAGFIHLDLD
WRTVALKEPEFVVRMQEGVRPLEVLQQVHQLIDDPEAFFLILGSVSSLLGGAGFARSAIA
DAYALWVHAQRRRQGLNCQLLHLTQSEQELEQDAAARTAMQGSGLQPLQRSQIVQAIARV
LGGQGQCGLLNVDWQQLKGLYLSVLPWPLLEHLGAADSAADQRLAELIGLPPLQQRRAMQ
ALVCEVVGQVFGVADGLELDVRKGFFDMGMSSVMSLDLRSRLGRALSIDLPSTFGFEYTS
IEQVTDYLMGQLLAPETREPVAAPEPVSPASRHQDLHELSRAELIGALEDELRDIANY
>A0A086Q411|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii VAND|TrEMBL
PVSRLFGRVEFSEPAIPFISTVLGRLAVGSELSDALYWSEQITKPVRFREAVVAAFGGAV
AGLSAVEHMAEVLLSLKRMGLDTSRVCGLGAISSLETLQNLVQGGTWAGMLVVSGLWATV
SAVESLTETAHILRHYACLSTEIEVPVLAVVTRGAQRSVVSPETFGQRERPTLESVPQQN
QVFGHLEDEVPVHAGLLAFCRTLRLEMGRCCRRFKPFLYFDTDRLHPRQSKESLDYHLGA
VLKWLSRNDVPASFSEQIRPDSDTLREWDIVIRKQSYFVPRVAPVLLKQPSTTAAGRIQK
AKSYIVTGGLGGIGIVVASWLLRQGAGRIFLWSRRGVPTDDVKETNQWCELNAAMETGRI
QTVSCDVSEIEQVRHSIVLAVTDSILGGIFHCAGTEGKGKLQDVSQQDIADVNALQEALK
IKLPASLLVEYACLKDIIQFIMENCFSDAARSTSDLVPLVTREPAANDQGFAVVGMGCRI
PKNATTTEEFWDMLLHEIDAVCEIPMDRFNIDAFYDPDPEQDKCYTREAALLDHPDFFDN
TFFNLSDQEVLAIDPQQRVLLEVAYEALFEAGFTKEALLGKDFGVFCAAYNNDFQFTNLT
QGKATMCVFDKGEGRGRIPSLGEAAGYPEPGGFMCFIPNRISYSFGLTGPSIGIDAACAS
SLVAFDAAVTKLKRGACSGALVGGVNIILSPTFFLGGCKAHQFSRAGRCKTFDCNADGLV
RGEGCGAAFLLPLDAARETGAFVHAVVRGSATCHYGRSSQITSPNTRALTRVLRLSLQDA
STAPSLVRYYEAHGTATVLGDVIEMSAVKDVFQTGRNAAAPLHMGTVHNNIGHLDAAAGI
VAFLKTVLCLKHRFVPANIHFKSLHPDIHGIDTQLIKYTRESHSIMTDDVATGVRKTIFG
ANLAYGMGGSVAAIITESGDEEADRRSLKAAPRHVWNHRRFPLNTQKFVYLMGAMGQISM
DDMPTPQSDVIHVMKRLSATALNVAFMRKLSPSTCAAGSIRSVFLTGATGFIGSQVLFHL
LQVKRQDPKLGTEDKKLTIYCLVRARDRAHGIYRIRDSLVGRGIEWKHEFDQQVIPVIGN
LEEGENMGLGPKQMQYLEQTVDAVYHAADNVNFAAPYDALRKSNVLSLIPILKLCTTYVA
KPLHLVSNFAHHLQYFAGFSEDLNIAVDETVSPPLSPASIDRLEQQMPAGIIGYPWTKWA
VEEIIGRMKDVLHERCEEEGQRVSMEESEKKDILSKFQVTVYRLPNSCVYYNNGYTNFAN
ASLSLVLASAQERMIPPGVLPVGAPFLTTPVDLITGILVKLSMTERKRHHVYHLVSLRVA
RRKHVVQAIKWLFPDSVECTADELFRRIDENKENSPAHPLRAAMRFWRRYWYSSDTDRDS
PFPVAVNNVEDDLPGVMATFPSLADTWLRMASYCVKNYHMVRHPFTLAISFERLKKAIAG
ITKQRIDELALPSQTQELLNETCSTEDTTDIAAVKALVEHANLRKYDDCAVSDVPDPRAR
A
>A0A395L421|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ensifer sp. M14|TrEMBL
MAVEIIGRACLAPGAESPSALFKLLRQGKCTVTSIPSDRWDVARFWHPVMGTQGKTYSFA
AGVLDQLYDFDPAVFGMSQREAMYMDPQQRVLLQLAWRALEDANISTTSLHGENVGVYIG
ASSLDHANLTVEDPAAAGPYFMTGNTLSIVSNRISHIFGLSGPSMTVDTACSSSLVALDQ
AMRALNAGEIDTAIVGGVNILAHPLPFVGFAQARMLSPEGLCRAYDNDGAGYVRAEGGVV
FVLRRSDRARKEKDRSYARIVASGVNSAGRTNGISLPSREAQANLLRAIYEGNGIDANQV
AFVEGHGTGTKVGDPAEVWSIGTVIGANRRAPVPIGSIKSNIGHTEPASGLFGMMKAILA
LENNYLPASLHFDTPNEHIDFDGLNVRVTASPIELLRGKRARLAGINSFGFGGANAHVVI
SDPEPVSEDKINNPPSSGHVFLASAHTASSLEALLKDYKTRFANASKGEIRSMVAASGAN
RTHMRYRFAARSDHPEDIVRAIASHVEKPGSDIGEVGEAVTRDAKVAFVFSGNGSQWAGM
GVEAFRENLHFRQCFTSVSALFKFHSDISLIELLTDPDLDKKLSDTKIAQPLLFAVQAAL
SDSLVAMGIKPVAVFGHSVGEIAAAYAAGALSMVDAVSIVAKRSLHQDLLAGHGTMAAVM
LGEDAARAFAEARGLDELCVAAVNAHNSVTISGPAHQISAFRDAARKAKIPVQILDINYP
FHHPIIDRAKDAFLSDIPDIAPRRAEVTYLSTVTGAALDGTQLDPDYWWKNVREPVRFQA
AAEAAIEFGCRLFVEISPRPILSSYVKETIKQAASPGMVVPTLLRDVGETGQDPISAAMA
RAVAHGAIVDTTRVFGKRNAAISLPSLPFEPVELRPAATTDATDLFGRTAKPYRLTGWRS
DPNSGSWKNHIDAPLFPDLAEHVVDGKAILPGSGFIEIAVAAAQQFYGTDEVEITNLEIV
RPLELSDSRIMELSTVLSPETGDIEIRSRERLSEDDWAVHAVARSRKPLPNEERHLPSFA
GMQKTATVAPAKAYDTARQFGLDYGPRFQLLAKAAAYDDRFVDVELKSPDKSGHPLITYA
LNPISVDATFHGLVALFDRFTGDKSGAPYIPVRFGSVRVVNAGKPIARATIEIERVSANS
IKAKFHFFDKSGGPVAYFEDCRFRRTYLRKHKTLDALSFHYETVLSEALLPTVETGVRAP
VTLGVTAAADTGIDNTTLLFNAAIYRACQEIALKLGKGRSIVRSDSLPGDFAFQCFLASC
LYVLEDAGLCEHKDGVWTVAQEFSLPSVSEILRELYGERPDRAVEAVLINNAYAEALARL
DVLLAAPAGGEAETVANSSFISDATLDHQAVHSEASRQRMALVLDAVEAALRAQPAGMRL
RIVELGSVSAGFTRRLSALSAKHGASLSVVEPRDNAQRGLELAFENDAHVRILKKGELAT
QAPFDLAISASDRLYGLIEDDIDVRAALRSTLRRTGGLVAAVGAPSLFNDFALGLSDGWF
ARSQAAEFPIGNLAAVPHWQKCLVDLDLREIDVTDRECASGNIIVLEARGVETPVPAETG
ADAAVAAVGTYLLLQVGVRQKTQPSAGAVPVNLTGDTSTDTALLSDAIEAFGDRPVRAVF
LSSPAPKSRTDDSASLQAQVLALSAVAEVLRQHVGDTDPNGDARPRLVLVAPDGAPVAAR
VSGTTAVSFGTNAGLWAFARVLQNEYEFLDVHALDLAADSATSDEQKTAAALPLLAVSGT
NREWLLEGPNGSLSEIRAVSGPTDSAHGSTASFDAATIRQRVASQVGSIVWEESNVPTAG
PGDVVVKVAATGLNFRDVMWAMGLLPEEALEDGFAGATIGMELSGHVVAVGQGVDDLSVG
DAVMAIASAAFSTHAVVSRAGVARLPHSVSPVAAATVPVAFLTAYYAMVELGRIQAGETI
LIHGAAGGVGLAALQVAKLKGARVIATAGTREKRRFLSMLGADHVFDSRSLGFVNDVRAV
TGGEGVDLVLNSLFAEAMEQSLALVKPFGRFLELGKRDYYADSKIGLRPFRRNISYFGID
ADQLLVNAPALTKRIFTEIGALFEDGKLTPLPYRAFDFDEIGNAFRLMQNAGHIGKIVVL
PPVAGKHQVATRPRGGVKIDPEGMHLVVGGIGGFGLAAANWLADKGAKNIALCSRRGLAD
AETTAMIELWAKAGIAATVHACDITDATAADSLLTELRSIAPLRSIVHAAMVLDDALISN
LNRERNRPVIDTKAKGAAVLDQLTRGDALDNFILFSSATTLVGNPGQANYVAANGYLEGL
ARARRAEGLAGLAVGFGAIADKGYLVQNTDVNDLLAKRIGKTALKAQTALDMVESHLAGD
PGTVDAAVVMISEIDWSAARNLPVARNALFEVILRSADQHSSGGEGTKMDLVAMIEGKSA
QEAEDILFDLVAGEIAAILRVSKDTVTRSKVLKEIGLDSLMAVELGMSFQQNTGFDMPLS
GVADNTTVGDVARKLYEKVSKRDQGDDSDGADDKLVTELAQRHIGTAKEKAQSQ
>A0A1Q2ZE06|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MEKREKLLDYLKWVTADLHRAEARIAELESLPREPIAIIGMSCRYPGGVTSPEELWHLVT
NGVDAIGELPSDRGWDVQGSYDSDPDTPGKFYNRGGGFLADVKGFDAAFFGTSPREALAM
DPQHRLLLETSWEAIERAGIDPRSLRGSDTGVFGGVLYNGYGAGVDDPGLGIEGYLMTGT
SSSVAIGRISYTLGLQGPAVTLDTACSSSPVALHLAAQSLLRDESSLALAGGAMVMANPA
FFVEFSRQRGLSPDGRCKAFSSAADGMGFAEGVGMVLLERLSNARRNGHPVLAVIRGSAM
NQDGASNGLTAPNGTAQQRVIRQALANAGLTPSDIDLVEAHGTGTRLGDPIEAQALLATY
GQAHTPQRPVRLGTLKSNIGHAQTAAGVGGVIKTVMALRHGVMPRTLHADEPTSDVDWSA
GTVELLTEALPWPDAGRPRRAAVSAFGVSGTNTHIVLEQAPEDEPAPADTGRTLPVVPWL
LSARTPEALRAQAARLVSFVESSGEVEARDVAYSLATGRTAFPHRAAVLGKDVGELVAGV
RAVADGGPGATTLHGVAGEGQTAFLFTGQGAQQAGMGRELAETFPVFASAFEEVCDGFAG
LLPGSLKDVVFGGAGLDRTEWTQPALFAYEVALFRLLASWGVTPDYVTGHSVGELTAAHV
AGVLALPDACALVAARARLMQALPEGGAMLAVQAAEDEVLPLLAGRGAEVGIAAVNGPRS
VVLSGSGDAVSSLARTLSDRGHKVSRLKVSHAFHSPLMEPMLDEFAEVAGRLAFGTPAVR
MAAPASEVSTPDYWIGHVRRPVRFADQVRRLRDQGVTRFVEVGPDGVLAAMGRECVDAGF
VALQRRGRPEVRTLLTGLAQAHVLGTGIDWRAVFAGTGSRRIDLPTYPFQRRPYWLAPAQ
AGTSSPVAGTSEWGYEDRWRPWEAPAAREDGTLLVVVPTGVPAEWKEMVASGLGAAVPVE
VDPAGGEQAVVDAVAGAQVREVTAVVSLLALGDGVAGSVPVGLAGTVWLVRALAGAGVTA
PLWCLTRGAVAVGTEDEVCSPEQTALWGLGRATALELPHRWGGLVDLPKRIDQEVAGRLR
SVVSGGPGGEDQVAIRPAGVFARRLVRSAPGVGRGDRTWAMRGTVLITGGTGALGAHMAR
WAVARGAEHVVLVSRRGMAADGAAGLRAQLEEAGARVTVAACDAADRAGLTAVLAAIPGE
FPLTAVVHAAGVGDGDAPVGEITADGLAGLWRAKAGSAWLLHELTGELGLDLEAFVMFSS
GASSWGSAGSPGYAAANAFLDGLAGHRRSRGLAATSIAWGTWSSDGLASEELLEHLARIG
LRPMDPEPAITALEQALLDGHTLLTVTDTDWRRFVPAFTAHRPSPLLADLTEARDTFADD
ATPPLLQRLAGLSHGEQHRQLLHHTHTELAATLGHDDLTGIDPGHPFKDLGLDSLTAVEL
SNRLSTATGVRLSPSALFDHENLTTLVEHLHSELMGGSLAPAQAAVDFDAEIRLAADVVP
PAETAPTDPGTVFLTGATGFVGAFLLRDLMRSTGAKVHCLVRAEDEATAFERLRATLTGY
RLWDEIDAKRLAVVVGDLARPGLGLAPETSDALARTVDVIYHVGADVNWLKPYSALKAAN
VTGTEEVLRLATRYRSVPVHYLSSTGVFARRAPHGGALAPNDPSGPGSELPTGYTQSKYV
AERMIDIARSRGLPVTVYRADVVCGDQLNGACQTRDFIWLSLKGGIQAGALPSNADALIG
MVPVDYVTAAMVRLSRTRSAAGRTFHLQNRKPAGFREMAARLRASGYRLDDVPWADFVAA
VRADRDNALFPVIDVFSVFMKLGEASHVPVDVGGTEQALAGSGITCPEITPELLGLYARF
FAESGYFPAFPDDGRK
>N0CTQ6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces fulvissimus DSM 40593|TrEMBL
MTNQSHFPRATERGGHEGPIAVVGVSCRLPGADSPAAFWELLSTGSDAITGVPEGRWRAA
SGAEAPEGTEPGMRRGGFLDSVDTFDAAFFGISPREAVAMDPQQRLVLELAWEALEDAAV
RPAALRGSRTAVFVGTLRDDYAALLYQYGDRAITQHSMAGINRGVIANRVSYHLGLHGPS
LTVDSAQSSSLVAVHLACESLRAGECDTAIAAGVNLNILAEGAVTEERFGGLSPDGTTYA
FDARANGFVRGEGGAVVVLKPLARAVADGDRIYGVVRGSAVNNDGATSGLTVPGQSSQER
VLREAYAKAGVDPAAVQYVELHGTGTPVGDPIEAAALGAVLGAGRPAQAPLRVGSAKTNV
GHLEGAAGIVGLLKALLALRHRRLPASLNFASPGPRIPLPELGLDVQRELTEWPAPEREL
VAGVSSFGMGGTNAHVVLTEGPARVADDPSSDAAGSLAGDAPSDAADRAAGPVPLVLSGR
SEQALRAQAGALHGLLAREDAPDPADVGRSLATTRTVFEHRAVVLTGAGDGAGAVAALAA
LAALAEGTVSADVVTGAPAPGRLAFVFTGQGAQRTGMGLELYEAHPAFAAAFDAVCAELD
PLLERPLREVIASGDGLDETGFTQPALFAVEVALYRLVESWGVVPELVAGHSIGEIAAAH
VAGVLDLGDAARLVAARGRLMQELPPGGAMVAVEATEAEVEAELREVIASLPAQDGLVGI
GAVNGPRSVVVSGAEEAVLAVAGRLREQGRRTKRLPVSHAFHSPLMEPALDAFRAVVDGL
TLRAPNIDAVSSVTGEAVTGAWSEPGYWVDQIRRPVRFLDTVRALEDAGATTLFELGPDG
VCSAMADDCVRDAGAVVAVPALRRGRPEPRTLLAALATVFTRGAEVDWAAVQEGRGGRRV
ELPTYAFQRERYWISGTARTAEPESVPEPVAPQRSGAQAGGVATGADVGTLVGQLAAAVL
EYAPGRPVPPHTPFRELGFDSLMSVELRGRLSEATGLRLPTGLLFDHPTPAALTAHLKAA
LTGTGPAAGAAPAVGGSDEPIAIIGMACRYPGGVTSPEDLWRLVADGTDAVSGFPTDRGW
DSDLYDSDPGRSGHSTVREGGFLADAARFDNAFFGISPREALAMDPQQRLLLETAWEAVE
RAGLDADELRGSRTGVFVGATTLDYGPRMQDAPDSVEGHLLTGTTPSVMSGRIAYQLGLV
GPAVTVDTACSSSLTALHLAVRSLRSGESSFAIAGGATVMSSPGMFVEFSRQRGLAGDGR
SKSFAASADGTSWAEGVGLLVVERLSDARRNGHRVLAVVRGTAINQDGASNGLTAPNGPA
QQQVIRQALADAGLVTADVDAVEAHGTGTKLGDPIEAEALLATYGQHRGERAPVLLGSLK
SNIGHAQAAAGVGGVIKMVQAMRHGVLPRTLHVDEPTPMADWESGAVELLTERTDWPATG
RPRRAAVSSFGISGTNAHVVLEQAAAEDAAEVPEPWPLAAPAPWPLSAHDGPALREQAAQ
IREFVGAGTSRPADIGFSLATTRTALPHRAAVVAATREELLAGLGALAEGREDDAVVTGS
AAHAGRTAFLFTGQGAQRAGMGRELYAAHPVFAQALDEVCAALDAHLELPLRDVMFADEE
ESAESGADLSPLHRTAYTQPALFAIEVALFRLAGHHGLTPDLLAGHSIGELAAAHCAGVL
SLADAARLVAARGRLMESARAGGAMIALEAQESELTDLLAEFDGRLSVAAVNGPASVVVS
GDQDAAEAVAERIRALGRRTRRLQVSHAFHSPHMDDVLAEFRAVAAGLTFHEPTVPLVST
VTGRLATAAELTSPDYWTGQIRGTVRFLDAVRELEAHGATVFVELGPDAVLAPLTRSGVT
GEAAATVALLRAGRPEAATLALGLAAARAHGAPLDGASFFPGGRPADLPTYPFQREHYWL
APRSPGDARSFGLAPAEHPLLSTAVDLAGREDLVLSGVLSTATHPWLADHVVGGGVLVPA
TAFVELALAAGERVGIDRVGDLTLEAPLLLPADAAVRVQVAVGPPAADGSRPFGVHARPG
HAAADDEPWVRHVSGVLGGPGVSGGPGEELRQWPPAGAVAEPLEGVYDRLADLGYAYGPA
FRGLTKLWRSGDDLFAEVRLPAEQHAHADRFGVHPALLDAVLHPLVLHAADAAGDGAVRL
PFAWTGAQLYATGATELRVRIAPVGPDTFALTLADATGAAVAAVESLVLRAVPRSGLAGA
TQGGGEHLYAVEWTALPASAPTGAASVLEVRDGVLPDPGALDGVDVLVLRTPAPGGADDD
PVRAAHRTAAHVLDVVQRFLADERYADVPLAVVTRGAVAVRDGEEITGLADAPVWGLVRA
VQAEHPGRLVLVDADGSDDLPTLTTDEPQFAVREGLLLAPRLVRATAPAPADGPLTAPSA
LDPDGTVLITGGTGGLGALFARHLVTRHGVRHLLLASRSGERAAGVPALRSALEELGAEV
TVAACDVADRDQVAALLGTVPAEHPLTGIVHTAGLLDDATVEALTPERLAAVLRPKADAA
WHLHDLTRGLNLAAFVLFSSVSGLTGTAGQANYAAANTFLDALAAHRHALGLAATSLAWG
LWDATHGMGSTLGEADLARWRRAGIRPLTPEQGLALFDRALLDGQPLRAPVAFDLAALRA
RTEPPAALLRGLVKTAPRRAAAQAGGGDGGWAQLTAALPVDERADAVLALVRDTVAGVLG
HADATALDPRRAFNETGFDSLAGVELRNRLNTATGIRLPATVVFDHPSPQALAEHLITLV
GPAPKVSAPAAVVRAADRDEPIAIVGMACRYPGGVTSPDDLWRLVADEVDAISEFPVNRG
WDLEKLYDPDPDHTGTSYVRHGGFLHEADRFDREFFGISPREATATDPQHRLLLETAWET
MESAGLDPAALRGSRTGVFTGAMYDDYVSRLTSSPEEYEGFLLAGNLSSVVSGRLSYTYG
FEGPAVTVDTACSSSLVALHLAANALRNGECDLALAGGVTVMAGPSVFVEFSRQRGLSAD
GRCRSFAADADGTGWSEGVGLLLVERLSDAKKNGHQVLAVLRGSAVNQDGASNGLTAPNG
PSQERVIRQALADAGLAPADVDAVEAHGTGTKLGDPIEAQALLATYGQDRPAEQPLLMGS
LKSNIGHAQAAAGVGGVIKMVQAMRHGTLPRTLHLDEPTPMVDWESGAVELLTERTQWPE
TGRPRRAAVSSFGISGTNAHVIIEQGLPSAPEPAASGTDGPGAVPWLVSARGEDALRAQA
GRLHARLAEQPGPSVADIGLSLATTRAVHSHTAAVVGSGRDQLMDALGALSRGEPSPAVV
RGPGSGVHRGRTAFLLTGQGAQRLGMGRELYAASPVFAAALDAVCEHLDRELVRPLKQVL
FAPEGSADSALIDQTAFTQAALFAVETALFRLAEHHGLTPDFLLGHSIGEVTAAHLAGVL
DLPDACVLVAERGRLMQAAREGGAMAAVEAAEDEVRATLTPYGDAVAVAGVNGPRSTVIS
GDAPAVDEVMALWRARGSRVKRLPVSHAFHSPHMEEILDEFRQVAEGLTFHAPRIPVVSN
VTGVLGTAEDLASPEYWARHIREAVRFMDGVRHLAERGVTEWLELGPDGVLTALVRECLD
EERTGALAPALRRGRPEDVVFASALAQLALRGAPVRWDTVFPGARRVELPGYAFQHRRYW
LDAPATVGDAAGFGLAAAGHPLLGASVALADRDEHVLTGRLSRHSHPWLTAHAVAGTVLV
PATGLLELALRAAEQAGASGVEELTLAAPLVLAEHGGVQLQVSVSAPEADGGRAVRVHSR
PDGGTDDEPWTLHAHGRLTAGDGHGGGSGAGDGLTAWPPPGATERDLSGAYDRLAAVDYD
YGTAFQNLRRLWTGPAGELYAEVALGDELRGEAPRFTVHPALLDAALHPLLPGVAAEDGR
SWLPFSWSGVTVHATGPASLRVRLTPVPEGDADSPVYALTVADGTGAPVASVDALTLRPL
SADAVRAAGGGTADGLLRVEWSALSGAGTPVAGSDASAWAVIGSADSLRGAGGTAYPALG
DLGAALDAGGALPPVVVLPLHAVSAPAEGAAVPEAARAALHRVLAVVQEWLADDRFAGSR
LAVVTRGAVATAAGQETDLVHAPVWGLLRSAQTESPDRIVLIDLDRDDRDGKDSNKADEA
RHLARALDSVEPQLALREGELLVPRLARTAPPQDGGTAPGWGDGTVLVTGATGALGAVLA
RHLVRQHGVRHLLLVSRRGANAPGSAELSAELAESGAEVTVAACDVADRDQVAALLGTVP
AEHPLTGVVHTAGVLDDTTVASLTPERLDAVLRPKTDAAWHLHELTRDLDLSAFVLYSSV
AGLLGTAGQANYAAGNTFLDVLAAHRRALGLPGTSLAWGLWAEASALSGHLSDADLRRLA
RSGLRPLSTDDAMALFDAAPGTGEALLAVTRLDTAALRASGEAPPALLRGLVRTSPKRAA
NVSAGAGSGPGLAERLAAARPADRDVMLTDLVRGRVAAVLGHPDPTEIAPGRALQELGFD
SLTAVELRNQLAAETGLRLPTTIAFDQPTPGALATYLRERLAVDEMTADEPLLAELARLR
PAVEAAAGDADAHGRIVTRLRELLDAADAAGRPAPAEDDTTDDLDAATDEELFALLDERE
>W6VVA8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Rhizobium sp. (strain CF080)|TrEMBL
MTIEIIGRASVAPGANSVRELQRVLSEGLCTITRIPDDRWDSARFWHPAQGIPGKTYTFA
AGVLDDIYAFDPAVFGLSQREAMQMDPQQRVLLNLVWQALEDANLPVSKLAGERVGVYIG
ASSLESGNLLSEDPAAGSPYFMTGNTLSIVSNRISHVFGLKGPSMTIDTACSSSLVALDQ
AVAALERGDIDTAIVGGINLLVHPLSFVGFAQARMLSPEGLCRAYDTNGHGYVRSEGGVA
IVLRRSDRARREGDRSHARLHAVAVNSSGRTNFISLPSREAQAALLRSIYEDGAIDVNRL
AFVEGHGTGTRVGDPAEVWAIGTVIGKKRRAPVPIGSIKTNIGHTEPASGLFGLLKAMIA
LEDNFLPASLHIERVNEDIDFDSLNVRVTTSAVKLLPAKEPRFAGINSFGFGGTNAHVVI
SDPERITPVDPPKGEGALFVASAHTAAALSRLLEDYRNRLSASAPQEARRIIGSTAANRD
ALRHRFAVEAKDSEGVLKAIETHIAGEASQGERGEAPAQAARIAFVFSGNGAQWAGMGVE
AYQESRHFRQCFQSFSALFEYHLGEKLTDVLVAPDLALRLGDTKIAQPLLFAVQASLSDC
LVALGVRPDVVFGHSVGEIAAAYVAKALTAAEAVAIVAKRSRYQDLFAGQGKMAAVVMNE
EAALAFARANGLDEICVAAINAPNSVTISGPTDEIQAFRDAARKAQIVAHVLDINYPFHH
PIIDKAKDAFLADLPQIEPETGTCTFVSTVTGAVQDGQGLDAEYWWHNVREPVMFKAAAQ
AAMDMGCNLFIEISPRPILSNYVGDIAKQNSVPAVVTATLQRETPVPGRDPVAQSFARAV
AHGASPLLSRHSGKRNAFVDLPGLPFEPIDLQSLSTTDEIDVFGRNAKLPYTLLGWRADP
NAAHWKNHIDARLFPDLAEHVVDSRPILPGSGFIEIAVTAAQRYYGTDEVEISNLEIVRP
LELRQDRIVELSTLLSPETGYIEIRSRERLSHDDWTVHAVARSRRPIEAEADVPMARPAG
AQGSVVTSDEAYETAERFGLQYGPCFQLLSKATSFGRTFIEVDLKPAEKPAHPFVEYNLN
PFSVDAAFHGLVALFGALSGNEAGAPYIPVRFGSIRVSGKGGPIAKARIEIERFSGYSIK
VRFQMFDAVGNRVAAFDDCRFRRTSLRRHHTLASVAFHYESVPASLASSRDEQGFDAAHI
FAAAKSRPSDNATLLIDAAIYRACHEIAATVADHRGIVSTRRLPGDTPFRSFLTNCLFIL
EDAGIATSDDGEWHVPRDFTLPPVSEILQEVYREDAGRVAEAVLVNNAYCDALERLSSAS
LHDHSEKGAKADNVSEATLDHVLVHSPLAGRRLSATVEAVETAVAARKGEVRHILKAGST
SVALSRRLATIAAQNGATLTIAEPRESVRRTLELAFEHDVHVTLPEMDKLKALPSADLVV
AAGTQSQKLLSGHDEVRAAIRSAAANGAVLLFADRAPSAFNDFVFGQSDGWFENSQSPEF
PIGQLGAAPQVEDLIGDLGFVRPHVEERGYPEGALLLATASAAVAPQEITSFAPGSPVLL
LAERADAAISFGVVKVDTLGADCGEAELGEAFVRFEDQPLRLIYVAERRGTRDVSVLAED
RLRTSRSLAESLVAYLREAGIFAARPKLAILAPGGSPLAGERTDEANAGLWTFARVLQNE
YDLFDVHLLDAETDLPATSAALTDILSASTNNREWAIVDGRLREIRAATGPFPTSDVLVS
DFPAATIRQLVSSRVDSIAWEACDLPVPDKDEVVIAVEATGLNFRDVMWAMGLLPEEALE
DGFAGATIGMELAGRVVQVGSDVNDLYPGDRVMGIAPAAFSTHVRVRRDGVTKFPDRLNF
AAAATVPVAFLTAYYAMVQLGHIEKGETILIHGAAGGVGLAALQIAKLKGATVIATAGTV
EKRRFLEALGADHIFDSRSLDFVARVRGVTNGEGVDLVLNSLFSEAMERSIELVKPFGRF
LELGKRDYYSDRKIGLRPFRRNISYFGIDADQLLVSLPAVTKKIFTEIGRLFAEGKLAPL
PYRAFSHDEIGSAFRLMQNSGHIGKIVVRPPVAGKDKVLATPGKPLRFSEGGIFLVAGGI
GGFGLSAAEWLVAKGVRRIALCSRRGMADDATHAAIAVWHKKGVHATVHACDITDETATA
VLLELLRSEGPVKGIIHAAMVLDDALLSNLTPERNKPVVDVKVKGAEILHRLTLKDELEL
FLLFSSATTMIGNPGQANYVIANGYLEGLARARRAAGLPALAVGFGAIADTGFLARNSEV
NELLSKRIGKTAMKAREALEQVERYMVADTGSIGAAAAMIAEVDWNAVRMLPISRSAIFE
TVLRHAGSSNATAEGDTIDLEELIRGKSAEEAQQILHTLVAGEIAAILRVTEDTITPDKI
LKEIGLDSLMAMELGMGFQQKTGFDIPLSGVGDDTTVGDVVTRLRERVSTHSDETEDAAP
AENGVVDKLVKSHSVSKQQKAAAH
>Q3M3U2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Trichormus variabilis (strain ATCC 29413 / PCC 7937)|TrEMBL
MVDQQLNPKKSVLQQTPIAIIGMSALFAKAENLQQYWENILAKINCISEVPETAWSLKDY
YDPDPSTPDKTYARAGGFIPEIDFDPLEFGLPPDTLEALDSANLLALVLAKQALKDAGYG
EGKEFNRETTGVILGASGLWKSITPLTARLQYPLWEKVLKNSGLSAEQTEKIIEKMQAAF
VPWTENSFPGMLPNVVAGRITNRLDLGGTNCVVDAACASSLSALKMAISELIEGRCDMML
SGGFDTDNSILNYMCFSKTPAFSKKDYLNPFDATSDGMMVGEGLGMLVLKRLADAERDGD
RIYAVIKGIGTASDGRYKSIYAPRTEGQVRALRRAYEDAGFSPATLGLMEAHGTGTPAGD
FCEFTALNQVLTENQAGRQQIALGSVKSQIGHTKAAAGAASLIKATLALHHKILPPTINV
TQPNPKFKIEESPFYINTETRPWIQNGDTPRRAGVSSFGFGGTDYHVVLEEYTPKFPQGG
DRIHSTAQSILLWADTPQQLSQKCQATLEQLQSDNCGEQYHQLQHHSKTALIPETSARVG
FVATSLEEAQKLLKAAIKQLQIQPQAEAWEHPQGIYYRQTGLSLKGKVVALFPGQGSQYL
NMGREVSLNFPEIQQAYQALDQLMAQDNLPALSDIAFPIPAFNPEVIKQQSQQLQRTENA
QPAIGALSLGLYKILQNVGFKPDFVAGHSFGELTALWAAGVFSDEDYCYLIKARGQAMTV
PQGSHDCDRGTMLAVSGDVAKIKQLIAGMAKVQIANYNAPEQVVLSGSKPEIATLEKVLS
KQGYTVTPLPVSAAFHTPFVHHASQPFAEALNRVTFNTPQIPVYANMTGNAYPTEATAIR
KLLEAHLLNAVQFAQEIENLYAQGGYCFVEIGSRQILTNLVKQTLGDRPHVAIALNPSRQ
KDSDVQLRQGVIQLRVIGLSLKDLDASPRKLPAQKSKSKGLSIKLNATNYISDKTKAAFE
SAFKPEPVVQLASTPLDQVVSDAATVVLDSPAQTFVASTNDEVPITPVSVMEESVSLGEI
YHQSDYQFIISKDETNIMNNSTHNTIAYLFQQFYQHQKEMLQVHEQYVKTQSQSFQAFLQ
LLQQQEVMIPQSSTIAEQTVVVPAPVVQLPKTPAAPIVEPPQTPVVPVAELPKTPVAPVV
EPPQVTPVAEPVHISHIASYLEPRYSAPAPQPTPVVTETASPAANESYISRALMEVVSDK
TGYPTEMLELEMDLEADLGVDSIKRVEIMGTLHESFPQLPKLSPEELAEKRTLAQIVQYL
AGQIMVAEKKIA
>B7PXQ4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ixodes scapularis|TrEMBL
GVMRTKMLECYDIAIIGLSFEFPGTNNLNTLWNGLLDGRCFYHNAGKTGKQVAAWGSVQD
IHGFDYSFFDYSYKEACYIDPQQRLLLQHSWSALENAGYMNINNMPIVGVYASASINRYR
MNNLSGKFNPDFEDEVLLGNTADFLATRIAYKLGLQGPALNIQSGCSSSLSSLHTARIAL
LTNQCDIALVGAVSLSASHDQGYEYLPGGIRSANGQVRAFDIDASGTVFTNGVAVVILKK
LINAKQDGDQIFGIISSSAVNNDGNNKASFTAPTSLAQTQVITKAMKIAKVKPEDFVLIE
THGTGTLLGDIIEFSALQKVFFTENNDSKYCAMQTIKANIGHLDTASGLAGLIKAALVLK
YKKLPPQINFAKANSKLDIANSPFFINTTIQDMSINDSSVKYAGVTALGIGGTNAHVILR
TPTI
>A0A378UZL1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium fortuitum|TrEMBL
MKSVEHPNEQSARFAIVGYAARFPGAPDADGFWDLLKAGRDAISEVPEDRWDVEEFFDPD
PGTPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGTAPTA
LADTNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPSVAV
DTACSSSLVAIHQACQALRLGECDLALAGGANVLLTPATMITFSSAHMLAPDGRCKTFDA
AADGYVRGEGCGVIVIKRLEDALRDGDHIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
DALKRAGLAPSDVGYLEAHGTGTSLGDPIEAQAAGAVLGAGREPDRPLLIGSAKTNIGHL
EAAAGIAGVIKVVLSLENELLPKHLHFQTPSPHIPWDRLAVEVVKEATPWERNGAPRIAG
VSSFGFAGTNAHVILEEAPEPAVANPVERPRPERFDILPLSARTPAALVQLAEQYRSWMS
AHPEATLADVCFTAGVGRAHLEHRAALVVDSRDSAIELLGALADDRPAPGLIRGESHDRP
KTAWLFTGQGSQYAGMARKLFDSEPVFAETVKRCAAAVADVLDKPLLDVIFDLDGPETLR
ETTYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAGVFGLEDGALLMAERG
RLFGSLPAGGRMVAVFTSAERVENLVDEFPALSVAAYNGANTVLSGPAEELERAVAGLTS
DGVRCDWLETSHAFHSALLDPILDEFESYANRFTYQAPQRILIDNRTGAALGRSVKLDGA
YWRRHARQPVEFAKSVRTLADMNCKLLVEIGPRPVLTATALGAWPDQATAPRVIASMRPN
TDDQRQITEALADTYVLGHLPDFSAFRQAHARKLDLPTYPFEHRQYWYRDNREEPNQRQH
AAGPRTQAVRLLEDGRLEELAALLDGAGDDGQTLSVLTKLAAQHNRQRSTQSIADDRYEF
RWEKAVTPLSGASSAETSTWLLIGEESPAVRPLLDVLTSRGQQYRFLALPTTDAAAGQLE
NELRTAAADGSTLHILDIAALDGEPAAKTASSMRTLLRMQHQILAGTRRLFRAAADAGVK
ATIWLVTRGAQHVADADTVAPEQSALWGFGRAAALELPQLWGGLADLSEGTTDEWTAVLN
RVTTSADTGRREDQIAVRDQAVYVPRLVRREDLPNGTPLELRSDATYLVTGGLGSIGLEI
AGHLAAHGARHLVLTSRRDPSEAAAQRIAALSDQHGCDIRAVTADVADAHDVARLLSTVA
AEMPPLAGIVHAAGELGTTPLSELDDAEVDRVFAGKVWGAWHLSEAAAEQKLDFFITTSS
IASVWGGYGQTAYGAANAFLDGLAWRLREQKIPGTSVNFGPWATGMADAESRARLDQRGV
RTLAPADALAGLADAVAVSSAQGPAQGVVARIDWSRFLPLYQQAGRRGFLAELETEAPAE
LSAPTTASGKTQLVERLTNAPVQQRKKLLTDYLRDSVAEVTRVDPSEIREDAGFFDLGMD
SLMAVELRRRIEQGVGAEIPITLVMDHPRISDVSEYLLGDVLGLNEQVKPSSQPASVTAR
TDDPIAIVAVSCRFPGAPNPEAFWELLSGGVDAIREVPEDRFDIDEFYDPDPETAGKTYT
RFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYSPAELRGSRTGIF
AGVAANEYAHLLSSESIDKIEPYFITGNALNAISGRVAFALGFEGPAMAVDTACSSALVA
IHQACQALHSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEG
CGILVLKRLSDAERDGDRICAVIPSSAVNQDGASSGLTVPNGGAQQRLIGTALARAGWTG
GDVDYLEAHGTGTPLGDPIEVQAAAAAYAGSRDTDRPLLMGSVKTNIGHTESASGAAGLI
KVVLSLQHEVLPQSLHFENPSPHIPWDSLPVQVVDKATPWQPNGRPRRAGVSSFGFTGTN
AHVLIEEAPVRPAAAPEEQPADEGSTETQAPDEQVSVLALSARSPEALLALAQRYETWLS
AHPDADLAGVCLTAGTGRSHFEHRAALVVDSIEEARLALADLAENRTRPGVVRGEHTNHP
TTAWLFTGQGSQYPGMARELFDTQPVFAETVTQCADAVKGMLPLPLLDVMFARDAEAAQT
LRHTSYAQPALFAVEMGLARLWQSWGIQPDVVLGHSVGQYAAACVAGVFSLEDGARLMAE
RGRLFGSLPEGGRMVAVFADPKHVEEIANKYPRVSVGAYNGPNTVLSGPGDDLEEIVTQF
GDEGVRCTWLQTSHAFHSELLDPVLDEFEAYAAQVQFAAPTLPLVCNRTGAILTAQNPLD
AQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTSAAVQVWPEHLAAPRAIVSLR
KGIADGRQIADALAAAYVGGHRPDFAAVQRRPAHKVELPTYPFQHRRFWPKTSAITSSGF
DGSGGTGILGAAKDLASGDSIYTSRISVKTQPWLSDHVIYGTVVVPGATYAAMALAAVGT
PAHAKDVFFFEPIILPEKSSREVQLTLHPLETGGEWKFQVHSRPYGERDVDWSLNAEGTV
VSGLGDASEEPTAETDPVDEAIERLERMRPQELFETFADLELAWGPNWSGSLKSLWLGEG
EAIGDILVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVT
LKEKMPRRFYCRAKWHEAELNNETQVFDLEYIDRDGHYLGGVREFTVKRAPREALLRGLG
GDATRLLYTLGWHEVPVPPSDGAAESPSGTWLVAGFDELATKVPGCIPLNRTADPELLGQ
VLTQAAERGMPFAGVVWRAKAPAAHETSTETSARLESEIENLLSAVHTVQGGSLKLPNGL
WIVTERAVATESGEPVDPVQAALWGFGRTTINEEPALRAKLVDSDGSPEAVQALAGLLAT
PVEEPELAVRQGKLLASRLLPWSRSGHLTVPRGGDYVLAPTERGAIDNLRITEKDVPAPD
EGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGVVTQLGEGVTGVEVGQRVYGSM
QGAFSSRFNVPAQFLAPIPDGVSAVEAATIPAAALTVRLSFDWAQLKPGDKVLIHAASGG
VGLAAVQMAQQCGAEVFATASTFKRATLRKLGVKYVYDSRTTDFADQILADTDGAGVDVV
LNSLTSEGFIEATLKATAQNGRFAEIAKRDIWSAEKMAETRPDIAYEIVALDTVMFTEPD
RIRDLLVEISDGLAAAVDSSREHSSVGVWKPLPAEIYPLTEARSAFRRMQQARHIGKIVV
QIPNPLQPKADRSYLITGGLGAIGLHTASYLAQLGAGDIVLTSRREPDADAQRLIEEITE
RYKTRVHVFTADVGEESEVTKLLERIRGEVAPLGGVVHLAGVLDDALLGQQDLDRFRTTL
APKAFGAEYLDRLTKADDLDFFIVSSSVSSLFGSPGQANYATANALLDGLIAQRRAQGLP
ATGINFGPWGQGGMASSEAATANISAQGLIPLDPSAALAALAEVVANGAGQAAVIKANWQ
RAAKVLGSSRPPILDLVLPSAVGEVVGDSEVLKQLLEIPVQQRAGFVTEFLQKEVQNFLR
LASPPAATSRFLDLGTDSLMAIELRNRLHTQFGGKFTLNATAVFDYPTIGGLAEYLVAQL
PDAEAAEAVEASAEATPKSSSDEPHQEAQAEAPAQELPVAEPNQA
>A0A291SHK9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces malaysiensis|TrEMBL
MHADHPERRGPGSSAAPPDGTAPDTGQAPHTGEAPDTGEAGLLDIAVVGMDCRFPGARDP
EEFWRLIRDGVEAVSRFGEAELRAAGVDEDILRHPDFVGAAGVVPDGDTFDADFFGYPPA
EAAALDPQQRIFLECAWRALEDAGHDPAAFPGDIGVFAGQTVSTHQPAPLEALLTSPMDV
FQQMSSNDKDFLPTRVCHKLGLTGPGINVQTACSTSLVAVHMAAQSLLNAECDMVLAGGV
SWTALRSRGYRHQPGGIMSPDGHCRPFDADAAGFVPADGAGVVVLRRLADALADGDRIYA
VLKGSAVNNDGADKVGYTAPGLTGQQRVVAQALTNADVHPDTIGYVEAHGTATRLGDPVE
LSALTRAYRSRGATSTGRCAVGSVKANIGHTDVAAGIAGFLKTVLMLHHGHLPPSVNLSR
VSEELDVADGPFRFAREGEQWKPGEWPRRAAVSAFGIGGTNAHAVLEEAPARPRMPSKRP
WHLITLSARDETALRRSSEECAGFLEAEPEADLGDVCHTLARRHPMRHRLAAAVPDRPTA
LDRLRAGAVTPAVQYGDAGGERPDATVFLFPGGGAHYAGMGRGLYRDEPDFRRALDEGLA
LLPDTELRGRIREALSIRGGHRDGGPDPLADPAVGLPALFLTEMALGELLLARGVRPTVF
LGHSLGEYAAACFAGVFDKEDALSVVVRRGEILADIVGGAMLSVTASEEDVRRRLTPALS
LSVVNGPRMCVVSGPGEAIEAARADFAADGIDCRPVPIATAAHSALVDPALPGFRAFLAD
IRLRPPARHLISNVTGRQAGAEVAEPGYWVDHLRGTVRFAEGLAGLTAERPVFVEVGPGT
TLSTVVRAHPRTARATVAHTLPHPDAPSEDSEVLLGALGRLWVSGVDIDPAALYDGETRA
RQPSVRYPFTRRGFTRPDHDRATPSVAAGNAAGNVPGSGRPGAALYAASWQRTPPPPAPP
PGRALVLTDGSPLGEGVLRWLTERGTAPLVARAGDPGGAFRRDGQEYVLDPGDPEQCAQL
LDAAREEQGSGAPGDGATPLRVLDLWSGRGETGTGNDGGRPEREPVPAGFLALAHALGRS
ATPLELTLVTRAAYGVTGAERPDPLAACLAGAAHVLPLELEHIRLRVADVDPGEWAESGE
SGLRALAGPLAAEKPAERGADPVAAYRGGHRWTRRFLPLARGGETPALVPGGTYVITGGL
GGAGRHLATRLAERHSARLILVGRGAEECDALDGDPRIVVRRADVTDRARMAEVFREART
RFGALDGVVHAAAAPAGGMLQFLTPGALAEGLSAKVAGTYALVDALEAAGERPGFLALFS
SLGSFSGSVGLAAYCAGNAFLDTFAVHASRTLGIPALSLDWDRWQGTGMAREVERRHREL
TKRDLAPGLDPGQAAELFTDALAHLPVHQLAISLRPPDELLAGPGTPAPEPPGRTSPDTA
DGGGTGDGLPADESAGDGCEDERERAVLRIWEETLGVSGIGVDDNFFALGGHSLTAMRIA
QRFNDRFGTTVTAQDLLRSPTVAGLAGLAGDGPEESHE
>A0A379GIK7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Proteus mirabilis|TrEMBL
MIKNNDLPAFMTQVVITEPGGVDKLQLENSPLPSLPPHYMLVKVNAAGVNRPDIFQRQGS
YPPPADASPILGLEIAGEVVKLGEHCTKWAIGDRVCALVAGGGYAEYCLVHEDIALPSQG
LSDIEAAALPENLFTVGQIYFNSVS
>A0A2X2C1Q3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Proteus mirabilis|TrEMBL
MIPYQNIPNDHFEILTRLIHNSLKRANITLEKLRASRTIMYLAGHGPRADFMDYQGFYDK
NDAEDVQYSPQIKSLHAASFAQDELANKLWAEYQLDFPPIPIYCASNSALMAVHIGHNEI
SQDMADIVIVLSWNSLLLQDIAFMDSQGMLVEAHAQPLSKYSDGVTLSDGYAVMILESQQ
QINSRQYLAPAYIYHSVFMQSNAERTMGGTLFNFYTISKVISQLLDLSHYLPSDIGAIFI
HGNGSIISDKAETVAITNIFKQPIPIISYKGQIGYISNCSGIIDLMIIADSLKNNRLIPS
TSHYPIDDGMEVNFLTNQEGVNYSAKPILKIGLGMDGSIIAMLLIANGEQG
>K9W594|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Crinalium epipsammum PCC 9333|TrEMBL
MINQFESNLNLHSDLKNSGLNIQQLETQLHKLEQEKTEPIAIIGMSCRFPGADDPESFWQ
LLRSGTNSASKIPDERWNIKNYYDQDPTVPGKMPLRYGYFLKDIDQFDADFFRISPREAG
AIDPQHRLLLEVSWEALERSGHVPDRLAGSSTGVFIGLTCEDYNDVIQKRPPELNKQHEL
FFVTGVKSYAASGRISYTWGLTGPAMTIDTACSSSSVAIHQACMSLRQRECEMALAGGVN
LILDPTVHVYTYKGRILTLDTHCKVFDASADGYVRAEGCGIVVLKRLSDALADRDNILAV
IRGSGVNQDGASYSFSAPNGKSQQALLNRVLTQTNIHPSEVSYFEAHGTGTAVGDATELT
TIEQVFGLYHSQESPIMVGSCKANIGHPEPASGIASLIKLVLSLQNQEIAPQINIKEINP
CLDWKETAVKIPTQIASWPQSRPHIAALNCFGISGTNSCMLVQEAPELKPIISEWKRPEH
ILVISAKSSSALLQLANRYRQYLSVNQEQSLADICFTANTGRLHLQHRVSIVGASVEEIE
TKLASFYREEEAVGVVSSFISNPEPSKIAFLFTGQGSQYIEMGWELYKTQPTFRKALEQC
DRILQPYLKKSLLDIIYPQPGANSPLDETAYTQPALFAIEYALYCLWQSWGITPAVVMGH
SVGEYVAACVAGVFSLEDGLKLIAARAHLMQQLPKEGIMVALMASQEQITAAIEEYAPKV
SIAAINGLESTVISGEEQAVKAVSAKFEAEGIKIKQLQVSHAFHSPLMKPIITDFLKVAN
EISYSPPKISMVSNLTGNAIANDIATPEYWCRHILSPVNFLAGINTLYKLGYEVFLECGS
KPTLLGMGHQCLPENFGTWLPSLRPGQADWQILLQTLGQLYVSGVKVDWSGFDKDYLRYR
VVLPTYPFQRQRYWLETDNDNNHPPASEQIITQLKSNEVNSKKGKKMLSTKLVKLLEQQR
QELIELLLEETETDFDLQETNSQINRGQNSTKNKGLKQENSLDIAAIQQSNVLQQLKASN
SDRYPLLNNYLQSQMLKILGINQTQLPVNLTLTELGLESLSAMELREKIKQKLGIDIQVK
HLLGGISITHLTEQIISEISWENL
>D8FTZ4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Kamptonema sp. PCC 6506|TrEMBL
MTNSQEYEGVAIVGMVGRFPGATNLDELWSNLCNGVESTTFLTDAELDPSIDSQLKSDPN
YIKAKGIIKDADKFDADFFGINPREAEIIDPQQRIFLEMAWEALEKAGCNPDTYKGLIGV
FAGTGNNTYFANNVSKRPDLIEAIGAFQAMVANEKDFLTTRTSYKLNLKGPSLNIYTACS
TSLVTVSNAFYSLLSYQCDMAIAGGISVTVPQNSGYLYQDGGMFSNDGYTRSFEANAQGT
VFGNGAGVVVLKRLEDAIADRNYIYAVIKGAATNNDGAGKVSFAAPSVDGQAGAIAMAQS
FAGIEPETISYIEAHGTATPLGDPIEIEALTQVFRAQTQKKQFCAIGTIKSNFGHIIAGA
GVAGLIKTALSLHHKLIPPTLHFDKPNPKIDFANSPFYVNATLSEWKAGPTPRRAGVSSF
GVGGTNAHAVLEEAPPVTPSGPSRPRQLLLLSAKTPSALDAATANLREYLQQDPALNLAD
VAYTLKVGRKPFNHRRFAVCSSREDALQVLDSLPPQQSATRQTDGKQRPIAFMFPGQGSQ
YINMGLNLYETEAVFRDTVDECAELLKPHLDLDLRDILYPDGGDAEAATTQLRQTCFTQP
ALFVVEYALAQLWMSWGIQPQATIGHSIGEFVSACLAGVFSLQDALMLVATRGRLIQSLP
TGSMLSVALPAATLEQRLSAEVAIAAINGPSLCVASGATDAIAALESQLASEGITCKHLH
TSHAFHSPMMEPIIDTFANYVRQVELKPPQIPFVSTVTASWITAEQATDCLYWAKHLRQT
VRFAEGVQELWQNDSTLILLEVGPRTTAATLARKQAKDLKKQVVISSLSDTAVNNSEWSA
LLTAVGQLWLAGRAIDWESFYAEETRSLIPLPTYPFERKRYWVEPIASIPSAAEVAVTSA
QKAIDSQPPLPLPITHSSSTMQTSLANQTKSRKERIFPLLQEVIEETSGLEIDIADAATL
FVELGIDSLALTQVGTALQKKFNIKITFRQLLEDFPTLDSLAEFLDGNLPPEVLPAPQET
APILSQTVSESAPPPHQITRQENQNQLPVTNYQLPITNYQVPIANTQPGSLESVVAQQLQ
LMSKQLDLLGNNHSSSLPSALPVSTPQTIQQSPPILSPAPIGNGSSNGTSSAPTSQNSPP
PTEEKKPFGAAARINTQGRELNSQQQAKFEAFVKRYTAKTPSSKKYAQSHRHHLADPRTV
SGFNPTYKEIVYPIVVNRSLGSKLWDLDGNEYLDLTNGFGSNFFGYSAPFIVQAIEEQLK
QGYEIGPQTPLAGEVAELICELTKLERVAFCNTGSEAVLGAMRLARTVTGRNKIAIFSGA
YHGIFDEVIVRGTKKLRSIPASPGIMPEAVENVLIVDYGEPESLEILRNHADELAAIMVE
PVQSRRPDLQPKEFLHELRRITEKSGSAFIMDEVITGFRIHPGGSQAYFGVEADIATYGK
VVGAGLPIGVIAGNRKFMDALDGGFWQYGDSSFPEVGVTYFAGTFVRHPLVLAAAKAALE
YLKQCGPQLQQSLNQKTNKLAADLNGLFEQLQVPFQAKNFGSLFKVIYPPEFVEGELLFY
WLREKGIHIWDHRPCFLTIAHSDAELEFVVATFKQSIVEMQAEGFLPSPGNGSKALELAG
NGQKQGSGANGSASPQPPVPGAKLGRDPKGNPAWYIPDPERPGKYLQVGESLLQSKAISL
>A0A086M0F7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii RUB|TrEMBL
MANAEKLVKLHGLWFRSLWKWAEKIPHEDAVIWLDENGSKAASLTYQKLRREALIIATCL
RQVHCQPGDRAILCYPPSVSFVPAFLGCQICGLTAVPVYPPGSNDRDSDSIQRIVAMVKT
TRPSVVLSSSPLRYFLKEVFPGAAARCVSDIRWIFTDELPDHVEAGSAFELDSLDIKSET
PAFIQFSSGSTGNPKGCVVTHMALLHNIHLNWRMCGAFHPGTEESLYDLPVESYAEFTEK
YQKHLVATWGHRLRSFSWLPVTHDMG
>A0A099KIK2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Colwellia psychrerythraea|TrEMBL
MAKKQQKSSQTVAKTTNIDNEEQAFNSRLQECPIAVVGMASIFADAKNLEDYWDNIFESV
DAIKDVPSDRWAIDDYYNSDPKAADKTYCKRGGFLPEIDFDPMEFGLPPNILELTDIAQL
LSLVVARDVLNDAGIGDGSGYDRDKVGITLGVGGGQKQISPLTSRLQGPVLEKVLKASGV
DAEDRAMIIEKFKKAYIGWEENSFPGMLGNVISGRIANRFDLGGTNCVVDAACAGSLAAI
KLAISDLLEHRSEVMISGGVCCDNSPFMYMSFSKTPAFTTNEDIRPFDNDSKGMMIGEGI
GMMAFKRLEDAERDGDKIYAVLKGIGTSSDGRFKSIYAPRPDGQAKALKRAYDDAGFDPR
SCGLIEAHGTGTKAGDAAEFSGLVKHFSANNEQKQHIALGSVKSQIGHTKAAAGSAGMIK
AVLALHHKVLPATIHIDQPNTSLAIENSPMYLNNETRPWMAREDGLPRRAGVSSFGFGGT
NYHMVLEEYTPAAQGQYRLNAVPQTILVTAKDEHALITQLQQWQDKLSSVADAQPYIFNA
LVTDCALQTPAENLARCGFVAKNADEAIKMIAGALKQFASNVGSDSWSVPTGIYYRKSAI
KTKGKVVALFSGQGSQYVNMGRELACNFPSVMQAAQDMDTEFSNAGLGQLTPTTYPIPVF
SDDARKAQDEVLRLTQHAQPAIGTLSVGLYKTFTNAGFKADFTAGHSFGELTALWAAGVL
NDSDYMMLARSRGQAMAAPKDATVDTGTMIAVVGAPDKVAADIKDIKDISIANYNSNNQV
VVAGVTSQIAIAIEELKGKGYKVVPLPVSAAFHTPLVGHAQKPFSDAIDNAKFNKPVVPV
YSNGTAKAHSNKAADIKKSLKKHILESVHFNEEIDNIYADGGRVFVEFGPKNVLTKLVEN
ILKDKDDVIAIAVNANPKKSADMQMRQAAVQMSVLGLELNDIDPYSAVKRPLSAPKMSPL
AMKLTGASYVSPKTKKAFDDALNDGWTIKQAHTTPVAVPAPQVVEKIVEKIVEVERIVEV
EKIVYLNSDGTVADGITITSQVTPNTSDVVSSIERSVSQFVDHQQQLLNVHEQYMQGPKD
YAKTFDAVLTSQEAGELPESLDRTLGMYHDFQSETLRVHEQYLNDQTDNMAAMLSTAETN
APAVPVAIKSAEVKAPVVAQPAPIKPNVAQVTQPVPVTPVAAPVVQTQSPAPVQTVATAA
ALAPVAEISVAVSAPAVSIDLEALDLQKIQTVMMEVVAEKTGYPTEMLELEMDMEADLGI
DSIKRVEILGSVQEIISDLPELNPEDLAELRTLGEIVDHMQEKVTSKAQAVSPSVSANES
MPTLHLVDTTVTASAPTIDLKHIQSVMMEVVAEKTGYPTEMLELEMDMEADLGIDSIKRV
EILGSVQEIITDLPELNPEDLAELRTLGEIVSYMQSKVSAAPEAVVANAPATESAPGNVA
GPAIDLAHIQSVMMEVVAEKTGYPTEMLELEMDMEADLGIDSIKRVEILGAVQETIPDLP
ELNPEDLAELRTLGEIVNYMQSKVSAAPVAVVENGPANESAPGNAAGPAIDLAHIQSVMM
TVVAEKTGYPTEMLELEMDMEAD
>A0A449GNE3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia farcinica|TrEMBL
MSSYLLPDGTVPVLISSDTADGVRAEAAAVLAYLDEHPRVSPERVAEMLFRTRVARRYRA
LAMVRTREELLDGLRAVVADTPSRVVVTGDGAASARRIGFVFPGQGSQRPGMGRLYYDVS
DAYRAAVDACAAIHRERFEHDQPLHYLLGDEGRYQDTVWEVQPALMFHMYGLAAMWRAAG
VEPAATVGHSQGELAAGAVSAVMTLRDSVLAVTHRARLVERISPRGYSMAVLGMDREECE
ALLARHSGWAELSVVNAPHILAISGDRDTIVDMVELATARGQFAREIKVSYPAHTSIVAE
LREHFMSFLGDEMSGECFTASEIPCYGATLGAAITPDLTHRDYWYWNLRNRVRFDRAVVA
AVTDGVDTLIEVAEHPVLQLALQENLTLVPREKLPLGRDVKVLGTSLRTAEGLAEFTRNL
ATIAVHDLDYRWDALRTDDGAAPRPPLRDFPHTIMHPRRLWAGPDLPAAEPQPDAAPAPE
RLVETWIPLDKRSMLAPRTLAVVDHTGRCAELADALVAAADRHGATATVLDAAALAGDLP
EFDTAVVLLPELPDTDGAAALDDFAAFFADRAWVPALDRLGPGGQCWLVTTGGESVLADD
PVPHLFHGAVAAGYRSAGIERPGILLRHLDLAAGAGPDQAARIVTAVHTAGECELALRGG
KLYVKRLVVDPATDASAADTDLSHVLIVGGTGQLGLRFCEHFAHAGAGRVTLVSRSGETE
RVAGELNRLRRLGRTEIVVEACDVSDAEAVKRFAATIESAPVSLLIHAAVNYVDAELPDI
TAEMVTEAAGSKVLGLGTVLDIVPFTEQQRILLCSSTAATLSGRGQILYAVTNRMLDILA
RRLRAQGRDAISIEWGLWSVAGPLDEAGFARVADAGVHPMAPGDAITAGLAGPWGDAMIM
SADWAFLREVLDTFGQGSVLPEIATPAAASAPEPDVVEPVVTEQPAAPAAADRPLAERML
TQLHKVMGTDGSESIDGSVPLVALGLDSLQALDFRKRVKAELDRDLPVAAILGGASLDDV
VALMAENTN
>A0A105T2L0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudomonas sp. TAD18|TrEMBL
MPLLPEINRRPIVFLYPGQGSSPQGILQELYQLNADIQNTIDAVLDAVDSVVQERQQQGH
AIAPDMLREVLLTPDTGASLPYGLNQLALYTGAVALSHVLRRSGLQPKAALGESFGEIAA
RECAGNVSITNGARMACALNDAYRPVLNQGSMLLVNASEEKTRATLRKINHPDLALATVN
SPTHTVVSGSHDALQAMIDATQPGTPPPRKLNIAYASHHPQHTGVQQEALRTMPGIPRSP
LTLALYSTVQQRAYTVQDDLIAGFIDNTIKPCHLPNTLNALVRDIANPLFIDLGSNGYMA
RCVSKILPGAQTYAPLTQNAIDLRTHLSGLL
>A0A378RGT4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium aichiense|TrEMBL
MLSDHSGREPLAIVGIGCRLPGGSDSVDSLWNLLCSETDATCVVPESRWNADRYHDPNPA
KVGKIVTRRGGFLSEIDQFDPQFFGISPREAHSLDPQQRLLLHVAWEALEDGGLPADSLA
GSDVGVFIGGFTLDYQLLQNQGLSSRYRFKAHSATGMMMTMLANRLSHAFDLRGPSVTVD
TACSGSLVAVHLAAQSIWNGECTVALAGGVNIMGGPNTAIAESKSGFLSPEGRSKAFSDS
ADGYARGEGGAIVVIKPLRQALGDGDDIYAQILGTAVSQDGHTDGITVPRQEAQEAAIRT
ALARAGVAANDIGYVEAHGTGTPVGDPIEMRALASALTPDRSPTDPLLIGSIKTNIGHLE
AGAGVAGLIKAALVAKHGYIPANLHLIEPTRHVSLTELKIDVPATGRPYPAGKRRLVGVN
SFGFGGTNAHVVLAEPPATAAPAPGSPEPQLPAVLPISARSEEALVAAADRLARHLDADP
DLTLPDLQYTLSLRRSHLNYRHVVIADSKDDARQQLRLLADGGPISGRTAGSAPKLAFVC
TGMGPQWWRMCRGLLDVLPVFTDSIVRTDRELAQYTGWSLVDELRRDETSSRMTETEVAQ
PANFAVQIALAEQLAQYGIRPDAVIGHSAGEVAAHHLAGLLTFEQAVEVVHHRSRLQQRT
SGQGRMLAVGTDADSLMRVMDPQLHDEFGRRISIAAINSPSAVTVAGEADVLAVLAAQLD
ELGIFNRYLTGKVPYHTHFMDAIKDDLLGALDGMSSKDATMPLYSTVTGERLDRYQAGAA
YWWQNTRATVLFEPAIRRMVEDGYTHFVELGPHPALAASIVETAGQQRVSVTAVQRRDQD
DVRTLLNCVGTLHCNGHDVAWGALQHRQGARPVKLPSYPWQTKRFWNETREATESLFYKP
VHPLLGQRVSALHPTWEAELSTVFNPFIADHRVQGSVVVPGAVYVEMGMAVANTVYGRDF
SVDNVVLHRAVILDDTCDPILRTTLNEDDGTLEFASFTATADGEPKWAITATAELNVLPP
APSSLAAADSAEPVVSISGDDFYRRTESIGFDYGDAFRTVRKVTAGEDWAVADIAVPDSI
ADEVPRFRFHPVLIDGALQALFGAPFLGQEENEDPFLPTRIRHWAVYGAPTPEMTVHVRV
VSVTRSHVESDITITDTTGTPLAVITGFVVQSLSESSRMSPDRIDKGVLQIQWQRLEDQP
AGEEAGAVDPTSWLLLSDGTGVGAAIAEEMRRRGHHVRVVGHDDGKELAEGDFAALFDDD
LRGVIDCWPLDITADCSVEDQHQLGVLTALRLAKALAQQDTPDQLRLHLVTANAQPAPGT
ELRGVGQAAVWGLGRVIGHQELPEHWGGLIDIDAADDHVQTAARVCEHVLDGGPEDQIAI
RGEVTYVPRLRPCDQLTRPFPTKLSTDATYIVTGGAGALGRVVATYLAERGARHIALWGR
SAIPPRDSWAGLTEEHAHYETVKTILDIERRGVHITTASIDVADSHQVAAWLRDHTGGGG
QPVRGIVHAAGSVNDQLLVNISEDDFTAVMAAKVTGALVLHDALKDHELEFFVMFGSAGS
TIASPGQGNYAAANAFLDAFAHYRRQQGLPALTIGWGPWSVGMVEELNLEKLYAARGIEL
ITPAVGALILDRLINQQPADVVAISADWGRARQAGLGSRLPMMFAELGTSETGPGAGESD
GSILMELATTPEADRPAVIADQLRQIVAAVFDCAIEDFEPDDMLEDIGLDSMMAMEFRVR
INMTFSIDLPVLEILRGVSVNSLADRVLAELHFIHGEVATPTTESAGPTEAADLDDELDQ
LMAELSDAELQELLAQLENEPGSDAGEGIS
>A0A3S4X3W8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Serratia rubidaea|TrEMBL
MKQRVIASGWGQCSPLAADVPTLIEAIAAGRCATSAPWFDNDDDWQNLRLGNNPHTARAA
RADAAPWQQLQPVIDEALTMAGLPASALQGPRVRVFLAGNGMRPNIADFAGYQDRNDAED
LLFFPAIKQLHADSYAQDALARRFVETYRLDWPPTSVYSASNSSLTALHLAQAGIAAGQT
DVALVAGWLKIVLQDVVFMGGQDMLGNGQSQPFNNQDNSVLLADGAVALVIESEEHARRR
GVTPAIAISSSVCRQSSGGRGGAFTADFRTIAQTIDGALQAAGLTPQDIACALPHANGTV
AGDKAEAMALQKVWGRNGIPVVSYKGQAGYVATCSGVLDFMLAADALLQRRLLAATGRHP
VDAALAIHVHMDAPPLSLRTPHLLKSGIGLDGSVIAMVLSDCREGIDE
>A0A0U4CDX2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Aeromicrobium erythreum|TrEMBL
MDRHAADHHAPNDVGEHAAALPLGGADRDAVRALAQALRQEVVAGRVHDVRALGSALAAD
AATSRTDGHRSVVVLDDAASASDLVEVLDAVVAGRPHARLVEGAPRRDPGMTAFVFPGQG
AQWPGMGARLREESSIFDEAMTRCLAVLGEELPGWSEDALHSEAALRAVEVVQPALYAVQ
TSLAALWQAHGVRADVVVGHSIGELAAARVAGAFSHDDGARGASRWSRAMMPLVGVGDMA
SVGLSLDEVLALLERWQDPDVELAGVNGPGSVLLAGAPDAVRRRVAELQAEGVRAQVIAV
EMAAHSRQVDAVAADLAGAFDGLAPASLALPFVSSVAAGHVDGPDLVGAHWARCFREPVR
YDQAVAVALADGVRTFVEVSPHPVLTAVTRQTIEGEGVEAQVVSTLRRDVGGWATFLQSL
AQVWVAGTDVDWSAAYLGVEPAGLPVAVPVGPLSPAGAGPAGQEAAPSVAEFVAAVRAHA
ATVSGREVRADETFLDMGLDSVLVAQLRTQLQEELGRAVPITSFYDFPTPQALAEALTGG
SDRRPARPAPPVARVDDEPIAIVSMACRLPGDVDTPERFWSILSEGRDLVDGLPADRDWD
VDALLHQDTSRSGTTVQRAGGFLRAVADFDPAFFGLSPREALAMDPQQRVLLELSWEALE
RAGIAPYSLRRTRTGVFVGLIPQEYGPRLAEGGAGVEGYLMTGTTSSVASGRIAYTLGLE
GPALTVDTACSSSLAALHLACASLRRGETPLALVGGATIMPTPGMLVDFSRMGSLAADGR
SKAFSADADGFGMAEGAGMVVLERLSDARRHGHPVLAVVRGSAMNSDGASNGLSAPNGRA
QVRVVHDALVDAGLSAADVDLVEAHGTGTRLGDPIEASALRDAYGEDRERPLLLGSVKSN
VGHTQAAAGVVGLMKLVLALRHELVPPTLHAAEPSTEIDWSDGTLELVQEPTPWHRGERP
RRAGVSSFGISGTNVHAVLEEAPDTAAAPAPPTTPVVPWVLSGASESAVATQAARLADHL
EARPDLDPLDVAHALATGRSPLGHRVGLVPSRDDAVAELRRVADGTSQAARGVVEAPLRP
VFVFPGQGWQWAGMAVELLDSSPVFARTMRECARALRPHLDLDVVAFLREEAARATPGGA
LSTERVDHVQPVMFAVMVSLAATWRAQGVEPSAVVGHSQGEIAAACVAGLLTLEDAARIV
ARRSVAIAGMTRRGAMVSVAAPVEQVRERIGDGLDVASVNSPTSVVVAGDADALERLVAE
CAADGVRATRLPVDYASHSRHVDDVERAVLEGLSPAPRPLPGAVPMLSTVTGRWVGPGEL
GPQYWFDNLRSTVRFSDAVETLVESGRTAFVEVSAHPILLAPVEQTAEAVGVDVVTVGTL
RRASGGPDELAASLARAFVGGVPVDWQETFRGSGATPVELPTYPFERRRIWWSPPDRRVS
VGGEPDPRAYRISWRPVAADPGARLTGTWWVLHRPDHDAGLLAGVEQELSRRGAQVERLC
VAPGGAAHDVATRLDQGLDVAGVLSLLAVDAPEDTSAPLDSDAVRDLLGVVQSVVAAGAT
TRVWCVTSGAVATGPHEAVRTLGGGALWGLGRVVGLENPAVWGGLVDLPADVGDDVVSQL
GAVLATDDGEDQVALRGTGPWARRWVRVAAPATQQWRPQGTVLVTGATGGVGRHVARWLA
GRGARRLVLLSRRGPQAPDAAALVRDLEEAGAEVDLRACDVTDRDALAAVLSYIGDDMPL
TSVFHAAATLDDAVVTELTAERIERSSRAKVQGALHLDALTRAGDLDDFVLFSSFASAFG
APGLGGYAPGNAVLDAIAHERRRAGLPATSVSWGTWAGGGMAEGPVAERFRRHGVLLMDP
DAATASLVSALDRADPAPIVMDVQWRRFLAAYTALRPTRLFDELSDAAEPPAHPVRGSEP
AGPGRPQDVGALAALVRDRVATVLGHESSDAVDVDQPFSRLGVDSLSALELRNVLGTALG
LRLPTTIVFDHPTTRRLTAHLAEETGLSEQAVEAGRRPVDDRDDDRDDDPIVIVGMGCRL
PGGVDGPQALWDLVAAGATTATDAPDDRSWSVGELARGGVARGSFIDGAGDFDAAFFGIS
PREALAMDPQQRHALQSVWETLEHAGIAPDSLRGSRTGVFVGHSNQGYGTGAVEQDVDLE
GYRLTGSTASVVSGRVAYVLGLEGPAITVDTACSSSLVALHLAVGALRSGECELAVAGGV
SVMAGPEVFVEFSRQGALAADGRCKPFSSAADGFGLGEGAAFVAVQRLSVARREGRRVWG
VVAGSAVNQDGASNGLAAPSGVAQQRVIREAWARAGVGAGDVGVVEAHGTGTRLGDPVEA
SAVLATYGRGRGGAGPVLLGSVKSNVGHAQAAAGVAGLIKVVMGLSRGVVGPSVVVGSRS
ELVDWSAGEVELAEGLRAWPVGPDGVRRAGVSAFGISGTNAHVVVEQAPASEPVPAPAPG
GLGGDLVPLVLSARTPQALARLAKATVDRLAGDDAPDLADAAWTLATGRARLPHRAVVTA
DRASAVTRLGAVAEGLPSVHVATTDPSRPAAGVTGPVMVFPGQGAQWVGMASGLLGVEVF
ASALAEVDVALGEVLGFSVREVLEGREGAPSLDRVEVVQPALFAVMVSLARWWESVGVRP
AAVVGHSQGEIAAAVVAGVLSVADGARVVARRALALRALSGGGAMASVALPVERVRAWVE
QVGGLEVAAVNAPAQVVVAGDVAAVEALVEQGRREGVRVRRLAVDYASHSVHVERVREAL
VGELGVVQGRAGRVPVFSSLRGARVEGPELDGAYWYENLRGTVRFDAAVRAAMDEGHEVF
LEVSPHPVLAAAVQETAAETGVDVAVLDTLERDVEEVGRLVRAAGAAFAAGLDVDWRALL
APAQVVPLATYPFEQRRYWLTPRRAQVQDPLAGWFLTETWTSVTPRPEQQVPEQRTPQQP
VPGRWWVVVPDDGPPPPWAGPLGDALRADGADARVVAPAELGHELRPGDGVLSLLAVDSG
DASATLALLARLQDHRGPVWVATTSAVVVSDDDAARVRPDQASVRALAQVAGLERGAAWT
GLVDLPAASASEAPPALDVDAVVSALRGAEDQVAVRDGRVRARRLVPHEVAASGPYVPPT
GTVVVTGGTSGLGAVTARWLIGRGARSLALLSRRGPGTPGVEQLVAELRDAGAEVTVQAC
DVTDRASLRAALSVHDDVTGVVHAAGLPQHQALADMDEASLRRVLDVKATGAALLDELVP
DAGLFLLFSSGAAVWGSNGQAAYAAGNAALDALARRRHAAGRAATSVAWGLWETGGMTQD
QAAVDYLRDRGVTPMASEAALSALERVLAVGVPNAVVAHIDWPTFAAAYCAARPRPLLDL
LRGGTPTEGAQHEPEPAEETGAEAAPGLGDELAGLPAVERRARLLRLVRVHAAAVLGHDD
PATIRPRDSFKDLGFDSLAALRLRDGLQKASGLTLSSTLVYDHADATEVAAYLDTRLDVD
VPAAPSGTQGDGLDRLEQELVALDDAGRAAAVDRLLAVVARLRTTPAEPGPDEVADLAPD
EVEDDVEVDDDLLDADLDELVAALGRELGDDGGT
>A0A1V2RR90|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MFTGQVSFKDQPWLSDHLVHGTAVLPGVAFVDLLLHAGGHVGCRQLEELTHHAFLAVPEQ
GARQLRITVGAADEAGRRPFSVYSSPTSEAGEETAEWTRHASGFLTDAAPETEPYDLTAW
PPVGGEPVDVEEFYRGFVERGYEYGPLFRGFRAGWRVGDAIYAEIALPDGTDPEAYGVHP
ALLDSALHPLMLWYGSGPVRLPFSWSGAALHAVGPSRLRVRLTRSDRDVLSLSVADPTGA
PVVTITGLAMREVAPEHLTAARARQSDDLYELSWVSVPAPEPQDTGRWAGLGVPDVTAAL
REAGVDAVDHPAHATPGETSAAGAAAPRVVMAGPVLSDDGDLVADAHTAATELLTLVQNF
LADGALTEARLLVLTRGAVAAEDGEQVPDPAAATAWGLIRTAESEHPGRFVLIDVDGSDA
SYRALPAALATGEPQLAVRAGELRVPRLVRAALHAPEESGSGHADGTNAGLDPDGTVLIT
GGTGTLGGLVARRLVERHGTRHLLLASRRGADADGAIELAADLKELGADVTIAVCDTTDA
ESVSGLLKSIPDEHPLTGVFHTAGVLDDTTVSSLTPERLSAVLRPKVDAASHLHTLTQER
DLAAFVLFSSVAGIVGNAGQANYAAANTFLDALACHRRAQGLPALSLAWGLWQQTSGITA
ALDPVGRARLGRGGIAALPTAQALDLLDLALGSGQSEQPAQGVLVPARLDLARLGDGGAP
VPAVLHRLVRPRSRTRQAAQSGGASPDSLRQRLASGDEAKQLEILLSYLRGQVAAILGHG
SPDAIDADRGFLEMGLDSLTSVEFRNSLNEATGLRLPPTTLFDYPTPTQLASMLRSSLAP
EPAPAGLPQALAAELDRLESNLATVGPDVRATLTTRIQGLLSKLNSAEGVEGVEGEQGQG
SAVKIDAATDDEIFDFIDNELGLS
>A0A433DWF1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. NP10|TrEMBL
MTLLDVLLDAVREAPGQIVVHVRGDGSELTVTLRELLEDSLRVAGGFREAGVAPGTCVPL
LADRSEDFQPMFWGSVAAGLVPVPLAADTRRVLPVWEQLGRPPLVVDASTAPLADELPDG
ARALTLDALRAGPLLREPAPGGRDDVAFLQFSSGSTGAPKGVEVTHRAVLANLEQIRAAS
ALSADDVVVSWMPYFHDMGLIGTHLAPLAARARQVKIGPLSFAKRPRLWFEVAARHRATV
LSAANFALALAERRVPDDVLARLDLSAVRLLLVGAEPIAPAVWRAFAAKTRPAGLDPAAA
QPVYGLAEATLAVTFPPPGEVAEPLVLDRASLSDGVAVDTEPGYDAVELMDVGQPVAGCA
VRIVDDRGDVLGDRRVGHIMVRGPQLARGYHGLPGVSAETFTDGWLRTGDLGFLRDGRLC
VTGRHKDVLFLNGRTFHATDLEEVAAAIPGVPPGAPAVVGSTDPVTGAERVVVFVPWARP
PREATEVLEHVAARVREALLHDDVRVLALPPGAFPRTTSGKLQRRRLRERFEAGGFEAGG
FEARVFRADSFGTGSFATVRPAAEPRADAPRADVPQVDVPRSRAQTVEAVRKVWARVLDR
TAESIGVHEPFGRLGGTSLKAMEVLVALEDAFGVTLPPAVIRDHGTVAALAGHLLTVVPG
PAVSAPEAARTGEEGEAVAAVIGMACRFPGADTPEDFWDLLIDGHDAITPVPHGRWDDDT
RDRQAAPPKRWAGLLKDPDAFDADYFGIGEDEARAIDPQARLFLELAHEALERAGYAGPR
RRGRRVGVFAAVGDSGYREVLDRASADGSPLPTTLTGNLPALTAARVSQSLDLDGPALAV
DTACSSGLVALHLARRSLLDGECDLAVVGGVNLHLTATPHRLLEAAQALSPTGRSRAFSA
DADGFVPGEGGAAIVLTRLDAARLADDEVLAVVRGTAVNNDGRSMSLMAPNPLRQREVIT
RAYEAAGVDPASVTYVEAHGTGTAVGDPIEVRSLAHAFPVRPDGEPRLLGSVKTNIGHLL
NAAALPALVKVVLALGHRRLPPSLHHTPPAPGVAPAGFSVVAEARDWTSAGPLVAGINAF
GFGGTNAHAVLEQAPTPPSSAGAASSSSSAGAVREVAVEGPHLLTLSAQSAGALRDAVDR
LATHLESRPGLREGDVCRTASTAWDEGPHRLAVIADGDLRDRLATIAAETGGAGGRAGTG
GAGGRAGTGATGLPGASVVRSRPRVVFLFPGQGAQSPGQDRALYRTASVFRDTFDEASAL
LGPVCGRSLLDWGLDPEVDPAAQAMTEVAQPLLVASGVALARQLRTWGVEPAAVAGHSVG
EIAAACVSGVLTLREAVRFAAERGRLMGAFTEPGAMLAVRGGEDAVAAAVAQSGGDLTVA
AYNGPGLQVLSGTVSAVERAALALDAQGVPTRRLRVSRAFHSPLMRPVSDQLADAARALT
PQAPSVPLMSTVTGAWQPVLDPEYLRDHAERPVLFGAAVERLAREGYDTFVEVGHGATLS
GPVRAATEAYAPGESGGGVTVMSALTGRSAGRTEPARLPDDRCGGRGDLLGTVGRLWSLG
MPLDRTALDAGHHRVPLPTYPFQRRRYWADPPARPLLHEVLWEDDALPGKAARSEESARS
VRSVLLTGPDPASVDRLASQLAAAGVRRYEAGDAGRPDAVVLVAGPAPVQDTGDALGRVH
DAATAAFGEALARFDESHASRLLVVTEDVHATGTGRERPRPAHAVLGGLLMALPQETPRA
AATALDLCSLDTPSQRLTAVLAELGSSGTPGSTTIVAWRAGRRLTRRFVRSAADASAPAE
STRSALPPDGTFLITGGGGGIGAALARDLAGRGRPTLVLTGRSPGLPVGLADELRTLGAT
VHYRVADVSVERDVDALVAELPRLDALFHAAGVVRPGTLRNRRPEETADALAAKARGTLL
LSLALRRHGLDPAVRVAFSSVSAVLPGLAGALGDYAGANAFLDAFAASERHAGRPWQSVN
LAALAGTGMAATLGTGTGEGSTTVRNSGGRPVALAPALAALRMACGVDAAQLLLADLTPP
SAPVAPNSPEARATTTEATESGSAASGRTPTEDSGTGTNTAALLRRLLASALRLPATEVP
DDEPFLALGLDSLAAVDLVRQLERELGTTLPATLFFEYRTVAELAAHLDSTPASVVSPAL
ARTPDPVPDGSPFPLTPVQLALHTSSRFHPDVPAHGFVRQTVRGPLDTRLLGRALSALAD
RHTMLRIRIENTAGTNSTEDGIGSAAPAQHVAPPSALSTWYEVRELPGRIEELETALCNR
PFDLSAESPLRAVLARESPELSHLVLVIHHAAGDGYSLNVLAGELWSLYTAFAHGDAPTL
PALGTDFARYAAAAAEQRSSADGARDLAADRRYWTGRLASRGEPLRLPYDGDPRALPSAP
LTTHQSSLDPALTAALEKRAADQGVSLFHLLLAVHVRCLARWSGQRKIAVNVARARRDDR
LAGLDRLVGPLADTLPLLTSTDPDEPVGALAERLAAIWLESEQHAGLTGLDLARLLPTDP
AGSGPRTVSPAGFSFSRFPAALDERCPVSVRPTAAGTATAATRLSLLCWQDETVLRFSWN
FPVRLFAPETVARLDREFHDELAATAAAAAPLPASGSATLVRRLVERFRATPDAVAVDTG
AATLTYGDLDRASEALAASLRARGVTPGSLVGLLTEPGADTVVAVVAALRAGAGWVPLDA
GHPTARLVDQLTRSGARAVLCHAPTRAVGEALGDVTLVPVDVPPSPLSRDFVRYGEGAPA
PGTLVDADADGIAYVIFTSGSTGRPKAVPITHRSMENYLDWAIDTFGYDEHDRLAQTASP
CFDASVRQLLAPLLVGATVVTVGWDLLRDPDRLLTHVERRRITVWSSVPTLWEQLLSASE
ARVRTGAPLPDLSALRWVHVGGEALSPAHVRRWFDLFGDGQRIANLYGPTEATINTSCHI
ISDRPDDQVRRLPIGRPVSGTEVEVVGPDGEALRSGEAGELLIAGIGLTPGYLGEPALTE
AAFTVRRGRRWYRSGDRVRCSKDGTLEFLGRLDDQVKIRGNRVEPGEIEAVLQTHPDVTH
AVVLAEDGRLSAFVTPGPGSSGASGSSGVDAVALRRHLAESLPAYMIPSRITRVDTMPLT
GTGKIDRRALPALGVAPPPSPSRTAATRTAPRTPTEIRLAAIWSALLQADDVCREDDFFV
LGGDSLFVLEVFARLEKQGGPLPRPTVIYRNRTLAALASAVDAAAAEASDNAVDTAAGAA
SDAGAPTPFPLTPTQRGFLLAEAIAPGTTSSWLSRFRLYGRLDTARFQSAVDTLVGRHPM
LRTVFPAGARPAVQQELPSSLRLPVDFETLTDPDRVEERVAAERARRFEPWAWPLLRLRV
LTVAPHEHVLVAHAHHIIGDGYSAALLVRELIPVYDTLSRGDVPAQAPLRSTFRDHAVRL
AERSAAPAAPAAAPSHDGRWARLSAPYRPPVLSAGTDTSVRSDNATNPLFHTYGFTVDAD
QVEALRGLAARGGTTLYAPVLTAYYRALAATTGRADLVLGLAVSGRDHALPDVHRVFGPF
ATAVPLRPAGPASGRRDGAGFEDDLRRLAAEAAEARTYEGAVPALPNGLPLASQFFFTYL
DFSALGPESGAGLTVSREDGDSVYTPPPAGTDVFLSAGPEGGRLRVTVRAVATAFTPEAL
AAFADAVRDGLAHAAASTVPRTGPGRLDGAGRPSRLGEPDLTGRDEPVDAALVGYLPSPA
DLARLAGLPEAALPREELRSLLFPDGRPRLLETLRTPLGRSGFVCVPLFADELAPGDALL
GHTTRGVELASALGARAVSLAGMIPSLTGYGFDVLRAVGTTDSVPAVTTGHAATVVSVVR
TVHAALDATEQELGSLTVAFVGLGSIGSSSLELLLTLAEEPPARLLLCDVPGSGPRLKEL
ADSLLERGLAEVVEVVESDQGLPDAVYGARLIVAAVSGGGTLLDIDALAPGTTVVDDSFP
HCFDTSRAFGRMERAKDVLVVGGGLLSAGAAERQVAEGLPAAAVAGYLAQPMVADAIASC
RLESLLHASGAAVPLVHGPVGAATGLAYWEAAEAAGIRAAPLHLLTRTIGPGMIEGVVSG
RD
>A0A433DRB8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. NP10|TrEMBL
MTQEIPAPHEGQEPIAIVSMGCRYPGGVRSPEDLWRLVASGGDAISPFPGNRGWDLADAD
GRSSTRHGGFVHDADLFDAKFFGISPREAAGMDPQQRLLLEVAWETFERAGLDKDVLAGS
DTGVFVGAMAQEYGPRLHEDNEDAGGYRITGSTTSVASGRIAYWFGLRGPALTVDTACSS
SLVALHLAVQALLRGECDRALAGGVAVMPTPGMFIDFSRQGGLSPDGRCRSYSDDANGTA
WSEGAGLLLLERQSDALAHGHEILALIRGSATNQDGASNGLTAPSKSAQEKVISLALDRA
GLHPHTIDLVEGHGTGTELGDPIEARALAAAYGSGRTAEHPLWLGSLKSNLGHAQAAAGV
GGVIKVVQAMRASVMPATLHTGTPSRHVDWGSSGLALLHEARDWNRAEDGPRRAGVSSFG
ISGTNAHVVLEEAVRAPAPEPTEDDAPAGGPHVWQLSAPSPDALRTQAAALGAFLTDAPD
TAPEDVSRVLRSRTRFAHRGAVVADDAADLARGLGQLASGTHAPTSPGRYRSPTVLSGEA
RQGSAGPVFVFPGQGSQWRGMGRELMDRSEPFRRSVEACERALDPYVDWRLSDVLRGEDL
DRVDVVQPALFAVMVSLARMWEAAGVRPAAVVGHSQGEIAAAHVAGVLTLDDACRIVALR
SKALHSVAGSGGMVSVPLGAEATQGLLDAADGTNGKAGIAALNGPSSTVVAGGVQALEDL
LAVCEAHGIDARRIEVDYASHTEAMDVLREPLAEGLAGIAPGPGTVPVYSTLTGEPIEAS
AMDASYWFENLRNPVRFQAAVQRLVDRRHRVFVEVSPHPVLTFGLQAILEAAGVRGSVLD
TVRRGSGGPGQFLTSAAAAQAVGVPVDLGPLQPPGRRVELPTYAFDRSRYWTSAPAVVPA
SEAGPDTGDFTLRSLELPTGATVFAARLDPARHPWLADHRVRGTALVPATAFLALLAEAG
RSAGLPVVQELTLGVPLTSPEDTAADLRVLLEPADAAGHRRLTVHARPADAEAWTAHASG
VLAPGSPQADTAAPAAWPPADASRIDLSDAYQRLAARGYGYGPAFAGLRGMWVRGTDIFA
EVTLPDGTAEGSGATAHPALLDAALHAAVLQSGGELVVPFAWRDVTLAPSTTRDLRVRIS
TEGDEVTVHCADPLGRTVATVASLTMRPLAQEAAPGDLDEEGAGFALHWAPVPETPEALA
PDAWAALSTPGLGAAHDFPGLDGVARPAPAVLVTALGGDGSEDTLPADVDALAGETTDLL
QSWLADPGFSSARLAVLTRGAQSVVDREPVRRLASSVITGLVRSAQAEHPDAFQLIDIDD
DPASLRALPHALATGEPELAVRAGALLRPRLRRPSGGTLREPDGHRAWRLDVTSKGTLDH
LALLPHPEAEAPLGPREVRIEVRAAGLNFRDIAVGLGLVASEKTMGSEGSGVVVETGADV
TRFAAGDQVFGVFERSLGPLAVADERMVKPLPAGWSHAQAASVPIVFITAYQCLVEVADV
RPGESVLIHTATGGVGLAAIQLVRHLGGEVFATASAGKQDTLRAWGVPEDHIASSRTLGF
ADAFRAVTGGRGVDVVLNSLAKEAIDASLGLLAPGGRFAEMGKTDIRDIGRTEADHPGIT
YRAYNILGISPGRIGEVLDELIALFESGALAHLPLRTWDVHEGRTPLRMLSRAKQRGKLV
LTMPRAVDPGRPALVTGGTDGLGAQVARHLVAAHGVRRLLLLSRRGPDTPGATELRAELA
ASGAEATVVACDVTDRAALAKVIAENPPGSVFHTAGVLADAPLTQLTPARLRAVTAPKAH
GAWHLHDLTRDLDLSAFVLFSSASGVIGSPGQANYTAANTFLDALAQHRRAQGLEATSVA
WGLWAEQTGMTAHLSERAVGALAGIGIAPLATDRALRLLDEALASAGSLRVPLRPALTGI
RPGSRAARLFDELTGPDDAPAPTGSRDLPAEGPQETGQARQTGALPAEQPSDEAFLTLVR
SHAADVLGYGDASAVGTDEGFRDLGFDSLLSVDLRNRLNAATGLRLPADVVLKNPTPRAL
VESMIKALGEA
>A0A4U8W7P2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia cyriacigeorgica|TrEMBL
MARPFSGDADPVVIAGAAIEAPGDIDDLDHFWAALAESRELLGPFPRDRGWPLREVFALD
RTEGWGKVPDAGGFLQGAAEFDPQFFGITPREAIAMDPQQRVALRVAWRAIEHAGINPDE
LAGAEVGVFIGGSVTEYGPRAAEVNEFSGHRVVGTALGALSGRISHVLGLMGPSVTVDTA
CASSLTALHQAATAIRAGECEWALAGGVCVMGSPGAFYEFAKNNALAEDGHLRAYSAAAT
GTVWGEGAGVVVLERESRARAEGHRVYARLLATRVNHNGGGAAIAVPSANAQEKVVRRTI
EAAGIDPGLIGLIEGHGTGTPVGDPLELAALRDTYGTDPSHGPRLGSVKTNLGHAQAAAG
ALGLIKVLLCGANGQIAPSLHAADPTPAIDWDSTGLRLATTLEPWQATDGYRYAAVSSFG
VAGTNAHTILAMPQLDDYPQRGDMPEVSHA
>E6UAS3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminococcus albus (strain ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7)|TrEMBL
MNQQVVRDMDIAVIGMAGRFPHAANIEEYWKNISEGKDCIDRTGVKKENFVDAYGQLDDM
YFFDAEFFGVNHSDAVCMDPQFRIVMECVYHGLEDAGYAQDTGDREIGLFLGADENYYVW
NHYYSKKYSGQTFDRVSMFLQNTLASSISYKLDLQGPSMVMRAACATSLATVHYGIQSLL
NYECNLVVAGGVNIREYDEGYQIVDGVSSSSGALRAYDENGDGYVPGNGMGVLVMKRAED
AIRDGDHIYALLKSSALVNDGSRKAGYHASSVQGEAEAMVKALELSGVSPEDIQYIEGHG
TATPLGDRVEIQAIDRAYGSFTGNYQVEIGSVKSNIGHLNVAAGIAGLIKTILCVEKGMI
PPTINFAKENPELLKYQGKISVSTSLHPWKKNGVRRAAVSSFGFGGSDAHVIVEQAPEVH
KSAPQAMDHFLVPVSGITEAALERNIELLKAFIAKHHDMTAEIAYTYQVGKRHCRCRSYL
ILDAHGEIVTESVNDMFLRLKSLGERYVGGEDIDWNAEWEQKPSRIPTTGYAFERTEYKH
PETEFVSAQRTSVKKRVLIQDGLSDSRYALSSYIAKRPEVKLYLAEREDRNRSFVIGDPS
EVWQKTSQNAERLCEASQIHLIGADSSAKQDMEQLCRLGAAYFLSVCRFSGSHLTMHQWM
ADNEFLTENVHFLRFIIGLIRDASILITKDDRLTLLNAEKMKEMGGAFDAAVITFCKDHP
EFADIAELLAESVHHYMEFAQGKRNGNDILRQGGSINSLQNVGQTATTETVYCKLLAQIL
KQGKQSGSELSVMEIGGGTGQLTGEIVKQLGSEQLRYLFTDVGKGFVQNQRLSAKQNQWD
FMEFSVVDAMEDLTMQGIAKDSLDVMVEDNMLHLLKDLPAGLKNIRQVLKPGGYLAAVQV
ILTYDVQECVFGILPGWWNYKDSVPARERPYLSIEEWKRCFREAGFELVLSFPETDAPEL
TNTAIFLLRKPENAEGTLDVVREERLASLQKNAGSAQVMFYRNEDELAQICNSLFDAEQL
LCEDTCKITAVDTVQKKSAETTLLDELKTIATEILNIDDIAVDEDIMDYEFDSLSVLILN
ANIKEKYHTDIGIASLYELGSLRNISEYLENRMSQESEGGMDHGDQSAAEEEKYSPEDLL
DELFE
>A0A654U6R3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MGSVKSNIGHAQAAAGGLGLVKVILAAQHAAIPPTLHVDEPSREIDWEKQGLRLADKLTP
WRAVDGWRTAAVSAFGMSGTNSHVIVSMPDTVSAPERGPECGEV
>S8GDX1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii (strain ATCC 50611 / Me49)|TrEMBL
MTEAATPQNVTSPADLSKQNVSFRPGVNAVEFVSGYSHAGSVVCSLPSPIFFNKASSSNG
NCESNASTASSSAALGTEASSNVRTGTVLIFDCGSGNTWQHLRQWLSDEGASHIVVVHAC
AEEGADTLGVKTLHPSRVNGGQGCSQTLIKEVKCRPHHPEEVVELFKLLKEGLHFPLVRG
IFYILGEKLDSLLANQTTSSVHDMMKTASGAWSIHHALGQLGMEADLDFFIFFSSISALF
GSISQSISAAVHASLDALAYYRRHLGLAATSIQWAPWADGSSATSPQIVRHWLEKGGVSS
VRNPLAAVSAILKNHTAIGAVVACFHADPTIMHEMGETDQECTFLSSGPAANTRDSTSGN
VKVRTNPVKSRVFQNVSPSTDTCGENHKDELLVILTQLVRREVIEIASCYVFFEGNNLST
DESLVDLGLDSLSAVELRHTLQQRFCVNIEPTFLQANATIDSISALLVTHVATSLTGALP
VLPLSCPGLASAVDDCALVSLALRLPGRCDSLDAFWASLQSDSGYCRPGASEACDQCFMH
RAGSGELPAESQSIGTNLDARKGFCWLSNRDAFDSHFFGISFTEALATDPCHRLLLEATY
EALCKLNTEQQSGTSGTPIAVFATSSSTQMRASLPSYTKPASSQNTQDNNGCLAASFLSY
HLNLTGLAVPIDGSDSASLIALDLGREHLRGTDSVCQAVVVAAGSLLPICSHGWPSACTS
PTIRRFRGRDDYAFPDRETYAVPRGEGIVSVVLQRLSVARENGNSPMAILKGISLIRMGR
GERPIPSQWRTADVKLRRKTIVEALKMSRVEPRTVAVLETDGLTGSQAEDAYTVEAMADI
FGPRHLAESCSPLVIGNASLHIGQAREASGLATLAKLVLMLERGYAPPIPRLRRLHPDVK
RGILPSGFVMFPCKKMDLLAFRQHPDHVYGPNEKRDQKEGRPLIGCVSSLGSDKTSGCFI
VESSPRRHGRTSDTRVSLERAVPLAGTKDACSHNYLHVRSTDGSESEIRGDDRAVWLFCD
DLWGLQSVGRGLYCSDPAFAALLEQAERVLGNRIPQPLSCLLYPSTTAEFQKAEDALAFP
RIAAFVLFSLQWALATCLRHQEGEPTAVMGLGVGEIAAAAVAGILSLEDAVELLELLSSE
TRTCDNRNKPMPGGNVNSGGLFDRGNSGTGGCGVAQDCKSPWVLCGLNKTPTSESAALEF
SVLESRRGSSSRKSSETPTSNTTPHNRDVFQERFSRKPRRATCPSPIIRHAWEKVAHGNP
ENDEEAELECPSSQSRRANCPSPAIQHACEETAHGNHANDGEADLLMDLFRFRPEPSEPL
GQVTARIALRNATCLFISTVSGRLATDTLIRAAEYWDPLVPKTQRVHRAVETAVQVAKTA
KLVCIGCSAQDGVHLSVGLPSVHPISPSPLRIFCFTGSSPSPQLLAPCESASGSSPRVAV
VEHHGADSNLGGGAPWWKHLLFRLPQLEGFPSGCSASTRLLADRLVADVPTPDNHMINNP
QTAAVQGAGETLGTLREGSSGEGEDGEKGYRSESVNTQHPVYKVYRRCSEPELHESELSL
LCSDTVCQPSLEKTVELFIGTGLEQQGKLSTVSSSWLVFSDIVAPSPISLYSTLAFQNED
GEQRFCTLNVASQVATVYAEKVKTQVCSIIIECKRGFKPPREIARCYFVKNQTAVGKHEP
AVSSLSRIRWLPATKLPEGWLRTRRPHVWPCKIKVTKAACPLPTRRVDLQEIYWGKRHIL
CRFRMPRNPPRDGVEKSTQLIAILARLVTVSVGVAATCVLHETETSGRYSHSHPGPQVED
DQKTHMDALWVCPYVPFSECWCVIRHRRNGSSIKEGKGRDWETCDVEIFSENGTAVAVVL
GFGIQSHALSMRMMGGRGNDGDSSVSTTVCVA
>A0A2K8RJF9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MAGMPEPTDEKVLTYLRRLTADLRRTKERLRAAEAREHEPVAVIGMACRLPGGIATPEDL
WSVLAEGRDAITPFPTDRDWDLAALHDPDPEKPGTCYALGGGFLNDATRFDADFFGIPPR
EATAMDPQQRLLLETSWEVLERAGLDAHTLKGSRTGVFVGLMHHEYAGLVRGIPREVEGY
LGNGSAGGIASGRIAYTLGLRGPAVTVDTACSSSLVALHLAAQSLRQGECSLALAGGASV
MASPLSLVEFSRMRGLSPDGRCRAFAEGADGTGFAEGVGLLLLERLSDARRNGHEVLAVV
RGSAVNQDGASSGLTAPNGAAQERVIRDALAAAGLSGPDIDVVEGHGTGTRLGDPIEAGA
LLATYGQGRERPVWLGSLKSNIGHTQAAAGVAGVMKMVLAMRHGVLPRTLHAEVPTTRVD
WTSGAVRLLTEEVPWEGDRRAAVSSFGVSGTNAHVILEAPPAEPPAEAPPSGQRLLWPLS
AQSPEALREQARRLADAASGLDPADLSHSLVAGRAALRHRAAVVGTTTDDLRRGLAALLA
GEPAGHLALGEAADSPSAVFVFPGQGAQWVGMAVELLESSAVFAARFAECERALSPFVDW
SLVDVVRAGDFGRVDVVQPVLWAVMVSLAALWESVGVRPDGVVGHSQGEIAAAVVAGALS
LEDGARVVALRSKAIAGLVGGGGMVSVPLPVGEVRGLLPEGVSVAAVNGPSSVVISGDVA
GLEEMVGRVAGARRIPVDYASHSVRVEEIREDVLRACEGISPRRATVPFFSTVDGEWVTG
DELDAGYWYRNLRQTVEFEAGVRALLADGMRHFVEVSPHPVLSVAIEDHPDALALGTLRR
DQGGSDRFLRSAAEAYVRGLPVRPVVLGGRRVALPTYPFQGRRFWLRDTGGRTDVAGAGL
EPSGHPLLGAVVELDDDGWALTGRLSLERDAWLGDHAVLGSVLLPGTALLELAVSAGRRA
GFGQVAELTLRTPLVIPASGGVAARVQVGPEAGGRRAVTVSSRPDGQPDWMCNAQGVLVV
EELSDGAALPAWPPPGAEPVDLTGFYEGRSAAGIDYGPAFQCLRALWHKGDEVFAEVEHE
APGEGFALHPALLDGVLQATASLGRDEGVRLPFSFSGARFGPYAGSRLRAHVVPAADGAV
SVLVADDSGTPVASIDAVTARPVTGALLKPASTSLLRPATTALPSGPVPSRRWAVLGEND
RELAAAVDARWTVPDVRTAVEAAPDAVAVRIPRGDGDPVGGTHDAVRRALGLLQAWLADE
RLLSVPLVLVAHPGDVSAAAVGGLVRSAQAEHPGRLLWVECHDGDLSQLLAAVAAGERAN
EPHVLVGPDGPRAPRLLPALDAGRETGLDPASTVLVTGAGGLLGGLVARHLVAAHGVRHL
LLVGRHAITGFDDLDAEVTTAVCDVADREGLAAVLARHAKARPLGAVVHAAGILDDGVLT
SLTPDRVSEVLRSKVDGAWNLHTLCRDVPVFVMFSSAAGVLGGAGQANYAAANAFLDALA
RERRAQGLSGQSLAWGWWAPPSGMTGHLAEGDRDRLARGGLAPMTAREGTALFDAALRSD
EPVLVPLRLDQAAPTVGVPPVLRGLVRSRGRRHTPSRAPSDGARRRAEDLRDRLARAAEP
ERLRLLTDLVRAHAAAVLGHPGPDHIAEERSFLDSGFDSLTAVELRNRVAAATDLALSPT
TVFDRPTPRLLAAHLADRIAGTEPERAPVPAPPVSDEPVAIIGMSCRLPGGVTTPEELWE
LLRDGRDAVSGFPADRGWNVADLYDPTGERVGSSAVREGGFLHDAADFDAGFFGISPREA
LAMDPQQRLLLETGWEAFESARIDPLSARATRTGVFVGVMHHDYAARFTATPDGYEGYLG
NGNAGSLASGRLSYTFGLEGPAVTVDTACSSSLVALHLAVQAVRRGECAQALAGGVTVMA
TPSAFVEFSRQGGLSSDGRCKSFAQAADGTGWSEGVGMLLVERLSDAERLGHRVLALVRG
SAVNQDGASNGLTAPNGLAQQRVIRQALEDAGLAASEVDVVEAHGTGTRLGDPIEARALL
ATYGQERARPLLLGSLKSNIGHAQAAAGVAGVIKMVLSMRRREVPASLHVDEPTPHVDWD
SGAIRLVIGHEAWPDTGRPRRAGVSSFGISGTNAHLVLEQAPEPTARPDREPTASGPVPW
LLSARSEAALGAQARRLAPYAQGRDAADVALSLATTRAVLRHRAVVVAEPGEHGSTLEAL
ARGETPRGAVTGTPVAGGLALLFTGQGAQRAGMGRELYAAHPVFAAAFDAVAARLGGVPL
DDGNALDRTVHAQRAIFAYEIALYRLLRSWGVEPAAVAGHSVGEVAAAHAAGVLSLDDAC
VLMEARSRLMEEMRAAGEMFSVRAAEAEVAAGLPPGVCVAAVNGPRSVVLSGDAGAVERY
AQRWPEPRRLRVSHAFHSHHMDGMLDAFADVVRGLSFSPPALVMPGDVEDPEYWVRQVRE
PVRFMDALRRLDAAGATTFLEVGPDAALTAVGPETLPDAAFVAVAHRRDPGERRTLLDAL
ARLHVRGQAVDWGRMFPDARRQDLPLYAFQRQRHWLSAQGPSPRNGWWYRAGWEPLPEPV
APRLTGTWTVVAASGDHDTAVDRALAAHGAEVRRVRSPEEVRGTHPAGVVSLLGRPASAT
GALADTLALLRAGTDAPLWCLTQGAAAVDGTDDDVSPEQAAVWGLGRTAALEHPDRWGGL
VDLPAEFDESTARRLAGVLADGGEDQVALRGDGAYGRRLRPATPDGAAWRPSGTVLVTGG
TGALGAHTARWLARNGARHLVLAGRRGPDAPGARALAAELEEAGSTVTLSACDVTDRDAL
RRLLAEHPADAVVHTAGAADHTTLADLTPERLDDVLSAKVDGARNLHELCGDVSAFVLYS
SMSGTVGSAGLGAYAAANAWLDAFARQRRAQGLPATSLAWGPWAGEGMSAGESGTRNERL
GLPPMDPARAVEALAAAAGGEHPCTMVADVRWDTYAAGFAVRRPSPLLAGLTQDRSSSRG
GSAWLRRVSGLPAAERGPALLTLARTEAAVVLGHAGPEEVPAGTAFRELGFDSLAAVQLR
DRLGAATGLELPAAVVFDHPTPAELAEHLRLALFGEDPRAPGGAGEEARLRQLLATIPLD
RLRVSGLLDPLLALATNDAPAAAPAGAEESDIDSLSPEDLLRRVLDQTS
>A0A2K8QYH8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MTHANEEKLVDYLRRVAGDLHETRQRLRELEDRSQEPVAVVGMACRYPGQADSPEELWRL
LASGDHAMGEFPADRGWDLDGLFHPDPDHPGTSHAREGGFLYDADQFDPEFFGISPREAL
AIDPQQRLLLEVSWELLERAGIDPAVLKGSSTGVYAGTALPGFGTPHIEKGAEGYLVTGN
APSVLSGRVAYTLGLEGPAVTVDTACSSSLVSMHLACQALRQGECTLALAGGVTVMAIPN
VFTEFSRQRGLAPDGRCKAFSADADGTAFSEGVGLVLLERLSDARRHGRRVLAVIRGSAI
NQDGASNGLTAPNGPSQQRVILQALANARLSPAEVDVVEAHGTGTRLGDPIEAHALLATY
GRDRPDDRPLWLGSVKSNIGHTQGAAGVAGVIKMIMAMRYETLPATLNVDEPTPHVAWDT
GAVRLLTEAVDWPRGERPRRAAVSSFGISGTNAHLLLEQPPADESSADEPPAGVSPADES
SADESSAPDRISGAISVDTEPSGQRVVPWVVSARTGQALRDQAGALATYLTDHPDLPVAD
VGWSLARTRSAFEHRAVAIGEDRDELLTAVRALAEGRGHPGLTLATAPTRSGGTAFMFTG
QGSQRPGMGRELYRAFDVFATALDDACAQLDPLLGHPLRDILFAAEDTDKARALHGTGVT
QAALFALETALFRLVESFGLTPSFLTGHSVGELVAAHVAGVLSLPDACALVAARGRLMQA
LPSGGAMAAVEATEEQILPLLAGRADRVALAAVNGPTSVVVSGAAETVDEIARTLKERGH
RTKRLRVSHAFHSPLLDPMLDDFREVTRRLTYHAPRIPVISNVTGRPSDPEQLRDPEYWV
RHISEPVRFHDGLRTLHGEGVTRYLELGPDAVLTTMAQDALAAETTAPDTSDGEPVFATV
LRPGRDEPRTLLTALALMHIDGGAVDFAAALPEDAVHVDLPTYRFQRQRYWRPVPNTTAD
VRAVGLGATGHPLLQAVVETPDGGLLLTGRLSPHTHAWLADHTIADSVPLPGTALLELAL
LAAARTGSELIDDLTLETPLILPASGAVRIQLAVTPPDETGRRTVTIASRPADEGGDALD
APAAWHHHATGVLSDAITPPPDDGPRTTAWPPAGAVPVDVADLYERLAAQGYAYGPAFRG
LHTAWRLGEEMFAEVRLAPEQRAEADGYGLHPALLDSALHPVEELMGGGHAPDGAEATVR
LPFTFGGVRLFATGATRLRVRITPTAADTLTLRLTDDHGAPVATIDALGLREVRADRWRS
ARAATADAPLYRLDWQPYPISADSPPSTASWALIGPRDQAAAVPDLTAHPDLDALRAALD
GGQPAPDIAVLECPGAPDTSAPDTSAHPDETPARVRAVVHHILGALRTWLMDERFSGTRL
VIATRGAVATGPGDGPADLATAPVWGLVRAAQAEHPERILLLDLDDDPASRDALRTALPA
AVAGAESEVAVRAGTALVPRLVKVRPERDTPPRALDPDGTALITGGTGALGRLVARHLVA
AHGARHLLLVSRSGGITEDIDAFADELTALGAADVRIAACDAADPEALAALLATLPEAHP
LTAVIHAAGVLDDGVVTAMTPEQLDTVLAPKLDAAWHLHRLTRDMDPAAFVMFSSAASIM
GSGGQANYAAANMFLNALAEHRRAEGRTAHALAWGLLASAGGMTGHLDDADLARMARSGV
APVSNEQALTLLDTALTTDHPTLVPARFDLAALRTRASTGPLPPVLRRLVHTPTRAARNT
VTSSLAGRLADLPPEEQDRLIGELVRDQVATVLAHPAPEAIELGRAFQDLGFDSLTALDL
RNRLNAATGTRIPATVIFDYPTPDALVRFLRERLVGAPARTPLPPTATPVATDDDPIAIV
GMACHYPGGVGSPDELWRMVADGVDAIGEFPADRGWDLGRLFDPDPDHIGTSYAREGGFL
HEAPRFDAEFFGISPREALATDPQQRLLLETAWQAFESAGIDPVSLRGSRGAVFTGVMYD
DYGSRFLGRTPEGVEGRLMTGSTPSIASGRVAFTFGLEGPAVTVDTACSSSLVAMHLAAQ
ALRQGECTLALAGGVTVMATPNTFVEFSRQRGLAPDGRCKPFAAAADGTGWGEGIGLLVL
ERLSDARRNGRDVLAVIRGSAINQDGASNGLTAPNGPSQQRVIRQALATARLSPADVDAV
EAHGTGTTLGDPIEAQALLATYGEDRPEGSPLWLGSIKSNIGHTQAAAGVAGVIKMVMAM
RHGLLPVSLHIDEPSPHVEWNDGGVRLLTEAVEWPRAERPRRAGVSSFGISGTNAHVILE
QAPDQAHSTEPDPDPDPGPDPDPGPDPGPGPGPGPDGLRVVPWVLSARGAEALRDQARAL
AARLTTGPTASAAEVGWSLIRSRTLFDHRAVVVGESRAELMAAVEALAADETHPGVVHTG
AAAATGGAGPVLVFPGQGSQWIGMGAGLLDASSVFAARVAECERALAPYVDWSLTEVLRG
VAGAGDLSRVDVVQPVLWAVMVSLAAVWAGHGVRPAAVVGHSQGEIAAACVAGALTLEDG
ARIVALRSRALRQLAGGGAMASLGVGQERATDLLSGLGDRAAAVVVAAVNGPASTVVSGP
PEQVAAAVAACRDTGERARTIEVDYASHSPQVDEIADELTELLKGVEPLEPPGSGVGFYS
TVTGGRADASILDTGYWVRNLRERVRFAEAIQALLADGHRVFIEASTHPVLTVGMQESFE
EAGVPAATVPTLRRDHGDLAQLVRSLAQAFTAGAEVDWTTLFPTDPAPRTVPLPTYAFQR
ERYWLEGTAGRGGDPADLGLVSAEHPLLGAAVELADGSTHLLTGRLTAGGGESWLGEHVV
AGARLVPGAAQVEWALRAADEAGCGTVEELALQLPLVLPDTGGLRVQVVVGEAAEDGRRD
VRVYSRPDRDAETTADPVWVCHAVGVLGPHGEPAPQPSGVWPPVGAEPVDTDGFYERATA
AGYGYGPAFQGVRRLWRDGADVLAEVALPEPAGGQAGFGIHPALLDAALHPASLLDRPME
EHGEDPAEEHGEKHGEAQREGHDDGRVWLPFAWHGVSLWAAGATTVRVRLTPHEQAAEGE
RALRLTVADAVGDPVLTVDSLVLRPARTDQLRTAGRGAVDGLFTLDWTPLPEMAPGADTG
LPEPVAGDGGWVALGAEGVEWAPPDVVRHPHLESLVAAIDAGTPVPSVALTAVPASKTAM
DIEAAETDALAAVRRTLDLLRGWLAEPRLAESRLVVVTHGAVAPGGPVAEDHGSGAVDTA
GAAVWGLLRSAQAENPERFLLLDRDPHGAPDPDEIGAAVLDGVLRAVALDEPQVAVGSDR
VWAPRLTRAGGPGSGGLVGPVGEPAWRLAVRGASTVDNVTPVPCPEALEPLGPGEVRIAV
HAAGMNFRDALIAVGMYPGGGVFRGSEGAGVVVDIGPEVAGLAVGDRVMGLFEGAFGPWA
VADARMVVPIPDGWSFRQAAAVPVVFLTAWYGLVDLAGLRDGESVLIHAATGGVGMAAVQ
IARHLGAEVYATASPGKHTVLEEMGIGQAHRASSRDLDFEEAFREATGGRGVDVVLNSLA
GPFVDASLRLLADGGRLSEMGKTDIRDPERLAAAHPGIRYRAFDLVPDAGPDRIGEMLCE
LGELFGAGVLRPAPVRPWPLDRARAALRRLSQAKHTGKLVLDVPAAVDPDGTVLITGGTG
TLGAYIAEHLVRTWGMGHLLLVSRRGPDAPGARDLAARLEELGARVRVAATDVTDASAVA
DLVAGIDPEHPLTGVIHATGVLDDAVVTAQTPERLARVWTAKATAAAHLHTATSHLRLGM
FVLFSSAAGTLGSPGQANYAAANAFCDALAAHRRAAGLPGVSIAWGLWADASGMTGHLAE
ADLARMSRTGVAALSTRHGLALLDAAVQHGGDHLVAAHVDPRTLAGLPADSLPATGGAGT
GRRTAAAAGEGRQVDWGARLAGLSTAEQHRLVLNLVRGHAATVLGHADVDAVQAEASFKE
LGFDSLTAVELRNRLAAATGLRLPAGLVFDYPEATALADHLLERLAPGDGPAPGRDAVDP
VLGELARLDTTLATLATDDEGRERIAKRLGALLAKWNTGGSGDPAGATGFDALEAASDDE
MFELIDRELP
>G7M3G4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Clostridium sp. DL-VIII|TrEMBL
MKDNNIKMSISCGKPITNKYCNKMNIGNLLIEAAENKKDKGILLVQGNDSDIFLSYEEIF
EKAMLCLGALQEKGIKQDDFAIISFQNNIDFIICFWACVLGGIVVVPISTPSAFKGKNAS
LEKLINVWNTLEKPVIISDASIIKGMKNNELYSECQEMNMLDISILRENTIKGKMNLSEI
EKTAFVQFSSGSTNTPKGVILTHKNLLTNIEGIIESGGLTSEDRVLSWMPYYHDMGLIGF
HISLIALGMFQINMNPMKFVKRPTLWFDLISKHKITMTSSPNFGYRLLLRKVKDKHLKEW
DLSSLRLIFNGAEPISMPLVNEFMEKLSECNLSETSMFMVYGMAEACLAVAFPPVNSKPL
SHFVSRNSLVNKSKVEEVEECAKDALQVADEGYPVAGMQVRVVNDEGEIVSENVLGEIQI
KGDNVTKGYINNPEATAKSFQDDWLKTGDTGFIIDGRLCVTGRIKDIIFVNGQNFFAHDI
EFKLEEIEGVETGKVVVGGWHDEKEGREKIAIFSSLRVKEDELKSFYGNMLSKISETFGI
YIDFVVLVKAIPKTTSGKVRRFLLVQSFLDNEFADSTLTSAELLLNIEEKAEEADEDESL
VLNISRDKIKEIWADVLERPAQSIGYNQSFFSLGGTSIKAVQVLGVLEDELDITLGHDIL
INCRTINEMEEYLKSFSESNSILTNIDEKISGEVEEEDGIAVIEMSCRFPEASSPEEFWN
NIVSGKCSISEVPEERWDVNQYYSTSGDPTKTYCKTGAFIDKPFDFDAKFFNISDEEAAV
MDPQQRIILELVFEILERAGYSKKKVSGESISLYIGAGTNTYQEYHFNTLNMSSLKNFDS
FNSLSKEVQESILEEWKNKLGVTEFHTNLLVDNILNMIAARTSQEFNFKGPSMVVDTACS
SSLVTIHLACEALKKGECELAIAGGINLLLTPTPYIYLSNAGALSTSGISRVFDAKADGL
VPGEGAGLVLLKPLKKALKDKDKVLAVIKASAINNDGHSIGVMAPNPDGQREVIESLYVK
SGINPRDIQYIEAHGTGTKIGDPSEVRALSNAFKRWNPESNSMAIGSVKANIGHLLNGAG
IASFIKVILAINNKTMPPNVNLDELNPSIKFDKTPFYTMLEARKWEVQEGKMRKAAVNSF
GFGGTNCHMVLEEAPSEIIPAVEVQDYSRNKYALNLSANSEKSLQLKINNLVKYLKTSKE
NNLGDICYTENALRTSFNKYRYSVVSESIEDLINELQNIKVEELNSDAQHKVALMFTGQG
SQYVGMGRELYNKLPIFKGYVDECSEVFYPYLNEKITDLIYSDKADESILAQTNITQPVV
FTMDYAFGRLLIDLGIKPAYMLGHSVGEWAAACLADVITLEDAAKIVSARGKLMGSIKSS
GCMCAVFTSSEKLEILFKEFEGAVWIAAYNGTHQVISGDEADVEKFCNNLLKEGIGFKKL
KVSQAFHTPLMEPILDAFREVLKEVKFNSPKIPVISNVTGKIMDEAFDTEYWINHILSSV
KFEQSIKYLSYKAVDVLIECGPDRVLSRMASGVQAQSARTILSLSDRKMESFDVCLAALS
SLFTLGFNVDFEKFESEIYYNKLQLPSYPFERKTYKPDFGDESIRVPDEWFYNWNWKPEP
HKYADSEIKGNIVIFSDNSEIEDEFEEIFKTNKIYVVKVGTEYRFDDYSKFIINPIAEED
YVKVFNIIQGPVGAVIHLWNLNKESFKLEFAFDDKVMHEDIYSVLYIGKALSKLNIEKTK
LLLVTNNGVSVNEENKISSPHQASAITLAQALDQENAFIDSYCIDVDKKEYESNREIAQI
LSDEIKHDLSKEGIVAIRGGVRFIRELSDAIKFNQTSKIKFNDGETYLITGGASAVGSEI
AKVIAKKAKINLILTGREELPLIEKWEEELANNTRYAKKISIIMELKELGANVIYEAVDV
TKIGDMKALVERIADEYGAIYGVIHAAGTFDSKTLKLLDKNIKVINKIIEPKLKGGIITD
LVTRKEPLKFFVMLSSVSCSEKLWSAGVGDYAAANAFLSAYSYYRAADNAPGKTIALNYS
LWAGTGMGSDFGNGALLALKAQGLNPLPAKKAAEAFIRALSVESQNVIHIIDKIEISDVE
KSSTIKMPQVNSRKLKNIKEIVYKVIAKQLKVEEDNFDVGKNFLELGLDSLGAVKVMEML
GTSIGMELYPTLIFEYQTPQALAEYIEMTYLEGFEEAAVSKINDLDTEVIETERSKDIAI
ISASLRIPGANNLNEYWRILENGECVIREIPEDRWPANDHYSEDMNSAYTSYSKCGGFID
NPYEFDPLFFGMSPSEATVTDPQQRIFLEIAWEVMQQAGYGGRYSTNNIGVFVGSEQNGY
SEHFNNYRIYMELKDKLLKNQTFNNMESNEKSEIMSNILNVLKPAKMVPDAVAGNSLNEV
AARVSHCLNLSGPSLTVNSACSSSLSALHLACESIRTGQCKMAIVGGVNLNTSPTPFIGL
SRVQALSKTGACYPFDDRADGMVLSEGASAILLKPLEDAIADNDNIMAVIKGSAMNNDGH
SQGITAPRPQGQADAVIKAYLDAKINPETVSYVETHGTGTPLGDPIEIEGMAKAFRAFTS
EKGFCAIGSVKSSIGHMLSASGITSLIKVVLALENKKIPHTINYNKTTTNRNIDFANSPF
FVAAEKTMEWERSGVTPLRAGVNGFGFGGTNVHVILEEAPEKKNIEKGEEDFPYLLQLTG
RNQSVIKNIALNLKEYVKGHEGLNTASICFTINSNQKELSTKNSAVVESKEHLLEILTHL
INNEDSECIYKGRSNPNRQTEAYLILDGNMKKVEKCKEDLSSRFDAFNIAYKECLKVVEK
NISNEEILDFESFAVQYAFGVLLSNFEMKIYGIIAEGTGILAASVLTGKMSLKQALEEIV
GTIRAEKDDVLEGDKNAVYLNCSILTSTGVLEDVFNVSQNDDKNIKSLNVFANKNQVIIY
PGNFNEIKNKEFYDDKNFNWINMDITRNPVKSIMSAFAKIYTLGVRFNPSKLFKGNIKKV
MLPTYPFENETYKVSFEEELTYKEADYISMQRNGLRKMEMKHALSNSEKRSISNQLAIDI
EK
>A0A2K8RA83|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MATANEAKLREYLKKVTTDLTAAHRRLQEVDDQAHEPIAIVGMSCRFPGGVSSPEELWQL
MVSGGEAQTEFPADRGWDLQNLFDPDPDTPDTTYTREGGFLDDATRFDAAFFGISPREAT
AMDPQQRLLLETSWEAFERAGIDPASLRGSRTGVFAGMNASDYLTVAIDAQDDFGGHLGT
GNASSVVSGRLSYVFGLEGPAVTVDTACSASLVALHLAVQSLRLGECSLALAGGVHVMST
PGLFIEFSRQRGLSEDGRCKAFSADADGFGPAEGVGVLLLERLSEARRNGHKVLAVVRGS
AVNQDGASNGLTAPNGPSQQRVIQQALAGARLSGNDVDVVEAHGTGTSLGDPIEAQALLA
TYGQDRTEEQPLLLGSVKSNIGHTQGAAGIAGVMKMVLAMEHGVVPESLHIAEPSPHIDW
SSGKIALVRSATPWPETGRPRRAAVSSFGFSGTNAHTILEQAPAEEPGPVELVSKQPGVL
PWVLSGKSEAALRAQAWRLLDRLHDEPALRPVDIGLSLATTRAALDHRGVVQGRDREELM
AGLTALAEGGMAAGVERGSVVAGQTAFVFPGQGSQWVRMGVGLMDASPVFAARIEECAGA
LGEFTDWSLVDVLRGAEGAPSLERVDVVQPVLFAVMVSLAELWRSLGVVPAAVIGHSQGE
IAAACVAGALSLRDAARVVALRSQAIGRVLAGKGGMVSVALPVVEVRERIASWGEERISV
AAVNGPSSVVVSGEPTALDELLASCETDEVRARRVPVDYASHSAQVELLREELLELLAPV
QPKNAQVPFLSTVTGEWIDGPELDAEYWFTNLRRTVELEGAVRRLLDEGFGVFIESSAHP
VLTMGVQETAEDAGVDAAAIGSLRRDEGGLDRFWASVGEAWSRGVNVDWDAVFDGTGARR
VELPTYAFQQQRYWPEAAPARAAGEIGHDAVEAKFWAAVEAEDWQALAAELTVEGDQPMS
AVLPALASWRKQAREQSAVDGWRYRVTWKPLAEERSPRLSGAWLVVVPGVPATENTDTWT
DAVAGVLAERGADVRRIAVDTGVDGREELAERLRAALADADGTPFAGVVSLLAPAEGAHP
EHPSLPAGTAAQLALIQALGDAGIGAPLWCLTRGAVSVGGSDRPASPEQALVWGLGRVAA
LEHLERWGGLIDLPETPDERALTRLVGLLASDGDEDQAAIRAAGVFGPRLVRAPLADTST
VRSWKPTGTTLVTGGTGRLGAQVARWLARNGADHLVLASRRGPEAPGAVELEAELTGLGA
KVTLAACDVTDRAALAETLAAIPADQPLTAVVHTAAVIEDGVIEGLTPDQAERVLRLKVD
ATRHLHELTRDLDLTAFVLCSHFSATFGAPGQGNQAPGNAFLHAFAEQRRADGLPATALT
FGPWGDGGTVDGAVGDRMRRHGINEMAPEPATATLQHALDRDETALTVIDMDWRRFTLAF
TADRARPLLHDLPEAREVVEEMAAAETEGTGAAAGAALAGQLAALPETERERVLLDLVRS
AVAAVLGHSGAQAIEAGRAFKELGFDSLTAVELRNRLGAASGLKLPPSLIFDHPTPAAVA
AYLRAGIAPDEAADGTAVLDELDKLETALTGTAPDNITRARITMRLQSLLAKWNESDGTA
VTAEPAAAAAAPERPAKDTVDAEQLQSASDEELFAFINKGLGRA
>A0A2K8QUX9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MPTTAEQLHHLSAEQRARLAARLRSKYDRKDTSEPIAIVGMAARLPGAANVTEFWDLLRT
GDSAVGPPPPGRQGDRPGGYLSDIAHFDAEYFQISPREAVSMDPQQRLLLETASDALHDA
GIEAGSLAGSRVGTFMGLMHDDYGRIGAEQGHIDGHFVTGTNPSLAAGRLAYVFDFHGPA
ITVNTACSSSLVAMHLARQSLLLGECDLALSGGGNLLLHPDSTLMYEQAGALSRTGACHT
FDASADGYVRGEGVGVVVLRRLSDALVAGDVVHGVVRGSGVNQDGRSVGLTAPSGEAQWR
LVSGVVEGAGLRAGDVGYVQAHGTGTRLGDPLELRALARALAVGRGEGGRLAVSSVKTCV
GHLEAAAGVAGLIAAVLAVREGVIPPHRHLVRPNPLVAWDGLGVVVPSVAMPWVVTDGPR
RAAVSSFGISGTNAHAIIEQAPRHHPTPRRVTPKPARRQGEYYWWPRHERQPELVASPEP
GCYRTRWQNIGRPAPTRARGRWLLLGDDTVTAARLRDRLERDGAHVLVVGRRDEEHPWPM
DAVRDALADEAVDTVVCLTAGAGPSATAADEDGEAALPRVLRTSTAVLDLTRTLARLRPS
AQLVLVTHGGRAGEGTPERAALWGLGRVISSEHPELRCRRIDLTAGDDEALADELAASDA
SEDEIALHEGMRHAARLVEHRPGTEADTAGRGEPVVRRDGTYLITGGGGALGLHCARWLV
DGGARQVFLTGRSHRPPPAAERAMAELSGNGVLVSYIPADVSRAADCDRVFDQLGSTGAP
LHGVIHAAGVLDDSLLLHAGHDQLARVLSPKVAGGRNVHRAALRRDQPLDFLVYFSSQAT
MLGTVGQGAYAAANAYLDGLAEYGQAMGLPALSVAWGPWTGAGMAGRAPDSARTLWESSG
IGMIDPAHGLASLERLIHDRAPSTVCVSVDWRRYAHHMGGRTPARLRGLARPEAVTRPTD
EDVAAVLERELRQVLRLRPQTPVDADRPLMELGLDSALAVELRNRLTGELGIPLSTTVTF
EHPTVADLTEHLRAGGDAEIYERATPAAVPRPTACRAAPPAPEPTRVKEPAPVDGGEDAV
AIVGMACRFPGGADNIASYWQLLREGRDAIVDVPPDRWRPEDLPGRNGEPPDGPLRRGGF
LTEPVDAFDADFFGLSTHEAQRLDPQQRLLLETAWEALADAAVVPHQLVGRQGGVFLSLY
YNDYAQLAAEAGVSDAFSSLGNLNSLAAGRLSYALGLHGPSLVVDTACSSSLVALHMARQ
SLLRGECDIAFAGGASLMLTPGASVALGQMQAVAADGRCKTFDASADGFGRGEGVGVVVL
RRLSDALVAGDVVHGVVRGSGVNQDGRSVGLTAPSGEAQWRLVSGVVEGAGLRAGDVGYV
QAHGTGTRLGDPLELRALARALAVGRGEGGRLAVSSVKTCVGHLEAAAGVAGLIAAVLAV
REGVIPPHRHLVRPNPLVAWDGLGVVVPSVAMPWVVTDGPRRAAVSSFGISGTNAHAIIE
QSPRPHPAPEPAADADGPNVLLVSAKSPEGLRSLAARYASHLESTGDSLADIAYTSGVGR
AHLPYRLAVLGETAEAVREALGSATRGTRHAQLITGEATGEPGRVAFLFTGQGSQYAGMG
RELYERYDVAREAMDTCARILDDSLPRPLLPTLLDPARGEVLDRTQYTQPALFTLQYALV
RLWESWGVRPDIVIGHSVGEFAAAHTAGVLSLPEALGLLAERARLMQTLPEGGTMASVFA
DPDTVAEAMAHTEAGTVCVAADNGPSHTVISGHRPAVEQTIQALRAQGVRCLSLKVSHAF
HSALLDPILDDLTAAARAVTHRTPRIPLISNLTGGEIRTAAEMSGDYWSRHARGTVRYRQ
GAQHLADVDHLVEIGPAPTLLQLTRGCLPGASVKCWLPSLHPKHQAPRQLLMSAAALHTH
GLPLDWEAVHRERRPSKVSLPGYPYERRRHWIPRPAPVAPANGHGAGESAGDDALVGTGG
PSPLTDTTVFAVEHSTTAPALLAGHLVYDTVVVPGAVHIARALAAGVRILRTGPVAAERV
EFTQAMSLREGDLRRTHTVVTPDADHEREWSVRVASSDARGTTGREAEDWTLHARCRLRA
ADPVADFADPSQEIRNRCPEVVDDSSFYTRFAQHALTYGRDFRWIRRVRRAPGEALALIR
PDEPTDHLADYRCHPGLLDSLLQLLVFALPEAFGAAEPGQAMVPVAVERVVSYDVPGGEL
WAHAVAHHGPAGASDGRGDITLRRAGGAPVLRLEGVCLRPAPAATLLGGRDAGERSPAGA
GRATEPLLRTYHTGFRRLDQAEPSAAARRWLLVGGEPERAGRLADLLRSRGQDCRVEPAL
PMSLPHGSWDVVCLDAGVPGPEPGRGRYDTVRDVVDAVHRLTGSAEGHRLTLLTRQALAH
RPEDAVRPEAAALWALGRVVANERPELGCRRFDIAADGDLDALVGELLLDRPDDEVVVRA
GVAYATRIAVAPEPADPAAARLSPDGTYLVTGGFGAIGRLTAETLLARGAGRVALVGRSG
PGHEGDGSTPLAGDKRVRACACDVSDPDACRELLVKLRDEGPPLRGVVHAAGVLDDDGIE
RLTWQRFAAVLAPKADGAWNLHLATRDDPLDFFVCFSSLAALLGTVGQANYAAANGFLDG
LAQLRRSQGLPGTSIAWGPWDVGMAARLSAPVRAHLRRIGLTAGGTGESLAAFEALLFGE
RAHSAVGRVDWDAATTALRLPRARDLTAGPRQESTEWSTIPATERRPFIRHLLGEHLAEL
MGSSATDAVRPAPAGGNEDDDTALADLGIDSLLGMELRGRLSDSLGVPLPVTLIYDHPTV
GRLTAYLCGLPARSSNEGTNQ
>A0A5B7ULK3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MPDNDKLLEYLRRATADLGDARRRLREAEDARHDPVAIVSMSCRYPGGADTPEALWDLVD
SGTDAITEWPAGRGWDTEALYHPDPDHPGTSFTRHGGFLHRAGDFDAAFFGISPREALAM
DPQQRLVLETAWEAVERAAIDPEALRATRTGVFVGAMRNDYGSTSRHVPELQGLLDTGTA
ASVVSGRVAYTLGLEGPALTVDTACSSSLVAVHLAVRSLRSGECSLALAGGVAVMATPDA
FVAFSRQRALSADGRCKAFAAAADGTGWSEGVGVLVLERLSDARRNGHQVLAVVRGSAVN
QDGASNGLTAPNGPAQERVIADALADARIAPGDVDAVEAHGTGTRLGDPIEAQALLATYG
KHRPAERPLWIGSLKSNIGHTSGAAGVGGVIKTVMALRHGRLPRTLHVDEPTPFVDWSEG
AVRILAEPRPWEAPGRPRRAGVSAFGVSGTNAHLVLEEETPQDLADPAPDATAPEPATGP
LPWVLSARDEDALRAQATRLLAHIEGTDAGAGTGEDTTAGAIGRALATTRTAFEHRAAVV
ADDRAGFVDGLTALASGGTAPHLVRGTTGPDGKTAFVFPGQGSQWPGMAVGLLDAEPVFA
ARAAACERALAPYVDWSLEAVLRGADGAPSLDRVDVVQPALFAVMVSLAELWRSYGIEPD
AVVGHSQGEIAAACVAGALSLDDAAKVVALRSRALADLAGRGGMASVPLPAADLGPHLEP
WGDRLSVAAVNGPATTVLSGDPEAVEGVVAALVAQDVRARVIPVDYASHSAHVEAIEERL
LTALADLAPRPADVPFHSTVDAAPLDGGAALDAAYWYRNLRRTVRFEEAVRGLLGQGYSH
FVEVSAHPVLTIGVEQTAEAADLERPVAVLGTLRRDEGGRARFLLALAQAHTRGLFPDWS
RVFAGHAAATGLPTYAFRRRPYWLEPESAPAPAAAPPADPVADRFWEAVRAGDLPELTAT
LGVGPEEPLSAVLPALAAWRERRAALTTVESWRYRPDWQPLPEAAAARLRGTWLVLLPAP
LALDPQSLACVRALQDAGATVVSAALDVAALDVADPDVADPERGPLRDRLADVLRDLLRD
ALSDAGGAPAGVLSLLATDERPHPRHPAVSVGTALSLALVQALGDAGVDAPLWWATRGAV
AVGPADPPVRPAQHAAWGLGRCAALEHPRRWGGLLDLPPELDPRAASRLCAVLAAPGDED
QLAVRGTGVHGRRLVRAPLGDAAPRRAWTPRGTTLITGGTGGLGAYIARWLAREGAEHLV
LISRRGADAPGAAELAAELTELGARTTVAACDITDRHALATLVAGLVADGCEIRSVLHAA
AGGSLVALDDTDAAEFADTLHAKALGADHLDALFDRDTLDAFVLFSSISGVWGSAIHGAY
AAANAHLDALAENRRARGLAATSVVWGIWSPEDGGGMAANLAEDQLRAQGVLFMPPATCV
TALKQVLDHDETLVLVADIDWDRFATVFTTSRPSPLIGTVPEARAALAPDPAPADTAEDP
SRGLRAQLRDLTGPERERALSDLVLTEAAAVLGHDAPEAIAPERAFRDLGFDSLTAVEMR
NRLTAATGLRLPVTLVFDYSSPGALARHLRAELLGDRTPAATAPVVRAAQADDDPIVIVS
MSCRYPGGVGTPEELWQLVAEGRDAVAGLPADRGWDLDALYDADPDRPGTSYAAAGGFVY
DAGHFDAGFFGISPREALAMDPQQRLLLETSWEALERAGIDPHTLRGSRTGVFAGAAYQG
YGGSMDDVPEELEGLFVAGISTSVLSGRVAYTLGLEGPAVTVDTACSSSLVAVHTAAQAL
RNGDCSLALAGGATVIGSPLTFTGFSRQRGLAADGRCKSFAAAADGFGMAEGVGLLLLER
LSDARRNGHPVLAVLRGSAVNQDGASNGLTAPSGLAQQRVITEALADAGLSAADVDVVEA
HGTGTTLGDPIEADALLATYGQERENPLRLGSLKSNIGHSQAAAGVAGIMKMVLAMRHEV
LPATLHVDAPSPNVDWSAGAVSLLTEAAPWPANGHPRRAGISSFGLSGTNAHVVVEQPPA
DEEPAGAEQGRPDTAVPWVLSARSPEALREQAVRLRAHVAARPGLGPADVGHSLATTRAA
FEHRAAAVGRDRDALLAALDTLIDGRTGPGAVRGTTAQDRRAVFVFPGQGSQWPGMAREL
LDSSPEFAARITACAEALAPYTEWSLLDVLREASEAPSLERVDVVQPVLFAVMVSLAEVW
RSYGVEPAAVVGHSQGEIAAACVAGALTLKDAARVVALRSKALRALTGRGGMLYIPLPPE
RVEARLAPWTDRLSVAAVNGPTTVTVSGDPEALGELHAALADDGVLCWPLPGVDFAGHSP
QVEEIHGELRTLLAGIAPRPSRVPFYSTVTGAALDTTALDAAYWYRNLREPVDFHRALGA
LIADGHRLFVETSTHPALTVWLQEALEAAGGSGGAVGTLHRGEGGRDRVLASLAELHVLG
HPVDWDAVFDGTGARRVDLPTYAFQRRHYWMRPAPRDAATAPVGTDPVDRGFWDAVAGQD
PDALARHLRIEDDDVRAAMSTVVPALSQWLHGRRGRTTLDSWRHRVTWKPLPQERAADLG
GSWWVAVPEAVAADPAVTACVEALREHGAHPVVVELGADDAGETGRGPLAGRLRALAQES
PADGVLSLLVLADAPYADGTALPVGLALTTALLQALGDAAVKAPLWCATRGAVAVGRSDR
LDAPLGALHWGLGGVAAVEHPERWGGLVDLPARLDARARARLAAVLAAPDGEDQLAIRAS
GVFGRRLAHAAPRTEPEGPAWTPDGTVLITGGTGGLGAQLARRLAGSGTAHLLLTSRRGP
DAPGADALAAELTSLGAEFTIAACDAADRDDLAALLAAVPAGRPLRAVFHAAGVLDDGVL
DTLTPERAAGVLRPKADAALHLDELTRDADLTAFVLFSSLAGTLGGTGQGSYAAANAFLD
ALAQTRRDHGLPATSVAWGLWGGDSLAAGATSERLVRDGLPAMDPELAVEALWQALADDE
TRLIVADFAWDRFVRAYTALRPSALIADVPEARGALAERAAAPGAAENALVARLAGLGDA
ERTQELADLVRALAADVLGHDDPAAIAPERAFKDLGFDSLTAVELRNRVAGATGLRLPVT
LVFDRPTTAALVDHLREELLGTAPAPTTAPVPAAAAATDDDPVAIVAMSCRFPGGVQTPE
DFWRLLADGTDAVSAFPADRGWDLEGLYDPDPEKVGRTYAREGGFLYDAAHFDPAFFGIS
PREALAVDPQQRLLLETAWEAFERAGIDPRTLKGSDGGVFVGSSYRDYGSRVTEPSEEFE
GYLGIGSAGSVASGRVAYTFGLEGPAVTVDTACSSSLVAVHMAAQALRSGECSLALAGGV
TVMATPGAFVEFSRQRGLAADGRCKPFAAAADGTAWAEGAGMVLLERLSDARRHGHPVLA
LVRGSAVNQDGASNGLTAPNGPSQQRVIRQALAGAGLAPGDVDAVEAHGTGTRLGDPIEA
QALLATYGQERETPLYLGSLKSNIGHAQAAAGIAGIIKMVLAMRHGALPATLHVDEPTPY
VDWTAGRVHVVTEHTAWPEGDRPRRAGVSSFGVSGTNAHTILEHVPDPAPPVAAPPTGRR
LPWLLAARGEDALRAQARRLLDRVTAAPERHPDAVGKALATGRTAFEHRAVLVAADREGL
LAALAALADGTPSTDVVEGATGRAGRTAFLFPGQGSQRLRMGAELYERFEAFADAFDAVC
AELDPLLDRPLRDVITAPEGSADAALLHTTAYTQPALFAVGVALHRLLESYGVRPDLVTG
HSVGQLAAAHVAGVLSLPDAAALVAARGRLMQAMPGGGAMVSLTVPEPDLLPQLAGREGE
IAVAAVNGPAATVLSGDAAPVEEIAAHWREKGHKTRRLTVSHAFHSPHMDGMLDDFRAVA
ERVTYHAPRIPVVSDLTGAVATAEELRDPGHWVRHVRSTVRFLDAVRTLEAEGATAYVEL
GPDGSLTALGQECLTGPADGVAAVPLLRKDAPEEAAFTAALARLHVHGVRVDWAPLFARV
PAGHVELPTYAFQRARYWLPPTPPTGDMPAAGLLPAGHPLLGAGAPLADTGGHLFTGRLS
VAAHPWLADHAVLGGALFPATAFLELAVHAGDELGCAEVDELTLEAPLTLPERGAVTLQL
TVQAPDAGGGRVFAFHARPEHAAPDEPWTRHATGRLSPGGHTPPEDLTAWPPAGAEPLDV
DGLYARLADGGFAYGPAFQGLCAAWRLGDAVYAEARLPEAQASDAGRYGLHPALLDSVLH
ALAFGVLEGSDQGWLPFSWSGVRLHAAGATALRLRMTPAGRDAVAWTVADPTGAPVASAR
SLVLRPVTADRIQESRTGTHADMFRLEWPALAVADTAPASCAVLGDALPGLAPAHADLAA
LGAAIEAGAEVPALVVTALPPTTGELAASVHELTASALELVRAWLADERYAGATLALVTT
GAVPVGPDDDVADPAQAAVWGLVRSAQTENPDRFVLLDTDGTPASDAALAAVLATALGTG
EPQLALRAGQPHTARLARVPGSTPARAPGWDPEGTVLITGGTGSIGALLARHLAGEHGVR
HLLLTSRSGPAADGADALRAELAALGADAEIVACDAADRAALEKVLGALEHPLRGVVHTA
GVIDDGVVADMTPHQLHRVLRPKVDAVVHLHELTADLDLSAFVVFSSIAGVFGGMGQANY
AAANAFLDALAHRRRARGLPAASLGWGLWATGGGMTGHLGEADLARIARGGIVAFTPADG
VALFDTATGLDAPALLPLRLDTGALAAQAAAGGVPAFLRGLVRTPARRAAAGEGPGPDAA
DALRGRLAGLPPAQRARVLVDVVRTHAALVLGFPDPAALSTEQPLLDLGFDSLTAVELRN
RLRAATGLHLPATLLFDHPTAAAVARHLADEIAPEDGTAGTGPAALAELERLEAAVRDGL
PDDAARTALTTRLQGLLETLRPGTGPDADAVEDRMGSTDDDLFAFIDNELGRP
>A0A5B7UM14|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MNVPESPAGTPLLWTLSAARRGALTAQARRLRDHLRALPEWSPADVGLALARAATATGRR
AALVAGDRDAFLERLDALADGRGAPGLAEGPAGPGGGTAFVFPGQGSQWPAMAARLLDSA
PRFGARVDACAQALEPFVDWSLMDVLRAAGGAPPLERPDVVQPALFAVGVGLAGLWRDHG
VEPTAVLGHSCGEISAAVVGGALSLDDGARVVALWSQAQATLSGRGEMVSVMAPLADVEA
QLGGYEGQVGVAAVNGPRSVIVSGDIDAATELTARLTAAGLHARRIAVGLAAHSPHIDAI
VPRLHADLAAVRPLTAHLPYYSGLTGDLLPEPALDAAYWARNLRRTVRFDRAAAALLRDG
HHTLLEISPHPVLTTALQAIAAEHGVTAHVGATLRRGHGDRTQFLTALGEVYVHGGATPD
PDTLCEGLDARPMDLPAELLEAGDDPGTEDPRTALRDELAPLTATAQRERLLRLVGHEVA
AVLGEPGPVDPDATFTGLGLDSVTAVEIRNRVAAATGAAALPVTAVFDHPTPRALAEALR
DELLGGARQEAPAEAPATAAHEDPVAIVAMGCRFPGGADTPERLWRLLADGTDAVTEFPG
DRGWSTAGACAPEDTGPGRHYQREAGFLHDADRFDAEFFGISPREALVMDPQQRLLLETS
WETLERAGLDPHTLRGSRTAVYIGAMTMDYGPRLHEATDGNGHLLTGNTGSVASGRVAYA
LGLEGAAVTVDTACSSSLVALHLAVQALRRGECALALAGGATVMPTPGMFVEFSSQGGLA
PDGRCKAFSAQADGFGLAEGVGVLLLERLSDARRNGHPVLAVVRGSAVNQDGASNGLTAP
NGPSQQRVIRAALADAGLSAKDVDAVEAHGTGTRLGDPIEAQALLATYGQERLEGRPLWL
GSLKSNIGHTQAAAGVGGVMKMVLAMRHGLLPRSLHLTEPTPYVDWSAGDIRLLAEPTPW
PESDRPRRAGVSGFGISGTNAHVIVEEVPQESVVAGACGVGGSVAWVVSARSPQGVRAQA
ERLLEVCGEEDVRISDVALSLVETRALHEHRAVVAGGREQLLAGLRALAVGEPSGCVVSG
GGWCVGTVFVFPGGRSGWGWRVGCWMSRRCLRG
>B8LZ55|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MAGTAVAFAEAPTTVNGMNKEASVHIYIFGDQTVSFEDTLRSLLNIKDNAALSDFFNKVG
LRLRSYIGGLPLHERDFFPQFTTLVDLFARHDQFAGAPALKFTLLCVTQIGQWIRYYGKG
PKVYPSPTSTYLAGACTGSFAVAAISTSRSIGELLSPAVEAVLIAFKTASYSLSLRKDLG
FTVSGGPNSWSVVVGVQESEAARLVENFNSAKGLPVVSSIYLSCMNRNNTSVCGPPELLL
EFLSSNSLKHLSLPIEIPYHAPHIFNASAPEKLVGPFSDVILEDYRQCFKSISIASGEVI
TSSSFRELLQRAVSETLLEPMRWDVTISSIGEELVQENFTSCDIYSVSSKSGQSLSSALS
QDAKLRVNISNSLEVSSGSSNVSSTGNFSDSDIAIIGYSGRFPESASNEEFWELLIAGRD
VHRTIPEDRFDWKAHYDPTGKTKNTSRVKYGCFVKEPGLFDARFFNMSPRECENCDPAQR
LAITSAYEAIEMAGLVSNRTPSTQQDRIGVFYGVTSDDWREVNSGQDIDTYFIPGGNRAF
IPGRISYFFRFCGPSLSVDTACSSSFAAIQTACAYLWRGECDTALAGGANILTNPDNFAG
LDRGHFLSTTGNCNAFDDTANGYCRSDAVGTVILKRMEDAIADNDPIFGVIRGAYTNHCG
RTDSITRPFEGDQAAVFNRIMRYAGVNPLDVGYVEMHGTGTQAGDATEMRSVLSVFAPFS
TRKFPLHLGTVKANIGHAESASGVASLIKVLLMMKHNAIPPHCGIKTKINHNYPTDLKER
NIHIPFQLTPWSREDMSLGKRLVFLNNFSAAGGNTAVLLEDAPVRNAKDGNDSRSKQPVT
VTGKTVKSLKGNIEKLIRYLDQYPDTSVSSLSYTTTARRMHHTYRAIVSGYDVESIRSRL
QKILESVSETKPIPTASKLPKTVLVFTGQGAAYQGLGKELFETAPIFRDSIIRFDNIAQQ
QGLPSFLPLVCSSSPDRPVHAYGPIVTHLALVCVQMALYTLWRAWGVTASATIGHSLGEY
PALYAAGVLTAANVIYLVGTRARLLTEKTTPGTHAMLAVKLSAVAIERELQGSGCEIGCF
NQPSNNVVTGPLEQLTQLQNRLKSRGVECMLLDIPYAFHSNQVEPILASFEKAASAVNYN
QLTIPYISPLLSKVVSPEDNGEFDCTYLTNACRQPVKFQDAIEAAQASSHVDEKTIWIEV
GSHPTCIGMIKSILSGQSPRVFGSLRKDTDDWTAIMPAIEGLYQSGFDIQWSEYHRGFEN
EQEVLGLPSYAWDLKNYWIQYRNNFCLTKGDDPVPTTSIASGSPVAQKRVPYVSPSVQRI
LEEDNGTDASTLVAESDIHDPRLAPILEGHVVNGAMLCPSSLYADVAITITQYMAKAIGI
YKDTTGLDVADMKVINPLILNKDCDAQLYQVVATAQWKQHIVSFKLFSVNNAGRKTGDHA
TFTVRITPNQNWIAEWQRQAYLIRSRISALQNSVKEGSAHILKRPLAYQLFSTLVSYNTD
YQGMQEVMLDSDEHEATTKVEFQVDDRGFKFNPCWVDSLGHIAGFIMNASDATPTKSQVF
INHGWDRMRCAINFEKGVEYQVYNRMQLESGTTYVGDTYIFKGNSLVGIYEGIRFQGVPR
QLLDRLLPSRKQTQQRAVSDKPPVQSSNRQPNPSAAQPTNVVSQKPTLAVKQKPVVSTAP
RPNEIASRVLTIIGEEAGVDPTELDPNEDFQNHGIDSLLSLTICGRIQEELGVEVPSSLF
ADYCTPLELSRFFGSDNNHTSSASSASSSDDTDGINTPDNREIDSDTSTEGETGNSILEV
IREMIAQETGVPVSELSLTSSFADLGVDSLLTLTIVGKLTETLDMDIPSNLLMECENLEE
VSKALGLQEPPLSLPAEPVLNTGKITKFSFDPHAGPQSTSILLSGNAKTANKIFFLFPDG
SGSATSYASLPKFGSDVVVYGLNCPYMKTPHAMTGTLEELTSKYLVEIRRRQPNGPYYLG
GWSAGGICAYEAAQQLAREGCKTEKLILIDSPNPVGLENPPQRMYDFFESIGIFGSGSKP
PPSWLRPHFDAFIRLLDNYKIRPVANSGFKMEVYMLYARDGICSDPSVPRPEIRPDDPRE
MIWLLNERTDFSGDGWASIVGRENLQITVMDKVNHFSMMDKGPHMEQFASFLHRALA
>A0A376RHF1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Escherichia coli|TrEMBL
MQQCASGAMVAVFADEDTLMPLARQFELDLAANNGTQHTVFSGPEALLAVFCATLSQHDI
NYRRLSVTGAAHSALLEPILDRFQDACAGLHAEPGQIPIISTLTADVIDESTLNQADYWR
RHMRQPVRFIQSIQVAHQLGARVFWRWGPMPSWLLAGSANTAITHTG
>A0A2P4US60|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinomadura rubteroloni|TrEMBL
MHEFHVAIGRLERAPLVLSAPDATSLRSAAATLAGEVRAAGNPNIGGLAADLAARDTAGR
HRAVVLAADRTQLLDGLDALAAGRSAPSLVTGAPPSARRPVLVFPGAGCQWPGMARALRD
ASPPFARRLDECARALDADRSPHTLPDGDPAWDRVEVCQPALFAVMVSLAELWRSFGVEP
AAVLAQCIGEAAGAYAAGALSLDDAALACAAAAEAQAGVAALGDMAAVRLPVPALAAKLK
RWGGRLWIAGVNAPDWTLVSGDRGARDELLAALDDEGVFATAVRTGAPTHTVRLDGARTA
MLDRLAGIAPRAGRVPFHSATTGTETDGALLDADHWHRCVREPIRFEEATRSALAGGPVA
LIECTPHPSLLTPMRDTAQADAGADAVVIGSVDRDDDGLDRFARSVAEAYCHGVAVDWAA
ALAPAPEPEPVAAEPDAPHEPIAILGMACRFPGGIATPEQLWDAVVEGRDLIGALPDDRG
WDTRKLYEPDSGKPGTSYTREGGFLADAAEFDAELFGISPREAAAMHPQQRILLEIAWEA
CERAGLDPLSLRESDTGVFIGAFATEYGPRMHEAGAGPGGYMLTGGTLSVLSGRIAYALG
LMGPAMTIDTACSSSLTSVHQAVGSLRSGECSLAFAGGASVLGTPGLLVDFSRQHALSHD
GHSRAFSADADGFGMAEGAGMLVLARLSDAVRLGRPVLGVIRGSALSQDGASEGLAVPDA
GAQELAIRRALEDAGLTAGDIDLVEAHGTGTRVGDPIEARSLLAAYGRSAGHPVFLGSVK
SNIGHSMAAAGVAGVIKTVLALRHGVLPKSLHAERLNPDVDWSRGHVRVLRENRDWPRTG
RVRRAAVSAYGISGTNAHVILEQSPSERAGGRAPQDVPGLPWVLTARSPEALRAQADRLL
RYVRENPDARAADVGWTLATARARLEHRGVVVGDDRAALVDGLAALAGGTDAPGLVRGAD
VHGARNVFVFPGQGSQWAGMAAELLERSPVFARRIAECDEALAPYVGRSLTGLLRAGVPE
DAGTDVVQPALFAVMVSLAAVWEDHGVVPDAVLGHSQGEMAAAVVAGALSLEDAARVVAL
RARALRVLAGTGAMATVALPPDAAAERLARHGRLSVAAINGPGEVVVSGDTDAVVSLLAE
LEAEGVWARRIAVDFASHSAHVERLRDRLLDDLDGIRPKASDVPFYSTVTGGLLDTEALD
AGYWFTNLRDPVRFDPALRAALAAGHRALIEISPHPILTMGMQEVVDDAGADAVALGTLR
RGEGGLRRFRLAVAEADAHGVAVDWSRAFAGTAPRRLDLPTYAFQHKRYWLDADGPRTAD
LPAAGLEDAGHPLLGAATDLAGSPALLLTGSVSLRTHPFLADHAVHDAVLFPGTAFLEMA
LQAADRAGFEGVEELILEAPLVMPADEPVRFQATVDEDGSLEIFSRPESAPARQPWTRHA
TGTAGDPPPSDTGDLAAWPPPGAEPVPLDGFYDRLAERGYRYGPAFRNLRAAWSRGDDVF
AEIALTGDETDAYALHPALLDAALHGTLRDAADGLRMPFSWQDVRLHAVGAATLRARLSR
TGPDAYGVTIADATGRLVLTVRSLALRAVERLSATGSGNLFRLDWPVVPPPDRAAPDART
WALIGSPDATAGVPDAAVHPDVAALRASSVPAPDVCVLVCPRGGVPESAESLHETVGHVL
SEVREWLDDERPGVLVVLTRGAVAVHPRDAVTDLAHAAVWGAVQCAQSEHQGRLVLLDGD
AASVASALGTGEPRLALRDGTLHVPRLVPSRPGDAPDERPWRLDLEPGDPDSLRIVPADE
APLGPGEIRVAVRAAAMNFRDVAVASGLVERHRVWPLMGFDGAGVVAETGPGVTGVAPGD
RVMGVFTGSTAFASTAVTDARLVVPVPDDWTFPEAATVPVAFLTAWHGLAELAAVRPGDA
VLVHAATGGVGLAAVQVARHLGAEVFATASPAKHPALRALGLDDAHIASSRSTAFEEHFR
AATGGRGVDVVLNCLTGDVLDASLRLLAPGGRFIELGRTDLRDPRDLPGITYAEFDLGLL
DPERQHALFGALRGLFDRGVLRALPFTSWDVRDARDAFRRMRRAGHIGKIVLTVPRAPDR
DGTVLVTGGTGTLGALTARHLVTAHGLRHLLLAGRRGPDAPGADALRAELTALGAQVTIA
ACDAADPAALRRLLDGIPAEHPLTAVVHTAGVVDDGVMTALTPERIDRVLRPKADAALNL
HRLTRRSDLAAFVLYSSVASVLSAGGQANYSAANAVLDALALHRGQHGLPATSLAWGLWE
RTSELTGALADTDRARLAQNGLLGLSDQDGLALLDAALSDGRPFFIGARLDAGAFAGRPE
DGVPPVLRRLVRPQRAKATARPAETGPAPLGERLAALPADDRVRELLGVVRAQAASVLGH
SRAEEIDAGRRFREMGFDSLMAVQLRNHMNRLTELKLPTTLVFDHPTPLELAREIDARLA
ARPGGRPSADDTAARVQRVLGDDRDLEEKVAFLREAVDARERRSGGDSADLAVRPVRLSE
GRATPRLFCLPSILAPAAPEQYGEFAGFFQGRRDVVALTLPGFSDGEPLPATADAFSRAA
ARTVLAEAADSPFVLLGHSSGAWLAHAVAEQCEKDGRRPAGLVLLDPADVNRNDPRDIAR
TADRLWARMDLLPLLDEANVSAMMRYAELFGAWTPGTLQCPVLALRAEEAMPGTSADWAH
AGRTERTPGDHVTMMTTRAAATAQAAETWAEDLT
>A0A1D2I3N7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. AVP053U2|TrEMBL
MRLAVRAAGLNFRDVLNALGMYPGEAGLLGAEAVGVVTGTGSEVTGLRPGDRVMGMVPGG
LGTDVLIDERFLVRVPDGWTDEQAASMPLVFLTAYYGLTELAGVRAGESVLVHAGAGGVW
VWTRITSRPRVIWVSRRSSGR
>A0A0N0NFW9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OV450|TrEMBL
MTTPTAPIAIVGMAVYLPGAPNLSSYWDSLSKGEDPISSVPAGCHAAGRDRRGIGPETAA
LQQHGEVPLELASVLTGRDGVSLGVAPSETALASQEELIAVHVAQAALADAGRLPLRHRI
GLIIGFSRPAQLRQPFASASHGLSTGGQPSTQAQAESHFPDPATTGSGLISFLTRQLDLQ
GHAFTVDAGCASPLVAVDQAVAALSSGRSDLMLAGGLLHAHLHGTNPAPAVLARPSPSQQ
SSPAQRDNNCPAVGEGTGLIVLKRLADAQRDRDRIYAVVRGCGVSGVGGYHTNDPSAWTK
AQSEAIRQAWHQAGLDPRAPGSLGLLEAHAASSPATDTAGLAALADVFCGSSPGSAQPVI
GSAKSMTDHATSAASITALIKTALAIHHGLFPPTLRCGGPPTAPATTRFHVISTAQPWAA
HPEARRGAVNILASTGTAAHLVLEQAPAAARSTKAPVLLSVSEPERILTLAAPTPGELAD
QLSADDSAVLSRGFPQQPPVGNTRLGITAPTPQRLALARKVVSQGQPWRGRSDIWFTPSP
LLGQAGGGKLAFVFPGLEGTFQPRLTDIAQYFKLPCPASATHTDVGDIGRHGIAVVSAGR
LLNTALRRMRIVPDAVAGHSIGEWTAMTVGGLYDSADVDAFIQSINPDALTVPGLAFAIL
GTSAVSAQNLIREHGDNSIVVSHDNAPNQAIICGPAGPIDALAQSLRARRIICRILPFQS
GFHTPMLEPFLRPIQQAVQALPLYPPTLSVWSATTARPFPADASEVRNLFIRHLLEPVRF
RPLIETMHTAGYRAFVQVGTGQLSSLIGDILGARDLPHLTITANSPRRDGLAQLRRVALA
LWVEGAPITPALTPTGSHTDLAGTSPVPSFTLSSPTAAPAIPAQRWLPSHGADSGAPARP
HLSGLARPPRHAVTSQSSPRQNSALEDVAGRFPAAAELSALLRETAETAEALVAAAISPP
PTAEDGRPAPPGARATPPAGAAATSPTSSQRHLDVSLENMPYLDDHCFFRQRPGWPEPAD
RWPVVPATTIVHHLMETARQTTPGVHPVAVHNTRFDRWVPAAPPQRLPVTATVTSPGRID
MSFGEHAHSTVELAPRYPRPPAPWSCDTAADRTPDITAAELYSKRWMFHGPAFQGITKLI
AVGDTHVRGIITTPTAPGALLDNVGQLIGYWIMATQVTRTIIFPTRIERIRFYGPSPAPG
TRLTCHISITSLTDSSLEANAQLLHNGTVWAEVTRWRNRRFHSHPDTTSADRFPEHNTLS
RPQTGGWALLHERWQDLASRELIMRNHLGSAERADYERQSPRSRRQWLLGRIAAKDAIRH
HLWRHGGDPIFPAEVRILNHDGGRPFALGVHDRRLPEIDISLAHRAEAAVAIVQPRTPGQ
GPPGIGIDIEEIGERSQATRAVALSDAERTLLDTLCCPPDGDSLAKWFTRFWAAKEAVAK
AEGTGLRGRPRDFTVIEAASDWLVVTATTANAERRYQVHCAAVSNPPDLPERHYIVAWTT
SPSRTPGESQ
>B2J538|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MNANQNNTDNRALLAKALLKLEKLQTKINTLENEKSEAIAIIGAGCRFPGKANNLEAFWQ
LLKDGVDTIAEIPQDRWDVDKFYDSDPNTPGKIYSRNACFLEQVDQFDASFFGISAREAV
MLDPQQRLLLEVAWETLECAGLSPDKLRDSQTGVFIGVMTQDYTQVVGSEPTSADIHTAT
GLGLCAGAGRLAYFLGLQGPTLTIETACSSSLVSVHLACQSLRLKECDLALAGGVNLILH
PYMSVIESRARMLAPDGRCKTFDAGANGMGRGEGCGAIALKRLSDAIADGDNILALIRGS
AVNQDGRSSALTVPNGVAQKKLIRQALANSNVEAADIDYIEAHGTGTSLGDPIEVEALGE
VFGNNHSQDHPLVIGSVKTNIGHQEGAAGIAGLLKVLLALQNEEIPPHLHFKKPNPRIAW
DKLPIKIPVDRTPWRRGKKSRIAGVSAFSLVGTNAHVVLEEAPVEEAEGQGSRGAEEQGR
SESKSSHLLTLSAKTPEALKELAERYQLHFNAHPQQSFADICFTANTGRSHFPYRLGVVA
SSASEAGDRLAAWVAGETNVAGISHKPSATSSAKAKIAFLFGGQGSQYLGMGRELYETEA
TFRATLDQCEEILHQQLNVSLFELLWGKSSYLLNEYIYIQPALFALEYALYQLWRSWGIQ
PDAVLGDNIGEYIAACVAGVFSLEDGLKLTIAHARFMEALPVNSAIAFTESTQIPQPVAI
STDKGSRSLSFSQPVETVYKPLAPQAESIAQTFNSSLVESLLADFETIARQINYQLPCIS
LIANRKGKVADGQIATPEYWLSQLGEPVQFETSVKTLQRLKYELFVEISPGSTLQEKAQQ
RSLKADVVWLSSLSLKDSERQTLLTSLAHLYTSGVKVDWSALECNHKRHKVILPTYPWQR
QHYWIETTEEPEISESSQIIETPILRLLNQGNTEELTQHLQKSATFTPEQIKLLPELLSI
LLNQHQQNLPEIAEQQSKILENLQKATNKNEILQLLTTYVIEQIAKVAKFDANKTIDSKQ
TLIDLSIDSMMLMEINSRIETDIQVVVSVEKFMENPTIIQIAEELIKQLIERGSISAVNS
>S5XVC5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Paracoccus aminophilus JCM 7686|TrEMBL
MSSSKAESTPLTRALDTIKKLKAQIDTQTGHQPIAIVGVGMRLPGNIETLDTLWDSLASG
ATLVGQMSPSRKAPFAEDWEGLPARGGYLDDVLAFDAEHFGISPREARALDPQHRLLLET
SLRAFEDAGIRPEMTEGQQVGVFVGITGQDYRDWQGEDKDAVWATGNGHCFAAGRVSYTL
GLTGQAVAVDTACSSSLVAVHQAMQAIRRGECDMALAGGVNLVLSPRSTKLVQETRSLSP
DGLCKAFDARANGFTRGEGAGIILLKPLDAALRDKDRIHAVIAGSALNQDGRSSGFTAPN
VLSQIALLKAAMEDAGLTPADLAMIEAHGTGTSLGDPIELEAIVHSIARGNDGRQLHIGA
VKANIGHLESAAGIAGILKAVACLRHGAVPPIAQFGTLNPRIDLEGTQVSFPTTVEPFSD
GRRVIGISSFGMSGTNAHVLVGAHDAGEVQPDAGADGLFLSARSATALAELARLYADRLA
EVAAEDYPAFAWTASHGRTRHEIGAFVKASTPAEARAALLALAEGRADARIVTGPEAEDL
RDADPAPRRVFDLPGYPLSRSPCAPDHALAAIAAFAQPKDARVAQMPLMATRWVPLELTA
SDEASGDGFAVVGEDTALLEGLRDAAVSVVALDEAPAWEALWQAQAAAGVKTAVLALRAE
ALPETADTGDPAAAGAAFCAKLNAAVQSAARSGIRVFAVTRGTQMQPEAVSHHALVNGLA
PVLGLECPAGWGGTIDLAVDALGSDHLALARFVTSAGHEDRIAIRDGQLYGARLVPEEIA
QSPLPVSDGVHVLTGGLGSIGRTVAADLLACGAKSLLLLGRTAEAALSKGAAQALADLRT
SGAEIRYAALDCDDGAAVAALIGGLAASGQRIAGIVHAAGALAPAALDGLDADGFAAALR
GKYSGAWWLHQATRDMDLDYFATLSSVTAVWGTEGFGAYGAANGGLETISVARRAAGLPV
ACVAYGPWALDDSMADEAARAGFARLGVHAVEAAPGVAAINAALPEGAVSVVACALDAKR
FVKVMGAHRPRALFNALLADQDTALPSVEPEVVAVNAAPFLEELAARPAATRPRAIAQKL
REIVGATLGHADPSAIREDKGFFDLGLDSIMAVDMSALLAETFGLKVQVSEIFDNPTISS
LAAHLQAQMAGQPLPQAPAAPAAVPALRVQADEPHADTTRASKDHDGPVSDTTVPDAEPI
AIIGMAGRFPGADDLDAYWTLLATGQDAVGRVPEDRFDIGALFNTDPRSTGTISSDQGGF
LKNIRAFDAEFFNLPRREAESMDPQQRLLLETAWHAIENAGISAQALAGTKTGVFVGATN
VDYARVMEKGGLPGLDAYYGTGTSLNTLPGRIAYVLGTHGPSLAVDTACSSSLVAVHLAV
NSLRNGESDQALVGGVNIITAPDCSVAVSRAHMLSPVGRCKAFSAEADGFVRAEGCGVLM
LKRLSDAQADGDRVLALIRGSAVGHDGASSGLTVPSGKAQEMVIRDALENAQLAPAEVSY
LEAHGTGTSLGDPIEIAAAWSVLKTGRAADRPLALGSVKSNIGHAESAAGMAGIIKTVLA
MRHRQLPGNLNSTPPNPHIRWDDMAVAVVDRLTDWTAERLIAGVSGFGFSGTNAHVLLEE
APELAAPTIEAIGPYLLPVSADQAEALPRVAAVWAERLEQASDADLAGLALTAGTGRAHL
PARRAVLGDTRAALVEALRKVSARKPASGTPRVAFLFSGQGSQYFGMGLDLYETEPVFRA
VIDDCDKILSPLLGQSLLQVMLYGADKTLLNQTRYTQPALVALELALAALWESWGVSPCI
VMGHSVGEVAAAIHAGVIDRRSGLELIARRASLMQDMKPGAMLAVVATPETVTGLLEGTG
LDVAAINGPEAVVVAGPQDRVDAFAETLKKMGIEARALVVSHAFHSRMMQPMIAEFREQV
DQFDFHEARTPIIANLHGRLADSATYSAQYWCDHVLAPVRFHEGAQAMLAEEVDICLEVG
PDRTLVSLMRAAGLMPEGGMTNSLRRGLAERPTLLGAVAHLYDRGQSFDWAKVQGALQAR
RGDGPLYPFAKTEYWTQITPQPALAVRGVETRRHWGAELLSPALPGRVFQFERDSNFPAY
LGDHRLYGTVVTPVASHLATILSALGRDGTPVAIEDLVCPRALVILDGERYDAQIITGAG
EKPQLSVQSLIDAETGTWQTHAMCRLSDNGATFAPMLDREAFIAGAERHISGAEFYAYFR
TLGYTLGSSFRWIADVWIDGEEALIRYAQPELPDDPAAYEIYPGLIDSCFQSIAGFMVDD
HAEEAPSLAIPFAARRLAFAGRPRGAADLWGHVRIKSADPLPNGRLRVETADLAMFHADG
QPVFSADTFRVRHAPRAVLEHGLRKPPKHAYEPVFVAPDSRPARDESVRELRLLTDGVPL
LNDLVPALEARGVTTRLDQLPEASDPATEGLRIVDARFASVDGVAAEDVEHAVALLAETL
RNVPHAVPYILLVDGSPEASPLRAALWGMLSALEAEQSDRRLVRVKIGADAAIETLAETV
LAVPQENRLSVGSDGLRVERLLPAAVTLPEGLPQGAALITGGLGALGLSTAEMLANAGAA
GIVLMARRAPDAIAQEVINRIAAQGIPLRIVQGDVTNALDVKAAIEAARSFGKLGSVFHL
AGANDDMAFDSIDRDSYARVFHAKTRGAQVLARALHDDAEVRLVFFSSVSSVLGSAGQVS
YAAANGYLEGLAEALRAGGKQACAVAWGPWVPEAKGGMAASDVVLRSAARYGVRPLNDAE
AAELVAIAASGQSGRLVAVAADFARYRAELGAQSRASFLSALDAGEVTTPRKTEVTEAAR
GWLRDLALAEPAEDRIDSLREALARLVCANLGDESPIDHDTGFVELGLDSIMAIDLRAQL
NHALDHDLPATVAIEYPTVAQLAEFIAETGLGQIEPAPAAALAQTTTPIKTQTATPTPSQ
PDTENLTDRSMSDLLAAVQDELNWTEGKHK
>A0A378ZKG3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Paenibacillus thiaminolyticus|TrEMBL
MDKGQDKRYKDICNWFVQQISALKQISQHEIKAEFPFSRYGLDSKELVSLSGELESFVKR
SVDPTLFWDYPSIQAVARHFAFGGENGHAARDDCGAEQEDAIAVIGMGCRFPKSRSIDEY
WHHLRSGENCITEMPGLRSSRFAQDGMHRAGIVEEIDLFDNEAFHLSPREAEQMDPQQRM
LLEVVWEALEDAGLTNEAMNGSRTGVFVGISSNDYGCGKLSDYERSGIYTVTGNSNCIAA
NRISYIWNLRGPSMAVDTACSSSLVAVHLACQSLKTGETNMAIAGGVNVILNPAISKAFR
EAGMLSADGRCKTFDSRADGYVRGEGAGAVILKPLAAALRDRDRIYAVIRGSAINQDGLS
NGLTAPNGQAQEEVLQDAYRIAGLSGEEIDYIEAHGTGTALGDPIEVQAIGRVLSRNRSA
ASKCYIGSVKTNIGHLEAAAGIAGFIKTVLCLHYREWVPNLNLEEINPYIPLRDLPLQIV
RDPVSWSSGSRPSVAGVSSFGFGGTNAHVVLQQYATSLMPPAQTSQQAPPSLHILPLSAN
SHGSLTRLAADMQRYLQERADASLDDICYTAQQRRTHRAWRAAVLGSNREELALGLERLT
ATCASADPSNLVFVFSGQGNQWNGMGLQYLSGDNAFTRTFLECDAIWSKYAGWSLWDELH
RGADDAWADRTDAAQPLVFAVQASLLALWRSWGIEPKAVIGHSLGEISAHYAAGVLTLED
AMRIVYWRGTLMQSTKGQGAMVSIRMPLADIEQRLGEYPGVGISAVNGPSSVVVAGEAHE
VERLLRNLPDTVKTHFLSSSFAFHSHLMEPLCDRLQTELGPVRHRLARLRIYSTVTGRME
NGLRLGAEHWSDNMRKPVRFADALHAAMLDGYDAFVELGPHPVLTQHVEECGQDGEVKLA
AFSMRRGDDGACMPEAAARLYRYGADLDWNAVGSRGQCIAIPTYPWEKRRLWIDDPEALE
RGTIGAVPESQTDRARESSRNASSVQHILQAVRDRVETLPLLEEHLQGMFASVLKIIPAS
DLSLDRPLVMLGMDSIMALQLKHAIEQQFQVSLPIVQLLEGITTRQAASKLHGILLDARD
RQSNEERSRIDDLLNSGDMERDLGELSDEDMERLLLLLTQEKGS
>A0A5C5ZZJ9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Rhodopirellula pilleata|TrEMBL
MVGSYVMAECLRNGLNLVVLARDRGKQSASQRVEQILKRFEESWMTNLPRPQVYHCDLNR
HSLGLSADAIGSINAQCGRILHSAASLSFAPANQSKENEPYRTNVEGTQRVLDFCCEHEI
RNFHHVSTAYVCGKRSGVVRENESDVGQSHANDYERSKTIAEARLQDARRLGHLDALTIL
RPSIVIDRTGLSPISADRTIYGAFSMYQMLASRFGLPERGQWFNNLGFDGAECKNIVDVD
WIAKAVRVILTTPRYHDSTYHLTTRSGTSVVDLDTAFHIATEQWLARPSRVARTSPAKLT
AISGQQQAELDRMAAPFVQTFLPYFRDDPTFARDQIDRVISGTDLEPPPEIGTDELLEMV
RHWSAFIPEKPDVSQNQPEHQVESDPLATDPDEVVVCGYEVRLPGGVENVHDFEEMLWEG
RSGIAPMPPDRLDRSLYFDPTKGVPGKTYSQLGGCVTPSPLNHEREREIEMLGHFDLTHR
QFCQVAMEAVGAAFGTHRIDQVSGIDPSRAGILVGHSGGTEMGGALAMHTLAPATAECLF
ETDLNAAADDSDLRTLQTELTTAIQRGRPGWKSDGSPHFNAYSVASLAGSLTGFRGRREV
IDAACSSSLLALHHAVTAMQADRMDIALVGGATFNNVDNLALFSQSGACSDEGCYPFDRR
ASGLISSEGYVAIVLVRRSLAERLGLPICATVVGVGVASDGKGKGLWAPRSEGQQLAIRR
ASAAAEVPEPEGNTVLDLDYLECHATSTQVGDATELESLSALLRSNPDLVSDATLASRLP
IGSAKSNLGHLLEAAGLVGLVKCLIAMKKGELPPSIQFDYPNESFEWENAPIEVVDSVRV
WPQRNSKPTRVAGVNAFGIGGLNAHAIIRQSSPTRRSRSIRVAPSSPTRDRESEPIAIVG
RGVILPGAENIRALTDLLQSDQTQISDPPQGRWPMRSDRSGWIGVNRSCPGSLPHCRGGY
ITDFRFDAQSYRIPPKTIRFANPAQLMLIQATAQALQESGVTDDLMKGKWAIDRQRIGVV
IGTIFGGEFSNALQIGLRLPEIKQHVEAILRRRSEPGIPIDEVTQQLGGILMDRYPALFD
ETGGFTASTLASRIARTFDLMGGACAIDADEASSGLAILTAAEQLRGGHVDAVLCGMAHR
SMDLVAFEQLYRKNQLVESGCQKDLPDDGSRIFPGEGVAIMMLQRLSDATSQGRPVLGII
DGETESWATDVSEARKADSRQSKSIGLASASKIVSQIGHFGGGQGIVRTIAATIAFEQNP
SSPSDYAITETAQDGFQVRYQIAPPPMPVSMNQSSSRSQAGSDEVRCQDAPSVRLVASRP
ISESAAARSLFRYRLQSRSLDQIEHDLRHLAADPNEMVGSAVNQYFESNYPTIQAAIVGR
STEEVSQIAQALLDGPVTRRQTSALAKQCGWLRLNAENHSQRQNGDRVAWLFPGQGSQYA
AIPSLLDSNVDAVAASRAHEFLGDIDSRLRARGLEPVGSRIDDPRRQLGRDIWWTQLWVL
AIGATMADSLSRRGHRPDVVLGHSFGECTAAWAAGAMTIDQAIEFAKCRSDAVIMTRQVD
GELLSVRGEPSAVQAVLTRQSSSAVISHHNSPTNTVIAGSRAEIAKAKASLADAGLASVV
ISVPAAFHTPQMKPAQDLLRARYGGQHLMPPRCGFLSAVSNRYLAEPTELMDNLIDQLTK
PVCFHGALERIVAEGCGLLIEVGPDNVLTRLARATVGGRAICLSADDRQQDYHSQHALID
MACEAFGNQPHQHASDRSETPTDSAILRTMSSKPHRNGDGSSDLVMRSDTSEGNHRKRFD
VVDVTRQRRRSVAANQEAKAGPKSKIGSAEPGTPMIGSTIDLQTHGPAEPIAAVDLQAAR
SFLFDLVVDLTGYDPEIIEFDADLEAELGVDSIKKAQLIGEMVQWADIAIDIHAMPLAKF
ETLNDIVGLLAEGPILAKTTSNHQSALDGLTDDVDGAFFHESPSDPPVRQAAPDLESLHR
LMIDLVVDQTGYDESIIDMDADMEGELGIDSIKKAQLLGELEQQYQLQSLRDSNLSLADF
STLGSIRDFVWKQLTGGPDETSNRTLQKKNESDSAVATVSASIPVPSAGTHRFEIRTHLA
PRLGGVAEQPRWYGPAVVVGRNVIADAILARWRRDPESSIHPIHAIDSSLSADELETELD
ALWSGEVSPHLFITTPHDAESGWSVDDPDAWKTRRQSGLLNPFRVCQRWMQGRIDLNAMP
QSSLVTIVRAGGSFGFRPLGLSNQGIDSADSIAAESGGLAGLTKAMLIEAWMRGHRDTPM
LVIDPLTGSSPDEVVDGVWRELAAPSYDEEVIIAGTTRMTTIASYAPLHGNDSSSATQSP
SITPKGAWVIAGGGRGITALTSMELAARYGLKLHLLGTAPVPQIDESMRRAAATDRGELR
RRVMAQIQSKGGNPVTTWQKLEKAIEIDQTLQACHERSIDAIYHSVDVADAEAVKECLRR
IREVDGPIRGVIQGAGAGQDARFDRKRPDKVEKCFRAKVDGCVSLAAATIDDPLEWFIGF
GSISGRFGANGHTDYSAANDMLAKLITQLKRQRPQTRCVTFHWHAWGDIGMATKPEAKLA
LDMIGMEFMPAREGLQHFLDELEHGGDLTEVLITDRRYVRKFFPEGEWVDRDQAATATFP
MLDPEGHRQQTSPSSTSYAITLNPTTDRFLKEHLVHGRPTLPFVIAIEMLAEAARARHAE
KTGEFLQVIACHDVRAHQSLKCLTDDAFAVELVPAGDESDRWTLVSDLRRRDGRLVQAAR
PHFSATIELGREADTDRWTREDLFEGHNFTVQPVVYQPNEAPVYHGPQLQCLREIGFDLS
AGDDRVGIAVGLVVAPSPAHLAGEQRPLRGWSILPAAVDAVLYAAGCLAYRIGDRPNLPI
SFERIQVGRLPRPGEVLRVVVELSEMNQQGAILSAKLAGQNRDRIVQLDGYQIGWLG
>A0A1R4LF44|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Vibrio ruber DSM 16370|TrEMBL
MQWKSEMRQCVQDLVTCHPEERMNDYALIFLDHTGQRRELLTYIDLKTRCLAAARQMRHR
TNPGDVVLIAIEDQCQFVIGFFACLLAGCVPAPLPAFRHQNDKQTIGRIRAIVQAGDATI
LLLPVEQQALAQMCFADLPLNILCVTSLIAPEADSDSSEPLVLPEVSPQDIAYIQYTSGS
TSQPKGVCLTHTQVLANLDAMGGTFQRQERVRMVGWLPLHHDMGLVGHLFTVLNESGQGY
FLPPASFLAAPDVWLAAVHRYRGNLAAVPAFAIDDCLRRVTTPDPQWDLSCLKYLYVGSE
TVDVGQLTAFVERFQAVGIQASAIYPVYGLAEATLLVAGGMLSLAALEPYIMDKSAGSVQ
WRLTPYPLSALQQDIGICDPASGTELPPGQEGEIIVRSPSIFSGYYQSDSGQLPGGVTAL
HTGDLGLLVNGCLYITGRLKETVILRGVSYHAEDLEMVAKFDHDSLRSDDKTACVGHVVN
GHEQLVIFQEIQRHTPRHQYPAIVQTMQANLSDNFGIQAQAIHLIAAGLMPKTPNHKLAR
NRCMALYLSGELKTLYSSPEVPVGKVSASSATSEADDAVVIVGMACRFPGGVETLEQFWQ
MLCEGRDGITKVPATRWDNSIFFDPQVAVPGKMNTRWAGLTDHIDQFDPALFGISPYEAA
EVDPQQRMLLETSWRLLEHAGVTKADLKHSDTGVFIGIANNDYLYLKIKLSETLEGFNAY
SGLGNANSIAANRLSYFYDLKGPSVAIDTACSSSLTAFNYGLKAIRDGECEQAIVGGVNA
IISPGTTVTLSQFGMMSPKGRCKAFDASADGYVRAEGCGLVMLKRRSAAMRDGDRILAEV
KGCVAAQDGQSAGMTFPNGTAQHRLIRKTLQQAGLTGSEVRFIEAHGTGTPTGDPVEMEQ
LVDLYGGPGGAPCYVGSVKANIGHLESAAGIAGVIKVVLMLNRHIIPPQVHFSQLNPRIH
LEHSRLMIPVEARPWEDRHKVAAVSSFGFGGSLAHAILAAPEPVTGVQTAETGEMSFFAD
YKRASRDGAFYEDICHEGTEQLFVLSHHSAGGLLNQARCWSEFLETPPLISLADLTTTQA
QCRTHLRYRKAFVADSHSGLQAQLAQFVSRQSKVTVPADMSARVCFLFSGQGGQYLHMGE
TLYQTLTVFRQAFDRCAKAWAEASLPGQTLLGEHQDRHAQSLSLQTLAFDTPADNVVAQC
YQPVVLFAIQYALGIAWQACGVMPYRLLGHSLGEYTAACLAGCFSPETGVRLLKKRAELV
VKLAAPGTMVTLFAGKAEVAAALGDAPVQIAVVNSPGKTVIAGPEAAVRQVAQQFSDRGV
QVQPLPVPYAYHCHLLDPVLAAFNAYASQFTFLPPVKYWISSTTATRMTEAPTAAHWVRH
MRETVLFSDAVGHLAQDNVSNFLEIGPGTGTLVAVRECLTQPDLVLLRSLSPPKGGKTER
AHFLESAGRLYEQGVDLIWQSLLAGEQKPDQIPGLVFDHQRYWLKGLEPENIAAFAGPIY
GRHLPISSDASASAGRPVQPARYDLVWVKRQPVPHPEDVVDLRTRLSWLLVGPDSAILQS
LSAQIRARGHQVFWLSTDGADRHACDACLLPQAETADAFVTLNHILTSRSRADIEAWKVV
YLSDEDTLIAPDQLALPEMDQALRTSLGGLIVLLKALRQVAITPPVWVVTRMSQQLMSDA
AEQVNLSAAPIWGFAKTLYLEHPEWRGGMIDLDAGTSADTNAAGLMAKILHPGSEHCVVF
RQGDQYVEQLAPVSAPSQPSETVTFRDDGVFVITGGLGGLGLKTAQWVIDKGARHLILIS
RQSLPPEEQWVTLTDRDPVLTQVQQLQVLRAQQVIVEVVSLDVRNPGALTGLVQSLAERD
IPVRGLIHAAGVNWFDKIIDLDPEAFFDTLQTKIAATWQLHQLSLSMDLDCFLLYSSVSA
LWGSVNLSHYTAANFFLDAVSLYRQGIGLPALSLDWGPWAEVGMSAKPEEAQILGKMGFT
LMPPTDALHVMEEAMVTGRALSLIGQIDWQQYQSFIDFTLQPSLFEQVVGVHHLADAAVT
QEHLQPIVGAGPAEARAQIKQIVVMELRSVMLIESVDDIPGDQRFNFLGMDSLMAILFAT
KLEQYFQVKLPNTLAYNYPHINAVTDYLFELVYQTKHPQTAMTEDTRDDVPNEATMKPQA
APAPAPTLPLPIAAVTQAQGKWFRVFKPITPDTQIVLYCFPYTGSGALVYQAWNAELPPG
VALIGVQPPGKDERSEEPPYTDMHALIDDLMAHFDPPADLPFAFYGHSLGALMAFESCLA
LAQDGRMLPVHMILSGCNAPAVRDSEHIHGLPDDQFIDAVLEKYEGADRHSTRRLILART
ITLLRADIKLLETYQPQDSTVGVPLQIIAGLDDPILSPKRVRQWVNFSTGDFELCYLPGG
HRLVHEQQAPLLALIAHTLRDYLADKSSNPQENIDIHMVDISSVAVQPHLNGGK
>A0A1Y5P998|6-deoxyerythronolide-B synthase|EC 2.3.1.94|uncultured Mycobacterium sp|TrEMBL
MSESQTPETPDTPDSVNEAPYREEASPRTDMTVQEMREWLRNWVANATGQGPDAIDESTP
MVELGLSSRDAVAMASDIEDLTGVTLTATVAFRHPTIESLATVIVEGEPEVEFDGDGEDW
SRAAGVEDIAIVGVSTRFPGDMNTPDEMWAALLEGRSGISDLPEGRWSEFLAEPRIADRV
AKAATRGGYLTDIKGFDAEFFALSKMEADNMDPQQRMALELTWEALENARIPASSLRGRD
VAVYIGSSNNDYQFLAVADPTTAHPYAITGTTSSIIANRVSYFFDFRGPSVAVDTACSSS
LVAAHHGVQALRSGEADVAMVGGVNAMITPLVTIGFDEVGGVLAPDGLIKSFSADANGYS
RSEGGGMLVLKRLSDARRDGDEILAVIAGSAINHDGRSNGMLAPNPDAQEDVLRKAYKNA
GINPRSVDYIEAHGTGTILGDPIEADALGRVIGRGRPADQPALLGAVKSNVGHLESAAGA
ASLAKVALSLSRNKVPPSINYAGPNPYIDFEGIHMRVAERVTDWPRYSGHAIAGVSGFGF
GGANAHLVLREVLPADLVEPQAESESVEGATTSDADAVYVGGVRMDEYGEFIDDEPLGRR
ASDSDDDAADNEYAAADAYADDAEPELPGLTDEALELIEAARAEWEATEDKPVPVVPLAV
SAFLTSRKRATAAELADWVDSPEGRATSLEAIGRSLSRRNHGRSRAVVLAHDHDEAVKGL
RAIADGKQSPLVYSADGPVTNGPVWVLAGFGAQHRKMGKSLYLRDEVFAEWINKVDAHIQ
DERGYSVVELILDDAIDYTNETCEYPIEVVQTVIFAIQIALGELLKHHGAKPAAVVGQSL
GEAAAAYFSGGLSLADATRAICARAHLMGEGEAMLFGEYIRLMALVEYSAEEIKTVFSDF
PGLEVCVYAAPTQTVIGGPPEQVDAIIARAESEGKFARKLQTKGASHTQQMDPLLGELAA
ELQGIEPHPLQLGYFSTVHEGSYIRPGGEPIHDVDYWKKGLRHSVYFTQGIRNAVDSGYT
TFLELAPNPVALMQVGLTTAAAGLHDGQLIATLARKQDEIESMVAAMAQLYVYGHDLDLR
TLFTPASGPADYAHIPPTRFRRKPHWLDAQFTGDSSVMMPGNHVATPDGRHVWEYSPKGQ
TDLAALVKSAAVQVLPDAKLTASEQRAVPGEGARLVTTLTRHPGGASVQVHARINESFTL
VYDAIATRGGAASALPAAVATGVAVTSPAGEVAAEPDDDADILQDNLTAGAGLAAGFAKW
SADSTETVHDRLAAIVGGAMGYEPEDLPWEVPLIELGLDSLMAVRIKNRVEYDFDLPPIQ
LTAVRDANLFAVETLIQYAIEHRDEVEELAETQKGKTAEEIAAEQAELMGGATTVAELEA
KLAEAGHPIATESEPKIPPPPTDPAGPGFGASEATGEVKSTAAAAAAKVLTQEAVAEALG
ADVPPRDAAERVTFATWAIVTGKSPGGIFNALPALDDATATKMAGRLSERAEGVISVDDV
KSAKTIEELATTVRSELEEGVVDGFVRILRAPSENTADNPKTPVFVFHPAGGSTVVYEPL
MKRLPADTPIYGLERVEGSIEERAAEYVPKLMEINGTGPYILTGWSLGGALAYACAVGLK
RNGCDVRFVGLIDTVRAGEDVPQTKEEIRARWDRYALFASRTFNVEIPEIPYEQLEELDD
EGQVRFVLDAVKEAGVDIPGGIIEHQRTSYLDNRALDTANIEPYDGHVALYMADRYHDDA
IMFEPRYAVRQPDGGWGQFAADLEVVPIGGEHIQAIDEPYIAKVGAHMSEAINRIDAEEN
ESK
>K9PIC3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Calothrix sp. PCC 7507|TrEMBL
MEIAHNGLEIAIIGIASRFPGSNTVDGFWQNLIAGLELISVFPDTQTIKAGGILEDVDLF
DASFFEINPRDAETMDPQHRLFLECAWSALENAGYDSQRETRPIGVYAGIGMSTYLLYNL
YPHQELMASRGLLQTMTGTEKDHVPTRVSYKLNLKGPSLSVQTACSSSLVAVHLACQGLL
NGECDMALASGVAVKVPQNDLTLSPTELVSPNGHCRAFDAQANGTIGGNGLGVVVLKRLE
DAIADRDHVYAVIKGSAINNDGDAKIGYTAPSQEGQARVIRAAQMMAEVEPDTITYIEAH
GTGTALGDPIEMAALTQAFRAGTNKQGYCAIGSVKTNIGHLDAAAGIAGLIKTVLALHHK
VLPPSLNFETPNPQIDFEHSPFYVNTQLREWQTNDIPRRAGVSSFGFGGTNAHVILEEAI
QVKSQKFTLSAVEVSKVKREYLLLCLSAKTDSVLETTTKNLAQYLEQNPHLNLADVAYTL
QVGRREFAHRRVVVAANLEQAVTALQSGDAQASLTESSVHEVTPQEYRSIIFMFPGQGAQ
HVNMARELYQHETIFQQECDRCFALLKPHLDIDLQQVLYPNEEDIQTATQQLQQTAITQP
ALFVIEYALAKLWMSWGIVPQAMIGHSVGEYVAATLAGVFSLEDALALVATRGKLMQKQP
PGTMLAVGLSAEAVQSFLGEKLSLAASNSPSLSVISGAVDAVEALEKQLSAKKIDYRRLH
TSHAFHSQMMDGIIEPFTAQLQHLNLNPPQIKLISNVTGTWMTAEEATDPTYWGRHLRQS
VQFSLGIAELLKDAQAIFLEVGPGQTLSTLTKQQTSERIVISSLPHPKEQKSDLEFLLKA
LGRLWLAGIQVDWEGFYADEKPGRLPLPTYPFERQRYWIDPPEASPGTLDKKPDIADWFY
VPSWQRAILPLPKMDEQKRCWLVFVDESGLGSSMVERLEQLGHSVIQVKIGGEFSRNSDR
IYTINPQQQKHYEQLLAEILVSESISYIAHLWSISFTEQDMGFYSLLYLAQAIGNQNVTN
SIHIGVVSSNIQDVTGTEIIYPEKATLLGACKVIPQEYANITCCSIDVVPASFLENQIIT
EIAAQSTDTVVAYRGNYRWLPTYTAVRLEKAQKPIPLQPKGVYLITGGLGGIGLAIAQYL
AETVQAKLVLVSRSHLPSKDEWKQCLKDHNDQDATTSKIRQVQVLENLGAEVLVLSADVT
NAAQMQMVAERSQQVFGHIQGIFHAAGVAGGGIIQLKTPEMAANVMAPKVTGTLVLEETF
KDNNLDFLVLFSSLSSIVGGAGQIDYCAANIFLDVFASYKASKTKTFTTSINWDAWQEIG
MGVKTTEIPDVLQQQRLETLRTGISSKDGLDSLSRILQSGLNRVVVSTKDLQTVLKQKHD
GIPHEELNPQKIQNSPSAHERYLAPRNEIEQQIAQIWQEQLGIEVVGVNDNFFELGGHSL
LAVRLVSRLREIYQVELSLRTLLEAPTIAEVANAITENLLQQPELEDMNQMLAEIESLSL
EEVQEQLSNI
>D5P4N3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium parascrofulaceum ATCC BAA-614|TrEMBL
PGSAELIAELEEAGARVRAVACDAADREALASVIAAIPAEHPLTGVIHAAGVLDDAVVTS
LTPERVDAVLRAKVDAAWNLHELTRDLDLSLFVMFSSMAGLVGSSGQANYAAANSFLDGL
AAHRRAHGLPGISLAWGLWDQASAMTGGLDAADLARLGRDGILALSSDEAMELFDTALAV
DEPLMAPARIDLNALRAHAAAVPPMFADLVNAPARRQVDDSLAAAKSKSALAHRLHGLPE
TEQHAVLLDLVRSHIATVLGNTTPEAVDPDKAFQDLGFDSLTAVEMRNRLKTATGLALSP
TLIFDYPTPNGLAGYIRGELAGVPQEVAPAPVARAVGDDPIVIVGMSCRYPGGVDSPDDL
WQMLVERRDVLSEFPTDRGWDLAGIYNPDPDVPGTCYTRTGGFVDGVADFDPAFFGIAPS
EALSMDPQQRMFLELSWEALERAGIEPGALRGSATGVFAGVYTQGYGMGAAPAAEGFRLT
GQSSSVASGRVSYALGLEGPAVSVDTACSSSLVALHMAAQSLRSGECDLALAGGVTVNAT
PDIFVEFSRMRGLSADGRCKAYAGAADGTGFSEGGGMLVVERLSDAQRLGHPVLAVVRGS
AINQDGASNGLTAPNGPSQQRVVRAALANAGLAAADVDAVEGHGTGTTLGDPIEAQALLA
TYGQDRTEPLLLGSIKSNMGHTQAAAGVAGVIKMVLAMRHATLPATLHVDEPSPHVDWSV
GSVALLTEPRPWQPNRPRRAGVSSFGISGTNAHVIIESAPAQPAPAPERTKLPVIPWVVS
AKSLSALSSQAHRLAGHLRRRDELDGADVAWSLAGRSHFDHRAVVVGADRDQLLAGLDEL
ATGGAGSVVQGTAVSGGKTVFVFPGQGAQILGMGMGLHAAYPAFAVAFDTVVAELDRHLL
RPLREVMWGHDESLLNTTEFAQPALFAVEVALFRLLESWGIHPDLVLGHSIGELSAAHVA
GVLSLENAAVLVAARGRFMQALPEGGAMFAVQATEEEVRPLLERSEQVGIAAVNGPASVV
ISGAEDEVSAIADRLRADGRRVHRLAVSHAFHSPLMDPMIDEFGTVAAGLALGKPTIPIV
SNLTGQPAGDDFASPAYWKRHIREAVRFADSVRFAHSAGATRFLEVGPSGGLTASIEESL
ADAPIVTMSALRKDRPEPVILVNAVAQGFVAGMDVDWRRAIGQANFVELPTYAFERRRFW
LAGDGTTVDAAGLGLAPGEHALLGAVVELPASGGVVLTGRLSPGTQGWLADHAVGGVVLF
PGAGFVELAIRAGDEVGCGVVDELNLAAPLVLPATGSVAVQVVVGGADEAGARAVSVFSR
TDAGSGWSLHAEGVLRAGAVQPGADLSAWPPIGATPVDVGDGYERLADRGYGYGPAFRGL
TSMWRRGDEVFAEVALPADAGVSGVGFGVHPVMLDAALHAVILTSDGDELPEGSMLVPFS
WQRISLHAAGATAVRARIVPVSDSAVSIELADGLGLPVLSVGSMVARPVTDQQLLAAVSH
SGPDRLFEVIWSAQRSTSVQPVTVSHWGATALDDAEAQPAAVVFESAPVADDVVADVYAA
TRAVLPVLQSWLAREGSGTLVVATRGAMALPGEDVTDLAGAAVWGLVRSAQTEHPGRIVL
VDTDGRLDDESVAAALAVGEPQVLVRGSTVYTARVHGTRAVAGLLVPPGDGPWRLGMSSS
GTFENLRMERIPDADAPLGPGQVRVAVSALAANFRDVMIALGLYPDPDAVMGIEASGVVI
ETAAGGGRFAVGDRVMGLFPDGTGTIARTDERLLAKMPAGWSPTAAATTTVVFATAYYAL
VDLAAAKRGQRVLVHAAAGGVGMAAVQLARHLGLEVFATASRGKWDTLRAMGFDDDHISD
SRSLDFEEKFRSATGGRGVDLVLDSLSGDFVDASLRLVAPGGAFLEMGKTDMREPDAVAR
EHPGVRYRAFDLFEAGPDRIARILDELAAMFADDVLRPLPVTRFDVRRAPAALRYLSQAR
HVGKVVMTMPDAWAAGTVLITGATGMAGSALARHVVNRHDARNLVLVSRRGLDAPGAAEL
VTELSAAGAQVQVVACDAADREALAKVIADIPVHRPLSGVIHAAGVLDDAVISSLTPERV
ASVLRAKVDAAWNLHELTRDLDVSAFVMFSSMAGLAGASGQANYAAANSFLDGLAVHRRM
RGLPAMSLAWGLWDQASAMTGALGAADRARFGRDGIVAMSSDEALELMDTALIVDEPFLL
PAHIDLAALRVKFDGGTLPPMFVDLINAPTRRQVDDSLAAAKSKSALLQRLEGLPEDEQQ
AVLLDLVRANIATVLGNSSPESIDPDRAFQELGFDSLTAVEMRNRLKSATGLALSPTLIF
DYPNSAALAGYMHRELVGAAEQQSPAAAPGEAEIQRAVGSIPVKRLRQAGVLELLLALAN
EADGSRADGQSPAAAATSEKDIADMDLEDLLNAALMDDDE
>A0A3N6FHP3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-17|TrEMBL
MTAFLELGPDGVLSAMAQDCLTDTTVDPEKFGFVPALRKDRDEPQALLTALAELHVRGTA
VDWTAYHAGTGARRVDLPTYAFQRQRYWPKPGGPVAPETDAVSSMDARFWAAVEQEDLSG
LVEGAGLTADQPLGEVLPLLSSWRRQSREQSTVDAWRYRVAWKAVADDTGAPVSGTWLVV
AADEHLGHPVVAGIEAHGAAVARLSVDSGTRDRTGLAEQLAGAGEAAGPEGIAGVVSLLA
LGQDPMAATLDLVQALGDAGVRAPLWCLTRGAVNTGRSDAAPEPAQAQLWGLGRVAGLEQ
PQSWGGLIDLPAKPDERAVDRVLALIGGGSGQDQAAVRPAGVFVPRLLRASANTTSSEWA
PRGTVLVTDATTPFGSYVARWLAGTEADRVVLMTPEGQEPAEAAVTALGERAVVAHCDVT
DRAALDALVRRLADEGGPVRAVVHTVGGNHLAPLDTIRMEDADARLAAKVVGAAHLDAVL
ADTELDAFVLFSTIAGVWGGGGQGLYAAAGAYLDALALNRRARGLAATSVAWGPWADGDT
TEGAVRDSEAGQAEEAELLRRRGLPPMAPELALTALRQAVADADPLLTVADVDWARFAPS
FTALRPSALLAELPEAADALAGDAEPVGVDDDVADELRQRLEAMSEPERDAELVRLVRTH
AAAVLGHPVDEVGADRVFRELGFDSLTAVELRNRLTRATGLRLPAGLAFDHPTAAAAAVF
LHTELRFDSDAPDASGASLLAELDKLEAATSGKEPDNLTRTRVTMRLQAFLAKWSDGRAE
TEQADVSEKLESASDDEIFDFINQELGRSN
>A0A3N6E211|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI91-18|TrEMBL
MDWDAVFAGTGAQRVDLPTYAFQRDRYWIEVPVSPVGDVASAGLGSAEHPLLGAAVELPD
SEGFLFTGRLSLQSHPWLADHRAAGAVMLPGTAFVELALHAAQRAGTAFVDELTLEAPLV
LPEQGALQLRLSVAAPDEAGRRVVLVHSRPETGNGEGVRSQDVPWTRHAGGVLGAGDAVA
SPPVPAPEVWPPAGAEPLDVADLYEQFAAMGYAYGPAFRNLRAAWRDGDELFVELALAEG
PQADAAHFGVHPALLDAGLHGLALGSFLTGGDEEGGEGDRIRLPFSFTGVGLHAVGAGAL
RVRLAPAGSAGVSLTAFDERGEPVVSVESLLLRALDPARLHAARPTFHESLFRLEWPATA
GNPASPSGRWAVVGTDTFGLEAALLDAGITADVYTDLDVLAGVVLAGKPVPDTVLVPYAT
DPAADTAGATREATHEALKLVQTWLAEETLAGARLVVVTRGAVEARPGEGVADLPGASVW
GLLRSAQSENPGRFLLLDLEAGPDGAAGGAAAGFAPLLAAAVAGGESQVAVRDGVPHAAR
LARIPTARPEADGADLGAPAAVLDPDGTVLITGGTGVLGSLLARHLVTERGARRLLLTSR
RGPAAAGAPELVAELAALGAEAAVVACDAADREALAALLAGIPAEHPLTAVVHTAGHLDD
GLVPSLTPERIDAVLRPKVDAALHLHELTRDLDLAAFVLFSSAAGTLGSPGQANYAAANA
FLDALAQRRRAAGLPAVSLAWGLWEQRSEMTGDLTDADVQRMARAGLAPLSSEEGLALFD
TACALSAPATGADAGADAAGEPGGPDGTVFVAMRLDTGPLRAQADAGGLPPLFRGLVRGG
LRRAAAAGVADAAVSAAARRLAGLSGLPEEEQERVLLEVVRTTAAAVLAYPSPDAVGESQ
QFLELGLDSLTAVELRNQLNAATGLRLPATLLFDHPTPLLVAARLRAELAGAPGGPAGPD
GAAEQGGEEDAGVFGSMLREAGTQGASGQFMELLMQASRFRPSFASAAELRKAPSLVRLS
RGGTRPGLVCFSSILSISGPHQYARFASAFRGRRDVHAMAAPGFLRGEQLPSTAEAVIEA
QAEAVLRHADGEPFVLLGHSSGGMLAHAVAGRLEGAGVFPEAVVLVDIYSHDDDAIMGIQ
PGLSQGVDERQGSYVPVDDSRLLAMGAYFRLFGGWKPEAVKAPTLLVRAQEQFFDWTRAT
DGDWRSYWDLEHTAVDVAGNHFTMMEQHATTTAGTVEEWLDAHL
>A0A3N6DS49|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI91-18|TrEMBL
MAGLDPAAHPLLGAAVTLAGSDRVLCTGRLAPRTQPWLADHTVAGTPVLAGSAFVELAVR
AGDQAGCGHVEELVLDAPLTLPADGGVRIQVLVEDPDEQGRRVFTVSARPEGEAADDTGW
TRHAHGVLAPAESPAAGVGLAQWPPAGAEALDISGLYATEGATEGATEGATDGATEGDAP
ARGPLFRAVEAAWHHDGTYYAQLRLPEDAPQAADFGLHPALLDAAAHTALALAAPYADGA
GSGVGPGSVWSDVTLHATGAGALRVRIRPAADGAFALDLADDLGDPVATVGLLTPRPFTA
GTTGAPAAVPAVVREALFQLDWTPLPLPARPEALAAPAGPEGGWAVLGSTGSGPGTRHAD
LAELAAAIDAGAPVPAYVLAPFPRQADGLAPDTLSEAAHRALALVRGWLADTRFETSRLV
VVTSGAVAGSGEGGTDLPHAAVRGLLRSAETENPGRFLLADVRDLADLDDPAGAALLAVA
LASGEPELLLRDGAVHVPRLRRTRSAATPTAGTGAAGPVVVDPNGTALITGGSGTLAGIV
ARHLVTAHGVRSLLLLSRRGADAPGAAERTAELAALGAEVTWAACDAADREALAAVLEAV
PAEHPLTTVIHTAGVLDDGVVGSLTPERLDTVLRPKAVAALHLHELTRELPVTAFVLYSA
IAGTLGSAGQANYACANVFLDALAQHRHHQGLPATALAWGLWADASAMTVGLDETQLRRM
EQHGVGALTSGDGMALLDAALASGRPALVPARLNPAALAAAAAPGPVAPVFRELLGPAGR
RTARTRTDAGTPLAERLAALTRPEQDRALLDLVRAQVASVLGHASAEQVEPAKAFKDLGF
DSLTAVELRNRLGAVTGLRLATTLVFDHPSPTALARRLRTDLLGDEDEAAQDGPQGPRGA
APGADDAIAIVAMSCRYPGGVRGPEELWRLVETGGDAIAGLPGNRGWDTAELHAGQDGRT
FTGGFLHDADSFDADFFGISPREALAMDPQQRLLLETSWEAIERAGIDPSSLRGTRAGVF
VGASAGGYDAQLERSADVDGVLGHVMTGNAGSVMSGRVSYALGLEGPAVTVDTACSSSLV
ALHWAVQALRGGECSIALAGGVTVMSTPGTFSEFSHQGGLAPDGRCKAFAAAADGTGWGE
GVGMLLVERLSDAQRNGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRAALATAGLS
AAEVDAVEAHGTGTRLGDPIEAQALLATYGQDRADGQPLLLGSIKSNIGHTQAAAGVAGI
IKMVMAMQHGVLPQTLHVDEPSPHVDWSAGDITLLTRATAWPETRRPRRAAVSSFGISGT
NAHTIIEQAPEPAERPAPTATPVPVPYVLSARSPQALRAQAARLLPVAEEAVAADGSGLP
DLAYSLATGRAGLEHRAAFAADDREGLLRALAGLAADEQPPGLIRGTVSGGGLAFLFTGQ
GSQRLGMGRALYAAHPVFAAALDRVCEWFDLELPLKDVLFGTDAEVLDRTEYTQPALFAV
EVALFRLLTSWGLRPDFLSGHSIGEITAAHVAGVLSLEDACALVAARGRLMQALPGGGVM
IAVQASEDEVVALLTDRVSIAAVNGPRSVVVAGDEDAALAVAAAFPDRKSKRLTVSHAFH
SPHMDGMLADFRKVVEGLTFQDPRIAVVSNLTGALVSDEMGSADFWVRHVREGVRFLDGI
RALEAAGVTTYLELGPDGVLSALAQDCLTEDAAFVPVLRAARPEAEAVTATAALAHAYTR
GVPLDWRAYFAATGTGAHRVDLPTYPFQPVRYWPEPAAPGGAAQSAPAAAGADARFWDAV
ERADLTALADEFDLEGDQPLSTALPALSAWRQDQQARAKAESLLYRVTWQPWSGPDRGTP
AGTWILPVPAAQAQDPWVRALTDRMSGDGARIVPLPLDVADGDPAVLRAHLAAAGPVNGV
LSLLALDERPHPEHPSVPVGLALTAALATALTSEPDADADQPNGYANAPLWCVTRDAVAA
APADTLGGAAQSQVWGLGRVISLEHPGSWGGLVDLPEVCDERALSRLSAVLTGAGDEDQL
AIRAAGPLVRRLVHAAPSAGARTAPRWTPDGTVLITGGTGALGRHVARHLAARGARRLVL
VSRSGADAPGATEVRAELEALGAAVTLAACDVTDRDALEALVAGLAADGAPVRAVVHAAG
VSQPPGTGTDLPGFARVVTAKTAGAVHLDALFDTPDSLDAFVLFSSIAGVWGSGGQGAYA
AANTFLDALAERRAARGLAATAIAWGPWADGGMAAEGDAEEQLTRRGLPPVDPGTNLLAL
ERALAGRDAAVTVASVDWARFAPVFAAARPRPLVGDLPEVRGVLREEPHAAGTSADAAAT
VLGRLGELPADERDTALLDLVREHAAAALGHPSADAVAADRAFKDLGFDSLTAVELRDRL
GAACGLRLPSSLVFDYPNPQALTRHLLRTLFPEGSGGAAVTDLDSDPQDAELRRTLATIP
LGRIREAGLLDTLLRLAGPDAPATEPGAEAVDPGGSIDTMDLQDLLDLALDGGGGLDDDT
PDTTTSNSNF
>A0A2S9XYI4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Enhygromyxa salina|TrEMBL
MTKDKDSSKVSARVRDALLRAKARIQSLESQLHEPIAVVGMACRFPGGSTPAQYWDTLIQ
KRDMVRELPPQRSVGPWPEGVPRWAGILADDEVDGFDPAFFGITPREARSLDPQQRLLLE
VAWEALEHARMIPASLRASKTGVFVGLCTVDYGDHVEAQAADELGPFDTTGVMASTAAGR
LSYVLGLQGPAMTVDTACSSSLVTLHLACQSLRAGDSELALAGGVNLILSERTTAAIART
QALSPDGRCKAFDASANGFVRGEGCGLLVLKRYADARRDGDRVLGLIRGSAVNQDGRSAG
LTAPNVLAQQELLGGALDNAGLEPRDVGYLECHGTGTALGDPIEFEAIKAVYGRPREDDS
RLWLGAVKTNIGHLEGAAGVAGVIKVLLALAHRQIPTNLHLRHVNPRINLAGTPLALPRD
AVEWAAIAGRRVAGVSSFGMSGTNAHVVLEGPEPAAPAEPAEPAAPAEPAAPAEPAEPGA
AALAPPPSVPLLISARHLDALAGQAARLRDRIAADDARLVDVAFSLATARTHFEHRACVV
SSTPRAALEDFARRGQDPSVTTGVAKGPVKLAVLFTGQGAQRVGMGRSLYESSPGFRAAF
DEACGHFDELIGASLRDIVFAEPGTNAAALIDQTRYTQPALFVVEYALYRLLESWGVRPS
IVLGHSIGELVAACVAEVMSLADAAKLIEARGRLMQALPSRGAMVSIQASEAEVRPVVER
HRGLDIAAINGPTSTVVSGDEDAVEAVRAHFEALQRKTRRLTVSHAFHSHHMEPILDPLT
RVARSISFRPPSIPIVSNISGAIAGAELHTDPSYWARHVRSPVRFLDSVRALRSAGANVL
VEIGPHGVLSSMAAACLPEGELDDTTIISTMRKHRDEHQTLLHALGSLHCRGVDVDWPAV
LSPYAPRLIDLPTYAFRRDRYWVTPDEATPGRAPGAGPDADAFWAAVGHGDLDSLAAQLE
LDDERRAALGSLLPSLSSWRLRQRSNQWRHELRWRPAARHLDAAVPEGGLVVVPASLAAS
SLVTALVDALGHPRTLALPLAATRTQTATALRDALAPRPAYLLSLLALDESRHPEHSTTP
VGLALNVHLSQALVDLDVRAPLWLVSQGAVSVGDADPLTNPSQATSWGYGRSFSLEHPAH
WGGMLDLPAEPDAELLGLVGAVLGAAEIENQLALRAEGLFVRRLVHAAGPEPSTAAFEPR
GPVLITGGTGALGAHVARWLAELGAGPLVLTSRRGADAPGSASLLDELEARGVSASVVAC
DVGSRDSVERLFADLERDELTPRIVIHTAGVVDDALATELTPERFARVLAPKLDGTLNLH
EATKQLSLDHFVLFSSLAGTLGNPGQSNYSAANHFLDAMAAHRRSLGLPAIAVAWGPWAG
GGMATDVAMDAAVSAMDPAMAIAALQASLREGHTNDAIIDIDWPAFARAHLRGSARHLLD
EILPPEPNESVADDSRSLLDELPTVPVEDRAQFVREFVARQVAAVIGSADTDALDPEVDF
SELGVDSLMAIELRNRLQATTQLSLDATLTFDHPTLEQLAASLHEQLSARMAARKPAPAR
PNAGESKGDVWVDMWRSTREERLAQSSEWHSAFTRLVTNRHERFRTVLDLFDNFADIRRM
QDPEARAPVIPRPVLLSRSNAGLQIYCPPSYGPPASAFQYFQVARSLGDRASVWATSMLG
YSIEDPLPETWHDQVMHQYEALQQCLDPSRPWVMLGHSAGGLLAYHVLAHIEATGANRPV
AMILIDSAYPGTSDDELLYPPFVRSTTQHLIGTGSDRVDSEYLYQFSAFRWNAKLCDAAW
ETPRPRIETPSLYIHCAAFSETVAFANDLTPWPALFDRLDIIKTEVNHFGIITDRSDHVA
DLVLRWLERLDPSDSDGGASFVGDGS
>E6U7C1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ethanoligenens harbinense (strain DSM 18485 / JCM 12961 / CGMCC 1.5033 / YUAN-3)|TrEMBL
MNSLFELIDFDDIETKKPEADKSAPGENHSADEIAIIGAAVKLPRADNLRELWNNLLFGI
SACSDFPDQRYRDIENWFKCRNIRLTPQMFKKGNYLTDIDKFDYDFFGLSADDANMMDPL
HRLLLETFWNCLEDGGYCMQKVSGTCTGIYVGFNNDDIERYSRMLQEKRVRFTMATMENN
LSSILASRLSYLLNLKGPAMLIDTACSSSLCALHIACQGLKNEDCEMALVGGINIGMVPI
KYEGFRVESESDTLSPFDDSADGTVWGEGVVSLLLKPLRYAVRDRDHVYAVIISSAINQD
GMSVGISAPNAVAQRNVMVNAWEKAGINPEEISYMEAHGTGTKLGDVIEMEGIRQAFERY
TDRKQFCGIGSVKANIGHIEGASGLAGVVKLMLSLQNRVIPKTIAFNRPNHSIAFEDSPV
FLVDRLTPWESTGGRRTCGISSFGLSGTNCHAVLREFSKDAPVSPEPAESAPYLLAVSAK
SAYSFQQLLRAYAELLVENPAIDLESMCYTAGYGRDHHRYRAAFVFTQKRELLDALKSAW
NGDAARFDTNGLLRSEEKEALDREADRLVLDASQKRGGECHQSYLDISRLYCRGAAVNWK
LLYKNRAVKTLSLPVYPFERHRCWI
>A0A1Q2ZKL5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MPATPSDLVRPLPELLRGHAESRGTKVAFSDTRTSLTFADLDLRTARLGGHLAALGLPRG
SRVAILLGNRVEIVESYLGVNRAGCVGVPVNPHSSDAELTHVLTDSDALAVITDTAHAAQ
VRTALPPGERHVIVVDESYEDLVTRDPATGPRDDLGLDEPAFLLYTSGTTGLPKGVLSTL
RAVLWNVTTCYTPIIELSPDDTMLWPLPLFHSLGHNLCVMAVTAVGASAHLVPGFSAAEV
LDELRARPYSFLVGVPTMYHNLVHAAGTEGLQLPALRVCFVAGAVTTPQLAASFEAAFGV
RLTDNYGCTETSGPMATMRPGGEPRPGSCGLPLPGLDLRVVDPETGTDVPTGAEGEIWVK
SPNVMLGYHNRPDATAEALKGGWYHTGDLARRDDDGYLYITGRRNNVIIRGGENVHPTEI
EAVLFKVPGVREAAAIGVPDEEFGQVPVALVVPGPDGVDCADLFARCRRELAYFKVPVEV
RAVRELPKTATGKVIRRLLPDLPGRLLGVSGVHEGLQLVGTGGELTSLSGTEPLPSLAGR
EVTVTGGRLADLIAGHLVEGHGARRVTGDQYDLAVTVTGTTVTVAGTTLVLADGLTDRRV
LDALDVALGHPGATLVTAVRSAAPERLPEKADLTGTSLVDVITREVTHVLGDPVGIEPDR
ALREYGLTSADAVRLRDRVAAAVGLRLPTTLVFDHPSVRAIAAYVHGELTGSTETLAPTA
VHAAADDDPVVLVGLACRYPGGVTTPDELWRLVADEADAISGFPDDRGWDLERLFATSTT
RHGGFLHDAAEFDAEFFGISPREALATDPQHRLLLETAWEALERAGVDPTALRGERVGVY
AGLMLHDYISDMERVPRELEGYLATGVQGGVASGRIAYTLGLRGPALTVDTACSSSLVAM
HLAAQAIRRGECDLALAGGVAVMGTPQGFLEFSKQGALAEDGRCKPFAAGADGTGWAEGA
GMAVLERLSSARRAGHPVLAVIRGSAVNQDGASNGLTAPSGTAQREVIRLALQDAGLGPD
DVDAVEAHGTGTRLGDPIEAGALLATYGQGRSAPLWLGSLKSNLGHTQAAAGVGGVIKVV
QAMRHRTLPKTLHVDAPTPHVDWAAGDVRLLTESMPWPERGRPARAAVSSFGISGTNAHM
ILEEPPQEPAPTAAPEPEVVALTLSGKSPERLRDWAARLLPVVETASPGDLAHALAGRSR
FPHRAVVVGGELASGVRALADGKSAANVVSGTADVDGKVVFVFPGHGSQWVGMAAGLMGQ
SVFAESILACERALAPHVDWSLTEVLADPERLDRTDIVQPALFAVTVSLAALWRAHGVEP
DAVLGHSVGEVAAAYVAGALSLEEAARVVAVRGQVIAGLGGGTGMVAVPAPREQVDWLVE
RWPDQLWVAGLNGPSATTVAGDEIALKGLLAECALDGVRARRVRVGYASHSPRMEALREE
LLAQLGSVRAGTPSVPMYSTVDLEWVGSGALDAEYWYRNLRAPVRFQPAVERLAADGFRV
FVESSGHPALASAMEETLAGVGVNAVVTGTLRRDDGGPARFLSSAAELYVRGVDGVRLTP
PAGRAVALPLPTTPFRRRRFWLTTGGAARTRNGHPLLGAVVESARSGESVATSRISPVDL
PWLADHAVNGTCLLPGTALLDLALRAGGGGVDELVIEAPLVLSRQGVTELQVVVDGERRT
VEVYSRPDQAGARWRRHAQGTLCAGGVEPSGVAELVPSDAVKVHVDYSALTSLGYEYGPA
FRGVRRVWRRGAELFAELRLPEESPGGLGGVGLHPVLGDAALHALVFTDDSAEGEVRLPF
VWRDVWAGERQETEAYVHLVPSGASDVGVSIFTVAGEPMFRGTLGMRAVALRELTGAVPT
DSVYRMRWAELAGPVGESGVEPVVFAPPAGDVRKAVLDTLARLQQWLEGEQDAPLAVVTQ
SGDLAHAAARGLVRSAQAEHPGRFVVVETDGDARSSARIGDAVGAGEPHVRVDAGRLQRP
ELARVAPGRGERPSLAAGTVLITGGTGTLGSLLARHLVSEYGVRSLLLTSRSGGGEALVE
ELRGLGASAVVAACDAADREALAGALSLVPASHPLVGIVHAAGVLADGVVTGMTADQVEE
VLRPKVDGVLNLHELTKDADLAAFVLFSSVAGVLGSPGQGNYAAANAFLDAFAEHRRAEG
LPVQSQAWSFWEEISGMTSAVRDRDFPDGTLPLPTPFALALFDEALRQDEAALTLAKFDL
AKLRTRGAPGLLRGLAPARPATAPTVALRDLPPTERAAQLLTEVRAIAAELLGHADAEAI
SLDRSLHEFGLDSLTAVELRNRLSTLTALRLPATLVFDHSALRGLAEHLDGELTAAMEAE
V
>A0A1Q2Z3F7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MVSEEKLVDYLKRVSADLHTTRQRLREAEERAQEPIAVVEMACRYPGGIRTPEALWDLVA
TGRHALGPFPENRGWDLAALFHPDPDHPGTTYAREGGFVHDADLFDPEFFGISPREAQAL
DPQQRLLLECAWEALERAGLDPRSLHGSRTGVYAGAALPGFGTPHLDAEAEGHLVTGSAP
SVLSGRLAYTFGFEGPAVTIDTACSSSLVAVHLAAHALRQRECDLALAGGVTVMTTPYVF
TEFSRQRGLAADGRCKPFADAADGTAFSEGAGLLVLERLTDARRAGHPILAVIRGSAVNQ
DGASNGLTAPNGLAQQRVIRAALAGARLSPAEIDAVEAHGTGTRLGDPIEADALLATYGQ
ERHDEKPLWLGSVKSNLGHTQGAAGAAGLIKMILGLRHETLPATLHVNSPTAQADWASGD
VRLLTEAVPWPRGERTRRAGVSSFGISGTNAHVILEEAPPEEPADEPVRREPGGHPNLPW
LLSARTVPALRAHAGALAPHLDDPTAAVAATLSHRTLFEHRAVVLGTDREERAQALAALA
EGRPHPALVRPPGAARTGTTAFLFTGQGSQRPGMGQELYAAFPAFAEALDDVCAHLDPAL
KRTLFAPPDSAEAAALNETGTTQTALFALETALYRLVTSFGVTPSHLTGHSVGEIAAAHA
AGVLDLPDACTLVAARGRLMQALPPGGAMLAVQATETDVLPLLTDRLALAAVNGPTSVVI
SGDATQAATLEHTLRARGLRTKRLNVSHAFHSPLLDPMLDEFRAVVRELTFHPPTLPIVS
NLTGALADAQTLADPEYWVRHVRRPVRFFDGVRALDAQKVVRYLELGPDPVLTTMVRDCL
PSTEPVVTTALRTGHDETRTLLSALATLHTDGQPVDFTPLVPPGTDHPHLPTYPFQRRRY
WRSAPHTPTSAVDLDDTGHPLLPVAVQQADGGLLFAGRLSPRTHPWLADHTIGGAVPFPG
TAFLELALSAARFTQCDTIDDLTLETPLLLDDNGTVSLQLTLAAPDSTGRRTLAVHARTD
DEWHRHATGTLTASTDTHPPTPTTWPPTDATPVDVDALYTRLDEQGYAYGPAFRAVRAAW
RHGDDLYADVHLTEPADGFTLHPVLLDAALHAVDTLYPHDDRQVRLPFSFTGVRQYTTGA
TTLRAHLTALADDRLRLDLTDTDGAPVATIDTLRLRRIATGHWRTSIPLHHLEWQQLPFS
FSGEASEAESDFVFAAFPAGDDPAQARTHAHQALRLVSDWLATDTEARLVVVTEGAVTAR
PDDPPPDLATAPLWGLVRAAQAEQPGRILLLDTDQDPASRAAQSAALAAATARNETQLAL
RDGTALVPRLAAVGQSEATAPELDPERAVLITGGTGGLGQTVARHLAAAHGARHLLLAGR
RGPDAEGVAELRDDLAELGVEVEAVACDVTDPEALAELVGSRALTAVVHLAGIVDDSLVT
AMTPDQLDAVLTPKADAAWQLHRLTQDMDLAAFVLFSSAGSVLGAAGQANYATANAFLDA
LAEHRRAEGLAATSIAWGLWESAAGGMAARLDDTDRARIRRTGVAALTDEQALGLFDAAL
TAARPAVLASRFDRAVLRDDMMSPVLRGLVRTPRPAPVTREEETTWAAHVAALPDTDRER
ALTELVREQVAIVLAHPTPGAIELDRAFHELGFDSLTSLELRNRLSTATGIRLPATLVFD
HPTAKALVNHLRAQLPGAGAGAAKAIEATTVRAATDDDPIAIVGMACRYPGGVTSPEDLW
RLVRDGGDAIGPFPENRGWNTAELFDPDPDQVGHSYTREGGFLYDAGEFDAEFFGISPRE
ALAMDPQQRLLLETAWHAFEDAGIDPATLRGTSCGVITGIMYDDYGSRFLARKPEGFEGR
IMTGSTPSVASGRVAYTFGLEGPAITVDTACSSSSVAIHLAAQALRQGECELALAGGVTV
MATPNTFVEFSRQRGLAPDGRCKPFSAAADGTGWGEGAGLVVLERLSDARRRGHKVLALL
RGSAVNQDGASNGLTAPNGPSQERVIRAALAGAGQRAADVDAVEAHGTGTVLGDPIEAGA
LLAVYGQGRAVERPLWLGSVKSNIGHTQAAAGVAGVIKMVMALRHEVLPVSLHAEVPSGH
VEWDGGGVRLLSEAVGWPRGERVRRAGVSSFGISGTNAHLILEEAPGGEEGASVEEPEVV
PWVVSARSSGALEEQVRRVRELEASAVEVGWSLVATRSVFEHRAVIVDGDVVSGVAGDIG
PGPVLVFPGQGSQWVGMGAQLLDESPVFADRIAECEQALAPHVDWSLTEVLRGGRELDRV
DVVQPVLWAVMVSLAAIWEGYGVVPAAVIGHSQGEIAAACVAGALSLQDAARIVAVRSDA
LRQLQGRGDMASIGTGPDEVRALIGDHRPGVSVAVVNSASSTVISGPPAEVAAVVSEAEA
RGLRARLIDVGYASHNAQIDELREELTRRLSDVRPSAVSDVAFYSTVTAGRIDTTALDTE
YWVTNLREQVRFAETIAALQADGYRLFIEASPHPVLVLPMEETIDTGTVVPTLRRDHGGT
KQLTLAAAQAFTAGADINWHRWFPTPPHTIDLPTYPFQHHHYWLAPPTTPTDATDLGMTP
LDHPHLTATTELPASDAYLLTGRLTHETSPWLAEHVVAATPLVPGSALIEWLLRAADEAG
CPTLDEVTLTAPLPFPDSGTTQLQITVGAADDEGRREVRVYARRDTAWVCHATGVASPEP
PVPAAELAPEWPPVDADPVDVEDFYPRAAQTGYTYGPAFQGLRKLWRHGPDLFAEITLPE
QAGPHDGFGIHPALLDAALHPLMLLDPPGNGRLWLPFAWTGVTLSATGATSVRVRLTPRG
ETVGVTITDSTGAPVLTTDALTLRAVAPGQLAAGVEGLYAVEWTPLTAPHDEGEETLVLA
VDGEELPSVAKVLAEVQEFLDSSEESRLTVVTRGAVAVDGGDVDPSAAAVWGLVRSAQTE
HPGRLALLDTDGGELPRLPGGEPQLALRDGALYVPRLTPVTPPDDLLPPPDTSAWRLTTT
GPATLDALAMTEAPEALAPLAPGQVRISVQAAGVNFRDVLIALGMYPDEGTFGGSEGAGR
VTEVGPGVAHLKAGDRVMGLFEGAFGTLVVADARMIVPVPEGMSLREAAAVPVVFLTAWY
GLVELGGLGAGESLLVHAGTGGVGMAAVQIARHLGAEVYATASPAKHAVLAELGIDEAHR
ASSRDLGFAEKFRGRVDLVLNSLAGEFTDASLRLLAGRGRMVDMGKTDKRDAGRVAAEYG
GVPYRAFDLVPDAGPVRIGEMLAELGELFASGALTPLPVRSWPVGRAREAFRFMSQAQHT
GKLVLDIPPALDPDGTVLITGGTGVLGTAVAEHLVREWGVRRLVLASRSGGGEGVVEGLD
ADVSFAAVDVTDADAVAELVACIEGLTGVVHAAGVLDDAVVTAQTPESLAKVWAVKAAGA
RHLHEATRDLGLDLFVVFSSAAATLGSPGQANYAAANAYCDALMQHRRAEGLPGLSIGWG
LWRTASGMTGHLNDTDLARMKRTGFTPLTTEHGLALLDAARAQERPHVIAVDLDVRAVAA
PPPPLLRALATKAVTARRTAATGTAAVDGFADRLAALPPAGRHRLLLDLVRSHAAGVLGH
ADHDAIRPDTSFKELGFDSLTAVELRNRLAAATGLKLPAALVFDHPESSALAGHLLERLD
GTPAPPKDPVGPLLGELGRIESSLTTLALDDEARGRITRRLTTLLTKLNGAPDLEALDTV
SDDEMFELIDREL
>A0A100JGD4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MSGGEVPWVVSARSSGALEEQVRRVRELEAPASEVGWSLVTTRSVFEHRAVIVDGDVVSG
VAGDIGPGPVLVFPGQGSQWVGMGAQLLDESEVFAARIAECEQALAPHVGWSLAEVLRGG
GELDRVDVVQPVLWAVMVSLAAVWEGYGVRPAAVIGHSQGEIAAACIAGVLSLQDAARIV
AVRSDALRQLQGRGDMASLGVGTDQAAELIGDRPGVSVAVVNSASSTVISGPPGEVAAVV
SEAEARGLRARLIDVGYASHHAQIDELREELEERLSGVHPGAVSDVAFYSTVTASRIDTA
TLDTGYWVTNLREQVRFAETIEALQADGYRLFIEASPHPVLVLPMEETIETGTVVPTLRR
DHGGTEQLTLAAAQAFVAGADINWHHWFPTPPHPIDLPTYPFQHHHYWLKPPSAPPFTTT
SADPIEAQVWQAIEDLDIEALTGSLEIEGRPETVGVLEPALPVLSAWRRRHRERTTLNSW
RYRITWKRLPDTTAPHVTGTWLLLAPTTHPDHLAVRATAQALTAHGAEVRQHLIDTRSSE
PPELDTSGLTGIVNLLALDEDPHPDHPAVPAGLAATTALIQVLAATETPLHTITQGAVGD
TLTNPIQAQVWGFGRVAALEYPRLWAGLVDLPARVDHQTLPRLAAALLRQDEDQIALRPT
GTYARRLVHAPADRGTAPSWRPEGTVLITGGTGGIGAVLARWLAHQGAPHLHLISRRGPD
APGAHQLTTELTDLGTHVTVTACDVSDRDQLRDLIDTHPPTAIIHAAGVPNYIGIAELSG
AALDEVLRPKALAALHLHELTRELNLSAFVMFSSGAAVWGSGQQAAYGAANHFLDALAEH
RHALGLPATSVAWGPWADAGMAADQATLTFFSRFGLQPLAAELCVKALHQAISSGEPTLT
VADFDWARFTPTFTAQRPSPLLADLPENRRESAPAEQESGAAAGSSQELQRELASANPVQ
QRQLLLQHVREQAAATLGHADVDSVPASKPFQELGFDSLTAVELRNRLNKSTGLTLPTTV
VFDHPTPDALAGVLRAELSGEAAAVDVARAAVAVADDEPIAIIGMACRYPGGVRSAEDLW
ELVADGRDAMGGFPDDRGWDLEKLYDPDPESRGTSYVREGGFLYDAGDFDAEFFGISPRE
AVAMDPQQRLLLETAWEAVERAGLDRGTLKGSDTGVFAGLTIFDYLALVGEQSTEVEGYI
GTGNLGCVASGRVSYVLGLEGPAMTLDTGCSSSLVAIHQAAHALRQGECSLALAGGATVM
ATPGAFIEFSLQRGLARDGRCKPFAAAADGTGWAEGVGLVVLERLSEARRNGHRVLALIR
GSAINQDGTSNGLTAPNGQAQQRVIRQALANSRLSGEDIDAVEAHGTGTMLGDPIEANAL
LATYGQDRPGDRPLWLGSVKSNIGHAQASAGVAGVIKTVMAMRNELLPRSLHIDEPTPHV
RWDGSGVQLLSEAVPWTRGERPRRAGVSAFGISGTNAHVILEEAPPSEEATSAKEPELVP
WVVSARSEAALGEQVRQLGELEASATEVGWSLVTTRSVFEHRSVIVGEDTVSGVAGDIGP
GPVLVFPGQGSQWVGMGAQLLDESPVFAERIAECERALAPHVDWSLTEVLRSASELTRVD
VVQPVLWAVMVSLAAVWEDHGVRPAAVVGHSQGEIAAACVAGALSLQDAARIVAVRSDAL
RQLQGRGDMASLGTGADQATELIGNRPGVSVAAVNSASSTVISGTPAEVAAVVAEAEARG
LRARLIDVGYASHHAQIDELREELTQRLSDVHPGTPSDIAFYSTVTASRIDTTTLDTDYW
VTNLREQVRFAETIKILHQDGYRLFIEASPHPVLVLPMEESIDTGTIVPTLRRDHGTTHQ
LTLAAAQAFTAGADINWRRWFPAVPPPRVVDLPTYAFQHQRYWLDGPRGVAGDPAGFGLV
PAGHPLLGAVVELADGDSRLLTGRLAARDQAWLAEHQVMDRVLLPGSAFVELALQAAVRS
GCDEVSELTLHTPLVFGDEGAVDLQVVVGVAEEDGRRSVAVHARPVGEPAWTRHAAGVVA
RAGTDAVEPEFGGVWPPPGAVPVGGDDPYGELSSYGYEFGDASRGLVGVWRVGDDLFAEV
ALGEVQGAEAGRYQVHPVLFDSVLHAVVLDAVGSSAASGDVLLPFDWSGLRVFVPGAERL
RVRVVRVAADRLALSAVDELGVPVLALESLTVRPVAARQIVGARAERDALFRSVWREAEI
SGGAVRAGVVAAGGSSVLAGVPVCGSLDGLRDDVPDVVVVECAASGAGASGAVVELLGVL
KEWVDDPVFAASRLVVVTRGAVVARPGEGGGEPAGAALWGLVRSAQAENPGRLTLVDVDR
DADSLAALPGVLACEEPELAVRAGRLLVPRFVRDDASGRLVAPVGSSWRLEWSGGQWGVV
DAPECGREVAAGEVRVAVRAAGVAGAGVVTEVGAGVGGIAVGDRVMGGFGVVGPVAVVGA
GTVAPVPEGWSWARAAGAVEVWDVRQAPAAPPSAVFVLPVPFDPEGTVLITGGTGALGAL
TARHLVSRYGARHLLLCSRRGADAPGALELGAELSALGARVSFAACDPGYREAAEALVAS
VPAEHPLTAVFHCAGTVSDAVVQNLTAEQVEEVMRVKAQAAWHLHELTRDMDLSAFVLYS
SVAGLLGGPGQGSYSAANAFLDALAVHRYAGGAHAVSLAWGYWDLPDGMSGRLTDADRAR
HARAGVVGLGAEEGLALLDAAWASGLPLLAPVRLDLGRLRREAGSRLVPALLRDLVRPAK
AGGGVSAGAAALRKALGTASEAERERMLLDLVCTQVAAVLGHDAATSVNASQGLRDLGFD
SLTAVELRNRLSAATGLKLPATFVFDHPDPAALAARLGAELAPRAVDPLAGVLAEFERLE
GSLLAVSSRDGGARLELAGRLRATLARLDVPSGAADGSAVAARIQDASAEEILAFVDRDL
GRDSGNGRTVEGQR
>A0A100JDK2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MTIDVPDSPAPTLAEKGETLRNRLADLQPAEQHSLLLDLLKEQISRAADGDGSGLVDVRA
PWRRLGVYRQRAQRLRDGMAEATGLRLPATVLFDYPTPLALAEHLRHELLGPGTVRDTAG
VVDGGRAGTADDPVVVVGLGCRLPGDVDSPEALWQLVAEGRDVIGDLPDDRGWDLEGLYD
PDPERHGTAYTRHGGFLKGAEDFDPGFFGIGPREALALDPQQRLMLEISWEALERAGIDP
HALRGSSTGVFAGVSLQDYGPAWHEAPQEAQGQMLTGNALGVVSGRVSYTFGFEGPALTV
DTQCSSSLVAMHLAAQSLRAGECDLALVGGVTVMSTPGMLLEFSRKRGLAPDGRCKAFSA
DADGTGWAEGAAVLLLERLSDARRAGRRVLAVVRGTGTNQDGASNGLTAPNGPSQQRLIR
RTLASAQLGPADVDVVEAHGTGTALGDPIEASALVAVYGQERPEDRPLYLGSLKANIGHT
QAAAGVAGVIKMVMAMRNELLPRTLHVREPTPHVDWSAGSVELLREPVPWPRAGRPRRAA
VSAFGVSGTNAHVIIEEPPGPGPDPEAALLPVVLSARTGQALRAQAKRVAGHLAGHPDLS
LAGVGATLAGRTRFEHRAVAVAADRDELLGALEALGEGRPAMGLVQGEGGPAGDGGKLAV
LFTGQGSQRHGMGQRLYRTYPVFARALDEVCARMDQHLQRPLRDVMFAAEGATDAELLHR
TAYTQPALFAHETALFRLAESWGVAPDLLIGHSIGELTAAHVAGVWSLDDACSLVAARGR
LMQACRSGGAMTAIQASEEEVLDTLTGLDGQAGVATVNGPLATVVAGDEETVARIAAVWE
ERGRKTKRLNVSHAFHSPHMDDMLAAFREVAEAVTYHPPQIPVVSNVTGERAGEEQLCSP
EYWVRHVREPVRFLDGMRCLYREGATGYLELGPDAVLTALGPGCLPEDADGLVMTSACRA
RRPEDRSLLAAFAELHVHGFPVDWQTPYDGLGTDHVDLPTYAFQRRRYWMERPARTAAPA
QEAPRQHRTDPAGWRHRIAWQPVELPVLPSLSGVWLLLVPPLGADEELLSRVAWVVELLG
GEAVRVDLRADDADRAELTEMLEKQVTTAGGRLGGVLSLLALDTTPHTEHPVLSDGIALT
CALAQAMADLDLDAPLWCATRGAVATDDTEQAVDADQAMLWGLGRTLAVERPHAWGGLID
MPAELDDESLHLFGAALTAPGDEDQLAVRSTGLFAGRLVPAEPTDSRATSAVPAASSALP
ADVSATPWRPRGTVLVTGGTGALGAHCARWLARNGAARLVLTSRRGPDAPGAAGLRAELS
ELGAKTVIVGCDAADREQLAAVLGSLPEDQPLSAVVHAAGVMGRFAPLPETDLAGFAEVV
AGKVAGARHLDELLGDTELDAFVMFSSVTGIWGSSGQTAYAAGNSYLDALARQRRARGLA
ATAIAWGPWAEAGMGAGDGVRDFLTRRGLRHLAPEDAIAEMERAVAAGETGLTVADMDWD
HFVQLRRTIRADRFFDVVRPPADGLSAPGESSEESSVDPAARVTDARAALELVRAEAAAV
LGHGSSDDIDPGRRFLELGFDSLASVDLRRRLAAATGLALATAVVFEQPTATELARHIET
LARRAVEERTAPAPSDPPVPGVRDLYRHGCKVGMYSEANRILQAAAKLRPVFHTPEEYDE
KHGVAREVRRLATGPAGATALVCLPPVVAPSGPHNFARLALHLHGLHDVYGLSYPGFGDG
EPLPASSDLIVDTLTEAMARRFADTPIALAGYSSGGWLAHAVAHRLEQRGLAPKAVVLLD
SWFPKDRVPREKVEEQFRNIAVNDGVWGLITDDQATAQGAYLELLEHWEPRPVTTPVVLV
SAQERWFGGTDEDAVSTHDWSPAWDFAYDTVVTEGDHQSMMYEYAQTTAGALREWLRRV
>A0A0N0N8E5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OV320|TrEMBL
MHETNGPLDTPEEDLPAVAVIGMAGRFPGADDLDAFWDNLAAGREAVRPVTDEEFLAAGG
DPRDLDDPSLIRMASVVEGIDRFDSGFFGYLPAEAAVVDPQQRLLLETAYHALEDAGRLA
PGTDHGTFGVYAGAGDSRYYPAHVHPRHAGQPGSVELVHAATANSLGTLAPRISYELGLT
GPSVSLQTACSTALVAVHTACQDLLDHRCDTALAAAVSLNPSAALGYRHVPDGPFSPDGH
CRAFAADAAGTSSGDGVGAVVLKRLADALADGDHVRAVIRGSAVNNDGRRKVGFSAPSSA
GQTEVVLAAQAQAMVDADTIGLVEAHGTATRLGDPIEVAALTEAFRESTRRRGYCALGSV
KTNIGHLGAAAGIAGLIKAVLALEHRQIPPSLHFDRPNPLIDFAAGPFRVPTALEDWPAD
GHPRRAAVSAFGIGGTNAHVVLEEAPAPAPAPPRAPEEGGRLVLPLSARTAGALRGQAEA
LAHHLERRPGLRLDDVAHTLRTARPALRHRLTVSAASREEALSALRAAAPATPAVPDEPA
RVAFLLPGGGTQYPGMGAELYRDQDVYRDAVDECARILRPVLGTDLRTSLFEGAPADHTA
TFLGLVVTEYALARTLMAAGVRPDALIGHSLGEYTAACLAGVIDLADMLPLVTERIRLIS
GAGGATVGVAAPAEEILPLLDEELSLAAVNGPAACTVAGYEEAVARFERELARRDLPFRR
VRIPAAAHSHVLDPVLETYERHLHGVTLRPPRIPFVTSVTGTWITDAQATSVRHWLDHTR
RTVRFTDAVTALWERGRPVLVEIGPADTLTGLATAQLDPDTPVTVTTMRHAKSDARDGFV
LAEALGRLWSAGADTALPPVPGTPRPVPLPPYAFERHRHWIDAPGGRSTVSDTPDTVQDG
PHLAPRPRLTTEAVPPRTERERAVVRLWEQTLGIGGIGVHDNFFDLGGDSMRAVLLAGRL
RRAGVLDVPAATLLAAPTVTGVLAATEDTDDQRSGGAANALAPLLPLRREGGAAPLFCVH
PGAGVSWRYTGLLPHLGGDQPVYGIQAAGLDGTRPPAADAPAMVASYVDLVREVQPHGPY
RLLGWSYGGFVAHAMACALQEQGERVELLAMLDAPQPWASAYDAGTAERQVAALLMRVTG
LPVPPDGGPPAVATVLDLIDAKVTADPAASPVDRAQAAAVADVMRNNLRLAPRFEPGVFH
GDVLFFSADDEPATDFAGDLAVQPGKADAWRAQVRGTLHDHRVPCGHYEMTEPEPLALIG
TAVAKALRGTADPTAPLPVPPPGGPDSPGDPT
>A0A0N0NFT4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OV320|TrEMBL
MSELAKHSAPVAVIGVGGRFARAPDVGAFWDNLVAGRDCFRREPVPVVEDLGEDRLRVHS
WGTAPHRDTYDHALVGVEGLDPQHGILQESLWQAAEDAGVRLSAIADRTAVYAGCARTKH
VPRAAFDDVVQVDPTFAGPYFSYLQDLWGESLMLDSACATSTVAVQLACQSLRSHACDYA
LAGAVAIQEDADGSYLRTPRSIYSTEGIVRPFDRRHNGVVPGDGSGAVLLRRLDDALRDG
DPVYAVIRGGAVTNDGRAKPGFVIPGVDGKVRAVRRALEAAGLTGADVDYVETHGVGIPL
NDQIEATALIEALGTEGPPVAVGSVKASVGHCDTAAGMAALIKTCLAIDRGFLPATPNTE
VPIEEFTGRGERFGILPEGRPWPTNGRPRTAGLMSAGVGGTNAFLVLEEAPAH
>A0A045JNT1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MAPKQLPDGRVAVLLSAHAEELIGPDARAIADYLERFPATTVTEVARQLRKTRRVRRHRA
VLRAADRLELAEGLRALAAGREHPLIARSSLGSAPRQAFVFPGQGGHWPGMGAVAYRELP
TYRTATDTCAAAFAAAGVDSPLPYLIAPPGTDERQAFCEIEIEGAQFVHAVALAEVWRSC
GVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVAALGIGEQDAS
ALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVGFPVHTSVLES
LRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVESAIRC
GARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSAAVAD
PGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMVPSTP
VAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDAVRAA
GALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQVDAADAVPSAGQAALAAMHRSIGFEH
PEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSVNGYTLFERTLADAPAVPNWS
LDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAMLRKQHGTVIVS
PPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNFAAKVLGLAQM
IELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRHCVAVKWGLWQ
APKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAADAARLQMLLD
SRQFERYEGPTDPNLTIVDAVRTQLAAVLGIPQAGEVNLQESLFDLGVDSMLALDLRNRL
KRSIGATVSLATLMGDITGDGLVAKLEDADERSHTAQKVDISRD
>A0A378USU6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium fortuitum|TrEMBL
MREADALPDGRTPVLLSAHAEDLIGTDAAAILRYLENRAESGAADVAATLSSTRRLRRHR
AVVRAADRDELCAGLRALAQGAEHPLVTRANSGAPGSGSGARIAFVFPGQGSQWPSMGVQ
AYAQLPAYRAEVDRCAAEFRAAGAASPLDYLLAEPDSGAVTNDFSQVQIQGAQFVHGVAL
ARVWRSCGVLPDLTVGHSLGEIGAAYVAESITLSAAVAVVIARATVLDRLTGPYRVAVLG
ITPEEALGVIADTPGWLELSVVNSRASVAVSGETDAVAAVVATVAGRGSFAKQIEMWFPA
HTTALDGARGELASLLPEAAFSDSPVQFIGSATADVIEAGTGFADYWYTNLRSTVRFDRA
IETAARRGAGIFVELSAHPALLFAMGDLLDDAGEPTGRPAMIVGSGRRDEPITETLSANI
VSVAMADSGYRWADLSNHATVPLRNFPFAPMRAEHLWAAPQPLPPVPGLTVGVEHWEEVR
LDAPPGGQRRVAVLDLAAGQGSAAVLRDALSRAISECYHTVAAAPQHADLLVVVAPVSDD
TDPVAAAEALSCRIDQGLLGYAAGITTQTRDVWLVTVGGEQVGGQPQHARPEAAALAAMH
RSLGYEHPDQTFRHLDLPEPTLDRATASAAVTAMLTDTEDIALRGNGSELTAWRRSMRDD
TSDAMVWTADSGIFDEVVITGGAGAVGLHYARHLAERGARRIVLLSRSGIDAAQAAALAA
HGTEILAPRCDLTDPEQIAATVAELAVSPASLVIHAAASATIAAANELTGAAVRDTFAAK
VSGLANLASAWPMRPDARIMLCSSVSGLWGGSGHAAYSAANRLLDALGGQLREQGRQCTS
VRWGLWPGDGIIDSGEVSRVERSGLRAMAPDLAVEAGLRDYPADPLVFAADAARLQTFLG
AAARPGAAGAAAGALQDTTAEAADPTGAMRIALAAVLKLDDTTGLDLGTSLLDLGVDSLL
AIDLRKKLKKATGRSVPLATILGGATAAELIEHLERPEKEAFSRD
>A0A498QW36|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium pseudokansasii|TrEMBL
MTTHRLPDNRVPVLLSAHEEELIGQDAAAILDYLEYLGTQPGTDDVTPAVAATLLRTRRV
RRHRAVVRAADRTELEAGLRALAAGEQHPLVARSSENAKTRTAFAFPGQGNQWPSMGAVA
YQRLPAYRTEADRCAQAFVAAGLPSPLPYLLGEAPAVLGEVSAGSWAGSSADTSAGSDQG
WSQIDIQGAQFTHAASLAQLWRSCGVLPDLTIGHSLGEAAAAYVAGTITLADAVAVVAAR
ATVVSRLSGRYGMAVLSMDADQAERLITETPGWLELSAVNSPSSSVVSGDRDAVAAIVGR
AEKNGIFARELTVDYPGHTSKLESLRDTLSELLPASQFFDAPVEFVSSACGDVVTPGTDF
TDYWYQNLRNTVRFDQAAATAGQRGASTFVELSAHPSLRYALAELAEDALIVGSGRRDEP
VVEHLSANIAAAAVANPGYRWRDIAGVGDQPLLRGFPTAPMRAIHLWATREPLPPAPGST
LVVAYERWEQLPAHDPRQHNAADRPASAVAIVTLDSADDPLARRLTEAVGAHPACDLTGP
AEAEIAVIIAPAVMQLDAIAAAGRLRSDARQFDYHHAVGARCRRVWLVTICGEQVDAGGP
AALPAQAALAAMHRSVGFEFPDQTFAHLDVPSRDIDEATARQCIDVLLDDHTEVAVRAHD
SGTGLDCFVRTLRESAESAPEGVDAKALDHVVITGGNGTIGLRYARHCVEHGARRVTLLS
RNGVDRDELDRLTAGYPAQVHAPACDITDAEAVSAVAGEYAGDGASLLIHAAGAARFAPH
DQLGDQEWADVFSAKVTGLIRMTDAWPLRPDARILVCSSVSGVWGGYGHAGYAASNRMLD
TVAGRLRGNGLNCMSVRWGLWQGTTIAGADDVARIERSGLIAMDPDAAITTSLGCRQGDP
LILAADFDRLRVFFESQGAAMPFTTTATTERDDDSAADSHSPDQRPISELVRTEIATSFS
LDGPAAVDLNVALVDLGADSMLALDLRDRLRRWTGRSVPAARLLGGITGAELIAILQSAP
GADGPAASPEPTAEPGSTANPERRERLRSARD
>A9KUH8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Shewanella baltica (strain OS195)|TrEMBL
MSHTPSVPNSATESKKDKRLNKRLKDMPVAIVGMASIFANSRYLNKFWDLISEKIDAITD
IPDTHWRAEDYYDADKSKADKSYCKRGGFLPEVDFNPMEFGLPPNILELTDTSQLLSLIV
AKEVLADANLPTDYDRDRIGITLGVGGGQKISQSLNSRLQYPVLKKVFKSSGLSDEDSEM
LIKKFQDQYIHWEENSFPGSLGNVIAGRIANRFDFGGMNCVVDAACAGSLAAIRMALTEL
TEGRSDMMITGGVCTDNSPSMYMSFSKTPAFTTNETIQPFDIDSKGMMIGEGIGMVALKR
LEDAERDGDRIYAVIKGVGASSDGKFKSIYAPRPEGQAKALERAYDDAGFAPHSIGLVEA
HGTGTAAGDVAEFNGLKSVFAQGNDTNQHIALGSVKSQVGHTKSTAGTAGVIKAALALHH
KVLPATINVSQPNPKLNIESSPFYLNTETRPWFQRADATPRRAGVSSFGFGGTNFHLVLE
EYKPEHSRDEQYRQRSVPQTLLFAAANKAALLSELKAALSQSVNTNANKSSAASLNAIAQ
QYPLRTLASTDARLGFVAKDIAQLQAQLNQSIAHLETNAIEVWQLPSGISYRSHALVAKN
ESKKVAALFAGQGSQYLNMGRELACHFPEMRQQVMASDKVFAHHGQTPLSNILYPIPAFD
ADAVKAQEAALTNTLFAQSAIGAISMAQYSLLTQAGFAPDMVAGHSFGELSALCAAGVIS
NEDYVELAFARGHAMAQVPSDTASKAADTGTQTDLGTMFAIILKQKNDIDALNSCLAQFD
GVKIANYNAPTQLVIAGGTEQTQLAAKAISELGFKAIALPVSGAFHTPLVGHAQKPFAKA
IDKAKFSAPSVALYANGTGQLHPSDGKAIKAEFKQHMLQSVRFSEQLQAMYDAGARVFVE
FGPKNILQKLVENTLGEHLNELCLVSMNPNPKGDSDSQLRLAAVQLAVVGVALTEIDPYQ
AITSQEIAEREAPSAMNIKLTATNHISAATKAKMAKSLATGSVTSQVQYVDRIVETVVEK
EVEKIVEKEVIVEKVVEKIIEVEANQVAAVEIKQTSPSVAQGLSNHQQQATAQLSPNTPN
ISSDALTAFFSAQSQAAQLHQQFLAIPQQYGDTFTTLMTEQAKMASQGIAIPESLQRSMG
MFHQHQAQTLQSHAEFMQLQSSSSQAALAMLNNAPINFTPAIASKPRATAPAPAPVAPAP
VATSTVAHNAAPVAAQAVATRPAINTPVAPVVQSAPVAHAPAMTVQVAPAAPALVMPAVV
MPEVTPVAPATSGLSAALVQQTMMAVVADKTGYPTEMLELGMDMEADLGIDSIKRVEILG
TVQDELPGLPELSPEDLAECRTLGEIVDYMNSKLPAAGQVVTSTTAPTAPAANGLSAALV
QQTMMAVVADKTGYPTEMLELSMDMEADLGIDSIKRVEILGTVQDELPGLPELSPEDLAE
CRTLGEIVDYMNSKLPVVSVVAVAPPANVEATPAQVPANNGLSAALVQQTMMAVVADKTG
YPTEMLELGMDMEADLGIDSIKRVEILGTVQDELPGLPELSPEDLAECRTLGEIVNYMNS
KLPAVGSVIVATHVTTAAPAASGLSAALVQQTMMAVVADKTGYPTEMLELSMDMEADLGI
DSIKRVEILGTVQDELPGLPELNPEDLAECRTLGEIVDYMNSKLPVVSAVAVAPAANVEA
TPAQVPANNGLSAEKVQQTMMSVVADKTGYPTEMLELSMDMEADLGIDSIKRVEILGTVQ
DELPGLPELNPDDLAECRTLGEIVSYMQSKLGQNAVSQNVAPISAVVQPEPTIDLPPHDL
PPHSEVVLKKLPAAAELTQLSAQKALPRVFAKDACIIISDDGHNAGVLAEKLHAQGLTVA
VVRSPESLVASASPLNSHIASFTLAAIDDASISAVINEIKSLGQVAGFIHLQPQHKTSAD
AKGLVLSSAAKASVEQAFLFAKHLQPLLTTAATVNTSSSFISVSRIDGGFGYLNHSQIAR
SELNQAALAGLTKTLSHEWPSVHCRALDIAPALDAKQLANAVIAELFATDKLLEVGVSEA
GATDTLARVTLVAGKADTRHGAANLTSADKILVTGGAKGVTFECALSLAKRSKAHFILAG
RSSQQTIPTWAQGKNNSELKAAAIAHIQSLGEKPTPKQVDALVWPVQSSLEIAAALQAFT
AVGASAEYLSLDVNNPDAIASTIVPITELSPITGIIHGAGVLADKHIQDKTLDELARVYG
TKVTGISNLLAALDLDKVKLIALFSSAAGFYGNTGQSDYAMSNDILNKAALQLAQQLPNA
KVMSFDWGPWDGGMVNPALKKMFIDRGVYVIPLKAGAELFASQLLSNTGAQLLVGTDMQG
SAPHDDKPNEVQETEGSNLKKPEADLTTDSSGPHALPNAVKLQRTLDPKAMIFIEDHCIN
GNPVLPTVCAIQWMREAAFDVLKQPVKVQSYKLLKGIIFDTAVLQNGALESAAPITLELE
LAPIALTDKAAKDTDEYLSGQFSALISFEGRPQYQAILVIDDAPSDNLAINSKATAFDAH
SLAGLSAITTASSLYSDGTLFHGPRLQGIESVVKFDDTSLVAKVSLPHVALADCGSFVPN
LAPKGSQAFAEDLLLQAMLVWARLKYGAASLPSSIGEFISHAPFAFGDTGYLVLEVVKHS
GRALEANIALYHQDGRLSCEMNNAKVTISKNLNGAFLANKVANKSIESVEAKVE
>A0A448IW97|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium aurum|TrEMBL
MTPVTLPDGRAAVMLSSHDEGLIAADARAVLSYVEREQCDVTHVGAHVAATRRVRRHRVA
VRAADRDELAAGLRAVIDGTEHPLIAASARRAGTRTAFVFPGQGGQWPSMGAEAYRLLPV
YRAEADRLDAAVQAAGLPSGLPFLTAGGDAHAASQLELQGAQFIHAVALAAVWRSCGVLP
DLTIGHSLGEIAAAYVAGTIGVGDAVAVLAARAYAVDTIAGGYRLAVLGLDADSAADLIA
ATPGWLELSAINASSSVVVAGDTAAITALVAAVEQRGQFVRELAVNFPAHTSALEPLRDD
MLHRLPRSAFVDSAVQFFGSATGGVVPVGTDFGRYWYANLRNTIRFDQAVRSALAGGAET
FIEMSAHPALLFAVTDGADEAARDGRDPAVIVGSGRRDLPLTDCLSANIVAAAVADPGYR
WADLAAPRTRALRGFPSTPMRSTHLWATAEPLPPVGGLTVAAETWQRVTPQDHGSGARRS
VAVLGVAAEAVRGAIASRDDVLIGEPADAETLVVVAPSFPIGGAAAVADLAHRIDTGLLN
YVDAIGPRCRDVWLVTSGAERVRSGEAPADPGQAGLAAMHRCIAFEHPDQRFHHLDLPPT
SPADAGLAPAIVTAILGEAGEIALRDGGAAMYRRALTDDTSSVAAWPLDAGLLDNVVITG
GSGAVGVAFARQLTVRGAKRIVLLSRRGLEPSVLEELRAVGTAEITAPRCDITDRSQLSA
VAAELSAGGATLIIHAAGSAALVDRSGTRGSTLLDNATAKIAGLEHLVHVWPIRVEARIL
LCSSVTGVWGGKEVAAYAAANRMLDVMADHLRFVGRRCVAVRFGLWEGSRIIDAAEIGRA
ERMGMRQMKPEQAVEAGMHDHGHDPVVLAADPGRLRAFFDAAQSAQPEAQTAAPVTAGAA
DAVRSQLAVVLDVDAATLDLDSSLFDLGVDSLLALDLRNRLTRLTGRTVALAALLGGITA
ADLITELDTPHVPEKVDSSRD
>A0A485CSI8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Raoultella planticola|TrEMBL
MGISVGEFAAAVVCGHYTIEQVMPLVCRRGALMQQCASGAMVAVFADEDTLMPLARQFEL
DLAANNGTQHTVFSGPEARLAVFCATLSQHDINYRRLSVTGAAHSALLEPILDRFQDACA
GLHAEPGQIPIISTLTADVIDESTLNQADYWRRTHAPAGAFYPEYSGGASARRPRFSGDG
PDAQLVACGQREYRDNAYWIASARRNKEASDVLNQACSSFTLPASPYRGPTCWRAMVNVS
LRHVIRLILSVTGKSASPRPASLPTQRCLPGWRWRVAPRQRSISLAWKRLNSAPRDCTPS
TSINWYNAVPAMPLRTAWTP
>A0A2N9B6F5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces chartreusis NRRL 3882|TrEMBL
MQQGGMPDIAIVGMGCRFPGARGVRAFWRLLEDNTDAVTPVPEDRFDVRRYYSARPGEPG
TTVSRHGGFIDDLYGFDAAFFGIAPREALAMDPQQRVLLQVVWEALEDAHILPSSLAGSR
TGVFVGQATAEYGDLAESDGHQDVHGMAGSRLRTITAGRLSFALDLRGPSLVVDTACSSS
LVAVHLARQSLLTGESDLAVAAGVNAVLSPSDAITYSRGGMLAPGGRCKFADASGDGFVR
SEGVGAVLLKRLPDALRDGDQVLAVLRGSAVTNDGQGSGTLLQPAVSGQTEMIRSACRSA
GITPAQFDYVEAHGTGTPVGDDVELRALAAALGDERRPGSRPLPIGSVKTNIGHAEAAAG
IAGLIKTVLIARHRTIPASLHLRTPHPVLAGDAAALACVTRNTSLVPGGPAALMGVSSFG
LSGTNAHVIVGEYVPEPRTAQLSHGASDVPGGPQLLLLSARTPAALSGLAARYAGFLEGA
EGRAFTLRDICHTAATRRDAHPHRLWAVGRTHDELAAALRALAAGEETPDGGTADAGFAG
DRRTAFVFPGQGSQWLGMGRRLLACEAVFRRTLTECDAAVREELGWSVIGLLTGDGEDTP
PQELPDDVAVVQPLLWAVQVSLAALLRAKGVEPDLGIGHSMGEVATAQVCGALSLKDAAS
VICRRSSLMQRLAGRGAMLAVELDALSAADAAAPYGDAVCVAAENAPGSTVLAGDAHALH
LVAERLQAEGVSCRPVKVNVASHSPYMTELRDDLADALAHVTPSPARTAMFSTTRCEPVD
GPELDAAYWVDNLCERVRFVEAVRVAAKEETVFLEVGPHPLLVQSVTAVLDEQGAAPAAV
ATLKRHQDDGENITRALGQLFSHGGRIDWNRFFQGTAPRVPLPTYAWDQEQFRREPAAVP
APAAASATPAEHVREVGLRELGLDDLGESVRTRGGAAVVPPVLYVEAVLRAADDIAPGGA
GVLEDVEFGTRPWELAQARDAAVRVSLAPAAQRGCFVFTVTTLRTVDGTRDGELCMTGRY
RTAGQSAVAGPHGRELLDAGLTRCTGYVPAAEFYRRAQGRGYTVDAALRTVAQLWCAEGE
SVARMRRSPGAGTAGLEAGLLTMLATWPHFTGAGGEADGYVPVSFGRVQVQDAAGVGRDH
WCVARFTPSDGTDDARCDVWLTGEDGGPIAEFRDVRLRRRAVGPAHEARAAQAPVPAPPA
ATPEHAPTPDDVLKQAATVLGLSATRLDPRRPLRTLGLDSLLAAELRVRLHRTAGVDIPA
TRLLGREPIGVIAASVASPS
>R9P298|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudozyma hubeiensis (strain SY62)|TrEMBL
MPFFISSRFSPVPCFAAYASQRFHCRPLWVFTGRHTDPRIVPTTATPYWSELIAKLIKRS
RATPRFRHICCAGREAEPESENCLFFAIGPASIALPMDERSKWTSNLAALS
>A0A0U0ZRK1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus|TrEMBL
MLRREASALLAYVAEHPRIAPNRIAGMIFRTRVARRYRALVTVENHDQLVAALRTVVAGT
EHPLVVRNSEPATARRHGFVFPGQGGQRPGMGRLFYDAFPSFRAEVERCADLFAKQFGRS
PLSYLLDDQLPPNDSATVVQPALFTQMAGLAALWRTVGVIPRAVVGHSQGEIAGAYVSGV
MSLDDAVTVVGTRAGIADKFPADDYAMAVIATDRDTCEELLARNSGWAELSVVNSPSMVG
ISGQRETVHQIVEHLTEDGVFARVIPVRYPAHTSMIASIGAQIRRALTENLHAGEFTVSE
IDCIGATLGTAISPEMPVDQYWFWNLRNAVRFDRAVATAAAAHVDTFVELAEHPTLQLAL
RENLAALGSERTACVVSTSRRNATDLAEFTANLAKIAVHDLDYNWDALRAEAPDRVSLPL
RDFPNVQNNDIPLWLSYRTDTSGVAVPKQPAVTPEAERRVDTGNDSRAYPRLLREAWTKM
TRRSMMPPRSYAFIDGTGDAGALVEALRDNAPNFGSSARIVTGTNESGTGDADTVVIVLP
SPALLDDREAAEAVARFFGNRTWWPGLSSTVTGCWLVTVGGEQAVADDRPAHPVHAAIAA
GFRCMGTEHPGIAFRHLDLTPDIAGPDKADNILAALQSAGESELALRADGMYAKRVLDID
QDGDESSRAVAPDHVVITGGTGKLGQEFCEHYARMGTRQITLISRSGETDAVTGRLDAIR
RSTGAKVRALPCDVTDTAAVTALADQLRDTPADLIIHAAVDYSDIPLAEVTVDKFQDALR
AKVIGISNVLDTVPRTDSCRVMLCSSLAATIGGKGQLMYAAGNRMLDVLASARRASGLDC
TSIQWGQWTVHLDLGDTGIAKLAAAGVHPMRPADALAVGMGRHHGNTLVGAFDLTRARAM
LGVFGYGPLLSELEDNSGPVAPAETIRPAPVVPENRSGHLVQLLAEVIGADHADSIDTAM
PMVAMGLDSLQALEFRRRVQAELDFELPVQDLLGGASVDHVIDALTAQSR
>A0A073CRH4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Planktothrix agardhii NIVA-CYA 126/8|TrEMBL
MRGFQKVYPVIFFMTTNQQNSQLNCHEIAEVLLSNPLIEDCYLLVRDSELVAYIVYSGTG
KLEQLSSNVGSKLPDHLLPTLYVQVSNLPLTNTGCVDELALKNIEIIDENLVNNTEKKLQ
SLSGIEQVAVVITSQKYKNLPLHLSELLPLKQPEIVEKQNQEIETQIILPIHASNAQQAI
SHGQPLVESVLQPKTLGDLIQKTAENYPNRGIIYIQSNGSQIFQSYQQLWEQAQRIQTGL
QKLGLQNQDKVIFQLSENYDIISAFWGCILGGFIPVILSVPPTYKEINHEINKICQVWEL
LEQPLIITNESRQQDVKKLEKWLSNQPIKLSFIEELKTYSPHHSHISQPDDIAFFNLTSG
STGMSKCISLTHKNIISRARGANIICEYNNDDIILNWLPFDHIGSISELHIRCVDLGCQM
VYVQTEYILGRPLNWLDLIHQYRITHSWAPNFAYNLINEALKKEPSQTWNLDSIKFFLVA
GEAVSDQVVGEFTNKLHSEYKLKTTAIRPAFGMAEMGSGITYYQPTTEQPLLFHTVDKYS
LTHALKRVHPEHPNSTTFTDLGLPIPGVSIRIVDQENSLLPEEMIGHLQVKGDPVSPGYY
KNPEANQEAFLKDGWFKTGDLGFISNGHLVITGRSKEMIIINGVNYYSHEIETVVEAIEE
VAASYTAACAVHDAKSGTDQLALFFSVEIDQQDLPELLKKIRRKVINSFGVNPEYLIPLN
KNEIPKTSIGKIQRSQLTKRFEAGEFNPVLKQIDILLENANTIPDWFYRKVWKSKSPVNL
KSELSNNYTLIFLDQLGLGEFLAAQIKVKNLPFVTVLAGEEFSKLSGDRYTIKPGEAEHY
QHLMESLAEQKITIGNIIHLWTYQEYQGEIDRIEQLEQAQEQGIYSLLFLVQALAKIHDL
NQTIQLLFVSSHSQCITSIDEIAYEKSPVLGLIKTLAQEIPWLNSRHLDLPIDKNEINGA
YLLQELYVLSKEREIAYREGNRFISGLEKVNLPEQLKQELPFKSGGIYIITGGLGGIGIQ
VAQYLLKNYQARLLLIGKTALPEKHLWNDHLEKEDEFSLKIKNIQALEHLGGEVIYQAVD
VANFTQVQQAVDEVKQHWKGELDGVIHLAGIYKNCLLLDETKQGLAAILRPKVLGTWILH
QLLKESQGIGIFISFSSLASFFGWAALGSYAAANTFLEHLNNYQKSKHLFPSYCYSWTTW
QETGMSKGYQMQYLTRSQGYYDMTVQQGLDSFLASLYHNQGQLMIGLDGSNSKIKRSTSL
SEGLQKLTAYYIPKSPPNPIHLGDHLILKDRFGTPYNCSLIPRQSLPLKDQGEIDKQQLI
KELQGQENREWIAPRTEAEGKVAQIWQNVLNLPQIGIHDNFFELGGHSLLASQVISRLRD
VFSVELSLHSLLEYPTVASLTQTLEVLNVAKNSHSAMTKTPENYEEGEL
>A0A073CFT1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Planktothrix agardhii NIVA-CYA 126/8|TrEMBL
MFKHSISSGGQLKDNWRTLSAVLANAAKYENQGITYIGNDVTEYFQTYQDLYNDALNILD
GLDQRGIKLGDKVILQIAKNKDFIPALWACFLGGIIPVPLTVAPHYELENSAVKKLENVW
KILEQPLILSDNELITEIQKLETQSHLKGLQVVSIDYLRSIESQSNSQPDKTSKKCYSLP
DLTPENQALLLFTSGSTGMPKGVMLTHNNLLSMSAGTVAMNNFSQQEVTLNWMPLDHAGA
IVFLGIMAVDLACDQIHVPMELILRQPLKWLELIQNHQATISWAPNFAFSLINQQSEQLN
QSSYNLSSMKFLVNAGEQVSIKTIRLFLEILEKHQLPDRAIKPAFGMTESCSGITWSVGL
SQDKLTEENIIISLGKPIPGATIRIVDQENNVLPEAEIGRLQIKGKSVTKEYYHNPELNQ
EVFQDEGWFTTGDLAYLLDGELFITGREKQEIIINGINYFAHEIETVIEELEGVNVSYTA
AFALFDQIQETDLLIIIFSPESEHFEQWVKVVRKIRSHLTQKVGIAPAYVIPLETNLVPK
TSIGKVQKSKLKKDFEQGLFAGRIQEINQYLESDRQKNRSLPQSENERQIATVWCEVLQL
TSVGLNDNFFELGGHSLHLIRVHNQLEKLFNRQLPIAEMFKNSTVATLARFLSKESNSTP
ATQQKSRQRAENRSRRQQETHDIAIIGMAGRFPGANNLTTFWENLQNGVETISFFTEEEL
LESGVSPELFNQPNYIRARPIIDQVEYFDSEFFGYTNREAELLDPQQRLFLQSSWECLEN
AGYNPNSYQGAIGIFAGASMNTYLINNCYPNRGQLDSNDELQPFTLDSMGGFQTMVANDK
DYLTTRISYKLNLRGPSINIQTACSTGLVVVHLACQSLINGESDMALAGAASINSPQKIG
YLYQEGLILSNDGHCRAFDSQAQGTIFGSGVGVVLLKRLPDALADNDQIYAVIKGSAINN
DGGTKLGFTAPGGEGQISVAAEALAFAGVDANTISFIEAHGTGTTLGDPIEVDALAKAYG
AANQGECALGSVKTNIGHMQIASGIVGLIKATLALKHQIIPPTLHFQNPNPQIDFSKTPF
YINTEAIPWKTKQQNGQELPRRAGVNSLGIGGVNAHIILEEAPTIIPQQNQTKRPINLLT
ISARTPQALKDLANSYVEFWENHPESDISDVVFTANTGRVHFSNRLAVIGSENSDFITKL
RQFGQLDQGLIIQGQVDEKQPPKIAFLFTGQGSQYAGMAHQLYQTQPTFRQTLEQGESIY
QKLTGKSLLEIIFANSDEILTQTSYTQPALFIIEVALAQLWQSWGIEPIAILGHSLGEYA
AACFAGVFDLESGLKLVINRGRLIGQFPDNQGAMAAIFLDQKSVLEQCQNQGIKIAIAAI
NTDQHTVISGDKKSIQQLCEHFNNTGIKVRQLKVSHAFHSPLIEPICEQFKTILQEITFA
QPQIPLISNLTGEIADDSIITPEYWLQHLLHTVQFHQGVLSLQSLGCDTFIEIGPQPILL
GIIQSSISSSNPLILPSLRSGFSDWEVLLESLGKLYVRGLDIDWFSFNKDYHCSRCSLPT
YPFQQSRHWIPLKTQLPTVTQESSLVKMLSNKNTKSLMQTLLETGNYSETEKQTVSAIVQ
QLIQLHHQQTNNFDFENLLYQVKWFPDNLATQKSENLATIQADLDVYMEKQIQFASLTGV
SLAFAEMEKLSVDFIIKALKDLELFQLNTLLSPDDSFSQAGIKAEYKLLWNHCFKILAET
GILEKQDSGWKIINKPQQSHPDLTVENLINQYPNALIELTLFQRVAANLAAILTGKIAPL
SILFSQNEKIGAAEFYKNTSWAKVLNLSISKAVELLLSNYSPSEPLRILEIGAGTGATTH
QVLNACKSDQINYTFTDVSPFFLETARENFTQFPNINYQVLDIEKDPKSQGFSLNSYDLI
IAANVLHSTRDLQAETLPHIQSLLRPGGQLLLLELTHQSKWIDLIFGITQGWWRFSDDHL
RSHHPIISASTWQSILLKSGFAQAEFVSPDQKIGSALFQQSIIIAQNPRQASNISENWLI
FTDSHPEKDHLPRFIQAQLSKNYGSCTIIYQGQNKIKLSQFEYSLNAHQPEQIKAWFAEN
PSPHRIIYLLNDNHQDQPESILLNRCHYLLNLLQAIQKIPNSPKLFVVTQGGQPFELKQP
TFVTQSPLWALGRVISLENPELWGGMIDLDPSADITQNIADLLLGLTHSISEDHLLFRNG
QAYLGRLVPSTSPPTKPLTIQAEATYLITGGIGHLGLALAGHLVDLGAKHLILTTRRPFP
PSSEISTEFAKIMENLRILEQKGVSVEVCQADVGDFEQIQAIWAKIEKTAYPLRGVFHLA
GVSGRQAQLSECTFADLEIVFQAKVRGSWNLHRLSLATKLDYFVLFSSAGAIWGAKAQGL
YDAVSNSMDSLALMRHLQGLPATTLNWALLAGNGIVSPDYEDWLKQIGMKEIDLDRAFSV
MDAIIESNQTQILVADVDWVRFKNIYEFQGDKPLLKKLGQSQNIIKSVQDSSSTRRLLED
IAPGERREHLFQYIGKQVGMILGIKQMPDPEQGFSEMGIDSLLSIELKNRLEKGLEVTLP
ASLVFDFPNIRRLVDYLIQQVLGWQVQTIVQTTVDSTEVQQDVDADLILRELSELEDFLS
D
>A0A073CT05|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Planktothrix agardhii NIVA-CYA 126/8|TrEMBL
MVQNTDYKKLIATTLTKMEVMQARITELETGQREPIAVVGMGCRFPGGITSPEEYWNYCQ
AGLDAITEVPKSRWDSSKFYAKEPTPGKINTAYCGFIQQDITEFDARFFSISSREATSMD
PQQRLLLEVTWEALENANLPPNNLANNTVGVFVGITSVDNAITVYNSSYDQIDSFFGTGN
ALSAAAGRLSYFFNLRGPCLSIDAACASSLVAVHQAIRSLRNRECEVALVAGVNLILNPA
ITINLSQSGMLSPDGRCKTFDASANGYGRGEGCGVLVLKTLSEAQKKGDRILAILRGSAV
NHNGAAAGLTVPSGPAQQELLRQAIADARITPEDVGYIEAHGTGTSLGDPIEMNAIASVY
GKRSQPLYVGSVKTNIGHLEAAAGMAGIIKTILVLQKGEIPAHLHFQTPNPLINWQDNSI
KIPTQTIPWPNSNKIPMAGVSSFGFSGTNAHVIVEKAPDIKITEIKQPLPSHLLTISAHN
KTALQELARRFSTRLESDPEIGDICYSVAVGRAKLSERLAIVANTLPELQQRLVAFADQN
PLDNLTFYQRFTEEKQPKVVFLFTGQGACYPGMGDQLYQTEPTFRQYIDQCAEILASYLE
YPLPEILFGKHTDLLNQTAYAQPAIFALEYAVAMLWKSWGITPSLLIGHSVGEYVAACIA
GVFSLEAGLALIVKRGQLMQTTKIGKMASIFADEATVISLIQNYSNTVAIAAINHPQQIV
ISGESASIEEIIINCKQQKIAAQYLSVTQAFHSPLMESILNEFEQEAGQISYHRPQILLL
SGIDGKILENAPDASYWRQQCRQPVQFLASLNTALNKGYNLFLEVGSRPILAEQGRRYQD
GAIWLSSLNRGLDNWQTILSALGQLYLNGVYFNPEKFNQNYGYKQVRLPNYPFQRKRFQF
QPNIVEETTQITEIYPEPETNKITELKVQNMQKHQLEIRQQLKSILALLLKENQNDIRDD
ETLLNLGADSIILTDFSRKVEEKFKVKVKIDQLFTDLQTIADIAEYIYNSIEPKNLEPSS
EKTKLNQAEIVNFDPEINNYIEVISQLQPIATAYIIKALETLGKKLNPGETWTTESIKQT
LPIAPKYQVLVTRYLQDLEQANIIQNQGNIWTVKNLPASFSLPEAIENLQKTCPSAKPEL
EMLQRCGENLAEVLKGNIDPLTLIFPEGSVTHAESIYGNSPVSRLMNQRVAEAINLTLNN
FSPSINPYKIIEIGGGTGATSETILNNLNLNRVSYSFSELSPFLLNQARQKFQSKYNLNF
HQLDIEKSPISQGISSHSYHIVVAANVLHATQNITETLTNIRELLLPGGYLILLETVENN
SWLNLTFGLTPGWWRFQDKELRSDTPLLSGESWCSVLKRCGFATANSFSKQNNISIYNGQ
ELIIACAAAEILPIPQTPKATQFQAVTSGKEALMMAQLQSLKDLKDLHEKTIIKQLEILQ
SVGITPNIITEKPIIQTEIIPSQNYQIETVSPAQREQTKLPQKPSSPSLNPLALKLNESK
SLTEKQQDFINNLQTIYNQKTAKSKAYSQNSRQTMVDVKPTIDFRMTLKEFQYPIVSESA
QGACFRDIDGNDYIDLAMGFGVNFFGHSPDFVIAAVQEQMQQGIGLGMQSNLAAETAALI
SEMAGVERVAFSNTGTEAIMAAVRIARSRTKRPKIVIFSGSYHGTFDGILARVGEDSTSI
PVSLGTPSGMVEDVIVLSYGVEESLEIIAAHSDDLAAVLVEPVQSRKPDLQPQEFLQKLR
KLTQEKGIALIFDEIITGFRIAPGGAQQWFNIEADIVIYGKAIGGGLPISMICGKADFLD
TVDGGFWKYGDDSHPQTELTAFGGTFCRHPLALAACRAVLLYLKEQSPTIQERVNQLTQR
LATEVNQFFQEIGIPIRIVNFGSLFRFEPFGAYSLFLQPIELPLFYYLLNLKGIYTWEKR
VCFLSTCHTNEDIDKVIATVKSAIIELQQGGFFENAKLLKVNKQDKNVEREDEDGRENLN
PINQQFPTSEAQRQLWLLAELDRNASASYNVTASLELRGSLDISALQEAINQVINRHESL
RTQILEQGEVQEVINSVKIQLTLINLNDEQNPQAMALGLRSQFSKKPFDLSIAPLFDVIL
IRLNSDHYLLSLKTHHIVVDGWSLGLILNEIGQLYSTQIGATTDPLEFPMQFRQYLALRE
QEAQSPQMLEHRDFWLKTYQGEIPAFELPTDFPRPAIKTYTGGQESKIVTPELWQNLQTV
GRQNQATLFMTMFAAYTAFLSRISGHNDLVIGIPISGRQIEGSDQLVGFCSQFLPIRIKV
DITHSFVEHLQRTKQTLIAAFRHQSYTLEDLLAALQLQRDFSRSPLISVSFNIDPSLTLP
DFEGLKVSLPPEPIGYTPFDVGFNFIEVNNNLIIYCNYNTELFKQETIKQFLESFEILLD
GVINNANSWLHQLPLLTKLQRENLLAELIGETRELPENATIIDDFVSQVNSTPNAPALVC
GETTLTYQELNQKVNRLTHYLQHQYQLGAGKIMGLMMGRNQNLIISILAIFKTGATYVPI
DAEYPNNRIDFIIKDSGCHVCLTESNLISKLPQEIETICLDKIDNILAKYGNQEPNIPPD
SSQIAYIFYTSGSTGNPKGVMGRHLSILNVIQSLRLTFNLDKYPEWRYIFTAAVTHDPSI
RNIFLPLTIGAPLYIYEVKYIGHLVSFLQENQINALHTTPSIYREILALLEPGETISSLK
YISVGGEKLDRETALALRQLFPGEIVSNVYGSTETCVGVSQYKINENLDTDVPLGQVFHN
NRLFLLDEFNNPVPLHIVGEICVEGAALASGYHNLPQITKEKFKPGFFDQKTTMFRTGDL
GKQTAPGVIEFMGRKDNQVKVNGYRIDPEEIEYQLNRYPQIERAIILPISVNNQTQLSAY
CQTDKQIEISEIREFLANFLPVYMIPSYFIFLKQFPLTKHGKLDLNSMIALNETGKSTQV
NYVAPRNNLESNLVRIWEKILTKHPIGIFDNFFEIGGHSLMLSRIVTHVHKELNVSVKLA
DFFKVPTIAGLAVLVSKTEYDYQEPIPTIPLQKSYPMSHGQRRLWALEFLDQNHNAYGMP
SVYQFNGNLNIAAFENAFQQLIQRHEILRTTFSLIDNQPRQVVHNQMNFGIKQIDLTNYL
ETEQAKLIAEAISHNAKTTFDLEVGPLLRVNLLKLSQENYIVLFNMHHIISDGWSAGVLI
KDFLGHYHTYRQQNSELLPPLKIHYKDYTDWQENQLKTSKLQAQRDYWLTKLTPAPQHLN
LPFDYPRPAVQSFQGNTVIWKPNSELIEHFQILIKDKEASLFMGLLTLVKSFLFRYTEQN
EITVGSPIAGRNHPDLESQIGFYVNTLVLRDQIRADDSFLNVLTTVKTTTLEAYENQEYP
FDKIVSDLNLPRDPSRNTLFDVAVALQNNQNVDLALEGITVNSIDPEMTTAKFDLEFIFV
EEGELYLKLIYNTDIFINERILLMINLLENLMEQVIKYPDKPLIKLSLESSNFGQEYSDL
FAEDFNF
>A0A4U9HFJ3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Serratia rubidaea|TrEMBL
MKQRVIASGWGQCSPLAADVPTLIEAIAAGRCATSAPWFDNDDDWQNLRLGNNPHTARAA
RADAAPWQQLQPVIDEALTMAGLSASALQGPRVRVFLAGNGMRPNIADFAGYQDRNDAED
LLFFPAIKQLHADSYAQDALARRFVETYRLDWPPTSVYSASNSSLTALHLAQAGIAAGQT
DVALVAGWLKIVLQDVVFMGGQDMLGNGQSQPFNNQDNSVLLADGAVALVIESEEHARRR
GVTRRSPSAVQCAARAAAAAAAPLPPISAPLRKTIDGALQAAGLTPQDIACALPHANGTV
AGDKAEAMALQKVWGRNGIPVVSYKGQAGYVATCSGVLDFMLAADALLQRRLLAATGRHP
VDAALAIRVHMDAPPLPLRTPHLLKSGIGLDGSVIAMVLSDCREGIDE
>A0A2X2P7L4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces griseus|TrEMBL
MNTFEHASSNAVAVVGLSCRLPGAPDTPSFWRLLSSGTSAITESSRFGDAVPVRWGGFLP
DDEVGAFDAEFFGISPKEAAAMDPQQRLLLELGWEALEDAGYVPAELRGEHLGVFVGSMA
SDYATIAARAGVVSRHSLTGLNRGLLANRLSYVLGLRGPSLAVDTGQSSSLVAVHLACQS
LRSGESEVALAAGVNLILTPQSTVEADRFGALSADGRSFTFDARANGYVRGEGGAVLVLK
GLAAARRDGDTVYAVIRGSAVNNDGPAATLTTPSRSAQEAVITAAHRRAGTAPDEVGYVE
LHGTGTPVGDPIEANALGATLGRGRTEPLRVGSVKTNIGHLEGAAGIAGLLKTVLSLHHG
AVPPSLNFATPNPDVPLEELNLSVQQELEEVGPTVAGVSSFGVGGTNCHVVLTGTERSPR
EPRPAAAGGPLPWVLSARTEQGLRDQAGRLYERVAAPDAPASDDIAFSLATSRTHFPYRA
AVLSGDAEGLLGLRDGGLSADLVRGRAVPSGGTVLVFPGQGSQWAGMAAELIATAPVFAA
KIHACAEVIDPLVGWSLVDVLREEPGSPSLERDDVVQPALFAVMVAFAALWQAAGVRPDA
VIGHSQGEMAAAHVAGALSLRDAATLVVRRAQQVVRIPRAGGLLSVPLPVAKVREDIAAW
PDRLGIGAVNGPSATIVSGELDALRELESAYVADGVKARVVPINYASHSPLVEDIREDVL
RAAADVEPLRTDVAFYSTVTGALLPDTSVLDAEYWYGNLRQAVEFERAVRAAFADGHTTF
VECSAHPVLGVGITQILEGREAVITGTLRRDRGGLRQFLSSLAGVHVGGGAVDWAAADWE
GLLAGRPVRRVALPSYAFQRERQWLDVAADGVVPSVPGPRPAPEQAPAGGGQRPGSGGDL
TPERALDLVRGAVAVVLGHASPASVPVDATFKELGLDSIGAVEFGRALAGATGRPTTSTL
TYDHPTPASVAAYLTRGDAEEEFTAAGASDEPIAIVSASGRWPGGADTPERLWQIAVDGV
DTVGPFPSNRGWDLEALYSPDEPRTGTSYTDRGAFLYGADEFDGAFFGLGPREATAMDPQ
QRLLLESAWEAVERAGIEPGSLRGSPTGVFIGVMPQEYGTRLHQTTEEYDGHALTGGLTA
VASGRLSYVLGLEGPAISVDTACSASLVSMHLAVQSLRRGECDLALAGGVTVMSTPGMFT
EFSRQRGLARDGRCKPFSDAADGTAWGEAAGVVMLERLSDAVRNGHPVLALVRGSAINQD
GASNGLTAPNGPSQERVIRASLADAGLRPSDVDAVEAHGTGTTLGDPIEAQALLATYGRE
RDVPLLLGSVKSNIGHTQAAAGVTGVIKMVHALRNGVLPATLHVDEVSRHVDWSPGTVSV
LTRNTPWPETGRPRRAAVSSFGISGTNAHLILEQAPKTAPASGAVEGAGAAEAAVSAVSA
EAVTGPAVVPWVLSAGSVAALREQAARLHERVLGDPGAGVEDIAASLTRTRSSFDHRAVV
VGAREQLLDGLLAVRDDEEESAAVVRGTVAPRGRTVFVFPGQGAQWAGMGRELLATSPVF
ARAIERCAESLAPHIDWSLTDVLRGEPDSASLERVDVVQPALWAMNVALAELWKSAGVRP
DAVIGHSQGEIAAAVVAGALSVEDGARTVALRSRAIKQIEGGGGMASVPLPADAVRERLT
RWGARLDVAAINGPSATIVSGDADALREMVDACRADGVSAKTIPVSYASHSSHVEAVRDD
LARALKDVEPRATGLTFFSTVTTRPLDTTLLNADYWYENLRETVRFEDTVRAALADGCTT
FVEISPHPVVAVGLNQITDEAVITGTLRRDKGGLDQFYAALARVHVTGVTVAWENVVSGR
TVELPTYPFQRRRFWLDAPATTGDVGAAGLEEAGHPLLGATVELAGDGGLVLTGRVSLGV
HRWLADHAVFGRPLLPGTGFLELALHAAGRVGAASVDELTLEAPLLLTEDGAAQIQVVAG
PADEDGQRTVGVYSREAGGEWTRNAHGTLATAPDGEPAVREERLSGTWPPPDATTVDVEE
LYDRLSAQGYDYGPAFRGLRAVWQRGEEIFAEVALDEDAPGAEEFGLHPALLDAMLHPVV
GIAVTGPQVRLPFSWNGVRLYAPGATELRVRISPAGQDAVTITAATEGGLPVAHVDSLRL
LPVSADQLGGARTTPPYRLTWSETAVTRAPEPAVAVTDIETGFAELADVPEFVVLDVASR
APGSVVAETHRVTARVTELLREWLADERFTASTLVLRTRHAVATGAPADADAVADLVAAP
VWGLVRTAQAEHPDRLVLLDADGDLDAGLLAGAVASGEAQFAIRDGAVLVPRLAQLTPGA
LAGAVPALDPEGTVLITGGTGGLGGLVAKHLVTRHAVRHLVLTSRRGADAPGARELADEL
VALGARVRLAACDAAEADDLAALLATVPPEHPLTAVVHTAGVIADGTVASLSAERVHSVL
RPKVDAAWNLHELTSGLDLSAFVLFSSAVGVVGNPGQANYGAANGFQDSLAHHRHAQGLP
AVSAAWGLWAEASGMTSHMTATDVERIGQRGLRPMPTEVGLAHFDAALSAGLPALVTARI
ETRDVDTGSIPVLKGLAGSGPKRNAPKRSLAAELVGLDAAQQHALLLDAVLRTAAGTLGH
DSADAITAHGGFLEQGFDSLSAVELRTRLGRLVDTKLPSTLTFDYPTPDAIAGHLRSLLV
RDGTESAPDVLGELDRLRALLSATDAEALEKDRVAVVAALNELMGLVDVEYAIDTQRSDE
DFFAMIDNELA
>E3J2B4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia inefficax (strain DSM 45817 / CECT 9037 / EuI1c)|TrEMBL
MTRTSSQRDPVRPTRPGDAATASVPTASTLPAPATAARELVAVVTPFAEPNAALVAAVER
AGGLGVLDLGRDATRARRALADAARWCDAFAVRVGPAAPLRPADLPAGVDTVLLADPDLL
AATRPTGTAEPAEWDVASAAGPAAQRRVLVEVTSVAGARAALAAGADGVVARGSEAGGLV
GDLTTFTLLQHLRAASLTTRSGAPAPFWAAGGIGPHSAAGAVALGAAGVVLDAQLALVRE
VELPAEVASAIRAMDGSETTLLGDHRVYIRPDLPVARLAATPANDPARPRATGETAADLR
DTGGEIASDGTLPAGTGATPSAAEIATRLGAKDLRAQLLPIGQDGAFAGPLADLYVTASG
VVGAVRAAIGDQLATAASLRPLAPGAPFAAARGLRYPLAQGPMTRVSDVPAFAKAVADGG
GLPFLALALLTGEQSRALLTETAELLGDAPWGVGVLGFAPPEVRNAQLEAVLAVRPPCAL
IAGGRPAQATPLEAAGIDTFLHVPSPGLLDRFVADGARKFVFEGRECGGHVGPRASFALW
EAQVAGLLAAGERAGGTFFEELHLLFAGGVHDEASAAAVAAVAAPLAARGAKVGALMGTA
YLFTDEAVTSGAIQAGFQDAALACERTVLLETSPGHATRCVRSPFVDTFLAARADLAAAG
RGRQEMWAELESLNLGRLRIASKGVRRDGGALVTVDPATQAAEGMFMIGQVAALRAERTT
VPALHEQVTTGAGDALARRAAELGLAAAEVPAQAGTDAAHEGTRRDAAARSVAAVRETAR
PLDIAIVGMAAVFPGAPDVETFWANIVSGVDAVTEVPADRFDADRFYAEDAFVKDAGKMT
PSKWGGFLPPIPFDALAYGIPPRSLRSIETGQLLALEVAARALRDAGYDTGIGGQDKAGG
RRRAGRAFDRSRTSVVFGAEAGADLSGAYGLRAGFRALLGDLPAELDDHLPELDEDSFPG
ILANVIAGRVANRLDLGGSNFTVDAACASSFAALDAACKELAAGNADMVLCGGADTHNGL
NDFLMFASVHALSPSGKCASFDSSADGITLGEGVAVVVLKRLADAERDGDRIQAVVRAVA
GSSDGRALGLTAPRRAGQVLSLERAYGRAGVSPSEVGLVEAHATGTVVGDRTELSTLTDV
FSEHGAEPGSITVGSVKSQIGHTKCAAGMAGLIKATRALAAGVRPPTLHVTKPNPAWEAG
SSPFAFERTARPWAAPAAERHAGVSAFGFGGTNFHVVLSAYDGAPEPAHGLGLWPAELFV
VRGADRAAAARRLDRLAELAETNESAGRPWRLRDLARTVADDRSGPVQLAFVVADLDELP
TALARARSFQADPRAGLFVAPDKADQTDRADQTDRADQTDDTAGPGRVGFLFPGQGSQRP
GMLADLFVAFPRLRELLAHGPHLADTMFPPAPFGRAEADAQAAAITDTRAAQPILGLADL
AMADLLGSLGIRADDLAGHSYGELVALTVAGVLDRADLVGLSEARAAAILAAAGDDPGTM
AAVSATAEKTRAALAAAGGLAEQVVLANQNAPKQTVISGTTAAVGAALTALSAAGLTAKQ
IPVAAAFHSPVVAGAAATLADVLAGLDVRPADARVWSNTTGAPYPGTGDEVRATLAGQVA
APVRFVEQVEAMYAAGVRTFVEVGPGRVLTGLVGKILAGRPHRAVATDVAGEPGLRRLLL
AVAELAAAGVPVDVAPLFAGRDAKAVAVADAPRRPGWLVDGAFVRTADGRPVAGGLKPPT
VLSLAAPLVPAATPGSVLLPAEPDASRPVDAAVLEFLRTTRDLVAAQRDVVLGYLGQGGA
RDLGHDGALLDGLGLGSVAPQAFHPGGAQPAGRALAIPAQAVPVEPVAAQAPATASNGVP
AGPVGRGVVLDAVVEVIGSQTGYPAEMLEPGLDLEADLSIDSIKRTEILGELAGRLGLAG
AEGGELDESVVEELAAIKTVDGIVDWIVARAPRTAQPGPDGPAAPAGGPIPAGSVPAGAA
QPPTLAGPPARGLVLDAVVEVIGSQTGYPAEMLEPGLDLEADLSIDSIKRTEILGELAGR
LGLAGAEGGELDESVVEELAAIKTVDGIVDWIVAHGGGSAGAAGSAAAVTPSAGVVPPGA
VPAQPTPARFGTPFQAGPGLSTAPPSRNGSSHNGAAHNGSSGNGLSGGGSSQPGAHVPSR
ADAPPAVATLDAGPRPVGRGVVLDAVVEVIGSQTGYPAEMLEPGLDLEADLSIDSIKRTE
ILGELAGRLGLAGAEGGELDESVVEELAAIKTVDGIVDWIVAHTSAAAAGAAETTPAAAA
ASTRIPLRRFVVEPVPLPAAPSVAEALARLGAARPGGPGPLAGGRFAVVEGGLGVGLELA
DLLEQAGAAVRLLDAGAPDLADQVASGVAADGLLWVAALDAGTGSAAELPGAFAALKAAV
LGPRAAGGGGGTRRLVLASGLGGDFGRRAAAGVDPGPAAGAGFAGLARTLAHELPDVAVR
VVDVDPKDAPRRIAESLLAEMLATDAPLVVGHRDGVRSALRVVPVELAAPVSAGLETAGL
GPDSVVLLTGGARGITALLAVEIARRSGAHVELVGRTPPPAAPEDPATAGALDAPALRRA
LIATGMRKPAEIEARLARLLAEREVRATLAELERTAAGVRYHAVDVRDAAAVRAVVADVY
ARHGRLDGVVHGAGVLEDRLVRDKTPESFARVYSTKVDGARALLGALRRDRCLRETGSAA
PSGPDLGGPGFVVLFGSVAGVFGNRGQVDYAAANDTLDALAHAHAGVFRTYRQTAQPGSA
EPAGVPGRVVSVDWGPWRAEGGGMVSAELEREYARRGIGLIEPAEGVAALLHELSSPQAP
GTQGPAQVVYLCGEADALHG
>A0A655A1Q6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MLLSRRAADQATVAMLRKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVI
SGTAPGVTSAAVVDNFAAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAAN
RLLDVMAAQLRAQGRHCVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAI
EASLHEFTVDPLVFAADAARLQMLLDSRQFERYEGPTDPNLTIVDAVRTQLAAVLGIPQA
GEVNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERSH
TAQKVDISRD
>T2HZW4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Bifidobacterium longum subsp. longum CECT 7347|TrEMBL
MKAVYASTVNHADPLAALAVGEQPEPQARPFWSTVSVRAVTVNHHDVWSLQGVGLAAEQT
PMILGTDAVGVLDEDIPGKHGLKAGSEVVLYTFVGTDGAGVAPGERRTILSEKYPGTMAE
KTAVPSANVFAKPASLTTAEAAALGTSWLTAYSLLFDAAGIKPGDSVLIQGAGGGVSTAA
IQLAHAAGLEVFVTSRDADKRSKALKLGANAALEIGARLPRKVDAVIESVGAATWSHSMK
SVRPGGTIAICGATTGDQPGAELTRLFFQDIRVQGCTMGSREDFARLLRFVEHANLHPAI
DSVVSGLDAAPEAFAKMIAGDVFGKIVIEL
>A0A2P8AMI0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MH33|TrEMBL
MPDAAAVLDGVAEDRGPVTDPARALRDRLAGVPAGDRQRILLDLVRAHAATVLGHAGPGA
VEPDRDFLELGFDSLTALELRDALRQETGAELSATLLFDHPTPIALAGHLLGHLLGAEAG
AVPAAAGAPEGGGGILGGLFREPKARADAAGYAELLVKLAQFRPSFTEPAQLTRPAGILR
LADGPGAPVVCCCTMSLLSGPHEYARLAAGLRGRRDVWALPNPGFGAGEELPADLDALLR
VHADTVLRTVGAGRFVLAGHSGGAMVANVLARELERQGRPPAAVVLMDTYPPGSEVLGGW
TAQLLDGMVERDSAYTPMDDHRATAWAGYLPLFLDWRPAPMESATLLVRASEPLGEWTGE
PDGWRSVWPYPHEARDAAGDHFTMVGERGPELAATVDEWLTARGL
>K9ZH50|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Anabaena cylindrica (strain ATCC 27899 / PCC 7122)|TrEMBL
MISASSINTALSELESLINSCEKDLIRFIEEKQMKSETSISTNKINRQLQQNPIAIVGMA
SLLPKARNLREYWRNIVNKTDCITDVPDTHWSVKDYYDPNPRTPEDKTYCKRGGFIPEVD
FNPMEFGIPPSILEVTDVSQLLSLVVAKEAMEDAGYSESREFNRENVGVILGVAQAKQLG
IPLSARLEYPIWEKVLKSSGLSDEDTKVIVDKIKTAYVKWDENAFPGMLANVVAGRIANR
LNFGGTNCVVDAACASSFGALKMAISELIEYRSDMMLTGGVDTDNTIMAYISFSKTPAVT
PSENVKPFDAKSDGMMLGEGIGMIVLKRLEDAERDGDKIYAVIKGIGTSSDGRYKSIYAP
RKEGQVKALERAYNDAGFSPATVGLMEAHGTGTMAGDPTEFGSLRDFLTQYDNKKQHIAL
GSVKSQIGHTKAAAGAASLIKTALALHHKILPPTINITEPNPKLDIQNSSFYLNTETRPW
IKAEGEAPRRAGVSSFGFGGTNYHVVLEEYEAEQKQAYRLHNAASEMLLFAANPSELINK
LEATFHNLQSNEGERHYSQLIQESQSLTIPQTAARIGFVAESLQEACKLLKVSIDLLKNK
PSAVSWEHPQGIYYRSSGMELGGKVVALFSGQGSQYLEMGREAVMNFPALRRLYGQMDGL
LIKDNLQPISQIVFPNPTFEEEEKTAQIAALQRTEYAQPAIGVFSAGLYSIFQEAGFKSD
FAAGHSFGELTALWAAGVLTEEDYLFLVKSRGQAMAAPKDPDHDAGSMLAVKEDITKVEA
VLRHFPQVAIANFNSPTQVVLAGPTAEIKKIQQKFRELGYGAVLLPVSAAFHTPLIAFAQ
KSFAIATKSVDFQNPKVPVFSNVTGKQYPQEPSGIQRVLEGHLSSSVLFKQEIENIYAAG
GYCFVEFGPKRILTNLVKDILGDRPHLTVSLNPSTQKNSDRSLREAAIQLRVIGMALSNL
DPYQLPPIIPPTATKKTLSVKLNGINYVSEKTRNAFTEALEDGFKIKGVQEIRSLEVQES
KDLEVQHSPLPTPINSHNGNGNGNGHKKTPVNTTPQQPQMIPAPRSNQAIQELLPTTARY
AVAQRPGGKMETPDKNMNFQQVLESLENLLNQFQHNQSDNLQIHGTYLNHQMEYAKTFFQ
LMQQQNALFTNNQTSETAQLKQVVMETFERSMMQFHNQQGETLRIHEQYLQEQVEYTKNF
FQLIQQEYSLLIAGTDTTQPVIPPQLTETHTNSLRELMSPEPTITETVVPPTVKIVETQP
VIEPVVEKAAPVIAAIPTPQIAEPTPVIETQPEPVAPVALIPEPATSNLNIEDIGKNLLA
ITSEKTGYPIEMLELDMDMEADLGIDSIKRVEILGGLQELYPNLPKPNLEELSEKRTIGQ
VVEYLQKQVTDDRLTEEIQVTGDRLQVTEKKVEEAREELPLPSPQSPVPSPQSLVPSNEY
ADLGQTLLNITSEKTGYPVEMLELDMDMEADLGIDSIKRVEILGAMQETYPDLPKPNIEE
LGDLRTIGQIVDYLQKLAGGEKKTPDFNPVEAESPRTLTLPEVAVDLTPPPLVDPNLPRR
PAKLKSLPRPDFWECKLPEGHIALITDDGSLTTTKLAHALIEQNWKVVVLSFPQTLVAEQ
LPLPVGVNRVTLANLSEEHLQLLLQSITAKHGKIGTFIHLHPQFPGENTGKISYLEAEKA
IVKQVFLIAKHLKPTLNAAADLEGRVSFCTVAHLDGAFGLEHKENFGIIGAGLFGLTKSL
RWEWPKVFFRAIDLSPTLDPHQSAEYIVAELHDSNRYIGEVGYSSQGRVTLVAKPE
>K9ZI76|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Anabaena cylindrica (strain ATCC 27899 / PCC 7122)|TrEMBL
MAASKIEAVLSQLQDEISNCEKALLKLIKRKINMSENTNLLSKINTQLQQTNVAIIGMAS
IFPQSKNLQEYWETIIQKIDCITDVPTSRWSIEDYYDPNPHAVDKTYSKRGGFLPDIDFN
PMEFGLPPNILEVTDISQLLGLVVAKAAMKDAGYGESSQINSEIYDRTGVVLGVAIGRQL
AVPLGARLQYPIWEKVLKNSGLSDQDTEKIIQKIKSAYVQWEENAFPGMLANVISGRIAN
RLDLGGMNCVVDAACASSLGALRMAISELVEHRADMMLTGGVDTDNSIFAYMCFSKTPAI
SPGEKVKPFDAESDGMMLGEGVGMLVLKRLEDAVRDSDRIYAVIKGIGSSSDGKYKSIYA
PRSEGQIKALQRAYQEAGISPASVSLIEAHGTGTMVGDPTEFTSIKQFFGENNSKTQHIA
LGTVKSQIGHTKAAAGAASLIKTALALHHKVLPPTINVTKPHPKLNIENSPFYLNTETRP
WISSQPRRAGVSAFGFGGTNYHVVLEEYENEHDQSYRLHNTPKSILLSAPTTPELLSRCQ
EIYQQLKSDQKQLRYQQIITESETLEIPINYNRIGFLVNNCTQAEEFLQLSIDQLKKQPK
AESWEHPKGIYYRQTGIETKGKIVALFSGQGSQYLDMGKEVAVNFPNLRQTYAHMDKLLC
KDGLNPLSEVVFPHPVFDAEQKKHQLEILQKTEYAQPAIGAFSAALYNILKQAGFKADFV
AGHSFGELTALWAGGVLSEEDYFFLVTARGKAMATSPESDPGGMLAVKGDVGQLQELIKN
FPQVAIANWNSPNQVVLAGKKVELAQVQNVLKEKGFLTFLLGVSAAFHTPLVAHAQEPFL
QAIEKVNFNDAKIPIYTNVTGERYPSDSSSIQKILKKHLLNQVLFQQEIENIYADGGYCF
IEFGPKNVLTNLVKDILNDKPHIAVALNGNHAKNSDLVLREAIIQLRVVGLPLQKLDPYQ
IETKITQVDQKKVLNVRLNSTNITDKAKQAFAQAMEDGYQISTVSPHAELMNKNQTSTVS
SFTEVSNEHYQIVEIESLLPAHNELINGNGKSTHNEDNSKLDKVEIPIANYEKVIDGLEQ
SLAEFTRNQRDITQAHEQSLHNQTEYTKTFYQLMQQQHSLLANNQVSEYQAQTQQLAISS
SERSIMRLHDHQTDTIHIHKQYLSYQQEYTHNYFQLLQQHYNFLLVPNDRPQPQNPSRYL
PKEVREGEENEKNLINKNGVNNSSALQEGLQESSNTITVVPTNPIDINISTLGQTLLTIV
SDKTGYPTEMLDLSMDIEADLGIDSIKRVEILGGLLELYPDLPKPNPEELGQLRTLGQIA
EYIKTLIPDLLNQKVEVSEATIVPAQTLVKVPHDTEENQPQIPEAQTNFPELEVSLTPIQ
LLSTSEDKLEEIAANDIDKQIIIPTDLSNILLTIVSDKTGYPTEMLELSMDIEADLGIDS
IKRVEILGGLLELYPNLPRPNPEELGQLRTLGQIAEYMQDLAKGITKLLTEKKQDLKVTE
LNHKILRSPVKLQQLPQPDVLEFNIPENHIALITDNGSSTTGKLATALMEKGWKTVVLSF
PSVQSTLVEGINHVVLNDWSEEGLKQQLEDISCDYGAVGTFIHLHSATHDQASHSVRYLE
TEHTVLRHVFLVAKYLKESLTNAATKGRSCFINVARLDGEFGLGHTINFGVIGAGIFGLT
KSLNQEWEAVFCRSLDLSPDLDVDTSVKYILAELQDPNLLVTEVGYSHKGRVTLIAEPAS
LSISNSPLPITKDQVFLVSGGAKGITAQCVIKLAQQYQCKFILLGRSSTEAEPVWAEGYE
NEAQLKQQIMEDFQARGEKPTPRMVQKKYQAISSQREIQNTLKAIEKAGGEAVYLSVDVT
DGILLEQKLASIVECVGEITGIIHGAGNLADKRIEKKSIHDFETVYSSKVKGLENLLRCV
PPKQLQYLVLFSSVVGFYGNVGQSDYAIANEILNKSAHLVKRNHPDCHVAAINWGPWDSG
MVSPELKQVFTERGIETIPVEIGTQMLVDELTNASPETVQLVIGSPLVYIPSSLSSELKT
YRIHRQLTLAANPFLQDHVILGRPVLPATCGLLWMANTCEQIYPGFKAFSCLNFKVLKGI
VFDENFVDEYTLELQEVAKIENKEIEISAKISSITPEGKIRYHFSTNLILKREIPITPNY
ELLNLNQDEQFLSTNQLLYQNGTSSLFHGTIFQGVKSVLNASPGKLTIKCNLPQPTAQQQ
GQFPVQTFNPYIADVQIHSLWIWTQHFHQIGCLPSEIQNFEQFVQIPFGETFYVTCEIQS
KTESNVVANIITHNKEGQIYNQMIGAKGTILPKQIG
>A0A086JX17|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii p89|TrEMBL
MANAEKLVKLHGLWFRSLWKWAEKIPHEDAVIWLDENGSKAASLTYQKLRREALIIATCL
RQVHCQPGDRAILCYPPSVSFVPAFLGCQICGLTAVPVYPPGSNDRDSDSIQRIVAMVKT
TRPSVVLSSSPLRYFLKEVFPGAAARCVSDIRWIFTDELPDHVEAGSAFELDSLDIKSET
PAFIQFSSGSTGNPKGCVVTHMALLHNIHLNWRMCGAFHPGTEESLYDLPVESYAEFTEK
YQKHLVATWGHRLRSFSWLPVTHDMGLVGMLCVPLFFGCTAFFMSPIDFVRAPHSWLGGM
SKFGCSFTAAPDFAYALAARKVPDDLVLELNFEKILACVNGAEPIRPATIEAFLQKFAPA
GFQPWMMSPAYGLAEHTVGVTGRGSEGRKPMSPKIIEVNNEKVAQGDTVELFKRSGKQEN
EMCTKLIVGCGIPHEDVIVKIVDPRLLQELSEWQVGEVWVSSPSAASGYFGSPVETASTF
NLHLNTADGATRGDRTFLRTGDLGFLGDGELFITGRLKDVVILRGCNYYPQDIEEAVERC
DSVRKGGVMAFSISTTDDAEGLGVAAEIQKGSEKPAKLKLIYADIVRTVNKVLHLPLQRL
WLLRAGSLPKTTSGKPRRSEARRRLLQAERCDDILYSYTRNLSHSGHLPFRPGTFELDME
QKQEDSASTSKSEVNKSLVESLSTAKGARHTDDGFIFTNGQQNLHEAKKDQHGTSDSTLA
EPVSNAILDPITRVTDALLVTADGTSVHKDEEELSLVAECFACVTGVEKSCLRPDTPFLS
LGLDSLTAVELANEIQRRMKQPVEPFELFEFADLRSLALYLRNKKLDHGKDARGRQTKSS
PERSLGIVQVQRPSVFVTGVACALPGSCQTPDKLWEILDAGIDCVGPIPPNRNFCASQNF
AVIGEPRTANASFCVTEGGFLDDVDLFDNSFFGIPDAEAMTMDPQQRLLLMKAVEALHAA
GMATIDSRSAPIATFVGCCSTDWQRMNLGEQIQSFSATSHSASMLSNRLSYTLGLTGASI
TVDTACSSSLTALHCAMQELQHRHVPCHTAVVATVNLLLTTDVTLAFARAGFLSPTYRCK
TFDDAADGFVRSEGVVVFVLQTDVSETPTPNFKNQQEDNEGGQGECGTRIPASGYLCRIL
ASTVVHGGKTGSVTAPSGSSQELLYKQTFACAQVPPRAVDLVETHGTGTRLGDPIEISAL
CNSFAPDMETRKHRLVLGALKTNLGHLEGASGLAGLLKSVLCLNRQRVPPNLHLRKLNRF
IDFRSLPVLLPTKTVPLPASSSETKDAVALVTSLGFGGTYAQVAVQVPSTTGNEMLLRNQ
ETVQWNKKCFDVGKLVSQSNSFQSAVSHNDTKGPCFWEVGWEFLLEFDSITLTLPTLPEQ
APPAKWLVLTSPKAQQSFRKFSVNIFLPGIRMTFACLEELKAPEHLEAILKAETWTAIVS
TYTTETGSCMTDSSDLIGRTLQILQTYGQMASQSAVLPRLLFLTQGCFQVGAAASLLRAS
PYNAGIIGFVRACRLEIESLSGRKAPIYLIDFAANGTLTETLSAVSKLLGMIDIRNVDET
EFAICGKRVFAPRLLPLHLGLEEILPAYDHYMDLTKKADESPAGTAKFPRLVEPANKACR
VRLLALCLDEIFPIEAISPASKAFELGESRPCTLPYGYRNRRQKPSCTKWNERSYSHRRI
RYELPLCWLNRNKANVYFNQKRLGQSTCIFIEVILKLAVRFILPACFTKKMNAAPPSTAR
ENRPLYSALSDLKGLAFLCCAPGPDNASSLCGCSGILLEHGADSQHLTVGNVVCGIMPRP
HCEIVDIPGILLHPSPPSFSCELAASLPPQLALLLWALNQAPPLVTPPAKRVSRVLIVGA
GCGVGLVAATHFQTLGLKTFAVVCTEEQVEALVHYQFPHAAIWCYDRPDLRSALRRELGY
SSIDMVVWALKQEIDSSNNHLLNLLKHGGSFVDLVACHPESRLGWRLDVKYVHCTLDLAA
RPYHAKEFSKNLALSCEILRQKTASQRQQIMHVFFDHAHRLGQHCSLASVQMTEAATPQN
VTSPADLSKQNVSFRPGVNAVEFVSGYSHAGSVVCSLPSPIFFNKASSSNGNCESNASTA
SSSAALGTEASSNVRTGTVLIFDCGSGNTWQHLRQWLSDEGASHIVVVHACAEEGADTLG
VKTLHPSRVNGGQGCSQTLIKEVKCRPHHPEEVVELFKLLKEGLHFPLVRGIFYILGEKL
DSLLANQTTSSVHDMMKTASGAWSIHHALGQLGMEADLDFFIFFSSISALFGSISQSISA
AVHASLDALAYYRRHLGLAATSIQWAPWADGSSATSPQIVRHWLEKGGVSSVRNPLAAVS
AILKNHTAIGAVVACFHADPTIMHEMGETDQECTFLSSGPAANTRDSTSGNVKVRTNPVK
SRVFQNVSPSTDTCGENHKDELLVILTQLVRREVIEIASCYVFFEGNNLSTDESLVDLGL
DSLSAVELRHTLQQRFCVNIEPTFLQANATIDSISALLVTHVATSLTGALPVLPLSCPGL
ASAVDDCALVSLALRLPGRCDSLDAFWASLQSDSGYCRPGASEACDQCFMHRAGSGELPA
ESQSIGTNLDARKGFCWLSNRDAFDSHFFGISFTEALATDPCHRLLLEATYEALCKLNTE
QQSGTSGTPIAVFATSSSTQMRASLPSYTKPASSQNTQDNNGCLAASFLSYHLNLTGLAV
PIDGSDSASLIALDLGREHLRGTDSVCQAVVVAAGSLLPICSHGWPSACTSPTIRRFRGR
DDHAFPDRETYAVPRGEGIVSVVLQRLSVARENGNSPMAILKGISLIRMGRGERPIPSQW
RTADVKLRRKTIVEALKMSRVEPRTVAVLETDGLTGSQAEDAYTVEAMADIFGPRHLAES
CSPLVIGNASLHIGQAREASGLATLAKLVLMLERGYAPPIPRLRRLHPDVKRGILPSGFV
MFPCKKMDLLAFRQHPDHVYGPNEKRDQKEGRPLIGCVSSLGSDKTSGCFIVESSPRRHG
RTSDTRVSLERAVPLAGTKDACSHNYLHVRSTDGSESEIRGDDRAVWLFCDDLWGLQSVG
RGLYCSDPAFAALLEQAERVLGNRIPQPLSCLLYPSTTAEFQKAEDALAFPRIAAFVLFS
LQWALATCLRHQEGEPTAVMGLGVGEIAAAAVAGILSLEDAVELLELLSSETRTCDYRNK
PMPGGNVNSGGLFDRGNSGTGGCGVAQDCKSPWVLCGLNKTPTSESAALEFSVLESRRGS
SSRISSETPTSNTTPHNRDVFQERFSRKPRRATCPSPIIRHAWEKVAHGNPENDEEAELE
CPSSQSRRANCPSPAIQHACEETAHGNHANDGEADLLMDVFRFRPEPSEPLGQVTARIAL
RNATCLFISTVSGRLATDTLIRAAEYWDPLVPKTQRVHRAVETAVQVAKTAKLVCIGCSA
QDGVHLSVGLPSVHPISPSPLRIFCFTGSSPSPQLLAPCESASGSSPRVAVVEHHGADSN
LGGGAPWWKHLLFRLPQLEGFPSGCSASTRLLADRLVADVPTPDNHMINNPQTAAVQGAG
ETLGTLREGSSGEGEDGEKGYRSESVNTQHPVYKVYRRCSEPELHESELSLLCSDTVCQP
SLEKTVELFIGTGLEQQGKLSTVSSSWLVFSDIVAPSPISLYSTLAFQNEDGEQRFCTLN
VASQVATVYAEKVKTQVCSIIIECKRGFKPPREIARCHFVKNQTAVGKHEPAVSSLSRIR
WLPATKLSEGWLRTRRPHVWPCKIKVTKAACPLPTRRVDLQEIYWGKRHILCRFRMPRNP
PRDGVEKSTQLIAILARLVTVSVGVAATCVLHETETSGRYSHSHPGPQVEDDQKTHMDAL
WVCPYVPFSECWCVIRHRRNGSSIKEGKGRDWETCDVEIFSENGTAVAVVLGFGIQSHAL
SMRMMEGRGNDGDSSVSTTVCVA
>A0A2K8RHV1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MNENHAVSSRGQDQVSNEEKLVEYLKRVMADLRQTQRRLRDVEEKSREPIAIVAMSCRFP
GGVRSPEEFWELLARGEDAVSAFPEDRGWDLAELYDPDPDRSGTSYVKEGAFLSDAGAFD
PTFFGISPREALAMDPQQRLLLETSWEAMERAGITPASLRGTKAGVFVGTNGQDYTVALR
QAPKGVEGFLATSGAASVMSGRLSYTFGFEGPAVTVDTACSSSLVALHLAVQSLRQGECT
LALTGGVTVMSTPGLFVEFSRQRGLAPDGRCKAFAAAADGTGWGEGVGILLLERLSDARR
NGHPVLAVVRGSAVNQDGSSSGLTVPNGISQQRVILQALANARLSAVEVDAVEAHGTGTT
LGDPIEAQALLATYGQDRADGRPLLLGSVKSNIGHTQAAAGVAGVMKMVLAIQHGALPKT
LHVDEPSPHVDWSAGAVQLLAEKVAWPQSDEPRRAGVSAFGVSGTNAHVVLEQAPVGDED
EAADGGVGGGHSGVVPWVLSARSEAALRAQGDRLTSYVEKAPELSAEDVGWSLATARTVF
EHRAVVLAGERGGLVGGVGALAEGRDVSGLTQGVVAGADGRVVFVFPGQGWQWVGMAAGL
LESSAVFAERVGECAVALAPFVEWSLVDVLRGGEGDAAALERVDVVQPVLWAVMVSLAEV
WRSYGVEPAAVIGHSQGEIAAACVAGALSLEDAAKVVALRSKALRALSGRGGMVSVSLPV
GEVRERIARWGERLSVAAVNGPSAVVVSGDADALEELLALCEVEGIRARRVPVDYASHCA
HVEVIEGELLRELGGIGPRSSSVPFYSTVTGGVLDTAGLDAGYWYRNLRQTVRFDETVGA
LLSDGFQVFVEASAHPVLTMGVEQTADDQGTQVTAVGSLRRDEGGLDRFLTSLAEVYVGG
ASVDWSTVFQGTGARQVDLPTYAFQHQHYWIKTPSPTVGDVTSAGLGSVDHPLLGAVVGL
AGVDGVLLTGRLSLVSHGWLADHVVWGVVVVPGAALVELVLRAGDGVGCGWLEELTLEVP
LVVPERGGVQVQLSVGVPDGVGRRVVGVFSRLEGAEEESWVRNATGVLSVGGRGVVEGLG
VWPPVGGVAVDVGGVYERLAGVGLEYGPVFRGVRAAWRRGDEVFAEVALAEEQCAEAGRF
GLHPALLDAALHMAGVGPDGEETGPARLPFAWTGVSLYATGATALRVRLSPSGSEGISVL
VADVDGVPVASVDSLVGRPVAAEQLTASPQVTRDSLFTVEWDRVPTADTPAAASQARWAM
VGPDDLGLTAALGAAEQEVLSSPELATLAGNPDVVLMACVSDSDSGAEDLPTTTRHLAHR
ALCVVQEWLAEERFAGSRLVVVTRGAVAAVLDEDVLDVAAAAVWGLVRSAQAEHPDRFVL
VDVDDDTPVSAGVLRVVLECGEPQVAVRFGNVLAPRLARAVAPAEGAGLGFAWDPEGTVL
LTGATGTLGGLLARHLVAECGVRHLVLVSRRGREAAGAVELEAELVGLGASVAVVACDVA
DREALAGVLAGIPVDRPLRGVVHAAGVLDDGLIESLTPERMDTVLRPKVDAAVHLDELTR
GLDLSAFVVFSSAAATFGAAGQGNYAAANMFLDALAARRRARGLAGVSLAWGFWAERSDM
TGHLADADVARMERSGVLPLSSDEGLALLDAASAVDRPLLVPVRIAPTALRGGAGPVPPL
LRRLVRTPARRVLTDGAQGMDTPLHGDLARLAGLSESEREQALLDLVRAGVGAVLGYSGV
DEIEPERAFKELGFDSLTAVELRNRLNAATGLRLPATLVFDYPSPVALARHLRDELLGRS
EGTAAQAGRPTTVAASQDEPIAIVGMSCRYPGGVKSPEDLWRLLARGGDAIAGFPDDRGW
DLEGLYHPDPDHRGTAYAREGGFLYDAGEFDPEFFGISPREALAMDPQQRLLLETSWEAL
ERAGIDPASVRGSQTGIFAGIMHHDYGSATVPEGVEGYIGNGTAGSIASGRVSYTFGFEG
PAVTVDTACSSSLVALHLAAQSLRQGECSLALAGGVTVMSTPALFVEFSRQRGLSADGRC
KAFAGAADGTGFSEGVGMLLLERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQ
QRVIRAALASAGLSTADVDAVEAHGTGTTLGDPIEAQALLSTYGRERGAEERPLWLGSIK
SNIGHTQAAAGVAGVMKMVLAMRHGVLPKTLHVDEPSPHVDWTEGAVRLLTDAAEWPETG
HPRRAGVSSFGASGTNAHVLVEQAPEEMHVAERVAGPEMSGLVPWVVSAKSEGALRAQAE
RLLSSVRDETDAVPSVVDVASSLVTTRSVFEHRAVVLVGDHQGFTAGLEAVVDGVPAAGV
VRGSVVPGKLAVLFSGQGSQRIGMGWELYEAFPVFAEAFDEVCGRFDGLLERPLREVIGG
DVEGLDETAFTQCGLFAVEVALFRLVESWGVRPDFVAGHSIGELVAAYVAGVLSLDDACV
LVAARGRLMQQLPSGGVMVSAQAAEADVLPLLAGREAEVSLAAVNGPHSTVISGAEATVM
EIAAQFEAHGVKTKRLRVSHAFHSPLMEPMLADFRQVAEGLSYAPPRIPVVSNVTGQVAD
VEALCSAEYWVRHVRETVRFADGMAVLAEAGVTTSLELGPDGVLSGMGQECAPDIEFVAA
LRSGRDELATLQEALARIFVRGARVDWTALLAPTSIRHVELPTYAFQRKRYWLEAGGAVG
NVASAGLRSEEHPLLGAAVRLPDSDGCLFTGRLSARTHAWLADHAVLGSVVVPGTAFVDL
ALHAGSRFGCGQVDDLVLEAPLVLPERGAIQLQVMVAGADDDGRRPVTVHSRQESGDEDQ
PWTRHATGVLTQAEESESALSAELSVWPPADAEAVDISGMYERFALGGLAYGPAFQGVRA
AWRREGEVFAEVALAEEQWPDATRFRVHPALLDAALHMAGPGGLVTSDAEQVRLPFAWNG
VSVHLIGATTIRVRLTAAGGDGLSLTVADETGRLMASVAELVTRPVSAEQIDAARGAAHE
SLFQLRWNAMPLAADAPATARCALIGEEDGDLAVALRSADWQVGTHPDLEALARSGAEGE
PLPEWVLPASPIGPGGDARRGVGGAAHRALEWVQEWLAEDRFVDSRLVITTRGAVATSST
ESVDDLAGAAVWGLVRSAQAEHPGRLVLLDVDDPKELGSVPLAAALASGEPQLAVRGGRV
LSARLVRAEEQAERGASAAWDSEGTVLITGAGGTLGGLLARHLVAEHGVRHLVLLSRRGP
AAEGAAELAERLSSAGASVTWAACDVADRDALRAVLSDIPAAHPLKGVVHAAAVLDDGVI
ASLTPERLDTVLRPKAEAALALHELTAGLDLSAFVVFSSVAGMFGAAGQGNYAAANAFLD
ALVTQRRAHGLPGLSLAWGLWEERSGMTAGLAEVDRRRMDQVGISALSSAEGLALFDAAC
ASDGPVVAAARLNTTVWRSAVHEEMVEVPYVLRELVRLPARRAAAADSTGAAGAAEALRT
RLAGASYAEGERLVLDTVRRNVAAVLGHGGPETVEPGRAFKDFGFDSLTAVELRNRLGTV
TGLRLTATLVFDHPTPTVLAQHLHRELSRDVGSAATSVPVSVGLDQLEAGLSTMTWEEIG
RTDVVSRLRELLAKYGDAREVPNGNAAALVDQLESATDGELFKMVDEDLGIL
>A0A2K8QXN6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MASNEEKLLDYLKRVTADLRQTQRRLKDVESAGYEPVAIVGMSCRFPGGVRSPEELWELV
AAERDAISELPTDRNWDVENLFHPDPEHPGTSYTREGGFIDDPAGFDAAFFGISPREALG
MAPQQRLALEASWEAIEHAGVDPESLRGSRTGTFIGCDHLDYCSDASQVPEGSAGYFTIG
NSASVVSGRVAYTLGLEGAAVTVDTACSSSLVAMHLACQAIRQGECDMALAGGVAVMSST
APFIGFSELRGLAPDGRSKAFSANSDGMTLAEGVGVLLLERLADARRNGHQVLAVVRGTA
VNQDGASNGLTAPNGPSQQRVIRQALANARLSPSDVDAVEAHGTGTTLGDPIEAQALLAT
YGQERPEGHPLWLGSIKSNIGHAQMAAGAAGVIKMVMAMRHEVLPASLHIDEPTPHVDWS
AGDIHLLTEAREWPRGEHPRRAGISSFGISGTNAHVIVEQAPEEPPAAVGAGAGEPVEPV
ELAEPVEPVGGPVPWVVSARGAEALRGQARALAARVNADPGVSADEVGWSLLRSRTLFDH
RAVIIGQNREELVSGLEALAAGEPHPGVVEAGKAAEVAGQTVFLFSGQGSQRPGMGAELY
NRFPIFAEAFDEVCALLDPHLEYPLRELVFSREPEQAALLDHTTYAQAGLFALHIALARL
LDSLGVRPDTVIGHSIGEIAAAHIAGILDLPDACHLVATRATLMGGLREGGGMATIAATP
DELAEDLARYDGQVGIAALNTPGNTVISGPTDLVTNISATWAAKGRKTRTLTVSHAFHSS
LMDPILEPFKEAISGLTYHPPTIPLISNLTGQPADEAITTPDYWAQHIRQPVHFHPAVAH
IAPETGIFLELGPDPTLTTATHHTLHHHTSTEQNPTNQPTPLITPALTRKQPERQALAHA
LARLHTAGVDIDWTSWFPADPAPRVVGLPTYAFQHQRFWLAPPAARTSFEGTAGDPAEAQ
LWHAIEELDVDALSSTLRLEKDSPGIDALLPALPVLSTWRRQHRERSTIDSWRYRATWQQ
FPDPPTPTLTGTWLVVVPAGQEEHATVQVTVQALRAHGATALRHGVNAHDIDRAALHERL
ARLTEEFQPAGVISLLALDTEPLIGHSAVPAGLGATTALLQALDDAGIGTPLWCLTQGAV
ATGRGDLLPHPGQSQIWGFGRVAALEYPQRWGGLIDLPTTMTHHTAGRLAALLVPGQPED
QVAIRTTGTYARRLARVPAADTAPASWEPSGTTLITGGTGGLGAQIARWLAHRGAPRLHL
ISRSGPDAPGASELGEELTALGTDITITACDASDRAALQRLIDTVPAEHPLTAVFHTAGT
MELGQIGELDPGRLQSVLRSKALAAAHLHDLTQDLDLAAFVLFSSNAATWGSGQQAVYAA
ANTYLDALAEHRRARGLPATSLAWGPWGEAGMAADQHTLSHLKRRGLSPLPTDLAIASLH
QALTHDDTAVTIADVDWETFGRTFTAQRPSPFLTHLLPTSAEPTTPAATADDNPLRQQLG
AAPTAQRHQILVRHIQTLAATILGHPGLDAIPPGQPFQELGFDSLTAVELRNQLAASTGL
SLAPALVFDHPTPNALATYLGAELTGQRATVATRTSSVATDDEPIAIVGMACRYPGGVRS
PEELWKLVAAGRDAIGEMPTDRDWDLDTLFDPDPERLGTSYAREGGFLHDAAGFDAAFFG
ISPREALAMDPQQRLLLETAWETFESAGLDRDTLAGSNTGVFAGGTYQGYGASGSSSARE
VEGYLLAGGTPSVMSGRVAYAFGLEGPAVTVDTACSSSLVAMHLAAQALRQGECTMALAG
GVTVMATPTTFVEFSRQRGLAADGRCKPFASAADGTGWGEGAGLLLLERLSDARRNGHRV
LAVIRGSAVNQDGTSNGLTAPNGPSQQRVIGQALTNARVSPTEVDVVEGHGTGTTLGDPI
EAQALLATYGRERPEGRPLWLGSIKSNIGHTQAASGVAGVIKMVMAMRHEVLPASLHIDE
PTPHVDWSAGDVQLLAEAREWPRGEHPRRAGISSFGISGTNAHVIVEQAPEESPAAVGAG
AGEPVEPVELAESVEPVGGPVPWVVSARGAEALRGQARALAARVNADPGVSTDEVGWSLL
RSRTLFDHRAVVIGQNREELTAGLEALAAGEPHPGLVEPGEATDTAGKTVFLFSGQGSQR
PGMGAELYDRFPIFAEAFDEVCALLDPHLEHPLRQVVFDTSPEHAGLLDHTTYAQAGLFA
LHIALARLLDSVGVRPDTVIGHSIGEIAAAHIAGILDLPDACHLVATRATLMGGLREGGG
MATIAATPDELADDLAAHDGQVSIAALNTPTNTVISGPTELITDISTTWAAKGRKTRTLT
VSHAFHSPLMDPILEPFKEAISGLTYHPPTIPLISNLTGQPADEAITTPDYWAQHIRQPV
HFHPAVAHIAPETGIFLELGPDPTLTTATHHTLHHHTSTEQNPTNQPTPLITPALTRKQP
DGQALTHALARLHTAGVEIDWTSWYPATPTPRTIDLPTYAFQHQHYWLSSAPSSSPTPTE
AALVDRKFWEAVEREDLEALAATIDSPADQQPMLSAVLPTLSAWRRHHREQSVINSWRYQ
IAWKRLSAPSTPPDLSGTWLLIIPAGQSDHPGVETVAHALTTHGATLIRHVLDTHTVDRD
ALADHLTRLAMQGEPAGVLSLLALDEEPHPEYAAVPSGLAATTVLLQALGDAEIPAPLWC
LTQGAVATGPGDPLPSPRQAQTWGLGRAAALEHPRRWGGLIDLPAVIDHHTADRLAALLT
PGRPEDQTAIRAIGSYARRLRKATAPTAAPRTWQPTGTTLITGGTGGLGAHVARWLARLG
APHLHLISRSGPDAPGAAQLTQELADLGTAVTITACDASDRAALQRLLDTIPAEHPLTTV
IHAAGTSDTELLADLGPERLELVLGPKALAAAHLHELTQELDLSAFVLFSSGAAAWGGSR
QGAYAAANTYLDALAEHRRARGLPATSLAWGPWGDAGMAADETALAFYGRRGLSPLSPEL
AVASLQHALDHRDTTITVADIDWEKFPTAFTAQRPSPLLDDLITAIESPAEPITGASTGT
SLQQRLSAGTPEQQHQLLLERVQSLAASILGHSGPDAIPPAQPFQELGFDSLTAVELRNQ
LATATGIDLAPALVFDHPSPNALATYLRAELTGQQTAVAAHSPTTAAQDEPIAIVGMACR
YPGDAHSPQDLWELVIAHRDAIAQMPTDRNWDLDALYDPDPDRAGTSYVREGGFLRHAAE
FDPAFFGISPREAIAMDPQQRLLLETAWETFESAGLDRDTLAGSNTGVFAGVTSQDYLSL
TGDTASDVEGYVATGNIGSVVSGRVAYSFGLEGPAVTVDTACSSSLVAMHLAAQALRQGE
CTMALAGGVTVMATPGAFIEFSRQRGLAPDARCKPFAAAADGMVWGEGVGLVLLERLSDA
RRNGHRVLAVVRGSAVNQDGTSNGLTAPNGPSQQRVIRQALANARLSPSDVDAVEAHGTG
TTLGDPIEAQALLATYGQERPEGHPLWLGSIKSNIGHTQAAAGVAGVIKMVMAMRHGVLP
ASLHIDEPSPNVDWNAGDLRLLAETVPWPQGDRPRRAGVSSFGISGTNAHLILEQAPEPA
GPAPVSDVAGVVPWVVSAQSDAALRGQARALAGHIIGDPEVSAGEVGWSLLRSRTLFDHR
AVVIGQNREELTAGLEALAAGEPHPGLVEPGEATDTTGKTVFLFSGQGSQRPGMGAELYD
RFPIFAEAFDEVCALLDPHLEHPLRQVVFDTDPEHAGLLDHTTYAQAGLFALHIALARLL
DSLGVRPDTVIGHSIGEIAAAHIAGILDLPDACHLVATRATLMGQLTQGGSMATIAATPD
ELAEDLARYDGQVGIAALNTPGNTVISGPTDLVTNISATWAAKGRKTRTLTVSHAFHSSL
MDPILEPFKEATSGLTYHPPTIPLISNLTGQPADEHITTPDYWAQHIRQPVHFHPAVAHI
APETGIFLELGPDPTLTTATHHTLHHHTSTEQNPTNQPTPLIASTLTHKRPDTHALTHTL
AQLHTSGTTIDWTSWYPATPTPRTIDLPTYAFQHQHYWLAPPAPRADSRLNGHNPAEARL
WDAIEELDVDALASTLDLEKDSPGVDALLPALPVLSTWRRRHRERSTIDSWRYRVAWKQV
RDPATAPTLSGTWLLLVPTGLEEHPAVHATVEALDAHGAAHEVLSIDGADARRDAIAPLL
SQLPDGSTPEGILSLLALDRTPHPDHPAVPTGLAATAALVQALGEAPLIAPLWCVTQGAV
ATNAADPLPHPHQAQIWGMGRVAALEHPRLWGGLIDLPAVADARTPARIAAMLVPGQPED
QVAIRSTVLARRLERAVCPDTAPTAWRPAGTTLITGGTGGLGAHVARWLARQGAPHLHLV
SRSGPDAPGAAQLAQELNDLGSAITITACDVSDRAALQRLLDTIPAEHPLTTVIHAAGLP
ENTPLAELDLPGIDAVLRPKALAAALLHELTEELDLSAFVLFSSGAAAWGGGRQPSYAAA
NAYLDALAEHRRARGLAATSLAWAPWSDAGMASDEAAVDYYRRRGMRPLDTDLAIASLQH
ALDHGDTTITIADIDWERFPAGFTAQRPSPLLSDLAAAASPGPDAAPDATAAMSGSLQRQ
LATGTHAQRHQLLLHHIQTHAAAILGHPTIDAIPPTQPFQELGFDSLTAVEFGHRLSAAT
GVDLPPTLVFDHPTPKELADYLRERLVEGEPTSEGHLLSELDRWDSVSEPSAVDEAARRR
ITGRLRLLLAKWNDTERGAERSAAHSELETATAEDIFDLISDEFGKSDEFRKS
>A0A2K8RA73|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MVSESVDFTPEHTEMGDASPRGASPWRDRLAALPEAERAEALTAWVGEIVEQALKDKAPD
VLDPERPFLDLGFDSLATVDLHARLTAATGLRLPVTLAFDHPTPADLARHVRTELLGGND
DSDVSPADAGMGPIAADEPIAIVGMSCRFPGAVGSPEELWEIVAGGKDVISEFPGTRGWD
LAGLYDPDPDRPGSSYTREGGFLHDADEFDPAFFGISPREALAMDPQQRLLMETSWEVFE
RAGIDPAILRGGRTGVFVGAETQDYGPRLHEAEQGFEGYLVTGNAASVASGRIAYTFGFE
GPTVTVDTACSSSLVALHLAVQALRSGECTMALAGGAAVMANPGSFIAFSRQRGLAADGR
CKPFAAAADGTAWGEGVGMLLVERLSDAQRNGHRILAVVRGTAINQDGASNGLTAPSGPA
QQRVIRQALANAGLTAGEVDAVEAHGTGTTLGDPIEAQALLATYGQNREADRPLWLGSLK
SNIGHTQSAAGVGGIIKMVMAMRHGVLPRSLHIDEPTPHVDWTGGDVELLTEARPWPESD
RPRRAGVSSFGMSGTNAHAIIEQPPAPAEERADAEDPDDEAAAAPALLPWTLSAKTTDAL
RGQAERLYALLEADPGLALTDIGHSLATTRATFEQRAVLLAGDRDGFRSALRTLADGGDA
PSVVRGAPAAGKLALLFTGQGSQRLGMGRELYGAYPVFAEALDDACWYLKEQLERPLLDV
LFAEEGTPEADLLDRTDYTQPALFAVEVALYRLLESWGLRPELLAGHSIGELAAAHVAGV
LSLEDAAALVAARGRLMQELPAGGAMVAVQASEDEVLPLLAGREDRIGIAAVNGPQSVVV
SGAEEDALEIAAAFEERGRKTKRLTVSHAFHSPLMDGMLAEFRRVAQVLDYAPPRIPVVS
TVTGRVATAEELCSPEYWVRHVREAVRFLDGVRTLADKGATTFLELGPDAVLTAMAQDCL
PDAEGTAYAPALRGGRPEDETLTAALALAYVRGKKADWAAPYAATDARPIDLPTYAFQRQ
RYWLNAPAPAGSAAEAAPGSAVDGRFWDVVERGDVAALAAELAVDPGVSLGEVLPALSLW
RRQESVRSAVDGWRYRVLWRPVTDRLSAAGVLGGSWVVVVPSGGAGGVWAGGVVRLLAGR
GVDVRVVESDAVDRAGLADELRTAVVGGSVAGVFSLLAVGGESGLLRTAALTQALGDVGV
GARLWVATRGAVSVGRSDGVVDPGQASVWGLGRVAALELPERWGGLVDLPESVDERVLGR
LAGVLAGAGGEDQVAVRPSGVFGRRLVRAATPGSATGAASDGSWTPGAGSVLVTGGTGAL
GAQLARWLVECGAEHLVLTSRRGLEAPGAVELRDELAASGARVTVAACDVADRDALAELL
AGLPAELPLTAVVHAAGVLDDGVLDSLTPERFASVLRAKADAARHLDELTRDLDLSAFVL
FSSITGSVGAAGQGNYAAANAYLDALAELRRAEGLPATSIAWGPWAEGGMAGDDAMERRM
RREGMPPMAPESALAALRQALELDDTAVTVADIDWEHYTGTLTAVRPSPLIAELAAEAGQ
RAATGADTAKVVTDADAASPLGERLSGLPKAEQDRALLELVRAQVASVLGHGGADAVEAG
RAFKELGFDSLAAIELRNRLNAATGLRLAATLIYDYPNATALADHLRTELLGADVAVDGG
VVAPSAVAVADDPIAIVAMSCRFPGGVRSPEELWELLTAGGDAVAEFPSDRGWDLAGLYD
PDPDRQGTTYTREGGFLYDAGDFDASFFGISPREALAMDPQQRLLLETSWEAFERAGIDP
ATLRGSRTGVFAGTNGQDYAGLVATPPEGLEGHLGTGNAASVVSGRLSYTFGLEGPAVTV
DTACSSSLVALHMAVQSLRSGECTMALAGGVTVMSTPDAFVDFSRQRGLAEDGRIKAFAA
GADGTGWGEGVGMLLVERLSDAEKNGHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIR
QALAGAGLSAGDVDAVEAHGTGTTLGDPIEAQALLATYGRERDADQPLWLGSIKSNIGHT
QAAAGVAGIIKMVLAMRHGVLPRTLHVDAPSPHVDWSTGAVSLLTEQVEWPETGRPRRAG
VSSFGLSGTNAHTIIEQAPALPAASAKEPEPREPAVLPWLLSAKDGQALHAQAAQLATHL
RTHPELSATDIAFSLATSRAALERRAALVTTDRETFLAGLDALARGESVPDVVEGTAAEG
KVAFLFTGQGSQRLGMGRELYDAYLVFADALDEVCAHLDLYLERPLRDVLFGEDAAVLDQ
TAFTQPALFAVEVALFRLVEAWGLKADFLSGHSIGELAAAHVAGVLSLADAAKLVAARGR
LMQELPAGGAMVAVQASEDEVLPLLTERVSIAALNGPTSVVIAGDEDVALEIAASFEAQG
RKTKRLTVSHAFHSPRMDGMLDAFREVAEGLTYEAPRIPIVSNLTGGVVSAEEITSPEFW
VRHVREAVRFLDGVRTLEAQGVTTFVELGPDGVLSAMAQECVTGDDVAFAAALRKGRAEA
ESVTAALAVPHVRGQSPDWREYFEGTGARRVELPTYAFQRTRYWWEEAPAAEAALGGAVD
GRFWDVVERGDVAALAAELAVDPGVSLGEVLPALSLWRRQESVRSAVDGWRYRVLWRPVT
DRLSAAGVLGGSWVVVVPAGEAGGVWAGGVVRLLAGRGVDVRVVESDAVDRAGLADELRT
AVAGGSVAGVFSLLAVGGESGLLRTAALAQALGDVGVGAPLWVATRGAVSVGRSDGVVDP
GQASVWGLGRVAALELPERWGGLVDLPETADERALGRLAGVLAGASGEDQVAVRASGVFG
RRLTEASGARTSGDEDWRASGSVLVTGGTGALGAQLARWLVECGAEHLVLTSRRGLDAPG
AVELRDELAASGARVTVAACDVADRDALAELLAGLPAEFPLTAVVHAAGVLDDGLVDTLD
AERLERVVRAKATSARNLHELTRDLDLTAFVLFSSFAGSVGAAGQGNYAAANAYLDALAE
LRRAEGLPATSIAWGPWAEGGMAADEALERRMRRDGVPPMAPESALAALRQALELDDTAV
TVADIDWDRFLAEFTAARPSALFGEVRAARPAPAVEGVPRPAATGGTGTLAERLSGLTEN
ERAQTLLELVRAQVASVLGHGGADAVGAGRAFKELGFDSLTAVELRNRLNAATGLRLPAT
LIYDYPNATALADHLRTELLGADVAVTGGVAAPTVAVADDPIAIVAMSCRFPGGVRSPEE
LWELLTAGGDAVAEFPSDRGWDLAGLYDPDPDRQGTTYTREGGFLYDVADFDASFFGISP
REALAMDPQQRLLLETSWEAFERAGIDPDALRGQQVGVFAGTNGQDYLSLLMQAPEGLEG
HLGTGNAASVVSGRLSYTFGLEGPAVTVDTACSSSLVALHLAVQALRQGECTMALAGGVT
VMSTPENFIDFSRQRGLAADGRIKAFAAGADGTGWGEGVGMLLVERLSDARRNGHPVLAL
VRGSAINQDGASNGLTAPNGPSQQRVIRQALTSAGLTTGDVDVVEAHGTGTTLGDPIEAQ
ALLATYGRERDADQPLWLGSIKSNIGHTQAAAGVAGIIKMVLAMRHGVLPRTLHVDAPSP
HVDWSTGAVSLLTEQVEWPETGRPRRAGISSFGISGTNAHTIVEQAPAVDTPAEAPEPNG
LGGLLPFVLSAKNAEALREQAARLRTHIAARPESAPLDIAHALATGRAALERRAVLTVGD
RDELLRSLDALARGESVPSVVEGTVAEGKVAFLFTGQGSQRLGMGRELYDAYPVFADALD
EVCAHLDLYLERPLRDVLFGEDTEALDRTGFTQPALFAVEVALFRLVEAWGLKADFLSGH
SIGELAAAHVAGVLSLADAAQLVAARGRLMQELPAGGAMIAVQASEDEVSPLLTERVSIA
ALNGPNSVVIAGDEDDAVAIAAGLEAQGRKTKRLTVSHAFHSPRMDGMLEAFREVAEGLT
YEAPRIPIVSNLTGAVVSAEEIATADFWVRHVREAVRFLDGVRTLEAQGVTTYLELGPDG
VLSAMAQECVTGEDTAFAAVLRKDRPEAEALMTALARAHVRGVTPDWAAVFAGTGAAPVD
PADLPTYAFQRQRYWPSAAALAAGDPESIGLGDIDHPLLGAAVALADADGLLLTGVLSLR
THPWLADHAVMDTVLLPGTAFVELAGAAGAQVGCERLDELTLEAPLVLPEHTGVRVQLVV
DGPDESGRRSFSLHSRRQDALGTEPWTRHATGVLAPGTRISGEPDELAVWPPRGATPIPV
EGRYEELAGAGLGYGPVFQGLKGAWRLGENLYAEVGFPEDAPLPSGAEAERFGLHPALLD
AALHVIGLDSADRETALAEGALLPFAWNGVQLHAAGAGALRVRLSERSANAVSLLVADGT
GRAVATVESVALRAASADQVRAARGGLHESLFRLDWTAVPAPATGAATGDWAVLGADGAQ
LAMLEGAFGTGIRLAAYRDLAVLRTAVEAGAPAPDTVLLAGIGGGGDASAVHEATQAVLS
LLQEWLADERFTASRLVLLTRGAVATEPGADVADLPYAAVRGLFRSAQSENPGRLVLLDV
DGQEDSYRTVPAALGVDEAELALRAGVALAPRLARVPLTESTGGTENTRGTENTGGTEAI
DGAGNTDGTESIDSAENTHRTENTDAVGTRAESGAPSYDPNGTVLITGATGNLGGLFARH
LVSAHGVRRLLLVSRRGAEADGAEELGAELTAAGAMVTWAACDVADRDALAATLAAIPAE
HPLTAVVHTAGVLDDGILGSLTPERVTHVMRPKVDAALNLHELTRDQELSAFVLFSGAAA
VFGAPGQASYAAANSFLEALAQHRVAQGLPATALAWGLWAGAGMGSGLDEVDLRRIARGG
VAPIAADEGLALFDAARADGAPVLFPMRLDHAGLRTEATATGTVPALFRGLVRTPVRRAA
AVAATADGSSLAQRLAGLARSEQDRELLELVCGRVAAVLGYAGPEAVEAGRAFKELGFDS
LTAVELRNDLKTVTGLRLPATLVFDYPTPSALAGHLREELLGAEEEIAAPLVPVRAGATP
AVDDDPIVIVGMSCRYPGGVRTPEELWELVATGGDGISGFPVDRGWDLDGLYHPDPDHTG
TSYTREGGFLHDAADFDPDFFGISPREALAMDPQQRLLLETSWEAFERAGIDPSTVRGSR
TGVFAGVMYHDYVTGLDGIPDGVEGYIGTGNAGSIASGRVAYTFGLEGPAVTVDTACSSS
LVALHWAIQALRAGECTMALAGGVAVMATPETFIDFSRQRGLATDGRCKSFAASADGTGW
GEGAGMLLVERLSDARKNGHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRQALAAAG
LSAGEVDVVEAHGTGTTLGDPIEAQALLATYGRERDADQPLWLGSIKSNIGHTQAAAGVA
GIIKMVLAMRHGVLPQTLHVDEPSPNVEWEDGAVSLLTERMEWPDTGRPRRAAVSSFGIS
GTNAHTIIEQPPAAEDHDGAVARPSAVPPVLPWPLSAVGQDALRDQARRLRDRLRSADED
TDLAAIGYTLAAGRAAFEDRAVLVADGREGFLRTLEALASGEPANGLVQGSPVAGKLAFL
FTGQGSQRLGMGRELYDAYPVFAEALDAVCDELDVNLERPLKTVVFADDAAALDRTGFTQ
PALFAVEVALFRLVEAWGLRPDFLSGHSIGELAAAHVAGVLSLADACRLVAARGRLMQEL
PAGGAMVAVQASEDEVAPLLTERVSIAALNGPTSVVIAGDEDAALEIAASFEARGRKTKR
LTVSHAFHSPRMDGMLDAFREVAQGLSYEAPRIPIVSNLTGAVVSAEEIATADFWVRHVR
EAVRFLDGVRTLEAQGVTTYLELGPDGVLSALAQECVTGGDAAFAAALRKDRPEAETVTT
ALAALHVRGVALDWEAFYGGTAVRRVELPTYAFQRRRYWLDVRSAATATPGATAQDAVDA
RFWEAVEREDLASLAETLNLGTESNGALEALLPSLSSWRRQQSERSTLDGWRYRVSWKPV
TDRATASPSGGWLVVVPAEAAEDAWVEGAVRMLNDRGADVHRVELPAGDDRAALAERLAA
AIGDEAVTGGVLSLLALADGDGEGLPRTAALTQALGDMGVGAPLWVATRGAVAVGRSDGM
VSPAQARLWGLGRVAALEVPERWGGLVDLPAAADERALGRLAEVLAGAGGEDQVAVRASG
VFGRRLVRASAPGSDGGSWTPGAGTTLVTGGTGALGAQVARWLVANGAGHLLLTSRRGLD
APGAVELRDELAASGARVTVAACDVADRDALARLLDAIPAELPLTGVVHTAGVLDDGVLD
SLTPERFTAVLRAKAVAAAHLDELTRDRELSAFVLFSSTSGTFGAPGQGNYAAANAYVDA
LAERRRAEGLPATSIAWGPWAEGGMATDGALEQRLRRGGLPPMDAELAIGALQRALDLDD
TVVTVADIDWDRFAPDFTAARPSRLLADLPEIRAAAEDTAAEPAADGSSLAARLAGLGEA
ERDRLLLDLVRTQVAAVLGHDGSESIGADRAFGELGFDSLTAVELRNRLGAASGVQLPAT
LVFDYPTASALAGYLRGELIGTDTGASADTAAESTRSTAVTAAVDDDPIAIVAMSCRFPG
GVRSPEELWQLLTAGGDAIAEFPADRGWDLDALYDPDPDHRGTFYAREGGFLYDAGHFDA
GFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATLRGTSAGVFVGSNGQDYDASLHT
VPEGVEGYLGTGNAASVVSGRLAYTFGLEGPAVTVDTACSSSLVALHWAIQALRQGECSL
ALAGGVTVMSSPGAYIEFSRQRGLAADGRCKAFAAGADGTGWGEGVGMLLVERLSDAREN
GHPVLAIVRGSAINQDGASNGLTAPNGPAQQRVIRQALAGAGLTTGDVDAVEAHGTGTRL
GDPIEAQALLATYGRDRDAERPLWLGAIKSNIGHTQAASGVAGVIKMVLAMRHGVLPRTL
HVDEPSPHVDWSTGAVSLLTEQVEWPETGRPRRAGVSSFGFSGTNAHTVLEQAPVDDEPA
ESTPRRPLMRPDVVAWPLSAKGEDALRAQAERLRAHVEAEAGLDAVDVAYSLATTRSALE
HRAVVLGPDRDRLLAGLTALARGESAAQLIRGVPAEGRTAVLFTGQGSQRLGMGRELYET
SPVFAEALDAVCAELDRHLERPLYDVLFGDDKAPLDRTGFTQPALFAVEVALFRLAEAAG
LRPDLLAGHSIGELAAAHVAGVLSLEDAAALVAARGRLMQELPAGGAMIAVQAAEDEVEP
LLTDRVGIAALNGPTSVVIAGDEDAALEVAASFEARGRKTKRLAVSHAFHSPLMDGMLAE
FRKVAEGLRYGAPRIPIVSTVTGQPVTDELGMAADYWVRHVRHAVRFLDGVRTLEAQGVT
TYVELGPDGVLSAMAQDCVTAGAEGAEEVAFVPVLRAGRPEPETLTGALATLHVRGAALD
WAALFAGTGAHRVDLPTYAFQRRRYWLEGTPRHTSGEEATAVDTAGARFWEAVESDDLAS
LSDAVGIDVDQPLSALLPALSAWRRREREQSALDGRRYRVTWKPLEEPRLAAAPGVWLVA
EPAVAAGHAEAVRRVVDALADRGADIRRLTPADGPADGADLDRDALADRIRWAAAEEPVH
GVLSLLALDERAHPDHPAVPTGLLRTGVLVQALGDAELDAPLWCATTGAVSTAASEPVGS
AAQAQIWGLGRVVALEHPERWGGLLDLPATLDERAADRLAGVLGGHGDGHEDQLAIRTAG
ILARRIAHAESTPATGAPWRPRGTVLVTGGTGALGAHVARWLVENGAEQVVLTSRRGPDA
PGADQLTAELTEKGAQVTVVACDVTDRDAVAGLLTRIRDAHPHHPLTAVVHTAGAGQFAP
LAETTPADVADVVAAKVAGAAHLDALLGDTELDAFVLFSSIAGVWGSGGQGAYAAGNAFL
DALAEQRRARGLTATSVAWGPWADGGLVADDEAAEQLRRRGLPVMAPHSAIAALQQALDR
NETAVAVADVDWGRFAPAFTAARPRPLIADLPEVRAALAPDPAEGADGGTAEAPAESLRQ
RLAGLTGPEAERALLDLVRTEVAAVLGHDDTTAVQAGRAFKELGFDSLTAVELRNRLNAA
TGLQFTATLVFDHPTPGVLADVLRADLLGEDTTPELPALAEIDKLEFALSHVSDDATERE
RVTARLEALLRTWNETGNAAGADGADDDELDLDAASAEDIFDIINNEFGRS
>A0A2K8RH69|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MLRTELIRPIQDLLTEQSRRFGTKTAYSDARRAISYAELETRTRRLAGHLAGLSLLPGDR
VAMFLGNRVEMVESYFAVVRASGIGVPVNPHVSQAELEHLLTVSGSQVVITDTAHLPLLR
RLNPGPCPLTVLVVGEDPVPAGCLSYERFATTEPGTPARDDHGLDDIAWMLFTSGTTSNP
KGVLATQRNCLWSVAASYVPALGLTAEDRVLWPLPLFHSLSHIVCVLAVTAVGATARITD
GHSAEDVLEQWGQERSTVIAGVPTLYHYLVRASKAPGFTAPELRVGLVGGAVTTAALRHS
VEDAFGAPLIDAYGSTETSGSIAINWPTGARVEGSCGLPVPGLALRVVDHRTGLDVPDGT
EGEVWVRGPNIMAGYHNQPEATAEALRDGWFHTGDLARRDRDGYLTITGRLKELIIRAGE
NIHPVEVEDVLRMAPGVADAAVVGKPHDVFGEVPVAFIVPAPGGFDPAQALALCRERLSY
FKVPEELYEITRIPRTATGKVTRHRLLDGPARLRAVGNAYHDALFRTKWIPQPSAPRPSA
SPLSVARPRPGRWVLLGRRPPELAGLSRATGTEPAERLDTADDVAGLRAAVATGGAPPVV
ALLPTPADTTEGVLREVETWLASAELSDALLVVLTRSAMATTTGEDVRNPEQAALWGLVR
SLQAAHPGRLAIVDLDEPEDELNGERDGEPDDEACVDALVAAVASGEPQSAVRSGVVLLP
RLERVALDRGLDGGPEAGADGGGDTERASSVAFDPDGTAVVTGVDTRRGAVIARHLATGY
GIRRLLLIAPPGQGGLAGELCAQLTGAGADVQLVECDLDNRTKLRRALAKAKSPLNVVVH
AWEAVDEPSDGRVAAEARTLHELTRNADLTAFVLSSSTKGLLGAAGETTEAASAAFLDAY
AQHLRMRGTPARSIAWGPWQGETDETAGALSRQQALAALDAALTVDQAQLAAMKLDSTAV
PTGTTSPLLKDLLDIPARAATVDDAVTVALRERLMEAHEAERDRLLTELVREHLADLLGL
ADKQAVEPDRAFTDLGLTSVTVVELRNRLSEATGLRLPATSAFDHPTPVALGSMLRRELL
GGSTAVASGLSTSLASAPVSVPASAPAVVAVDDPIAIVGMACRLPGGVGSPEELWELVLA
GGEGIGEFPADRGWDLEKLFDPDPDHAGTSYARRGGFLHDAREFDADFFGISPREALAMD
PQQRLLLETSWEALERAGIDPVSLRGQDVGVFAGMMHQNYGVGAGEGTDAPVGLEGHLMT
GTSASVVSGRVSYVLGFEGPAVTVDTACSSSLVALHLAAQALRAGECSMALAGGVTVMAG
PDSFVEFSRQRGLAVDGRCKSFSASADGTGWAEGVGVVVLERLSVAERCGHRVLAVVRGS
AVNQDGASNGLTAPNGPSQQRVIRRALAGAGLVAADVDAVEAHGTGTPLGDPIEAQAVLA
TYGQDRDRPLLMGSLKSNIGHAQAAAGVAGVIKMVLALRYGVLPRTLHVDEPSPQVDWSS
GAVELLTEQRVWPEVGRPRRAGVSAFGVSGTNAHVILEQAPDRPKSGVPAAEAPGGVVPL
VVSGRGGAGLRGQARSLLDFLEHHPDVGVVELGAALASGRAALSDRAVVVAGDQGEALTG
LAVVAEGGGSGSADVRGRVAFVFPGQGAQWVGMGAELLESSPVFAEGLRECAEALDPLTG
WSLLDVVRGVGGAPGLDRVDVVQPVSFAVMVGLARVWLAAGVVPSVVVGHSQGEIAAACV
AGGLSLEDAARVVVLRGRAVAAGLSGRGGMVSLALGVAEAEGLVERWGGRVEVAAVNGPS
SVVVAGEPDALRELVAECEDAGVRARWVDVDYASHTAQVEAVEGELARSLAQIRPVSSRI
PFFSTVEAGWLDTAELDAGYWYRNLRSTVRFGPSIERLLEADFRAFVEVSAHPVLTMGIE
AAAERADIGPVVVTGTLRRDEGDMRRVLTSLAEAYVHGVPVNWTALFDDIPAHAAPDLPT
YAFQRQHYWLKSGRRTGEVTAVGLAGAQHPLLGAWVELPDMDGALFTSRLSLSTHPWLAD
HTVAGAVVLPGSAFVELAVRAGDEVGCGVVDELLIEAPLVFMEGMSVQLQVVVDGADDSG
RRRLTVHSRRQGHGSDGADWTRHATGTLAQAATTTAPEIDLAPWPPTGATPVDVDQVYEE
LVRGGRGIGPAFRVLRSAWTRGADVFAEVELADDQQPDTTRYALHPVLLEAVCHADTHRG
ASALPATYRAVSLSATGASALRVRISPDGQGGVTLELADSAGGAVGSVGSVTSRPLPAEG
LASGAGTAPHDALFQVEWFPLPVVSAAPALATLDPVRVTSPAELTTFAAQGNVPPFVRAE
LTDTTLGLRALTAQALEWVQAWLAAPDSGSRLVIVTREITDPVCAAVWGLVRSAQSEAPD
RLVLVAMDEDDASRALLPAALVTGEPQIAINAGVASVPRLVRAVPDEEAPHRPLDPAGTV
LITGGTGALGRLLARHLAAEHGVRNLLLVSRRGPAAEGVAELESELAALGASVRTVARDI
GDRTAVADLLDSIPADAPLTAVVHTAGVLDDGMVTAMTPGRLDTILHPKADAAVILHELT
CDMDLAAFVMFSSAAGVFGNPGQANYAAANAFLDALAERRGAAGLPATALAWGHWALSSE
MTAHLTTSDLRQHTRRFGMTSLSEETGLALFDAGLRSATPALVAARLDLAGLRADAAATP
VVPLLHKLVPPGRRVVSPTVSPRTDLVRRLESSDPAERERTLLDLVTHHAAQVLGHSSAE
GIAARRAFRELGFDSLTSVELRNRLNAATALRLPSTLLYDHPSPLALTRHLHAELLGAPS
ALAAPQPAGGASDDGIAIVAMSCRFPGGVSSPEDFWRLISEGGDAVGDFPDDRGWDLSAL
YDRDPDHPGTFYVRHGAFLPDAAGFDADFFGISPREALAMDPQQRLLLETSWEVFERAGI
DPTTLGGSAVGVFTGMNTQDYAIRLRHVPDEVEGHRITGVSAAVLSGRVAYTLGLEGPAV
TVDTACSSSLVALHLAAQALRAGECSMALAGGVTVMAGPDAFVDFSRQRGLSVDGRCKPF
AASADGTGWAEGVGVLLLERLSDAERNGHQVLAVVRGSAVNQDGASNGLTAPNGPSQQRV
IRQALASAGVAAADVDVVEAHGTGTALGDPIEAQAIIATYGQDRDRPLWLGSVKSNIGHA
QAAAGVAGVIKTVMAMRHGVLPRTLHVDAPTPEVDWSAGSVSLLTEERPWPEAERPRRAG
VSAFGVSGTNAHVIVEQAPATVAAPAPEDPDTIPAVPWVISARSADALHGQAARLAEFAR
THPELDPGDIAHSLITTRAALEHRAVVVGTGRAELLSGLEAITGPTDGPVARGVPSPGRL
AVLFTGQGSQHAGMGRELHARYPVFRDAFDAACARLDRHLVDAGHTTRPVRDVVFAQPGS
PEAELLDRTVFAQAGLFALETALFRLYESWGVRPDILAGHSVGELTAAHVAGVLSLDDAA
ALLAARARLMQALPGGAMVALNAPEAMVRSLLADAPGAVDIAAVNGPASVVVSGDEDAVV
AVERQCAAKGYRTKRLRVSHAFHSAHMDGMLDAFRAIAAGLTYAPPAVPIVSNVTGELAT
IDQLCSPDYWVEHARRTVRFLDGVRTLHTWDVMTFLELGPGGVLTAMAQEALGDGADPAM
FVPTLHGEQADPLAAVAALARLHVRGVPVDWTALLPGTSRPRVDLPTYAFQHRRYWPDAP
ASDALLSDAAAPGALVTDSGSAGELRPADRSLPEAAALQGGGAAPFVERLMAGTEAERHR
LVLDLVLTSSAAVLGHDDASAIDGERAFQDLGFDSLNVVRLRNRLRELTGAELPTTLAFD
HPTPAALASFLHARLLGQHTGRTGSAWPAGDPTEPIAIVGMACRLPGGVASPEELWDLLL
AGGEGIGEFPADRGWDLEKLFDPDPDHAGTSYTRRGGFLYDAGEFDADFFGISPREALAM
DPQQRLLLETSWEALERAGIDPVSLRGQDIGVFAGMVNHDYTSRLDTAPDGSEGYLMTGG
AGSVLSGRVSYVLGFEGPAVTVDTACSSSLVALHLAAQALRAGECSMALAGGVTVMAGPD
AFVEFSRQRGLAPDGRSKSFAAAADGTGWAEGVGVVLVERLSDAERNGHRVLAVVRGSAV
NQDGASNGLTAPNGPSQQRVIRRALAGAGLVAADVDVVEAHGTGTPLGDPIEAQAVLATY
GQDRPEGRPLLMGSLKSNIGHAQAAAGVAGVIKMVLALRYGVLPRTLHVDEPSPQVDWSS
GAVELLTEQRVWPEVGRPRRAGVSAFGVSGTNAHVILEQPSEVPNSELPAPQLPGGLALL
PVSARGEDALRAQAQRLLSFLDQRPDQDLGELSLALGCGRAGLSDRGVVVAGGREELLVG
LGGLVRGEGGVGVVSGSVVRGRLGVLFAGQGCQRVGMGRGLYEVFPVFRDAFDVVCEVLD
RELGVVGVVGSVREVVFGDGGLLERTVFAQAGLFAVEVGLFRLVESWGVVVDVVGGHSVG
EVTAAYVAGVLSLEDAAVLVAARGRLMEALPEGGAMVAVGAGEDVVRPLLVAGVDIAAVN
GPAAVVLSGDEGPVLRVARDVSEQGCRTRRLAVSHAFHSARMEPMLEEFREAIADLSFAA
PVIPLVSNVTGRLADAEVVCSPEYWVEHVRSAVRFADGVRALADYGVGTYLELAPDAVLS
AMVGDCLPGGSAAESVVVPSLRREGDEPRALMTAIAQLHVAGVPIDFGALFGGAVPPAHL
PDLPTYAFQRAHYWLHDTRPASPQGPATASDDTDARFWAAVEREDLGSVAEALELANGED
DRAALDAVGGALGVLSDWRRKRGEKSAADRLRYQATWKPLPGAASGVPNGTWLVVLPYGC
QDDDYAARVVPALNRQGLRTTTLRLDGAETADRTALAETLRSALADHEDIGGVLSLLALD
QRIRTGSATLTEGVAATLTLVQALGDLGSSGSSGSASSLSSGHRLYCATRGAVSVGAADG
LIAPEQGAVWGLGLAVALEQPDRWGALVDLPEVFDDRAARALLGALADPGDEDQLAIRTT
GAFVRRLRSHPLPTDVAKPEWRPRGTVLVTGGTEGLGRHAARWLAGAGAEHLVLTVQSDP
EAPRVVALRDELSDQGAKVTVCPADLTDRDAVERLLTGPAAYPELSGVVHTADLARVAQA
DATGAAELAETLAAKVDGLLHLDALLADRDLDLFVVFSSVASVWGGGGQGLIGAANAQLD
ALVERRRARGLVATSVAWGVIDGFGVAADATAQEQLRRRGVLPMAPEAAMAALTHAVRHD
DTLVAVADIDWSAFVPAFTSLRPSPLIADLPGVQEIVDSLRPDDATDESASEFLRDLAGA
SDAERERALMKVVRENTALALGHSGVEAVKPQRAFQEMGFDSLAAVNLRNTLGAALSTQL
PATLVFDYPTPTALVEYLRTELLGDQGEDEITEADEEEIRRVLAAVPLSRFREAGVLDAL
RSLARTDAAAPDGRGSSADEELDLIDGMDIAGLVQRAFDGTQL
>A0A2K8RG82|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MHVVDSVFVMPGTVAAPRGGILCDLHNRYETVRETLSRIDKAAREMGLPNISTRLVEQNE
TSDRRGPEVQYLEIFAVSIATHHMLIAEGVKPVAIVGQSIGELWALAAAGHLSVEDAARL
AVARSQVLTQQGWGGKMLAVGVDGRRAESLAELINHPHLVLACENAPRQSVISGPEALIE
HVERVADALGWPSLQLDVPHPTHTPAMAQAARALRETAPRVPYGAGRWRVRSPWMGRDVG
DDDPVDLVAGALTARVRMLHTIRELHAAGADAFVECGEWPVVTKFVEASIPGVQCVVPLS
ESDPVEAVRALVADSTDVGTFRSRLAAPSRNGDGPVVRVSEPAPAGAVATLPVADLLTRT
AVPAPAAPVSYVAPVSAPAHAAPAPPAAPVTVAPVAVAPAPPAVVAAPAAVAPTVAPAAV
APVASPSPAGLDYDTVLTELRTLYGDFLGYPPDLLGEDDGLEADLGVESLKQVALLGRVS
DRFDLPDLRSDSSLLTAGTLRRIAETVVRARAEAAGR
>A0A445NI48|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces netropsis|TrEMBL
MPSGDVHHHEDHKEEAIAIVGAACRLPGGIDTLDGLWAVLRAGRDVIGDVPPERFDIADF
VDPGRRRAGKSYTAAGGFLEDVSGFDADFFGISPREATRVDPQQRLLLEMAVEALDDAGM
CRDTWAGADVGVFVGASSRDYADLQSARPATMNAYSMTGVAASVLANRLSHAFDWHGESV
AVDTACSSSLFAVHRACDYLRASRGPVALAGGVNVLLNPFGYVGFSAASMLSPTGRCQTF
SAAADGFVRSEGGGVILLKRLGDALADGDRIHGTIVTTGANCDGRTHGLALPNPRAQEAL
LRSVYDRGRVHPDDLVYFEAHGTGTSVGDPAECEAIGRALGARRTDGDLPIGSVKSNVGH
LEPASGMAGLFKALLVLRHGVVPRTLHAEPLNPGIDFARWKLRPAVKELPLPSRPRPVVG
VNSFGFGGANAHAVLAPPPSPRPAKDGHDHGTLPVMVSAHTPVALAEAARRMAGRLRATS
DPEFYDLAHTACRRRTPHRYRAVVLATDREEAAAALGAVSGGRREGASASASVTSANTGR
TALVFSGNGSQWAGMGTGLLTDEPAFHDAVQRVDAALGPELGWSVHEALAAGAPGYDLRR
TEVAQPLLFAVQMGLVAVLRERGVRFSGVAGHSVGEIAAACTAGALDLATAARVVAARSR
AQAPTAGHGRMAAVGLPEDEARVEAERYGGRLTVAGVNSDRDVTLAGDPASLADLGEHLA
RRDVFFRMLELDYAFHSPAMDPIEGPLRALLGDLRTSGGSTPFYSSVSGGPLPGERLDAG
YWWRNVREPVRFADAVRAMREAGHDVFVEVGPHPVLAPYLRRLGHADGGPAVIRTCRRDG
DGPLEVRRAVAQLIAAGGQLDWDVYFPVPGRVADLPAYPWQRERHWNGAPGWWSRGAGED
GAGRGHPLLGTRLAALEPLWSGPVATARMPWLGDHKVGDTVVLPAAAYLEAAFAAAAETF
EGPVEVRNLQITRPLSLPWDDDSAEPRLQVSLSDEDQLLRIAARHETDTDWLLHARGRVR
RLLGTAPAPDRTASSPGPSTTTRVEKTEHYARAARAGLPYGPAFQVIGRLTVGTDEVVAA
YETGLPLGEFRAHPAILDGALQAGMPLMAGTADPDTPFLPTVIETARLWQSPPARGWIHV
TARERGPVDACWDVSLLDDDGHVTVELQGCRLRRFTAGGSQPVVRWETVLRAAAHPSLPH
PAPDAPLPAPPALADAAARWRAATGSTRRDERDRDVVRSLHEWAAHSIVAAIRQMLGQTD
REGAVGFSSEDLIAAGMAEKHDRLMRVLLPLAATHGLLRPVDDAGPGTTPYWRFRTDPAP
RDLFEKALARFPEHSLAFTVFGRCGLHLADVLRGRTDPRELLFAETDRHLIEQFYSRAPS
VQTQLDIVRQIVCTITGTWPRGRPLRILEVGAGTGGMTDRLLDVLPPESTEYVYSDVSAV
FFPRARRRFADRDFLVYRVVDIDRPLEEQGLAPGSFDLVLAHNALHVAKDVRRAVSRLVG
LLAEGGQLVAVEEHDLRSTAVCFGLLDEYWSFTDHELREDSPLLTALQWEDLLRTCGLGE
VCSVRVGEEENLPGSSVLLGRRATAPHAHPPEPQDRATGERWIVTAERPDGALAQALTGL
LVRSGADDVHRTGLPDDAEQWARAGQSGTGPLHAVIVLDGEQPPLVDADAVTGLAVRRTS
ALAAFARAYTRSGKPPATLSLVTRSGAPFGAPATPGFPGDAAPWAAARCLANEHPALAVR
RIALETGPDGDSGARRLALELLEPTADDEVLLTGGGRFVARSRSLGAARTTTSAGSAPYR
LEVRDPGPSHRLAWVPAGLPEPGPDDVLIEVRAVGLNYRDVLEANGMLQPAALRMSSGGQ
WTGLECAGVVRAVGARVTDLAPGDRVCALSTRAMASHAVASRQVVGRIPDDMDFAAAATL
PLVLLTVHYGLGHAARLGRGETLLVHAAAGGVGMAALHFARSCGSTVIATAGTPAKRDLL
RLLGVEHVLNSRSLDFAEHVRDRTDGRGVDVVLNSLAGEALVRSAELLAPGGRFIELGKR
DIESDSRLAMWLFADNRSFCAVEIGRLLEAGALPAEIVAGAFAEIRRGTCHALPHQSFPA
NRVDDAFRSLRHSRHVGKVVVTFDEPPLVERTPGRMALAPGGTYLVTGGLSGLGAATARH
LADRGAGGLALVGRRGPATPGAEILLEDLAARGVDTRVYAADLGDPRAVEEVLRAVESSG
RPLRGVVHAAMVLDDAPLAELSEEQIRAALRPKALGALHLDAACREPLDFFVCYSSATAT
VGTRMQANYAAGNLFLEALARSRRAGGRHGLTIALGAVSDTGYVAREGLEATLKRTGVGA
LSSAEACAALDELLATEAAVAVVGRSDWARVGAYLPATNVPRFEGMAPSTGRQGGDDPEK
LRQRLAGATADEAVDAVADVLSRAVADVLQTEPGRVDRQRPLDQLGMDSLMAAELVGVVA
RRLGCEIPAVELINAGSINGLAARALVRLGHGTSAGS
>A0A445NJP4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces netropsis|TrEMBL
MEPNDRAMAVVGAGCRLPGGISDLAGLWSALREGRDAVGEIPADRFDKARFVDAGALRPC
RSYTAAGGFLDDVASFDAAYFGIAPKEAEAMDPQQRLLLELAAEALDDAGMPAESLAGSD
TCVFVGISDPFYGLVQGTVEQYTNPYMMSGSTLSIAANRLSYCFDLRGPSMAIDTACSSA
LVALDRACRAVLDGTSRTALVGGVNVLGNPFSFSGFSHAGMLSARGRCAAFSADADGFVR
AEGGGVVVLKRLADALADGDRIHAVIAGTATNCDGRTHGLALPSPEAQEALLRTVYARAG
VDPDELVYFEAHGTGTLAGDPAEAQAIGRALGQRRTVGPLPVGSVKSNLGHLEPASGMAS
LLKALLVLRHGVAPATLHALPLNPGIDFAGLGLAPTVEPVELPRPAGAAVGANSFGFGGA
NAHVILTTPPAPPPRADHDGGTVPVLISARSAGALRELAARVSARLRESAPEEFYDLAHT
TTRRRSAHPHRAAVLAGGPAEAADRLEGIVAGAPTHGATARKAERDTVAYVFSGNASQWP
GMAADLLDAEPVFRTAVEQADAALTPHLGWSVAKELAQPHPPRWERTETAQPALFAVQVG
LVALLAAGGLRPAAVVGHSVGEVAAAHAAGALTLEQAARVIAERSRAQGTTAGTGRMAAV
GLPEQAAREELAPHADALEIAGINDERSVTVAGEPQALAALGAQLEARGVFFRDLGLDYA
FHSRAMDPLADPLRTALAGLEPSTARVPFVSTVTGRAFAGEGLTADYWWRNVREPVRFQD
AVAHVLAEHAGILVEIGPHPVLRPYLKRTDAVYVPTLHRDGDGPRETAAAVAALLAAGAS
VDWATHFPHPGRVTDLPAYPWQRERHWLGTPHDLVVRTSGTGRLDHPLLGERLPAPHALW
EGAIEPQLVPWLGDHKIAGAVLMPAAAYVEMALSAGRRALNRPVEVRHLGIGSPLPLAWP
DPGSARLQTSVTPEDGALTISNSEGRGTECHTVVRAEVRTLLGTASPPLDPEAVRARCPR
TVDGPDFYRTCHRFDLDVGPCFQLLRELRVGEDELLASYRHDDPSDAYTVHPVLLDGPFQ
ATVALVEQHMHDGHAYLPVMFDSVRVWRTPAPTGLMHLRRRSHTETEFCWDVTYADEDGT
VTAEIDGFRSRRAHNTRRTPLTVQHTVLRAAPHPALPAAPSPLPPPTELAAAAQERITRA
HDALRETGHDRFTAAVDESAAHCWAFAVAGLVPDRAAAFSLSDLVAGGLQPRHRRLIRLM
LPLMARHGLARPDDDGRWRLTGDEPRHETLLRALVEDHPAFITETTHLNAHLRHLPAVLR
DAAEAREALPDGDTAYEQLYEAAPDRRFTHRVMGALVREIVRRWPEDRPLRVLELGAKTH
ALTAALLPLLPADRTRYTCTDGSGAGFAGAGHRFAAHDFVEYRTLDLDTDPQTQGLCDGG
FDLVVADDALHTAADLAAALRRVRTLLAPGGHLLAVESHQPQRLGLLLGGTEAFWQRHDH
TLRPETVLMDRDRWPALLGECGFTGTVQTGTDDRSVLLAAADRLPAGEPDPPAAAPPSQA
PGAAWVVVTETPGGVPTAQALSGLLGGTDTTIIVTATGEPSACAAALPADTAGVVLLLGG
GEHRPPDSPAGTADDVVSLTTCRAAVLKSLAAACADRPATTRPALWLVTRPSGLFPAPER
PAHPADAAVWGAARTLANERPDLPVRRISLDPSGDPATDALRLAHELLAPTDEDEIVLTR
GGRFVPRETQRPADQPATDTARSLFTLDVRNPGLSRRLVWRQTEPLRPGPGEVLVEMRAA
ALNYRDPMRANGLLPPEAVEGTPLSRLLGTDGAGVIAAVGPGVMGFTVGDRVCGLMAGTL
ASHALMPAFAVCPMLDDMTYAEAATFPVVFSTVHHTLVDEARPLPGETVLVHGGAGAVGL
AVIQCARALGLRVIATAGTGTKRDLLRTLGVAHALDSRTLDFAPRILELTQGEGVDIVVN
SLSGEAIARSLDLLRPNGRFIELGKRDIFFNNPLLLRPFHRSITFLGFNLDSMVYDPVRG
PRLMHETTTRVASGQYRPLPHAVHPAARVDEAFRLLQHSRHTGKVVVSFDPLDEPVPVEP
LPGALSPDPEGTYLVTGGLGGFGAATAEWLADRGARHLALVSRRGSEAPEAAAVLERLAG
RGVRAIPYAADVTDEAAMREVIAAVDATAHPLRGVVHCAMHLDDAPLADLTDERFAAVLA
PKAAGADVLDRLTAGHDLDLFLLYSSVTATTGNLAQAPYVAGNTYLEALVRARRHAGRTA
TAIAWGPIAATGYVARNNLTATMTGIGFEPLAPAEAFTAAEPLIAADTAVAGIGRYRWGR
ARRLLPLLAGPRYAGLVPKDAGGLDDTREELLRSLTAMTPEDAVRAITDILARHLATVLH
TEPSELDPGRPLEEFGLDSLMGAEFILHAREYFDIHIPPSELMGSGRTLTHFARLIHDRL
GIHPDHRPQPSNASPAP
>A0A5B7VA51|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MNKRSARDDDIAIVGMACRLPGASTPEEYWTLLRDGVDAVGEVPAERRSLVPELSTNAVA
SGLNAPLRGGFLDHVDRFDAGFFGISPREASHIDPQQRLMLELGWEGLEDSGIVPAALVG
SRTGVYMGAMRDDFATVVHRRGLRNITQHTCAGLQRGMIANRLSHFLRLTGPSLTLDTGQ
SSSLTAVHMACESLQRGDCTLALAGGVNVILVPQSTVEATRFGGLSPDGRCFVFDARANG
FVRSEGGGLVVLKPLAEALADGDRVHGVIRGMAVNNDGGGRLTVPSGAAQQQVLELAYER
SGISPLEVQYVELHGTGTKAGDPVEATALGAVLGKGRSPDRPLRVGSAKTNVGHLEAAAG
IAGLLKAVLALRHRAIPPSLNFRFAPPGIPLEELGLRVQTALEPWHSSDGPRTAGVSAFG
MGGTNCHVVLTEAPEAGPTVPDERRLPDNRPHQSAAWVLSGRSEQALRAQARSLLAHADG
REEHTVADIAHSLATTRSALEYRAVVIASERAEFLEGLRALADGLSHNSLVRHAAGMPGV
TNLPSGSQTTDDKNGGSPLPALAAAYVRGEDVDWAKALASIGGRRVDLPSYAFQRQRHWP
DQADDGASDPAPRPAPTDQRITLESLPAPERQLVLLELVRTEVASVLEYSGPSDVEEDRC
FDDLGLDSLTAVELTERLSSATSLPLTSGLVYDHPTPRAVARFLDNLSFEPQASPPPPPM
PHAPAGVRDEPIAVVGMACRFPGGIHSPDDLWEAVAAGRDLLGDFPHDRGWDLDRLFDPD
PDQRGTSYVHHGGFLHDAAEFDADFFGISPREARAMDPQQRLLLEVAWETAEYAAIDPDS
LRGSSTGVFVGAIPQQYDTGVIQASEDLEGYIYTGNTTSVLAGRVAYNFGFVGPALAVDT
ACSSSLVAIHLACRSLRDKECSLALAGGVTVMSTPSMFTEFSRQRALAPDGRSKAFAAAA
DGTGWSEGAGLLMLERLSDARRNGHRVLAVVRGSALNEDGASNGLTAPNGPSQQRVLRQA
LASAGLSAGEVDAVEAHGPGTTLGDPIEAHALLAVYGREHAAEQPLWLGSVKSNIGHTQA
AAGVAGVMKMVMAIRHGVLPRTLHVDEPTRHVDWSSGTVRVLTEARAWPELGRPRRAGVS
SFGAGGTNAHVIMEEAPPDATTAVIHEPSARAVVLPWPLSAKGDQALSSLAGRLRRHLAH
DPERSPADIGYTLACGRSNLDNRAVLVAASPAEFQEGLAALEEAGSAASLVRGSGRRGGK
AVFVFPGQGSQWPGMATDLLKSSPVFRDSVQLCVDSFAAYLDWSVLDVLRGTDDAPPLDR
VDVVQPALFTMMVSLAAMWRAHGVEPSAVVGHSQGEIAAAHVAGALSLEDATRIVALRSR
ALLALSGQGAMAAVGAPADELRRWAERWPGLLGIAAVNSPMSTTIGGDPRALDELLTDLA
RENVEFRRLPGVNNAGHSAQVESLRGHLLDALSPVAPLPAAVPFCSTVTGALLDTRRLDA
EYWYRNAREPVLFEQACRALLDSGHGLFIEVNPHPLLHMALEETIADSGRAAAAIGSLRR
NDEATRRFLTSLAEAWAHGAPVDWRSVFTGTNARPVTLPTYAFQRQRYWCDAPAGRAEAT
GLGLDTSEHPLLGASVPLPHTDGLVLTGSVSRRSHPWLADHAVWDQALLPGTAFAEIAGA
AGREVGCDVVAELDLEAPLWLPDAGALRLQVVVEGPTQHGTRPFSVYGTSDADVGNQSWT
RHARGSVSHPSHGANPADAVPGPWPPSGSQPVDLTGAYERLHTLGYHYGATFRGLRRMWR
HGTELLAEVALPEEARSQGIGFGIHPALLDASLHAVLLETAGDSPTIRMPFSWHGVRLHA
TGSSTLRVRITRTGDDSIGLVATDSTGQPVVSVDSLTSRSVSRERLHADSPESRDSLFRV
EWTALPPGTVPSSTHTVAAIGTPGDPALRDAAWYPDMPSLAAALEDGAPPPSTVIASMPT
IADPALPGDVHTLIHHVLALLQAWLADDRFTHLRLTVLTHGAVATDTREDIASLPSAAVW
GLVRSAQAEHPHRFTLLDLDDHPANLDALSTALATAEPQLAARAGVLLTPHLVHALPASV
LTPPHHASAWRLDIPRKGTLDGLALVECEEHTQPLAEGQVRVGVRAAGLNFVDVIISMDL
FPGSAALGREFAGIVTEVGPMVSSFVPGDRVLGIVGIETGAIGPVVTADHRMMARVPEGW
SYEQAASMPIAYLTAYHGLVELAGLQPGEAALVHAATGGVGMAAVQLAGHIGAEVFATAH
PDKWQHLAQMGLDSDHVASSRTLDFGEAFLSATSGRGVGVVLNSLAREFVDASARLMPGG
GRFLELGKTDIRDASEIAGQYPGVTYQAFDVLDVGPEDIQHMLEAVLGLFADGSLQPLPV
TSWDVRRAPEAFRHFKEAKHTGKLALTIPQPLNPDGTVLITGGTGMLGGLFARHLVARHG
ARHLVLISRQGSQAPDAARLEQDLTDLGAAVTVAACDIADRDAVAGVLAAIPSEHPLTAV
VHAAGTLEDVVVTGLTPERCDNVLAAKADGAWHLHTLTRNEDLAAFVLFSSVAGVLGGPA
QANYAAANTLLDALAQHRAVQGLPAQSLAWGLWKQASTMSGHLTPRDVTRMVQSGLLPLG
DEEGLALFDTALRSGETVLMTAHVDTKTAHSDTSSPLLRNVLRPTVRQAVHGVPANVRSL
RERLACLAPAERDRSLLELVRQHASAALRLAAADRVPPERAFIDIGFDSLTSVELRNRLN
RVTGAQLPVSAIFDHPTPVALAAHVRDRLFPKGTQTRPAVLEELGRLEGLILQPQADART
AAAALTRLESLLARLREQQRSLALPAGPDLDEATATEVFKLIDDEFGLL
>A0A5B7V360|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MTRPSDTVVDALRASLKETERLRRQNQQLTAASREPIAIVGMSCRFPGGVASPEDLWRLV
ADGADAIGDLPDDRGWDVDALYDPDPDKRGTFYARQGGFLRDAGEFDAAFFGISPREALA
MDPQQRLLLETAWEAFERAGIDPATLRGTRAGVFVGSGYQGYGEGVRQAPEGVEGHLLTG
NTTSVMSGRLSYVLGLQGPAVTVDTACSSSLVALHLAAQALRQGECTMALAGGVTVMSSP
ETFVEFSRQRGLAVDGRCKAFAEGADGTGWGEGVGMLLVERLSDARRNGHKVLAVVRGSA
VNQDGASNGLTAPNGPSQRRVIRAALANAGVTAADVDVVEAHGTGTTLGDPIEAQALLAT
YGKEHSAERPLWLGSLKSNIGHTQAAAGVAGVIKTVMALRHGVLPKTLHVDAPTSEVDWS
AGSVELLTDARAWAERDGGGPRRAGVSSFGMSGTNAHVIVEQAPPVEEPAAEEASATPVV
PGVVPLALSAKTSDALRAQAARLHAHLLANTEVDADDLAWTLATARSRFEQRGVVLGRDR
DDLLAGLERLADGDALTGRALGGMVRPVFVFPGQGSQWAGMARELLDESPVFAERMRECA
DALAEFVDWDLLEELSGDRFDRVDVVQPVLFAVMVSLAAVWQAAGVKPAAVVGHSQGEIA
AACVAGALSLRDAARVVALRSLAIRELSGKGGMVSVPLPEQDVRELIAGWEGRIEVAAVN
GPAQVVVSGEPEALEELVAHCTGQDIRARTIPVDYASHSSYVEEIEAQILEALEGVSPQA
ADVPVYSTLTGSWLDATPMDAGYWYRNLRQTVLFEHATRGLLAEGHGLFLEMSPHPVLTV
PVQATIDATDSQAATLGSLRRDDGGADRLAASLAEAHVHGAELDWKALFPGTRTTVDLPT
YPFQRQHYWLRADSDAGDVTAAGLDDAGHPLLGAAVPLADGDGHLLTGRLSLRTHPWLAD
HAVAGAVLLPATAFVELATRAGDQVGCDLVEELTMETPLVVPGTGGVQLQLTVGSADASG
RRSLAFHSRPEAGPDAGGAEAEPWARHATGVLAVSTADTAPGASELAQWPPHGAEAVGVD
GLYEEFAAADVQYGPAFQGLRGAWRRGDEVFAEVSVPEDRRDEAGRFGLHPVLLDAALQA
AHLAQDGSRDSDGLDGSDGSRGDESGAPRLPFSWSDVSLYATGAKSLRVRLTRSGSDGDT
VSVLLADESGAPVARIGALVSRAVDAGRSLAAQRTRVPHLYRVNWVAAQTGGAVTAESWA
VFGAGAERVACALSEDGVDVTAYPALADLAAAVADGTAPAPGVVVAAPDLTAATDDTVAP
GTPTATDHTAAPGSPAAADGIAAAVHATTGAALALVQAWLADAHLADARLVVLTRGAAAV
TPDEPVPGLAHTAVLGLLRSAQSEEPGRFVLADVDDAPESLRALPAAYAHGEPECAVRAG
AVLVPRLTRDLGEPAEDPAALNASGTALVTGAPGGLGGLVARHLATVHGVRHLLFLGRRG
PEAPGAAELAAYMAESGVGIDIVACDAADRDALAAALARVPDEHPLTAVVHTAGVFDDGI
TSSLTAEQLDRVLRPKVDAAVNLRTLTAAADLDAFVLFSSVAGVLGGAGQGNYAAGNTFL
DAYAHALRGQGVPATSLAWGLWAERGGMAGQITADDLDRMTRSGIAPLATEQGLGLLDAA
LGLRAAALVPVRLDTAALRTAHGPHLPPLLGGLVHGPARRAVADRGGADGDTPALVRGLR
GLAADERERALLDHVRGQAAAVLGYASGDDVDAERAFRDLGFDSLTAVELRNRLKETSGL
RLPATLVFDYANPLALARHLASELTDGEASATTTTGAALPAPAQGHTDEPIAIVAMSCRF
PGGVANPEDLWRLVGAGADATSGLPEGRGWDTANLYDPDPDHQGTTYSRGGGFLHEAGEF
DASFFGISPREALAMDPQQRLLLETAWEAFERAGIDPATLRGSAGGVFVGASSQGYGESL
REVPDGLEGHLMTGNSTSVISGRLAYSFGLEGPAVTVDTACSSSLVALHLAAQALRQGEC
SLALAGGATVMSTPDTLVAFSRQRGLAADGRCKPFAEGADGFGVGEGIGMLVLERLSDAR
RNGHKVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRAALTNARLGAADVDAVEAHGTGT
SLGDPIEAQALMATYGKDRPGDREPLWLGSVKSNIGHAQAAAGVAGVIKMVMAMRHGVLP
KTLHAETPTTEVDWSEGAVELLTEEREWTAPETGRPRRAGVSSFGMSGTNAHVIVEQAPV
EEALPADAGDGPAPATAPSVVPGLVPLALSAKSENALRAQADRLRERLLAEADHDDTEKI
GLTDLGWSLTMTRSRFEHRGVVLGRDREELLTALERLAEGDATAGGVVTGRAVSGAGRAV
FVFPGQGSQWAGMARELLDESPVFAERMRECADALGEFVEWDLLEELGGDRFDRVDVVQP
VLFAVMVSLAAVWQAAGVKPAAVVGHSQGEIAAACVAGALSLRDAARVVALRSLAIRELS
GKGGMVSVPLPEAEVREVIAGWEGRIEVAAVNGPAQVVVSGEPEALEELVAQCVARDVRA
RTIPVDYASHSSYVEEIEVQILEALEGVSPQAAEVPVFSTLTGSWLDATPMDAGYWYRNL
RQTVLFEHATRGLLAEGHGLFLEMSPHPVLTVPVQATIEAAGREGAAVALGSLRRDEGGA
VRLLASVAEAHARGAELDWKAFYPGAGTVVDLPTYAFQRQHYWLTEDEAPGAAPVLAVDE
VEARFWEAVEREDLAELTAELEIAEDSAAGLGSVLPALSSWRRQRRERSALDALRYRVTW
KPLANSALPASGLTGRWLVVLPENAANHPWAAGSVAALTRAGAEVAELWLTSDQVTREAL
AERLRDLPGGDLPGGDLPGGDLPGGDLAGGDLAGVVSLLGLDETVVDGHEAVFAGLAGTV
ALVQALGDAGIGARLWTVSHGAVATGRGDRAVSPDQAQLWGLGRVVALEHPDRWGGLVDL
PPSYDTRTGARFAAALTGPGGEDQLAVRNTGVFVRRFAHAPLPEDRGAEPQWSPRGTALI
TGGTGAIGGHVARWLAREGVEHLVLTSRRGLQAPGAPELKAELEELGADVTVAACDVADW
DAVAGLLDELAADGRTLRSVFHAAGAGQEQPLHTMTTADVAAVLEAKVAGAAHLDELLDT
GSLDAFVLFSSNAGVWGSGSQGAYAAANAHLDALAEWRRARGLTATSVAWGLWGGGSGMA
GAEAEEALRRVGVTAMEPGLAVAALAQAVAYDETFVAVADVDWERFAPAFTSVRPSPFLA
ELPEVRRALEGPETAAAPAGTHAVAGSEWAERLAALPVPERERVALDLVRAHAAAVLGYA
GAEAVEPDRAFRELGFDSLTAVEVRNRLTAATGLKLPTTLVFDYPNARLLAAQLRREALG
DAPGTTGTRAVAPAPADDPIAIVSMSCRYPGGATSPDALWRLVSEGTDAISVFPADRGWE
TTGAAAYRAEGGFLYDAAEFDAAFFGISPREALSIDPQQRLLLEASWELFERAGIAPASV
RGHQTGVFIGSGYQGYGEGVQDLPEGVEGYLLTGSAGAVVSGRLSYAFGLEGPAVTVDTA
CSSSLVALHLAAQALRQGECDMALAGGVTVMSTPTAFDEFSKQQGLAADGRCKPFAEAAD
GTGWGEGVGLLLLERLSDARRNGHEVLAVVKGSAVNQDGASNGLTAPNGPSQQRVIRAAL
ANAGLTAGDVDAVEAHGTGTTLGDPIEAQALLATYGQERPAERPLWLGSIKSNIGHTQAA
SGVAGVIKMVLAMREGVLPQTLHVDRPSTHVDWSAGAVELLTEAREWAGRADVPRRAGVS
SFGVSGTNAHVIVEQAPVEESAEVVEPVAPVTAVPWLVSGRSEEALRAQAERLRDHITDD
SALDTVDLGWSLLSGRSPLEHRAVVLGQSREELLAGLETLASGGRGAVTGSVVEGRLGVL
FTGQGSQRIGMGRELYEAFPVFADALDEVCAHVDPWIERSLQSVMFGADADLLEQTGYAQ
PALFAVEVALYRLAESFGVRPEIVGGHSIGELAAAYVAGLWSLEDAAQLVTARGRLMQAL
PEGGAMLAVQATEADVLPLLSDRVGVAAVNGPAQLVLSGDRAVLEALEEALRDQGRKVKW
LKVSHAFHSPLMDPALDDFRKVAAKLTYQEPTLPVVSNLTGELAEPAELKDPEYWVRHIR
EAVRFHDGLKALQGQGVSTLLELGPDAVLTAMAHDTLTDPAAQTGLVGALRKDRPETDAF
LAALAQLHVRGVEVDWAPLYAPVETRRRVELPTYAFQHDRYWLTSGPAATRTGGVAADEV
EARFWEAVEAEDLESLSAELGGGADGGALGEVLPVLSSWRRQRRTASTLDALRYRVAWKP
LGHAPAARLDGTWLLVVPDGGADVADWAASVGNALGGLGAEVRTVVVPDAEGAGRDELAE
RLRKEAAAGDGALSGVLSLLAADEEPHAVRGGVSRGLAATVTLVRALHAADLGAPLWLAS
RSALTVGGADPAPRHAQAALWGLGRVVAVEYPRLWGGLVDLPETADARATAGLAGVVGGA
WTGEDQVAVRGSGVFARRLERAPLDTATAGQWTPDGTVLVTGGTGAIGGHVARWLAEQGA
RHLVLTSRRGADAPGAAELRAELEELGAEVTIAACDVADRDALAGLLDAIPDAAPLTAVF
HTAGVLDDGVLDGVTAERIATVFRAKVESARHLDELTSGLDLSAFVLFSSFAGLSGGTGQ
GSYAAANAALDALAEHRRARGLPATSVAWGAWGGGGMAADRARGGAVPPMEPELAVAALG
GALGQDPAVTVIADVDWEQYLAGGPALAPNPLFADLPEARALQERTARTDGGAADGTEPD
LARQLAALSGPERDRLLEDLVRTHAADVLGYPGPERVEPGRAFRELGFDSLTAVELRNAL
GTATGLPLPTTLVFDHPTPVALAAYLKAELAPGDGESAALLSQLDTLELGLAESAPSDDE
LATIAERLRVLLDRCTRGADDDEDAQVAEELESASDDEMFDFISKEFGIS
>A0A5B7V9K1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MTAPPYSPIAIVSMACRFPGDVWTPDELWELTRTGQDAITPFPADRGWDLASLTALDIRG
EPRSCTRYGGFLRHAADFDPGFFGISPREALAMDPQQRLLLETSWEAVERAGILPADLRD
SSTGVFVATAYQDYVARLRGTGPDIHGHWVTGNMGSVSSGRIAHVLGLAGPAVTVDTACS
ASLVALHLACQSLRAGECPLALVGGVAVMSTADYFIEFTRLGGLSPDGRCKAFSAVADGM
GLSEGAGVLLLEPLAEARRQGHPVLALVRGSAVNHDGGRSSLTAPSSWGQQQVIRRALAH
AQLRATEVDAVEAHGTGTQTGDPVEAEALLATYGQGRRADHPLWLGSLKSNIGHTATAAG
VAGVIKMVEALRRGVLPRTLHVEEPSYSVDWNTGAVRLLRDAIEWPHTQSPRRAGVSGFG
ISGTNAHVILEQAPVMRRPANRPRTVPSQPVPWVFSGRTPSALRGQAVRLRGLLRDQPDL
HLADVGLSLATSRTAFGHRGAVVAADAAGLAHQLDRFISQEVTQTPSKTQDADGVVFVFP
GQGGQWRGMGRALMASCPVFAEHMQHCAEVFEPWLEESLLDVVSGSSHGVRWNRVDLLQP
ALFAVMTSLAAVWRAYGVLPAAVVGHSQGEIAAAYVAGGLTLRDAARVVAVRSRELRRCC
GQGGMAAISAPLDEVERRLRKWDGRATIAADNGTAITVVSGDTQVVDALIAECTAANLHA
GRIPVDYAAHSAGVDVLRTPLLAGLTNLAPRTGDVPFMSTVTGQLLDMAELNADYWYRNL
RQRVRFAPAVRALVARGHRHFIEISPHPTLVLGIEQTAAEFDADASVIETLHRHEGDRFL
QAVAAAHSHGVAVDWISVFAGTGAQLTELPTYAFQRKRYWLEPSGTPPIPAGPKALHHPF
LTAVDKHPETGEVMFTGVLSLHIQPWLADHAVLGTPLLPGTALLEMAALAGSHTGYLRVE
ELTLETPLALLAEEKTELRVIVAAADDTAHRRLTVQSRRQGDPGDESWRQNATGLLGPEV
DTPGQAVAVTHWPPSGAEPVALEGLYQRLNDKGLNYGPSFRSLRAVWRLGEEFLAEVTVA
EAGSASVPWFTGHPAALDALFQAIFAGQLLPGHQAARSLLLPQAWSGVSIRTPRTRTLRA
RLRAIDGNCVSVVVTDDTDQTVLSADSLVLRTVAPDHLRSVVGDGALLHVCWCPVPPSTI
TPIGQLAIVGTDRSPGLPGHPRYPDLESLNRDTAQNTPGPQTVLWLRSATGLTAPEHVRA
EVNEVVHQLQDWLAADQTAATRLVIVTCRAVAATPGEDVQDLTNAAVWGLVRSIQAEHPD
RFVLVDVDTADTSYAAIPDAVATGEPQLAIRTGTPAVPRLRPITPEGVLAPPARTTVTSP
WRLAITAHDNRNELALIAHPDANCPLAPDQVRVAVRAAGLNFRDVLAHLGLAPGQAEVGV
EAAGIVMAVGSQVADFAPGDRVMGLVPGGFGPLAVTSHRMLTKMPGGWAFPRAASVPVAF
LTAYYALVDLAGLMPGESVLVHAAAGGVGMAAIQVARHLGAQVFGTAQPAKWDALRACGL
ADNHIASSRSIDFADRFLAATEDRGVDVVLNCLAGEFVDASLGLLPPGGRFIEMGKTDIR
DPDHVSRCTPGIRYQAFDLITNAGQERIAQMLATISDLFEQGIFQPLPIRTWDVRRAHEA
FRYMAQARHVGKIVLTVPAAWDPQGTVLITGGTGVVGSLIARELVASHGIRHLVLASRRG
HDAPGATKLACELRELGAQVNVVACDAAVRADLAAVLAAIPAAHPLTAVVHAAGVLKDGV
ITALTPQHMNAVARPKIDAALHLHELTRNHELSAFILVSSAAGTLGLAGQANYAAANAFL
DALAHHRQAAGLPALSLASGLWAPATGLTSHLGLGEMSRIRRAGIVPMPTADGLALVNRS
LLLDHAVTVPLRLDAAALGETPRVELVPPVLRDYVFLPSHSGTHTPRSETAPDLWGKARA
LAGMEQERVVLGLVQSEASTVLGHRSTEAVPADMTFQKLGMDSLTAIEFRNRLNAATGLR
LPVSLPFDYPTPLAVTRFLQAQLTGEDPDSPVVLATCEKPSSIYGE
>A0A5B7ULL1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MCESVRVDTSAVAVIGAAPAAPVRARQDPGVLAELTGVPLPADRAAEAESAWTACEDAGI
GTRDRADIDVFLAADDAGATEAAVADAGAIEADAAEADAAEADAAEADAAEADAVVTGAA
EASATGAGAEETGAEDAGKDGAGELARILGLPDPANPHRTGRTGRAPLAEAVAALRSGAC
ATALVGADGAFVVLARRDDARTAAFAYRLDDDHAWPDSVPALVEAALRAGRPGAGRTAPE
GPAVPVALSAHSPGALRARAADLHALLTAEPGLPVVDLAYSLATTRPALARRAALTGGDR
ARLTDELLALSEGRLVVPGPALTASALPAADPTDGIAFVFPGHGPQWLGMADELLAAHPV
FADQLHACADALTPYVDWPVLDVLRGTTDTPSLDRPDVGQPALWAMMVSLAALWRSWGVR
PGAVIGSSVGEIPAATVAGALSLEDGARAVALFSQAQVHLLERGVMVSVLASADEVRERL
TRYEGLDLAAVHAPGSVLVSGTEDAATALLADLAADGIRARSIDIRLAAHGRQVDAVLDL
MGTDLAPLTPRPTDVPIYTATTGARVDPLTLTADHWCRNLRGTADFQSATRAALAAGHRL
LLESSPHPVLTRAVQETIEDAAVEAAVVGTLRRGKGSADHLAAALAALHAHGALPDWEAV
FAGRGARAVPLPAYPLHTVPEAAPAASLADRLADAPDRPELLLDLVRTQLAAVVGPLGTA
ADVDAPLLELGLDSAGAVTLRNLLNAATGLNLPVSAVFDNPTCRGLAEHIGRIVLGTPTE
DDEPVTLAAVEDDEPIAVVAMSCRLPGGVRSPEDLWTLLSEGGDGLTAFPADRGWDLDGR
YDEDAERAGGYYQREAGFLHEAPQFDPEFFGISPREALAMDPQQRLLLEISWEALERAGI
DAAQVRGSRTGVFVGAMTMDYGPRLHEAPADLEGYLLTGNTASVASGRLSYTFGFAGPAV
TVDTACSSSLTALHVAVQSLRRGECPLALAGGVTVMPSQGMFVEFSRQRALAPDGRCKAF
SASADGFGLAEGATMVLLERLSDARRNGHPVLALIKGTAINQDGASNGLTAPSGPAQRRV
IRQALADAGVSAAEVDAVEAHGTGTRLGDPIEADALLATYGQEHTADRPLLLGSVKSNIG
HTQAASGVAGLIKMVLALRHGVLPRSLHITEPTPHVDWSSGAVSLVTETTPWPEVARPRR
AAVSSFGISGTNAHAVLEQAPDDIPATPETPADPPSAPVPFVFSARTEDALRAHASQLAV
AAEEFASADMADTLLSRSVFEHRAVVVGGGAEALAAVAHGAESARVAVGVARPAGKVAFV
FPGQGSQWLGMGVELAESSPVFRASLDACAQALAPYVDWSLYDVLNDAAALERVDVVQPA
LWAVMVSLAALWRSYGVEPDAVVGHSQGEIAAAHVAGALSLADAAKVVALRSKAILALSG
QGGMVSLAVTVEAARERIARWDGRISVAAVNGPGSAVVAGDADALDELMEACAADDVRAR
RVPVDYASHSPHVERIQEELADVLAGLEPVPAQVPMLSTVTGEWLTGTEVGAAYWYQNLR
NTVRFEEGTRGLLDRGVGVFVECSPHPVLTFGVRETLEAADAEAVVVGTLRRTDGDLDRF
LLSAAEAYVEGLPFDWRAAVPAGQHVDLPTYPFQRRRFWLEETARTTAGDDPAFAEFWSA
VERGDLAATLDVPADAPLTDVLPSLADWRRRSQERSAADAWRHRITWRPLAAAPAPALTG
TWLVVGSRAEAEHPWHTAAVEALRAHGADVLEADGSPESLRAVDVVPSGVLSLLALDERP
DPAAPVVPSGLSGTLALVRALGDAGIGAPLWLATTGAVSVGRSDPLTHPAQSQVWGLGLT
VGLEHPDRWGGLVDLPVTPDARTTTRLAAVLAGRADEDQLAIRASGVSVRRLTPAPAPAA
APPWRATGTVLITGGTGAIGGHVARWLAGNGAEHLVLTSRRGADAPGAPELAAELTALGV
RTTVAACDAADRTALAELFARLDADGTPVRSVFHAAGTVPSLPLADTETSDLAYALAAKA
AGAAHLDELCAGRDLDAFVLFSSGSAVWGSGELGAYGAANAFLDGLAQRRRADGLPATSV
SWGMWAGGGMVTGDLDDQLRRRGMRPMRPELAVGALATALATGETTLTVADVDWARFAPG
FTAARSRPLIGEIPDVVALAERDAAEQPAAGGALADRLAGLTEAESDRLLLDLVRGHAAA
VLGHDGADTVTPDRAFRELGFDSLTAIELRKRLTTATGVRLPTTVVFDHPTPTALAQHLH
TVVLGERHTAAAGRVAARAADEPIAVVAMSCRFPGGVGGPEDLWDLVLAGRDAIGPFPDD
RGWDTDRLYPADAEAHGRSRTLEGAFVYDAGGFDAGFFGIAPREALAMDPQQRQVLELAW
EAFERAGIDPSSVRDSLTGVFVGASPQSYAGTLEQAAPEMDGYRLTGDALSVVSGRVAYA
LGLRGPAVTVDTACSSALVALHLAVQSLRSGECSMALAGGAAVMVTPTAFAEFSLQGGLA
PDGRCKPFADAADGVGWGEGAGLILLERLSDARANGHEVLAVVRGSATNQDGASNGLSAP
NGPAQQRVIRAALANAGLTTADVDAVEGHGTGTRLGDPIEAQALLATYGQDRPARRPLLL
GALKSNIGHTQAASGIAGVIKMVQALRHGVLPRTLHLDRPSQHVDWTTGAVELLAEQRPW
PESGRPRRAAVSAFGVSGTNGHVILEQAEPAAPAPAAEPDGRLLAWPLSARDTAALREQA
VRLAAAVDERPGLSPVDVAATLALGRAALDRRAVVLGTVAPELQAGLDALAEGTDHPAVV
HGAPDGGTFAVLFSGQGSQRVGMGRGLYEAHPVFADALDEVFAHLDPLLDLPLRDVVFGA
DQAVLDRTEYAQPALFAVEVALYRLWTSWGLRPDALAGHSIGELAAAHVAGVFSLADACA
IVAARGALMQALPTGGVMVAVQATEEEIAPECSEHVGIAAINGPNSLVLSGSDLEVLALA
DRLKAQGRKVTGLRVSHAFHSPLMEPMLDAFRRVLEGVSFAAPRIPIVSTLTGTPVDAEE
LASPDHWVRHVRRPVRFADGVTALVAQGVTTMLECGPGGVLATMGQDSAPDTVFVPTLRS
DRPEADALTRAAAHLHVRGARFDLAAALGGRGARVDLPTYAFQHERYWLTAAVAPAGDGA
TAALGVATGDHPLLRAAVALPDSDGVVFTGRLSTRTQPWLADHGVGDRVLFPGTGFLDLA
LHAAGHCGLDTVEELTLHAPLVLPERGGVALRVAVGAETDGGRSIRVHARAEDADRDAPW
TEHASGRLTTGDAPATDLAAWPPEGATPMDVDDVYDRLTALGYGYGPVFRALRAAWRLGG
DVYVEVALEDPAGGEGFSVHPALLDAALHAPVLRALDETGSGPRLPFGFTGVRLHAVGAS
TLRVRWTPTGQDTMALAVADPAGRPVATVESLVMRPADLRKAAAPAADALFALEWVPVET
SGASPAGLAVLGTDDLGAHAPTVADFGALDGVTDLLAPCPRPSAADARTVRETVAWALAL
AQDWLADERTAHTRLVFVTRGAVATASPDPAQAAVWGLVRSAQTENPGRFALVDLDDTDD
SALALPAALASDEPQTVVRAGRVDAPRLARATTDGLLTPPADGPWRLSAAAGGSPDDLAL
VPHPDAAAPLAPGEVRVAVRAAGLNPSDVRTALGTEADAALGSEVAGVVTEVGTDVTDLA
VGDRVLGAATHAFGPLAVTDRRLLAPMPAALTFACAAALPQAFVTAHHALAGLHRGQPVL
VPAAAGDIGTAAVQLARHWGARVHTTGTGGDAEVLLTPPTAEAEALPDPLEFAYDSPQPD
PDRFQEILTEVLALFEAGALSPLPVRTWDVRRAPEAFRGLGQDLGAAKAVLTVPAPLDPD
RPVLVTGGLGTLGALVARHLVTDRGVRRLVLAGRKGLATDGAAELRDDLAALGAEVTVAA
CDVADRASVAALLASLDRPLGAVVHAAGVVDDGVLESLTPERIHRVFGPKVDGLLHLDEL
TRDADLSAFVVFSSAAGILGSAGQASYAAANTALDALVRRRHALGLPGVSLAWGMWAAAS
GMTAGLDGGDRARLGRSGILELPTEDALALLDAGTRDDRAELVPVLLDAAALRGQAADGT
LPPMLRGLVRAPARRATTAPAAATTAFADVIAGQSAAEREQTVLDLVCAQVAAVLGHSAA
THIDPGRGLQDLGFDSLTSVELRNRLTAATGLRLPSTLVFDHRSAAAITRHVLTLLPRTE
PEPETGVLAQLDRLESSLLALADDGTATKVDLRLRALLAKWSDARAGDADDDADIESDVS
AATDDELFGYLDNELETS
>B8LZ10|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MSFQRVIFLGGQGSRHSPSSSTRKLVDGGNPSLTLLLSACHSAFLEEVVASRSLLSIPEW
ANFEVSSSPESLLTLRPDQTRNPILEGVSLCANQLLAYLNYDPNLELSSHVAVAKSAIRT
AYWLGYRAAELAYKIAGEESQRLPWALSVIGMPEKTLETKVEDFNTLLDAPTLQNGSIRL
ANRFSQHAFSVVGLGSSLEQFRSRHLVGNTASSPIPVYAPYHAGNEGHNALEMVLRDLSC
GKSDFPSLADLKHPLWSCHDGRVLDAHSQLADSLLEYIISCILVENADLSNTWNNVVESI
KSYDESEVITIGAGARTLIASVNRDISSPQRTSFIDVPFIGIQSDTGLSTEFAIVGMSVN
FPSGLGKEQFWRTLEQGLNTVQKIPETRFKIDDYQPRRGQHGTNREMKARHGNFIDNPYG
FDHEFFNISPRDANSMDPQQKILLQGAVHAMDDAGYVPHVTPSYDPRTIGGYIGIATEDY
VQNLTRDIDVYYSTGTLRAFLSGKISYAFGWSGPSLVIDTACSSSMVSIATACRALAAGD
CSAALAGGANVITRPDMYIGLSKAHFLSDTGQYLKGAGLFVIKRLEDAILENDRIYGVIR
GIEVNQSGNASSITHPHSETQQNLFRKLLSSSGIDPTSISAVEAHGTGTQAGDGVESSSL
ESVFGGLSPVQSVYLTSIKGNIGHAEAASGAASLAKILLMMHHCTIPPQGSFKNLNPKLE
SLLSRTFRIATRSVEWKTRVSTPRRALINNFGAAGSNAALIVEEYQRNNIPPLTERTARA
AYNFILSAKSESALKALIKLYLEKLQMGPPSPAIEDLCYTVTARRQLYKWRSSLTVSSVT
DLIQQLEQNLTLHQCSAKSESLLVFVFSGQGSFYSGMGKQLLSTATVFREKVTECDQILQ
QLGLPSVIPDIDGTFVPAATSDFVLWSQIACFIVEYTLACLWLSFGIQPDVIIGHSLGEY
AAMAISEALSVKDALTIVVRRAQLMTKSCELGKTGMIACDRSASYIEKEILSANHLLSLT
IACDNSPTTSVVSGPLNDIDRLATLLEERKIRHKRLGVRLGFHSAALDPILQELNDLCHD
MPFHAPKFPLGSCLHGRLMQKGDLNPSYIAQQTRGKVRFAELVKSLHDKETQSPVFVEVG
PHPITSPMVKTIFSNPGSLFLPSLVKEQDAWVALSGALQQMSLRSMSVRWRSIFDGSEAE
IVDVPDYPFQTQSLFIPFGEIYAVTKYDTGVVKNIRPKSFHLLSEMQRESPTSVPSNFST
DLSFLSKYIHGHVVGKSPLCPASPDGVRAIFCSGWASWQPNTKINRTLARSAAYVKRQIA
HMQSKQAYTNVFRTKTLYNTIFPRVVSYSGDFQAIKELTVLEDGLEGYGTFQIPLKSRQG
GIITPVFVDTLLHAAGFVANSHVHQTDACICTKVEMTRILYQGISLNQTFQVYCSLLDCN
DGVLLGEAYAMTEEGVVVASVEGMHFKRLNLKFFQERLARQMVGGVSGQALSAVRMQSSG
SAKKTTTIESDWNMQTQVARQDDYESVVIDVIAQICEKSRVSINGLTNLSSLGIDSMMRI
ELAAPLRERFSDLDLDLDEMTNMENVQELQEYVKKQSIGASYTFPITSEGSSDETSFDEA
NDPPSSSSSSSDSPILPTSDGINQLLLIINKKCEVPVSEINLETTLGSLGVDSLMEIELQ
ETLQQHFGRSLPVEDTVFDLTIQELATYLGLNLTPKSQGTPLEEFQGSPNNPSYGISGNK
INYLQVTVSHEPALTQLQTSSEGFAPIGALSRWKITPIGGNVYAIKNPTLKETHWAKGLT
DMAEQYASVIIGSLKGPVILGGWSFGGVLAHEVAQSLEREGCRTLAVIMIDSPCPHNLEP
LPQPIVKHVLSAKELSTSAISVITAQFQHHARFLAEYSSQETIAQDVIPEGRKYFMLQSS
STIDTRRLCGADHPWLSDNQCREAALAQWERLLARQLTVLKIPGNHFEPFEPQNVSSLTE
SHCCSEGVN
>A0A0K2B0Q6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces ambofaciens (strain ATCC 23877 / 3486 / DSM 40053 / JCM 4204 / NBRC 12836 / NRRL B-2516)|TrEMBL
MSATNEEKLREYLRRAMADLHSARERLREVESASREPIAIVGMACRYPGGVASPEELWDL
VAAGTDAISPFPVDRGWDAEGLYDPEPGVPGKSYVREGGFLHSAAEFDAEFFGISPREAA
AMDPQQRLLLETSWEALERAGIVPASLRGTRTGVFTGVMYHDYGSHQVGTAADPSGQLGL
GTAGSVASGRVAYTLGLQGPAVTMDTACSSSLVALHLAVQSLRRGECDLALAGGATVLAT
PTVFVEFSRQRGLAADGRCKAFAEGADGTAWAEGAGVLLVERLSDARRNGHRVLAVVRGS
AVNQDGASNGLTAPSGPAQQRVIRDALADAGLTPADVDAVEAHGTGTPLGDPIEAGALMA
TYGSERVGDPLWLGSLKSNIGHTQAAAGAAGVIKMVQALRQSELPRTLHVDAPSAKVEWD
AGAVQLLTGVRPWPRREHRPRRAAVSAFGVSGTNAHVIIEEPPAAGDTSPAGDTPEPGEA
TASPSTAAGPSSPSAVAGPLSPSSPAVVWPLSAETAPALRAQAARLRAHLERLPGTSPTD
IGHALAAERAALTRRVVLLGDDGAPVDALAALAAGETTPDAVHGTAADIRRVAFVFPGQG
SQWAGMGAELLDTAPAFAAELDRCQGALSPYVDWNLADVLRGAPAAPGLDRVDVVQPATF
AVMVGLAALWRSLGVEPAAVIGHSQGEIAAACVAGALSLEDAARIVALRSQVIARELAGR
GGMASVALPAAEVEARLAGGVEIAAVNGPGSTVVCGEPGALEALLVTLESEGTRVRRIDV
DYASHSHYVESIRAELATVLGPVRPRRGDVPFYSTVEAALLDTATLDADYWYRNLRLPVR
FEPTVRAMLDDGVDAFVECSAHPVLTVGVRQTVESAGGAVPALASLRRDEGGLRRFLTSA
AEAQVVGVPVDWATLRPGAGRVDLPTYAFQRERHWVGPARPDSAATAATTGDDAPEPGDR
LGYHVAWKGLRSTTGGWRPGLRLLIVPTGDQYTALADTLEQAVASFGGTVRRVAFDPART
GRAELFGLLETEINGDTAVTGVVSLLGLCTDGRPDHPAVPVAVTATLALVQALADLGSTA
PLWTVTCGAVATAPDELPCTAGAQLWGLGRVAALELPEVWGGLIDLPARPDARVLDRLAG
VLAEPGGEDQIAVRMAGVFGRRVLRNPADSRPPAWRARGTVLIAGDLTTVPGRLVRSLLE
DGADRVVLAGPDAPAQAAAAGLTGVSLVPVRCDVTDRAALAALLDEHAPTVAVHAPPLVP
LAPLRETAPGDIAAALAAKTTAAGHLVDLAPAAGLDALVLFSSVSGVWGGAAQGGYAAAS
AHLDALAERARAAGVPAFSVAWSPWAGGTPADGAEAEFLSRRGLAPLDPDQAVRTLRRML
ERGSACGAVADVEWSRFAASYTWVRPAVLFDDIPDVQRLRAAELAPSTGDSTTSELVREL
TAQSGHKRHATLLRLVRAHAAAVLGQSSGDAVSSARAFRDLGFDSLTALELRDRLSTSTG
LKLPTSLVFDHSSPAALARHLGEELLGRNDTADRAGPDTPVRTDEPIAIIGMACRLPGGV
QSPEDLWDLLTGGTDAITPFPTNRGWDNETLYDPDPDSPGHHTYVREGGFLHDAAEFDPG
FFGISPREALAMDPQQRLILETSWESFERAGIDPVELRGSRTGVFVGTNGQHYVPLLQDG
DENFDGYIATGNSASVMSGRLSYVFGLEGPAVTVDTACSASLAALHLAVQSLRRGECDYA
LAGGATVMSTPEMLVEFARQRAVSPDGRSKAFAEAADGVGLAEGAGMLLVERLSEAQKKG
HPVLAVVRGSAVNQDGASNGLTAPSGPAQQRVIREALADAGLTPADVDAVEAHGTGTPLG
DPIEAGALLATYGRDRRDGPLWLGSLKSNIGHTQAAAGVAGVIKMVLALRHGELPRTLHA
STASSRIDWDAGAVELLDEARPWLQRAEGPRRAGISSFGISGTNAHLVIEEPPEPTAPEL
LAPEPAADGDVWSEEWWHEVTVPLMMSAHNEAALRDQARRLRADLLAHPELHPADVGYTL
ITTRTRFEQRAAVVGENFTELIAALDDLVEGRPHPLVLRGTAGTSDQVVFVFPGQGSQWP
EMADGLLARSSGSGSFLETARACDLALRPHLGWSVLDVLRREPGAPSLDRVDVVQPVLFT
MMVSLAETWRSLGVEPAAVVGHSQGEIAAAYVAGALTLDDAARIVALRSQAWLRLAGKGG
MVAVTLSERDLRPRLEPWSDRLAVAAVNGPETCAVSGDPDALAELVAELGAEGVHARPIP
GVDTAGHSPQVDTLEAHLRKVLAPVAPRTSDIPFYSTVTGGLIDTAELDADYWYRNMREP
VEFEQATRALIADGHDVFLESSPHPMLAVSLQETISDAGSPAAVLGTLRRGQGGPRWLGV
ALCRAYTHGLEIDAEAIFGPDSRQVELPTYPFQRERYWYSPGHRGDDPASLGLDAVDHPL
LGSGVELPESGDRMYTARLGADTTPWLADHALLGSPLLPGAAFADLALWAGRQAGTGRVE
ELTLAAPLVLPGSGGVRLRLNVGAPGTDDARRFAVHARAEGATDWTLHAEGLLTAQDTAD
APDASAATPPPGAEQLDIGDFYQRFSELGYGYGPFFRGLVSAHRCGPDIHAEVALPVQAQ
GDAARFGIHPALLDAALQTMSLGGFFPEDGRVRMPFALRGVRLYRAGADRLHVRVSPVSE
DAVRIRCADGEGRPVAEIESFIMRPVDPGQLLGGRPVGADALFRIAWRELAAGPGTRTGD
GTPPPVRWVLAGPDALGLAEAADAHLPAVPGPDGALPSPTGRPAPDAVVFAVRAGTGDVA
ADAHTVACRVLDLVQRRLAAPEGPDGARLVVATRGAVAVRDDAEVDDPAAAAAWGLLRSA
QAEEPGRFLLVDLDDDPASARALTDALASGEPQTAVRAGTVYVPRLERAADRTDGPLTPP
DDGAWRLGRGTDLTLDGLALVPAPDAEAPLEPGQVRVAVRAAGVNFRDALIALGMYPGEA
EMGTEGAGTVVEVGPGVTGVAVGDRVLGLWDGGLGPLCVADHRLLAPVPDGWSYAQAASV
PAVFLSAYYGLVTLAGLRPGERVLVHAAAGGVGMAAVQIARHLGAEVLATASPGKWDALR
AMGITDDHLASSRTLDFATAFTGADGTSRADVVLNSLTKEFVDASLGLLRPGGRFLELGK
TDVRDPERIAAEHPGVRYRAFDLNEAGPDALGRLLRELMDLFAAGVLHPLPVVTHDVRRA
ADALRTISQARHTGKLVLTMPPAWHPYGTVLVTGGTGALGSRIARHLASRHGVRRLLIAA
RRGPDGEGAAELVADLAALGASATVVACDVSDADAVRGLLAGIPADHPLTAVVHSTGVLD
DGVLPGLTPERMRRVLRPKVEAAVHLDELTRDLDLSAFVLFSSSAGLLGSPAQGNYAAAN
ATLDALAARRRSLGLPSVSLAWGLWSDTSRMAHALDQESLQRRFARSGFPPLSATLGAAL
FDAALRVDEAVQVPMRFDPAALRATGSVPALLSDLVGSAPATGSAAPASGPLPAPDAGTV
GEPLAERLAGLSAEERHDRLLGLVGEHVAAVLGHGSAAEVRPDRPFREVGFDSLTAVELR
NRMAAVTGVRLPATLVFDHPTPAALSSHLDGLLAPAQPVTTTPLLSELDRIEEALAALTP
EHLAELAPAPDDRAEVALRLDALADRWRALHDGAPGADDDITDVLSSADDDEIFAFIDER
YGTS
>G3J045|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Methylobacter tundripaludum (strain ATCC BAA-1195 / DSM 17260 / SV96)|TrEMBL
MNHASAPETELSPVKRALLALQTTRAKLEALEQAQKEPIAIIGMGCRLPGNIETPEAFWE
LLRDGKDTIAEVPASRWDSNHYYDPDYDAAGKIVTRFGSFLPQIQESDPQFFGISPREAI
SMDPQQHLLLEVCWEALEHAGLVPADLEGSRTGVFIGICNQDYSVLLMSREDIEIDAYMT
TGMAHSVAAGRLAYSMGFQGPCLAVDTACSSSLVAVHLACQSLRNRECDLAVTGGVNLIL
CPETSINFSRNHMLSPDGRCKSFDASANGFGRGEGCGLIVLKRLSDVVPGQDQVLALIRG
SATNQDGATSGLTVPNGPAQQTVIREALHNAGVAAEQIGYIEAHGTGTKLGDPIEIGALN
AVFGQTRSPQQPLIVGSVKTNLGHLEAASGISALMKVVLALKHEQIPRHLHCDQPTPFIP
WEEIPITVATQAIAWPASEKSRLAGVSSFGFSGTNVHIVMEEAPLTPEPTPQTEPAPERP
LHLLCLSARSAGGLTAQAARYAAHLDGVNQTALADVCYSANTTRSVFEHRMVLAAADAVE
MRGKLQRFCKSHDQRQPVETGANTAEPPRVAWLFTGQGAQYPGMGADLYRTQPVFRQAID
DCALHLDPLLGRSLTTLLCAADSADLHETAYTQPALFALEYALAQMWLSWGLQPDAVTGH
SVGEYVAACIAGVFSLEDGLKLIAARARLMQALPRNGAMAAVFADAGRVEQAIATLGNNP
LITIAAINSRSETVISGERQAIRTLLNHLTESGIRSRELTVSHAFHSALMEPMLAEYEQI
VRSVTLLPPRIRLISNLTGHFASTEVTDPAYWCRHIRMPVLFADGIATLRRQGITAFVEI
GPHPVLSGMVRADAPEQNTELYLPSLRKDQPDWEQLAQSLSELYLGGVPIDWAGFDRPYH
RRRTALPTYPFQRKRYWYNDSGITARQRHAPTSQLITLLQAGNADALAQHLQAQGELSAD
ELKLLPKLSNLLIRQHRDANANTDGLCYRPIWQEQARNAEPAMPPAGAQNRPWLIFSAGD
ESELAQSLQNLGQPCIRVTAGNAYAQTTADAWTVAADNADDYCRLLEATQPQTIVCVWPS
GLTAHYGEDELMQVILLARAAAGLQAPIKLWLITRDASNAGDRAPSSPFPSLLSGMARSL
FLEYPNLKGGVIDLEGNEIQALLRELLDSEGEDAISLRAGKRYVARLEAFQPIVAAPSRF
KADGAYLITGGLGALGLKTARFLAENGAGQLILLGRKGADENARESLDFIEQLGTQVRVV
QADSGDEAAMSELFKQLAADNFRLKGLIHAAGLLTARSLNELDRDCLHQVLAPKVRGAWT
LHRLTLDLDLDFFALYSSISSVLGTAQQAHYTAANGFLDGLAEYRRGLGLPALSINWGPW
QSGGMIDGETARHIADSGFNALSAPAALALFGRLLAAGQTRVAVLDADWPRLKSLYEVRG
RQPVLTLLGQSASTASVTGSSAVLDALRELAIRDRFDYLLNRLQEQVGAALRFDSNTLPD
PKRGFFDMGMDSLTAVELKGRIEAQLHRPLPPSVVFDYPNAEALAAHLLGLLFPGAQPDA
PAFAAIEESPSHSRAEIQQLSDAELAALIDDEFTSLTNQG
>G0Q180|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MSLRVLARMYADGEMSTTEVLAELGRRVDIPLSEGQRGLWALARMEPETYAYNVPVCFSA
ADVDTAALQAAFRDTLFRHPLLSATVRETDDGPRLVHADPDGFFVEEADISDVPSDRVPN
LLRERAKQPFDLAGDPLTRLAVLRRSASEAYVLLVVHHLVIDGVSGRLVTDTLFGSYRAR
VAGRDVPVERGSASFGEFVAWERDALAGERAKEDREFWVRELAGAEVLTGLPSQAALEPD
APHTGEVYTSRLPKERAAAITAFAASQGISPGIFFLAAFQTLLHRYTGSEDLVIGMPVAG
RPTERFDPIVGCFINTLPVRSRPKASEPFTSFALRVRSTVLDVLEHGNYPFHRIVGDLGA
RGVNPRSPLYQIVYNYQDSALSGHLAERARATGEADFELVDGLYQLGEYDLTVDVAPGDG
FLVNWKYHPDAFSADAVASMAEHFTTLVAGILDADGQAPLGELNLLDEEERHRVIEAGNR
TETDFPAHRTCWDLFAERAEATPDAPAVTCGERTLTYRGLADRSSALAQVLTRRGIGPGD
VVGVCYERSTDLVAALLAVMRTGAAYLPLDSRLPAERLSYMIEDSGAQLVVCHEAVMDGL
AAAGMPRARLYPTDRQDDQADRGRAAGETTTADAPAPSDPAPRAAYIIYTSGSTGRPKGV
VVPHPALTNFLLAMARTLDVTSEDRLLAITTHSFDIAALELYLPLITGGQVCVSDSATAA
DATLLADRIADWRPTLMQATPATWAMLVRVGWQNTEGVTMLCGGEALPEGLKDQLVARGE
AWNLYGPTETTIWSAAKRLLPEEPVTIGSPIANTRLYVLDRNLGPLPVGVTGELHIAGDG
VALGYHRKPELTAERFLDNPFAPGRLYRTGDRARRLPNGEIVVLGRMDNQVKLRGHRIEP
GEIEAVLDARPEIGRSVVLLEHVGLSDRLTAYCTGSGDAAVDTALLHAELARTLPAYMLP
AAYVVLDAFPLTPHGKVDRAKLAETARAVPLPAADGPVAGLDIERTVRGIFEEVLGSRDI
DRAAGFFDIGGDSFAAIEAVERINREFGRSLRPTSLFAHPSVATMARHLAGPPPAGNAPA
GQVPTGREGAGQAPAVRPVEPERSPGPSRATPAADDASLDDAIAVIGISCRFPGAGDHRA
FWSALVEGRSGGTSWSVEELRALGVPDELITRTGYVPQRSVVDGRAEFDAAFFDISPRDA
EFMDPQARLLLQHAWQALEDAGYRPEDVPATSVTTSTSTNFYQALLPALMANAAGPRVLA
SSETYAAWLFAQGGTVPTMISTKLGLHGPSMAVSTNCSSALSAVHVACRGLLAGDADQAI
VGAASLFSAGELGYVHQPGLNFSSDGHSRAFADGADGMSGGEGVGVVVLKRAGEAIAAGD
HVYCLIRGVAVNNDGGDKAGFYAPSVRGQADVIRKALDRAGTDPSTISYVEAHGTGTRLG
DPIEVAALTEAYRNYTDRSQFCGIGSVKSNIGHLDAAAGIAGLIKVALALQHGEVPRTLH
GDVPSTEIDWEESPFFVADRNLPLDGDGPARAGLSSFGIGGTNVHAVLEQAPAGARSAGR
PGPQAVILSARDGGQLGVLVRQLLEFLPGYRDAHGDLASLAYTLQVGRRAMAERVVFVAN
DVDGLIAALRDHVDRGGRGTVFAGTARRPEDQLLGLFDRPGELRDLVAGWVERGQWDRIA
PLWVNGVDIDWRAHHGARPPVRVSLPTYPFAGKRYWPAAGAVPVAPTVPDLPGTVPAPRG
PDPLDAASLLAAAAGTESVQTFLSGRASATDEMDGLSRPLVLAQLVAAGLLDGPVRRDLI
GQGVTPSFAPWLDHTVAVLLSHGELVREGGFLAPGEGAPGLEQAWRSWRAWTDAHAEDPE
LAAKTGLTERMVEALPAILTGRTKATAVMFPGGSFELVEAAYRGNATADYFNDVTAGAVR
AEADARRDGIRLLEIGAGTGSTSERVFARLKGRDLAEYRYTDVSKAFLIDAERRFADRVP
YVSFSTFDVEREPGSQGLTTGGYDIVVANNVLHATQDIVRAVRHARALLAPGGVLVLNEL
ARNDWWSHLTFGLLEGWWRFTDGRRIPGGPALSSDAWRAVLRECGFDTVELLAEPARALG
QQVLLARAGSPVPRRDPRPAATGSPQEHVRATVERILAETLKLTADELAADKPFADYGLD
SLTGVSLVQRLNESLGTDLDPSVLFENPSITRLTAFVVEEEGAALTAAHPEASPAPEAPA
VPEAPALSGPSAAPGRSVAPGLSPVPPPSAAPERSAARASAAPEPSAARRSSPVPEPSTA
SRASGGGREPVAIVGMSGRFPGARDTDAFWDLLASGHDAVSKVDRWDLASLGSVCLDGGL
LDGVDEFDPLFFGISGAEAVYMEPQQRLFLQEAWRALEDAGHAGESLDRDRCGIYVGCAA
GDYLDLTGPADYPGQALWGNMNSLVPSRIAYYLDLHGPALAVDTACSSSLVSLYLACQAL
WAGEVTTAIAGGVYVQNSPRLYLAASRAGMLSPTGRCRAFDQAADGFVPAEGVGALILKR
LSDAEADGDHIHGVIRGIGINHNGTTNGIAAPNGTSQERLIREIYQDFGIDPAGIGLVEA
HGTGTRLGDPVEFRALDRAFRGFTDAERFCSLGSTKASIGHAQAAAGVIGVIKTLLAMRH
EVIPGLPHHTETNSSVTLAGSPFFVHTEPRRWAAPEDGRRRAAVTSLGASGTNAHAVIEQ
PPGTPAAPRSRRDGPWLIVLSAATEHALRDQVARLARHCREHPDLDAGDVSHTLLLGRRH
LRHRWASVVRDLADLESRCAARLSGQDAPARSADAGLGALARQFLDGGAPDFAALFRDGR
HRRVPLPGYPFERERYALPVRAAVDDGSRGGGEVLTGDEFYLREHRVRGTGIAPGAMYLR
WAAAAAQRTASDAVHLRDVVFLRPLSVSGSPRALKVDLRADGDATRFTVSSTQSAGDEPV
LHCQGEVSAVRPTAAGTLDLPALLREMPSTGFDPQRFYAEWGERGIAYGPTFQGVVAVHR
GDDAVLAELRLPGAASGTADGLVPHPALVDSAMQCMRLLDGDDRVGLVFTIKSAEFLAPG
GTALWALIRRAEDTRGADRIDIDLATGDGTVCLRLRGIAGRTEQTADPADGSAERGAEPA
PDPVDAVTTLLPVWDPLPPDRSGAWPRSSDSVGVIAPPGPARDALLARLPGAHVVADPSQ
GTRDDLETSLRAVPELDQLIWVAPGAVDDRSAESVVEAQAAGPLHAFRTVKALLAAGYGD
RPLGLTLVTERAHAAHEAEAVDPAHAGVAGLAGSTAKEYPHWRVRAADVEAYDAPSLAAV
LDLPADPDGNLRVHRDGRWHGQRLMTVQPPSPASPTPSRLRQGGCYVIIGGAGALGTVIS
EYLIRRYRAQVVWLGRRPRDARVEAAIARASGPDGPAPLYLRCDATDLASLRAAKDETVR
RFGAVHGVIHSGLVFAGASLARMSEAQFEDVLRGKVDASVRCMQVFGGESLDFALFLSSI
NSYLKAIKQADYAAACTFLDSFALTVRRRHGTAGKVLNLGYCFNNAPAEGERGAVVGAQA
PLIQPDELTAAIERLCAGPVGGLTLMKFSPALNNRGIVLGDDEVVLPTAVPPDAVTAEAP
QPALAPGGELERIRARSAELTALTI
>F2UUA4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
TSGTTQHLTTTDHARLTRDGITPITTEHGTALFDAALGLNTPTTIATPLNLTTISKNPTT
HPLLRNLIPRRTPTTTVVATDQASLLTLVLENVATTLGHADAGAVDAGTAFQSLGFDSLT
AVELRNRLGAATGLRLPATVTFDHPSPVALAEFLHGKLSGQRTGRQVEARASADEPIAIV
GMACRYPGDVNTPEDLWNMLVSGSEGISEFPADRGWDLDAVYDPESSRAGTTYSAVGGFL
HDAGDFDPAFFGISPREAAAMDPQQRLLLETSWEALESAGVDPVSLRGSDTGVFAGAMYR
DYASRFTTAPKGNEDVVGTGNAGAVTSGRVSYGLGLEGPSMTVDTACSSSLVATHLAAQA
LRSGECSLALAGGVTIMATPDPFVEFSRQRGLATDGRCKAFSGDADGTGISEGVGLLLLE
RLSDAERNGRRILGVVRGSAVNQDGASNGLTAPNGPSQERVILQALANARLESADVDVVE
AHGTGTTLGDPIEAQALLATYGQGRPANRPLHLGSLKSNIGHTQAAAGVGGIIKMIMAMR
HGTLPRTLHVSQPTPHVDWTTGAVTLLTENQPWPDTDRPRRAAVSSFGISGTNAHLILEQ
PTPTPATPATTEPTPAAPATPLTTEPTPYPVSAKTPQALQAQITALQHHLTEHPELAPAD
IAHTLNHRTQFDHRALLLDTEVLASGTVGSGGLAFLFTGQGSQRTGMGQELHATYPVFRE
ALKAAIDAVDAHLGDQSLRTVFFGETSLLDRTLYTQTALFALETALYRLYESWGITPDHL
VGHSIGEITAAHVAGILTLPDAAKLVTARATLMDALPHTGTMTAIEATEEEITPHLDDTV
GIAAVNGPRSIVISGDDTAKIAAHFADRKTKQLTVSHAFHSHHMDPMLDDFRAVARTLTY
SAPRIPVVSTVAVDSDLTDPEYWVTQVRAAVRFHHAVQELETRGVTTFIELGPDGVLTAQ
AQQSAEGTFTAALRRGRDETTTVLTALGTAYVHGHTITAPQGDLVDLPTYAFQHERYWLV
PTGGGNATELGLGESGHPLLGGLLRLADGESTVLTGRLSPSSWLADHQVRGTVVVPGTAL
VDLALHAGELAGLSTLDELVIEAPMLLTEALQVQVKVVDDTVTIHSRTDADWTLHATGTL
GSTPVTPQEFTWPPTGSPLDVDELYVTLTQRGLEYGPVFQGLTQAWRDGEVLYAEVRVPE
HGFGLHPALLDAALHPSAATADTLALPFSWNGVTLHTREAGTLRVRLAPEAGDGLSLHAV
DENGAPVITVERLVTRPVGTELTAPTDGLFQLSWPQVTPTTRTTE
>A0A0N1FXB7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OV450|TrEMBL
MTAPLAHHEVPGGPWDDRFAETAGAAPEDDRDRSLDIAVTGMAGRFPGAGDIGSWWQALL
RGDVLTSRLDRERLLADGEPAGVLDDPDYVPVRGLLEDADRFDHDLFGISPREGELMDPQ
HRLMLEAAWTALEDAGCDPLTETRVTGVYASASSSAYLRAMLTSQTLDAAGVEEALRANE
PDYMATRIAYRLGLTGPALSVLTACSSSLVAVHLAVQALLAGECEQAVVVAAAVDFPQAG
HVHLPGGILSASGECRPFDASADGALAGSGVVAVVLRPAEEALAEGADPYGLIIGSAVNN
DGSAKAGYQAPSAAGQEAVIRSALAAADIGADTLGYLEAHATGTRVGDPIEWSAASSVLR
GLGAAPGRIAVGAVKANIGHLDAASGLVSLIKTLLVVREGRIPPVAGFHSLNPLLETDGS
PLYVPTGLLDWDGADGPRRAGVSSFGIGGTNAHVIVEQPPVRPPAADGDAPRDRVLMLSA
ASPDALARTARRLADRLPALASTPVGDIARTLAAGRARLPHRTAVTGRTHGELADRLRAA
AGSPSYAGKPAPVVFLLPGQGSQRPGMALPFRDALPGFAAALEECLAHFEPTLAARLRPA
LFDPAFPAGELARTELAQPALFCVEYAAATALTGLGLAPVALAGHSLGELTAAALAGVLP
LGEAAALVALRGRAMQACPPGAMLSLAMGGAEALELARQFAGAGGPLLELAAVNTAESAV
LAGPSDAVDAFQAWLGDREKVRRLQTSHAFHTSMIDPAVRELGQAVAQASLGRPRLPYLS
NVTGTLVAAGSEVEAGWFAEQARSTVRFAAGLAAIAEAHPDAVAVEVGPGRALSGMAEAA
GLTAVALAPGRSERPAEETSAALAGLWCAGLPLDAVALAGPGRTAHLPGYAFAGPRLVAP
AARVRPGTPAGAVPAPAGPTDGTGGTGATGGDGPPRPAAAGARATAPATPGEAVAARWTE
LLGRPELTPGSDFFDLGGDSLLVVRLARRLGDDLGVRVPVRALMTGPTLAEQTALVESLI
TAGERR
>A0A8B4DP51|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus subsp. abscessus|TrEMBL
MIFRTRVARRYRALATVENHDQLVAALRTVVAGTEHPLVVRNSEPATARRHGFVFPGQGG
QRPGMGRLFYDAFPSFRAEVERCADLFDKQFGRSPLSYLLDDQLPTNDSATVVQPALFTQ
MVGLAALWRTVGVTPRAVVGHSQGEIAGAYVSGVMSLDDAVTVVGTRAGIADEFPADDYA
MAVIATDRDTCEELLARNSGWAELSVINSPSMVGISGQRETVHQIVEHLTEDGVFARVIP
VRYPAHTSMIASIGAQIRHALTENLDAGEFTVSEIDCIGATLGTAISPEMPVDQYWFWNL
RNAVRFDRAVATAAAAHVDTFVELAEHPTLQLALRENLAALGSERTACVVGTSHRNATDL
GEFTANLAKIAVHDLDYNWDALRAEAPDRVSLPLRDFPNVQNNDIPLWLSYRADTSGVAV
PKQPIVTPEAERRVEMGNDSRAYPRLLREAWAKVTRRSMMPPRSYAFIDGTGDAGALVEA
LRDSAPNFGSSARIVTGTDESGIGDADTVVIVLPSPELLDDHEAAGAVARFFGNRTWWPR
LSSTVTGCWLVTVGGEQAIADDGPAHPVHAAIAAGFRCMGTEHPGIAFRHLDLTSDFATP
DKADNILAALQSAGESELALRADGMYAKRVLDIDQDGDESSRVVAPAHVVITGGTGKLGQ
EFCEHYARMGTRQITLISRSGETDAVTGRLDAIRRSTGAKVRALPCDVTDTAAVTALADQ
LRDTPADLIVHAAVDYSDTPLAEVTTNKFQDALRAKVIGISNVLDTVPRTDSCRVMLCSS
LAATIGGKGQLMYAAGNRMLDVLASTRRASGLDCTSIQWGQWTVHLDLGDAGIAKLAAAG
VHPMRPADALAVGMGRHHGNTLVGAFDLTQARAMLGVFGYGPLLSELEDNGGPVAPAETT
RPAPVVSENRSGHLVQLLAEVIGADHADSIDTAMPMVAMGLDSLQALEFRRRVQAELDFE
LPVQDLLGGASVDHVIDALTAQSR
>A0A0N0MM77|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OV450|TrEMBL
MTEPGNFVSGTDGVPTGHTAADAATESALVRDLGALPTAEQTHVLLDLVRDHALAVLRSK
YADAPDAPADLPVSVDPDRSFKDLGLDSVALLELQVRLNTATGLALPPTVAFDHPSPAEL
AAHLRTEVLGLSDRPEAPVRAVAVSDEPIAIVGIGCRYPGGVASPEDLWRLVSNGEHVRD
EFPADRGWDLDSLFSDDPSTPGTTYVRHGGFLPDAAEFDADFFGISPREALAMDPQQRLV
LETVWEAVERAGIDPAELRGTEAGVFIAAEPQEYAMRLHEAPDGLDGYLLSGNAPSVISG
RVSYVLGLAGPALTVDTACSGSLVGMHLAVQSLQRGECTLALAGGVAVMGSPGTFTAFSR
QRGLAPDGTVKAFAAAADGTAFAEGVGVFVLERLSDAQRNGHPVVGVIRGSALNQDGASN
GLTAPSGRAQQQVIRQALANAGLTGEQVDAVEAHGTGTTLGDPIEAQALLATYGRGRPAE
RPVWLGSAKSNIGHTQAAAGSAGVIKMLMAMRHDELPRTLHVDEPTPNVDWSAGEVRLLT
ESRAWPKGEEPRRAGVSSFGVSGTNAHVIIEEPPATDPAEPAADAGTAAPGAAPQAAPVL
LPVSAASGTALRAQAARLLARAEEEDAPAAADLGYSLATTRARLAHRAVVAAEDRDGVLA
GLRALAGGQESPHVFPGTADSGRLAFLFTGQGSQRAAMGRGLYDTQPVFAAALDEAIGHL
DLQLDRPLHEILFAAEDSADSALLGETVYAQATLFAVEVALFRLLESWGVRPDYVAGHSI
GELAAAHVAGVLSLDDAATLVAARGRLMQELPEGGAMVAVTASEETVAPLLASVADRVAI
AAVNGPASVVVSGDAEAVAAVVAQLEAEGHRTKRLRVSHAFHSPLMEPMLEEFRRIAEIL
DYSAPRIPLVSTLTGRAATAAELCSPEYWVRHVREAVRFDDGVRRLAELGATTFVEIGPD
PVLSGLGRDALDGLELPGGAPVFVSALRRGHDDVRQLSAALATAHARGTRVDWEAYYAGS
GARRVELPTYAFQRERYWLAAPVSRGDAAGLGQVAADHPLLGAVVSLADTGASVLTGRVS
PRSQAWLADHVIAGSTLLPGTAFVELALRAGEETGCDRLEELIMEAPLLLPATGAVALQI
VVEAAGDDGRRPIAFYSRDEDAPADAPWTRNASGVLTAAAAPSGEPFDATVWPPRGARAV
DTAHLYEDMAGQGYGYGPAFHGLKAVWQGADGVAYAEVALPACVADQASAFGLHPALLDA
VLQATDFASPEPVADGPRLPFAWSGVTLSAAGASALRVRITATGADSVAIDLAGADGLPV
ASVESFTVRPVTAEQLRPQAHDALFHLRWTSRPLPAAQQDAPAVVVHHALRDAAGEVPAQ
VRAVAEDVLGALRRWLDDEESATGRLVVVTRGALAVTPGEDVDLAQAPVWGLVRSAQAEN
PGRFVLLDSDGSLEPDELLRIAAALDEPEAAVRGGELYVSRLATLPSADPQPSPWEAQGT
VLITGGTGGVGAAVARHLVTGHGVRHLLLTGRRGADAPGVRETADELTGLGASVTVAACD
ASDRDAVAALLAAIPADRPLTAVVHAAGVIDDGLIGSLDAGRLDTVLRPKADGAWNLHEL
TQGLDLSAFVLFSSTATLLDGAGQGNYAAANAFLDALAATRRAAGLPATSLAWGLWTGVG
GMGGQLDEAALRRIERLGLQVLSPAENLALLDAALTATGGEAAVVPVRFNLRALQARAAE
VPSVLRGLVRPARRSAGTGAVPVEQSLARRLAGLSRAERGEALLDLVRTQVAAVLGHESG
DRINPTRAFNEMGFDSLAAVELRNRLSSAISLPLAATLIFDYPSPSALADHLAGKLGDPG
REARSAAPAAALVPADEDPIVVVGMACRYPGGVSTPDDLWQLVQGGVDAVGSFPTDRGWD
SDIHDPEPGKPGKSLSDKGGFLYDAAEFDAEFFGISPREAQAMDPQQRLLLEVSWETFER
AGIDPHALRGSDTGVFAGVMYHDWGLRLGPLPEQLAGYHGNGSLASVVSGRVAYALGLEG
PAVTVDTACSSSLVAMHWAAQALRRGDCGLALAGGVTVMSTPDTFIDMSRQGGLAADGRC
KSFGSGADGTGWGEGAGLVLLERQSDAERNGHRILGVLRGSAVNSDGASNGLTAPNGPSQ
QRVIRRALQDGGLTAADVDVVEGHGTGTTLGDPIEAQALLDTYGQERPQDGRPLLLGSIK
SNIGHTQAAAGVAGVIKMLQAMEHGVLPRTLFADEPSPQVAWEAGAVELLTEAVEWPAGG
RPRRAGVSSFGISGTNAHLILEEPPVAAPAEAPAEAPETAGGLLPWVVSGRTPQAVRAQA
ARLVTHLETLDEGDLAVTGRALATRRARLNERAVVLGETREELLAGLTALAEGATAPGVV
QGQVREGKSAFLFTGQGAQRPGMGRELHAAFPVFAQALDAVVAAVDVHLDRPLYEVMWGE
SAEDEALLNSTAYTQPALFAIETALFRLVESWGVRPDFLAGHSIGEITAAHVAGVLSLED
AARLVAARGRLMQALPAGGAMAAIEATEEEILPHLGDTVGIAAINSPRSIVVSGTEEAVD
AIQAQFTEQGRKSTRLRVSHAFHSPLMDPALAEFRAVAESVTYAPAQIPVVAGVHGELSE
DWGTPEYWTRHLREAVRFSDTVQHLAAKGVTRFLELGPDAVLTALTRTTLDTALDADTDA
DTPLVEPVLRRNRPEAPALLAALAQLHTTGTPIDWAAFYRAAEDRWADLPTYAFQHQRYW
LEGATAGGGAGLGSAGLESVGHPLLSAAIAAADSGEVVLTGRLSVDTQPWLADHDVLGSI
LLPGTGFVELAVRAGDQVGCDRIEELLLEAPLIVPARGGVALQVRVGTPDASGARSVSVH
SRGSAPDAPWTRHAYGTVVPGAPAPAFDLSQWPPAGATALGVDGAYDRLLERGYAYGPVF
QGLKAAWVRGDDVFAEVALPESAHADAARFGLHPALLDAAMHADLLGGNGAAEGATLLPF
SWNGVTLHAAGTSVLRVHIRRVRGDEVSAIMVADETGAPVATVESLVSRPVSEAQLAAAS
GGASAALHRVEWLRSAPSGAEAAGAAVWFAPVAAGEDAAARVRAVVPEVLAKVQGWLAGP
ESGAARLAVVTRGGVAVLPGEDADPAQASVWGLVRAAEAENPGRFVLVDVAAGTADPDAD
AAAALASGEPETAVRSGEVRVPRLTRIASPAPASPWSATGTVLITGGTSGLGALVARHLV
TEHGVRHLLLTSRRGPGAPNASAIVAELAELGAHASVAACDVTDRESLAGVLAGIDADHP
LSGVVHAAAVAGGGLVGSLTAEGFDSVLRPKTDGAWNLHELTRDAGLSAFVLFSSAGGSV
LAAGQADYAAANSFLDALATHRRASGLPATSPAFGMWGISTGLGGDLTDADLERMKRLGL
PALTVAEGLALFDAAVAGEDAVVLPLKTDAAALAARGGDLPALLRGKVRGTVRRTVQAQG
SETSELERRLAGASAQERDRIVLELVRTQVASVLGHASPDAIGPETAFREQGFDSLAAVE
LRNLLQAATGLRLPATLVFDYPNSRAVAGFVVDKLSATTAQAAPAAATAPRSAAASDTDP
IAIVSISCRFPGGVRSAEDLWQLVAEGRDAVGAFPADRGWDADAIYDPEPGTPGKTYAKD
GGFLYDAAEFDAEFFGIMPREALAMDPQQRLLLEAAWETFERAGIDPQTLRGSRTGVYAG
IMYHEYGSRLTDVPEDLAGYLGNGSAGSIASGRVAYTLGLEGPAVTVDTACSSSLVSLHM
ACQALRSGEITMALAGGVTVMPTPDLFVDFSQQRGLAADGRSKAFAGAADGTGWAEGIGL
LLVERLSDAERLGHPVLAVIRGSAINQDGASNGLTAPNGPSQQRVIQQALAAAGLTTADV
DAVEGHGTGTRLGDPIEAQALLATYGQGRDEDNPLWLGSIKSNIGHAQAAAGVSGVIKMV
EALRHGVLPKTLHVDEPSPQVDWTEGNVRLLTEPVEWPAGGRPRRAGVSSFGLSGTNAHV
ILEEAPQAQAPQAQERTQEPGPAAATPPAGAAAPVALTVSAKNAKGLPRQAEALRAHLEA
RPEQSLADVGYSLVASRAALEHRAVVLADDRAAAIRELAKLAGGTESADVVTGGRVDGAT
AFLFTGQGAQRVGMGRELHAAFPVFADALDAVVAAVDPYLDRPLYEVMWGESAEDEALLN
STAYTQPALFAIETALFRLVESWGVRPDFLAGHSIGEITAAHAAGVLSLEDAARLVTARG
RLMQALPAGGAMAAIEATEPEVLPFLSDEAGIAAINSPRSIVVSGTEEAVDAIQAQFTEL
GRKSTRLRVSHAFHSPLMDPALAEFHLVAESVTRHEAAIPVVAGVHGAISEDWGTPEYWT
RHLREAVRFSDTVQHLAAKGVRTFLELGPDAVLTALAQSTLDGQDAVVEPAVRKNRPEAR
TLLTALARLHTTGTPVDWTALHAGTGAQVVELPTYAFERRPYWLDAPAAAPAGDVTSMGQ
QPAQHPLLSAVVVSPEAGGVVLTGRLSVKTHAWLADHDVLGTVLLPGTGYVELAIRAGEE
VGCDVIDELTIEALMPMREDGGGLAIQVTVDAADATGRRSLAVYSRPDDGPADTPWTRHA
SGVLAPGAQHPPAPESFGVGTGVWPPQGAEEVDISGVYDYLTGQGYGYGPMFRCLRGIWT
RGKETFVEVSLPEDNLAVGTEYRIHPSILDGSLSATDFMDGRRPQDVGGTQLPFAWAGVT
LHAAGSSQLRGRITAVESHKSQGSDAVRIELSDLRGTPVATIDSLVVRPVTAARVNAAAA
AGQGERPSMFHLVWNQLPLGASHTATADRWALLGGGADHTFGEGMAVYPDLAALAAALDG
GAQLPEVVLLPVPAGGGEVPDAVRSVTGAVLDVLRTWLDEPRFGRSRLAVVTRGAVQAKD
TDTVDLAQAPVWGLLRSAEEENPGRFLLVDTDGSAAAHQVLPAIVATGEPEAAVRGSEVK
VPRLARIASSQVASELPWSAEGTVLITGGTSGLGAITARHLVAEHGVRHLLLTSRRGPDA
PGAEELRAELAGLGAEVSVVACDVSDRGAVDALLAGVSAEQPLTAVVHAAALMDNALTAQ
LTAEQVDAVLRPKADAAWHLHEATLGLDLSAFVLFSSCAGLVVGAGQGNYAAANRFLDGL
SAHRRSLGLPATSLAFGLWETKTGLGGGVTDSDLGRMKSLGLPALPTAEGLQLFDEAMTL
DEVMIAPIRVDNAGRGADPGAAPVLLRDVLKAEPAAQQRQEVRAPAVARAAAAAAGSGSL
EERLARMRPADREPAVLDLIRAQVAAVSHSDPDTIDVNKGFTDLGLDSLAAIDLRNRLQT
ATGMRLPATMMFDYPSPVVMAEFLLEEILPAIEDVAEPEPAAVADRDDHSIREALSSIPV
AALREAGLLDALLRLAGPAGQQGAPAAPAASGTPAAPQTADRSEEIKSMNIDDLVRAALA
SAEPNSNEG
>A0A0N1HJH0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OV450|TrEMBL
MPDQDKLRDYLKRATADLQSAKRRLREAEAREHEPIAIVGMSCRYPGGIGSPEDLWDLVA
SGGDGITGFPLNRGWDVDGLYDPEPGTPGKSYAREGGFLHDADRFDADFFKISPKEARET
DPQQRLLLETSWEALERATIDPHSLRGSRTGVYAGVVYHDYPSDGGIGGLGSIASGRISY
TLGLEGPAVTVDTACSSSLVALHWAVKALRAGECTLALAGGVTVMATPTSFVGFSQERGL
APNGRCKSFAASADGTGWGEGAGMLVVERLSDARRNGHPVLAVIRGSAINQDGASNGITA
PNGPSQQRLIEQTLAGAQLTADQVDAVEAHGTGTTLGDPIEAQALLATYGKGRPADRPLW
LGSIKSNIGHAQAAAGVGGIIKMVEAIRHGILPKTLHVDEPTPKVDWSAGNIRLLTEAVA
WPETGEPRRAAVSAFGLSGTNAHVIIEAAPAEDAPAAEDADPSAPAAATGAAAPALLPLS
AKTADALRAQAANLLDHLAGRDAAGDEASVRDLGHSLAVTRAALEHRAVLLAADREELVR
GLTALAEGDTPGDAARAVAEPDVRTAFLFSGQGAQRLGMGRGLHAAFPVFAEALDEAAAA
LDAHLDAPLKHVMWGEDEEALNDTAYAQPALFAVETALFRLVRSWGLRPDLLAGHSIGEI
SAAHAAGVLDLADAARLVTARGRLMQALPAGGAMAALQATEEEVRPHLTDGVGIAAVNGP
RAVVVSGEQDTVRAIAAHFGQEGRKTKELRVSHAFHSPLMDPMLEDFRQVAQSVTWNEAR
IPVVSNLTGRPAGPGELQSADYWVRHVREAVRFSDALRSLEADGARILLELGPDAALTPM
AADSLTAESGALAVPALRRGRDEARTLLAAVAQAFARGAALDWDALTGGPARRLPLPTYP
FQHRSFWADTVPATPGLLAAGAGGGAADPADTAFWDAVEHADADTLAGRLDIAADPLHEV
LPALSKWRRRHRDAYTLDSWRYRVVWQPAPDTLPAAALTGTWLVAVTPETAADPRPAAVL
AAIADAGATPETVEVDGPDRAALTEALRGRTAAGVLSLLSLDERPHPGHPGLSRGLAATI
TLVQAHGDAGLTTPLWLATSGAAAVAGSHEVTSVAQTPLWGLAGALALDLPQTWGGIVDL
PAAADAGSARHLCSLLTGTSGEDAVALRPQGVFVRRLVRAPLAGQEPRRTWQPHGTVLIT
GGTGGLGAHVARTFAAEGAGHLLLTSRSGRAAAGTDELVAELTALGARVTVEACDVTDRA
SLSRVLDSVPEDQPLTAVIHAAGAMQRIAPLADLSLEEFAEVGHAKVAGAVLLDELLADR
PLDAFVLFSSGAAVWGSAGQSAYAAANAHLDGLAHRRRAQGRTVTSVAWSSWDGGMVDAE
LGAMMRRIGAPAMRPSVAVGALRQVIEHEESHLVVAEFDWERFVPTYTLARPRPLLNALP
EVRDILAGAAGPADAGGGSALVASLAGKPEAEQTRALLDLVRGKVAALLGYDSPAELEPT
RAFEDLGFDSVAAVELRSRLSEATGANLPSTMVFDYATPAALAAFLRTELFQDGDGGPAD
VLTELDRFEELAASLDIEQIRSSRITSRLQALVGRLTDLQGTGEMVRDQLESASADDVFA
FIDRELGLA
>A0A2X3MX50|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. Ea1.12|TrEMBL
MTVPPDRLVEALRAAMKENERLRGLIAQAGEPIAVIGMACRFPGGVRSPDELWRFVAGGG
DAITPFPTDRGWDTSALTCFGGGFLHDAADFDPEFFGMSENEALATDPQQRLLLETSWEA
FEHAGIDPRSARGSRTGVYFGVIFHDYGYRLRPPPPGIDGYAYFGSAGSIASGRVSYTLG
LEGPCVTLDAACASSLVGLHLAGQALRRGECSLALVGGVSVLATPELWEETTRHGQGLAP
DSRCKSFAAAADGTGISEGVGVLLVERLGDARRNGHPVLAVVRGSAVEQSGATNGFTAPS
SASQERLIGRALADAGLAAADVDAVEGHGTGTPVGDPIELAALLATYGRGRPAGRPLWLG
SLKSNLGHTQAAGGAGAVIKMAMAMRHGVLPRTVHVDAPTPHADWSEGAVALLTEAVPWP
DTAGRPRRVGVSSFGANGTLAHVILEQDQPLPADAAAGDGTAGRAVDRLVVPWPLSARSA
PALRAQARRLLDLVTERADLLPADVGFSLATGRSAFAHRAVLVADDRAEFLRGLTVLAAG
PPESTDAALDGRAGAGLVLVLPGGGGWGLGAGRALADAFPAFGAEWATLRGALTGAALQT
APQVALQVALCRLLESWGVRPDAVVGHGAGEAAAAYVRGALSLDDLRALLAAGARSASPG
CRVPPGTANVLVVGRDEAGVDIPRGAKSWVLLPPGRAEIRAVTEASATLYEWGQAVDWRA
FFAGTGARRVDLPTYAFQRRRYWLEAADPGPTPAPGLPAAPAAPGVQR
>A0A1K2G1H7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. F-1|TrEMBL
MSAVAEVFAEQGRKTSRLKVSHAFHSPLMDPMLEEFEQVVRGLSFNEPRIPIVSNLTGRL
AESYTPEYWVRHVREAVRFADGVRTLHELGVTTFVEIGPGSVLSGLAQGCVDDIVTIPVL
RAGRSEPQAVVTALAELHVQGTEVDWHAFFPGARRVDLPTYAFQQQRYWLEAPEAETAAV
DAVDAGFWASVEREDAQSLAATLELSPDELNVVIPKLSAWRRRRREQSAVDDRRYRVVWQ
PLNGLSAGDLSGRTWLFAASEDDEWAQTVRAALAGRGARLVPLPVAADADRATLAEELTR
ALEGAGAPDGVLSLLATDETASPEHPALARGLALTVALAQALGDTGVEAPLWCVTRGAAA
TGRVDDAPLSAVQHQVWGLGRALALEHPARWGGLIDLPAAVDERAAGRLAAVLGQGTGTP
HGREDQVAVRATGVFTARLAHAPSGTATARPWAPRGTVLITGGTGALGGHLARWLAGAGA
AHLVLTSRRGADAPGATALKAELEELGTRVTLAACDVADRDAVAALLAGHTFTSVFHAAG
VEQFGPFDALTPDDFARTVAAKARGAAHLDELLGDRELDAFVLFSSIAGVWGSGQQTAYA
AGNAFLDGLAARRRARGLTATAIAWGPWADGGMVSGTDEEQLRRRGVLTLPAALAVTAVQ
RALDRDDTAVVVADIDWARFLGPFTLARPSALLSELPEVLGARTAAPAGTATGTAPLADR
LAGLPEPERVRTLTDLVRAHVAAVLGHSSAAEIEPDRAFKDLGFDSLTAVELRNEVNTAT
GLSLPATLVFDHPNATALARFLQSELLGTRPAAPQERHTAATDEPIAIVAMSCHLPGGID
SPEALWNLVLSGGDAISEFPANRGWDVDGLYDPDPERPGKTYARDGGFLYDATDFDADFF
GISPREALAMDPQQRLLLETSWEAFERAGLGLAQLRGSRTGVFVGMAYQGYGADVRHTPE
GVEGHRLVGGASSVVSGRVAYTFGLEGPAVTIDTACSSSLVALHLAMQSLRGGECTMALA
GGVTVMASPNVFVEFSRQRGLSPDGRCRAFGAGADGTGWSEGAGVLLVERLSDAVRNGHE
VLAVVRGSAVNQDGASNGLTAPNGPAXXXXXXXVR
>A0A8H2QRG3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Burkholderia pseudomallei|TrEMBL
MAQVAFLFPGQGAFYAGATRALSGAYPVVQRAMQAIDAVSVRRLRRPLLATVWDGHIGAE
DLLQHAPDLLQLAIYATSVSYFEALRARGVRPDVLVGHSFGEIAALTCAGAFSIETGAEI
VCDRIDALRAAAPADGRMAAVGASPDAVRAHLAACFRDARAGRVRIAVENHVSQTVVSGA
CEYVDEFRAYCARNNISAQVLNSPYAFHHEDLENARIEFGRRLKAYKNKALEYPVYSPIL
NRYYTAADDLGACLARHLVLPVRFGDGVARLKAAGIGAFVECGALNALSRISVRALGPGA
VKTFPGASSAGGELAGLENVLAYFNGGSVMNDDIRASNLQLDFDEFWRNSGPGIVDKIKG
ELKRFFDARGLQATPAPQIVADHGVAAGFAGGLTAGAADYAPKVAAGVSSAAAPVAAPVV
AAAAPAAPLAVAPAAPVAQAAAVPAASARVPRDRLFVELVAIYAEAMEYPVEVFTETVEL
EAELGIDSVKQTEIIQRISARYGLPPLPANFRAGDFKAMGQIVDFVYEHQGEAALVTS
>B2J0Z0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MNDSIASTPKTGSEIAIIGIAGKFPGAKNTDEFWQNLQRGVESISVFTDEELLASGIDAA
TLKNPKFVKARAVLEDVELFDASFFGFNPREADITDPQHRLFLECAYIALEDAGYDSENY
QGSIGVYAGASFSGYLLNVYLNEDIIKSIDYHQLAIAGDKDYLTTRVSYKLNLEGPSYTV
QTACSTSLVAVHLAAQSLLNGECDMALAGGVSINSSGKTGYLYKEGGIGSPDGHCRAFDA
QAQGTVGGEGVGIVVLKRLDDALADGDTIHAIIKGSAVNNDGSFKVSYTAPRIDGQAKVI
RTAQVVAEVEPETITYIEAHGTGTSLGDPIEIAALTQAFRATTEKKGFCAIGSVKTNIGH
LDAAAGVTGLIKTVLALKHQQIPPSLHFQQPNPQIDFANSPFYVNTTLTEWTTNGIPRRA
GVSSFGIGGTNAHVILEEAPAKEQGSRGAGEQGRKYHLLVLSAKTESALETATANLANHL
KQHPNLNLADVAHTLGIGRRAFDHRRIVVCQDMNDAVKVLSTSDSQRVFTHYQQPCHRPV
VFMFSGQGTQYVNMARELYGSEPIFTLTVDSCCELLQPHLGFDLRHVLYPDEAQNAKATL
ELQQTSVAQPALFVIEYALAQLWMAWGVQPEAMIGHSIGEYVAATLAGVFSLEDALMLVA
IRGRLIQQLPTGEMLSVQLPEQEVQPLLDSQLSLAASNGPSYCVVSGATEAINRLQQQLE
AKGVACRKLHTSHAFHSQMMEPILQPFTQQLQKLQLHPPTIEFVSNVSGTWITVAQATDP
NYWVKHLRQTVRFSEGMTELFKIQERIFLEVGPGRTLSTFAKQHHQEKLVVLTSIRHPQE
QQSDVAFLLNSLGQLWLFGVKVDWSGFYANEQRHHIPLPTYPFERQRYWIELQKQPHLGG
QSQPKATATELGKSLVEVCRVKARASIATLDAPTYLLNKQYLDRLCTAYINLALQRLGAF
NNSNEQYSSKELCEQFQIIPRYRQLLYRFLDVLVEQGHLKQEKDLFTNLVPCSIDSINTL
VEEVKIRYVDTLHELNIVRECGENLPNVLIGEKEPLELFFAVKDHKPKPEANSELPLNTH
LQGIIRTGMEQVVKSLPSDVNLRILEIGGGQGIATAELLPVLPSERTNYTFTDVGGLFLN
QAKQQFSAYPFVEYHFLDIEKPPTAQGFNSHSFDVVVAVNVLHVTQNITKTLEHVRSLLA
PGGFLLLWEITQPQLNFDITDGLLMNPLEDEGRNRGNPFLSQEQWQDALRSHGFVEVAAV
SETEAFGEQILVAQTAVSVTDSAPTAFTVTKQKAPKEQYQDLLSKKPDIADWFYIPSWKR
TMPPQPFQPGFGITQPGCWLVFVDEFGLGERLVKQLVLENQDVITVKVGEQFQQSSEYSQ
YTYTINPEKEDDYNTLLKGLRTLGKIPRRIVHLWSVTSNSYTNSAIEALGWSSLLFLGQA
MSDDKALRVYAENNQTDAVEIAIVSNNLQEVTGSEMLCPEKALVLGACKVMPLEYANINC
RSIDVVIPESESGEEQLIKALIAELTTYTSDQVIAYRGRNRWVQDFEPVQLHGTVAGNLL
REQGVYLITGGLGGVGLLLAEYLAQTVQAKLILLGRSAFPDQDKWSEWLSTHDRHDSISQ
KIQKLQAMKTLGAEVMVVSTDVTNLEQMSAVLKKANQRFGEIHGVIHAAAVYGGGMMQLA
TKETVASAIAPKVQGTRVLETLFQESKLDFFVLCSSLSSFAGTSGMVDYTAANAFLDSFA
QYSAAKYGTWKFIKSINWDRWNNVGMAVPVEARHQQITGKELIAGMTAFEGIEAFKRILC
SSTVPQVIISTQDFLSLIKPKESVESLEEKLAQLSQYKSTHPRPNLANTYVAPNNEIERN
LADIWQQILGIEKVGIHDNFFELGGDSLFATQLVSQLCKVFQIELSYKGFFNGPTVADLA
EVIVQKMAEQTNSEELAKALADIEQLSENEVYAIITSQN
>S5XLM9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Paracoccus aminophilus JCM 7686|TrEMBL
MSDEMAVLESAVAIVGLSARFPGCADHREFWQNLRAGKETVRTFQRAELLAAGVSPDLVD
RPDYVARKGILDRLEAFDHDLFALTKGEAAQLDPQHRLLLELAFHAFEDAGYDPGEYPRT
GVFCGVGLGSGMLGRALAQAGEVSEQDLFALYVSSEKDFVATRIANRLGLQGPALGVQTA
CSTSLVAVHLAVQSLLSGEVDCALAGGASASTPSVRGYRYSSDFILSKDGHTRPFDAEAS
GTLFSQGGGMVLLKRYEDALRDGDRPYALILGSAINNDGSDKVGFTAPSVTGQAAVIREA
LAVAGVAPETLGYVEAHGTGTSLGDPIEVRALTQAFGVAQPGSCAIGSVKGNFGHTDTAA
GIAGLIKTALCLHNQSLVPTVNYTTANPKIGFQDTPFFVQGDFAPWPARDGVRRAGVSAF
GIGGTNAHVILQDAPPQFAQRSACGAKTGSAPTDICLPLSGRSAAAVVESAQGLRAVCES
AEPAFGDLERTLRARREHAEYRHVVFAKDHGGLRQALSAVATQNLEPVTPRPVVFLFSGQ
GSQFPGAGRELYTQYPVFREQFDHLATIAGRSLDVDLRQLAFGQERGRMDETWLTQVLLL
SSEYALAKQIMAWGVKPAALLGHSIGQWTAAALAGIVSAEDALHLTIERGALLWQQPRGG
MLSIPLSAEDCLAELKDSGLSLDLAAENGPRASVVAGTKAELTRFQERLEAQGITSRQLR
TSHAFHSRLIDGAVAPFAAAVGGVTRKPPEIPIICNVTGEWLGDAQAVDPGYWADHIARP
VRFARGIETLQRHADFCYLEVGPGTALSQLARACLPLPERRWVASSMRGPDQPSDREALL
QGLGRVWEAGQPVDFAQIRPLDQARRLHLPGTRLEGEAPPAAEVEVLGQSWQALALARPD
AKDGTALASRQGLAALILAADADMEQAGRAALHPVVGKVHAVTLADLGDRDPVAALTDLL
DQLRRDGVSLQLVVDLWPLSDELRLEPLVQRALALAAALTAHDRPAFWWTLARPAESAKP
PLQAWLTGPVVSAASECRGLAARLVTLDTQSSVEAALGVLDRALGDEAFPKLTAVRGDRW
FQPVFTSLAADKHPPPFARGAHHVLTGGFGGVGRLFAAHLAKAHGAKLTLLGRSLPPSVA
ELEHSLRELGAQGVLSYGVDITDEVALRRALDDARAQHGPIAGVIHAAGLAGGGFLKGAD
WENYARVIAPKISGTVGLISALENDPLAYAIFCSSIAASDGGAGQAAYAGANAFLDSYAQ
SLRDGGLPATSIQWGRFAEVGMAQRALEELVTRRENGSFFQTTEGAQARGRRHILANLDA
GHWAFYDHRVGGVPLLPGTGQIEFLLRMFGAPKKTPIRLENIRFERPLQIALGRSRQLDV
IHELASNEITLTSRAAGGDDREIVHSRARLVQDAPKPRAALDLHAILGRCPERISSAEDE
LARIPKERIFFGEMWRKNRVTLHKGDGELVVEIVQPKEDEVYAFHPALMDLATGFARALL
ENSAEDAELHLPVAYQEFTWFRPSPSHLFAHCTLRDQDKTEGTVRFDITLCDDSGERCAE
ILGFTLKRIPAGLPAVETRAPDGLSNETAIAALERIWGQSASAVLRVPVLQAATSEKARQ
SRGASASQLTGAEDLAGKLREVVARYLGIDPAAVDDRQSFDEMGASSLVLVQITSALREE
LGVSLGLDAVMAEPTIAGLTRAVATQLGAPDPVADPVAEALVPAESGADGRSAGGVEPAP
SAPRIAMRPAEKTAVAVPRAVTVAGAVDREPLALRLRSGQSHIPPLFCLHPAGGSALAFI
GLMPYLDPSQPVIAIQGRGMVGDEAPDSEVIDMARRYLKIIRTIQPRGPYFLCGLSLGGM
VAFDLARRLQKTGESVAWLGMIDSPGPGQTTKRQVQGDDAHVLDYVRTSAPDMYPTFRRL
AEQNPGFLRTWRLHNLALERYNPDPLDVKIHFFRANERDEVIADHPEHGWIPLARDGIDI
RPIPGNHLTMTAEPHARVLGTLLQQSLRASLTRLSEG
>A0A1Y5PDW8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|uncultured Mycobacterium sp|TrEMBL
MVLTEHPTQQAPRFAIVGYAARFPGAADADQYWDVLHNGRDAVTEVPQDRWDVEEFFDPD
PDAPGKIVTRRAGFVDDVTGFDAPFFGVSAREANVMDPQHRLLLETAWRAVEHSGTAPTA
LANTRTGVFIGLATHDFLGMASDALSYPEIEAYLAVGTSSAAAAGRISYRLGLQGPAVTV
DTACSSSLVAIHQACQALRLGECDLALAGGVNVMLSPATMITFSHSRMLAPDGRCKTFDA
AADGYVRGEGCGVIAVKRLEDAIRDGDHIRAVIRGSAVNQDGASGGLTVPNGVAQQRVIH
EALESAGLAPSDIGYLEAHGTGTSLGDPIEVQAAAAALGKGRDADRPLLIGSAKTNIGHL
EAAAGVAGILKVVLSLEHQELPKHLHFRNPSPHIPWDRIPVRVVDEAVAWERSEKPRIAG
VSSFGFSGTNAHVILEEAPQVAPRAAGAPADDRRFMVLPLSARTPAALVQTAEHYRSWLS
GHPEATLADVCLTAGAGRAHFEHRAALVVNSLESARELLGALTDDLPAPGLVRGDSADAP
KTAWLFPGQGSQYAGMAWELFETEPVFAETMTRCAEAVGEALGKPLLDIIFDADGTETLK
QTRHAQPAIFAVEMGLARLWQSRGFEPDVVLGHSVGQYSAACVAGVFSLEDGARLLTERG
RLFGDLPTGGRMCAIFADADRVERLTDKFPSLSVAAYNGANTVLSGPAADLEQAVAELTD
DGARCDWLDTSHAFHSALLDPALDAFEAYANGFEFGAPQRILVCNRTGAALGRNAKLDGS
YWRRHARQPVQFAKGVATLAELGCALLLEVGPQPVLTAAALRAWPDPATAPKAVPSLRRN
GADHRQVTEALAGAYVAGHLPDFGALVPQPAHKLDLPTYPFQHRQYWFSSKQVQTTASDG
PRTEAVRLLEDGRIEELAALLDVAGTSQTTAEVLNKLAAQHNRQRSAQSIADIRYEIRWE
RSVNSSPAEIGEGAAWLLIGDDAVVMQPLIDALTTNGHRHRVLGLPVSDADEERLVDELR
TAVHDEPELRILHIAALDSDGAPSMRSLLRMQHRVLGGTQRLFRAAAAAELRTPIWVTTH
GAQRVTNDDTVSPEQSSLWGFCRAAALEYPQVWGGLVDLSGRGADEWARLIKQVVTASAG
EDQIALRAETVQVPRLVRRNGQPNSIPLELRADATYLVTGGLGSLGLEIAGYLAAHGARQ
LVLTGRRAPSEVAQRRIDALREQHGCNVRVIAADVADPHDVARLLATVQAELPPLAGIVH
AAGENNTTPLSSLESAEMDRVFSGKVWGAWHLSEASADLQLDFFLSTSSISSVWGSYGQT
VYSAANAFLDGLTWRLREQGVPAISVNFGPWSAGMADQDARTQLERRGIRTLSPSDALAG
MADVMAAAGSQGPAQAVVARIDWARFLPIYLQAGRRALLAEVAREVPESISATPPASGST
RLVEQLTAAPVQQRKKLVLEHLRNTVAEVTRIDASEIREEAGFFDLGMDSLMAVELRRRL
EQAVGKELPATLAMDFPRLSDVADYLLSDVLNLNERAGSQLAAPPTSLATSATDEPIAII
AVACRFPGSPDVEAYWDVLSGGVDAIREIPEDRFDVDEFYDPDQQMPGKIYTRNGGYLDS
VDGFDPEFFGISPREAVWIDPQQRLMLEIAWEGLERAGYAPSAVRGSRTGVFVGVGANEY
SHLLSGESVENLEAHFITGNALNAIAGRVAFTLGLEGPAMAVDTACSSSLVAVHQASQAL
HSGDCDMALAGGVNVLLSPASIVAASRARMLAPDGRCKTFDAAADGYVRGEGCGILVLKR
LSDAQRDGDRVCAVIRSSAVNQDGASSGLTVPNGGAQQRLISAALTRAGLTGGDVDYLEA
HGTGTPLGDPIEVQAAAAVYGAGRDPNRPLLMGTAKTNIGHLESAAGVAGLVKVVLSLQH
DLLPQNLHFQNRSPHIPWDSLPVRVVDRATPWYADGRPRRAGVSAFGFTGTNAHVLIEEA
PQPPLAEDAADEPSDGAAAPEAVREPLSLLPLSARSAQGLVALAQRYSTWLDTHTESSLA
DVCFTAGAGRSHFEHRAAVVATSGQEAKMLLDDLVANRLRPGVLRGECTDPPTTAWFFPG
QGSQYPGMARELFDTEPVFADTVRRCAQAVDPILPRPLLDVLFSSDREAAETLRHTSFAQ
PAIFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSLEDGARLIAERGRLFGSL
PAGGRMVAVFADPEYVEHAAGTFPRVSVGAYNGRNTVLSGPGEDLEQIVAACSADGTRCT
WLETSHAFHSELLDPVLDEFEAFAKQFAYAVPSRPLVCNRTGAVLTNETPINAQYWRRHS
RQPVQFTESVRTVAALGCSVLMEIGPQPILTAAALQIWPETSATPRAIVSLRKGANAQRQ
ITEALATTYICGHRPDFAAKHHAPSHRLELPTYPFQRRRYWPKVSGLASGGADGVRLSGI
LGSAKDLASGDTVYTTVLSVKTQPWLAHHVIYGTVVVPGATYAAMALASAGAPARVKEVF
FYEPIVLPDKASREVQLTLHPVDDGWKFQVHSRPHGVRDSEWSLNSDGTLLAGVDPDEES
PEGTLSPDEAIEQMDRTRPQELFDIFHDMELAWGPTWSTSLKSLWVGQSEAIGDIAIGEE
LSEHLGSEPIHPVLLDLCTGVAFPAFPATLAAEQGMSDLFLPLRYGQVTVHEKMPRRFYC
RARWHENALTNETQVFDLDFVSPDGRMLGGIREFTVKRAPREALLRGLGGDSTRLLYSLG
WQEIAAPVAESAEPETTKTSNGTWLIAGFDALAADVPGAATVADITDVQSWQQAFAKAAE
GGAPVRGIVWRSSGQPHMYETTDDLAQRLEAEIATLLGAAQTALSSQAAQQGTLADGLWI
VTERAVATEPGEPVDPVQAALWGFGRTLIAEQPTLRVRLVDGDASDESLSWLAGALGTTV
AEPEMAVRQGRFLVSRLLHWARNGQLPMPRSDDYALAPTERGAIDNLRLTEVEVAPPKAN
EVQVRIEAAGLNFRDVLNVLGLYPGDPGPIGGDLCGVVTELGSEVAGFEIGQRVFGSMQG
AFASRLNVPAPLLATVPDGIGAVDAATIPAAALTVRLAFDWAKLKPGDKVLIHAASGGVG
LAAVQMARAHGATVFATASKYKRATLREMGVEHVYDSRTTDFADQILADTGGEGVDVVLN
SLTNEGFVEATVRATAKGGRFAEIAKRDIWTAEQMTALRPDIAYEIVALDVTMMTDPDHI
QKLMVEVSDGLAKGEWTPVPAEVYPLTEARTAFRRMQQARHIGKIVVQMPKPLQPRGDRS
YLVTGGLGALGLHTASYLAQLGAGDIVLTSRRAADAEMQQAIDAITERFHCRIHVFSADV
GVESEVAGLLEKIRAELPPLAGVAHLAGVLNDALLPEQDLERFRTALRPKAYGAHQLHRL
TMDDDLEFFIVYSSASAVLGSPSQSNYATANALLDGLVAQRRAQGLPATAVNFGPWGHGG
MANSQAALANLSAQGMMPLEPSAALAALGESIRHGAAQATVLKANWQRTAKMLGGIRPPL
LDQVLPSGDGTVTGDSEMLRQLLELPVTARGGFVTEFLQREVQGFLRLAQPPAATSRFLD
LGTDSLMAVELRNRLFGQFGGKFDISPTAVFDYPTLGELAEHLVSQLPDSDPPSGDTESP
QAPEAAESAAAPEAVAQRDAEPTPED
>A0A3N6F157|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-17|TrEMBL
MALAAPAAHGSDPMDTAFWDAVENQDFGTLADTLGIDADGRDSWSDVLPTLSSWRRQQRE
QSVVDGWRYRVVWKPLERAVAPGDAVPSGTWLIVTSQGVKDDEPVRAVEQELARRGARTV
RVPFEADDTGRAMALQWLGDALVDGPVAGVLSFLAQDERPDPFHPVVPAGVAATTSLVQA
MTDLDVTAPLWCLTRGAVAVSRAEPLARPVQAQTWGLGRVIGLEHPERWGGLIDLPAVLD
EQSAARVCGLLVGAGDEDQLAVRSQGVVVRRLVRAPADRTKAAKPWRPRGTALVTGGMGA
LGGHVARWLAGHGAEHLVLTGRRGADTPGAAALQAELTAMGVRVTLAACDVADRTALAAL
VKEVEAADGAPIRSVVHAAGETLQAGLRESDPAQFARVMAAKAAGAAYLDELFADGSLDA
FVLFSSGAAVWGGAAQGAYAVGNCSLDALAEHRRSRGLPATSVAWGGWAGGGMVDDAAED
TLVRRGLRPMAAESAVRALVQAVEQGETCLTVADIDWTRFASAFTISRARPLIEDVPEAA
AALRTDEPIEDMAASPAAALRERLASASDAERDRTLLELVRTEAAAALGHPSADAVEPQR
AFKELGFDSVMAVDLRNRLTAATGVRLETTVVFDEPSPVALRDRLRRELLPADTGRDAGP
DVAGAETSKDAEARAVLAAVPIARIRAAGLLDQLLRLAGVADGEEAGAGREVPGSGDRVD
ENRVDEINAMDIDDLVRMATGTKDA
>A0A3N6E9Z8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-17|TrEMBL
MEAPVGVAAELSLADTQFWSAVEQEDFDVLADTLDIEGGDDARSALGAMLPALSSWRRRT
RELSTVDDWRYEVAWRPLPDASAARLSGHWLVVVPETHAEDALTAGCLAALTDHGAQVLP
VTVDGGKLRRDLFAGHDLPADLAGVLSLLQLDHAPHPELPDVPRGYAATVALLQALGEAG
VSAPLWCATRGAVSVGPADPIAGPEQAMAWGMGRVAALEHPDRWGGLIDLPAALDERTAA
MLSGALGGAGDEDQLAVRQSGTFVRRLNRARLGAAPGTRRWDPKGTTLITGGTGALGGHV
ARSLAREGAEHLLLVSRRGPDAPGAQALRDELTALGARVTVTACDAGDRDALAEVVAAVP
AEHPLTGVVHTAAALDDGLLDTLTPDQLANSLHAKARAARNLDELTRHHDLSAFVLFSSF
GGIVGTPGQGNYAPGNAYLDALAQERRSAGLVATSIAWGAWGGGGMAEGEFGETLNRHGL
REMAPEAAAGALRQAVEHDATCLLIADIDWERFFVAFTATRPSPLLADVPEVRRIAQDGT
GQAGSGGEEQSALVQRLAGLSEAEQDALLLEAVREQVAAVLGLTGPEAVWVKRAFREVGF
DSVTAVELRNRIGAKTGLKLPVTLAFDHPTPQRLAGFLREQLVRDGETVAVTALEELDRI
EKALAGVAPDDAGRTRVVRRVQALLTRLQGGSADEVPVGEEIESASDDEMFELLGKKFGI
S
>A0A1T6TIH6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus subsp. massiliense|TrEMBL
MTAVHVDPVVISGMAIEAPGGIDTPAAFWNALADGRELISAFPRDRGWPVDELLSLSNLD
GWGRISDAGGFITDASAFDPTFYGITQREAVAMDPQQRVAMRVAWRALENTGLNPGAVDG
SEAGCFIGISPNEYGPPVGEVNAHSGMRVVGRGQLGAAGRISHGLGLIGPSVCVDSACAS
SLAALHIAASAVRADECEWAIAGGVCVMGSPGGFYEFSRMHALDPDGHCRSYSDEANGTL
WGEAVGMVVLERESRARALGHRVYGRIMAVRTNHNGGGKPILVPRGRAQAKLVAATIAAS
GVDPADVGMLEGHGTGTRAGDPLEILALQSTYGAGGSNALLGSAKSNAGHAQSAAGMVGL
IKLLLSGQYGHIPPSLFADNPTTKIDWSMTGIRLATKLHPWEPKDGIRYGAVSSFGAGGA
NAHAIIAMPAMDTQGEDGDDF
>A0A2S9XYI5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Enhygromyxa salina|TrEMBL
MIQSQRDPRAKAPADNYEPVLTWLKDAMSRALGLAPARIDPNTRFREFGLDSEQITALVA
RLASHIGHALSPVAPWEHPTPLALAQHAVAVQNNRAPTTSGANLGGRGPGLGASMSTEAI
AIVGIGCRLPGSVSNPEQLWDLLRNRGNAVKQVPTDRWDVKDYLDVDRAAPGKMTTRWGG
FLDQVDQFDATFFGVSPREAQQMDPQQRLGLELSWEAFEDAGIDPLGLRGSNVGVFVGAM
WCDYARLSSDDPTIIDQHTGTGADTSIISGRISYTLGLEGSSLTVNTASSSSLVAVHLAC
QSLRAGETTMAVAGGINLIITPHGSVVMTKLGTQNPAGQCRAFDAGANGYVRAEGGGLVV
LKPLSRAIADGDRIYCLIRGSAANNDGFSNGLTAPNPKAQESVLRAALANAHVDPATVHY
VETHGPGTILGDPLEASALGAVIGSAHTPDQPLRLGSIKTNMGHLEAAAGIAGLMKTALS
LYHRMLVPNLHFEQPNPHIPFDQLRLQVQTEVEGWPVADQVPRAGVSSFGFGGSNCHTVL
EAAPKSEALLLPLGSVTAAGLRRQVLAALDFAFELSTWNETAALCRALSERTGPGSHRVS
LMLNAPEQLIDGLSGLLAGGLRSLEPAPERPRVVFVCSGHGSQWLGMARTLLLGEPVFRG
ALEAVDREVQSLAGWSVIDELLADSIRSRLDNAEVVQVVLFSVQVSLGALWTSWGIEPDA
IVGHSVGEIAAAYLAGVLSLHDATRVVVERGRIVGELAAGRGAMLQVSLPESMLLERLGE
AAKDLVIGAHNSPRSTVLSGPRQAIEDAEALLAQRGVRIRRVEIDFASHSPEMLPLIAPL
EAALEGITPRPAKIPMISTVLVEPIAGPECTPSYWGRNLRSPVRFRQAIELLAEEGSTTF
VELSSHPTLLGSIEQTLDGAKGSFTALPSCWRNEDERGAMLKSLSRLFALGLDPGWPAVW
AHAPQLEMLRPEIAERMFDTVGVHEVEVWEVESRYRVPLLISAKSEIALQAQAERLQAHL
LEHPDVTLADLSHSLATTRAHFERRASITAHDINSALEALDALARGDANSDPRIVVSEAR
VEGKVAFVYSGQGSEWPNMARTLLQISDRFREQLEACDRALSMYVDWSLLDVLGGVEGAP
PLDRTDVIHPVLFAVSSALTTLWRLRVGLEPDGIVGHGVGELTAAYVAGALSLDDACKII
ALRGRALGRLTGRGTVAVVPLPPAELDPHLKRWGERVTICAHDGPGATLLAGEPDVIDTL
VAEIESARRLPIDYAPATTQIETVRDEILAALEGIAPRAVATTLYSTVRAEKLVGRELDA
EYWYRNVRMRTRFADTIEKMLADGYRFFIEVSPDAMLREALEACLAKADVVGVAVDSLAR
GEGGPMRLMRSLGELHTRGLEIDWHKISVGRRVTLPTYAFQRNRFWVETAPKQRPVADAV
RAQLPAADAGFWSAIESGDLDTLANALNIADDAHRGSLESLLPALTTWRRNHQERTTLNA
WRYRVEWKPAPTPPTLGNLTGTWLIVSASEPEDPEVIEIICQGISGAGGTVVRVPVDEDE
PDREDVTNRLLRAKLDGAAPRGVISLLALVEEPMAEQPMLPGGLALNLVLTQSLGDAGIE
APLWLLTSSAISIGRADTLSHPLQAMAWGFGRVAALEHPDRFGGLVDLPAQLDLKATRRL
LAILSNEAREDQLAIRNTGVFVRRLVRAPLTDLSDHKPWKPRGTILVTGGTGTLGARVTR
WLAAAGAEHLVLTSGHGPDAELMELGTRVSLVACDTTDREAVATLLDQLDAEGEDLTAVI
HADGVAQTTSINETSLDELVRVAGAKVSGARYLHELLKDHDLDAFITFSSIAGVWGSGRQ
AVYAAANAYLDAFIEHRASLDLPAVSVAWSAWASGSSDDASQHELRRRGLEPMDPKLAIQ
ALQQGLDHGDVNMIVADIDWGRFTPSFAAARPRPLLDDIAEAQAALDTSDSSSEPDEARL
LARLRGLSESERLRALVNLVLGETAAVLGYHDASRLDAHTGFVDLGLDSLMAVEVRRRLQ
RDTGLSLPATLAFDHPSPQHVANFLLEGLAPALGMAAELGDDRRAQDDAAPSHEPIAIIG
VGLRMPGEIVDLRSLWEFLSAGREAVGPLPSTRWNVEEFYDPDPESKGHSYVREGSFLDE
IDQFDPAFFGISPREAKNIDPQHRMLLEAGWQALESAGVVPSSLRDSLTGVFVGLGPSDY
DHLRQGPGEAYTFTGTQTSFAAGRLAFTLGLQGPALAVDTACSSSLVAFHLACNALRNHE
CELALAGGVQILAAPDVFVQLSRTRALAPDGRCKTFSANANGYGRGEGVIVFSLERLSDA
RKNGHEVLALVRGTAVNHDGASSGITAPNGTSQQKLLRQCLEDAQLAPADIDYVECHGTG
TSLGDPIEVQALAAVYGEGRPPDRPLLLGAIKTNIGHLEAAAGLAGVAKLVACLQNDATP
ATLHTKPRNPHIDWQSLSVDVVDGHRPWLPREHGPPRRAGVSSFGMSGTNAHAILEAAPA
DDTHVIAPEMPTPPELPLVLSGRTKVDLVAQASALAKHLREIGPELDWQVSALDLGYSLA
TTRTHFQSRLALTIDSDAPADLIIDVLDNFAKSGAEPRDGAMTPRDHRKGKLAFMFTGQG
AQRPGMGRELYNRYPTFRDALDTVCAHLDRHLDRPLFELMFSEPDTAEAALLNQTGYTQP
ALFALEVALYRLWNAWGVTPDILIGHSIGELAAAHVAGVLSIEDACTLVAARGRLMQALP
EGGAMVSLQAGEDEVRPLLDARISIAGINGPMAIVISGEEQAAADISAHFEAMGRNVLRL
SVSHAFHSPRMEPMMDEFRRIASRLDFKPPKIPIVSNVTGERATSDELTSPDYWVRHIRS
AVRYLDGVHTLEAEGVTTFVELGPHAVLSGMTPPCLSDKALRQAVVLPTLHKRKPEVETL
NMAVAGLHVHGYELDWEAFFAPFGPKRMGLPTYAFQRQRYWIDRSETRAADVSSAGLTDA
EHPLLGAAIRLADSDGVLFTSRIALAEHPWLASHVVFDAALLPGTAFLELAQVAALRVGL
DRVDELTIERPLALPSKGGVLIQLSVGSPDEAGSRALTFFTRAETERDAPWRRHASGFIG
QGPRIADFDLHSWPPPGAEPINLGPDARTAYATLDEAGLAYGPDFRGLVRAWTHGNELLV
EVKLPERPARNADRFGLHPALLDAALHPLVLQYLDHDSDAVQLPVSWEGVELYATSTTAL
RVRFTPKQSEGAVSIAIADAAGEPVAFIETLVTRPAAAEHVREALVSQRFDGLYAVEWSI
PLDTGAVDSAGRWAIVGDDGGIELADTLSRASVDVSEYPRLDAIVDELDKRKPAPEVVLV
PWFQADAAADPYTSTHRALALLQTWLGDSRFVDSRLIFLTRRAVSTETREDVRDLAAAPL
WGLVRTAQVENADRSLTIVDLDDEEVSLWALPAALACDEPQLALREGMMLAPRLARPPAL
DQLTPPTGSATWHLAVSTKGTLDNLMLDEWPQAMGPLGPDEVRVAVRAAGLNFRDVLNAL
GMYPGEAGELGIEGAGLVTELGSRVRHLAVGDRVMGMMPAAFGPVTVTDSRVITKIPEHW
SFEEAATVPIVFLTAYYALVGLGKLERGQKVLIHAATGGVGMAATQLARHLGAEVFGTAS
EPKWPTARELGYDEAHLASSRTLGFEQKFLSATGGRGVDLVLDSLAHEYVDASLRLLPEG
GHFLEMGKTDVRDPARVAADYPGVEYQAFDLMVLDPELIQAMFTKLSKLFEDGALKPLPT
TVWDIRKAPDAFRFVSQAKHVGKVVLELPRGFDPDGTVLITGGTGALGTMVAKHLIERHG
ARHLLLVSRRGQDSPNAKHLGVELELLGAQVEFAACDVAERESLARVIDAIPAAHPLTAV
FHTAGVLDDGVLPSLDAERIDKVFRPKVGAGTVLHEVTADRELSAFVLFSSIVGVMGNAG
QASYAAANAYLDALASHRHARGLPATSLAWGPWGGEGMAARLSDADRARMRRRGLVALAP
VDGLALLDTALGRPDPMLVPAHLDTSAVATQSEAPPTMLRGMVRAAPRPRAAIATGATTV
TLEQRLAALPEVDRERAVLDLVRTEIASVLDLGRPESLGPDRPLKDLGLDSLVAVELRNR
LQAVTGMRLPSTLLFDYPTSGALAKMIREELNLDQAVAVAISSPINNEIDRLETMVRAMS
DADLERSGVSARLRKLVAPFMDESELNQGGEAKAEEFAGVSDDELFDMIDSEIKGMS
>A0A2S9YGE1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Enhygromyxa salina|TrEMBL
MDKSELLRQSLSRIHALKARVAELEAPQAEPIAIVGIGLRFPAGLDDPRQFWAGLARGVD
VIREIPEQRWPAGQAEARFAGMLDRIYEFEPGFFGVSEREARTMDPQQRLLLEVAWSALA
DAGLPLASVRGSETGVFIGASGFDWTLLAFGDQAIDAYAATGSSHSILANRLSYLWDLRG
PSLSVDAACASSLVAVHLGVAALRRRECDRVLVGGVQAHLVPHTTMSLARFGMMAADGRC
KAFDSRADGFVRGEGCGVVVLARLSEVDLARDRVYAVIHGSAVNQDGRSNGLTAPNTLAQ
ARVLRAALADAGVEPEEVGFIETHGTGTALGDPIEFQALSSTYGASSRPCYLGAVKTNLG
HTEAAAGVAGLIKAALAIHHKEIPANLHLERLNPDVEIEGTRFRLPREQTAWGPPHHAAV
SSFGFGGTNAHVVLGPPPEPPSPTADAGQAQLIAAISAASREAFFERVEQLVDLVDEPSV
EPGDLTYTLAARSTHLAWRGHAIGHDRPSLASALAKAHPTLAASAPPRVVFLFSGQGGQW
LDMGRALADGSEVFRAALERCAEAIARVAGWSLAAALASTTELARVDRVQPAIFAVQVAL
AALWRSVGVEPDVVLGTSMGEVAAAHVAGLLGLEDAARVITTRSRLVAERLDTPGAMATV
ALSEAALRERLSARPSDLEIAVVNSPSNVVVAGSPAPLLELMAELERDGVFTRRIQVDYA
SHCSHVDMLADAIEDALPGLAAGDGPRTRMLSTVTLDWLEDATRPSYWRANLREPVRLWP
ALSEVLRPAGDVVIELSPHPVLTVPLEEPLAQLEPPVSLCCPMARGGGPEVFLDALGRTW
ARGLEPRWQTLQPGGRVTSLSSYPWTRRAYGPELSLSDPRAAIATPASSAATVTKERGAT
ITEASIEALVIETLTHELGASSDLAMDVPLRELGLDSLMASHLRARLAERGLEVSLLDVL
QAPGIHALVATIRAKLRDRSETAPDASAASSGPWFVCPRPRPQADVVLYCVPFGGGSAGA
FRPWVDEMPEWLELRAVESPGRGTRLGEPWPATADALVTGLTEAILEDLEDLEVSRRRPE
PGDDRPSFALYGHCSGSLIAYEVAKRLSAAGHAPRHLFVAALGPPARYDLDELVATVERS
GAPLHDMSDELLLGFLRSVEFQGLEEFERDPELRDMAMATMRADSRMMMSYRPVDGGPLA
VPITAIGGARDPAINIYELWQWARETRAWFDWRWLPAGNHYFHADHVDELAEIFAVLRAD
ELPLPHPRTTAALAPIDVVRGFYAAHGDEPSAAAPFLAEAVNWRILDPSERELSDPGQPQ
PQPQPQPRSWFADPRLSVRAVAMHELELEAHGDDEIDASSGLTLAPAGSEARPATHRARY
RVRDGRIVSATVHIE
>A0A221W4A3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinoalloteichus hoggarensis|TrEMBL
MTGADDLRYFLKRVTAQLHDTRERLRQAEQASREPIAIVGMSCRFPGGIASPEDLWRVLA
DGRDVLGGFPVDRGWDLDRLHATGTPGSSATHRGGFVDAVADFDAEFFGISPREATAMDP
QQRLLLETSWEAIERAGIDPASLRGGNTGVFVGTNGQDYVSGLRQVPEVAADHLLIGNAA
SVVSGRIAYTLGLEGPAVTVDTACSSSLVALHWAIQALRSGECDLALAGGATVMSTPGAF
VEFSRQGGLAPDGRCKAFAASADGTGWSEGVGLLLVERLSDARRLGHPVWAVVRGSAVNQ
DGASNGLTAPSGPAQQRVIRQALAAAELSTSDVDVVEAHGTGTRLGDPIEAQALLGTYGQ
HRSRPLLLGSVKSNLGHTQAAAGVAGVMKMVLAMHHGIVPETLHVDAPSPHVPWSTGAVE
LATGAVSWPASDRPRRAAVSSFGVSGTNAHVVLEAAPEIADDPAPSAAESPLPEPAGHPI
PWAVSAKSPAALDAQIARLRGLTADPRDVGHSLATTRALFDHRAVLVDGVEVARGVAGDL
DVVLLFSGQGSQVVGMGRELYGCFPVFAAALDEVLGLLGSGVREVMWGGDGEVLGLTGWA
QPAVFAVEVALCRLLEWCGVSPGVVVGHSVGEVAAAYVAGVLSLGDACVLVSERARLMQA
LPGGGVMVAVEASESEVVPLLSAGVSVAAVNGVSSVVLSGVESEVVGVVSRLGGRRWSRL
RVSHAFHSSLMDPMLEGFREAIGGLSFSEPRVRWVGGGDGGSVDFWVRHVRETVRFHDYV
SGLGEGCVFVEVGPGAVLSGLVDGGVPLLRRGRSEVESFVSALARLHVAGVPVDLTRLYS
GGRRVDLPTYPFQRRRHWLDIPETAADVASAGLVAAGHPLLGAAVMLADSDGVVFAGRLS
LRSHPWLADHVVGDAVLLPGTAFVELALRAGEEVGCGRLHELTIQTPLVLRADEAVQVQL
TIDEPDETGLRRVRVHSRAESEAADAPWTRHADGALSPARPAPERAAPSPADATPLPVEE
FYTELAGHGLAYGPTFRGLRAAWRRDDEILAEIALPEDARRDAERFGLHPALLDAALHAS
ALVGAGDDLVRLPFAFSGVTLHASGASTLLIRLSPAGPDATALELFDPTGQPVATVETLR
LRPVALDRVAGPRTDVRDALFRLDWVPVPNDGAPDSVRTVDCTDLAGDVTAAARHGIARA
LSALRSDERLVVVTRGAVAVSPAEVPDPAAAAVWGFVRAAQSEHPGRFVLVDSDVPVDAA
RLAGLGEPQLAVRDDRVLAARLTRAAAGPGGIDWAAARRTLITGGTGMLGAAVARHLVTV
HGVERLVLTSRRGPDAPGAAELRDELAGLGADVTVVACDVSDRAQVAALLTEHPVDAVVH
TAGVLDDGVIQSMTPERVGTVFAPKADAAWHLHELAGDLTAFVLFSSAAGVIGSAGQGNY
AAANAFLDALAQSRRARGLPAQSLAWGLWDEASGITGELGSTDLRRMSRGGVRPLSTADG
LALFDAAAGVDSAVVVPIRLDLSVLADQEAPPLWSALTRTARKPSKRPTAVARHADSAEL
LELVRGRTAAVLGHGSGSDIEPTRAFQELGFDSLTAVELRNELQAATGLTLPSTLIFDYP
SPAALAARLHAERHGEPAAAVPAPPAVAVSDDPIVIVGMACRYPGGVTSPADLWDLVAHG
RDAVGGFPDDRGWDLDALYDPDPEHVGTSYTRHGGFLYDAGLFDAEFFGISPREASAMDP
QQRLLLETAWETIESAGIDARSLRGSRTGVFAGLMYHDYLGRLHRVPEDLEGHLGNGNAG
SVASGRIAYALGLEGPAMTVDTACSSSLVALHLAAQALRAGECDLALAGGVAVMATPGVF
VEFSRQRGLSADGRCKSFAGAADGTGWSEGVGLLLVERLSDARRLGHRVLAVVAGSAVNQ
DGASNGLSAPNGPSQQRVIRQALANAGLSPADVDVVEGHGTGTRLGDPIEAQAVIATYGQ
DRPHPLVLGSVKSNLGHTQAAAGVAGVIKMILAMRHGVVPPTLHVDEPTSQVDWSVGAVE
LATESVVWPDVDRPRRAGVSSFGVSGTNAHVILEDPSVWYRPQPLDGRDTAEVAAGDTPA
SLPPAAGAVPLVLSARSDAALRAQAARLSDFLASQQAPDLRDVGFTLLARSSFARRVLVA
GTHVDQVRAGLAEVAAGRLEPGPRAAGSGVVLVFPGQGSQWVGLAVGLAAVSPVFAARLG
ECAETLSEFVDWSLPDVLSDEAALSRVDVVQPVLFAVMVSLAELWRSVGVVPAAVVGHSQ
GEIAAAVVSGGLSLRDGARVVVSRSRLIAGLGGGGGMVSVGLPASEVSALLPVGVSLAAV
NGPTSAVVSGPEQALAELVADCESRGVRAKWIPVDYASHSVLMDPLRDELLHSLAAVTPR
ASEVPFYSSVTGEVADTASLGAEYWFDNLRETVRFDRAVESLLSDGLGVFVESSAHPVLT
YGIGEVVEEHGAENALVVGTLRRDDGGLDRFLASAGELFAHGVDLDLTPFLTGGRLVDLP
TYAFQHERYWLDAPQLAGDVRSAGLADADHPLLGAAVELPADAGVVFTGRLSPRTHPWLA
DHAVAGTVLLPGTAFVELAARAGDEVGHGVVEELTLQAPLVFTADAVAEVRVSVGAVDDA
GLRPVSVHSRGGDGWTAHATGALSAPAAAPADDVAEWPPPDARPADLDGFYADLAMRGYD
YGPAFQGLRAAWRRGDELFAEVAVSDEERAAAERFGLHPALLDAALHAVGLGAAAAEGIG
LPFSWSGVRVHTAGATSLRVRITTAADGSVSLYGIDEAGAPVVSVRSITVRPMAGHVTTD
SLYRIDWVPIRTTDDRAAAGSVFECPSGTPRTVVGAVLSHLQQRLSAADDRPIVVVTRNG
VGVSPDEAPDPAAAAVWGLVRSAQSEHPDRIVLIDGTPDAELDVERLAALGEPQLAVRGD
VVTAARLARASAEGRGGWDRTGTTLITGGTGTLGAAVARHLVTEHGALRLVLTSRRGVDA
PGAARLRDELAALGAEVAVVACDVADRDQVADLLAAHPVTAVVHAAGVLDDGVVDSLTPR
HLDTVFGPKVDAAWHLHELTENLTAFVLFSSASGLLGAPGQGNYAAANTFLDALAQHRRA
VGLPAQSLAWGLWSETSTLTAGVTRSRGVAAFSVEDGLALFDAALAIDEPVLAPVRLDLR
AADSVPPLFTGLVRTRRRSAERRTDLRERLIGLAPEARERLLLDLVRTEAAVVLGHRSAE
DVVVDRSFLESGFDSLAAVELRNAITRSTGLRLPATVVFDQRTPAGLARHLRQESAAPRP
ANDPADTVSTLFRRAVDTDQRDRGFELLNAVADLRPSFHDAAEPADAPAIVELARGPGPR
VICVPSPMGMGGAQQFVRLAAAFGGARAVSALSVPGFAEGEPLPATIEAAVGLLARSVRE
LPGDEPFVLLGYSAGGLLAQATTRHLQDVGRPAAALVLLDTYLPDSKAMEGFATHMLAGL
FAREESFGPYTADRLSAMGRYVRLFEECVVRDVDAPTLFVRPGSLGDDETGDAQWRASWD
SAETEAEVPGDHFTMLEHHAADTARAVEDWLRAGGV
>A0A117EBP9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MWLFSGQGSQVVGMGAGLYERFPVFAEAFDEVCDLLGGSLRETVFRGPQEVLDRTEWAQV
GLFAVQVGLARLWESVGVKPDVVIGHSVGEIAAAYVAGVFDLADACRVVGARARLMGALP
EGGAMCAIEATRGEVEEAGVSVAAVNSGDSTVISGSVDEVERVAEAWRRKGRRTKRLQVS
HAFHSALMEPMLDDFAEVVRCVAFKESSLALLSNVSGTLATPEIATPEYWVRHVRQPVLF
QPAISEVADRAGVFVEIGPGPVLITAAQHTLTTEPVLTASLAEGRPDDVAFMQAMGRLYT
AGYPVDWSVFFPTDPAPQIVDLPTYPFQRQRFWLADLKEPEVAAQADEVGFWAAVEGGDV
EALCDTLHLKDDVQRSALGTVFPVLAEWRRERSERQVVDGWRYRIDWRRVELSASDAPGA
WVVVAPEGEGWTRVVVQELEAAGGAVTVVGVGSDRAETAALLRSVSGDGPPLAGVLSLLA
LAPGGGASSTLTLLHGLLDSGLDTSLWCVTRGAVSCGGADPVVSPAQAAVWGLGRVAALE
HPQLWGGLVDLPSRAEVLDSGALYGVLCGGGGEDQVALREGGVFGRRLVAESPGDELSDD
WQPAGPVLVTGMVAPLVDHVTRWLDEIGAEPVVEADVPVRTVVHTSLPGALAPLAEVTPQ
ALGEAVAAALTLGERSAETVLFFSSAAATLGGSGHGVYAAANACLDALAQRHEGPRTVSV
GWGVWDLPDATDATDATDAPDVTTPASLSRRQGLPPLSPHLALKALRTALAGPPGHTLVA
DIEWERLTPLFTLARPTRLFDAIPAAVSVLEASPENTETSSALRRDLAALPARDRVGVLL
DLVRTQVAGVLRYEPGRTVRAERAFKDLGFDSLVAVELRNRLRAATGLRLPATLVYDHPT
PRALAEHLLERVMPDGALPPVTRLDEVAAALDGLPPDDPRRRELVRRLRALLRKESDAAE
PAGRSEPDDLSDADADHMFALIDREWGAR
>C6WN16|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064 / NCIMB 13271 / NRRL B-12336 / IMRU 3971 / 101)|TrEMBL
MDHPTAGQHEAPGGPQDAVAVIGMAVRLPSADGPDAFWALLRDGVDAITDVPAGRWEQAS
PGVTRGGFLDSVAEFDADFFGVSPREAAAMDPQQRLVLELAWEAVEDARIVPADLRGSRT
SVFVGSIRDDYAALLYQHGTSAITPHTVTGTHRGIIANRVSYSLDLRGPSVTVDAAQASS
LVAVHLAAEGLRDGAVDLAIAGGVNLNLLGEQTVGLERFGALSPDGRSRPFDAAANGYVR
GEGGAVVLLKRLDRALADGDPVHAVLLGSAVNSDGATEGLTVPGERAQTEVVRAAFAAAG
VAPASAQYVELHGTGTPVGDPIEARALGAAMAGREDDPLRVGSAKSNVGHLEGAAGIVGL
VKTALAIRHRRLPATLNFATPNPEIPLGELGLRVHAELSDWPHPDRPLVAGVSSWGMGGT
NAHVVLTEAPAPVRRPAHPDGGGAAAGTAPAAETAPAAAGEPAAGSGRPRAAEGLPAAGN
PPAAETGLIAGSAPAAEAGRGLAADGLAADGLAADGQAAEAAVVGDPAAAPEHAPAAAPP
PVSAPPTAHVPWLLSGRSRAAVQAQAAALAAHLTDERPVDVALSLATTRTAFEHRAVVVG
SGRAELDAGLAALASGEAAANLVRGEVGATGGVVLVFPGQGSQWAGMAVELADSSPVFAG
HLAACGRALSAFTDWSLDEVLRQVDGAPGLDRVDVVQPALFAVMVSLARLWQHHGLRVDA
VIGHSQGEIAAAHVAGALSLDDAARVVCLRSKAIRALAGTGGMAAVTLPAAEVAERIAEH
GGRVSIAAVNGPANTVVAGDPEALREIVADYQARDVRASVIAVDYASHSADVESLRAELL
ELLEPVRPRHADVPFYSTLTGEVLDTTGMDASYWFRNLRHTVNFHDTVRLLLSDGHRAFV
ETSPHPVLTHAVKSTIEAEGVAGATALGSLRRDDGGPRRFLLALGAAHAHGLALDWTGPL
TDAPQLVDLPTYAFQRKHFWFSGDGVITRAATPASANAPAPQDERTGALRARLTGLSDRE
RLRVLVDLVRANAAPVLGFDGPADVAEGRTFKDLGMDSVTAVEFRDQLGAATGLALPAAL
TFNQPTPRALAEHLDRELGGATAEPAVDGATPTSDDPIAVVGMACRFPGGVRSPEQLWEL
VRDGVDAISEFPDNRGWDTEALHDPDPDKRGSTNARYGGFLHDADEFDAAFFGISPREAT
AMDPQQRLLLEVAWEAFERAGIDPATLRGADAGVFVGAMAQDYGPRLHQGAEGHDGYLLT
GNQLSVASGRLAYTFGLEGPALTIDTACSSSLVAIHLAGQALARGETSLALAGGVTVMST
PGIFVEFSRQRGLSADGRCKAFSADADGTGWSEGAGLLVLERLSDARRNGHPVLAVVRGT
AVNQDGASNGLTAPNGPSQERVIRRALGAAGLRPSDVDVVEAHGTGTSLGDPIEAQALLA
TYGQDRETPLYLGSLKSNIGHTQAAAGVAGVIKSIEAIRNGIVPRTLHADEPTPHVDWEA
GAVRLATDSAPWPDTDRPRRAGVSSFGISGTNAHVIVEQAEPADTPAAPAESDTTTGPLP
WVLSGRGAGSLAAQAERLLGFATSTEHTTADVGWSLATTRTALDHRAVVWGEDRQDLLAA
LAAVARGESGPTAVTGQAAPTRTAFLFTGQGAQRARMGLALAEASPVYAAAFAEVCAALD
PHLDRPLREVVDSGDGLDETGFTQPALFAVEVALFRLLADHGVRPDFLAGHSIGELAAAH
VAGVFSLDDAARLVAARGRLMQRLPRDGVMIAVEATEDEVLAELAGHGDRVGVAGVNGPT
ALVVAGETEAATAVAEALAARGRRTKRLEVSHAFHSPLIEPMLAEFAEVAATVAYAAPRV
PLVSTVTGRLADPAELAAPDYWVGQARAAVRFSDAVGALLDEGVTALVELGPTAVLSALV
PAIAAGAGVDVVAAPLLRADRDEPRSVLSALAALFVAGVDVDWAAPYRGGRARRVDLPTY
AFRPQRFWLDAPTGGDVTGVGLAPAGHPLLGAAVDLAGGRLVLTGRLAATSHPWLADHAI
AGAAVLPGTAYLELALWAGGRVGADHVDELTLAAPLVLAERGGTLVQVVVDAPDADGSRA
LRVHARRDRDGAEWVEHATGTLTPTPPAADTDLGAWPPNATELDLTDAYARLAERGYGYG
PVFRGLERAWRAGDDLFAEVALPADQWPAAASFTLHPALLDAALHPLLPGVADDGDTTVL
PFAWSGVTAHAEGARSLRLRHRVTRPDQDTLVVSVTAVDTSGAPVLTARSLVLRPVSRAA
LRDSGGATLLRPEWRPAQTGGPVPWSAVGAEGFVDVFALPGDATPTRAYYDLPDLAQALG
GDDVPRHAVVLLPEPDGDPARAAHATTRAALELLQVWLADPRLQDTALAVVTTGGGGARP
DESPHHAGVWGLLRSAQSEQPGRFALVDHDGTAESWAALPSALGTGEPQLALRAGEVLVP
RLVAAEPEPATAVAWDAGTVLITGGTGALGALAARHLVREHGVRDLLLLSRRGPDAPGAA
DLVAELTAEGARVTVTAVAAQDRAALADALRGHDVRVALHTAGVVDDGVVTSLDARGLTT
ALTPKVDAAWNLHELLGDRATLVLYSSVAGVLGNPGQGNYAAGNAFLDALARHRAHLGRP
ATSIAWGLWADSSGITGALTDTDRTRLARNGVLPLTGEAGLALLDAATASGLPEVTAAAL
DHAALRALGERLPAVLRGLITPAATRRAAAGEAEPSADGGSALERRLAGLSERERDTAVA
ELVRATVAQVLGHADGSRVEMAAAFKELGFDSLTAVELRNHLHTATGLRLPSTLVFDYPS
PSAVAGYLSAQVSGPAAPDETRQDRVAATEDDPIAIVAMACRFPGGVRSPEQLWELVRDE
VDAVGDFPTDRGWDTDALYDPDPDRAGRTYTRSGGFLHDAYDFDPEFFGMSPREALATDP
QQRLLLEVAWEAFERAGIDPATLRGSSTGVFAGVMYTDYTEQSGQLPAELEGYLASGTAG
SVASGRLAYTFGLEGPALTIDTACSSSLVAIHLAGQALRSGEADLALAGGVTVMSTPNPF
IEFSRQRGLSADGRCKAFSADADGTGWSEGAGLLVLERLSDARRNGHPVLAVVRGTAVNQ
DGASNGLTAPNGPSQERVIRRALGAAGLRPSDVDLVEAHGTGTSLGDPIEAQALLATYGQ
DRETPLYLGSLKSNIGHTQAAAGVAGVIKSVQAIHNGLMPKTLHVTEPSPHVYWDAGAVT
LLTEATPWPDAHRPRRAGVSSFGISGTNAHVIIEQAPEHGQPGEGGADPVVPWLLSAKTP
AALKAQADALAAFLAEHPDTRPADVALTLATRRATHERHAVLVGSDADDLRARLTALDPA
AAGRTTGAGRLAALFTGQGAQRVGMGIDLVHAHPAYEAAFDEVCAALDPHLGRSLREAVT
TGEALDETWLTQPALFAVEVALFRLWQSWGVRFDFLAGHSIGELAAAHVAGVFSLDDAAR
LVAARGRLMQQLPATGVMIAVEATEEEVRAGLAGQPGLVDVAAVNGPRAVVLAGEEQATL
AAAEPWRALGRRTRRLKVSHAFHSPLVEPILDAFAEVAATVTYHRPTIPIVSTLTGAADA
PVDTPDHWVRHVRGAVRFAPATTALVALGATTFLEVGPDTVLATMAEQVLDALPERRDRA
ALASTRRDRPEVDTTAETLALLHTRGVAVDWAAFLDGAGARHVDLPTYGFQRDRYALVVA
PGAGRTAAAPDWEEIHPPRPAGPRSLVVLDLDHGAADLPGLPVVTTAADVPADADAVLLP
LAVHLTADPADTPEARYARTRGTLDLVQGWDGPRLVVTTTGIAPALGGDRAGEDARLAWN
LLRAAAEHNGRVLLVDLDTDRPDPDVLAALLAAGVPLAAARGDRLLVPPREGAPTAEPVT
SRLLADLAAAPPAKHRTILLAAVLAEVASVLHRDDADGIEEDRALQELGFDSLTSVDLRN
RLNAATGAALPATAVFDHPTPAALADHLLGLLAPGGPEPAAPLHAELDRLESLLATAPRG
GDGAESTAEVADRLRAILARLTEPTAAANALGEDPVGQLAEATADDLFAFIDNELGRTAG
>Q3M3U4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Trichormus variabilis (strain ATCC 29413 / PCC 7937)|TrEMBL
MQTQDLTPLQKAIIALKEARTKIESLERTQSEPIAIVGMGCRFPGDANNPEKFWELLHQG
KNGITTVPPQRWDIDAYYDDDPDVPNKMYARHGGFINNVDQFDPQFFGITPREAIALDPQ
QRLLLEVSWEALENAGIAPQKLTGTQTGVFVGIGIDDYAKRQIKHHIPIDAYTGSGNAFC
FAAGRLSYLLGLQGPSLAIDTACSTSLVTIHLACQSLRNGECNLALAGGVSLMLSPEVTL
YLSKTRALSPDGRCKTFDRDANGYVRGEGCGMVVLKRLSSAVADGDHILAVIRGSAVNQD
GASSGLTVPNGTAQQAVIRQALANAKVTPEQISYLEAHGTGTALGDPIEVRAIDNVFGKG
RSPNHPLILGSVKTNIGHLEIAAGMASLLKVILSLQHQEIPPHLHFQELNPDLAASAKSL
KIPTSVIPWQPTEQPRMAGISSFGLSGTNAHIIIEEPPQLTVTQAEVDRPLHVLMLSAKS
EAALHTLAADWENLLRNHPETNFADLAFSANTGRGSFNHRLAIVAQSTAQARQNLAAFNQ
KQPSLNVFSQEVEKGRQPKIAFLFTGQGSQYVGMGRQLYETQPTFRQALDECDRLLQPYL
KESLLSVLYPQTPTANPLVNQTAYTQTALFAIEYALCKLWQSWGIQPQGVLGHSVGEYVA
ACIAGVYSLQEGIELIAQRGQLMQALPQTGTMAAVFAPVETVARAIAPYGNEVTIATINS
PENVVISGVKAAIAAVQADLIAQGIDVRPLQVSHAFHSPMMEPMLGEFKQVAAKINYQTP
RIDWISSVTGAEITHSIDAEYWCQQIRDCVQFAPAIATLAQQGYDLLMEIGPHPVLTRLG
KQTLSDPQILWLSSLHREQDNWQSLLQSVATLSVHGVALDWSGFEQDYVRRRLLVPTYPF
QRQRYWLAETEFIQPEVVPVAAISPETSKIVAATETLESQILSLVAKITGMNPQQLSLDA
TLEGGLGLDSIMMTQLMNGIIKFIPPGQRESFHQVFSLRDLMQISNLGELLKVLEPWQTV
DLQETTAVDVIPSADIPTIDQTSDVVDILHSQLPLLVSYWSLNSNSLFTKVQVAGDFNLE
IAQHSWQKLIDRHPMLRARFHIPQGATSFADYQLQVLKNPSPPAIPLKDIRHLASEEQTQ
AIAQEVHHWLNYRWSLTQWPLHKFSVLQLSDSVYQMFLGNEHLIADGLSNHVIIREFLEI
YRACIDQDTPDLPPALSVADYQAQVQAMNAWQDVDEDRALAAYNNSQRHTAYLWNPQQQI
RQQTPLFDNQKYILSAETTAKLITKTREWRVPMNTLLLGAFIQTVSKLDTTSEKIGIQIP
TSGRVYPGVDASGVISSFAQNLALSFTPPQAQQDWQTFLTEIQQTVQQHIGSGLDRAQTR
QMGVIFRDSFVLENGRIPDHSLSLIQGALKSNLYLPYTGQTHIHHYYGSLSVTEYQAGGM
NASGTIDILQEIFDSRLHLFASYDSNTFDLSVIDSLMKSYLAQIEELATLPIEEQVSSAF
VSPIFINKDIGKNLRQITSEICHWAIEESEMSDDLEADLGLDSLELIRLVTRLESVYGKN
YRQCLLNCRTLEEMVVVLSAESLAISA
>A0A173XVE7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Bifidobacterium pseudocatenulatum|TrEMBL
MKAVYATGTNYDDPLSVLEVGTMPEPETKPFWSTIRVNSASVNHHDVWSLQGVGLSDEQT
PMILGTDAAGVLEEDIPVRKGLKAGSEVVLYTFVGTDGAGVMPGERRSILSERYAGTMSE
YTQVPSANVFAKPANLNLDEAAALGTSWLTAYSLLFASANVKPGDTVLIQGAGGGVSTAA
IQLAHAAGLEVFVTSRSEDKRARVLQLGADAAFETGARLPRKADAVIESVGAATWSHSVK
SVRPGGTIAICGATTGDQPGAELTRIFFQDIRVQGNTMGSREDFARLLKFVEHADLHPVI
DSAYAIDDAHLAFSKIVNGDVFGKIVLHI
>B4CUJ9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Chthoniobacter flavus Ellin428|TrEMBL
MSKDRIAIIGVGCRFPGGINTPDALWKLLVEGREAVSDVPPDRWNVARFFDAEPGIVGKS
IARRGGFIDGIDQFDPQFFGISPREAPYVDPQHRLLLETAWEAIEDAGIVLDFEKGTDIG
VFVGISHNDYHTIQATPSDSAGITPHSPTGTAHSIAANRISYCLNLTGPSVAMDTACSSA
ITALHAACEHIWGGHGDVAMAGGVTVMITPGGFIGFSQASMLSPDGKCKAFDAAANGFVR
GEGAGMILLKKLSQAIADGDPIHGVIVATALNQDGHTNGMMLPSPDAQARLVKDACKIAG
IDPLQIRFVEAHGTGTAVGDPIEAHALAEALCANRPADEPLTIGSVKTNLGHLETAAGVA
GVVKAMLVLKRKQIPANLHFETPNPNIDFEKLRLRVNTTLEPLPEAKGPRLAGVNSFGFG
GANAHVILEEPPQRPHPEHHEKPVERPWPIVLSARSEKALRTYAGTFAKWLEERSHANGD
APLLPDLVYSLGARRNHHAHRLTLATSSMTELIRELEGFATEQESLKIRTAFTPRRETAP
RIAFVMSGQGPQWWGMGRELMRHEPVFRQMMERCAAAMKPYARFSLLEELGRSEETSQMS
RTEIAQPAIFAMQVALAALWKSWGVEPAAIVGHSVGEIAAACVAGIFSVEEGARVIVLRS
RFMDGCARGEGTMLAVGLPEEEVRALIARHDRTVTIAAINGPRSLTLAGPRLSLEAMLAE
LEPQGVFARLVKVDHPFHHPLMRPASEELEQAIADLKPQTETTPFFSTVTGGRCSGEECQ
ALHWGQGVRQPVLFAPAVNAIAEFGVDVWLELGAHPALVHSLQECLAARGGTKPPVLSSV
RREREHESLLETVLDLHRVAVPLNFAGMTPSRRLLAMPAYAWDKSRWWNESNDWRDGRLA
AGGRGLLDARLAHSTPTWTARLDNRHMAFLKDHKVDSHVIFPAAGFVDMVLEAGVQLFEG
RPFVVEDFEIRKPLILPDPASGVYLELTYEPNDRTFAIQSRFEQSSSWSLHVVGSIRGER
TESPFASTTYDGHAAKGVEPVEVEGFYRYMSDLGLRYGEEFRPIRELAAGAGHSSGRVTL
SEASATRASEFPLHPVLFDGALQTFSAGAATIEDRRSRMKLPVRFARILFLRSPGASTRV
QANVLQCNTEFVEGRIGLYDEAGQPCVLVDGFRAISVTGVRRSGAPGGTRDVIYHVDWQR
TASSSRASLPPVALQQLHGVAEHALEEVVSTRGRKELEAAMYAGDDLAVALLAQGLSQMG
VTAGAAISAQSLRVAATMHLAFERLMLGLVKHGLFEKTATGWTATPKFTKAAESAQKTLR
GYIAQHSGHLPEALLCVGNCHDLGPILRGEKDAVQVLFAGAGAELLDQFYGDGLYTSQWL
TAIAAAVREAARQLPEGRGLRILEVGGGTAGLASHVLPLLERGLHTYTFTDVSPGFFPGA
LGKLAAFPEVECKVFDLEKSGTEQGFEAGSFDFIIGTNVLHAVSDVRATLGYLRELLVPG
GSLGFMDTATPQLWTEAVFGLTSGWWRFTDRDLRPEQPLMERRQWENVLLEVGFSETASL
PGLVGPTGGEGQFCMFARQAWEPATTEAAVALEAPAEKSWLIFADEGGLGEQLAAQLRTV
GARCRIAHKAHEFATTGIDTFTLRAEEPEDWSRLLKACADPQPERIVYLWNLDATEVSSE
DPLMGTDALLHLAQALEAIYPAAKLRIDSITRGAQPVGREASATAVAQAPAVGLLRVILN
EYTNLACRGIDLPPVAAPTDLQALWSELLRTEPEREVALRGEARYAQRLDRGRPVVQKTL
EASVPLRLESRERGHLDTLRFRSFPAAGSRPGRSAHRRQSRGHELPRRPQGACALPRRSA
GRAHLRRRNRWPGESRRCGRETRRTGRPRPRSRRLRSGHADAGPRGRYPPHSVRAVL
>K2FC30|6-deoxyerythronolide-B synthase|EC 2.3.1.94|uncultured bacterium|TrEMBL
MKNLYYKNDVCVVGIGCVLPDANNVHEFWNNVLNGHCSIESIPDDRWKKDLYFSSDKNEK
DKSYSHVGAFVKNNQLETIIKKHKLQSIGSNRLHAMTFEATTQALECLNSTFLLGSSKNT
SVFLGCMEIDEALTKEKFFSYNKESLQDYVEKNNPKSKDQILDKIENHFISSSLSKDDSL
IASTLTTSVIDLIKQKFNLQGEGALVDAACASSLAA
>A0A100J4Y2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MDVKRQPVVPPTATADTRTTVPEPIAVVGMACRLPGAPDPASWWALLCEGRDAVTDTPPE
QRRTDSALEGPGGYLDRIDTFDAAFFHIAPAEATATDPQQRLLLELGWEALEDAGIRPPT
LARSRTGVFVSALWDDYSRVPGQPLTRHTMTGVHRSALANRLSYTYDLTGPSLTVDTAQS
SSLVAVHLACESLRHGDCTLALAGGASLICSPHTTRLADARFGGLSAHGRCRTFDADADG
FVRGEGGGLVVLKTLTAALRDGDPIYCLIRGSAVNSDGATDGLTRPSEQAQRDVVRLACA
NAGIRPHEVQYVELHGTGTPVGDPIEAAALGAALGQDEARTEPLAVGSAKTNVGHLEAAA
GIVGLLKTALSIHHRELAPSLHFTAAALPLADLGLTVRTEHGSWPCPERAPIAGVSSFGM
GGTNAHLILDAAPPPPAVGPNSWTGPVTWTVSAHTAPALQAQAARLRGHLTEPDAVRVSR
ALSTTRTALAHRAVLLGQDTGELLDALDVLAKGGQSASVVRGEVDPEGERAFLFSGQGAQ
RPGMGRELYAAFPVFADALDTACAALDAHLDRPLRDIVLGDDREPLDRTGYTQPALFAVE
TSLYRLAESFGLTAHCLLGHSVGEIAAAHVAGVLSLDDASALVAARGRLMQGVTATGAMA
AWQASAQEAREMLAGHEERVAVAAVNGPTAVVISGDRETVEALTAGWRERGRKVSRLKVS
HAFHSPHMDAVLDELRAVAAGLTFREPVVPIVSGVTGELIGDGLADPEYWARHAREPVQF
LAGVRGMCARGVTTFLELGPDAQLTAMARECFPEGVRRRPVVVPVGRRGRDEVSTFIAAL
AQAYVRGGEVDFAQGCGAEGRGAEGRGGQGRGAQGRGARVELPTYAFQRERYWPGAVPQE
PPQDAVPPQGAVPPKAPVLERPDALALVREHVAAVLGATPAAVHPTHTFKQLGFDSAAAA
ELGERLRTATGLGLTATLTFDHPTPDAVAGHLTGLLTGTPPDPAPTPVPVAPDDDPIAVV
AMSCRYPGGADSPEALWRLLADGTDAIGDFPTDRGWNLEHLFHPDPDRPGTSHTRHGGFL
YDAAGFDAEFFGISPREALAVDPQQRLLLECAWEAFERAGLDPRSLKGSSTGVFIGMTGQ
DYGPRLHEPAPATDGYLLTGSTPSVASGRLAFTFGLEGPALTVDTACSSSLVTLHLAAQA
LRRGECRLALAGGATVLATPGMFTEFSRQRGLAPDGRCKPFAAAADGTGWAEGVGLVLLE
RLSEARRSGHRVLAVVRGSAVNQDGASNGLTAPNGPAQQRVIRAALTDARLTAADIDAVE
AHGTGTTLGDPIEAQALIATYGQDRTEPLWLGSLKSNIGHTQAAAGIAGVIKTVMALRHE
HLPATLHVDEPSRHVDWSAGAVRLLTEAVPWTRGARVRRAGVSSFGISGTNAHVVLEEAP
PSAETPPAEELEVAPWAVSARSAPALAEQVRRLGELTDASPTEVGRALATTRTVFEHRAV
LLGHETVSAVAADIGPGPVLVFPGQGSQWAGMGARLLDTSPVFAARVAACETALSPYVDW
SLTGVLRGDGQELTRVDVVQPVLWAVMVSLAAVWAEYGVRPAAVVGHSQGEIAAACVAGA
LTLEDGAKVVALRSRALRKLAGSGAMASLGVGRAEAAELVGPYEGVGVAAVNGPSSTVIS
GPPAEVAAVVADTEARGLRGRLIDVDYASHSPQVDAIADELAGVLAGVAPSSAPVAFYSA
VTGTRIDTASLDAGYWVTNLRRPVRFADAVSALLGAGHRVFIEASSHPVLVPALAESFEE
ADTDAVAVPTLRRHDDGPYRVAQSLAHAFVAGCDVRWEKWFPAGAGLPMVELPTYPFQRC
RYWLDAPSGVTDTSGHAVLGTAVELADGDGWLLTGRISRDGQPWLAQHTLLGNTVVPASA
VVEWALRAADEAGYAGVDDLTFTVPLVLPDSGGLQVQIVAGKGELRVHARPDGTAAWTCH
AEGQLASEAGAETAIGDEAWPPPGAEPVELSGFYERDDVRYGPVFRGLRSLWRRGGELYA
EAVLPEEARGTDGYGIHPALLDAALHPATLGTDPPGAGAVWLPFTFDGVRLRATGASTVR
VRLTPLGGEKTWRVVVSDPAGEEVLTCESLVLVAAEAGQLRAGPALYALRWTPVETALDA
GETVPPVVQEAVGLSDAVADDEPQLALRDGTVLIPRLTPVPAPTEPPRLDPDGTLLLAGP
DTDLLTAIGDHFTRTGQVARTLLLPENGIPPLDDLQLTAVVYASGTHPDAGTVATLDTAT
AHLPLALFAVLRPDRDGYGIPRSAADAACEAVALRRGLALTYDTPDHVPELLDTARAYGG
SLLVATHGTPPAYLRTSTRPQPPARRTAATDKPPTDWSTRLAPLSAAEQLRALVDAVRTH
AAAVLGRDDPETLRGDATFKQLGLDSMTAVELRNRLAADTGLRLPTALVYRHPTPTAVAT
HLRNRLTGAPPPRAADTVLADLTRLENSLADNGHHDTHEITARLEALLTRRRSANSTESA
HRLKAASADQLLDFIDNELGVRHETPTPKAG
>A0A1B9EY17|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. PTY087I2|TrEMBL
MTLLDVLLDAVREAPGQTVVHVRGDGSELTVTLRELLDDSLRVAGGFREAGVEPGTCVPL
LADRSEDFQPMFWGAVAAGLVPVPLAPDTRRILPVWEHLGRPPLVVDASTAPLVDELPDA
ARALSLDALREGPLLREPAPGGRDDVAFLQFSSGSTGAPKGVEVTHRAVLANLEQIRAAS
ALSADDVVVSWMPYFHDMGLIGTHLAPLAARARQVKIGPLSFAKQPRLWFEVAARHRATV
LSAANFALALAVRRVSDDVLARLDLSAVRLLLVGAEPIAPAVWRSFADRTRPARLDPAAA
QPVYGLAEATLAVTFPPPGEVAEPLVLDRASLSGGVAVDAEPGEGSVELMDVGRPVADCA
VRIVDDKGDVLGDRRVGHIMVRGPQLARGYHGLPGVSAETFTEGWLRTGDLGFLRDGRLC
VTGRHKDVLFLNGRTFHATDMEEVAAATPGLPPGAPAVVGSTDPVTGAERVVVFVPWARP
PRDASEVLERVAARVREALLHDDVRVLALPPGAFPRTTSGKLQRRRLRERFEAGGFGAAS
AGEPLAGQPSAGDGALSAEPRADVPRARAQTVEAVREVWARVLGRPVVSIGSHEPFGSLG
GTSLKAMEVLVELEDAFGVTLPPAVIRDHGTVAALAGHLLTVAPGTSSSATEAGKAGEDE
KTGKVRKSGEDGRAGESGAAVAAVIGMACRFPGADTPEAFWDLLIDGHDAVTPVPYGRWH
DDARDRRAAPRKRWAALLEDPAAFDADYFGIGEDEARAIDPQARLFLELAHEALERAGYA
GPRRRGRRVGVFAAVGDSGYREVLDRASADGSPVPTALTGNLPSLIAARVSQGLDLDGPA
LAVDTACSSGLVALHLARRSLLDGECDIAVVGGVNLHLTSTPHRLLEEAQALSPTGRSRA
FSADADGFVPGEGGAAIVLTRLNAARLSGDQVLAVVRGTAVNNDGRSMSLMAPNPLRQRE
VITRAYEAAGVDPASVTYVEAHGTGTAVGDPIELRSLAHAFPERPDGEPRLLGSVKTNIG
HLLNAAALPALVKVVLALGHRRLPPSLHHTPPAPGLAPAGFSVVSEARDWTSAGPLVAGI
NAFGFGGTNAHAVLEQAPESLLADPASSSADAACEVDVEGPHLLTLSARSAGALRDAVGR
LATHLESRPQLSEGDVCRTASTSWDEGPHRLAVVAEGDLRERLAAVVAGAGGGGKGVETG
GVAANVVRSRPRVVFLFPGQGAQSPGQDRALYRTASVFRDTFDEASALLGPVCGRPLLDW
GLDPEVDPAAQAATEVAQPLLVASGVALARQLRAWGVAPEAVAGHSVGEITAACVSGVLT
LREAVRFAAERGRLMGAFTDPGAMLAVRGGEEAVAAAVADSGGSLAVAAYNGPGLQVLSG
TVSAVERAALALDAQGVPTRRLRVSRAFHSPLMRPVADRLADAARALTPRAPSVPLMSTV
TGEWQPVLDPAYLRDHAERPVLFGAAVERLAREGYDTFVEVGPGAPLSGAVRAATEAYAP
GESGDGITVLCALPGRSTGRTDAVPLPDDRNGGRGDLLETVGRLWSLGMPLDRTALDAGH
RRVPLPTYPFQRRRYWADPSSPRPLLHRVVWEDNSLPGKAAEAAGSLRSVLLTGPDPASV
DRLASQLAAAGVRRHEAGDDGRPDAVVLVAGPAPDQDTGDALGRAHDAVLAAFGHALAEF
DETRADRFLVVTEDVHATGTVRERPRPAHAVLGGLLLALPQETPRAAATALDLCSLDTPS
QRLAAVLAELESGGTPGSATVVAWRGGRRLTRRFVPPAADVSAPAGTTRSPLPPDGTFLI
TGGGGGIGAALARDLAGRGRPTLVLTGRSPGLPTGLADELRTLGATVHYRVADVSVERDV
DALLAELPRLDALFHAAGVVRPGTLRNRRPEETADALAAKTRGTLLLSLALRRHGLDPAV
RVAFSSVSAVLPGLAGALGDYAGANAFLDAFAASERHAGRPWQSVNLAALAGTGMAAALG
TGTGAGSTTVRNAGGRPVALAPALAALRTACGVDAAQLVLAELTPTSPPVAPKTPEASTT
TTEAAATGSGPAASGDTDTSTAPLLRRLLASALRLPAAEVLDDEPFLALGLDSLAAVDLV
RQLERELGRALPATLFFEYRTVAELAAHLDSTPALASPALPRAPEPVPDGSPFPLTPVQL
ALHTSSRLHPDVPAHGYVRQTVRGPLDTRLLGRALDALADRHTMLRIRIKDSAGGIASAS
PVQYVAPPSALSTWYEVHELAGRIEELEAALCNRPFDLSTESPLRAVLARESPELSHLVL
VIHHAAGDGYSLNVLAGELWSLYTAFALGDAPTLPALGTDFARYAAAAADERSTTDGAMA
LAADRRYWADRLASRGEPLRLPYDGDPCALPSAPLTTRQSSLDPALTAALEKRAADHGVS
LFHLLLAAHVRCLARWSGQREIAVNVARARRDDRIAGLDRLVGPLADTLPLLCSTDPDEP
VGVLAGRLAGIWLESEQHAGLTGLDLARLLPMDPAGSGPRTVGPAGFSFSRFPAALDERC
PVSVRPTAAGTATAATRLSLLCWQDETVLRFSWNFPVRLFAPETVARLDRDFHDELAATA
AAPLPASGSATLVRRLVERFRATPDAVAVDTGAATLTYGELDRASQALAASLLAHGVTPG
SLVGLLTEPGADTVVAVVAALRAGAGWVPLDAGHPPARLVDQLTRSGARAVLCHAATRAV
GETLGDVTLVPVDVPASPLPRESVPHGNETPGPLADADGIAYVIFTSGSTGRPKAVPITH
RSMENYLDWAIDTFGYDEHDRLAQTASPCFDASVRQLLAPLLVGATVVTVDWDLLRDPDR
LLTHVERRRITVWSSVPTLWEQLLSASEARVRTGAPLPDLSALRWVHVGGEALSPAHVRR
WFDLFGAGRRIANLYGPTEATINTSCHIIRERPDDEVRRLPIGRPVSGTEVEVVGPDREP
LPPGEAGELLIAGVGLTPGYLGEPALTEAAFTVRRGRRWYRSGDRVRCSEDGTLEFLGRL
DDQVKIRGNRVEPGEIEAVLQTHPDVTHAVVLAEDGRLTAFVTPGPGASGSLGAFGSSEA
SGSSGAAAVELRRHLAQSLPSYMIPSRITRVGTMPLTGTGKIDRRALAALGDAPPRSPSR
PAATRTAPRTPTEIRLAAVWSALLQADDVCREDDFFVLGGDSLLVLEVFARLEKQGGPLP
RPTVIYRNRTLAALASAVDAATAEADDTVVDTAADASVDTGVPAPFPLTPTQRGFLLAEA
IAPGTTSSWLTRFRLHGRLDTARFQSAVDTLVGRHPMLRTVFPARVRPAVQQELPSSLRL
PVDFETLTGPGQVEERVTAERARRFEPWAWPLVRLRVLTLAPDEHVLVAHAHHIIGDGYS
AALLVRELITVYDALSRGDVPARVPLRSTFRDHAVRLAQRAEATITDSGAASRDDRWARL
SAPYRPPVLSAAGTGPGTVANRLFHTYGFTVDADQVEALRGLATRNGSTLYAPVLTAYYR
ALAAITGRADLVLGLAVSGRDDALPDVHRVFGPFATAVPLRPASPVSGRRDSRDGRDGTG
FADDLRRLAVEAAEARTYEGAVPALPNGLPLASQFFFTYLDFSAVGPEDGEALTVTREDG
DSVYTPPPAGTDVFLAAGPEGGRLRVTVRAAATAFTPEALAAFADAVRDGLAHAAASAVP
GISTGTGPDRNEPVDAALIGYLPSPADLARLAGLPEAALPREELRTLLFPDGRPQLLETL
RTPLGRSGFVCVPLFADELAPGDALLGHITRGVELASSLGARAVSLAGMIPSLTGYGFDV
LRAVGATGAAPAVTGAPSVPAAPTITTGHAATVVSVVRTVHAALDATRQQLGSLTVAFVG
LGSIGSSSLELLLTLAKEPPARLLLCDVPGSGPRLKELADSLLARGLAEVIEVVESDGGL
PDAVYGARLIVAAVSGGGTLLDIDALAPGTTVVDDSFPHCFDTTRAFGRMERAKDVLVVG
GGLLSAGPAERQVAEGLPAAAVAGYLAQPMVADTIASCRLESLLHSSGAAVPLVHGPVDA
ATGLAYWEAAEAAGIHAAPLHLLTRTIGPGTIDGVVSGRD
>S0G7E3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Desulfotignum phosphitoxidans DSM 13687|TrEMBL
MVRQAVNTTLTPDMENQLMTRPDPVRSALFQISRPIFVTKKNNGPHMSHDLPGPRSGKAE
TSQALPFDAFAPAIPLSALGDPTFTARHHLKYPYVAGAMANGIASVEMVQAMAKNGMIGF
FGAGGLSLSKIEQAVITLTSRLKDAPFGFNLIHSPTDSDLETATVQLYLNHGIRRISAAA
FMRMTPALVYYRIKGLHKDKNGQVKAPNQVVAKVSRIEVARQFFAPPPRKLVHLLLEKKW
ITQEEADLSRCIPMAQDLTAEADSGGHTDNRPALALLPTMLALKQQCMDEYHYTDPLCVG
LAGGIATPESAAAAFAMGAAYILTGSINQSCVEADISDDVKTLLCQAEQADMAMAPAADM
FEIGARVQVLKRGTLFAMRAEKLYQLYRTHARFEDIPEKQRREIETQLLKTDFERAWQST
RAFFESRHLPAQIQKAQTDPKHKMALVFRSYLGQSSRWAIQGILERKMDYQIWCGPAMGA
FNQWAKNSFLAGPEHRKTADLALNLLLGASVTLRAMMLKTQGVVLPPSATAVHPMKKTDI
LALAGSLPQTDSMAADPM
>A0A3S4UD76|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Arachnia propionica|TrEMBL
MTTPDVVSAVVAERPGPLTDVLRLHTATPVDDPLGEGEVPVRMLASTVNPSDAVTVSGAY
GSRTVFPFVPGFEGVGVIERIGPGVPRAATGRRVLPLGTAGNWQEIKRTDHSWCIAVPDD
LDDETACFAYINPLTALCMVQRYCTRVTKHVLITAATSTIAGHLAELLGFHGIRPVGLIR
GTPGHTVANPERWDDVVSTKEPGWVERLRVATGGRGADLVLDCVGGPDGAELFGLLTPGG
LFVHYGLLSGKPLPPECFTGQDGKRVEMFRLRETIHNSPRTELPKLFTPVHAHLRAGRLR
TPIARCVPLTGLVQSLRDNPAAAQGKVLITYRS
>A0A136M5T6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Omnitrophica bacterium OLB16|TrEMBL
MKLGECDLAVVGGVNLILSPQGTIYFTKMRAMAPDGRCKVFDASADGYVRGEGCAVVVLK
RLSEALQDSDSIRAVIRGSALTHDGRSSGLTVPNGQSQQSVIRQALDAAGVHPAEISFIE
AHGTGTALGDPIELQALAGVFGNDRDSYQSLMVGSVKSNIGHLEAAAGIVGLAKVILSLE
QEEIPPHLHFKNPTPHVDWNHMPIEIPVARRPWKQGDRKRIAGISSFGFSGTNVHVIVEE
APQAQSRKSGRGGYSHRTPRLILPLSARSESALRLACSSMHQFLTSRPQASRIWLRDACY
SAATRRTHHDYRVVLQGNSRDELLEQLSWFARGKEPAGNLFSGRKPIHSQPKAGFHFVDP
VPGWSTCSRSLLDEIPAFREAVEECEHICREIADHSILHEMDTPSIVARIDCSASSPCAY
TAFQIGLARVLQFWGITPQAITGQGSGLVAAACLAGCLDLSNAFRILLAGQTGISEPSIS
LSPAQIPLFIPGEGWISPGNMPEGLLAAIQASDVKAGLEGDSSVSAMDALIEIGPLACPE
DNPSQSSPIRIPVPRGEITSWETDSLYRLVALLFSRGFEIRWQGLFPDGGRYVKLPAYPW
QHERFWIERSAQVPSASEGSKNRTEDSWKNWLYRPVWVEAPLEGPHTPTEKKQTWLLFAD
QGGIVRSIGKQLEERGDTTIFVFRDQPVERKPADFHVLDRIDKKSIEALLQSIHPQPIDK
ILYGWPLDAGPGKQESPTQTVEDSVSLCSTFATVLQGLVGNLGASNSELWVVTRDTQPLP
GREASTNQATAPLAGFCTSAAGEHPALWGGMIDIDSNDDPLFAAHAVLDEMTSGSTEDRV
AFSEGRRHVQRLLPFDASQLPPPPVLRGDATYLVTGGYGDLGIEAARHLVENGARRLVLL
GRTALPPRNRWNQEEPTSPAGKAIRAIRQLEHLGAAIHPARVDLSSPKEFADFLDAFHEE
GWPPVRGIIHAAGQAVPGSILDFNPVDFQAMLSSKAEAVPVICRCFKPEDLDFICFFSSA
SSILESPFLGGYAAANAFLDCAAHKLHRLGYSALAFNWGFWDEIGMAAQFRKKSGRDHLS
KGTRGIPTAEGFQIFDRFRSADVPQVMVLPIDWGSWREAHPTTANKPLFREIWRSLEFQT
LKTPSLTGERKSLELLARLTGLADPEKESILLEAVLGQTASVLDLDAGRIAPDDPLDQLG
IDSLMAVELRNWLEVQLGVVIPMTDLLKGPTVRSITLGLLKEISRIPHTIEPARSHSQEQ
PGHLNTFSSEDILGRMDHLSEDEVDRLLHNLLSEDKGGR
>A0A377VZN2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Klebsiella pneumoniae|TrEMBL
MHAPHKRFISNVSGTWITEEQATSPDYWVQQVRNAVLFSEGAAQLLVQPTLFIECGPGNT
LSTFIQGHNQYSDQPTLLTLRKANAAIDDEHMLHRTLAALWVRGENIDWRRFNQTALGKH
IPLPDYPFEQTYYYRYGAALSGYRQYPNPLRRPQDEWLQRVLWRMHDTSLREAFYAPGEL
IIIISADGDKLQQTLMSSGVDSITMPLPISSEDDVWDNDRILMHFHDICALLAHKTYRQL
HCLYAPGAEAGSSLTQSLSGLYRVARWCMHSTTPLASLTVLTHGAFRVQEEDNPEPTLAA
LSGAVNVFAQELHPTEVRLIDIDAQSSDENLNLLTQRLAPKQETVMALRQGMLYLRRFIP
TRLLAHLPPQTGCIPGNVLWIIGGEKGIGRMIGEALAQREGVRVVLSSRTGYHHEAVQQD
ALDVIHCDVTQAEAVRACLATLLERYGRLDGVIFAADATTTLTLHQLSESALRDTLTVKE
RGTANVLHALAQRNLLDERLLLLFCNSLAAVNAEIGQTGYATASAYLDALAQQLRNPLQG
ECAQYRVGCIA
>A0A2G8XS11|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii COUG|TrEMBL
MMSSSVTLKKRKIVLALIFQISLLITQHSFRPSLSCLLILPSKFTSGSTGNPKGVIVTHG
SLLHNCHLCWSAYQFPSHYENDGDDENITNHDFALVNQREFWRRRQEISIKSRGHRLRAF
SWLPVYHDMGLIGFVCSPILCGATLYQMSPIDFIRRPWLWLQGMSKYDCICCAAPNFAFE
VVTRKMPDNVYEHLDLSRVCGFLSGAEPIRASTIDRFCEKFGPKGVRRCAVCPAYGLAES
TLIVTARKTFQTVPKLLIVDSFQLQHEKTVVALTPEATVTMDSEEYQVLVGCGVPLEGVQ
VRIVDPETKKELPPGKVGEIVVYSSSVARGYFGRPDTTKETFCYSFTDLQGKQTPPLGMR
TGDGGFMYEGELFVAARLKDLIIIRGRNFYPQDIEEAVDKVAMVRPGSSAAFAIEVDGHE
ALAVAAEVRLEEGIKGLWLRVKRQFDRSHYEQIVRDISKSVAANTGLTIHRIWLLRPRTI
PKTSSGKVRRSLTKEKLVSGKLEGILLDHAHHQHQAFYHDGPGSSRSRTRTGSGATPSGG
AATRDGTASSNPSGDAHPKNSNTSNSITDSSHSVQRGSLRGDACVAGGRLGPSASHGGVH
HEKDHKHRGDGSGMSSPDQVPGAGAAASESSAHAALTEKVKQTVFEAAKTVLGSSEIPEI
DAPLHELGVDSIGAVEFSELISAELQVDVEPTLLFNYPTLSDVIDFFVRELEGKGSEDLA
VSLEKTGARETTTAIIGAACNLPGGTTSLNAFWDLLMCGVDAIAEVPRSRWDVEEYFDPD
PGADGKAYVREGGFIEDAEMFDAAFFRISPSEAKSMDPQQRLLLEVAYESLYDSGYTREG
LQRASVGVFVGCCSNDWYQVCSQLELGISSYTTTSYAPSIIANRLSYTFGLLGPSMTIDT
ACSSSLVALHIAAQELQGGSCMSAVVAGVNLMLSPHITVAFCKSRMLAPDARCKTFDASA
NGYVRGEGLGSIVMKRLSQAEKDDDRILCILRGTAVNHGGRSASLTAPSGPSQQRVIRTA
LRQAELTPGDIYFVETHGTGTSLGDPIEVGALKSVFGASRDAKTKPLILGAAKTNIGHLE
GAAGIAGVLKAMLALRYKHIPPNLHFKQMNPHIDVREFNVVVPTAPMAFPREDGGRLFAG
VSSFGFGGANGHVILQEALQQPSGDKPPCKRHSKRSIICFMFTGEGYEVSCMGRHLYETD
DVFKEIITKCNDILKRWLNVSLLSILYPPADKKMEMDKMMCQARFGHTALFAFEYALAES
MVSKGVKPDVVFGVGLGELVAAAFSGVMSLEEALYVVTQRAKLIDNLPPFEGVMVACRVS
EQEVEMALSEMEINSRQSISIAAVYGRKNLILSGEQSEIDNVLMKLNIAGRWKYLPVHNV
LTMNLVSDIIPPFTHLMSTVKLCRPKVRLVSSTTGEFVDKEALSGRFWSRQVSQTVQLQQ
AVGNIVASGCSLFVEIGPQVVLTKLAQQSLNGNAKDVTWVPAYDTTSDDVRVFENAVMTC
NEAIKIIGKERSLEEGQHGQEELIFHRKPFPWTEIPHPFLSGHKFTEKDDVVFENAFPRR
AIPLIADHAVNGTAMMPGAGMLEMVGAAALALDLRTTSGAVSLENISFERPMLIGAHRVT
YEYNRRHSLGEGGGAGTSPRTVRTPRLVNHAYTRLGFREKSAEKAISETAGPASTEGGRT
PVAGHHHGSYTKAGVLEDIKDYAHNVLRRAAQHAEEIDVHTPVPPSMAPPSIVARHPREG
SYGSMSRTSGIMGSNDRGDGLTVPLSVEMAIRCRVTKMKEVELSTVWDDEVTDHCFATIV
IADKKQETYSSLQEVRCRCTERMDVNEYYDMLYDAGLQYGPRFRTIQELYRGEKEALARV
HFVGNVKQDPFESGFLIHPAVLDGALQAAGCLLEQSHSGNKVMVPVSVGSATLTKVEVFQ
PCWAHVRLEETKSKAATLNVTIYDEVTREVVASLQNAVLRQVDPSASVVATIPKELLWKV
NWQLVVDGDKEVVGRTPKVLFIGGNIELSEALENAMGSTCKTLSVDALPREKAELQKVLD
AEQWQAIVYVEAVTAGVYDALDVMNAAVRLVQAHYLNLNSGKAVGALWFVTRDTVFRDNG
ADKPGVEIPAHAGLWGLAKAARLEMEVSAGSPISMGCLDVSGADVSSMAQQILHALKSKV
LTMRETEVAVREDGLTGSYFESGVATPGVRFPPAA
>A0A2G8XWN3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii COUG|TrEMBL
MTEAATPQNVTSPADLSKQNVSFRPGVNAVEFVSGYSHAGSVVCSLPSPIFFNKASSSNG
NCESNASTASSSAALGTEASSNVRTGTVLIFDCGSGNTWQHLRQWLSDEGASHIVVVHAC
AEEGADTLGVKTLHPSRVNGGQGCSQTLIKEVKCRPHHPEEVVELFKLLKEGLHFPLVRG
IFYILGEKLDSLLANQTTSSVHDMMKTASGAWSIHHALGQLGMEADLDFFIFFSSISALF
GSISQSISAAVHASLDALAYYRRHLGLAATSIQWAPWADGSSATSPQIVRHWLEKGGVSS
VRNPLAAVSAILKNHTAIGAVVACFHADPTIMHEMGETDQECTFLSSGPAANTRDSTSGN
VKVRTNPVKSRVFQNVSPSTDTCGENHKDELLVILTQLVRREVIEIASCYVFFEGNNLST
DESLVDLGLDSLSAVELRHTLQQRFCVNIEPTFLQANATIDSISALLVTHVATSLTGALP
VLPLSCPGLASAVDDCALVSLALRLPGRCDSLDAFWASLQSDSGYCRPGASEACDQCFMH
RAGSGELPAESQSIGTNLDARKGFCWLSNRDAFDSHFFGISFTEALATDPCHRLLLEATY
EALCKLNTEQQSGTSGTPIAVFATSSSTQMRASLPSYTKPASSQNTQDNNGCLAASFLSY
HLNLTGLAVPIDGSDSASLIALDLGREHLRGTDSVCQAVVVAAGSLLPICSHGWPSACTS
PTIRRFRGRDDYAFPDRETYAVPRGEGIVSVVLQRLSVARENGNSPMAILKGISLIRMGR
GERPIPSQWRTADVKLRRKTIVEALKMSRVEPRTVAVLETDGLTGSQAEDAYTVEAMADI
FGPRHLAESCSPLVIGNASLHIGQAREASGLATLAKLVLMLERGYAPPIPRLRRLHPDVK
RGILPSGFVMFPCKKMDLLAFRQHPDHVYGPNEKRDQKEGRPLIGCVSSLGSDKTSGCFI
VESSPRRHGRTSDTRVSLERAVPLAGTKDACSHNYLHVRSTDGSEGEIRGDDRAVWLFCD
DLWGLQSVGRGLYCSDPAFAALLEQAERVLGNRIPQPLSCLLYPSTTAEFQKAEDALAFP
RIAAFVLFSLQWALATCLRHQEGEPTAVMGLGVGEIAAAAVAGILSLEDAVELLELLSSE
TRTCDNRNKPMPGGNVNSGGLFDRGNSGTGGCGVAQDCKSPWVLCGLNKTPTSESAALEF
SVLESRRGSSSRKSSETPTSNTTPHNRDVFQERFSRKPRRATCPSPIIRHAWEKVAHGNP
ENDEEAELECPSSQSRRANCPSPAIQHACEETAHGNHANDGEADLLMDLFRFRPEPSEPL
GQVTARIALRNATCLFISTVSGRLATDTLIRAAEYWDPLVPKTQRVHRAVETAVQVAKTA
KLVCIGCSAQDGVHLSVGLPSVHPISPSPLRIFCFTGSSPSPQLLAPCESASGSSPRVAV
VEHHGADSNLGGGAPWWKHLLFRLPQLEGFPSGCSASTRLLADRLVADVPTPDNHMINNP
QTAAVQGAGETLGTLREGSSGEGEDGEKGYRSESVNTQHPVYKVYRRCSEPELHESEPSL
LCSDTVCQPSLEKTVELFIGTGLEQQGKLSTVSSSWLVFSDIVAPSPISLYSTLAFQNED
GEQRFCTLNVASQVATVYAEKVKTQVCSIIIECKRGFKPPREIARCHFVKNQTAVGKHEP
AVSSLSRIRWLPATKLPEGWLRTRRPHVWPCKIKVTKAACPLPTRRVDLQEIYWGKRHIL
CRFRMPRNPPRDGVEKSTQLIAILARLVTVSVGVAATCVLHETETSGRYSHSHPGPQVED
DQKTHMDALWVCPYVPFSECWCVIRHRRNGSSIKEGKGRDWETCDVEIFSENGTAVAVVL
GFGIQSHALSMRMMGGRGNDGDSSVSTTVCVA
>A0A378YB71|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia otitidiscaviarum|TrEMBL
MAAWQLAGLELAVAALDDSGLGYAARGSNAAVVFGAAECGPRGTDNLANRLSRALGLRGP
SLILDSEPSSAAAAVDTAARLLADPAVPFVIAGGMGLPLALDISRTHDETQRNGGEFTVV
VVQRVADATLGGIRMHAEIAGIAGFSDGAGEARIPLDPNSAHAHNDRLARSDRGDEPPVL
IALSGRDALEVHETALYWAEQLGTHRSLREFAAATGRLLPGPVRAAILGRDTDDAAAQLR
SLAHRIAATRQPVSAAERARQAERIGQAERVRQAARTEQAAHGQQERGGQVGYPLRTGQP
GPGERTGFPGSAGQPRQSAPPQPAGHHRPARQPAHVPHPRPDECIQAFRHAPQGECRTGP
GCRTEATPATVIEVFGPTTVGAGGGLLLLCSGAREPYPGMGRGMAARYPVFARALMTATD
AVVAAGGPRVWTPRFGFGNGTGGGEFAQAATFVYQVAMAELLARWGVRPDAVVGYGTGEM
AAAAVGGALSLADAARVVVAHSRMAARADYAATAVLEATAVEAMRLVEPMRAAVAVAAID
SPRSVTVSGEARYIDALVRRAHRRTISAQRLTDHNGVWHPAVPSPRSRELAPQLVDELAG
ITPRVPTVALYSTTRAGAALSAEMDADYWGEHARGPVNLTAALEQAAAAGMSTILEIAPH
PTLTPTVREHAAFRDSTHPVAARADEPAAFLRALAHLHLEGRPLDWTALGPFTAPPPPRH
WRHPHPTPHPPTTHDTGPHAVSTTSDDRRGSCTAAPRTPATTPDGEPFADTRTQPTTTPG
NRLRPNPSAPGDERRVVGSGAGAAGEGSSYHPVRWGDCDRPGVVDGPVCDAEVRSESTYV
VTGGLGAAGVRAVCWLLAAGASDVVLLTREPRALPPPLDGWEDRIVLVRCDIADRDDLAQ
VLHDLRECGPPIRGVVHTGAGRTGAAANVLELTAADAPDFTVLVAVADGARGELDRLAAA
HGYRRVVRVDWEDADHRVSDDHA
>A0A1X2E7S5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacter terrae|TrEMBL
MLSTHPTVLPDGRIPVLISAHARDLVQAEAGALARYLHTQRPGVAAVAQTLRATRPIRRY
RAVIRARDTGELISGLDAVYHDVDHPLVARSHHQEAARTAFVFPGQGNQWPGMGADLLGI
AAYRAEADRCEEAFRRAGHASPSAYLCGTDDPDPVVVQAAQFTHAAALAATWRHFGVLPD
ITVGHSLGELAAAYTAGVVDLDAAVAVVIARAELTDDTPGRFGMAMIALGPEAAAEFIAG
TPGWVELSVVNGPESVVVSGEWAAVQRILERADRRGVFARELAVRYPAHTSVLEPLRDRM
FALLPDAQFHSAPVEFIGSVYGGPVPPGRTFRQYWFDNLRQQVRFDLATAAAVARGVTTF
IEMSAHPTLLVPLGDIADAAQLLASTDRDHPADEALAANIAAAAIADPGYRWRDFAAPDA
GAPLRHFPHAPMHTTRLWAGAERSPRPAGEPVVMTEQWAPIDEPTDRPGGVAVIDYTGES
SELAARLVAGLDAGAVEPADAELLVLIAPPADDVEISVAASTFAGHAAGQTSPAPGPTCR
RVWLITRGAERLDGDPPPRPGAAALAALHRSTGFGYPDQTFAHLDLPARPTTADLRAAIA
ALALTDTEVAVRAGRLSVRRLVESPAAPGVPAIPETIVISGGTGAIGMAFAAFCAERGAR
DIILLSRSGAAGATAARLDALRARTGAQISAIRCDITDDAALAALVDEHHPAPAGLMVHT
ASAEAIATEQISGGAVRDALGAKVIGLDNLVRRWPRHADARVLVCSSVLALWGGSGHGLY
AAANRMADTLVTQLRTSGLNANSIRWGLWQSVAVVSGEEKNRIARTGLTPMPPEAAITAG
LLAAPNDPAILAADFDRLAVFFDSQGVVSPFAESLSGSPVQPGADRQAGDVVAAELATVL
GLDHPDDIDMHRALVDLGLDSLLALDLRKRLGRATGRRVAIGPLLAGMTGAQLTATLRDD
TAPAAATERTVFTHD
>G8SJL2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)|TrEMBL
MPSSEEKLVEALRASLKEADRLRGQNRKLTAASQEPIAIVGMACRYPGGVVSPEGLWDLV
ADGVDGVSEFPTGRGWGTDIFDPVPGAAGKSYVREGGFLHDADLFDPGFFGISPNEALVM
DPQQRLLLEVSWEVFERAGIDPVSLRGSDTGVFVGMMYHDYAANSSTGAVASGRLSYVLG
LEGPSMTVDTACSSSLVSLHLAAQALRAGECSLAVVGGVAVMATPEVFVEFSRQRGLSPD
GRCKSFAAGADGTAWGEGAGVLLVERLSDAKRLGHRILAVVRGSAVNQDGASNGLTAPNG
PSQRRVIRKALASARLSSADVDVVEAHGTGTVLGDPIEAQALLETYGQDRERPLLLGSIK
SNIGHTQAAAGVASVIKMVMAMRHGVAPRTLHLDEPSPHVDWTAGNIQLLTEAEEWVVDG
RPRRAGISSFGISGTNAHVIIEQAEEPPAASGTDDESPIVVPLSARTPEALADLADRLSR
AAADLRPVDVGFTVATGRSVFEQRAAVVAGTGAELTAALSTVTASTARAGDLGVVFTGQG
SQRLGMGRELHARFPVFAAAFDEVLAGFTADVRKIVWGDDAEALNRTGSAQPALFAFEVA
LFRLFESWGIRPTVLGGHSIGELAAAYVAGVWSLEDACRLVEARGRLMQALPAGGAMVAV
PVSADQLVLTPGVGIAALNGPASTVISGVESEVLAIAEQFPNARRLKVSHAFHSPLMEPM
LAEFAEIAGGVTYHQSSLPILTSGDVTDPAFWVAHVRDAVRFTDTVAALVERGVGTVLEI
GPDATLTTLIGYNTDELATIAGQHRDAGETTAVATAAGRLFETGTAIDWTAFYAGRDARR
VDLPTYPFQRRSFWLEVTEYLAESWLAQEFGGLRSTGLVASGHPMVGAVVTAPDGPRVVL
SGRLSLAAQPWLADHAVGGTVLVPGTGLLELALTAGRQVDLPVVDELTLMAPLLIPPADG
VVVQVVVDDPDAAGRRAVAVYSRVEDAADDQPWTLHAQGTVSDELGGDRWDALQWPPAGA
EPVDLTGGYPALAEAGYGYGPAFQGLRAAWRRGDDIFAEVATDEADADRYTLHPALLDAA
LHAVLLTRDGDGDGRIVLPFAWSEVSVHAGTGPSSIRVRISPAGTGDDLTIRVADQAGRA
ILTVAALTSRPVDPAAMRATDMDGLLHLAWDRIEAGTAAPGDHEVVMAAAFDPGTGTPVP
ERVRAVLAGVLAKLQEGTSLAVVTRNAVAVADGDPVDVVQAPVWGLVRSAQAENPGRFVL
VDTDGGDVAGALAGGAAEVAIRGNELFAPRLVRASVADSPVFTGRVLVTGGTGGLGAVVA
RHLITGYAVRDLVLVSRRGVDAPGAAELRADLELLGAAVNVVACDVSDRDAVAALLGEFP
VDGIVHTAGVLDDGVLGSMTPERLDRVLAPKADAAWYLHELAGELSAFVVFSSAAGVFGN
PGQANYAAANNFLDGLAQLRRALGLPAVSMAWGLWGSTGGGMGGELSPADVARMRRGGVV
PLTGDKGLALFDAAAAAPVVIPMGLDLTGADPLLVPPLLQGLLRRRPSRTAVSAGASVWR
SRLADLDEPGRLALMSDLVRAQAASVLGFASADAVDAGRAFSDLGFDSLSAVEFRNALAA
VVGIKLSPTLIFDYPTPAVLAEFLLAELTGAGEDVITSTVVADDDPIVIVGMACRYPGGV
VSPEGLWNLVADGVDGVTEFPTGRGWGSDVFDPNPGTPGKSYVREGGFLHDADLFDPGFF
GISPNEALIMDPQQRLLLEVSWEVFERAGIDPVSLRGSDTGVFVGMMYHDYAANSSTGAV
ASGRLSYVLGLEGPSMTVDTACSSSLVSLHLAAQALRAGECSLAVVGGVAVMATPEVFVE
FSRQGGLSRDGRCKSFAAGADGTAWGEGAGVLLVERLSDAKRLGHQILAVVRGSAVNQDG
ASNGLTAPNGPSQRRVIRRALASAGLSTADVDVVEAHGTGTVLGDPIEAQALLETYGQDR
ERPLLLGSIKSNIGHTQAAAGVAGVIKMVMAMRHGVAPRTLHLDEPSPHVDWTAGNIQLL
TEAQEWVVDGRPRRAGISSFGISGTNAHVIIEHVDEPSVTPGADDDGPVVVPLSARTPEA
LADLADRLGEVAASLRPVDLGFSVATSRTVFEQRAAVVATSREGLRAGLQAVTASVPRSG
SLGVVFTGQGSQRLGMGRELHARFPVFAAAFDEVLAGFTVDIRQVVWGGDAATLSQTGFA
QPALFAFEVALFRLFESWGIRPTVLGGHSIGELAAAYVAGVWSLEDACRLVEARGRLMQA
LPAGGAMVALPVSADQLVLTPGVGIAALNGPTSTVISGVESEVLAIAEQFPNARRLKVSH
AFHSPLMEPMLAEFAEIAGGVTYHQSSLPILTSGDVTDPAFWVAHVRDAVRFTDTVTRMI
DHGVGTVLEIGPDATLTTLIGYNTDELATIPAQQRDTGELLATATAAGRLFETGTAIDWT
AFYAGRDTHRADLPTYPFQRRSFWLEVTDYLAESWLAEEIGGLRSTGMTASGHPMIGAVL
SAADSTRVVLTGRLSLNSLPWLADHAVGGTVLVPGTGLLELALTAGRHVDCPVVDELTLM
APLLIPPADGVVVQVVVDDPDAAGRRAVSIYSQDGDRPWVRHAQGTLSADAGAERWDVLQ
WPPAGAEPVDLTGGYPALADLGYGYGPVFQGLRAAWRQGDEIFAEVAFDEVDADRYTLHP
ALLDASLHAVLLTHDGSAGDGRIVLPFAWSTVSAFGDPGTGPKAIRVRISPVGDSGDITV
RVADQTGRAVLTVSALTSRPVDPAAMRAADSAHLLEVAWQPVEAGTAAAEDVVVLEAAAF
DPGPGIPVPVRVRAVLDAVLARLQEGAALAVVTRHAVAVADGDVVDVVQSPVWGLVRAAQ
AENPGRIVLIDSDGGDVSGALGAGEPEVAVRGGVLSVPRLVRSSGGGGGVSFTGRVLVTG
GTGGLGAVIARHLVENLDVRELLLVSRRGRDAPGAGDLKADLEGLGATVNVVACDVSDRD
EVAALLAAFPVDGVVHAAGVADNGVIGSMTPERFDRVLAPKADAAWHLHELAGDLTAFVM
FSSAGGMVLAAGQAPYAAANNFLDGLAHLRHARGLPAVSMAFGLWAVDAGLSAFLQEADF
ERLRRQGLPPLTEQEGLAAFDAALTAGAALVVPLKVDPAVPARGDDTPALLRSLMKPASS
RARRAGGSQVLLRQLAGLGAADRAAALLDLVRNQVAAVLGHSSPAVVEPDRAFQELGFDS
LSAVELRNVLNEVTGLRLPATLVFDYPSATAVAGYLDTQLTGAGADAAPPVTTTRRADDE
PIAIVAMACRYPGDVTTPEELWRLVHDGIDTVSDFPDNRGWDTARIYDPEPGKFGRTYSK
EGAFLHDAAMFDPAFFGISPNEAIAMDPQQRLLLELAWEAAERAGIDPVTLRGSSTGVFA
GLMYHDYGQGSDRASSSGGSLVSGRIAYTLGLEGPAVTVDTACSSSLVALHWAVQALRSG
ECSLALAGGVTVMSTPAMFVDFSRQRGLSPAGRCKSFAAGADGTGWGEGAGLLLVERLSD
ARRLGHPVLAVVKATALNQDGASNGFSAPNGPSQQRLIRQALSVAGLGTADVDVVEGHGT
GTVLGDPIEAQALLETYGRDRPDDRPLLLGSIKSNIGHTQAAAGVAGVIKMVMAMRHGVV
PRTLHVDQPSPHVDWTTGNIRLATETRDWPAVDRPRRAAVSSFGISGTNAHVIVEHAEDP
APRREPVTVQGSALVWPLSARTPEALTALAGRLVRLLEADPGLRAVDVGYSLGGRPVFEH
RAAITGGYRSELLSRARKVTPVAARPGAVGVVFTGQGSQRPGMGRELYAAFPVFAAAFDE
VLAGFTVDIRQVVWGGDAATLSQTGFAQPALFAFEVALFRLFESWGIRPTVLGGHSVGEL
AAAYVAGVWSLDDACRLVEARGRLMQALPAGGAMVAVPVSADQLVLTPGVGIAALNGPTS
TVISGVEAEVLAIAEQFPNARRLKVSHAFHSPLMEPMLAEFAEIAGGVTYNNPRFPILTS
GDVTDPAFWVAHVRDAVRFTDTVAGLVERGVGTVLEIGPDSTLSTLIGLNTAALTTVPGQ
QRDADEADAAVAAVARLFETGTRVDWTAFYAGRGALRTELPTYPFQRDEYWPGEQLLLTP
DATSIGVDTMEHPLLGAAVPLADSDSFLLTGRIARQSQRWLTDHQVFDSVLLPGTGFVEI
AVQAGEQAGCDLVEELTLIAPLVMPDSGAVLQARVSAPDETGRRTVTVHSRAQDAAPDSR
WTLHAEGVLGHGDGALPDDVAVWPPAGATPIDLDGGYDLLADRGYGYGPAFQGLRAAWQL
GDDLYAEVELPEPVRAEAAFYGLHPALLDATMHVLNFAGGEGAPEGQAMIPFSWSGVTLH
ATGSTAVRVALIRQDPASLTMRISDPAGAPVATVAGLNLRPVAVEQLRPGGRADALYRLD
WVGRKAAGGTLPAYADIRLEPTVGDVPAAVRRNTALVLDRVQAFLADESRAGTVLAVVTR
HAFAVADGDPVDIAHTPVWGLVRSAQAENPGRIVLVDSDGGDVSAALASGEPEIAVRGGE
LSVPRLVRSSGGGGGVSFTGRVLVTGGTGGLGAVIARHLVEKHEISDLVLVSRRGLDAPE
ALPLRADLQRLGATVNVVACDVSERDEVAALLAAFPVDGVVHAAGVADNGVIGSMTPERF
DRVLAPKADAAWHLHELAGDLTAFVMFSSAGGMVLAAGQAPYAAANNFLDGLAHLRHARG
LPAVSMAFGLWAVDTGLSAYLQDSDLERLRRQGLPPLTEQEALAAFDAGLTEGHPLVAPL
RVDQAALRSRVGDLPPLLRGLVPVTRRRAATGAADAAKLRARFAGLDATAQEAELRDLVL
GFAATLLGHADPAALDPERDFLEAGFDSLTAMDLRNHLNAATGLDLPPMVIFDNKSPARL
AAWLRAELAVDTTAAETGGDTLSALFRSGLEAGAVGEAYDLLRSVVRLRPRFRTVDEVGD
LAPAVTLRESDSELPRLICLSTPMATGGMHQHSRVVAHLGSPRHVVAIPTPGFVAGERLP
ASVDVAVQALAEQVLRAADGHPFLLLGYSSGGSLAYAVAGYLEERGIEPAGVVMLDSFRV
EDEAAGATMPIRELTLRLYDQESLFGRFDSARLSAMACWFDLVPQLPVRPVRAQTLFVRC
TQSFLELEEGQRDWEAEPLGPGQTLVPLAANHFSIIAERSDATAEVIDRWLTAHAL
>I8U069|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pelosinus fermentans JBW45|TrEMBL
MRKSLIFMFSGQGSQYYHMGKELYSQNTIFRKWMSKLNDIVFQKVGFSIIDEIYNGSKNK
ADKFDRLLYTHPAIFMVEYSLARVLIESGLEPDYVLGASLGEFTSAAVAGVISVEETLEI
ILKQAQLIESHCQVGSMIAVVDSPTLYNQSSIISLHSNLAAINYSSHFIISGEGAKLLKI
EEHLKTKDVIFQTLPVRYGFHSSNIAPIESEYAAFLSKLSFRKPEMPVISCLLSGCATDF
SDKYFWDIIRQPIYFQKTIINLEEQGQFKYIDLGPSGTLANFVRKNLSRDSFSQSYDVLN
PFGQDIKKLEKIKGSFY
>A0A8D3WD11|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces pratensis (strain ATCC 33331 / IAF-45CD)|TrEMBL
MAESEKPDTRMVEALRASLKEIERLRERNRAQTAAAREPIAIVGMACRYPGGVRSPEDLW
RLVAEGRDGIGAFPDDRGWDPDLHDPEPGTPGRSSTGEGGFLYDAGDFDAAFFGVSPHEA
LVMDPQQRLLLEGSWEALEHAGIDPSSLRGSSTGVFAGVMYHDYFGSFGSGSVVSGRVAY
TLGLEGPALTVDTACSSSLVTLHLAAQALRQGECTLALAGGVTVMASPGTYVEFSRQGAL
SPDGRCRSFSDDANGTGFSEGLGVLVLERLSDARRLGHRVWAVVRGSAVNQDGASNGLTA
PNGPSQQRVLGQALVSAGVSAADVDVVEAHGTGTELGDPIEAQALLAVYGQGRSEDRPLW
LGSVKSNIGHTQAAAGVAGVMKMVLALGEGVLPRSLYAGVPSRKVEWGAGRVRLLDVERE
WVRGERVRRAGVSSFGISGTNAHVILEEAPDDDTSPRPEPEPHAPAVMLPLSARSAHALP
AQAERLRDFLDVRPGLPLSAVARGLGTRRAAFAHRAVVVGGDREQIRAGLDALATGSPSA
TAVTGRARTGGRTAFLFTGQGAQRPGMGLELRAHYPVFAETFDAIDAHLGLDLVGVLSGE
DTEAVHRTQYAQTALFAYEVALFRLLESWGVRPDVLSGHSVGEIAAAHVAGVLDLADACT
LVAARGRLMQALPEGGAMVAVRAAEDEVRPLLDERVGLAAVNGPSAVVLSGEREAVLSAA
AGFAKTKRLSVSHAFHSPLMDAMLDAFHAVVEQLTFHEPRVDVVSALTGLPATGQQLRDP
RYWVRHVRGTVRFSDAVAALAGSGVTRYVEVGPDAVLTGLVRECVGEDAAAFVALGRRHG
AETAALLSGLARLHVDGAPLDWAAVFPGTARAELPTYAFRHERYWLDADVPLTMDRPAAQ
PADGPAVPVAPAAVPQAQGLRERLATAPEAEQEALLAGLVRAQTAAILGHAGPEAVEPDD
AFLEIGMDSVSAAELRAALADALGVTVAAGVVFDHRTPAALAAHLRGHLAGGGTGPADDD
IESVSGLVRRAAGDGNWERALTLLHSAADILPAFSSAAEFGEVRDPVRLATGDEGPRLLC
LPSPMALGGAHQYARFARHFHGRRDVLVPDVPGFAPGEPLPRSAEAVVEVVVEGIRRACA
DGRPYVLLGYSSGGQFAHAAAEAMEKAGRPASGVVLLDTYLLADDGTEQLRREMFNGMLD
RESSVGGFGTARLAAMSRYSELIAHCLPGPLTAPVLFVRPEDPFAPGIDGWQAVWEGAHE
LAEVPGTHFTVMEDKAESTAGAVEKWLSDIAPA
>A0A0N1GFV6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MASNEEKLRDYLKLVTADLRQTRKRLQDLEEQQQEPVAIVAMGCRFPAGADTPEALWRLL
ASGTDAVTPFPADRGWDLDALYDPDPDRPGTSYVREGGFLREAPLFDAEFFEISPREAQA
MDPQQRLLLETSWETVERAGILPAALRGSATGVFVGAIPQDYLPRSHDSQADLGGHLLTG
STTSVASGRIAYSFGFEGPAVTVDTACSSSLVALHLAVRSLRSRECDLALGGGVTVMSGP
EMFVDFGRQRALATDGRCKAFGATANGFGPAEGVGMLLLERLSDARRNGHPVLAVIRGSA
VNQDGASNGLTAPNGPAQERVIRTALANAGLTAADVDAIEAHGTGTPLGDPIEAEALLAT
YGQDRQADRPLWLGSVKSNIGHTQAAAGVAGIIKMVLAMRHGVLPRTLHADAPSPHIDWT
GTDLRLLTAEEPWPRQDDRPRRAAVSSFGISGTNAHLIVEEAPAPPEPTADEGARSATPD
AAVRSTTATGGGAAGETGKTGETAVERPLPWVISARSRAALTAQAQRLLTHLDHLDDELD
AGTGLLTAPARIGRALVTTRSTFEHRAVVTGRTLQDLRTGLTALATGEPHPNTVTGTAGP
GGRTAFLFAGQGSQRLGMGRELYEAYPVFAAAFDAVDAEVPFGLREIVFGDDEERLNRTE
FAQPALFALEVALFRLLESWGIRPDVLMGHSVGELAAAHVAGVWSLADACQLVVARGRLM
QALPSGGAMVAVQAAEDEVLPLLNDGVGIAALNGPRSVVISGAADAVEEIAASFRAQDRK
TTTLRVSHAFHSPLMDPMLADFRAVAETLIYNTPRIAVISNVTGGPADPAELTSPDYWVR
HVRQAVRFADGVRALAERRVGRLVELGPDGQLTALAQGCLDGGAQVYATVLRKDRPEPES
QLAALAQLYVSGVAVDWETAFPEDVEAADDLDPDRVRVNLPTYAFQRRRFWSRDTGAGFG
DLGAVGLGSAGHPLLGAAVELAGGDELLLTGRLSLATQEWLRDHVVAGAAVFPGTGFLEL
ALRAGERTGCDRVADLTIAAPLMVPERGGVRVQVRVDAADDDGRRTLEIHTRTEDTLDTD
PWTLHVTGTLTAAGEQADPDGAFDFGAWPPPGAVAESVEGLYERFGTLGLSYGPVFQGLR
AVWRRGDEVFAEVGLGEEQEAVAGRFGLHPALTDAALHAVMFTPALGDGRARLPFSWNGV
TLRASGARGLRVRMVPTGSDAVALELADPAGGPVASVESLVLREATGALTAADRRREGLF
QVDWTKLPVPARSSDPTMIGNSLPGPDEPVPADVFVRVERPAGDSAEAAHTVTTRALELV
RDWLAEERFEGARLVVVTEGAVAVDEPSVDPASAAVWGVVRAARAESPGRFALLDVDGTE
ESWAVVGSALASGEAEFAVRGGAVFAPRLGRVGSGGELAVPAGELPWRLDVVEKGTLEGL
ALTAAPGVEGELVAGQVRIAVRAAGVNFRDVLNALGMYPGDAKDFGLEGAGVVTGVGAGV
TELAVGDRVFGMFSGAFGPVAVADARRVARVPEGWSFAEAAAVPIVFLTAYYALTDLGGV
RAGESVLVHAAAGGVGMAATQLARHLGAEVFGTASAGKWGTLRELGLDGAHMASSRDTEF
EAAFLAATGGRGMDVVLDSLAGEFVDASLRLLPRGGRFLEMGKTDVRDPEVVAAGYPGVA
YRAFDLMDVAPERIGEMLADLVGLFEAGAL
>A0A0N1N956|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
HDTLVRDPGLAPADGLGTTALGRRHLRHRLVVTAPAAELADALGAFVAGRTAPFHTREVD
PRQLPTPAFLFSGQGTGHHPATTAALAARFPVVAEVLRECAEAYQQETGGASPFRQETDD
VSPFLDRLLHGSDPAHGDTAFAQPALFALQVAQARLWRELGVVPATVAGHSVGEYAALCT
AGAFTVTDGVRLLCRRGRLMQRTAPGAMLAVFAPEPLIGQLLADVDGLELAVRNGPEHHV
VAGPPEAVANAQARLAEQGVRGEPLPVDRAFHTALLDPMLDELGAATADIQLLPIETEFI
SGLDGTAHRPGWRPTPDYLLQQARRTADFHAVLRTLTPAHVLLELGPGATLTGLVRHALP
DTPCVPTTAPGKGVDHLGTLWTAVARLHCAGVDLNWTALLDGCAGRRIPLPTYPFQRRSH
WVGPPPVPGDGPSSTIHTDREAHVTEHAVLERVLDLTAQHLGHDRSALRATETYLGLGAD
SLQLIGMLRQLEGEFGVRIAVRELLEDAGSPELTARLIAKRAEQPRTPTTTAPKAAAAPT
PPLPTIEDAREDTTPYATRAEVAELRRQIDLLAETQAALITQLSTAVALLNAERSR
>A0A0N1GER3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
DLVELFEAGALRPLPVTCWDVRRAPEAFRYLSQARHVGKVVLTVPAPLDPDGTVLVTGGT
GGLGALVARHLVTEHGLRHLLLASRRGLDAPGARELVAELAELGATADVAAVDVADRDQL
AAALHTVPAGHPLTAVVHTAGVLDDGVVAMLTPERMARVMRPKVDAVANLHELTRDADLS
TFVVFSSVMGTFGGAGQANYAAANAYLDAFAVARRTAGLPATALAWGPWAPGAGMTAELT
DADLRRMERAGMRPLTPERGLELLDAVLDLGAGGERAAVLPVDLDLVGLRRRQADEVPAL
LRTLVRVQGRRKAEVGGGDHQQDLKARLLAAVPADRDRLLADLIRGAAAAVLGHGSGTDI
ELAHTFKELGFDSLTSVELRNRVNAATGLRVPATLIFDHPTPAALVRHIKSELLGAEEPL
APALLSTPTPTSVDDDPIVIVGMACRFPGGVGSPEDLWRLVSEGG
>W3ZYZ4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Rhodococcus rhodochrous ATCC 21198|TrEMBL
MADTEMTVAQLREWLRNWIAEATGQPVAQISDDRPMEEFGLSSRDAVALSGEVEELLGVT
LTATIAYQHPTIASLATRIIEGEPELPEGDDSAFYAAGPAGRTHDVAIVGLAARLPGHVS
TPAEMWELLAQGRDGITDLPEGRWSEFADDPQISSAIAAANTRGGYLDDVKGFDAEFFAM
SPREVEMVDPQQRLALELTWEALEHAHIPASDLKGRPVGVFIGSSANDYQLLAVSDPSAA
HPYALTGTATSIVANRVSYFFDFRGPSVALDTACSSSLVAVHQAVRALRDGDADVALAGG
VNMLVAPAATLGFDQLGVQAPDGRIKAFSADADGMVRAEGGGLVVLKRLEDAERDGDTVL
AVIAGSAVNQDGRSNGLAAPNPEAQVDVLRRAYRDARILPSGVDYIEAHGTGTVLGDPIE
ADALGRVVGRGRDADKPVLLGSAKTNFGHLEAAAGAAGLIKVVLAMQENHLPATLNYTAP
NPYIPFEQARLKVIPEGAEWPRYTGKAIAGVSGFGFGGTNAHVVVREYTGPEADAESSER
IVPSAEGAEGHIRSEQGEEHPVLLAVSAAMPSRRRRAAADLADWLETEAGSTTPLADIAR
TLSRRNHGRSRAVVIAKTRAEAIAGLRAVAAGKPAQGVFSADAPAANGPVWVLSGFGSQH
RKMAKQLYLENPVFAAAVDEIDELIEDEAGYSMKEKFLDDGQDYDVETSQVGIFTIQVAL
AKLLRHHGAEPSAVVGHSMGEAAAAYISGGLSLEDAVRVICARSRLMGEAEALLEGDDIR
LMALVEYSAAEIELVLTDYPHLEVCVYAAPTHTVIGGPQDEVNAIVARAESEEKLARVLQ
TKGASHTSQVDPLLGELAAELAGIEPHKPKVDVYSSVDQDTHYRAGHDPIHQVEYWTKGL
RHSVYFTNAVKLAVTDGHTTFVELAPNPVALMSVAATAYAAGVIDTQLIQTLKRKEDEPL
GVLTALAQLYVHGHAVDLRSLLPAGEYADLPRTVFLRKPFWLETRIGTGGNARVPGAHVA
LPDGRHVWEVRADAVTDLGELVVAAASQTLADVTLTASVPHGDVPTSGTLTTTLTRHPGG
ASLHVHGRDAASGEFRLLFDAVVASGEALPAPAAAPAPAERSSGPVETLPEVVETFGDKW
NPAGSQTLEDRLALIVAESMGYAPEDLPVEIPLIELGLDSLMAVRIKNRVEYEFDIPQLQ
LAAVKDASLRDVAKYLRYAVENREEVAALAAQQAADRETAEREDTTLELPPISAVEDTGV
VHEAEAILEAAEAAEAAEAGASTEADKATDVTDRQAVAEASGTDVPPRDAAERLTFATWA
VITGQSAKGIFNTLPILDDETAERLAARLTERANGEITVDDVLDAETIEQLAESVRRHLE
SADRIDGLVRTLRPRPEGSDAVPVFVFHPAGGSTVVYEPLLRRLPEGTPMYGFERTEGPI
EKRAQEYLPQIKEIQGDGPYVLYGWSLGGVLAYAVAKLLRAEGKDVRLVGLIDTVMAGEK
VEDTPEEITKRWQRYARFAKKTYGVDAPLPYDKLAATDDEGQVRILMDLLRMSGTRIPGG
IIEHQRTSWLDNRAIQTAKLEPYDGDVVLYMADRYHDDAIELEPAFGTRQPDGGWGEAVR
NLEVIHVGGDHLQVVDEPYIGKVGADLTRKLADIEATRS
>C6C2W6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Musicola paradisiaca (strain Ech703)|TrEMBL
MTTQNNDTKDATILTDIRDGVAGNIACPDDLFSIHKKDAVAIIGVGGFFPGADSIEDFCQ
KLDQQESLFSRVPENHFPGAEMRNRYGAFLKDIAGFDPDLFNIGPMEAEYMDPRTRLLLM
SAWHTLEDACYLPQQLREAKVDVYIASEGAAYTPFLAKAELTSYSILGMMSWSLPNYISH
AFRFNGKSLYIDTACSGASVALHQAKEALLRKDADYALVGAANLLFGDALAGSYLGQESL
GILGGATVCSPFQADAKGFLPAEATVTVLLKRLSQAVADRDNIHGVILGSDVNHTGGYGS
LTMPSAESQASVIVNAYRQAGIDANTVTYVEAHGASSLLADAEEIKGFKRADAQLNAHLA
PSDLEPSKGSPCKVSTLKPNMGHANSASGMVALVRVLHAFNTQKKPGIKDFSACSDKIRL
EGSRFYINDMTEEWPPLRDECGRDIPRRAAINNFGAGGVNAHLLLEEYPRTVDLPVHSNA
ASDETKPQGDVYFLALSTRHEWQWVHYAKSMLAFLQHAHDVPPGALEYVYLTARHKFDQR
VVFRYTSIDNLQEKLAQFIAANGQKSFYLKTGQPDENKAFDIFTRHNRLSDLLKTLDWTH
DKNFLMELWVRGVDFPLAQSVGSSGFSKISLPRYPFHLEHYWSTADTTAISPPDAGRHRM
RREIHPLVQQNTSDFSIQRYRSFFTGHEFFLADHLVKGQKVLPGVAYLELARAAITDAVG
QASRLMLENISWVRPMSVLDAGLNVAIELSPEGNDYVGFEIYSAESSVEGTGRIIHCRGQ
ARVTSLPDDETSHATPATPSPVDIHALQAQCVTRRLDSAACYRAYTAMGILHGPAYQGVV
SIDEGDSQAIARIELPACVADTRSQFFLHPSLMDSALQIAAGLLVDAGHPEFALPFALER
LEMFPRDTAAALPENLWVWARRKAGSSKADRVRKMDYDLCDETGHVWVRLSGFSSRVVDD
ASAGAVTATVSVTPEAEAEVNTETGVSREVALPAMHQPAVKMDDPVVMMPRSAAKTAKET
LREKLIPLMQKSLAKLRKLEPGQIDLKTELSQFGLDSILLTEFSNQLNRQYRLTLTPTVF
FEYPTLSEFVDYLVDVHAAAFSNQFPEQTPFVPPALIGSPKSADVGEPETTAAINEFTVS
DDASQRETFRSRGRLNPAFPRSASDKHPVAIASTAHKVEPIAIVGMSGRFPMARDLDAFW
DNLVSGKDCIQEIPKQRWDWQALYGDPVREVNKSNVKWGGFIEGIDEFDPLFFGISPKEA
ELMDPQQRLLMTYIWSAIEDAGYRAGEISGTDTAIFVGTGMSGYSSLITAAQRPIEGYSL
TGIVPSVGPNRMSFFLNVHGPSEPIETACSSSLIAIHRAVQSIGAGECEQAIVGGVNTLV
TPDGYISFSKAGMLCQDGRCKTFSSEANGYVRGEGVGMLFLRKLSVAEAAGDHIYGLIRA
SAENHGGRANSLTAPNPKAQTVLLKRAYTNAGVDPRSVGYIEAHGTGTPLGDPIEIDGLK
SAFKDLYRKTPATTDLGNRPQHCGLGSVKTNVGHLEMAAGIAGVIKVLLQLQHKTLVKSL
HAEQLNPYIKLDDSPFYVVRENMPWVAPVDVQGQALPRRAGVSSFGFGGANAHIVLEEYT
GGKATSDVGQNTGKSEPVMVILSAKSTDRLMAAARNLLTRITAENKQPPELSELAYTLQV
GREAMEQRLGIIASSIDELAEKLSEFLAGDAVIDALFLGNVRQNKEMLAMVAVDEDMMAT
LDLWFHKRKYARILALWVRGMPVDWYRLYPQQRPKRISLPTYPFATDRYWITHAHHAAMH
VAQSPTTLPPDAAILPPDVKGSAPPPPLLVHPSLAVERQRPEDKPQTDDYFSYVALWDAD
ETSSGKTMATRMADKVLVVGSRQETELEKALVNKLTGQAKRLLRISLGSDAARKTYLIGQ
DHWACDIQDENAMGHCLNEVGAIQQVFFIAGTAAQDLADAAAITASLKQNELQLLRLVKS
LQQGGAKEASIDFTVITQDNHPLSSREIRYHGAGISGLAFALAQGDHRFRVRNLDVSGRD
LQTPERREKLVQQVVNEVASERGEQIRLLSGRRYRQTFLRLDPRSFSGESGIKHGGVYLI
LGGSGTVGRVMTRQLLQHYQAKVIWLGRQPESSPAVQNALAAMETAGIRPDYLQADATDL
ASLHVAVTQIKRKYPRINGAIFAGLVFDAENTLSQTTEETFWQILQVKASGSLNFYQALQ
HEALDFLVYFSSCQAFSFSGAATLSAYAAGITFSDTLVRALQHRAAFPIGIINWGFWQAS
LAGLPASQSIFALSDADGFACFERFATLLQQGRLEQQVCLNASVPVQQLMNLHPHESVFL
SHQRQLSSTHSSFDTNSRRLINE
>D0LQX2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2)|TrEMBL
MSATKSANPSPLQQAFHVIRDLESRVFALTAEPIAILGMGCRFPGAVTSPEGFWRLLAGG
QDATSEVPAERFDIDAFYDPDPAAAGKTYTRRAGMLDSIDGFDARFFGISPREAVLMDPQ
QRLLLETTWEALERAGLPPHALEKSATGVFVGAAQSDYLRRHAYADTPKDIDVYDGTGNA
TCFSAGRISYLLGLQGPSFTVDTACSSSLLAVHLACQSLRAGESEVAIAAGVNLIISPET
FVFLSRAGNISPDGRSKAFSATADGYGRGEGCGVLVLKRLSRARADGDPILAVLRGSAVN
HDGPASGLTVPSGLAQQAVIRQACGNAGIAAERLDYVEAHGTATLLGDPVELDALGALMA
GRSAERPLWVGSVKSNIGHLETAAGVAGLMKVVLMMQHRQIPPSLHFTAPNPHVDWERLP
LRVPTALTEWQADEPRRAGVSSFGLSGTNVHVVVEEVAAPAAEAAEAETAEAADAAGAPE
PGAPEPGAPEPGVLLLSARTAPALRALVASWRERLADPALRASAPAIARAAALRRSHLEH
RLAVVGEGRAAWLAALDAYAAGEDGEAPPPGLLLGRAEPGRATRLAFVFSGQGSQWPGMG
RELFARSAVFRASVSATAAALAAHGGYPVLEAFAADAPPPDLERGDVVQPLLFTMHVALA
AQWRAWGVEPEAVTGHSVGEIAAAHVAGALTLDDAARLVTVRSELMMRISHQGAMAVLGL
PADDAATWVARTPEQLSIAAVNAPGSTVVSGQPEAVDALLAALAEAGVFARRVKIDVASH
SPQVEPLLAEYRQRLAGLRPVDGALPFLSTVTGAALPGSALDAAYWARNLRQPVRFADAV
AALERAGFDRFLEVGPHPVLTVAMAKTLAAGAVVTGSLRRGRPALEALGEALATLHVSGH
PVPWETILRAPQPPVSLPTYPWQHERYWESVRSAGAMAVEAAGDAATLAGRRVLSPGQEL
HFVDRLQLAERPYLDEHRIFDAVVVPGAFHLAALLSVARELVGDERIAFEELSFPQALVV
APAEPPRVHLSALPGEDGRVRIRRASPAPGARAGGAWVDHVTGFARALEGAAGERPAWAA
DADADTDAGLEARTPADFYERNTRRGIELGPSFRWMRALWVGPGRARATLARPEVLAGGS
AEGRAPLHPAQLDAVFQTFAAAVPEGADDAYIPFSIERLAFYGEPGDRPLRCEARYQPGD
DDAFLIGDAVVFDGQRVVARVDGLRLRRVSRAALSASGRPVWSEWLFETRWDRQAPSPAP
PASGDGDRAGDGGRWLLLAGERGVAERLADALRARGRECAIAHPGAAFARHGDDAFTLDP
SRREHLEQLVSALGEGAPLRQVVYLGGIADAAPVDAPLTWPAARAERVVAGLLHLAQALA
AAALRDPPRLRIVTRGAQRASDEGGAPDLAAAQLWGMARSLYHEHPELGFARIDLDPARP
ADGDDGDEMAALLAELLADAREDEVALRAGQRRVARIVRAARSAAAEAAPVRGDGSYLIT
GGLGGLGLRLAAWLAERGAAHIVLVGRRGVSDDQQRQALAQLRERGVTVEVVAADVGEPA
ELARALERAQQLAPLRGVVHAAGAVDDALLAQQDPARYRRVLVPKALGALHLHQLTAGAQ
LDFFVLFSSAAALIGAPGQSNYAAANSVLDALAQARRARGLPALAVAWGAFAEVGMAAAQ
DVRGARLAERGILGMRPEDGFDTLGHLLARGVAQAAVLALDTRQWLESSPALARAPRFSE
LVREGQQSGAGRSALRDLAALRAAPADERRARVERLLRQEIGRVLRIDGEQLEPQAQLGT
LGFDSLLSLELRNRLESLLGLSLSAVLLWTYPTLESLTEHLSEQLAPAPPDAARPAAEPA
TDSAEAASDAAGDAQDDLSGDSAEDDLENLSDEERAQLEERLAALTRRL
>A0A0N1NAG7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK006|TrEMBL
MRTAVVGMALRFPGADTPDGYWRDIRAGVTHVRRFTDAELAAAGFAPEEYGAPDFVAASA
PLPGIDGFDAAFFGMSAREATVTDPQQRLFLECAHHALEDAGYAQPRAGVRIGVCGSTGY
RLYSLHSYLANNLREESDSGDWQRQKQAQVGTYPDFAAPRAAHRLALTGPALNVATACSS
SLVSVHLARQALHFGDADLMVVASAALHVPQVTGHRHVRGSTISRSGTVRAFDADADGTV
GGNGVAAVVLKPLERALADGDTVYAVIAGSAVTNDGADRAGFAAPGSTGQRDAVLGALRA
AGVPADSIGYLEAHGTGTLKGDPIEFAALTEAFRLHTDRTGFCALGSTKSAIGHLDSAAG
LAGLIKAVLVLRHGEIPPLVNHTRPNPALDVTGSPFVLPTRALPWPAEEGRPRRAGVHSI
GMGGTNAHVILEEAPTPAPRPPDRGRAPALLPLSGHTPEALLASARAFRDHLTEHPGTDP
ADLLLTTALGRRHLEHRLVVTAEAGGTAAALDAFVRGVAGAYAHGVAGAAAGTGPVFLFT
GQGSGYDGMGAALAGRFPVVARTLEECAGIHRDETGEEGFLDRLLDGADGGPAEGARARG
QEAARSWDPEGARVWDTAFAQPALFALQVAQARLWRRFGVEPIAVAGHSAGEYAALCVAG
ALTLEDGLRLVCRRGRLMRDGTPAGGMLAVFAAEDVVRGLVTEVDGLELAVVNGPGQYVV
GGPPEAVAAARARLAERGTPAEPLPVDRAFHTALLDPVLADFRDACGKVRLRPTRTEFVS
GPDGVRHPVGWLPDAEHLVRGTRRPVDFAAVLRTLERTPGRPVHLEIGPDAPLTGLVRRA
RPDTAAVPTQRRGDRGLGTLWAAVARLHCAGHRLDWAALLDGSDARRIPLPPYPFQHRSY
WTGPPPTPLADDRETEDGMTEQAVLARVLALSARHLGYAPEEITAERTFVGLGADSLQLI
GMVRQLEAEFGVEIGMREILEEAGTPRLAARLIAERTGRRAVPASVGVTPDDEPVHITPD
DEPVHVTPDEEPVYATRAEVEELARQIRQLAETQTRMLGQLSEAVALLAEGREEVGG
>A0A654U2N2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDIQLANAPAVTVDQPNPSTRFNEVTRE
LQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPASSGPSTTHDDEDITTATESQLFAILD
DELGP
>A0A654TML0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MDPVLGVSVITAVLRGFGETALRGSVNGYTLFERTLADAPAVPNWSLDSGVLDDVVVTGG
AGAIGMHYARYLAEHGARRIVLLSRRAADQATVAMLRKQHGTVIVSPPCDITDPTQLSAI
AAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNFAAKVLGLAQMIELWPLRPDVRTLL
CSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRHCVAVKWGLWQAPKAGEPARGIADA
VTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAADAARLQMLLDSRQFERYEGPTDPN
LTIVDAVRTQLAAVLGIPQAGEVNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLM
GDITGDGLVAKLEDADERSHTAQKVDISRD
>A0A0E0U920|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Sinorhizobium meliloti (strain BL225C)|TrEMBL
MTVEIIGRACLAPGAKSPQALFKILRQGKCTVTRVPSDRWDLARFWHPVMGTPGKTYSFA
AGVLDHIYDFDPAVFGMSQREAMYMDPQQRVLLQLAWRALEDANISVASLHGENVGVYVG
ASSLDHANLTVDDPAAAGPYFMTGNTLSIVSNRISHVFGLSGPSMTVDTACSSSLVALDQ
AMRALNAGEIDTAIVGGVNILAHPLPFVGFAQARMLSPEGLCRAYDNDGAGYVRAEGGVV
FVLRRTDRAQRERDRSYARIVASGVNSAGRTNGISLPSREAQANLLRMIYEGNGIDANQV
AFVEGHGTGTKVGDPAEVWSIGTVIGAKRRAPVPIGSIKSNIGHTEPASGLFGMMKAVLA
LENNYLPASLHFETPNEQIDFDGLNVRVTANPIELLKGKRARLAGINSFGFGGANAHVVI
SDPDPAQAEKAATSPAGHVFLASAHTASSLENLLRDYKAAFAGATKEETRAIVAASGANR
THMRHRFAARSDHPEDIVRAIANHLEKPGSDIGETGEAAAKKAKVAFVFSGNGSQWAGMG
VEAFRENLHFRQSFTSVSALFRFHSDIVLTDLLTDPELDRKLADTKVAQPLLFAIQAALS
DSLVAMGIKPTAVFGHSVGEIAAAYAAGALSLVDAVSIVAKRSLHQDLLAGQGTMAAVML
GEEAAKAFAAERGLDDVCVAAINAHNSVTISGPANEISAFRDAARKAKIPVQILDINYPF
HHPIIDRAKEAFLSDIPDIAPRRTELAYLSTVTGAALDGTALDPDYWWKNVREPVRFQAA
AEAALDLGCMLFIEISPRPILGSYVKETIKQAAVPASVVATLLRDAGANGHDPISASMAR
AVAHGAAVDRSRVYGKRDAFIELPALPFEPVELRPAATTDATDLFGRSAKPYRLNGWRGD
PNAGSWKNHVDAHLFPDLAEHVVDGKAILPGSGFIEIAVSAAQQYHGSDEVEITNLEIVR
PLELSDSRIMELSTILSPETGDIEIRSRERLSEDDWTVHAVARSRKPLPTTSNDCPSTKG
LAKTATVTAAKAYETAKQFGLDYGPQFQLLSKAVAYGDRLIDVELKHPRASGHPHVTYAL
HPISVDATFHGLVALFDRFTGDRGGAPYIPVRFGSVRVVNAGRPIARATIEIERVSANSI
KARFHFFDETGVAIAHFEDCRFRRTYLRKHKTLEGLSFHYEAVLSDVVMPGTKVATAMPA
TLAEPIDDNGVDNATLLFNAAIYRACQEIALKLGRGTATVRGDALPGDFAFQCFLTSCLL
TLEDAGLCEHQNGNWKVAREFSLPTVPEILGELYGDRPDRAVEAVLVNNAYAEALSRLDA
LLGPVRAGDDAVSFNAGFISEATLDHQAVHSVASRSRMDQVLHTVEHVLAAQPAGARLRL
IELGSVSAGFSRRLADLAARNGAALSIFEPRDNAQRNLEIAFEEDAHVRVLKKSEFADIG
PFDLAVSASDNLYQVIEEESGVRTALRSMPPGSGLVAAVSAPSIFADFALGLSGGWFERS
QTAEFPIGRIAAVPHWQKCLADLDLGDVVVTDRECPHGNTILIEARGTAAAGAGAEPGET
TTPYLLIETATAQKPVAAGGRSAAPVRVTGDLAADMATLRAALEAMGDRPVRAVFMSEAE
RAVGDGSALLQTRVLALSAFAEALKQHLAGVEPEGDDRPRLVLVAPGGAPLSASAGSGLN
SGLWAFARVLQNEYEFIDVHTLDLAGDADIGRKDMLAAALPLLTVSGQNREWLLDRKTGL
LSELRAVPGATNKADGKTNAFAAATIRQRVSSQVASIAWEEASVPEPGPNEVVVAVAATG
LNFRDVMWAMGLLPEEALEDGFAGATIGMELSGHVVAVGEEIDDLAVGDAVMAIASAAFS
THAVVARAGIAKLPRALSPVAAATLPVAFLTAYYAIVELGRIQAGETILIHGAAGGVGLA
ALQVAKLKGAKVIATAGTREKRRFLTMLGADHVFDSRSLGFVEDVRSVTGGEGVDLVLNS
LFAEAMEQSLSLVKPFGRFLELGKRDYYADSKIGLRPFRRNVSYFGIDADQLLVNAPDLT
RRIFMEIGALFEEGKLTPLPYRAFDYDEIGNAFRLMQNAGHIGKIVVLPPVAGRHEVTAK
AVRGMKVDPDGVHLVVGGIGGFGLVAANWLVEKGARRIALCSRRGQPDAETRAMIERWQN
GGVAASVHACDITDAAAVETLLATLRSEAPLRSVVHAAMVLDDALIGNLSRERNRPVIET
KAKGAAILDRLTRGDRLDNFILFSSATTLVGNPGQANYVAANGYLEGLARARRQEGLAGL
AVGFGAIADAGYLTQNADVNDLLAKRIGKTALKAQVALDMVENHVAADPGTVDAAVVMIS
EIDWTAARNLPVARNALFEVILRSADQHAAGAEGTTMDLVAMIEGKSPQEAEDILFDLVA
GEIAAILRVSKDTVTRGKILKEIGLDSLMAVELGMSFQQNTGFDMPLSGVADNTTVGDIA
RKLHEKVSKRDQGNENENEAGDDKLVTELTQRHVGADKEKALSQ
>B7JWG2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Rippkaea orientalis (strain PCC 8801)|TrEMBL
MNNQPDTLNQLSPLQKAALAVKEMRAKLEAMEESLGEPIAIVGMGCRFPGGYHDPDSFWE
GLCQGIDATREIPRDRWNVDAYYDPNAETIGKSYTKRGGFLERVDEFDADFFGLTPREVT
LMDPQQRLLLEISWEALENAAIAPNQLMGSQSGVFLGISVNEYGHQTLGGNPEAIDVYTA
TGNALSIAAGRLAHYFGFQGPALVVDTACSSSLTAIHLACQSLRKRESNLVIAGGIFLML
SPHSLVSMAKLKALSADGRCKTFDASADGYGRGEGCGLVVLKRLSDAVAENNRILAVIRG
SAINQDGRSSGLTVPNGQSQQACLRSALRDAKIDPSSVSYVETHGTGTALGDPIEVKAIA
EVYCTLKNRKTPLSIGSVKTNIAHLEAAAGVASLIKVVLGLNHQKLPPHLHLKRLNPHLE
GLSINIPTVLTPWTVEAGQKRVAGVSSFGFSGTNAHVVVEEWNGQQLTGNRQQETGNFPY
LLTLSAKNNEAFKALASRYQQFLVNHPEIALGDVCFTANTGRSHFNYRGAIVAETREEMI
QQLSEFALLGVDETQKMTPKIAFLFTGQGSQYVNMGYQLYQTFAVFRDALNDCDNLLKPY
LDKSLLTIIYPVEGTNNSQNTTLLDQTIYTQPALFSLEYALVKLWQSWGIKPDIVMGHSV
GEYVAACVAGIFRLEDALKLIAQRGRLMNELPQTGSMVAVFASETIVKEFIVSWQDKVSI
AAVNGSSSVVISGDKEAIKRIVAKLESQGIETRQLNVFNGFHSPLIEPIQDQFYEVAKTI
NYHHPNLEIISNLQESPEQMASADYWCRHLREPVQFFAGIQTLRNQNYQLFLEIGSSPTL
IKMGQRCFDQPIGTWLPSLEPKQADNFVILNSLKMLYSQGITINWQQFYQDFSYQPIALP
TYPFQRQRYWHQKASSYQDKSSSQFSLFPLLDQRISSPLKPIQLTSQVNLQRLPLVRDHC
INGMPLMNLVVYLEMVFEGVKAVWGKSISQVDNFKIVQALIFSDENSRNLQLIFTPEDEQ
TLTFEIFSSLVSNSFDLETEDNFNKTHDHWILHATGKIVLGELESAKKDLNSLVFDNLSD
QYSETLSGQEFYQQIQQKGIILGESCQQIQQIWRNNGEAIARIKTMGETPYILPLREIDA
WIQTFLATFNQDSDLYLLVGLESFRFYTYPQHSPPRNWMGQAKLTPSRYQQETIFGTLSL
LTEDGYLVGEIINAELKRINVDKTQLKPQNSFSLVPQIPKITRESLLEANPIDCQSMLQS
YIQATLANSLQVSLTAIDPQQSLIYLLDSLMAMELRSHLEKDLGLSVSLEYLLGDRNIQQ
LTTLLLDQLAIATMTPSTEFTDDMEEILL
>A0A2K8QWY0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MSETKLRDYLNRVTTDLHRTRQRLREVEAKQREPIAIVAMSCRFPGGVSSPEELWRMVAD
GADGLSPFPKDRGWHEEVYNPDPDSQGTSYVNEGGFLHDAAQFDPVFFGISPREALAMDP
QQRLLLEVSWEALERAGIDPLSVKGTTGGVFMGAAFQGYGAAGPIEAEEVEGHLMTGQTP
AVTSGRISYVLGLEGPAVTVDTACSSSLVTLHLAAQALRQGECDFALAGGITVMAGPGTF
TEFSRQRGLASDGRCKPFAAAADGTNWSEGVGVLLVERLSDARRHGHPVLAVVRGSAVNQ
DGASNGLTAPNGPSQRRVIRQALDNAGLTPDDVDVVEAHGTGTSLGDPIEAQALIASYGQ
DRPEGRPLWLGSIKSNIGHAQAAAGVAGIIKMVMAIRHGVLPKTLHVDEPTPHVDWSAGA
VELLTEARPWPEIDRPRRAAISSFAISGTNAHTIIEQDLEAEEPEQAGAEAPAPVAAPVV
PWLVSGKGEAALRAQAERLHARLTAQGSAQDDELAVASVADIGYSLAVSRSAFEHRAAVI
GDDRESLLRGLLAVAQGEATPGVVRGQAAKGRRTAFVFPGQGAQWAGMAVGLLDSSPVFA
EAVAECEAALSAHVDWSLTEVLRGAEGAPGYDRVDVVQPVLFAVMVSLAKLWRSVGVEPD
AVMGHSQGEIAAACVAGALSLEDAAKVVALRSQAIAVGLAGRGGMVSVGLPVDQVKERIA
AWDGAISVAAVNGPGSVVVSGDPGALDEMVAQLEGEEIRVRRVPVDYASHSAHVEGIREE
LLKALVDIEPRSSEVPFYSTVSGEVVDTAGLDAEYWYRNLRQTVELEATTRTLLKDGLTV
LVEVSPHPVLTLPVQQTVEAAEARAVVVGTLRRDEGGPERFLTSAAELHISGVGVDWRKV
FQGRGARRVELPTYAFQRQRYWLDATAAVGDAGSVGLGPVWHPLLGAVVSLAGGGGVLLS
GRLSMATHAWLADHTVEGVALVPGTAFMEMAVQAGDQVGCARVEELVLEAPLVVPERGGV
QIQVEVGDVDAAGHREVSVYSRIESDEDRADLGNPWVRHAHGVLTPPGPAASFDFKKWPP
SGSKPVDISGGYEHAAEHGLRYGPAFQGLRRAWRRGDAVFADVELPEEQLGTAKYFGLHP
ALFDAALHAIGVSKSMRGGDDAPSAGTLLPFSWRGFSLEAVGAGALRVRMVPDGRQAVSL
AIADTSGRPVASVDSLVLRPIQAQALRNAGRTNGDALFRMEWTADAVKPTESVAPGWSAV
LGDDLLGVGAALEMSGVTVDVYTDPVALGDAVSSGTLMPGMVVLPVVPGGAAVVDEVHTR
VAEALETVQSWLADERFAATRLVLVTRGAVDTGDGVTDLAGAAVWGLVRSAQSENPGRVV
LVDTDDVEKSAGLLAGVAASGEEQVVVRSGEVRVPRLARSLPSGDAAEAATFGSGAVLVT
GGMGVLGGLVARHLVARHGVGKLVLLSRRGAEADGAAELRAELEAAGAEVMIAACDASDR
EALAAVLSGLPEEFALSAVVHATGVLDDGLFASMTRERVEPVLRAKVDAAWNLHELTAGM
DLSAFVLFSSAAGVFGSAGQSNYAAANVFLDGLASWRRAQGLPGVSLAWGLWEQASGMTG
HLGQGDLRRVSRSGLVPLSSKEGLELFDEGVTSGPAVVIPTRLDLGALRAQGAAMPAVFR
AIVPESAVRRTARAVESEAGDQPTQLRQQLAGLSKAETEEALLELVRTLAAAVLGFASPD
DVDTGHEFMEMGFNSLTAVEFRNQLAAVTGLRLNTTVVFDHPSPLELVSYLRPRLAAEIA
SAPAGGQVREPSAPAAAPAAAPAPEAVSPAPQADAPDTLGSLFRQAAEQGKTKIGMDLLV
NAARLRPTFEDPADFEGNIRPVRLSRGAERPRLMCFSSYMALGGVHQYAQLAAPFRGSRD
VAALPAVGFVQGESLPATPEAFFRFQARVVSEYADGAPVVLLGSSAGGMIAHSVAAALES
EGTPPAGVVLLDTYLPYSASIGQFENAMLDEMYEREALVSMEGVRMSAMGWYLHLFEGWK
PPESSVPSLLVRAADPLGEVDPDASAADWQSDWPADSAVDVPGNHFTMMEKQAGTTAQAI
EDWLADL
>A0A2K8QXU6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MAEDEKLLDYLKKVTADLRQARRRLRQVEERDREPIAIVAMSCRYPGGVKTPEELWRLVA
EGGDGVTEFPPDRGWDVDGFFDPDAERSGTFSVREGGFLDTPGDFDPGFFSMSPREALAT
DPQQRLLLETAWEAFERAGIDPASVRGSQAGVFVGASPSGYGAGVSEMPEGVEGLLLAGN
ATSVVSGRVAYTLGLEGPAVTVDTACSSSLVALHWACQALRQEECSMALAGGVAVMFTPS
MFVEFSRQGGLAPDGRCKAFGAGADGTGWAEGVGLLLLERLSDARRNGHPVLAVVRGSAI
NQDGASNGLTAPNGPSQRRVIRQALKNAGLTPADVDAVEAHGTGTSLGDPIEAQALLATY
GKERAEDRPLWLGSLKSNIGHSQAAAGVGGVIKMVMAMREGVLPKTLHADEPSTQVDWSE
GDIRLLNESVPWPETEQPRRAGVSSFGISGTNAHAILEEAPEAEEAEEAEAEVADGPVAW
VVSGRSAAGLRAQAGRLREFLAERPELGATDVAHSLVATRSVFEHRGVVTGVDREQLLER
LGALAGDEVASGVTRGVADVRGRSVFVFPGQGAQWMGMAVGLLESSPVFAEAIGECETAL
SAYVDWSLTEVLRGAEGAPGFDRVDVVQPVLFAVMVSLAKLWRSVGVEPDAVMGHSQGEI
AAACVAGALSLEDAAKVVALRSQAIAAGLAGRGGMVSVGLPVDQVKERIAAWDGAISVAA
VNGPGSVVVSGDPGALDEMVAQLEGEEIRVRRVPVDYASHSAHVEAIHDELLKVLADLKP
RTSEVPFYSTVSGELVDTAGLDAEYWYRNLRQTVELEATTRTLLDTGHAIFIEVSPHPVL
TLPVQQTVEAAEAQAVVIGTLRRDEGGLERFLTSAAEVFARGTKVDWAITLEGRGARRVE
LPTYAFQRERYWLDGFGLPPGGGAADGTGSVDERFWDVVQRQDLESLAGALAVDSEAPLS
AVLPALSAYHRNNRDQSTIDGWRYRVSWKPLSDAADGSLSGTWLVVVPASRAEDELVSGV
LAGLERHGAGVVPVAVDERDLDTDVLAERLRQAAAEAPELGGVLSLLALDERPCPGHPAL
TGGYALTLVLVRAMVEADVPARLWCGTRGAVSVGRSDRLTSPAQAMIWALGRVAGLELPP
LWGGLVDLPESLDRRGAERLAGVLSVEGGEDQVAVRGSGVFVRRLVRSAAAVGEGTSWRA
RGTVLVTGGTGGLGGQVARWLVRSGAEHLVLTSRRGLEAEGAAELKAELEGMGAEVTVAA
CDAADRDALAAVLDAVPEHRPLTAVVHAAGVTLAASLLETELADAATVVSGKVAGAVNLD
ELLGDRELDAFVVFSSISGVWGGGSQGVYGSGNAFLDALVERRRARGLAGTAVSWGPWAE
GGMATRDDAGEQLARRGLPAMAPQLAIAALERAVAGDDGVVTVVDVDWERFAPSFTAVRP
SPFLSDLDEVRALETKGGDGESADAAGAQLRERLKPLTEGERDRALLDLVRKHAASVLGY
ASAEMVEPNRAFRDLGFDSLTAVDLRNRLAAETGLGLPATLVFDYPSAGVLAAHLRAEVL
GTTSPAPTTGSGANSGSGADDEPIAIVSMSCRLPGGVRSPEDLWQLVDGGGDAISSFPSD
RGWDLSGMYDPDPDRPGTFYAREGGFLYDAGEFDPGFFGISPREALATDPQQRLLLETSW
EAFERAGINPASVRGSQTGVFVGFSGSGYGTNLETVPEDVEGHLLTGNAGSVVSGRLAYT
YGLEGPAVTVDTACSSSLVALHLACQSLRQGECDMALVGGVAVMATPMAFVEFSRQGGLA
PDGRCKPFAAAADGTGWSEGADVLLVERLSDARRKGHQVLGIVRGSAINQDGASNGLTAP
NGPSQQRVIRQALASAGVSAAEVDAVEAHGTGTSLGDPIEAQALLATYGKERPEGRPLLL
GALKSNIGHTQAASGLAGVIKMVMAMRHGVLPKTLHVDEPSPQVDWTAGEVRLLTEATEW
PETGQPRRAGVSAFGVSGTNAHTIIEQAPSEAEDTRPAESTAPDDRGVAPWTLSARSADG
LRAQARRLRAHLTARPELSLKDIGYSLVATRSVFEHRAVLTGADRAELLRGLEAVATGEE
APGVVRSVATPTGITAFLFSGQGAQRVGMGRELYEAFPVFARALDEVCAHLDVLLDRPLK
DVMFAAEGGADAELLDQTAFTQPALFAIEVALFRLLSAWGVAPDVVIGHSIGEIAAAHVA
GVFSLEDACTLVAARGRLMQALPEGGAMVAIEVSEEEIAPSLTGRAAEVSIAAVNGPNAV
VIAGDEAAALEIAEQWSEQGRKTRRLRVSHAFHSPRMDAMLDDFRKVVEGLSFAPPAIAL
VSNLTGKSAGADEVCSPEYWVRHVREAVRFLDGLRSLENAGVTRFFEVGPDGVLAAMARE
CLTAEEASAPVVVPALRKDRPEAQALTTALAELHVHGATVDWEAMFAGQDVRRVELPTYA
FQRQRYWLDAPESGGSDTAAVDSVDARFWDAVEREDLEALTAALHVDGNASLTEVLPALS
SYRKGHRERSTVDGWRYQIAWNAVSELAERALTGTWMVMVPAPYADDELVTSAVTMLERQ
GADVARIVLDGAADIDRGAVAERLRTAAEGASDGAVSGVLSLLALDESPSPEHTVVPQGL
ALNLVALQALVDAGVEAPLWVATRGAVSVTGSDTLRSAAQAQIWGLGRVAGLEHPRLWGG
LVDLPETLDERAANRLSGVLGGGAGEFEDQVAVRTSGVFTRRLVRAAAPRTTARPWSARG
SVLVTGGTGGVGSQVARWLAGAGAEHLVLASRRGPEADGAAELRDELTALGAEVTIAACD
TADRDALAAVLAAIPERYPLNAVVHAAGVLDDGVLDSMSVERVAGVLRPKVAGARHLHEL
TEGLDLSAFVLFSSLAGAIGGAGQGSYAAANAYLDALAQQRRAQGLAATSVAWGPWAEGG
MAVDGALEDRLRRGGMAAMTPELAVMALQQALDLQETHLAIADLDWERFVPSYTAVRASR
LLDEMPEARRILEAATAGGASAQFETGGSELRERLAGLPEAEQERALLDLVTTQVAVVLG
FPSVESVESQRAFRELGFDSLTAVELRNRLDAATGLRLPATIVFDHPTPVALARRLRTDV
VQDGVSAAAPILGELDRIEAAMATISADDVDRPRITTRLQTLLLKWGEAEQDSRNSGKKA
VSDKIQSATSDEIFDFIDKELGIS
>A0A2K8QXK8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MSNEEKLLDHLKWVTAELRQTRQRLREAESAEPKPIAIVGMACRYPGGVRSPEELWRLVR
DGEDAVSGFPTDRGWGTEELFDPDPESYGKSYVDQGGFCYDATEFDAAFFDISPREAQAM
DPQQRLLLETAWEAFERAGLTQESLSGSNTGVFAGVGSHDYLSVIGNITSEVEGYVGAGN
LGSVVSGRVAYSLGLEGPAVTVDTACSSSLVAIHLACQALRNGECDLALAGGVAVMATPG
GFIEFSRQRGMAPDGRCKPFAAAADGTGWGEGSGLIVLERLCEAQRRDRRVLGVIRGSAV
NQDGASNGLTAPNGPSQQRVIRQALANAQLSTAEVDAVDGHGTGTTLGDPIEAQALLATY
GQGRPEDRPLWLGSIKSNLGHTQAAAGAAGVIKMVMAMRHELLPASLHIDEPTPHADWAS
GAVRLLTEPVPWPRGERARRAGVSAFGISGTNAHLILEQAPAPAGTPSVTTVPTDGDGVP
AGGVVPWVVSGRGAEALRGQARALAERVATDPDASPAEVGWSLISTRSVFDHRAVIVGEH
RDELLAGLNALATGDTHPTLTEPTTGPGVGGMGPVLVFPGQGSQWLGMGAGLLDTSPVFA
ARVAECEHALTPHVDWSLTEVLRGGVNAADLARVDVVQPVLWAVMISLAAVWDHHGLTPT
AVVGHSQGEIAAACVAGALSLDEGARIVALRAHALRRLAGHGAMASLTTSQTHTEELLTN
LGEPAREVGIAAVNGPGSVVVSGPPEQVAHAITACEQAGHRARLIDVDYASHSAQVDEIA
EELREVLSGIEPVQAEVAFYSTVTGARMDTSGLDTAYWIKNLRERVRFADAIQALLHDGH
RVFIEASTHPVLTIGMQETFEEAGVPAAAVPTLRRDHGDQAQLMRSVAQAFTAGVAVDWT
RWFRTDPAPRTIDLPTYAFQRRRYWLDGRGGHSGDPGDLGLGSAGHPLLGAAVELAEGGA
HLLTSRLSPRTHPWLNDHRVLDTALLPGTAFAELALHAAARTGCDLVSELTLHAPLVIPQ
GEAVDVQIAVAAPDHTGERPITVHSRPVAEEDEGAWTRHATGALATSPPANAVSLKGAWP
PPGATPLPVDDFYRQLADHGYHYGPSFQGLTAAWRLDGDVYAEVSLPEGEREGAAAYGIH
PALFDAALHARALDVAPGSEDARRILLPFTWSGLRLCATGADTLRIRITPTAPDRLALLA
ADPTGAAVAVVDDLILRPVPDGQLGRARAAGRNSLFQLVWTRMTPTTPAPTCRSAVIGPD
GDPPADALRDAARLPDLAAVRATVAGGAPPPDVVFASFGSSVDGRGDPGDPGDPMERTHD
LGKEALGVLREFLATPEFADARLAVVTRGAVATQSHDDVHDLPASAVWGLVRSAQSENPG
RVLLLDLDERDTSLRSLPDAVASGEPQLALRDGVAYVPRLVHDEAAKRLTPPEGAATWRL
GLTGHGSLDQLALVDCPDNTRPLDRGEVRVALRAGGVNFHDVVVALAMVEDPRPLGGDGA
GVVVEVGPGTGGFAVGDRVMGLFNGTGPLVVTDVRMITKIPEGWSYAQAATTPSAFLTAY
YGLADLAGLRAGEKLLLHAATGGVGLAAVQLARHWQAEVYATAGPTKWHALRERGFDDRH
IASSRTLDFEERFRAAAGSVDVVLNSLAGDFVDASLRLLGPGGRFIDMGRTDIRDAEQVA
VRCPGVAYRAFDLVGGAGPDRIQQMLAELSALFENGTLRPLPTTLWDIRRAPEAFRHFSQ
ARHIGKIVLTLPSALDPEGTVLITGGTGTLGAATARHLVAHHGVRRLLLISRRGLDTPGA
TELAAELTGLGAEVSIAACDAADRAALAKLLETVPGRHPLTAVVHAAGLLRDATVEALTP
DQLDEVLRAKADAAWNLHELTRDAGLSAFVLFSAAAGLLGAAGQGNYAAANAFLDALAVH
RHAQGLPATSLAWGYWAEATGMTGGMTDTDRARLARSGMVGLETEQGLALLDIALDSGLP
ALAPIRLDLAGMRREAHADDLPPLFRSLVRGATPQAATGAAGPGGAAPAEAFAAMSEEDR
QQALLKLVRGATATVLGHDTADAIHPAQNFRELGFDSLTAVELRNRLGAATGLRLPATLV
FDHPTPTAVVRLLRELLVPAGVTPTDSLLTGLDSLDTALTGGIADGERRARIAARLRELL
RKVDGPWQGAEGDDPAEEDLASASDEELFQALDNELTVPSDDSLR
>A0A2K8REA9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MADSKTLTDYLKWVTADLYRTRERLAEVESASAEPIAIIGMACRFPGGVTSPEALWELVS
SGTDAISGFPDDRGWDLEGFFDSDPAQEGTSYMREGGFLTNATGFDPAFFGISPREAVAM
DPQQRLLLETTWEVLERAGINPTSLRGSRTGVFTGLMANSYTTRVRRIPGELESYAGNGE
AASVASGRVSYTFGFEGPAMSVDTACSSSLTALHLAVRALRSGECPLAVAGGVTVFATPR
IFSDLSRQRGLARDGRCKAFSTSADGTGLSEGVGLLLVERLSDAQRLGHPVLGVVRGTAV
NQDGASNGLTAPNGPAQQRVIKAALADARLTAADVDVVEAHGTGTKLGDPIEAQAIIATY
GQDREQPLWMGSLKSNIGHSQAAAGVAGIIKTVMAMRHGVMPKTLHVDEPTPEVDWSAGA
VEVLAEARDWPGADERPRRAGVSSFGVSGTNAHVILEQAPPAPEPTESAEPVEPSEAAEP
SGPVGLELEPSGPVPWVLSAQNETALKDMARQLVTETEGSVHQIAHSLITQRSATLPHRA
VLVGSTREEFATALDNLTGHTFDGGKTVLVFPGQGSQWVGMGQRLWETSPLYRDTIHEVD
AALSEYIDWSVTDILTGQPGAPTWDRVDVIQPVLFTTMVALATLWQHHGLTPDAIIGHSQ
GEIAAAYTAGALTLQDAARITTLRSKALLPLTGHGTMISVLAPPEKIQEIADPDHWNTRI
WIAAHNAPNTTTITGDTQAITHLTQQLSHHRIMRWQLPGVDFAGHSGHIDQLHQQLQEIL
APITPQKPTTPFYSTTDNTWITDTTLDADYWYRNLRQPVLFQPAIHHLTNNGYTTYIETS
PHPTLTPSIQETNPDTTTIHTLRNEQDDTHAFLTALGHAHTHGHPITWHTLIPPTKTTPL
PTYPFQHTHFWLNEKTADADVESAGLSRTDHPLLGATTTLAHSGETVLTGRLSPTQHGWL
ADHAVNGTPLLPGTALVDIALHAGDHTNHTTLDELIIHTPITLTHPTTIQLTTTPTHDNN
TLNLTIHTRTTPEQPWTAHATGTLTRANTTPPSPQTTWPPANAEPIDLTGTYQRLATTGL
EYGPTFQGLHALWRRDSDNRLLADVRLPDSIDNTDGYGIHPALLDAALHALVAVSDGDEI
RLPFAWTGVTLHATAATKLRVELDIDDDGTLSLSATDTSGQPVVTVDSLTTRPIDPAQLR
ARPRQTDDLYALDWLPWSGSVSPTSEFERYAVPTVGDDVLADTHRITTETLTRVQQHLAA
DTTTPLVVEATYDDLAGAAVWGLIRTAQTEHPNRIVLVDTDNHPASRDALASMVASGEPQ
ARIRDGAITLPRLTTTAVTDALTPPADADAWHLDTSERGTLENLTLTGSDTATRSLLPGE
VRVAVRAAGLNFRDVLIALGMYPGEATMGSEAAGIVLDIGPDITDLTPGDRVTGLFPNAL
ANVVIADRRTITPIPADWSYTDAAAFPIVYLTAYYGLHDLAALKPGERVLIHAGTGGVGT
AAIQLAQHLGAEVFATANPTKWPHLRAMGLDDHHIATSRTPDFETTFHTTTQGQGIHVIL
NSLTDNLTDASLRLLTPNGRFIEMGKTDVRDTEDLPEGITYQAFDLALDAGADRIAGMLA
ELVELFGSGALSLPPVRCWDVRESVDAFRFMAQARHIGKVVLTIPHTPDGTILITGGTGN
LGSLIAHHLVTTHGARDLVLTSRQGPNAPGATELTNQLQQHGARVRTISCDLTDRTALAT
LIDDIGPLTGVIHTAGALADTTIDHLNADALTTTLTPKANPAWWLHELTQDHDLALFVVF
SSSAAVLGSPGQANYAAANSFLDALITHRRRHGLPGTSLAWGWWQRTGAMTAHLTQADHD
RMTRAGLYGITEAEGTALFDTALGRGLGAVAPVKLHLPTIARSGSVPPVLRALVRAARPT
ASQAAVQDGTWADRVAAVAPEERRAVVLELVRAQAATVLGHSGAEHVSPTQAFKDSGFDS
LTAVEFRNRVTTATGLRLPATLIFDHPTPNTLADHLLAQLAPADTGPSLADLDGIEVTLR
ALAEDGERRPAVVARLKQWLSTLGAAQPAADTALDLDAASAREIFDFLDGKAG
>A0A445NHW9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces netropsis|TrEMBL
MTNEDKLRDYLRRVTAELQTARQRLRDVEERSAEPIAIVGMACHYPGGVESPEDLWSLVA
EGRDGITPSPADRGWDLDALYHPDPDHPGTTTVREGGFLHGAASFDAGFFGISPKEALHT
DPQQRLILQTSWEAVERAGLDPTVLRESRTGVFTGVMHHDYPGAQGAGSVVSGRVAYQLG
LRGPAITVDTACSSSLVALHLAVRSLRRGECEMALVGGATVMATPTGFIEFSRQRGLAPD
GRCKPFAAAADGTAWSEGVGVLVVERLSAAVANGHRVLAVVRGTAVNSDGASNGLTAPNG
PAQQRVLREALADAGLTPEQVDAVEAHGTGTPLGDPVEAQAVLAVYGKQRKKPLRLGSVK
GNLGHTQAAAGVAGIIKTVMAMRHGVLPRTPHLDAPTPYVDWSAGAVELLTDDVPWPAGE
DLRRAAVSSFGVSGTNAHVVLEEPPVIKDGAEHEAGTEADDRAEDAAAGPWAWPLSGRSA
AGLHAQAAALAGFLADRPELHPRDVAFSLATTRAAHEHRAVVLGTDSSELLAALTELAAG
RPSPAVVEGTTGPSGPVAFLFPGQGSQWRDMAVRLLDTNEVFRARIAECEAALAPHVDFE
LTAVLRGEGDLDRVDVVQPALFAVMVALAEVWRSLGVRPAAVVGHSQGEIAAACVAGALT
VEDAARVVALRSRALTAISGRGGMMSLALPAEDARERLRRWEGRLSLAAVNGAASVVVSG
DTDALDELLAACEADGVRARRVDVDYASHSAHVEAVREQVLEALAPVRPRAPEVPFFSSV
EGRWIDGADAFDADYWYRNLRETVRFDEAVTALVERGCGTLLEVSPHPVVTNGAQETVDS
LGTDTAVAHTLRRDEGGPEQLLLALAQLHVKGVRPDWSAVWPGARRVELPTTAFVTEPYW
LRTAAGTGDATALGLDNVDHPVLRAALSGAEGVVLTGRLTLAAQPWLADHTVEGHIVVPG
AALAELVSRAGDEVGCAAVDQLTLLTPVVLPDDADVRLRIDITGQDRDGSRGLTLHARTG
AGHWTTHATAVLLPAGDEPPAAPAVWPPSDAEPLDVEALYARLEEAGLAYGPAFRGVRAL
WRGQGGDLFAEVALPGADGSDGFTLHPALLDACLHPVALGGFLTQEHGRPSLPFEWQGLR
VHAVGADTVRVTLSAAGPDAVRLALTDPSGAPVASVDTLVLRELPAGALNRPDRGDLLRP
EQVARTLPDATGDDEDYAVRDADLARLLKKQPSQDAARFVLVPAPTGDPADAVRDALRLV
HDWVADDGNSETTQHPAPTLVVVTRRVHDDVAEAAVAGLVRSAQLEYPDRFLLLDLADDE
DATLAAVPAALAAGEPQITLASGAASVPRLVRAAPATREAADLGTTLVTGASGTLGRLVA
LHLVHTRGVRELVLASRRGTQAPGMTELAEELTEAGATVRVVACDVADRAALAELVGTAA
FTTVVHAAGALDDGLVTDLTPQRLPRVLEPKLDAARHLHELLPEARLVLFSSAVGVLGGL
GQANYAAANAGLDALARLRHARGLPGVSLAWGLWDATSEMTEGVDRARFGRSGFLPLPTA
DALAALDAALASDEPVLAPIRLDTAALRAQGEAVPVPLRDLLGAPARRTATPGGPVADSE
LAGRLAGKSGADRRRILLDLVVGHTAAVLGHTSPDLVDPDRAFKDAGFGSLSAVELRNRL
AGATGLRLPATLVFSHPNPAALTRHLDELLAGAAPATAAVTAPGTTADADDPIVLVGIGC
RIPGGVRSPEDLWDMLVAERDGISPFPDDRGWPLERLYDADPAAAGSSYVRHGGFMTDAT
AFDAAFFGVSPREALAMDPQQRLLLETVWEACEDAGIDPATLRGTRAGVFVGAMYQDYGR
LLENAAAEGFLAPGVGGGVLSGRVAYTFGLEGPTVTVDTACSSSLTALHLAAQAVRAGEC
DLALAGGVTVLSTPVPFVEFSRQRGLAVDGRCKPFAAAADGTALGEGVGVVLVERLSRAR
ALGHEVLAVLRASALNSDGASNGLTAPNGRAQEQVMRAALAAGGLRPTDVAAVEAHGTGT
ELGDPIEAQAVLAVYGQDRPEPLRLGSLKSNIGHIQAAAGIAGVIKAVLAIRHGLLPRSL
HIDEPSPHVDWSTGDVALLASAEPWPEQPGPRRMGVSSFGISGTNVHVVIEQAPPVDAPE
TLPALEGVPWLLSARSEEALRAQARRLLEADTSDPAAVARALSTTRSAHRHRALVTGSDE
PGTRAALTALAAGRAADGLRRSTASRQRLTLLFTGQGSQLPGMGRGLYETFPVYAEAFDE
VAAHFDLETGLREVVFEREDLLDRTEYTQPALFALQIAQFRLLSSWGVVPEALVGHSIGE
LSAACVSGLLPLADAATLVAARGRALGALPAGGAMVSVRATEEDVLAVLDGRTGQVEIAA
VNGPRAVVLSGDEEAVLAAAKELADRGHRTRRLRVDVAFHSPHVEPALDGFRAVAETMRF
GQARIPVVSTVRTDRAMDTPEYWVDQLRGSVRFADAVQQAHEKGATAFLEVGPDAVLAPA
AEVCLPDTVVRPVALLRRGRDDVRAATEALALLHTHGVDVDWTAVHAGRPAHRVPLPTYA
FNGRRYWPEPAVAQQPEPAAPAVTTDATLDPFWSAVDGADVTTALGLLDLRGDETPAQVL
AALGRLRFGVSAPVMERARWTPVPDASAPVLAHDVLLLAPDGGDDDLADAIAGVLVRHGA
RVRSGGGERPDLVVALPGAEPVAEPGVPRWVLTDGGTAPEGDHVVTLPQGIDARVRARLC
AAIADGHRETLIQADGRFVREYEPVTPAGQWRPQGDVLVAGPSDALTEAIVDAVLRAGAR
CLVAGGVTCPPGAVKFGGAESPVRLTAAIVRAGTGFDDVAAPLVTVVSVGDRVAATAREA
GGDGSAVRVVAVGPGLDPRAAVLGLCRAIATDEPAVRLLAPTVAPALTTDTPTPVAAGAP
ETVPPVAEPDTAQPAPVEPSAEPSAEVASADGQSEAPGSQDSELRATLAKLPPERWAEAV
LGGVQTLAAAVLGYESATEIGAEDEFFDLGLTSVTALELRDHLATLTGLDWAADVLYECP
TPRVLTDLVVERMTEETG
>A8H6N8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Shewanella pealeana (strain ATCC 700345 / ANG-SQ1)|TrEMBL
MSQTSKPTKSAKVTEQAQDSQADSRLNKRLKDMPIAIVGMASIFANSRYLNKFWDLISEK
IDAITELPSTHWQPEEYYDANKSTPDKSYCKRGGFLPDVDFNPMEFGLPPNILELTDSSQ
LLSLIVAKEVLADANLPEGYDRDKIGITLGVGGGQKISHSLTARLQYPVLKKVFASSGIS
DQDSEMLIKKFQDQYVHWEENSFPGSLGNVIAGRIANRFDFGGMNCVVDAACAGSLAAMR
MALTELTEGRSEMMITGGVCTDNSPSMYMSFSKTPAFTTNETIQPFDIDSKGMMIGEGIG
MVALKRLEDAERDGDRIYSVIKGVGASSDGKFKSIYAPRPEGQAKALNRAYDDAGFAPHT
LGLIEAHGTGTAAGDAAEFAGLCSVFRDENDTKQHIALGSVKSQIGHTKSTAGTAGLIKA
ALALHHKVLPATINVSQPSPKLDIENSPFYLNTETRPWLPRADGTPRRAGISSFGFGGTN
FHFVLEEYNNEHSRIDSEKAKYRQRQVAQSFLVSASDKATLINELSTLSASATQAEFILK
DAAANYPLRELKANAPRIGLVANSSEELVNQIKQAVSKLESSDDSAWQLPGGTSYRANAA
IDVANKESGKVAALFAGQGSQYLNMGRELTCYYPEMRQQFVTADKVFAANNKMPLSQTLY
PKPVFNKDDLKTQEATLTNTANAQSAIGAISMGQYELFTAAGFNADMVAGHSFGELSALC
AAGVISSDDYYKLAFARGDAMATKAPAKDGVEADAGAMYAIITKSAADLEAVEATIAKFD
GVKVANYNAPTQSVIAGPTDSTGEAAKALSQLGYKAINLPVSGAFHTELVGHAQAPFAKA
IDAAKFTKACRALYSNATGTVYDTSATKIKASFKKHMLQSVRFTAQLEAMYDAGARVFVE
FGPKNILQKLVQGTLADKANEICTISINPNPKGDSDFQLKQAAVQLAVAGIKLDNIDPYQ
ADIAAPEKKSPMSISLNAANHISKATRAKMAKSLETGIVTSKVEHLIEEKIIEVEKVIEV
ERIVEKVVEVEKLVEVAVPAQAGVVQGSSIQASSVIDSGIESQVVSKNSKPAAHSVSGDA
LSNFFAAQQQAAQLHQQFLEIPQQYGETFTTLMTEQTKLAGSGIAIPESLQRSMEQFHQL
QAQTLQSHTQFLEMQTGSNIAALNLLNGSPATYAPVIENKVIQTEVVQREVVAQPAIIAT
PATPVQPAPVQTTAVQTAPTQAPQVKTAPVATTPQVQAPQVVRQAAPAQAAVVPTNTSPV
AVISAETALSATLSSEKVQATMLEVVAEKTGYPTEMLELEMDMEADLGIDSIKRVEILGT
VQDELPGLPELSPEDLAECRTLGEIVNYMNSKLTNTSAAAALNVSAAEGSAVSSTPVHSG
LSAETALSAQKVQATMMSVVAEKTGYPTEMLELEMDMEADLGIDSIKRVEILGTVQDELP
GLPELNPEDLAECRTLGEIVAYMGSKLPAEGSANTSAAAALNVSAAEGSLSATQVQSTMM
SVVSEKTGYPTEMLELSMDMEADLGIDSIKRVEILGTVQDELPGLPELNPEDLAECRTLG
EIVAYMNSKLTNTSAAAAQVPQVNAAPTTNGLSAETALSATLSSEKVQSTMMSVVAEKTG
YPTEMLELSMDMEADLGIDSIKRVEILGTVQDELPGLPELNPEDLAECRTLGEIVAYMGS
KLPAEGSMNSQHSSTVVSTTETPVNGLSAAKVQSTMMSVVAEKTGYPTEMLELSMDMEAD
LGIDSIKRVEILGTVQDELPGLPELNPEDLAECRTLGEIVSYMNSKLSTAGATVASTVAA
ATDAVKSVADTIASTLELPPHSEVALKKLNAADKLQDCFAADTTIVINDDGHNAGVLAEK
LTKQGLKVAVVRLPDGQPQSPLSSDVASFQATSIDETGITAIINQVEQQLGQIGGFIHLQ
PEANESNQADAVNLNEQGFTHLSQAFLWAKLLQPKLTASSDKRRSFITVSRIDGGFGYLN
IDALKDAELNQAALAGLTKTLSHEWPSVFCRALDIAVDVDATHFADAIASELFDANNQLA
EVGIAADKQGNVSRVTLVAGEASEKHSASALNSSDKILVTGGAKGVTFECALALAKRTQS
HFILAGRSELLAIPAWAENKQISELKPAAIAHIISTGSKPTPKQVETLVWTVKSSIEINT
ALEAFNQVGASAEYVSMDVTDTAAITAALNGRSNEITGLIHGAGVLADKHIQDKTIEELA
RVYGTKVNGLKALLAALDSSKVKLLAMFSSAAGFYGNTGQSDYAMSNDILNKAALQFSAR
NPQAKVMSFNWGPWDGGMVTDALKKMFTDRGVYVIPLKAGAELFATQLLGETGVQLLIGT
SMQGGDSTKADGSSQAEGSKEAASVKKLNAGEVFNTSRPLAPVALTPMTLTRALNPNAMV
FIQDHRISGNPVLPTVCAIQWMREAASKMLGAQVKVLDYKLLKGIIFDSKDAQEITLELT
PTDNGQMSALISSQGRPQYKATLAVSSERFTTKSFDLMGDAVTSASELYSNGTLFHGPRL
QGIKQVFNFDDAGLLAHCELPQVDSSDCGEFVATTHIGGSQPFAEDLLLQAMLVWARLKY
GAASLPSSIGEFISNKPLAFGDKAILELEVVKTNARSLEANVTLYHENGELSAMMKGAKV
TISKNLNSAFLNETALSVGESALSDSKKALSAEEKALSKGERA
>A0A5B7V2T4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MSNEEKLRDYLKRTTSDLRQARRRLREVEERDQEPIAIVAMSCRYPGGVRTPEELWRLVA
QGTDALTPFPTNRGWDADALYDPDPDNSGTSYAREGGFLHEADEFDASFFGISPREALAT
DPQQRLLLETSWEVFERAGIDPASLRGSRTGVFAGVMYHDYASRLHSVPEDVEGYLGTGA
SSSIVSGRVAYTFGLEGPAVTIDTACSSSLVALHLAVQALRQGECSLALAGGVTVMFTPG
TFVDFSKQRGLALDGRCKPYAEAADGTGWGEGVGLLLLERLSDARRNGHEVLAVVRGSAV
NQDGASNGLTAPNGPSQQRVILQALANAHLAPEQIDAVEGHGTGTTLGDPIEAQALLATY
GQERPEGLPLWLGSIKSNIGHTQAAAGVAGIMKMVMAMREGVLPQTLHVDRPSTHVDWSA
GAVELLTEPRTWDAREDGVPRRAGVSSFGVSGTNAHVIVEQAPVEEPAEVVEPVAPVTAV
PWLVSARSAEALREQAERLREHVAGDPGQDPVEVGWSLLSGRALHEHRAVVLGRTREDFL
TGLESLATGGPAAVTGAVAEGRLGVVFTGQGSQRIGMGKELYETFPVFAAALDEVCAHID
PWIERSLQSVMFGTDAELLEQTGYAQPALFAVEVALFRLAESFGVRPEIVGGHSIGELAA
AYVAGLWSLEDAAQLVAARGRLMQALPEGGAMLAVQATETDVLPLLDGLADRVGVAAVNG
PAQLVLSGDRAALEGLEQTLREQGRKVKWLKVSHAFHSPLMDPALDDFREVAAKLTYQEP
TLPVVSNLTGELAEPAELKDPEYWVRHIREAVRFHDGLNALTGFGVGTLLELGPDSVLTA
MAHDTLTEPESQSGLIAATRKDRPEADAFLTALAQLHVRGIAVDWAPLYAPVESRRRVAL
PTYAFQRQSYWLHAPALTGDVTSAGLAAADHPLLGAAVEVAGSEARLFTSLLSADAHPWL
GDHVVAGRTLLPGTAFVELAVRAGDEVGCDLLDELILEAPLVLPEDGGVQLQLWVEEPDE
SGRRTFTLHSRRQNDVPDEPWVRHAAGVLAVGEAGRPARQDADLAQWPPAGATAVDTGEL
YAGFATAGLGYGPVFQGVRAAWRRGHEVFAEVALPEGERDEAGAYGLHPALLDASLHGLA
FSAVGADGAGARLPFSWTGVSLYASGAATLRVRLTPAESGAVTLLAADETGLPVAAVDSL
VLRALAAGELDAASADDDSLFRVDWSVVSAPAVTAGAAYAVLGADELGLRSALEGAGATV
AAYADVAALAEAVEDGAALPESVFVTCVGGEHAGGTAAAVRTSLHEALTVAGEWLSFDGG
EDSRLVVVTSGAVGVGAGDVVSAEGLVDAPVWGLLRSAQSENPGRVVLADVDGTEAALAL
LPGALDLDEPQVAVRGDVVWAPRLTRAATGVATLAAPAGRSWQLGVTDRGTLENLALLPV
AEDAPEWAGRPLGAGEVRVEVRAAGVNFRDALIALGMYPGDAVMGTEGAGVVVEVGPEVS
GLAVGDHVLGLIDGGFGPLAVADERMVARIPEGWSFAQAASVPTVFLTAYYALRDLADLQ
AGQSLLVHAAAGGVGMAAVQLARHFGAEVYGTASAGKWDVLRGLGVEDSRIASSRTLDFE
AAVLAASDGRGVDVVLNSLAREFVDASLRLLPRGGRFVEMGKTDLRDPEAVAAAHPGVAY
QSFDLAEMSPDRIQEMLTEVLGLFEQGVLKPLPVRAWDVRRAPEAFRYLSQARHVGKVVL
TLPPVLRAEGTVLVTGALGGLGRVVARHLAGEHGVRDLLLVSRRGEEAPGAGEVRAELEE
LGARVRIAACDVADREALAGLLEGVRAELSAVVHVAGVVDDGILTSLTPERLDTVLRPKV
DAAVNLHELTAGLDLSAFVLFSSAAGVLGSAGQANYAAANAFLDALAQHRRAQGLPATSL
AWGLWADQGGMAGALADDDLERMSRAGVAALSAEEGLALLDDSLARADAALVPMKLRTDV
LRRQFGGDVPPLFRGLIRGGARTRRVVEAGPAAAGTSLADQLAALPPENRERALLDLVRT
QVAAVLGYASGEDVAPTKAFKELGFDSLTSVELRNRLNGATALRLPASLVFDYPTPKVLA
QYLGGELLGGLGESAAAGATAPVTVAAAQDEPIAIVAMSCRFPGGVGSPEDLWRLLTDGA
EAISEFPEGRGWDTASLYDPDPDQVGTTYAREGGFLHDAGNFDAAFFGISPREALAMDPQ
QRLLLEASWEAFERAGIDPATLHGSPTGVFAGLIYHEYGSQLSSVPEDLGGYLGTGSSGA
IASGRISYSFGLEGPAVTVDTACSSSLVALHLAAQALRQGECTMALAGGVTVMPTAGTFL
EFSRQRGLAPDGRCKPFAAAADGTSWGEGVGMLVLERLSDARRNGHPVLAVVRGSAVNQD
GASNGLTAPNGPSQQRVITQALANARLTTADVDAVEAHGTGTPLGDPIEAQALIATYGKQ
RPAERPLLLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGVLPQTLNFDAPTPEVDWSAGTV
ELLAEARAWPDRDGAPRRAGVSSFGVSGTNAHVIIEAPEQPERPAAAEAPAPSVVSGVIP
LALSGKTPEALRAQAGRLREHLVAHTGLAPADVAWSLTAARSRFEHRGVVLGRDRDALLA
ALEGLERDDAAAQGVVVGRAQGDTVRPVFVFPGQGSQWAGMARELLDESPVFAERMRECA
DVLAEFVDWNLLEELDGQHFDRVDVVQPVLFAVMVSLAAVWQAAGVKPAAVVGHSQGEIA
AACVAGALSLRDAARVVALRSLAIRELSGKGGMVSVPLPEAEVRELLTAWGDRVSVAAVN
GPAQVVVSGEPEALEELVAQCVARDVRARTIPVDYASHSAYVEEIEAQILEALEGVSPQE
AQVPLYSTLTGAWLDVPMDGGYWYRNLRQTVLFEHATRGLLAEGHGLFLEMSPHPVLTVP
VQATIEAAGREGAAVALGSLRRDEGGADRLMASVGEAYAQGADLDWRALVPGTLVDLPTY
AFQHQHYWLVSPEAEPGAEPAAAVDEVEARFWEAVEREDLEQLAAELEVTDGSAAELGAV
LPVLSSWRRQRRERSTIDSWRYAVHWKPLAGSLPGPVLTGRWLVVVPEEAAAHPWTAGAL
EALAQAGAETVELHVTGAELTREVLAGRLRGDVADAAGLAGVVSLLALAEEPHPAHPVLP
AGLAGTVALVQALGDEGVEARLWALSSGAVATGRGDRVESPAQAQTWGLGRVVALEHPDR
WGGLVDLPPTPDSRTGARLAGILAGVGDEDQLAVRGSGVLVRRLVRAEPAAPARETGPGW
TPRGTVLVTGGTGALGPHIARWLAREGAEHLVLTSRRGPDAPGAAELRAELEEMGVQVTI
ASCDVADRDAVAALLGRLAADGHTLRAVIHAAALIELAPIATTTLDGFADIVAAKVAGAV
VLDELLDGEAAAELDAFVLFSSIAGVWGSGDHAAYAAANAHLDALAEHRRARGLTATSIA
WGVWNVVNPHLSGSAPVDVDPEQLRRQGLPFLDPGLAFAGMRQILDDDETFLALADVDWD
QFVPVFTSRRARPLLADLPDAQRVLAAQGGAGDDAADAGTSTKASALRERLTGLAGPERD
RVLVDLVLTHAAAVLGYESAGALDPERAFREFGFDSLTAVDLRNRLGAATGLKLPTTVVF
DHPNGTALAAYLRTQVLGADAAAAPAAVAPVAAATDEPIAIVAMSCRYPGGISSPEQMWQ
VLQDRTDVVGGYPAGRGWDTAHLYDPDPETPGTTTTRGGGFLHDAGAFDPAFFGISPREA
LAMDPQQRLLLETSWEAFERAGIDPKAVRGETAGVFVGTNYQDYGTAPGQVSAGAEGHIL
TGSAPSVISGRIAYTFGLEGPAVTVDTACSSSLVAMHLAAQALRQGECSLALAGGVAVMS
SPGALIAFSQQRGLADDGRCKAFAAAADGMGMAEGVGLVLLERLSDARRNGHKVLAVVRG
SAINQDGASNGLTAPNGPAQQRVIRAALANARLTAADVDAVEAHGTGTTLGDPIEAQALL
ATYGQERPEGGQPLWLGSIKSNIGHSQAASGVAGVMKMVLAMQHGVLPQTLHIDEPTPEV
DWTEGAVELLTEARDWPERADAPRRAGVSSFGMSGTNAHVILEQPPLADEPAAADEPGVP
APVVAGVLPLALSAKGEPALRAQAARLREHLLARPDLAPADVAWSLAAARSRFEHRGVVL
GRDREELLAALERLAQDEVTPQVVSGRTLGGMVRPVFVFPGQGSQWAGMAVDLLESSPVF
AERMRECAEALAEFVDWDLLEELSGEHFDRVDVVQPVLFAVMVSLAAVWQAAGVKPAAVV
GHSQGEIAAACVAGALSLRDAARVVALRSLAIRELSGKGGMVSVPLPESEVRELIAGWEG
RIEVAAVNGPAQVVVSGEPEALEELVAHCTGQDIRARTIPVDYASHSSYVEEIEAQILEA
LEGVSPQAAEVPLFSTLTGAWLDVPMDGGYWYRNLRQTVLFEHATRGLLAEGHGLFLEMS
PHPVLTVPVQATIDATDSQAATLGSLRRDEGGEARLMASLAEAHTYGAELDWKALFPGTR
ATVELPTYAFQREHYWLLAPQEELSDAAPQATDEVESRFWDAVEREDLEQLAVELAVEDS
SAADLGAVLPVLSSWRRQRRERSTVDSWRYQVDWQPLAGALPATGLTGRWLLLVPEGAEA
TEVVAALAQAGAHVDELRVTAGEMTRETLTARLFEHTLTADGEPSGVLSLLALDESALTD
HPGVSAGLAGTVALVQALGDAGIGARLWAVTRGAVATGRGDAPARPGQAQAWGLGRVAAL
EYPDRWGGLVDLPETVDARAAAQLAGILAGAGDEDQLAVRQAGVLVRRFVRAPLDAGAAR
EWAPRGTALITGGTGAIGGHVARWLAREGAEHLVLTSRRGPDAPGAEELQAELEELGAKV
TVAACDVADREAVAALLDRLTEDGHALRSVFHAAGVGQGQPLADMSAADIAAVLEAKVAG
AAHLDELLATATLDAFVLFSSNAGVWGSGSQGAYAAANAHLDALAEQRRARGLTATSVAW
GLWAGGGMAGDDGEEQFRRRGLRPMAPDLAVAALAQAVAHDETFLAVADLDWERFAPAFT
SARTSPFIGDIPEVRRYERSVAAETATEADTGDDAAAELRRRLTPLTEPEREMILLDLVR
THAAAVLGYGDAESIDAHLAFRELGFDSLTAVEVRNRLNKATGLRLPATLVFDHPTSAVL
SQYLRGELLQDDADGVDSTLRELDRLEAGLGTIAPDDGDRMRITMRLEALMAKWKGTDAE
APADGEKVSSQLESASADEVFDFIDKEFGVS
>A0A5B7UM07|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MSTDDQVVAALRASLLDNQRLRQENRGLADASREPVAVVAMSCRYPGGVGSPEDLWELLV
KERDAVTAFPADRGWDLDGVYDDDPDAPGTSYTREGGFLHDACAFDPGFFGISPREALAM
DPQQRLLLETSWEAVERAGIDPRSLKGSRTGVYAGVIYSEYGSRLDRVPDDLEAFLGTGS
IASVASGRVAYTLGLEGPAVTLDTACSSSLVAIHLACQALRSGDATLALAGGVTVMATPG
LYVGFSRQRGLAPDGRSKSFAAAADGAGFGEGAGMVLLERLSDARRHGHPVLAVVRGSAV
NQDGASNGMTAPNGPAQERVIRQALDSAGLAPAEVDAVEAHGTGTVLGDPIEAQALLATY
GQDRPAGRPLWVGSLKSNLSHTQAAAGVGGVIKTVLALRHGLLPRTLHVDRPTPQVDWTE
GAVSLLTAATPWPATDRPRRAGVSSFGASGTNAHLVLEQAPEEPAPEEPAEEHGEPAAPT
GPVAWPLSAKGPAALRGQAAALHAHVLADPALRPADIGLSLATGRSRFADRAVVVGADRG
ALLDGLGALARGEPLTHGVTGTAPRGGRKAVFVFPGLGAQWPGMAAELLDASPVFAARVA
ECEQAFAPHLDWSLGGVLRGEDDAPFLDGVEVLQPALFAVMVSLAEVWRSYGVEPAAAVG
HSQGEVAAACVAGALTLQDAARVIALRSRALSRVTGGGGMATLMMSGDEAEELLAARGGE
VSVAAVNGPRVVVVAGSAAAVRDLVADLTGQGLMAFHIPVDYASHSGAVDAVRDELHAAL
ADIAPRTPAIPLLSAVDADWLTAADLNPGYWFRNLREPVRFHPAVRRLLDEGHRTFVEVS
PHPTLTYGIADTAADADAADVEVIGTLRRDDGGPHRLLLALGEAHAAGLPVDWRPAYEGT
GARRVGLPTYAFQRQRYWLDAPAPSGDPASTGQSAAGHPLLGAAVDLPDGGTLYTGRLSV
AAHPWLADHAVAGAVLLPGVAFLEMAAHAGAPLGCAQVEELTLAAPLLLPDGDEAARGVH
LRLAVGPADTEGRRTLAFHSRAEDAAADEPWSQHAGGALAPAPAERAAPARTAWPPAGAT
PLDVDDLYEAMASRGVAYGPAFRGLRAAWGHGDDLYAEVTLPDGTPDTFAVAHPALLDAA
LQTTGLRTAAATGDAVPLPFSWSRVTLGPGTGRTLRVALRPDGDDAVTVRVTTEDGRTVA
DIGALTLRAASYDGLRVADRSLYRVDWSPVDRPAVPAPGAGARWALLAERDARLLPDDFA
GSDPAEADAVLLPCPPLAGAEGPEAVHTATADVLERLRARLADPAAASAPLVVLTRGAAG
PGAGPGAGAEPVDVPGAAVWGLLRAAQLEHPGRFVLLDTDDPAATAAALPAALAAEEPQL
ALRDGVLYAPRLARAAAAPDTASPAFDPNGTVLLTGGGGVLAGIIARHLVTRHGVRHLLL
LGRRGAEAPGTAELARELGESGAHVTVTACDVADRAALAQALDGIPTEHPLRAVVHTAGV
LDDGLLDAQTPRRLSAVLRPKADGARHLHDLTRAADLTAFVVYSSAAGVFGSPGQSTYSA
ANASLDALMTERHRLGLPATSLAWGLWEQRSALTAELSDTDLRRMRRSGVRGLSAEEGAA
LFDRALALAEPVLVPVHLDLAAYRDQAVPPLLRGLVKAAPAGPRPAADSAPLRQRLAAAE
PGEHGRILLGLVLAQAADVLGHATPEALGAEDAFLSVGFDSLTAVELRNRLAARTGLRLR
PTTVLDSGTPARLAERLRGELAQEAAPAAADGPAPGPATDPVGTLFRQACELGRVDEGIA
LLKNAAALRPDFRTGAELLAAPAKPELLRLCPHDGAPELVCFGSVVALGGAHQYARFAAR
FRGRYGVSALAAPGFLPGEPVPADLAALLDFQAGTLRAELGGRPLVLLGSSSGGTLAHGV
AARLEELGAGPAAVVLLDTYLSDNAGMTQFNDVLVGGMFAREERATPMDGTRLTAMGRYF
RLLDTWTPPAVRAPTLLVRACEPLGEPDPDAGDWRATWPTARSVVDVPGDHFSLMEEHVT
TTADAVSDWLAEVVDFPPRTTP
>B8MCS4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MPIYTPTTSSDPDVDSHKMKLVYFSNEFPREDLQDVFRRLHNHSRDKHHPILAQFIYEVT
WAIKEEIRQLPTELKQLIPPFESVFSWAENTELREGLICGAVDGVLLVVVQLATYIGYAE
NSPDELTDFANTSLAGLGIGLLASTAVSLSSTLADLPLAGADAVRLAFRLGIHVLGMSEN
LEARDLSETPDTWAYVVHNVDSDATQKELDTIHSREGVPNTGKIFISAVSRTSVTVSGPP
ARLKSLFNKSDFFRESKFIPLPVYGGLCHAPHIYGIQDTQSIVRRSSLNTVNRKAWPTTP
IYSTSTGLEYPAKTAAKLLEGVVSELLTQAIYWDRVISGVVEKVETAVATEAVLYSFGNS
IPLNDLNSALKSSITHPEITHNNLMTWVAQIPPRGSTPRGTAQSKLAIVGMSCRLPGGAT
NTEKFWEILEKGLDVSRRIPADRFDIDAHYDPTGKELNKTMTQYGCFIDEPGLFDAPFFN
MSPRESQIVDPQMRLALVTAYEALERAGYVGNRTAATQLQRIGTFYGQAADDYREVNQGQ
EVSTYYIPGGCRAFGPGRINYFFKFAGPSYSIDTACSSGLAAIEVACQALWNGEVDTAVT
GGVNVLTNPDGFAGLCNGHFLTKGHNACKTWDSTADGYCRADGVGSIVIKRLEDAEADND
SILGVILGVGTNHSAEAISITHPHAGHQAYLSRQVLRQAGVDPLDVSYVELHGTGTQAGD
HEEMQGILDVYAPLTRRRSKGQPLHIGAVKANVGHGESVAGTTALIKVLLMLQKNAIPRH
IGIKTEINPNFPRDFNKRNLHIPMEMTSWPQVPGKKRLAAVNNFGAAGGNTTMVLEEPPI
REITETDPRKVHIIATSAKVKTSLAGNIKRLIAHLDNHPDINLAELSYTTTARRYHHTHR
VAIATTDVDHLKKQLKSRLEKIDSIKPVGKSGMPPVAFSFTGQGASYKSMNLELYRDVPT
FREHIQYLDSLAQGQGFSSFIPALDGSYPQDHAHSAVITQLALVCTEIALAKYWSSLGVK
PDVVIGHSLGEYAAMHIAGVVSASDTIFMVGRRAQMLEQKCKIGSHSMMAVRASLTQIAE
SSEDKPFTVACINGPSDTVLSGTKEQVDDISVSLEAAGYRCIKLDVAFAFHSEQMDPILD
DFEAITTTGVLFQELKMPVISPLLGKVIFDSKTLNANYVRRATRQTVDYLSAIENARKVS
TISDETIWIEIGPHPVCTGFIKSTIPSTQLAIPSIRRGEDNWKTMAESMAALHLAGVEVG
WNEFHRPFERRLRLLDLPTYAWNDKNYWLQYNGNWCLTKGNTFYDNEKGADAAKTLPKAL
PASEIQTTTVQQIIEENFNGSAGTVIMQSDLMQADLLAAAHGHSMNKCGVVTSSIHADIA
YTLGNYLHRKLNPKAKNVNMSISNLVVTKGLVAQTNKKKPQLFRVTAATANIASGIVDLT
WQNVDNDGNVYQPFATANIYYGDATEWLSSWAPVAHLVLGRIDALEQLATQGKASRFSRN
MAYTLFASNLVTYAEKYRGMQSVVIHDLEGFANVQLTTKESGVWTVPPYFIDSLAHLAGF
IMNCSDAMDTQNNYCVTPGWNSMRFAKHLVPGAKYLSYVKMIPTAEDPTIYFGDVYILQD
DAIIGVVNGIQFRRYPRILLDRFFSPPDKITVSESNPKPTPSRTAVPVSASPKSAIPAPK
PTVAQPDLDTGNDDGKSKPSPSNTPTPMPAPTENLTPTVTDTAGPSIETTAASGSVTAKA
IMLIANEAGLDLSDMEDDASFAALGIDSLMSLVIAEKFKTELDIKVSGSLFLDYETIGDL
REWLDEYYN
>G0Q181|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MKQLLLDFLWSHLRTLGAFRASGQTPEAARESAGLAPGYGAWFDECLRVFEAAGRLERRD
GRILLDDTARGRPIEELWREWEREKPVWRENPDLAATHELVETTLRAFPDILSGRRPATE
VLFPGGSLDLVQNAYATNPASAYFNQVLAADLVARLRRRSPDRTADPARILEIGAGTGAT
SAVVLEALRSARIDVREYRYTDLSRAFLNHAEHAFGAENPWLTYGILDIERPVAEQGLTP
GAYDAVVAANVLHATRDIRHTLRNAKALLRPGGLLVLNELTANNLLSQFSFGLLDGWWRY
EDPHLRVQGSPLLSTAGWRHVLTREGFHAIALPAREAEDLGQQIIVAESDGVVRRATAAP
RPSPPQATPVRESPPRAAGHGAGGESGDRLPAHIEAVALDVLAEALDIPRTRIGRDEPFS
NYGLDSIFAVNVARTLGATLGLDLDITVLFEHNTLAELGGFIVSEYAEELRDVLPPEPAA
PDRTPGPVPPRPEPDGPALDGMAIVGMSARFPGADDVDAFWRNVEEGRRSITAPPQKRAD
WAVHGDGAADLRGGFLDGVHEFDPLFFRMSMTEARQVTPELRLLLMTAWNAVEDAGYRPA
ELRNRPTGVFVATTQSEYRPAATDLMSLPSPAMVPNRISYLLDLDGPSEQCDTTCSSSFV
ALHRAIRSIRDGECEQAIVGGVNLVMSPAGFGGMRAAGMLSPRGDVRPFQQGADGTARSE
GVAAVLIKPLRRALEDGDFVHCVVRGTGVAHGGRGVSFTAPNIRGMKTAVAHAYADAAID
PGAVEYIETHGMSSTLADSAELAALGAGFREDGSEDVTYLGNVKPCIGHTEVVSGLAALV
KTAQAMRHGVIPAIPGFEELHRDLSLKGTRLRVAERNLPWPGRTDDAGLPLPRRAALHSF
GIGGVNAHVVLERHTAPEHPEDDQGAQVLVLSARGADALRERARRLLHRLAGADPRSWAD
IAYTLQIGREAMSCRLAFVARSTDEAARLLGSWLDGDPDTLARVAFADGVEPAAGAGHAA
TPTQLDDLAEHWVAGTFTDWDQVHRGVRRRRIALPGYPFARLTCFAEQAPGPGTEHTPPD
GDPHTGVGPPDGEAFVADLVASVLGLERHEIDGTRSLADYGLNSLLLVAMLGRIGQVFPG
FRPEWWQPHDTLDAVVARLPEAAARSPRGPAPELVRLNGATAGRPVFWIHGALAGVESYR
TIAERVDRPFYGIQARGLLTEEAPIEGVTAMAEHYTEAIRSVQPEGPYDVGGFCLGGIIA
YEVTRLLQARGQEVASLTMVDSPDETGLAKSNANGFQSARSAALQVVNSLLWPAGEKDPA
VLRARLVHRDEVAEEDLDEDAFVLRLAELAAGRGLAMRPAQIARFTRRNMAIQLAYRLGE
HTIRPLPRPRAVVCTYFRNRRGLFLGEAEPYFQVAGETFSLDHVNYQQDWGREMPDLRLV
EIEAANHMTILNDAEPLAAIEETCLALYASDEIGASRG
>G0PRM6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MSDNQKLRDYLNKVTADLRQTRRRLEEARSADAQPIAIIGMSCRFPGGVESPEGLWELVA
GERDAISPFPRDRGWDVDGLYDPDPERTGTSYARAGGFLADAGGFDAEFFGISPREALAM
DPQQRLLLELAWEVFEAAGIDPTSVAGRPVGTYVGTSTSGYGITLAQAPPGVEGYLLTGS
AAAVASGRIAYALGLEGPAVTIDTACSSSLVAMHLAAQALRSGESELAVAGGATVMSSPG
TFVEFSRQRGLSPDGLCKPFAAAADGTGWGEGVGLLLLERLSDALTNGHRVLGVLRGSSV
NQDGASNGLTAPNGPSQQRVIRQALRNARVAGAQVDVVEAHGTGTTLGDPIEAQALLDTY
GQGRPEGRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGELPVTLHVDEPSPHVDWSA
GDVRLLTESVPWRADGHPRRAGVSSFGVSGTNAHVILEEPPAVRPKTAAPVADSGPVAWV
LSGRGDAGLRGQAARLADFVRDRRAARTVDREWLTGVAAGLAGRAALEQRATVVGSDVDE
LLKGLDALTADGQPLAAATDSRTVFVFPGQGGQWVGMGRELLFSWPVFADRLAVCERALD
PFVDWSLREVLTGSDEKWLGRVDVVQPVLWAVMVSLAEVWRAAGVEPDAVVGHSQGEIAA
AVVAGRLSVEDGARVVALRSRALLRLAGQGAMASVALDVADVEGMLPASVTVAAVNAPGQ
VVVSGPPDEIAELCVRLDGQGVRARRIEVDYASHHAQVEVVEGRLLGELGGVVDLGGSGP
EFVSTVTGGPVAVGELGAGYWYRNLREPVLFADVVRRLDGEGPQVFVEIGPHPVLSLAME
QTVTEGRVLHSLRRGQPEKVQMLSSLGEAWAAGLPVGWRELLPVVEPVALPTYAFQRQHY
WLTPPASTRQTAVGRYRIGWRTLPEPEPAGEPRTSDWLLVHEEGHRADEAAALAAALTAE
GGSARVVTVPAGTDGIDGPPGAAGTVEPDLLTRLLGDAAPSDEQAPGVVSLLAGEAAVSL
LRAVASLPGQPRLWQLTSGAVGVSDADTVADCAQAELWGWSRCFALEHPDRWGGLIDLPV
GVAADDMVARTAARLARGGDEDQIAVRPEGSYGRRLLTVTDQPGDPRTEWPSAGTVVVTG
GTGGPGRHVARWAASRGADRLVLVGAASAELCAELTEAGTPTVTVAGDITDPEALRLLLR
EATADVPLAAVVHAAGAIELAPVRQSDPAHAARVMRERCTGAETLAEVLRTDHPDARLVL
LSSVAGVWGAGAHGAYAAAGAHLDALAERERAAGRPVTSVAVSPWEAEPELADLLRGQGV
PATDSGAALAALPGLLALPEAAVVLAHVHWERFVPTFTAAGPRPLIGDLPEARRVLDAEA
EAQGAPDPDAAHTSKLARALAVSSAAEHDRIVLAEVRATAAAVLGYAGPDAIGEAKAFRE
LGMDSVTAVELRNRLSAASGVRLPATLIFDHPNPTAVARLLRRELTPGLVEADDARSETP
PRPAAEDEPIAIVGMSCRFPGRVASPEDLWQVVAGGVDAVAPFPDDRGWDMSALYDEDPD
RARTVYARGGGFLHDVAGFDAGFFEISPREATAMDPQQRLLLETSWEAFEQAGLLPEDLR
GSDTGVFVGTNGQDYASLLMSGDDGLEGYLGTGNAASVASGRVAYTFGLEGPAVSVDTAC
SSSLVAMHWGAQALRQGECSMALTGGVTVMTTPGSLLTFARQRGLATDGRSKAFSAHADG
MGMAEGVGMLLLERLSDARRNGHRVLAVIRGSAINQDGASNGLTAPNGPAQQRVIRQALR
NAGLEAADVDAVEAHGTGTTLGDPIEAQALQAAYGQDRPAGLPLWLGSLKSNIGHTQAAA
GVAGVIKMVMALDRETLPRTLHADEPSPHVDWSGGALRLLTDPLPWQRSERPRRAGVSSF
GMSGTNAHVILEEAPAAGTQDTAEPGAGNQEAPVVPPWLLSAKSEAGLREQADRLRRRLR
AEPGTDPVDVGHALATTRSSFAHRAAVRGAGPDELLAGLAAVAAGEQSPYVLRGRADAGE
RPVFVFPGQGSQWDGMAARLLDTSRVFRDSVEACAEALAPHLDWSLPDVLRGSAGAPPLD
RVDVVQPALFAMMVSLAELWQAHGVRPAAVVGHSQGEIAAAYVAGALDLDDAARVVALRS
RMLAGLQDSGGMTSVAAPVSWVAERLPRWGGEVEIAAVNGPRSVVVSGPVRGLELMEKEC
AAEEIRVRRVPVRYASHSRYVEELRTPLLAALDGLSPRAATVPFLSTVTGGSVDTATLGA
DYWYRNLRHTVRLDEAVGDLLGRGHRAFAEMSPHPVLTAGLLDTAEQAGTDAFAVGTLRR
DEGGLDRFLTSLGEAHVRGVRVDWRPAFTGHRPCPVELPTYAFQRERYWVHAAPPGAGDV
AAAGVEPADHPLLGAEIVLADTDELVLTGTVRTPALPWLTDHQVSGVTLLPGTAFVDLAL
RAGERCGCPVVEELTLQAPLVLPEGGEPRLQVRVGPADDAGRREFRVHSRTENGAGSAIA
LAGGADDAGWTCHATGSLLADADADAGTDAADAAASAVSPGVEAEPVAAAEPAAWPPAGA
TAVDITDGYDRLAELGYGYGPAFRGVRAVWRLGDEVFAEVRLPERLTQEAGRFGLHPALL
DAGVQAVGLAATGAGGEEPDGGGDATAVRLPFAWTGLNLHRAGANALRVRLAPTANGGVS
VRATDETGAPVLSARALEFRPVSTRGLRLSGGSLFRLDWRETPALRAPATPEAGGWAVVG
PDADELRTLLDAGGADATAYADLPALLDATASGAPAPGTVLLAPEPAWSGSTGFVDEVHT
RTASRLALLQDWLGEPRWADTRLVVTTRGADALDPVAAAAGGLVRSAQAEHPGRFTLLDL
DGDVRPRAVVDAVASGAPHLVVRAGTVLEPSLVRLPAPTGAPAPLTGTVLVTGGTGTLGA
QVARHLAAEHGVKHLLLISRSGATAPGAPELRADLAALGCEATIAACDSADRDALRTVLD
ALPADRPLSAVIHAAGVLDDAVLTSMTPGQLERVLRSKADGAIHLHELTRERPPAAFVLF
SSAAAVLGSPGQGNYAAANALLDGLARHRHAAGLPALSIAWGLWEQRTGMTGHLSPADLR
RMTRAGLAPLDTEGGLALLDAALAAGEATVIGARVDLATLRARDAGATIPPLLSGLVGAS
ARTAPNGSAEREPETTVRRELQGRTPRERRQVLLRLVRSATAVVLGHTDAGQIPSDGAFT
ELGFDSLTAVELRNRVQSSTELRLPATLVFDHATPLALAAYLDGELADGPGPAPAEAPRA
PVEHAAPDTVEALYREACRQGKGHVAMDLIAAASRLREQFSDPAALAAPPRPVRLASGAD
GPVLICLSTITALSSVYQYARFGTALNGRREAWFVPVPGFTAEEPVPADVDAVVELHADL
ALRCAEGRPFALVGHSAGGWLAHAVTSRLEDRGVPPVGTVLIDTYLPGSSAFTQVQDALT
DLMFDHESTVGRLDSVRLTAMGAYLRLFDDWSPEPVHTPTLFVRAGEPVTDTVRGDGWRL
SWPLPNTTREVPGDHFSLMQSGAATTAEAVDAWLRELPGPKTG
>B2ILM7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Beijerinckia indica subsp. indica (strain ATCC 9039 / DSM 1715 / NCIMB 8712)|TrEMBL
METIVAITPWHTIDPQIAIAASKAGELGILDLGLQDDAAAITAALHQLRSMTGAVGRWGV
RWDTFGADSRGLDQLANNLQGEIPVLVLAGLKTHEVLKQLKAAERLAQQVFLEVHDQDTA
LAAQAAGYAGLIVKGHEAGGQVGKSSSFILLQELRGPIKIPYWIQGGISMHSAAAAVLAG
ATGVVLAEQLWLTQEGPCFSPGQRELWSRLDGSETLTIGRDADLFRLSNRHGRGKLRELE
LAVAKGAGWQELLQRQLSDHIDPLMPVGQDIAFAGAFGQRYVTVGSVIMAMRNAIDASLS
QAGSNNHLAPDSPLAKLHGTRYPIVQGPMTRVSDVAPFAKAVAEAGGLPFLALAVMRGPQ
ARALLVKAKELMGQRSWGVGILGFMPLDLRQEQMEAVREVKPPFAIIAGGRPSQARELED
LNISTYLHVPSPGLLKEFLKEGARKFIFEGSECGGHTGPRTSFTLWGSAIDTLLNAEIKD
PESVQVLFAGGIHNAMSAAMVSVMAAPLSERRMKIGVLMGTAYLFTQEAVHAGAIVQEFQ
EQAIACEETAVLQSGVGIYTRCAKTNFCNEFDDKRNELLLDTKSDDQILMELELLNIGRL
RIASKGVSRNANSTASDGTDRYTGLDVETQRREGLYMMGEVARLRKARVSMAELHNDVSA
EATAVLAQAALRQAEHKHPAMPKPHEDIAIVGMASLLPGASDLPSYWQNIMLAVNAIREV
PESRWRADDFFDPKRGIKDKVYSRWGGFLDDVAFDPTHYGIPPASLRSIEPIQLLALHIA
SKALEDAGFDRRPFPRERTATIFAASGMNDLGMDYIFRTLLTHYLPKVEGVSEDNRKRIL
DSLCEHDLPKWTEDSFPGMLANVVSGRVANRLDLRGTNFTVDAACAASLAALDTGIRQLR
SGDADVALVGSVDGANNVLGFMTFAQTHALSPRGRCRPFDDSADGIALGEGVAAVVLKRL
TDAERDGDKIYAVIKGIGSSSDGHNRSLTAPHPQGQVRAIERAYADAGVDPASVTLIEAH
GTGTALGDRSEIESLNLAFGTASTQHQYCAVGSVKSMIGHTKVTAGLAALIKASLALKHR
VLPPTLGVERPSSRVDFPNTPFYINTEARPWLGMPEGQPRRCGVSAFGFGGTNFHTVLEE
YRGEYRPSDSQDLNPRAAEIFAFGRAKRPEVEQAVRTLLQGLAQPEHLNLAQLAYAVHLD
EARVRPKNGALTCQLAIVASSVADLKTKLEFFLRESKDKTSIKAPQGIYYREQEHREDSG
AVCMLFSGQGSQRINMLRDLVLTRPASYALFERADALLKEALPQPLSRYIYPLPSFTKEE
QEQQQKALNDTHVAQPALGVIDLTALDFLTSFGLRPNFVAGHSYGEYVALCAAGVISRDD
LIRLSEVRGRIAAQTSKAESGTMAAVNADEARVVEAINRLGLAVSVANLNAPDQTIIAGS
AEAIDAAVKALIQESLRIKPIAVTAAFHCAAMAEAQEALAAELAKITFQRPQISLFSNTT
GNRYPDDPGEIQALLARHIAEPLRFVDEIQHLYEAGARVFIEAGPGLVLSGLVDRILGDR
PHVSLGIDVPDRPGWLQFAHLLAQVFSLGLPINLEPWFQRRGLADTNLEQTLAQARAKAQ
PGPMVWRVNGGKAVPWYTPIQAPSQASTKIPTPPKTPSLSAPSIHKPINTQAAQDGALPN
GLARPAINPAAAERASGSTAAPASQNSFVEREGRPVVSNYDPSSRIAASPPAAYALGSES
RFTEVQGSLAQLIDLQRTQQETLRRFFEFQEHWLTGQRPEMTAPSNSVLALANVQPLPAQ
LPPVPARAPAATIVPPAPVLPKFAVAPSPHGAKPTQPAPAAFASPTLNAVPARAPAMSGN
GSAKAKNTTDAKAFAPTEQFKADLLRAASERTGYSEDMLDLDAHMEADLGIDSIKRIEIF
SKLKDQYPFMEGRAEETVFEELSSLKTLNAVINWYDGLRQTLAKPGGGADPIKIPPLAAS
VSLLETAAPQNSGVGTNGSAADHVILKAKSTTDAHATGEKAFAPTEQFKADLLHAAAERT
GYSEDMLDLDAHMEADLGIDSIKRIEIFSKLKDQYPFMEGRAEETVFEELSSLKTLNAVI
DWYDGLHQSMAMPEGADSVKKSQTPSSVSLPEAAESIEIMASADEVQRYTVTPVAAPRDG
MAEMNGFPADRLILLVGDVPILGTAFRDRLTAKHYHVRQIVSGTDTHVLDEDRIEVDFSS
LDGVSKLRALIAEKGQKVGALFNLAGLGTIADAANDQHLEYARRLFLLLKVLETDLKESA
PIGGGWLINLTAFDGQFGLRQTRAFPALHAGTLGVAKSVAREWPGIRVKCIDVDPDIDLH
HLVTEVLREVGNDDQTVEVGFTPKERWKLDLGKGSATAADLSTLDLDSNSVLLVTGGAYG
ITADVTQALAEKFHPRLVLVGRSPMPEEEAKATRDLVEPQQLQQYLIHELRAQNPKTTPA
EVNRALKRMLRDRQIRANLAAMRAAGAEVDYHTLDIRDGEAFGRLIDDVYARWGRIDGVL
HGAGVIDDKSIRDKSPESFDIVFTTKVVPATVLANKLRPEGLKFLMFFSSIAGRFGNAGQ
SDYSAANEVVNKLADRLSHDWPHVHTIAINWGPWDGGMVSDELRRLYATKNIHPIPVAEG
RQRCLEELGRSNSGKPEIVVAASLQQIAQLALRQ
>A0A0N1H250|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OV450|TrEMBL
MANDEKILDYLKKVTADLHQTRQRLQDVEAQAREPIAIVAMSCRYPGGITTPEELWQLVA
EGRDAVAGMPTDRGWDLETLMDPNPDAPGASYVHQGGFLENAGMFDPGFFGLSPLEAEGT
DPQQRLVLEVSWEAFERAGIDPETLRGSQVGVYMGSGIQDYGDYDEGVPEAVEAFMATSR
ASSVISGRVSYTLGLEGPAFTVDTACSSSLVAIHLAAQALRQNECRLALAGGVMIMSTAS
PFVAFSKQKGLSPDGRCKAFSDSADGTGWAEGAAVILLERLSDARRNGHEVLAVIQGSAI
NQDGASNGLTAPNGPAQQKVIRQALANAEIPGAHVDLVEAHGTGTTLGDPIEAQALLATY
GQDHTAQRPLRLGSFKSNIGHAQGAAGVGGVIKTVMAMRNGLMPRTLHVSEPSSHVDWSA
GHVELLTEALPWPKAEDHARTAGVSAFGLSGTNAHVILQEAPEPEPAAADAEPVRHAPAV
TSPVLPYVVSARGAQALRGQAAKLAAFVRERAGDEDPSGIGHALITRRTAFDHRAVVLGE
DREALLAGLDTLADGGKAPNLVRGTASGSPQVAFVFPGQGSQWIGMAVELLDSSPVFAAR
MGECAEALAQFTDWNLIDVVRGEPGAPTYDEVDVVQPVLWAVMVSLAGLWRSFGVEPAAV
VGHSQGEIAAATVAGALSLEDGARVVALRSKIIRTGLAGRGGMMSVRLPSAEVRELIARW
DGRLQLAVVNSPTSVVVCGHPENLDELYAHLEAEGVQARKIPVDYASHSVFVEEIRDEVR
AALSGVTPRSADVSFYSTVVGAPVDTATLDADYWYRNLRQTVLFEETTRALLDDGFTVFV
EASPHPGLLVGLAETVSAVGVGAAPVGSLRRGEGGMQRFATSLAEAWAAGAPVDWTLFHG
SAPARPVDLPTYAFQREHYWAPAPAGTGDVEAAGLDPAGHPLLGAVITAPDSDGFTLTGR
LATATHGWLGDHRVGEQVFFPGTGFVELAVLAGDRAGCTTVEELTLEAPLVLPARGGVAV
RVTVDAPDPAGRRAVSVHSRGEDTGLSWTRHAVGTLGSAAAPARPFDTTVWPPAGAEPVD
LDGFYENVAAEGLNYGPVFRGLTAAWRLGEDLYAEASLPDGTDGSPYGLHPALLDAALHT
VALTGVTGDRAALPFAWSGVTLAAEGASAVRVRVGALGDGEVAVDLADASGQPVASVDSL
VLRPLTDNRLAQDRSLTRDALFRIDWQALPAAAADATSATWEATRSAAGDTGPADLVLWD
VPAGNGAEAARTAAHEALAVVREWLADERYAASVLVVRTRGAVAARAGEDVTDLAGATVW
GLVRSAQSENPGRVVLADAATDADVLTAYAAGESQIAVRDGVAYAPRLVRAAAPAASDDA
GDDGAAPRFAADGTVLLTGGTGMLGRLFARHLVTAHGVRRLLLAGRRGPDAEGAAELAAE
LTELGAHVDIAACDAADRDALAALLATVPAAHPLTGVVHLAGVLDDGVLGSLTPERIDAV
LRPKVDAALNLHELTADADLSAFVLFSSVAGVFGNPGQANYAAANAFLDGLAAHRQARGL
PAQSLAWGFWGEASAMTGSLTDAERSRISQGGVFPISADEGVALFDAAGRAGDATLVPVK
LDLGAIRAQGASAREVFRSLAPVTARRKAGGKVEAGALQQRLAALPAADREEVLVELVLR
QVADVLGFSSTQAIEPERAFKELGFDSLRAVEFRNGLAEATGLRLPATIVFDYPNPLGLA
RHLLTEVSGLPEAAAARPAAARRAAAATADDDLVAIVGMACRYPGGITSPAGLWRAVADG
VDAISDFPADRGWDLARIYDPTGARPDTSYVAQGGFLYDAGDFDPDFFGISPNEALIMDP
QQRLLLEASWEAFEDAGIDPRTLKGSSTGVYSGMMYHDYAHNASTGGIASGRVSYVLGVE
GPSMTVDTACSSSLVSLHLAIQALRSGECTLALAGGVTVMSDPEVFVEFSRQKGMARDGR
CKSFAGAADGAAWSEGVGVLVVERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPS
QQRVIRAALDSAGLTTADVDVVEAHGTGTTLGDPIEAQAVLATYGQDRDEDKPLWLGSLK
SNIGHAQAAAGVGGVIKMVQALRHGLMPKTLHVDEPTPVVDWDAGNVRLLQEPVEWPATA
GRPRRAGISSFGLSGTNAHVILEEAPADATAPAGEHRELPLVPVVLSARSPQALAEQAQR
LLARVGEDTGLSLTDLGHAAATSRTPHDHRAAVIAGNRGELLAGLAALAEGSATAGVVQG
TVRDGKPAFLFTGQGAQRPGMGRELHAAFPVFAAALDEVVAALDTYLDTPLYQVMWGESA
EDEALLNSTAYTQPALFAVETALFRLVESWGVRPSFLAGHSIGEITAAHAAGVLSLQDAA
RLVAARGRLMQALPAGGAMAAVEATEEEVLPHLTDTAGIAAVNSPRSLVVSGAEEAVEEI
TAVFTALGRKTTRLRVSHAFHSPLMDPVLAEFHLVAENVTYHPPKIPVVSGVHGEISEDW
GTPEYWTRHLREAVRFADTVRYLHGQGVTRFVELGPDAILSALTGTTLDGQDVSVEPVLR
GNRPEPQTLLTALARLHTTGTRIDWQAFYAGTGARRVDLPTYAFQRRRFWILDGQAAGDA
TSLGLSTVDHPLLGAVISAPETDGIVLTGRLALSAQPWLADHKVGETVLFPGTGFVELAV
QAGDRIGCPAVDELTLEAPLVLPPHGGVAVRVAVGAPDESGRRPVTFHSRGEDEDLPWVR
HAVGTLAEEPAEPTRPFDATAWPPAGAEPVDLDGFYADVAEAGLAYGPVFQGMKAAWRSG
DDVYAEVALPDGVEPDGYGVHPALLDAALHPVALSGVTGGEAALPFALSGVSLSADGAAS
LRVRVSARGEGSVAVDLADASGVPVASLASLMLRPLAAEQPAADGRSVVRDALFRIDWPK
QPSAAAADTPVQAWQSLGDGPVADTVVWDAPAGSDAAAVHTAVGGALEVLREWLAGERFE
GSTLVVRTRGAVAVADEHVGNLAGAAVWGLVKTAQSENPGRVLLLDTDTADPADTADVAL
AVASGEPQAAVRAGAVHAPRLVRAAADADTATTPAAEFAPGGTVLITGGTGMLGRLFARH
LITERGVSRLLLTSRRGPAAEGATELAAELTELGAEVEIAACDTSDRDALAALLAAVPAA
HPLTGVIHMAGVLDDGVLASLTPERVTAVLRPKVDAALHLHELTEGLDLAAFILFSSVAG
VLGNPGQANYAAANAFLDALATHRRDRGLPAQALAWGPWAAEEAGGGMAGELAAADSGRM
SRIGIETLSGASGTEVFDAARTLGAPALVTILLNTKAMRGATDLPDLFRSLVPARSRRRA
ESGSTVDVTAFRRRMAGLTEAARTDELVDLVRAHAAAILGHSGVTSIGKSREFKELGFDS
LSAVEFRNSLAEATGLRLPATLVFDYPNSQSLAEHFAEELRPKDGADGTGAGGDAAAPDS
DEGRIRRLLQTVPMARLRELGLVDTLLELADGRAEHTETTTVAAEEEAIDDMDAESLINM
ALDGLGLDDAIQGM
>B2J679|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MSYIAVPYQIHFEDTMAYGSHHYLTNFRFQCIAREHFFFGGLFNKETFQDVVILTQQGYS
RNMAPVGLGERVVILLTFDEPTRSTTRLCFRVIREDGTPVCCGYQVLVFTSRITGELIPI
PPVLVDYVLQNFGLIERLLDPPFAEKVVAGGKEIKKIFTPEVCELGKLITSRNLANDPSG
VQIVDTYFLTLDKVNITKVNPLAQNKIVFTFPGQGAYDYQTLQTLYQNYPAKKSLFTKAD
ELTQRYLGYSFLTLIQAQSNDEHQFLLQQCPDLDQIGILLTNIIIAELLIEQGLHPDILV
GHSFGELTALTIGGVFDFETSVEIVCQRIQVLRNFASNIGGMMAIACGAQRLTELFSAIK
KTALTVAVINHPQQIVLSGLYTELQQVESELVPLGISCTFLKSRYPFHSALLAPAVASFC
SSLQQFSFQAPKIPVYSPINKAFYTANTDFPQTLAAHFIQVVNFSQAVKILQQQGVHSFI
ECGASRVLTKLVQKNLPSEPEAIAQSVMSDDRNIIEGLQHIVQTYSGQLSHPQPTPENNE
KLHPVVDEAFEYGKWEIEPEEVTAFSSAALSSDSDTNGTNVPIAIVSMGCLLPGADSPQA
YWRNIQDGVTGIVDLGLIDPSLVPDFMSDGSVIPEKTYTLLSGRINQVEYEKGIPYSLEE
FNNLTRGQQLLAKALAQCLNPIHQQVSATKKVHCLLGSTADGIKEYDEALFAESLKYFVE
KLDEPEQLRTTFSNSLQTLLGRKSGEHEFLAPDLCYKRVVQKFLGDGVKTLLLDAACASS
LYTVDIGIKLLQNHESDLVLSGGVFAPGVAMNCLFAQFKGLSATGSRPFDATADGVVFSE
GAAILALKRLPDAIAAGDRIHGIIRGVGTSSDGKSAAVNVPTKVGQVLACQRACENAQIN
PNTIQYIEAHATATPVGDGTEFKSLSEVFDKREANLPPIYLGSVKALIGHTGWVAGTASI
IKVCQALKAQTIPRQYNYKSPNKDIELQGSCLSIPTTPLPWPNNIAGQPRRAAVNGFGFG
GTNANLIIEAYDPSYHRQFSQRPNTHSLRRPLALVGIGTLFPSLNGLQENSVPDIQVKQF
ARETLQLPVKRRLLPDVTDRMDASQYLSVMATEKALRGLGEKALALQSRTGVVIGMPGKT
GRGITVNERLFLDRLRRLLQSKPGHFSQSDIDFERLCQKLFTAIQQANSPSSPYTLIGSM
PNITAGQVCNLFNFNGPNIVIDAGIDSLLETLRIAELMLMSHDCDLILAGSINGYVGHGA
HTSGKDMPTGEAACILALTTIEIAQSHGFPILSTLDVNTSGIQESIVEVAGSNIPIDFYG
ATGVVEIARAVERVSQSREVVAVEWKSASQGQITFSPFPAPQETANEKYIGTQDINSQSL
HQTPTHFYTPSLFPATVEKIAVPRPLEKRQILFLTDQPELWTALAQTQMLKDLNYIVACP
ANKAIADAIQIDLTSEDAIKATVQKLDFSRYDTIVAIKNLNAISDEQLISIDDSDSLLNL
LFAVVRHSYPQLQTGDSALATLCLNAWKTGQLSPYTGLLAGFIKSVARELPKCICKSINT
GAASIKDAWQQLDTELNSQPGKPVEVSYMNGDRQIFQLVSLAEVTKDHTPVLNQNSVVIT
TGGGRGVTAVLMEEVLQRFGCTVVLLGRTDLKSVPAEVLELDEADFAQYESRFYQEQLHR
ERSQKMPALKAQIEYYQAARELHHTLKHLSALPGRFEYVNVNITDVEAVNQVVAKVVKTY
GRIDLVVHGAGIQTSKLLPKRTFTEFQRIIATKLSGLKNLYNACHQYAPNNKVHFHLLTS
AFSYIGNDGQPDYGAANEFMNRFAAYMDSSLLTGSWSTIAWLGWAGIGMTRGSEYAVLSQ
ERGLHAIQAEEGQQLFSLLLNGQATAPINVLLTEGEKNYYQIDVVTAQNNLSPGLAKLEN
KLANKTEENILITPREHIANTKKFSDERQWYVSIKTAPYLLDHLVNDVPTMPATFEQELA
AQAAQALRPNLQLIAIENSKFSRFIKFFNEQEILLKTQATIVTEKNHETVIHVKLLSDFI
HKNGTLLQKDCVHCEMDIRLAANTQAIVGRYETWNGFEGETIQEPYMNPNSPVRLKGMFD
CINNIVIGSNRRRAKFRLKNTTQLRLTSDFCTPAILIDAMLRVATSSGDSNDPRAVFVPQ
GWKKITLTPDLNDWKLNQLHQELFLVGSNSQKTGDTLYCDWLQVMDANDRVLVLMEEAIG
LQKSTQLARL
>B2J016|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MNNISKKVDKDKLEQLNSSQRILLALDEAVKKLKDVERAKTEAIAIVGLSCRFPGGVTNP
EEFWQLLIDGVDAITEIPSQRWHLEDYYHPNPDTPGKMYSRYGGFLQQVDQFDAQFFGIS
PREAIKLDPQQRLLLEVTWEALENAGIIPQEQVNGQTGVFIGITTNDYARLITPGGDLSQ
IDPYYLTGNPLNAVAGRLSYTLGLHGPCMAVDTACSSSLVAVHLACQSLRNQECDRALAG
GVNLILSPENNIGLSKAKVLSADGRCKTFDSEADGITRGEGCGVLVLKRLSDAVADGDRI
LALIRGSAVNQDGASSGFTVPNRNAQENLIRQTLTRANVKPEEVDYVEAHGTGTSLGDPI
EVRALAAVLGAGRTAENPLKIGAVKTNIGHLESAAGIAGMIKVILSLQHQQIPPHLHLKQ
LNTHINWDELPVSVTTQATPWPVGNKQRLAGVSSFGASGTNAHVILAEAPTNNSLSKPQN
AKFIERPQHLLNLSAKTEKALRELVQRYINYLQSNPEKSLADICFTANTGRSHWKYRLSI
LADSTMSALAQLTTWALGQDLPGVVLGEAESTSKKIAFLFTGQGSQYAGMGQKLYQTQAK
FRQIIDQCDQILQPYLDKPLLEVLYPQPDTNSPIDNTAYTQVALFALEYALYQLWQSWGI
KPDVVMGHSVGEYVAACVAGVFSLQDGLKLIAARGQLMQALPENGAMVAVMTTAEQLQPL
LAAYKEKVAIAAVNAPQSLVISGEKSAISAITSQLETAGIKTKPLQVSHAFHSPLMQPML
ADFLQVASQIKFSPPQLKLISNVTGELATTEIATAEYWCRHILNPVEFAASMVTLQQQKV
AICVEIGPKPILLGMGRQCNPTVEGLWLPSLRSRQDDWQVMLLSLAQLHCHGVAVDWLLF
DADYSRVRLHLPTYPFQRQRFWIETVDGQRDQPALISRNGKGRKIIHPLLGQRLPLATSQ
SIHFESQISAASPTFLQDHCIYDATILPATAYIEMALSAGAIVFKTDRVQLEAVSIQQAL
VFSGDEPKTLQVVLTPENTRVYSWQVLSYLEDESNVDNWTLHASGKVGLGNAETHSAAVD
LAGLLSEDSTEISVKEYYQSLHDRGFDYGEQFQAIARLWQGETQAVGSVRLPLPLTADAS
KYLLHPVLLDACFQILGTNFPDNGQQDVYLPVGVEQLQVYQRAGNSLWSRVEKIEFQDVK
QQHLQADLSLVNDAGELVAKITGLSFRRITQKAFQRILAKVLPAPQTTDNWLYQIAWQRQ
NLEPASSNKQPSSWLIFADQGGLGQKLAQLLTAAGDRCIMVSAGAVYQQLQADRYQINLA
HPEDFGRLIQDNPCQGIVHLWSCDATTEPQLTSCGSVLFLLQAIYNAKLPALPSLYLVTK
GTQTVGGQLTPLQVQSATLWGLGRVIALEHPELHCVRLDINPDAPEDHIPSVAQELLVPS
REDQIAYRQGLRYVARLVRSDVAREADVNSQAFQLQISEYGVFENLTLAAMQRRQPGPGE
VEIAVRAVGLNFRDVLNALGMLREYTEQMGITDAKELPFGGECSGIVVAVGENVSHLQVG
DAVIAAQTIGSFASFVIVRSEFVVRKPENLTFEEAATIPTAFLTAYYGLYQQAQLKSGER
ILIHAAAGGVGQAAVQLAQRVGAEVLATASPRKWEHLRATGVKQVMNSRSLEFADQIREI
TSGQGIDVVLNSLNGEYIPKSLEVLSDRGRFIEIGKIGIWDAEQVKDSRPDVGYIPFDLL
DISLENPSLIGEMLGELMAEFQQGSLKPLPVSVFSIQDVANAFRYMAQSKHIGKVVVSIP
QRQMPKETTIQADSSYLITGGLGALGLQVAQWLVEQGAQNLVLMGRRGVSPENQPAIEQL
EQAGARVLVVTADVSQQEDVSQMLATLNASMPPLRGIIHAAGLLADGMLLRQTWENFELV
MAPKVAGAWNLHTLTKELDLDFFVCFSSVSALLGSPGQGNYAAANAFMDALAHHRQALGL
PGSSINWGPWADAGMAAALSSREQARWAAQGVQPIPLEPGLQILAKVVQQNLAQVGVLPV
DWSKFTAQFPSDVELPFLAEFTNAISKVTPQVAELRQQLEAAAPKQRPILLMNYVRSQIA
KVLNLTSTEEIDPKEGFLQLGMDSLMAVELRNRLQSSLGCSVPASLIFDYPTVDALVSYL
IQELWTDRPPEPSTENSPPPAQGIAESELEELSDSEAEALLLSKLDNLKY
>B2J2F1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MEKIAIIALSCLFPDAENPEEYWQNIVNQKDSTSSATVEEIGVDPTIFHNPVKGTPDKTY
SLKGGYIRNFQFNPSEYNLPSEFVAGLDNTFKWSLYTAKQAIEQSGYWGNQTVLAKCGVI
LGNLSFPTKLSNQLFSPIYQKAINPAVRELLQYEDFNLAVPSGTTASLYNAMISGLPASI
VAQALSLSQINLCLDAACSSSFYAIKLASHYLWSHKADVMLAGAISCADSLFVRMLFSGV
QGYAENGISRPLDKSSRGLIPADGVGMVMLKRYSDAIRDGDNILATICGNGLSNDGKGKH
LLSPNPKGQVLAFERAYNEANFSPKTIDYLECHATGTLLGDTTEFNSIETFFGQNQAAPL
VGSAKANTGHLLTAAGMVGLTKVILSMSHGVIPATMNVSEPLTSEKGTISADKIVRTATA
WPNNNAPIKRAAISAFGFGGTNSHLILEQGNTRESVESTPPVPPTKIAIVGMDAFFGNCN
GLDAFERSIYDGTQHFTSLPPQRWHGIENQESVLKEYGLADGKAPVGAYIKDFEIDTLSC
KIPPNEIEKLNPQQLLLLKVSDRAVKDAKLQEGGNVGVIVAAETEFSVHQLQQRWNLSWQ
VKDGLLNQGISLPVEQLAQLETIVKDSIHQPVEIGEYVSHIANIMASRISALWNFTGPAF
TVSAGENSALKALEIAQMLLATGEVDAVVVGAVDLAGGVENVLFRSQFAPINTGVNTLGY
DQQANGWTVGEGAGAVVLKRYEAAKEDNERIYAVIDAMSFAQGNSTLSDALVKPDASAIS
NVCKQAFQMAEIQPTEVNYVEVFGSGVPQEDEAEITGLLQAYPKVGNGLHCALGSVKANI
GHTYTASGIASLIKTALCLYYRYIPATPKWSGVKTPQVWEGSPFYVAMESRPWFVDKGGT
RRIAAINSMGIDGSYAHLILSEEPSQEERDNRYLQQMPFHLFPIAVSDRSTIPDLLNHLQ
KSIEASSSLAARASQTFATFQQQSDPKYVLSITGRNTKDLLKEIESARKGVNNAFENGTD
WQTPLGSYFTAKPLGKTGAVAYVYPAAVNSYIGIGRTVFRLFPKVFEDLKSNNLYNRAAD
VEKLVYPRSLPKLTTRQLETLEKQLLDDSLAMFESEIAFARYMTAIFRDDFKVKPQSVFG
YSLGETSMMVAQGVWSDFEGGSNTLNSSPLFGDKLSGPKNAVREYWGLTDSPNNNFWNTY
VLMATPSQVRECLKHENHVYLTQINTPEEVLIAGDDAACKRVIATLGCNSFPAPFDHVIH
CEAMRSQFEEIKKVNSLPSQNLPGIVFYSAADYQPVALERDTIAHNIAKGLCQELDFPQL
VNRVYGDGVKIFLEAGAGSVCSRWIDKILGSKEHITVSLNRRGMDDHASMVKALAKLLSH
QVNVDLSPLYCKAQDTANSSKATLRTVTLGGKAIAATILSEQNRKLVEDFAGDLRSDRFK
IQHPDIPKVQQSEITDSLNTSKHITQQESHSPNILPQPEEVKPKNIIDNVFQPREQLQSS
ESSAIRQSIPVSFPPVRTQKISSIISMFDLNKTQYQKLNANNSKITKAHTAFLQARQDYS
QQMSEIIQLQLACAQNLLNEES
>A0A3N6IJR2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI98-12|TrEMBL
MTVRLFAVAAETEDGLLAAIHGHADRIRAGRDLPSLARYCHDAAAGTTGLAHRAALTAES
YDDLAAGLDKLVQGWADRTSAPSLSRRLGLVFVFAGQGAQWDGMGLELLATEPVFCAALR
RCDERVRELAGFSVIQQLRAGPAASRLGEIDVLQPTMVSLQIALVALWRSWHVEPDAVTG
HSMGEISAGYAAGALSLDDALLIACRRSALLRRIAGRGALATTELSPEAAHALADASGGR
ICVAGENSPRSTVLAGDTATLTALVEDLDRRGVYCRMVRGTVASHSHYVDELRDDLATAL
RSLSPVPSRVPIYSTVTAAPVPGTELGPEYWMRNLREPVRFAATTGRLAEDGHEIFVEVS
THPVLLSSLRQTLESAGRPGEVLPSGRRRTERRAMLSSLGTLFTYGRDPHWPTSAPPGPA
LTPYQAAVLEAVRCPRSSPVAAGSG
>A0A0F4Z041|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Rasamsonia emersonii CBS 393.64|TrEMBL
MDDLVQSTAFMPPIVDSMDSCHVFLFGDQTVSFERDLQRLLHVKDNNALRSFFDKVGFSL
RRELSNLPSSQQEWFPRFTTVIDLVSKLDETEGRPVLKFALLCLCEIAQFIRYFGEGSRP
YPQVANSYLLGLCTGSFAAAAISTSQTLSELIPAGVEAVLVAFRTALRSFVLHNDLEGPI
PGLSRSWSVVVDAQEADARALIESFCSEKGLPRSSRPYVSSVMPTNVTISGPPSLLQEFL
TANSFRAHHLPIELPYHAPHLFDAADVDEIVGEFHDSVLESYKQRFTLLSAASGEPVAAD
SFKTVLRTIVSDTLCKPLRWDKILPVITDTVSNEDFKHCILYPLSSTSSQLLSSTLTKNT
SVQVSINNLVGSGSSAPTGRFEQSKIAIIGYSGRFPDAASNEEFWDLLHAGRDVHRTIPE
DRFDWKAHFDATGKKKNTSRIQYGCFIKEPGLFDTRFFNMSPRESENTDPAQRLAITATY
EAIEMAGLVPNRTPSTQQDRIGVFFGITSDDWREVNSGQNVDTYFIPGGNRAFVPGRISY
FFRFCGPSLSIDTACSSSFAAIQTACAYLWRGECDTAVAGGTNVLTNPDNFAGLDRGHFL
STTGNCNAFDDGASGYCRADAVGSVILKRLEDAEADNDPIFGVIVGAYTNHCGQTDSITR
PHEGDQASVFKRIMRNAGVNPLDISYIEMHGTGTQAGDATEMNSVLSVFVPGRERVPRHP
LYLGSAKANVGHAESASGVSSLIKVLMMMKHNEIPPHCGIKTKINHNYPLDLNERNVHIA
FKPVPWHRKDCYNGKRTVFLNNFSAAGGNTAVLLEDAPLPQQSGNENDPRTTHLIAVTAK
TPKSLSGNIAALIRFLDDNPDTYVPALSYTTTARRIQHNYRIMCAGSDVQTLRESLVAKS
NIPDLKPIPNFSKIPKIVFVFTGQGSFYAGVGKQLFESIWQFKSDILRFDGIAQREGFPS
FLSAIDGSTEINGDVDPVIAHLALTSIQMGLSRLWISWGIKPSATIGHSLGEYAALHAAG
VLTASEVIYLVGTRAQLLSASCTKGTHSMLVIKAPLDVVRPLFAGSRCEVACINQPTSNV
ISGPGYEIDALAKQCQSYGHESVKLDIPFAFHSAQVDPILEAFEVAAGSVRYEKPSIPYI
SPLLGQVISDGTTLGASYLTKACRNAVNFQGALEAARAASIVDDRTIWLEIGSHPACSGM
VKGTFGSQTLTIPSLRKGTDTWKVIASGLESLYLNGIEIDWNEYHRDFKSSHRVVGLPRY
SWDLKNYWIQYRNNFCLTKGDDPEPQQIPAAVPDEQQTPVYISPSTQRVVEEDHAADIST
LLVESDIHDPRLAPVIQDHKVNGVPLCPSSLYADMAMSVADYMLKAKNKRSDNAGLDVAD
VKVEKPLIATPDKGSQLLRVSASADWSTNVVSISLYSVTSEGKKLADHATCQVRITEKQT
WLDDWKRTSYLIRSRITSLNKAVDEGDSHKMKGGIVYKLFGAVVDYGPRYHGLQEVVLDS
NELEATAKVSFQVDDGGFFLNPCWIDSLGHIAGFIMNGNDNVNSATQVFINHGWDRMRCA
TKFSKDKVYQTYNRMQLVSGTMYAGDTYILDEGNIVAIFEGVKFQGVPRRVLDHLLPSKT
AAPKNAQKASNTTTPDAKVPTKTKPASAPVAKRSPAATKQTSKPAAVSQAKPSNNSIVPR
VMAIVSEEAGIDSSELSPNDEFGDYGIDSLLSLTICGRLQEELGLSLPSSLFADYPTVKE
LSNFFQGSEQPLSPAESSVDDQDIQTPEHDTDLEGTSSEYETRATSVAELNDVIEIIRAT
IAEETGVAIADVTPSTSFAELGVDSLLGLTIMGKLSEELEMDIPSTLLTENDTLDEIESA
LGLKARGSKDSDPVSRGPGVLRLEPDKPPHSTSVLLQGNPKSATKILFLFPDGSGSATSY
ASLAKISSDVVVYGLNCPWMKTPQDMTCTLEDLTAKYLVEIRRRQPHGPYYFGGWSAGGI
CAYEAAQQLARQGEETARLILIDSPNPIGLENPPQRMYDFFESLDFFGMNGKAPPSWLRP
HFNAFIRLLDEYKIQPFSGRPLDTHIVYARDGICKHPSDPRPEIRPDDPREMLWLLNNRT
DFSGSGWAQLVGAQNLKISVMDEVNHFSMVAPEPKIDKLSAFIRQAME
>A0A3N6FGF9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI96-15|TrEMBL
MLRQPPEGRRATLLDLVRAQVTTVLGHADAGAIEPDRAFKDLGLDSLTAVDLRNRLGALT
GLRLSATLAFDHPTCSALAGHLLGEIFGADALEADHTAAAAPGRDGQDAFGTPTSEDPIA
IVGMACRYPGGVATPEDLWRLVDSGGDAIGPLPAGRGWDLDALYDPDPDTPGRAYVREGG
FLHDAGRFDAEFFGISPVEALATDPQQRLLLETGWEAVERAGIVPATLRGSRTGVFVGSH
YQEYGPRLHHAGQGAEGHLITGTAGSVVSGRIAYVLGLEGPAVTVDTACSSSLVALHMAV
RALRAGECDLALAGGVAVMPGPGALMGFSRQRGLAPDGRCKPFAEAADGTSLAEGAGVLL
VERLSDARRSGHRVIALVRGTATNQDGASNGLSAPNGPSQQRVIRAALADARLTTADIDA
VEAHGTGTRLGDPIEAQAVLATYGAGRDAAAGPVRLGSVKSNIGHTQAAAGAAGVIKMVL
ALHHGVLPRSLHLDKPSDHVDWASGDVELLRDPVAWPVGARPRRAGVSSFGISGTNAHVI
IEEAPREYPAPDAAEPTRDAPAPTLPWVLSGRSPAALRDQARRLLAHLRQRPTDAGPAPH
DLAVALATRRSLFTHRAVITGEGHEHLTAGLEALAAGRPAPHLTTGAAQAGRTAVLFTGQ
GSQRAGMAARLHRTQPAFAAAFDAVCARFDTLLPDEPSLRDIVFDTGESAARTLTGTLHA
QCALFAVEVALYRLLASWGLRPDAVAGHSVGEITAAHVAGALSLEDACTLVAARGRLMRS
LPEDGAMVAVRLSGAEAEVAPLLADRAHEVSLAAVNGPDSVVLSGAADAVEEIVVELERR
GARTRRLTVSHAFHSPLMEPVLAPLRAELADLDGAAPQIPFMSHLTGGYLPSDRPVEPEH
WVRHVREPVRFADGIAALAADGGTTFLEIGPDAVLSAMGQDSAPEAEFIPTLRAEESDTV
ALTRAVGQLFVRGADLDWSAVLAVPDGAPHTADLPTYAFQRDDYWLPSDEGTRRPEDHSD
DAALADELALGDAESAAALLPLLTAYRRRREEDGRIDGWRHRASWTTTAVPPAAPAGAWA
LPVAAEQAADPWVTGLVAALTAQGMKPVLLPCADGDALVEQLRALDEDFGPVSGILSLMA
LASGQHPEHDAVPRGVGLTLALLRTLEESGVRVPVWHATRCAEAVGAAEHVRHPEQLGVR
ALGRVAALESSGQWTGTVDLPERIDGWTGSRLAAALAHSAADGGNGSDAAFENDIAVRGA
GLFARRVIQAPAPTPVDTGAATPWPPTGTVLVADGTGPVGRQVALHLARGGAEHLLLVSR
PASADSTSAETADALCAELSALGARADIVTRDLGERAEAAALLEGLPPTGPLTVVVPTRP
ASGGSALAQQTAAGLQEALRTDALAARNLHDLTRDRAEPAAFVLLTTLTATLGAPGRAGR
ALSDALLDALTEERRSAGLPVTRVALGPWTNEKTAPNTASGIAPDATSETAPDAAQGTDH
DSVHDTAARDGGLLPMRPALALRALDRVARAQETGTAVFDADWKRLAAHVATTPGAAPAA
RLFDGVPAFRDALRGVGALHEEPSTEDPDAFLRRLGTLPARERSAEMLRLVRTQAALVLG
HDSDDAVAPDRGFVDLGFDSLTATRLRHRLGAATGLQISAATVLGCPTPGSLADHLLELC
TAPRTRTRPRLRPRNRE
>A0A2S9YVD4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Enhygromyxa salina|TrEMBL
MIQGPRDPRSKGSDEDHEPVLTWLMDAMSRTLGIEPSRVDPNTRFREFGLDSEQITGLVA
RLASHVGHPLSPVAPWEHPTPLALARHAVAIQASASPTLGSPSLGGRATNPGASMSSEPI
AIVGIGCRLPGSVYNPEQLWELLCSGGTGVKQVPSDRFDVKEYLDVDRAAPGKMTTRWGG
FLDQVDQFDATFFGISPREAQQMDPQQRMGLELSWEALEDAGVDPLSLRGGNVGVFVGAM
WCDYARLTSDELTDIDQHTGTGADTSIISGRISYTLGLEGNSLTVNTASSSSLVAVHLAC
QSLRAGETTMAIAGGINLILTPHGTVVMTKLGTQNPAGQCRAFDAAANGYVRAEGGGLVI
LKPLSRAIADGDRIYCLIRGSAANNDGFSNGLTAPNPKAQESVLRAALANARVNPASVHY
VETHGPGTILGDPLEASALGAVIGSAHPADRPLRLGSVKTNLGHLEAAAGIAGLMKTALS
LYHRMLVPNLHFEQPNPHIPFEQLHLSVQTELEGWPAGNEVPRAGVSSFGYGGSNCHAVL
EAAPKSEALLLPLGSVTAAGLRRQVLAALDFAFELTTWNETAALCRALSERTGPGQHRVS
LMLNAPEQLVDGLSALLAGGLRNLDAAPERPRLVFVCSGHGSQWLGMSRTLLLGEPVFRA
ALEAVDREVESLSGWSVIDELLADSIRSRLDEAAIVQVVLFAVQVSLGALWKSWGVEPDA
IVGHSVGEVAAAHLAGILSLPDATRVVVERGRVVAHLAAGRGAMLAVALPEAMLLERLGD
AAKDLVIGAFNSPRSTVLSGPRQAIEDAESLLAQRGVRIHRVDIDFASHSPEMLPLVGPL
ETALDGISPRPARIPMMSTVLAQPLSGPECTPSYWGRNLRSPVRLRQAIELLADAGPTVF
VELSSHPTLLKSIEQTFDGSALRFWALPSCWRNEDERGSMLKSLSQLFALGFDPEWPAVW
SHAPQLKMLRPEIEERMHDAVGDHEVEIWEVESRYRVPLLISAKGELALRAQAERLHAFL
LAHGDVTLADLSHSLATTRAHFERRASVTVTDIADALDALDMLARGASDSRTVEGEARVS
GKVAYVYSGQGSEWPNMARSLAQISDRFREQLEACDRSLSEHLDWSVLDVLNGVEGAPAL
DRTDVVQPVLFAVSAALTTLWRLRVGIDPDGIVGHSLGEVTAAYVAGALSLDDAAKIVAL
RSRALARLTGRGAVASVPLSASELEVHLKPHGERVSIAAYDGPNATLIAGDPEVIDALLA
ELEVGTRLPINYAIATPQIEGVRDEILAALDGLKPRAVVTPLYSTVRAEKLVGRELDAEY
WYRNVRMQTRFADTIAKMIADGYRFFIEVSPDTMLREALDACFLKAEITGVAVGSLMRNE
GGPARLMRSLGELHTRGLEIDWTKISAGRRITLPTYAFQRNRFWVETKQQRRPTADATTV
ELPAADVGFWSAVETGDLDTLANALNVDDELHRNSLASLLPALTSWRRNHQERTTLNAWR
YRVGWKPMQTAPALGSLTGVWMLVTASEPDDPELVNLVSMGITGAGGTVVRVPVDEDEPD
REDMTNRLLRAGLESSPPRGVVSLLGLVEDPLPEQPTLPAGLPLNLVLTQSLGDAGIEAP
LWLLTRGAISIGRADALSNPLQAMAWGLGRVIALEHPDRWGGLIDLPLTLDPKATRRLLA
ILSQEEREDQLAIRNTGVFVRRLERAPLTELADGKPWKPRGTILVTGGTGALGARVTRWL
AAAGAEHLVLTSGQGPDAELMELGTRVSLVACDTTDRDAIATLLDQLDADGEHLSAVIHA
DGASQNSSINDTTVDELARVAGAKVAGARYLHELLKEHELDAFITFSSIVGVWGSARQSG
YAAANAYLDAFVEQRASLNLPAMSVAWSAWATGNADDASQHELRRRGLEPLDPQLAFQAL
QQGLEHGDVNLTVADVDWARFTPSFAAARPRPLLDDISEARAALDTSSSSSEPDEARLLA
RLRGLSETERLRALVNLVLGETAAVLGYHDASRLDPNTGFVDLGLDSLMAVEVRRRLQRE
TGLNLPATLAFDHPSPQHVANFLLEGLAAALGMAAELDDDHRDRAEAPPTHEPVAIIGVG
LRMPGQIVDLRSMWKFLASGREAVGPLPPSRWNVDEFFDPDPESKGHSYVREGSFLDDID
QFDPAFFGISPREAKNIDPQHRSLLEAAWQALENAGVVPSSLRDSKTGVFVGLGPSDYDH
LRQDLGEAYTFTGTQTSFAAGRLAFTLGLQGPALAVDTACSSSLVAFHLACSALRNRECE
LALAGGVQIMAAPDVFVQLSRTRALAPDGRCKTFSANANGYGRGEGVIVFTLERLSDARK
NGHEVLALVRGTAVNHDGASSGITAPNGTSQQKLLRQALEDAKLAPTDIDYVECHGTGTS
LGDPIEVQAIAAVYCEDRTPDNPLQLGAVKTNIGHLEAAAGLAGVAKLVACLQREAIPAS
LHTKPRNTHIDWQSLTVEVTDSHRSWPRREGGSPRRAGVSSFGMSGTNAHAILEEAPLDD
AHVVTPEMPVPPELPLVLSGRTNTDLVAQAKALAAHVRELGPDNAWAISVLDLGYSLATT
RSHFPVRLALTIDSDAPADLLLDMLDGFAKIGAEPRNGAMTPREHRKGKLAFMFTGQGAQ
RPGMGRDLYNRYPTFRDALDTVCAHLDFHLDRPLFELMFSEPDTPEAALLDETGYTQPAL
FALEVALFRLWSAWGVTPDILIGHSIGELAAAHVAGVLSIEDAATLVAARGRLMQALPRG
GAMVSLQAAEDEVRPLLDARIGIAGINGPMSIVISGDEQAAADIATHFEAMGRNVLRLAV
SHAFHSPRMEPMMDEFRRIASRLDFKPPKIPIVSNVTGERATAEELTSPDYWVRHIRQAV
RYLDGVHTLEAEGVTTFIELGPHAVLSGMTPPCLSDKVLRRAVVLPTLHKRKPEVETLNM
VVAGLHVHGYSFDWQAFYAPYGPKRVELPTYAFQRQRFWIDRSDGRSSNVSSVGLTDAEH
PLLGAAIRLADSDAMLFSSRLSLSEHAWLADHVVFDATLLPATAFLELAQVAALRVGLDR
VDELTIERPLALPSKGGVLLQLSVGVPDETGRRSLAFFARPDAEADAPWRRHASGYIGQG
PRIADFDLHSWPPPGAEAINFGPGLREGYATLEEAGLAYGPAFRGLVGAWTHGNELLVEV
RLPEAPARDAERFGLHPALLDAALHPLVLQFLGQDRPALQLPVTWEGAELYATSTTALRV
RFTPKPSEGAVSVAVADQSGEPVAFIETLVTRPATAEHVREALVAQRFDGLYAVEWSIPL
DTGAVDSSGEWSVVGHDGGLELASTLARASVSVREHPNLAAIQAELDDDRPAPEVVVIPW
ITDVHAGERVANPHDATHRALAALQTWLGDARFQDSRLIFLTRRAISTEAREDTLDLAAA
PLWGLIRTAQVENADRAITIVDLDTEEVSLWALPAALACDEPQLALREGMMLAPRLARPP
AVERLTPPAGSANWQLSVSTKGSLDNLILAERPLATGPLGPDEVRVAVRAAGLNARDVLN
ALGMYPGEADALDTKVGLDLGIEGAGVITGVGSQVQHLAVGDRVMGVMPAAFGPVAVADG
RLLVKVPERWSFEQAAAVPIVFLTAYYALVELAKLARGQRVLIHAASSDIGLAAVALAQH
LGAEVFATAPERKLAALRQLGLKDDHIASSETLGFEQKFLSATGGRGVDVVLDNLDAEFV
NASLRLLPEGGHFAELGIRDIRDPARVASEYRGVSYHAVDITRLAPELIQDMLVELLALF
EVGALLPLTTSTWDLRNAGEAFRSLSNGGHVGKYVLELPRGFDPDGTVLITGGTGALGSL
VAKHVIERHGARNLLLVSRRGDESPNAKRLAVELELLGAVVTLAACDVADRDALRQLLLG
IPQAHPLTAVFHIAGVLDDGVLASLTPERIDRVFHPKVDAALALHELTVELGLELAAFVM
FSSIVGIMGNAGQASYAAANTFLDALCARRHAAELPATSLAWGPWGGEGMAARLSDADRA
RMRRRGMVPLAPVDGLALLDTALGRPDAMLVPVHLDTSSVSTHGEAPPTMLRGMVRAAPR
PRATASVAATSSSTSLQQRLAPMSDAERDRALLDLVRSEIASVLDLGRPESLGPDRPLKD
LGLDSLVAVELRNRLQTVTGLRLPSTLLFDYPTPGALATMIHGELSLADVGATISPAVST
ELDRLETILRAMASSSAQHTGITDRLRKLLGLFGVKTLEAADDDDDDDGDEESFDELSDE
ALFDMIDSEIEGMNS
>A0A5P9PGR5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Amycolatopsis sp. YIM 10|TrEMBL
MADDGKLLDYLKKVTTDLRQTRRRLQEAESATQEPIAIIGMSCRYPGGVRSPEDLWRLVA
DGRDAIGPFPGDRGWDLGALFSTEPDRSGSSYAHEGGFVDGADEFDAAFFGISPKEALAM
DPQQRLLLELSWEAFERAGIDPHTQRGNRVGVFAGTGSQDYEQLLNAHPDLSEAYGGTAT
SAAVLAGRVSYTFGLEGPAVSVDTACSSSLVALHLAAQALRQRECGLALAGGVMVMATPG
VFVGFSRQGGLAVDGRCKSFSDNADGTAWGEGAGLLVLERLSDAQRNGHRVLAVVRGTAV
NSDGASNGLTAPNGPSQQRVIRQALANAGLSASEVDAVEAHGTGTTLGDPIEAQALLATY
GQGRTADRPLWLGSLKSNLGHTQAAAGVGGVIKMVQAMRHGLLPKTLHVTEPSSHVDWTA
GHVELLTEPVEWPEHEHPRRAGISSFGVSGTNAHAVIEQAPAEEPAEDRAVPPIFAVSAR
TAVALRAQADRLRALLETPGAPEPAVVTSALATRAALEHRAVVFAEDRESVLTGLNALAD
GETASNLLQGHVQGEIAPAFFCPDLETPRSLGWLLDAEPAFAIAVGECAEALGIELAALV
RADTIADEMARPVWWAVQVSLAKLWASYGVEPSAVGGIGVGAIAAACITGALSLTEGAEL
AAAPEAGPPDARPPASGPTWYPASPDGSVEQAVSAIRADGFEVFIELSPAATPRVADAVT
DSALVAAPGADFHASLAGAYLRGVRVDWAADGARSVDLPTYPFQRERYWVDSPAEAAAVD
PVSAGQLAADHPLLTAVVAEPESGGVVLTGRLSAATRPWLADHRVLGSVIFPGTGFVELA
VRAGDQAGCPVLDELTLLTPLVLPETGAVRIQVVVGGAGDAGAREVRVFSRAEGAAEDEP
WLRHATGTVSAGSLEAVAEPWPPMNGTPVDLTGFYAGLAEVGLDYGPAFRGLEAAWQADD
AVFAEVTLPEGERGGDYGVHPALLDAALHAVSLMSTADDGAMLPFAWSGVRLFATGATAL
RVRIRPVRDGEFSLEATDPAGAPVLSVSSLLLRRASAEQLEGSRPGAPVFGVEWVPLAAA
GTGPVEYGTWDELDGAVPGVVALPAGGGVDADSVRAATAHVLGVLQSWVAEERFADSKLV
VVTRGAAGLPGEDVSDLAGAAVWGLVRSAQSEHPGRFVLLDADAGLSAVLPATLASDEPQ
VLVRDGVVHAARLTRVPADRNEPAVTFDGTVLITGATGALGRVVARHLVAEHGVRSLLLL
GRRGIAAPGMGELVAELAGAGAAVEVVACDAADRDALREVLADAPVRGVVHAAGVLDDGV
LSSLTPERLERVLRPKVDAALNLHELTADLPLTAFVLFSSASGVFGAPGQGNYAAANAFL
DGLAEHRRVNGLPAQSLAWGLWSGSGGMGGTLDGADQARISRGGFLGLSTEDGLELFDTA
MGAAPAALVTAKLDLAELRAQGDALPSLLRGLVPPARRNAASGSGSSRILALPPAEREGA
VLDLVLTVVANVLGYASSGAVEPGRAFRELGFDSLTSVEFRNQLGEAIGLRLPMTLVFDY
PNPVALARFVLDELSGSAQTAVAATTVAPITDDEPIAIVSMACRYPGGVRSPEDLWELVV
QGRDAIGEFPADRGWDVERLFDPDSVRPNTSYVRHGGFLYGAGEFDPEFFGISPNEALIM
DPQQRLLLEASWELFERAGIDPGSLKGSATGVFTGLMYHDYAGSTSTGAIASGRVSYVYG
LEGPAVTVDTACSSSLVGLHLAVQSLRSGECSLALAGGATVMATPELFVEFSRQRGLAKD
GRAKSFAAATDGTSWGEGVGLLLVERLSDARRLGHPVLAVVAGSAVNQDGASNGLTAPNG
PSQVRVIRQALGSAGLSSSDVDAVEAHGTGTSLGDPIEAQALLTAYGQERDEPLWLGSIK
SNMGHTQAAAGVAGIIKMVQAMRHGVLPKTLHVDEPTPRVDWSSGAVELLTESRAWPERG
RARRAGVSSFGISGTNAHVIVEEAPADGLAFLFSGQGAQRLGMGRELYETYPAFAAAFDA
VCAELDPSLREVIWGDDPELLNQTEWAQPGLFAVEVALFRLVESWGIRPDFVAGHSIGEI
AAAHVAGVLSLSDAAALVTARGRLMQALPTGGAMVAVQASEQEVLPLLSDQVSIAAINGP
EAVVLSGEEAAVLAVANQLSGKSTRLKVSHAFHSPLMEPMLAEFAAVVEQLSLREAVLPF
VSSALEADVTSPDYWVRHVREPVRFADAVRELESRGVARYVELGPAAVLSLLGPRCVSEG
TFEATAEFIERVRPRAVPWVLSAKNEEGLRAQAASLLSWPENNNADVAYSLATSRPSLDH
RAAVVGTSRDELIQGLSAFAAGRSSAGVVRGVAREHGGTAFVFSGQGAQRLGMGRELYET
YPAFAAAFDAVCAELDPKLREVIWGDDSDLVNQTEWVQPGLFAVEVALFRLVESWGVRPD
FVAGHSIGEIAAAHVAGVLSLSDAAALVTARGRLMQALPTGGAMVAVQASEQQVLPLLSD
QVAIAAINGPEAVVLSGEEAAVLKVADALGCKKTRLKVSHAFHSPLMEPMLAEFAAVVEQ
LSLREAVLPFVSSALEADVTSPNYWVRHVREPVRFADAVRLLEERGVTTFVEVGPDAVLS
SLGGFTPLQRRNKSEELELVTAVANIHTRGVPVDWHAFHDGRARRVDLPTYSFQHQRYWL
NTQDYWRDAWAGSTSGLGDVTSAGLEAAEHPLLGAVVPGAESDTVVLTGKVSPATDSWLA
DHVVLGSVVFPGTGFVELAMRAADQVGCTVLGELTLEAPLVLPDDGVALQVVVGEPGPSG
ARPVSIHSRDADLPWVRHATGTLADEAPVTPATWSLPTGTPIDLTGWYANLAEAGLDYGP
VFRGLQSAWRTDTEVFAEVRLPAGAEDTGFGLHPALLDACLHTIGLLDQHDTPVLPFAWT
GVRWYATGAAAVRVRVTRTGPSSVALSIEDEQGRPVAEVESLALRAVSAEQLAEARRGLH
ESLFQVDWSPLPPADAAPVPVQTWDSLNGVVPEVVVLPGGGTGEPVSLVVGRVLTVLQTW
LEDDRFASSTLVVSTREAVSLAGEGVSDLAAAAVWGLVRSAQSEHPGRFVLVDVDAKSEL
SAVLPAVVRSGEPQVAVRDGVPHLARLVRVPDEPTEPAEHFGPEGTVLITGGTGALGALV
ARHLVEARGVRSLLLAGRRGSAAPGVDELVAELTGLGAAVSVVACDAADRDALREVLADA
PVRGVVHAAGVLDDGVLSSLTPERLERVLRPKVDAALNLHELTADLPLTAFVLFSSAAGV
LGAPGQANYAAANAFLDGLAEHRRAEGLPAQSLAWGLWSGSGGMSGDADRQRMNRSGVDG
LDAEEGLALFDTATRMDTPVLVPMRLDVKAFADGDFPAMLRTLVPTRRRRAADSGAAVAT
RARLAELSESDRAAALLDLIRAEAAALLGHAGPDAIDPGRAFTELGFDSLTSVEFRNALN
GATGLNLPPTLVFDHPNGQALATHLGALLGDSGGDADPDEEIRRVLRSIPLDLLRETGLL
GRLLELGGGGGAPVLNTDDAIDEMDADSLIGLALEGLDSDASHPA
>G6FS67|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Fischerella thermalis JSC-11|TrEMBL
MSAHSIEIALAQLEEQINNCEKAVTRFVEVKKRMSDNSMGIEKMNRKLQYNPIAIIGMAS
LFPQAKNLREYWQNIVNKLDCITDIPPTHWSVEDYYDPNPRTPEDKTYCKRGGFLPHVDF
NPMDFGIPPNILEVTDVSQLLSLLVAKQAMEDAGYGESREFNRETVGVILGSAALKLGIP
LSARLQYPIWKKALKSSGLSDEDTQKIIEKIKSAYVKWDENAFPGMLANVISGRIANRLN
LGGINCTVDAACASSFAALKMAISELVEHRCDMMLTGGVDTDNSITAYISFSKTPAVTPS
ETVRPFDAQSDGMMLGEGIGIVVLKRLEDAVRDNDKIYAVIKGIGTSSDGRYKSIYAPRQ
EGQVQALRRAYEDAGFPPETVGLIEAHGTGTMAGDPTEFSSLREFFTENNSKRHHIALGT
VKSQIGHTKAAAGAASLIKTALALHHKILPATINVTEPNPKLNIKNSPFYLNTETRPWIR
SEGEAPRRAGVSSFGFGGTNYHVVLEEYEGEHNQAYRLHAAPSEIVLFAQTPAELLSSCQ
ETLAQLQSEAGNKNYVELVEACKTKEIPQGAARVGFVAENSAEACKLLQISIDLLKNKPT
ATSWEHPQGVYYRAYGMELAGKVVALFSGQGSQYLNMGRELVMNFPEMRNLYGYMDSLLR
KDNLQPLSEIVFPHPVFEETEKNAQVAALQKTQYAQPAIGMLSAGMYKILQQSGFKADFV
AGHSFGELTALWAAGVLSDADYCFLVKARGQAMAAPQDPNYDTGAMLAVKEDLSKVEAVI
RNYPQVAIANFNSPCQVVLAGPTNAITQVKDALHKQGYAAVSLPVSAAFHTPLIAFAQKS
FAIAIKNVTFQIPQIPVYTNVTGKEYPKEPALIQKTLETHLSNSVLFKQEIENIYAAGGY
CFVEFGPRNILTNLIKDILGDRPHMAIALNPSAQKNSDHSLREAAVQLRVAGMSLKNLDP
YQLPPVIAEPPKNKGLNVKLCGSNYVSDKTKMAFEQALHNGQTVKLQPSETTITVNSTPV
ATPAIALPQTNGTNGHSKQPHSVKDTVQMVKGKEIKSNGNGNSQSLIPTSHTPHLPIPEF
PASRSPMQPEIPDKLVNYQKVLESLEYVLTQFQQNQSENLQVHSHYLSHQMEYAKTFFQL
MQQQNSLLANGKHSADAAKLKPSIIESLDRSMMQFHAQQGETLRIHEQYLKEQVEYTKNF
FQLVQQEYSQLINEGATTQPVISTNGKIGTPEEVKIIKEVTQVTEVKPVKETTQENTSLS
SPTPPTSATPTVSTPSATPAPTIDLSDLDQTLLAITSEKTGYPIEMLELDMDMEADLGID
SIKRVEIMGALQEKYPDLPKPSNVEELAELRTIGQIVQYLQSLVFTPASVEDKKDKGNNI
ESIFTPHLPTSPSPTPDLSSGVPEFSNDSTAVSESVAVAAEPIITVTETATSTAEVDLSN
LAETLLAITSEKTGYPVEMLELDMDMEADLGIDSIKRVEIMGALQEKYPDLPKPSNVEEL
AELRTIGQIVEYLQKLAGAEKKKQQHESVNQLDESVPNVQRRPAKLQILPPPDFWEFPIP
EGHIALITDDGSLTTTKVAELLNQRGWKVVVLKLPPSLVPEKSPLPAGVNRVTLQDATEE
HLQQQLAAIATHYGNVGAFIHIHPVFQANHNSSVAYFPEEKAIIKQVFFIAKHLKKSLNA
AANHGRSCFCTVARLDGAFGVEHKVNFGAIGAGLFGLTKTMIWEWPKVYCRAIDLSPDFS
AETSAQYIVAELHDPNRYLTEVAYGSQGRVTLVSVPDR
>D9UBV1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces pristinaespiralis|TrEMBL
MTTPPSGPDLGQDPNAVAVVGMACRFGPATSVEQLWDLLEQQRSGIRRYSTDELIALGHD
PRTVRHEAFVPAGAVLEDADAFDAEFFGYSAQHAEWLDPQQRLLLEVAWHALEDAGFAPD
ATGLRTGVYASVGQPVHPPVRITELDAAGMMRFSSTDKDFAAGRISYKLGLTGPSMSVQS
ACSSTLVGLHLAAEALLAEECDLAVVAGASLHFPQAGYLAAPGMILSPSGECRPFDDTAD
GTVFGNGGGALVLRRLADALRDGDPVRAVLRGSAVGNDGARKMDYHAPSPEGQEAVIREA
LAVAGVDPHSVGCLETHGTGTPMGDPIEFAALERVYGGDRPHPAVIGSVKSVLGHLNTAA
GVAGVIKAVLALEHATVPRQVPFTAPNRALGGTGNLRIASQDATADGWPVPDGPRRAAVS
SFGIGGTNAHAVLEQAPPTIRPEQPPHAGQAGQNGPAEHAGQDAGDGPVRWALLSAHTET
ALRTWAGALAGPAGRLPLADVVHTLRTGRSHRRVRCALSAATPGELAVKLRALADGGDLA
ADAAPKDLQPWLTGQGPLPDAGPQSHAARRVRLPGYPFARTRWPRPGDDGQTRTVRPDEP
VAADHVVAGRPVLPAAAQLDLALRAARRSAPTATGLADIAFHRPVEVTAPVTLRTVTDGD
TVRIVSDHTHTQARVVTDPAAPPAPLDVAALSAAHPDSAEPAELYRYFEDNGVRYGPAFQ
VLRELRHGPGGALARVAATTAAPADADGQILSPYVLDGALQTVIGCVLREDLGGQTFIPF
AVDALNVHGPLPDEVWVQVRPRRLAGGGRQVRKYDVTVGAPDGTPALTLEGLALRPTRPT
TPTAPTTPGSAGSAVSDGAVVPAGVPGAAVTRLPADVHLFTPAEVPFTAPDADAAAAGTG
GWGGPLVVIGETPLEGADLRLPDPPDAQAAAAAGADLAGRLPEGGVPVVVWPLPADPGSG
PGADALRVLALLRALLGPLARRGARIVVPHPAGGLDDTAAVTGSGLAALGRSLAGENPRF
HLTALALGPGTTPAALTRAVRAAAAHPPTARRLSTGHEGALTEPVLRPWTVPAPAGPAFR
HGGRYWINGMGALAALLAGHLAGTYAAHVVVTGRSPAEGERAAELTRLSRHAARTGGSVT
YHRLDSTDPAAVRAFADRLHGEGTVHGVLHCAGTLRDSFILRKDSADADTVIAAKLTSAA
VLDEATAHWPLDCFVVYSSVSGALGSPGQADYAFANAAADELVARRARRVTSGTRHGRSL
SVAWPYWADGSMRTGGDAEQILGAFGMRPMPADVGLAVLETLLAAPAADPAPVVLFGDLP
QLRASFPLLTGPDPAPAAAPAPVPAVAAPAAPAPAPAPVPAVAAPAAPAPAAAAGALEDR
LRAAVAEATRTPVGDVSPDRPFDDLGIDSLLAIRVVELLEKDFGRLSKTLLFECRSVAEL
TEHLLEEFPERCAELTGTTTETTPGTTPGATPEAVTPGTGAAGAAVAVSAGPPQAEEPPA
SSTAPLDTTPAPALPAGAAGRAELPGGSGDIDPRAVAIIGVAGRFPQAEGLDELWANLLA
GRDSITEVPRERWDAEALYDPDRSRVDRTYTKWGGFLQGVENFDAPLFSISPREAGTVDP
QARLFLEACWAALDDAGYTPDTLVSTADPVHRKDVGVFVGAMYGEYQLHEAEERLRGNPV
LANSAYWSIANRVSYFFDFQGPSTAVDTACSSALTAIHLAVESLRAGSSKVALAGGVNVL
IHPNKYFMLGQGRFAAGDGRCRSFGAGGDGYVPGEGVGAFVLKPLADAVRDGDHIHAVIR
GTAANHGGRTNGYTVPNPRAQADLVTKALRDAGLTAGDLDYVEAHGTGTALGDPIEIRGL
VSAFARDGVKGAGDLPIGSVKSNVGHLESAAGAVALAKVLLQMRHRTLVPSLHATPANPE
IDFGRIPFTVQQSTAPWHTRDGAARPLRAGISSFGAGGANAHIVVESPPPSAPRTPGGPQ
QVVVFLSARTDQALADTARRLHSHLTAARARGQEPRLADIAHTFAVGRPALERRAALAAD
SLDALLASLEALAAGRPRPWRRTEAAADDPVRLWLDGGRVDRATVSGAGPGARRIPLPHY
PFERIRCWYDLQIEHLHHKGLGTATAEPALSRPHLRDFGRPHTPAPAAAPAPSPAADPAP
TPAPRRAPEAAPAPAPVPRRVEPAPALVPRPAPASAPAAPGAVTPPATDRPDPQETPPMT
RDRKISLRPLGTAPTPAPAPAPAPAPVSVAAPAPVPATPTPAAAPAAPVAAPSVAPVAGA
VDPAVADRVAEEVGEVLAGVLYMEPADLDPEQSFQMLGVDSILSVEFIALVNAKYAIDIK
ATELYDHPTPAAFARHVAATLGGTPPPAPAPHATTPAPAAPAATAPAAAAPVAAGERTAA
VLETLREQLAQTLYCDVWDIDTDATFNSLGLDSILGVEFVAFLNNAYGLDEKAGVLYDHP
SLAALAAHITSRTAPQPAGAVPAGSVSAADLDALLAAVRDNRLTVEQALALLPQHT
>A0A2C9ELU6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudomonas protegens (strain DSM 19095 / LMG 27888 / CFBP 6595 / CHA0)|TrEMBL
MTTARESLIEAFMDNDVRDVSKEQLQESLAQAITTIRALKEKVAGKSSAPVEPIAIVGLG
CRLPGSADTPKRLWSLLKNATDAVGDMPSDRLYGTDYYHPDPQAPGKAYVMRGGFIEGVD
QFDPGFFGISPKEAEGMDPQQRLALEVAWEALENAAIAPDSLHGKKLGVFMGVSTNDYVR
LRQQLGAVEDVNAYQFYGETSFVAGRIAYTLGSRGPAVVLDTSCSSSLVALHQACNSLRS
RESELALAGGVNLILSPYGFILVSKLRAVAPDGRCKTFDAAADGYGRAEGCVILALKRLS
DAVRDQDPVLAVIEGSAVNNDGASSGITVPNIHAQEEVIRLALGQAGLQGSEVDYVEAHG
TGTALGDPIELHALHAVLGKQRPVDAPLLVGSIKANMGHLEPVAGVTGLAKVLLCLQQEA
LVPQVHFNTPNPRIEWDRLALKVVTESTPWPRQGKARHAGVSSFGVTGTNAHVLVGDAPL
RERAQGRDNPWQLITLSAKGETPRRQIAGRYERFIADNSQLELKDLCYTANVGRAHFGHR
FAAVADSREGLREQLAAYASRKVVGHVFEGRCQGAAAPLVMLFPGQGCQYRAMAQALYDS
EPFFKAQIDECRALLQPLMDVDLLTLVLDAGAASDSYLQQTRYAQPAIFAVEYALARLWM
HWGVAADALFGHSFGEIGAICVAGAVSLADALRMVEARGRLAQQLMTAGGAMYALGMSEA
QLLELLKDRPGSAIELAAVNSPQDVVVAGPQAEVQALAEAALASGCKVKKLAVSHAFHTA
ATEPMLEAFRQTVAQITFSEPRLPVISSVTGRVHTLSSLSSPDYWCTHTRQAVRFSEGVN
TLIAELGVKTFLEVASDAVLTPLIGRHPLADDSLVLASLRRAGDPSRDLRLAAAQLYVGG
HNLDWARLHEHDGALRQALPGYAFQRQRYWFDNASGSPLQQVTAGAVGRLLGHSVNAPTP
AFESTLDSGLLQAVGGEIRDDLALLRPDRLLAALSDELAGHLQLDTYGVSLASITPALAF
HVDDQLHLFTELKPLSGAAWEVNCSALSAAAKVAGADWQPVLSLTLEGLPAAVRGGLPDP
GHAATQDAGFVYHMQLPAEPDPHGNHLGQVLEYLGQAVPGDAPGSISGIRRWVASRSASP
RAQSLVIATSQAHPQQFDCALYDAHGQCVGSLEGLTLAAAPSEEALRGMLYQPDVLYSLD
WLERPRQRAEVPQQGRLFTLVSRSPETAAPLVEHLQRGGHRARVLCPQQLLDSARRVLAQ
DPSQALTDEGEALAADIIVLDGKDIEDAGSTTLQSLSSLQATLFHPLLEMVQALIELGPR
GGRLWLVTQGANAVGLDRDQPLQVATGPLWGLGKTLALEHPEHWRGLIDLAPDDPHWARA
LAEEVSDPDGEDKICLRPGKRYVQRLNHFSTAQLPAQAYAPCPQGSYLITGGMGGIGLAM
AQWLLDKGAGAVLITGRRPLEDVATGLERFGAAASRVSYVQADITSPQDMQRLFCGLEAS
GASLKGIFHAAGISIPQDLKDVDRDSFDQVMRPKVEGTWLLHELSLGLDLDFFVLCSSIA
SVWGSQHVASYAAANQFLDSLAWQRRAMGLSALVIDWGLWAGGSHLFDEQVLNFLTSVGL
KQIAPVQNVGLLSRILASELPQMVVSGVDWNRFKPLLESRGPQPLLQYIRSQAPTARAGD
SSNVEILQQLAGADEAAALALLDDYVWEQYAQLLGVKTEQVRAKLEDGGSLMDYGLDSLL
VMDMVARCRRDLKLEIKAREFLECPGLMWPDFLARSIKEQGCVAEA
>A0A4V3HZJ3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides salmoniphilum|TrEMBL
MLLSADVVELVAKEASAILAYALEHPHVSPDRIADMIFRTRIARRYRTLLMVRDRDELLG
ALQAVVDGTNHSCVVRGTESANAHRIGYIFPGQGGQRPGMGRAFYDAFAEYRVEADRCSA
LFEEKFGQSPLDYLLNADIPADDTARVVQPALFTQMVGLAAMWRSVGVVPDLTVGHSQGE
IAAAYVSGIMSLADAVTVVGVRAGIVDAFGADTYAMAVAAADRDTCEELLARRSGWAEVS
VINSPSLAGISGDRETIGDIVESLTARGVFARVIPVQYPAHTSGINAIGAEVSQALRDRL
GTLQFNDSEIDCVGATLGAPITAELPIDQYWFWNLRNPVRFDRAITAAAQSGADTFVELA
EHPALQLAIQENLRVAELPGRVVGTSTREGNRLDEFTLNLAQLMVHDLGYRWESLRQDTT
GHPRLPLLDFPNVQTNDITLWLPYTTTPSALTAPTAIVSQVSPSTAAPETDKTTVPARLL
REDWVRLAKRSLTPPRAFGVIDHTGECAELAAALCSAADDTGSTARIIDPNNSISEFDAI
VVLLPEHPSPTDHESVSEVTSFFGEHTWWPGRDSAVTDYWLVTVGGEAVIAGDPPPHPVH
AAASAGFRSIGAEHPGIGFRHLDLTSESAQADSAKTVVMALHTAGEPELALRNGTLYAKR
AIECDTPAPDSVGREHVLIVGGTGKLGLEFCEHFAQHGARRVTLVSRSGETESVAQRLND
IRRKTSTDVNVVSCDISDEAAVARLAEQAGDMPADLIIHSAVDYSDIDFADVTNEKVDAV
LQAKILGISHVLRTFPRTDSCRIVLCSSMAATIAGRGQTVYAAANRMLDAMAHRLRSEGL
DCVSVQWGQWAVHFELGESGAARLAATGVHPMRPAEALALGMSSLQSNAIVVAFDVAQAR
SVFSLYGYGPLLSGLQAHTGLVRPDTPERQTGAPSGDVRARMIRLLSDVIGNDRVDTIDT
TAPMVALGVDSLQALEFRRRVIDEFHYEVEVADLLGGASVDDVIASIDKTTPSAVPRTTD
SSPTAGQAKPLMLAETAPQAAERAMPQNLDIDRMRSARTDLDLFGMRATFGLIEPVLREG
AGLSADDIAQQLEFAPRHRWLLRQWLEVLTEHGHLAYDAERYRPNTPVPSPSCADIYTVC
ADLGYPRELAEFMGNCNERLADLGRDRVSIQELLFRNGDMVVVEAAHRDNLASRYLNLIA
REEVIDIVSRLHGDRSPVRILELGAGTGSTTGEVVAGLNELSTQWDYHFTDVSRFFLTAA
QGKFGKYPQIRYGLMDMNTDLAGQSYDIVIAENSLHNALDIGQTLLRLHDVVNPGGAIVL
IESCKANYQVLNSVQFLMSAAPGQPHPGESDIRRGARIFLSENEWNDQLSQAGFRPLLTL
PEASHPTHMLDQRIIVAERD
>A0A4R8SRY4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides salmoniphilum|TrEMBL
MESADHPIKTAPRFAIIGYAARFPGAANADEFWDVLREGRDAISEVPADRWDADEFFDPE
PGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRLMDPQHRLLLEMAWRAVEHSGIAPTD
LAETNAGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQGPSVAV
DTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSHAHMLAPDGKCKTFDA
AADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
DALKRAGVAPRDVGYLEAHGTGTSLGDPIEAQAAGAAYGIGREANDPLLIGSAKTNIGHL
EAAAGIAGVIKVVLSLENELLPQHRNFENPSPHIPWDRLPVEVVKEATAWERNERPRIAG
VSSFGFAGTNAHVILEEAPQQAAAPVEIETAGEPQSDVAGAAALRFSILPLSARTPAALV
QIADQYRSWLNAHPEATLADVCLTAGVARAHLEHRAALVVNSREAAVELLGAVAEDRPAT
GLGRGESYDAPKTAWLFTGQGSQYPGMARELFDTEPVFAETLKQCAAVVADVLEKPLLDV
IFDVDGPEAGETLRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAGV
FSLEDGTRLMAERGRLFGSLPAGGRMAAVFAAAERVESLTDEFPSLSVAAYNGANTVLSG
PAQDLEKAVAGLVAEGVRCDFLETSHAFHSALLDPILDEFESYAGQFNYKTPQRILIDNR
TGAALGRSTKLDGAYWRRHARQPVEFAKSVRTLADLNCKVLLEIGPQPVLTAAALRAWPD
PATAPRAIASLRRNTADHRQITEAAADAYVLGHVPNFGAFRHGHARKIDLPTYPFEHRQY
WFNDKRDADGRDTTNQQQRAAGPRTEAVRLLEDGKIEELASLLGGAGGDQQTLAVLTKLA
AQHNQQRTTQTIADDRYQFRWDKSPTPLSGAESGAGITWILVGEVSGAAAPLVEALTARG
HQHRILGLPASDADEQQLADALRAAAADASAQEQALRIVHVAALDAGSPSARSLLRIQHQ
VLAGTRRLFRAAAAAELRSPIWLLTRGAQRITDADTVAPEQSALWGFGRAAALELPQVWG
GLADLADASADEWSQFIARASASTDAAMREDQIALRDHAVYVPRLVRREELPSGKPLEVR
DNATYLVTGGLGSIGLEIAGYLAAHGAKNLVLTSRREPSESARQRIDALGAQHGCEIRVV
TADVADAHDVARLLAGVQAELPPLAGIVHAAGEISTTPLSDLDGPSQQAETDRVFAGKVW
GAWHLSEAAADLKLDFFISTSSIASVWGGFGQTAYSAANAFLDGLAWRLREQGIAGTSVN
FGPWSAGMADAESRARLEQRGIKTLSPADALAGLADVVSASSPQGVIARIDWARFLPLYQ
QAGRRAFLAELEREVPLHLAASPAVTQSGKTQLVERLASAPIQQRKKLLTDYLRDAVAEV
TRVDVSEIREDAGFFDLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLGE
VLGLNEQVKSAPRQAAVTRTDEPIAIVAVSCRFPGAPDPEAFWDLLSGGVDAIREVPEDR
YDIDEFYDPDPEVAGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEG
LERAGYSPAALRGSRTGIFAGVGANEYAHLLSSESLDKIEPYFITGNALNAISGRVAFAL
GFEGPAVAVDTACSSALVAVHQAVQALHSGDCDLAVAGGVNVLLSPVTVIAASRARMLSP
VGRCKTFDASADGYVRSEGCGILVLKRLSDAQRDEDRILAVIPGSAVNQDGASSGLTVPN
GGAQQRLIGAVLDRAGLVGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGGSRDADRPLLMG
SVKSNIGHTESASGAAGLIKVVLSLQNGVLPQSLHFDKPSPHIPWDSLSVRVVDKAIPWE
ADGRPRRAGVSSFGFTGTNAHVLIEEAPQRPTDVDEDAADAPDTAPAPQGDQVSVLPLSA
RSPEALVAVAQRYESWLTAHPDVDIEDVCLTAGRGRSHFEHRAALVVDSVGAAREGLAEL
VQNRLRPGVVRGEHTNHPTTAWLFTGQGSQYPGMARELFDAEPVFAETVTRCAEAVKDIT
ARPLLEVMFATDRETGGEAGKVLRHTSFAQPAIFAVEMGLARLWQSWGIEPDVVLGHSVG
QYAAACVAGVFSIEDGARLIAERGRLFGSLPAGGRMVAVFSDAKHVEQIAGEFPRVSIGA
YNGPNTVLSGPGEDVEQAVARFEGEGIRCTWLETSHAFHSELLDPVLDEFESYAAQVQFG
TPTLPLVCNRTGAVLTAQTPIDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVL
TGAAVQVWPEHLAAPRAIVSLRKGIGDRRQIAEALAAAYVGGHRPNFAALERHPRNTLEL
PTYPFQRRRFWPKSSGAAIEGGGGLTAGILGRGEDLASGDSVYISRLSVRSQPWLSDHVI
YGTVVVPGATYAAMALAAVGTPARAKDVFFYEPIILPEKSSREVQLTLHPLEDGSGSKFQ
VHSRPYGERDVDWSLNAEGTVVTGIGEDTDEPTPGTEEPVDAAIERMERMRPMELFEIFA
DLELAWGPTWSGSLKSLWLGQGEAIGDVLVGEELAEQLGTEPMHPVLMDLCTGVAFPAFP
ALLAAEQGINDLFLPLRYGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYLDRDGRH
LGGIREFTVKRAPREALLRGLGGDATRLLYTLGWHEVPVPPAEDAAAETSGTWLIAGFDE
LAARVPGCIPCDRTTDPELLGQVLEQAKERGVPFSGVVWRATGPGAKEGAGFSDTEIARL
ETEIANLLSAVHTVQNGSQNGVKLPHGLWIVTERAVATESGEPVDPVQASLWGFGRTTIN
EEPALRAKLVDCDGSREAVQALANLLVTPVDEPEIAVRQGKLLASRLLPWSRSGNLTVPR
GSDYALLPTERGAIDNLRIIEKDVPAPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPI
GGDFAGVVTQLGEGVTEVEVGQRVYGSMQGAFASRFNAPAQFLAPIPDGVSAVEAATIPA
AALTVRLAFDWAQLKPGDRVLIHAASGGVGLAAIQMAQQQGAEVYATASTFKRATVRKLG
VKYVYDSRTTDFADQILADTDGAGVDVVLNSLTSEGFVEATVRATAKNGRFAEIAKRDIW
TPEQMAEVRPDIAYEIVALDTVMFQEPERIRALLTEVSDGLAKGEWTPLPAEIYPLTEAR
TAFRRMQQARHIGKIVCQMPNPLAPRSDRTYLITGGLGAIGLHTAGYLAQLGAGDIVLTS
RRAPDTDAQRLIEEITERSKTRIHVFTADVGEESEVAKLLERIRAELPPLAGVAHLAGVL
DDALLGQQSVERFRTTLAPKAFGAGYLDKLTKDDELDFFIVSSSVSSLFGSPGQSNYATA
NALLDGLIAQRRAQGLPATGVNFGPWGQGGMASSAAATANISAQGLIPLDPSAALAALAE
VIANGTGQATVIKANWQRAAKVLGSSRPPILDLVLPSAIGEVTGDSELLKQLMEIPVPQR
AGFVTEFLQREVQNFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAV
FDYPTIGGLAEYLVAQLPDAESESEESLPAAESAEAPPAADSDATPTPSDAVSEPKA
>A0A0H3A3S9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium avium (strain 104)|TrEMBL
MTPMSENGFDAAGIDPVVIVGMGVEAPGGIETAEDYWELLAHGREALGPFPTDRGWAVSE
LLAGSRRSGFKQIHDRGGFLSGAATFDPEFFGISPREAVVMDPQQRVALRVAWRALENSG
INPDDLAGEDVGCFVGASATGYGPEMARFSEHSGHLLAGTALSVISGRIAYTLGLTGPAL
TVDSSCASALVAFHVAVRALQNGDCDLALAGGVNVLGSPGFFVEFSKQHALSDDGHCRPY
SAQASGTVWAEGAAMFVLQRKSAALQAGRRVVAEVRATAINQDGRSAGLSAPSGDAQVRL
FRRALGESGVKPAEVGMIEGHGTGTRLGDRTELRSLAQTYGDTEPGAGALLGSVKSNLGH
SLAAAGALGLAKVLVSAEHGAVPPTLHATEASGEIDWEHQGLRLAQTLTPWPAIDGQRTA
AASAFGIAGTNAHLIVSMPEVA
>C6WL78|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064 / NCIMB 13271 / NRRL B-12336 / IMRU 3971 / 101)|TrEMBL
MRVVRSELVIALNPVHRSAPRLTAAAARAGALAVLELPADVDGAVRALADTARWTPGRFG
VRVRPDSVVPALPEAAEVVLLADPARSPAEFADREVLVEVTDLAEARAALAAGAVGLVAR
GRESGGRVGELSTFVLLQQLLAEVRDVPVWAAGGIGPHTAAAAVAGGAAGVLLDTQLALY
DDAGLPVATTEALRGLDGSETAVHQGVHFLHRRGPGATALPEDPAALLHHDPARGLLPVG
QDVALATAFPRRWPTVAAAVRGVRDAITGAFADDAARTALLGDQSALRTAGEARAENPQG
AGTASTATTPPGDRPDARSSAEPPALQRESALGTALPVVQGPMTRVSDSPAFAAAVADAG
GLPFVALALSGADQTRALLERTRAQLGGKPWGVGILGFAAEDVRAAQLAVVEEVRPSHAI
IAGGRPAQAAALEAKGVSTFLHVPSPGLLRQFLAAGARKFVFEGAECGGHVGPRNSFPLW
ESQVDVLLEHGAGAGTAVLFAGGVHDARSAAMVAALAAPLVRAGVEVGVLMGTAYLFTAE
AVDAGAIGEVFQRHVVTATRTDLLQTAPGHATRCVASGFTGDFAALRADLARDGVPDREA
WERLERFNVGRLRVASKGVERVGDELRDVDHDRQAAEGMFMAGEVSVLRSATTTIAALHA
DVTAGSAAHLAERGESVRAATARRTAPEPKPLRVAVVGMACMFPGAPDLPSFWANVLAGR
DSVTEVPPERWDPELYYDPDGDGERTPSKWGGFLPPIGFDPLAYGIPPASLGAVEPVQLL
ALEASRRALVDAGYPHASTDHSRTSVVFGAESGSDLSGATTLRTTLPAYLGSVPPALDAQ
LPKLTEDSFPGVLANVIAGRVANRLDLGGANYTVDAACASSLTAVDVACKELVTGSSDLV
LCGGADLHNGINDFLMFASVHALSPSGRSATFDHAADGIALGEGVACVVLKRLEDAERDG
DRVYAVVDGVGSASDGRALGLTAPRPEGQRAALTRAYRAAGISPAQVGLVEAHGTGTVVG
DRTELRTLTEVFTEAGARPGSCAVGSVKSQIGHTKCAAGLAGLIKTALALHHGVTPPTLH
LTRPNPAWDRDTSPFAFHSAARPWAADPADRVAGVSAFGFGGTNFHVVLRAHDQPPARHA
LQEWPVELFLLRGNDSGAAIVERADRHPGARLRDLARFAAARADVAAGRGEPVRTAILAG
SVAELRAKIAGTDAEGVFTADAAEPGKLAFLFPGQGSQKPGMLAELLVAFPELHDHLRLG
ARWADAMYPPTAFDEETAALQRERVTDTATAQPALGVVELAATELLATFGVRPDLVAGHS
YGELAALAAAGVFTPADLLTASAARAEAILDQVRSGDPGTMVAVTAPADVVERLVDGLPV
VAANRNSPKQTVLSGPTAAIREAEERLRAAKLGTKAIPVACAFHSPLVAGAGEGFRRVLD
TMPLRAPEIPVWANRTAAPYPADADAVRAELAAQIGAPVRFAEQLEAMHDAGARVFVEVG
PGRVLRGLVRAVLGDRPHRVVTLDGGLTGFLTALAVLAVSGADVLAGPLVRGRDAVDPAD
APPVPGWTVDGHLVRRADGSIQPGALRPAHRVTAELIVPEQQAQQQTGTPDALVAEFLRT
SREMISAQRDVLLTYLGAAGVPAPVVLHQVAQPVTAAAVARPVVEQAVVAQAAVAVVRSA
PVVDVLRAVVEVVAERTGYPVEMVEPDLDLEADLSVDSIKRVEIAGELAQKLGLALDADS
GLDDLAAARTAGALADALRTRLPDAAPVAPVAVAAVVASGPDVLRTIVEVVAERTGYPVE
MVEPELDLEADLSVDSIKRAEIAGEVATRLGLDVGDGSRVEELSAARTAAAIAALITGAA
SAAIPGAATTSATPAAALTAVTAAGAPAPSTGAPAAASTGVLSAARGGAPAAAPTPAEAT
VIAPKRLVFREVPLPLPATTDLTGARVHLVGVEQLTGADREIPARLAALGATLTSTPAGA
VVVHLGALDPAEPPLPEEFPRFQAILTAGPTALLAVDRRGEGSVTGLRGFFRTLAREYPD
LPCALLESADPVAAIAAEITTPSGHPVVLHGGNSRHALELAFEDLGPVASSGAGPAGDGT
AEALAAGLDRDAVVLLVGGARGITARFAKTLAAASRCRLELVGRTPLPSGPEDPDLAAAT
DRTALRGAFLSRGMTSPAEVERAVSAALAAREVRATLAELTGLGSEARYHAVDVLDAEAL
RTTVKRVHDEHGRLDAVVHAAGVIEDKLVADKSVESFRRVFGTKVDGARTLLDAVDTLPE
PPRHAVLFGSIAAALGNRGQCDYAAANDALEELARRWSKPGRRGLTVHWGPWAAAGGGMV
TPELMRSYAARGIALIDPDEGPLSLLRELAYGADDRHAVVYTASGW
>Q3M5Z6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Trichormus variabilis (strain ATCC 29413 / PCC 7937)|TrEMBL
MSHTSDINQLSPLQRSVLALKEMRAKLDAVENAKTAPIAIIGMNCRFPGGADYPEKFWEL
LHNGVDTITEVPADRWDVDEYYNANPNTLGKIYTRYGGFIKQVDQFDPHFFGLSPLEAAS
MDPQHRLLLEVGWEAIENAGQSPEELNGSQTGVFMGLFMEDYSRFNLYSGDHHRIDAYSS
LGNARSIAIGRLAYVLGLQGPVMQLDTACSSSLLAVHLACQSLRSGECNMALAGGVNLIL
APEASIGLSRMRALAPDGRCKTFDAKADGYVRGEGCGIVVLKRLSDAIANNDNILAVVRG
SAVNHDGASSGLTVPNGLAQEKLINQALTNAKVAPEQISYVETHGTGTSLGDPIEVRALG
SVLCQGRSPEQPLLIGSVKTQLGHLESAAGVASLMKVVLALQNAEIPPHLHLQQPSPHIP
WDKLAVAVPTKPTPWPAVNGKRLAGVSSFGMSGTNAHLIIEEAPELKLELPKTERPLHLL
SLSAKTEAALLAMASRYESFLTSHPETSLADICFTANTGRSHFEHRLAVVAASNADLREQ
LTAFASQKQTSTSVSGQVQKKRSKVVFLFTGQGSQYVEMGRQLYETQPTFRKTLDRCDEI
LRPYLQQPLLSVLYPTSDVTSPLNETAYTQPALFALEYSLAEMWKSWGIVPDAVMGHSVG
EYVAACVAGVFSLEDGLKLIAERGRLIQSLPQNGMMAAVFTNEARMNGILAAYTGQVAIA
GINGPENIVISGAREAVQSVLKELATQGINAQPLQVSHAFHSPLMASILDPFEQIASSVQ
FQAPRIPLISNLTGQILKPNEIPHAAYWRQHLREGVRFYAGIKTLHEQGYEIFVEMGPST
TLVGMGKRCLPEGAGTWLTSLKKGQPDWSQLLASLSELYIRGIKINWTAFDQGYQRRRLA
LPTYPFQRQRYWVENLSPNLSPTRREALNSPPSLQGKGAGGLGFTSAIPPKALPKIPLSV
PSNWFHSWQWTPEVLSQSQDIPSGAILIFSDRHQVGENLAKLFDAKKYTTYFVTPGESFT
QTAGHFTINPASVADYEQLIQNIKAQGVTVTAAVHLWNYSLWATSPEQLLENDRLLNERV
YSLLFLTQALVKHYPASPLNFLVVTQGAYPISPNDSLHGVHQSMAGVLAQVVAQENPQIQ
AKVVDFNQDVYLPEKLADILFQEMKATPTGEGIVAIRDGQRLSRTLAKINVPTENNSLPL
SAGETWLITGGTSAVGTEIALAMVRQVPINLVLTGRHPLPPKQEWQSASHDASTQQRIQA
IQQLEQLGATVMYQAVDVTDALGMKQLIESIKSRFGNLDGVIHAAGAVDHSTFKLLQKQP
ASVTKVLAPKVQGTIILDTVTRNEPLKYFVLLSSVSASKAEWGTGMGDYAAANTFLDSYA
IYRTQHGGQGRSLALNYSLWSDRGMGALLGASTLLMVRSKGLNPLEPEPAANAFIQALSL
DASPVIHIIDLIAQATPEIAPKSSASQSQAKPRNLRQLVREVLLQHLRIPEAQVEGHKTF
QEMGLDSVGTVEVVQHLGTTLGEELFPTLLFEYQTPDDLVDYLQSKYGYSVKTSTSAMDY
APPLVIAPEETSSPQTEKSAPPNVAPQEKYQDVPEQDIAIIGMACKIPGADNLEQYWDLL
NAGRSVIQDVPQDRWFNQHYFEAKGNSPQAKISKRGCFVNSPFDFDPMFFGISPKEATAM
DPQQRLFLELSMQALQQAGYGGKYRPDNIGVFVGCGQNTYIEHFTNYQYYEELRQRLQES
SWFDHLPAEDRQHLLKTLSQVLQPSEILPESAAGNEVNELAARVSHCLNLKGPSMAVSTA
CSSSLVALHIACESLRSGQTGMAIVGGVNLNLSPSPFTFLRKAQALSLSGTCYPFDRRAN
GIVLGEGAGVLIIKPLKQALADGDLIHAVIKGSAVNNDGHSQGITAPNPKGQAEAIRQAY
NSCGVDPRTISYIETHGTGTLLGDPVEVEGMTKAFRSFTDEKGFCTIGSVKSSIGHLLSA
SGIVSLIKVVLAMQHGKIPQTVGFEEPNPHINFADTPFTVAGKSIPWSPNGNPLRAGVNG
FGFGGTNCHVILEESPVAANLQSQVTSSAPDLLCLTARNQQALQEVARQLRQHIIHHPEQ
ESSQICFTQNNAQKELPYKAALVVNDRQHLLNYLEAICSAQTPADIYTGRANPQRTTPFH
LILDGTSAIAPAEIETLGQRFPQFQVAYNSVRAGFHEMSEQAHIFAVQYAWGRLLMSLEL
QPTSLLVEKTGILAGATLRGMLTLEQAIALLLQIEGEKGLSVHDVSAKEQSASTWTCPLV
TSQGIFSHADTISTDQLLALVQVSEQLNVDVCQDVISKESVYLHLGDSFALKEQLASLDE
LGVWIYLNKRQPVVERVLTSLARSYVAGIRFNSIPLFPQGLRRVLLPTYPFERKTYRVSL
VDHTQENQATSIPAAELLPPRPESKHQLTVAQTRLLPIEQLSPLTDNQRQSSYAKLTEDL
KIVDNRQQPRLVPMEQLSPLTDSQRQSSYAKLIEDLKIVDNRQQPRHPVAVTQNRLLPME
QLSPLTDSQRQSSYIKLAQDLQKFGKSVIGH
>A0A655AXT8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MKVILAAQHAAIPPTLHVDEPSREIDWEKQGLRLADKLTPWRAVDGWRTAAVSAFGMSGT
NSHVIVSMPDTVSAPERGPECGEV
>A0A5S9MQ96|6-deoxyerythronolide-B synthase|EC 2.3.1.94|BD1-7 clade bacterium|TrEMBL
MAKISIETCLNKLASETPDRALIVFPNDWRGKDVSVTCKELNTSVTAIASELQCIVEPGE
SVIVNGPLDLRAFESILACWLAGTICIPFIERLDPLSLIDKVKKTGASMVLSSSEAEEHH
ISSLLVQNDLYDTCACLSVDGMRDNNKNAVLDSSRQDSAAMGFYSFQKGALTHYPLSFIT
ELMDDWIGLIGIDSESVISSSMEYGILAQLTTSLLCPVFSGATSIVLTSHLLSVPAAAWL
HALVDYKVTAALASTKFLHEAMTVSAEELDLSSVKTFCCDERAEPSGLLAAFYGRFLDAN
WSPATICIVCRENGDIIRDPEKSLIMTKPQCTPPAMLISADSKAYLGKRASAISRFLERT
SYSLEQVAGATQRGSEDRDVRAALVSPNPEQVCGEFMSALEAVADHQPHPWAVQGIAKKP
GKTVFVFPGQGCQWQGMANQLLEKEPVFSRAIDACDEAFSKHIDWSIRAVLLGREEGRSL
DQVEVVKPVLFSMYVALARVWQNCGVMPDAVVGHSLGEVAAAHVAGILSIEEAAEVVAKR
SQILKQLGDDYGLTLVKSSSADIENNILPQFSDLSLAIENGPDEVVVGGCCHDLERLEAQ
LKQQSVFCRRVDISYASHTRHVAKVKHQLLGIFDNIVPQPGYAAFYSGYEGRRLSANRLS
AEYWYGTERYPVRFRRTVEALIRDGFTTFIGVSPHPILFGAVQSVADNLGEEVIYSGTLK
RDTDSYLQFRLNLANLWVQGYPIKWRRCWDPNHYDIGLQQYLTVNARHVRRRDSRVEKDQ
PLATPVLIEIVRELILKTLGDESMHLPDDLPFKELGIDSVTAVDISKILSWKFGLNLPPT
MLFDYPSVEKLVAGIADYLFGGDPDNIVGACESEGDKYAREPVAIVGMACRLPGGVDTPD
ALWDILSEERDVIADIPPERWDVSAMYDEEKGLSGKTYCRRGGYVSDVDLFDAEFFGINA
REAKNLDPQQRLLLEMVWESLERANILPETLMDTKTGVFVGLXLSDYSLLDTKNLSLQDG
YRTTGYYLSTASGRISYTLGLKGPSMTIDTACSASLVAIHQACKSLQIGESDMAFAGGVS
LILAPNILVEFSQLGASAPDGRSKAFSDSADGAGWSEGGGILMLKRLSDAERDDDQVLAL
IRGTAVNQDGRSSGLTAPSGPSQQQVVRQAMANAGLTINDIDYIEAHGTGTPLGDPIEAE
ALSAVFRRREAPLWLGSAKSNLGHTMAGAGVTGLIKTVLMMQNETIVKTLYSESPSQKIN
WSNSPLQLAQTSIAWPKGKPRRAGVSSFGISGTNSHAIIESYDANTADRDDPAIHQTPLE
DYLVFPVSGKNTQALRAQAAHYATYLQSHPDETLFDVAAGLSLFRSAFDHRCAVVIPADK
RQLLVQCLQSVADGQSHPAIVGPLAVRRSRKLCFVYPGQGSQWLGMGCKLMNNRIFAAEM
ATCEKALSAYVDWSLVDVLQGIEQEHTLANTDVVQLSLFSVFASLTALWKSLGVEPDVVI
GHSQGEVAAAHAAGILSLDEAIRIIIARTRAISKIAGSSGMTMVKASDEVVQDWLVSQQS
RLSIATVNAPGEVVVAGYLDDLDAFEKWLSDNGTFWRRINVDYASHSECVDGLTDEILSA
IGTVQPQASDIIFCSAVLGKPVAASELDAAYWADNLRRPVKFMDAVSEVLASGYSNFLEI
SAHPVLHQALYAIAEAAEKDIVVSHSLKRDTDDRETIAKSLGYLFCCGIDVDFAWFYPNV
RRRPDLPTYAFQKKSHWLDISHKDVKGAGQLDTGHPVLGLYQATAHGGVFICQLGDEVQR
WLHDHSVHSVGLMPAAGFIDLMKAAADFYFSAVGHTDNGVLADIEFVAPLLLDRPPKHLQ
ITISQPSADGICAIAVASSDDSMASAWDEHCRARVVNSIQSQEIPAWQPEGEVVSVNDLS
ERMSLLGIWDGDSMQGLRDIRIEGNRAWGRVVLPAEVDIDGFSVHPGLLGAAMQLNNLLL
PVRDGLYMPVAANEICWIGHQVREILVCVESTGDVSDAVARFNLSCLSPDGSWLGYIHGL
TLQFVATTHLIQLFNRGELPPHSLFDVDWQNTVLGHIDQATNLVRCEYDVSTDVDHRCVL
DITTDAELLVVSWPIPQSLEDVQSLLHHGLRLLQDHVSEHQNLKVIWVTQGAFQPLVQNA
SDAPYTSSIRGIWGFARGALAEHPELQLWLVDVSTGHKLNAEEYAGILTDTRREWRHVDG
AWQVPQLRGLNGKVLEIPPLRSDGTVVITGGFGALARHAAQWLVTEHGIRQVSLLSRRGA
DTELRQQFIQELDAQGCAVDIIGCDIGNCSELRRQLAELHKNTPIRAVIHTAVSLADNWL
TDMQASDIDSVMYAKVLGAWNIHQVTQDLQIELDQFILYSTVTGWFGGEGIANYCAANQC
LDALAEYRRAIGLSAMAVGWGYWADTSSDMLAHFTEADHARFRQPGFIPIDDATGVRLLD
AVLALNVANPIAAPLEPDALGQFYRGRHGVIQSLMEDTQERHQERDAFDQLDPDQQRRLI
ENWVTESVVAVLGLESASLDVNLPLASMGMDSMIAVEIRNRLVRQTGLTLPANTLFDYPT
VSMLQAYIAKRLQNGAQSTVSAPEVHAVAKPKDIAIIGASCRLPGNVDGLESLWKLLDCG
GDAIAEIPKERWDIDALYDPDPDAPGALYFRDAGLLKNIDMFDAGFFNISKHEADSLDPQ
QRIVLELAWEALEDAGIVPESIDNSDTGVYLGASYSGYDYMGAQRLEDAGAYSATGSLSS
TLSGRVSYFLGLHGPSMTIDTACSSSLVSLHEACQALRSGTTNLVIGGGVSVMATPRLLV
YLSRLRASSPDGRCKAFADDADGAGWAEGAGVVILKRLEDARRDGDRILAVIKGSAVNQD
GRSAGLTAPNGPSQQAVVRAALDDAGLGIDDIDYIEAHGTGTALGDPIEVGALSEVFAAR
DKPLYLGTVKSNIGHTMPAAGIAGVIKVVAALKHKQIPATLHADSPTQKIAWDATPLSLV
NQSMSWMPDHPRCAGISSFGISGTNAHIIVQEAPQPAPQNDAEYVADSPSPLGDWVVLPV
SAQSSDALMAQAAQLGEYVKSQASYDSASIALGMGQYRSAMRHRGAVVVSAASDESLDSV
MGALAANNPGDLSDCYVEQGIAQTGIRQAFLFPGQGNQWMGMGAGLLDVPAFSETMAACE
AVFKPLVGWSLTEVLMGKDATHSLGDVDVVQPVLFSIYVSLAALWRSFGVAPDAVIGHSQ
GEVAAACVAGILTLDDAALIVSARSQAVKRLSGTGSMTLIKQPAEENLALIEKHQLKLTQ
AVVNAPGELVVAGPIDALDLLEEKLTEMGVFWRRVKVDYASHHEHIDAVRNEILEAISGI
NPMDGDIAFYSSCKAQQLGGQSLNAEYWFENLRQSVRFQSAIEVMLNDGFGRFIEISGHP
LLTQALELISESSETRLALVHTLERDLDDKRRMAQALAKYFCSGGQLNWRSLYPGQSRPD
ALPTYAFQRQRYWVDESADLIAGAGQIDTRHPMLGYYQSTPAAHLFFNHLSLKTFPWLAQ
HKIVGLPLLPWAALVELSVAAVTYLLPDCGGIVLTDFSLAAPLVMTDDGADVQIAVADDE
SRRQISIHARGRDDSGWTLLSQCNWDIDSSIGSADTLSPISHLPSQDLPSWYDGLTERGL
DYGAVFQGMTAARTDGKAWFTDVHVQDSEETSDASAYWLHPALLDAALQAAILAVGASDQ
LIQPVAASRITILPARYNALRVKATLADNATADMPLIELGLFDSEGQPVGAIQQFQTKLL
SSERMRRSIGGQSDRHWLQSSFMAYTTTELDNLPVHSHGTVEHMHLASIESVDALISKLR
QFGEDDIMCIHVAPVDDMAKAQASLQRTLVILRKYVVAELSAALVFDVSGVMGADKSATP
SILLKGLGSLIRGLLSEMPTARVYLVDRPYEISLTDQDVRRAIALNEPELLFDGSLWQGL
RLQNLPTSADEQPSTEKASSAWRTDGTYLISGGLGALGRHALQWLATERGIKDVVLVSRQ
GRASGQYPAIQELCDELDIHADVVACDISDKQQLQQVLDSLQKPLRGVIHTAAALSDRLL
ADVELADFDTVFNAKVNGAWHLHCLTQTCDLDAFILYSSFAAVLPAPGQAIYAAANRTLE
AIGQYRRSLGLPAHVINWGYWEDKRSSLTGNLSANVIAQMEDTGLVPITHALGDLLLDAT
LAADRDVSIATCMDLKRMEKHFGEYLPSVLTSLITPKAHSQGRFIDRLLNLPAEQQPKAI
ESRLVEHFSEVLGLNVLDVDVDRSFQELGLDSLTAVHIRNRLCRDLDRSLPANLLFNYPN
ITELKTYLVEVVLSEASADVVVQDDVLDDLQHYLKHCLNRLPSAAGDDSQKSVLQRMEHM
LNEYVQAQKSESEGVSYRAVSIDEISDDEAMRLLKRRLEDRK
>A0A068QUF5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Xenorhabdus doucetiae|TrEMBL
MVNNVTGLEVAIVGMAGQFPGADNVHDFWEMLCDGKEGISRFAQEILENNGISSDEYLNE
NYVPAKGIINKPYHFAADYFAINHPDAEKMDPQTRLMIETCWQALNHAGIDVKDYPGEIG
VYAGAGNQWSWFKTLNTEFNSSAEQFHVATLNDSAFCSRISYLLNLRGPSVTIQTACSTS
LVAVHTACQALQAGECDIALAGGVSVTHPHQAGYIYQEGMINSIDGKTRAFDEHAGGTVF
SNGVGVVTLKRLTDAIEDNDRIYAVIKGSAINNDGNDKISFTAPSALGQEKVIRAALDVS
EIDPASISYIETHGTGTVLGDPIEIAALDAVFHGQQSCAIGSVKSNVGHCDTAAGVISLI
KLSLCIYFKTLVPSINFEKANKKLELEKTPFHVNTQTKLWVTKNNAPINAGVSAFGVGGT
NAHLVLQEFSGKTEPILAEHLNYKELPNRIEFKPSIKKDTSPVFNEEQEVDVDFAEKIDI
NSILKEILSILKAYFTNKKISKDDNFFDVGASSLDIVQLHEKINSNYAIKLSINDLYRYT
TCQKLSEKVYDVINETPRKTTRKLKTGASKKTPVRIKTALHDYPENAVAVVGISGRFPGS
HNVQEYWKNILSGKEGISFFTDDELIDAGIPEHIFKNKHYVRAKGIVENALNFDKTAFGY
TMREAQYMDPQFRLLHEITWEVLDDAGYGNPKYRPVTGLFASSGSNYEWLDRVKEEVKDT
TEQFSIGLLNDREFLTTRIAYKLNLTGPAVTVQSACSSSALAITLACQSLRVNQCDLALA
GGVSVTVPVKSGYMYVNGMVNSADGHCKPFSENASGTVFSDGIGMVALKRLEDAIENNDH
IYGVIAGYGVNNDGYEKAGFTAPSANGQAACIKQSLAMAGISANDVGYLEAHGTATLVGD
DIELEGVKSALSVTGEDPSICYIGSVKSNLGHTDSAAGVAGFIKTLLTVKHKKIPPTCHT
EKDDHVLLEGTRFRLINTATDWGNNNDIRTAGLSSFGIGGTNVHITIQSILDQISSERDS
PELITLSSKSREGLIKTAETLGHFLNEDTHTNSLSDIAYTLQIGRGEHEYRTSFVVDNVE
ELKNALLNVKETNKIAEISFDQTPGIVFMFPGQGAQYINMARDLYNELGIFRKLLDECHE
YLFERFGINLLALLYDEKNQDSVEKLRNTQFTQPIIFAISYSLAKSLEALGVEAKAMIGH
SIGEYVAAAMAGVMTLDEALDLVAVRGLIMQECEPGAMLSVSAGREEIEPYLTDEVTLAT
VNSSTACVIAGPQAEVEKVQLALADKNYRTRLLETSHAFHTSMMKPAVEKFKEALRQIKW
KKPNKAYISNVTGQWITAKQANSIDYWVAHLCGTVEFHQGIMTCLEQPDLNAFIEVGPGR
TLSTFVKQVVGINTDISVINVMRHPLEEENDRAYLLKLFGQLWMKGYAINWSVIYQDVNP
RRVSLPGYQFTSEEMGPGNSQVSSNHAEKISETRIQKNNISDWLYGEIWQDALLPDKSNQ
SEVKTALCFVPSMEWCEPLSRHLNVDEKSIRFMLSGDDYTSVNNVITLAAGEVRHFEKLF
HELKENQLQPDSVIFAWPLSGHRDLKNTWFSAITLLQAWATVGNMGDFRLLLVNTEQPES
GMLKGLVKVITQEVSKCHPRLVQINTTESIENTCEILTEELLATDGRFIVCRTDGRCSEQ
VYERLNVEPQKKNSLLKQQGTYLITGGLGDLGLLFAEYLLKEYQATVILSGRRELPDRHE
WQQATQSDFSTTNLLQQLNKLADLGKGNVVYYPANVADKSAMQHLLQTIDEQHGVLNGII
CAAGVTEGDSFQGINRITLDACSPQIETKVEAYKILAELTEYQPLDFCLLCSSIASMLGG
LSFSAYSSVSAFADEFARQQNQKGKPWISINWDGWVFERNDSGDALGSSLSQLLIEPDEG
IQILERVLQSPLRGQIIVSTGDLNQRFEQWVGSHLKTFDINKISKSQRKTISKDQIVETI
LSVWKNFLKITQINSEDNFFELGANSLDLVQVNKRLTDALDIDISVVDMFSYPTSELLAD
YITRQYGVVSANDTQHEQPDNSDESDYVAEYVVKPDTVFDKHIAIVGMAGKFPGAEDIYE
FWDNLCYGKESISIMSKEELIESGIGSDLLDDPNYVRAKGIMPHSGEFDAEFFGYTPYEA
RQMDPQVRAMHICSWQALQDAGISPKNNKLKIGLYTAASGNLPWLAQAMATAEGSAGQYS
AMVVADKDYMSTSVSYKLNLSGPSMVISTACSSSLVAVNEAIKSLRTGECDVAMAGGVSI
TLPIKAGYLFEEGMIYSKDGKCRPFDIQANGTVFSDGVGVVVLKPLKQAIADKDNIYATI
IGSAINNDGGMKVGYTAPSTKGQVDVIQAALRDANVSSESINFVETHGTGTNLGDPIEFN
ALKQAFSTDKKNYCKIGSVKSNIGHLNFASGVTGLIKAALSIKNKVLPPTIHFARPNKEM
DIANSPFMVNNQYTELYNSKHPIRAGVSSFGLGGTNVHLVLEEYRADQNKLSGQNTNNRL
PLILSAPDEKSLQSYKKQLMQVIQSDNQKLSISDFTYSLMQRETMASQFIAVVNNRDELI
NALSSTEKDNINLLHGIKRKVVFLFPGQGSQYIAMGQDLYKHNALFRQWCDKGFVIAKEY
CTTDLKALLINGSQEHLIYETEFVQPLLFIIEYALAQVLKSYDIIPHAMIGHSLGEYVAA
TLAGVFSYEDAIKIICIRGRYMQSTEAAAMLSVMASSDKVKEILPEHLDIALDNSSELCV
VAGADEEMTQFEEICHTESIKTKRLEIKRAFHTRYMDPILEEYGQALKNITLNKPQIDFI
SNMTGEWVDNKHVTESDYWVNHIRQPVRFRQSIATALENEHCLFIEVGPGRGLSTLVQNH
SDYNTNHACLSWQGHKTKGMSLHNELIEKLAMISLYGIRVNWQQEINEQKPELIHLPPTP
IRGKEYPTDIKRLQALFSGNSPSVVEETEKEEKINTSLINQVREQDSAIDQLGAIWKLIL
GIDKVENSDDFISLGGSSLSAVQVIAKAKEINLPININMLLSGKTLLEINQLLGHENNTE
SKAKRWTFNEKFSPELYPEYASCLYSAVREKLKHEHQLDCSDALMLVSDGSPLLGIVLQQ
RENETKLSHQEVNFGSILGWPALDENYSFSYAKKFFDDYESYRNYCEKELSLGHVVIVTG
SDYYLPFSPSYGLSEAEYIERPLFQDIVLDDEVIPHAFVLVGKTDLGYQVYDGSFQYFGE
ITEQEFEKTVIGFRGLDFMQSHEVFKKSRPYLVITVNCDGDFPDSEEQQKIILKNLINDF
RKEEEIKYHENEFSCYIGLAAIEKLIEIPALLTNSSMTDLEEIFVRWRDQISSLKRFLII
AKSASAIQLESSFSFIQEKMEDLIVSCKDHDNDGNRVDCLIQLKSELDSVINVISE
>A0A125YWR8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii (strain ATCC 50853 / GT1)|TrEMBL
MMTRLPLCQQQAPPSLAGCHMLAAFQDIPERPLNRDLKELWAAYGENPFGNVLECWNRSI
PDEDAVVWLNSDGEISETTTFSELFSRITRLSSFLRAAGLQVGDRIILCYPPGTDFVTAF
FACITSGFVAVPVYPPDPSKGLSDVPRFCDINEIAGCKTALTNSLYKRVVQVITTVAKDS
RWRSVHWVCTDDVIKRHAEEAKNSVGPDFPNLSPHHPAFLQFTSGSTGNPKGVIVTHGSL
LHNCHLCWSAYQFPSHYENDGDDENITNHDFALVNQREFWRRRQEISIKSRGHRLRAFSW
LPVYHDMGLIGFVCSPILCGATLYQMSPIDFIRRPWLWLQGMSKYDCICCAAPNFAFEVV
TRKMPDNVYEHLDLSRVCGFLSGAEPIRASTIDRFCEKFGPKGVRRCAVCPAYGLAESTL
IVTARKTFQTVPKLLIVDSFQLQHEKTVVALKPEATVTMDSEEYQVLVGCGVPLEGVQVR
IVDPETKKELPPGKVGEIVVYSSSVARGYFGRPDTTKETFCYSFTDLQGKQTPPLGMRTG
DGGFMYEGELFVAARLKDLIIIRGRNFYPQDIEEAVDKVAMVRPGSSAAFAIEVDGHEAL
AVAAEVRLEEGIKGLWLRVKRQFDRSHYEQIVRDISKSVAANTGLTIHRIWLLRPRTIPK
TSSGKVRRSLTKEKLVSGKLEGILLDHAHHQHQAFYHDGPGGSRSRTRTGSGATPSGGAA
TRDGTASSNPSGDAHPKNSNTSNSITDSSHSVQRGSLRGDACVAGGRLGPSASHGGVHHE
KDHKHRGDGSGMSSPDQVPGAGAAASESSAHVALTEKVKQTVFEAAKTVLGSSEIPEIDA
PLHELGVDSIGAVEFSELISAELQVDVEPTLLFNYPTLSDVIDFFVRELEGKGSEDLAVS
LEKTGARETTTAIIGAACNLPGGTTSLNAFWDLLMCGVDAIAEVPRSRWDVEEYFDPDPG
ADGKAYVREGGFIEDAEMFDAAFFRISPSEAKSMDPQQRLLLEVAYESLYDSGYTREGLQ
RASVGVFVGCCSNDWYQVCSQLELGISSYTTTSYAPSIIANRLSYTFGLLGPSMTIDTAC
SSSLVALHIAAQELQGGSCMSAVVAGVNLMLSPHITVAFCKSRMLAPDARCKTFDASANG
YVRGEGLGSIVMKRLSQAEKDDDRILCILRGTAVNHGGRSASLTAPSGPSQQRVIRTALR
QAELTPGDIYFVETHGTGTSLGDPIEVGALKSVFGASRDAKTKPLILGAAKTNIGHLEGA
AGIAGVLKAMLALRYKHIPPNLHFKQMNPHIDVREFNVVVPTAPMAFPREDGGRLFAGVS
SFGFGGANGHVILQEALQQPSGDKPPCKRHSKRSIICFMFTGEGYEVSCMGRHLYETDDV
FKEIITKCNDILKRWLNVSLLSILYPPADKKMEMDKMMCQARFGHTALFAFEYALAESMV
SKGVKPDVVFGVGLGELVAAAFSGVMSLEEALYVVTQRAKLIDNLPPFEGVMVACRVSEQ
EVEMALSEMEINSRQSISIAAVYGRKNLILSGEQSEIDNVLMKLNIAGRWKYLPVHNVLT
MNLVSDIIPPFTHLMSTVKLCRPKVRLVSSTTGEFVDKEALSGRFWSRQVSQTVQLQQAV
GNIVASGCSLFVEIGPQVVLTKLAQQSLNGNAKDVTWVPAYDTTSDDVRVFENAVMTCNE
AIKIIGKERSLEEGQHGQEELIFHRKPFPWTEIPHPFLSGHKFTEKDDVVFENAFPRRAI
PLIADHAVNGTAMMPGAGMLEMVGAAALALDLRTTSGAVSLENISFERPMLIGAHRVTYE
YNRRHSLGEGGGAGTSPRTVRTPRLVNHAYTRLGFREKSAEKAISETAGPASTEGGRTPV
AGHHHGSYTKAGVLEDIKDYAHNVLRRAAQHAEEIDVHTPVPPSMAPPSIVARHPREGSY
GSMSRTSGIMGSNDRGDGLTVPLSVEMAIRCRVTKMKEVELSTVWDDEVTDHCFATIVIA
DKKQETYSSLQEVRCRCTERMDVNEYYDMLYDAGLQYGPRFRTIQELYRGEKEALARVHF
VGNVKQDPFESGFLIHPAVLDGALQAAGCLLEQSHSGNKVMVPVSVGSATLTKVEVFQPC
WAHVRLEETKSKAATLNVTIYDEVTREVVASLQNAVLRQVDPSASVVATIPKDLLWKVNW
QLVVEGDKEVVGRTPKVLFIGGNIELSEALENAMGSTCKTLSVDALPREKAELQKVLDAE
QWQAIVYVEAVTAGVYDALDVMNAAVRLVQAHYLNLNSGKAVGALWFVTRDTVFRDNGAD
KPGVEIPAHAGLWGLAKAARLEMEVSAGSPISMGCLDVSGADVSSMAQQILHALKSKVLT
MRETEVAVREDGLYVSRLAPQTEVDVRGAIEFHMPERGAISNLVLRPQAFASRLPPEDGQ
IELRVRAVGLNFRDVLNVMGLYPGDPGPPGADCAGVVVAVGDNVEHIEVGDCVFGVAQGC
LRTYVTTDSQLLRRMPESMTFEQAAALPVVATTVEYALHDLAKVKAGDKVLIHAVTGGVG
LVAVQLCKRVGATVYGTCSGGKKDAFAKSMGVQYVSSSRDAKAFAEDMRTFLGEDGKVDV
VLNCLIDDFIPESLKLLGPYGRFMELGKRGVWSKEKVAAERPDVQYELIAVDEMMEKDPI
WFGGMLVRVRGLVAEQKIQPLPMHVFDLADTGENGGVAAFRFMQRAQHMGKVVLKIPSPV
EEASKNGSIVITGGLGALGMVVAGWLAEEGARHICLLSRREEAPQPGEIPGWDWLRTINC
DVQFFSCDVSKYDSIRSVLRTIQTSVAPITGIIHTAGALADALLDSQTPELMKKVYNGKV
QGAWNLNRALEELGLNEQLKLCVFFSSVTSLFGNFGQANYCSANACLDALAQWRRAKGLC
CQSIQWGPWIEQGMAAELKQQVERNGMKGISNEVGLRVLHDAIRQQEKATPVIGCQAIKW
KLFMHRYIEQPPFFTNIEMDLQVTSHDSNTVLRNLPPSERRDYIKAQVAAAARQVLGSSS
PPPFDTPLQDVGVDSLGAVEFRNVLSKKLGVKLSATTLFDYPTLNAIIDHLCEVFGESSQ
KDNLSTKLGALSENDLVQEGMAIVSMSCRLPGNSTCPDLFWDMLMRCTDCVCDIPLTRWN
AEEVYSEDPDLPGKCYTRRGAFIENAEYFDNSFFGISPSEVKHMDPQQRLLLEVAYEAFA
GAGLTKEKLLGANIGVFVGACNHDWTYLIQEDKISAYTGTGSAGSVIANRVSYCLGLRGP
SVPVDTACSSSLVAADFAFEKLMLRDCTMALVTGVNLMLTPHLFIAFSKARMLSPDCKCK
TFDASADGYVRGEGAGAVLMLPYADAKAKQMTIQAVVKGTACNHVGRSASLTAPNGPSQA
EVIRMALRRAGMKPNDLKFMESHGTGTSLGDPIEVNAVRTVFAPGREKTKPLLIGAVKTN
IGHLEGSSGIAGLIKACLVLSRREIPPNLHFKTLNPHINIEDFPVQFVTDFVSLDSVEST
RKKNTAGVSSFGFGGVNAHVLLEEATRDQNATRKEENRPKICFMFTGQGSQYVGMGRHLY
EKEPVFREAITRCVEIAKEYLPLPLLSVIYPSPDERDKMQEAINETLYSQPAVFVISYAL
LELWKSRGVEPDMVMGHSLGEYIAAVCSGVISIQDGLKLVLKRAQIMSRAPSRNGVMVAC
RATAEQVEEAIHTLFGDGEKNVALASVNGLKSVIVSGNQQDVQAVLRQLGAASRAKMLRV
SHAFHSPLVKDTVAPFKRVLETVRLSKPRVMFVSTVTGKVARDELQNTNYWAEHITKVVR
FCDAVQACIAQGAKIMVEVGPRPTLSNMGKGCLPQTTADEVQWINSLEPETLSSAVFDSL
SALAKAGSGAMPAVFDRKFFPWTETCHPLLGGKNTRPDGSVVYSALLRDLVKALFLDHVV
YGKALLPATCLIEMMASATTHMISNHDEEKLVALSQVVFEKPLLVPDETSLSVLVTVETR
GQVRVASQVSNSEEEAEDHAVCQVNIVDALPAAPALTEIRARCKTEIEASQLYAQLHNVG
LQYGPRFQTIVKVFKGEDEVLGLLQAQNVTNFETGFMMHPAVLDGALQLSAVLAFEKGSS
RAMVPFGVDTVLLKSCPPDKELWARVVMNRKGVSSASATVHLYDFDGEPIAVLMGVTLRP
IEFNTAADIPRELLWEVEWESAGSYSMPQDGSLATPSGTDDSGAEDVTRTPSPLVTGENE
NTPSREVPSALPGLSTETPRASKPLSTDETSGAVLNKSVHSVLLVDYAGGHREVVASIRD
TCDVEVEVLSKPGSPELYAQQLRQFAEVVATKTETVPLSTILFLALDEATPAEQLAGGLL
ETVKVFAVEKFKKLPCIWVLTSGAQGPTRSVVSPKHAGLWGLMRTVRLELEMQIGKMVRF
GCVDLDKNLEVSVALHFILQKRTEEPFEAEMILRCPSEDSEKEPGTAEVVNRRERSASFV
SVGPEPVVPSTTDASAKSSVTSDRMALTPGALSCFDETANSTEKLIFNAFCPRLHRSPIP
VRGAVELHMPERGAISNLVLRPQAFASRTAPQSHECEIRVRAIGLNFRDVLNVMGLYPGD
PGPPGADCAGTVVAVGSGVRHLKVGDSVYGIAQGCLRTYVTTNGNLMRRMPESLTFEQSA
ALPVVAATVEYALHDLAKVKEGDKVLIHAVTGGVGLAALQFCKRVGATVYGTCSGGKKAA
YAKSLGVKYLTSSRDASAFAEDMREFLGEEEKIDVVLNSLIDNFIPESVKLLAPGGRFME
LGKRGIWTKAQMAAERPDVYYETIAVDTMMQEDTVWFGGMLDRIRDHVDSGNIPPLPLHV
FEMTDPLAGGVAAFRFMQRAQHIGKVVIRIASDLEVKIPSTTEPAATETAMLAEAGTQGN
ASIGTSTQQIADRTYLITGGMGGLGLVVAQWLVEEGARHIVLLSRRGEPSDTVKQSSIWE
YLTEKERTCVSVLPLKCDVSVKDDIVSAVKEIEARGFPPIRGIFHAAGVTADASLANQTR
EAIEQVYLPKVTGAWNLHEVCESMGLDKNLDMFVMFSSVAALLGNFGQANYSAANACLDA
LAEYRRARGLCAQSIQWGPWIEQGMAADLRQALDKVGMRGISNELGTRVLSEVVRNPRRA
TTVLCQSVIWKKFLQRYERVPPLFKNTRAGQGATADSSLMLRTMTAEERRAYVEKTVREV
VKQALGLADSPPMDLPMQELGIDSIGAVELRNALSSRLGVKMPATAMFDYPTLDAMVDYI
NSTLAEQCAGTEQDVSAETQMNLVPQIMHRLEGNIAVTSVAVHLPGSVHNAEEFWDMMHQ
MRDCITEVPLTRWNMYTFFDPDPDTLDTSYAKLGGFIEDADMFDNTCFNISPAEVRVMDP
QQRIILEVAYEAMVSAGYTSSGQASQQSIGCFIGCCNADWHMLDVPSGPFTGTGSSTSII
SNRISYTLGLRGPSLTVDTACSSSLVAMDNAMCKIIEGSCSAALVGGVNLMLSPHLFICF
SKARMLSPDCRCRTFDHRANGYARGEGAGAVFLKPLQAARKDDSTILAVVRGSAINHDGR
SASLTAPNGPAQQAVIRAALQSGGVKPADITVLESHGTGTQLGDPIEVGAIKAVFMHHRG
ADNPIYIGALKTNIGHLEGAAGIASFIKLVLCLRRRELPANLHFQQLNPHIDMTDFSAVF
PKATVDLPVTRKLFAGVSSFGFGGANAHVVIEEHFELSNAAEAPQKQTAPVKRERRSFPW
YQAFHPMLGHETKTEVDERKIDMEIRRDVFDLLAQHMVEGRPVMPAACYLETLTSAACTS
EFLHPCSRKMLRPNHHAAVTLEDIEFQRPMILEAPEGHGHQIFQILTASLGPNGNASISS
LKTGDEEQFIHATCRLSSVNDTTAFTRTPEENLKFLDEDTNRVPVDVGEMYEKLWKNGLM
LGPQFRTIHSIECSPRTAKVKLQLPQTPTSCELGFRMHPCVLDGTFQTVGPLVLAHDEQA
RKDGSSSNVGTMKLMIPFMIQRITLTSMHGVSNALWAHVALVKRESNQAIVNIDIMSMTG
EPVCCLKELTMRRLDPVPVAEIPRELTWTVDWEEGQNVDPVPANAVEVVAIDPLGMQHTV
IKELKQKGFASVQVFERDSSVEEVLRVLRISSSGDSPTSLTPASAAAGEAAKSTSLPHRV
VLFLGTGGANDAIEALDCLLQLSSGLEKAAKEDRQQEFYPIWILTKGSQSHRDKGRVSNP
VHAGLWGFARTARLEISAQTSKEASIGCVDLGPECRVADVVQHLAAIQSQEKYEREILFD
EVEEVEDQKREKGKPPSGSKRLKHFVSRLARSPLNVRGALELHMSDRGSITNLTLRPQSY
AARVTPKGDMVELRVRAVGLNFRDVLNVMNLYPGDPGPPGSDCAGTVVAVGDRVKHLKVG
DSVYGVAPGCLKTYVTTNSQIIRKMPASMSFEEAAALPVVATTVEYVLNDLAKVRAGEKV
LIHAVSGGVGIAAVQFCKRVGAVVYGTCSSEKKREFVESLGVKYVASSRDPEKFTAEMKT
FLGEEGRVDVVLNSLIDKFIPASLALLGKDGRFIELGKRGIWTHEQMRAQRPDVYYEAVA
IDVMISENPRWFGIMLDRVRTLVERKQLLSLPLTVFNMNDPNEGGVAAFRFMQKAQHVGK
VVVAIPSALDFERSTVGPPTTPQKTYVITGGMGGLGLVVAQWLVEEGARHIVLLSRRGEP
SDTVKQSSIWEYLTEKERTCVSVLPLKCDVSVKDDIVSAVKEIEARGFPPIRGIFHAAGV
TADASLANQTREAIEQVYLPKVTGAWNLHEVCESMGLDKNLDMFVMFSSVAALLGNFGQA
NYSAANACLDALAEYRRARGLCAQSIQWGPWIEQGMAADLKALAEKAGLRGISNELGIRV
LVEAVRNSKTVVTFLAQSFIWKRFVQRFDVVPPFFSNIEFETASPGAFRVLYSSMTPDEL
HTYVSNVVLDTARQVLGTSELPALDSPLQELGIDSLGAVELRNSLSQRLGVKLSATTLFD
YPTIRAIIDYIVNQVSGEASAAKATSGALVSAGLAAGRNSPIAVVGYSCRLPQGSETPDK
LWEMLRRAQDCVVEVPLTRFDVDMFYDSDIDAKGKMYVRKACFMDDADMFDNSFFNISAA
EVTYMDPQQRVMLEVAYDAFYSAAYSREHLIGKNYGVWIGCCNSDWHFLEQQSNPDKSSS
YSGPGGSGCLVSNRLSYVFGLKGPSMTIDTACSSSLVAADCGAQAMRFGYCDGALIGGVN
LMLSPQLFLAFCKARMLSPDCRCATFDEKANGYVRGEGAGAIMLRHLADAQREGKRILGI
VRGTAVNHDGRSASLTAPNGPAQQDVIRSALQIGGVDPLDVALVESHGTGTALGDPIEMG
AIKAVYGAGRSADSPLVVGALKSYIGHLEGSSGIAGILKVLLCLRHHEVPPNLHFDTPNP
HMDLSDFHVVLPKKQMKLQPAQKSSTILGSVSSFGFGGANAHVVFEEYPEPTMATDVGGE
RRSTEAAESAGKKRLAFLFTGQGSQYPNMCKQLYEEEPVFRSHMDACFTVLEGKLDVKLR
DVIYPTAENDVEMLNLLNQTGYSQPAIFCVEYALAQLMISKGFSPSVVMGHSLGEYAAAA
IAGVMDWKDALLLVHERASIMQHIDPNDGVMYACRASEQDAQAAVEKALGEKAVAVTVSA
INGPRSIVLAGTQPDVLAVLKAMDMQSRAKQLTVSHAFHCPLVGEAAALLLPKVESVKLS
NPNEGITFISTVTGKAVGAGELTKPEYWATHITKPVQFLQGMRAAVTSGEAGIFIEIGPR
PTLVNMGQQCVPRNDYTWVAPVDPKDSNRNSFPQALEKITSNMVCTYTWKRHAFPWTVVV
HPFVDKFVPDQDETKATSQKLLTPAVGELLHDHVVNGTAMMPGVGFLEAMAAGGFMMVDG
KLPSTVVALRDCEFERPMLIPKIDPSTGEFTQAAKLMITVNNKDITLKSIMDGEEEEIFH
SRCTFSLCPATSLPTEPADLLTSLQGRITTPVPITTLYETLQSVGLQYGARFQSIRECYA
AASDEVLAKLRPKLPLHSFERNFRIHPVLLDGALQTAAVLFAEMGHKRPLVPVGVKRALL
ARVPAGSEVWSHVVVKSKDLRSATMDVTLFSTKGTILGQLVDVAVRAFDAVAGAQIPKGL
LWEVSWVPKAKAPVEDGVDTVENEASETITPTAKLAVKPTGKVEGLARQPAVNGQPKWLL
LKTPSSMLEGLQKALQGTPSAFVKELDEKHPNNAISSKIHNSEWDAIIYLGALSAAASST
TCVADALLLANTLGNTAAEKPLPNVLFVTQGQHFIRECGDVPTTAVPTQTGLYGFCRSAQ
LELENIIGRPVYLGTLDFAAKDPTLDDPAAFVSALQRVLAEADPTGAAGTCEPHTVIRGG
KEMVPRLVKSSIECRGAVELHMSDRGALSMLKLRPMPKSARVPPPRDCVEIRVRAVGLNF
RDVLNVMGLYPGDPGPPGADCAGTVVAVGEGVEHLRVGDAVFGIAQGALKTFVTTSAHLV
RPLPGRLTFEQAAALPVVASTVEYALHDVAKVKKGDKVLIHAVTGGVGLAAVQFCKRVGA
EIYGTCSGGKKEEFARSVGVKYITSSRDPKKFAEDMCEFLGNGKHKIDVVLNCLIENYIP
ETLKFLAPNGRFVELGKRGIWTREQMGTVRPDVLYETVAIDTMMEEDPVWFGGMLDRIRN
LVDGSMLQPLPLHTFEMTDSSEGGVAAFRFLQRAQHIGKVVIRLSSALEVKNFTTNSRQE
TENEDSGERHTLSPATAVGKPLSQSVADQMHKTYIITGGTGGLGLVVAQWLIEEGAHNIV
LLSRRGEPPSSVKAGDPVWKYLCGEEQPNCISVATLKCDVSQKDDLLRVFKEIESRGLPP
VAGIFHAAGVTADAALASQTADSVDQVYLPKAIGAWNLHDACEALGLNKSLEVFMMFSSV
AALLGNFGQANYSAANACLDALAMYRQSLGLCGQSIQWGPWIEQGMAAQLTQHLEKVGMR
GITNELGLRVLGDVMMHPTVAVVGAQSLQWRKFLRRYAFEMPSFFSLVPMAGAGSSEASV
NLATITKEDLCELISSLAQAVSGAAEKPAVDTPLMDLGLDSLGAVEFRNSVADKVGVKLP
QNLMFENPSISSISDYILDKAAGKHGESGVTGANGGSGEGSDIPALDTPLDQWLMSVLEP
AERFALYIDSFASEYGTLQKMAAEEDIITALEDLGVEDGGDFERLHVAWDDLCNQINTAK
RMAAKDIRPSSTAVSVSDHPKPRMPHPMEDVDTLLASLDFDVSTLRPATAPDKVKNVLLT
GVTGFVGRVQLASLMQLKQRPDLRVYCLVRARNADHALSRIREATKEAKCWQETFVSRIV
PVTGDFTQPLLGLSSEEFQELARKIDIVYHTGGDVNLLSNYGRLRATNVLSVKAIIDLCT
TYKVKPLHFASTLGQFPAFFAMFTGHFSGESIREDSTPDVSQMENFYPPSRQGYPWSKWA
AERVLEGARKRGLPVAIYRLPNTYVAYKTGYTNKTDYATALMIASIQEGVFPIGAATAPL
TPVDTICDMLVEASFLEKPKHWVYHLFDPRLVTRADLEQWSQELGISYVGVKVDEFLEAI
KKRGPESPVFKFVPLMQHWRRFWFDPEERTESFPISNEHIFEDLPHMRWPSLREVFKNSL
LYSVRMGFFPKNSKSIILDPQVALNEARRICGLQLMGREGEDFFLHPWRVLQESARRECD
LLFGGQLAVYRTVRHYFMNVMYLADAQAKCPEIEKQEIQAPLIIVGLNRTGTTFLQNLMS
TDPSNRSLRYCEMIAPYGPDGNYRPKGLPNTEESWKKDPRIPFAQEILDSQLGLSEEWMA
IHTQRAELPEEDFVIFEHCGRCYSICTEFSVPSYREWLASDNYKETRKAYSFHKRFLQHL
QWQRPAKRWLLKMPFHLFTLEALFETYPDAKIIFMHRDPKETMGSWASLVKHAQQSLMDN
VDPSALGREELRAMSTMINRALAFRRSHPELGPRFLDVQYQDLVNNPIGVVKSIYKHFGI
PLTLAAQTGIASFCNENRKHRDKLTKHMYSLKDVDLTDGMVQEAFKEYYDSGLCKYLSSA
R
>Q0S9C4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Rhodococcus jostii (strain RHA1)|TrEMBL
MAEKDDDQVGASEATGNVTGSTGDMTVAQLREWLRNWIADATGQPVGQITDDRPMEEFGL
SSRDAVALSGEIEELVGVTLTATVAYQHPTIASLATRIIEGEPEQLDDSADAAYYASAPT
SDAHDIAIVGLASRFPGAGKTPAEMWQMLAEGRDGISDLPEGRWEEFTSDPQIKAAVEKA
NTQGGYLDDVKTFDAEFFAMSPLEVANVDPQQRLAMELTWEALEHARIPASDLKGEQVGV
FIGSSANDYQLLAVSDPVHAHPYALTGTSTSIVANRVSYFYDFRGPSIALDTACSSSLVA
VHQAVRSLRSGESDLALAGGVNMLVAPPATLGFDQLGVMAPDGRIKAFSSDADGMIRAEG
GGLVVLKRLEDAERDGDEILAVIAGSAVNQDGRSNGLAAPNPDAQADVLRHAYRDAGINP
AGVDYIEAHGTGTILGDPIEADALGRVVGRGRADDKPALLGSAKTNFGHLEAAAGAAGLI
KVVLSMQEDTLPPTLNFAGPNPYIAFDKAHLQVIPEGAAWPRYTGTAVAGVSGFGFGGTN
AHVVVREYTGPAADDAAEITEPAVPAEESVAEAVEPTVVLAVSGALPSRRRRAAADLADW
LETEEGSTTPLADVARSLARRNHGRSRAVVLAKTRSEAVTGLRAIAAGKPGQGVFSADSP
SSKGAVWVLSGFGSQHRKMAKQLYLENPVFAAAIDEVDALIEDEAGYSMKEKFLDDAIDY
DVETSQVGIFTIQIGLAALLRHHGAQPEAVVGHSMGEAAAAYISGGLPLEDAVRVICARS
RLMGEAEATLEGDDIRLMALVEYSASEIETVLTDFPHLEVCVYAAPTHTVIGGPEPEVNA
IVARAEGEEKMARVLKTKGASHTSQVDPLLGELAAELAGIEPTKLKLGVYSSVDQDTYYR
AGHEPIHREEYWTKGLRHSVYFTNAVRLAVGSGHTTFVELAPNPVALMSVAATAFDAGLH
DMQLIQTLKRKEDEPLGVLAALAQLYVHGHAVDLSSLLPEGDFASVPRTAWIRKPYWVET
RIDSSGNTRVPGAHVSLPDGRHVWEVQAGAVTDLPALVTAAASQVLSDVTLAASVLHAHT
PAEGTLTTTLNPHPGGASLQVHAKSGPSFTLLFDAAVTSGAALPEPVVAPPVQSTSPVEE
LPEVVEDIGEKWDPNGSQTLEDRLALIVAESMGYAPEDLPAEIPLIELGLDSLMAVRIKN
RVEYEFDIPQLQLQAVRDANLMEVGKYLRYAVENREEVQALADKQKAEKEAEEAAEADRD
AEADRDAEAARDSEFDASPLDAEDTSVEAEAEAILAATPVPETAAAPEAAAVDSKEAFAD
ATGSDVPPRDAAERLTFATWAVVTGESAKGIFNTLPILNDETAEKLAVRLSERANGEITF
DDVLDSTTIEELANVVRGFLEDSGKIDGLVRALRPRPEGSDAVPVFVFHPAGGSTVAYEP
LLKRLPEGTPMYGFERTEGPIEVRAAEYLPLIREIQGDGPYVLYGWSLGGVLAYAVAKLL
RESGADVRIVGLIDTVMAGEKVEDTPDEIRKRWQRYAAFAKKTYNVDYPLPYDKLAAAES
DEEQIKILTELLKLSGTKIPGGIIEHQRTSWLDNRAIQTAELAQYDGDVVLYMADRYHDD
VMNLEPAFKTRKPDGGWGDAVKNLEIIHVGGDHIQIVDEPYIAKVGADLTKKLAAIQAAG
TGAHQ
>A0A1B9VN15|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Thalassospira sp. KO164|TrEMBL
MRTNTFAPGTERQGKPLTTPQSSIWLDWAEGDDCANYNICSVIRFEGDLDIAALYKAIVQ
TDQENDALRLRFASEGGKPFQTFADDCRETDFSVIDLSFTDDPVLIANNEVEEIRRRPLD
PENGYHCRHRLLQLGTGRYWWVRVYHHLVCDGYAGHLMAQRAAEIYSALKTGTAVPESTF
GSYGDFIAADATYPETPAYQRDLAYWQERLQNDHAITRFSSDKPSGKLVQARLEQTLDGH
DLAKLIHTAKACGTSPTAIVMAAYFILLGQVTHIKQPTVTMPLLNRMGRTERQTPGAFSY
IVPFDADLSKHTRFSELARDIFARARRDVRHMRLGAPRMRAARLGARGLSGNGAFFNSLD
GAEPLSFAGLDTRRVNIYNGPVTDLGLIYMMQAISPDRQEAEIIWQYDTACHDVKSVTRI
AERFRYFLSRALDDPEQDIAAIAAPPMNELAIIRTLETGPTFTRPAPVRLIPERIDHAIA
SRPGDVALITEDDHEVTFATLGHMANAVAHHLKQCGIAPGDFVGMNISPSAQQTAAVIGI
LKCGATCVQLDPLQPIARNASMTRHLDCRLVLSDNTDTWHKIGDTSITVNDINAVTGIDG
SITFENIHADICGDDIAFVFHTSGSTGQPKPVPVHHQSLADKIDVAIAQFGIGSHENGNP
EIMGLFPSLGFDPWMLQFCVGLIRGHRMWLMTHAILSDGHKFWNGVARHHVTHIMSVPSF
YESVIDAVPADGAFKLRRLITGGEIMQPTLVRRLYSAFETVDIWNCYGPTEATIHAAVYL
IPRAPQTKSIPLGRIDKGGFVRILDEDGKRVPLGVPGEIYLGGAGLNRGYINMPDVTEEK
FVTDPTGETDETFYRTGDLVSWGEDGLLYFHGRTDEQVKIRGQRIEIGEIEYQLSRLSGV
GRAAVLHVKTKHGGELIGYLLSNASPSKRPDAATVRAELARHLSDAAVPTRIEWVETLPL
LPSGKIDRKALAEFARNPDGKQPVASKASPPASRKPDQARIHQLAGKIARIWMELIETDE
IEFDTNLFEAGAHSLLVPRAQFALSKLAGRNIASVEIFQHPTINSFARHLCAGDQHAPET
AQAEPVKPQRNVSENHDIAIIGMAMRLPGANDRDAFWSMLENGIDQIKDVDISRLRAMGG
DPSALEDADFIARHGILDDLDMFDPAPFAMTAGETIETDPQQRLLLEVALSALEDGSCDP
ARDGPVGAYVGVGFPTYLVDSLRDRLRDRPDAIRYGMTLGNDKDFAATRLAYKLNLTGPA
IASSTACSTGLVNLALAVNALRSGQCRVALAGGAALGLSPAGGYYFTQGGIGSRSGVCRP
FDSKADGVVGGSGAAIILLKRLDDAIADRDTIHAVIKGVGINNDGSAKAAFTAPSVDGQA
KAIQTALDDAQIDPSTIRFVEGHGTATALGDPIEIAALNKVYAKADTTPTHPKWLGSVKG
NIGHLDSAAGMAGLIKAVLAIRHRVFPPTCHFNQPNENLGLDQGPFQINNTAQPLSNNDD
EPLRAGISSFGVGGTNAHVIIEEAPRFDEPASRQTQNDIPRILPFSAASEPALQKLLENT
ASWLDRNGSDIAISDVANSLSRRHAYRFRAAIVATNIKAAVSALTHPKSTARHQAVAQRN
IPPIAFLFPGQGSQRPGMAKGLYEVDQTSAKMIRDACKHVAQTGGPDDLFELLTVPDESP
ATSSRMARTEIAQPALFIYEYALANWLIENGILPAALAGHSIGEYVAACIGGVMSFEDAL
RLVVMRGRLMGQTEPGSMFALSMTEAEVGDLLSAFGPDLSMAAINGPRQCVVAGSTECID
ALEEYIKSQGKSGRRLVVSHAFHSRMMEPVLNEFRHVVAKIRLNAPTLPIQSNLTGNWLT
PEDATNPDYWVQHLRNAVRFADNIKGLLAEMPETIMVECGFGNTASRLAIVNGTATGNSI
ALQPAPGPDAARKTDAAITGSNALAVAISRLWVMGTSPDWDRVNQTRDAHRIPLPTYAFD
RRRFWPEKATTVNADPKSIAVAAAPVEATLPPARNPAQNTSDAQTETHTQSAILAVWRDM
FGDPAIGPDDDFFELGGDSLFAVRIATRLSEVLTAEIPTAVMFEGRTVSGVANLLASFET
NSPPTNARSAPTATATAKPATTAPRPSREQGVL
>A0A447G915|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium basiliense|TrEMBL
MLRERASLRPTETAFTYIEYEQDWAGVAESLTWSQLHRRTQNVARELKACGSTGDRAVIL
APQGLDYIVGFLGALEAGQIAVPLSVPLGGASDERATAVLRDASPSAVLTTRSVAGGVAE
CIESTSGERAPSLIEIDLLDLDSEQGPAADMGQLPDVAYLQYTSGSTRTPAGVVISHKNM
VTNVEQGMCAYFEDQGRSAPPDTTVVSWLPFFHDLGLVFGIIMPILQGFHGVLTSPVSFL
QRPARWMQLLATNSQAFTAGPNIAFELAARKTSDDDLAGLDLGGVRHILSGAERVQPATL
QRFTERFARFNLDPKALRPSYGLAEATVFVATLELGQPPRTVFFESDKLVDGQAIRCATG
DGTPLISYGAPQSPLVRIVDPETSTECPAGTVGEIWVHGDNVAAGYWQKPQETERTFGAT
LIGPSAGAPEAPWLRTGDLGVLSEGELFIIGRIKDLLIIYGRNHSPDDLEATIQEITRGR
CVAIAVPDEGGVEKLVVIVEFRTREKSEEAAAHRMGAVRREVIAAISKSHGLNVADLVLV
PGGSIPLTTSGKVRRRECLQRYLHDEFTRVDGMVPEPEPRKIDDAGAGGADSGVVQRLRS
LRQQQHDLLVGMVCAQAAAVLDYPSPNDIDPECAFQDLGFDSVKATELLDRLNTATELAL
PPTLAFDYPTPAELATHLGELLGGGVAAAQPVGSRVGTDDPVAVVGMACRFPGGVDSAAA
LWDLVANGTDAVGEFPADRGWNLAELFDLDPDAAGKTYTRTGGFLAEAAQFDAEFFGISA
REAQTMDPQQRMLLEVCWEALETAQIDPAGLVRSETGVFVGAWSQQYGAGGSDGVEGYGL
TGLSTSVASGRVAYALGLQGPAITVDTACSSSLVATHLACQSLRNGESVLALAGGVTVMT
TPTMFTEFARQRGLAADGRCKAFSANADGTGWGEGAAVLVLERLSDAHRNNHPVLAVIAG
SAINQDGASNGLTAPNGPAQQRVITQAAANAGIGLDQVDVVEAHGTGTTLGDPIEAGALI
ATYGAARTAAHPLWLGSIKSNIGHTQAAAGVAGMIKMIGALNHDRLPPTLHADLPSPHID
WSAGTVRLLTEPVPWPVTDHPRTAAVSSFGISGTNAHLILQQAPTPLAEPADPRTPTEQT
DRGVEVGLPVGPMWPVSARTPAALCAQADRLHQHLVRHPDLAVTDVAYSLGCTRTHHPYR
AVITAPVAAADPREDLLEALDALRAGRAHPQLTQHHYLAHLRGKTVFVLPGQGGQYPGMG
RELYENHRVFADTVDDCDQALRPFTDWSVRAVLRQDPTAPALDRVDVVQPVLFTMMVSLA
EVLAHHGIVPDAVIGHSQGEIAAAYIAGVLPLPEAAKVVARRSQALSALRGSGAMASVLL
SVNELQPRLHPWGDALSIATMNGPTHTIISGEPAALEEFTAACDRDGIHIRAIAVDYASH
SAQVEPLRERLLSELAELAPAPARIPLYSTVGQALSSGPLDTTTMDADYWYRNLREPVGF
HDRVVELLAGGQRTFVELSPHPVLAPAITDTLAQTAGRTQSAVITTLHRDRPDRDSLATA
LAQLHTHNHSPSWRRLYPDANIVALPNYPFQHRSYWLAPAPAAEVGAAGLGQPDHPLLGA
VIDLADQDQVVLTGRLSTAAQCWLSGHQVNETVLFPATGFIDLVLQAGEYAGCPVIDELV
LHTPLLLHDQAPTDLQISVHPAEDTDRRPFSVHSRTGGEHAQQAWTLHASGVFSTEQRPV
PVVAPGPATDTTDQDSFYQELAEHGYHYDGPFRSLRSIGHDPARPEVVYAEIELPADTDT
TGYGIHPALLDAALHPLAAAFCRTAADDDAAAPRLPFAFTAITLHATAASRLRVQLTATG
PDSFTLHAADPTGAPVITIGTITLRELPAANGQPAAVPGLQDSVFQLSWPPLLDGASPTA
AAGTGWAVCTDQPDRLPAGLRNGPIHHDLATLTPAPELVIWPMPLPDPGEDAHPVDRLHV
LTRRTLAQLQDWLARTDVLGTHLVIVTRHAVSVSAHDDVPDLAHAAVWALIHTAQNEHPH
RITLLDTDATLATEDNLLAIASTRPANEPQLALRNGAARMPRLARSSTLTEPDATDWQLI
TTGKGDINHLTLIPTSPPSTLGPGQIRVQVRAAGLNFHDVVVALGAITDEGLGAEAAGVV
IETGPDVASLSPGDAVMGLFPTNAFAPTACTDERMVVPIPAGWSFTEAASVPIAYLTAYI
ALVGIARLSAEQRVLIHAGAGGLGQAAIQIAHHLGAEVFTTAHPNKHHVLNDLGIDSGHI
ASSRTLDFADTFRDATARQGMDVVLNSLSGDFVDASLQLLPRGGSFIEVGKTDIRAASDI
ADGHPGVDYQTLDLASVSAESLQPAWTALTELFAAGTLKPLPTTSYGLLNAPQAFRDMSQ
GLHTGKIVLIPPPRWDPQGTVLITGGTGMLGAIFAEHLVSRYGIEHLLLLSRGGPAAAGA
AELEERLTRLGAQVTITACDTADAADLAAVFDSIPAQHPLTAVIHAAGVLDDAVLADMTA
EQLDAVLAAKADAAWHLDQLTRDRDLAAFVLFSSAAGTLGSPGQANYAAANAFLDALAQQ
RHRYHRPATSLAWGYWQTPSGMTAHLTSTDQARLTRNSFIPISSEHGLALFDATLPQQLP
ALVVSPFPTRALARLARQNALPPILSALTTSRPRASATSVESLQTRLASQTPEQRRRTLS
ALVTTATANVLAHPDPATLDPDRPFKDLGIDSLTALELRNALNQQTGLTLPATLIFDHPT
PATIAAHLADLFTDTAEPPALATRVSVGRDAPVDNRLADLDQTAFLALRAMHGTLLQATW
IYDRAVNVDGLRRFHRNLGHGLLGRRIERSPVPFARDHWVMSPVSAEIDIATTPRPRSEV
SAWTDKRARLPIDPEWGPGWHLGVLPLEDGGTAVTLVASHAIVDAIAFGQAIAEAAEGRA
HDLGYPQPKARTRRRALREDLRQSIKELPDVAHAVAAVARRARRDRKELNSSIKAAPRPP
RTAGDDRTVEVPAVTAFVDLTEWDGRAKSIGGNSNSLVAGLACRLAVGMGRVLDDGTVTL
RFPVSLRTDGDTRGNALTAVDVNVDPTHAAKNLGDIHVEITQAILSTMENPDDETLAPLP
LAPLTPRWVARKLAAMASGGGTLPITCSNIGDAPPSTNRPDGTDADYVYMRSVEPDITKS
ALEGMGGYVLLASGRFRGKISIRISAYLPGWSNTKDALRELVSRTFAEFDLTAEIDY
>I8TXY0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pelosinus fermentans JBW45|TrEMBL
MGNDGKFSCYIIGDGALLTACGELIIDSGHDIYGVISSNPSIREWAEDKGLTCTDHDSDY
VDFLKQNPFDYLFSIVYLSLIPRKVLALPQRMAINFHDALLPEYAGIHATSWAIMNQEKQ
HGITWHEMVSAVDKGNILKQMIIPVEEGETAHSLNVKCYKAGLESFRDLVEELAGDSYSL
TFQDLSRRTYYGKYQHPPAGGVISWDSSAEEMDAAVRALQFGKYQNQLGIAKLAVNNEYI
IVDQIFVTKNKSDAKPGTIVAIADLNFTVATVNNDIEIRSIRSIHGVQLPISDCIEKYHL
KAGGLLPGFARKTSTRITALHKQISRFEDYWIKKMSKMDAAIWPGAIQSVEGIDSIHNSF
VDFTIAEEFITYAEQDYGNRLASCLAAISTFLSKECKTNNVQFFLGYQELREDFQGVDTL
FAVHVPVELELNDTLTFRDTCDIARAEIQSVKEHKTFLHDLIARTPQLKSNSPVHEKKLL
SFTVEYVKDLTDYSQLACNRYGISLIVPEMGNTWRIAFDEALLATAKAVNGTNRLAACMA
RAAATPDAPISKLTTLTDAEFHKAIYERNHTVAEYPRDKCMHELFKERVKQSPEKIAVLC
RDESLTYMELEEKASRLASFLNRAGVGRGDLVGIFIERSLDMLVGLLGVLKAGGTYVPID
PLYPGERILHMIEDADIKMVLTQNEFKHKLPGSNARIICLDTDWEDICINSGKSSSRKYY
SYSSKTVRPEDSAYVIFTSGSTGKPKGVEVTQRGLTNFLCAMAKCPGFTKEDRVLALTTI
CFDIAGLELYLPLITGGQVEILPTETARDGFALKERIEKEWATVVQATPATWEMLLEAGW
DKRTSIKILCGGEALSRQLAQKLLDRSKEVWNMYGPTETTIWSSVSKINLGEEITIGYPI
GNTQFYIVDEHLNPVPDGVEGELCIGGDGLAKGYLNRPELTSEKFILNPFAADLQLKMYR
TGDCAKYLPDGRVVCLGRMDNQVKLRGFRIELGEIETVLQKQLHVKHAVVVMKADSTGYK
SLTAFMVPDKFQDLIAGSKLREAMREFLPDYMIPASYVYLEMLPLTLNLKVDRKVLSAAP
DFQLIEKYGYKEMNHHIHIPANDSIKTLEWKEEESKAAGHFAEDLTKIIAGVVKISAEEI
HAEIPMGEYGFDSIRFTVLSKRIKDAYNISVTPAQFYTYETVNKLIDYMSKTYQEELDKH
YGKETKGIQDSLSKSKVEAADSAHEAAFDLFSRDLTQLVAGVVKISAEEIHAEIPMGEYG
FDSIRFTVLSKRIKDAYHISVTPAQFYTYTTVKKVIEFLWHAYRDELQKSYGDVSVEVKT
ISGRSELKNKEMNSVVNFNKTNMEFDSDQRKWKKEPVAIIGIGGIFPQAPDLDTFWDHIV
NKRDLITPIPWERWDSNHYYAKIAEEKKIPFAKWGGFLEDVDKFDAAFFNISPREAEQMD
PQQRIFLETVWKAIENAGYKASEFSGTKTGVYVGAVSSDYWDMMLCSGLEADSYTISGNI
NCVIANRVSYLLNLQGASATIDTACSSSLVAIHRAVTAIQHGDCDMAIAGGVNVILNPFM
HTALGINGMLSADGRCKTFDSQANGYVRGEGAGVLILKPLSKAIEDGDNIHAVIKGSSEN
HGGRTNSLTAPNPNAQAGLLISAYSEAEIDPSTVTYIEAHGTGTSLGDPIEINGIKMAFE
ELGKKWGRIGPEKYCGIGSVKSNIGHLEAGAGVAGLLKIVLAMQKGALPGMIHFKEQNPY
INLEGTQFYIAAETQKWQRIRDSAGQTVPRRAGVSSFGFGGSNAHVVLEEYCGTKTNAEI
NNNISNVFLLSAKSEDRLRAYAIDMLAFLEEVAAREEKGEWIGTLFTDIMYTLQMGREAM
NKRLAIVASNIKELTEKLRQYCADEKEITQVYTGAGGLETKNISALLEGSNGKEFLAAII
RQKEYKKLAHLWVGGAAVDWSLLYSHSKPVRISLPTYPFAKERHWLPINKNVLVSKYEVQ
PVRLHPLLHQNTSDFFEQRFSSVFSGNEFFLKDHVVKGQRVLPGVAYLEIAHAAVILASG
INEKQNSIKIKNVTWIRPMIMGDKELQAQIRLLPEENGDINYEIYSQSALDGTAATVHSQ
GRAVLSPITEPPPLDLQALQRQCSHGTISFGQCYEAYRTMGIDYGPGHQGIREIYVGEYQ
VLAKISMPSCVRDMQEEFIMHPSIMDSALQASIGLIMSYSEIEPSKPIVPFALQEIEVFQ
KCTSAMWAHVCYSNGSKPGDKIQKLDIDICDELGGIYVRLKGFSARVMEKDNIQKESAAV
LETLMFHSSWIVKDANAEAAFPDDTQQIVIFCEPDEMVKEKIKEKMNSNRYLILQSNQEQ
LEERFQSYVFQVFDEIQNVLRSKPRHNVLIQIVVSIQEEQQLFSALFALIKTAELENPKV
WGQLIEVELGESWERFSEKLAENSRCPMDRRIQYLNGKRRVAVWREIERSHEVLTTPWKE
QGIYLITGGAGGLGLIFAQEIAQQVKNPVIILTGRSALNEEKRKKLKRLVELGAKIEYRQ
ADITDKKAVIRLIQTIQEQFGDLHGIIHAAGVIRDNFIIKKTKEEMQEVLAPKVSGLVYL
DHATRNMKLDFFILFSSISGSLGNVGQADYAVANDFMNAYARYRNALAAAKQRQGQTLAI
NWPLWQAGGMNVNEAIEKMMRNMGMGAMPTASGLRLFYLGMNTDKDQVLVMTGEPERIQE
KLLLTAYFSQPDKITAASTFTEAAYASNLLDRIQSLLIQMTSKLLKVRMEEIDSNTELNE
YGFDSITFTEFANQLNQEYKLELTPVIFFEYPTLNRFAEYLLESYLAEFSSQLAVQKDTD
LNGFKEPEFMASSPKVIDNGSLLENIQMILIQVVSRLLKVRANDIDRNTELNEYGFDSIM
YTEFANLLNQEYKFELTPAIFFEYSTIQSFAEYLTKEYRTLLVSQFAAAVNVEQTAIYVP
AEGLHTKSYSRFIKTMPLTLSKVDEKDQEAIAIIGVSGIFPMAKDMNELWKNLLEDKDCI
TEIPKSRWDWREYYGDPGKDINKTNIKWGGFIDGIEEFDPLFFGISPREAELMDPQQRLL
MTYAWKAIEDAGYSAQSLSGTQTGIFVGTANCSGYSGLVSLSNTVIEGYSATGTLPSVGP
NRMSYFLNIHGPSEPIETACSSSLIAIHRAVAAIENGACEMAIVGGINTMVTPENHISFN
KAGMLSEDGRCKTFSDQANGYVRGEGVGMLFLKKLKDAETDGDHIYGIVKGTAENHGGHA
NSLTAPNPKAQAKLLETAYTKAGIDPRTVTYIEAHGTGTELGDPIEINGLKAAFKELYQA
TGDDAVTSRHCGLGSVKTNIGHLELAAGVAGVIKVLLQLKHKTLVKSLHCDTINPYIQLA
GSPFYIVQEQTEWKALQDAAGKEIPRRGGVSSFGFGGVNAHVVIEEYIPRKQEPITISDQ
NPALIVLSAKNEERLKEQVQQLLNAIEGQRFFDSHLADMAYTLQVGREAMEERLAIIVGS
IKELEERLKCFIEGQQNIRDLYIGEVKRNKETVAIFTADEDLERIIDVWVAKRKYKKLLN
LWVKGLSFDWNKLYDNAKPQRISLPTYPFAKERYWIPSSESKDVSKSVAPMTVIHPLLHQ
NISDFSEQRFSSTFTGQEFFLTDHVVKGQRVLPGVAYLEMARVAVAQAAGVLNEDERKIR
LKNVVWTQPITVKERPVRVNIGLFPEDDGEIAYEIYSHSETGSAELVVHSQGIALLSVIE
GVETLDIRNLQAECSQRILSSNQCYEAFRERGLDYGPGYQGIERVYVGYDQVLVKIFLPS
SVSSTQDQFFLHPSLLDSALQASIGFVLDNDDFKLALPFALQEVDILGECKSNMWALIRY
SEGSKAGDKVQKLDIDLCDETGLICLRMKGFSARILEGKIEKIRQKLIPIATSETISDST
NIYLPNKMKVALMQIVSKVLRVKIENIDANTELEEYGFDQIMLGEFANNINQEYKLELTN
TIFLEYPTIHSLAEYLVVKHQELFAEYFQIQISNEPSKIKEKSLVIKIGEDLLREKATIY
FKQLLSSVIKLPAQRIEADAPMERYGINSIMVMQLTNQLEKKFGSLSKTLFFEYQNIQEL
TGYFLESYRSKLIELLGIEEKATATTEMSNDNIDMTVSIKSNIDTHRRPRFAALRTECKE
EKKSEGLDVAIIGVSGRYPGARTIQEFWRNLREGKDCITEIPLDRWDHSLYYDEDKNKPG
KTYSKWGGFLDGVDQFDPLFFNITPREAELMDPQERLFLQCVFETIEDAGYTREVLRHYK
GFGLEGNIGVYVGVMYEEYQLYGVQETIQGRPIALAGNPSSIANRVSYFCNFHGPSMAID
TMCSSSLTAIHLACQSLERGGCELAIAGGVNVSIHPNKYLMLGQGRFVSSKGRCESFGEG
GDGYVPGEGVGAVLLKPLASAIEDGDHIYGVIKGTAINHGGKTNGYTVPNLNAQSGVIGQ
AFKESGINPRTISYVEAHGTGTSLGDPIEVAGLNKAFQQFTDDKQFCAIGSAKSNIGHCE
SAAGIAGVTKILLQLRYHQLVPSLHSKVLNPSIDFSNTPFIVQQELAEWKRPFVNGHEYP
RRAGISSFGAGGSNAHILIEEYILKDEKQILITINNQKPAIIVLSARTSEQLKEQVQRLL
VAIQEEKLSDLNLADMAYTLQVGREAMKERLAVVVESITELEEKLKGFIEGQDDDIEGLC
RGQVKRNKKTLDVFAADEDMTKTIEAWIEKGKFTKVLDLWVKGLIFDWNKLYSNSKPRRI
SLPTYPFAKERYWIPGIENQIKSNSLFVQNKNQFSDVFYDKLMDEIISDGISVDVAIQKM
KNTSQIK
>A0A0C5PUC2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pelosinus fermentans JBW45|TrEMBL
MRRKEILTAFKKGELTAIEVKEKLYKLKKQPFQNPLSEGQKGLWMLQKVLPEMSSYNIPL
CFRVFEKVNIDKFKKACHFVLEEHPILTSVIEEDSDGVPYQTIESSRPLTFQQEDISNLK
CSEILSYLREKAKEPFCLENGSLMRVHLLFRSEAEYIVLITIHHIVFDGASSVLLMTTLL
NAYQELAKDRNPIPNSSLASYYDFIEWEHKMLISKEGEEHRSYWRQQLSGNLPILEIPAD
RPRFSSRSDIGETYTNLLTPELSKKIKSFAQSQHLNSSIVFLGIFKLLLHRYTGQEDIIV
GMPTMGRIQEGFDSLIGYFVNMIPMRSQVEGTKSFSKFIRELQVTVVDGLDHAYPFPSLV
RDLNIPRTSLNAPIFQVAFLYQNFLHPTGLKEWQSKLPIEFVEGIHQEGEYEFGLEVYEQ
EERFVLTIKYNSDLFDLSTITRMMGHYAKLTEEIIDDPSVALEEYSLLSKEEEITLTDWN
ETHADYPSDKCFHELFEKQAQKTPNTIAVVYEEGCLTYKELDERSSQMAIYLQKLGVFPD
CLVGICVERSLEMIVGLLAILKAGGAYVPLDPHYPKERLEYMLQDSKASFLLTQSKLLGK
ISPLIEGNIKTIVLDKDRHEIEQEVKVEDTLKREVQSNHLAYVIYTSGSTGKPKGVMIPH
RALTNFLISMGDRPGIHSQDRLLAVTTYCFDIAGLEFYLPLINGAQCYICSSEKAKDVEK
LKREIQRNKPTIMQATPVTWTMLFHAGWKNEERVKILCGGEALPERLKQYFIDTNSDAWN
MFGPTETTIWSTVQHIKKEESITIGKPIANTKIYILDNNGKSTPIGIPGELCIAGDGLAR
GYLNKPVLTAEKFIPNPFNLVTQLYKTGDLARWLADGNIEFLGRNDQQVKIRGFRIELGE
IESQLKNHPEIQESVVIVNEQEGIKQLIAYYVRTNPGRDKASLSLPKLREYLKSNLPDYM
IPVLFVEVDSIPLTPNGKIDRKDLMNRKIVLTGTKKTFSPPSEIEEKILEIWKAVLHNDN
INIEDGFFEVGGDSLLAVAVAERIKKKLKCDFNVTTLFEYTNIKSISKYIAENKDTIAVS
YDRENRNSGNDNLDNSEIGHNKKNRKSSYPEYYQDSLAIIGISCHFPGAKDHFEFWHNLR
EGKESVKFFSQGELRNLNIPEEIIQDPNYIPVQSTIEGKDLFDPAFFNISPKDAAAMDPQ
FRLLLLHSWKAIEDAGYIPRKIPETSVFMTASSSIYQALLLNSKSEENNILMNSDEYVSW
ILAQGGTIPTMISYKLGLKGPSFFVQSNCSSSLVALYSAYQSLRSDEAKYALVGGANIFP
SSNLGYVYQPGLNFSSDGHIKAFDASADGMLSGEGAAVIVLKKAVDAIEDGDHIYALLRG
IGLNNDGSDKVGFYAPSIKGQAEVIRKVLNSTQINPDSISYMEAHGTGTKLGDPIEHTAL
SDIYKQYTTKKQFCGIGSVKTNIGHLDAAAGLAGCIKVALSLYHNEIPPTINFKKPNPNI
DFTDSPFYVVNKIKKLEKNSSPYRAALSSFGIGGTNTHAIFEQYTSVEKPEYLNRQLYND
NIFYMLPISAKNNDRLKDYAQNLLSFLKEPRNHNDDKFVEAAAYHDINLADLAYTFQVGR
EEMENRLIFVFNNKNELIQKLEEFIDGRENIDGCFRGEVKQAKDSIQLFKKDDEFEELIH
KWITKGKVRKIAELWSKGLCIDWELLYLDAKPHRISVTTYPFAKERFWISKIKAESISGI
SANTPAMMGCLHPLLHQNTSNLSEQRFSSTFTGQELFWANHVVKGQRVLPEVAYLEMVRA
AVEQATKNLEEVKTGIRLKNVIWDRPIVLGDKPVQLHIGLFPEDKGEIAYEIYSQSEESS
GEIVVYNQGSAALFSSTKDAETLDVKALQVKCKQNVLSSTQCYEAYRKMGISYGAEYQGI
EKIYVGLGQVLAKLKLPSSVAATQDQFVLHPSLVDSAVQASLGLMMSSDNLNFVRPLTLK
EIEILGNCTFTMWALLRFSDGSKAVNKTPKFDIDLCDDQGKICVRVKEMELHENTEKVIT
ASLEPRPQNVMTPKIQEDFEMMTFEEILQEEALSKRAPVQIKTIVCFLSNLRNQQAIVEA
IRTLEQQTNVLFISQGTTYQKHSQEAYTISRSDKKTYEQAFQSIREEYGEVDAVLYLWPL
EDSIYIQDYSVIVYMLQSIAAVKLKAKQVLLGAQFENGLERCYLDSWIGFERSLRLVLPN
TQVAVMYQESGGQKQESFIKDWMKKIWSELQTKKLQSVCYQKGKRHVYQIKATTLQMGNC
LLQTGGTYLITGGCGGLGFLFAKHFAKTKPVNLILTGRSPMDEKKQNKIKEIEELGSQVL
YLQADTCNVSNMKAVLIQAKEKFGKIDGVLHAAGLADSQSIFEKDMEDFKKIVEPKIKGT
LVLDEVLQTEALHFICYFSSSSAILGDFGSCDYAIGNRFQTAYAFYRNVEQRQGKTLVIN
WPLWRDGGMGVGEEENSKMYLKSSSQRYLEAEEGVLLFDQLLAQTNTQHLILVGNRSKVY
RFLELTQDQSSMPPTISLTSSGKGRRMEMKGLSFEQCLEWDLKEHISQLLKISRDKLDRE
DNLADFGFDSISLAQFANLLTNHYGIEITPALFFGHSTIEKLIQYFFAGYQETMQLFYQE
STVLPEAAQEVLAVTLTSRRQEFKKIRIAMENTPQSMQEPIAIIGMSGRFPQASTIDEMW
KILADGKDVIQDFPADRFSGKGKSPYQYGAIPGVSEFDPLFFEISPREAESMDPRQRLLL
QESWKALEDAGYGSSQIQKSKIGMFVGVEEGDYRLLLKEKSSITSNHNAVLSARLAYFLN
LSGPNMAINTACSSGLVAVHQACQSIRQQECDTALAAGVNLLLTPQMFQGMSEAGMLSED
GKCFAFDKRANGMVPAEAVAVVVLKRLSQAKADKDPIYAVIKGSGINYDGKTNGITAPSG
ASQTKLLKSVYDQYQINPEDLEYIVTHGTGTKLGDPIEVNALYDAFKDYTKKQGYCALTS
TKTNFGHALAASGLVSLISLVQAFRHETIPASLHFQKENEYIQWSGSPFYVNKESKAWPE
KEEKRRMGGVSAFGMSGTNVHMVLESYPENRMEMKKTSPCYLLAFSAKTQESLQEKCKEM
IVCLEKEKAKSLGEISFTLLEGRQHFAHRCAVVVQDKEDGIYVLQQMGSKEKLPNLFKGI
VARDFTGQKAIEEYGQELLAQSFSQADTNRYKEILHALADLYCQGYDLAWRQLYGEEKPN
RLHLPGYPFAKESYWVPEVESSLNNRTKLESVTVIHPLLHQNTSDFSEQRFSSSFTGEEF
FLKDHIVKGQRILPGVAHLEMAWAAAQQTAGALMEEKTGMRLKDIIWAQPIVVGEEAAQV
HIGLFPKENGEISYEIYSQMKDNVKEAVIHNQGSIALVNYMEERKVLDLKALQAECSQGI
LSAAQCYKRLKAAGMEYDTRYQGIESVYLGVDQVLTKLVIPSSILDTQEQFNLHPCLLDS
AMQVIGLQMTVEHCRPAAIIALEELAIIGQCISAPWVRICRDRKSERFDMDFCDDQGTVY
MQMKGLEIQVYTEEMNMIPSEKNSQYPKIHNSQYPVAQGRRAEMKGFTLEQCIDWDLKEQ
VSQLLKIPRDKLDREENLAEFGFDSISLSEFAGIITNHYSIEFTPALFFGYSTLKNLTQY
FLTEYQDVMQLHYREAVMEEGRQVVQAVPAVTLISKRQTSIQSRFITKPASQEIQEQEPI
AIIGMSGRFPEARTIDEMWQILAAGKDVIQDFPADRFSGKGKSPYQYGAIPGVSEFDPLF
FEISPREAESMDPRQRLLLQESWKALEDAGYGSSQIQKSKIGMFVGVEEGDYRLLLKEKS
SITSNHNAVLSARLAYFLNLSGPNMAINTACSSGLVAVHQACQSIRQQECDTALAAGVNL
LLTPQMFQGMSEAGMLSEDGKCFAFDKRANGMVPAEAVAVVVLKRLSQAKADKDPIYAVI
KGSGINYDGKTNGITAPSGASQTKLLKSVYDQYQINPEDLEYIVTHGTGTKLGDPIEVNA
LYDAFKDYTKKQGYCALTSTKTNFGHALAASGLVSLISLVQAFRHETIPASLHFQKENEY
IQWSGSPFYVNKESKAWPEKEEKRRMGGVSAFGMSGTNVHMVLESYPENRMEMKKTSPCY
LLAFSAKTQESLQEKCKEMIVCLEKEKAKSLGEISFTLLEGRQHFAHRCAVVVQDKEDGI
YVLQQMGSKEKLPNLFKGIVARDFTGQKAIEEYGQELLAQSFSQADTNRYKEILHALADL
YCQGYDLAWRQLYGEEKPNRLHLPGYPFAKESYWVPEVESSLNNRTKLESVTVIHPLLHQ
NTSDFSEQRFSSSFTGEEFFLKDHIVKGQRILPGVAYLEMARAAVQQAAGRSGKENIGIQ
IKNVVWSRPIGVGEEAVQVHIGLFPEENGEIAYEIYSHLDESLEEAVVHSQGNILLRPAC
EVKSLPIEQIRKQCSREILSSSQCYEQLRTMGLEYGPGHQGIETLYIGDNQVLAKLLLPA
FLLDTQDSFILHPSMMDSALQASMGLMIGSGSLKPALPFALQELEVMAACTPSMWAVVRY
SPGSKGEDKVQKLDIALCNEEGTLCVRMKGFSARILEGEIDSGANIDMLLYQHGWKEKCI
DQTATVSHIDQHMVILCEPDQGIQDSTAMNMNGVRCIALQRKGGNIAVRFQGYAYEILEE
IRAILKEKTNSKALIQIVIFSNEQMPFFGFSGLLKTAHLENARLIGQIIEVEPEDSAQSI
REKLIENSHQLFDSHIRYQDGKRWVTEWKEIEDTQDTVKIPWKDQGVYLITGGSGGLGLI
FAQDIARQAKSATIILTGRSAFTQEMQTKWQGIVTLGARVEYRQADVTDQQVVSRLVEKI
QEEFGGLHGILHCAGVIRDNFILKKTQEEMREVLSPKVLGLVNLDQATKDMKLDFFILFS
SIAGSLGNAGQADYAAANAFMDAYAEYRNDLAARQQRQGKTLSMNWPLWQEGGMGVDEIT
EKIMMQNMGMIALQTANGIQALYQSIGAGENQVMVMVGKADQFRMALEQNHPDERGEHSS
VYAAAGDKIINQDLYQKLFDEIAAGVLSEEEFSTLMKV
>A0A0C5Q0M9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pelosinus fermentans JBW45|TrEMBL
MSMFGELGSVAASSSLEQKVDIGLLREKTLYQLKVLLAEFTKLSISKIVSDEPLESYGID
SIMITQLNEKFASIFGEVSKTLLYEYQTLGVLVEYFISDYPQECMKWTGLIEPVPSTPEK
KPDVVPFHSEFPVLPSFKERKHLVRSLTAVASSSDGSRDSIAIIGMSGCYPQAKKLKEYW
GNLQSGVDCIIEIPKERWSLEEFYYSDQQEAIARGKSYSKWGGFVEGFADFDPLFFNISP
RETLNMDPQERLFIESCWEVFEDAGYTKDELKVKYNGRIGVFAGITKTGFDLYGPDLWKQ
GKKDFPHTSFSSVANRVSYLLNLQGPSMAVDTMCSSSLTAIHEACEYLHRKECEMAIAGG
VNLYVHPSSYNGLCAQQMLSADGQCKSFGQGGNGFVPGEGVGTILLKRLSQAIIDEDHIY
AVIRGTSINHDGKTNGYTVPNPTAQGDVIRKAMDKAGVNARTISYIEAHGTGTELGDPIE
ITGLTQAFRKDTQDTGYCAIGSVKANIGHLEAAAGIAGVTKIVLQMQHQKLVPSLHTKKL
NPNINFKNTPFVVQQELAEWKRPKIEINGEIREYPRIAGISSFGAGGSNAHVVIEEYMDK
DEQPSSIRITKQNPAIIVLSAKNEQRLKEQVQQMVAAIQQQQISDENLANMAYTLQVGRE
AMEERVAVLVGSSKELEEKLKGFLADQDGIEDLYRGQVKRNKDTMAIFAADDEMQEILKK
WIAHRKYGKLLDLWVKGMIYDWQKLYNDSKPRRISLPTYPFAKERYWVPEAGIAASSNII
SPVTAGLLHPLLHQNTSDFSEQRFSSTFTGQEFFLADHVVKGQRVLPGVAYLEMARAAVE
QAAGVLAEDKIGIRLKNVVWVRPVAALGQPVQVHIGLYPEENGEIAYEIYSDSETVDREP
IIHSQGSVVLRSVTETPRVDLKSLQAECGQSTFTSSQCYEAFRTMGLAYGSSHQGIEVVY
TGQEQVLAKLRLPASVSNTHNQFTLHPSLMDAALQATIGFMLVTGVTGSEASLKPVLPFA
LQELEILSNCPSVMWALLRYSAGSRAGDKVQKFDIDLCDEQGNVCVRIKGFSLRVLEREV
GSVGKIGNNEMLLLEPYWKEQASILETMDSAYVQHVVMLCELSEAYRESVETCMDTIRCV
TLQIEKESIEERFQAYAVQVFEEIQTILKNKQKGKVLIQVVVPTQEERQLFSGLLGLLKT
AQLENPKIIGQMIEVEVEGLSQEIIEILKENSQSSIDNHVRYQGGTRWVNGWREVAVTEE
ISLPWKDNGVYLITGGAGGLGLIFAQEIAHTVKNATLILTGRSVLDEGKQEKIKAIETLG
AFVEYRKVDVADKQAVGDLIQSIQEKFGSLSGIIHSAGVIRDKFMIQKTKEEMQEVLTPK
VTGLVNLDHASKEMNLDFFLLFSSMAGSLGNVGQADYSTANAFMDGYARYRNDMVVSKQR
YGQTLSINWPLWKDGGMHVDKEAEKAMQGMGMIAMETPIGIQALYQGLVACKDQVMVIEG
DVMKLRSFLGLDLIEFDEVDNEFFQSLFEQITKGELSEEQFESLALTRRGR
>A0A077PIN2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Xenorhabdus bovienii str. kraussei Quebec|TrEMBL
MGNNFTGLEVAIIGMAGQFPGADNIRDYWEMLRDGKEGVSRFTNEILKSNGVSEEYYLNK
NYIPAKGVINKPFHFAADYFGINHSDAKKTDPQIRLMIESCWQALKHANIDTETYPGQIG
VYAGASSQWSWFKALNTEFNSSAEQFHVATLNDLSFCTRISYLLNLRGPSITIQTACSTS
LVAVHTACQALQAGECDVALAGGVSITHPHQSGYLYQEGMINSPDGKTRVFDANACGTVF
SNGVGVVVLKRLSDAIEDNDKIYAVIKGSAVNNDGSDKISFTAPSVLGQQNVIRSALDFA
EVTPDQISYIEAHGTGTLLGDPIEISALNAVFKDIQSCAIGSVKSNVGHCDAAAGVLSLI
KSALCVYFKTLVPSIHFEKANPKLELENTPFYVNTETKPWHSSDNELICAGVSAFGVGGT
NAHVVLQEFPMRTETVSVEDLEYEELPNRIEFKPAIAAETTDVLHAEVESDSVFGEDEID
IEGLPQNLLKIFQEYFSNQKISQNDNFFDIGASSLDIVQLHEKINNTYSVNLSISDFYRY
TNCQKMTEKLLGMIGNKSQGQPKKSKVTKKRKVLNNKNRTYQDYPEHAIAVVGMSGRFPG
SKNIQEYWNNLLQGKEGISFFTDDELIDAGISAHTLKAKNYIKAKGIVADSLSFDPTAFG
YTARESQYMDPQFRLLHEVTWQVLDDAGYGNPKYRPVTGLFASSGSNYAWLDLLKEEIQD
TTEQFGVALLNDREFLTTRIAYKLNLTGPAVTVQSACSSSALAITLACQSLQINQCDLAL
AGGVSVVTPIKSGYTYAKGMVNSADGHCRPFTQDASGTVFSDGIGMVALKRLDDAIRDND
HIYGVIAGYGVNNDGHEKAGFTAPNADGQAACVKQSLKMAAIQASDVEYLEAHGTATRVG
DEVELEGIKDALGVTEINARDCFIGSVKSNIGHTNTASGVASFIKTLLALKHQKIPTSCH
GTENKHTSLENTRFRLTDVAADWVSHGGVRTAGVSSFGIGGTNVHITVQSIEEQPASSQC
QAELITLSSKSREGLVKTMAKLGDFLDEEQHLYSLSDIAYTLQVGRGDYDYRTSLVVENV
EALKDALHSLKDSAKFPAALPDQTSGIVFMFPGQGSQYVNMAKDLYQELEIFKTLLDECH
ERLSRQFSIDLIGLLYAGDSEEDSEKLQNTQITQPVIFAISYSLAKTLELLGIEAKAMIG
HSIGEYVAATMAGVMTLDEALKLVAIRGTIMQECEPGVMLSVAAGRDDLEPFLTDKVALA
TVNSPNSCVIAGSQADIEKVQQRLVDKNFRTRLLKTSHAFHTPMMKPGAEKFKAALAEVN
WQKPTKAYISNVTGQWITPSQANSVDYWVEHLCQAVEFHAGIMTCLEKPGLNVFLEVGPG
RTLSTFVKQIAASDANISTLNMMRHPLEAENDRNYLLKLVGQLWMRGISVNWPLLYQNTH
PKRISLPGYQFAGENMVMGASVLATKGVEKASETKIQKNQISEWLYTEAWEDISLPDEAT
QSDIRVALCFVPDIAWCQPLCNSLKLEEKSIKFVLPADAYTSAENVITLVPGDKRHFGKL
IDELKQDALLPDSIIFAWPLSGQSDLETSWFSVITLIQSWTTSGSMTDFRLLLANTKQPE
HTMLNGLVKVITQEVSKCHPRLVQISPLESIERQCEILTEELLATDERFIVNRTQTGRST
LAYHKLKAGLLKENTLLKNEGVYLITGGLGDLGLLFAEYLIKEYGAKVILSGRRALPGKH
EWKHLVSLDHPEAEILQRLDELSELGKGEVAYYSSNVSDKHEMQALLDAIEEQYGCLHGI
ICAAGVTRGNSFQGINKLTLEDCTPQIETKVEAYQILAELTENKPLDFCLLCSSIASVLG
GLSFSAYSSVSSFADAFAKQQNSQGKPWISVNWDGWVFERNNSGDPIGSSLDQLLIEPDE
GLKILECALQSPLRGQLIISTGDLNKRFEQWVGGHLKPFKLNEFNHSQRAVVSKEQIVGT
IVSVWQDFLKVTNISRDDNFFELGANSLDMVQVNKRLTDALDMDFSVVDMFSYPTSELLA
DFIMNQYGITHDTGEQAAHSDTLNQHRDPSAQLNQSSTPIDRQIAIVGLAGSFPGAENIH
EFWENLTFGKESVTTFSKEELSEEGIDSGLLENPNYIRAKGVFPNAGEFDAEFFGYTPYE
ARQMDPQVRALHTCCWQALQDARIATKDNRAKIGLYASASGNLQWLAQAMATAEGSAGQY
SAMTVADKDYMSTIVSYKLNLTGPSMVLSTACSSSLVAVNEAVKSLRAGECDIALAGGVS
ITLPIKAGYVFEEGMIHSKDGKCRAFDIQASGTVFGDGVGIVVLKPLKQALADNDNIYAT
IIGTAINNDGGMKVGYTAPSTKGQVEVIQSALRDANAMAESIHFVEAHGTGTTLGDPIEF
NALKQAFSTDKKNYCRIGSVKSNIGHLNSAAGIAGLIKATLAVKNRILPPTLHYARPNKE
IDVANSPFIVNNQYTELNDTRNPIRAGVSSFGIGGTNVHIVLEEAQVNKDKSFNKKVDNR
LPIVLSAPDDKSLQCYKQQLKTFVENNQHQMSVSDIAYSLMQREPMASQFVASACDYDAL
IKALSSSEKDNVKVKLGTTKRKVVFLFPGQGAQYVTMGHELYHSNGLFKEWCDKGFTLAD
KYCSIDLKSLFHSRDEDRNLYNTEFAQPLLFIIEYALAQVLKSYGVTPDAMIGHSLGEYV
AAALAEVFSFEDAIKMICARGKLMQSTEDAVMLSVMSSSESVKEILIGSLEIALDNSSDL
CVVAGSDSDISSFESDCEAKSIKTKRLRVNKAFHTRYMEPVLGDYASIIREIAFNKPQIA
FISNVTGKWAEADKVVEYDYWVNHIRQPVRFRESITEVLKEGNCLFIEVGPGHGLSTLAE
NHSDYHANHICISCFDRKNEEINKHSELVQKLGKMALLKIDVNWHAEMADLQPRLVHLPP
TPLRGTKYPTDIKRLQALFSGNKNIVYQADKPEEQVSQSKVGSNPHPKAKRSVIDELSAI
WKLILGVDTIKEDDDFISIGGSSLSAVQVIAKAKSIDLPVNMSMLLSGQTLAQISASLQS
DDETTHKGWQFNEHFSPEMYPGSASCLYSAVREKLKHEHGLTSDDAIMQVVDGSPLLGIG
VQQFENDTKIVSKPVNYGTLSGWPSLQECYSFSYDKQFFEDYEAYRHYCESELALGHLVI
VTGSDYYLPFSPSYGLPESEYIKRPLFENIELGDDDIIPHAFVLVGKTPSGYQIYDGSFQ
YFGEITEQEFEKTVIGFKGLDFMQSHEVYNKSRSFMVITVTCDGKFHKDNDLKEQTLNRL
VTDFQTKQAIEGNESHLSYYIGLTALDKLIENPGLIASSSNFDLEEIFSRWYQQMLLLRK
FLKISKPEVSTECDHAFSIISEELEKVVACCKNSSDDKTIIDSLLLVKSNLSDVIKNLS
>A0A222P1A3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Legionella clemsonensis|TrEMBL
MDELGVKPTAVIGHSLGEYVAATVAGMMSLEDGLKLIVWRAKLMQMQKQGAMLAVAVNHD
KAKVLLKTIQDEMSDSILAIAAINSPTQVVFSGEKHAVECLEIICQSQQIKTTALDVSHA
FHSELMQPMIEEFTQLANSITYHKPRIPVISNVTGEALTTIDANYWAKHVLATVNFSAGI
NYLLKKDYRIFCEIGSQPVLLSFAMAHHPNPNEALWLASLKRQQQDWTVLAETLMSIYLL
GGPIEWHSFDKPYAIKSYSKILPTYPFQRQSYWLPIEKYKKSIEENLLERAVYQIGWEEL
ASKAVNANIKSGNWLIFADEQSMDLARQLKSGFENITVINPGSSYSHTQNSITLDPENST
HFKRLFGEIACPVNVIYLWGCQKNLSPVSDKKMFTFIKRACSGLLYLGQALGNKKYIDKI
MIVTRAAVSPFSKKNMPLSAPLIGMCKTLMIEYPELTCQVVDFEAVTPEKEVTTHLLQLI
DNSFTEAIIAVSQNGYYAQRLEPSSLKEDGSCEIDANATYLVTGGLGGLGFILSQWLITQ
GARYIALLGRRELKDVKEQLEALAQEGVTVVYFQADVSHFDQLKNTLLTIQQTMPALKGI
FHTAGILADGLWTNLSWQQFADVFQAKVCGSWYLHQLDSELDLNLQHFILFSSISALLGS
AGQANYAAANAFLDGLAHYRHQLNLPALSINFGPWEQIGMTLHQTQSWLDAGLQNISPSA
GMAALEVMMSSSAAQLSLMPHQLSKENLAAFPLTHRKLLARLIQAKLSSKDARPEHWQHL
IGLESEEQKFHIQEILQDTVKKVLGLTEEKPINPTDTLLSLGMDSLLVVDLLHKLKTRLP
PEINLTAQFLLFENHSIQALITLIHQRLRQLADSDGSNKEQNLVQATDNQLIPLSVQQVR
IWRHIQQQPDNPAYVVAYFLELHGSVDADVLEKSIQAVINRHDMLRCSFQTYLENVFQYC
HKEISFNLERLDFSHLSSMERTLRVDEELMRASHQQFDLTQAPLLKSALIKCTNEQMVWA
ISISHLLADGASSLVILQDILHFYQIFSQQQNHEEMPPATSYQAFINWQLTGLLNGNSAR
YVDFWSRRLKDYKAPCLPVDKSRHDTLPRTGRKEVIPITREQLNALQQMAKQNQTTIATL
LLTIYGLLLANMARTNHAFITVLTSGRDLDEFKTTVGNIANEVPIILRYDSKCSFIELLH
HLQNDFAHSLQYQYFQPEQMAELDLPTPETSFDFQVLKPAQFNVGFTIKPLSLKQTTLPL
WGSNPRKLSMKWTYESTLSGYIKYRSDLYKSETITDLVQQFLQVLEAVIKEPMITCGELV
TLMEEIRVWKI
>A0A086KQL2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii FOU|TrEMBL
MMTRLPLCQQQAPPSLAGCHMLAAFQDIPERPLNRDLKELWAAYGENPFGNVLECWNRSI
PDEDAVVWLNSDGEISETTTFSELFSRITRLSSFLRAAGLQVGDRIILCYPPGTDFVTAF
FACITSGFVAVPVYPPDPSKGLSDVPRFCDINEIAGCKTALTNSLYKRVVQVITTVAKDS
RWRSVHWVCTDDVIKRHAEEAKNSVGPDFPNLSPHHPAFLQFTSGSTGNPKGVIVTHGSL
LHNCHLCWSAYQFPSHYENDGDDENITNHDFALVNQREFWRRRQEISIKSRGHRLRAFSW
LPVYHDMGLIGFVCSPILCGATLYQMSPIDFIRRPWLWLQGMSKYDCICCAAPNFAFEVV
TRKMPDNVYEHLDLSRVCGFLSGAEPIRASTIDRFCEKFGPKGVRRCAVCPAYGLAESTL
IVTARKTFQTVPKLLIVDSFQLQHEKTVVALKPEATVTMDSEEYQVLVGCGVPLEGVQVR
IVDPETKKELPPGKVGEIVVYSSSVARGYFGRPDTTKETFCYSFTDLQGKQTPPLGMRTG
DGGFMYEGELFVAARLKDLIIIRGRNFYPQDIEEAVDKVAMVRPGSSAAFAIEVDGHEAL
AVAAEVRLEEGIKGLWLRVKRQFDRSHYEQIVRDISKSVAANTGLTIHRIWLLRPRTIPK
TSSGKVRRSLTKEKLVSGKLEGILLDHAHHQHQAFYHDGPGGSRSRTRTGSGATPSGGAA
TRDGTASSNPSGDAHPKNSNTSNSITDSSHSVQRGSLRGDACVAGGRLGPSASHGGVHHE
KDHKHRGDGSGMSSPDQVPGAGAAASESSAHVALTEKVKQTVFEAAKTVLGSSEIPEIDA
PLHELGVDSIGAVEFSELISAELQVDVEPTLLFNYPTLSDVIDFFVRELEGKGSEDLAVS
LEKTGARETTTAIIGAACNLPGGTTSLNAFWDLLMCGVDAIAEVPRSRWDVEEYFDPDPG
ADGKAYVREGGFIEDAEMFDAAFFRISPSEAKSMDPQQRLLLEVAYESLYDSGYTREGLQ
RASVGVFVGCCSNDWYQVCSQLELGISSYTTTSYAPSIIANRLSYTFGLLGPSMTIDTAC
SSSLVALHIAAQELQGGSCMSAVVAGVNLMLSPHITVAFCKSRMLAPDARCKTFDASANG
YVRGEGLGSIVMKRLSQAEKDDDRILCILRGTAVNHGGRSASLTAPSGPSQQRVIRTALR
QAELTPGDIYFVETHGTGTSLGDPIEVGALKSVFGASRDAKTKPLILGAAKTNIGHLEGA
AGIAGVLKAMLALRYKHIPPNLHFKQMNPHIDVREFNVVVPTAPMAFPREDGGRLFAGVS
SFGFGGANGHVILQEALQQPSGDKPPCKRHSKRSIICFMFTGEGYEVSCMGRHLYETDDV
FKEIITKCNDILKRWLNVSLLSILYPPADKKMEMDKMMCQARFGHTALFAFEYALAESMV
SKGVKPDVVFGVGLGELVAAAFSGVMSLEEALYVVTQRAKLIDNLPPFEGVMVACRVSEQ
EVEMALSEMEINSRQSISIAAVYGRKNLILSGEQSEIDNVLMKLNIAGRWKYLPVHNVLT
MNLVSDIIPPFTHLMSTVKLCRPKVRLVSSTTGEFVDKEALSGRFWSRQVSQTVQLQQAV
GNIVASGCSLFVEIGPQVVLTKLAQQSLNGNAKDVTWVPAYDTTSDDVRVFENAVMTCNE
AIKIIGKERSLEEGQHGQEELIFHRKPFPWTEIPHPFLSGHKFTEKDDVVFENAFPRRAI
PLIADHAVNGTAMMPGAGMLEMVGAAALALDLRTTSGAVSLENISFERPMLIGAHRVTYE
YNRRHSLGEGGGAGTSPRTVRTPRLVNHAYTRLGFREKSAEKAISETAGPASTEGGRTPV
AGHHHGSYTKAGVLEDIKDYAHNVLRRAAQHAEEIDVHTPVPPSMAPPSIVARHPREGSY
GSMSRTSGIMGSNDRGDGLTVPLSVEMAIRCRVTKMKEVELSTVWDDEVTDHCFATIVIA
DKKQETYSSLQEVRCRCTERMDVNEYYDMLYDAGLQYGPRFRTIQELYRGEKEALARVHF
VGNVKQDPFESGFLIHPAVLDGALQAAGCLLEQSHSGNKVMVPVSVGSATLTKVEVFQPC
WAHVRLEETKSKAATLNVTIYDEVTREVVASLQNAVLRQVDPSASVVATIPKDLLWKVNW
QLVVEGDKEVVGRTPKVLFIGGNIELSEALENAMGSTCKTLSVDALPREKAELQKVLDAE
QWQAIVYVEAVTAGVYDALDVMNAAVRLVQAHYLNLNSGKAVGALWFVTRDTVFRDNGAD
KPGVEIPAHAGLWGLAKAARLEMEVSAGSPISMGCLDVSGADVSSMAQQILHALKSKVLT
MRETEVAVREDGLYVSRLAPQTEVDVRGAIEFHMPERGAISNLVLRPQAFASRLPPEDGQ
IELRVRAVGLNFRDVLNVMGLYPGDPGPPGADCAGVVVAVGDNVEHIEVGDCVFGVAQGC
LRTYVTTDSQLLRRMPESMTFEQAAALPVVATTVEYALHDLAKVKAGDKVLIHAVTGGVG
LVAVQLCKRVGATVYGTCSGGKKDAFAKSMGVQYVSSSRDAKAFAEDMRTFLGEDGKVDV
VLNCLIDDFIPESLKLLGPYGRFMELGKRGVWSKEKVAAERPDVQYELIAVDEMMEKDPI
WFGGMLVRVRGLVAEQKIQPLPMHVFDLADTGENGGVAAFRFMQRAQHMGKVVLKIPSPV
EEASKNGSIVITGGLGALGMVVAGWLAEEGARHICLLSRREEAPQPGEIPGWDWLRTINC
DVQFFSCDVSKYDSIRSVLRTIQTSVAPITGIIHTAGALADALLDSQTPELMKKVYNGKV
QGAWNLNRALEELGLNEQLKLCVFFSSVTSLFGNFGQANYCSANACLDALAQWRRAKGLC
CQSIQWGPWIEQGMAAELKQQVERNGMKGISNEVGLRVLHDAIRQQEKATPVIGCQAIKW
KLFMHRYIEQPPFFTNIEMDLQVTSHDSNTVLRNLPPSERRDYIKAQVAAAARQVLGSSS
PPPFDTPLQDVGVDSLGAVEFRNVLSKKLGVKLSATTLFDYPTLNAIIDHLCEVFGESSQ
KDNLSTKLGALSENDLVQEGMAIVSMSCRLPGNSTCPDLFWDMLMRCTDCVCDIPLTRWN
AEEVYSEDPDLPGKCYTRRGAFIENAEYFDNSFFGISPSEVKHMDPQQRLLLEVAYEAFA
GAGLTKEKLLGANIGVFVGACNHDWTYLIQEDKISAYTGTGSAGSVIANRVSYCLGLRGP
SVPVDTACSSSLVAADFAFEKLMLRDCTMALVTGVNLMLTPHLFIAFSKARMLSPDCKCK
TFDASADGYVRGEGAGAVLMLPYADAKAKQMTIQAVVKGTACNHVGRSASLTAPNGPSQA
EVIRMALRRAGMKPNDLKFMESHGTGTSLGDPIEVNAVRTVFAPGREKTKPLLIGAVKTN
IGHLEGSSGIAGLIKACLVLSRREIPPNLHFKTLNPHINIEDFPVQFVTDFVSLDSVEST
RKKNTAGVSSFGFGGVNAHVLLEEATRDQNATRKEENRPKICFMFTGQGSQYVGMGRHLY
EKEPVFREAITRCVEIAKEYLPLPLLSVIYPSPDERDKMQEAINETLYSQPAVFVISYAL
LELWKSRGVEPDMVMGHSLGEYIAAVCSGVISIQDGLKLVLKRAQIMSRAPSRNGVMVAC
RATAEQVEEAIHTLFGDGEKNVALASVNGLKSVIVSGNQQDVQAVLRQLGAASRAKMLRV
SHAFHSPLVKDTVAPFKRVLETVRLSKPRVMFVSTVTGKVARDELQNTNYWAEHITKVVR
FCDAVQACIAQGAKIMVEVGPRPTLSNMGKGCLPQTTADEVQWINSLEPETLSSAVFDSL
SALAKAGSGAMPAVFDRKFFPWTETCHPLLGGKNTRPDGSVVYSALLRDLVKALFLDHVV
YGKALLPATCLIEMMASATTHMISNHDEEKLVALSQVVFEKPLLVPDETSLSVLVTVETR
GQVRVASQVSNSEEEAEDHAVCQVNIVDALPAAPALTEIRARCKTEIEASQLYAQLHNVG
LQYGPRFQTIVKVFKGEDEVLGLLQAQNVTNFETGFMMHPAVLDGALQLSAVLAFEKGSS
RAMVPFGVDTVLLKSCPPDKELWARVVMNRKGVSSASATVHLYDFDGEPIAVLMGVTLRP
IEFNTAADIPRELLWEVEWESAGSYSMPQDGSLATPSGTDDSGAEDVTRTPSPLVTGENE
NTPSREVPSALPGLSTETPRASKPLSTDETSGAVLNKSVHSVLLVDYAGGHREVVASIRD
TCDVEVEVLSKPGSPELYAQQLRQFAEVVATKTETVPLSTILFLALDEATPAEQLAGGLL
ETVKVFAVEKFKKLPCIWVLTSGAQGPTRSVVSPKHAGLWGLMRTVRLELEMQIGKMVRF
GCVDLDKNLEVSVALHFILQKRTEEPFEAEMILRCPSEDSEKEPGTAEVVNRRERSASFV
SVGPEPVVPSTTDASAKSSVTSDRMALTPGALSCFDETANSTEKLIFNAFCPRLHRSPIP
VRGAVELHMPERGAISNLVLRPQAFASRTAPQSHECEIRVRAIGLNFRDVLNVMGLYPGD
PGPPGADCAGTVVAVGSGVRHLKVGDSVYGIAQGCLRTYVTTNGNLMRRMPESLTFEQSA
ALPVVAATVEYALHDLAKVKEGDKVLIHAVTGGVGLAALQFCKRVGATVYGTCSGGKKAA
YAKSLGVKYLTSSRDASAFAEDMREFLGEEEKIDVVLNSLIDNFIPESVKLLAPGGRFME
LGKRGIWTKAQMAAERPDVYYETIAVDTMMQEDTVWFGGMLDRIRDHVDSGNIPPLPLHV
FEMTDPLAGGVAAFRFMQRAQHIGKVVIRIASDLEVKIPSTTEPAATETAMLAEAGTQGN
ASIGTSTQQIADRT
>G4FN26|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Synechococcus sp. WH 8016|TrEMBL
MEMRKLGDAVRAAGGTPVFDIEYESSPNWRKIIDEAQYHTQHKQLNKKITVKANIRQLED
VKINILNHTDSIEEVIISIDVDNVKNISKAIEGLRVKVILEIDRVSTLESIEKELERFSG
IIVKGNECGGMVGEDSTFILFQKSYKIVKNRVNLFVRGGIGINTAGAFRATGASGVVLDD
QLWLMPESPFLENFKKYFRNVSGQEAIPLGENIGITCRVFSKPGLEAVETLKSLLKSIEE
KNQSSNEEMNEWEKGLMNRIGWGDPKVVAWPIGQTIGLTEVLTNKYKTTYNLVRAYLYET
CSYLTDAILENPLRKDSKLAKSHGTKFPIVQGPMTRVSDTAEFADSVSCGGAPPMLALAM
MKGEQARELLLKTKDLLESRPWGVGILGFAPKEIRDKQLEAVLEVKPQFALIAGGRPDQA
RDLEEKGIASYLHVPAPALLKIFIDQGARRFIFEGRECGGHVGPISSLVLWERMIETVIS
DIDKKYHPEISMLFAGGIHDRISAAFIAALTTKISSKGCKIGILMGTAYLFTKESVSCGA
ILDGYQKEAIKCVNTVNLETGIGHASRCAVTPFANEFKKVRKDMLVDKYSSDEIKDKLEG
LSLGRLRIASKGKIRNESGKFEELKEEKIYNDGMFMIGQAATLRSEITTIDELHEEIIQG
GEEMLIAEQDKSTICRDYGPSSPSNIAVIGIGSLLPGSHRPEDFWLNIQNKIDAITEIPR
ERWDWRIYYDSDKTARDKIYSKWGGFISPISFDPIKFGIPPKSLDSIEPLQLLTLEVVQQ
ALEDSGYADRNFDRENTSVVLGAGGGLADLGQQYATRSEIPRFVENPDIHTWSRLPEWTE
ESFPGILLNVIAGRTANRFNLGGTNITIDAACASSLAAIDVAVKDLESGHSNLAIAGGID
TIQSPYAYYCFSKSQALSPRGKCFTFDQNADGICISEGLAVVVLKRLEDAERDGDKIYGV
IKSVAGSSDGKGLGMTAPKSAGQVRAINRAYKKAGFSPATLGMYEAHGTGTAVGDRTEIQ
TLSSVMRDANAQPKTCSVGSAKTFVGHTKASAGVVGMVKALQSIYYKTIPPHINVEEPID
EIAHANSPIYINKNIKPWFKTSEIPRRAGISAFGFGGTNFHAVIEEYNDSHNDASGGDIW
PFEIITITGKSKTDLIKSVKVLQGYIDNNYFKDLSQASYWSINKYQDISVKECIIAFTAS
SLGELSNDLTNIIEYLQTPDKTILSNKICLNLELRNQKESLAFVFPGQGSQYLEMMQELA
TYMPEIRQAIEKSEKVLSNKDTGLSIKDAIYPPSSYSEVYRNKQKEHLSQTKIAQPSLAV
IETGLYDLLKRLDLNPNFVAGHSFGEYTALYASECIDSDDVVKIASCRGQLMQDSCDKFN
GSMLAVFLEHEQVIERIKHEKNIFVANINSNSQTILSGPSVDLTQLSKKLTEEQVTNQML
NVSGAFHSEYVRDAEEALSTHLEDLNIKSPKVPIYCNSTGGIYPNDKTSIRNLLQKQITS
SINFKGMIEEMHKDGARIFVEVGPKNILSSFIKETLGDKDSFTISVNEKHDSSLAAFLNA
ICNLLSRGVEINLSALFNGRNSTRLDPLNNIIKRDSGITLSGGSCTSNNISKGTNGRISP
LTLEDINENRNKIKSKKQAQQISSESPPDGKILKKPLNQPIAKETRYLNQNLRNTSELLI
AFQSHQETMRKFLAVQESVIGKFLNPSSETNVSHYHDAIITEEDNEILPLSYQINTDVPI
EKTLQVNSLDSEQTITPKPIPISSPPTKTASNIENSEGVNTGRAESLSTLVLTHVSDRTG
YPIEMLDLDQDIEADLGIDSIKRVEILGGLQKEMDTRSVQLITENMEIMTGIKTLRGLID
YLQPDKDSITNSPSSESKLFSQSEQASSTSIDTESIERIVINIISDRTGYPQEMLDVNQD
IEADLGIDSIKRVEILSNIQSALFEENTSLLQENMENMTKLKTISALVSNIQSLLSSAGG
TGLGKS
>A0A0U0ZR53|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus|TrEMBL
MDSAENPIESTPRFAIIGYAARFPGAADAEEFWDVLREGRDAISEVPADRWDAEEFFDPE
PGAPGKVVTRRAGFVEDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGIAPTD
LAETNSGVFVGLATHDYLGMASDELTFAEIEAYMAIGTSNAAAAGRISYRLGLQGPSVAV
DTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSHAHMLAPDGKCKTFDA
AADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
DALKRAGVAPSEVGYLEAHGTGTSLGDPIEAQAAGAAYGIGREANDPLLIGSAKTNIGHL
EAAAGIAGVIKVILSLENELLPQHRNFQNPSPHIPWDRLPVEVVREARPWGRNGRPRIAG
VSSFGFAGTNAHVILEEAPVVSQDAVDAPAPAGGRKFSILPLSARTPAALAQLADQYRTW
LNAHPEAALADLCFTAGVGRAHLEHRAALVVNTREAAVELLGAVADDRPAPGLGRGESHD
TPKTAWLFTGQGSQYPGMARELFETEPVFADTLNRCAAAVADVLEKPLLDVIFDVDGPEA
EEALRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAEVFSLEDGARL
IAERGRLFGSLPAGGRMAAVFTDAERAERLTDEFPSLSVAAYNGANTVLSGPAQDLEKAI
AALVADGVRCDFLETSHAFHSALLDPILDEFEAYANQFNYKTPQRILIDNRTGTALGRSV
KLDGAYWRRHARQPVEFAKSVRTLADMNCKVLLEIGPQPVLTAAALRAWPDPATAPRAIA
SLRRNTADHRQITEAAADAYVLGHLPDFGAFQHGPARKLDLPTYPFERRQYWFSDKRDGD
NRDAGNRQQNSGGPRTEAVRLLEDGKIEELANLLGGVDGDQQTLNVLTKLAAQHNLQRTT
QTIADDRYQFRWEKSPTPLSGSQAAGSVTWLLVGDAAGAAQPLLDVLTARGQQHRALALP
VSDADEAQLVEALRSAAAEDSALRIVHVAALDPGQGSSSTQSLLRIQHQVLGGTRRLFRA
AAAAELRAPIWIVTQGAQHVIEGDAVAPEQSALWGFGRAAALELPQVWGGLADLSDAGAD
EWAQFIGRVSVSGEASTREDQLALRGQAVHVPRLVRREELPSGKPLEVRSDATYLVTGGL
GSIGLEIAGYLAGRGAKHLVLTSRREPGEAAQQRIDALAAQGCEVRAVTADVADGHDVAR
LLAGVQAELPPLAGIVHAAGEIGTTPLSDLDDAEVDRVFAGKVWGAWYLSEAAAGLKLDF
FINTSSIAAVWGGYGQTAYSAANAFLDGLAWRLREQGIAGTSVNFGPWSAGMADAESRAR
LEQRGIKTLSPADALAGLADVVAASGSNAAQGVIARIDWARFLPLYQQAGKRGFLAELDR
EVPSHLAGAAAGGQSGSTQLVERLANAPVQQRKKLLTDYLRDAVAEVTRVDVSEIREDAG
FFDLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLGDVLGLNEQAKPAAQ
LASAVTDRTDEPIAIVAVSCRFPGAPDPEAFWDVLSGGVDAIREVPEDRFDIDEFYDPDP
EVAGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYSPAAL
RGSRTGIFAGVGANEYAHLLSSESIDKIEPYFITGNALNAISGRVAFALGFEGPAVAVDT
ACSSALVAVHQAVQALHSGDCDLALAGGVNVLLSPVTVIAASRARMLSPVGRCKTFDASA
DGYVRSEGCGILVLKRLSDAERDGDRVLAVIPGSAVNQDGASSGLTVPNGGAQQRLIGSV
LARAGLVGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGGSREADRPLLMGSVKSNIGHTES
ASGAAGLIKVVLSLQNGVLPQSLHFDNPSPHIPWESLPVRVVDKAIPWQANGRPRRAGVS
SFGFTGTNAHVLIEEAPQPQATPEEDDASTPQSAPVNVLPLSARSPEALAAVAQRYESWL
AAHPDVDLEDVCLTAGRGRSHFEHRAALVVDSIQTAREGLLELAQNRLRPGVVRGEHTNH
PTTAWLFTGQGSQYPGMARELFDAEPVFAETVTRCAEAVKDIVTRPLLEVMFATDRETGG
KAGEALRHTSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSLEDGA
RLIAERGRLFGGLPAGGRMVAVFSDAKHVEQIAGEFPRVSVGAYNGPNTVLSGPGEDLEQ
AVARFQEEGIRCTWLETSHAFHSELLDPILDEFESYAAQVQFAAPTLPLVCNRTGAVLTA
QTPIDGQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAPPRA
IVSLRKGVEDRRQIADALASAYVSGHRPNFAALQRHPRRTVELPTYPFQRRRFWPKSSGT
AIEGGGGLPSGILGRGEDLASGDSVYISRLSVRSQPWLSDHVIYGTVVVPGATYAAMALA
AVGTPARAKDVFFYEPIILPEKSSREVQLTLHPLEDGSGSKFQVHSRPYGERDVDWSLNA
EGTVVTGIGDDAEPAPEAAEPAEPVDAAIERMERMRPMELFEIFADLELAWGPTWSGSLK
SLWLGEGEAIGDVLVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLP
LRYGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYLDRDGRHLGGIREFTVKRAPRE
ALLRGLGGDATRLLYTLGWHEVPVPPVADEGEESAASVGTWLIAGFDELAAKVPGCIPLN
RETDPELLGEVLVAAKERGVPFSGVVWRAAGPGATESTTESAARLEGEIAHLLSAVHTVQ
NSAQNGVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTINEEPALRAKLVDGDGS
PEAVQALARLLVTPVEEPEIAVRQGKLLASRLLPWSRTGHLTVPRGSDYVLAPTERGAID
NLRITEKEVPAPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGIVTQLGEGV
TGVEVGQRVYGSMQGAFGSRFNVPAQFLAPIPDGISGVEAATIPAAALTVRLSFDWAQLK
PGDKVLIHAASGGVGLAAIQMAQQFGAEVFATASTFKRATLRKLGVKYVYDSRTTDFADQ
ILADTDGAGVDVVLNSLTSEGFIEATLRATAKNGRFAEIAKRDIWSTEQMAQARPDIAYE
IVALDTVMFQEPDRIRVLLTEVSEGLAKGEWRPLPAEIYPLTEARTAFRRMQQARHIGKI
VCQMPNPLAPRPDRTYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRAPDTDAQRVIAEI
TERSKTRIHVFTADVGEESEVVGLLNRIRAELPPLAGVAHLAGVLDDALLGQQSVERFRT
TLAPKAFGAEYLDRLTKGDHLDFFIVSSSVSSLFGSPGQSNYATANALLDGLIAQRRAQG
LPATGINFGPWGQGGMASSEAATANISAQGLIPLDPSAALAALAEVVANGTGQATILKAN
WQRAAKVLGSSRPPILDLVLPSAVGEVTGDSELLKQLMEIPVPQRAGFVTEFLQREVQNF
LRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVG
QLPDAESAEAPPAVESAEAESGTGPAAASDAVSELKE
>A0A378WMY8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia africana|TrEMBL
MSSYRLPDGSVPILLSSDNPDLVGREAAAVADYLADHPDVTPDRVADMLFRTRSPRRHRA
LVMADAQTDVIAALRAVADGRPHPAVVRSERAATAQRVAYVFPGQGSQRPGMGAMLYEHS
PAYRDAVDQCDKVFHDLYGWSPRVYLLEAEQAADDKALTVQPALFVQMVGVAAMWRAAGV
GPGMTVGHSQGEIAAAYVSGAQTLRDAVRIVTTRARIVDDRKLSGYSMAVLGIDRDECED
LIARQADFVELSVINSRHIIAISGERDAVVRIVESFTSAGKFAKEIRVRYPAHTSYVSTG
RDVLAATVGPEMDNHAFIDTEIDCIGATMGDRIHSGLSIVDYWYLNLRNRVRFDLAIRKA
AEGGASTFIEISEHPTLMLAIQENLGEIPGQREFQALGTSRRTAENLREFTRNLATVAVH
DANYRWEALRESGDGGVPALPLLDFPHTQMSAKSLWAPFDYARTVEEATAETESGGPTAA
PQRVVETWTRLQRRMMVPPRTLALVDPSGAHAELAAAVRAAAPRQGATVVEPGTDARPDT
LVVLAPPPSPDGPVHDVSEFLGGRGWLGELDGIGDIWLVTSGGEHVVDSDLPDPFHAAAQ
AGFRCLAAEHVGVAFRHADLGAGTDAAAAAKALLGAIHIAGEPEVAVREGAYYGKRLILD
DTAGDIPPRGEELREVVIVGGTGKVGLDCCERFAAAGAGRITVISRTGGSAAGAARIAEI
GARYESEIVARRCDAGDADALGDLAAEYAASPATLIVHAAVDYEAAAADPNPVTIRAAAG
AKSGVLHNLTRIFPRTVDGRIVVCSSLSATLGGRGHMVYAAVNRMLDAQAAHYRAEGIRC
SSVQWGLWRAVGADHAEALARISGTGLLPMDPAVAVAAGFAPRAGTVLVAAAQWGRIRDL
FSVFGFAPLFAELPDDEPEPVVVTVAEPVAAPEPAADTAAAPRGTADTVRDALRVVMGLE
PDEAVDGSVPLVALGLDSLQALDLRKRVESELRRDLPVTAILGGASLDEVVALLG
>A0A0N1NIG4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MADDERLRQYLKRALGESREAQRRLREVESALREPIAVVSMGCRLPGGVTSPEDLWELVA
AGGDAIAPWPDDRGWDLDALYDPDPDRPGTSYVRHGGFLYDAADFDAEFFGISPREALAT
DPQQRLLLETSWEVFERAGIAPDTLRGSSTGVFVGLAGQDYHTRLDRVPAELEGHLGVGN
LASVASGRISYTYGFEGPAVTVDTACSSSLVALHLAVGALRAGECDLALAGGATVMSTPA
GFVAFSRQRGLSSDGRCRAFAASADGTGWAEGVGLLLVERLSDARRHGHPVLAVVRGSAV
NQDGASNGLTAPNGPAQQRVIRQALATAGLSPHDVDAV
>A0A0N0MSL3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MSEDRLRDYLKRVTADLHRTTARLRELETKDREPIAIVSMACRYPGGVRTPEDLWRLVAD
GTDAISGFPEDRGWDVDSLYHPDPEHPGTCYTRQGGFLHDAADFDPDFFGMSPREALGTD
PQQRLLLELSWEALERAGLDPGGLRASATGVFVGVMYNDYGSRFDVPPPGLEGFIGNGSA
GSIASGRVAYTLGLEGPAVTVDTACSSSLVALHLACRALRAGECSLALAGGVAVMSTPVT
FTEFSRQRGLSPDGRCKSFSDSADGTGWGEGAGLLLLERLSDARRNGHHVLAVIRGSAVN
QDGASSGLTAPNGPAQQRVIRAALASAGLSAADVDAVEAHGTGTTLGDPIEAQALLATYG
QRRDAERPLWLGSLKSNIGHTQAAAGVGGVIKTVMALRHGLLPRTLHVDEPSSHVDWSAG
DVNLLTEPRDWPHTEDRLRRAGVSAFGVSGTNAHVIVEEAEAVEAAEHESGSDGFVVWPV
SGRGEGALRAQARRLLDAVEGTDVPVADVGLALGVTRSVFEDRAVVVGHGDELRAGLEAL
AAGEPAGSVVRGAVTRGRTAFLFAGQGSQRLGMGRELYEAYPVFAAAFDAVDAEVPFGLR
EIVFGDDEEVLNRTEFAQPALFALEVALFRLLESWGVQPDVLAGHSIGEIAAAHVAGVWS
LADACQLVVARGRLMQALPSGGAMVAVQAAEGEVLPLLNDRVGIAAVNGPRSVVISGAAD
AVEEVAAHFRARKTTTLRVSHAFHSPLMEPMLAEFRAVVSELAYARPQLTVVSAATGETV
SADELTSPEYWVRHVRATVRYADAVRVLAQGKVTRFVEIGPDGTLSGLARTVLDDDGRVV
VPVLRKDGPEAAGLLRAVGALHVHGHSPDWSALFPGARPADLPTYAFQRRRLWLDPLPGG
GRRDGGHPLLGSAVTLADSSAVVSTTVLSARTHPWLADHTVAGTAVLPTAAYLDFALHLG
GRVGLHQVVELGQELPLVLDGDASVELQVVLDRPGEGDGTRPFACYSRPVSVDADTPWTC
NARGTLAPARVPATEEQGAGAWPPPGAQALDADELDGIYEELRERGLDHGPAFRGLTAVW
RAGDEVYAEVAVPEEFRADALRSALHPALLDAALHAAAVLGQPGGFAVSWREFTLYAACA
EALRVRLRALPEGGLRLELADEAGDPVATVGAVALTPAAELSLPVTGPAGADLYAVEWAQ
LPVAAWPVELPTVAAVCGAPVPTGAEHHPDLDTFLASLDVPDAAVPELVLVSWPEEDVDL
PSAVHQLTATALETLQRWQADERTADARLVVVTRDAVAVRPGEPVAAPALAAVRGLVRSA
QSESPGRFLLVDTDSESAAEDGEFLAAVTDAIHAGETEIALRSGRAYAARLVRHRTDPSG
SGADVLDPERTVLVTGAGGTVATAVARHLVAVHGARRLLLVSRRGSDAPGAVELRSQLQE
LGAEVTLAACDVSDPGALAELLAAVPREHPLGAVFHAAGVVDDGLIGGLNPERLSAVLRP
KADAAVHLARLTEELELSAFVLFSSAAATFGGPGQGNYAAANAFLEALAAGLRARGRDAL
ALGWGLWAEDSGMTAGLGAADRTRMARAGVEPLPTADALALLDLALAQDRAVLLPVRLDL
AAARAATTPGPALLREPAASVRRTARPARAARTLAALPEPERPAAVLRLLQAEIATVLGH
TADTPAADPQRAFRDLGFDSLTAVELRNALERRTGLRLAPTVAFDFPTPAALAAHLLGSL
PTGDRAPAANSPVSGGANAGTDEPIAIVGMACRLPGGADTPERLWELLASGGDGLTDFPA
DRGWDLASLYHPDPDHEGTSYTRTGGFLPGVGGFDAAFFGISPREALAMDPQQRLLLEVC
WEAVERAGVDPRSLRGSRTGVFAGTNGQDYTTLLSASADDVDGYLGTGNAASVVSGRISY
TLGLEGPAVTVDTACSSSLVALHWAARALRSGECDLAFAGGVTVMSTPAAFLEFSRQRGL
APDGRCKAYGDDADGTGWGEGAGMLLVERLSDARRNGHRVLAVVRGSAVNSDGASNGLTA
PNGPSQERVIRAALTDAGLTPADVDAVEGHGTGTRLGDPIEARALLATYGQDRPDERPLW
LGSVKSNIGHTQAAAGVAGIIKTVLALRHAELPRTLHADRPSRHVDWTSGGLRLLTDPRP
WPRDEARPRRAAVSSFGFSGTNAHVILEEAPSETEEASAGAADQPGGAGITPWPLSARTP
EALRAQAGRLLEHAAHHPESTVADLGHSLAVSRPAFEYRTVLLGTGRDELLAELARLASG
ETRPDETTAAARAGRTAFLFTGQGAQRPGMGSELYAAFPVFAAAFDEVCAHFGADVLDTP
LREAVLGTAGHLLDRTGYAQPALFAVEIALYRLVRGLGVVPDQLFGHSIGSLAAAHAAGV
LSLADACTLVAARGRLMDALPEGGAMVALRAAEAEVLPLLNDQVGIAAVNGPQAVVISGE
ESAVLAVSAQVEALGRRTKRLRVSHAFHSPLMEPMLDEFRAVAAGLEYHEPHIPLISDVT
GAPATIEELASPDYWVRHVRQAVRLHDGLNSLQGLGVTRYVEIGPDATLTALTADALAPA
TDTAAVALLRPGQDEPGSLLAGLARVHAHGADVDWSAATPVSGTVVELPTYPFQRQRYWP
TAAARGTGDLAAAGLADAGHPLLGAHVDLADSGGHVFTSRISTADQPWLVDHAVGGTAVL
PGTAYLDLALLAGHRVGCDRVTELTLVEPLLLAPGQAVALQLRLGAADSDGNRPLGVHAR
PADATPDRPWTLHADGILATEAAATAAAEAAAAPADLDATWPPPGAEELTVDGTYDRLSA
AGFDYGPVFQGLRAAWLLDGVVHAEIALPEQTHAEAPRYGLHPALLDAALHATAFLPWDD
SAAGRLPYSWRDVRLHATGAAAVRVRLTPRGGDAVTLDVADTAGRPVASVGSLTLRAIDP
ERLRARPDRGAGDLFHLDWQPQPADHHPAPATLTILDDRAGREFAAHLAAAGVSADLTTL
SEDSAPATLLAVVPHPDAPLDRAGHEAAQQVLALVRQLLAERRLDGTRLVLVTREALALD
GATGPGVRQPAAATAWGLVRSAQSEHPGRFTLVDTDSTAASLGVLATVVGRSDAQLALRE
GVVHLPRLVRANPDAVLHPPHRTDRAAAWRLDTVRKGTLDGLALVGAPEAERALADGEIR
IAVRAAGVNFRDVLNALGMYPGPARDFGLEGAGVVTEVGPGVREFAVGDRVLGMFPAAYG
PLAVADARTVARIPDGWTFAQAATVPIVFLTAYYALVDLGGVTPGQSVLIHAAAGGVGMA
ATQLARHLGAEVFGTASPGKWDTLRAAGLDDAHIASSRDTDFETAFRTATGGRGADLVLD
SLAGEFVDASLRLLPRGGHFLEMGKTDIRDPEDVAARHPGVHYRAFDLVEAGPDRIGEML
TALVDLFEAGVLTPLPVTPWDVRRAPEAFRYMSQARHIGKVVLTLPAQLDPDGTVLITGG
TGGLGALLARHLVTEHGVRHLILAARRGPDAPGAEQLVAELAESGADVRVEAVDVADRDQ
LAALLAAVPEPHPLTAVVHAAGILDDTVVERLTPERLDAVLRPKLDAAAHLHDLTHDHDL
AAFVLFSSAAATLGAPGQGNYAAANAFLDALAEHRHALGLPGLSLPWGPWAQSTGMTSGL
TDADIRRMERAGLPPLTPKEGLALFTAALEQPSAVQLPLAVDIARLGADGPVPPLLAGLA
RLRRAVADRPAADAPGGSADLAGELARLGDTDRRRRLVEEVCRQVAAVLGHASAARLDPD
QSFKELGFDSLTAVELRNRMNAATGVLLPATLVFDFPTPAVLAEHLRREHFGDSDAPQPG
MGEPDEATLRQLLTSIPLTRFREVGLLEALMELAAAPMSDGGPAPATSNGTGANTAADAD
VDVDDMDVDDLVRMALGADD
>A0A0N1H1D0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MAESDKMDEKYVEYLKRLTAELRQTRRQLREVETRDREPVAIVAMSCRYPGGVDSPEELW
RLVDEGGDAVSGFPVDRGWDVEAGYDPDPDNPGTFYALGGGFLHEASRFDADFFGISPRE
ALAMDPQQRLLLEIAWEAFERAGIDPAAVRGSSTGVFVGAATSGYGAGVSEFPEGVQGLL
LAGNATSVASGRIAYTLGLEGPTVTVDTACSSSLVALHWACQALRRGECDMALAGGVAVM
ATPAMFYEFSRQRGLAADGRCKAFSDDADGTGWAEGAGLLLVERLSDARRLGHPVLAVVR
GTAVNSDGASNGLTAPNGPSQQRVIRAALAGAGLTPADVDAVDAHGTGTSLGDPIEAQAL
LATYGQDRPDEQPLWLGSLKSNIGHSQSAAGVGSIIKMVEAIRHGVLPRTLHVSEPSRHV
DWSAGAVRLLTEPVAWPETGHPRRAGVSSFGISGTNAHAVIEQAPAPEEASSAPELTAPA
VPEVARTLPVVPWPVSARSEEALRAQAARLLARLRQAAEPPTVLDVGHALATTRAALEHR
AVVLASDHDTAVRELAALADGTSGTATVRGRTTRGATAFLFAGQGSQRLGMGSELYEAYP
AFTAAFDAVDAELPFSLREIVFGDDAERLNRTEFAQPALFALEVALFRLLEAWGIAPKFL
LGHSVGELAAAHVAGVWSLADACRLVVARGRLMQALPAGGAMAALQATEDEVLPLLNDSV
GIAAVNGPRAVVISGAADAVEEVAAHFRAQDRKVTALRVSHAFHSPLMEPMLRDFRAVAE
SLTYHQPRLTVVSDVTGETAAPAELRSPDYWVRHVREPVRFADGVRLLAKRRVARLVELG
PDGTLTALAQGCFDADDEGPLAVPALRKDRSEPAALTAAVARLFAHGKPVDWAAVFAGTD
ARAVELPTYAFRRERFWLEPTPLGTPSDTTGAKATDAGFWTAVEGEDIAALADTLDVDEG
LVRPLVPALSSWWRGRRELGRVDRLRYRVGWQPVDRATDAPLTGRWLLAVTDADTPDVPA
ITEALTARGAEAVVWEYAPDEERAELAAQLTDAGTLAGVLALPHADPDAPVDVLLRTVRL
VQALGDAGVTAPLWSATRGAVATARSDTAPRPTQAALWGLGRVAALELADRWGGLVDLPA
TVDRRAAARLATVLAQTGEEDQVAVRASGVFARRLLHADDENVAPGGGWQPRGTVLITGG
TGALGARVARWAAEQGAEHLVLTGRRGPDAPGAAELAATLGELGARVTVEACDVADRAAV
AQLLSRYTVDAVVHAAGVTDSVPLPDLDADRFRAVFTAKAHGADHLDAVLREQGDRPLDA
FVLFSSIAGVWGSGGQAAYAAANAHLDGLAEQRRARGATATSVAWGPWGQGGMAAEDGAE
EFLRRRGLTALDPDTALAALRRVLHQDVTGQVVADVDWTRFAPGFTSTRPSPLLAELPDV
QEALSAGPGVIEEHGGAGAALRERLAGRPAAERARVLLELVRTHAAAVLGHADAGLLETR
RAFRDSGFDSLTAVELRNRLTAETGLALPATLVFDHPTPVDLAAFVQGELAGAVEGDTTG
HRTAATTSGGTRTGGATDDPVVIVGMGCRLPGDVTGPDDLWDLVAQGRDAIAEFPTDRGW
DLDALYDPEPGRPGTSYARHGGFLTGAGEFDPAFFGISPREALAMDPQQRLLLETSWEAL
ERAAIAPGGLRGSRTGVFMGSNGQDYPALLLSTPDAGDGYLGTGNAAAVVSGRIAYVLGL
EGPTLTVDTACSSSLVALHLAVQALRAGECDLALAGGVTVMSTPGAFLEFSRQRGLSADG
RCRAFSDDADGTGWGEGVGVLVVERLSDARRNGHPVLAVVAGSAVNQDGASNGLTAPNGP
SQQRVIRAALADAGLRPADVDAVEAHGTGTSLGDPIEAQALLAAYGQDRELPLLLGSLKS
NIGHTQAAAGVAGIIKMVLAMRHGVLPPTLHADVPSTHVDWTAGAVELLTEGRTWPAEDR
PRRAGVSAFGVSGTNAHVIVEQAAESGRRPRDAEQSPNAGQSSNAGQPPNAGQPLHAGQP
SGVELPASVKPFADAPVPWVISGASGNALREQAQRLLAHVADRPALTSAEVGLALATTRT
TLEHRAVVLGTGREEFLNTLASLAAGEPAPDAVTGRASTEGRTAFLFAGQGAQRLRMGRE
LYATHPTFADAFDAASAHLDAELPRPLREVVFGDDAELLNRTEFAQPALFALEVALFRLL
ESWGVRPDVLAGHSIGEIAAAHVAGVWSLADACQLVVARGRLMQALPSGGAMVAVQAAEE
EVLPLLDDRVGIAAVNGPRSVVMSGAADAVAEIAAHFRAQDRKTTALRVSHAFHSPLMEP
MLAEFRAVAEQLTYTRPLLPIVSTVTGFAATDEEVTSPEYWVRHVRQSVRFADAVRELAA
DGVGRFLELGPDGTLTALTHASLDEWEPVAVPSLRTDRTETVALLSATATLFAHGAEVDW
PAFFRTAVGTEKSTVELPTYAFQHSRYWPRPGGGHFGDLRSAGLSAAGHPLLGAAVTLAD
SGVAVFTGRLGADFQPWLAEHVVSGAVLLPGTAFLELALHAADRVGCAQVEELTLRTPLV
LPTRETVQLQVTVGSPDPDGPRDVGVYSRLAGRPAADDLDDEPWTQHAVGTLLPEPAEPP
ADAGTRPPADATATSTDTLYDQLADTGLSYGPLFRGLDSVHHHGDDLYAEAALPEEAGPD
ARRYGIHPALLDSVLHALGAAAATSTSTSDAATGPGLPFSWTGVTLHATGASRLHARLRV
TGSGAVALDLADPSGAPVATVGSLTLRPLTAQAQPTEPAPTGHAELLHRVDWTPLPLDEK
DGKTAGAPAYENAASLPTSLPDSGVEPGADALIRVDAQAGDPAPTAHTLTTHVLDLIRTW
LTEERFEDARLVIVTEGAVTLDETVPDPALAAVWGLVRAARAENPSRFALLDVDATDASW
AATAPALASGEGELAIRAGVAHTPQLGRAASGAELAVPAGESAWRLDIVEKGTLEGLALT
AAPGVGDELTAGQVRIAVRAAGVNFRDVLNTLGVYPGDAKDFGLEGAGVVTGVGPDVTEL
AVGDRVMGLFPYSFGPVAIADARTLARIPVGWSFAQAASVPIVFLTAYYALTDLGGVRAG
ESVLVHAAAGGVGMAATQLARHLGAEVFGTASAGKWGTLRELDLDDAHMASSRDTAFEAA
FLAATGGRGMDVVLDSLAGEFVDASLRLLPRGGRFLEMGKTDVRDPDTVAAQHADVMYRA
FDLWEAGPERIGEMLADLVELFNSGVLQPLPVTCWDVRRAPEAFRYLSQARHVGKVVLTV
PAPLDPDGTVLVTGGTGGLGALVARHLVTEHGLRHLLLASRRGLDAPGARELVAELAELG
ATADVAAVDVADRDQLAAALHTVPADHPLTAVIHTAGVLDDGVVASLTPERMARVMRPKV
DAVANLHELTRDADLSAFVVFSSVAGIFGGAGQANYAAANAYLDAFAVARRTAGLPATSL
AWGPWAPGAGMTAELTDADLRRMARGGMRPLAAEQGLGALDAALGRSEAVLVPIALDRRV
LRDRQAVGALPAMLRGLAVAPARRAAAVVDGGQAGDGFRDRLAQLAAAERESAVLDLVRA
QTALVLGHAGPDAVEASRDFRGLGIDSLTAVELRNRLNAATGLRLPATLVFDYPSPQALA
RHIGGELQLPDDTAPLARAASPVAPTTADDERIAIVALGCRFPGGANSPEKYWQLLADGV
DAVGAPPADRGWQADGIEGGFLYDAADFDADFFGISPREALAMDPQQRLLLEISWEALER
AAIDPRALHGSRTGVFVGTNYQGYGSAAHAVPEDAQGQSMTGHAASVASGRVAYVLGLEG
PAVTVDTACSSSLVALHWAAQSLRSGECDLALAGGVTVMATPGAFAEFGKQGGLAGDNRC
KAFSDDADGTGWGEGAGILLLERLSDARRNGHPVLAVVRGSAVNSDGASNGLTAPNGPSQ
QRVIRTALGAAGLTSADVDAVEAHGTGTSLGDPIEAQALLATYGQDRELPLLLGSVKSNI
GHTQAAAGVAGVIKTVLAMRHGTLPRTLHLNQPSTHVDWTAGRIELLAEQRAWPETGRPR
RAAVSSFGISGTNAHVVLEDGGPAEVAARSDALGPFAWPVSGRTPAALRGQAERLRAHLA
ARPELAPADVAHSLATGRAVFEHRAVVVATGRDELLAGLGALGRDEDAAAVVRGRSGSAG
RTAFLFSGQGSQRPGMGRELLDRFPVYADAFRRVCDGFAPHLEVPLDDVVLAEEGTERAG
LLDRTAYTQPALFAVHVALYELVRSWGVTPDALMGHSIGELSAAHVAGVLSLPDACALVA
ARGRLMEALPAGGAMAAVQASEDEVLPFLDEARVGIAAVNGPDAVVVSGDEDAVSDIADH
FAGLGRKTRRLRVSHAFHSAHMDAMLAEFEEVARGVRYAAPAIPVVSNVTGEQATEAELT
APAHWVRHVRQTVRFADGVRSLRADGVGTFVELGPDGSLTALALDTLDGLADQEPAAHAV
PVLRRGRPEAVAALLAAGALHVRGLAAAPADPARTVELPTYAFQADRYWPAPAQTSSAVG
DGDRVDDEFWAAVERGDLGALTDRPDLGDDTTVGELLPALTSWRRRRREASTADSLAYTV
SWRPVPDASVAPVLSGAWLLAVPADLADDPWTRTIADGLTARGAHVVPFAVDLATADRTT
LAEQLRKLLELDTDTEPELAAVQGVLSLLALDEASIASDGKTAKGTGEETGEETATPAGL
AAFLALTQVLGDLEIGAPLWCATVGAVATTDREGVNSPAQATTWGLGRVAALELAQRWGG
LVDLPADLDGRTVERLAALLSGATGEDQTAVRPAGILARRLVHARPYDGTDAPKRTGGPE
HRTGGPERTGAPERTGAPEWTGAGETVLITGGTGALGARVARRLAERGARHLVLVGRRGP
DAEGAEELRAQLAATGAEVTLAACDSADPAALAALLAKLPVDAVVHAAGVLDDGLLDSLT
PERLEAVLRPKLAAARNLDRLTRDRDLSAFVLFSSVAGTIGSAGQGNYAAANAYLDALAV
RRRAEGLPATSVAWGPWAGGGMAAGGPDAEARLRGAGVVPLDPDAALAALDRAVVRTDTA
AVTVADLAWDRFVPGFTAVRNAPLLAELPEAQPLLKQAAARDEDTAGGGGLRTRLAGLGE
AEQDRLVVQLVRGHVATVLGHGSADAIDADRAFTELGFDSLMAVELRNRLGVAAGLQLPA
TLLFDQPTPRVLARHLRALTATDNGTAPALDALDRLETALAALTEDDTQRGRIASRLLAL
ASRWNGGQDATPAESAGEDAAETDLKDRIDAAGAEDLFALIDNDFGIS
>A0A0N1GAA3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
GVAGVIKMVLAMQHGVLPQTLHVDEPSSRVDWTSGAVEVLAEERAWPETGRARRAGVSAF
GVSGTNAHVVLERPLPEPVLSGSDADAEPSLVLSLVPWVVSGRTAAALRAQAGRLAEFVA
GDEGLSAAGVGGSLVRSRSVFEHRAVVWGADRAELLRGLEAVAGGESAVGAVTGEVGEGG
RTAFLFAGQGSQRLGMGRELYDEYPVFADAFDAVCAYLDTELPRPLREVVFGGEDAELLN
RTEYAQPALFALEVALFRLVESWGVRPDVLAGHSIGEIAAAHVAGVWSLADACRLVAARG
RLMQALPPGGAMVALQAREDEVLPLLNDRVGIAAVNGPQAVVISGAADAVEDMAAFFRAQ
GRKATSLRVSHAFHSPLMEPMLAGFRRVAESLAYEPPQFAVVSTVTGELAAADELTSPEY
WVRHVREAVRFADAVRVLDGQEGVRRYLELGPDGTLTALAQSVLERANDDRDLADGRGPA
DVRDTADGREPAVLVAALRKDRPEARSVLAALAGVFVSGGGVDWSSLLPAVPWVELPTYA
FRHQRFWPTVGGSETGTTSGGSGGSGGEVDARFWAAVEREDLESLAGELELGADVVGAVL
PALSSWRRQSVERAALDGYRYRVDWAPLGGVPRAAVLAGRWLVAVPDGFADDPWALSVRE
ALTVAGAEVEWWTCDPSAGRAELASRVDELGVSVAGVVSLLALSEEPPSEGGVPLAVSAS
VALVQALGDAGVTAPLWVLTRGAVAAGQPGGGVVEPVQGAVWGLGRVAALEAPGRWGGLV
DLPAVLEGAVGNALAGVLGGLGEEDQVAVRASGVFGRRLGRVTGISGEEVGGWRARGTVL
ITGGTGALGARVARWVVAEGAEHVVLVSRRGLEAPGVGELRDELTGSGARVSVVACDVAV
RAAVEELLAEYPVDAVVHAAGAVVNLPLDQVSLGDLGAVWSGKVAGAVNLDAALGDRALD
AFVVFSSIAGVWGSGGQTGYAAANAFLDGLVEARRARGLAATSVAWGPWADGGMAADAEA
VEALRRRGLLALEPGRAVRALGRVVPGADALTVVADVDWSRFAPAYTSVRPSVLLSTLPE
ARTALATVPVEEAEDAREAVLRQELDGRSADERRQVLVDLVRRRAAEVLGHGDTGAVGSA
HAFRDLGVDSLTAVELRNRLAAETGLKLPSTLVFDYPTPRHLAAFLDDELFGATAADTES
ALVTELDRLAATISRLSPENGSRTLAKARLRSMLAELGDQTEGDPKAAVSQQLEAASDDE
IFDFINRELGRS
>A0A0N1NK14|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MELVLRVGDVVGCGTVAELSVDNPLAVPERGGLRIQVRVHEADESGRRRVTVSSQPESQP
ESQAEDGGGAWTRNVTATVIVTATDTVEPSDWPDAEVRHIDVALPPTEQQPLGEAPFLIH
PALLENVWSVLAAGAGLQATAWLAVRLHATGAESLDVQLLPTGEPDTYAVKAVDAAGVTV
LTAGSVALRPVTPQGAPDLLYRVTWTPLATDAATSPAGPPVPWSAVAALRADAEVPGTVF
LPCPAPTGDPQADVRSAVHEVLDVVQAWLADERFVDSRLVVVTRGAVAVSDDDRGALDPA
QAAVWGMLRSAQAERPGRFVLLDLEDREDVAKDVAKGVADDGIDPALATAPTLTTDEPQL
ALRNGQLYVPRLARATTPIPASTPSSPLPPQGTVLLTGATGGLGRLLARHLVEAHGVRHL
LLASRRGPAGADGLEAELAELGARVTLVACDVGDPEAAAELLAGVPREHPLTAVIHVAGV
NDDALVSTMTHQQVERVFRAKVDAAVNLHELTKDLDLSAFVLFSSASGIFGGPGQANYAA
ANAFLDALAERRRAAGLPAVSLAWGLWDETGGMGGRLTSVDRRRMARAGMGALSGADGLA
LFDASFDPALAPDDAVLVPANLDLAALRATAGSGTGTGTGTVPALFRGLVRITAGPVRAT
AGTAGMSAAGAGGATAGLTERLAGLAAAERERLLVAMVRTQVAAVLGHASATSVDVDKGF
LELGLDSLTAVELRNLLGAESGLKLPTTLVFDHPTVRAVAAHLDRSLLPASEHRPLLAEL
DRLESSLAAVDVDADTEREVTARLEALLDRIRLTTATGPVSPTADDATPLDLESASLDEV
LEFIDDEFGPA
>A0A0N1NH58|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
DALAQRRRAVGLPAVSLAWGLWAERSGMTGHLDDADLSRLARGGILPLSSAEGLALFDAA
GRADEPLLVPVRLDPAAIGRQPGPVPPLFRGLVRTTTARRTARTASGDGQHGSNELARQL
AELSSVERERVLLELVRAQAAAVLGHADAGAVGAEQAFREIGFDSLTAVELRNRLNTATG
LRLPATLVFDYPSPRVLARHLRSELVGEENGDDARQPERALSAPTAVAVDEPIAIVGMSC
RFPGGVASPDDLWRLLQDGTDAVTGFPEDRGWDLDSLYHPDPENAGTSYTRQGAFLRDVG
AFDAGFFGISPREALAMDPQQRLLLEATWEAFE
>A0A2X2MRS0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces griseus|TrEMBL
MGVEESGASTVVGSLRREDGGAQRFVTSLAQAFVEGLPVDLGSLVAASGDTVDLPTYPFQ
RSRFWLESGELPASAGVPRDEVEDRFWEAVEREDLESLADSLDLDGEELRPLLPALASWR
RAGRQDSVIDSWRYKTAWRPLTDLGDDDGSALSGTWLVVSPAAEREGATTPALVRALEDR
GADVRLLEVSAGDADRTALATRISEAADGDVPFSGVVALWGLDDVPHPDFPALTGGSLGS
LALLQALHDLGAEAPLWLLTRDAVAVSDSDGLSGAAQAQLWGWGRVAALEHPKLWGGLMD
LPAVVDERALRLAVGALAAPSGEDQIAVRAAGVFGRRLVRSALVGRAPGRTWTPRGTVLV
TGGSGGIGGHLARWLARGGAEHLVLVSRRGKDAIGAPQLAAVIEELGARVTFAACDIADR
DALAALVREVEADGPPVTAVVHAAAHIELGMLADTTPGTLSEICRAKVLGAENLDAIFAE
RDLDAYVLFSSIAGFWGSGDHGAYAAANAHLDTLAERRRARGLRATSVAWGIWDAANDWD
ERNTEMRALKNEKSSRHGLPLLDADAAFTALRRIIDHDETVVAVADVDWDRFVALFTMAR
ESALLAEVPEAARALAAPEEEAAPAVGGDLARRLEGLSRPEQDHLLLDMVRAQAAAVLGH
GPQAESVDAGRAFREMGFDSLTAVELRNRLAATTGQKLPATVVFDHPSPVELAERLRVLL
LPDDASAQPLALVRFGDFETALAAAPPDPATRQQLARRLQGLLWSWSEGDGPAAGAPAAH
ADDTAPVDVASASADELFDLIDRGLGAS
>A0A0U4CTX1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Aeromicrobium erythreum|TrEMBL
MNVGRDDDRGGQAAGSTVEARLRQYLKRTLGELESVTAELDEVTAQSREPVAVVGVACRL
PGGIDTPEQLWQVLVSDGEAVSVAPADRGWPTGPGERRGGFLDDVAGFDASFFGISPREA
LAMDPQQRILLEVAWEAVERAGLDPRSLRGSATGVFAGVGASDYGPRPDEAPDELLGYVG
IGNASSVVSGRVAYTLGLEGPALSVDTACSSGLTATHLAVQSLRRGECSLALAGGVTVMS
SAGAFTEFESQGGLAADGRCKPFADDADGFGLAEGAGVLVLQRLGDAQRDGRRVLAVLRG
TAANQDGASNGLTAPSGPAQRRVITEALDQAGLRGVDVDYVEAHGTGTRLGDPIEAHALM
DTYGPGRTAPLAVGSVKSNVGHTQAAAGIVGVIKTVLALQHDWLPASLHAENPSSQIDWD
DRLEVVTRGRAWERGARVRRAGVSAFGISGTNAHVVLEEGPVAVEPEVDAATTRPATPAP
TTTAPVTAARRSVPLMLSARTPQALRAQARRLLDADVLAADAPVVPVAASLLHRRSRLEH
RAVVVADDAGSARVALGRLADGQPSRDVLLGRGRDRRRPAFVFPGQGAQWVGMGADLLEH
STVFAEVMRECDRALAGHLDVSVLETLRSGSPLDRVDLVQPALFAVMVSLAEVWRDSGVQ
PSAVVGHSQGEIAAAHVAGALDLETAARVVALRSRVLRGIAGRGGMVSLATTPDDASRRI
APFGDALAVASVNSPRAVVVAGDPSALDDLLAQCEADGLRARRIPVDYASHTAHVESLRD
DVLRELRGVGATTGRVPLHSSLTGAPIDTSTMDADYWFRNLRGQVRFAEAARSLLAEGTD
ALVEVSPHPVLTMALEQVVEDADADAAVLGTLRRGEGGAPDLVRALAEAHVAGLPVDWSR
ELPREAATVELPTYPFQHERFWLETPLAGARTGGPADDWRYTVQWERTEVADVPVAGRVL
LVASDSAAHEVDAVQRAVEQRGGLVEVVRPDDVEASWGRSGVDGSPTLGVVALPHDGDER
DPLAATEALGALVRSWSGAQDPAPLWVVTRRASDAGGSTVDPAQSAVAGLARVVGLEHPQ
GWGGHVDVDDLDDDAAGVVAAAVAAAGPEDVLAVRGTDVWAGRLTADPVPQEPRPWTPSG
TVLVTGGLGAVGRHVARWLARSGAEHLVLLGRGGERGEAAAELRAELGALGVGVSVHACD
VADHDALAAVVAAERAEGRTVAAVFHAAGTSTTTPVVALEPAELRRVAAAKVQGTLNLAD
LCDEASTLVLFSSNAGVWGSPGLGAYAAANAFLDGFARSRRGTGVTSVAWGLWAGETMAG
VEGNTYLKGQGVRAMRPEHAIAGLETALTRGDTCVSVVDLDLDRFVDVFSAARRRPFLDR
LAPAAPKAPQAADAPAADLLVGATTPEERRRRLEVVVHREVVGVLGLDEHAAVDRHVAFR
DLGFDSMTAVELRNRLAEVTGLREGVTVVFDHPTVHRLAQHYLDRLREGSADEVAQTPGP
LGVPSAPSTEEDPIVIVGMACRLAGGVRTPEDLWDLVARGGDAVTDIPTDRGWDPDLLAG
IAETSEAETMRGAFLDGAADFDAAFFGISPREALAMDPQQRQVLETTWELFENSGIDPRS
LRGTRTGIFLGAAYQGYGRDADVPQEAEGYLLTGGSSAVVSGRVAYVLGLEGPAITVDTA
CSSSLVALHLAVGALRSGECELAVAGGVSVMAGPEVFVEFSRQGALAADGRCKPFSSAAD
GFGFAEGAAFVAVQRLSVARREGRRVWGVVAGSAVNQDGASNGLAAPSGVAQQRVIREAW
ARAGVGAGDVGVVEAHGTGTRLGDPVEASAVLATYGRGRGGAGPVLLGSVKSNVGHAQAA
AGVAGLIKVVMGLSRGVVGPSVVVGSRSELVDWSAGEVELAEGLRAWPVGPDGVRRAGVS
AFGISGTNAHVVVEQAPAQETSDDEPVGAPVDEDGVGSAATSGSGAGVLAGGVVPLVLSA
RTPRALARQAARLRDALAGTDALTLPEVAWTLATGRAHLQRRAVLLPRDVVHARALLDDL
AEGRTSSEVVVADARTAEPVMVFPGQGAQWVGMASGLLGVEVFASALAEVDVALGEVLGF
SVREVLEGREGAPSLDRVEVVQPALFAVMVSLARWWESVGVRPAAVVGHSQGEIAAAVVA
GVLSVADGARVVARRALALRALSGGGAMASVALPVERVRAWVEQVGGLEVAAVNAPAQVV
VAGDVAAVEALVEQGRREGVRVRRLAVDYASHSVHVERVREALVGELGVVQGRAGRVPVF
SSLRGARVEGPELDGAYWYENLRGTVRFDAAVRAAMDEGHEVFLEVSPHPVLAAAVQETA
PDGLVLGSLHRERDEHLLHELARAHVHGVEVDWTALLDRTLPARLPTTAFEPVRYWLAPE
PADRSVGDRYGIVWRTVAEPSVPDPGAATLLTLGEPPADLEKVLQGVGTRFVPLDLADPQ
DVAGAAGVLSFGGGAAEQLDRVQRFLACDVDVPLWCVTRGAVAAAEDDLVDPDAAMVWGL
GRVVGLERPERWGGLLDLPAEVTADDTGALLAALLGDDLEDQVAVRQGRRLCRRLMAAPA
DRSRRRWWPGDGTALVTGGTGALGAHVARFLVAQGVRDLVLLSRRGPHADGAQELVEELR
AAGADATVVACDVADRGQLTSVLDRLRSEGRRVEVVVHAAGAPDARRLEDVDRPEEVWRA
KVEGARLLDELLPDVSSFVLFSSGAATWGSAGLGAYAAGNAFLDGLAQRRRSEGRAGTSV
AWGAWAGGGMAGADLDGLRRRGIRPMRPERALEGLRRALEQDDVCVSVADVDWARFAVGF
TAARPRPLVADLVPDDPELPTSRTAAPAAQAAPTTAEEAVHLVRAQMARVLGHARADDVP
ADQPIGELGFDSLSAVGLRNELQRATGVELPATVVFQHPTPRALAERVLELGRAAGSPTP
SAAGGSLVEGYRRAAESSRVRPFLSLMADLAEFRERSADPDVLAENVVPVALGTSGDGPV
LVCCAGTAAPSGPHEFARLAAALDGSWSVLGLPQPGYLAGEPLPASMEALAAAQAATVLR
AVAARPVVLVGHSAGGLMSHALATALTQQGHRPDGVVLLDSYPPGRQDAVEGWIDVLTRR
LLDLETVPLDDTRLTAMGAYDRMLGGWVPDDQQVATLLVRAVDPIAAWPDDDWRASWPFA
HATADVPGDHFTMMQEHAGQVAARITDWWEAR
>A8LFZ9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. (strain EAN1pec)|TrEMBL
MATSHDTLVEALRASLLENERLQRENDGLRRENVQLSEPTRQTPVREPVAIVGAGCRLPG
GVTSPDDLWRLVDEGREGLSPFPTDRGWDLEKLFDPDPTRPGTSYVRTGGFLDAAAFDAG
FFGIAPREALAMDPQQRLMLEVSWEAVERAGIDPTSLRGRRVGVYTGVMYHDYATGVTDV
PPELEGLLGTGNSGSVVSGRVSYLLGLEGPSVTVDTACSSSLVAVHLALRALRAGEIELA
LVGGVAVMAQPGPFVEFSRQRGLAPDGRCRSFAAGADGTGWSEGAVVLVLERLDDAHRDG
RRVRALVRGSAVNSDGASNGLTAPNGPAQQRVIRQALADADLTTQDVDVVEGHGTGTPLG
DPIEAQALLATYGRRPAQHPLWLGSLKSNIGHTQAAAGVAGILKIVAALEHAELPRTLHA
DVPSDQVDWESGAVRLLSEARPWPARDRPRRAAVSSFGVSGTNAHVILEQAPEPPPGAGE
PPPGVPSTAGELPDGDGRPAGAGAAPAAWVVSAASRTALRVLARRVETALHEQPHVPVDA
AGAALRTSRATLRHRAVVIAEDRESGLAGLAAAAAGEPAANLVTGSADVDGQTVFVFAGQ
GGQWAGMGAELLDASPVFAEEVALAGRALARHVGWSVEDVLRQVPGAPSLDRVDVVQPAS
FAVAAGLVRLWESVGVRPDAVVGHSQGEIAAAYTAGALSLADAAAVVALRSQAIAGGLTG
RGGMAAVALPVPAVAERLAPFADQVELAAVNGPASVVLAGEPAALDELVAAFESEGIRAR
RIPVDYASHSRQVERISGVLIQALAGLDPRPPRVPFFSTVDAKWVEDAELDGGYWYRNLR
CPVRFASATRSLLDGGYRVFLEVSTHPVLAPAIAETVDQWDGPPVAVLESLRRDDGGPDR
FTRSAAAAFVRGVTVDLAGASHAAAHDGLAGTADGPAGTGDRPVPSGGGAVELPTYPFQR
RRYWLASTGAGRPSGTPRPGGRGGGLEVDSGDDHMTGDVTRDISARLPAGSEAGAAQDAE
PEPAGSENAGPGDSGLENAETDDAGQEFRARLAELPTAERPARLIELVRAQAAAVLGHAD
TDEVGPDSAFFDIGFSSLTAVELRNRLAAATGLTLPAMLLFDHAVPREVAAYLLDRLEVE
TRV
>A0A3R8ASU3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii CAST|TrEMBL
MASDLTQALLSCLEAVTEPDSEDTPNQRTDAEYRFCAVRQDDITFAEFLNRVSVQFEVPI
GPLAAKDYESFSSFVFHICELKKEKQVNVKTSSHHIINRTNRYSTENEKASISIVGIACR
LPGNAKNPGDFWTVLVEGIDAIVPIPSKRWNHKEFSEGHSERGTIYVKEGGFIDGIEKFD
NGFFKISSSEARRMDPQQRMLLELSHEAFESAGLQAITDDNHKFGVFVGCSSSECLMLVP
EATVALCAAGMLALDSRCRPFDAAANGYGRGEGAVVFLLERQMYSPESRCKQKSLATIRG
HGTNHNGRSVSVTAPSDVAQKKLLEGVLRTASVEPQQVAYLEAHGTGTKLGDTIEFRAIK
SVFSTSRSVDNPLLIGSGKSNVGHLEGCAGAVGLLKALLVLYFREVPPTLHFKKISPLID
DEGFDYQIPTKRLTLAGDRPILAGVSSFGLGGCNAHVIIESVPKDREMDALSLSRRHIWD
HMEFPVFESADDGNSFGGLAMRHNVDLCNSTCNHLRRRSTSSLIGKCTLTPVSARLRRFT
AFSSGDGTPGLRVQQYGTTEGSSKANEPHAITEKQISRWTRDNRKGLYVEVESMKDELER
SFSLEDDNGSVQTEQTEPDQMANEVVNTVDEEAVQTLVLQTVRQILKEAVSIHRDVSLKT
LGIDSLAAVEFRDSLQESLGISLPASLIFDFPTIDDVCRFLAQKLQSGDGGERRNTPTNL
AQPRPSTSSETCVAVRGMSCRFPGAEDGTTESFWEMLHSDSDCIQEIPTSRFDAASIFDT
DYDARDKIYVKAAGILRGADMFDNTFFKISEVEVRHLDPRQRILLEVAYDALVDSQVLGD
QGLAAIDNEIVGVVIGCSGNDWNTFLQQHALSASSFSGPGTSPALLSNRVSYSLSLRGPS
LTVDTACSSSLVAIDIARQLLNASQCNLALVGGVQLLLTADTFIHYCRARMLSPDCRCKT
FDASANGYVRSEGCGVVLLENTHDRQVSKNTTYAWLLGSANNHVGKSASLTAPNGPAQQA
VILASLRSAHLQLTSQIHLIETHGTGTSLGDPIEIGALQAVYGQGTSADTPLVLGALKSR
IGHTEGAAGIAGFIKLICSLRQRIAPPNLHLKTFNPHIDISTADSSRPFLFPTKAYPLDT
LMAGEKTEALLGAV
>E0I6D4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Paenibacillus curdlanolyticus YK9|TrEMBL
MNKHVQAREPIAIIGMGCRFPGGASDPQQYWEMLRAGVDAITEVPSDRWSISSYYDPTRS
KSGKTAAKWGGFLDKIDEFDARFFGISPREASMMDPQQRLLLETCWEALEDGGQIVSEMS
GSRTGVFMGGFTLDYQLLQFSEHNRHLVDSHSATGTMMTLLANRISYAFDFRGPSMALDT
ACSSSLVAVHMACQSIWSGESAVALAGGVNVMLKPDYFIALSKPGMLSADGRSKTFDASA
NGYVRGEGAGVVVLKPLSQALADGDPIHSLIRGTAVNQDGSSAGITVPRGEAQEALMREA
YERAGVAPYEVQYVEAHGTGTAVGDPIEASAIGNVISDLRPDDQACYIGSVKTNIGHLEA
AAGIAGLIKTVMSLKHKEIPPHLHLKQLNPQIKLQALKLRISDKVTPWPRTNGQAIASVN
SFGFGGTNAHVVLEEAPVRATEDTQANRQHSAYLIPVSARSEQALAANANALKSAVASQL
ERPEMSLDDIAYTASKRRDQHDHRLAVVVRSKEELVESLEAFAANEARQGMIAGHAGGSA
KNDEGHALPKMAFVFTGMGPQWWAMGQQLYREEPVFQKVLDDINALLTPYTGWSLLEEML
ADEAASRMGDTEVAQTANFALQVGLVELWRSWGIEPDAIVGHSAGEVAAAYIAGAMSLQE
AVRVIYHRSRLQQKTTGQGKLVAVGLPMEEAVELLRGYEDRISIAAINSPHAVTLVGDPE
ALEHVVVPLQARDVFCKYLRVNVPYHSHYMEPIKSELFDKLAALELHPTTLPLYSTVTGA
LIEGSQLDEGYWWKNVREPVYFAAAAQELLKDGYSMFVEIGPHTVLTSSIAECAAKLDCQ
ATIVSSLRRGEPERGTMLTALGALYTIGYPIAWANVYPNGKHVKLPAYAWQRERYWLESE
ASELDRVGVENHPLLGKRLPAPYPTWEKVIDADVLSALSKAYLQCQNTLPAAGYIEMAVA
AARSLVDDSSAVVQIEHIQFKQPLFLTDDASVKLRFIIDPTDATFSVYSASAPAYSQWLL
LTTGKLRTAVQSSEKIVNMPTLLNQSILFNLEHARSTTLIKEIRRSCNEALAFFEIPSSV
MQEIDALEVHPAVLDSSFHVLSEAMTCTQLANGQHEQSRYLPFEVERLVIHQPMERCMWV
HAKVEEQDAKSIKGDIQLLGEHGQLILEIQGCHAVLMEQEEQEPGREQQLYAIQWVQQDR
QLPREAAMASQTEGDGNWLIFMDAQGVGQSLMDRLHAQGERCIAIWASESASFEQDGNTY
AIDPNQPAHFEQLFNGVFRSSKAACRGIVHLWSLDAEHAVTPKSLLASEALTVNTALHIV
QTVQKWAWHSKPQLWLVTREAQSTDEVTALNVSQSTLWGLARSLGHQEHGDIWGGIIDLD
KQQASADAAFIWEEIWHADEDDQIAVRNGKRYVARLLPVEKRPNPIPLAFRSDASYIITG
GLGDLGQLVAKWMIKQGARRLILIGRTALPPRSAWHEVDKTSAQGRRIAAVRQLERLGAS
VHVASLDIAEESELHAFLHQFEREGWPAIRGVIHAAGVLQSKLVTQMSADDFRTVLRPKA
LGAWNLHHYFKDQELDFFAMFSSIASVVVSAGQGSYASANSFLDALAHHRRSLGLPAYSI
NWGPWEELGMGTIEMAEYMKKRGFTPIQPDQGLEALEQILGQGLPQVMVVAADWPTVQER
NYPMGASPVLLKDLIVEKTEDAQAAETAVALTGKITDLLQQETEPEKRQQLIVGYVQQMS
AKVLRLSSQQLQQDQSLIDYGLDSMMAIELKNQMEKDLSVNISVADLLRGSTVAKLSEKI
GQQLEADAAEQAQALITR
>I7G359|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)|TrEMBL
MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPD
PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS
LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV
DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA
AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL
EAAAGIAGVIKVVMALENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG
VSSFGFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWL
RAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEA
PKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGD
TESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGAR
LIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESA
VATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRS
TRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVL
ASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAI
DRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQRS
THVDPDARYEIRWDAIASAAASTGAAADWILVGDDTAAVLEFADALTAGGHRHQIVALPG
SDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAE
LRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLI
ARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAG
YLASHGAGHVVLTSRREPGDDARRRLDGLREQYACDVRVITADVADAHDVARLMTTVAAE
LPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSS
IASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMADAESRARLEQRGV
RTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELPAAATGAA
APATVPGKPPLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRDEAGFFDLGMDSL
MAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTARTDD
PIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDIDEFYDPDPDTPGKTYTRFG
GFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGV
AANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQ
ACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGV
LVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADV
DYLEAHGTGTPLGDPIEVQAAAAAYGAGRDADRPLLMGSVKTNIGHTESASGAAGLIKVV
LSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHV
LVEEAPPQLHTADAAPVEPAATAEAGTDDSPQVLALSARSPEALVELARRYDDWLSATPG
LDIADVCHTAGVGRSHFEYRAALVVDSVERAREGLAALAEGRTPAGVVRGEHVHRPTTAW
LFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHT
SFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRM
FGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPNTVLSGPGEDLEEIVERFEDEG
IRCTWLATSHAFHSELLDPVLDEFEAYAAQFQFAAPTLPLVCNRTGAVLTGQTPLDAQYW
RRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVA
DRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFWPKASSIAVDGGTAAS
GILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAAVGTPARLKD
VFFYEPIILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSD
PDAAADEQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDI
LVGAELAEQLGSEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVTLAEKMP
RRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRL
LYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARG
AGFSGVVWRCATPGRKESGSASAESARLEAEITNLLSAVHAAQGPSVKLPGGLWIVTEHG
VACESGEPVDPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDLLAALLAAPGIQEPE
IAVRQGKLLASRLLPWARSGHLTLPRGGDFVLAPTERGAIDNLRLTETDVPEPDEGYVQV
RVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFAS
RFNVPAQFLAPIPDGIGAVEAATIPAAALTVRLAFDWAQLKPGDKVLIHAASGGVGLAAI
QMAQQSGAEVFATASTFKRSTLRRLGVKYVYDSRTTDFADQILADTNGAGVDVVLNSLTS
AGFVEATLKATAQGGRFAEIAKRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLL
TEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIGKIVLQVPKPLQPQQDRSYLIT
GGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVGDEA
QVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHLDRLTRDD
DLDFFIVSSSVSSLFGSPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASS
EAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPILDLV
LPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPAASSRFLDLGTD
SLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDAEAPETA
>A0A2P8AMF1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MH33|TrEMBL
MLGYASTATVGPDRSFTELGFDSLTAVDLRNRLTTRTGLSLPATLVFDHPTPAALTGHLL
AQLGPGPAAPTLLDELDRLEAAFAATPPETLAELAADEEIRSTVAARLRALLTRWDGDGG
VTATLDDASDDELFDFIDSRFGRS
>A0A2P8ANV9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MH33|TrEMBL
MPAGAAAEPADRIAALIDGAGGSVHTLVVDPATASRTDLAERLPAGGSTRVVSLLALDER
PHPDHPNVPAGLTGNLTLVQAVTDAAPAGPLWLLTRQAVSTGPGDPLAHPAQATTWGLGL
VAALEHPAHIGGLLDLPAELDPAAGEHLLRALTNTDGEDQLAVRPQGTHLRRLARAARAE
LPDTPAWQPPGTVLITGGTGAIGRYAATWLARHGTRRLILVSRRGPDAPGVADTVAELAD
LGAQAHVLACDLADRDAVAALVDGLRRDGETVRAVVHAAGVGRLNPVAVVTADELAEVVS
GKTAGARHLDELLDPDDLELVVYFSSIAAAWGVGDHGAYAAGNAFLDAWAQSRPAGRARV
VSVNWGPWAGGGMVSDEHAVAMSRRGVTLLDREPAMAALRAAIEGDGAVLTVADVDWARF
APVFAAARPRPLISDLPEVTALPSGPDPADEGGAEVLAGLRKRLADLTAAEQNRLLVELI
RTAAAEVIGHDGPYALEADRPFRDLGFDSLTAVELRGRLARLTGLDPASSVVFDYPTPQA
LAEHLRAQLVDEASVAALPTVEELDRLEDALALRERDDIGRVRITLRLHRLLERLGAEER
SAEVADVTDRLQLASNQELFDLVDRDLGLS
>A5GFJ7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Geotalea uraniireducens (strain Rf4)|TrEMBL
MKEQDVKTDLSTSEAPLAIIGIGCLFPKANDPDAYWSNITEGIDAISDIPPTHWQIADYY
DRDPKSPDMTYGQRGGFISPVPFNPMEFNIPPNIMEAIDTSQLLGLVAAGHALKDAGYGA
ERDYDRSRASVILGVTGTLELVIPLGARLGHPVWRQALKESGVDDTVAADVVQRISDSYV
PWQENSFPGLLGNVVAGRISKQYDLGGTNCVVDAACASSFSALHLASMELASGKADMVVT
GGIDTFNDIFMYMCFSKTPALSPTGNAKPFDAAADGTILGEGLGIVVIKRLADAERDGDK
IYAVIRGVGSSSDGKGDAIYAPNATGQKKALINAYNRAGVTPDSIGLLEAHGTGTKVGDA
VEVSALRDVYGEAETPWCSLGSVKSQIGHTKAAAGAAGLIKAALALHHKVLPPTIKVEKP
LEEVSAGRTPFYLASEKRPWLSRGTAPRRAGVSAFGFGGSNFHVVLEEYQPTKKAVDWDG
NVQLLAFSADDSGKLETALAGVPADIAWSELRNAAATSRAVFNGNAACRIALVVERERTN
LASLIANARAMLRKSPQSPWNTPDGAFFACGEKPGKLGMLFPGQGSQYAGMLRDLACRFP
QMLDTLAAADDGFASQDGTRLSDRIYPVSAFDVQTREKQEAALRATEAAQPAIGATSLGA
MKILKSFGVAPEAVAGHSYGELTALCASGRFDEAALHELSRLRGRLMGEGKGDKGSMLAV
STSLATVEQVIAEEKLDLVVANRNAPAQAVLSGSSAEIERAAAVFTSRNLPCKKLPVAAA
FHSPLVADAAAPFLSALANIELKGAQVPVYANTTAAAYPVDTALAKALLANQLAKPVEFV
AEIDAMHADGVRTFIEVGPGARLTGLVKAILGDREHVAVAVDASAGKRSGIADLARTLAQ
LTVLGYGVRLSAWDEGYQAPANTGRKPAMTVPICGANYVKPKPKRPPVAPVRPAAAVPHT
ATPVTPVAAPPGNPNQAATGYPAVPRPVSHEALAESLRITRESMAVLQKMQEETAQLHRR
FLEGQETAGRTFQTLLEQQQRLIQGGNGPIPFSAVAPAPAATIAAVPPIQPAIVPAGPAP
IVTTVSAALSAPAVPAAPAAPAATSGAGDRIARTLLAVVSEKTGYPVEMLEMEMGMDSDL
GIDSIKRVEILSAIQERLPGAPVIGPEHLGTLRTLGEIAAHLGAGMDTAATVAPVAASTK
ALAAPAGNIVAETLLAVVSEKTGYPVEMLEMEMGMDSDLGIDSIKRVEILSAIQERLSGA
PVIGPEHLGTLRTLGEIAAHLGAGMSPSTAVAPAIVVPAAVISAGKNVAETLLAVVSEKT
GYPVEMLEMEMGMDSDLGIDSIKRVEILSTIQERLPGAPVIGPEHLGTLRTLGEIAAHLG
AGMGTSAATPPATAIMAVAASSNDNVAETLLAVVSEKTGYPVEMLEMEMGMDSDLGIDSI
KRVEILSTIQERLPGAPVIGPEHLGTLRTLGEIAHYLAGAPATAEPKAEAAPAVTAQPAS
TSAPSAIGRSTIVPVLLNDSADSGQIALTSGGEFWVTDDGSTFTTELCTILHGRGLTVRR
ITGFESRDMVPSGKISGLVISAPVNGTTDLFLENAFLLLKTVAPALRQAGESGGAVCVTV
SRLDGAFGCGGDTTLSDPLSGGLAGLTKTAAREWPEVTCKAIDLGEFPAPTAMARAVAEE
LFRTGPVEVGLTPTGRITLELAELPAATAPVSAPIREGDVVIITGGGRGVTAATAVALSE
AYRPLLVLLGRSPEPAAEPAWLQSLGEEAQIKRAIIEQAGGKLHPRDIEERYRQVIAGRE
LRATLDRIAAAGGKAVYRSVDIRDAGEVRNLLVEIRREHGLVRGIVHGAGVLADRLIADK
SREQFARVYSTKVAGLRTLLAATRDDDLRFLALFSSTTGRFGRIGQVDYAVANEVLNKLA
QAETRRRPACRAVSINWGPWDGGMVTPALKKVFAGEGIGLIGLAAGGEFLVNEIAAAGAP
IEIVAIAGATGATVAASSPSRPQTLAEAFALTLTIDGYPFLRSHVLDGKAVLPMAVIAEW
LAHGALHGNPGFRFHGFNDLRICKGVVFEQDTPCTLHVLAGRAEKRDSSYLVPVELTSVG
KDGRSVLHARAGIVLATRLPEGIRSIIEIPSTPYEPRNGELYDRERLFHGPELHGIEHVD
GCSAKGIAAMVKGAPAPAVWIKQPLRSAWLTDPLVIDSAFQLMILWSFERFGAGSLPCFA
GRYRQFQESFPREGVQVVIRVTTEREHSATADMEFLDRHTGKLVARLEDYECVIDPSLKQ
AFQRNQLPQPGRVRLGVA
>A0A2K8RE99|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MRAAWRHGEELYADVALPEAVRASGPEADGPEFVLHPALFDAALHALALDGLVKDGSGAV
GPAVAGLSPPFAFGGVRVHTTGVQRLRVRVGPGPDGQAAVELADETGSPVATVRSLTLRP
LPRTGPATADPVTGALHRTDWVPLTESVRWRAPVAMARWGVLGTAGTRLVDTLAPPGSGV
PVYRGPAACDAPVAVVVAPCPPPDTTGGARDQAAGLLRPVSAVRHPGFEPGEALPATLDA
LVTAQAIAVRAAAAEGPLVLLGRSAGGWVAHAVAERLESEGAAPAAVVLVDTYPPGHRDR
GQALSAMTSDMLRRAAEFASAGPDRLTAMAGYFELFSGWKPAPLACPTLYVRARDTPPGA
EPAPDWSLPHAEVTVDGDHFTMLEEHARTTALAIHRWLGAGPV
>A0A2K8RE83|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MANEDEFLHYLKKAAADLRDARQQIQELEARDREPIAIVSMACRLPGGVDSPESLWDLVA
AGRDGVSAFPIDRGWDLEGIYDPDPDHPGTTYAREGGFLDDAAGFDPAFFGISPREALAM
DPQQRLLLETTWEVLERAGIDPAALRGSRTGVFTGVIHNDYADWSADDTDQLEGYLGNGS
AASVASGRVSYTFGFEGPAVSLDTACSSSLVALHLAIQALRSGECTLAITGGVTVLASVA
PFIEFSRQRGLADDGRCKAFAADANGFGMAEGIGLLLVERLSDAQRLGHPVLAVVRGTAV
NQDGASNGLTAPNGPSQQRVIRDALTNAQLSATDIDLIEAHGTGTALGDPIEAQALIATY
GQHRDQPVRLGSLKSNIGHAQAAAGVAGIIKTVMAMRHGIMPKTLHIDEPTPEVDWTTGT
VELLTESRDWPTTNQHPRRAAISSFGVSGTNAHVILEQAPTTPEPDTSEAPPAGPVPWIL
SAHTEPALRELARRLVSRDEGSVTDVAYSLLHGRAALPCRAVMIGATREDFAAELDALTC
ESGRASKVVFVFPGQGSQWIGMGRRLWESSAVFRDSVLRTDRALAEFVDWSAAAVLAGEP
GTPDLDRVDVVQPVLFTVMVALADVWRSYGVEPAAVVGHSQGEIAAAHVAGGLSLRDAAR
VVALRSKALTALAGEGGMVVVQRSVAYVEDLLRQWEGRLSVAVVNGPEAVVVSGQVAALE
ELLATEDRARRVAVDYASHSAQVERIEEELARTLTDVQPMTSRVPLFSTVERDWIDTASM
DTGYWYRNLRQTVWFDDAVGRLSEAGFDVFVEVSPHPVLTASVRESCPDAVVTGTLRRDH
HDVAALLAAARELHIGGARVDWAAVVGEGRRVDLPTYPFQRDRYWLERGSGSGGDAAGLG
LLPTRYPLLGAVTTIAGSGAVVLSGRLSVASMPWLADHAVADTVVLPGTALVDMAIRAGD
EVGCGVLDELVVQTPLVLDRAATVQVSVGPAEADGRRPVSVHARRDDGDWVEHAVGSLAE
EADVPVPPRSWPPAGAEAVDLTGLYERLADGGLAYGPAFQGLEALWRQDGSLYAEVALPE
AAGDTAGYAVHPALFDAALHAVVGTAELSGIRLPFAWTGVAVHATDATRLRVRLDTDDTG
AVRLLATDTTGEPVVTVDALVTRPVTADQLRRADSGPDGLYAVEWVSHTPATPATVPGFE
RYVVEPTGDDVVADTHRATTDTLAHVQRHLTATTTPLVVQAPYDDLAGAAVWGLLRTAQT
EHPGRIVLVDTDDHPASQEVLPILVASGEPQARIRDGAITLPRLARLSADTESVAIGDGT
ILITGGTGSLGSLVARHLATEHGARDLVLVSRQGPDADGATELTNELQQHGARIRVRSCD
TTDRAALAALVDDIGPLTGVVHTAGALADATVEHLDADALATTFAPKANTAWWLHELTQD
HPLTLFALFSSIAGILGSPGQANYAAANTFLDALATHRHGLGLPGTSLAWGSWQRVGGLT
RSLGATDRNRQARAGLRPLSDAEGTALFDAALAAGTGPVVAARLDLAALGRAEAVPELLR
DLVVRRGRRQAGNAGDASWADRVSAMAPQDRMNAVVELVRGQVASVLGHSDARRIAVDQA
FKELGFDSLTAVELRNQLTAATGLRLPATLIFDYPTTAAVAGLLAERLSGRTASAVPDPR
VAPVSATDSEPIAIVGMACRLPGGVTSPEELWELLSSGGDGISGFPTDRGWDLEHLYHPD
PDHPGTSYVREGGFLHDAGDFDAALFGISPREALTMDPQQRLLLETTWEVLERAGIDPTS
LRGSRTGVFAGVMYHDYISRLRHFPSELEGYTSNGGSGSVVSGRVSYTFGFEGPAVSVDT
ACSSSLVALHLAVQALRTGECTLAIAGGVTVMASPSSYIEFSRQRGLSPDGRCKSFAATA
DGAAWSEGATTLLVERLSDAQRLGHPVLAVVRGTAVNQDGASNGLTAPNGPSQQRVINTA
LADARLTAADVDVVEAHGTGTKLGDPIEAQAIIATYGQDREHPLWMGSLKSNIGHTQAAA
GAAGVMKAVLSMRHGVMPKSLHIDEPTPEVDWSAGAVELLAEARDWPATGRPRRAGVSSF
GASGTNAHVVLEQAPETESNDAAEDTPEQSAPSGPVPWVLSAQNEAALKDMARQLVTETE
GSVHEIAHSLITQRSTTLPHRAVLVGSTREEFATALEQITGHTPDGGKTVLVFPGQGSQW
VGMGQRLWETSALYRDTIHEVDTALSEYIDWSVTDILTGQPGAPTWDRVDVIQPVLFTTM
VALATLWQHHGLTPDAVIGHSQGEIAAAYTAGALTLQDAARITTLRSKALLPLTGHGTMI
SVLAPPQTIQDIADPDHWNTRIWIAAHNAPNTTTITGDTQAITQLTQQLSHHRIMRWQLP
GVDFAGHSGHIDQLHQQLQEILAPITPQKPTTPFYSTTDNTWITDTTLDADYWYRNLRQP
VLFQPAINHLSSNGYTTYIETSPHPTLTPSIQETNPNTTTIHTLRNEQDDTAAFLTALGH
AHTHGHPITWHTLIPAATTIPLPTYPFQHTRYWLNDKPTAGTQDATQLGLIPTPHPLVPA
TTTLAETGATILTGHINPAHHPWTADHAVNGTPLLPGTALVDIALHAGDHTNHTTLDELI
IHTPITLTHPTTIQLTINPPDDANTRTLTIHTSDNPDNPWTAHATGTLTQRQPTPDTPQT
TWPPTNAEPIDLTGTYQRLATTGLEYGPTFQGLRALWRRDSRLFADVRLPDTDHTDSTDS
YGIHPALLDAALHALVAVSDGDEIRLPFAWTGVTLHATGATKLRVELEWDASGSASLRAF
DPSGQPVVTVESLASRVISPEQLRSASARSGPLYRPEWIAWSGVGRSGGAVEFERYEVPT
VGDDVLADTHRITTETLTRIQQHLAADTTAPLVIEATHDDLAGAAVWGLIRTAQTEHPNR
IILIDTDNHPTSRKALPTLIASGEPQARIRDGAITLPRLTTVAPSEPVAIGEGTVLITGG
TGSLGSLIARHLVTEHGVRDLVLASRQGPAAPSATELSAELQQLGAQVRVRSCDTSDRAA
LARLIDETGPLTGVVHTAGALADATVDHLDADALATTFAPKADAAWWLHELTQDQNLTLF
MVFSSLAGVLGSAGQANYAAANSFLDALITHRRSHGLPGTSLAWGSWERTSGMTAHLTQA
DHDRMARAGLRPLTDEQGLEFFDGALAVDLGQVVTATFDLPAIGRSGAVPVLLRGLVRAP
RRTAVGADSGGAEPWTERVAALAPDARERSVLASVIEQVAQVLGHPDPGAIEPDQAFKSL
GFDSLTAVEFRNRLSAMTGLQLPATLVFDYPAAGAVTRYLLDQVSPAPAAAGPDDDPDER
ELRRVLERVPVARFREAGVLEALLKLAGPDPARTPDAAEPDEDIDAMDAEALIRHVMDGT
GA
>B8MS66|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MVEHRGINRLPALRREILLFGPLALSFDQEAFKHLRKTIIDSKENYWALDALNSLPYYYT
TIRAAIPGINGVNGAQLQDLKSALNNEKQLLTGFPLSNTLLIPLIVILHLTQYWRYLEQA
SMELESNIDLFVASHHNKETVGFCTGLLSAMAVSAAKNQREFCKYAAVAVRLGLLVGMVV
DAQDGSSAHGPSKSISASWKSSERREEAQRILNEFPQAYISVYYDEDRATITAPASKIPD
LHQRLRAAGIVTADVGLNGSFHTERYRGQLESIIQFCDSHPDFQLSDASKAIIPTRSNAT
GDFIREGALHQHALQSILVNPPQWYQTFTAVRDACAQEEGTVIVSFGSERCVPPSLLRGL
SQKVVTVADLDIFKKDQYTYSENDIAVVGMSCKVAGADNLEEFWDLLCMGKSQHREVPKE
RFGFETVFREVDPNRKWFGNFIDGHDQFDHKFFKKSPRESATMDPQQRHLLQITYQAVEQ
SGYFHSANPDRHIGCYIGVCACDYENNIACHAPNAFSATGNLQGFIAGKVSHFFGWTGPG
LTIDTACSSSAVAVHQACKAIITGECTAALAGGTHVMTNPLWFQNLAGASFLSTTGQCKP
FDIKADGYCRGEGIATVFLKKLSAALNDGDQILGVITATAVQQNQNCTPIFVPNVPSLSD
LFRNVVKQSRLQPADVTVVEAHGTGTAVGDPAEYDSIRSVLGGSYRENQLTLSSVKGLVG
HIECTSGIVSLIKVLLMLQKRMFPPQASFTTINPAIKATPADKMHIPTAVQTWDANFRAA
LINNYGASGSNASIVVTQPPAIAAKSINETPGLKYPFRFCGFDDQSLRRYFKVFRQFLGR
KSYSEKDLSLQNISFNLNRQSNRQLDRTLFFSVKTKEDLEQKLIAFENGDQSVTSLARSE
SRPVVLCFGGQVSTFIGLDHTVYERVAVFRKHLNTVDAVALSIGVKSIFPGIFKTTPIND
TVHLQVMLFACQYACARSWIDSGVQPVAVVGHSFGELTSLCVSQSLSLQDTVRMIVARAT
LIRDSWGSDKGAMLAVEADLAKVEKLLAESSAARQGLTPATIACFNGPRSFTLAGAVAAI
DAVVETISKPAFSSMKYKRLNVTNAFHCALLDPLLDRLEESARGLNFREPVIPVERATES
RTEEPFTAKFVADHIRSPVFFNHAIQRLAQKYSSCIFLEAGSNSTVTNMANRALGNPSSS
HFQAINVTNQNGWNNLVDSTLSLWKVGLSVHFWAHQSSQTKEHSLLLLPPYQFEPSRHWT
ELKSVPTLTAAPALGVVEKEDVKLPDTLLTFVGYQDSGKRQAKFRVNTMIPKYEKLIQGH
IIAQTAPICPATVQLDLAIESIRIIRPDLSASGLEPQIQAVENSAPICVNSLRAVWLEVT
ADDFDQGTSWQFQVYSDDLENGFSKTIHTTGQIIFRSVDDVSLKYEFARFERHFRHQDCV
DLMRGGDVDEVLQNRNIYKMFAEIVDYGEDYRGLQKLVSKENLSAGYVVKRYNPETWLDG
HLADSFCQVGGIYVNCMTERASTDMFIANGIEQWIRSPKVRQQDARPESYHVLAIHHRSS
DKAFLTDVFAFDSTTGALIEVILGISYVRIPKASMSKLLSRLTVKSNLKEPAEMPLLPEP
ASVNLFDTPKNVSIHPQSDSLPRQSVPHLKPLKMKKEKGAQSDKAQLTQKLKAILAELSG
LEVAEIKDDSELADLGIDSLMGMEMAHEIEKAFTITLPESDLMEVVDMPSLIKCVQKAVG
GGAVPVEDTTEQSAYESADSDDKSTDYTMPSTPEEELCGVDKSMHEFLGKQNVELNLPFA
TVMEAFNETKSLTDDRIKEYQQTYYVKSVLPMQSEMCVSLVLEAFDQLNVRIRSARAGDK
FTHITHPKEHTRLVDYLYKMLEDANLINIDGDVITRTAIQAPRPSKEILDELVSRYPDQN
AADKLTFYTGSHLAEVLRGETDGIKLIFGTQDGRELVSNLYGDWPINRLFYRQMEDFLER
LISKLDMSQGPIKILEMGAGTGGTTKWLVPLLAKLNAPVEYTFTDLAPSFVAAARKKYSK
QYPFMKFRLHDIEKAPADDLIGTQHIIVASNAVHATHSLSESGKNIRKALRPDGFLMMLE
MTGKLYWVDIIFGLFEGWWYFDDGRTHAVTHESQWEKSLQAVGYGHVDWTDGVRPENKLE
KLIIAFASGTRYERLHIPRPIESTSADCAARQAVVDRYAKEMTSDFGIVTGESPYMNSQR
RQESKGYSVLVTGATGSLGCHLVAVLTSIPDITSVVCVNRRSRQQPLERQHRSLLQKEIF
LSEAAAAKLRVIETDMSKPELGLPKNEYDDLLNSVTHIVHNAWLMNAKWPLKKFEPQLQI
MRNLLELAYGISLRRSSDRISFQFISSIATVGHRPIWTGNSSVPEEPMTIDSVLPTGYGE
AKYICERMIDETLHKYPERFRAMVVRPGQVAGSSTSGYWNTMEHLSFLVKSSQTLCALPE
FDGVLSWTPVDAVASTLVDLLLLPKDQSPFPFYHIDNPVRQLWKEMIPILADALDIPRTN
IIPFQEWIQRVKDYPRQAEGPEGDNPAILLVDFLDKNFIRMSCGGLLLETKKSRAHSQTL
ANLGPVSAEIVELFIKSWKRMGFLRS
>A0A0J6C4P8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Bordetella pseudohinzii|TrEMBL
MAKRVAIIGLAFRFPGTSTEQYWSDLLDGKDLITQVDPGRWSTDAYLHPDKEQPGTAYTH
AAGSLGDISGFDADFFGISPREATLMDPQQRLLLEMSWEAMEDAGIRPSQLRGSDCGVYI
GISSADYAYRMSEDLNVVDASTATGNTSSIAANRLSYFFDLRGPSIALDTACSSSLVAFH
QACRAIQSGECSHALAGGISLHLHPYGFITFSKASMLSREGRCNVFDASGDGYVRSEGGG
VFVLKDYERAVADGDRILAVVAGSAVNTDGRKSGLTVPNADAQIELMRGAYQQAGIAPAD
LDYLEAHGTGTAVGDPIETRAIGAALGKRRPATQPLPIGSVKSNLGHLEPASGVAGLVKA
IYSLTHRTVPATIGVRQLNPNIDFKDWNIEVVTQNRPLKPKGKLTIGVNSFGFGGSNAHV
ILESPPAVAETAATKLVKNAPVPLVVSGKTQDALRAAAAAMAQRLRADAGRPLYDIAYHA
AQRRDWHEERALVFASDKQRAAADLQSLADGGASKYRVSTGSAVKDAKGPVFVYSGNGSQ
WAGMGQRLMTDPVFAAAVHEVDALFSEYSDFSPAAELSNSDGNDRYDRTEIAQPTLFALQ
VGITRMLAQRGVVPVATMGHSVGEVAAVWACGALSLPEAVKVIYHRSRLQGLTKGKGKMT
AVGINADETEALIAELKLDQGLALAGANSHRGATVAGDPAMLDTLEAVLAERSIFHRRLN
LDYAFHSQAMDGIEHGIRQSLGDISPRDANLPFYSTVSGQRESGRKLDAGYWWRNVRLPV
RFETASAQAIADGFNVFVEIGPHPVLRGYLKDALGTADMAGSIFITASRGGDDPEKIHDV
AGQVILSGASVDWQALFPWKGEHITLPAYPWQREKYWHDTSSESPGLLMRQRVHPLLGYA
LAQHDGVWENRIDAQQFPALADHVVGDATVFPGTGFAELALAAARQWLPGEFADIEELEI
RAPLILSGTKRVRVILDKHDGRLRIEGRDQNSPDPWTLHATARILQETGSVPLRGDAVLS
LPARDPDFVEADHHQLTRLVGLQYGPAFRAISHGWLESAGSVLAVFQPEQTQDGSLDDTL
LHPALLDCGFQLIIQLLKDDGAIGQGMAFVPAKIGRLTLQAAQGQAKFVRARLRRRSPHS
LTADFDLFNAEGKRIASVQEARFRSIRLRKAAGEHLDFVDCVLTPRPHPLAPLPASPIPA
DTLARELRRLAQPPQEANNDRYTQEVDPLLESLCDRQAVEALRNQASGGHTLSAAMVERR
QRRHPAAAALFEHMLNRAIAAGAAQPSPTGWTLAPDEEGQPDAADIWNSLLREYPDYFPA
IYAAGRVGLHLPQLLRGAIDIEQVLPQIASPTAISRLVLGAERGQRLAGVVAQALRRARC
EPGQRLSMLEIAQDAPIFGPACCAVLDFNIADYRFASPDSQTVEDVRHTHLDSYPDASAE
LIGEDGLPGDEQRYDLVVLHCEFDTLEAARQALGYARACLKPDGKLLLRGMHPAQWMDFV
FGGRASWWHADGTPLPQAGYWMQCLQELGLACEPLIEFSPGSQSGPYLIVASAAQAQPQA
PAGEIRKQLLLAGSTGAGAALAQTLDEQLRAAGQQSTLVKGVDPARVEALIKEARLQHGQ
LHDIVLLDGWSEDEPAKDGAFDRQVRRCALAAAVIQACEHTDTSATVWIVTRNAGVSMGG
GDAQSAAIADAALWGYGRTLANEASNYRVRLVDLPGGPKTVPALLREILHPDAEDEVLIG
ADGERYAPRLRQVDRPAPTAEVREATQACRLGFDFPGQLRNLRWESYDAPEPADDQIEVR
IHATGLNFRDVMYALGLLSDEAIEQGFAGPTLGLEFAGEVTRVGSSVTEYRRGDQVVGFG
PASFGDRVLTRASAIAPIPNGISFEAASTIPSTFFTVYYALHHLARLEEGEKILIHGAAG
GVGIAAIQYAQWVGADIYATAGSEEKRDFLRMMGVTKVYDSRSLSYADEILADTGGIGMD
VVLNSLAGEAINRNLQVLRPFGRFLELGKRDFYENTRIGLRPFRNNISYFGIDADQLMSE
RPDLTRRLFGEMMQLFAEGALHPLPYTVFDANEVVDAFRYMQQARQIGKIVVTYRNGLRH
PHQARTAEARHLALPGDASYLVTGGLGGFGLRTAQWLAEKGARNLVLISRGGPASEEARA
GIAALTASGVRVHAAACDVTDAQAMEQLLADVARDMPPLRGIVHAAVVIEDGLARNASAQ
QIASTMAAKVKGAYHLHALTRGLPLDFCVYYSSATTLFGNPGQSNYVAANMWLEALAAHR
RAQGLPATCVRWGAIDDVGFLARNEKVKDALQSRMGGSATPSAVALDALESLLLTQSSGL
GVLELDWKSLARFLPSSDAPKFSALARQGADGASDDDQGLDIAYLLATQDDTALQHIFGD
MLKTEIGEILRVSADKIDPERSIYDMGLDSLMGVELIVALENRFGIRLPVMALSESPTVN
KLAARLIELLRGDQQSNPQDALSSTIGKLVSDHAAELSESTITEFVDEIKNGDAATPKRM
IP
>A0A1D2IK37|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. AVP053U2|TrEMBL
MAHEDKLRHLLKRVSAELDDTQRRVRELEESEREPIAIVGMSCRLPGGVDSPEEFWSLLE
AGTDAVSEFPRDRGWDVENLYDPDPDAPGRSYVREGGFLDGAGRFDAAFFGISPREALAM
DPQQRLLLECSWEAIERSRIDPKSLHGSRTGVFAGSNWQDYNTLLLNAEERSQSYLATGA
SGSVLSGRVSYTLGLEGPAITVNTACSSSLVAIHLAARALRAGECDLALAGAVTVMSTPQ
LPVAFSRQRGLALDGRSKAFAASADGMGFGEGVGVLVLERLSVARRHGHRVLAVVRGSAV
NQDGASNGLTAPNGPSQQRVIRAALASARLAPEDVDAVEAHGTGTRLGDPIEAQALLAAY
GQGRDAGRPLWLGSVKSNIGHAQAAAGVAGVIKMVLALRKGVLPRTLHVDEPSGEVDWDS
GAVRLLTEEREWPSEEGRPRRAGVSSFGISGTNAHVIIEEAPEVEPWPEAPSVDVVPWVL
SARSAEALREQAVQLASAVGGLSPVDVGWSLAATRAVFEYRAVVVGREREELLAGLSAVA
AGRPAVNVVTGSVSSGRPAFVFTGQGSQRLGMGGGLCERFPVFAGVFDEVCGRVDPGLRD
VVFGSDAGELSRTVWAQAGLFALEVALFRLLESWGVRPGYLIGHSIGELSAACVAGLWSL
EDACRVVAARGRLMQALPSGGAMAAVRATAGDLAGFLGDDVVIASVNAPGQVVISGPEGG
VERVLAACGARSRRLAVSHAFHSPLVEPMLGEFRRVLESVEYRAPSLPVVSDVTGEWVDP
EEWGTPEYWVRQVREPVRFADGVTTLLDAGVSSFVELGPAGTLTSMVTHCAESADVSVTA
VPTLRPGHDDVRTVLTAAATLYVQGHPVDWAPLFPRARTVDLPTYPFQHQHYWLERAARP
TVEDAPREPLDGWTHRIGWVPLVDEEPAPVLAGTWLLIRPEEGPRPLSDAVADALSRHGA
TVVEAARVPHDADTELTGVVSLLGSGADSDGGLDATLRLVQDLAAAGSAAPLWIITSGAV
AVGTSDTVPNPEQATLWGLARAAAAERPELGAARIDLPADLTEQAGRRLCTRLLDRREQE
TAVRQAGVFARRLVRARTGDRRWTPRGTVLVTGGTGALAGHVARWLAEEGAEHIVLAGRR
GPNGDGAEALRADLVAAGVKATVVRCDVADRDAVRMLLDAHRPSAVVHTAGVIDDGLLTS
LAPDQVERVLRPKLLGARNLHELTRDRELDAFVLFSSLAGVLGGAGQANYAAANAYLDAL
AAHRTAQGLPAASLAWGPWEGDGMAAAQEVADRLRRSGLTPLPPEQAVRALGRGHGPLVV
ADADWARLADGSTQRLLDELPEVRAVRPTAPAVEQRPDLPARLAGRPAEEQSAVLLEAVR
EEIAAVLRYANPARIGADQEFLALGFDSLTSIELRNRLATRTGLTLPATLTLEQRTPAGL
AAHLRERIADRSVGSGAAPALGSAAVPEAGGGSGLGELWQEADRHGRRLEFIDVLTAAAA
FRPAYRDPAELQLPPLRLTAGGDEPPLFCLPSHLGKADPHKFLRFAAALRGRRDVFVLRQ
PGFVPGQPLPAGLDTLLDTHARAMAGHDRPVLLGYSAGGLAAQALAARLAELGRPPAAVV
LVDTYAPDETEVMARIQGAMEQGQRDRDGRTGAAFGEAWLTAMGHYFGFDWTPCPVDVPV
LHVRAGDPMTGMPVEGRWQARWKLPHTAVDVPGDHFTMMEDHAPRTADTVHDWLGTAVRR
PERTRN
>A0A2X3MVD8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. Ea1.12|TrEMBL
MRPVRLVRRARNQPNLRSERVIVSESGPPRRLADTPIAIVGMAGLFPHAHDFREFWQNIV
DARDCIEDIPASRWNIDDYYDADPTVPDRTYSRRGGFVPDVAFDPLEFGLPPNQLEVTST
LQTLSLVVARDLLRDAGARSAHSADGADWYDADSTGVVLGVTGPVPLMHPLAARLTTPVL
REVVRACGLTEDDAQAIATRYAEAFAPWEENSFPGLLANVTAGRIANRLGLGGMNSTVDA
ACAASLSAVRMAIAELVDGRADMMIAGGADTENSIFGYMCFSKTQALSKSDRIRPFDEGA
DGTLIGEGIGMLALRRLADAERDGNRIYAVIRGIGSASDGRSKSIYAPRAEGQERALRRA
YADADCSPASVELFEAHATGTAVGDRTELTALDAILREAAGDEARFAAIGSVKSQIGHTK
GAAGTASLMKLALSLYQKTLPPTINVERPSGPLADDNTPLYVNTHTRPWVRDPRRPVRRA
AASAMGFGGTNFHVVLEEHRAERPATGLLHRTARAWLWHAPDPAALRAALAAGEPPADGL
ISTDGLIPADHARVGFVTPAANPDGGAADGADLRRIALEQLAAAPDAEQWTHPAGVYYRR
RALPDPRVGALFAGQGSQYLEMGLDAALGVPTVAQALDDANAVFADDDARLAAVMYPPPV
LDPQVRQEQESRLRATRYAQPAIGALSAGQFRYLRELGLDCAGYLGHSFGELTALWAAGA
LDDTEFFRLARARGAAMAPPDPATGGNAGDGNAAGGDPGTMAAVQASREQITEILTDFPD
VVVCNNNAPDQVVVGGGTQAVEAVVEELARRGMTGRLLPVSAAFHTRYVAHAVERFAQDL
AQARIGAPAAPVYANTAGAAYGPDADSNRVVLAGQLLAPVDFVAGVTAMRAAGCNIFVEF
GPKQVLAQLTRRILDDAPVTVVSTDGGPLRDGDVVLKQAAVQLAVLGLPLADINRHDATA
GAEGDTEQPRRAAMTVTLTGAEYVPQSRRALYQAGLTDGFQVSAVAAAMNGGPAAVATPP
AAPAEPVPAPQPALTSAPQPALPAAAPAAAELPAVPAVAGSPAAAGRPAGSAPVPAAAAL
GAGPAGAEVSEAVALHLDLHGRYLDGQLRVTEELVGLLRDGAQNGDQAGWVPAAVEQVRD
QSLAAGRAHVHANEVLAALAGLELAAGGHAPAAPAAGAPARVGLAPRSTSAAGPAALAPP
PAAPAVPAPVIADAPATVPADSAGPVAVPAQPTGNGHHPHQPGTLIPAAAPLPADVWRVS
ESMDSLTRHTSSEGAEARPAAGPDEAGVRTALLGVVADRTGYPAEMIDTGMDLEADLGVD
SIKRVQILGALQEHFPTLPSAGPETLAEMRTLNHITDYVLTSLGPVNPAPDGAPNGTSPK
GDQPKGGEPTGTAGLNGHHAAGHGDDAVLPHRPVELVPAAPVDILDATPFGADPVAVLID
ATGHDAPAPELTALADGLTARGFAVRTVRLPGHGGTAGDGADQADPLDGWDAAEVEQALA
GALGGDGAVDLCALLIAADGGDGAWAAGIRRLADTVLVAKHAAGPLSRAAARGGRAAFCA
VTRLDGGLGLRGDVPAVERLVGGAAGVVKTLLREEPALFCRALDLHPAHVPAAVAELVLT
ELWDAATDLAEVGLDATGARWTVRPGPFGDRAAQAEDREAGTGAALPVLGPDDIIVVTGG
ARGVTADCVRALAARTRPRFVLLGRTAADSDPEWATGVADGGLLAAAAAALAAQAGPGGP
RPTPRQAEAARRDVLARREIRDTLAALTAAGSDGEYLAVDIADRDAVRAALEPYRGRAAA
LVHGAGALADSALTAKTPDAVRRVLTPKLTGLRNVLDALGDGPGSPLRHLVLFASVAGLM
GNPGQADYAAANEALGRLAAGWKHADRGRHVTAIDWGAWDGGMVDADLRELFRSRGVALI
DRTAGAEAFAEQFEPARVDDVCVLVGSAEALTGGSDVRPAPALVARRELREIAEHPVIRD
HQVGGFPVLPATFGLGWLVNVVERAHPGLTVVEVRGFDVHKGVVFDGTGELAFQAHTAAA
EREGAGTGGRVVVKASVRSPGALPAGLSRYAATLVLAAAPPAPAEVEDWPRLEAEWTAPG
PEDGLEIYTGATLFHGPLLQGIRRIVARGDDRLVVECRLDGAEVGRGAFAGALHDPVLAD
LLLHGPSVLGRWLTGQACLPLAVGRIDYRAPLPAGEPFAVVIDGAAVRDTGVTSRVTAVG
RDGRILVRLHDVAMVGTPDMAAKFAEGTASWHKKEVSA
>B2IYP6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MSQMESIDQLSPSQRALLALKELRAKIDAMERAKTEPIAIVGMACRFPGGADDPETFWQI
LRDGTDAIVEVPSDRWDIDTYYDPNPDSPGKMSSRYGGFLKQVDRFDAEFFGISPREAIS
IDPQQRLLLEVSWEALENACQPPSELMGSSTGVFVGVTTNDYTRFYAQAGEQGIDAYQGT
GSAFSAMVGRLSFVLGFQGPCVALDTACSSSLVSVHLACQSLRNGECELALAGGVNLILT
PEANIMFSKARMMAADGRCKTFDAAANGYVRGEGCGIVVLKRLSQAQAQGDRILAVIRGS
AVNQDGRSSGLTVPNGIAQENLIRQAIANAKVQPQQVSYVEAHGTGTSLGDPIEVEAITA
TLGKEHTTDRPLAIGSVKTNIGHLESAAGVAGLMKVVLALQHQQIPPHLHLNQPNPLIPW
SELPLTIPTTLTPWQTNGETRIAGVSSFGFSGTNAHAILEEAPLEEAGRAGEQGSRGAGG
QGGRGEEIRKRPLHLLTLSAKHPQALQQLAQNYIKYFSSHPDITLGDITHTSQIGRTHFS
HRLAIIAPDHQQMQQQLQTYVDNSEIIGIHHGHSSQQTKKIAFLFTGQGSQYRNMGRQLY
ETQPSFRQTLDQCDTLLQPLLGESILSVIFSDNSESDRLNHTAYTQVALFVIEYGLAQLW
LSWDIRPTAVVGHSVGEYVAACIAGIFCLEDALKLIVQRASLMQALPQGGGMAAVFATVE
QVRPLIADYLQQLSIAAINGEQSIVLSGELEILNSVLQKLESQGIETRKLQVSHAFHSPL
MQPMLAKFEQVTATVKYQQPKLDIVSNVTGKIVRQQEMSNAAYWVEHIRASVQFAASMLA
LYQAGYEVFVEVGSHPTLLGMARRECPEVLEEKGLWLASLRKSRGDWQQLLDSVAQLYVA
GVEIDWRGFEADYLRHKVVLPNYPWQRQRYWLPTATTKPTVRQISENLLHPLLGYQLRSP
SLKDIVFETHLNTASLPFLDDHQIYDTVVVPGASHISMLLLAGQEILGTGAISLNNITFR
EALTVGDRQTINVQLILQPEAAGKYKFELFSFNKQIDNWLVHATGRVSQDVGDIEKPVSW
AELQTRCSQILAGSDFYAQVREQGLQLGQRFQWVESMWRCDGEALCQMQFPQEFADEINT
YLLYPGLIDSCFQFLGFALPQERRDNQVYVPFSINHFYFCESPDFNSRLWCYGKLNSQTS
STAGMFIGDIWLLNEAGELVAYIEGLCLKQAPRQALLRANQAPTQEWLYQIQWQPKSRLS
EQLPAISGRWLIFTDANGIGRVLAQKLEYQGKVCILVSIGEIYQQIAESQFQIDPSQPQH
FHQLLQDVGSENTPLHGIIHLWSLLETEQTNYLTSCGSTIYLLQALSKLSNCQARLWLFT
QGSQPVGDELTMNSLTQAPLWGLGRVIAIEYPANWGGLVDIDTNNSPEQTAELVLGDILQ
PESEDHLAFRNHERYVARLVRAKPQVSTQPVRFSADATYLITGGLGALGLEVARWMIKQG
VQNLVLVGRRPPSVTALNAIQEMEQAGVQVQVIQADITDFNQVKQLLSPCKSQLRGIIHA
AGVLSDRIILQQTWESFTQVMAPKIQGAWNLHHLTQDISLDFFVMFSSAASLLGVAAQGN
YAAANAFLDAFAYYRHSQGLPALSINWGAWAEVGMAATLDRSLSVGVERIGIEQGLQVLE
SLLSRADMPQVGVIPVNWQTFLKQYRAGKVPPLLQDFAEYTQPEEKSETTQSTILEKLQQ
VSDDKRQSLLLTHVRKLAAKVLRLNSWQNLDADKPLIEMGLDSLMALELRNVLENSLACS
LPATLLFDYPSLQTLVNHLIQDVMSLSKLEDSSSAPSPEESEPLISLEDLTRMSEAETEL
LLLKKLELIDGN
>B2IYN9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MGCRFPGGVNNLETYWQLLSQGIDASREIPSDRWSVDSFYTPHPDTPGKMYTRRGSFIDQ
VDGFDADFFGIAPREAVSIDPQQRLLLEVAWEALENAGQSTEKLEGSATGVFIGISTNDY
ARFHINSGDPNRIDAYSFIGCTPSVVSGRLSYVFGLQGPSLTIDTACSSSLTAIHLACES
LRKCECNLALAGGVNLMLAPETTIYFCQVKALAADGRCKTFDAAADGYGRGEGCGVVVLK
RLPDALADGDRIFGLIRGSAVNQDGRSNGMTAPNGSAQQAVIRQALAAAAVQPQEIGYVE
AHGTGTVLGDPIEIRALASVLCADRSQDNALIVGSVKTNIGHLEAAAGIAGIMKVVLALQ
HRQIPPHLHFKQANPHIDWQELPLVIPTQLTPWISDRLLAGVSSFGMSGTNAHVVLEAAP
VEEDKGTRGQGDKRNDESDRVYLLPLSARSPEALKEIAKAYRELLSGSLKLEDICYTASL
RRVHYEYRLGLVGNSAEELANQLQDFLEDIPNSDVNWGYQGSSRRQQIAFVFSGQGSQWL
GMGQELLTQEPVFREALEECDRIIQSHTYWSLIAELSAPPEKSRLDETEIAQPAILSLQV
ALVALWRAWGVEPSAVVGHSVGEITAAYVAGVLTLADALWIVIQRAKLMQQATGHGKMAM
LHLPEKAVAELIAPYEDKIAIAAINSPFSTVISGAIEAIEIILEKVEQQGVFCRRLPVNY
AFHCPQMDGYSRELERILEDIQPKSPYLQIFSTVSGQPEDSPLPLCASAPLPLFDAAYWG
RNMRQSVRFAEAMDSLIQAGYNLFVEVAPHSVLAKDMLECLSQTQQQGTVLPTMRRGDST
VSLRSLAKLYTLGHKVNWDNFYPNGGKFVQLPTYPWQRKRYWIEPIQPNVISTTASELSD
WLYEIQWQPQALLIKQQTIAPTHWLIFSDRSGIGETLERILQAQGHTTTVLYCTDASCTD
AIHRVSKVSNLQIVHLWSLDNTEQLVNCGGVLDLLQALAQVELPAVKLWLVTQGAQPVGE
ISKELAIAAAPLWGISRVIAMECAEIWGGIIDIDPASTLEEAANLLAAELSQSKSQENQL
AFRQQQRYVARLTRTVAIVSTSPLSLRTDSTYLITGGLGALGLRVAHWLVERGARHLLLL
SRRPPGEQAQAAIQEMEQEGAHIQVALADVTNQAELSTILHNLNYPLRGIIHAAGVLDDG
ILLRQTWERFAKVLAPKIDGAWNLHLLSRDCALDFFVMFSSVASLIGSPGQGNYAAANMY
LDILAHYRRHQGLPALSINWGPWSDVGMAADLNHRNLWSTENGVSYITPEQGLRALEELL
KQGKTQAGVVPIAWDKFSTAVQLPLLQQLTTKVSQSPSQPFLLRQLESTPVSDRRELLMS
AVQDQVVRVLRLDNSRPIDPERPLQEMGMDSLMAVELRNTLGKLVDKTLPAALIFDYPSI
SNLTEYLGKELGIFATTALPPTVESRELSPTEAIAVVGMSCRFPGADDLESFWQLLCNGT
DAIREVPGDRWDVDEFYDPDLSFPGTMNTRWGGFINNIDHFDPQFFGISASEARSMDPQQ
RLLLEVSWEALEHAGYSSEHLAGSQTGVFTGISTWDYFTLQLDPPPRGGTGMALSIAANR
LSYLLDLRGPSMAVDTACSSSLVAVDLACQSLRNGKCDLALAGGVNIILSPLTTVACSQA
GMMAADGHCKTFDQRADGYVRGEGCGVVVLKRLSDALRDDDHILALVRGSAVNQDGRSNG
LTAPNGLAQQAVIRQALQNAAVTPDGISYVEAHGTGTALGDAIEVESLWTVLKEGRTDNQ
PCRISSVKTNIGHLEAAAGIAGFIKLVLLLHREQIPPHLNLQTINPVLNLEQTQLQIPTS
LQLWKRGEQPRLAGISSFGFGGTNVHAIVEEAPLEKAGGAEEQRSRGEEIIIERPLHLLT
LSAKSESALQNLIGRYHHYLQENTGDRLADICYTANMGRSHFAHRLAFVVNSQAQLRDTL
AAFNVREKSPDVLYGKLDTQRQPKVAFIFAGEGSQYVGMGKQLYKTQPQFRSILEDCDRL
LQHHLQQSLLAILEDESLLTQPRYASPAVFALGYALAQLWRSWGVQPSVVMGGGVGEYIA
ACVAGVFSLEDGLRLITQQESWAEFEPIAKQVKFQVPQIPMVSTFYGQLLAADYIPDIDY
WRRCWQAPALFKGAMLALTQKGCNLFLEIGSDPQLSEIQQQGTWLQSIDDWTVLLHSMIA
FYINGVAIDWQKFEQGYQRCRVVLPTYPFERKRYWLDPAVIRSFSKKEENLCNE
>K9XDB1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Gloeocapsa sp. PCC 7428|TrEMBL
MFACNITVALSQLHNEIRNCETALMKLIQKKKSMADKVLEQDPINTQLQKNPIAIIGIAS
LFPQSRNTQQYWQKIIEKVDCITDVPPSRWDVDAYYDPDPKAPDKTYCKRGGFIPDIDFN
PMEFGLPPNILEVTDVSQLLGLVVAKEAMEDAGYDETRQFNRDRTGVILGVALARQLAMP
LGARLQYPIWEKALKSSGLSDADTQKIIDKIKSAYVNWEENAFPGMLANVVSGRIANRLD
FGGTNCVVDAACASSLGALRMAMSELVEHRCDMMLTGGVDTDNSIVAYMCFSKTPAVSPS
QNVKPFDAESDGMMLGEGIGMIVLKRLSDAERDGDKIYAVIKGIGTSSDGKYKSIYAPRP
EGQISALRRAYEDAGCAPESVGLIEAHGTGTMAGDPTEFTALKAFFEETNVGKQKIALGS
VKSQIGHTKAAAGAASLIKTALALHHKVLPPTINVTKPNPKLKIEDSPFYLNTETRPWLS
SETPRRAGVSSFGFGGTNYHVVLEEYTKEHNNYPYRIHQTPQIVLLSAATPEQLQHKCAD
LLAQLQGEAAEQHFAQVVGASQTLEVPVTEARLGFVADCASQAIALLQISIEQLKNNSTD
WEHPQGIYYRQSGIDPTGKVVALFSGQGSQYLDMGRELAINFPCLRQVYSQMDNLLTQDG
LQPISEIVFPPPVFDNAQRQKQQEALQQTQYAQPAIGVFSVGLYKIFQQAGFKPDFVAGH
SFGELTALWAAEVLSDRDYLSLVKARGQAMATPKQPHFDAGAMLAVKGDVSQVTTFIKQF
PLVTIANFNSTKQVVLAGTKLEIAQVQQALNAQGFSTVVLPVAAAFHTPLVGYAQKPFAQ
AIEATRFAAPKTAIYSNVTGKPYPEAPQAIQKILKEHLLNSVLFKDQIENIYASGGYFFV
EFGPRNILTNLVKETLGDRPHLAVAVNAHKQQNSDRTLRSAVLQLRVAGLSLKNIDPYQL
ETKTPTPKGNKSLNVRLNSANYISEKTQAAFAQALADTHISVAPPVPSTPVTNGHHPQPV
PAFSQPEAATTVTPPPTTVDYQKMLDSIESTLAQFNDHHGDILQVHEESLKHQSEYAQTF
FQLTQQQNVLLADAQDAAVRDSLERSMMRFHDHQAETLRIHEQYLQQQMEHSHSFFQLIE
QKYESAIAQGVTKAFQPKPSISNGNGNGHHANGHGVSFVEQSSKPAENIAVKPSPSEAPS
EPLLPITPPVTEPSISAPTALIDVADLSQTLLNVVSDKTGYPVEMLELEMDMEADLGIDS
IKRVEILGALLELYPGLPQPNPEELGELRTLGQIAEYMSRIATTLPVKAEVTTVDAVVQD
EVTTPVVSIPNPPIEPSISAPTALIDVADLSQTLLNVVSDKTGYPVEMLELEMDMEADLG
IDSIKRVEILGTLLELYPGLPQPNPEELSELRTLGQIAEYMSRIAGNLTATETLPKKQDS
GQPEISHNIMRSVVKLKVLPPPDRLECHLPQQHVCLITDNGSALTSQLAQALIAKGEKVV
VLSFPKSVIPQSAGVEKHIPRVVLEDLSETHLQQQLNAIAQHGSIGSFIHLHPTIHNERE
EIAYLNSETALLKHIFLIAKYLKEPLNSSATQGRSCFITVTHLDGELGIGQKNHYSAIAG
GLFGLTKTLNQEWETVFCRAIDFSTNIDAQQAVQHILAEIQDPNRLISEVGYGAKGRVTL
VRD
>K9XLC2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Gloeocapsa sp. PCC 7428|TrEMBL
MNQRSPQHDYRTLMQNALRELQQMRAKLATLEQNKTEPIAIIGIGCRFPGGADTPAAFWQ
LLQNGVDAIAEVPPNRWHLDSYFDPNPEAPGKIYTRYGGFIDNLETFDTEFFGIAPREAL
SLDPQQRLLLEVSWEALENAGIVPKNLSGSKTGVFVGISSNDYSHHLLTREPDEIDAYLA
TGNSHSTAAGRLSYTYGFVGPSFAVDTACSSSLVAVHLACQSLRNQECDLAVVGGVNRLF
APEFTINFAKARMLAADGRCKTFDAAADGFVRAEGCGVVILKRLADAIADRDKILALIPA
SAVNQDGRSSGLTVPNGPAQQSVIVEALRNGNIDPVQISYIEAHGTGTALGDPIEVNALG
AIFGKSHTFDQPLRIGSVKTNIGHLEAAAGVAGLIKVILALQNRQIPPHLHYKQPNPHIP
WQQLPIQVTTALTPWTGSIAGVSSFGFSGTNAHVIVAEATNSAVEASSHVDTPQILTLSA
KTLPALSELTKRYEAYLAANPNVSIADVCFNAQTRRSHFQHRLAIVAQSSREAQEKLKLF
NTHQQESTTKHRPKIAFLLTGQGSQYANMGKHLYQTQPIFTQHIDRCCELLQPYLSIDLR
EVLYPKAECQLNLNDTIFAQPAIFIVEYALYQLWTSWGVYPDVVIGHSIGEYVAATIAEV
FSLEDALKLVVTRAQLMQALPPNGKMVAVAANETTVAAIIEDYQQVSIAAINAPENTVIS
GNINAVDAIVTTLEAQHIAAKTLAVSHAFHSPLMQPMVQKFAQIAREVEYNAPKLNLISN
LTGKLAGDEIATPEYWCEHILQPVRFAAGMKVLAELDCNICVEVGAKPTLLGLGRAILAN
SNILWLPSLKPSDQINPILSSVAQLYVAGVKIDWRSFGCDRPLLALPNYPFQRQRFWVDV
AKKSPRIIDNGLHPLLGQRFELARPKTVYFENYLGLNRLSYLQDHQVFDKIIFPGAGYLE
MAIAAGNLVLNTNVILENVEISQALVLTETKLQLVLQHNKFEILSLSAATDEWIVHATGK
IQSLNEPQNPTFIDIATVQRQCQEINPLLYYQTLRSHGINYGATFQAIAQLWQGENQALA
QIQLPPELTDTNYRLHPVLLDAAFQAIGAAVNEELSIYLPVGLEKLVVYKNAPRSLWSYV
QVYTTNAPGSLKADVQLIAASGELVATISGLHLRQAQQALDVYRDWYQVEWQSEGRVRWI
PSLASVCDRLSPTVQNLVAQPEIQQYQKLLPQLEKLSISYVIDAFTSLGWQFVPNQYFST
SQLVEKLAIAPQYQQLCDRLLEMLAEEHFLRRHDDLWQVVALPQSTAPQLTESVELTLLD
RCGKELANLLQGKTEPLQLLFPQGDLTNATQLYQDSPAAKLMNTLVQQVVLALEKPHYRR
VRILEIGAGTGGTTAYLLPHLDPAVTEYTFSDVSPRFVHNAQQRFQEYAFVQYRVLDIET
PPQAQGFAVDRYDIVIAANVLHATCSLAQSLAHVQQLLVDDGVLILLESTQKLRSLDLIF
GLTDGWWRFGDRDLRAKHPLLSVAQWQQLLANCGFVDVAAIAPEPQSILLARKQVFCQWV
ILCDRLGLGEELARLLAQRGDDCVLVFAEEVDWRRVFEDAERGVRVVYLWGLDGETNHRD
AESAEGRSKGGLVGECRCVLELVRGLGDKSAGLWLVTQGAVMDVDRRGIWQSPLWGLGRV
IALEHPELGGFCVDLDPAVGVVEQASELCAVLVDSLPQVALRNQQCYVPRLVRYCSSLLE
VSEPFRLGMSTKGTLDLQFQPMMRNAPQAGEVEIRVRATGLNFIDVLDALGLLPFERDWF
GVECSGEVVAVGDGVEHLQVGDAVIALAPASFAQFVTTNAKWVVLKPHNLSFATAATIPA
NFLTADYALNHVAKIIRGKRILIHAAAGGTGMAALQLALQAGAEVFATASPSKWQQLQAM
GVKHVFNSRNIDFAAEIMVLTDGEGVDVVFNSLSGDFIAKSLSVLKPDGHFLEIGKRDIW
SQTQVQQVNPGATYTLIDLMSVAQQQPDRMQSMLRHLVSLFATSQLQVSPQTVFPIEKVV
DAFRYMQQAKHIGKIIITHYPLPLTSFPGTYIITGGLGGLGLLIANWLVEQGARHLVLVS
RREADAEIIQRIEMLKSAGAEILVISADVTDESQVSGVLSTIKSSLPPLRGVIHAAGVLD
DGVMQQMTWERFAKVLYPKMLGAWHLHTLTQDQPLDFFVLFSSAASLLGSPGQANHVAAN
TFLDALAHYRQAQGLPGLSINWGAWSVVGAAAKRGVAQQMRSRGIHEISPQQGLQSFAAL
LRQTAAQVGVVPIDWSTFLQHTNSDFFADFQTATQPKSPPQSVKVERPQQLKAYLQTEVA
QVLGLPISQLPALKQGFFELGMDSLMTVELKNRLETNLGVSIPASAIFEYPTIEDLAGYL
AEKLANNSDTNLQPKTEDNDDPNLTNADIISELAELETLLQGQTDESN
>F1TBP3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
MKKFLEFIFKNVANKELDSKIAESIIREHQAEMNDRPASENSIKDIAVIGMSCNFGKSEN
LQEFWLNIEQGIDCLEEVPEYRWDKEKRYSADRKALKSYSKWGSFAGRANKFDSDFFNQS
EISSMVTDPQQRLFLHLCWEALENAGYGSRDSRRGDDIGVFVGVRGNVYNTETFVSNKNM
SDMSRKDSIEFIRSVLLGKAPNMVAAAVSNYLDLKGPSMAVDTACSSSLVSIHLACQSII
NGDCDMSIAGGIEVIVDPNTYVYLSQINALSPEGKCKTFDKNADGYVPGEGGGAVILKSL
DKAIKDKDNIIAVIKGTAVNNDGYTVGVTTPDIEGQKRVIKKAYRKAGVKPDSVTLIEAH
GTGTFLGDPTEFRALTEVFRENTDKFNFCALGTVKSNIGHLHSAAGIASFIKIALALNKG
RIPATLNCNEPNPRFNLISSPFYISDKTTNWEVDKIKRRAGISSFGFGGTNCHIVLEEHP
SEYTKKEAETIENHLAVYSAKDNEALKRVICNNLEYLNSNFVQPEDYSYTLNTGRELFEK
RICVSFKNVEELRGKLSALIDDKEKQFSLSENAASKSSETPKTALVFPGQGSQYYGMAKE
LYIRAESFREAFNKCDTAFSKYLGQSIKEIIYSSDVSKDLINQTAITQPVVFAIDYSMGR
MWLDLGIKPDAVLGHSIGEYAAACIAGVFTLEEAARIVVKRAALMNSIDCNGGMMVVFAD
EATVRKVSGDTLPKLEAGISIAAINGPSNIVISGTNKDLEIVKSKLSTLNINTRELAVSH
PFHSKLMAPILEEFRNEFNSIKMKRAQIPLVSNLTGDFKYNFDADYWQEHIIEPVRFYQS
IVFLTDNNYDIFIEAGPGTTAATMLKRIEQCSQKVIIPTLNKYDSDWDSLTGAISTVIKE
GLEINFNVLYSKRNKIELPTYPFSYREYWINQERSSDIKHSSEEHKNTNGLAYALFDNIK
IVSENEIHLEKTVTTEDLEVIRNHVVGDNVIMPGVCFWEMAQIASLFGYGKVPVALKRIT
YPSALIIDKKENSRYRLILDKEKGKFTVSAYNKKSEQLWEQVALGTIEEVNTADNSLTDI
SGIKKRLNYRYFSGRELNEKFKEKGLFYGEKFYSVTNAWGGQNEALTELRFKADMLSENY
MYHPGILDGALQGIALVQEVAEDTRTFIPYRVEQIDFYGRLPEDCFGYVSLVKYNTEKGI
IEFNVSITDIYGNVKISIKKMCLKAVNMQSNEAIVTREKQIKEYYTPYWTEIEKEQIKPL
TLKTLLVFEDIKGKDSPLVKFYENRGCKVIKVSKEFSYKKINEDQYNINPYNKEDYQNLF
SSLHKDGIAAEGIIYAFDLNRQEVADNHFAAVEDMAGGKVLGLIALINSMRVYNLDETHI
AVVTSNAFIVNSHDKGYNYPQAAVAGLIRTIPHEYGNIKGVLIDIEENSLENERTLKLIA
DYLMNQYKKEIVSIRNGRLFAQTFKKENFCINQDMNLPLQDQGVYVIAGGLGGIGLEIAK
AIAAKVKARLILIGRSPFPERSKWQSHETEENKALLKKIKSIQDIEAKGSQVITLAVDVC
NEKQLTSALESIRTKFDHINGVINAAGILEDALINRVTKEVYEKVTKAKILGSCLLDYAT
NKDNLDFFVIFSAMVTYFGNAGQAAYSCANAFEDSFAAYRNFVKGKKTIVINWGVWEEVG
LVADSVSKKSLEERGIIPLSTSEAIEGFYSCLTEKHFQFGIGKLSKDLENKLISRLITTK
LSRSISNSLSGHFTMDIEKLLKEYLLKKINELRENSSKPMNYKTSFLDAGLDSITIVNFT
ENFENETGIKLYPTVLFEYPTIQELSKYLLKNNNSVLDKILNENLILGDEKTDYAEIENT
ETEVVSEKEQNLILSTDIAVIGMSGSFPGASNVNEYWQNLMNGINCVKEVPSERWDWREY
YHPDKQKGKTYCKWGGFIDEIDLFDPLFFNLSPKEATVLDPQQRFLLKATWETLEDAGYA
DGKLFGTRTGVFVGVSNHNYFDEAFDEDNNYSGLATANAIAANRLSYFFDLKGPSMSIDT
QCSSSLVALHEACKSIIIGESDYAIAGGVNFLIPKDYYILLSQMEAVSKDGSCKTFDKKA
NGFISGEGVGVLLLKRLSDAITDRDNIHCVIKATEVNHDGKSGSLTAPNSKSQSELIKRC
IGKAKVNPETITYIETHGTGTSLGDPIEIKGLTEAFTEYTDKRSYCALGAVKSNIGHLES
AAGMAGIIKVIMAMKNKTIPGNLHFEEKNAFIDFANSPFYVLDKPIKWQTYGNPMRAGIS
SFGMGGTNGHVILEQAPEYKKYDSSDENNVSYPVVLSAKSYSALKKSIIKLTEYLEDKPH
LQIKDISYTLNTGRYNFNYRVAIVAASVAELTYSLQQISSNNFEYWQSHKIFYGSTNGND
AISHLTASEDEIVKAVVVIPTHDRSIFNNIVKFTNKYFQKNRVFMEVLDEYEKAVNKIGM
SIKKCLQPEVVCLDNEAKIFTFAFTVSMIKFLETLGIKTVQVIAPDNSEIIMAASEKRRS
PEECIRKVLENNEEGTLNASQVIDSNYIINLGRRDYLDILGIPDEQAGIFNILEDESFDT
DSVNTLISKIYVKGGKINFNAIYSDSERKTSLPTYSFQPKSYWNRKKLKDVSREEIVAVT
EAKHDVQKAQDYFYKWFWQEVKENTPLTFENSFVWVVFCDKQELYANIRESLKTRNQKVI
LVFADDKYYKKDSCNYTINSYLEEDYKVLFKDIIKDFGRVDTVINLWAYTNTEFQETTYA
SVYGLLGIALGLNANLKGNTEVNLISITNHSLEVEDIDKGKISVGGYPVHMLSRLISAEI
KNIAARSIDFNGLEASKEVVEDVIFKYSLTKNGFSELAYRHGKAYIRMLKKNTLQKPEIL
NSVWKDGGVYVITGGATGIGAEIGLHIAKKVKAAVILIGRTKLPEKSEFREYLERGDQKA
VIEKIENIIKIQEAGAKVEYYNGDISDELKTIEILDNISKRFGHITGILHCAGAKRDGII
TAKSFKDFQYAIAAKVSGISNIKKAIEGKSVDFVVAFSSIAALYGTPGQSDYSSANALMD
AFINDWSGNTETFVTSINWTLWDGAGMDIPLLAKRKMENDGLLPLEISDGITALERLLQD
RKASNYIVMKLSESDKFIKDLFESKMRNPMSDKNGLFLSGTQSSKNMSVHKTTNTFEKET
KEFLLKMLSELLYLEATDIDTSRGLDEYGMDSLAIKEALAALEKQYDTVLEPSLFEENPT
IDKLVVYLADRLSKNIQYQTEEAFNNSGESEISEDIATDSDEDKIEHLLCKLYEGTINTK
DAKEKIARLLSVSED
>A0A0F4YK25|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Rasamsonia emersonii CBS 393.64|TrEMBL
MRTWLLSLHCDLCQALVTALLLPLTEAFTLVQYFSLNPVSNFTLFSNEPSPAGVLSLNLS
SSSSSLDMVTYTPSSEAQDLAHKLNVIYFSNEFPSDDLSYLLRRLHNHSKHRNHPILARF
LDEATRALRQENLEAIDAEAPDSWAYVVYGLTPEDAEKELDNIHTRDSTPAASRIFVSAI
SETSVTVSGPPSRLKALFRTSGFFRDRKFTQLPVYGGLCHAPHIYSLEDAQKVVQTPLLA
PRFKPVLPIMSTSTGQPFVASSAADLFEQVIFEIMTKQIVWDNVIAGVAERVTKTDARDV
TIMVFGVSLPSQQMSSALITTTPDLAVETEDLFVWVTTDVEEEKHEPRGSMQSKIAIVGM
SCRLPGGATDPEKFWELLEAGMDVHRKIPADRFDVESHHDPTGKRMNTSHTAYGCFIDEP
GLFDAPFFNMSPREAEQTDPMQRLALVTAYEALERAGYVANRTPATKLNRIGTWYGQASD
DYREVNTAQEISTYFIPGGCRAFGPGRINYFFKFSGPSFNCDTACSSSLATIQAACTALW
AGDVDTVVAGGLNVLTNPDAFAGLCNGHFLTKTPNACKTWDCQADGYCRADGIGSIVMKR
LEDAEADNDNILGVILAAATNHSANAVSITHPHAGHQADLYRQVMARAGIDPLDVSYVEF
HGTGTQAGDAEEMKSITDVFAPIKGKRRTAKQPLHIGAVKANVGHGEAAAGVTALIKVLL
MLQKSAIPPHVGIKNDINPGFPKD
>A0A8B4DMR5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus subsp. massiliense|TrEMBL
MDSAENPIESTPRFAIIGYAARFPGAADAEEFWDVLREGRDAISEVPADRWDAEEFFDPE
PGAPGKVVTRRAGFVEDVTGFDAPFFGMSTREVRLMDPQHRLLLETAWRAVEHSGIAPTD
LAETNSGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQGPSVAV
DTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSHAHMLAPDGKCKTFDA
AADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
DALKRAGVAPSEVGYLEAHGTGTSLGDPIEAQAAGAAYGIGREANDPLLIGSAKTNIGHL
EAAAGIAGVIKVILSLENELLPQHRNFQNPSPHIPWDRLPVEVVREARPWGRNGRPRIAG
VSSFGFAGTNAHVILEEAPVVSQDAVDAPAPAGGRKFSILPLSARTPAALAQLADQYRTW
LNAHPEAALADLCFTAGVGRAHLEHRAALVVNTREAAVELLGAVADDRPAPGLGRGESHD
TPKTAWLFTGQGSQYPGMARELFETEPVFADTLNRCAAAVADVLEKPLLDVIFDVDGPEA
EEALRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAEVFSLEDGARL
IAERGRLFGSLPAGGRMAAVFTDAERAERLTDEFPSLSVAAYNGANTVLSGPAQDLEKAI
AALVADGVRCDFLETSHAFHSALLDPILDEFEAYANQFNYKTPQRILIDNRTGTALGRSV
KLDGAYWRRHARQPVEFAKSVRTLADMNCKVLLEIGPQPVLTAAALRAWPDPATAPRAIA
SLRRNTADHRQITEAAADAYVLGHLPDFGAFQHGPARKLDLPTYPFERRQYWFSDKRDGD
NRDAGNRQQNSGGPRTEAVRLLEDGKIEELANLLGGVDGDQQTLNVLTKLAAQHNLQRTT
QTIADDRYQFRWEKSPTPLSGSQAAGSVTWLLVGDAAGAAQPLLDVLTARGQQHRALALP
VSDADEAQLVEALRSAAAEDSALRIVHVAALDPGQGSSSTQSLLRIQHQVLGGTRRLFRA
AAAAELRAPIWIVTQGAQHVIEGDAVAPEQSALWGFGRAAALELPQVWGGLADLSDAGAD
EWAQFIGRVSVSGEASTREDQLALRGQAVHVPRLVRREELPSGKPLEVRSDATYLVTGGL
GSIGLEIAGYLAGRGAKHLVLTSRREPGEAAQQRIDALAAQGCEVRAVTADVADGHDVAR
LLAGVQAELPPLAGIVHAAGEIGTTPLSDLDDAEVDRVFAGKVWGAWYLSEAAAGLKLDF
FINTSSIAAVWGGYGQTAYSAANAFLDGLAWRLREQGIAGTSVNFGPWSAGMADAESRAR
LEQRGIKTLSPADALAGLADVVAASGSNAAQGVIARIDWARFLPLYQQAGKRGFLAELDR
EVPSHLAGAAAGGQSGSTQLVERLANAPVQQRKKLLTDYLRDAVAEVTRVDVSEIREDAG
FFDLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLGDVLGLNEQAKPAAQ
LASAVTDRTDEPIAIVAVSCRFPGAPDPEAFWDVLSGGVDAIREVPEDRFDIDEFYDPDP
EVAGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYSPAAL
RGSRTGIFAGVGANEYAHLLSSESIDKIEPYFITGNALNAISGRVAFALGFEGPAVAVDT
ACSSALVAVHQAVQALHSGDCDLALAGGVNVLLSPVTVIAASRARMLSPVGRCKTFDASA
DGYVRSEGCGILVLKRLSDAERDGDRVLAVIPGSAVNQDGASSGLTVPNGGAQQRLIGSV
LARAGLVGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGGSREADRPLLMGSVKSNIGHTES
ASGAAGLIKVVLSLQNGVLPQSLHFDNPSPHIPWESLPVRVVDKAIPWQANGRPRRAGVS
SFGFTGTNAHVLIEEAPQPQATPEEDDASTPQSAPVNVLPLSARSPEALAAVAQRYESWL
AAHPDVDLEDVCLTAGRGRSHFEHRAALVVDSIQTAREGLLELAQNRLRPGVVRGEHTNH
PTTAWLFTGQGSQYPGMARELFDAEPVFAETVTRCAEAVKDIVTRPLLEVMFATDRETGG
KAGEALRHTSFAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSLEDGA
RLIAERGRLFGGLPAGGRMVAVFSDAKHVEQIAGEFPRVSVGAYNGPNTVLSGPGEDLEQ
AVARFQEEGIRCTWLETSHAFHSELLDPILDEFESYAAQVQFAAPTLPLVCNRTGAVLTA
QTPIDGQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAPPRA
IVSLRKGVEDRRQIADALASAYVSGHRPNFAALQRHPRRTVELPTYPFQRRRFWPKSSGT
AIEGGGGLPSGILGRGEDLASGDSVYISRLSVRSQPWLSDHVIYGTVVVPGATYAAMALA
AVGTPARAKDVFFYEPIILPEKSSREVQLTLHPLEDGSGSKFQVHSRPYGERDVDWSLNA
EGTVVTGIGDDAEPAPEAAEPAEPVDAAIERMERMRPMELFEIFADLELAWGPTWSGSLK
SLWLGEGEAIGDVLVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLP
LRYGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYLDRDGRHLGGIREFTVKRAPRE
ALLRGLGGDATRLLYTLGWHEVPVPPVADEGEESAASVGTWLIAGFDELAAKVPGCIPLN
RETDPELLGEVLVAAKERGVPFSGVVWRAAGPGATESTTESAARLEGEIAHLLSAVHTVQ
NSAQNGVKLPGGLWIVTERAVATESGEPVDPVQAALWGFGRTTINEEPALRAKLVDGDGS
PEAVQALARLLVTPVEEPEIAVRQGKLLASRLLPWSRTGHLTVPRGSDYVLAPTERGAID
NLRITEKEVPAPDEGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGIVTQLGEGV
TGVEVGQRVYGSMQGAFGSRFNVPAQFLAPIPDGISGVEAATIPAAALTVRLSFDWAQLK
PGDKVLIHAASGGVGLAAIQMAQQFGAEVFATASTFKRATLRKLGVKYVYDSRTTDFADQ
ILADTDGAGVDVVLNSLTSEGFIEATLRATAKNGRFAEIAKRDIWSTEQMAQARPDIAYE
IVALDTVMFQEPDRIRVLLTEVSEGLAKGEWRPLPAEIYPLTEARTAFRRMQQARHIGKI
VCQMPNPLAPRPDRTYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRAPDTDAQRVIAEI
TERSKTRIHVFTADVGEESEVVGLLNRIRAELPPLAGVAHLAGVLDDALLGQQSVERFRT
TLAPKAFGAEYLDRLTKGDHLDFFIVSSSVSSLFGSPGQSNYATANALLDGLIAQRRAQG
LPATGINFGPWGQGGMASSEAATANISAQGLIPLDPSAALAALAEVVANGTGQATILKAN
WQRAAKVLGSSRPPILDLVLPSAVGEVTGDSELLKQLMEIPVPQRAGFVTEFLQREVQNF
LRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVG
QLPDAESAEAPPAVESAEAESGTGPAAASDAVSELKE
>A0A2S9YVD6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Enhygromyxa salina|TrEMBL
MSDHPFTEGLVAIIGLACRLPGAPNPRALWQLLISGQDAMSQVPPDRWRATDYVDPDRRA
PGKMVTAVGGFLAAVDGFDPEFFGISPREAVQIDPQQRLALELCWEALEHAGVAPDHLRD
SDAGVFMGAMWNDYEKLHAIEDIEQHSGTGWHLGVVPGRVSHALHLRGPSMAVDTACSSS
LVAVHLACKALLAGETSLALAGGVSLMLTPHVGVAMSKFGGTSATGRCSAYDARANGYVR
GEGGGVVALRRYEDAVASGDPILAVIRASAVNNDGHSEGLTVPSEAAQRSLLRDVYARAR
VDPSSVSYVEGHGTGTAIGDPIEARAIGSELGRGRQRPLWLGSIKPNIGHTEAASGVASL
IKVVLSLRAGVIPPNLNFAQPNPAIEFDALQLRVPTRAQPWPGVQLAGVNSFGFGGTNCH
LVVSGFERAAGPQELDQPDRHYLIAVSARSAAALDARLQQLRELAQAGALCVADLAHTLW
HRRAHLEHRAVVVARTLAQLDERLGEPQRAQLGAADPRLKLAFVFSGQGSQWLGMGRELL
RVEPVFRAALAECSTIMQPMLGWSLIELTEHDQLEAHLRHVDGIQPAIYAMQVALAQTWR
GLGVIPDAVVGHSMGEVAAAVAAGAITVSDGALITCSRAALLRRISGRGGMLSVAIGATA
TEQLLAESPQRYAGLGVAVDAGVGSTVVSGGLDALARLREDLEARGIECRSVAVDVAAHS
PQIDALADELLAAIAHIRPRENDVRMISSVTGGEVDYRELQPAYWVRNLRNRVRFAEAAN
HLFEAGHSVFVEVSPHPLLTWPLRQIAKARGLEPVTVVGSMRRARPDHEVLLEALAALHN
RGVTVALEQPGALVELPAYPWQRRRFWPRPRALPQPADRRAAEPDVVASFEPSRIAALAG
HAVGGRSIVAAGVVLELVLRAWAMVESDSHVWVKIEQLEFAAPIPGDRRVRLELRGSALS
LGPAGSVFGRVAKSAHQAVRSAPASFELVTEHDAAQHYRALAERGVDYQPSLRAVESVQL
GRGSARARVARKQTRAALLDAAFQAVLAAVGEDGRFVTAALGVAELDSARLTTTREIRAE
VASGGGAGQLEGHAWLLDSHGAVVAELSGIRLALMPSETSVLRRRRWRPLGPITPAPRVS
STLGYVVWGPDQPSRAAVLDALAARGVPARGDAALSLDRAEQLAGIIVVFGSADTCHAAT
VAACERLIAAARACVERGVSLELVVVTERAHWITEDAPATIGASALWGLARVAVAEHPGL
RLRALDLGDLRDPAQRAGLVDELLAGPGADRQRSLALRPGVDGLARLVATLEPEPVASHG
WAPPRAGAVIVTGGLGGIGRAVVTWLVERGVERVVILGRRTLDHAGAAFIDELVSGGHSQ
LRYLAVDVAEAAALRDALANELAQVIGVIHSAAVLTDAPLLEHDAAQLHAALRPKLLGAW
NLHQLTEARELAFFVMFGSLGGWIGLPGQASYAAANAALDGLAEHRRALGLPAVSVGWCG
WRGLGFARSAGGAASLDRLAADGIGSLDAERALSLLDHLLTSDAAPVVAVMPPAEVAEVA
SVDADDRLAELRALVPARRRVVVGDRVLAEVAAVLREEPQRVDVGRPLKDLGLDSLMSVE
LAERLARVLGVTTDPTLIWRHPSVDALVEHFVNELAEPGVVAEPRGAADQPDPLVAQLDE
LSEEDVLAMTRAIAPASTGSSRGVS
>A0A5P9PXC9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Amycolatopsis sp. YIM 10|TrEMBL
MDNEQKLRDYLRRASADLRRTRQRLNEIEAASQEPIAIVGIGCRYPGGVRTPEQLWEMVI
AGKHGITEFPADRGWNPEMLAMSNTRSGGFLHDAPQFDADFFRISPREALSMDPQQRVLL
EVTWEALERAGIDPTSLKGTQTAVFVGAMAQDYQVGPGEGGEGFQLLGNSNSVLSGRISY
TYGFVGPAVTVDTACSSSLVAMHLATQSLRNGECELALAGGATIMSSPTTIVEFSRQGGL
SPDGLCRSFAESADGTGWAEGAGVLVLERLSDAQRNGHEILAVLRGSAVNQDGASNGLTA
PNGPSQQRVIQQALINSRLSEDQIDVVEAHGTATTLGDPVEAQALLNTYGKHSRNRPLLL
GSIKSNISHTQAAAGVAGVIKMVMSMRHGVLPKSLGIDEPTSHVDWTAGAVELITENTPW
PETGEPKRAAVSSFGISGTNAHTIIEQAPELVIESEAPEPVEAGAVPVLVSGRNAEALRA
QADRILSILDDETSVLDLAFSLATTRASFEHRAVVPSANLRAGLTALAAGEAAPGTITGT
THSRSKLAFLFTGQGAQRLGMGRELYGRFPVFAAALDEVLEHLDVRDVMWGEDADALDQT
GNAQPALFAIEVALYRLAESWGLKPDFLAGHSIGEIAAAHVAGVLSLEDAAKLVAARGKL
MQALPAGGAMVAIQATEDEVAPLVTEGASIAAINGPNSVVVSGDEEAVEAIVARFEGRKT
KRLSVSHAFHSPRMDAMLDDFRAVVAELDLQAPLIPFVSNLTGELARVEQVTSADYWVDH
VRQAVRFADGVVWLRGHGVGTFLELGPDGVLSAMVQEILDDVTAVPVLRAGRDETETGTT
ALATLHVNGIPVRWSEYFDRTGAVRVPLPTYAFQTKRYWPKGGGFGFGGDPRSSGLGAAR
HPLLAAAVSLADSDGALLTGRLSLHTHAWLADHVVSGRVLLPGTAFLELAIRAGDEVGCD
RVEELTLTGPLVLPEQGGVQVQIWVGRPDQAGRRTVDIYSRLDTDDEQPWTPNATGVLTA
EAKRVPFDAKEFPPKDAQPIDLAGLYDRLAVDGFAYGPSFQGLRAAWQLGEDVYAEVALP
EDVDNESFELHPALLDAVLHASRFVEFGPESQGGLPFSWEGVSLHATGASTVRVKLSPVA
DDAMSIAVADAAGEPVASVETLVLRAVATEQLNVTVGRDSLFRLDWVAAQHATTEPAAVE
ATDLTSIVDVPDWVLYHVETSGDTVEAAHAVSAHVLGVLQEWLADERFADSRLVFVTRDA
VAVVEDDLPDVAAATVWGLVRSAQSENPGRFGLIDTDADSPLKKAIGVDEPQLAIRHNKV
FAARLARSLPQQREFDWDGQVLITGGTGGLGSVIAKHLAGEHGVRDLLLVSRRGPAADGV
DELVAELAELGAEARVAACDVTDRDQVAELVAQHDIKAVVHTAGVLDDGTIGSLTPERLD
TVLRPKADATWYLHELTGDLSAFVVFSSAAGVFGNPGQGNYAAANAFLDALAARRRAEGL
PAASIGWGAWEQTGMLSGADAERMARSGMPALTVDQGVALFDAALTAEDAAVLALRLDLS
VLRAQPEIPPLFRGLIRTRSRRSAVASSEAADTLVRRLSGLGEDERRDVLLELIRDQVAA
VLGHADGAEIEPDRQFKDLGFDSLTAVELRNRLTAVTGLRLPATMVFDYPTPNVLAGYLA
GELFEADAVIPEQARPATLTGDDPIVIVGMGCRYPGGVASPEQLWQLMLDGEDAISGFPT
DRGWDLEKLYHPDPDHPGTSYTRSGGFLHDAGEFDAGFFGMSPREAVATDSQQRLLLEVS
WEAIERAGIDPVSLRGSQTGVFAGVMYNDYGGAMGGASEGYQGSGTSPSIVSGRVSYTLG
LEGPAVTVDTACSSSLVTLHLAAQALRNGECSLALAGGVTVMSTPIALIEFSRQRGLSPD
GRCKAFSDSADGVGWSEGVGVLVLERLSDARRNGHEVLAVVKGSAINQDGASNGLMAPNG
PSQQRVIQQALASAGLTTSDVDAVEAHGTGTSLGDPIEAQALLATYGKHRERPLLLGSVK
SNLGHTQAAAGAAGVIKMVLALKYGVLPKTLHIDEPSSHVDWTAGDVELATEAKELADVG
RPWRVGISSFGISGTNAHVILEQPAPVVVEERPTLDGVVPWLLSGKTRDAVRAQAARLLS
YVDDKPELEPADVAYSLATARSAFEHRAAVVGEDRDALLRSLAALAADSPDAGVLTGESG
SGKIAMLFTGQGSQRAGMGRELYQRFPVFAEAFDEVADALDAHLERPLREVMWDSNDAET
GLLDQTGWAQPAIFAVEVALFRLVRSWGVKVHFLGGHSIGEITAAHVSEVLTLADAAKLV
AARGKLMQALPAGGAMVAIQATEDEVAPLVTEGASIAAINGPNSVVVSGDEEAVEAIVAR
FEGRKTKRLTVSHAFHSPRMDAMLAEFGQVVAELAFAAPKIPVVSNLTGHFDTDAMSSPD
YWVRHVREAVRFADGVRTLHDSGVRTFLELGPDAALSPMVQEVLGEDAGNVVAIQRAGRG
EEATCVTALTRLHLHGVQVGWPSFFDGRGVRRVDLPTYAFQHSYYWPQAPEPPAFSADPS
DERLWAAIERGDADELAALLHLGEQQQSSLDELLPALSSWRQSNQQKSQLDSWRYRVKWS
PLRTGVTPVLSGQWLVLTGEQDAELAGQVRELLAAHGAEARQIELDAECAEQGPITERLA
GLGDIAGVVSLLALDDRPYEPHPVLSTGLALTISALRTLDAPLWTLTRGAVSTGQGDEVE
SLPQAAVWGFGRVAALEYPQRWGGLVDLPSEADSAVLRRLIGVLTGDEDQAAIRATGVLG
RRLARRPVDALPAADEFAAGGTVLVTGGTGGLGAAVARWLAGRGAENLILTNRRGMDAPG
AAELRAELTELGARVEIVACDVADRDALAAVLDGIPPAMPLTGVVHTAGVGQSAPLELTG
LPEFADVMSAKVLGARNLADLLGDRELDLFVLFGSIAGVWGSGGQSAYAAANAYLDALAE
SRRARGLTATSIAWGPWAEVGMATHEEMSGSLLRQGLAFLDAGPAITELHRAVVQADVTV
TVADVDWSRYHPLFTSRRPSALLSELPEVRALAEAEQKQAGESSTFANELRELSEAEQHR
RLVALVRAEAAAVLGHSSAEEVGEQKAFQEIGFDSLTAVELRQRLGGATGLTLPATLVFD
YPTPKVLADHLHAELLGSAAEAVVYQANHGGTTDEPIAIIGMACRFPGGANTPEEFWQLI
AEGTDAITEFPGDRGFDMAMLYDPDPDNPGTTYSTAGGYLHTAGDFDPAFFGISPREAVG
MDPQQRLLLETTWEAIERAGIDPASLRGTRTGAFIGSSYSEYGAMDGGGSEGYAVTGSSP
SVLSGRVSYVFGLEGPAVTVDTACSSSLVALHLACQSLRSGESTLALAAGATVMPNPKPL
IAFSRQRALAKDGRCKAFSDSADGMTLSEGIGMLLVEKLSDAERNGHPILAVVRGSAVNQ
DGASNGLSAPNGPSQQRVIMQALANAGVAPSDVDAVDAHGTGTTLGDPIEAQALLATYGA
ERDPERPLLLGSVKSNIGHSQSAAGVASVIKMVMALRHGMLPRTLHADTPSSHVDWSSGA
LSLLNEPASWVPNGRPRRCAVSSFGVSGTNAHAVLEEAPPVSAEPAPVVIEQPVPVVPWV
LSARSEAALEAQIANLLPAVEGERPVDVGFSLATTRSKFEYRTVMIGSSEVRGLADLDAR
TTFVFPGQGAQWAGMGAQLIDESPVFAARIAECAAALAPYLDWSLLDVLRGVDGAPSMER
VDVVQPASFAVMVSLAEVWRSYGVIPDAVVGHSQGEIAAACVSGALSLEDAAKVVALRSQ
AIARELAGRGGIASIALPADEVTGRLAAWDGRLSLAAENGPRTVAVSGDPEALDELLETL
AAEGVRVRRIVVDYASHSAHVEDIRDEILRDLHGLDPQRPRIPFLSTVTGEWVDGAELTA
DYWYRNLRQTVHLAGAVRDLVTAGHRAFIEVSSHPVLTVGVEDTLADAGERGVVAGTLRR
DLGGLGRVWTSLAEVFVRGVAVDWAAAFEGTGARRVPLPTYAFQHERYWVGGPQMPEQPT
GADPVDTAFWAAVERADLATLTSSLHVDEESLAAVLPALNSWRRQHREQSTADSWRYRVN
WKPLSGGQASLSGTWLLVTAEGVEDEDVFAALTEHGAEVRRVVFDGSTVDTEGVTGVVSL
LSMAEEPSETEPALARGLELSVKLVQNCEAPLWFLTRGAVSTGRSDKLTNPVQAQVMGVG
WTVALEHPQRWGGVIDLPERLDSRAGQRLAAALADPAGEDQLAIRASGTLARRIVRAPAR
PNRAREWQPRGTTLITGGTGTLGPHVAHWLAHQGAERIVLISRSGIEAPGAPELVAALQE
LGADASAVSCDITDRDAVSAMLDGLRADGHQIRNVIHTAAVIGLHSLAESTSDAFGQVVN
AKVRGAEHLDALIDEELDSFVMFSSISGMWGSGQHGAYVAANAYLNALAENRRGRGLPAT
AVSWGIWADDLGLGRVDPEQIRRSGLVFMKARLALSALGRALDENDTDVAIADVDWNRYH
PVFTATRPTTLFDEIPEVRQLTEEAANAAPKDDGGFADRLRSLPAAEQERVLLDLVRTQV
ATVLGHSSADELSEHRAFREIGFDSITAVDLRNRLAAATGLTLPTTMVFDHPNPIALVEF
LLGEIEGGGRSIAPVVTSAVDDEPIAIVGMSCRYPGGVSSPEDLWELVLGGVDAISGFPA
DRGWDAGALFDPDPDRPGGTYSVQGGFLHDVANFDPGFFGISPREALAMDPQQRLLLETA
WEAFERAGIDPASLRGSLTGAFIGASYQDYSTGGTDAAGASEGHMITGTLSSVLSGRVSY
LFGLEGPAVTIDTACSSSLVAMHLACQSLRGGESSLALAGGVSVMSTPGAFVGFSRQRAL
AQDGRCKAYSDAADGMTLAEGVGLVLLERLSDARRNGHEVLAVVRGSAMNQDGASNGLTA
PNGPSQQRVIMQALANAKLDPSEVDAVDGHGTGTALGDPIEAQALLATYGQATGRQLLLG
SVKSNIGHTQMASGVASVIKMVLALRHGVLPKTLHVDQPSSHVDWSTGAIQLLTESTPWP
ETGRPRRAGVSSFGLSGTNVHTILEQAEPVEAPAPITESGPMPVLVSARSEDALRAMAGR
LLSTVEDQHLTDVAAALATTRSTFEYRAAVVAEDTAELVRGLTALRDGQPGAGLVRGTAA
RGRLAFLLTGQGSQRAGMGRELYDRFEVFADALDAVLAHFDTELDRPLREVMWEDGPALD
ETGYTQPALFALEVALFRLVESWGVKPDFLAGHSIGEIAAAHVAGVLSLADAAKLVAARG
RLMQALPTGGAMVAIEATEDEVTLTDGVSIAAINGPNSIVVSGDEDAVDAVVARFEGRKT
KRLTVSHAFHSPRMDAMLDDFRAAIADITFEAPQIPIATTGDVTSVDYWVGHVRDTVRFA
DSISWLAGEGVRNFLELGPDGVLSGMARESLGEDALLLPALRRDRPEVTALLGTLTGLHV
HGVRVDWAGFFARAGGRRVELPTYPFQHQRYWPETSAAEAPVDAADSVDAEFWSAVERAD
VASLARTLDLDGDTVTAMVPALSTWRRKRQELSTVDSWCYAVTWKPVEAGTKPLIGPWLV
LAPVADERATTIADGLGVETTLVEVTGDDRTALAERLRDLGVADTRLGGVLSLVDLTATA
AVVQALGDTGIDAPLWCVTTGAVSVGRSEALTEPEQAAIWGLGRVVALEHPDRWGGLLDL
PGELDRATLRRLPGVLAGDEDQVAVRPSGVYARRLVHRPAGPEPRTSFEPSGTVLVTGGT
GGLGRHIARWLLDNGAEHLLLLSRRGPDAPGAADLADERVTIKACDVADRDALAAVLAEH
PVSAVIHTAGVVEDGLVDALTPESFDAVMRSKAIAAKNLHELTGELSAFVLYASTAGVIG
AAGQGNYAAANAYLDALAEHRRGLGLPATSIAWGPWAEGGMVADSADAVANRLRRGGLSP
MAPEPAISALKQAIEHDQTTLVVADIDWTRYYPALTALRPAPFAADLPEVRRMREVGSAG
TGTVERPAGHELAELPPAERSRKVLEMLRTQVAAVLGHADASEVEPDRAFSDLGFDSLTT
LELRNGLAAATGLTLPASLIYDYPTPRALAEHLLGELLGAVDQPVTTAVATRPVDDDPIA
IVGIGCRFPGGVTSPEELWELLAEGRDGVTAFPDDRGWDLGMLAQGASATREAGFLSGVA
DFDATFFGISPREALAMDPQQRLVLETAWEALERAGIDPSKLRGSQTGVFVGTNGQDYPS
VLRRASADVQGYVATGNTASVMSGRLAYNLGLEGPAVTVDTACSSSLVAMHWATRALRAG
ECGLALAGGVSVMASPDSFIEFTTQGGLAADGRCKAFAEAADGTAWAEGAGMLVLERLSD
AIANGHQVWGVLKGSAVNSDGASNGLTAPNGPSQQRVIRQALADAGVSTAEIDAVEAHGT
GTTLGDPIEAQALLGTFGADRDEPLWLGAIKSNIGHAQAAAGVAGVIKMVLAMRYGVLPK
TLHVDAPSSHVDWSAGAVSLLDEARPWPVSDHPRRAGVSAFGVSGTNAHVVLEQAPVIEA
EVAPAAVTPTVVPWLVSGRTKEALAAQTERLRDFAARHPEESTVDIAYSLATTRSAFAHR
AVLLVTGGEVTEGARASVRRGDGQTAFLFTGQGSQRIGMGRELYDRFEVFADTFDAVAAH
LDVELDRPLREVVWGQDAELLQQTGWAQPALFAIEVALYRLATHLGLRADRLAGHSIGEI
AAAHVAGVLSLEDACTLVAARARLMQALPTGGAMVAIKATEDEITLTEGVSIAAVNGPSS
VVIAGDEAEVLEIAAGFEKTSRLKVSHAFHSPLMDPMLDDFRAAIEGLAFHEPRIPVVTT
GDVTTVDYWVNHVRDTVRFADNVRTLAEAGVTTMIELGPDGVLAAMVTEEALVVPLLRKD
RDEELALTAALGTLHANGVDVEWANYFTGTGASRVELPTYAFQRERYWPEGTIAMGPPEA
DPADAEFWAAVDRADVDSVASTLELDGETVTAMVPALSSWRRRRREQSVVDGWRYETVWT
PISAGTELAGRWLVLLPAETAEDEWTSDVVEALGGNTVCLDVRSRAELAGLLLEVNDSSF
DGVVSLLATEGSEVPDHAWPAEQLQVLGEAGVTAPLWCVTRGAVAVGDEVAENFGQAAVW
GQGRVAALEHPDRWGGLVDLTTANGLAAVLAGTENQIALREHGIFGRRLVRAAGAAGSWT
PEGTVLLIGGNEQLATWLARGGATVITGTAADLAEHDVTAVVHAGAEDLESVRELDELAG
DRPLDAFVVLGSIAGVWGVRGRGPQAAVDAYAEAVVRARRARGATALHLAWGPFAETPES
QLGRHLRLSGLPGMDVELAFAALGRAVAAGDTSVTVADVRWETFAPSLPGPLLADLPEAS
AAEESDVDSSELRQRLLSLPAEDRADALLAVVRAKIAVVLGHSTTDAIEDGSPFRDLGFD
SLTSVDLRNQLNTETGLSLPATLVFDYPTPAELAAYLLEELLGTGAEQTNVVQVTGAVTD
DPIAIVGMACRFPGGVRSPEDLWELVTGGVDAVGEMPADRGWDFEKLFGAKQSITRQGGF
LYDVADFDPDFFAISPREALVMDPQQRVLLESAWEAMERAGIDPGTLRGTDAGVFIGGGS
GEYRLPAETAGHEWQTAQSASLLSGRLAYTFGFQGPTVSVDTACSSSLVSLHLAAQALRN
GECSIALAGGVTVMSTPVGFVEFSAQGALSEDGRCKAFADTADGTGWSEGVGMLVVERLS
DARRNGHEVLAVVKGSAINSDGASNGLTAPSGPSQQRVIRAALAGAGLGTSDVDAVEAHG
TGTKLGDPIEAQALLATYGRDREQPLLLGTIKSNIGHTQSAAGVAGVIKMVMAMRNGQLP
RTLHVDRPTTQVDWSAGSVRLLTETTPWPEVGRPRRAGVSSFGASGTNAHLILEQAETVP
PTEAVAPERKPEVMPVLVSGRTPAALRAQANRLLDLARENDDLAGIALSAATTRASFEHR
AVVLAGQQGELVDGLVALAEDAVAPHVVRDEAARSGKLAFLFTGQGAQRIGMGRELYNRF
PVFAAALDEVLERLDVRDVMWGDDQEALNQTGHAQLALFAVEVALYRLLESWDIKPDFLA
GHSIGELSAAHVAGVLTLDDACALVSARARLMQALPAGGAMAALQASEEDVLPYLVDGVS
IAAVNGPNSVVVAGDAELVDKVAEPWKAKRLKVSHAFHSAHMDPMLDEFRTVAEGLTYSA
PRIPIATEGDVTSPEYWVRHVRDAVRFGDAMRNLDGRGVATYVELGPDAALSAMARESIS
AQALVVPVLRKDRGEENSLVSALARVHTRGVRVGWREFFAGVGAARLDLPTYAFQRQRYW
PDAVPTAPKVETDGVSDQGLWEAVAQQDFASLESVLDVDSESLSKVLPALLDWRRQREDQ
SVVDSWRHRIGWKPLGGKKTDRLDGTWLAVVPAGRGEMLDALDAEFIRVEVDAPDREQVA
EALEAHSGTTFTGVVSLLALAESAGGGAPAGVLLTATLVQALGDAGITAPLWCLTSGAIS
VGRSETVPNPEQAAVWGLGRVAAMEYPERWGGLIDVPAQLDDRVVRGLTSVLSGLDAEDQ
VAVRTSGIFGRRLLPAPAPTPAREWEPSGTVLITGGTGALGGHVARTLAEAGARHLVLVS
RRGPEAPGAEELRTELAGLGAAVTVAACDVADRAAVTELLGDIPDLTGVVHAAGVLDDGV
LDRLTPDRFQDVFRTKVDSALLLDELTRELDLSAFVLFSSASSAIGNPGQANYAAANAVL
DALAERRRADGHAATSIAWGAWGGGGMAGTDQAVETARRAGVAMMEPELACQVLRQLAAE
SEPTAVVAAVDQSRFASGGFRPSPLMRELAPAQGPAAETAPAEPALAEQVLKLAPARRYE
VVLELVRTRAAEVLGQADLDAVREDRPFRDLGFDSLAVVELRNQLNAATGLSLASTLVFD
HPNPKALAEHLLEQLVPDGAVGDSEEAEVRELLASVPLAKLREHGMLDQLLRLARPGGGA
EENGESASIDTMTVDDLVQAALSGQDGHDDQSDLSWK
>A0A2K8P8M2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces lavendulae subsp. lavendulae|TrEMBL
MQNQHDDLSGQNENEQKLLDYLKRVTADLKQTRRRLHEVEAKDQEPIAIVAMSCRYPGQV
DSPEALWRLVESGSDAVTGFPTDRGWDLDGLYDPDPGTPGKCYTREGGFLHEAGRFDPGF
FGMSPREALATDPQQRLLLEVAWEAFERAGIAPTSVKGSRTGVFVGLAYQGYAGSGDTRE
ELEGFLLTGTAPSVASGRVSYTFGLEGPSLTVDTACSSSLVALHLAVQALRQGECTMALA
GGAAVMAATGMFTEFSRQQGLAVDGRCKSFAAGADGTGWGEGVGMLLVERLSDARRLGHP
VLAVVRGSAVNQDGASNGLTAPNGPAQQRVIEQALAGAGLSPADVDVVEAHGTGTRLGDP
IEAQALLATYGRGRSAERPLWLGSLKSNIGHTQAAAGVGGIIKMVMAMRHGVLPRTLHAE
EPSPHVDWSDGTVRLLTEPVAWGEDGRPRRAAVSSFGVSGTNAHTIIEEAPPAPEAEEPP
SGQDRTDPLTGPAPVAWTLSGRNGAALREQAERLLTHVLGLGDVSPVDVAHSLATSRAAL
EHRAAVVGTDLPALVAGVRALAEGTAAAQVVEGTGGRDGDTAFLFSGQGSQRLGTGSELH
ASFPVFADAFDTVCSALDPHLERPLKGVVFGEDPGLLDRTAYAQPALFAVEVALFRLVES
WGVRPDFLAGHSVGEFAAAHVAGVLSLDDAARLVAARGRLMQALPAGGVMVAVQASEAEV
RDLLAGYEDRAGIAAVNGPSAVVVSGAGEAVAALVDRLSADGRKTKALTVSHAFHSPLMD
PMLDDFRQILETVTFEAPRVPIVSTLTGGRVSAEEFCSVGYWMRHVREAVRFADAVTSLA
DEGVGTFLEIGPGGVLTAMAQAVLEDADAAVIPVLRADRPEGLAVTTALARLHVHGIPVD
WTALLAGRGARRVDLPTYAFQREQYWLETAPAAGGRQSTIEDWQYEVTWQRLPDPATDPA
TVTADGHWLLVLPAGTDHDGATERDAAGLRDALAAHGCAVTSLTVDAAEDRETLTARLRG
ATDATPPRAVVSLLGLDERPVEGLAALTGGVAATLTLLQALGDAGVGAPLWCATRGAVST
SPDDHPVTAPGQAQIWGLGRVAALEHPGRWGGLLDLPPHRDGPVPDRILAALTAGGPEDQ
LAVRADGVFARRLSRAGRNDVRTAGEWRPRGTVLITGGTGALGGHVARLLAARGAEHLVL
TSRRGPAADGAGELRAELEALGARVTLAACDVSDRDALSRLLTGLTDPAGTDGPLTAVVH
TAGVDTTALLADTDPAAFAGVLAAKAAAAVHLDELLDALPGGPAELDAFVLFSSIAGVWG
AGGQAAYSAANAHLDALAAARRARGLPATALAWGPWADAGMAAGPGIAENLRRRGLDPLA
AASALTVLERAVARNATAVTVADVDWARFAPAFTVGRPSPLLADLPEVREAAVARPGHPD
GAADTTDALRRALDRADPAERDRTLVELVRAEAASVLGHPGPEAVEPGRAFRDLGFDSLT
AVELRNRLVKATGLRLPTTMVFDYPSVLDLAGALLVELLGTADTAGSAAAPVRADDEPIA
IVAMSCRYPGGVRSPEELWRLVDEGTDAMSVFPDNRGWDLDALYHPDPDHPGTTYARAGG
FLYDLADFDAAFFGISPREATAMDPQQRLLLETSWEAFERAGIDPASVRGSRTGVFVGSG
YQDYIRRGIAVPEDVEGYLGTGNAASVASGRIAYTLGLEGPAVTVDTACSSSLVALHMAA
QALRQGECELALAGGVTVMSSSGAFVEFSRQRALSADGRCKAYSADADGTGWGEGVGMLL
VERLSDARRNGHRVLAVVRGSAVNQDGASNGLTAPSGRAQQLVIRQALANAGLSAADVDA
VEGHGTGTRLGDPIEASALLATYGQDRPADRPLWLGSLKSNIGHTQAAAGAGGIIKMVQA
LRHGTLPRTLHAGEPTPHVDWSAGAVRLLTEPIAWDPAEHPRRAAVSSFGMSGTNAHVII
EEAPEAGEAPEAPQPGPEEPAPRPPAGAAAVPLPLSARTGAALEQQAGRLAALLREDGTR
PRDIGYALATTRTLFDERAVVVGGDREEMVAALEALASGGSHELAVRGSAGSPAQPVFVF
PGQGSQWAGMATGLLDTSPVFRDRITACGEALAPYVDWSLDDVLRGADGAPALEGPEVIQ
PVLWAVMVALAELWQACGVRPAAVVGHSQGEIAAAVVAGALTLEDGARLVARRSALLARL
AGRGGMVSVPRSEAEVTERISAWDGRLAVAAVNGPRTVVVAGDPQALAELVDACAADGVQ
AKRVRVDLASHCAQVEEVREELAAELAPLVPNAPRIPFCSTVTGDLLDTAPDAAYWYRNL
RRTVRFEQAVRRLRADGHRVFIEISPHPVLVYGLQDTLDDARTDGAAEAVVPTLTRSAGD
ARRFLASLGEAHAHGVPVDWPAVFGGPTGTPAELPTYPFQRQRYWLDAPDAAAGTAPAPQ
SAADAEFWAAVEREDLASLTEELRFDEDTTLAAALPALHAWHRGRRDEAATRAWRYRIDW
KPVPDTAQPSLTGRWLAVVPRDRFEDPAAELALDALAAHGADTVRLAVTGDEDRQTLADR
LREAGPGVRGVLSLLALADHAHPDHPAVPLGLATTLLLVQALGDADVDAPLWCVTRGAVS
TRPADPVHAVPQATVAALGRVVALEHPGRWGGLVDLPADVGATATWTGRRLAAALSGATG
EDQIALRADGAHARRMVRATDTATDTDSPAGPGWQPRGTVLVTGGTGFIGSRVAHWLAAA
GAEHLVLTSRRGPAAEGAEELRAELEALGARVTLAACDMADRTAVSALLESLAGLPPLSA
VVHAAGIGTPALLADTTVAETAEVMGAKAAGAAHLDALLGDRALDAFVLFSSGAAAWGSG
AQSAYAAANASLDALAEHRRARGLAATSIAWGAWGGGGMVDRAAEERLRLRGLDPMDPGL
AVLALRRAVDHGDTSVIVADVDWKRFLPGFTAARPSPLLGGLPEVVLLLAAEETGADAES
GGEPLLVRRLTGLPATERDAAVLDFVRSEAAAVLGHLSAEAVRERDVFLELGFDSLTAVR
LAKRLGGATGLKLPSTLVFDHPTPEAVATRLLALLAEASGGPHGAGPAPRDGQDDLLVGL
YRRAGELGRLSEGIGMLTAAARLRPVFDAASAADHRPVPVRLAHGDEGPPLICFGPYMAP
SGVHQYARFAAAFGGRRTVWALPEPGFGPGEALPQDVAALVEVHVRAVADCAGEEPVVLV
GYSSGGWVAHAVACRLEELGRPVEGIVMLDSFTREEGMADRFQSAVVREQSERFDFISAP
GTQLTAMGGYLAVFEDWDAPVAEAPTLVVRAEERMADGAEGTDDRPPAPEHAQQVTEVPG
DHYTLMERHARTTATAVDEWVLKLP
>D2Q990|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Bifidobacterium dentium (strain ATCC 27534 / DSM 20436 / JCM 1195 / Bd1)|TrEMBL
MRAVYAAGVDYDDPLSVLEVGERPEPQGKPFWSTISVHASTVNHHDVWSLQGVGLSADAT
PMILGTDAAGVLEEDIPVRKGLKAGSEVVLYTFIGTDGAGVMPGERRTILSEKYAGTMAE
LTQVPSANVFAKPSNLNLDEAAALGTSWLTAYSLLFTSANVKPGDTILIQGAGGGVSTAA
IQLAHAAGLEVFVTSRSEAKRAKAVELGADAAFEPAARLPRKVDAVIESVGAATWSHSVR
SVRPGGTIAICGATTGDQPGAELTRVFFQDIRVQGNTMGSREDFARLLRFVEHADLHPVI
DSTFALADARRAFAKVIDGDVFGKIVLHI
>D0LS48|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2)|TrEMBL
MSEQREDASADTDTLLKRALTQIRKLRARVRSLEDAAPSPSTAVEPIAIVGMGCRFPGGA
EGPDAFWELLCDRRDAIIEVPANRWDADAFYDPDGTRLGTMVTRWGGFISDIGAFDRRLF
GVSRGEAESMDPQQRMLLEVAWHALEDAAIGPHRVRGSNTGVFVGICNVDYLRLMSGPPP
RGATGTAQSMAANRLSYHYDLRGPSVVVDTACSSSLVALALACDSLAAGRIDLALAGGAN
AVLAPDLTVALSEAKMMSPSGRCRTFDARGDGYVRGEGCGLVALKRLSDALADGDPIRAL
IRGVGCNQDGRSNGLTAPNGESQRALILEVLRRARVAPEEVSYIEAHGTGTPLGDPIEVE
ALAATYGRPRPDGEACMLGAVKSNIGHLESAAGIAGLIKAVLCLQKQRFVPNVHFEVLNP
NIELRGTPFAIPTESQPWPRAETPRRAAVSSFGFGGANAHAVLEEAPEHAAASDSAAAAG
ARPQVITLSAGSPAALRALAGRYVSHLGERPGCALADFAHTVQIGRAPLAHRAAFVARDR
DQLVRGLESCAAGGEAGGDAGGVSADRAVLHHGEVTRGARGRVAFLYTGQGAQHLGMGRA
LYEAQPVFRRALDECAELANPHLERPLLEVMFASPDDASSAEALTQTNYAQPALFAYEHA
MSALWRSFGIEPAAVIGHSVGEIAAACAAGVFSLADGMRLICERGRLMHAAPGAGGMALV
RASADEVEALLVPEVEIAAINGADYTVLSGPQDSLAGVLARCEEEFFYVKPLHTSHAFHS
AFMEPVLAPLRAFADREVEFSAPALAFVSCTHGRLFAPGEVPDAAYWSRHARAPTLFHAG
VEALLDTGITTFLEVGPHFVLGDLGKRSAKALGRGEGLAWLSSARRDDDGWTALLDAMAQ
LFVRGVEIDWSAVAVAAGERPRRLHLPTYPFQRQRAWIPAEGLRPFRPAE
>A0A0H3J6A9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Clostridium pasteurianum DSM 525 = ATCC 6013|TrEMBL
MSKKENIKDDVKLSILKGKPIENIYYNKGNLANLLIEAAKSKINNGIVFVEEDGREVYLS
YKDILDKAYNALGILQRLGIKKGEYAIFVIDESIDFVVNFWGCILGGIIPVPLTHPTVFT
RGNAVSEKIAAIWKQLKEPVLIIDGKMKENYNSFKKSFDLKSMKIINTDETKTGDKKGTI
NLGEVNSPAFIQFSSGSTNTPKGVVLTHENILINVESMVKGVRLCAEDTIVSWMPFSHDM
GLIGFHIAEVAVSAKIINIPTLSFIKNPILWMDLISKHKGTVTCSPSFGYKLLLSRMKEE
NLKFWNLTSLRLIINGAEPISTSLVKIFLDKLSVCGLRRSSMIQAYGMAEASLTITLSPL
DKDPMHHNLSRKIMGIELKAVINKSDNSDSILIADLGYVVDGMELRIINFTGEIVPEKII
GEIQIKGRNITPGYLNNSELNSEVFNNGWFSTGDMGFVVNNRLSITGRMKDIIFVNGQNF
YAHDLENRIESLEEVEPGKIAICAWQDEKEKSEKVALFSGLSGEAEFHCKIIAFVNEIMG
MNIDYLVLVKDIPKTASGKIKRFALLENFKNEQYTDSTYTAKELLINENLNDRNKNKILE
KEGIEQDTYLNIIRNIWGKVLEINPESIPFNRPFLTLGGNSIKAIQLLNYLEEEFSITLS
HDILIKCSTINEMKEYLLNFINSNNSENLLKEDEKREITLKKYNRLESEDIAVISLACRF
PEAKNPEEFWNNLEKGKNSISEIPYDRWNIDKYYDKDKKHGKTYCKTGGFIDNPYAFDDE
FFNISSEEAEIMDPQQRIMLELVYEVFENAGYSKESVNSRNIGIFVGTGINNYFEYHLNT
LNMNNIREFTSFNSFSEYEKKSFMEEWENNFGYTKEHPNLLVDNILNMVAARASQEFNLK
GPSLTVDTACSSALVTIHMACDALRKSECEMAVAGGINLLLTPTPYIYFSSAGALSKTGE
SKVFDSGADGFVPGEGGGLVLLKPLSRAIDDKDEILAVIKGSAVNNDGHSIGVMAPNPDG
QKRVIEALYKRENIDPREIQYVEAHGTGTKIGDSSEVRAIAQAFNEWKLENQSIAIGSVK
ANIGHLLNAAGIASFIKVVLALKNKIIPPNVNLNEPNPMIKFSETPFYFTQNSKKWKSSE
SGKRRAAINSFGFGGTNCHMLLEGVPEEMKSSSQEEKTISKQVLCLTAHTEKALNDKIWN
LSVFLKQNINYTLEDICYTENMKNASLKYRDSIAANSVKDLIEKLDKHIGIKTPIEKSPK
IALMFTGQGCQYVGMAKELYSFIPKFKKYVDMCSEAFYPYLGEKITDLIYGDEADEKILA
QTNITQPVVFTLDYSLGRFIMELGVKPYCVLGHSIGEWVAACIAGVVELKDAAKIVSTRG
KLMNSLKIPGAMAAVFVTGDKLEALINSFNKEVWIAAYNGNHQVISGVSKSVDEFISILE
KNNIVCKRLKVSQAFHTPLMESILKEFQEEIEGIEFKKPSIPIVSNITAAFIDKPFDTEY
WLKHILSSVKFEQSIKFIRDKGVNTFIEAGPDKTLTSMTKGVLIGEDFNILPTVNRKKDN
WEVFLGTLGNLYSAGVKINWEVFYKNFSYKRIHLPSYPFQRKIYGPKFGNRNLADRWFYR
WHWQEAAEIPEKKIDPGAVIIFSDSKGIGNEISRRFNQERNPIYFVEAGEEFKYEGKNKF
IVNPDKKEDYINIIKNLPHNLSAIIHLWNLPYSDFNEEDLVLSKDKLLQESVYSIFNIAQ
AAKAEREENINLIVVTDRAQLINKRDTILGPHQSIAAVLAQSIDEDNTDITSKIVDIDIN
EYVSAVEAADRLFHEFNSKSDSERISVIRENKSFIRKLDTFKPSIEKVKINSGETYLITG
GTSSLGGDLAKELAKQANINLILTGRTALPKRQYWEEKCSEDIREKINLICDLEKLGAEV
MYVSVDVTDKDKMKDLINAIDNKYGSIQGVIHAAGVLDHSSFKLLNKNTEILKKVFAPKF
QGTIITDLVTRKEPLKFFVMISSVSASKKKWSQGLGEYAAANSYLNAYSNYRNGIGAEGK
TIVVNYSLWDNKGMGAVFGETAGNAVKAQGLKPLSPKKAAQIFIEAISVSGESNVHVMDL
IKESIVKKPENKIIEDIALSTAEEVSYLAVKEVKEIVYKIIGEQLDISVDELDIGMNFLE
LGMDSVGAIKVIEKLSKELKVQLYPTIIFEYQTPETLANHIEKSYFKDVKVTNLEDIQET
EDTKIGDIAIIGMSLRIPGADNLEEYWDILDNGKVTLGQIPEERWSIEEEYNENKDSLNT
SYSKYGGFINKAYDFDPVFFGISPKEAEVMDPQQRVFLEVAFEALQEAGYAGKYRTENVG
VFVGAEQNNYMEHFSNYRNYKILKEKFEKSTWFNNMTYKEKKNIINTLINVLKPSELRAD
AVPGNGLNEIAARVSHCLNLMGPSLVINTACSSSLVALHMACESIKRKESDMAIVGGVNL
NLSSVPFISMSRLSAISPSGECRPFDKDADGMVLSEGVSAIVIKSAKEALEDGDNIYAVI
KGSAINNDGHSQGITAPRPMGQAKAVENAYRNSEINPETISYIEAHGTGTPLGDPIEIQG
LTSAFRLFTDKRKFCGIGSVKSSIGHMLAASGLVSLIKVVLSMKNRKLPATVNYKNPNTN
INFNETPFFIVGGESSVWQPVGENPLRAGVNAFGFGGTNAHIILEEAPVSEQSKLKPNNV
KTHMLQLTGKSETVIENTARRLKLYIELNPQVNLSSICATMNSSQKQMKHRSVFIAESRE
KLLTLLDYAVQGKQQVDIYSGKANPKRGNICYLLLDGSIHINEDEVEILKNRFQIFNRSY
SECEGELKTIQTTKEIDGTVKKRIEAFSLEYALVCIFKDLKIDIESIIAKGFGILSSLVL
TGNLSVKEALNLIVSNFNLDKVYDVDNKRKTYFNCDVITNFEAFKDSEEKLTVIKDVLDE
NRIYKKLNQIVKKNEVIICIDSSESIKEEISELNTEGILLQLCNEVDNKNFEKEILILLA
KLYICGADYNPRNIYPPKVLKVSLPSYPFENCTYKAEFKEDMDRYDEFYNKNIIIEEESY
YDRMTDYKEVLDSSDDSRLIKITGRSELSINEKQISYERLSRDFNFK
>A0A379GDE2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Proteus mirabilis|TrEMBL
MKNVAISGWELNLPSIVNFEQLSEQLLLKRTIKTEKYFSDDYFVEYFKFNHNPAVIPYQN
IPNDHFEILTRLIHNSLKRANITLEKLRASRTIMYLAGHGPRADFMDYQGFYDKNDAEDV
QYSPQIKSLHAASFAQDELANKLWAEYQLDFPPIPIYCASNSALMAVHIGHNEISQDMAD
IVIVLSWNSLLLQDIAFMDSQGMLVEAHAQPLSKYSDGVTLSDGYAVMILESQQQINSRQ
YLAPAYIYHSVFMQSNAERTMGGTLFNFYTISKVISQLLDLSHYLPSDIGAIFIHGNGSI
ISDKAETVAITNIFKQPIPIISYKGQIGYISNCSGIIDLMIIADSLKNNRLIPSTTHYPI
DDGMEVNFLTNQECVNYSAKPILKIGLGMDGSIIAMLLIANGEQG
>A0A653FMA6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium smegmatis|TrEMBL
MTDGTLCDHRVPVVLSAHAEDLIAHDATAILRYLDGRTDTAPSDVAYTLLRTRRLRRHRA
VIRAGGLDELTAGLRALADGDDHPLVTRAAAPQPGSRRRVAFVFPGQGSQWPSMGVEAYR
LDDYRAEVDRCAAAFEAAGAASPLDYLLAHPDSGVSTNDFSQVQIQGAQFVHGVALARVW
RSHGVVPDITVGHSLGEIGAAYVAGAITLPEAVAIVIARATVLDRLTGPYRVAVLGITPE
QAAEVIAETPGWLELSVVNSPSSVAVSGETGAVAAAVRTVAARGAFAKEIEMWFPAHTTA
LDGVRADLDALLPAGRFAETPVQFIGSATADVVTTGTDFADYWYTNLRTTVRFDQAVARA
ARRGARIFVELSAHPALLFNMGELLESTRGVVLVGSGRRDEPLPERLADNVITVALADAG
YRWRDQLGDCHAVLPDFPFAPMRAEHLWAQPDPLPPVTGLTVAAEQWHQVAVPEVSGHHR
IAVVGLDSECAVAGHLRDAAERIEGVEVVAPAAADTLLVVAPMISENDPVLAGEELGRRI
DEGLLRYPDLLTETTRDVWLVTGRGEHVPVDRDGSLPVGAAVAAMHRSIAFEHPDQNFRQ
LDVPMGLDTEAAVTAVAAMVTGTTDLALRCDVADGPGTTLWRRGMRDASAAAAPWPTGVL
DDVVITGGTGAVGLQFARRLAALGARRIVLLSRNGIEGNRVDELPLGVEIVAPRCDLTDI
PRVRDVAAEFGGQGASLIVHAAATATIAAGSALTGAAAQATFTAKLAGIENVLAAWPVRP
DARILLCSSVSGLWGGHGHAAYAAANRLLDVMAERLRSEGRRCTAVRWGLWPGAGIIDAD
EITRVERSGLRAMAPDRAVDTALQDFAGDPLVFSADAQRLALFLGTDADTGTGREATHAA
QHRDAGPPADAEHHDTGAAVRIALAAVLKLADTTGLDLDASLLDLGVDSLLALDLRKKLK
KTTGRSVPLATLLGGVTATELIEHLERPEKETFSRD
>C8XIR2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nakamurella multipartita (strain ATCC 700099 / DSM 44233 / CIP 104796 / JCM 9543 / NBRC 105858 / Y-104)|TrEMBL
MSQPGTTTRPPIAVVGVSALFPGSSDVTGFWRDILAGTDRMTPVPPTHWLVDDYFDADPA
AIDKTYGRRGGFLDPVDLDPIAFGVPPSVVPATDTAQLLALIVAQQVLDDAVRGQFTELD
RSRVSVILGVTSGQELLGAMASRMNRPMWLQGMRRAGVPEDVAQRACEQIADLHPAWAES
TFPGLLGNVVAGRVANRLNLGGTNCVTDAACASSFSAISMGINELYLGDSDLVISGGVDT
MNDILMYMCFSKTPALSRTEDIRPFSDQADGTMLGEGIGMVALKRLADAERDGNRIYCVI
NGVGASSDGRAKSVYAPVPAGQARAIEAAYAKAGYGADTVELVEAHGTGTVAGDAAEFAG
LETVFNATGRADRQWCALGTVKSQIGHTKAAAGAAGLIKTIMALQHRVLPPTAKVQRPNP
KLDLGASPFHLTTRALPWVRDSAHPRRGSVSSFGFGGSNFHIALSEYTGSGNRAPRRRTS
DVELLVFSRADAAAIAAELEQVRQGLENADGPADLARLAWDSQRRFDSGAASRLSVLVTV
TAGAADLRAKLDQAIGLLRRSPAAAFQTPTGIAYGTGAPAGELAFLFPGQGSQYPFMGAD
LAMQFGAAIAAWDAAADACDGPEPLPGLVFPVRTFADDEPVAQRERLTATQWAQPAIAAT
SLSMLRVLDAIGVRADHVAGHSFGEITALHAAGALSAADAVRVARRRGELMAQAAQIPGA
MTAVVAGLDQLRELVDASADVVIANHNSPTQVVLSGPTSAIERVEGELGRLGLTFRRLPV
ATAFHSSVVDGAGAAFTEYLATVDVRPPVAVVHANETAAPYPTEADAVRAQLGRQLTRPV
RFVELIEGMYARGVRTFLEVGPSSVLTGLVDAILGERDHRAIALDNRTKGGLGAFLGGLG
QLAAAGVAIDFAPLWAEYGSPADEPAAVKPGFTIPINGANYGKPYPGDLAELVGPNPDSG
SVPVTPPAPPSVPVAPVPVAPVPAPPPAVPAAAMPAAPPRSEPVVSATPPAVPSPLPSAP
PSPAGGPSDEVLAVYQAVQLQTAQAHTAYLNTVAQAHGAFLQTAQQSLAAVGWLAGAETG
LLPAAPVAAGVAADAPAPVIAAPAVPAPPAPSAAPSAPVPPPAPVVAVPPPTPPAPSVPS
AAPAPASIEVVAGAGPSLAEVTSALVAVVADKTGYPAEMLSLEMELESDLGIDSIKRVQI
LSAMQDRMPQLPVVDASAMARLLTLRQIVDRLAEELGEPAVPVAPGPVEVVAGAGPSLAE
VTSALVAVVAEKTGYPAEMLSLEMELESDLGIDSIKRVQILSAMQDRMPQLPVVDASAMA
RLLTLRQIVDHLAEELGEPVAQAVSAEPARIDQGPGPELGRLVTEAVESSGSGAGALAGL
GGRVAVTDDGGGVGAALVDVLTGHGLDAELVGELTGNGYAGVVFLGGLRALTDVTDAAAV
NTEAFRAARAAGSTSESFVTVSDLGGSFGRDDLDPTRAWTSGLTGLVRTAALEWPATRVQ
AIDIQRAARGPQDVARAIGDELLRGGQEIEVGIRADGTRLTLSSVPARVDGGAMPLGPDD
VIVASGGGRGVTAATMVELARATRARFVLLGRSPLDPEPAVCAGAADDVALKRALLDDAT
AHGRTVTPAELGRQVRAILANREIRQTLEQIEAAGGQARYLAVDVTDADAVAQALQRVRQ
EVGPITGVVHGAGVLADRRIVDKTDAQFDAVFRTKVQGLRSLLAATAADELRLLCVFSSV
AARTGNEGQADYAMANEVLNKVAVAERTRRGPGCIVKSFAWGPWSGGMVDDALAQRFRSM
GVALLPLDVGAAMFVAEIASPQVDQVEVMIGSATLGAPAAASRGA
>A0A2G8XS22|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii COUG|TrEMBL
VKDDIVSAVKEIEARGFPPIRGIFHAAGVTADASLANQTREAIEQVYLPKVTGAWNLHEV
CESMGLDKNLDMFVMFSSVAALLGNFGQANYSAANACLDALAEYRRARGLCAQSIQWGPW
IEQGMAADLKALAEKAGLRGISNELGIRVLVEAVRNSKTVVTFLAQSFIWKRFVQRFDVV
PPFFSNIEFETASPGAFRVLYSSMTPDELHTYVSNVVLDTARQVLGTSELPALDSPLQEL
GIDSLGAVELRNSLSQRLGVKLSATTLFDYPTIRAIIDYIVNQVSGEASAAKATSGALVS
AGLAAGRNSPIAVVGYSCRLPQGSETPDKLWEMLRRAQDCVVEVPLTRFDVDMFYDSDID
AKGKMYVRKACFMDDADMFDNSFFNISAAEVTYMDPQQRVMLEVAYDAFYSAAYSREHLI
GKNYGVWIGCCNSDWHFLEQQSNPDKSSSYSGPGGSGCLVSNRLSYVFGLKGPSMTIDTA
CSSSLVAADCGAQAMRFGYCDGALIGGVNLMLSPQLFLAFCKARMLSPDCRCATFDEKAN
GYVRGEGAGAIMLRHLADAQREGKRILGIVRGTAVNHDGRSASLTAPNGPAQQDVIRSAL
QIGGVDPLDVALVESHGTGTALGDPIEMGAIKAVYGAGRSADSPLVVGALKSYIGHLEGS
SGIAGILKVLLCLRHHEVPPNLHFDTPNPHMDLSDFHVVLPKKQMKLQPAQKSSTILGSV
SSFGFGGANAHVVFEEYPEPTMATDVGGERRSTEAAESAGKKRLAFLFTGQGSQYPNMCK
QLYEEEPVFRSHMDACFTVLEGKLDVKLRDVIYPTAENDVEMLNLLNQTGYSQPAIFCVE
YALAQLMISKGFSPSVVMGHSLGEYAAAAIAGVMDWKDALLLVHERASIMQHIDPNDGVM
YACRASEQDAQAAVEKALGEKAVAVTVSAINGPRSIVLAGTQPDVLAVLKAMDMQSRAKQ
LTVSHAFHCPLVGEAAALLLPKVESVKLSNPNEGITFISTVTGKAVGAGELTKPEYWATH
ITKPVQFLQGMRAAVTSGEAGIFIEIGPRPTLVNMGQQCVPRNDYTWVAPVDPKDSNRNS
FPQALEKITSNMVCTYTWKRHAFPWTVVVHPFVDKFVPDQDETKATSQKLLTPAVGELLH
DHVVNGTAMMPGVGFLEAMAAGGFMMLDGKLPSTVVALRDCEFERPMLIPKIDPSTGEFT
QAAKLMITVNNKDITLKSIMDGEEEEIFHSRCTFSLCPATSLPTEPADLLTSLQGRITTP
VPITTLYETLQSVGLQYGARFQSIRECYAAASDEVLAKLRPKLPLHSFERNFRIHPVLLD
GALQTAAVLFAEMGHKRPLVPVGVKRALLARVPAGSEVWSHVVVKSKDLRSATMDVTLFS
TKGTILGQLVDVAVRAFDAVAGAQIPKGLLWEVSWVPKAKAPVEDGVDTVENEASETITP
TAKLAVKPTGKVEGLARQTAVNGQPKWLLLKTPSSMLEGLQKALQGTPSAFVKELDEKHP
NNAISSKIHNSEWDAIIYLGALSAAASSTTCVADALLLANTLGNTAAEKPLPNVLFVTQG
QHFIRECGDVPTTAVPTQTGLYGFCRSAQLELENIIGRPVYLGTLDFAAKDPTLDDPAAF
VSALQRVLAEADPTGAAGTCEPHTVIRGGKEMVPRLVKSSIECRGAVELHMSDRGALSML
KLRPMPKSARVPPPRDCVEIRVRAVGLNFRDVLNVMGLYPGDPGPPGADCAGTVVAVGEG
VEHLRVGDAVFGIAQGALKTFVTTSAHLVRPLPGRLTFEQAAALPVVASTVEYALHDVAK
VKKGDKVLIHAVTGGVGLAAVQFCKRVGAEIYGTCSGGKKEEFARSVGVKYITSSRDPKK
FAEDMCEFLGNGKHKIDVVLNCLIENYIPETLKFLAPNGRFVELGKRGIWTREQMGTVRP
DVLYETVAIDTMMEEDPVWFGGMLDRIRNLVDGSMLQPLPLHTFEMTDSSEGGVAAFRFL
QRAQHIGKVVIRLSSALEVKNFTTNSRQETENEDSGERHTLSPATAVGKPLSQSVADQMR
KTYIITGGTGGLGLVVAQWLIEEGAHNIVLLSRRGEPPSSVKAGDPVWKYLCGEEQPNCI
SVTTLKCDVSQKDDLLRVFKEIESRGLPPVAGIFHAAGVTADAALASQTADSVDQVYLPK
AIGAWNLHDACEALGLNKSLEVFMMFSSVAALLGNFGQANYSAANACLDALAMYRQSLGL
CGQSIQWGPWIEQGMAAQLTQHLEKVGMRGITNELGLRVLGDVMMHPTVAVVGAQSLQWR
KFLRRYAFEMPSFFSLVPMAGAGSSEASVNLATITKEDLCELISSLAQAVSGAAEKPAVD
TPLMDLGLDSLGAVEFRNSVADKVGVKLPQNLMFENPSISSISDYILDKAAGKHGESGVT
GTNGGSGEGSDIPALDTPLDQWLMSVLEPAERFALYIDSFASEYGTLQKMAAEEDIITAL
EDLGVEDGGDFERLHVAWDDLCNQINTAKRMAAKDIRPSSTAVSVSDHPKPRMPHPMEDV
DTLLASLDFDVSTLRPATAPDKVKNVLLTGVTGFVGRVQLASLMQLKQRPDLRVYCLVRA
RNADHALSRIREATKEAKCWQETFVSRIVPVTGDFTQPLLGLSSEEFQELARKIDIVYHT
GGDVNLLSNYGRLRATNVLSVKAIIDLCTTYKVKPLHFASTLGQFPAFFAMFTGHFSGES
IREDSTPDVSQMENFYPPSRQGYPWSKWAAERVLEGARKRGLPVAIYRLPNTYVAYKTGY
TNKTDYATALMIASIQEGVFPIGAATAPLTPVDTICDMLVEASFLEKPKHWVYHLFDPRL
VTRADLEQWSQELGISYVGVKVDEFLEAIKKRGPESPVFKFVPLMQHWRRFWFDPEERTE
SFPISNEHIFEDLPHMRWPSLREVFKNSLLYSVRMGFFPKNSKSIILDPQVALNEARRIC
GLQLMGREGEDFFLHPWRVLQESARRECDLLFGGQLAVYRTVRHYFMNVMYLADAQAKCP
EIEKQEIQAPLIIVGLNRTGTTFLQNLMSTDPSNRSLRYCEMIAPYGPDGNYRPKGLPNT
EESWKKDPRIPFAQEILDSQLGLSEEWMAIHTQRAELPEEDFVIFEHCGRCYSICTEFSV
PSYREWLASDNYKETRKAYSFHKRFLQHLQWQRPAKRWLLKMPFHLFTLEALFETYPDAK
IIFMHRDPKETMGSWASLVKHAQQSLMDNVDPSALGREELRAMSTMINRALAFRRSHPEL
GPRFLDVQYQDLVNNPIGVVKSIYKHFGIPLTLAAQTGIASFCNENRKHRDKLTKHMYSL
KDVDLTDGMVQEAFKEYYDSGLCKYLSSAR
>D8G899|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Kamptonema sp. PCC 6506|TrEMBL
MEAVENVGVGNELDIAVIGMSGRFPGAKNIDEFWQNLQDGVESISFFSEAELEAAGVDAA
TASDPNYVKVAPVLDDVDLFDASFFGYSPKEAEMLDPQNRLFMESAWEALETSGYNPKNY
SGSIGVYASQSLSTYLLRNVYPNLDFRSSILSSRNVQALIANERDFLPTRVSYKFNLKGP
SLNVQTACSSSLVAIHLARQSLLMGECDIALVGGVSIYLPQNAGYLYEEGMMHSPDGHCR
AFDAKSKGTVFSGGVGVVILKLLANAIADGDCIHAVVKGSAINNDGGFKIGYTAPSSQGQ
AEAIAEAIINSGVDAETITYVEAHGTGTLQGDPIEVTGLTKAFSHYTEKKGFCAIGSVKP
NIGHTDVAAGVTSFIKTALMLKHKLLVPTINFEEPNPQIDFANSPFYVNTKQQPWTTENG
IPRRAGVSAFGIGGTNAHVILEEPPEVASIPSETERPLHLLCLSAKTEKALNELVAKYET
HLEISPNQPLADICFTANAGRSHHNYRIGIVADSAQDLREQLADFSAGEDFSEVITKCSN
TNPPKIAFLFTGQGSQYIGMGRELYDTQPTFRQTLDRCDRLLKPYLEVPLLDVLYPKKGV
YSPLNETAYTQPALFAFEYALAQLWLSWGIKPDAVIGHSLGEYVAACIAGVFSLEDAIKL
VAERGRLMQALPPNGEMVAILANAELVKAAIAPYQPNVVISAINSPEETVISGTSEAISA
VLSDLQPQKLWTHKLTVSHAFHSPLMAPILNDFSQIAAQITYAEPQIELISTVTGESAQV
TDMGCAEYWCNQILQPVNFESGINTLSALQIDIFLEIGAHSPLIQMGRRCLPETTAVWLS
SLHKERSNWQQLLASLKALYVHGADVDWAAFDQDYSRRRVLLPTYPFQRQRYWIEPAARV
IVSEQQTSLAPVHSIFEEADLALSTAGLNSQKVTWRDRILTAKNSDRPSLLESYLCQQVV
RGLGVKRSEVCLEASLRELGFDSLMVVELKNQIEKDLEISLLVKELIAGPSITQLALKMS
SQLTPAIEELLPTLEIAALTVPQDTNLSWINKSEFSTSAKIRLFCFPYAGGGASTYRSWE
SQLPPEIEVCPIQLPGRENRISEAPFTEFTELVEVLADVLKPMLDRPFAFYGHSMGGLLA
FEVAKSLRNRFGLLPIHLFIGATIAPQLPNPFPALDLTSPLNLTRFLRSLGTSSKVLQNT
ELMEALLPTMKADFLALESYTYKDNAPLDCPISAFAGSKDRFVSQEDMAAWSIQTLSRFH
LESVAGSHLFLESDREQVLQTICRELAPNSLLHHQVSPFSRSLTSSGVNSHK
>K0K3V4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Saccharothrix espanaensis (strain ATCC 51144 / DSM 44229 / JCM 9112 / NBRC 15066 / NRRL 15764)|TrEMBL
MGSERIAIVGIGLRYPDAGSAGELWESVLAGRRAFRRLPDERMNHADYFSPDPAAPDRFY
AAKAAVLRDFEFDRVRYRVAGSTYRSTDLTHWLALDVAAHALADAGFPEGEGLPRRTTGV
VLGNSLTGEFSRANVLRLRWPYVRRTVAAALTAKGWPEDETAGFLHDLEVQYKAPFPAID
EDSLAGGLSNTIAGRICNYFDLGGGGYTVDGACSSSLLSVATAAKSLADGELDVAVAGGV
DLSIDPFEVIGFAKTGALSTGEMKVYDRDSNGFWPGEGAGALVLMRAGDAAERGLDAYAT
IAGWGVSSDGKGGITRPEASGHRLAITRAYARAGYGVESVSYFEGHGTGTALGDATEIEA
LSSARREADPAARPAALSSVKGNFGHTKAAAGVAGLIKAALAVHHQVIPPGTGHHDPHPS
LTADDAVLHVPRDAQLWPADRPVRAGVSAMGFGGINTHITLEQAAGTARRTELGDRTRAL
VTGRQDAELLLFDGADVAEVRARLAEVAALVPKLAFAELADLAGVLAGRLTGGRVRAAVV
ARNPEEAARRLTRLLDGAGPVTDPADGIFLADRAEPPRIAFLFPGQGSGRGAVGAIRRRF
AAAEAVFAGSGLPTGGDQVATEVAQPRIVAGALAGLEVLRELGIEAGTAVGHSLGELTAV
HWAGALGADRVLELAAERGRVMASASRGGGAMAGLATGPERALELAGDEDVVIAGYNGPA
QTVLSGPAEAVDRVCAAAKAAGVHATRITVSHAFHSALVEPAAAAMGERLADYDFDRPTR
PVHSTVTGDLLDPGTDLRRLLRDQVLEPVRFHAAAARAAADADLLLEVGPGRVLTGLVAD
IAPGTPAVALDTDHASLAPLLTAVGAAFALGAPVRVSTLFAGRGLRDLPLDGAMTFLASP
CETAPALDVALVADAPAAADAVTTSEGESTLDLLRRLAAERAELPLDAIGPDTHPLDDLH
LSSITVGQLVNGVTSSLGRPALTATPNFATVRLGELAGLIDELASTAHEQERPGEVPGVA
PWVRPFAVTHVPRPRPDAEPAGPGEWTVFARPDHPLTAPLRAALPGDGVLLLPEEGDPGL
FLAAARAVLAAPHGTRFVVVQGRLGASGLARTLHLEAPHVPVTVVDGEPGVEDVVAEVAA
TTGFTQVRYAGGVRTVPVLRAVTGQASGTALDAEDVLLVTGGGKGITAECALVVAQDSGA
ALALLGRADPADDAELSANLERMTAAGIRFRYERADVTSPERIAEAVARFREELGEITAV
LHGAGRNEPRALTGLTDDEFTATLAPKVEGLRTVLAAVDPDRIKLLVTFGSIIGRAGLRG
EAHYATANDWMSELTVEFGREHPSARVLALEWSVWSGAGMGERLGVVEALVRDGITPIST
DEGVAVLREVLADPGLGPVLVVGGRAAGLPTLEFDRPDLPLTRFADRVLVHYPAVELVTE
ADLSAGGDPYLADHRLAGDLLFPAVLGMEAMAQVACALTGNAAPPVLEDLEFPRPIVVRP
DGALTVRIAAQVRAPGVVDVVIRAEDTGFGADHFRARLVFPRPELTGAPLEDPGLPPVPV
DPVGELYGGVLFQGKRFQRLLGYRRASARHAVAEVAATPVSSWFAPYLPQDRVLADPGTR
DVMMHAIQCCVPDATLLPQRVARLILADPADRSAEYVVLDARERSQEGDSYTYDVDVRDP
SGKLVERWEGLVLRAVHKRDGAGPWTPTMLGPYLERSLERVLDGAGAVVVEPDHAETDLA
DTAPDRRAQTALALSRALDRRVDVRYRPDGKPEVDGAAVSASHGAGLTLAVAGTGRLGCD
VESAAPRTDADWAGLLGADLLPVRDLLRTEADESPDVTGTRLWGALECLRKTGSTSRALT
VDRVHPDGWAVLSAGDAKVATWATTVTGRPDPVVFAVLVGKED
>A0A7G6UWH9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Burkholderia cenocepacia|TrEMBL
MNSKIAIIGVACRFPGSANNLGDFWQLLRDERDAVTEIPADRFGTDFYQHPSKREPGKSY
TFAAGVLDNVAGFDAAFFGISPREAAQMDPQQRLLLELAWEAFEDAGVRPADMRGSNCGV
FVGAASMDYGNRNMDDLNVIDPYSATGNTLSIASNRVSYLFDLHGPSMTVDTACSSSLVA
LHQAVKALQSGEADVALAGGVNLLLHPFGFVSFSKASMLSPRGRCRAFDATGDGYVRSEG
GAFVLLKPLDRALADGDTIHAVIAGSGVNSVGHSPGGISVPGAAAQASLLRSVYARAGID
PRSLAYLEAHGTGTAVGDPIEARALIDVVSGERPADRPLLIGSVKTNIGHLETASGMAGL
LKAVLCLKHRAVPRSLHFVTPNPGIDFDGGRLRVVDRYMPLDAGDAPLTVGVNSFGFGGT
NAHVVLTEAPVANDVSPAAPEPTRAQPSPLALTARSANALAALAGRYLAMLDDGGDWQAL
AAAAARRRQWLEHRAIVAPADVAEGRAALAALAQPAQDGLPACVAAGQAPADALRTALVF
SGNGCQWVGMGNELYAENAVFRAALDEVDALWRADGSPPLVDVMRGGPGTTWLAGAGAEW
LAATENAQPLLFAIQVGMIRVIDARGMRYDAAIGHSVGEIAAAWVTGALSLADAVRVIKI
RSRAQAMTRGSGRMAAVGIGEAAARELIARHGLARRVEVAGINSPDAVTLAGELQGLQAL
EAALRGSGKFFQMLDLDYAFHSSHMDRIEPVVLAELASLRPQPGNGRFVSTVTGGALAGN
ALDARYWWRNIREPVRFGDGIAYLIEQGVRLFIEVSPHSILRTYVKQALTAAGVTGAVLP
TLKRDHGSAATLRQAILAAIAHGASVDPDRFAPGESRAALPSYPWQRDRFWLTPTVEGYG
LVNRRREHPLLGYRLHEHAFGWENQLDPAKLPMLADHVVDGGVAFPGPATWKWRSPRRAP
SSIRRMRRSKTSRSARRSCSSRSRRSCSGS
>A0A7D3VQ12|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinomadura verrucosospora|TrEMBL
MEDKRMIEGWPDLLAGAPPVLPIVPAPLNAPRRTEPLVRAVPLAERTARALAGGAADEAV
AIAVAALGVLVLRYIGQTDVLVRLLGDRPAVARLRLGGGPTAERTRRIAAEAIGEAARLP
PLGDAELLRIVPREPGAAACHAAVAMHAPGRGRPGRGELRCADLALVLRPVRERLRAALI
VNAARHDPSAADRLAAHLGRVMNALTTPPPGVRMDRLPLLDDAERAQVMLGWNDTAEPVP
GPHLPDLVAATARERPAAVAVVHGTRRIRYGALDADADRLAQHLLSLGVRPGDVVGVWMP
RCPEHIVAQLAVWRTGATVLLLDPQRDAGRLAYLLADSPLAALLTVTAAGPRPGAVLADR
TVVLDADPAWRRAPARSPGHRLRDTDVCHIAYTAGSAGSPKAVLMRHGSLRNTVHVLRSE
CAITGEARGTWLSAPSLSLIQADVLPLLAAGAAVHIPSADAAGSVTALREWLLLAGITHV
LVGRERAKALWSMSWPPNCALRSMRVIGGQVPAWPPPGLPFSVLNVYGSAETNVVATCDL
TTTAAALGDAVRAQRRPPIGRPVANSRAYVLGEDGEPVPPGVLGELHVSGAGLARGYLGQ
PDATAARFRANPFPEDPYAVLYRTGDLARYWPSGVIEVVGRLAGPRAGAVRRADGDLLGG
TVIRRIAALYGAVLGTGPVGERADFFALGGDDERAGRLLRALYDELGTTMTIAELRAAPT
VAAVAYRVVRAWLGGTPPTIVPDAGALRSPFPLTPAQRRLWLAAGGRAGPLDLYEWPMER
PDPGRLDRAWRTVTVRHAALRTTVGEDGRQVVSEGPRPLETVDLSALDPAEARARAAAGP
ARLRSTGEAPRLRLTLLPGGTAVAALLVPPLLADDDSVHRVLLPELAAAWHGRPLPPPPA
ITFRDYARDSLTRWAQHELDSAAPAEPRVRGGEPRPLRRELPPDVVARLRARCAEAATGL
PDALVATLHDLLAETDLSWLTPGPHTLVQRTAHRVPADPAVGGLVGCFSVWRRIRLAEGN
PTFAERSRAVAHCPTEAAPLRCAVQVSVPVDRPGPVTAATILSRGPLADADLRLVPDRDA
LRMHWSFPADADPAAAAALADAYAARLVRHAEDEAVWWEGVDAFNKAHGT
>A0A1X2E005|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacter terrae|TrEMBL
MSGPDETVHTLRTLVDLLAQRARERGDKPAFTFSRDGDEHETSQVTYRELDLRARQIATD
LQRQGASGQRVLVLCPPGLDFIASFFGCLYAGAIAIPVHPPMREHLIGRVESIIGDVQPG
FALTTAEIEPRIKPAIDGLPGGQALQWSITDSYPPGSEAAWVAPQIDGDSVAMLQYTSGS
TSAPKGVVLTHGNLVHNLLTIAEAWNPPHHSEITGVFWLPPYHDMGLIGGLLETLYVGGT
SVLMPPTAFIKRPMRWLEAISRHRATITAAPNFAFDMCVELSSPQERAALDLSNWTVALC
GAEPVRTATLEGFAEAFAPAGFRAESFYPVYGLAEGTLLVSGGSDSPLPLVQNVDRVALG
DNRVVAVSADDPNVATLVGCGKPRGGQRVIIVDPDTRRECAADRVGEIWVAGGSVAHGYW
GAPELSAETFAATLSDSGEGPFLRTGDLGFIHSGELFVTGRRKDLIIIRGTNHYPNDIEL
TVQNTNPGLLRGRGAVFSIAPEPGAAEQLVVVQEVDPSRLSGAAADEAMQVIRTAITENH
SVRTHSVVLVQPLQLPTTSSGKIQRSACKQRYLDGELPVVAVWPPAAPEPTEPPAQAEPE
PAPTVAAGSGKRGAAEISAWLVDRLSGELELPAAEIDPAKPFAFYGLDSIHAVRLSTALE
QWLGCELAPTIAYEYPSIDILSQHLARSKTLAAETPAAGPAGERPERPAADEPIAIVGIG
CRFPGADGPEAFWRLLSGGVDATSEVPADRWDVDAFYNPDPSVPGTAVTRRGGFLGQVDQ
FDFQFFGISPRESAQMDPQQRLLLEVAWEALEDAGQVPDALAGSRTGVFVGISTNDYGFL
RLGQPQLVDAYTGTGNALSIAANRLSYTFDFHGPSLSVDTACSSSLVAVDLACRSLRDGE
CSMALAAGVNVILSPALAINFSKARVMAPDGRCKTFDADADGYVRGEGAGVVVLKPLSRA
LEDNDPIYAVIRGSATNSDGRTNGLIAPSGRAQEGVLTEAFRRAGLPAGAVQYVEAHGTG
TSIGDAIEANALGTVLAEGRPQGSRCLVGSVKTNIGHLEAAAGVAGLIKVALALQHRQIP
ASLNYTEPNPHIGFDRLPLEVVQTLTPWPAGSRAIAGVSSFGFGGTNAHVVLTEAPQVRG
GHPDDTAAPRAELLALSARSPEALTALVGEYEMALFSSGLGGGRALTDLCYTAGARRGHH
DYRLAVVGDSPAALFESLSAYRQGESRPGLSVGHCSAGRAVGSRGVTFIFSGQGSQWHGM
AQRLQADEPVFADALAACDNALHPHLGHSILKELAKPQERSKLTDIGILQPTIFAIQVAL
AALWRSWGVEPAAVVGHSLGEVAAAHVAGALSLEDAARVICARARMLRGVRGRGAMMVTE
TTLAEAQELIAGHEREVAVAASNSHRSTVLAGERKVLEELMAKLTRRDRFCRWIEVDVAS
HSPQMEALGAGLRGSLVKLKPTAPTVPMYSTVTGELVGEKLLDADYWVANLCSPVRFSPA
LRRLLETGHDTFVELSPHPILLTAAREDVEDLRRSCTLLPSMRRDDDGRSTMLGSLGALY
TLGQPVAWEQIYPEGSRCVPAPTYPWQRVHSWLDAGSIAAPRHNGAVVPGGGWRGPIRSA
TQPGTVLTEIDVTTGALSAEQLGELAGQAVEVAFGPGNRSVGALNLNGGPVAAHTVQFAL
ADDAFECYGSTAGAEWSLLATGSIVAGRSGVPAITTAPADPADRSYRVRWQPASLPIDGG
GRSEGRPAEPGSWLILSDGSVADTLRDHLEAQAQSCVLVEPVVGLAEIERVSADSYRLDP
GRPEHFGELLRAAFGGDRPPCRGVVHLWNLLDASPANTGIESLETATTVGTLSVVHLIQA
LTLAGWPESPRLWLVTRGAQPAGDNGSAGLSVGQAPVWGLGRSIDHEHPEFRATGVDLSA
DGGPEELRGLFGEIWSDDRETDVALRGHRRYVARLEPYRETSGQPGAFTLGDQATYLVTG
GLGAVGGEVAGWLLERGARHLVLMGRGAPSATAEATLAALRAAGAQVTVARGDVTKADDV
AAVLATIAATMPPLRGVVHAAGTVDDAILARLDAAKLREVMAPKVQGAWNLHTLTAGAEL
DFFVLFSSAASVLGSPGAANYGAANAFLDALAWHRRASGQPALSVNFGPWAGLGMFTNSE
LHRHFSHYGVEGMPAQDYFAALTALLAGSGELAPQVMVLDIDWALWRPSAQSPLLRDLQV
PGGPQDAAIGSGLFETVQAADPQERRRLLETYLRDLVAGKLGLAPAGLDIAAPLNSLGVD
SLITLELRIQVERELGIVVPVARLLDGPSVASLSAWLGEQLDSRAGAAGPAAPEPAVSPE
TTAQETELLSQVSDLSDDAVDALLQKMLADGEHAKDGG
>A0A0H5P0F7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia farcinica|TrEMBL
MGCRLPGVGHLDDLRRPPGTDVPVAGVDVFDSEWFGLTAPQAAVLDPRLRLALEVVVEAI
DDAGIGYRLRGSDAAVVVAVRPGRDQPESGRADSAPAQGISRLFELYGPSSPVVTDRGEC
AVESGIRLLVDRAVPWVIVVGVDVEPDDAVDGAVAQRDPVAAGESRRAGCAVLVLQRVAD
ARRAGSRVHAVLEIDDGRSVGEAAVGSDPLPAARSVMRVLRAIVSMESETRALDHGATAT
STGAAQPLLPNEIRSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSEEGTGWGGKGT
RVPGSRITVLRNAAQALPRSIDPPVVIAVSGRDRRELGTTALRLAHHLRYAAPHDRARGD
RLALHELACATTRQLPLALRAAVLAADLGEADARLRALAAGATGAGIVAPRPRHRGGLLF
VFAGPSEPGPRLGRAPAARFPAYAEAVAAIADAIRSAGGPRIWTARFGFRVAPDSGWAGP
AFAHLATFAHQVAVARLLEAWDVQPSGVCGYGAGEIAAAAVSGALTTADAARVAVEYSRT
VAHRVPRHIDTEPTPPQWENLDRSGAAQTHPWSSALLLASIDEAARLVAPLRHTVTIAAA
RGPQSVVISGYPPDVDTVVRRAMRRGLRARALGRDHPADPVAGAELAGHLAGLTPRTPRI
PFYSTVRRGGLLAGAATDAAYWGANLGDAVHLDAALVRAIDAGASSVLTIGPSTELAAAV
EGFEQFASSTYTTGGDDEAAALLHALAALHAEGRRVDWARQGPFTVPPPRRRWRHTAVGS
PLPAVIAGAEPDFDHPGVIDHLYGGRPAVPVGYWVSALLHLARRHAASEMLTDLALGRLV
APDDLRQARFRDDGPGGFRVTVPDGTAADGTGPDGTVAVARPVPGPTPADIVDWMRLVDD
GRTARRRLRPLGPGAYYTSLRRHRVEYGPRFPIPERIETGGGRTFGVLSTDGEASIAVEQ
CLHLVVAAARDMLTGKLVPEVSAIGTVWLAPDGGAAVEAHATVRERAPHALTGDVVGTDR
DGVPLLALRDVRIRFREGDDAATVRPAESAPFRTQVWLPVTPAPGAGHGEPARLLVVGDS
ATAARLARATDRTIRTDLCATPEPAAPDHHAGHTAAVLVWPHGTDATAAAAAHHALDVLR
RLRERCRGQLTLVLPRPALRGGADAESAWAAAALARTLRAETGTPVRVVWADDDPPTLAR
LADLLTGRHILDDPELRIGADGVTARRLRAVPADPLPAPRIDPGGTYVVTGGLGRLGAVA
VRWLLDAGARDVVVLTRAPRPVPAPLDGLEDRFVVVRCDVADRAELAAALGDIREDGATI
RGLVHAAEVFETAAFAEVTAGQLTRLFEPKVTAARHLLALTAHDPTDFVLLFTSAAGTLG
APGRAAYAAASAAADALAGGRRRVLALGWEIRRQPGGEPADLDGAAVRRGAELLGAALRH
RVPHLLIGSGEIE
>A0A449GPV0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia farcinica|TrEMBL
MQDDVTAVDPIAVVGMACRFPGNIDSPESLWRFVIDGKHTSSKFPADRSMTELADIAAPE
VVAAMAPMGGFIDEPGEFDPEFFGISPREAKAMDPQQRIVLELTWQALEDARIDPNALHG
SDTGVYVGAMSGDYAYLIPGQKDLDPGYVATGVSQSVLSGRISYVLGLQGPTMSIDTACS
SSLVAMHLAARALKAGECSLALAAGVSIMSTLTGFYALGQHGAISKEGRSKPYSADADGF
CMSEGAAVLVLERLSDARRHGHQVFALLRGAAVNQDGATKGLTVPSAQAQRKVIEAALAD
AGLGPGDVDVVEGHGTGTPVGDPVELEALFATYGSARPAGSPVRLGSVKGNFGHTQAAAG
LAGVIKMIEAMRHETVPPSLGVSEPTGAVDWSSGAVRVVTEASPWPAGARPRRAGVSSFG
ISGTNAHVIVEEPPRTSPAPSEPPRVAPPVLLWPVSAKTPAALAAQAAALAEHVTAHPGY
ADQDIAYSLTATRATFDHRAVAVGGNRAELLDALAAITAGRPVGPIRGQAMPDRGVVFVF
PGQGGQYRGMAKQLIAESPEFAAGIRECDAAFAEFVDFSVFDVLTEAAGAPTLDHIDVLQ
PALFSTMVSLARLWRALGVAPAAVIGHSQGEVAAAYVAGALSLADAARVVALRSRALRTL
AGTGTMASISTSAARVRELLVEVPELDVAAVNSPTTTVVAGAPEAVERMLAVCEREGLRA
RRIHVEVASHTGAMETVAEEIRAALAPITPRPSAIEFFSTVTGDVLETENLGADYWFANL
RQTVNFEDGFQAAFQSGYNAFLEMSATPVLTAAMHESLDQFGAFADSCLIVGTLEREDAG
LRRFLTSVATAHVHGVSPRWSRLYDPATHTAVPLPTYPFQRQTYWLASVHNANGGKPSGL
GLADPGHPLLGAMTELPGADRFQFSTRLAVATHGWLCDHALHGNVLVPGAMLLELALHAG
DRVGCPGVEKLTMYTPVTLPEQGAVHLHLVVGEAKAPGRRSIAIYSRPENEDAPAGQNLW
SLHADGTLTTRSYAEDADQHGVELWPPVGAQQALEPERAYQTLAALGYHYGPIFQGMRAV
WRRGEDIFAEVALPESVADADKYGLHPALLDAAMQSVAAVASMMPTEPGAIRLPFAWERV
QLHAIGAKALRAKLTPAGPDRVRWVLADHNGRPVAVGTLQVRSISMGALAQRGLSGRQDS
LFGVDWPALPVQRTRWTARPGEWAVLGDLPPGLTAGAELTVYPDRAALSAALADGAPVPK
VVLATRTAAGRRAESGPSESGPGATPPTEAVRAELAATLAWLQNWLADERFTETRLVLMS
TGVQAVEPAETVTDLSGATVWGLVRSAQSEYQDRILQLDLDGAGVTLDQLATAVALDEPE
LALRRGTFHGRRIRSGLDAAATAGARLAGHWRLDIPGTGNLDDVTLVTGTAPAAELAPGT
VRVALRAAGLSFPVALTGLAAVAGAPRRLVHEAAGVVRAVAADVTGFAPGDAVFGLVDEI
ADTVDADAALLAPVPAGWSMPQAAAAPVAYVTALHALREAAATTGERVLVHCATGGVGTA
AVHLATHLGLEVFATASERKRDTLRGMGLAEDHLADSRSAEFATRFAGRGIDIVLDLLPA
ELTDASLGLLGATGRFVDLARGAVRDPRAVREACGVTYRTFELGDLDRDTLAGLLAEIAR
LAAAGTVPALPSTRFDIRQADAALRHLGEARHVGKIVLTWPPAFDPDRTVLVTGGTGTIG
AIVARHLVHAYGARHLLLTSRSGPAAEGIDDLVAELTDAGARVRVAACDAADRAALAAVL
DTVPAAHPLGGVVHLAAALADATFAQLTPDHLGAVLGAKADGAWHLHELTRDLDLSMFVL
FSSAAGTFGAPGQANYAAANVFLDALARRRYHDGLAATSMAWGWWAEDTSNTGALDDKDR
ARLTRMGVTPIETEQALALFDAALHTGRPYLVPVGMDLSLLRVASSVAELPPFFRALLHS
RPRATQQMGDSSQLAKRLAGLSPAEQHAVVVDMLETPIAMVLGYSSPEAVHPDREFTEMG
IDSLSSIELGTHLRAITGVKLANSVIFQYPTVNLLAGHVLDQVTPQDAELADPIVSEVEM
LLDRLAALHDDGQVPEPLLERLTGSIGRLRGGEVAVVDGARP
>A0A4R8R9B7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides franklinii|TrEMBL
MLFRTRVARRYRALATVVDHDQLVTALRAVVTDVEHPLVVRNTEPATTRRHGFVFPGQGG
QRPGMGRLFYDAFPDFRTEVDRCAEQFERQFGRSPLSYLLDESLTNDDSARVVQPALFTQ
MTGLAALWRSVGVTPDAAIGHSQGEIAAAYVAGIMSLADAVTVVGTRAGIADEFPADDYA
MAVIAADRDTCEELLARQSGWAELSVINSPSMVGISGQHATVHQIVERLTEDGVFARVIP
VRYPAHTSMIASIGTEIRKALVGHLGAGEFAASDIDCIGATLGSAINCDLPVDQYWFWNL
RNVVRFDRAIATAAAAHIDTFVELAAHPTLQLAIRENLAALGSERTACVVGTSNRNATDL
SEFTANLANLAVHDLGYNWDALRTETSPAVSLPLRDFPNVQNNDIALWLSYRSAGAVSAP
NQPATAPKPEPAPDNIDSRAYPRLLREAWTKVTRRSMMPPRSYAFIDATGEAGPLVDALR
DGAPDFGSSAQIVTDPRESGTGDGDTVVIVLPTSAQHGDHEASDAVAQFFGNRTWWPELS
SSVTGCWLVTVGGEQVIADDASSHPVPAAIAAAFRCMGTEHPGVTFRHLDITPDIAHPDS
AETILAALQSAGESELALRADGMYAKRIQDADHDGDAKTAAPVPEHVVITGGTGKLGQEF
CEHYARLGTRQITLISRSGETDAVTGRLDAIRRSSGATVRALRCDVTDPGAVAELAAQLA
EAPADLIIHAAVDYSDIPLAEVTAAKFQEALRAKVGGIVNVLDAVPRTDSCRVMLCSSLA
ATIGGKGQLMYAAGNRMLDVLASRRRAAGLDCVSVQWGQWTVHLDLDDTGIAKLAAAGVH
PMRPADALAVGMGHHTDNALVGAFDLTQARAMLGVFGYGPLLSELEENSAPVPPAEVIRP
AVVVPENRSGHLVQLLAEVIGADHADSIDTAMPMVAMGLDSLQALEFRRRVQAELDFELP
VQDLLGGASVDHVIDALTAQTR
>I9NKA3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pelosinus fermentans JBW45|TrEMBL
MDNQFKLLYKQIKEQKISRQNAIEQIKKLKVQRKLQTAPSKSSFSIEEKKIVIAITPDLL
QEKAINYFKKLLSSEIKLPAQQIEADAPMDNYGIDSVMVMQMTNQLEKTFGSLPKTLFFE
YQNIQSLTGYFLEAYREQLIGLLGIEEIVATTESTKEYDAITGAVKQPVSSKRRRSRFAS
LHNEIPQEKLGALDIAIIGVAGRYPQAKNIREFWNNLRNGKDSITEIPKERWDHSLYFDE
DKNKPGKTYGKWGGFLDNVDQFDPLFFNISPRDAEMMDPQERLFLQCVYETLEDAGYTRE
ALSMQQGFGLEGNVGVFVGVMYEEYQLYGAQEQIQGRPITLSGNPSSIANRVSYFCNFHG
PSMAVDTMCSSSLTAIHLACQSLQRGGCELAVAGGVNVSIHPNKYLMLGQGKFVSSKGRC
ESFGQGGDGYVPGEGVGAVLLKPLSKAIADGDQIYGIIKGTAINHGGKTNGYTVPNPNAQ
ASVIGQAIKESGVNPRAISYIEAHGTGTSLGDPIEIAGLKKTFQEYTKDKQFCAIGSAKS
NIGHCESAAGIAGVTKILLQLKHRQLVPSLHSETLNPNIDFDNTPFVVQQELVEWKRPVI
EMNGESREYPRIAGISSFGAGGANAHVVIEEYISKNQQRPSITITTQKPAVIVLSAKNEE
QLCEQAQQLLAAIEEQAFSEISLADMAYTLQVGREAMEQRVGLIVGSSKELEEKLKSFVA
GQNSIEDLYRGQVKRNKETLAVFTADEDMAKMIETWMDKGKYPKILDLWVKGLIIDWSKF
YGDIKPRRISLPTYPFAKERYWVPEIETRVSSKIANQEIVNLIHPLLHQNTSDLSEQRFS
SIFTGQEFFLEDHIVKGQRVLPGVAYLEMARAAVEQATGRLAGDKTGIQLENVVWIRPIT
MGGQPVQVHIGLYPEDNGEIFYEIYSETEMADVEPIVYSQGKAMLSPVAEAPSLDIKALQ
AQCSQQIFTSSQCYEVFKAMGIEYGPAHQGIEKVYVGSDQILAKLSLPSTVLQTQDQFAL
HPSLMDAALQASIGFIMESETLLIKPFLPFALQKLEIYKKCTLSMWVSVRSSYGNIAGDK
VQKLDIDLCDDQGNVCIRMKEFTARMLEGEVTPIELAATIEALMLEPSWKEKAIGSEVTV
PVVYEHHLVMLCELDEVSPQSIETGMDGVRCLTLQCEHESIEERFQAYVVQAFEEIKSIL
KDKPKGKVLIQIGVPIQGEEEIFAGISGLLKTAQLENPKLLGQLIEVDQLADSARIIEIL
KENSLSPMDNHVRYQEDKRFVAGWSRVETSQEGIKIPWKDQGVYLITGGAGGLGLIFAKE
IAHKAKGVTLVFTGRTPLDDGKQGKIKELEALGALITYKQVDVTDKQAVIDLIQSIQDEF
GSLGGIIHSAGIIRDNFIIKKNKEELQEVLAPKVNGLVNLDEASKELSLEFFILFSSIAG
TFGNAAQADYSTANAFMDGYAKYRNKLVGSKQRQGQTLSINWPLWKDGGMHITEEAEKMM
MQNSGLNAMRTTTGIEALYQGIASGKAQVVVMEGDIKRLQTALLGQSFPTEVTRTSSTIE
EKKAVITIEQDFLQEKAIHYFKKLLSAAIKLPTHRIEADALLEQYGIDSVMVMQMTNQLE
KNFGSLSKTLFFEYQNIQELTGYFLASYRDQLTELLGIQETAAATMENSGENMADTEPVK
ADFSSRRRPRFAPLHMEIPKEKTRGALDIAIIGVAGRYPQAKNIQEFWQNLRDGRDSITE
IPKDRWDHSLYFDEDKNKAGKTYSKWGGFLDDVDQFDPLFFNISPREAEIMDPQERLFLE
CVYETLEDAGYSREALGLVQGFGLEGNVGVFAGAMYEEYQLYGAQEQIQGRSIVLSGNSS
SIANRVSYFCNFHGPSMTVNTMCSSSLTAIHLACQSLQQGGCKLAIAGGVNISIHPNKYL
MLGQGKFVSSKGRCESFGQGADGYVPGEGVGTVLLKPLLQAIAEGDHIYGIIKATAINHG
GKTNGSTVPNPNAQASVIGQAIKEAGIDPRAVSYMEAHGTGTSLGDPIEITGLSKTFQQY
TKDKQFCAIGSAKSNIGHCESAAGIAGVTKVLLQLKYGQLAPSLHSETLNPNIDFSNTPF
VVQQELAEWKRQIVTIDGETKEYPRIAGISSFGAGGSNAHVVIEEYIPSNQERPPIIITR
KNPAIMVLSAKNEEQLKEQVQRLLEVIEKQQFSDESLIDMAYTLQVGREDMEERLAMIVG
SIKEFGEKLKSFAAGQDDIEDLYRGQVKRNKETLAVFTADEDLQKALEAWISKGKYGKLL
DFWVKGMIVDWNKLYGDSKPHRISLPTYPFAKERYWVPAMETRIDDTITSKDNIHPLLHK
NTSDIFGLKFSSTFTGQEFFLADHVVKGQRVLPGVAYLEMARTAVEQATGVLTEDKLGIR
LENVAWVRPIAAKEESVRVHIGLYPDDNGEIAYEIYSGISAADAEPIIHSQGSAVLRPVS
EVPALDLKALQAECSQSILTGSQCYEALKTLGLEYGSGHRGIDKVYVSPEQVLAKLHLPS
AVIATQKHFVLHPSLMDAALQASIGFMMASGDMGSRASLKSMVPFALKEIEIIGNCTSDM
WALLRYSAGSKAGDKVQKFDVDICDEQGNVCVQMKEFSSRVLESAADSVVPSAKFRGLML
QPHWKEQSTNPEAVANANAQHVVMLCELSGAYCESIETNMSGVRCLSLQSDQESVEERFQ
TYAIQVFEEIQNILTYTHKGAVLIQIVVPNQGEGQLFTGLSGLLKTAQLENPKIIGQMIE
IEAEGLLKEEIIEILEKNSQSFVDKHVRYQGGKRWVNSWKEVVVSEEEVGIPWKDNGIYL
ITGGAGGLGLIFAKEIAQKVKEPILILTGRSSLDEGKQAKIKEMESLGALIEYKKVDVTD
KQAVMALIQSIRDKFGNLHGIIHSAGVIRDNLILKKTEKEMEEVLTPKVAGLVNLDQASK
EMSLDFFILFSSIAGSVGNVGQADYATGNAFMDAYARYRNVMVMSEERYGKTLSINWPLW
KDGGMHVDKATEKILQSMGMIAMQTSTGIQVLYQSLVCGNDQVMVAEGDVKRLRNLMELE
>A0A378RB04|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium aichiense|TrEMBL
MTAGITPWTLSAKSASALAGTAAALQRALHEHPDTDPIDVAYSLGGDCAPFRHRAVIVGA
GRGELLAGLRAIASGTPSPGVITGRATRAGRTAFVFPGQGSLWVGMAGELLDTAGAFATE
MRRCDDTFAEFLDWSLIGTLRGEPGSPDVGGDDVAQPILFAVMVSLAAQWRALGVEPDAV
VGHSQGEIAAAYVAGALSLRDAARVLCAQCEAITDVVGSGSTVFIPEPVDQVCELIGPWD
GSIAIAERNSPSSTVVAGSAVAIADLVARCERDHLPVKRIPLPYASHSVDMEELRERLRQ
QLADVRPKPATVTFISTVTGAAAGAAVLDGDYWFANLRQTVLFEDAVRWAYGRGHRTFIE
CSPERALSADIEESLDACGDDATVVGTLRRDDSSMRRFLMSLAEAHVRGTSPNWTSVLGA
CAGRPES
>A0A5A5RPJ9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Microcystis aeruginosa NIES-2520|TrEMBL
MKPIAIIGIGCRFPQANNPQEFWQLLSNGIDGITEIPKERWNINEYYDENPETQGKMNSR
HGGFLSQVDGFDPNFFGISPREALLMDPQQRLLLEVAWETIEDAGITREQLAGSKTGVFV
GIATNDYSRIHAGYSHHPQGYDLTGNCTNIAAGRLSYLFNLKGPSLAVDTACSSSLVAVH
LACQSLWNDESSMAIAAGVNLILSPIGHIALSKLKALSPDGRCKTFDESANGYVRSEGVG
CIILKPLAQAIADKDSIYALIRGTAINHDGRSKGLTVPYGPAQESLIRSALKNAEIEPKE
LNYVELHGTGTSLGDPIEAIALGSVLEEGRDKDNPCLVGSVKSNIGHLEAAAGIASVIKM
ALSLKNKQIPPSLHFNKPNPYIPFDKLPLKLQSSLITWPQQETTAKVGISSFGFSGTNAH
IILEEANLSHQEPISLTFPHLLPLSAHSHEAVRDLTQNYEDFLKDQALTAEFVQNLCYSA
SARRTHHAHRQAVLVHSPEELLKGLKELETIDLSTQSKPSKRKTNIAFVFSGQGPQWWAM
GRELLATEPVFRSVIKQCDTLIQKYANWSLLAEFNASEALSRLQETEVSQPALFALQVGL
AKLWQSWGINPKSVVGHSLGEVAAAHFAGILTLDEAIHLICQRGQLMQQATGNGKMLAIE
LPVNEVENLMAAWENKLEIAAINSPYSTVVSGESQSIDQLIAELSQNHLHIFYKELPVNY
AFHSQQMTTFADKLVKKLGELKPQKSTIPIFSTVTGDQQEGTLFNAAYWGQNMRQTVRFN
PAIEAMIKSRHTIFVEISPHPVLLGYIKSTLREQDTEGFVLPSLRREHSERGTLLNSLGK
LYTWGHSINWEKLYPENCQFVKLPLYPWQHESYWVSDAKPQFKSVSSASSLLNLLVEGKT
EQLTEQLNQSDQLSPEVKQFLPQLLQLLVGEDTTIAGQMPILQDVSKNCYKVEWQLSPLN
LKNKPSQGERWLIFNDNQGVGKALATTLNDAYVLVSSGQTYQKLVSGHYQINPNNVKDFQ
RLLQDLTEPITKVVYLWGLDSDINSQPSQTRSYASLLYLTQALAQFKTKEPPKLWVITQQ
AQPVNDAVKPLKIAQTSLWGMGQVIALEYPNLWGGLIDLEEKQPSSQAIIAEITENLGED
RIAFRDHQRYVARLVPNKAIKSSNINFKKTEASYLITGGLGSLGLSLADWLIEKGANHLI
LTSRRALADHSTDKQVKIKALEDKGATIQVIAADVSDHQQTRQLFHQIQENCPPLQGIIH
AAGVLSDRTIDKMDFHCFESVFNPKAAGAWNLHQLSQDLSLDFFVCFSSMSALIGSRGQI
HYAAANHFLDGLMHYRRESGLTGLSINWGPWAKGGMATQGYEEGLKRLGINPLQPNLALD
TLDALINGNVTQTMVAEIDWSKFKTIVAAKGRVAFLEALFKQDKDNFVQTVENFPQTIQK
NPPHRRVTLLTTRLQQEVAQVLGIHGDTLPDTDQGFFEMGMDSLMSVELKHRLEGLFSVS
LPSTFAFEYPTIGDVVQYFVQEVFAWQDNSENSQISSETESTDVVVLHQALAELESLSEV
ETEALMERELAELEALL
>A0A0N1G4G9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MTDRPYDDSALQGRIAVVGLDCRLPGARNPAEFWHNLLAGTDSISDVAEEQLEAAGVPAR
QRADARYVRRAAVVEDTDLFDASFFYLSAREAERMDPQLRLFLQSSWTALEHSGHDSEQY
AGRIGVFAGSLSSTYLLDNVLTGERGFKGSVRAMRQDLATMMGNDPNYLATRASYHLNLT
GPSISVQTACSTSLVAVHTAAQSLLSHECDVALAGGVALRFPQEAGYLHETDGIASATGT
VRPFDAGADGTLFGNGVGVVVLKRLEDALAENDTVWAVLCGSAVGNDGADRAGYTAPGVS
GQAAVLAEALAVADVAPESVTYLETHGTGTLMGDPIEFAALAQSYQVDGAPPLRLGSVKA
NVGHLSAAAGVTGLIKCVLMLHHRTLVPTPHFTEWNPECEVEGTRFRMGTAVEPWETAGG
PLRCAVTSTGMGGTTAHTVLEEAPAHRAGDRAGAAGGGLVVLPVSAKSPAALETARTALA
DHLETTAPEGADPGLADAAYTLATGRRTFNYRAVVTAPDRATAVQALRTGDPRFVHQDSG
QPADRPVVLLFPGQGAQYPGMGQGWYEQLPVFRAVLDECAQLLLPRLGFDLRDALYPELR
GYEGERHDLNRTRLTQPALFAVEYALARQWTTWGIRPAALIGHSIGEYVAATLAGVFSLP
DALHVVAERGRLVDELPGGVMASVMLSPAELEGYLDDDVALAAVNEPAVCTVAGTREAVG
RLTARLTADGVAHRKVVTSHAFHSPMMEPAVEQLTEVLRQIELRRPHIPFLSNRTGTWIL
DDEATDPAYWGGHLRATVRFADDLATVLAEDRTVFVEVGPGQTLATFTRRHPDRETGVPV
LTSAARGRAATDVTAVHAALGRLWAAGLTVDWAGYHGGQDRGRVPLPTYPFEGVRYWVEP
GAAEVSGTRGGTAAPVGKLPVDEWLSAPVWRQAVGALDAPVEPLGEPVLLFADADGVAAR
LTEHAFAGEVFTVAAGDAYARDGDTWTVRPDSEEDHGRLVADLLAEDRLPARVVHAWAAG
QLPAERGIERFEQAQRTGLYSLIALVKALSAQGVTRPLQLDVVSAGAYAVSPAEPEPASE
LVTLGVAARVVGQEHGNIGSRHFDLPAPVDERSLRTLAAELTGFRRPEVAVTLRGATRWT
ADMAPVRADWTATAQSRLRERGVYLITGGLGEIGSTIARWLHGECGARLALLTRDALPPR
EGWDDWLGGHDADDETALRIVRLRALEAAGAEPFLVNADVADEAGLRAAVERVEAHFGAL
DGVVHAAGLPSEQWDRAITAASVEQCQWHFVPKAHGQIVLEKVLADHPVDFCLLLSSLAG
VLGGLRLLGYGAANHFMDAAAERANRGLDRTVWISAAWDVWQHHQDEKRALSAIGRSMDD
KAIQPDEGLEVIRRLLTLRDISHVAVSTWDIGHRLDQWVRDDRVARPSAGVAAEPDDAAA
GLSSDGDRDLTEQVTRMVRHSLGTEDITPDGDIFEFGGDSLLIVKLLSDVREQFSVEVPL
ADVLGEPTSRALAALVQERLDDRRDSGPSAPGDDEVDELAAELAALGADEIERLLAEAEA
GPDAARTAGEQEH
>A0A0N0N6U1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MSPAPPPSRAQIHDLVAGRLHAWYGIAPDDIADDRPLAELGLTSRDAVALAALLGERVGR
RLPDTLLWEAGTVDAITRKLTERQPVAEKRTLTAPDADTAVAVIGVGCRFPGGADSPDAY
WRLLAEGRDAVATVPDGRWDAWPGGVPAAVPRHGAFLADIAGFDAEFFRIGAPEATAMDP
QQRLLLEVAREALDHAAVPVESTRTGVFVGISGAEYAHLTAAAPDAWTATGGSPSIAAGR
LSYVLDLRGPSMAIDTACSSSLVAVHHAVRALAAGECDTALAAGVNLLLAPAVTLAFQRV
GALAPDGRCKAFDAAADGIVRGEGCGVVVLRRLADAERDGDRVLAVVRATAVNSDGRSNG
LTAPNGQAQQALLTEAHSAPATVDLVEAHGTGTALGDPVEAHALAAVLAAGRDPAQPLLV
GSAKTNLGHLEAAAGIAGLIKTVLALHHDEIPPHLHYTRPSPHADLDALGLRVPTEPEPW
PRYSGTATAGVSAFGFGGTNAHVVLTEHRASARTVTDRQHLPAVLAAPTDDRLRAYAGEL
ADWLAGHPRVRDADLARTLAGRTERGHHRAALVTRDRTATLTALRRLAVAEPTPHAVVGR
TRPTGPGPVWVFSGYGSQWPGMARRLLTAEPEFAAAVEELEPLLRRHADISLTGSLAPEA
DLSTPATVMPALYGIQVALARLWRSYGFAPAAVIGHSLGEIAAAVVAGALDPETGARIVA
VRSRLLARLSGGAMAVVDRPAEEIDTLAQELTSLTVAVHASPAQSVVTGSAADVAALVAR
VSAEGGFARALPVTAAGHSREVEPLLGEFAREIGEVRTAEPELPYYTTVLDDPRELPGYG
TAYWAANLRRPVRFAQAVRAAAEDGHRVFVEVAPHGTQTHALTETLPDDALVVPTLRKGT
DDALTFRTALATLLVNGVRATGERELPDGRIVDVPSPRWRHRRFWFGEKPPEPMRAAPAA
DGDGGTVGRLRHCVAAVMGFGPERLDPDLPLTDLGLDSLTAVRVRAAVEREFGVDVEPGV
LLRRGTLRAVAELLPTAPQTPPLRAFPGGGPRTPLFLAHAAGGDSQVYAPLAQLLDGDRP
LYGFDRLEEPDDVPGRAGEFARRIRAVQPKGPWAVGGWSYGGVLAQEVAHLLSAHGPVAA
LVLVDSVLPLPAPPGETPGDTARRRFTGFAEYVRHTYRARLDLPFDDLAELDDAGQIDLV
LKVLAATVELPPSVLEHQRTSYLDLRSGERHRPRPYRGRTLLYRATEAAPHTVRDPRYER
TDATLGWDAHCADLTVTELPGHHLSVLDPPAVEELARLLGRDLGDRP
>A0A0N0N226|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
GPSRGWRVRAPAARPGAARPPPPPPPASPATVVPLLRPGIPERLSLLTGLAELHVAGAGT
DWSGLFGEGRRERVDLPTYAFRRRPFRFAASARTEDATASDPGTATALPRTTVAPQESVA
PQTSVAAAQKPTGQAAAPAAPTTDTDPLPLPLVLATAADVLGVAPGQDLDPERTFKALGL
DSLGAVEFADRLSRASGLWLSPTLTYDHPTPLALARHLATQAADSAVEAPKHTGDAGRTG
DARDLDDDPIAIVSTAGRWPGGADTPEQLWDLLVAGTDATSGFPVNRGWDEDLHDPDPDR
PGASYVRRGGFLHDADRFDPDFFGLSAREAEAMDPQQRLLLETSWELQERADVDPATLRG
SGTGVFVGATQQEYGPRLHEATGQAAGYRLTGATVSVASGRIAYAFGFEGPALTVDTACS
SSLVALHLAVRALRSGECDLALAGGVTVMATPGMFTEFSRQRGLAPDGLCKPFAAAADGT
GWSEGVGLVLLERLSDARRAGRRVLALIRGSAVNSDGASNGLTAPNGPSQERVIRQALAD
ARLAPGDVDAVEAHGTGTTLGDPIEARALINTYGQTRPAGQPLRLGSLKSNLGHTQAAAG
VASVIKMTQALRHGLLPATLHVDRPTPHVDWSAGTVELLTRNTPWPDTGRPRRAAVSAFG
ISGTNAHLVLEEAPPAPVEPERPSSERLGSEPPGSELPGSELPGSELPGSDRDFPDRDLP
VPWVLSARTPQALQDQAARLAARLAALLDRPEPTGPGPAAADPADPAEVGHALARRPVFD
HRAVVVARRPADFRTAVRALSRAEPAEAVEGVVRGRAATPGKVAFLFTGQGSQRPGMGRE
LYAAHPVFAAAFDEACAALDAHLAGYAPAPLREIVFAPEADRPEPDGTDPGARPPGAPAR
ELDRTVYTQPALFAVEVALFRLLESWGVRPDVVAGHSIGELAAAHVAGALTLADAAELVV
ARGRLMQDLPEGGAMVAVEASEEEVRAELAARATVVDIAAVNGPSSTVISGEEAAVVATA
DRFRARGRRTNRLRTSHAFHSPLMDPMTAELDRVAGRLTQLPPDIPLLSALDGSLFTHDR
PVPPGYWAAHARGAVRFLDVVRRLEADGVTTYLELGPDAVLTALAQEGLLGVLGDDTPPP
ALAALLRRGRPEPETLLTALGAAHARGADVNWSAVIGLTGPSRVDLPTYAFQRRRHWFEA
PGNQPVPGATPAHDSGFWELVERGELDALATTLGISDTGHRAALDAVLPLLASWRDERNR
AAETDSWRHRVRWQPVLDPAPRAVRGRWLILLPERADGATRPYDAWGPLLEGTLTDAGAR
VDRVAVPFADTRPDRVSLAAQLTEAVGPSSREPVTGVLSLLSLEHDPDPELPAVPGGFAA
TVALLQALDDVGVEAPLWCATRGAVTTGTGDPVTDPTGALVWGLAVVAATEAPGWGGVVD
LPERADPGAAAHVLAALTGRHREAELAVRPEALFARRLVPAPAPPTPAPPAPASPDRAGT
DAPGWTPRGTVLVTGGTGALARHTARRLARKGADHLLLLGRRGAEAPGADALRAELTALG
ARVTFAAGDVSDREALARVLASVPAEHPLTAVVHTAAVLDDAPLAALTPEQLDRVLRVKA
VGARNLDELTRDLDLSAFVLFSSATGITGTPGQANYAPGNAYLDALAFRRRAAGLPATSV
SWGLWAGEGIADDGAARRTERYGLLPMAPELAVAALEQALDQDETHLVVCRGDWTALAAL
RSHPLLEALTGPGTATDDDGPEPGDEPAALLQELAATEGEQDRRRLLLRFVRTQVAEVQG
GRPADSVDVHRGFKEQGFDSLTTVELRNRLNLRTGLNLPTTVVFDHPTPHAVAELLYARL
VPEEDPAAGTAQEPPGPDRLDTLLSAATDDELIDFIGRELGIS
>A0A0N1NKT2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MAVVGMALRFPGADTPAAYWRDIRAGVSHVRPFTRRELAASGVPEDVLDDPDFGGASALL
DDGVDGFDAGFFGMSGREAELTDPQQRLFLECCELALEDGGYAGPGASDDRRDLGDLRDL
RDLRDLRDLRDLRDLRIGVYGSVGYRLYSLHSYLGANVLAGGGSTANGTANGTTEGKTAD
GTTTGAADWTTDWTTAKQIQVGNYPDFAATRAAFRLGLRGPAVTVATACSSALVSVHLAC
RTLLAGDADLMLVASSALHLPQITGHRHVPGSTVSPTGTVRAFDAAADGTVGGNGAAAVL
LKPLARALADGDTVHAVILGSAVTNDGADKGRYGTANSPSRHGSFAAPGVTGQRDAVLDA
LRDAQVTPDEIGYVEAHGTGTYKGDPIEFAALTEAFRRHTDRVGFCALGSTKPAIGHLDS
AAGLAGLIKAMLVLPPGVLPPLVNLTRPNPELGVDKSPFVLPRTATLWQGDGVRRAGVHS
IGMGGTNAHVILEQAPPPPPRPADPSPTPALLPLSAATPEALTAYARAFHDTLVRDPGLA
PADLLTTTALGRRHLRHRLVVTAPAAELADALGAFVAGRTAPLPTGGGDP
>A0A6C0PVZ7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. S4.7|TrEMBL
MEESATQDKLRDYLKRATTELERSRLRVRDLEEQYREPIAVIGMGCRYPGGARTPEDLWR
IVADGTDVVSGFPLDRGWDIDALYDPEPGVPGKSYVRHGGFLHDAAESDPSFFGISPKDA
AGTDPQQRLLLETSWEAFERAGIDPLSVKGTPTGVFVGLMHHDYVGGTISGSIVSGRIAY
TLGLEGPAVTMDTACSSSLVALHNACLALRRGECTLALAGGAAVMASPEMFVEFSERRAL
SPDGRCHSFSEDAAGAAWAEGAGMLLVERLSDARRNGHEVLAVIRGSAINQDGASNGMTA
PSGPAQIRVIRQALADARLAPHQIDLVEAHGTGTTLGDPIEAQAVIATYGQDRPKDRPVR
LGSIKSNMGHPQAAAGVAAVIKVVMAMRAGVLPKTLHAERPSTAVDWTAGDIELLTEALP
WDAADAPRRAGVSSFGISGTNAHIIVEEATEPEAPRPGSGPELPVVPWVLSGRTAEAVRA
QAGRLLDTVDAYDPADVGFSLATTRSAFPHRAAVTGRDLAELRAGLDALADGRETPRTVP
EPGRLAVLFSGQGSQRPGMGRELHAAHPEFARVLDEISDAFGEHLEQPLREVMFDPESTL
LHQTAYTQAALFAFETALYRQLESWGVRPDLLGGHSIGEIVAAHVAGVLSLPDAVTLVSA
RGRLMQALPTGGAMIAVAAPEGDVAPLLTDGVDIAAVNGPRGVVVSGDEEAALAVAARFE
KTNRLKVSHAFHSHRMDGMLDAFLDVLTTLTFHPPKVPVVSNVTGLLAGDEFTTPDYWVR
HVRGSVRFHDGVTTLAAEGATRFLEVGPDAILTGMAQDVVPDVIGTQRRDREETKALMDA
LCLLHTSGQGPDWQAVFAGARRVPLPTYPFRRDRHWENAPSLGFGAPAQPDAERGDAFWQ
LVTDGDVGAVAATLGVTDESAVGAVLPALADWHGKRQANSEVDGWRYRAGWRPLAVPETA
VRGRWLAFVPETSADDPWLKTVLTGLADRGLDIDTLPVPDDARDRAALAALLTNRTDTAD
GAEPAGVLSLLALEHPVATTAALVQALGDAGLTAPLWCLTRDAVAHAPGDTPTGFRQAEV
WGLGRVAALEHPDRWGGLVDLPAEPGHRTPGLLAGVLTDGGGEDQLVVRESGAYARRLEH
VPHRPGGAPWQPTGTVLVTGATGAVGQHVARRLAADGAEHLLLVSRRGPDAPGADDLVAE
LTATGVQVTLAACDTADRAALAALLDTVPAAHPLTAVIHLAGVLDDGVLDSLTPERFAAV
LGAKAETARHLHELTKDTDLCAFVLFSSLTATVGGAGQANYAAANASLDALAEYRRATGL
PATSVAWGPWGGGGMAFDHTVRDAGRALGIKQLDPERALTALRRALESGDTVVTVADVDW
AKFASAFAAGRPAPLFGDLPEVQAAPAAADAPVADDFARKLAGLTAGERERALEDLVRGQ
AATVLGHGSADGVEATAAFRDLGFDSLSSVDLRNRISAAAGVPLPATLIFDYATPAALAK
YLGTELAGAEESVDSVLAELDRLAARLADLSAEDLQEGRVTSRVRAVLNGLDERVADGGS
AVAGQLEEATADDVFAFIDRELGSA
>A0A5P9D1L2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Labrenzia sp. THAF82|TrEMBL
MKHISLDAGNSPVSVVGAACRLPGGISTPQDYWQFLESGRRLTASPPGPDRFSSSALASP
SGAPPANYLSGVDLFDAEYFGISPREAMRMDPQHRLFLELAISALEDAAVPTDSLAGQSV
GVFLGLYGSDYAWLPEAASCPPDVHSASGGGPVFAANRLSHFLDLRGPSLAIDTTCSSSL
VAVHLAVNALRSKECDLALVGGVNLILSAEVAASSASSIPAAKTGRCETFSKHANGTVMA
EGGVVLVLRRSTDNPLPGGREIARIQATAVNHDGQASSLTTPNPDAQKDVIMRAAGQNGI
DANKIAYLEAHGTATELGDAFEIEGACHAYKSLRSSEIPVPIGSVKAQLGHLEAAAGAAG
LLRACLSLDRGKVTAHPLEGEANDLFSRQTTVIPATEPVRLDRDHLIGVSAFSLGGTNAH
IVVGAAPAESKSELSGATNSQCIIFPISGKTANALANQLESHIRFCDSHAHDTVPLESLA
GTAAGGRMAHAYRTSVVAETKAQLRAGLNRARQALANGQTPKRVTAADRDVVFVLPGHGA
QCAGMAQGLLGKDPVFDRAVTRLDAEFATYCDWSVAKLLASSGNGAKLQDARYAQPALFT
VQIAMAECLMARGIELSGLIGYSAGELSAMVLSGMLEEETAVRLCSQRAQRLSTAPPGKM
VAVRMPVDDLRRLIAGKTPDIAVAAVNGPETTILSGPAESLTSLAQTLESKGHLCIDTGI
AYCFHHPAMTEASRNLEQLFGTTETRWSAPRVPVYSCVTGARLTPDDLTRDYWQRSACAT
LRFDMAAEAALSDGFKTFLEVSPTAVLTGDLRDCMRLSGRKAVAVATLRRGVPDRRALAI
AGSELFNAGALSSVVPFNPEGGQWVDLPSYAWQRASHWWPPLRKDTPEKAANNSAPSIST
ENRKLYYLDWVETAAPCKVSGDTVRRTNMAAAEEAETQRLSDYDHHADLIEKICGHYSLV
TLQKLSQGQTIPEPSFLADRHQFERHERRLLHCLFTIARRSGCLRQDGPNNSPATLDFDL
IKALEIVRRDVPAIAPELDMIERTGPFIADVLLGKRQALDLLFPDGTANDVADVFSASGI
AKVMNGIAAGVIKGLLRERIGAAPLKVLEIGAGTGGTTAEILPLIEATGGSYTITDISQT
LLRFADKRFSDHSSPVFQRLDISASPDTQGFSGAAYDVIICANVLHATPDIAQSLTHVRN
LLAPGGLLLLCEAVAANPLVDLTFGLTRDWWNYADIALRKDHPLLSGESWTGVLQTQGFE
DIRLLPTEKSLSDTLQNAVICANTPPEQAALLLKRHWLVIGKDGALRHHTAKALTAISPN
VTQVTSLETATLNNLRDDLPLGIVDLRFLAPRVQEGAGAQHLVDQFRKAVPGLLKTIQVL
AGRPGPAPLLVIPTAGATRPIMSAAPADPLQAGLAGLAETIAAEHQDWDVRCPDIHPATV
PSVANVVLRELRSPRQEARTAVTGAKRHGARIRLEPAGTTPKPDLDPEALFVVTGGTGAI
GLLTAEWLANRGARRLLLAQRGRGSEAAAQRCRKLQDHGLTVTMESVDFADPDAAARFAD
DLISRKPAGIVHAAGIFSDRLLMSQDWRGFEAALGAKIVGGWEAYRVLSACPDAFLIFCG
SSAGLLNPSGLGNYSAANAFLGSLAAHARAAGLKATSLNWGGWSDLGMATRQSDRWFERW
QQLGVKSLAPQDLFETLDLAAAGTAHAETWVMDVDWDLYAEGQPDWRRNLVSNLVARTPA
SNPKSVSLAGTTQSDTPKTAGPLLEPGASSEDRREKIMEIVRERSLVVLELAEHFDIEPD
LPLADLGLDSLLALELRGDLCDIFGLPLQHTLLFDCPTLERLVDHLDTEFQRNRTCP
>A0A1V2RCB5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MAEEATDGLLRTLADRGTTAERLDVGIEDMDRGKLAARIAERAGDGSGLAGVLCLWALDD
SDHPDLLGTSVGSAGGLVVLQALHDLSFTAPLWMLTRGAVSVSGSDHLTSPGQAQTWGWG
RAAALEHPDLWGGLIDLPARLDDRALRRVCQILADPDGEDQLAVRSSGVFVRRLVRGALG
DRTPPRQWTPRGTVLVTGGTGGIGGHLARWLARNGAEHLVLTSRRGREALGAPELEAVLT
EMGVRVTIAACDVADKKALSELVRQVEAEGPPIRAVIHTAAHIALGMLAETTPADYAEIC
RAKVLGAQYLDELFDKDTLDAFVLFSSIASVWGSGDHGAYAASNAHLDALAEERRGRGLP
TTSVSWGIWDAANDWDPLNTELRTYKNQKSSRHGLPLLDAELAFAALQQSLDHDETFVAV
ADVDWEQFVSLFTMVRDSRLITEIPEVRRLKEAPLPESAGTSAATGQFAEKLVGLSRPEQ
EHLLLDLVRAQAATVLGHGAAGDEVEAGRAFRDMGFDSLTAVELRNRLEAQTGLKLPATL
VFDYPSPTHLAARLLVMLAPEDSAAKPVLGQLAELEAALGALEPDESTREDVAKRLQNLL
WRWNESASPAPSSGVDGDGADAADTGNGGVDVSSASADELFNMIDRELGLP
>A0A1V2RC94|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MTSSSPTASTDKLVQALRASVAEADRMRKQNQQLRAAATEPIAIVAMACRFPGGADSPDE
FWRLLDEERDVVAAFPDDRGWDLETIYHPDPDHAGTTYVRGGAFLPRVGDFDAAVFGISP
REALAMDPQQRLFLETSWEAFERAGINPLSLKGSRTGVFAGTIASDYTSMLRTMPPEVEG
YLGTGNMTSVVSGRVSYAFGLEGPAVTIDTACSSSLVAIHLAVQSLRQGECTLALAGGGT
VMSTPYGFIELSRQRGLSEDGRCRAFSADASGFGPAEGSAVLLLERLSDARRNNHPVLAV
VSGSAVNQDGASSGLTAPNGPAQQRVMRAALQNARLRPADVDVVEAHGTGTTLGDPIEAQ
ALIATYGQERAGREALWLGSVKSNIGHTQAAAGVAGVMKMVLAIRNGRLPRTLHADEPSP
HIDWDTGEVRLLTESRAWHAGEQPRRAGISSFGISGTNAHVIIEEPPRAEAAGSAEPGPQ
PPAAPGTPAVVLLSGLSRTALREQASRLRAHVAAHPEIGLPELAASLARTRAMLPERGLV
LATDRDALLDSLDALAEGRPSAEVIEGTAGTADRVVFVFPGQGCQWAGMALELLDTTPAF
AARFAEAAAAVEAETDWSVEAVLRGADGAPDLERVDVVQPVLFVVMVALAELWRTHGVRP
AAVVGHSQGEIAAAVACGALSLAHGARVAVRRSRLIGRRLAGHGAMASLARSREETLALI
TRWGGRLSVAAANGSSSTVVAGDPAAVEELIAACAEQDVRARRIPVDYASHSPQVEEIRE
ELLRELAGIEPRTSDIPFYSTVDGAPVDTAGLDADYWVRNLRQTVEFEKTTRCLEEAGHT
VFIECSPHPVLTMAVEETTGSDCTPVGSLRRDQGGPARFLTSLAEAWANGVGVDWSSLPG
DPMTAVAGLPTYPFQRQRYWLEQQVEAVTAPAPAGEETETRFWEAVDRGDLTALTSELGI
DADRPLSDLLPALALWRRRNAARDTIDSWRYHVTWKPLPVSATGRLSGTWLVMAPAAGAE
RAATVVGGLRAGGAEVVVVQFDEPSLTRAALAARLTDLTAALPAPSGVLSLLALDPATAL
PHTMLLIQALSDAGVPAPLWCATQEAVSAVSADTGADALQAEQWGLGRAAALERPPHAWG
GLVDLPEHLDDRALARLVTVLAGLEGGEDQVAVRAAGVFGRRLVPAPFGDKAPSRQWRPT
GTVLITGGTGRIGVNLARWFAENGAAHLVLTSRQGDAAPGARELERELTATGVRVTLAAC
DVARRDELAALLSTIPADLPLTAVIHAAGSTEGMPLDAMTPEDLERIRSAKVDGARHLDE
LLGDQHLDAFVLFASHTAVWGGGNQSAYSAANAHLLALAEQRRARGLTATSIAWGVWGGG
PIVNDEAFLDHMRRRGIREMLPDLAIDAMVQAVEHEETSVCVTRVEWETFAASFTSGRPS
PLLSDLPDLRRARLAAVRQEAAGVAADEKRSTSELTRRLSAAAPAAREAILIDLVSEQAA
AVLGHTSTEAIGPNRLFRDLGFDSLTITDLRKRLSSATGLTLPASLVFDHPSPGALARFL
QGELLGSAVGVDERRERPGTAVAPDEDPIVIVSMSCRLPGGIERPDELWEALVNGRDMVS
APPADRGWGSGAVEEDEEDTPLGGALRRIREAGLITGITEFDPEFFGISPHEAVVLDPQQ
RILLELAWETLESAGVNPRAGTREQIGVFTGISYQGFNPGPRIPKDSEPYLGASGSPAFA
SGRLAYTLDLNGPTLTVDTGCTSSAVSLHLAAQAVRNGECDLALAGGVTVLAHPYAWFQL
TGGAAEDGRCKPYSDEADGPGWGEGGAMVAVERLSRARSLGHPVLAVLRGSAVNHKGASN
GLTAPNARSQQQLIEQAMANAGLTPGEVDAVEGHGTGTKLGDSVEVEALLATYGRERQAG
EPLRLSTVKSHIGHSQNASGVTGVIKGILSMRHGLLPGMIHVKRPVSDVDWSTGTVDLVT
ENEPWPQTARPRRVGVSSFGASGTQVHLILEQPEADVAPTPDGPVGTGESALPFPLSGRS
AAALRAQARRLRDHLVDRADLSLTDVGYTLSAGRAAFEHRAVVLAGNRAELLDGLAAVET
GTTAPNAIAPPSPAEGRLRTAVLFTGAGGGAQELYDTFPVFAEAWDAARAHLDVRLASLP
PSAEAFLREVALFRLYESWGVGPEKLLAAESGGPAAAHAAGWLTLEDAAAVICALASDRP
VEELATVLGAVAFGEAGLPVFTVGSTRPLTADDLAGSGFWQALPPATGTAEPGTIALHAT
SVRDALSAPAGLYAHGGDMRWEAVFEERGAQLTELPTYVFQRERHWLGEPSAPFDSRDYQ
HFAIAPTPTFKRKLMLDEQKRKDIVLEYFDKLNSGKLEDILAMFADDAVVEDPYGQAKHQ
GRAAVREFFTTVLGTDINIVPGRPSAAADGKLVAVPLTASLINTTDAEGPRVRVQAVDLF
EVGADGRIESMKALFGLSDISPE
>A0A378W9E8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium senegalense|TrEMBL
MDETQSNSNLPDGTEPAAAPASRPDLTVAEMREWLRKAVANATGQSADAIDESTPLIELG
LSSRDAVAMASDIEDLTGVTLTATVLFRHPTIESLATVIIEGEPEPESTDDEDWTREVVD
EDSYNIAIVGVATRFPGDLNTPDEMWEALLAGKDCITDLPEGRWEEFLSEPRIAERVAKA
RTRGGYLSDIKGFDSEFFALSKMEADNIDPQQRMALELTWEALEHARIPASSLRGGSVAV
YIGSSNNDYSYLSLADPTVTHPYAITGNQTAIIANRVSYFYDFRGPSVSVDTACSSSLVA
AHQGVQALRSGEADVAIVGGVNALITPLVTIGFDEVGGVLAADGRIKSFSSDADGYARSE
GGGMLVLKRVSDARRDGDQILAVIAGSAVNHDGRSNGLLAPNPDAQEEVLRRAYKDAGIS
PRSVDYIEAHGTGTILGDPIEADALGRVVGRGRDADKPALLGAVKSNVGHLESAAGAASL
AKMTLSLANDKLPPSINYAGPNPYIDFDKEHLKVNDTVSEWPRYSGHAIAGVSGFGFGGA
NAHLVLREVLPSDLVEPQPEPEAVEDKSASDEANAVYVGGVRMDEYGEFIHDDDESGAGD
GEYPAYDEANHELPGLTDEAKRLIEEARAQLEAADAAEPVNKVVPLAVSAFLTSRKKVAA
AELADWIDSEEGRASSLESIGRSLSRRNHGRSRAIVLAHDHDEAIKGLRAVAEGKQHPSV
ISADGPVTNGPVWVLAGFGAQHRKMGKELYLREPVFAEWINKVDAHIQDERGYSVVELIL
DDAIDYTNETCEYPIEVVQTVIFAIQVALGEFLKAHGAKPGAVVGQSLGEAAAAYFSGGL
SLADATRTICSRAHLMGEGEAMLFGEYIRLMALVEYSADEIKTVFADYPGLEVCVYAAPT
QTVIGGPPEQIDAIIARAEAEGKFARKLQTKGASHTQQMDPLLGELSAEIQGIEALPLQT
AYFSTVHEGKFIRAGAEPIHDVEYWKKGLRHSVYFTHGIRNAVDNGHTTFLELAPNPVAL
MQVGLTTASAGLHDAQLIATLARKQDEVTSMVTAMAHLFVHGHDLDLRTLFPRKSTGLAG
ALDFANIPPTKFKRKPHWLDAHFTGDSSAVMPGNHVATPDGKHVWEFVSKGTTDLAALVK
AAAAQVLPDARLTASEQRAVPAEGSRLVTTLTRHPGGASVQVHARIDESFTLVYDAIVTR
SGAATTLPTAVGAGVVAEQVSAAPAVAEPEPEDDAEILSDNLTKGAGMGAGFEKWSPDSG
ETVAQRLGTIVGAAMGYEPEDLPWEVPLIELGLDSLMAVRIKNRVEYDFDLPPIQLTAVR
DANLYNVEELIKYAIEHRDEVDQIAESQKGKSAEEIAAEQSELLGGASTVAELEAKLAEA
GHPLADKESEDTGPDPAAEAAATEGLEIPPPPTDPSGPAIPAPPTDPSGPSKATAAAAAA
KVLTQEAVTEALGADVPPRDAAERVTFATWAIVTGKSPGGIFNELPFVDVETATKLSERL
SERAEGTVTVDQVRAAKTIEELATIVRDQLEEGVVDGFVRTLRPAKEGGPQVPVFVFHPA
GGSTVVYEPLMKRLPADTPVYGIERVEGSIEERAAEYVPKLLEMHKGPFILAGWSLGGAL
AYACAIGLKQAGADVRFVGLIDCVRPGEPIDQSQAGMRARWDRYARFAERTFNVEVPEIP
YEELEKLDDEGQVKFVLEVVAQSGVQIPGGIIEHQRTSYLDNRALDTIEIQPYDGHVTLY
MADRYHDDAIVFEPAYATRQPDGGWGDYASDLEVVHIGGEHIQAIDEPYIAKVGAHMSEA
INRIEAESESK
>I4I9Q1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Microcystis sp. T1-4|TrEMBL
MMTTNLSSFSPWSTEISSGDRAEPVTLVKLLKYRAVQQPNQIAYHFLTDNQDIPAKLTYA
QLDRKAGAIAACLQRFHPENQCVLLLYPAGLDYIAAFFGCLYAGMIAVPAYHPKPNRSLE
RIKAIMKDSQSKIALTTSEISQNLERCFEFAPELKDLSWLTTDQIDGNLADQWQEPRINP
EDIAYLQYTSGSTCTPKGVMISHQNALHNTYDMAQTWDISGESVIVSWLPHFHDFGLVFG
ILEPFYSGCSTFLMSPESFVQKPQRWLEAIAQYRGTHTGAPNFAYELCVEKSQSIRDAHL
DLSSWRVAVNGAEPIYYETLEKFVTAFASLGVSWETLSPGYGLAEATLKICSVPHGQAPR
VLALQRLGLEQKRVVELPSSSHEEANKVIGCGRPILGCQIVIVDPETHIPCPPDGIGEIW
VSGASIAQGYWQRSETSFATFQAYLETTNEGPYLRTGDLGFLKDGELFVMGRLKDLIIIR
GRNHYPQDLELTAQNSHPALRLGFAAAFAVTVNHQEQLVLTLEVKRQFVRKLNTEEVVEA
VRRAIAEHHEIEVYAVVLLKTGSIPKTSSGKIQRYACRSGFEQSSLTVIGQWQAPILTEE
TGKETGEEFSSVGSSVLFVEAIRQWLVNWLSEKRQLTLKEINIQESFSNYGLNSLQMVNL
AADLGKLLDKNVSPTLLWDYPSISELADYLGEKTGTSPVQSQTSQSEPSDSAIIEDAIAI
IGLGCRFPNANNINSFWYLLSQGIDAIRRLPSERSASLHRTMPDHHPALWGGFLDLVDQF
DSSFFGIAPREAARMDPQQRLLLEVAWEAFENAGVVPDQLAGSRTGVFVGLSTNDHSHIL
LRNPENLDAYVGTGSANSMVANRLSYLLDLRGPSMTVDTACSSSLVAVHMACQNLKNHES
DLALAAGINLILTPDLTLALSQAQMMSPEGRCKTFDADADGYVRGEGCGVVVLKRLKDAM
DDGDAIYAVIRGSAINQDGRSNGITAPNGLAQQSIIREALAKAQIKPEQISYIEAHGTGT
PLGDPIEVDALKAVFDSNRPVNHPYWVGSVKTNIGHLEAAAGIAGLIKVALCLHHREIPA
HLHLKQVNPHISLDNTSLEFVKTHQPWVTNTDSLYAGVSSFGFGGTNCHVVLQEAPQLSV
TSDVKADLPLLFTLSAKNESSLQALVAHYTQWLTEHPNNSLANLCFTTNTGRSHFSHRLA
VVAKTQEELKIKLQRWNLGEFSKGVTKNVFNERNVTKIAFLFTGQGSQYVGMGQQLWETE
PIFQEAFRQCEALFRPYLSESLLSVIYPQEPRSTLINQTQYTQAALFSFEYALAKLWQAW
GIQPTAVIGHSLGEYVAACIANVFSLEDAVKLVAKRGQLIQNLPANGTMAMVALPADSIV
PYLDSYQQKVVIATRNSPQNTVISGESIAVNQIVEMLRLQGIATKILSVSHAFHSPLMVS
IIEEFAETVKQVTFNVPQIPLISNYTGRVAYSEEICQADYWCNHLLHTVDFQGGLQSLVK
LGVNVCLEIGPKPTLVSMGKQCGFKDVIWLDSVKLGEENWQTLINTLSILYTEGCRVNWA
NLYCDATYQKLHLPTYAFNRKHYPILTVNHHANKEKDESSILPVVQPEEAKILNSPSSQL
LEVLTQQAEALIVQSKILLSR
>A0A063BJC7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Burkholderia sp. lig30|TrEMBL
MKTARPKSGAVIAMTPSHRLTPAIAVAACRAGAIGVLDLGVRKAPADAAAALSALARDAH
DAQRWGVRWDAAGEPPDDLAPLADIVGALAPVPVLVLAGLQADAAARALDAAKRIGSDVL
VEVRDIESARAAQAAGFDGLIVKGHEAGGRVSTHSSFMLLQEFHGQLEIPYWIQGGIGLH
SAAAAVLAGAAGVVLGEQLWLTDEGPFSAAEVPAWAHLDGSETALVGADDVLYRFFSRSG
RSRLRELEVAVAKDAAWEASIAGHLAEPHDGLIAVGQDIAFAAPLGQRYGTVGRIVTAVR
DGIADGIAKAAEQIPLAPDSALARLHGTRFPIAQGPMTRVSDVGAFAKAVADGGALPFLA
LAVLRGPQVREMLTTTQQLIGDAPWGVGILGFIPLELRKAQLDVVREIKPRFAIIAGGRP
SQARELEEAGITTYLHVPAPGLLRSFLADGARRFVFEGSECGGHTGPRTSFILWESAIEI
LANSDIKDPESVQVLFAGGIHDALSAAMVSALAAPLVARGMKVGVLMGTAYLFTHEIVQS
GAIVDTFQQQAVECRETTLLQSGVGIYTRCARTPFCDEFEKVRRELVLASKSDEETLMAL
ELMNIGRLRIASKGIAHNSDPAADQGDSRYVEVDAPTQRREGMYMLGEVARLRSDRCSVA
ELHAAVCAGSETLLRQRRAKPARPAGRPRHEDIAIVGMACLLPRAQGLRDYWQNILNGVD
AIREIGKDRWNVDDVFDPKRGTPDKVYSKWGGFLDDIPFDTQRYGIAPASMGSIEPVQLL
ALEVVRQALADAGFDRRPFPRERTSTIFAVGGMNELGTIFNFRALLPGYLARLTDIPEET
RKRIQNALFDDVLPKWTEDTFPGILGNVIAGRVANRFDLGGANFTVDAACASSLAALDVG
VRQLRDHEADVALVGGVDGTNGPLGFMCFAQTYALSPRGHSRPFDDSADGIAISEGVGAV
VLKRVSDAERDGDRIYAVIRGIGSSSDGRNRSLTAPHPPGQVTALKRAYADGGVDPACVT
LIEAHGTGTALGDRSEIESLNIAFGGASTGTQTCAVGSVKSMIGHTKVAAGLAGLIKAAL
ALRHRVLPPTLGVDKPTSGIDFTRSPFYVNTETRPWLHDGRAYARHCGVSAFGFGGTNFH
TVLAEYTGAYRDSDVVDLNPRDAEIVAFAGATRAEIEAHVQCVLQGLAHPEQIDLAQLAY
AIYREQHVLRRANGGHPCRLTLLVTSVADLKQKLARVLDLLRVHAEITQPPGIYYRETAG
KAGRVCFLFPGQGSQRVNMLRDLVVAMPALHACFADAPGEHDAESDPPIAPFVYPLPVFS
DAERDAQQQALNATRIAQPALGMAGLAAFDVLTSYGLRPDFVAGHSYGEYVALCAAGAIT
RAELLRLSRVRGRLSASAPAGAMAALDVDGEHTVAAIARHDLQVSIANLNAPDQTIVAGT
VDAIDAAVAALSDGSMRVKKLPVSAAFHCDVMAGVRDELGTHLATVAFRSPAIPVYSNTT
GEAYPAESDDVRALLARHIAEPVRFTDEIHALYEAGARVFVECGPGLVLGGLVDRILADK
PHSTLAIDAPGRPGWLQLAQLLTQALSIGLPVKLDTWFAGRGLGEHGLDAVFADAQRRAA
PGPLVWRVNAARARPWNAPAAPAPQPRATPPAARPADAPPAVPAMVASDAARAAEPSPVP
SRPPEPPFTRVRRSVMKADSVSSGGPAMPSAGAQPGGVGYVESELAQIQYSVGRFLDLQC
EQQLTLRHFLDFQAQLIGLPVQHAPEQAARLVSMPMPVPMAAPRVAPPQAGAVAGGAAVV
LSTVPVTPVLPAQLLAQAASVPAQPVETVVDTVVSAPAPAPAAAPAGRAPASSGNGGGVH
ASLASPEAFKADLLRTVSERTGYPPDMLDADAHMEADLGIDSIKRIEIFSGLTTQYNLLG
ERDEEAVIEELSGLKTLNEIIAWYEKLVDEQNGTAQGGMSAKKAQTPPSARNETVESDNG
TAQIDPVQRYAVEPIAERLNDVLDATEYPARHPVLLVGDDTPLAAAFRRALVRGGCRVRQ
VVPGGVTRVIGDGRYEADLSSLESVEQLQALLADSTEPVGAIFNLMGASGGDDAPDRRLH
DGRAFFLLLKVFEKALKASAQDGGGWIVNVTAFDGQFGLSRSRAFPAESAGVLGVAKSVA
REWPATRVKCIDVAPELEPDWLAAQVLAEIRSGQPGVEVGYNAQGRWRLDLKDDGAVPQD
LSKLTLDPDAVVLVTGGAYGITADVTRALAEKYRPRLIVVGRSALPGDEPDEIVDIDDPA
DLKRHLIQDMKRRQGKVTPAEVDRALNRILRDREIRANLAAMRATGAQVEYHSLDVRDRA
AFGGLLDDIYARWGRIDGVLHGAGVISDKLIADKSVESFDAVFDTKVIPALVLESKLRPD
SLKFIVFFSSVTGRFGNVGQCDYSAANEVLNKLANRICHRWPHVHAVAINWGPWDAGMVS
DELRKLYAARSIRPIPAEQGRRHFLEALERGASGAPELVISSSIRQIATLRLGQEKGVSV
K
>A0A2P8AN32|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MH33|TrEMBL
MDWATFAPAYASTRPRPLLADLPEARQALPADDAPADGGAALRDRLLALPREEQDRHLTD
LVRAEAAAVLGHAGPERVKPRRAFKELGFDSLTAVELRNRLNRTTGLSLPTTLVFDHPDP
ANLAAHLRATLVPAADGDAAADPAEVAVRQALATIPLARIREAGLLDLLLTLAGGDDGAP
TPGGADVDLDEMDTDTLIRLALDGSES
>F9U9D3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Thiocapsa marina 5811|TrEMBL
MKHPIEQAFLCLCLNPAELPGGSIALAAARAGHLGVLDLTRCGQTAFTHAIANAPPSAGL
RLRPEQVESAVGAPDLQGRPILITDADLVCAERLIEAARAARATGAAVWIEIPSVVILDA
VRASDLRPEGIIVRGQESPGWCGETGAPVLLQAALASGIGPVLVYGGLGIGGMAACRAAG
AAGVVLDDQLLLLRESPLGPEHRGWLETQSVEASLLLGSSLKAPCRVLQQSRFRQTKPAR
DLAIALEGEDISPEQARAEWRRSIGERLGFGSPETALWPVGQGLGFAERFAREYRTLGRL
LRAIDNAIPRMIETAATQGATLRGSPMAAHLGVADPIVQGPMTRVSDTAEFAEAVAGGGA
LPTLALGVMRPSAISALLERCGERLAGRAWGVGLLGFIEPSLLEAQIECLRRITPSYVVL
AGGRPDQAKTLEAIGLKTFVHVPTPALLERFLGEGVHRLIFEGRECGGHVGPIGSLPLWE
MAVERILAGAGAEIKDLEVLFAGGIHDAASAAMAAVIAAPLVARGAAWGMLMGTAYLYTR
EAVDRGAVVAGFQQAALACRRTATIESAPGHANRCIDTPFVDLFSANRRTLLQDRRSIDE
TREQLDTLLLGRLRIATKGIVRDGERLIEAPSDQQQQDGMYMIGDCAVVKDELTDIARLH
RSVTEDAARWLETRAAEETALRGADAAREGQPSDIAIIGIGMLAPGASDAEELWDVILAA
QPRTREIPAARWDWRLYHDPEGLDPDASVCRWGGFFDPVLFDPLLFGIPPKSVGNIIPAQ
LLMLEMTRRALLDAGYPDGDFDREQTAVIFGAADAAGFTGDAIRARAMAPVLAGPHAAEI
KARTPELADETFAGGLTSVVAGRVANRFDCGGPNLTVDAACASGLTALDIAVQSLESGRT
NLALVGAVDVGQSPGSYTGFTRTGALSPTGTEHAFDASANGFVPSEAAIVMVLKRLADAE
RDGDRIYAVVKAVGASSDGRAMGMTAPRAEGQLRAMRRAYVKAAIPLSSIELYEAHGTGT
RVGDQSEIEAYSGLLKKAGVGAERCTLGSLKSILGHAKTAAGLLGLAKTTLALYHGVLPP
HYGVTNPIPGLTQEGSPLRLLNAPRPWLDRDAHPHRAAVSAFGFGGTNSHVVLEEYRAPG
GPPVPYGAGRWPAELFVFHGPDRDRLRTQLARLQDWLARGAKPSLRALAAASAQAAGDPR
TGWVATAVVPDLERLAEALAGLIGALDEPGRRLPSELGLEQRSTDNADTLAFLCPGQGAQ
YVGMGRALALHAPQARAVFSHVRERLEGKLPLALDDYLFPPSAFSETDRTRLEERLVDTR
VAQPAIGAVSAASVAYLVHLGVIPDMVAGHSFGELTALHAAGVLSLDDFIDLATARGALM
AAVSRPGGMAAVFAEREAVETELGRYPGIVLANHNSDKQVVISGPAPQLEAACAGLADKG
WRVLKLRVSTAFHSPLMAEASDAFARDLSRVVPRPARIAAYSNIDGRRLEGPNVAAHLNS
HLTAPVEFVAMVRQMIGAGARVFVDVGPMDTLAGLLGTMDLPEDIRVVALDPGKQGMPGF
LKGLAALWRAGRPIDLARLFDGRVERIRSIDEVCRDALAPPLRPTSWMVDGHMAWPVSEH
GDGSVETPRWRALKPLYDADSLAREQAERARRTSESANSQPRHSPLPALGEDAGVAGIYQ
AYAETMQAFIASQERIFSALVGSDLPVPASLSQPASIPGAVARPSVSPASAPSRESVPVE
PRPAPASTPQPAPSAPTSLDPKRILMETVSRVTGYPEDMLSLDDDMEAELGIDSLKRLEI
LESFARALPGAGTGNLDVDRLARIRTLRGWLESAESVPPVSMPPGGAQTAGVRPEADGVR
EADRPVRADVSTGNTIDWADAILRVASEVTGYPADMLDLTQDIEADLGIDSLKRIEMADR
LRQEIAGRTDVDIHAFSEDLTRLRHLGEWVDRLCRGTETRLPNAPPNASPAAAPDNSVDA
CPRYVMAAEEQPIETSSDARLSGLFVVTRDRLGVAEELAALLELRGGYAGLVETVDDLED
KIAALRSTYGPVQGIVHLSGLDRGDTFENPVDWADACKRSILDLFRLLQAVRGDFERPDR
TKTRWILSASALGGRFGRDTTLLAGSPVAAAPLGILRSLEHEWPSLHTRCLDFERDRPPL
AVADAIVNELIFADRAPEVGYLQGERWSYSPRPAPLDHTEGDAAELPPDAVILATGGARG
ITASLVGALARPGMRVVLIGRQALEDVLASDAGEEKTPAEIRARLIQADRSAGRSRPPAA
IEREVGVVLRHQEAVATLRRLRASGIQVEYHACDVRDSQAFGALIESLQARLGRIDLLLH
GAGVIEDRLLVDKTPDSIARVFETKANSAHTLMARLDPERLGTLVLFASTAGRFGNRGQS
DYAAANETLNRLAWMMRAKWPRTRVLAINWGPWTGVGMADAKVQERFARQGIPVITPEAG
ARFLIAELAAGASEVCEVIAGDGPWGIAGQAQRATSDLEIERRSGERVHV
>Q0RIF6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia alni (strain ACN14a)|TrEMBL
MSNEEMSNEERLRGYLKRATNELLATRAKLENVELAAREPLAIVSMACRYPGGVRTPDQL
WDLVSAQTDAVTPFPTDRGWPLDELIDPAGDTPGTSYAGEGGFLHDAADFDADLFGISPR
EALTIDPQQRLLLQTAWEALERGGLDPRSLSGAPVGVFVGLMYSDYGSRHSRAPEGFEGF
IGTGSAGSIASGRLAYTFGFEGPAVTVDTACSSSLVALHYGAQAIRRGECSLALVGGVTV
MATPATFIEFSRQRGLSPDGRCKAYAAGADGTGWGEGVGLVLLERLSDARRNGHPVVAVL
RGSAINSDGASTQLSAPNGTAQQRVIRAALSDAALAASEVDAIEGHGTGTGLGDPIEVNA
LLATYGRAHTRDDPAWLGSLKSNIGHTQAAAGIGGVIKMALAMRHGRLPATLHVDAPTPH
VDWDSSAVSLLTRSIAWPSRERPRRAAVSSFGISGTNAHVILEQAPAPDGGQAVAEPAGA
GSEPAGAGSEPAASGPRIDPDAPGPQQPGPVAWVVSGHTAEALDAQLGRLRGFLADHPEA
DPADVAHTLAHGRAALEHRAVAVGTSRVELDEVLDALEHDLPTTRGARGEAITAGRPVFV
FPGQGSQWVGMAAGLLETSEPFRTELDRCARALAPHVDWDLREVLTGDGAALERVDVVQP
ALFAVMVSLAAAWRALGVEPAAVVGHSQGEIAAAYVAGALELADAAELVAVRSRALVEIA
GTGAMASIDLPESAVRARLLPGIDIAALNGPNATVVAGQPAAVAALVEGCTAQGVRARLI
PVDYASHSAAVEPLRDRLLAAFAGVRPRSAGVEFLSTVTASRIDTAELDAAYWYRNLREP
VRLAEAVAALAEAGHRVFLEVSPHPVLVAPVREVLDGLAEPARALATLRRDHGGVEQLLT
AAGALFAAGTPVDWGTAAAGRLTDLPTYAFQESRHWLDTNAVPTAGPGIAASGHPVLGIV
VDQASGVLLTGRLPGGPGWARQHRLGERTLLSGAALAELALAAGDWLGVPALEELVLLAP
VDMPDGPVEAQVSVGEDSRFTIHTRVGGQSPGATWRRHATGSLAASDESGGAVATGPASW
PPPGAEAIDLPAAYAALSGFGVHYGPALRAVRSAWRAGGEVFADLALPEGEGVHGYLLHP
VLLDAAVQVAFLDRATGPRAPTDPAVVPFTWTDVHLYATGARELRVRLTPTGADAFALAA
FAVDGSPVLTVAGLTLRAVDGAGGAGSTTTGTTTGTGVDVVAPARTRARRQRARVGGRSA
AAKLTPDALAGLAGEERVEALLGAVRAAVAGVLGHRSAEVVRPDRTFRDLGLDSLTAVEM
RDHLSRAVGRRLPATLVFDFPTPRDLARHLAAEPGAVAGAGARRARDADDPIAIVSMACR
YPGGVVTPEDLWQLVSSGTDAIGEFPADRGWDLASLFDDDPDTPGTSYTRRGGFLGDVAG
FDAEFFAMNPREARATDPQQRLLLETSWEAVQRAGIDPTRLRGSRTGVYVGLIYTEYGAR
AAGNPAEHGGYLSTGSAGSVASGRISYALGLRGPAVTVDTACSSSLVALHFARQALHNGE
CDLALVGGATLMATPSIFVEFSRQRGLSPDGRCRAFADAADGTGFSEGVGMLVVERLSDA
RRNGHPVLAVVRGSAINSDGASNGLTAPNGPAQESVIAQALADAGLSAVDVDVVEAHGTG
TTLGDPVEARAVLATYGADRGSAPPLWLGSLKSNIGHTQAAAGVGGIIKMVQALENRVLP
RTLHVDAPSRHVEWGRGAVALLTEDVPWPDGERTRRFGVSAFGMSGTNAHVIIEEPSRAP
AATVDAAAAGGSGPGGPPVPLVLSAKSPASLRGEARRLHAYLRSHPGQSLAGVAAELVHT
RPQFDHRAVVVARDHGEAIAGLTALAQAEPAAGVVSGHSDGEREAVFLYPGQGAQWTEMA
RELLASSPAFAARIAECAAALDPVTGWSLLERLRGDGGEVDAAGPVQSVDVVQPLLWAVM
TGLTAVWESVGVSPAAVIGHSQGEIAAAGAAGALSLADSAAVAALRSRALAAIAGRGAML
SVSAPRDRVDATLAAVTVGALSVAALNGPNSTVLAGTAEAIEAARELFERDGFRARPIDV
DYASHSAQVEVLRDELLRVLPRVEEHDWSGVDYFSTVTGARLDPQSADDFGQPEYWYRNL
RQPVLLQDAVRAAIDAGYRTFIEISPHPVLTVGLQDIVDEVPDAAATALGTLRRGDGGLD
RFLLSAAEAWVAGVAVDWRAQVGPRHPGLPVLPTYAFDRGQHWLDAAPVGPPAAGSVPLA
HPLLTSALRPAHGPELLLLGRLGLASQPWLSDHAVAGTVLVPGALFAELAASAGDVVEAG
RVDELVLRTPLVLADGQDVEIQVTLGAPAADGAREVGIHSRAVPAPGSLGASWTEHASGT
LTPAAAADLGALPGAWPPPGAQPLATDRVYDELAAAGYHYGPAFRGLAAAWRLGDTVLAE
IAVTGPAGFVVAPTVLDAALHAVGLAGLGAVDGAVRLPFVWRGLRRFAPAPPAGRLRIRL
RRTGADAVGVHLFAPDGTPVAAVDEVALRTVDAGELDAVRPQDVAGLAGLLYRLGWEPVD
GAHRARPARLWTVGSGGDQPDLAAALGALDEGRDRPDALVLLLPAATGPVPQATRTALAG
VLDDLRRLLADERLREAVFVVLTRDAVAAVPGDRVGALAQAPIWGLVRSVQAEEPGRIVL
VDTDRPDPSTDLLRDAVAGGEPQVALRDGVLLAARLGGWRPALVAPAAGDWRLARGEGGT
VDDLVLLGQPRPVLEPGQVRVAIRASGLNFRDAMLALGLYPGEAELGTEGAGIVVETGAD
VTGIEPGDAVMGLISGGIGPVAVTDHRLLVPIPAGLSFARAAAIPAVYLTAYYALRDLAR
VQPGESLLVHSAAGGVGGAAIQLARHWGVTVYGTASPAKWPFLATLGLAADHLANSREVA
FAEHIRLATGGRGVDVVLNSLSGAFVDASLSLLGPGGRFVEMGKTDVRDPAQIQARHGVE
YRAFDLMEAGEDRIGQMLAELADLLGAGVLTPPPVTAWAAGRAPEALRHLSQARHVGKIV
LRLSRPLDPEGTVLITGAPGGVGSLVARHLVAAHGARHLLLVSRRGPASPGADELGAQLT
ELGARVTFAAADVADADAVRRVLAGIDVEHPLTAVLHAAGVLRDATLATLTEVGLDAVLR
PKVDGAWHLHQLTRDVDLAAFVLFSSAAGVVGSPGQAAYAAANVFLDALAVARSRDGLAA
TSVAWGLWRSDSAMTGSLSATDQARMARAGVLPLSAAHSLALLDAALGADVPALVAVRLD
PARLVAGADLPAPLRSLARPAQAAARPQPVVADLATQLADAEPHRRRELVGQFVVSNVRA
VLGHTAGDAGEGDGPGDRSFKELGFDSLTAVELRNRLGRASGLRLPATIVFDHPNPAALA
GYLLDRLVPAQPTPAATTPPATNPPATTPVQAGPAVPPPVVEITVSSPASQAEELFRFID
AELRP
>F9U9E1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Thiocapsa marina 5811|TrEMBL
MRLNLGNRIYYRDAGGLEEPGRVAVLFPGFGHRDTGLARQLCGLSPAVDAWYGSVAGPRP
FGLASGDSGSELAGMLDDVLMADLAMWVLLRDLGLSCDLLVGHSFGEHAALVASGMVPSL
ADLSPLFASVASLDAEGDPLGMLAITEAAVDLIAPEMQRDPPSVFMALDNCRQQKVFWGQ
PEVLGRVEAQVKAQGLLAYRLAGLACPVHTPAFPVGGEQLRRDYAALALSAPRIPVWSCS
RLRPLPEERTAATEVLAAQWHEPVRFRESILALFDAGFRTFVEVGPGERLSGFVRETLRG
KGVSAVPTHREGHPPLQTIHVALAQLYLLGQAIAPDRLSPRPSVSEERFDGRGITSSGPP
ETRGESGPPPAVQQPASTDRQRFRDLVEVIQGEVAGLLDLADPESLDSETGFFDLGLGSL
GCVELSERLGRVLGRSLPQTLAFDYPDITRLARALASAPGTSPECAGSDAGRATAASESA
SENEPIAIVGIGCRFPGGVDSPDAFWQLLREGRDAISEVPPERWDPGVYEGWIDADQREA
ARFGGFLADALGFDADFFGISPREAKTLDPQQRMLLEVSWESLEDACIDPKGLGGSRTGV
FVGISSADYVQRLSPTQRLEVGGYLATGNAPSTAAGRIAFALGLNGPAMAVDTACSSSLV
AVHLACASLRRGESDLALAGGVNLMLNPETTVFLANAHALSRSGRCRTFDAGADGYVRAE
GCGVVVLKRLSDALAAGDAVVAVVLGSAVNHDGRTSGLTVPSGPAQNALIRDCLHSAGVE
PSEVGYLEAHGTGTPLGDPIELQALGEVFRSTRAVPLRLGSVKSNIGHLEAAAGIAGLIK
AALQLRRRRLVPSLHFRTPNPRSNWASLPFEVNRDDRDWDSVGRRIAGVSSFGISGTNAH
VILAEAQSTRSAIEQNAESDGADTGRAHLLVLSARTPEALRTAALRMVDRLEESPVDRSM
DPGAVEPGAFTTLVGCPASTLVDCASLVHPTPLVHPTPLVQPTAPIGDVAGFIGDAVEPL
SALCRTSWLGRHHWRYRIGVVARSRLEARDRLRERMASAAVDRAGAEARAPRVAFLFTGQ
GSHEPGMGRELYATEPVFRRAFDRCCEGLAPDLEAPLAEVVLDPRDRRLEQTAWAQPGLF
ALEYALVETWRSRGIVPDVVMGHSLGEYVAACVAGVMSLEDALRLVAVRARLMQSLPAGG
GMLSVAASPEGLESVVSLASLGLDLAAVNGPASLVVAGPVGALDRAERRLMEAGIGCRRL
PVSHAFHSRLVEPILAEFGRYVAACRLSEPRIEMVSNLTGERVRHEVTDPAYWVDHLRRT
VRFEAGMRTLSTLGCDAYVEIGPKPVLTALGRESADDARGVLWLASMQPPVDPSLTLLNA
LGQLYERGADPEWTGLEPAAAKRPRARLPTTPFERRSFWIEIAEGRHDAVAPSDAPPRLP
GLLLNLPGNTGALRFEARTGVGLTPELDGYPALAERALPPGLLLYAALRAARRAAPGIEM
WLEALRLVDVQRLADPCVILHTLVKTPNADPGVVEIYGRAEGVEDAPWSLLIQARLRAVS
GSPQPEPRPMSGRTRDADESLLARLRSAHSAIEKAAFYRAGEQLGFRYGPDLQVLREIRL
GMHAASAVLDLQTGGGVDPSPLPDLPLAAIEGGLQLLGGLDAGATPPRVRQLRAIDRIDV
AAPLPREVLVLVWRAEDHASATIRLLDARSFLLCAELSGIQSDAMEITRVSTAEGEIRDR
LERVPREEWPPLIVGFVNRIAGLIIDGSPDYRIDPSRPLTELGLDSLMALRIAIELKADL
GVEIPVSQIVSGATIETLAAVSVEQVMDGDLTTEVSQRLDGFFQEGEL
>K9ZE13|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Anabaena cylindrica (strain ATCC 27899 / PCC 7122)|TrEMBL
MNVSFPNLQFSSLVELLRHRALHQPDRLAFVFLQDGEIETASLTYQELDTQVRAIAAHLQ
SIGASGERALLLYPSGLEFITAFFGCLYAGVVAVPAYPPKQNQKLTRLQSIITDAQAKVA
LTTKSLFENIQGRFTQDPELTKIEVLATDEITQELATNWQNPKVDSNILAFLQYTSGSTG
TPKGVMVSHGNLLQNLEYIKQAFELTPDTVSVSWLPGFHDMGLIDGHLQPIYTGFKCILM
PPASFVQRPIRWLQVISRYQANHSGGPNFGYDLCASSKLTPEQIESLDLSHWHSAYSGSE
PVRKETMERFATKFKPAGFQTKFFYPCYGLAESTLMVSGGNIQDEPIYFQVEAEALEQNR
IVLANKNTKNIRYLVGCGHSWLDTQILIVNPETMESCAANEVGEIWVSGYSVAQGYWQRP
ETTAQTFQACLADEQGPFLRTGDFGFLHNGEVFVTGRVKDMIIIRGRNHYPQDIEATAVK
SHPALRIGFAAAFAVEVDGEEQLVVISEVERTAIRKLNIDEVVKTIRQAVTEEHELQVYA
VVLLKPASIPKTSSGKIQRHACRTKFLEGNLDVVDMWQSSQTPTAKIEPPRPLQTLNKQA
ETIQAWLVDKVAQQLKIAPQVIDVQEPFARYGVDSLAAMMLSTELEDWLQLSLSPTLVYD
YPSIATLAAHLAVVVENSQPEEVEETSQEKEPQFPDAIAVIGIGCRFPGAKNPEAFWQLL
QNGTDAIVEVPSDRWDIHQVYDAQPATPGKMNTSWGGFLEDVDQFDAAFFGISPREAESI
DPQQRLVLEVSWEAIENAGIAPQKLKGSQTGVFIGISTNDYARLQFNHPSGTDAYFGTSS
AFSIAANRLSYLLDLRGPSWIVDTACSSSLVAVHQACQSLLQGESKLALAGGVNLILTPE
LTITFSQAQMMAADGHCKTFDANANGYVRGEGCGMVVLKRLSDAQKDGDNILGVIRGSAV
NQDGRSNGLTAPNGPSQQAVVRQALAKAQVQPAQISYVETHGTGTPLGDPIEVNSLKEVL
TQGRTPSCICWIGSVKTNIGHLEAASGIASLIKVVLSLQHQEIPPHLHLQQLNPHIKIKD
TGLSIPTQRQTWTKGKEQRFAGVSAFGFGGTNAHLILEEAPQVSHKEQEFERPQHLLTLS
AKSQTALQELAQKYEQFLATNSQVALADVCFTSNTGRSHFEHRLAVVTESTTQLSEQLRT
FANSQPSSVLLSQPETSKHRKIAFLFTGQGSQYPGMGRQLYETQPVFRRTLERCEQILRP
YLEQPLLSVIYPESDSNSVLNETAYTQPALFALEYALFELWKSWGIVPDIVIGHSVGEYA
AACAAGVFSLEDGLKLIAHRAKLMQSLPPNGMMAAVFTNEQRVAEAIASYPEVSIATVNS
PKQTVISGTKAAIQEILQQLESQKISAKALRVSHAFHSPLMNPMLEAFTEIAASVQFNAP
SIPLVSNLTGEILSHQDIPDANYWCHHIREAVRFSAGMETLHRQGYELFLEIGPNATLSN
LGKQCLPQGTGTWLTSLTKEDNWQSILKSLATLYTQGVDVDWCGFDQDFTRHKLALPTYP
FQRQRFWIQTDERNQTKLGTQPEPQLTSPPLDQPTSQPYFYSWQWQPQQLVEPKEILSGV
VLIFKDAQMVGKNLEKLFDPAKYTVYFVTAGQKFQQNTEWHFTINPASPSDYEQLIQTLK
QQGLTITAIIHLWNYHQAAISRLPINAHDALLQEGMYSVLYLGQALIKHDANSAISFLLL
TQGAYVTSAHEHLQGLHQAMGATLAQTLTQEHSNIQTKVVDITPASESSETLAQILYKEL
QTQPDSEGIVVLRQGQRLIRTLESMEISASQEYQPVLTPGDTWLITGGVSDVAAEIAQGM
VSRAPINLVLTGRHPLPSKTEWYLHQGDDSTSKRIRIIQNLEKLGATVLYYAVDVTDAEG
MQQLMVNIRERFGHLHGVIHAAGVQDRTRFKLAQKTPETVASVLAPKVEGTMILDHLTQD
EPLKCFAVISSAAASKAEWSANLGDYAAANIFLDNYATYRSQRGAPGHSLAVNFSLWRDK
GMVKIGGQKLVMWAQVKGLKLLETDMAVNAFITSLSSDSSVIHIIDLLELETTQVSAEKE
NISAPPPNMRRLVRETISQYLAVPQHEVEGYRSFPELGLDSLGAVEAIKQLSLTLKQQLS
PTLFFEYGTPDDLADHLEKQYGASIVSSAVTPINKPKVEPPVKHLMAQPSNFKSMEVKQQ
DIAIIGMGCKIPGADNLEQYWQLLSEKRSVIQEVPSDRWSVADYYEENGTTPYKTYCKRG
GFIENPFDFDPMFFGISPREATVMDPQQRVFLEVAWQALQQAGYGSRYRTKDIAVFVGGE
QINYIEHFFNYQYYSVLQQRLQNSALFKRLSTAEHKDLLDMLSEVLQPSEMLPEATAGNE
LNQIAARLSHCLDLIGPSMEVSTACSSSLVALHLACESIRAGDTSMAIAGGINLNLSPTP
FTFLSRVQALSPTGECYPFDSRANGMVVGEGTGVVILKPLRKALEDGDYIHAVIKGSAIN
NDGHSQGITAPKPEGQAETIRRAYTKFGIDPETISYIETHGTGTALGDPVEVEGMTKAFR
DFTNLKSFCGIGSVKSSIGHLLAGSGIVSLIKVVLAMQHGKIPATVGFEQPNPHINFDNT
PFYVVGGQGKPWSSNGELLRAGVNGFGFGGTNCHVIVEQSPLSSAIKSPEPTSSLSPHLL
CLTARNQKVLKEVVQQLHEHIIKHPEQELSEICFTLSNSQRELAYKTALVVNDRQHLLDS
LNAICLDQINSNVQIDRSNPQKATPTYLVLDNSSNLTPEDAKLLSDRFPEFRKAYADCEF
LWRHTVNSDFSQKAHTFAAQYAVCNLLMSLQLQPTALLAEGIGILVGACLTATLSLKQAI
VLLANLEEKQINKSVEEPRLEATSLTVWTCPIVTSSEVLKSSSNLTSEKLQSLLQVSGAL
KIADCQDVCSEHGAYLYLGDSASIKQQLGITDELQVWIQAQKKSTIIDCLLTMISRLYVA
GVQFNSVALFPKGLRKVLLPTYPFERKTYKAPIYYSQLENLHDIQQALNMDCLVLVEQLP
PLSHEQRYSSYKALIEKFGFSYPSLDNLHN
>A0A086JT20|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii p89|TrEMBL
MTPDELHTYVSNVVLDTARQVLGTSELPALDSPLQELGIDSLGAVELRNSLSQRLGVKLS
ATTLFDYPTIRAIIDYIVNQVSGEASAAKATSGALVSAGLAAGRNSPIAVVGYSCRLPQG
SETPDKLWEMLRRAQDCVVEVPLTRFDVDMFYDSDIDAKGKMYVRKACFMDDADMFDNSF
FNISAAEVTYMDPQQRVMLEVAYDAFYSAAYSREHLIGKNYGVWIGCCNSDWHFLEQQSN
PDKSSSYSGPGGSGCLVSNRLSYVFGLKGPSMTIDTACSSSLVAADCGAQAMRFGYCDGA
LIGGVNLMLSPQLFLAFCKARMLSPDCRCATFDEKANGYVRGEGAGAIMLRHLADAQREG
KRILGIVRGTAVNHDGRSASLTAPNGPAQQDVIRSALQIGGVDPLDVALVESHGTGTALG
DPIEMGAIKAVYGAGRSADSPLVVGALKSYIGHLEGSSGIAGILKVLLCLRHHEVPPNLH
FDTPNPHMDLSDFHVVLPKKQMKLQPAQKSSTILGSVSSFGFGGANAHVVFEEYPEPTMA
TDVGGERRSTEAAESAGKKRLAFLFTGQGSQYPNMCKQLYEEEPVFRSHMDACFTVLEGK
LDVKLRDVIYPTAENDVEMLNLLNQTGYSQPAIFCVEYALAQLMISKGFSPSVVMGHSLG
EYAAAAIAGVMDWKDALLLVHERASIMQHIDPNDGVMYACRASEQDAQAAVEKALGEKAV
AVTVSAINGPRSIVLAGTQPDVLAVLKAMDMQSRAKQLTVSHAFHCPLVGEAAALLLPKV
ESVKLSNPNEGITFISTVTGKAVGAGELTKPEYWATHITKPVQFLQGMRAAVTSGEAGIF
IEIGPRPTLVNMGQQCVPRNDYTWVAPVDPKDSNRNSFPQALEKITSNMVCTYTWKRHAF
PWTVVVHPFVDKFVPDQDETKATSQKLLTPAVGELLHDHVVNGTAMMPGVGFLEAMAAGG
FMMVDGKLPSTVVALRDCEFERPMLIPKIDPSTGEFTQAAKLMITVNNKDITLKSIMDGE
EEEIFHSRCTFSLCPATSLPTEPADLLTSLQGRITTPVPITTLYETLQSVGLQYGARFQS
IRECYAAASDEVLAKLRPKLPLHSFERNFRIHPVLLDGALQTAAVLFAEMGHKRPLVPVG
VKRALLARVPAGSEVWSHVVVKSKDLRSATMDVTLFSTKGTILGQLVDVAVRAFDAVAGA
QIPKGLLWEVSWVPKAKAPVEDGVDTVENEASETITPTAKLAVKPTGKVEGLARQPAVNG
QPKWLLLKTPSSMLEGLQKALQGTPSAFVKELDEKHPNNAISSKIHNSEWDAIIYLGALS
AAASSTTCVADALLLANTLGNTAAEKPLPNVLFVTQGQHFIRECGDVPTTAVPTQTGLYG
FCRSAQLELENIIGRPVYLGTLDFAAKDPTLDDPAAFVSALQRVLAEADPTGAAGTCEPH
TVIRGGKEMVPRLVKSSIECRGAVELHMSDRGALSMLKLRPMPKSARVPPPRDCVEIRVR
AVGLNFRDVLNVMGLYPGDPGPPGADCAGTVVAVGEGVEHLRVGDAVFGIAQGALKTFVT
TSAHLVRPLPGRLTFEQAAALPVVASTVEYALHDVAKVKKGDKVLIHAVTGGVGLAAVQF
CKRVGAEIYGTCSGGKKEEFARSVGVKYITSSRDPKKFAEDMCEFLGNGKHKIDVVLNCL
IENYIPETLKFLAPNGRFVELGKRGIWTREQMGTVRPDVLYETVAIDTMMEEDPVWFGGM
LDRIRNLVDGSMLQPLPLHTFEMTDSSEGGVAAFRFLQRAQHIGKVVIRLSSALEVKNFT
TNSRQETENEDSGERHTLSPATAVGKPLSQSVADQMHKTYIITGGTGGLGLVVAQWLIEE
GAHNIVLLSRRGEPPSSVKAGDPVWKYLCGEEQPNCISVATLKCDVSQKDDLLRVFKEIE
SRGLPPVAGIFHAAGVTADAALASQTADSVDQVYLPKAIGAWNLHDACEALGLNKSLEVF
MMFSSVAALLGNFGQANYSAANACLDALAMYRQSLGLCGQSIQWGPWIEQGMAAQLTQHL
EKVGMRGITNELGLRVLGDVMMHPTVAVVGAQSLQWRKFLRRYAFEMPSFFSLVPMAGAG
SSEASVNLATITKEDLCELISSLAQAVSGAAEKPAVDTPLMDLGLDSLGAVEFRNSVADK
VGVKLPQNLMFENPSISSISDYILDKAAGKHGESGVTGANGGSGEGSDIPALDTPLDQWL
MSVLEPAERFALYIDSFASEYGTLQKMAAEEDIITALEDLGVEDGGDFERLHVAWDDLCN
QINTAKRMAAKDIRPSSTAVSVSDHPKPRMPHPMEDVDTLLASLDFDVSTLRPATAPDKV
KNVLLTGVTGFVGRVQLASLMQLKQRPDLRVYCLVRARNADHALSRIREATKEAKCWQET
FVSRIVPVTGDFTQPLLGLSSEEFQELARKIDIVYHTGGDVNLLSNYGRLRATNVLSVKA
IIDLCTTYKVKPLHFASTLGQFPAFFAMFTGHFSGESIREDSTPDVSQMENFYPPSRQGY
PWSKWAAERVLEGARKRGLPVAIYRLPNTYVAYKTGYTNKTDYATALMIASIQEGVFPIG
AATAPLTPVDTICDMLVEASFLEKPKHWVYHLFDPRLVTRADLEQWSQELGISYVGVKVD
EFLEAIKKRGPESPVFKFVPLMQHWRRFWFDPEERTESFPISNEHIFEDLPHMRWPSLRE
VFKNSLLYSVRMGFFPKNSKSIILDPQVALNEARRICGLQLMGREGEDFFLHPWRVLQES
ARRECDLLFGGQLAVYRTVRHYFMNVMYLADAQAKCPEIEKQEIQAPLIIVGLNRTGTTF
LQNLMSTDPSNRSLRYCEMIAPYGPDGNYRPKGLPNTEESWKKDPRIPFAQEILDSQLGL
SEEWMAIHTQRAELPEEDFVIFEHCGRCYSICTEFSVPSYREWLASDNYKETRKAYSFHK
RFLQHLQWQRPAKRWLLKMPFHLFTLEALFETYPDAKIIFMHRDPKETMGSWASLVKHAQ
QSLMDNVDPSALGREELRAMSTMINRALAFRRSHPELGPRFLDVQYQDLVNNPIGVVKSI
YKHFGIPLTLAAQTGIASFCNENRKHRDKLTKHMYSLKDVDLTDGMVQEAFKEYYDSGLC
KYLSSAR
>A0A4P7C8K9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Saccharomonospora xinjiangensis|TrEMBL
MTEETKLREYLKRAINDARETRARLREREDADHEPIAIVGMACRFPGGVASPGDLWRLVL
TGGDGVSAFPADRGWDIEALFHPDPDHPGTTYVREGGFLHEAGEFDPGFFGISPREALAM
DPQQRLLLETSWEAVERAGIDPVSLRGSRTGVFAGISSMDYGAALAGTPRGRDGTLSMST
GGSLVSGRVAYTLGLEGPALTVDTACSSSLVALHLAAKALRSGECALALAGGVTVMSMPD
PFVTFSRQRGLARDGRCKPFAAAADGFTLAEGVGVLLVEKLSVARELGHPVLAVVRGSAV
NSDGASSGFSAPNGPAQENVIRQALANARLEPSEVDVVEAHGTGTTLGDPIEAHALLATY
GARRERPLWLGSVKSNIAHTQAAAGVAGVIKMVESLRHGVLPPSLHVDEPSPHVDWDLGE
VELLTEAREWPDLDRPRRAGVSSFGISGTNAHVILEQAPARERDETTGTAVPAGTGDGPV
PWLLSGKTAEALRAQAGKLVSHAEDQPESRLADIGFSLATARTALEHRAVVVGADRAELI
AGLRSLAEGEPGANVVRGTVAADDRVVFVFPGQGSQWPGMASELMREAPVFADRLAECSR
ALDEYLDFSVIDVLRGEQGAPGLDRVDVVQPVLFAVLVSLARLWRSYGVEPAAVIGHSQG
EIAAACVAGALSLPDAARVVALRSRLIAEELSGKGGMALAGSTADDVRARIARWEGRISV
AATNSPASVVVSGEPAALDEFLAECRRDGVTAKRISVDYASHSAQVEQIRDRLVAALADL
APVESTIPFFSTVTGDWLDTTRLDADYWYTNLRGTVGFEPAVAALAERGFGIFVELSPHP
VLAMAVQEIDEDAVAVGTLRRNEGGLTRFLLSLGEVCAAGVSPEWTAVFGDSATVVDLPT
YAFQHRRFWPEKAQGQTGDVASVGLAATGHPLAGAVVPLPGTDGFLLTGALSVRTHPWLA
QHTVLDTVILPGTAFLDLAVRAGEEAGLGRVEELTLEAPLVLPGEATVQVQVEVGAPDDA
GSRPLSARSRLEGEPWTRHATGTLAAATPVRDDVVAGPQDGTELDIGEIYARLDEAGIAY
GPLFRGLRRAWLDDDAVIADVCLPDDADPAGYGVHPALLDSALHPADPVLDREDDGARLP
FSWRGVSVHRTGARALRVRVSSSGPDTLSLAAYDESGEPVLTAESLVLRPVSGDGLGSAR
FRNSLFRPDWEPVTEATAGTSTDLVAIPCPDTGELRETLTEVVTLLRSWLADDRPERLAL
VTTGAVAVGEERAPANPDQAAVWGLVRSAQSEHPGRFVLIDVDRPGAPLPDGSEPQYAVR
DGRYYAPRLVRAAANETGEPVFDPEGTVLITGGSGTLAGLVARHLVTAHGVRRIVLASRS
GGADPVTDGLPAEIRPVVCDVADRESVALLLDSLPARHPLTGVVHTAGVLDDATVDSLDA
DRIDRVLRPKVDGARVLDELTSGLDLSAFVLFSSGATTFGAPGQGNYAAANAWLDALAAH
RRARGLAGVSLAWGLWAERSGLTKGLSDHDVARMARSGSEAMATDDALALFDAGLGSAEP
VLVPVHLDPRSLREQAASGTLPALLRGLISMPASTSASAGSSAVAEDLATLPGPERLRRL
LALVRTHAATVLGHDSSDAILPEAALKELGFDSLTAVELRNRLSTATGLRLRATLVFDHP
TPVALAAHLDSFFCEERSGTDTILAELDGIEARLAELDDAGSERVVRRLEALAARRNGPR
DEGVDMRLDSATDDEMFAFIDRELGV
>A0A2K8RGB3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MENEEKLRHYLKEVTKDLRQTRQRLEDIEAKSREPIAIIGMSCRFPGGIATPEALWDLVR
EGGDAVSDFPTDRGWDTEGLYDPAGGSGKSVTRYGGFLHGIADFDAALFGISPREAIAMD
PQQRLMLETSWEAFERAGVHRDAVRGSRTGVFIGTNGQDYATLLSAARDEVQGHLGTGSA
ASVLSGRVAYTFGLEGPTVTVDTACSSSLIALHLAVQALRNGECELALAGGVTVMTTTNT
FVELSKQGGLAPDGRSKAFAAAADGTGWGEGAGVLLVERLSDAERHGHPVLAVVRGTAAN
QDGASNGLTAPNGPAQRRVIRAALSNAQLSTGDVDVVEAHGTGTRLGDPIEAQALLDTYG
QDRERPLWLGSVKSNLGHAQAAAGVAGVIKMVLAMRHGVLPRTLHVDEPTPHVDWSAGAI
RLLTERTPWPETDRPRRAGVSAFGVSGTNAHVIVEQAPETEPIEPSRIEPVAVPWVLSGQ
GEAGLRAFAARLADVATEAHPGDLGWTLATTRSALSHRAVVIGSTPADLRSGLAAVAAGE
PAPNVVEGVAGPDTGVVFVFPGQGSQWAGMAVELLDTSPAFARRFAECARVLEAHLDWSI
EDVVRSVPGAPSLDLIEVVQPVLFTMMVSLAELWSSYGITPSAVVGHSQGEIAAACVAGA
LSLEDAAKVVVLRSRLFAETLVGNGAIASVALPAEQLATRIEPWGERLAVAGVNGPAAAT
VAGDPQSLEEFVAACVADGVRARVVPATVASHGPQVEPLRERLLALLADVAPRQSTVPFY
STVTGGLLDTTELDADYWFWNARKSIDFLGALHALFADGHRVFVESSTHPALTMGIQDTA
DASGESVVVTGSLRRGEGGLAQFCSAVARLHVHGVRVDWPAAFGAARRVELPTYPFQRER
YWLTPRPGHGDASALGLGALDHPLLGATAVLPESGGCLLTGRLSLATHPWLADHALSGVV
LFPGAGFVELVLQAGLWLGCGVVEELTLEGPLVFSERGGVEVQVVVGGVGEGGVGGGGCR
SVSVFSCRGGEWVRHAVGVLGVGVGVVSGVEVWPPVGAVRVGVEGVYEGLAERGYVYGPV
FQGLRDAWRRGDEVFVEVAVPAEARGDAARCAIHPALLDAALHGVRFGDFVSDDDQAYVP
FSWTGVTLNAVGATALRVTLSPAGRDAIALRATDTTGAPVLSARSLALRPLSAQQLDDTR
GSRTDALHRVEWVDASGAVAAGGEVASRTEVVRVVSEGADVVGEAYGHVLGVLERVRAWV
GDEDLAGERLVVVTRGAVDAGGGVEDVAGAAVWGLVRSAQSENPGRLVLVDTDDVEGVGG
VLPGVLALGEEQVVVRSGVVRVPRLGRVRAPGEVSGGFGSGAVLVTGGTGVLGGVVSRHL
VARHGVSRLVLLSRRGAEAEGAAELRAELEGAGAEVVIAACDAADGEALAGVLSGLPEGF
ALSGVVHAAGVLDDGLLTSLTRERVEPVLRAKVDAAWNLHELTAGMNLSALVFFSSAAGV
LGNAGQSSYAAANGFLDALAAHRRARGLPAVSIAWGFWEERSELTKHLSADDLARAHAVP
MPISQALDLFDAALAADEAMVLAAPLDPRAWSDADNPPAVLRDLVRPRIRRAAEAADASG
SASALEHRLAAVDRSEWDQVVRELVRNHIAAVLRHASAESVDTSRTFQEIGFDSLTAVEL
RNRISAATGVRLPATAVFDYPTPRALADHLLAEVLGKDIGAAAATPAGAALVADDPIVIV
GMSCRYPGGITSPEALWDLVRSGGDAISALPTDRGWDLDGLYDPDPDRPGRSYARSGGFV
YDAAEFDAAFFGISPREAAAMDPQQRLLLETSWEAFERAGIPATSVKGERIGVFTGVMHH
DYLTRLSTTPDGVEGYLGTGAAAGVASGRVAYTFGLEGPAVTVDTACSSSLVALHLAIQA
LRLGECSLALAGGVTVMSTPTVFVEFSRQRGLASDGKCKAFAGAADGTGFAEGIGMLLVE
RLSDARRNGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLSAVDVDVVE
AHGTGTTLGDPIEAQALLATYGQGRDVDRPLLLGSIKSNIGHTQAAAGVAGVIKMVMAMG
HGELPQTLHIDEPTPHVDWSTGRVELLSEHTEWPEAGRPRRAGVSSFGISGTNAHLILEQ
APLPTAGERTGDTEPGDAKSGDVRPGDVRPDDVRPRVAGPGAVVPWILSGRDRRALRAQA
ERLRAHVASHPDLSVADIGFSLLTSRAVLEHRAVVLGGDHAELSAGLTALAQDEPAPGVV
EALDAAEPGRKVVFVFPGQGSQWAGMALELLESAPVFARRMGECAEALAPLVEWSLPDVL
ADERALGRVDVVQPVLWAVMVSLAELWRSYGVAPSAVVGHSQGEIAAACVAGGLSLADGA
RVVVLRGKALLALSGRGGMVSVPVPADRLRDRPGVSIAAVNGPSSTVVSGGDEALDAVLA
EFPAAKRIPVDYASHSPQIDGIRDELLKALAPIEPRTAAIPFHSTVSGRPIDTAELDADY
WYRNLRETVELERVTRAAVEDGHHTFIEISPHPVLTTGLRETLDDADAHGGLVLASLRRD
DGGLTRFRTALAEAYAYGVEVDWLSVFPGARRVELPTYAFQRERYWLDAPTAEAPTSAID
AEFWAAVEREDLESLAATLRVDGQPLREVLPALSQWRRERRDVSTIDSWRYKIRWKPLTP
PATSPTGTWLVVVSHTEAEHEWVAGVTGALTRHGAEPLMVVLGEPELDRAALAARLGAAL
ADTPRISGVVSLTALDESPHPAYPSVPQGYAMTLLLSQALGDAGVEAPLWCLTQRGVSLG
DGGGNGGGAGGRGDEGNGSGNENGTGSGSGSGPGEGDGDSDVAVSRKQALTWGLGKVIAL
EQPLRWGGLIDLPNGVAPYAQDCLAGVLAGTSDEDQMAIRPTGLFGRRLAHAPAPERGGA
WQPRGTVLVTGGTGALGGHVARWLAAQGAEHVVLTSRRGMAAPGAERLAGELEALGARVT
VAACDVGDRDALAALLTEVGPLTAVVHTAAVLDDATLNSLTTEQLQRVLRVKTDGAVHLH
ELTRDMELSAFVLFSSLSGTLGAPGQGNYAPGHVFVDTLAEQRRAEGLVATSIAWGLWAG
DGMGEGGVGEVARRHGVPEMAPEMAVAAMARAVEQDETVVTVAEIDWDRHYVAFTATRPS
PLLSDLPEVRALIDAGVGQESAEPGHERSEFAERLAGMADADRNRALLDLVRRHVAVVLG
HTGPDAIDPGRAFHEIGFDSVTAVELRNRLNRATGLRLPATVTFDQPTPLAMARYLRGEL
LPDGRDRSAPARPVRTTGAVDDEPIAIVGMSCRFPGDVASPEDLWRLLADGSDAIGEFPE
NRGWDTAHLFHPDPDHRGTSSTRAAAFVSGAGEFDAGFFGISPREAVAMDPQQRLLLEVS
WEALERAGIDPSTLRGSETGVFTGTNGQDYASLLKADETGDFEGRVGTGNSASVMSGRIS
YVLGLEGPALTVDTACSSSLVALHLAVRALRSGECSLALAGGASVMTTTGIFVEFSRQRA
LAADGRCKAFAAGADGTGWGEGVGMLVVERLSDAERNGHRVLAVVRGSAVNQDGASNGLT
APNGPSQQRVIRQALASAGLSAVDVDAVEAHGTGTTLGDPIEAQALLATYGQGRDVDRPL
WLGSVKSNIGHTQAAAGVAGVIKMVMAMGHGVLPQSLHIDEPTPHVDWSTGAVRLLDEQT
EWPETARPRRAGVSAFGVSGTNAHVILEQAPEPTAEPELSPERDETRAVPWVVTGASEAG
VRAQAARLLAFVDDRPELRPVDVGWSLVSTRAALPHRAVVVGGDRDELVRELEAVAGGSA
AIGEARTHSGVVFVFPGQGSQWVGMALELVESSSVFAGRLGECAEALGPFVEWSLWDVLG
DEVALGRVDVVQPVLWAVMVSLAELWRSFGVVPSVVVGHSQGEIAAACVAGGLSLEDGAR
VVALRSRALLALSGRGGMVSVPVSADRLRDRPGLSVAAVNGPVSTVVSGSVEVLDAVLEE
FPEAKRIPVDYASHSVQVEEIREGLADALASVRPRTGEVPFYSTVTGRLMDTVELDGEYW
YRNLRETVEFRSAVEGLLELGHTVFVEASPHPVLTIGIQDTADATDITHTDILVTGSLRR
DDGGLVRFLSTVGRLFTAGVPVEWQPLFAAAGARRVDLPTYAFQHEWFWLDPVRGASDVG
GAGLAGLAHPLVSAVLPLPESDGCVLTGSLSSATHPWLRDHAVLDKVLLPGTGFVELALQ
AGLLLGCRTLDELTLQAPLVLPAHGDVQIQVAVGGPDDSGRRPVTVYSRPGQDRTWVRHA
TGSISPGGETATVDRTVWPPVDATPVDLTGVYAEMNTRGYAYGPVFQGLRAAWRRDDEVF
AEVVLPETAESDAGRCAVHPALLDAALHGAGLGTFVTEPGRPHLPFAWTGVSLHAVGATT
LRVVLSPAGPDAISLLAMDGTGAPVLTADSLALRPVSEGALGGAHNDSLFRVDWTELALA
ASDTSDEVAFPVVESLAQLTGPGAPQPVHGAVVFRPSATEASVAEATDATGAADTTEENP
EDVYALTSRVLEVAQAWLADDRFGDARLVVVTRGGVATRPGEDPESLAAAAVWGLIRTAQ
TENPGRFVLVDTVDEDPSVSSVPSVSSTSSVVSVVSALPAVLATDEPQVAIRAGKALVPR
LVRAASSALPVPAETDTWRLEADGQGTLENLVLAPHAEASRPLAAHEIRVAVRAAGVNFR
DVLLALGMYPDKAGLLGSEAAGTVLEIGSGVAGVAPGDRVMGLFSGAFGPVAITDHRLVA
PIPAGWSFPQAAATPIAFLTAMYALIDLADVRSGESVLVHAAAGGVGMAAVQVARWLGAE
VFATASPAKWDAVRACGVAPQRIASSRSTEFADRLRSDAPGGVDVVLNSLTGELLNASLG
LLRPGGRLIEMGRTDLRDAEEVMARHGVSYRAFELLDAGPDRIGRLLTELLSLFRQGVFT
PLPLRVQDVRQASDAFRHLSQARHIGKLALTIPRPLSGGTALITGGTGTLGGLVARHLVR
EHGVTELVLAGRRGDTAPGAAELLTELEAAGARVRVVACDVSDREATAALVASLPNLRSV
VHTAGVLDDAVIGSLTPERLRTVLRPKADAAWHLHELTRDRDLAEFVVFSSAAGVLGGPG
QGNYAAANAFLDALAARRRAQGLPATSLAWGFWEQRSGLTEHLTTDRLARSGVLPLSTDE
GLALFDAARATGDTLLVPMRYEPSAPGPEPVPALLRGLVRAPLARALPGPADGVGNGVTE
GLTGLAVDERLGVLLDLVRREAAAVLGHGGPESVAPRRPFKELGFDSLSAVELRNRLRTA
TGRRLEATLIFDHPTPATLARHLDAELFGATDVAAPVPAPAVAHPADEPIAIVGMSCRLP
AGVDSPEALWTLLMSGTDAISELPTDRGWSLDALYDQDPSRPGTTYAKTGGFLKNAADFD
AGFFTISPREALAADPQQRLWLEACWEAFERAGIDPLALKGTRTGVFAGAASTTYGVGQA
AAPDGSEGYLLTGNSTSVISGRVAYTLGLEGPAVTVDTACSSSLVSVHWACESLRRGEST
LALAGGVAVMTTPDLLVEFSRQRGLAPDGRCKSFAAAADGTGFAEGAGVLVLERLSDAER
NGHQVLAVIRGSAINQDGASNGLTAPNGPSQQRVIRQALANAGLASRDVDAVEAHGTGTT
LGDPIEAQALLATYGQDRDPDRPLLLGSVKSNIGHTQAAAGAAGLIKMVLALRNGVLPRT
LHVDEPSPHVDWSAGAMELLTEQTTWPDRDRPRRAGVSAFGVSGTNAHVILEQAPEPDES
GEPGTGRSGLPAVPWVLSGAGAAGLRAQAQRLASFVRENPELDPVDVGWSLVATRAALSH
RAVVVGADRAELLRELDAVQSMGAAEAGREVVFVFPGQGSQWVGMALELVESSSVFAGRL
GECAEALGPFVEWSLWDVLGDEVALGRVDVVQPVLWAVMVSLAELWRSFGVVPSVVVGHS
QGEIAAACVAGGLSLEDGARVVALRSRALLALSGRGGMVSVPVSADRLRGRAGLSVAAVN
GPVSTVVSGAVEVLDAVLAEFPEAKRIPVDYASHSSQVEEIRRELADALASVRPRTGEVP
FYSTVTGRLMDTVELDGEYWYRNLRETVEFQSTVEHLMREGHTVFVEASPHPVLTVGIQD
TADATATDILVTGSLRRDEGGVRRFLTSLAEVSVRGVEVNWWTAFDGAGARRVDLPTYAF
QRERFWLAPSTGTGDAYGLGLGAVDHPLLGAAVPLPDADGCVLTGALSLAGQPWLADHSV
LGMVLLPGTAFVELALQAGARFGCDTLEELTLHEPLVLPEQETVQLQVSVGGPDDLGSRP
FTVFSRREGDWTRHAGGTLCAGEHGDPPANPSVWPPADARPVDVAELHMTMAERGYQYGP
AFQGLRKAWIRDSEVFLDVALPEQVRVDAARCGVHPALLDAALQGIGLGAFVSEPGRAHL
PFSWSGVTLHAVGATTVRVTLSPAGPDAVAIRMTDTIGAPVLSIDALAMRPLAEQRLLEA
GGSRSDALFRLDWTELLVPTGATGSRALSWGLLGGHDEPRLTAALTAAGVLPQRHRDLAS
IDQVPDVLVLPCLPEADDGPAPEATSSALGRVLEVVREWLGDARYTDTRLVALTRRAVAT
STGDDVEDLAAAAVRGLLRTAQQENPDRLVVIDHDDSDLGVLPAVLATGEPEVAIRAGTV
LVPRLAKAAVPDGKTPAWDAGTVLITGGAGTLGGLVARHLVTTHGARDLVLASRGGDTAP
GAVELATELEALGARIRVAACDVADRAQLTALLDTIPALRAVVHTAGVVDDGVIGSMTAD
RVEAVLRPKANAAWHLHELTRRLDLDAFVLFSSATGVLGSAGQGNYAAANAFLDALAVHR
RAQGLPAVSVAWGLWEQRSGLTAHLSEQDMARMTRTGAVPLSDERGLELFDAACRSGEAT
LVATPLHLRAVAAIGTVPPVLSALAPAPPRRATETGDGGVALRQSLAEMSGAEQSQTVRE
LVRGHVAAVLRHPDGSAIDPVRTFQEIGFDSLTAVELRNRLGASTGIRLATTAIFDYPTP
ATLAEHLLAEIVPETADPVAARLGELDKVAAMISAMGEDDTLREQLSSRMETIVAMWADL
HRPERSSRVGRDLESASLDDMFGIIDQELDGS
>A0A4P7CBP6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Saccharomonospora xinjiangensis|TrEMBL
MDRNTTGENEPIAVIGLACRVPGAGTSERWWANLVSGVDSVGPPSEARRRAAVPAGPQIP
SEGGFLDSVADFDADFFGISQREALAMDPQQRLALELAWEAMEDAGIVPAALTSLPVGVY
LGSSSDDYALLLSRSGQAVSHHAMTGLQRGVIANRVSHHLGVRGPSLLIDTGQSSSLVAV
HLAVASLRSGECRMAVAGGVNLALAPESQLAAARMGVLSPTGRCRVFDRAADGFVRGEGG
GVVVLKPLSSALADGDRVYCVIRGTAVNHDGAGEDLAAPDGAAQAGLLASAHRAAGVTAA
DVQYVELHGTGTPAGDATEAAALREVFGDRDTALAVGSVKTSIGHLEGAAGVAGLIKTVL
SVHHRVLPPNLHFTAPPDGIPLAEWGLRVQTETSPWPDPASPLIAGVSSFGIGGTNCHVV
LAAHDSPEPPAEAGTTGPLPYVLSARTPAALAATARALREHRAARPDVRDVDVAFTLATG
RTAHACRAVVVARDHADLLTGLDRLASHESSGATGFLGDAVVAGTVGSFGDLAERFLAGE
EVNWEPVFAGRQVVRVALPTYPFERTTHWPAGLGAPPAESQAQPRTAPPVSEHTTATHAG
ERDAALPLDDVLDLAARVLGAAVLPDVPFSEQGFDSMMGLELRDLVEEHTGADVSVSLLY
DHPTPAALAEHLAELTGSAAAPALKPRATAVAVPPAEPGPEGGFDTDPVVIVGMGCRYPG
GVTTPEALWRLVRDRVDAITEPPAERGWHTLDTTGLRPGGFLDGIDRFDAEFFGISPREA
AAMDPQQRIFLEVVWEALENAGIVPGTLRGSRTAVFAGATAQDYGARLHEQADSAGGFLL
TGGTPSVLSGRVAYVLGLSGPALTVDTACSSSLSAVHLACRSLRTGESSLAIAGGVTVMA
LPGMFTEFDRQNGLSPDGRCRAFSADAAGTGWAEGAGVLVLERASDARRNGHRILAVVRG
SALNSDGASNGLTAPSGLAQRQVIADALADAGLRPADIDAVEAHGTGTTLGDPIEATALL
AAYGEGRQPDRPLRLGSVKSNIGHTQAAAGVAGVIKMVAALHHGELPATLHAEQPSPHVA
WSAGTVALLTEPVPWPRTTRPRRAGVSSFGISGTNAHVIIEEAPHVVDEPVRDIGDRPVV
LAVSARTEPALRAQAARLRDHLSGDHGSGDWSPADVAHSLLTTRTRFPVRAAVTGTTRQE
LLRGVSAIADGGADPAVVSGNATAAHRPVFVFGGQGGQWAGMARDLLDASPGFAEAIADC
ERALSPHVEWSLTGVLREAPGEPGLDRVDVVQPVLFATMIALARLWRAHGVEPSAVIGHS
QGEIAAACVAGALSLDDAALVVARRSRALTALAGRGAMASIGLPADRVRGLLSGMDGAGG
AVSIAACNGPNATTVSGDPAEVAALVERCTADGIRAKAVAVDYASHSAQVTELRERLLAD
LAPIRPGVPSIPMMSTVDVEKVDDAVLDAHYWYRNLRQEVRFDDAVTALVGEGHRTFVEV
SPHPVLLSGIAERADELGEPVVTLESLTRGEGGLERFLRSLAKADAHGVPIDFSAAFPGR
VVPLPTYAFQRDSHWLTVPAGTGDLTAAGLTAASHPFLGAEVEHADGGDVLLTGSLSLGG
AAWLADHAVLDTVVLPGTACLDLVAWVGRRLGCPEVRELVLDSPVVVPDEAALRVQVVAS
APDGDGSRTITLHTRQDGDATGWVCHATASVEPGERPVGAALESHWPPPDATEVPLTGHY
ERLRAIGLDYGPVFRGLRGAWAEGDRLWLDVALPEGGEGDFGLHPALLDAALHGIWLRPG
DDGTCRLPFSFGGVRLSTTSATRLRVRLDTVDDSTVSLLAWAEDGTPAVAVDHLALRPVS
PEKLTAAPALFSLSWADVAAEGDSGAEPVDADPVVLTDGLPARPPEVAVLECPAGDDPAR
AARQVLDVVRSVAGDERTVASRLVVATTGGDGELSDPAHAAVWGLVRSAQTEHPGRFVLL
DTDRADSAVVTGALATGEAQVRFRGGRFATPVLRRASRPTRHALPRLGGTALITGGTGEL
GGLIARALVTTYGVRRVVLLSRRGPDAPGAAELVGDLTALGAEAQAVAGDAADSAVLDRV
LAGLPSDRPLTTVVHAAGVLADAPVSMMDDAALDTVLRPKAAAALALHEATRNLPTVAAF
VLFSSVAGILGTAGQANYAAANGVLDALARRRRAEGLPATSIAWGLWSQRSGLTGALDDT
AVRRLAALGIGQLGTDDGLRLFDAALREPSPVVVAAALLGKGRSGLLRGLAPARPHRSAQ
REPSRTVIDELPALPARQRAARVLELVLDHTAAALGHSSSGALDTSASFKDLGCDSLIAV
EIRNRLATATGLTLPATVVFSHPTPAELAGWLLDRLVPGPRPAEDDRDAGHAETGAVGKS
TVVGQSAAPATAAVNRLAATSAAVPAVPAVPAAAPAVDVAPATPAVSGVSGDGTDDPDLD
RELAEADVTELFALIDADPDDEWAAVSGGEGADGR
>A0A2K8QW67|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MAAKSALTKAAEYSRGVAGHLVDPDTTMAVIGVSCRFPGAENPDRMWRLLTAGESSVGEV
PPGRWSGPAAEETPRFGAYLERPEEFDAAFFGISPREAPYVDPQQRLALELGWEALENAR
IVPDQVRGTRLGTFVGVSGDDYAQLLSPHVHTLATQHALPGVQRGVIANRLAAFLGARGP
SITVDSAQSSSLVALHLACGSLRGEESDMALVCGVNLHLLPQSVLLASRLGALSPRGRCF
TFDERADGYVPGEGGGAVVLKRLRTALADGDRILCLVRGSATTNDPDGVTLTAPTVAAQA
EALALAYRHAGIAPDAVDYVELHGTGTPTGDPVEAAALSEVIGRHRPADRPLVVGSVKTN
IGHLSGAAGIAGFIKTVLALAHRQLPPSLNFDRPHPRIPLDTLNLRVQRQLGPWPGAPAA
DRSLVAGVSSFGMGGSNCHVVLSDWHPEPEPARPEPDPLTVPWLLSGRGEAALRDAASRL
GNSDAARDPEVSAADVAWSLASSRSAFERRAAIVAPTRDDLLAGVRALAEGSTAPGVLTG
TAVPGGVGVVFSGQGSEHGGMGAGLARFPVFAEALAEVCQVFDEVAGEVADEVGLSEEAR
ERFGVERGEFGALLRRVMAEGAGDGEAGLGGTGWAQAGLFAFGVAAWRLVSSLGVVPSVV
AGHSVGEVIAAHVAGVWSLRDAARVVLARGWLMEPMLEEFGRVLGSVEFAAPRLAVTSNV
TGRVAEPELLRNPAYWARHVEETVRFADEVSAMRAQGVSTFLEIGPGAALTPMIKESVRA
SAPGAEQPPDVSAVPLCRRDLDEGQSLVQALAQLWARGTDVDWEPLLGAARQVDLPTYPF
QRQRFWLDVDTPVAASAPASAPTPTPDPIPASATAPAGKPSGTSPRTPRALPDLLRLVRE
QTGAIMRDSGPVDTALTFRDLGFNSLMTEELAEALAARTGLPLKAEAVFGYPTPAALAEH
LRDALTSIEHTPDTREQPAADEPLAIVGMACRYPGGVASADDLWRLLASGGDAIGGLPTD
RGWAPDILHGADSGDHVPAGGFLYDAGDFDADFFGISPREALAMDPQQRLLLESSWEALE
RAGMDPAGLRGSATGVYIGATTQDYGPRAYGAPEYLTGHVLTGSTPSVLSGRVAYSFGFE
GPAVTVDTACSSSLVALHLAGRALRSGECDLALAGGVTVMATPGMFIEFRQQQGLAVDGR
CKPFSAAADGTGWGEGVGVLVLERLSDARRHGHQVLAVVRGSAINQDGASNGLTAPSGPS
QQRVIRAALADAGLSADEVDAVEAHGTGTRLGDPIEAQALAEAYGRGRDPERPLWLGSLK
SNIGHTQAAAGVGGVIKMVQAMRHGTLPASLHAEEPTPRVAWESSGLELLVRPREWPERA
GRLRRAGVSSFGISGTNAHVIVEEAPAVAESGSGRDVPSGVVPWVLSGRSGAALRGQAER
LAAFVESRPEVSLADVGASLANGRAVHDHRAVVAGTGRDELLDAVRALARGTTEGAAVVG
ERDDAASRVVFVFPGQGAQWVGMAAELLADSPVFAARMRECAAALKPHLEVPLLEALGDS
AALDRVELVQPALWAVMVSLAEVWRSYGVVPSAVVGHSQGEIAAAVVAGALSLEDGARVV
ALRSRAVAAELSGRGGMAVVRVPADEARRVIGDLRDVVSVAAVNGPATTVVSGTPEGLEA
LEVRCGREGVRFRRVAVDYASHSAQVDALRDRILADLAPIRARRAEVPFFSTVVGAWLGE
GVPDASYWADNLRRPVRFEEGVRALAAEGFGAFVECSPHPVLTGDIQHTLEEAGQDAAVV
GSLVRDDGGPRRLLTSLAEAFVRGVPVDWAQVFAGSGTRRVDLPTYAFQHERYWFDADTG
TLDVSAAGLTPARHPLLGAAVRTADGGTLVLTGRIAAHTHRWLYDHTVGTLALLPGTALL
ELAVQAGDRYGAPHVGELVLHAPMVLPGPGGAADLQITVTASGEPGRATATVQARPATDG
ADAPWTHHATATLTATPPIPARPVSDWATTWPPAGATPTGPDDVYADLADTGYTYGPAFQ
GLSHLWAAPDGTVYADAHLPERDQDGTSTGTATGTVTGDGDGYALHPALLDAVLHAVSAG
RVLGGELRLPYAWGDVALHAAGARALRARIARTGEGEVAIDLADAAGRPVGSIGSLTMRP
ADTARLGAPTGAAARSLFGVEWDALSPGDPRPTGHWALLAGDDGPVPAALRDSGTLPATA
AAYRDVGRLRTALDAGDAVPDVLVWLVPHVDGDPVTAAHAHAAAALETARALLLDDRMTA
TRLLAVTEGAAGPDAVTDVAAATVWGLLRTAQTETPGRFLLVDTDRHRESLRLLPAVAAG
VEPQVALRAGRAHTPRLARATAVAANATTPFGPDGTVLLTGASGRIGGLLARRLVHEHGV
RRLLFVSRRGADATRDLAAELTDAGCEVTTVACDPADRGALAAALASVRTEHPLTAVVHA
AGATDDGAVTSLTAEQLAKVLRPKVDAAWHLHELTREEPLTAFVVLSSVSGVLGTAGQAN
YAAANAFLDALAAHRSHLGLPGQSHAWGLWDQDGGGGGMASGLDDTDRSRLARLGVVPLP
EDEALALFDRAVIDPRPLMVPAKLDVRPVRERAPQDGVPALLRRVVRPPRTTGGNADSPF
AARLAALAPDERPGLALDLVRAKAAAVLGHAVAERVPATRAFKDIGFDSLGSLELRNRLN
TETGLRLPVGLLFDYPTPTALATFLVGELAGAAEATPGEERPADTALSAVTAHTARTDEP
LAIVGMACRYPGGATSPEALWELVSTGADGIGPFPADRGWDLDGLYHPDPDHPGTSYTRE
GCFLYGAGDFDAGFFGISPREALVMDPQQRLLLESSWEALERAGMDPAGLRGSATGVYIG
ATTQDYGPRAYGAPEYLSGHVLTGSTPSVLSGRVAYSFGFEGPAVTVDTACSSSLVALHL
AGRALRSGECDLALAGGVTVMATPGMFIEFGQQRGLAVDGRCKPFSAAADGTGWGEGVGV
LVLERLSDARRLGHRVLAVVRGSAVNQDGASNGLTAPSGPSQQRVIRAALADAGLSADEV
DAVEAHGTGTTLGDPIEADALLATYGRGRDPERPLWLGSLKSNIGHTQAAAGVGGVIKAV
QMMRHGVLPASLHAGEPSPHVDWSPGTVRLLAEPLDWPDTGRLRRAGVSSFGISGTNAHV
IVEEAPAVAESGSERGELPVVPWVLSGRSGAALRGQAERLAAFVESRPEVSLADVGASLV
NGRAVHEHRAVVAGTGRDELLDAVRALARGTGVGGEVRGDDAEPRAVFVFPGQGAQWVGM
AAELLADSPVFAARMRECAAALKPHLDLPLLEVLGDAVALERVDVVQPALWAVMVSLAEV
WRSYGVVPSAVVGHSQGEIAAAVVAGALSLEDGARVVALRSRAVAAELAGQGGMAAVATS
EDEVRRLVEDIEDVVSVAAVNGPATTVVSGTPEGLEALEARCGREGVRFRRVAVDYASHS
AQVDALQDRILADLAPIRARRAEVPFFSTVVGAWLGDGVPDASYWVHNLRRPVRFEEAVR
ALAAEGFGAFVECSPHPVLTAAVQETLDAAGHEAIVAGTLRRDDGGARRLFTSFGEVFVH
GVPVDWSQVFAGSGARHVDLPTYAFQHERYWWDPAALRKPAIPRDTAGPADDTGFWGAVE
SGDTETLAGTLDIDGASLAPVLPALRNWHRHRSAAAAVASWRYHTRWVPASLPDTPALTG
TWLLAVPAGSAVAADRAAEVAAAVRDHGGEVTTLELPATATREDIARRLPGGTYAGVLSL
LSAADGPVTADGIPRTGLTATVALFQALGDAGTGAPLWCLTHDAVTATDQDLRTHRDSAA
AQHMVWGLGRIVALEHPERFGGLVDLPARPDARTGRLLAALLSGTTGEDQVALRPSGALV
RRLARAAATGSHPAWRPRGTVLVTGGTGGLGARVARHLAGSGAEHLVLASRSGPDAPGAA
ELSAELEAAGVRVTVAACDVGDRADLARLLDAVPGDCPLTAVVHTAAVLDDAVVERLTPG
QIDRVLRAKADGAWHLHELTRDSDLDAFVLFSSVAGTLGASGQGNYAPGNAYLDALAEQR
HALGLPATSVAWSIWDERGMATEDGIGTLARRHGLLVMAPDLAATALTVVAGEPEPTVMV
ADVEWDRFHVAYTATRPSPFLADLPEVRRLTTVTPADESAPRAATGSGDLVARLTALGGH
AEQQAVLLTAVREQVAVVLGHTGPDAVDPGTAYRDLGFDSVTAVELRNRLNSVTGLRLPP
TIVFDHPNARALAAHLHSEILGGAPAPDTLPTPPAAPTMAAEEAEDPIVIVGMSCRFPGD
VRSPGDLWQLLKTGGDAITPFPEDRGWDLDALHAPGSDRTGTSYTREGGFLSDAADFDAG
FFGISPREAMAMDPQQRLLLETSWEALEGAGIDPTALRGTRAAVFTGTNGGDYLAMGHDV
PEEAVGYAATGNIGSVLSGRVSYALGIEGPAVTVDTACSSSLVALHLAARSLQQGECDLA
LTGGVTVMSTPGIFTEFTSQGGLAADGRSKAFAANADGAGFAEGVGVLVVERLSDARRNG
HRVWAVVRGSAVNQDGASNGLTAPNGVAQQRVVRAALADAGLSAGDVDVVEAHGTGTKLG
DPIEARALLATYGQGRDPRRPLWLGSVKSNIGHTQAAAGVAGVIKTVLALHHAQLPRTLH
ADQPSPHVDWSSGAIRLLVEPRDWPDTGRPRRAGISSFGVSGTNAHVILEQGPDPRATPE
SRAVPEGTVVPWTLSAKSVAALREQASRLLPLLAGDMSTTDIGHALATTRARFDHRAVVL
GASTAERRDALDSLATGKDTPAIVRGTTVTSDDRVAFVFPGQGSQWVGMALELLESSPVF
ARRMGECADVLGRLVEWSLWDVLGDEVALGRVDVVQPVLWAVMVSLAEVWCSFGVVPSAV
VGHSQGEIAAAVVAGGLSLEEGARLVVLRSRVLVGLSGRGGMVSVGAGVGVVRGLVESFG
GGLCVAAVNGPSAVVVSGDVGVLEGFLAECEGVGVRAWRIPVDYASHGVQVEEVRGEVEE
AVSGVVSGVGVVPFYSTVTGGVLDMAGLDAGYWYRNLRFPVRFEETVRVLLDAGFRQFVE
VSAHPVLTLGVEQTAEDHGVEVSVVGTLRRDEGGRGRVLRSLAEAYVAGAPVEWARVYGD
TGARRVDLPTYPFQRQRFWIRQHGGAGSATTAHGMAATGHALLGSGVPLPGSDGFLFTGR
LSLRDQPWLADHSVLDRVVVPGTAFLDMALHAADTVGCDHVTELTLETPLVLTTTGTTHV
QVLVTAPDHEGNREISVHARAQDAPPHAWTRHARATLAAGVSGEPAGLGSWPPAGARPVE
TAGLYERLSDQGLAYGPVFRGLETLWRDGDGALFAEVTLPDVADSDTAGFGVHPALLDAA
LHAWAAGSDDAGAGDAGPGAVRLPFLWSGVTLHATGATKLRVRLTPVASAEGALSVLVTD
AAGLPVLSARSLVTRPVTEATFPAPSGTGGSLYRVAWSPVTGSGPETGPEAGAAPRVAVL
GEGTESLPEPDPALADCRDLAALEGRLAAGEQPVPDQVLAEVSAPGGDWLPAVAEHTARH
ALELVQRWLASAHFSASRLVLVTQGAVAAAEGDEPMAGLTASPVWGLVRSAQTEHPGRLA
LLDLDPRGTTPDVVRRALASGEPQLAIRGEEILAPQLVRDEPDEPDAPDESTDARHTGPW
HLTSARNGTLEDLAWTPVPSDPVSDAVPRLLGAQEVRIEVRAVGLNFRDVLVLLGMYPDA
ESAVLGSEGAGVVVEVGSGVTDVCVGDRVMGVWGDGFRSVVVVDVRGVVGVPVGWSFEQA
ASVPVAFVTAYYALVDLAGVRAGESVLVHSAAGGVGMAAVQLARYLGAEVFATASESKWS
VVRGLGVSGERIASSRSVEFERVFGSGVDVVLDSLAGELVDASLRLVRPGGRFVEMGKSD
VRDAGEVAEAFGGVWYRAFDLAEAGVERMGEVLREVVGLFEAGVLELLPVGVGDVRRAGE
VFGVMRRARHVGKLVLSVPSAVDGGGWVVVSGASGVLGGVVARHVVVERGVRRLLLLSRR
GEDAPGVEGLVAELVAAGAEVRVVACDVADRDALAGVLSSLEGGVSGVVHAAGVLDDVMV
ESLSAERLAGVLAAKVTGAWNLHELTLNRGVRWFVVFSSAAGVLGAAGQANYAAGNAFLD
ALAAFRRSRGLPGVSVAWGLWEQRSVMTEGLDDIDLTRFARMGVVPMRNDDGLRLFDAAA
ESARSLVVAAELDSRALGAADRDTPVQPMLRGLAERQVAPRRRWTASAGDGTQPDGAPLA
RQLVGLGKGERRRVLLHTVREHAATVLGHGSAESIPAEQGFLDMGFDSLTAVELRNRLSA
ATGLRLPATLVFNHPDATRLADHLGAELMPPDTVDDADTALRAELDRLETRLRDSAADTD
GATRAMVVTRLQDLLSHWSTAPNGSAAANGSTPPNGNAAPNGSTARNGSAASDDAGAGGA
ADVAENLESAGADELFSFIDREFGSH
>A0A2K8QUJ9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MPDHDKLVEYLRWATAELHTTRAKLQAATEAGTQPLAIVGMACRLPGGVSSPEDLWRLVE
SGTDAISGFPVDRGWDVDGLYDPDPDVPGKSYTVEGGFLDAVTGFDAPFFGISPREALAM
DPQQRLVLETSWEAFERAGIEPGSVRGSDTGVFMGAFPGGYGTGADLGGFGMTGGAASVL
SGRVSYFFGLEGPAMTVDTVCSSSLVALHQAGYALRHGECSLALVGGVTVMSTPQTFVEF
SRQRGLAADGRCKAFADNADGTGWSEGVGVLLVERLSDAQARGHNILAVVCGSAVNQDGA
SNGLTAPNGPSQQRVIRQALANAGLTTAEVDVVEAHGTGTTLGDPIEAQAVIATYGQDRD
QPVLLGSLKSNLGHTQAAAGVSGVIKMVMALQNGVVPRTLHVEEPSRHVDWTAGAVQLVT
ENQPWPELGRARRAAVSSFGLSGTNAHVILESAPDQPPAPTTDTPAPAATAGVVPLSISA
KSLPALADLEDRLRAYLTTTPEADLPAVASTLATTRSLFEHRAVLLGEDTVTGTAIPDPR
IVFVFPGQGWQWQGMGSALLTSSAVFAERMAECAAALSEFVDWDLLTVLDDPSIVDRVDV
VQPACWAVMISLAAVWQAAGIHPDIVLGHSQGEIAAACLAGAISLPDAARIVAQRSQLIA
HQLTGHGAMASISLPADDIPTTDQVWIAAHNGTSTVIAGDPQALDTLLATCETRGARVRK
INVDYASHTPHVEQIRTELLDITTGIEAQTPAVPWLSTTDNTWIDQPLDPTYWYRNLRQP
VRFGPAIDLLQTQDNNLFIEISASPVLLQTMDNAATVATLRRDEDTTHRLLTAFAEAHVH
GATIDWPTVLDTTTTSALDLPTYPFQRQRYWAIGNGRPTGQGHPLLETVVALPGTDEVAL
TGRISLATHTWLTDHTVRGTVLLPGTAFVELVTRAATEVNCQIIDELVIEKPLTLPQTDG
VQLSVTVGEADEAGHRPVTVYSQTDESDDWVQHVTATIGPGASLPETSAWPPAHAEPVNV
TGLYDNLAAAGYEYGPAFQGLQAAWRAGDTVYAEVTLAEEQAQETARFTMHPALLDAALH
TIALHDTGDLHLPFSWTRVQFHGSGAATLRVAVTPAADGWNIRATDDTGQTVATIGSLVT
RPMAAETTDDLLALSWMEIAALKPVDPTDVVVFTALPDTVEDVPAQTRALTTRVLHTIQE
WLADDDRTLIVRTGTDLASAAVSGLVRSAQSEHPGRFILVESADETLTQEQLAATAGLDE
PRLRITGGRYEVPRLTREDTALAVPTDRAWLLEQPRSGSLEDLALLPTDAAERPLQAGEV
RIGVRAAGMNFRDVVVALGMVTDTRLAGGEAAGVVLEVGTDVDDFRPGDRVFGILEGGFG
SVAISDHRTLAVIPDGWSFTTAASVPIAFATAYYGLLDLAGLRAGESVLIHAATGGVGIA
ATQIARHLGAEIYGTASVGKQHVLRDAGLGDDRIADSRTTDFRDTFRDGTEGRGVDVVLN
SLRGEFIDASLDLLVDGGRFIEMGKTDIRDAAQIPDATYHAFDLMDAGHDRLREIMTELL
ALFEQGVLHPMPVHAFDIRQAREAFSWMSRARHIGKLVLTIPQPIDPDGTVLITGGSGVL
AGIVARYLVTENRARRLLLLSRSAPSASLIDELTALGAHVDVAACDVADRAALAEILDGV
DLTAVIHTAGALDDGVVESLTPQRLDTVLAPKADGAWHLHELTRDRDLAAFIVYSSAAGV
LGAAGQGNYAAANAFLDALAVHRRLEGLPGLSLAWGLWEDASGLTADLTDADHDRIRRSG
QRAITAAYGMRMLDAATRQSEAVLLAAPISPIQDGDVPAILRSLHRRVGRRASVAHGHPA
DLTPEALLKVVRDSAAMVLGHTNADTVPTATAFQELGLDSLTAVELRNSLTKATGLRLPA
TMAFDYPTPDALAARLGELLAGEAAPKAAAAVRRATASDEPLAIVGMACRLPGGVSTPED
LWRLVESGTDAITDFPADRGWDTDSLFDPDPDTAGKTYTVHGGFLDDVAGFDAPFFGISP
REALAMDPQQRLVLESSWEAFERAGIQPDSIRGSDTGVFMGAYPDGYGIGADLAGFGVTA
GAGSVLSGRVSYFFGLEGPAMTVDTACSSSLVALHQAAYALRQGECSLALVGGVTVMPSP
RTFIEFSRQRGLAADGRSKAFADAADGTGFSEGVGVLLVERLSDAQAKGHNILALVRSSA
VNQDGASNGLTAPNGPSQQRVIQSALAGAGLTSADVDVVEAHGTGTTLGDPIEAQAVLAT
YGQDRDQPVLLGSLKSNLGHTQAAAGVSGVIKMVMALQHNTVPATLHVDQPSRHVDWTAG
AVRLATENQPWPETNRPRRAGVSSFGVSGTNAHVILEQAPAAGPVEPVDTTDVVVPLVVS
ARSSGSLSDQADRLAALVSSPDAPALTSLADALLTRRTVFSQRAVVVADSQEQAAAGLRA
LAAGDSHPALVTGAADPARGVVLVFPGQGSQWAGMGAELLDASPVFAARIAECAEALRPW
VDWSLDEVLRGDAPADVLGRVDVVQPASFAVMVGLAAVWESAGVRPDAVLGHSQGEIAAA
YVAGALSLTDAAKIVAVRSRLIAARLAGRGGMASVALAPDEAAAKLGRTELAAVNGPASV
VIAGDAEALDETLAMLEGEGVRVRRVAVDYASHTPHVEELEQSMAEALADVRSRQPRVGF
LSTVTGDWVTEAGALDGGYWYRNLRQPVRFGPAVASLAEAGYAVFVEASAHPVLVQPVAE
TLDRTDAVVTGTLRRQDGGLPRLLTSMAELFVGGVPVNWPVLLPAGAVRGWVDLPTYAFD
HQRYWLENRVATDAAALGLAGADHPLLGAIVAVPQSGGVAMTSRLSPRSHPWLAEHTLGG
VPTVPTSVLVELAVRAGDEVGCGVVEELTVDAPLLLPERGGVRVQVIVGATDANGQRGLD
IFSAPEDTGQEAWTRHATGTLAPGGDIAADVDLSAWPPANAQPVDVTDGYELLERAGYGY
GPAFQGVRAIWRRGEELFAEVALEPELTDTAARFGLHPALLDAAWHPELRDEVAETSPDG
RRWWSQPSRWAGLRLHTAGATVLRVRLAPVDADSMSLQAADETGDPVLTVDSLSLCAVSA
DQLTTAESSDDALFRLEWTPLSKAPTAATSWVPVETGADVAALDGQAVVDAVMLEAAGTG
DALELTCRVLEVVQAWLTLPGWDESRLVVVTRGAVGAVGDPAGSAVCGLVRAAQAENPDR
IALLDLDGGRPVEPLLADGEPQLAIRGAEALVPRLIRAAAATDAPALFDESQTVLITGGT
GSLGGLLARHLVGRYGLRRLVLVSRRGPDAPGAYELAAELAAHGAEAALVACDLTDRDAV
ARLLTEHHPTAVVHAAGVSDDGVIGTLTSDRLAYVFGPKATAARHLDELTRELLPDLAAF
VTYSSISAVFLGAGSGGYAAANAYLDGLMARRHAEGLPGLSLAWGLWDQEADGGGMAAGL
QDITRNRMRRRGGVLSFTPAEGMALFDAAMATGEALVVPVRLDLPALRAEAVAEGRSAPV
LLRGLVRPGRRLARTVSGGTGVLADLTPEALLKLVRGRAAAVLGHVDADAVPVAAAFRDL
GVDSLTAVELRNSLAKATGLRLPATLVFDYPTPTVLAGRLGELLAGGTAPVRAAVVRRAA
ASDEPLAIVGMACRLPGGVLSPEDLWRLVESGTDAIADFPADRGWDTDTLYDPDPDAAGK
TYTVRGGFLDGAAGFDASFFGISPREAQAMDPQQRLVLEVSWEAFERAGIEPGSVRGSDT
GVFMGAYPGGYGMGTDLGGFGMTSVAVSVLAGRVSYFFGLEGPAMTVDTACSSSLVALHQ
AGSALRQGECSLALVGGVTVMPTPQTFVEFSRQRGLAADGRCKAFADAADGTGFSEGVGV
LLVERLSDAQARGHNILAVVRGSAVNQDGASNGLTAPNGPSQQRVIQSALAGAGLTSADV
DVVEAHGTGTTLGDPIEAQAVIATYGQDRDQPVLLGSLKSNLGHTQAAAGVSGVIKMVMA
LQNGVVPRTLHIDEPSRHIDWTAGAVELVTENQSWPEAGRARRAAVSSFGISGTNAHVIL
ESAPAQPVPPVDTPVSDVTAGVVPLPISAKSLPALADLEDRLRAYLTTTPETDLPAVAST
LAMTRSVFEHRAVLLGEDTVTGTAIPDPRIVFVFSGQGSQRVGMGEELAAAFPLFARLHR
QVWDLLDVPDLDVDDTGYVQPALFALQVALFGLLESWGVRPRAVIGHSVGEVAAGYVAGV
WSLEDACTLVSARARLMQALPAGGAMVAVPVSEERARAVLVDGVEIAAVNGPASVVLSGD
ESAVLRVAEGLGRWTRLSASHAFHSVRMEPMLEEFRQVASQLTYQEPRIVMAAGEQVTTP
EYWVRQVRDTVRFGDQVAAFEDAVFLEIGPDRTLSRLIDGIAMLDGDDEVRAAVAALAVM
HVQGIGVDWPAILGTTTGRVLDLPTYAFQHERYWMVSTGRVGGEGHPLLGWGVPVAEADG
RLYTGRVARQDGPVLPVAAFVEMAFAAAGGQPIRELSVDALLYIPDDGTAELQTWVSEHR
LTIHARYRDTEPWTRLATATLDTTTPATTHTPHPGLITTALTLTGDEAPAIWHDLTLHTS
NATELHTHITPGDDGTLTITATDTTGQPVLTAHTATPTTIPVHTPTTPADDLLTLTWTQI
PTPGPGDPTDIAVCTALPDPDSDPLTQTRTLTTQVLHSIQTTLTAENRPLVVHTGTGLAS
AAVSGLVRSAQSEHPDRFILVESDDETLTPDQLAAAAGLDEPWLRITSGHYEVPRLTKTT
TTATTTVSEPVWNPDGTVLITGGSGALAGILARHLVTERGVRHLLLISRSTPSTTLIDEL
RELGAHVDVAACDVSDRAALARVLDGVDLTAVFHTAGALDDGVVESLTPQRVDAVLRPKA
DGAWYLHELTRDRDLAAFVMYSSAAGVMGAAGQGNYAAANAFLDALAEHRRADGLPALSL
AWGMWDDTDGMTASLSGTDHRRIRRSGQRAITAEHGMRLLDKASGRSEPVLVATAMNPIP
DTDLPALLRSLYPKTARKSQPIQELSPEALLKIVRDSAAMVLGHANADTVPTATAFQELG
LDSLTAVELRNSLTKATGLRLPATMAFDYPTPDALAGRLGELLAGDTTPATAAVVRRATA
SDEPLAIVGMACRLPGGVSSPEDLWRLVESGTDAITDFPTDRGWDTHTLFDPDPDTPGKT
YTVHGGFLDDVAGFDASFFGISPREALAMDSQQRLVLEAAWEAFERAGIEPGSVRGSDTG
VFMGAYPDGYGIGADLGGFGATAGAGSVLSGRLSYFFGLEGPAITVDTACSSSLVALHQA
GSALRQGECSLALVGGVTVIANPQIFVEFSRQRGLAADGRCKAFADNADGTGFSEGVGVL
LVERLSDAQARGHNILALVRSSAVNQDGASNGLTAPNGPSQQRVIRQALANAGLTGAEVD
VVEAHGTGTTLGDPIEAQAVLATYGQDRDRPILLGSLKSNLGHTQAAAGVSGVIKMVMAL
RHDTVPATLHIDEPSRHIDWTAGAVELVTENQPWPVLGRPRRAAVSAFGVSGTNAHVILE
SAPDQPALPTDSPATDTPAPAVTAGLVPLPISAKTLPALADLEDRLRTYLTTTPDTSLPA
VASTLATTRSLFEHRAVLLGDDTVTGTTIPDPRVVFVFPGQGWQWQGMGSALLTSSTVFA
ERMAECAAALSEFVDWDLLTVLDDPSVVDRVDVVQPACWAVMISLAAVWQAAGIRPDIVL
GHSQGEIAAACLAGAISLPDAARIVAQRSQLIAHQLTGHGAMASVSLPADDIPITDEVWI
AAHNGTSTVIAGDPQAVEAVLATCETRGARVRKINVDYASHTPHVEQIRTELLDITTGIE
AHTPAVPWLSTTDNTWIDQPLDPTYWYRNLREPVRFGPAIDLLQTQDNNLFIEISASPVL
LQTMDNAATVATLRRDEDTTQRLLTAFAEAHVHGATINWPTLLNTTTTPVLDLPTYPFQR
QRYWATSNGRPTGQGHPLLETVVALPGTDGVALTGRISLATHTWLTDHTVRGTALLPGTA
FVELVTRAATEVNCQTIDELIIEAPLPLPQNGGVQLSVTVGQADEAGCRPVTVYSQTDES
DDWVQHVTATIAPGVSLSESAAWPPAQAEPVNVTEFYDELAAAGYEYGPAFQGLQTAWRD
GSTVYAEVTLAEEQAQETARFTMHPALLDAALHTIALHDTADLQLPFSWRQVQFHGSGAA
TLRVAVTPAADGWNIRATDDTGQAIVTIGSLVTRPMAAETTDDLLALTWTEIPAPEPVDP
ADVVVFTALPEPGSDPLTQTRTLTTRVLHTIQESLADDDRTLIVRTGTDLASAAVSGLVR
SAQSEHPGRFILVESDDETLTHEQLAATAGLDEPRLRITDGHYEVPRLTREDTALAVPED
GAWMLDQPSRSGTLQDLRLVPTDAAERPLRPGEVRVGVRAAGLNFRDVAVALGMVTDTRL
IGGEGAGVVLEAGPDVEDLRPGDRVFGLLEGGFGPVAVADRRALALIPDGWSFTTAASVP
IAFATAYYGLLDLAGLRAGESVLIHAATGGVGMAATQIARYLGADVYATASTGKQHVLRD
AGLSDDRIADSRTTDFRETFRDSTDGRGVDVVLNSLKGDFVDASLDLLVDGGRFIEMGKT
DIRDAAQIPDATYRAFDLMDAGPERLREIITELLALFEQGVLRPLPVHAFDIRQARDAFG
WMSRARHIGKLVLTIPQPIDPDGTVLITGGSGVLAGIVARHLVTAEGLRNLLLLSRSAPS
EALIGELTALGAQVETVACDVADRAALARVLDGVPLTAVIHTAGALDDGVVESLTPQRLD
TVLTPKADGAWHLHELTRDRDLAAFIMYSSAAGVLGAAGQGNYAAANAFVDALAVHRRFM
GLPALSLAWGLWDDTSALTAGLTDSDHDRIRRSGARTITAEHGMRMFDAAARQSEAVLLA
APMGPIRGEDVPALLRGLATVRQPRTRAKRDVGPERLRDRLNGRTSVEQHRIMVELVLAH
ATSVLGHESPDAIAPDRAFKDLGMDSLTAIELRNHLVAETGVRLPATTAFDHPTADDLAK
RLLAEVGLAQAPRRTEAGIREEVVVREPVGDDSWTSEPIAIVSMSCRAPGGVDSPESLWR
LVESGTDAITDFPGDRGWDVAGLYSPDPDTGYKTYCVQGGFLDAAADFDAAFFGISPREA
LGMDPQQRLLLETSWEAIERARIDPRSLRGRNVGVYVGGAAQGYGVGAIDQQRDNVITGS
SISLLSGRLSYALGLEGPGVTVDTACSSSLVALHLACQALRQRECSMALVSGVSVIPTPD
VFVEFSRQRGLAADGRCKSFSASADGTIWAEGVGVLVLERLSEATRLGHRVLAVVRGSAV
NSDGASNGLTAPNGVSQQRVIRQALTGAGLTAADVDVVEAHGTGTKLGDPIEAEAILATY
GQDRSTPVCLGSLKSNIGHAMAASGVLAVIKMVEAMRHGLIPRTLHVEEPSPHVDWASGD
VALLTENQPWPDDAKLRRAGVSSFGLSGTNAHVVLEQYRAPAAPDITTTERQPLAWTLSA
RDPKALREQAGRLHAALTESPRWRPLDIGYSLATTRSNFAHRAVAVGSDREDLLRALSKL
ADGSAWPALVTATAKDRRVAYLFDGQGSQRPDMGSGLYERFPAFARAWDRISAEFGKHLD
HSLTDVYLGRGDAATADLVDDTLYAQAGLFTMEIALFELLAEWGVRPDFVSGHSIGETAA
AYAAGVLSLEDVTTLIVARGRALRQVPPGAMVALRAGEDEAREFLGRTGAALDLAAVNSP
TSVVVSGASEAVAGFRARWTESGREARTLNVRHAFHSRHVEAVLGEFREVLESLTFSTPA
LPVVSTVTGRLIEPTELSTSEYWLRQVRQTVRFHDAVRELSGQGVGTFVEIGPSGALASA
GLECLGDEASFHAVQRPGSPGDVCLMTAVAELHAGGTTVDWATVLAGGRATDLPVYPFQH
GSYWLAPVTRATDGAPSAGVPAPGEYARPSAPEEPRTMLELVRLEAAIALSITDPGLIAD
DSSFLDLGFDSISALRLSNRLAAVTGLDLPPSLLFDHPTPAELAARLDELSAADLDGAGV
YALLEEIDELDDEDLDMTEEEHTAISELLTKLSAKWSR
>A0A445NI04|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces netropsis|TrEMBL
MTARLFAVAAGTEDLLRALLAGHLDRIRTRGDLPPLARYCHDAATDTAGPYRVAFAVESY
TELEKQLAQVCAGEVERLPAELATRRPPLVFVFAGQGAQWDGMGRELLATEPVFREAMHR
CDRLVREFAGFSVVEQLGLPPEAARLDELDVLQPTMVSLQIALTALWRSWGVSPDAVVGH
SMGEIAAAHTAGALTLRDAVMIACRRSALLRRIAGKGALATTELSPAEAQAVAEASGGKI
TVAGENSPRSTVLAGDARSLAELVDELGRRDVYCRVIKATVASHSPYVEELREDLHTALR
SLEPTATRVPMYSTVTSEPVPGTDLGAAYWMRNLREPVRLAAAVENLFAAGHEVFVEVSA
HPVLLSPVRQTLESGERQGWLLPSGRRREERRSVLSSLGTLYACGREPNWSALSPGGPAT
ALTPYQAAVLDAVRLPRPVPAGA
>A0A5B7ULR8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MSNEEKYLDYLRRASVDLQEVRGKLREAEEREAEPIAIVGMSCRFPGGVRSPEDLWRLLL
DGRDAVSAFPTDRGWDLESLFDDDPDRQGTCYTREGAFLHDAADFDPGFFGISPREAAAM
DPQQRLLLETSWEAFERAGIDPNALRGSRSGVFVGTNGQDYLARMATGAPEGYEGYLGTG
NAASVLSGRVAYSFGFEGPALTIDTACSSSLVALHLAVHALRHGECPLALAGGVTVMSTP
GVFIDFSRQRGLAADGRVKAFADGADGTGWGEGVGLLLLERLSDARRNGHQVLAVIRGSA
VNQDGASNGLTAPNGPSQQRVIRQALAGARLSAAQVDAVEAHGTGTKLGDPIEAQALLAT
YGQGRPAGRPLWLGSIKSNIGHTQAAAGVAGVIKMVMAMRHGVLPRTLHVDEPSSHVNWS
AGAVELLTESRPWPETEQPWRAGVSSFGVSGTNAHVIVEQAPEAEQGTASEPAYGGGPVP
WVLSARSAEALRAQAALLRSFVEASAELSPADVGRSLVSSRAVLEHRAVVVGAERNELLA
ALEALAEGRTPGGVVSGVADEPGRVGFLFSGQGSQRLGMGRELAGRYPVFAEALDQVLAE
FDPSVREVLLGDDVEALNQTGVTQPALFAVEVALFRLLESWGIRPDVLAGHSIGELAAAH
VSGVWSLADAVKVVSARAGLMQALPAGGAMVAIQATEEEVAADLPETVGIAAVNGPSSVV
ISGVAADAEAVGERWREAGRKVTRLKVSHAFHSPLMDPMLDEFRTVLDGVSYEAPAIPIV
STLTGARASAEDLASPEYWVRHVRESVRFADAVGTLAGDGVGTFVEVGPGGTLSALGRES
APEAAFVPVLRGDRPEALAVTTAAGQLHVRGARVDWEVFFTGRGTRPVDLPTYAFQRERY
WLDAVPADAAVEALSPVEARFWGVVEDGDIADLARTLDVSSDAPLSAVLPRLSAWRREQQ
GRTAVEGWRYRVEWRPVAAASRHLDGTWLVVAPTGEDRAEWVRDALARNGAEARVLRVDP
EAVDWAERLAEAPAVSGVVSLLALADAGASVVPAGVGATVGLLRALGADGAPAPLWCVTS
GAVAADPADTVAGFEQSMVWGLGRAAALEEPGRWGGLVDVPEALDESAGDLLASVLAGTG
GEDQVAVRGDGILGRRLVPAPLGQASGAGWTPRGTVLVTGGLGALGGHVARWLAAHGAEH
LVLASRRGAEAEGAAELEAALVESGARVTFAACDMTDRASVAALLAGVPALDAVVHAAGI
ERSALLADVDPADPGGFADVLAAKAVGARHLHELLADTPLDAFVLFSSISGVWGSGAQAA
YGAANAYLDALAEHRRATGLPATAVAWGPWADGGMVANAGRDAAAQLRRRGLPSMAPAVA
IVGLATALESGDGNVAIADVDWERFAGTFMAQRPSPLLSELPQVRAAFETAAVEQGSSAL
AQRLAGLDEAEQERQLTDLVRYEAAAVLGHASGDALPATRAFRELGFDSLTAVELRARLN
EVTGAALPTTLVFDYPNAAALAAHLRDELCGAAPAAPAPVTVAGVSDEPIAIVGMACRFP
GGVTSPEDLWRVLLAGGDAVSDFPADRGWDLEGLYDPDPDSVGTSYSRSGAFLSGVSAFD
AGFFGISPREALAMDPQQRLLLETSWEAFERAGIAPDSLRGERVGVFVGSNMQDYGWVLA
GATEDVGGYAATGNAASVASGRLSYTFGLEGPAVTVDTACSSSLVALHLAVQALHKGECA
MALAGGVTVMSTPSSFIEFSRQRGLAEDGRCKAFGAGADGTGWGEGVGMLFVERLSDARR
NGHEVLAVIRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLTTSDVDAVEAHGTGTK
LGDPIEAQALLATYGQGRPEDRPLWLGSVKSNIGHTQAAAGVAGVIKMVMAMRHGVLPRT
LHVDEPSPHVDWSAGAVELLADDRRWPAVDRPWRAGVSSFGFSGTNAHVIVEQAPEAEQE
TASEPAYGGGLVPWVLSARSVEALRDQAARLRSFVEASAELSPADVGRSLVSSRAVLEHR
AVVVGAERDELLAALEALAEGRVSGGVVSGVADEPGRVGFLFSGQGSQRLGMGRELADQY
PVFAEALDEVLALLDPEVRAVLFGEDAATLNETGVTQPALFAVEVALFRLLESWGVRPDV
LAGHSIGELAAAHVAGVWSLADAVKVVSARAGLMQALPSGGAMVAIQATEEEVASDLPET
VGIAAVNGPSSVVISGVAADAEAVGERWRAAGRKVTRLKVSHAFHSPLMDPMLDEFRRVL
ESVSYEAPAIPIVSTLTGARSSAEELASPEYWVRHVRESVRFADAVSALAGEGVDTFVEV
GPGGTLSALGQESAPDAAFVPVLRGDRPEAVAVTAAAGQLHIRGVRVDWEVFFTGRGTRR
VDLPTYAFQRERYWPDVLPLFGDVSAAGLGAAEHPLLGASVALAGTDGALLTGRLSVRTH
PWLADHAVMGSVLLPGTAFLDLAIRAGDQVGCDLVEELTLEAPLVLPESGAVRVQVWVGA
EDASGRRELTFHSSTGDMDERAWTRHATGVLRAGGRSEGDALAAWPPAGAEAVDLDGFYE
AMADGGFGYGPVFQGLRAAWRAGGEVFAEVALPEGVKADGFGLHPALLDAALHATGFTGA
ADATGKLPFSWSGVRLHAAGATALRVRLAPTGPNGVSLTVADASGAPVATVDSLVLRPAA
PVRAAADDRDDALFGVDWVPVPLSDDGAPAVEWTTDLADLARSAAAELSGFVALACPVAA
TEDPAAGAHEAAAWALAAVRTWLADERFGTARLAVVTRRAVAPADDEDVPNLAHATVWGL
LRSAQSENPDRIVLVDLDEEAASVDALPSALATGEPQLAVRSGAASAPRLARARRNVVDD
PGFGPDAVLVTGATGTLGGLVARHLVAERGVRSLLLVSRRGAAAQGAEALREELTAQGAD
VVLAACDVADREALAALLARHRVSAVVHTAGVLDDATIGSLTPERIDAVFRPKVDAAWHL
HDLTRDAGLSAFVVFSSAAGVFGGPGQGNYAAANTFLDALAQHRRAQGLPATSLAWGLWD
TADGMAGSLDDTDVRRITSGGALPIGPAEGLALFDAAGSTGRALLAPVPMDFAVLRRQAR
TQPVFHLLRGLVRNTARRTADPASRSALAQSLAGLTESEREKALLDLVRTHAAAVLGHSS
AHAVEPDRAFRELGFDSLSSVELRNHLNAATELRLPATLVFDHPNPAALAAFISAELAGA
PAVAAPAPTAVAVTDEPIAIVGMSCRFPGGVGSPEDLWRLVLDGTDAISEFPANRGWDVD
ALYDPDPERTGTSYTREGGFLHDADLFDPAFFGISPREALAMDPQQRLLLETSWEAFERA
GIDPNSARGKAVGVFAGVMYHDYVSRLRSVPEDVEGYLGTGGSGSVASGRVAYALGLEGP
AVTVDTACSSSLVALHWAIQALHKGECTMALAGGVAVMATPSTFVDFSRQRGLSSDGRCK
SFSDSADGTGWGEGVGMLLVERLSDARRNGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQ
RVIRQALASAGLTTSDVDAVEAHGTGTTLGDPIEAQAVLATYGQDRPADQPLWLGSIKSN
LGHTQAAAGVAGVIKMVMAMRHGVLPRTLHVDEPSSKVDWSAGDVELLTEPRPWPETGRL
RRAGVSSFGVSGTNAHTIIEYAPDDDRAPAPADGVVPWVLSARSEEALREQAARLRERVA
AEPRLGLPDVGYSLATTRSAFEHRAVAVGDDRTALLDGLTALAEGRQSPGLVAGSVAVGG
VGFLFSGQGSQRLGMGRELAGRYAVFAEALEQVLAQFDPQVREVLFGEDADALNETGVTQ
PALFAVEVALFRLLESWGIRPDVLAGHSIGELAAAHVAGVWSLADAAKVVSARAGLMQAL
PEGGAMAAIRATEAEVAPELPQTVGVAAVNGPSSVVISGVAADVEAVAERWRAAGRKVTE
LRVSHAFHSPLMDPMLDEFRTVLDGVSYAAPAMPIVSTLTGVRATAEELASPEYWVSHVR
QSVRFADAVSALVDEGLTTFVEIGPGGTLSALGQESAPEAGFVPVLRADRTEESALTSAL
AQLWTRGVRPDWEAFFAGRGARRVDLPTYAFQHRRYWLDAGVGAGDLDAAGLGSAGHPLL
GAIIDTADSDEELFTGRLSLESHPWLAEHVIQGSILLPGTAFLELAVHAGDRVGCAAVEE
LTLEAPLVVPERGGVRVQVRVGGADDSGRRTVTVHARGDDADVWVRHASGALVAAPDVPP
ADSAAWPPADAEAVDLDGLYDRMADGGFDYGPLFQGLRSAWRTGDAVLAEVTLPDGVDAG
GFGLHPALLDAALHAIGLMGDADGPGRLPFSWSGVRLHASGATVLRVRLAPTGSDGVSLT
IADGTGAPVATIDSLVLRPVSGTVSRQAWESLFRLDWVPAAAASGSARSVAEFTDWAALR
SALEAGETLPENAVVHCAEPHGTDAVRHQVHAALELVRGWLADERCAASRLVLVTRGAVA
VAAEDDVPDLAAAAVWGLVRTARAENPDRVVLVDVDDADGWKAAVGSPEPELAVRAGDVF
APRLVRARPAESPESAESGFGEGAVLVTGASGMLGGLVARHLVVRHGVRRLVLASRRGQV
GALYDELTGLGAEVVVVACDVAERDEVAALLAEHPVTAVVHTAGVLDDGTIGSLTPERID
TVFRPKVDGARHLHELTRDLDLSAFVLFSSVTGTLGSPGQANYAAANAFLDALARHRRAQ
GLPATSLAWGLWATEDGMGARMAQTGAVGLSAEQGLELFDAVALGADPVVVPMRLDLRAV
RELPAVPPVLSGLVRTTSRRAAQAGGDPAAALRERLAALTPGERTSALTDLVCAQVAAVL
AFPGPEAVDERRAFTELGFDSLTAVDLRNRLNAATGLRLPATLIFDHPTLLDLVGHLTGA
LAADEPGGVAPLLAELSRIEASLAAIKPGDDEDDRVGARLSALLAAWRDGRADAVPQTAD
DLDAATDDEVFDLLGKEFGIS
>B8LV30|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MVSRIANPCEGNIVLLFGPQALSFDQEAFLKLRATILGSLSYRWVLDVVDELSSIWTRLV
KDIPILDVIDGGKKLKKLNNWIQSGDIDHDGFPLPNILLSPLVVITQLTQYASYLQDHPV
SGKLDKTETLGFCTGILSALAVSSSSGEAISQYGAVAVRLAMVIGAIVDGQDESSEQGPS
KSLATAWQSTNGEYELKQILNEFPDAYTSVHYDQRRATVTTSTKSIAALQKALRDVGIIA
NEVGLVGRFHSHSNQESLKSVIDFTNTHPGFQFPELSQLVFRTHFTTKIEDLSNMKLHHA
ALRQILVDKSEWYQLFESVQEARLSDKDSLLLSFGPERPVPPSIMRVLSSQVIHIADVNE
KVIERSDTNPYLIGENDIAVVGMSLKVAGADDVEEFWELLLKGESQHQEVPKDRVTFETV
FRDIDPKRKWFGNFIRDHDAFDHRFFKKSPREISSTDPQQRHMLQCAYQAVEQSGYFRAK
NPDKKVGCYVGVCAADYENNIACHAPNAFSATGNLKSFIAGKISHYFGWTGPGLTIDTAC
SSSAVAVHQACRAILTGECSAALAGGTNVITNPLWFQNLAGASFLSQTGQCKPFDAKADG
YCRGEGIAAVFLKKLSSAIKDGDQILATIAGSAVYQNQNCTPIFVPNAPSLSDLFRDVVG
QARLEPKQITVVEAHGTGTPVGDPAEYESIHNVLGGINRTTALQMSSVKGLVGHTECTSG
LVSLVKTILMIQEAKIPPQASFSAINPHIHHSPDHHMEIPTKVLTWNENFRAALINNYGA
SGSNASMVVVQAPFVDRSAPTVEGSKFPFWFTGPDDRTLRAYASRFIRFLNSKSVSSKNL
TLANISFNVSRQSNRNHDKGLIFGASSLQEVEQKLSCFANGGSDVNSQPKTAPRPVILCF
GGQVSTFVGLDQQLYEHVTILRQYLDQCEAIITKLGESSIFPGIFQRTAIEDPVYFQTML
FSVQYSSALAWIASGVEPVAVVGHSFGELTALCVSGALSLEHAIKMVIGRAKVIRELWGS
EKGSMIAVEGDIEQVQSLLSVSVVEGEAAATIACYNGTRSFTLAGSAKAIEGVAKTASTG
LFSSMRTKVLNVTNAFHSTLVEPLITELEKVGSGLTFCQPTIRLERAIDASPHASLTSKF
VAEHMRFPVYFNHAVQRLAQEFPSSIWLEAGSNSTITTMASRALGSSGDHHFQAISITNT
SNGITNLADATVSLWKNGLDISFWAHSCKQTYSFAPLLLPPYQFEKARHWIEMKKPSKSG
GEPTVLEVVETTIEELPKTLLTFVGYEDRDQRQPRFRINTMIPKYEELVSGHIIANTAAI
CPATVEVDLAIEGLRILYPDVTDSMQPQIHSVDNQSPICVDTSRFIWLQYQALDNAAHTW
SFKIYSTGTGKEASTTHVTGKILLRSLDDPQTHADFARLERFVNHERCAALLKADDADDV
IQGRNIYKAFSEIVNYGEQYRGLQKLVGKGAESAGRVVMNPSSETWLDAHLSDTFSQVGG
IWVNCMTDREPTDMYIASGFEQWIRSPNLRSNTKRPGSWDVFALHQKHSDRVYVTDIFIF
NGIDGKLTEVILGINYARVAKLSMSKLLSRLTAVKNTASSALPSAATKLQSGIAISASGP
VLSTNDISLPQKSPKKVKAPKKKTPSSQPDITGKVRAMLVELSGLEPEEMKEDVELANIG
IDSLMGMELAREIEDIFKCSLPEEQLVEVTTFKALLQCIRANLPDSSDDNPDVEEDDESL
ENTRVFTPSDVATSVSSARKADVTEFLVEFLGIEESIITRNTLLRDLGVDSLLSTELRAD
ISSKFGVDVPEEVMLEDLSVHEFDVQINGSSTGAAPEPEVPRASSTSGVPSTTARALGGN
LNLPASTVLEAFHETKLLTDKFIEDYQCAGYIDTVLPKQDQLCIALAVEAFEHLGVSLKG
AKAGQKLEPIKYLPQHDRLAEYLYMMLEKGARLIDIDSNGVITRTAVATPTKSSNDICQQ
LNRDYPDHNFANRLTQFCGLRLADVLTGKIDGIKLIFGSSEGRELVSGLYGDSLLNKLAY
EQMKDFLRRLISKLPMHDGPLKILEMGAGTGGTTKWIVPMLAQLNVPIEYTYTDLAPSFV
AAARQKFKNFPYMKFRVHDIEKQPADDLLGTQHIILASNAVHATHSLTVSTRNIRKALRP
DGFLMMLEMTETVYWVDVIFGLLEGWWLFEDGRRHAIAHQSRWEKDLESVGFGHVDYTDG
HRPEVNIQRIFIALASGQRYDRIPIPPKAIMHEAPKTDIGAREAAVNKYLQKAVSGFTAV
PISYTPYPVLLNQGVLVTGSTGSLGSHLVAHLANLSSVKTVFCVNRVSRSDALKRQQDAL
LSRGISLTPEALSKLVVIETDTHKPFLGLQRDSYDRIVHAVSHIIHNAWPMSGKRALMGF
EQQFVVMRNLVNLANEASTSGPRKITFQLISSISTVGYYPVWSGKRLVPEMRVEMNSVLD
NGYSDAKLVCERMLDETLHKHPDRFRPMVVRLGQVAGSSTSGYWNPMEHFSFLIKSSQTL
RAFPALEGELSWTPVDAVASTLGDLISGDHRPYPVYHIDNPVRQQWLDTIPVLVDALGIP
QSNVIPFKEWVGLVRRFPGSEVDNPAVRLIDFLDDNFLRMSCGGLLLDTTKSLKHSLTLA
AIGPVSGDVARKYIQAWKDMGFLH
>A0A5B9QYS4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Roseimaritima ulvae|TrEMBL
MSDFSERIANLSSDRLSLLAIELRAKLEEVEANRHEPIAIVGMSCRFPGGADVDNYWRLV
AEGQDAICQIPSDRFDIDRYYDPSPQTQGRTYARHGGFIQEPLLFDAGFFGLSPREAESM
DPQQRLLLEASWRALEDAGLVPAELVGSATGVYVGLSTDDYMQLSCRHGGLDQINPYTGT
GCSGSVAAGRISHFYGFEGPNLPIDTACSSSLVGVHLACQNLRDRKCDLALAGGVNVLLA
PDPFIYFCKVGALSPDGTCKTFDASANGYVRGEGVGMVVLKRLSDAVDAGDRILAVVRGS
AINHDGRSGGLTVPNRRAQAAVIRDSLADSGLDVSDVDYVEAHGTGTRLGDPIELRALGE
VYGEGRPADDPLLVGAVKTNIGHLEAAAGIAGLIKAVLMLRHQQLAPSLHFQQPNPFVPW
NELPIEVVAKNRDWPQRDRPLRAGVSSFGFSGTNAHVIVEQAPHATAAEDAFSNGATTIG
ATTIHSAGNGAVRNGSPVTAVAPSHHLLCLSARCEQALREHAANVAATLSSPNPPSLADV
AFTLNTGRSPFERRLTVVAATPAEAAESLQAYARGEAAAAIVPSEASEDDRPKIAFLFTG
QGAQYPGMGKDLYDSEPVFRQTLDECAEVLQPLLEHPLLEVMYGDRGDLLDQTCYTQPAL
YALEYSLAKLWQSWGVTPSVVMGHSVGEFVAAAVAGVLDWKDGLRLIAERARLMYALPEG
GAMAALFLSEAQARAAIAPHGDALSIAAINGPSNVVISGQQAALDAVLKQLAEQQVKATR
LSVSHAFHSSLLDSMLPELEQFAGGFEHRDAQIDMVSNLHGRLVRTGDITPAYWSEHARQ
PVLFEAGVEVLAEQNCNVMIEIGPGTTLLGMAQACRDAGTTSPAVRSLQSLDRAGNDEQA
LLQSLQNLHAASAALTWPRRGGQLTSLPSYPFQRQHMTLDFSREWVPADQLGTQSAPLPR
PATSSDQDVDNDSDNARSGADSVEQWLYDIYWDKVEIPAKSGRTQPGHWLLLGGSGELAD
RLEQQLLERGATCCRPALDASSTAAFDELLEQLATADTPLTGCIHLASLEATDQTEQAAV
MQACAGALHLSQALLRRGVMDFEHWFVTRGGAAINDQDIAGLRPLQAVFGGMGVAVAVEQ
ERWFCSQIDLASDMNAEESAAALTRLVTARERENRHAVRSGRRYLARLKRRPDAYSAQTP
TINPDGTYLITGGLGELGISLAQWLVDHGARHLVLVSRRTPNDDALAAIAALQQFGAQVT
VRSCDITDSAAVNELIAAIEQQGPTLRGVLHCAGVNLAELIPQLEWSQFENVLRPKVTGT
QNLQRALAGKPLDFNVYFSSMASILPGPGQTAYGAANAFLDAQARLDAANGQHGIAINWA
PWAEAGMAKRLTGSLRRRWKALGMPELVTADALAAMSAVLSTKPTQVAVMPFDWNKLFPI
YPPGLEPPILKTIAEQERKQEPPSEVWLRLAEQIRKAAPQQQTSLLEQYVEAQVAGLLGH
DGEEAISRTAGFFDLGFDSLMMVELRNRLQTDIGFMYSLPATVLFEAPSIRQLAGYLQEN
VLQTGTTATPVAARARTLDEPIAIVGVGCRLPGQANDVQQFWDALQAGRDAIEVVPPERW
DIDEFYDSDPNTIGKMYAREGGFLKNVDRFDNSFFGISAREASRMDPQQRLLLEVVWEAL
ESSSTPVDQLPKQKTGMFVGISGNDYVRLLAQNGDPAALDAYLGVGNALSIAAGRLSFFL
GIQGPTMALDTACSSSLVAVHLACKSLRDGDCNVAFAGGVNLILTPETSVSLCKAQMLSM
DSRCKTFDAAADGYVRSEGCGAVMLKRLSDAVADGDEVLATIRGTTINHDGRSGGLTVPN
GQAQKDLLHAALADSGLGVNDVDYVEAHGTGTRLGDPIELRALGEVYGEGRTADDPLLVG
AVKTNIGHLEAAAGIAGLIKTVLMLRHQKLASTLHFQQPNPFVPWNELPIKVVDENRDWP
HRDRPLRAGVSSFGFSGTNAHVIVEQAPPVASAVESPTVKSSATDAKATVPAPRRSRHLL
CLSARCEQALREHAANIADTLSADEPLSLADLAFTLNTGRSPFEYRLCLLAESPAEAATS
LQAYSRGESAPALVAGETLDNDRPKIAFLFTGQGTQYPGMGKDLYDSEPVFRQTLDECAE
VLQPLLEHPLLDVMYGDRGDLLDQTRYTQPALYALEYSLAKVWQSWGVTPSVVMGHSVGE
FVAAAVAGVLDWKDGLRLIAERARLMYALPEGGAMVALFLSEEQARAAIAPHGDALSIAA
INGPSNVVVSGQQAALDAVLKQLAEQQVKATRLSVSHAFHSSLLDSMLPELEQFAGGFEH
RDAQIDMVSNLHGRLVRTGDITPAYWSEHARQPVQFEAGVRALLEQDCNVMIEIGPGTTL
LGMAQACAASDDVQWLPSLRKSAAASAGLLPSLQRLFVAGAPVDWKGFHAGEPSRHVALP
FYPFQRSRHWLADTRVSPPPAGLVPGTLAVDSSPLAGTQDNPPVDGSNSGAVSASASSLT
PPSEGAAAAEDSLLIGSTGIEAFGEQKLTSPAFNDEIYQFKISSNRPALLDDHRIYTMAV
VPGAFHVATALTVMEQRQDYPLHLQSMAFPEALILPDDEMHRLQLVMTPTDEGHDFRVFA
NRMAEDNDGKWTLHAAGKMADELDDPQAVAPAIDEVQARCTQHLGSSEVIYRYMYQQGLH
LGNHFRWIDEIWLRPGESISRMRCSQHGEGSEGPFVLHPGLMDSCYQTLGATFVTSENDR
SAYIPINIERLTILRRPTKPLWVHAKLRDMGTDPKNAAGMVGDLVVFDEDGVVIVIHGLR
VRRASHAALRRFANKQVLDSVYSVEWRQTDMPSTRPADKAKWLIFGNRDATTNQAIETLT
RDDPQSECFVVYPDGQSANGQDHLAAPPRAQSAGAIDPDRAESYEAVLNAFPDTQQWRGV
IFLWSASQRDSSVQSWETYLQQQQTESRALLYVVQSLHKKYGMSVPRLWVLTRGARAVDE
REQPDVGRAGIWGMCRVLALEHPMLRCVRIDLDGDQQAVSPFDKIFWATDREDEIAFRGG
QRYVARLSKSKMKSSAGRMTADSAQRLARSPDGRLNGLSIVPASRQTPREGEIEIRVAAS
GLNFRDVLNALGVYPGDAGPLGGECSGHVVAVGPGVEGFEIGDPVAAIGMGTFASFVTTP
AVLAVRLPETVDLLQAASVPVAYVTSLLCLDQQAKLKAGDSVLVHAGAGGVGIAAIRYAV
QLGAKVYATAGNDEKRALLKAEGVTGVFDSRSLDFSKQLLQTTGGEGVDVVLNSLAGDFI
PASFDVVKRGGAFVEIGKRDIWTHQRVREYRPDVNYHIVALDELIQNDPPQVGRLMAQTY
QLINSGACDVPPMQSFGFEQAAEAFRFMAQAKHIGKIVLAMSDEQTAARQAHVRDDANYL
ITGGLGALGLHTAGWLVSQGAKHVALVSRRGANTAAAPAIEALRARGATVTIHQADVSKR
DDVKRLVDELNNGVPLRGVFHAAGVLSDKMLVNQDWDSFVDALAGKVGGALHLHEQTQDL
ELDYFVMYSSAAALLGFPSQGNYAAANATLDALADHRRARGQAALSVNWGPWAEAGMAAN
ASDRVQQQWSTLGVNQMTPKQGIAALAFLLEENAVNLAVMDIDWTRLLRRFPESLEPPLL
STMADSGGNALEPSKEWLSFVKQVSEAEPEQRKRMVVAFLQSNAGRILEAPDDQLPAATT
PLNEIGFDSLMLVEWANELGAATGTSFSATTLFDYPTIDALAGYLLTDVMKIESPAESSK
RETRVTKTASVDDLMDSIEGLSDDEASRKLRGK
>G0Q189|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MSTAAPQPAADDVAIIGLALRFPGAETLEELAGHLLAGRSLISEVPPERWSREEFFGDPR
RGAQKSNSVWGGFVEHADRFDADFFAISPREAESMDPQQRMALELAWRAVENAGYAAGDL
AGTATGVFMGVCHADYAEMMEREGVRTDAYFPTGTAYSIIANRISYQFDLQGPSITNDTA
CSSSLVAVYEAVRALGHGECGLALAGGVNLIWSPKHFVAFSQAGMLSRTGRASAFDQAAD
GYVRGEGGAVLLLKPLARAVADGDPVHAVIKGVATNHGGRTNSLTVTSPTAQANLIEGLY
TRAGIRPETVSYIEAHGPGTPVGDPIEVMALKTAFRNLHAAQGTAARPESCGIGSVKTNI
GHLEGAAGVAGIAKVIASLAHRSLPATVNFRQQNRLISFDDSPFHVVRETRPWEAPPAGP
DGSVPPRRAGVSSFGFGGTNAHVVLEEHLVDEPRRTDPPGPHLVPLSARTPERLRQVART
LLTHLREQPAQALADIAYTLRIGRDPMRERVAFIVADRAELVGLLAAFADGERAGGEVHR
GATVRADDADAAGLGTAAALWAGGGTADWAERLREADPAAAPRRVRLPGYPFARERHWFR
VPPKDGDAGIPREREAGTPGEGEAGRATADRSPAPTAPTAPTAPTAPTAPTAQTAGTANA
ARTEPARTGAERALTEQPGAASRSAAPHPLLHAAVPGSGGRRFTSTFTGKEPFLAAHRVR
GTPVLPAAAQVEMVRAAVARAAGRETGAPPAVRLRTMGWARPLVVRDGPVEVRVGLTERD
GGALAFEISTGTAPGTVHSSGLAETVGAGEPARLDLAGLLAACPRERGQAQVYAEFRDRG
LDYGPAMRGLRELRLGQGQLVARIVEPGADGAGDAGHVLPPSVLDAAFQASVVLLADTST
ATGGGRSAPALPFAFEELTVHGPCAPETWAWVRRREGRGPLDMFDIDLCDGKGTMSVSLR
GLVQRTEPAGATPGAGPETGGNTVTAAVSWVPAPLGVPDDGAGPVPVVRGYLGGRAARHT
AAVADLTGFTVARLPDVDPGRVAEGAGAALDLAFRDVADAVRSKPAGPRRFVVLVDDRPP
RHYHAPLTGLFRTVVQENPRVSGRVVRVADLDAAPPERIAEILRAEAADRSADCDVRYGA
DGTRHASRPGELHLGDGAEVPPLKEGGVYWITGGLGGIGRHVARYFGRYPGVTVVLSGRS
EHGAASEAALRELRDAGVDAHHVPVDVGSRTDVDRAVRAITGAHGGIDGIVHAAGVLRDA
YVFTKDASDLRAVLAPKVDGVLHLDAASRGLTLDFFVTFSSVAGVFGNAGQSDYAAANAF
LDAFAHHRQALVDIGERTGRTRSVSWPLWADGGMSVDAVTLRTMRRDRGWEPLPTEDGLR
LLGRVLGDAPPHVVVAHGAAATLTAAPTPPAAPTVPDPPAAGSGASAPAAPAPAETAATV
ADEVLRERATALLRRVVGEALHRDPGTLEETVDLIEYGIDSLAILDTTAALEELFGPLPK
TIFFEYTDIAGVAGYFVAEHAGVLRTVPDTASPHRTTAGRTAEATVPAEATAPVGGTVPV
AAPVVASLPAAPERPVAEAAPASARSRSEAPGARDDYHDIAIIGVSGSYPGADTLDELWA
VLEEGRHAFREVPRDRWDHDAIYSSDRGVLGKSTIRTGTFLSDIDTFDPRYFRISQREAE
NMSPEVRLFLRAGVEALEDAGYSRETLRRKYDGDVGVLAGSMSNHYGLYGFENGLTRGSA
ASGSYTGTLPNMLSYFYGFTGPSLFVDTMCSGSSTCVHQAVQMLRARECAMAVAGGVNLL
LHPYNLISSSQEHFTTATSDVIRSFGLGADGTILGEGVGALVLKPLVEAERDGDHVYAVI
KGTALANAGVRNGFTVPSPRMQARAIEKAIDDAGVDPRTISYVEAHGSGTSLGDPIEVKA
LTTAYRKHTPDTGFCAIGSVKSNMGHLLHAAGMIGIAKVLLQFQRGQLVPSLHSSVTNPD
IDFSRTPFRVQQELTAWKPAVTTVDGREVTHPRRAGITSIGAGGMNSHMILEEYPRHDGA
ARGSAPGGREELLVFSAMNDAALLAYLARFRAFLAKAAAPDLASVAHTLRVGKNELPHRW
AFLARTVDEALAAVDRRLAGDRDLGAALAGDGARTADLRDLATAWVGGSSADWQRADAQD
APAPRRVSLPAYPFERVRCWVAPQDGAPSVTAPLALREKLHPFLGRNASDVTGLRYVLDV
HLDDLLDYGRTLGERQDRTRGIVPTFAADLAIAAAKVSGFSDGSLVRGLRLLGPVDWTAA
ARLVTVLDTAGGDSAAGAVHTEDASGRRTAVAEFALRADGGGGTRPTGHPHAGPFVGLLP
GALAPDLAEPLSPAVFLAELAGGGVGYAPELAGVEEVFRLRDGRLVLRLGTPELQHDRVK
PRVTLAPQVLQAVAQGLRFEAKRTGDPRWARSAPHRIDEVRIFADGADGRVPVAYAVFDV
TASGEGIGGSVGLLDRNGGVVGVLAGLWCGDDEGPREDPEVTARTSGATTAGARGGNGQA
DDGTPGETGEAGRLLAFAVDELRGLASGILKFDPGELDARTGFDAFGFDSISLVALASQA
SERLGVELTPAVFFDRSTLASLGEHLVAEHAATLRTAYEQSTGTPARADAPATAVRTSGT
SAGTPRTSGAPRPPAPETGHRTRRESAGAPDAAPRPADPGGAFPIAVIGASGRFPGAPDL
DAYWANLAAGTDQVTAFPVDRYDEEYARIVEASDFPRHAGVLDGVDAFDAAFFRILPREA
ELMDPQHRLALQTVWNAVENSGYAPADLPAGTGLFFGVSGTDYATLLAAHGTPPDAFTST
GNAHSMLANRISYVLDIHGPSEPVDTACSSSLVAVHRAVEALRSGACDAAIAGGVNLLLS
VDTFVSAAQAGMLSPDGRCKTFASDANGYVRGEGVGAVVLKPLAAAERDGDAILAVIVGS
AENHGGRANSLTAPNGAAQADLVVRAMDGIDPRTIGYLEAHGTGTPLGDPVEVQALRNAF
RRLGSDGEGTCALGSVKPNIGHLEAAAGIAGLLKTVLAMEHGTLPPSRNLDEINPYIQLD
GSPFRIVRACEPWERATDEHGAPVPRRAGVSSFGFGGANCHVVLEEYPGRDQEAAADPDA
PGGRRVAVPLSARTERELRERARDLLAHLEDARRTDSLRSIAWTLQTGREAMAERVGWAV
ASRGELVSRLREFVSGSGDGPDPVPGQDRDGLTGMMARWCAGGEAEWRRLYGPDGSGTPR
RAHLPAYPFARDRYWIPRSPEPSAPTRSHAAGPERAVAVPAREPAPVPAPATTLLVPRWT
PRPAAGAPGPADGSPYRRHAVILCGTPASLREGVGRLLPGVRCHAVTTAGRRPETRFTDL
SRQVFQLVRTLAGEAHDGTTLVQVVTSGAEDEEAGPALSALLRTTALENPQITGQVILLD
GASDPARIADAVLENARHADDPLVLHRDDERHVRTWTPRTAAGAGTPWRSGGTYLITGGA
GGIGAVVARRIARDTERAELVLVGRSAPGPRTDRLLAELREAGAAARYAVADVSRWEEVR
HLLAEVRERSGAVHGVIHAAGVIHDAYVKEKTPEEWEWVLGPKVDGAVHLDRATGDLPLE
SFLLFSSGAAVTGNPGQADYATANAHLGTFAARRNARVAAGGRSGRTVSIAWPLWKDGGM
AVDDATRAYLRRHRGLVPMEADAGLDALLDAWRLGEAGEDQIWVHHGDPERAGPDPVAAS
APRSAPAPAPVAGTAPAPASVPDTVNGVAPDPDTLRSVLGIFARVTKLPPHAIDLDRPLD
ELALDSVMVVQLNRELHTVFGETSTTLFYEAPTLRAVADHLTGPPIRTGRETATAPGVPE
APRSAAPRSAPAPSGAPDRDDAIAIIGMSGRYPGARNPDEFWQNLTAGRDRITEIPGDRW
PLDGFWEPDRATAVANGLSYSKWGAFLEDFDAFDPHFFRIAPRDAYAMDPQERLFLQASW
EVIEDAGYTREELARRHQRRVGVFAGVTKSGHARHGEARLPSGERIAPALSFASLSARTS
YVLDLRGPSLTIDTMCSSSLTAIHEACEHLRRGSCELAVAGGVNLYLHPSDYVELCRSGM
LSSQSRVRSFGRGADGFVPGEGVGAVLLKPLARALADGDRVLAVIRGTSINHGGRSNGYT
VPSPAAQAELIGEALTRAGISAREVGYVEAHGTGTELGDPIEVKGLSLAFEKFTGDRQFC
AIGSVKSVIGHLEAAAGIAGVTKAVLQLRHRTLVPSLHAEEPNPGIRFEETPFRLQRALV
PWESARPRVTAVSSFGAGGSNAHVIIEEYVADAAPAERSADDGEQLVVLSARTAEGLRLS
AARLAAFLEQEEAHGRTVRLADLAFTLRSGREAMRERLAVAVPSVPELRRLLDVFAETGD
GTAVPGLHRGGTGQDRGAAAAIRADGDLRELLAERWGRAGKYGELAALWADGMDLDWRAL
PGAVPPPRRISLPTYPFARDRFWIGDLEPAGRPIATGAPPHADTGPGDRRVAVTGTPADD
VTPRTAPGGPAAVTPRTAAEPRDPAGTAPGERLARLVRAKIADVLVMAPEEIEGGLAFAD
YGLDSILAVRLVHVLNEELGTDLSTDVVFDHSSADRLAAHLLAEVGPAAAPAPVPPPPAP
VPPPPAXXXXXXXXXXXXXXXXXAPRRHAAARPRTARRPPTEPPPPDRRPAPNRSPS
>G3J032|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Methylobacter tundripaludum (strain ATCC BAA-1195 / DSM 17260 / SV96)|TrEMBL
MKSIDALMSRLRELNIKLWLDGDQLGCRAPKGVMNAELAAELSAHKADILRYLHQAEAST
ASQQNSIPAAPRNQLLPLSFGQQRLWFLEQLEGPSATYNMPLAMRLEGTLGVAALEKALS
EIIRRHEALRANFKIEDEQAVIRIRETAECPLTVVAAKESGTGEEQRWIQQEARRCFDLA
NDPLVHATLVQWTDSSQLFLLTMHHIVSDGWSLGIFLRELAALYEAFSNGLPSPLPELSI
QYADYAHWQRQRLQGKVLDQLLDYWRQQLSGAPELLALPTDRPRPPIQTYHGRSLNAKLD
ADLSKRLQTLSQTTGGTLFMTLLSGFALLLSRYSGQEDIVIGTPVANRNHTDIEPLIGLF
INTLALRLDLSGNPSAQELLAKVRNTCLEAYEHQDVPFEQLVEELKPPRSLSYAPLFQVS
FDLQNTSMDAIVMPGLSLCPVEQEAVAAKFDLSLSVEETATELLTVWNYNPDLFDEATIV
RMMNHYRMLLEGMVAEQAACLGELPLLDERERQQILYAANATAQSYPAAHSFLDLFEAQA
QATPDRIALSFADQSLSYRQLYRRVRQLASALQMLGVGPEVLVALCVERSVDMVVGLLGI
MRAGGAYIPLDPGYPPERLACVLDDARPLLLLTQERLEAALPASGARVICLDRDREMLAD
LAQQNPHGPVPPAGSNAAYVIFTSGSTGRPKGVQIQHRALLNFLVSMQREPGLSEQNALL
AVTTISFDIAALEIYLPLISGAHLVLADRETALDGRQLQATLQSHRITHMQATPATWRVL
LESDWQPRTPFCVLCGGEALPVDLARQLLQKGVRLWNLYGPTETTIWSSAREVVSADPSK
EGVEAIGRPIQNTQIYILDKYNHPLPIGVAGELHIGGDGLARGYLYRPDLTADSYRPDAF
SDRAGARLYRTGDLARRLADGTIDFLGRIDHQVKIRGYRIELGDIEAALRQQPGIKQAIV
LAREDLPGDKRLVAYLLATIEPAPSTDELRTRLKTGLPDYMLPAAFVFLDAMPLTPNGKV
NRNALPAPDLARPELNAGFAAPRNELENSIAEIWRQALRLEHVGIDDNFFDLGGHSLLLT
RVYESLRKQVSEPFALITLFQHPTIRSLAARLAQDEIPTPIRIRANTSRNADSSDEIAII
GLTGRFPGADDLETFWDNLREGRESIRFFTDEELLDSGIEAELIALPNYVRANGMLSDVA
GFDAAFFGYTPTEAEIIDPQHRLFLENAWHTLEHAGYGAYTRDTAIGVFAGCSHNGYLLR
NLMPHLYTSDAHSIYQVMLGSDKDFLSTRVSYALDLTGPSVSVQTACSTSLVAIHMACRS
LLDGECDMALAGGVGLKIPQKSGYVHQEGMINSPDGRCRAFDAGANGTTWGSGLGIVLLK
PLHAALADRDTIHAVIKASAINNDGALKIGYTAPGVEGQAEVVANAQARAKVAPDSISYI
ETHGTGTHLGDLIEIAALTQAFRAGTDKNRFCALGAVKTNIGHLDAAAGVAGLCKTVLAL
QHRQIPPTLHFERPNPEIDFENSPFYVNDRLRDWPSNGAPRRAGVSSFGIGGTNAHLIVE
EAPEPSASLSARPWQVLVLSARSHNAVDNLRTSLVAHLQEHADLNLADAAYTLGLGRRQF
AHRIAVVCRDRQDAVTALQTPERYRLGHIPKTQTEDRSVAFLFPGQGSQYVAMGADLYRT
EPVFREHIDYCAERLIDELGLDLRHILYPAADNAEQAAIQLEQTWLTQPALFVTEYALAR
LWMSWGVKPGAMIGHSLGEYVAACLADVFDLDTALILVARRGRAIWEQPQGAMLAVSLPV
DKIPALLGDDLSLAAINAAEACVVSGPFPAIEALEIRLSNSGIACRRLHTSHAFHSSMME
PAVAAFAEALDSLVLKPPRLPFISNLTGTWISSEQATDPGYWARHLRLAVNFEAGIGTLL
SEPDRVLLEVGPGTILSNLARRHPLAGNTRCVFTSLQQPNTAETQNMLDSLGRLWCAGVS
IDWPAYYAHEQLGRIPLPVYPFERQRYWIDAPAGDALPLMQNLQKKRPLDEWFYLPGWKP
TLTPRALHNDDFTEQSLWLVFSDESALSRQFIAKLQQAGQDVITVCQGEAYEQNGADYRI
NPVSPDDYATVIQSIGDRPVHKILHFWSLSATDTSGPEVFEQAQQNGYYSLLFLGRALAK
QSQSGKTSITVISNHLHDVNGLGESIPEKTTLLGPCLVMPQEMPRITCRCLDVVLPVANA
NGTADLVNLLLAELENGASDPWVAYRGSRRLVPGFERVPLSAAADSVRQLRRHGVYLITG
GLGNVGLLLAKFLAETAQARLILLGRSFFPARSQWDDWLQSHPADDELSVKIRAIQHLET
LGAKVLLIQADVADEKSMQAALAQAHDQFGALHGVIHAAGRLNDASFVSAFTDIGRRESQ
VQFGPKIHGLYVLEKLLREQHLDFCLLISSTAAVLGGVGFAAYSAANLFVDAFAVRQNRA
GGTPWLSTNWDAWLFADTPASEALSMQPKESVEAFRRVISQVFSGRIIIATGDLQTRFKQ
WVGLEKRLEKPASDSLYTRPELSSAYAAPTSNSENQLAELWQDLLGFADVGIYDDFFELG
GDSMLAIRLISGIKEKFGRQLPLTSLLDKPTIHQIAEALDRPEETLTFSPLVVIQSKGSL
PPFFCVPGTGGSVLYFNELARCLAEYDRPFYGLQALGLDGFTPPLTRIEDIAALNIGALQ
KVQAQGPYYLGGHSFGSWVALEMAQQLQKAGHEVALVTILDTGAPSERDLSAIGGWDDSR
WLVAVADTLGHLYEKPLSLSYEELVDLPWSEQIDLLASRLSTRGVTEQGTASTEIRGFIE
VYKTQARIHYRPDPDCPVNIALFRAREPLADFLDGMPEYLKNDETWGWRQCSKGVPVMEY
IPGDHLTMVTQPHVRRLAQRLHLALSLARGD
>G3J034|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Methylobacter tundripaludum (strain ATCC BAA-1195 / DSM 17260 / SV96)|TrEMBL
MDTMVTALVNDPAVEEYFVLERKTQHGEVEQVAYIVTTEPHRFEQAQLRLQALSEGQIAW
FVAVAYLPLNDDGTVDESALADVPVLAEESAAECAGRIATLPNIERVACISGYWPDSPKY
IHVGKLLRNQIPNAALPHAETPLPSARGNEPAPDAICHGQPLPQRDGAAQVLQQVLCSAE
PGTPIIYVDSDGNERAESYGSLLTEARRILGGLRYEGLKPGDKVVFQLERNDDILPAFWG
CLLGGFEPVIVPVPLSYDIESRAVEQLQQIWNLFDQPLIFTNNSRSTSIRTSSQAPCFAD
ARWVAIEALRDNPADMHIHSAAPDDIAFYTLSSGSTGIPKAVALTHRNLLARARGTNILC
QHTADDVIFNWLPFDHIGSISEWHLRYLDLGCKLVYAPKEYILARPLRWLELMHRHRACH
SWSPNFAYALVTNALNSEPQQDWDLSCVKTLLIAGEAITRTTTREFLESLACYGLQPSTL
LAAFGMAEVCSGVTYHQPATGQSLGFHHIDRNSLSGAIRRVDPDDELCVSFASLGPVIPG
VSMRIADDEQRVLPEETIGRLQLKGDVLTPGYYHNPEANKVFLADGWFDTGDAGFISGGE
LVLTGRAGAGIIINGANFYNNEIEAVVEQIAGIAASFTAACAVRQESSEGLKLAVFFHAA
YENNDAVLLKLLKTIQSQLTKRLGIKADYLIPLDRDAIPKTGIGKIQHKKLIEQFQQGAF
QEILEHLDLLTANEQTLPDRFHKKIWRRKELVHIPRVDDDVCVIFLDRLGLGLQVASELD
TAGIQCILVKPGESFAQLGAMELSIRPNEPQHYHQLVEWLKASDIRLGSVLHLFSYDTEQ
KEADSVLLLAQALSALDLDAPLRLLAVSSHKHKGIASAKAALPGLLHAIEQDQPLLRCLH
LDCPAYTPSAYAPAIVSELLGISVDREIAYRGQQRWVAGLQQIDVATVTKESPSVLPFQH
QEVYVINGGLEGIGPQLAEYLLSRFNSRLILLGETPLQSQAAADDKDARPAHYQRLRQLS
GECVYLAVAALNQEELQQALIAALAQWDNKLDGVIHLAAALPEHPLLEETQAPKSVPELI
GANALYRILEQFQGKFFISLSSTSGFLSAPGQCSPETGIASREALATSSLGGPRFYSIGL
SDWDSLDTASALDAQTPVGSSVRRSINAILVALQLDEEQVLIGLDGDSPAVRAQTHIGPP
QLGKTAVYFTARQLMTPARLNPEPLTDRYGSIVPCDYIQLREPESAGAEQLELWPSVAEY
FVYDDLIYYALANDERRNDSYRIALQRTVPGKIVLDIGTGKEAILARLALEAGARKVYAI
EMGDEAFAQAVAYIQHLGLDDKITIIHGDATKVEIPELADVCVSEIVGPIGGCEGATALI
NNAHRFLRPGGIMIPGRSITKIAAARFPDGLLPHPGFYQVPSSYTGKIFAEVGYPFDLRL
CIKNFPRNNLLSNADIFEDLDFNRITPLEEQHQIELIIDQESRLDGFLVWLNLHTIEGEV
IDIIEHEYSWLPVYLPVFHPGIEAKPGDRIIATVSRSLCENGLNPDFVVSGQFLRCNGES
IPFTCTSYHYKQQYKQHPFYEALFAEDPLGRHPGCRPGNLLQYLPEMPLTVGGEIDRNRL
SKLTLGNTQETAQQQSPGSEIEVQIAKIWQDVLEIPQVGIHDNFFELGGHSLLLVQAHDR
LVEIFGPQITLVDLFKYPTISALVELLADEGLRETPSQKGRERAEARSNYKSTQSSTDIA
VIGMSCRFPGADDLETFWRNLAEGVESVTFFDEQDITATGIKPSVVRHPDYVKASPLLSD
VEGFDAGFFGYTARDAELMDPQHRLFLECAWEAFENAGYDPIAYEGVAGVYAGASMNTYL
LNNVYPNRDTLDIQDDLDVATLDSMGGFLLMVANDKDYLTTRVSYKLNLTGPSVNVQTAC
STGLVTIHMACQSLLNGEADLFLSGGAAVQVPQQSGHLFQTGMIVSPDGHCRSFDAEAKG
TVFGSGVGAVLLKRLDDAIRDGDHIYAVVKGSAVNNDGGVKVGYMAPSSEGQAAVAAEAL
AMSGIAPDTIGFVEAHGTGTEMGDPIEVNALTQAFRAQTEAKGFCALGSVKTNVGHLQIT
SGTVGFIKTVLALQHKLIPPTLHFNKPNPAIDFENSPFYVNTRLTPWKTSGTPLRAGVNS
LGIGGTNAHIILEEAPLSASITNDLERPQHLLTLTARTEPALLELAGRYAKFFTNNPQAS
LADVCFTANTGRRPFEHRLAVPVESAAQLREDLQSVAAGQHPDSVIRGQMSPQGRPKIAF
LFTGQGSQYPGMGRQLYDSQPVFRQQLDRCAEILQPLLDLPLLEVLYPADGSSAKLDETA
YAQPALFALEYALAELWKSWGIEPSIVIGHSLGEYVAACIAGVFSLEDGLKLVVERARLM
QALPTDGEMWVVFATEAQVRPLLTAYANDVAIAAENGPESIVISGRKQALADILARLHEG
GYKTQALNTSHAFHSPLMEPMLADFARVAGRITYTPPQIPLVSNLTGTLASDEITTPAYW
RRHIRQPVKFMAGMQALVQHGCEIFIEIGPKPTLLGMGARCVATDQGIWLPSLRQGEADW
QTLLNSLGQLSVCGPVDWKGFDQPYQRRRLPLPTYPFQRQRHWLDRPATVTTAVRGNGNA
RPLLGNKLQLPTLQATIYENRFSAEALPFLQDHRVYDEIVVSGACHVAMLLSAAAETFGK
SAYVLKDVYFPEPLIIPDGQTRTVQVVLTPTADSNATVQLISFAATATPEQPGVATHAEG
SFEQAVVRSADKSFQTLWERCGETLSTEAFFQAQADRHIHLGPSYRWIESIKRGDRETIC
RLRTPESLGGLDAKQLHPGLLDACFGLLLATGILAEDETWLPFGIEEIRVFQALDNTPMW
GHLVLRPADAAKRVIADATLCDSAGQVLIEFIGLEARAASLKAIQRYLPNRADTLLFGYD
WLPLAATSHSPSAHIQGQWLIFADSQGTAGQLAQQLRAQGARCVLVTPGSAYGIVEQDHY
CVDPDQADGFARLLQDSVGTTGRFQGIVHLWSRDETTVEDSQWLAHTQSLACASVLHLVQ
ALVHANGLGGTRLWLVSRGGQTVGNETFSPQIQQAPLWGLGLAVALEHPELACTLVDLDP
ATADADDLLASLQTADDESRIAWRQGTRHVARLTRQQVPTTDQQPSIRADASYLITGGTG
GLGLSTAAWMVAQGARHLVLTSRSKASKEALEAVNRMELAGAQVLLMQADVADREALAQV
FHTINATLPELRGIMHCAGIIDDGMLAEQTWEHFKRALPAKIHGAWHLHQLSQALPLDFF
VLFSSAASVLGNQGQGNYAAANAFLDGLAHYRRQQGLPAVSINWGPWDSVGIAVSDTAIA
DHMGRLGFTGIKPEVGIAALEKILAANIAQISVIDWDWQKYLAQLSTPRNFFGELSKTAP
SATMDGGATPEILHELQQASPEKRKQLLGALVHDTVRRTLGIHESVLLDPAKPLADQGLD
SLMAVQMRNVLGNNLRQALPVSLAFNYPTVNDIMDYIEVLMDKALGSIEPSAAAAQPAQH
DDSASSSAHALLADLDKLLDEQDLNA
>F8B5B8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Candidatus Frankia datiscae|TrEMBL
MTDVAIVGLSARFPGAASLGEFWRLIQEADPQFHEVPDSRWIHRTFYDPLNPRSPHRAYT
DRVAFVDDVDRFAAAHYRIPPRRARAMDPQQRLLVHLAREALQDAGLERRPFDRARTGVY
VGISQSDYRELAGARVRASLLANGSLHGGEADPDLLAAVERAADAGIAPLQAYTLTGCLL
NMAAGTISSVFDLGGPAFAIDSACSSVPVALHEAVLALRTGVCRVALVGGVFLNLTPDAL
ISFSRVGALSPSGVCRPFDERADGFVLGEGGGVAVLRPLADALADGDRVYAVIRGIGITN
DGRAAGPMTPSVHGQLAALRAAYADAGVAPGTVTVIEAHGTGTTVGDRTEIAALRDLRAG
DPTAEPCDLLSTKALIGHTLAAAGAASLVKMALALYHGVVPPQPETRPDPALPLAEAGLR
VPTRPRMWTDTEERPRRGAISSFGFGGTNVHVILDRARRRADGPARSDTPPRRPWLLLLS
ASSVELLASHAEAVRDTVEADPTITPAALSHTLATRELLPARLSLVAASRAQLCRQLTEA
AARLRAGRLGELPDGGYATSAPLPEADRRSALMFPGQGAQRPGMLADLYGRFAGFAARAD
ASDGVLRPLLGRSLADLVWDPHPDADQRAAEAAETAETALTATEICQPVLGALGIAVGEL
LTHCGLRPDVCVGHSVGELPAAVTAGAVDPADALRFLAERGAAVAGAQPAWHGGMLAVHT
GETTFHRLAAGIDGVWLGCVNHPSQLVASGRLDALERLCERAAAEGITTRQLRVSHAFHS
PLVAEADARMANTLAALPIQAPKTIIASSVSGHRCDDPRELRALWARHCSAPVRFMDAVR
DAAAAGARIFVQAFGGDSLLSMAHRSLAGSVQARYVALTASQPDDGRTLLAGLGQLACLG
VPLDILPLFGPGERELVTLPPSPLATSAYSIRINAAGSPAGPARPYSEPATAPARRGTGS
VAVPGQRGTGPDAPTADDQAVGDATASTGSAGAGSTGNEPVRMAPAATQRRVGGAGNLVA
AYRPAPDGERAAARPRRGEVPLSASRDANTIAYSPESHMDNVIRLLDKQLDLLRTLSGPA
AGAPRTSVSLSEAATPRQPAPDVPAAAGDTGALPQSLVPPGGHDPAASLVPTTVVVAPAR
GRDVLRAQVIEAISGLSAYPESHIHEDHAFVGDLGFDSIMMTDLVNALGRRWPGLTVRTE
DIAGITTVGDLVTVLARRAGSAGLLPETAGPPARGSSETAGSDQAGLGTGIGAGIGAGID
ARPRNSHGPAAQPHPRGTGNGLLDTAGNGAGHHRTDGSRAHPGPDSAATDVTSFPEVVAL
RERHELGGRLGLRSPYFLLHEGNVRDRTVVAGRELVSFSTYNYLGLSGHSEVNAAVSESV
DRYGSSVSAARILSGDRPPHRELEAELATLIGVEDCVVLVSGHATNVTTIGHLVGPDDLI
VHDALAHDSILQGARLSGATRRPFPHNDVAALDGLLAQVRHRFRRVLIVVEGVYSMDGDI
ADLPELIQVRNRHGALLMVDEAHSIGVIGAAGGGVGEHFDVDRGGVDVWMGTLSKSLASC
GGYVAGRRALVGYLRYTLPGFVYSAGLTPPNTAAALAALRVMRGEPARLARLRDNSALFL
RLAREAGLNTGTSAGTPIIPCIVGDSIRSVQLANTLFERGISVNPIMYPAVEERLSRLRF
FITSEHTPEQIAWTVETLAGELNTAVSSQLVDAG
>A0A1S8PPN5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Clostridium beijerinckii|TrEMBL
MEYKNDDYLTLIQASIKKINALKEKLDNKNNQEDIAIIGMGCRLPGGGSNPEEFWKFLVN
KGDGVIEVPKDRWNIDEFYSDNRNSFGKMYIKEAGFLQNNISEFDAHFFGISPREAVEMD
PQQRILLEVAWEALERSGIPMNNLKGSKTGVFVGVIGSEYSFLPRKDIQINPYVLTGSMA
NIVSGRLSYILGLQGPSISIDTACSSSLTAVHLACESLKNGGSDLALAGGVNLIISPQGF
VSLCSLNALAKDGRCKTFDASGDGYGRGEGCGVVVLKRLSDAVKDKDNILAVIKATGMNH
DGASSGLTVPNGFAQRDLILKTIKQANVSPEDISYFELHGTGTALGDPIEFKALTQVFKG
NRKDPLILGSVKNNIGHLEGAAGIASLIKSVLCIKEKTIPANLHLKNINPRIKLDSIPAI
LPTESLPWNNQGKKRIMAISSFGFSGTNVSLVLEESTEVSREYNSADTERPIHILALSAK
SKKALYDLAKKFYEYLKDETKERIQDICFTMNSGRMHFSCREAFKGENLGSIKTQLSEYI
SSNSKESLLEESMSNDENNKIAFIFSDKFDEEVGIELLKTQPNFKEELIKCDNKLKELVN
ISILGKDKFNHAVEGIEEIISFCVQCSILAMLNSFNIIPNVVVGNNKGCLIAAVASKVMD
IETALSYLIENSKFKIRKRIKRVLNKPRIRMIVGNNDEFILNSQATSDDFWNELLSKELN
SRGYIKNLVDKDYKNFIDFNLNDNSTGYSEIQYFNLALRGNVWNTLTDILSKFYCFGVDI
NWNEFDKGYIRNKLTLPTYQFQKKKFWCNTIPYGEYLYAENNVSKNLFDGEILKSPFKDK
QILYSLSLNKVPELTDTQNVVHVGYFIEFLKRAIKKIYNKEFYIKKFEFISALIISKDIT
TDLSLILSSKDDNEIEFCFYSSQGDDNWTNTSKGIVGFIQENEKVVFSDFEIDIKERCSE
KYSQDEFYDELEKRNMHLGESVKWIGDVWRRDNEALAMLISPKNSKGNTEHDIGININIL
DSCAQLFHAALPKQSDPLMRYMVSKWEDFKINNVNSINELWCHVTIEEIKKNELKGKFRL
YNQDGVLISEISSGLMKGLSKEHDEALKKILESKKQNSNLLQAESAIIKILKQTDKKEWI
EIIINYLLEIFASIFLMNKEEINIKESLIDLGLDSIVSIEVKGKIESELKIFLPIETLIE
GPSILELSEVIMPLLSIDNVIENAQEKEKIQNDNKNIGAWIMHRKANLNAKIKLFCFPYG
SGGGASIYRNWHNKLPDFIEICPIQLPGKENRIKEDAFRDINTAVDTIKEIILPELDRPY
AFYGHSMGALIAYKLAYDLKVKNNNGPNHLFVGAYSSPTIIPNPLILMTKERFRRAGYTD
IPKAEELKSMNSEEIEKIVDVITSKVDKSRELVRLYLSTRLSELEMVQSHKQVGKEKFDI
PITAFYGKSDDKVKYDEMIKWNDLTTEDFKINSLPGDHLFLKEDQSEDNLLELMGLELKK
YK
>A0A3N6FZA2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI96-15|TrEMBL
MDWETHYAGTRPRHVDLPTYAFQRQHYWPRFAELGGDVSSAGLDSPDHPLLGASVELAGG
DGLVATARWSLRTHPWLADHAVSGTVIVPGTALVESVIRAGDVLGCGRIEELALQAPVVL
QERGEAQVQIGVGEPDASGRRPVTVHTRTTGPDGATEDLWTLRAQGTLTEPGAPAVDRPE
EFTSWPPPGATAVAAEGFYELLAGRGYEFGPVFQGVRATWSRGEDLYAEVVLPEQVRGDA
GRFGIHPALLDAALHAAHLAPGSAGRTVVPFTWSGVCLHAAGATALRVRVSPAGQDAISV
QLTDPTGAPVATIDALAVREIAPDTLDPSARAARDWLFRLDWTPVTPPAAVPAATGWAVL
GTPADPVTAPDGSGTTLPAFATPGALAEHTEATGHRPGAVLLFAGAAASGTAAAPDAEPG
VPDAVLDDVLATVQSWLADETTEGVPLVVVTRGAVSTGPADPAHDLPGAAVWGLVRSAQS
QHPGRLVLVDLDIHDDSWLALPAALAAGEPQLALRQGAAYAPRLVRPRTSDALTVPEGTG
NWRLDIPEKGSVDRLDLVAAPGTAEEPAAGEVVIEVRAAGLNFRDVLNTLGMYPGPAVLL
GAEAAGVVTAVGEGVTGFAPGDRVMGLVSGGFAPRAVADARMLAPVPDGWTWAQAASVPV
AFLTAYYGLRDLAHLDSGESVLVHAAAGGVGMAAAQLARHWGAEVYGTAGDHKRTLLRAD
GWDDAHLASSRTLAFEDRFRATSGGRGVDVVLNSLAGDYIDASLRLLAPGGRLVDMGKTD
VRDPGQVLRDHPAAALYQAYELREAGEDRIQEMFRDLSELFASGALRPLPTVTWDVRHAR
EAFRHMAQAKHYGKIVLTLPRAWDPEGTVLVTGGAGVLGGILARHLVTRHGMRHLVLTGR
RGPDTPGAGELAAELRELGAEVTLAACDAADADALAAVLAAVPAEHPLTAVVHAAGVLDD
GVLESLTPDRLRTVLAPKADAARHLHRLTRDLDLADLVLFSAGAGVFGNAGQANYAAANT
YLDALAHRRRADGLPTTSLSWGLWADTSALTGQLDDTDLARVRRSGVLPLSAADGMVLFD
AALAEQRPHLVPVRLETGQLRASGDEVPPLLRSLYRGPVRRTAEAGAAAGTDGLRARLAG
RSAEDRLSTLRDLVGAHAAAVLGHDDTEPFHAGRAFRDLGFDSLTAVELRNRLSAATGLR
LPATLVFDHPTVAALAAHLDGELSDGTPAALPAAPAPAPAAPGDDDPFAIVGMACRLPGD
IHSPEDLWRLLADGADAVAPFPDDRGWDLARLYDSVPEGQGSSRTREGGFLHDAADFDAD
FFGISPREALAMDPQQRLLLETAWETFERAGIDPRSVRGSRTGVFAGLSSSDYLKRVTHV
PDEIAGYVNNGNANSIVSGRVSYTLGLEGPAVTVDTACSSSLVALHMALQALRRGECTMA
LAGGVTVMSSPEIIVDFSRQRGLAADGRCKPFAEAADGTGFSEGVGLILVERLSDARRNG
HQVLAVVRGSAVNQDGASNGLSAPNGPAQQRVIRQALADAGVGAAEVDAVEAHGTGTRLG
DPIEAQALLATYGRDRDGGHPLFLGSVKSNLGHTQAAAGVAGVMKMVLALRHRLLPESLH
IDAPTPHVDWADSGVRLLTEATAWPEPSASRPRRAAVSSFGISGTNAHVILEEAPAVPGP
DGGEPEPTGADATETRPMPLPWVLSARSEAALRGQAKALLTHLDAHPGTDPADIAHTLVT
RRAQLEKRAVVVGSATGDFRAGLAALAEGSPAAHVVTGGRGAGRDRRTVLVFPGQGSQWA
GMGAELLDASPAFAGRVAACEEALAPYVDWSLTAVLRQEEGAPALDRVDVVQPVTWAVMV
ALAEVWRAHGLRPAAVLGHSQGEIAAAAVAGALSLADAARIVAVRSRAIARELSGHGGMV
AVTAPHDEVTALLADLPGVCVAAVNGPSSVVVSGDTGGLDTLLAACEEQGVRARRVPVDY
ASHSAHVDRLAESLPAALDGIEPRDGDIPFFSTVTADWHPGTGLGAAYWHRNLRGTVRLE
ESLRALVEQGHDVFVECGPHPVLTVGIEDTVAALGADAVALGSLRRDDGGPARVLTALAA
AHVEGVHVDWRPAVSHGTAVDLPTYAFQRRRYWLDAGTPQGDPAGLDSVVRLADGGAVLS
GSLSLATQPWLDAHRTHGAAVVPTTALLDWAVRAGDETGLPVVAALDEHSPLVVPEEGRV
EIQLSVSAADTDSRPFSVHSRLHAADAGEPAAPWTRNATGDLTDRPTTTPQASGTWPPAD
AVAGDPAPVRALAEDRGLDLAAPFDTVRSLWRAGTDVLAEVALPDTAHADAARFRLHPAL
LQTPLALAATTEEATAPVLPAAWRDVTVHATGATRLRVRLTPGDDATWSVEARDAAGDLV
LTGTAVTRPAGPDRFPATAGPDAPHRVAWLPWTDTTSSATPEPHGPWAVIGAPGRLTAAL
ERSGATVQLHPDLAALTTALDNGEAAPPALVVAFHGHDSGEDPTRAAHTSAARALELSTA
WLREPRLADARLLLVTEGAVATGPDDTVPGLADATAWGLLRSAQTEHPGRFLLADLDPAP
GDTDEDSAADTLIAAAAAAARTGEHQFAVRAGTVTVPRLVPAGHPEGAPAPAATAPWGEG
TGAGTVLITGGTGTLGALVARHLVTRHGVRHLLLTSRRGPGAPGAAALREELAALGAEAE
IVACDVADREQLAGALDAVPAEHPLTAVVHTAGVLDDGTLDGLTPDRIAHVLRPKADAAW
HLHELTRDTKLTAFVMFSSYAGVAGGPGQANYAAANAFLDALAQHRRASGLPAHSLAWGL
WEDRSDLTGALDTTGLARLERSGIRPLTAGQGLALLDASTALDTAHLVPVRLDTRTLRAD
EVPPLLRALARPAVRRAADSGPGAATGAPADLRERLAGLSGPQQRALLHRTVLGHLAAVL
GHASAASLDADRGFLDLGMSSLTAVELRNRLNADTGLSLPTTLIFDHPDPAALVRHLQTE
LGTATGEPDQAVFAELAALEAAVGGAALDDQDRARLAQRLKALGWKLDATSQGADEPDDD
SDLDTTTDDEMFDLIDNELGLA
>A0A3G4VPL9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-16|TrEMBL
MLNDSQDFAAETDDASEAGGTQGTEREPHGTDSGGAAGDGGGETSGDAGSETGAETGADA
ASGGTDGPDGWRERLAGLTETEQHTTLLDWVSSLVTASLRDAAPTALDPQRSFLDLGFDS
LAAVDLHARLVAGTGLRLPVTLAFDHPTPAHLARRIHALLLGLTAPAEAPVTAAISSDEP
IAIVGIGCRFPGDVHSPEALWELVANGTDAISEFPTGRGWNLDSLYDPDPDRAGTTYARE
GGFLHDADEFDAAFFGISPREALAMDPQQRLLLETSWEAFDRAGIDPSGLRGGQVGVFVG
AETQEYGPRLEDAADGFEGYLVTGNAASVASGRIAYTFGFEGPTVTVDTACSSSLAALHL
AVQALRSGECSLALAGGVAIMASPGSFVSFSRQRGLAPDGRCKPFAAGADGTAWGEGAGM
LLVERLSDARAAGHHVLAVVRGTAINQDGASNGLTAPSGPAQQRVIRQALANAGLTSADV
DAVEAHGTGTTLGDPIEAQALLATYGQDRPAERPLRLGSLKSNIGHTQAAAGVAAVIKMV
MAMRHGMLPQTLHVDAPTPHVDWEAGAVSLLTEPVAWPTADAPRRAGVSSFGMSGTNAHA
IIEEPPTEDAAQHTADQPPAQEAPGTDEPEAAAGQLPLLPWALSAKTPEALRATARRLGD
WLDTHPDATPLDIGHSLATTRSRFEHRAVVLGDDRASLQRGLHALADAADTPAVIHGEPA
AGRPAVLFTGQGSQRLAMGRELYETYPVFADALDDASWYLDEQLEHPLLDVLFADEDTPE
AALLHQTAYTQPALFAVEVALYRLVESWGLRPAFVAGHSVGEIAAAHVAGVFTLEDACAL
VAARGRLMQALPTGGVMIAVQASEDEVLPLLTDRVSIAAINGPQSVVVAGDEDAALAVAE
AFEAQGRKTKRLTVSHAFHSPHMDAMLDAFRRVAQVLDYGTPTLPVVSLLTGTTATAAEL
ATPEHWVRHVREAVRFLDGVRTLRARGADSFLELGPDPVLTAMAQDCLVTDPQDTTNPVF
AAALRSGRPETTTLLDAVARMFVRGAETDWAACFAGTGARSVELPTYAFQRQRYWMNART
PAIEPAASPAHRTDPADNAFWDAVEHQDVAALAAALELDADGEQPLSEVVPALSAWRRRV
RTQSEVDGWRYRVSWKPLTDAAAGGVRLSGSWLVVVPSEGVDDAPVVGALAGRGAEVRRV
VVEAGADRAGLFSDVGSVAGVVSLLALDEAAGVVATAGLVQALGAAGVEAPLWCLTRGAV
SVGRSDRLVSAVQAQTWGLGRVVALELPERWGGLVDLPEVWDERAMARLVGVLAGSGEDQ
VAVRSSGVFGRRLVRAADGGAESWTPSGTVLITGGTGALGGRVARWLAGAGVERLVLTSR
RGIDAPGAAELLELGVDVSVVACDVADRDALRTLLAAEAEGLTAVVHTAGVLDDGVLDAL
TPERFESVLRAKATSALNLHELTVELGIELSAFVLFSSMSGSIGAAGQGNYAAANAYLDA
LAEQRRAAGLAATSIAWGPWAEGGMAADEAMDARMRREGVPPMAPDSAIAALAQAVGAGE
AALTVADITWDRFSSVVAAVRPNPSVADFATATSQGAASVTGQGTVVTGTDVAGAAFAKL
AELPRAEQDRELLGLVRTHVAAVLGHDGADAVGAERAFKELGFDSLTAVDLRNRLGAATA
LRLPATLVYDYPTSSALAEYLRGELMGNAPKADSPQHVAAATDDDPIAIVAMSCRFPGGV
RTPEDLWRLLAQGTDAVADFPADRGWDLDRLYDANPEQPGTSYTREGGFLYDAAEFDAGF
FGISPREALAMDPQQRLLLETSWEAFERAGIDPALLKGSQAGVFVGTNGQDYLTLVAGEA
DGLEGHVGTGNAASVVSGRLSYVFGLEGPAITVDTACSSSLVALHLAVQALRQGECSMAL
AGGVTVMSTPDAFIDFSRQRGLAEDGRIKAFAAGADGTGWGEGVGMLLVERLSDAQRNGH
PVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRQALASAGLSAAEVDAVEAHGTGTRLGD
PIEAQALLATYGQERPEGLPLLLGSVKSNIGHTQAAAGVAGIIKMVLAMQYGVLPRTLHV
DAPTPHVDWSAGEVELLTEQRNWPETGRPRRAGISSFGLSGTNAHTIIEQAPDADADEAP
AAPAEGTATAALPFAVTGKNPAGLRAQAQQLVSWLAENPQAAPADIAYSLAAGRSTFETR
AVVVADAADRDALTAGLRALAAGEHATGLVRGTASGGGLAFLFTGQGSQRLGMGRELYDT
YPVFADALDAVCARMDAHLELPLTEVLFGPDAAVLDRTEYTQPALFAVEVALFRLAESWG
VKPDFVSGHSIGEIAAAHVAGVFSLEDACALVAARGRLMQALPEGGVMIAVQASEDEVLP
LLTDRVSIAAVNGPRSVVVAGDEDAALAVAAAFPDRKSKRLTVSHAFHSPHMDGMLDDFR
RVVEGLSFGAPRIPVVSNLTGALVADEMGSAEFWVRHVREAVRFLDGVRVLEGAGVTSFV
ELGPDGVLSALAQDCLTGDADVAFVPVLRAGRGEAETLVTAVAQAHVRGVEVDWSAFFAG
SGAGRVELPTYAFQRQRFWPETILSNGAVVAAPTVDAVDARFWDAVERGDLASLVAELSV
SDDASFGELVPALSAWRRQNQEQAQVDGWRYRVSWKPLAGPAASAGVLGGEWVAVVPSAR
EDDALVAGVLGALTGRGAEVRRVVVEPGADRVALAEQLSGFGSVSGVVSLLALDEAAGVV
ATASLVQALGDAGVVAPLWCLTRGAVSVGRSDRLVSAVQAQVWGLGRVAALELPERWGGL
VDLPEVWDERAMARLVGVLAGSGEDQVAVRSSGVFGRRLVRAADGGAESWTPSGTVLITG
GTGALGGRVARWLAGAGVERLVLTSRRGADAPGAAELLELGVDVSVVACDAADRDALRAL
LAAEAETLTAVVHTAGVLDDGVLDALTPERFESVLRAKATSALNLHELTGELGIELSAFV
LFSSMSGTIGAAGQGNYAAANAYLDALAEQRRAAGLAATSIAWGPWAEGGMAADEALEAR
MRRDGVPPMDAQPAMRALRQAVGAADASLTVADVEWERYLSGHTAVRRSELFSELTEVRA
TRAGTDARTQTAEHTGGAVTLAGRLAALAPAEQTRELLGLVRTHVAAVLGHDGADAVGAE
RAFKELGFDSLTAVELRNRLGAATELRLPVTLIYDYPTSAALAEHLREELVGSIPVSGAL
LPVAAAVDGDPIAIVAMSCRFPGGIASPEDLWQLLAQGTDAVADFPADRGWNLDRLYSPD
PDQPGTSYTRQGGFVAGAAEFDADFFGISPREALAMDPQQRLLLETSWEAFERAGIDPSS
LRGSRAGVFVGTNGQDYLSLVAREQDGLEGHVGTGNAGSVMSGRVSYVFGLEGPAVTVDT
ACSSSLVALHWAIQALRQGECSLALAGGVTVMSTPENFIDFSRQRGLAEDGRIKAFAAGA
DGTGWGEGVGMLLVERLSDAQRNGHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRQA
LASAGLSAAEVDAVEAHGTGTRLGDPIEAQALLATYGQERPEGLPLLLGSVKSNIGHTQA
AAGVAGIIKMVMAMRHGVLPQTLHVDAPTPHVDWSAGEVELLTEQREWPETGRPRRAGIS
SFGISGTNAHTIIEQAPDTEQSAPADAQPAVRPARVLPYLLSGKTKEAVRAQAASLTAHL
DAAEGADGGVDAVDLAYSLATSRAHLDQRAALVLTVADGQDLRETLARLAAGESVAGITT
GTAGDARTAFLFTGQGSQRLGMGRELYDAHPVFADALDAVCAQLDAVLDRPLKDVLFGSD
ASLLDETRYTQPALFAVEVALFRLVESWGVRADFLSGHSIGEIAAAHVAGVFSLDDACAL
VAARGRLMQALPAGGVMIAVQASEEEVLPLLTDRVSIAAVNGPRSVVVAGDEDAAVAVAD
AFPDRKSKRLTVSHAFHSPHMDGMLEDFRQVVEGLSFEAPHTPVVSNLTGALVTDEMASA
EFWVRHVREAVRFLDGVRALEAAGVTAYVELGPDGVLSALAQDCLTDTTHTTFAPALRAG
RPEAETLVTALARAHVHGVEVDWAAYFAGSGARRVDLPTYAFQRQRFWPSAALFAAGDPE
AIGFGDAGHPLLSAAVALADSEGVLLAGRLSVETHPWLVDHTILGSALLPGTAFVELAIR
AGDEVGCDVVEELTLEAPLVLPERGGVQLQLVVEAPTEPGRRPFSVYSRRRDALAEESWT
RHGSGVLAAGARPEASLAFADLAAWPPAGAVPVDIDGLYTDLAQAGVSYGPLFQGLKAAW
RRDGELFTEVVLPEDGRGDAARFGLHPALLDAGLHAIGHGDPAEQAATGALLPFSWAGVS
LYAAGASSLRMRLTPNSAGDPHTLALLVADETGRPVAAVESLTLRPASADQVSAAGAGHL
ESLFRVEWVPAPVATAPAGLRWGVLGRDEIGLAGSTGAQVTEYADAAALGAALVAGEPAF
DAVFVVPSAPVRGADVIGSVHTAVNDALAVVQEWLADERFATTRLVWLTSGAVAVGSGEG
VRDLAGGAVRGLLRSAQSENPGQLLMLDVDEASLAAVPAALAAGEFELAIRSGVVCVPRL
VRVPSSESIADSPVVLGDPSGTVLVTGATGSLGRLFARHLVTAYGAERLLLVSRRGPAAD
GADELIAELARLGAHADLVACDIADRGELAALLASVPVEHPLTAVVHTAGVLDDGVLSSL
TPERVASVLRPKVDAAWNLHELTRDLDLSAFVLFSGAAAAFGAAGQANYAAANAFLEALA
EQRRAEGLPAASLAWGLWAPQAGSSGEGMASRLDEVDLRRIARDGVGALGAEEGLGLFDT
AMTVDSAVLMPIRLDLAVLRAQAVSAGSTPALLKGLVRVPARRTLERRTGGGADAGSPLV
ARLLALPVAEHEGVLLDLVCGRVAAVLGHTGADAVDAERAFRDLGFDSLTAVELRNVLKA
ETGLRLSPTLIFDYPTPVALARHLLAELAVTGGLGARDGVRVPVRAAVDVTDDPIVIVGM
GCRYPGGVRSPEELWQLVATGGDGVTAFPSDRGWNVEALYHPDPDHAGTSYTREGGFLHD
VADFDPAFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATLRGSRTGVFAGVMYHDY
VTGFGLGDGAGSGDALPEGVEGYLGTGNAGSIASGRIAYTFGLEGPAVTVDTACSSSLVA
LHWAIQALRGGECDMALAGGVAVMATPETFVDFSRQRGLSADGRCKSFAAAADGTGWAEG
AGMLLVERQSDALRNGHPILAVVRGSAVNQDGASNGLTAPNGPSQQRVIREALASAGLSA
VDVDAVEAHGTGTRLGDPIEAQALLATYGQDRPEGRPLLLGSIKSNIGHTQAAAGVAGII
KMVMAMRHGVLPQTLHVDAPSTQVEWEAGDVSLLTQAMDWPQTGRPRRAGISSFGISGTN
AHTIIEQPPVLERAEPESAALLPAVPWVLSAKGEDALRAQARQLHSHVTSTPGARPVDVA
WSLAANRASFEDRAAVVAADREGLLAGLAALAEGRSTATLVEGSPVAGKLAFLFTGQGSQ
RLGMGRELYDAYPVFAAALDAVCEQLNLELPLKEALFGGDREVLDRTEFTQPALFAVEVA
LFRLMESWGVRADFLSGHSVGEIAAAHVAGVFSLEDACTLVAARGRLMQALPSGGVMIAV
QASEDEVLPLLTDRVSIAAINGPRSVVVAGDEDAALAVAEAFPDRKSKRLTVSHAFHSPH
MDGMLEDFREVVAGLSFGAPRIPVVSNLTGALVTDEMGSAEFWVRHVREAVRFLDGVRAL
EAAGVTSFVELGPEGVLSALAQDCLAGAADVAFVPVLRAGRGEAETLVTAVAQAHARGVE
VDWSAFFAGTGARSVELPTYAFQRQRYWLQLTGAVRSGAGYDVDSRFWDAVEREDVASLV
GTLAMDDENGWSAVLPALSAWRRGLRTQSEVDRWRYRVSWKPLTDAAAAGVRLSGSWLVV
VPSEGVDDAPVVAALAGRGAEVRRVVVEAGADHAGLFSDLGSVAGVVSLLALDEAAGVAV
TAGLVQALGAAGVEAPLWCLTRGAVSVGRSDRLVSAVQAQTWGLGRVAALELPERWGGLV
DLPEVWDERAMARLVGVLAGSGEDQVAVRSSGVFGRRLVRSTAGNAESWTPSGTVLVTGG
TGALGGRVARWLAGAGAERLVLTSRRGMDAPGAAELVADLSGLGVDVSVVACDAADRDAL
RTVLAAEAEGLTAVVHTAGVLDDGVLDALTPERFEGVLRAKATSALNLHELTAELGIELS
AFVLFSSMSGVTGAAGQGNYAAANAYLDALAEQRRAAGLAATSIAWGPWAEGGMAADEAM
DARMRREGLPPMAPDTAMAVLRQSVVPSADAALLVADVDWERFGPAFTVARPSTLFAELS
ETRPAAEGAATGTGSSVDRFAGLAAVELERELLGLVRTHVAAVLGHEGAETVGAERAFKE
LGFDSLTAVELRNRLGAATGVSLPATLIFDYPTASAITAFLRDELLGTQARIAGPVSTTV
TAVDDDPIAIVAMSCRFPGGVRTPEDLWQLLATGGDAIGEFPVDRGWDLDRLYSPDPDQQ
GTFYAREGGFLYDAADFDADFFGISPREALAMDPQQRLLLETTWETFERAGIDPAAVRGS
QAGVFIGTNGQDYDATFHSVPDGIEGFLGTGNAASVVSGRLSYAFGLEGPAVTVDTACSA
SLVALHWAIQALRNGECDMALAGGVTVMSSPGAYIDFSRQRGLAEDGRIKAFSADADGTG
WGEGVGMLLVERLSGAQRNGHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRAALASA
GLSAAEVDAVEAHGTGTRLGDPIEAQALLATYGQERAEEQPLLLGSIKSNIGHTQAAAGV
AGVIKMVLAMQHGVLPQTLHVNEPTPHVDWTAGEVELLTEQRDWPETGRPRRAGISSFGF
SGTNAHTIIEQAPDVLDVEPPVQPQERPGGVLPWVLSAKNEAALRVQAERLLAAVTSDEL
LEPADMAYSLATSRSALERRAVVVAGERDEFLAALRALAAGEQTAGVTHGTAAVGGTAFL
FTGQGSQRLGMGRELYDAHPVFADALDAICARMDAHLELPLADVLFGSDAAVLDRTEYTQ
PALFAVEVALFRLVESWGVRADFLSGHSIGEIAAAHVAGVFSLDDACALVAARGRLMQAL
PAGGVMIAVEASEDEVLPLLTDRVSIAAVNGPRSVVIAGDEDAAVALAESFADRKSKRLT
VSHAFHSPHMDGMLDEFRQVVAGLSFEAPRIQIVSNLTGSVVSDEMASAEFWVRHVRDAV
RFLDGIRVLEAAGVTAYVELGPDGVLSALAQGCLADENSDALFMPVLRKGRPEVETLVTT
LGQAHAHGAEVDWAAYFAGSGARRVDLPTYAFQRQRFWPSAALFAAGDPEAIGFGDAGHP
LLSAAVALADSEGVLLAGRLSLDTHPWLADHMILGSALLPGTAFVELAIRAGDEVGCDVV
EELTLEAPLVLPERGGVQLQLVVEAPMAPGRRPFSVYSRRQDALAEEPWTRHGSGVLAAG
AQPEASQEFGELAAWPPAGAAPVDIDGLYAELAGDGMAYGPLFQGLKAAWRRDGELFTEV
VLPEDGRGDAARFGLHPALLDAGLHAIGHGDPAEQGASGALLPFSWAGVSLYAVGASALR
MRLTPNSAGDPHTLALLVADETGRPVAAVESLMLRPASSDQVSAAGAGHLESLFRVEWLP
APVATVSAPAGLRWGVLGRDEIGLGSSTGAEVTEYADVTALGAALAAGEPAPDAVFVLPT
ASASTADTIGSVHTAVNDALAVVQEWLADERFATTRLVWLTSGAVAVGSGEGVRDLAGSA
VRGLLRSAQSENPGQLLMLDVDEASLAAVPAALAAGEFELAIRSGVVCVPRLVRVPSSES
IADSPVVLGDPSGTVLVTGATGGLGRLFARHLVTAYGAERLLLVSRRGPAADGADELIAE
LARLGARAELVACDIADREALGELLASVPAEHPLTAVIHTAGVLDDGVLSSLTPDRVASV
LRPKVDAAWNLHELTQGLDLSAFVLFSGAAAAFGAAGQANYAAANAFLEALAEQRRAEGL
AAVSLAWGLWAPQAGSSGEGMASRLDEADLRRIARDGVGALGADEGLGLFDTAMTVDSAV
LMPIRLDLAVLRAQAVSAGATPALLRALVRVPARRTATRRDGGAESGSPLTARLLALPVA
EHEGVLLDLVCGRVAAVLGHTGADAVDAERAFRDLGFDSLTAVELRNVLKAETGLRLPPT
LIFDYPTPAALARHLLSELAVTGGSGDQDGSRGVLTPVRAAVDVTDDPIVIVGMGCRYPG
GVRTPEELWQLVASGGDGVTAFPTDRGWNVEALYHPDPDHVGTSYTREGGFLHDVAEFDA
AFFGISPREALAMDPQQRLLLETSWEAFERAGIDPATLRGSRTGVFAGVMYHDYATGYGN
GEELPEGVEGYLGTGNSGSIASGRVSYAFGLEGPAVTVDTACSSSLVALHWAIQALRGGE
CDMALAGGVAVMATPETFVDFSRQRGLSADGRCKSFAAAADGTGWAEGAGMLLVERQSDA
LRNGHPILAVVRGSAINQDGASNGLTAPNGPSQQRVIRQALASAGLSTAEVDAVEAHGTG
TRLGDPIEAQALLATYGQDRPEGLPLLLGSIKSNIGHTQAAAGVAGIIKMIMAMRHGVLP
QTLHVDTPSTQVEWEAGDVSLLTEAMDWPQTGRPRRAGISSFGISGTNAHTIIEQPPVLE
RAEPESAAQLPVVPWVLSAKGEDALRAQARELQAHLLAAPDVRPVDVAWSLAANRASFED
RAAVVAADREGLLAGLAALAEGRSTATLVEGSPVAGKLAFLFTGQGSQRLGMGRELYDAY
PVFAAALDAVCEQLNLELPLKDVLFGTNAALLDETRYTQPALFAVEVALFRLMESWGVRP
DFLSGHSIGEIAAAHVAGVFSLEDACTLVAARGRLMQALPSGGVMIAVQASEDEVLPLLT
DRVSIAAVNGPRSVVIAGDEDAAVALAESFADRKSKRLTVSHAFHSPHMDGMLEDFRQVV
EGLSFGAPRIQIVSNLTGALVTDEMGSAEFWVRHVRDAVRFLDGVRALEDAGVTTYLELG
PGGVLSAMGQECLTGEGAAFVPVMRNGRPETEAMVAAAAQAHVRGLKVNWHEFFVGSDAR
SVELPTYAFQRQRYWLQMAGVTRSGVADELDSRFWDAVEREDMESLAATLDMDDENAWDT
VLPALPALSAWRRGLRTQSEVDRWRYRVSWKPLTDAAASGVRLSGSWLVVVPSEGVDDTT
VVDALAGRGAEVRRVVVEAGADRVGLFSDVGSVAGVVSLLALDEAAGVVSTASLVQALGA
AGVEAPLWCLTRGAVSVGRSDRLVSAVQAQTWGLGRVAALELPERWGGLIDLPEVWDERA
MARLVGVLAGSGEDQVAVRSSGVFGRRVVRAVGGDTGSWTPSGTVLVTGGTGALGGRVAR
WLAASGAERLVLTSRRGADAPGAAELTGELSGLGVDVSVVACDAADRDALRTLLAAEAET
LTAVVHTAGVLDDGVLDALTPERFESVLRAKATSALNLHELTAELGIELSAFVLFSSMSG
VTGAAGQGNYAAANAYLDALAEQRRAAGLAATSLAWGPWAEGGMAADEAMDARMRREGLP
PMAPDTAMAVLRRSVASSSDAALLVADVDWERFGPAFTVVRPSSLFAELAELAEVRPAGP
VARTAGGTGSSVDRFAGLGAVELERELLGLVRTHVAAVLGHEGAETVGAERAFKELGFDS
LTAVELRNRLGAATGVSLPATLIFDYPTAAAITAFLRDELLGSEVQMTAPTVTAVADDPI
AIVAMSCRFPGGVRTPEDLWQLLAAGGDAIGEFPVDRGWDLDRLYSPDPDRQGTFYAREG
GFLYDAAEFDADFFGISPREALAMDPQQRLLLETSWEAFERAGIAPSSVRGSQAGVFIGT
NGQDYGATLQALPDGIEGFLGTGNAASVVSGRLSYAFGLEGPAVTVDTACSASLVALHWA
IQALRNGECDMALAGGVTVMSSPGAYIDFSRQRGLAEDGRIKAFSADADGTGWGEGVGML
LVERLSDAQRNGHPVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRAALASAGLSAAEVD
AVEAHGTGTRLGDPIEAQALLATYGQERPADQPLLLGSIKSNIGHTQAAAGVAGVMKMVL
AMQHGVLPQTLHVNEATPHVDWSTGEVALLTERQAWPETGRPRRAGISSFGFSGTNAHTI
IEQAPDVLDVEPPVAPQQRPGAVPWVLSGKSEAALRAQAERLLATVTSNELLEPADVAYS
LATSRSALERRAVVVAGERDEFLAALRALVAGEQAAGVAHGTVSAGASAFLFTGQGSQRP
GMGRELYDTYPVFADALDAICARMDAHLELPLKEALFGSDGALLDETRFTQPALFAIEVA
LFRLLESWGVRPDFLSGHSIGEIAAAHVAGVFSLEDACALVAARGRLMQALPSGGVMVAV
QASEEEVLPLLTDRVSIAAVNGPEAVVVAGDEDAAVAVAAAFPDRKSKRLTVSHAFHSPH
MDGMLADFRKVAESLSYGSPRVPVVSNLTGALVTDEMGSADFWVRHVREAVRFLDGIRAL
EAAGVTTFVELGPDGVLSALAQDCTEQDALFVPVLRKGRPEAEAVVTALARAHVHGVTVD
WTAFYSGTAARRVDLPTYAFQRKRYWLEEAPRPSAVESGAGSAAVVDAPFWEAVDNADLD
ALAATLEIDADQPLSAVLPALSAWRRRRADRSVVDGWRYGVTWKPLGEPDGSRPSGTWLV
VTATTAETAGSGLPEIADALRARGVDVREVALDAAATDRAVVAERLGAALAGNRADGVLS
LLALAEAPHPAHPAAPAGLLLTGALVQALGDAGVDAPLWCVTTGAVATGPSDRVRSAAQA
QIWGFGRVVALEHPERWGGLVDLPAGVDARALDRLLAVLAGGRAAATAGSGTETGTAYED
QVAVRSAGLLARRIGHAAPAAGAGGDAGADRAPWRARGTVLVTGGTGALGAHVARWLAAQ
GAEHLVLAGRRGPRAPGIEALVAELAALGARATAVACDVTDRRSVGELLAALREDTSGPG
LTAVFHTAGVGQFAPLAETGPDEVAAVLAAKVAGAEHLDALLGDTELDAFVLFSSIAGVW
GSGGQGAYAAANAHLDALAQRRRARGLTATAVAWGPWGEGGLVADEEAAGQLRRRGLPVM
APELSITALQQALDADDTTVTVADVDWALFAPAFTAARPRPLIADLPEVRRALAAEQPGA
GGSGSAAGDDTAGEAARLAGELRGMGADEAERTLLGLVRTHVAAVLGHDGAATVEAGRAF
KELGFDSLTAVELRTRLGSATGLRLPASLVFDHPTPAALAAHIRAELLGEDTAPEVPALA
EIDRLEFLLTSVAEGDDAAERGRVTARLEALLAHWNRTERAAHPLEDEESAIESASAEDL
FDIINNEFGKF
>A0A2K8P9X7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces lavendulae subsp. lavendulae|TrEMBL
MANEETLRDYLKLVTADLHQTRQRLRDVEAKNQDPVAIVGMGCRYPGGATSPEELWQLVA
DGVDAITGFPAERGWDMDTVYHPDPEHPGTSYANQGGFVRDIARFDPSLFGISPREALAM
DPQQRLLLETSWEAFERAGIDPTSMRGKQVGVFVGTSNHDYLTALLSSSENVEGYLGTGN
AASVASGRLSYTFGLEGPAVTVDTACSSSLVALHLAVQALRNGECSMALAGGATLMAAPG
TFIDYSKQRGLATDGRCKAFSPDADGFSLAEGVGVLLVERLSDARRKGHHVLAVIRGTAV
NQDGASNGLTAPNGPSQQRVILQALSNARLTPDQVDAVEAHGTGTGLGDPIEAQAIIATY
GQDRPDGRPLWLGSLKTNIGHAQAAAGVAGVIKSVMAMRHGVLARSLHLTEPTPHVDWSA
GEVSLLTEARPWPQHEGPRRIGVSSFGMSGTNAHVILESGEETAQESGGEPAAGTPGSAV
EAAAPAAVLPVVLSGKTGAALRAQAATLHAHLTDRPGLRVADVAYAQALTRAALDRRAAV
VAENREELLAGLAALAEGRTGPEVLEGAATEGKLAFLFTGQGSQRLGMGRELYDAYPVFA
TVLDEVCARFELRLKDTLFGSDAALLDRTEYTQPALFAVEVALFRLLESWGLKPDFVSGH
SIGEIAAAHVAGVLSLDDACTLVAARARLMQELPAGGVMIAVQASEDEVLPLLTDRVSIA
AVNGPASVVIAGDEDAATAIVEAFPDRKSKRLTVSHAFHSPHMDGMLADFRRVAEGLTYE
SPRIPVVSNLTGALVTDEMGSAEFWVRHVREAVRFLDGIRWLESRGVTAYVEIGPGGVLS
ALGQDCQTATGARAAVFLPALRPGRPEARSLAAAVAGAHVHGLSPDWAARFAGTGARRVD
LPTYAFQREPYWPRDPFSDLTEPADGRALGATDAKFWEVVDSEDLAAFADTLGIDGDAPL
SGVLPALSAWHRRHRDRDTVDAWRYRVTWKPLTDAEPAPLSGHWLLVVPAGHTDDPWAVA
AARALTARGVTVSSLTVDATADDRAALAQRIGETLADADAPAGVLSLLALDERPHPEDPA
LPAGLAATLAFVQALGDADVDAVLWAATRGAVSTGRSDRLTALAQAPVWGLGRTAALELP
GRWGGLVDLPPNPDERAAARLADVLGGLGAEDHLAVRPTGVFARRLSRAPREEAPADAWT
ASGTALITGATGALGRHVARWLARTGAAHLLLVSRSGPAAEGAQELAAELRELGTRVTLA
ACDAADRDAVAALLAGVPADLPLTTVVHAAGVLDDGVLDAQTPRRMAEVLRPKAHAAQVL
HELTRELDLSAFVLFSSLAASFGAAGQANYAAANASLEALAEQRRADGLPATVIAWGAWA
EGGMATDELVAERLRSAGLPALAPELALSALHTALTLDETASVVADIDWERLAPGLTAVR
PCPLIADLPEAVHALTAAGAPDAAGAGAGTADNFATQLALAAPAERDTLALEFVRTQIAV
VLGYSGPAAVDPAIAFRDLGFDSLTAVEIRNLLTSRTGLRLPATLIFDYPNSLSLAAFLQ
GELLGDAPAGQGAAAGPVATVVDDDPIAIVAMSCRFPGGVRTPEQLWELLAAGRDAVSGF
PTDRGWDLEGLYDPESVTENTTYVREGGFLADATEFDPGFFGISPREALAMDPQQRLLLE
TSWEAFERAGIDPATVRGERIGVFTGTNGQDYLDVILAAPDGSEGFLGTGNAASVVSGRV
SYVLGLEGPAVTVDTACSSSLVALHWAIQALRAGECTMALAGGVTVMSTPASFIDFSRQR
GLAADGRIKAFAAGADGTGWGEGLGMLLVERLSDARRNGHPVLALVRGSAVNQDGASNGL
TAPNGPSQQRVIRQALASAGLSAAEVDAVEAHGTGTRLGDPIEAQALLATYGQGRSDGQP
LLLGSIKSNFGHTQAAAGVAGVMKMVLAMRHGVLPRTLHVDEPSPHVDWTAGDVALLTEP
VEWPETGRPRRAGVSSFGISGTNAHTIIEQAPEDEPAARTARTRPPTATVADVHAPADSA
SPLPWVLSGKTEGALRDQARSLLAHAERHPEARPADLALSLAVGRAAFEHRAAVVAADRE
ALLSGLEKLAEGAPAAAVVEGSPAGGKTAFLFTGQGSQRLGTGRALYEAQPVFADALDAL
CAHLDPHLELPLREVLFGSDAELLDRTGYTQPALFAVEVALFRLVESWGVKPDFLAGHSI
GEIAAAHVAGVLSLEDACALVAARGRLMQALPSGGVMIAVQASEDEVLPLLTDRVSIAAV
NGPTSVVIAGDEDAATAILAAFPDRKSKRLTVSHAFHSPHMDGMLADFRRVAEGLTYESP
RIPVVSNLTGALVSDEMGSADFWVRHVREAVRFLDGIRTLEAAGVTTYLELGPDGVLSAL
AQDCVTEDAVFVPLLRAGRPEAEAVTNALARVHVHGGTVDWAAYFAGTGARRVDLPTYPF
QRQRYWPAISGLYLGDVEAIGLDDTGHPLLSAGVALPESDGMVFAGRLALSTHPWLADHA
ILGSVLLPGTAFVELATRAGDQLGCDHLEELTLEAPLVLPERGGVQLRVWAGAADASGRR
PFALHSRPEGAPAEEPWTRHAAGVLAEAGRTAADFDLSAWPPAGATEVPLDGRYEALDAI
GFAYGPTFRGLRTAWQQGDAVYAEVALPEGTEDQAGRFGLHPALLDAALHAIGLGGVGAD
DGRGRLPFAWSGVSLYAGGASALRVRLTPAGAEGVRLEIADATGAPVAAVASLGLRPVTA
DQLRAARATYHESVFRRQWTELTGLTAPDGVRYAVLGDTGAERVADADQYADLAALAAAV
AGGSPVPDEVLVHLAPAAAPLTAAAVHRAAHDALALAQAWLADERFAAARLVFVTHGAVP
ATPDEDVSDLAAATVWGLLGSAQTENPGRIALVDAGTGAGTGAGDGAALRAALTGDEERF
ALREGAVLVPRLARVETAEDDAQAGQAGPAGPAVAAPDGPRRAPAFGPDGTVLITGATGA
LGGLIARHLATAHGVRRLLLVGRRGADAPGAAGLTAELAAWGATATWAACDVADRDALAA
LLAGIPAEHPLTAVVHTAGVLDDGILSSLTPDRLSAVLRPKVDAAWNLHELTRDLAPDLA
AFVLFSSTSGLFGGPGQGNYAAANTFLDALAQHRRAHGLPASALAWGLWSVAEGMAGALD
AADVNRMRRAGLPPLTAADGLELFDTAVSLDDAAVALMRVDTDALRPQAAAGTIAPLLRG
LVRGVARRSAEAAGTAAGEGSGPRARLAGLSAAEQDRALLDLVRTQVAAVLGHEGPGAVE
SGRAFKELGFDSLTAVELRNRLNAATALRLPATLIFDYPDPTVLARHLRGELFADADPAA
DAAGAGSAAPAPAAAADDEPIAIVAMSCRYPGDVRTPEDLWQLLTAGEDGITRLPENRGW
DTDALYHPDPEHPGTSYAREGGFLHDAAEFDASFFGISPREALAMDPQQRLLLETTWEVF
ERAGIAPSSVRGTRTGVFAGVMYHDYGARLHSVPDGVEGYLGTGSSSSIVSGRVAYTFGL
EGPAVTVDTACSSSLVALHLAAQALRNGECSLALAGGVTVMFTPGTFIEFSRQRGLAADG
RCKSFAAAADGTGWGEGAGMLLLERLSDARRNGHQVLAVVRGSAVNQDGASNGLTAPNGP
SQQRVIRQALANARLTGADVDVVEAHGTGTTLGDPIEAQALLATYGRDHSEDRPLLLGSV
KSNLGHTQAAAGVAGIIKMVMAMRHGIVPKTLHVDEPTPHVDWSAGAVSLLTEQVEWPAT
GRPRRAGVSSFGISGTNAHAVIEQAPQPAAPAPAPAAPAGPQALEQYGADPAPYPPVVLS
ARGEDALRAQARLLHTRVRTDADLRPADLALSLATTRSALEERAALVAGDRTELLAALDA
LARGEDSAAVVRGTAREHQVAFLFTGQGSQRLDMGRELHAAQPAFARALDEICVELDRHL
ELPLKDVLFGTDAALLDRTEYTQPALFAIEVALFRLLADWGLRPDVLAGHSIGEIAAAHV
AGVLTLQDAAELVAARGRLMQALPPGGAMIAVQAAEDEVLPLLTERISVAAVNGPRSVVV
AGDEDAALALAAHFEERGAKTKRLTVSHAFHSPLMDGMLADFRKVAEGLVYAAPRIPVVS
CLTGAPVTDEMASADFWVRHVREAVRFLDGVRALGAAGVTAYVELGPDATLSALVQDCLP
EDAGAAGPALCLPLLRKGRPETEALTGALARAHVHGIAPDWQAYFSATGARRVDLPTYAF
QRKRYWLDVGLSVEDVLAAGLEAADHPLFGATVPLPASDGLLLTGRLALSSHPWLADHTV
MDTVLLPGTAFVELALRAASEVGCDTVEELAIEAPLTLAEQGAVQLQLAVEAADGTGRRT
LALHARPADAPAEEPWTRHATGVLAPAEPARAFDLAAWPPADAEEVPVDGFYPAAAAAGL
TYGPVFQGLRAAWRRDGELFAEVALDEAYETDAAAYGVHPALLDAALQAIGLTAPDGSDA
ADGARLPFAWTGVRLHAAGAAALRVRITAGASGGVALDVADTTGAPVASVESLVLRPVSA
AQLGEDRGAHHESLFGVEWAKLPLAAAPVPADERWAVLGEDQADFRIGGAPLEAHTDLTA
LRARIAAGAPAPDVVIVPLSGTAGAGGRAAAARTAAHQALALVQEWLAEESLDASRLLLI
TRGTQAAVPGEHVTDLAHAPVWGLVRSAQSENPGRFVLADTDGSDASLGVLPAALAGDEP
QLALRAGEAYAFRLCRTARTETGTQTGTGTQTGTETETGTETETGTGPESGTAIGHPVLD
TAGTVLVTGASGTLGGLFARHLADAHGVRNLLLLSRSGDAAPGAADLTRALNARGAEVTW
AACDAADRDALAAVLAAVPADRPLTAVVHAAGVLDDGIIDSLTPERLDTVLRPKVDAAWN
LHELTEGHRLSAFVLFSSVAGCFGAAGQANYAAANAFLDALAQHRTARGLAGSSLAWGLW
ATEDGMAGALDESDLTRMARAGVGALAPAEGLALFDTSRTLADAVLVPMRIEPAALRAQA
ADGTLPPLLRALVRTPARRAAPSAARAAARAGAEPAGSLQERLAGLTAADRDRMLNELVR
SQVAAVLGHGTADDVDAGRGFLDLGFDSLTAVDLRNRLTAACGLRLPVTLIFDYPSPSAL
AAYIGERLGRDDSARPSVHTELDKLETILSALAPDDTERAGITARLRDLLAKWNDTHSAQ
DNAAEERDIQAATADELFDLLDDELGLS
>A0A231H988|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia cerradoensis|TrEMBL
MSSYRLPDGSIPILLSSDNPDLLGAEAAAIADYLAGHPEVTPDRVADMLFRTRSPRRHRA
LVMAGAQTDVIAALRAVADGHPHPAVVRSERAASAQRVAYVFPGQGSQRPGMGAMLYEHS
SAYRDAVDECDKVFHDLYGWSPRAYLLEADRQADDKALTVQPALFMQMVGVAAMWQAAGV
TPRVTVGHSQGEIAAAYVSGAQTLRDAVRIVTTRAQIVDSMELTGYSMAVLGVDRDECED
LIARQADFVELSVINSRHIIAISGERTAVVDIVETLNAAGKFAKEIRVQYPAHTSFVATA
REPLSGTVSSEMDNAAFLDADIECFGATFGDRLHSGLSIVDYWYLNLRNRVRFDLAVKKA
AAAGATTFVEISEHPTLMLAIQENLSEIPGQREFQALGTSRRTAEDLREFTRNLATVAVH
DANYRWEALREPGDGGVPALPLLDFPNTRMSAKSLWAPFDYARAAHKPLADSDSDDSTVA
PQRVVETWTRLQRRTMVPPRTFAVIDPAGANEDLAAAVRAAAPRQGATVAEPGSGTRPDT
VVVLAPPSSADGPVHDVAEFLGARAWLDDLDGIGDIWLVTSGGEQVVESDLPDPFHAAVQ
AGFRCLAAEHVGVAFRHADLGTGADAAAAAKALLGAIHIAAEPELAVRDGGFYAKRLILD
DTAGDAPLRAEELREVVIVGGTGKLGLDFCAQFAAAGAGRITLISRSGGTAAAGARIAEI
GARYDTEVVVRRCDAGDAEALGALAAEYAASPATLIVHAAVDYEAAAADPDPATIRAAAA
AKSVVLHNLVRMFPRTDDGRVVVCSSLSATLGGRGHMVYSAINRMLDAQAAHYRAEGIRC
SSVQWGLWRAVGADHAEALARISGTGLLPMDPAVAVAAGFAPRAANVLVAAAQWGRIRDL
FSVFGFAPLFAELPEDEPAPVSPVAQPAAAPVPAADVAAGSRDVADSVRDALRVVMGLEP
EEAVDGSVPLVALGLDSLQALDLRKRVEAELRRDLPVTAILGGASLDEVVALLG
>A0A1Q2ZKQ1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MTIDVPDSPAPTLAEKGETLRNRLADLQPAEQHSLLLDLLKEQISRAADGDGSGLVDVRA
PWRRLGVYRQRAQRLRDGMAEATGLRLPATVLFDYPTPLALAEHLRHELLGPGTVRDTAG
VVDGGRAGTADDPVVVVGLGCRLPGDVDSPEALWRLVAEGRDVIGDLPDDRGWDLEGLYD
PDPERHGTAYTRHGGFLKGAEDFDPGFFGIGPREALALDPQQRLMLEISWEALERAGIDP
HALRGSSTGVFAGVSLQDYGPAWHEAPQEAQGQMLTGNALGVVSGRVSYTFGFEGPALTV
DTQCSSSLVAMHLAAQSLRAGECDLALVGGVTVMSTPGMLLEFSRKRGLAPDGRCKAFSA
DADGTGWAEGAAVLLLERLSDARRAGRRVLAVVRGTGTNQDGASNGLTAPNGPSQQRLIR
RTLASAQLGPADVDVVEAHGTGTALGDPIEASALVAVYGQERPEDRPLYLGSLKANIGHT
QAAAGVAGVIKMVMAMRNELLPRTLHVREPTPHVDWSAGSVELLREPVPWPRAGRPRRAA
VSAFGVSGTNAHVIIEEPPGPGPDPEAALLPVVLSARTGQALRAQAKRVAGHLAGHPDLS
LAGVGATLAGRTRFEHRAVAVAADRDELLGALEALSEGRPAMGLVQGEGRPAGDGGKLAV
LFTGQGSQRHGMGQRLYRTYPVFARALDEVCARMDQHLQRPLRDVMFAAEGATDAELLHR
TAYTQPALFAHETALFRLAESWGVAPDLLIGHSIGELTAAHVAGVWSLDDACSLVAARGR
LMQACRSGGAMTAIQASEEEVLDTLTGLDGQAGVATVNGPLATVVAGDEETVARIAAVWE
ERGRGTRRLNVSHAFHSPHMDDMLAAFREVAEAVTYHPPQIPVVSNLTGERAGEEQLCSP
EYWVRHVREPVRFLDGMRCLYREGATGYLELGPDAVLTALGPGCLPEDADGLVMTSACRA
RRPEDRSLLAAFAELHVHGFPVDWQTPYDGPGTDHVDLPTYAFQRRRYWMERPARTAAPA
QEAPRQRRTDPAGWRHRIAWQPVELPVLPSLSGVWLLLVPPLGADEELLSRVAWVVGLLG
GEAVRVDLRADDADRAELTEMLEKQVTTAGGRLGGVLSLLALDTTPHTEHPVLSDGIALT
CALAQAMADLDLDAPLWCATRGAVATDDTEQAVDADQAMLWGLGRTLAVERPHAWGGLID
MPAELDDESLHLFGAALTAPGDEDQLAVRSTGLFAGRLVPAEPADSRTASAVPAASSALP
ADVSATPWRPRGTVLVTGGTGALGAHCARWLARNGAARLVLTSRRGPDAPGAAGLRAELS
ELGAKTVIVGCDAADREQLAAVLGSLPEDQPLSAVVHAAGVMGRFAPLPETDLAGFAEVV
AGKVAGARHLDELLGDTELDAFVMFSSVTGIWGSSGQTAYAAGNSYLDALARQRRARGLA
ATAIAWGPWAEAGMGAGDGVRDFLTRRGLRHLAPEDAIAEMERAVAAGETGLTVADMDWD
HFVQLRRTIRADRFFDVVRPPADGLSAPGESSGESSVDPAARVTDARAALELVRAEAAAV
LGHGSSDDIDPGRRFLELGFDSLASVDLRRRLAAATGLALATAVVFEQPTATELARHIET
LARRAVEERTAPAPSDPPVPGVRDLYRHGCKVGMYSEANRILQAAAKLRPVFHTPEEYDE
KHGVAREVRRLATGPAGATALVCLPPVVAPSGPHNFARLALHLHGLHDVYGLSYPGFGDG
EPLPASGDLIVDTLTEAMARRFADTPIALAGYSSGGWLAHAVAHRLEQRGLAPKAVVLLD
SWFPKDRVPREKVEEQFRNIAVNDGVWGLITDDQATAQGAYLELLEHWEPRPVTTPVVLV
SAQERWFGGTDEDAVSTHDWSPAWDFAYDTVVTEGDHQSMMYEYAQTTAGALREWLRRV
>C6WG03|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / JCM 3225 / NBRC 14064 / NCIMB 13271 / NRRL B-12336 / IMRU 3971 / 101)|TrEMBL
MSDERISVVGIGLRYPDAATTAELWENVLAGRRAFRRLPDERMNLADYHSPDPQAPDRFY
ATKAAVLRDFEFDRVRYRVAGSTYRSTDLTHWLALDTTARALADAGFPDGEGLPRRTTGV
VLGNSLTGEFSRANVLRLRWPYVRRTVAAALAAKGWPDDETADFLDGLEGRYKAPFPPID
EDSLAGGLANTIAGRVCNHFDLRGGGYTVDGACSSSLLSVTTAAKSLVEGDLDVAIAGGV
DLSIDPFEVIGFAKTGALATGEMKVYDRDSNGFWPGEGSGALVLLRERDALERGLRVYAT
ITGWGVSSDGKGGITRPEADGHRLALDRAYSRAGYNLGTVSYFEGHGTGTALGDATEIEA
LSSARRAADPTAPPAALGTVKGNIGHTKAAAGVAGLIKAVLALHHQVIPPATGHHDPHPK
LDGAAVRVPLTAEAWPGDRPLRAGVSAMGFGGINTHIALEAAPGTTRRAGVDERAAALVA
SRQDAEVLLLDAADRDGLAERVAEAAALVPKLAMAELGDLAAALAARLTGGPHRAALVIT
RTEDAARKLDRVRAALAEGTPLFDTADGVFLGEGTAAPALAFLFPGQGSGKGGDSALRRR
FASAEEVFRSAGLPEGGDQVATEVAQPRIVAGSLAALGVLRELGVEADRAAGHSLGELTA
AHWAGALDAGRVLSLATERGRVMAHAGRGGGAMASLAAGPDRAAGLAAGEDVVVAGFNGP
DQTVLSGPADAVDRVCAAARARGVHATRLPVSHAFHSPLVAPAADAMAERLVDYDFGRLI
RPVHSTVTGAPLAPDADLRALLREQITGPVRFQEAATGLAEHADLVVEVGPGRVLTGLLA
DIAPGTPALSVDADSASLAPLLTVVAAAHALGAPIRTAPLFADRVARELPLDGAMTFLAS
PCETAPPLDPALRTTTSAAQAAPGTTAQAEGESTLDLLRRLAAQRAELPLEALTEHTHPL
DDLHLSSITVGQLVNEVTRGLGRPALETSPNFATARLGELADLIDELAATAHDGDRQDGE
APGVAPWVRPFRVVHVERPLRPVQVAEPGDWTVHAPDGHRLTTHLEGALPGDGVLLLLPP
EGGPEHVALALTAARDALATGRRFALAQGALGMSGLARTLHLEAPHLPVTVVDLAAGLPD
HAAAAAVVAEIAAGEGFTQARYAATGARTVPVLRVAEPPAPDAAVPAASPLGPDDVLLVT
GGGKGITAECALAVATDTGAALALLGRADPADDAELAANLARMTAAGVRHRYERADTTDP
DQLAAAVTRFRADLGDVTAVLHGAGRNEPTALPNLTEDAFRATLAPKVDGLRAVLDVVGE
PNVRLLITFGSIIGRAGLRGEAHYATANDWLTELTTDFARRNPEARALALEWSVWAGAGM
GERLGVVEALMRDGITPISTDAGVAVLRRVLADPTAGPALVVSGRAAGLPTLELERAELP
LTRFTDRVVVHYPGVELVTEADLSGGSDPYLEDHQLDGDLLFPAVVGMEAMTQVAAALTG
RAGPPLLEDVRFLRPIAIRPGGALTVRLAALATGPDTVEVVVRAEDTGFSADHFRATVRL
PRPDLPAEPAATATATDPAATATTVPTDPALPPVPVDPVTELYGGILFQGKRFQRLQAYR
TASARRAVAEVATTSAATWFAPFLPQERLLADPGARDVMMHAIQCCVPDAVLLPQGVERL
HLADPAARTGEYVVLDARERSQDGDSYTYDLDVRDPSGVLVERWEGLVLRAVRHRDGKGP
WTPTMLGPHLERALERVLGGSRAVVVEPDPAEGGERRAQTALALSRALGAPVEVRYRPDG
KPEVAGHAVSASHGAGLTLAATAPGGRLGVDVETAAPRTEDDWAALLGRAPLAVRDLLAR
ETGEDPSVAGTRVWGALECLRKTGSTTQALALERVHPDGWVVLSTGDARVATWTTTVDDR
PEPVVFAVLAGQED
>A0A0N0NC65|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OV320|TrEMBL
MSAVDEGALRRLIAERVAARIGTGDDVPMDLPLADLGMSSRDAVGLAGELSRLTGRELPA
TLLWSAPTLEALVAQLRGPAERHLPAAPAAPFPAAPDEPVAVIGVGCRLPGGVRGPADYW
RLLGDESDAIGPVPADRWRDFTAFPPADAPASGGYLDDIAGFDADFFRITPREATVMDPQ
QRMLLEVVHESLDHAAVPAAALAGTATGVFVGVCATEYGRLTGARAEAVDPWAPAGAALG
VTAGRLAYVLDTRGPSMAVDTACSSSLVAVHHACVSLRTGESDLAIAAGVNLLLSPVVGV
AFARAGALAPDGRCKPFSTAADGIGRGEGCAAVLLKRLSDAERDGDRVLAVVRATAVNSD
GRSNGLLAPNPAAQQALLSTAYARAGLAPALIDYVEAHGTGTPLGDPIEAGALGRVLGPG
RDPDQPLLLGSVKGNLGHLESAAGIAGLVKTVLALHHDRIPPSLHCAHGSALEDVTLRVV
TEPEPWPRYGGTATAGVSAFGFGGTNAHAVLEERRPDPLPPPPAEEPTARLHLLSDIDTE
RVRDTAARLAGWLRTPGGRAARPADVARTLAGRTGRGPVRAAVVAHDREELADSLDALTH
GRPHARVLTGDCDRIGPGPVWVFSGYGSQWPGMGRRLLAEEPAFAAAVEKLDPRLAVACG
FSLHDKLASGAALDRLEIAQPVLFGVQLALAELWRSYGAEPAAVIGHSMGEVAAAVCAGA
LDVSDGARVVAARARLLSGLHGGAMAVVDLEDGELADLERDFPGVQVAVHSSPRQKVVTG
DEGTVTRLVRRLAERGRAARAMRVVGAGHSPQVDPLLPELTEALADVRGGPARVPVYSTV
LDDPRGECRFDAAHWAANLRRPVRLDRALAAAGADGHTAFVEIAPHPVLARPVTDTVPGA
LAVGTLRRDADGCAGFLSELGALYAAGLPLPPPPGRVVDVPAPRWRHTRYWWTDGRSPVA
AAAAAAGRWAEPAAPGAQPDGPASVAARLSHHIAAVTGHPTARVTPATTLAELGLDSLMA
VRIRTALEREFRVDLPLRDLLAAATVDEVADRVRQALRASEAAGDETELPAPLRALRTAG
SRPPLFLFHAAGGRADVYRALAERLGDDRPVHGLERLEDARTVPEKARRYAEAITAAHPD
GPLLLGGWSFGGFLAQETARQLTAAGRAVPLVVLIDSVRPLLRPGRTQADRLRAHFTGFA
RHVADTYGVSLRLPYDELAAMDDDRERIDLVLRTLRGAVGVPAAALAHQRASYLDLRVGE
AHRPGRHDGRVVLYRATEPAPHTVRDPAYERDDETLGWDEVCPRLTVVPVPGHHLSLLDP
PHVDEIAAHLGRLLATPSGPAEPD
>Q3M5M8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Trichormus variabilis (strain ATCC 29413 / PCC 7937)|TrEMBL
MITNDNVEFSTLVDLLRYRAQNQPTQTAYTFLVDGETESISLTYQELDQKARAIATQLLQ
RGVPGSRALLLYPPGMEFIPAFFGCLYAGFIAVPAYPPRRNQKMSRLQAIVSDAEAVVAL
TTSTELTSMALQLAENPTLTAIPWITTDNLNANIAEDWQQPNINSDTLAFLQYTSGSTGT
PKGVMITHGNLLHNSQLIYNFYQHTPNSQGVIWLPPYHDMGLIGGVLQPLYGGFPVTLMA
PVAFLQKPFRWLQAISHYKATTSGGPDFAYDLVCRQITPEQLASLDLSSWEVAFTGAEPI
RAQTLDRFAETFAPCGFRREAFYPCYGMAETTLIVSGGWKSEAPIVRHIDTTALLQNQVI
DTTTAAGGKAIVGCGKSSPDQTVLIVNPESLTSCADGQVGEIWVSGSSVAQGYWNRPEQT
QHTFHAYLADNTTGPFLRTGDLGFLQDGELFITGRLKDLIIIMGRNHYPQDIEFTVESCH
PALRPAGGAAFAVEVNNVEKLVIVQEVERSYLRKLNADEVIGAIRKAVAEHHDLQTHTIA
LIKTNSLPKTSSGKVRRSNCKAELEAGSLDIIAQWSADAQNHSPSEKLIAPQVEKTVNTE
AVATWLLTKVSEQLQVPAQTINVNEPLAQYGLGSLAAVRISGELQEWLGRELPTTLLYDY
PSIAALAQYLGDGVPQPKVVSQQPTDNHAIASGGAAPIAIVGIGCRYPGANNPEAFWQLL
RNGVDAISEVPQQRWDVNSFYDPNRATPGKMNTRWGGFISEVDQFDAPFFGISPREAESL
DPQQRLLLEVCWEALENAGKAPSKLAGSNTGVFVGISNFDYSQLLAKQVSGLDAYSGTGN
AFSIAANRISYLLDVHGPSWAVDTACSSSLVAVHQACQSLRQGECEMALAAGVNLILTPQ
LTVTFSQAGMMAGDGRCKTFDADADGYVRGEGCGVVVLKRLSDAYRDGDRILAVIKGSAV
NQDGRSNGLTAPNGLAQQAVIRQAMQNAGVAPHEIGYVEAHGTGTFLGDPIEVNSLKTVL
APGRAPGDTCVIGSVKTNIGHLEAAAGIAGLIKTVLSLHHEEIPPHLHLKQVNPHISLAD
TNLSIATTLLPWNRGNKRRLAGVSSFGFGGTNAHIILEEAPLVSPKDTVSDERPLHLFTL
SAKSENALRDLAKDYENYLGNHPDASLTDICFTANTGRSHFDHRLVAIAQSNIQLQTVLG
AYATGKKTSQLVSGKIENKQQPKIAFLFTGQGSQYINMGRQLYATQPTFRAAIDQCEQVL
RSYLDQPLLSVLYPDTESSCIDETAYTQPAIFAVEYALAQLWKSWGVEPTAVIGHSFGEY
VAACIAGVFSLEAGLKLVTERSRLMQALKSMGAMAAVFASEEQVQAAIAEYSPEVTISAV
NAPDNITISGTVAKIAAAIAKFTAQGIETRRLNVSHAFHSPLMDEMLDAFEQATNLVNFQ
APQIPFVSNVTGNFLPVGQVPDAQYWRSHTRQSVRFMDGLNTLLAEGYELFIEIGAKPVL
CSLGKRCHGGENSVWLPSLNAKRDNWQTLLESLSTLYLRGVEIDWAGFESDYSSQLVALP
TYAFQRKRYWIQSPNRVDNIPVNHHSNNSQPVTSASSDSAKLPSQALVEKMLKQQLQIMS
QQLEVLRTHNLTKGQFLPLQHGHLPKPPKLNHQPSI
>A0A378SRM7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium gilvum|TrEMBL
MLPDGRIPVLLSAHAEELIGEDARRLLGFLDSAPEVDAVAATLLRVRRRNRHRAVVRAAD
RSELADALSALAAGQEHPLVSRSAEPDAHRRAFVYPGQGNQWPAMGAEAYRTLRDYRQAA
DVCAAAFTAAGAPSPLRYLTDAAAVTGSQVEAQAAQFTHAVALTAVWRAHGVAPDMTVGH
SLGEVAAAHVAGAITLAEAAAVVIARATVLEGLADGYGMAVLGLTPEDAQSLIESVPGWL
ELAVVNAASSVGVSGERDAVDALLAQASSRGVFARSVTMAFPAHTSLLDGLRADFVRLLA
PARFQQTAIPFLGSATGEAVPPETDFADYWFANLRNTVRFDRAAAAAVRAGANLFVEMSA
HPALLFSLGQSAGDALTVGSGRRDAPLVETLSAGIATVAAHDAEFPWHDVIDTTRPALRG
FPNAPMRSVHLWALPQPLPAPPSLTLATEAWEPHRPAERGLALRRTAVLDLAGPRGGLGD
LLRDAVDHHPGMVSTPVHDADLVLAVAPNLGDPDVRESVAALTALIDDGLLRYPDDVGTD
CRDLWLVTTAAEQLTGDPTPRPAQAALAAMHRSIGFEYPDRAFRHLDLPPVVLDEAAASA
ALDAVLGGGDDLALRDIDGMPAVFARTEHETVTTPESWADDPGALDHVVITGGSGTVGQH
YARHLAERGARRITLLSRHGAMGSAASGPGVQTVCCDVTDPVALAVAAAEFGGDGATLMI
HAAGTAQFAEHDTLSAAAFADTAAAKVEGLFRIAEAWPRRPGARMLVCSSVSGLWGGRGH
AAYAAANRLVDVTAAQMRAEGIRCAAVRFGLFGTGIVDEESVNLIGRSGLVPLDPDDAVA
ASLRDLPGDPIVYSADRARLQIFRDDPAPPTATSPASGGDTTAVVLAELTSVLGIEPAGV
DLDASLLDMGVDSLLALDLRKRLRRATGRSVPLAAMLGGMTGAELITGLDDEPQRNEIPA
>A0A2K8RKH2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MGSVRRKPVIAAGVNFDTPLSGIPLDGLKLQVVTGRGSWRGDRRVAGVSCFGLGGADCHV
VVAARFPEGFAAPASPGRAAVSGRAAVSGAVPVVVSGRIPAALRAQAARLADWVDGHPGS
GLVVLGGCLLSFCTLFDHRAVSLGADGLRVLAAGGVGDDVVIGRVTVVVCRMVFVFPGRG
SQWVGMARELVGGSLVFGARMDECGRVLELFTNWRLADVLGGVDVLECTEVVQPVLWAVV
VWLAAVWQSLGVVPDAVLGHCQGGVAAAVVAGALLLEEGACVVALRAGTLGALAGCGGVT
SLVLSARGARALVGPGLSVATVDGPSSVVVAGVPEVLAVLEALAGEWDVRARRLPGSCAP
AECTDQDEGRVGGSGA
>A0A291SKX4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces malaysiensis|TrEMBL
MADSKTLTDYLKWVTADLYRTRERLAEVESASAEPIAIIGMACRFPGGVTSPEALWELVS
SGTDAISGFPDDRGWDLEGFFDSDPAQEGTSYMREGGFLTNATGFDPAFFGISPREAVAM
DPQQRLLLETTWEVLERAGIDPTSLRGSRTGVFTGLMANSYTTRVRRIPGELESYAGNGE
AASVASGRVSYTFGFEGPAMSVDTACSSSLTALHLAVRALRSGECPLAVAGGVTVFATPR
IFSDLSRQRGLARDGRCKAFSTSADGTGLSEGVGLLLVERLSDAQRLGHPVLGVVRGTAV
NQDGASNGLTAPNGPAQQRVIKAALADARLTAADVDVVEAHGTGTKLGDPIEAQAIIATY
GQDREQPLWMGSLKSNIGHSQAAAGVAGIIKTVMAMRHGVMPKTLHVDEPTPEVDWSAGA
VEVLAEARDWPGADERPRRAGVSSFGVSGTNAHVILEQAPPAPEPTESAEPVEPSETAEP
SGPVGLELEPSGPVPWVLSAQNETALKDMARQLVTETEGSVHQIAHSLITQRSTTLPHRA
VLVGSTREEFTTALDNLTGHTFDGGKTVLVFPGQGSQWVGMGQRLWETSPLYRDTIHEVD
TALSEYIDWSVTDILTGQPGAPTWDRVDVIQPVLFTTMVALATLWQHHGLTPDAIIGHSQ
GEIAAAYTAGALTLQDAARITTLRSKALLPLTGHGTMISVLAPPEKIQQIANPDHWNTRI
WIAAHNAPNTTTITGDLDAITHLTQQLSHHRIMRWQLPGVDFAGHSGHIDQLHQQLQEIL
APITPQKPTTPFYSTTDNTWITDTTLDADYWYRNLRQPVLFQPAIHHLTNNGYTTYIETS
PHPTLTPSIQETNPNTTTIHTLRNEHDDTHAFLTALGHAHTHGHPITWHTLIPPTKTTPL
PTYPFQHTHFWLNEKTADADVESAGLSRTDHPLLGATTTLAHSGETVLTGRLSPTQHGWL
ADHAVNGTPLLPGTALVDMALHAGDHTNHTTLDELIIHTPITLTHPTTIQLTINPPDDAN
TRALTIHTSDNPDGPWTAHATGTLTRANTTPPSPQTTWPPTDAEPIDLTGTYQRLATTGL
EYGPTFQGLHALWRRDSDNRLLADVRLPDSIDNTDGYGIHPALLDAALHALVAVSDGDEI
RLPFAWTGVTLHATGATKLRVELDIDDDGTLSLSATDTSGQPVVTVDSLTTRPIDPAQLR
ARPRQTDDLYALDWLPWSGSVSPTSEFERYAVPTVGDDVLADTHRITTETLTHVQQHLAQ
DTTTPLVVEATYDDLAGAAVWGLIRTAQTEHPGRIILIDTDNHPTSRKALPTLIASGEPQ
ARIRDGAITLPRLTTTAVTDALTPPADADAWHLDTSEHGTLENLTLVPSDSATRPLGPHE
VRVAVRAAGLNFRDVLIALGMYPGEATMGSEAAGIVLDIGPDITDLTPGDRVTGLFPDAL
ANVVIADRRTITPIPADWSYTDAAAFPIVYLTAYYGLHDLAALKPGERVLIHAGTGGVGT
AAIQLAQHLGAEVFATANPTKWPHLRAMGLDDHHIATSRTPDFETTFHTTTQGQGIHVIL
NSLTDNLTDASLRLLTPNGRFIEMGKTDLRNAEDLPEGITYQAFDLALDAGADRIAGMLA
ELVELFGSGALSLPPVRCWDVRESVDAFRFMAQARHIGKVVLTIPHTPDGTILITGGTGN
LGSLIAHHLVTEHGVRDLVLTSRQGPNAPGATELTNQLQQHGARIRVRSCDLTDRTALAT
LIDDIGPLTGIIHTAGALADTTIDHLTPDTLTTTLTPKANPAWWLHELTQDHDLALFVVF
SSSAAVLGSPGQANYAAANSFLDALITHRRRQGLPGTSLAWGWWQRTGAMTAHLTQADHD
RMTRAGLYGITEAEGTALFDTALGRGLGAVAPVKLHLPTIARSGSVPPVLRALVRAARPT
ASQAAVQDGTWADRVTAVAPEERRAVVLELVRAQAATVLGHSGAEHVSPTQAFKDSGFDS
LTAVEFRNRVTTATGLRLPATLIFDHPTPNTLADHLLAQLAPADTGPSLADLDGIEVTLR
ALAEDGERRPTVVARLKQWLSTLGAAQPAADTALDLDAASAREIFDFLDGKAG
>X5DXX6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Corynebacterium glyciniphilum AJ 3170|TrEMBL
MSETSGTSETPGNENTRAAEPAPTTAAGMRGWLRDWVQSTTGLDAADITDDRPMEEFGLS
SRDVVVLSGELERLTGVSLDATVAYEYNTIAALAGFVLAGGTRAARGVAGGRRTQRQDGA
RGGGLNPEDRQIAVVGMAGRYPGADNVDAMWRMFEQGRSGVGELPEGRWSEYGDDPEMSR
RMAEAILTGGYIDDIASFDAEFFGLSPVEAANMDPQQRILLSLTWEALEDAGIPANSLRG
SDVGVFMGTTNNDYGMLISADPTEAHPYALTGNSSAIVANRISYAFDFRGPSVAMDTACS
SSLVAIHQAVRALRDGDASVAVTGGVNLLASPFATIAFSELGVLSPTGGIRAFSDDADGI
VRSDGAGVVILKRLSDARRDGDDVLAVIAGSAVNQDGRSNGLTAPNPEAQAAVLDAAYAD
ADIDPSRVDYVEAHGTGTILGDPIEAGALGQVLGADRDVASPLLLGSAKTNFGHTEAAAG
VAGVIKVVSAMRRGVLPPTVNFTGPNPYIDFDRERLEVVEDPREWPEYSGAPVAGVSGFG
FGGTNAHVVLVAPEGAAPAEDAAAPLPDVIDWAGVQESTDEAGAGRPLPRLIPVSGLLPS
RRRTAAADLASWLEGRSGNAVLAGTAVVQGDRNHGRSRGVVLAHDTAEAVAGLGRLAEGK
KGAGISVADSPEREGAVWVYSGFGSQHRKMGKELYALSPQFAARLDEIDQVVQRESGFSV
VEMILDDAQNFGTETAQVGITAIQIALTDLMTGLGLRPAAIVGQSMGEIAGAYAAGGLSM
EDAATVACHRARLMGEGETLLPEDKQGAMAVVELGVEDLVEFQKEHPQFAAVEPAVYAAP
GMTTVGGPAQPVADLVDHLDGQGKFARMLKVKGAGHTSMLDPILGELHAEISGITPRPIH
TPVYSSVDRGVVYHPGAVLHDADYFLRCTRYSVWLSDATGLLFDEGFRTFVEFSPNPVAL
MPMMNTAFAHNAGESSLMFLLKRKEPSIDTLLATVGELYVRGADVDFRRLNSVDGDPAQR
GRAVVDIPGVHWNLQRYWTAARPGGGSVRGIPGRRVALPDGRTAFAVAAAEVPSVDAVAE
AAARAVVPDAVTAAVETYGTLPTDGEVTTLVTRTLGGLSVHVYAMDGADGTGGAGESRLA
GEAFAASPTTGVAAAASRAVQEAQDGQAAGNPVRPTGAPGPSSGRNSLPAVDTDAERWSP
ESGESVADRLRSIVSESMGYDIDDLPGELPLIDLGLDSLMGMRIKNRVEYDFALPPLNVQ
ALRDGSVDEVIALVEQMVHENATEAPAARSAERTGNGEGVGVAPRDASERMVFGTWASLT
GAAPAGVTSTLAAIDGETAAAIAARLSERSGADITAEQVSAAQSLEPLANLVRDVFETSV
EGNIRVLRARPEGSESPAVFVFHPAGGSSVVYEPLTRRLPVDVPVYGVERLEGSLDERAD
AYVADITALAEGRPVVLGGWSFGGALAFEVAHRLEKAGDVKVGHLELLDLVRPANPAPDT
TEEMHARWDRYSAFAKKTYGIDMPVPHDLLENQGEEALIGMMSMFLQNTDASSHGLAAGV
LEHQRASFVDTRILNTLDFERWAEVTAPVTLYKSEGMHEGAIELEPSFADIPADGGWDGV
VDDLELVQLAGDHLAVPDEPSIGIVGARITEHLRDISERN
>K9XRL8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Stanieria cyanosphaera (strain ATCC 29371 / PCC 7437)|TrEMBL
MTQDAIAIVGIGCRFPGAKNPQAFWQLLRKGGDAITEVPKSRWDVDQYYDPNPSKEGKAN
TRWGGFLEDIESFDPLFFGIAPKEAMTMDPQQRLLLEVAWEALEDGGQIPAKLAGSQTGV
FIGIGTHDYSILMWQNPVSEPYATTGTGNCIAANRLSYIFDFKGPSLAVDTACSSSLVAI
HLACQSIWNGESTMALAGGVNVLLLPTIVVGFAKGGFMSADGKCKSFDADANGYVRSEGA
GIVVLKPLSQAQSDRDRIYAIIKGSAVNQDGFSNGIAAPNPDAQEAVLRKAYRRAGVAPN
QVQYLEAHGTGTKLGDPVEMEALGRVLSENRSFEDYCAIGSVKTNIGHTETAAGVAGLIK
VALSLYHREIPPSLHFKQPNPAIDFANLPFQVQTKLTPWREEKEMIAGVNSFGFGGTNAH
VVLSNAEGRGQVQRGKEEKKYFFNLFTISAKSERALKDLVVNYLEFLDCNPDISLTDLCF
TANARRTHFNYRFAIVTESIPELQLQLNNFVSNQETTGLFSGQKKIDINYQNPIAFLFTG
QGSQYVGMGQELYETQPIFRDSLNHCAEILQAYLDRPLLEIIYPDNAVETFHRTSLQDVN
QTQYTQPALFAIEYSLAQLWMSWGIKPTVVMGHSIGEYVAACLAGVFSLEDALKLVAVRG
KLMQSLPQNGTMASVLASEAKVIKAIQDYQNEIAIAAINGYQSIVISGKSNAIAKIINQL
EAEGIKTKPLNVSHAFHSPLMQPMLVEFEQVAREIKYSNPQINLISNVTGKLITEAITTP
EYWCQHILQPVRFVNSIETLFNFGCEIAIECGAKPILLGMTSAILEKSNNNSFLNLLPSL
RPPQSDYQQILQSLGQLYTQEIKINWSSLYQANFHQIVSLPTYPFQRKRYWWEGIKLPVE
QISFAAGKQLKSSQLHPLLEQKIYLASSEEIVFQVELSPDNPFYLKDHCLGNTVIFPATG
YLEMALAAGANLYQINSNILIKNFLIEQALVLSFDENKIVQIVLKPQSDSEYTWQIFSLN
ESQAKFTSHATGKIKLVTQTKKHFYKNIKQLQQNCLDNLLSIKDYYQQLQQQGLNYGKNF
QALQEIWQSEDKVFGKIQLPDDLISEANQYQLHPVLFDACFQLLGTAIKQQKTGSYLPVG
IENLYFYCQPNHCIWCQVEIKPSNNSQSVQADLVLLNSNGLILAKVQGLLLQYVNQQSLT
KLTQTKINKLNLSEHLYQLVWFPNSNHNIAQKSKDTEERKERFISLEATEYQVCVDHWLI
FADRYGVGEKLAEELEKSDRSCLLVFPKALEDCVEDTNFRYSLDRNSREDWQKLLKDYVQ
TNIGIVFLWSLDETEDFVTTQQQGCGSVLYLIQSLLENKSLQVAKLLLVTQETQAVTANQ
ASLQVQHSSLWGLGRVINTEHPQLNCTLLDLDGFDPVTCVLSELNSIQQEHQVAYRQGNR
YVARLDRYKLLTKTNQESFRLQISDYGMLDRLAIVCDRVNSPKPGEVTIEVCAAGVNFRD
VLNALGMLQEYLTSMGFTNASDIPFGGECAGRIVAVGEGVTEFQIGDEVIAAQAIGSIAS
HVVVNANFVIAKPTQLSFTEAATIPTTFLTAYYGLHKLAQIKAGDSILIHAAAGGVGLAA
IQIAQQASAEVYATASLSKWDFLKSIGIKYVMNSRSLDFAEEIKQLSAGKGIDIVLNSLN
GEYISKNLDILASGGKFVEIGKLGIWDESQIKAKRNDVAYYLFDLLEVSQQNPSLIKQML
GELMQQFRLGKLKPLHHQVFPITEAESAFRHMAAAKHIGKVVIDCKGGLQTALTQINDQG
SYLITGGLGALGLQVARWLVDKGARNLILVGRSKPNSEAKVIIQQLEETGAQIEVIQADI
ANLEAVNRIVRANSSSPLLKGIIHAAGIIDDGLLQQLSWERFAKVISPKIMGAWNLHLAT
QNLPLDFFVCFSSITSILGTFGQGNYAAANSFMDALMHYRRSFGLPGLSINWGLWDDLGM
AASLNAEVKARFSDEGLETIELNSGLELLEQLLLQNHSQLAVFPVDWSKFLSAKPENTFF
QLFKPKSEVKNQPISNLNPIFSNISAFQQHIQTQVAKVLGFSDRKSVDVQENFADLGMDS
LMAVELKNQLQTSLKIDIPLTITFDYPTVEALANYLFEKIAGEDNSYQLSVTSYQLPLIE
TEEKTSPWFNTEVVDHNRIETKEKLEPIDKIEIKPEFCDFKFLPQYLTLKQDLNRVEAMG
NPFFTIHDGIAKDTTQIQGKELINYSSYNYVGMSGDPIVTQAAQNAIAQYGTSVSASRLV
SGERAIHGELEREIADFIGTEDCIAYIGGHATNVTTIGHLFSDRDLIVCDSLSHNSIQEG
CKLSGATKIEFPHNNYQKLAEILAQHRYSYEKVLIAIEGVYSTDGDLAPLPEIIEIKKRY
QTFLLVDEAHSIGVLGSTGRGISEHFKINPADVDLWMGTLSKSFASCGGYIAGCRELIEY
LKYTSPGFVFSVGMSPANTTAALKALKLLKIQPERVIRLQARSRFFLELAKSKGLNTGAS
KDSPIIPIIIGEPYKAVQLSQQLSQQGINVQPMVYPSVPYDAARLRFFMTCLHSEAQIEF
SLNSLVRILKNNFK
>A0A378UUP3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium fortuitum|TrEMBL
MSSSRRPPGPENADPVVIVGMALEAPGGIDTADDYWSLLAEQREALGRFPTDRGWAVRDL
FEGSRRDGFKRIHDLGGFLSSAASFDPAFFGISPREAVAMDPQQRIGLRIAWRALENGGI
NPDDLAGHDVGCYIGASGLEYGPPLSEFSHHSGHLITGTSLGVISGRIAYTLNLCGPALT
IDTSCSSALTAFHTAVAAVRAGDCDMALTGGVCVMGTPGYFVEFSKQHALSDDGHSRPYS
AHASGTVWAEGAAMFVLQRKSAAVRDGRRILAEIRATAVNQDGRTTGLTAPSGAAQQRLF
AKAIEQAAVRPEDVGMIEGHGTGTRLGDRTELRSLAQTYGATAPGTGALLGSVKSNLGHS
QAAAGGLGLAKVILAAEHAAIPATLHVDEASREIDWDSQGLRLATKLTHWPAVNGQRIGA
VSAFGMSGTNAHAIVSVPEPPEAVA
>F8L501|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Simkania negevensis (strain ATCC VR-1471 / Z)|TrEMBL
MKKADQNGIAIIGMSGRFPGAQNTEMFWNNLCQGVESIMRFSDEELPKSDLEKPNYVKAR
GTIENITDFDADFFGMSRREAELTDPQHRLFLECCYQGLEDAGYAPGQYNGAIGVYAGAS
SESNYYYNILTHSDACKESEKNLLRLGNELDYLTTRVSYKLNLKGPSMAIQTACSTSLVT
VCMACSQLLTHQCDIALAGGATISIPQERGYQYQEGMIFSSDGHCRPFDAKSGGTVPGNG
VGVVVLKRLDEAIRDRDHIYAVIRGFGLNNDGSEKIGYSAPSIEGQASALRRAFKMAGIA
PETVSLIEAHGTATLLGDPIEVQALSEVFGTGKRKQCAIGSVKSNIGHLMETAGVAGLIK
AALAVHHKTLPASLHFKEPNPHIDFESSPFYVVGETKPWEETPRRALVNSLGFGGTNAHV
ILEEPPEVLKREERHQDYLFVLSAKTKTALQAMSDRLKSYLEKHPDLDLGDVAYTLQVGR
AAFPQRKAFVATNREDAMKQLATRDEIGEAKTELERMGLDWMRGESIDWTHLHENDGCRR
ISLPTYPFEKKRYWLEFNAKEEANTPSDNVQDTLKRIWKEYLGLDQLTVNDNFFDLGGDS
FLAIQMVPEIQEVLGVSLKVNTILQYPTIEKLSTFIEKERGTSADREAVLLKEGDPTCSL
FVIHQIDGHIFSYKQLANVLQDEGQIYGIESPYSSSDSSLTIERMASDYVKMIKMVQPKG
PYRIIGASFGGLVAYEIAQQLDVDSLTMIDIINPTHLKQGAETEDDMFSLLLELFSGKKL
SPEELKELSREEKIRQIMQCMNFEILPFLEQERIFECMKVHWGALKKYRPKCYTKRICFF
ETEEKLSSLHDISLVSTWKDLGCNKIEPHVIAASHLGIMTSPYVDEVAKLIDAFLQSQKK
ESPDAKI
>A0A7X5X8Z7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces malaysiensis|TrEMBL
MTSVGHAPEKLMSLPALLARRATENPDGLAYCYLRNGEDPDDRVTYAELRRQALVRAAEL
RRRDMRGRGAVLMYPTGLEFVRAWLGCTAAGVMGAPVQVPRNGQALRRLRSVADDSGTTW
VLTTAETRDRLLADFPGAPELRGLELLATDEFPEAAAAGEPLPAAGPDDVALLQYTSGST
GTPKGVMVTHRNFWHNAAETDALWPTRGGTVVSWLPLFHDMGLLFGVVLPLWAGIPSYLM
GPEAFVRRPARWLEALSRFRGTHAAAPNFAYDLCVREAPPAPGCDLSAWRAAVNGAEPVR
LHTVRAFIEAFTPYGLDPRAVSPGYGLAEHTLKISGSGPGEPPRALTLSPGDLGEGRVTE
TTDAAAVPVVSCGRTIGGTRVRIVDPATGRAAAPDRVGEIWATGPCVAAGYAGRERESEE
TFRARIADDADTAAFLRTGDIGFVRDGELYVTGRLKDLLVVKGRNHYPQDLEYSAERSHP
ALRPASAAAFAIDRGDREALVVVIEADGRALRAAGHDVLVSAVRERVRSDHRLEAEDVVV
IRRGTLPKTTSGKVRRGTCRQQYVDGTLVRVGGGPA
>D3Q134|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Stackebrandtia nassauensis (strain DSM 44728 / CIP 108903 / NRRL B-16338 / NBRC 102104 / LLR-40K-21)|TrEMBL
MDESKERKLRDYLKRVAAELTETQQRLAHFERRDHEPIAIVGMACRYPGGVETPEDLWDL
VDGEREALSDFPDDRGWDLDSLIDTEGKTPGTTYVGQAGFLHDATDFDAAFFGISPREAL
GMDPQQRVMLEISWEALERAGIDPASLKRSNVGVYTGLTNSGYETPLAETPETVGGYMVS
GNNGGVASGRVAYTLGLEGAAVSVDTACSSSLVAMHFAVRALRGGECDMALVGGVSILAA
PDAFADFARQRGLAKDGRCKSFAAAADGTNWAEGAAVLVVERLSDAQRRGHRVLAVVRGS
AINQDGLSNGLTAPNDLAQRRVIGSALADARLSAREVDAVEAHGTGTSLGDPIEARALLA
TYGQGRDEQDPVWLGSLKSNIGHSTAAAGAGGLIKMVMAIRNARLPKTLHVDTPSPHIAW
NSGAVELLTAARPWPRTDRPKRAGVSSFGISGTNAHVIVEEAPEAAGPEPDAGPHPGLWT
LSAKSLAALSAQARRLADRVEADPGLRPVDIGYTLATARSQLDYRAVVLATDRETALSGL
RQLAEGERSEAMLRGRAKQRTEAVFVFPGHGSQWQGMAAGLLGASPIFTAKLAECDEALS
SHVDWTVTSVIRGDDGAPSIERGDVVQPALWAVTVSLAALWEHAGVTPAAVVGHSLGEVA
AATVAGILSLADAAKLVTRRAEAVREAMGKGAVAVLRADEERTRELLRPWADRLYIGGHN
SPRSTTVSGDVEAIDDLLAHCESQGQWARRVAMDYASHSPHVETGRDFFLNSIKDIEPRA
PRVPFYSSVRGEMTSELDAEYWYANLRQPVRFDLAVRALLDDDHRGFIECGPHPVLSHGI
GETAAAAEVTATIVETLRRDEGTAVKFRSSVARAWVNGVNVDWPSMYAAAGARFIDLPTY
PFQRERFWLRDNVSAATPKPVPAVRAPAPPAAEPEAGTTGDLLTMVRTEAAAALGYASAE
DVEADDDFQELGFDSLAAVELRERLVDATGLTLAEEVALEYPTPVALARYLAERLGGDTG
GSVPEPVSGPGAGLAGLFVRACADGQIVEANDLTLRMAAFREKYSGVSASPPRATTLTKG
TAEPVLVCFPSFAWKYSPYYYAKLAASFEGGQSVIAVDLPGFAGHEPLPSTLDDLIATLA
DAATRAAAGRRFALLGHSEGGRLASLVAEYLEDQGEHPEAVILLDTIEWVTDIDHNETLK
ALYRLLVEQVDTRQPTSDGEAWITARAQYLTFEFPTPRPKAPSLLMRATGRLPGWRNEDA
RSEVRWEHTAVDVAGDHFSMLAEHAPESARTVANWLSDSIGDQKA
>I8TNB6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pelosinus fermentans JBW45|TrEMBL
MANQAVTAIAQEMLHEKAITYFKKLLSSVIKLPANRIEVDAPMEKYGIDSIMIMQMTNQL
ETIFGSLPKTLFFEYQNIQEITGYFLESYRDQLIELLGVEEKATETTEKYEYAITEVEPA
KSSVSSRRRSFFASQRMKAPQEKSEQDSDIAIIGVSGRYPQAKNIQEFWENLRAGKDCIT
EIPQDRWDHSLYFDEDKDKPGKTYSKWGGFLDGVDKFDPLFFNISPREAEFIDPQERLFL
ECAYETLEDAGYTRETIGTHQGFGLEGNVGVFVGVMYDEYQLYGAQEQIQGRPIALAGNS
ASIANRVSYFCNFHGPSMTVNTMCSSSLIAIHLACQSLQRGECEFAMAGGVNLSIHPNKY
LALGQGKFVSSKGRCESFGQGGDGYVPGEGVGAILLKPLSKAIDDGDHIYGVIKGTAINH
GGKTNGYTVPNPNAQASVIGRAFKKAGINPRTISYIEAHGTGTSLGDPIETAGLTKTFQE
YTKDKQFCAIGSAKSNIGHCESASGIAGVTKVLLQLKYRQLVPSLHSEMLNPNIDFGRTP
FVVQQELTEWNRPVIEIDGEIREYPRRAGISSFGAGGSNAHVFIEEYIAKDQPLSTMITA
RNPAIIALSAKNKKGLKEQAQQLLAVIGEQQFSDKNLADMAYTLQVGREAMEERLAVIVG
SVKELEDKLQGFVEGQDDIDDLYRGQVKRDAENMSVFTADEDMKKTMEAWMIKGKYAKIA
EIWVKGLIIDWNKLYGNSKPSRISLPTYPFAKERYWVPESNTIPNNKITSSSNVALLHPL
LHQNTSDLSEQRFSSIFTGQEFFLADDVVKGQRVLSGAIFLEMARAAVEQGAGVLAEDLI
EIRLKNVVLGCPVAVGHQPAQIHIGLYPEENGEIAYEIYSESEDTDAEPIVHSQGIAVLS
SLEKVSTMDIKALQAECSQNTLTSSSQNYETFRTAEIEKVYIGSDQVLVKLYLASPVVAD
QNQFVLHPNVMNVVLQNLVSFMPGTDDFKPVLPIALQELEIIENCAFAMWALIRCSEGMA
VGDKERKFDIDLCDEQGNICVRMKGLRTQGIENVVQELLPSPPSMAVPNTQEAFEMMSFE
EIWQEQALLTTTPTKIKTLVCFISKPENQQTIMEEIENLDQETKVIYISQGTAFEKQSQQ
NYSVARTDLSTYKEAFDNIREDYSEVDAMLYLWPIEDSSCIQDYSSLVYILQAIAGSKLN
TKRLLLAGQFANRLERCYLESWIGFEISLEFVLPNMQVAAVYKEAYPENKERAIRDWLNT
IWTELQADKIQSVLYQGGKRSVHRSQATAMQANSSLLRAGGTYLIVGGCGEIGFLFAKYF
AQKHPVNLILTGRSPKNEDKQAKIKILEDLGSQIMYIEADVCDASGMKEGLSRAKERFGK
IHGVIHAARIESKQSIFEKDIQGFQQVIAPKITGTLVLDEVLAAEELDFICYFSSSSAIL
GDFGSCDYAIGNRFQMAYAHYRKEEQRHGKTVVINWPLWKDFGMDADENEHIKMYLKTSG
QRFLEAEEGVAIFEHILAQHQTQHLVVVGQRSRVHRFLGLAQNQSASSPQALTSPAVKGR
RAEMIGLDAEQCLEWDLKEYVSKLLKISRDKLDREINLVDFGFDSVGLSQFAKLLTSHYG
IEISPAIFFGYFTIEKLIQYFITEHQELIQNYYEEDTIQQSISQKVETIAVKPKQHRNKK
SRFNRNSASPSGLEPIAIIGMSGRFPDARNIDEMWKIILEGQDVVKENSEDKFWGMGFGS
NKWKCGWIPGVKEFDPLFFGIPPREAEMMDPRQRLLLQESWRALEDAGYGKERIKNSTIG
MFVGVEDGDYHMLSNEKGSVTSNHNGVLAARLAYFLNLDGPNMAINTACSSGLVAAHQAY
QSLRNQECDTAIAAGINLLLTPGVLTAMSQAGMLSEDGKCYAFDKRANGMVPGEAIAVVV
LKRLSKAQADGDPIYAVIKGSGINYDGKTNGITVPSGVSQSKLLKSVYDRNKVNPEEIEY
IVTHGTGTKLGDPIEINALYDVFKGYTKKQSYCALTSVKTNFGHTMAASGLVSLISMVQA
LRYETIPASLHCEQENDYINWQESPFYVNKTNKIWSKDNGKQRSGSISAFGLSGTNVHMI
VQSYSEAENTASLEQMPYYLLAFSAKTKEALQEKIQDMIDVLQKKDAQEASLAELSYTLL
QGRQHFNHRCVVVVQGREDAIYALQQVNGKERLPNLFHGKVSREFTRQKAIEQYAQELLE
NSRSFRENKRKYQETLYALAEFYCQGYEINGDMFYGDRKPRRISLPTYPFARTHYWVPEI
DTKHADHITSQSVAEFIPSQNTEKVILEKGWQEKAIHLKAEIQTGIVVVLGTVNTMKIAS
ALFADTEDIQVIQVIQVIHGSNPILEGISTDFYSISAGESLYQQMKDKQGEQKLIGVIDI
TAYDEMYEQSAAVESGKITFLQRLIAQDRSQGYKLLQVTHQLHSFQLAETKMQGARLAGL
YRMLGSEYKQIQSMTMDSDYLIHKYQQLAQQIETEFWNIGDENLSECCYRKGKRNEPQLT
ISQSNDDIQEKLPISKKYEQQDVVLITGGTRGIGAVIAKHVVSQGVKNLVIMGREELPKP
NEWNQYLKNKEKPEVEEKLRRMQSFIDQGVKVNYFNTSLTDQDGINNMVHKVNQDLGPIT
GVFHCAGVINKNPAFIKKSIADMEAVCEPKMKGLVTLHKALENEPLAFFILFSSISSVVP
TLSAGASDYAMANNYMDYYAQYQIGQGKSYFKSIQWPAWGETGMTKGGLRTPAYMKTGLV
SITTADGLTFLDIIESTSQIVNLPCVVVPGEFMHNQLLKPTITVEKKEAGLPSRRTSTLK
QKTENTQGVQANLRASILKWLQKIFMDEFKFSMDQLHEDIPFDEYGVDSMMLAELAQKMQ
MSISEPLNPSLLLENSTLALLTDYFMDNHFEDLQEQFGSETSNTIHVSSKENSISMKAEP
LQIISIESKDDNRNVSDNQSTITNETLSLKEDIAVVGIACRFPGASTKEAYWELLNKGLS
AIEPVPKKRWSPKDERMDYGGWIDDIDLFDPKFFNIKELDAAIMDPQARILLEESLQAIY
DAGYEHKQLSGEKIGVYIGGRSHANTNVNAVLQAPNPILGIGQNYMATNISRFFNFKGPS
LVVDTACSSGITSLLFAADSLREKRINMALVGAVNLLLNSSVHDMFAARNILSKDGEFHI
FDKRSRGEVLGEGAGVVMLKRLSDAIKDGNHIYGVIKAVSVNNDGRTLGPGSPNINAQKE
VMREALVLSGKQPDDIGYIEANGGGTAVVDSVEIKALSEVYCLDNQELAACAIGSIKPNV
GHLLFASGMAGFIRCVLSVYHKQIPPFLSATEPFPHYNFNKSRVQFNRQTIQWDVAEGKK
RVAAQNSMPDGGTNCHVVIEEFVPENMSYHPIYRPKIAPTMIKKALSSVEKNLTEQKQQE
PKIVRNKWGEYSVSGK
>I9NV79|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pelosinus fermentans JBW45|TrEMBL
MESQLSSLYKQIKDKKISREDAIRQIQEHKAKQTQQHILPILENHALSKTNTATLIEGIQ
TVLLQRASELSRVTIEDIDLEAQWNENGLDQVMLAALADRLNQDYKLELLPSIFYTQLTI
QSFAEYLVNEHYDMLAGQIQAKELSHSITEKSKVMTEFEEELLKEKAIRYFKQQLSSVLK
LPVHRIDENAQMEKYGIDSIMVMQLTNELEKIFGSLPKTLFFEYESLHQITDYFLAAYRT
ELIKILNVEYGTAISAKSDSSAGAEKKNSLFRSPRKLRTPEFSEGSIRQKAAAGVDVAII
GVSGRYPGARNLQEYWRNLRDGKDCITEIPKDRWDHSLYFDEDKNKLGKTYGKWGGFLEG
VDQFDPLFFNISPREAQFIDPQERLFLQCVFETLEDAGYTRQDLGLKENFNVEGNVGVYV
GVMYEEYQLYGAQEQIQGRPIALSGNPSSVANRVSYFFNFHGPSMAIDTMCSSSLTAIHL
ACQSLQQGGCEIAIAGGVNVSIHPNKYLMLGQGKFISSKGRCESFGQGGDGYVPGEGVGA
VLLKPLTQAIADGDNIYGIIKATAINHGGKTNGYTVPNPNAQARVIGQAFAETGINPRMI
SYIEAHGTGTSLGDPIEIAGLSKFFKEHTKDKQFCAIGSAKSNIGHCESAAGIAGVTKVL
LQLKYRQLVPSLHSKTLNPNIDFNNTPFFVQQELAEWKRPLINIHGKTEEHPRIAGISSF
GAGGSNAHVVIEEYIPEDQNPVINLISQQHPAMIVLSAKNEERLLEKVRQLLLMIKEVRF
FDANLAEIAYTLQIGRETMDERLAIAVNSIKELEEKLGRFLERDEDIENLYRGQNKRNKE
ILAALGPDEDMAVMIDSWMRKGKYTKLLEVWVKGLIIDWKKLYGKARPRRISLPTYPFAK
ERYWVPEFETTAVNHILTHTGNALMLHPLLHQNTSDLTEQRFTSKFSGKETFFVNHVKGF
RVLPEAACLEMVREALQQAAGRLQEGQKILITNIRWMFPVAVDESLLEVHIGLIPENSSE
IIFEVYSQPGGREEETIIYSQGTAVFSDVSAENIELDLAAIQEQCRNHFNASQCYEALRN
AGFNYGPEYRGMEFVYVGRGQVLAKLVMPSCIAETQSQFMLHPSLLNAGMQATIGFILNS
EDRRLMLPVALQELEILGPCSPAMWAWLRYSEGSAADTLQKLDIDLCDTQGKVCIRMKGL
EMQGDTEESTSGDSVEELRQTPAASKKQEAFEMMTFEETWQEQALSNRGPVKIRTLVCFL
SNVENQNKAAEEIQTLDPQTRILFISQHPNHTASSHTIYPISRKDPSTYEQAFQSIREDY
GEIDGMLYLWTIEDATCIEDYSVIVYLLQSIAAVKLKAGRVLLGAQFETGLERCYLDSWV
GFERSLGLVLPNTQVAVTYQKSSGPDAKSTMEDWLTKLWSELQTEKLQSVFYQEGKRYVY
QIQETFLETGSSLLQAGGTYLITGGCGGLGFLFARHFAKTHAVNLILTGRSALDAKKQAK
IHELEALGSHALYLQADSCDVSSMRSALAQAKAKYGEIHGVIHAAGLAGSQSLFEKDLAG
FKKIIEPKIKGTLVLDEVLQEVALHFMCYFSSSSAILGDFGSCDYAIGNRFQMAYAHYRQ
EKQLEGKGYGKSLVINWPLWKDGGMGVGEEENSKLYLKSSGQRFLEAEEGTVMFDCILSQ
STIQQLVLVGQPSRIKRFLGLTHDDVSLSLLSLNSPSRGRRPEMKGLNLEQCVEWDLKEY
ISQLLKIPFNKLDKEENLADFGFDSISLTQLAALLRSHYGIEVTATLFFGYSTIEKLTQY
FVTDHHNIMDEFYKEEAVWQPMEQKRSTENKAVVGPKFQRIRFARRREDTEDIKQQGSIA
IVGMSGKFPMAEDVHELWGNIVEGRDCIAEIPKERWDWQKFYGDAAKEVNKTKIKWGGFI
TEIDEFDSLFFKISPKEAESMDPKQRMLMTFVWRAMEDAGITPKEMSKKSTGVFIAACPS
EYTDSVSMQNNSLALTSTTPTVLPARISYALDLQGPSEYCDTACSSTLVALHRAVQAIQN
NECEQAIVGAVNLLLSPLGFIGLDSLGYLSPEGKAKSFQSDANGYARSEGVGVLIIKPLR
QAIKDKDQIFAVVKGTGVSHGGKGMSLTAPNANGMKAAMIQAYQAAKIDPRTVSYIEAHG
IASLLGDGIEVDALKAGYQELVARQTLQHVKNQHVCHIGSLKPCIGNAEVASGMAALIKV
ISAMRNRIIPGIAGFTTLSDHISLEGSPFQIAAGNYEWSALKNIYGSSLPRRASINGYGF
SGINAHVVLEEYVPKQEHIPPEENLPYIVPLSAKNRARLDDYARNLLIFLKARDGAAADS
ALHLADVAYTLQVGREAMESRIAFIVKSIKELMEKLESFIDGTENAENYFSEDAKQGIAA
QLLGTDDDFEELLHKWVAKGKMKKIAEVWSKGLPIEWELFYPDSKPQRISLPTYPFTRER
YKLFLQQEKKSSTTIENVKTQSRSEDFVQGNPKDTLEYITRLVQDTLGLPSNVAIDPQSQ
LREYGMDSISGIQILDKIRQELGTQLDGRRFFSEFTLQSIIDQLKSVANQDKILLSPWEM
DKKLPMSFMLNLKKTSFTHNSLPENIFLTGATGLLGAFLCNEILQQTSANVYCLVRAESA
TLGLQRIQENLNKFALWQSDYQSRIIPVLGDITMSQLGIEKIIYTELSHSIDAIYHCAAL
PNHILNYYSLRNANVNGTLAIIEFAAAGKIKPIHFTSTIAVCSQMDGDIMLPTHQMETLL
GQGKNLTSGYAQSKWVSEHHLMQVQERGIPITIFRCGEITGSSQTGYGVTEDMVHNFLRI
FSKVNAIPEWNEGVMDIVPVDYVSKVILAVSRQQDCYGKIYHLNHMKPFPVREFFAYLKK
KNSRLSKISFEEWADRCLQYIIELPESSVKTVMVGSFTKLDSGSRVFKYYFTNMGLNNEN
LQTALQGFDVDFPKINDQWWEKCMNQILLFDR
>I9NLE0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pelosinus fermentans JBW45|TrEMBL
MNSQEILLALQAGKISHEDAKRALMKNIKTVSTSGGLRIKEVSSGVPEGEVGTVGSSEPI
GTLKLTPCWKEKVILQQATAPDYAQQIVVLCEPDEVTKEIIESKMTRVRFLTLQSEQTDI
EERFQTYAIEVFEEIQRILKEKPIGKVLVQIVVSTRDEQQLFFGLSGLLKTAQLENPKLI
GQLIGVDRWEDFEKMVGKLKENSQSPHENQIRYQEDKRLVSSWREVEASQKEANIPWKDQ
GIYLITGGAGGLGLIFAKDIAYKVKNASLILTGRSPLGEDKREKFKELEGLGVRIEYKQV
DVTQKQAVADLIHSVQKQYGSLDGIIHGAGVIRDNFIIKKTKDEFLKVLAPKVTGLVNLD
QASQDIGLDLFVLFSSIAGSLGNPGQVDYATANAFMDVYARYRNLLVTAKQRQGQTLSIN
WPLWKEGGMQIDEETEKLMMQSMGMIAMKTSNGIRALYQGLASDKDQMMVMEGDIKRLHT
VFLSQTTGVEVSNPSSTVEEKKTVPVLEPKLFKEKAINYFKEQLSSIINLPKYQIEADVQ
LEKYGIDSLMIMQLTNQLEKTFGSLPKTLFFEYQTIQELTEYFVGSHRDQLIELLGLERK
AESIESAKEYVTVAEPVQSNHSSRGRSRFASLNIKSQKESNTGHRDIAIIGLSGRYPGAA
NIQEFWRNLRDGKDCITEIPKERWDHSLYFNEDKNKPGKTYSKWGGFIEGVDQFDPLFFN
ISPREAEILDPQERLFLECVFETLEDAGYTRQSFSSRDFDLEGNVGVYVGVMYEEYQLYG
AQKQALGKMSALPGNPSSIANRVSYFCNFHGPSLAVDTMCSSSLTAIHLACQSLRQGECE
LAIAGGVNVSIHPNKYLLLGQGKFVSSKGRCESFGLGGDGYVPGEGVGAVLLKPLSKAIV
DGDNIYGIIKATAINHGGKTNGYTVPNPNAQASVIKRAFAKGGINPRKISYIEAHGTGTS
LGDPIEILGLNKAFQQFTQDKQFCAIGSAKSNIGHCESAAGIAGVTKVLLQLKYHQLVPS
LHSKTLNPNIDFSNTSFKVQQELEQWQRPVLEFNGESKEYPRMAGISAFGAGGSNAHVVI
EEYISPQLERPQIMNTNQNPAIILLSAKNEKQLYEQAKRLLTAIGDQQFSDASLAEIAYT
LQIGREAMEERLAVIVGSIKELEEKLRAFVDGQEENMEDLYRGQVKRNKEMLAIFKADEE
LLEAVDKWIERRKYAKLLNLWVKGLIFDWDKLYGEIKPHRLSLPTYPFAKERYWAPKQES
KFVSDTTVRQAAAIDHSSSYRNTSDISEQQFNLTSAQHLLQPITESNSSKRFDKQGGVLL
RTLSDQPTLPSNPAGQTRQLIALSSTSVSSLQPKNNEESKLVTHAQPGIPTELLQEELAT
SLAEALCMKRSDVDVDVSFIDMGLDSIIGVEWIQAVNKQYGTTIMATKVYDYPSIREFAG
FLDKELSIQSNPPKRIQAISGLDQSPKEFSLQSVELTSIESATDLRGSTSDQIENQGKSN
PLAVSFSVETLQEELATSLAEALYMKQSDVDVDANFIDMGLDSIIGVEWIQAVNKQYGIT
IMATKVYDYPNIREFAGFLEKELNNHHRGGLNQVSLQSISSPSLRELIQQVHQGNLDIEQ
ADKQLHQLYIKA
>A0A0N1GR62|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MIHEPERNRPGEAPSIVRMLRTHAVQRPDKTALILLSEGEEESDRLTYGELDRRARSLAV
RLQAADLAGEQVLLPMPTCLEYAVGMLGCLYARAVPVPIYPPGHRRHAERINGIVGDCRA
RLALTTAARTGSLRTRFDQIGITSVDCEIWAVDGPARETGDPPGGDGGPGADGWAEPELT
ADTLAYLQYTSGSTSDPRGVMISHGNLAHQFGLLAEGFDLGEHDVNVSWLPIFHDLGLVA
GLLHPLYLGATAVLMPPVAFVQRPERWLDAIVKYRGTTAWAPNFALELCCDRIDAAHRAR
LDLSSLRMVTIGAEPVRPDTLERFAETFGPCGFGPRTFTPGYGMAEATLALTNRSPREPL
TVSAFGADALSRGLLSPAADGERSRRLVGNGHTWLDTELLVVDPDTGLICPDNTEGELWV
RGATVASGYWNQPEETARTFGAHLADGRGPFLRTGDLGALADGEVYVTGRLKDLIIVRGR
NLHPQDIELTAARSHPGLAPERGAAFPVDSGGQERLVVVHEVARERRTDTDPQEIVAAVR
QAVTEEHDVELGAVVLLRSAALPITSSGKVRRRHCKQLYLNGELAAVHTWEAPTAPVTTT
AAPAAGMPVAAAASGSYESITQWLVTRIAERGRLTAEHVGVDTPFSAFGLDSLTLVGISG
ELGEALGRPVQPTLLYEHPTVARLARALSDGVQAPPVRRSGPPGEPIAVVGMACRFPGAE
SVDAYWDLILAGRDAITEVPADRWPADAYYRSGPPVPGRTTTRWGGFIDRGYDFDAGFFG
ISAQEARSMDPQQRLLLTLAWRALEDAGIPAESIADGDTGVFVGISGNDYARLQIRDHAG
LDAHSGTGNALSVAANRISYFFDLHGPSVAVDTACSSSLVALHQAVTSLRQGECELAVVA
GVNLLLSPDLTVVFSQADMMAPDGRCKVFDARADGYVRGEGCGVVILKRHEDARRAGDRV
HAVVHGSAVNQDGRSNSLTAPNGLAQEAVIRQALAAAGMAPGRIGCVEAHGTGTSLGDPV
EVAALQRVYGEPGPGTGPVWIGSAKACIGHLEAAAGIAGLIKAVLMLRHRTVPRQPHFQE
LNPYIALAGSRCRIPERTEEWPTGRQPRAVGVSSFGFGGTNAHVILTEAEEAARPTALSG
PDQQAADADRWELLPVSAKGGAALRRLAQDHADLLEAPLGTPFPALCAAAGARRTHHDHR
VAVVARSAPEAAVLLRRHARGEEHASVFAGLSDARRSRPVAFLFTGQGSQYPGMAGPLYA
RHTAFRRALDRCDRFLTGEFGIGLLPTLCGSVGERVDLAQTRYAQPALFAVEYAMAELWH
ACGVRPDYVLGHSVGEYVAACVAGVLSPEDALLLLNHRGKLMQEYSPTGAMYAVHAPAPL
LAELCAELHAAADDTVCVAAVNGAEDITLSGDPTTVTELTRSWADRGARVSRLGVDRAFH
SPLMRTVAERFAPHARSVSCRPPTIGLVCDLSGELAGDAFADPGYWTRQLLEPVLFGPGL
ETLKAQGCQVFLEVGPHPALTAIGAASHPDARWLATLHRDDTDDRRFLSSLAEHYVHGGR
VDWTGAARERTGEAGRPPAPVPLPGHPLTETELRYVPEQSTAPGEHPLLGTEVELAAAPG
RWFAHTLRADRPGFLAQHRVLGGPVLPAAAMLEWALAAARASSAEPAAAWTLGQVTFNEP
LRLAENEPVAVQATADGDGRVRCYARGGRKPGQPWTEHVTVTTAEPAQAQPTAPGDTAAD
ASSDAEHMTALDVDDLYQRFAALGLDYGPDFRALKELRSNGDEALGLVEAELSGEDGYVL
HPVVLDACFHAVGAFLPGTAAQDGLWLPAALDRITVYDRLPSRVRCHVRRHGSGAPGDLV
VDLALRSDQGTLLADLEGLRLRQVAADRHGDADGVPAVPAVSTAPPPRRYDLVWQPFPDP
AGQDGARTRRRTDGTWLVLSPDPAAVRDWPAALGRPAVGVLTASAAGPPAGPGAEHLLDG
LSERPGRIDGVVLHYGAAAAPGTDPAQRAYDLARHALPLLQQVLRGLALEGMTVVITSVG
ACRPVSDTQPPDPAQSVLTGLTAAIAAEYPEVTCVQVDTDPNAPATPAALLERVDAMPGS
GHLAQRGDDWYRARVREGELPERPAEPGRSVLRPDGAYLVTGGWGGLGQVTASWLAARGA
RTLLLVGRTVPVCVPPSVTALRNRGVRVELLAADVAEESGALRIAQALDELPPLRGIVHA
AGVSEDAAFSRLDWGAFARVMDAKVRGAWRLHRLAGDRQLDLFVLFSSMAALTGSAGQAN
YTVANAFLDSLAQYRRHLGLPAVSVAWGPWADAGMAADHGLLPLLARQGVHALRTDTALD
ALDRLLATAPPQVGVARLDWPLFTARSAGHPPYPSLDRPAPDTTPDRTTDADDAGLSAER
LAITVLEDPEAARKAVLAGLLHRVTVLLALDSRQRDELRPSFSRMRLNELGIDSLMAVRL
RNRLLSELSTDVPPHFLLGGNTVGDVAELICRQLMLRSLVTDGTEPLTGETEVLTL
>A0A0N0N042|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MVHTPRAELIRPLAELLTEQAARLGEKVAFRDATRSVSYADLERRTRRLAGHLAGHGVRR
GDRVVISLGNRVETLEAYYAVNRAGAVGVPVDPRATGKELAHFLDDSGATAVLTDRAHTD
QVLDLAADRPRLATLVIVDAARSHAGPASVPLLNFEDLATTDPATPARDDLGLDETAWIL
YTSGTTGRPKGVLSTQANCLWSVAHSYTSVLGLSERDDVLWPMPLFHSLAHVLCVHGVVA
TGATARIMPGFAAEDVLDLFARERFTFLVGVPTMFHHLVRAAAENGFAAPALRACLVTGA
VATPSLKESFEAAFAVPLVDSYGSTETCGAITMNRPGDPLVAGSCGLPVPGLGVRVVDPE
TGADVPTGEQGEVWVNGPNVMRGYHDQPEATDRALRDGWYRTGDLARRDGQGYLTISGRI
KELIIRGGENIHPGEIEDVVRGLPGVADVAVAARPHEVLGEVPAVYVVPTASTASTASTA
QDGWDAAAVFAACRDQLAHYKVPEELYEVEAVPRTASGKVTRHALATRPARLAATRAARN
EWLFRLDWTPWTGPEGPEGADADPVPVESVFQVPGLAAVPPGAEVVLLPYTPRGQDVQDV
ITDTGELVRAWLADERFAAARLVLVTRGPVVAPPGTNPVHTAAWGVLRTAMAEHPGRFGM
ADTDEHEDSAAALRTAVAAGERELAVRAGRVFVPRLTRAVPAADLVLPPHRFDGTVLVTG
AVDGLGGTVVRHLVAKHGARRLLLAAGTGGMSDTDAVEGAAGLESEIAELGARLTVTPCD
PADRVALTALLAGRPDPVTAVVHTSADPVALWHLHELTRDVPRDGAAPVTAFLSFSTTGG
SLGAPGAPEQAAHAAYLDAVVRHRRAEGHPATSFAWGPWAAAPAVPEAERTWLKGLGVGE
LTVAEGLALLDAALALDADVLVPAALGTTGLRGHDDHTAPAALHALIPARSPQHAALDTD
ARPADAERRPDAADQLPEADPRTLALRRRLAALPSVRSRRLLLDLVRTEVASVLGHASTA
AVAAERAFKDLGFSSATSIALRNRLTEVTGLTLPVTVAFDHPSPAALADRLHDELHELHE
VHDLHEPASTVVAPRTTGTGEPIAIVGIGCRYPGGVHSPEDLWRLVSSGADAVSDFPTDR
GWDLSALFAPDPDRPGTSHTRNGGFLHDAGDFDAGFFGISPREALAMDPQQRLLLETTWE
AFERAGIDPVTLKGDPVGVFAGMMFHDYATQLGREPEGLEGYLGTGNAGSVVSGRISYAF
GFEGPAVTVDTACSSSLVALHLAAQSLRQGECSLALAGGVAVMATPSVFVEFSRQNALAR
DGRCKPFAAGADGTGWSEGVGVLVLERLSDARRNGHEILAVVRGSAVNQDGASNGLTAPS
GPSQERVIRQALVNAGVSAAEVDVVEAHGTGTRLGDPIEAQALLATYGQGRSGDRPLWLG
SLKSNIGHAQAAAGVAGVIKMVMAIRHGVLPRTLHVDEPTPHVDWSTGAVSLLTEERAWE
VDGRPRRAGVSSFGVSGTNAHVIVEQAPDLDPVVEEPSVQWPVPVVAL
>A0A0N1G2U1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MVSLAALWRAAGGGPAVGGGHSQGEIAAAVVAGGLSLEDGARVVALRSKAIRAIAGRGGM
VSIALPLAAVEDLLSGWAGRVDIAAVNGPASVVVAGDADALDELMAHCEAEEVRARRIPV
DYASHTWHVEAIEGELAEVLADVAPRSGSVPFFSTTEAELVDTATLDGGYWYRNLRQRVR
FAEAIERLAGQGYAAFVEASSHPVLGMAVQEAAPDAVVVGSLRRDQGGPDRFLTSLAEAW
VRGIPVDWTAV
>A0A6C0QDH6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. S4.7|TrEMBL
MEAPATPAPSTAELADWLTRTVADYVSSEPSEIEPDVPLSEYGLDSVSATTVCANIEDHL
GLVVEMTLIWDHPTVAELSQALADELESARG
>A0A073CGT7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Planktothrix agardhii NIVA-CYA 126/8|TrEMBL
MQVLNASMNGTKPQQPSVTVHHPESLVKGIESFESVATIEGWLVSQLAERLELEALEIDL
EEDFTNYGLNSIEAINLSGDLETILGRRLPPTLLWDYPNICTLAKYLADHNTLDITQYQN
GISPKDAEHLLQHLDQLSDTDVDTLLNILLSEQEEIND
>A0A448DAU0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Neisseria canis|TrEMBL
MSYLAGMSMQCAQGESSSVLAGLAAPGQPEKTAFNFLNQPQQAAYFRAFDCERLDEGALF
GLLEHYLLEAAEDAGWSAQALSETPVFIGSTSYLLPYYELHYLAKQQLFKQHSLHQLADY
LKQSRGNRQVYCFATACTSSGQALMQAHAMLESGLISRAFVVGLETFNLLTLMHFHSLGL
LSDRCVPFGGDGFVLGEGIACLALSREKTDGGKQFRLASAAANTGTASPVETDSESLCRV
MRQALGQAGVAADDVRMVKAHAVGTAATDEAEAAALQSVFGRTMPLAAFKPLIGHTQGAS
TALETVLLYQALRQGRLAGEAALQGSYPLDAGFYLANFFGFGGSNMAFVWEWQQ
>A0A1V2R9V5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MLFSSISATWGSNDHGAYAAGNSFLDALAEERRARGLPATSIAWGVWDTRDWDEVDAVLD
QGAGRVTPSRLRRQGMHFLNVDRALTALGEVLNDDETFIAVADVEWRKFAPVFSVARPRP
LLETIPEAREETDPAGSAESQAAERGEYASRLAGMPVAERRRTVIELVRSHAATVLGYES
IAEMPAERAFRDVGFDSLTAVELRNRLGAAAGVRLPATVVFDHPNPTAMADYLLAELVGH
SAVLDEFDRLAAGLTPSDDAERAEIVARLEALTQRFRALQPEAAADEAEQRQLQGATAEE
MFALLEDELDDPDFD
>A0A425I2V7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii CAST|TrEMBL
MPTVSAAGGQQVSWYSSRVRLDVLDALRDHVILGMPLMPGAAFIDALLAAGRLEHTRIDR
RISSSAVIKLSDVSIFSPLLLPESLGSGVAPGEQGFHPSSLELSVEMKPDGRDHLAEVRS
RRIGTTLAAANEEEYEQSHCRGRLAISAGTSQLPASTGGQLTDLQRRFYSEAAVDVSQLY
ATFAELGWQYGKLFRPIAQLFKTDTEAFAELRLPRPVLPCEEGFIIHPAILDGLFQVAGS
LLLTAEKAPAGSVYVPIGVDELAFIPSTSKRDIVWGRVTFAEADDEAKRRQERVVNCTLY
DEGGRVLLYVSGLRSRLLRTEVLLSGTGAAAESNKLWSVEWRASHQQPVAHHEEPVDHST
NWLIAGVHPAVQSQLEEFFLKTMPGAKVVFCAPSVVATDVRRLLQQEAWNGIIHIGGVTA
SISEMECLSDVLVLLQAVIDWQANESSPRPLPAMFLVTRGACCEATENSGLSHSLAPVHS
GMRGLFRTAKAELEALWNRFVPLHYINIEPSSDKQTVTPEELRQVFSVIQQQGAKAQFIQ
DQLTQEPSKPLFYESESLLRDGELLLPRLVPASLEDCGDGNALAEAMTGTIVITGGLGGI
GLVLAKWLTGQEARAVVLVSRTGTPSAEVQRSEDWHLLQSRRQHQTRIVTASCDVGDREQ
VKLLFRSLRAGSFVCHSTGQVVELPPIRGIFHAAGVLRDCPIQKQDAETLASVFRPKSQG
AWNIHNALEELNMNEGLKVFLMFSSIASLVGNPGQANYAAANSSLDALASYRRCRGLAGH
SIQWGPWIEQGMAAELGERLERAGFRGISNKVGVEVTEAVVSQGTTGDFVVACQEFIWPR
FVMRYRGCLPAIFEEQTRSVTVRMRDERSSRQAAGPEMHQESAFASMAPDELRALIQATV
SGAAKQVLGTAEEPPADAPLQALGIDSLGAVEFRNAVQDAFDIRLSATLLFDYPSVQAVS
DHLWSMVRAKTAIDTSSRGDDQLASATVLQDAGVSIAVVGMACRLPGSVNDLEAFEEMLL
TFQDCIQEIPPSRFSIEEVYDPDPDAKGKIYVREGGFIDGAELFDNRFFGISDAEAREMD
PRQRISLEVSYEALVDAGYSREDLLGSPIGVFVGAMNHDKLYDDLRQLTSYSGTSTALAI
LANRLSYSFGLVGPSVTIDTACSSSLVAAEYATLCVACGRSRQAVVHGINVIPKVEG
>E0I748|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Paenibacillus curdlanolyticus YK9|TrEMBL
MQAIQKYILEQVATNRLERDRASALLKELTQHEPANTNETKQDIAVVGVACRFPNADNAR
DFWTNMMQGDDAIETFPTNRIDDIRYLNEQSFAMLRGAKFKLGGYLKQVDLFDPDFFQIT
PAEAKAMDPNQRLFLETAWEALESAGASKEKLSGSLTGVYVGYSYEEGYKKLLEEFDGHA
VLGNMPAVIPARLSYLLNLKGPSMIFDTTCSSSLVALHHACQAIRAGDCRQAVVGGVQTL
LLPLDVDGAEMGTESADGKCRSFDADASGTNVAEGVGVIVIKPLEDAITDNDHIYCVIKG
SAINSDGASNGLTAPNPESQAEVIKRSWKNAGISPTRISYIEAHGTGTKLGDPIEIDGLK
RAFRSYTDDKQFCAIGSVKTNIGHLDAAAGIAGVIKTALALYYKKIPASLHFETPNPLID
FSDSPVYVNKELQEWKTDDGPRLAGVSAFGLSGTNCHVVLEEYTGSAVSEQSELAQQVFT
ISAKTKRALFQSVEKTKQFLQQNDSWRLVDLCYSMSRRDSYSHRIAIKAKDTDELKAKLT
RVAAFGSYEMVSDEMREWGIGYACTSMETRIQRLESTSVEDIFSGYLNGWQIDWNRVYAN
TRCQVVPLPAYGFDQKRFWPKLGLKEQRYEEIDASPYLFDAAWMPKELQNGLTATEETKF
WLIFSEESDLENELLKELKLRKEDYIIVRPSQHFSRQSLQEFTIHPAHTSDYDLLVSALG
ANVWESLTGLIHMWNCSNDDDSMHDLKTLEESQYKSAYSLFYLMKSLQKHRISPKLQMNI
ATSYAFKANGSEPTIYPVRATLAGLAKVISQEMPKIVTYCIDLDTKQMSGHQAAQAILTE
VSQPKGERDELVAIRKDGGRLVQVLARHNPAPVADRKRALKENGVYLIIGAGYLGMEIGK
YMAEKHNVNLAFITRTALPARDAWESLIKNGDENSRVYSQVKGILDIEKSGSKTIHLSAD
ATSFSEMEQAVRQVKETFGKIDGVVFSIKQIYGKMIEEMDENEFHGAVMSKLKGAWIIDE
LTKDADLDFFITLSSISSIMGGPKNCDCTAVNMFLDAFGDYRLQQGRATTTINLTEIVTG
DKHGYLLDVTMLPPIQYSQFIACFDRVLSKAYDLIVVSDFDLKIMKELLGVVKINFSDAL
RAEILAHGSSIESEKATAVLSGLSMEEVVGKITEMWKEVLGYDDMPENASFFEVGGTSLS
AVKLLRLLRDAFQVQVEIADLYSYSTIRELAGYVKERDVQQADDMMDILNEFESGSMTLE
DAAKLLGKV
>Q311J0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Oleidesulfovibrio alaskensis (strain ATCC BAA-1058 / DSM 17464 / G20)|TrEMBL
MNFDPESTTGSAPAVSLSENALKKLLSLYINSIFPHKEPIEESMAFARYGLASADLLNMT
AAISKQTGMRLPSTLAFDYPNIQLMARALYRRQQPQERTTEPVAATLREIQQSPGLPRNI
ADTDIAVIGIGCRFPGGADSPEKYWELLSNRADAISEIPAERWDIEQFYDPRQGVAGKMN
TRFGGFIDDIYGFDAEFFGISPREAKAMDPQQRLVMEVAVQALGSAGLNWQKLAGTATGV
FVGVSGSDYGRQALVSADSISLYSGTGSASSIVANRLSYFMGLRGPSMAVDTACSSSLVA
VHLACRSIINNECAIAIAGGVNAILTPEMHIMFSQAGLMAPDGRCKTFDASADGYVRSEG
CGIVILKSFTKAVEDGDHIWGIIKGSAVNQDGFSSGLTVPNGSSQEELLRQALKNARCLP
DAIDYIELHGTGTAVGDPIEFSALLSVFGSDSARRTPLALGSVKSNIGHLEQAAGIAGFI
KVLLCMKHGILAPNLHFTRPNPHIPLADMPAAVVTESTSLDTFQQPFTAGISGFSFGGTN
AHIIVESYLFDDNENQTHTKRDPKAPHIVFFSGSSHNTLMQHAEAMAAYIRTADHATLGS
ISYTSAAGRNHLSHRAAIISTDKQGLTNSLASLLRNEPDNMTFTGVRTAGHLPAGMAFTG
QGAQYFGMGRSLYATEPVFRNSLRRCAEALAPHMPAPLIPLMLEDTFSAERINETIFAQP
ALFALEYALGELWRHWGFSPTLVLGHSIGEFAAAYFAGVFSLDDAAMLVATRGRLMQALP
SSGGMLVVFATAEALKEILQQYTTLTIAAENTPSNTVVSGSREELSRLEDHLTDSAIPFT
PLAVSHAFHSPLMQPMLDDFMKAADKVSFSQPEIPFLSTVTGTLLTHEIACPEYWARHIT
SPVMFRTAMRKLRHSGTEAIIEAGPGAVLCGMSAESGLLWAPTLQRGINDRERISETLAA
MFAAGIALDWERVFGTAKQRKIHLPSYFFDHTYYRHDVPSSAACSLPADRRIQQHIAGRK
KEAQAERNEKQQTHDALSDVVRAVLQWPQDNPLPENRSFLRLGIDSLMAMQLRSHLLKEY
AAEMTLSEILAAPSLEWLRSQIGSGGQSTSGSGTTAALRHDPANRFAEFPLTEVQKAYWM
GQNPDMPLGGTSCHVYAEVDVNNLDIARFESAIRLLIKRHDMLRARIQKDGTQRVLPEVP
PFTLRIDSPSSEQELDDLLRHKRHKLSQGLPQEADGALFFLSATKKDTDGLRIHVVFDML
AGDGHSFMILLDELEQLYAGNTPPAPMPEITFRDYVAYSRSSAETKNSAAAQEYWNRRLP
ELPAGPELPLVADPAAISYPRFVRHKGKLSAGAWQTLCDKASSYGLTPSATLLAAFSRVL
GVWSSTKHFCLNLTLFNRPEEMPDLRNVVGDFTTLLLLETHNAQALPFIRHADAVQRRLM
TDLEHRKVSTLNLIHELRKQHDGKALLTPVVFTSLLPLTRSGGRRGFSPRGADARVEFCI
SQTPQVYLDHQVYEEKGELRFNWDIVDGIFPQGMIESMLQAYINLLETLAATTQAWEQVF
SAEALLPPLFMQRIRELNTPQDGHSDDTLLSLFEKTVAGTPDAVAVQTTQLTLTYAQLSG
YADAIASILHRNGVAAGAPVAVIMKKGWEQIAAVLGIVRAGAAFLPVNTSQPSSRLAAIL
QQAQAQMALVQKDYNAPADWPQHIDRIEVSAGLCKAGGSGPFVPPAPSDLAYVIFTSGST
GTPKGVMQDHASVVNTITAVNSGYGITSEDVVFGVSNLDFDLAVYDIFGTFAAGGTLVLP
DAEQRKEPAHWLELIERFGISVWNSTPPLMQMLTTYAEAAPRSLPQINTVMLSGDWIPVP
LPAAIHALFPLARIFSMGGATEAAIWSVKYDTAQLPQGSRTVPYGTPLPNQKLMVLDEQL
EIAPAWVTGELHIGGKGLALGYLNDPEKTAAQFIRHPRTGERLYKTGDLGRYLPDGTIEF
IGRKDAQVKIRGHRVEPGEIEHCLLRHPAVHKAAVIAVGDAGKPRSLAAFVVTTAHDELR
AFLRSNLPEHMVPSQIIAVPALPLTENGKLDRKALQRMIPAREDRNAATAGPEQQLLGSI
WAAVLGQQTDIDTSFFEAGGDSLLATRVMADIRRQAGIEISLNTLFMHPTIRELAHVIAE
KRAEKEQGPDEQRMLTADSENRYEPFPLTAVQHAYWLGRNASFELGNVAAHFYYEIDATG
LDIARLSSAWNMVISRHDMLRTIIHDNGTQQVLQTTGAYSFPATDLRKSDSQTIDRHLEK
IRQEMSCQMLDTSRWPLFDIRITMMPEDRFRLHIDIDNTIADAWSLFTVLREWADLYADP
EKNLPLAAIGFRDIVLASQAITDTQARNADKQYWLERLKTLPLAPELPLAADPSSIEKPV
FSRLSDRLAPARWKKLQQQAQKHNVTPSALLMCAFGTVLRRWSKEDAFSINVTLFNRPSV
HPDIEKVVGDFTSLTLLEMPDTRENFARTAQALQQQLWTDMDHSRFDGVEVMRHLAQQHN
LGGKAVMPVVFTSALMGSAGQDASVLTSLGDMVYSIFQTPQVWLDHQVYEHHGELVLNWD
SIDGLFPAGVMQDMFTSYIGLLNSLADRQENWGSAELALPPEQIRRRKHMNDTTEKVLPV
TLHALFEKSAQKHGQRPAIKAHDRTLTYAELDRESAAVAALLKARGTGPGDIIAVCMEKG
WRQSVAILGTIRAGAAYLPIAMPHPAKRLEAILCDAGVKAVLTRQELQATAGFEAAPVLC
LEEADIFSGENAPPAAELSAAATAYVIYTSGSTGLPKGVVCSHQAAANTILDINARFDVS
ETDTVLGISGAGFDLSVYDMFGAWAAGAAVALPDQACGNDPAAWYECIIRTTATIWNSAP
ALMQMLLSHVTGTAKAFPASVRLTLLSGDWISRRMAADLRSTAPDMTLVSLGGATEAAIW
SVLHVIKDVDFSLHAIPYGTPMTNQQMHVLNAALEPCPEWVPGQLYIGGSGLAEGYLNDR
HKTQAAFITHPATGERLYKTGDLARVRPEGFIEFLGREDQQVKIRGHRVELGEIENALTL
HPQIKEALITLHGESISGKRLLAYLTVQQQPPAAEELRDHLAQVLPRFMIPDHFFFLTEF
PVTANGKIDHKALPLPSEEQATHAVQTGGSDLVQALQGYLAAALESQAVLPDANFFDMGV
SSFHLVQVQNDIRNHLGKEVQIMDFFMYPTITEFAAFLEQDISAVHTEQSASAAAASEKS
PRRRQGKRRNTR
>Q311J1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Oleidesulfovibrio alaskensis (strain ATCC BAA-1058 / DSM 17464 / G20)|TrEMBL
MSSEYIAERIAVIGMSCRFPGASSPDAFWHNILLGTESRSEFTGSDLLDAGITEKSLKDK
NYISSGCIIDDSDVETFDPAYFAISHTEAEVMDPQQRLFLKCAVEAMENAGYHGRDGLRT
GVYAGSRTSTYIHGFCGNPYLQSGTGEGFQILVGNDKDYLANRVAYKLNLKGPAVVVQSA
CSTSLLAIHLACEALRSGECDMALAGGVALMIPQRMGFEHQEGMILSPQGHCRPFCADAD
GTVFGNGAGIVVLKRLEDALRDSDHIEAVIAGSAANNDGAAKAGYTVPSHEGQTRVIEDA
LAYSGVEAASIGLIEAHGTGTPLGDPIEIAALSSVYADRTTRKEFCAVSSIKANIGHLDA
AAGVASFIKAVLCVKHARIPPAANFTTLNPRIKLDGSPFYIPRRAAQWNRTATPRRAGIS
SFGIGGTNVHMYIEEPPLQPAMPDTGSNPVLLTVSGNDAAALQRNLTRWADYVVQEHTTQ
DWRLADACYTAATGRKHCRYRYTVTACTAQEMHTHLRNAAQNSMFRQTGGGLKTAFAFTG
QGAQYTGMGQKAYSTYPVFKEALDTCADILADTLDYPLPEILFNPACKDLLCQTRYAQPT
LFALEYALATLLRSWGITPAAVIGHSVGEYVAAVVGGIFSLQDGLAIIAKRGELLQNLAG
GTGMTAVRLQEDQLEKLIKKMGLPLDIAAVNADSGTVVAGTSEALARLHAELGRQNTAHT
PLKVSHAFHSRHTEPAMDPFATFLQGFSISPPAMDFISNLTGKKENSAVQSPEYWASHIR
NTVRFKDGVRCLQECGITTVIEIGPAEVLSTLAQFNADATEETPRNRQMPLWIPSLRRGI
DDEQSLLDMLGRIYQQGHNPDWHAVFAHRPHRRIPAPVYSFSTERFWRGKTHARIRHTLL
RGLSSSQKPDSSIRDIDIRRWSAASEELAALYCRKALHELDQQAHPPASGYSELITSLRK
HLSEKHADMLPAGDITIGHLEQKERQLAEEFPQAHVLLAFLKQRGRTLKDVLSGRCRPEQ
AVLEMGDTAEFMQQLHATPFFRFYNEQLQNAVSTIIADTSHGSKAIRILEAGALTGGASA
YLARTLKENIAFSIAEASAHAGALAKRNMPQQTRVLVADIFSSPCPQQHGLYDIIIAANQ
LHGTPDAELALRNAASYLLQGGILLFRETYRPTLVTLMAFGPLLPVRKDTVLRPRSAYLS
DGQWIELCTRCGFSHAVKLFAGHEENSILGEITLAAQRAENNPGGTWAFENDLSGSAART
DSITEKNSGQPYGVYTAEWIHAGKTDSAGSTAGGTWSVYPHPSASPFAESIIAQLRAAGA
PFSIRFDEADTPLPPDNILFIPAERTSADSSEADTAGHETGRFIALLQRHSKTARRILLL
CPAGTDAMPTPTGAALQALAETAAAEHPGIEISVRHCSAATCARQLQAVLTENMREPVVI
TETGELRVRRIRRTQLPHGQPGIQIGTAATCLITGGLGGLGLQLAGWLIQRGARSVVLAG
RNAPSPEADEKIRAWVRQGVHISTAAADITTEAGWSRIETVLREHPEVTYVFHAAGIASQ
KPVNTLEQHELQATLAAKTSGTERVLAFCGRHNAHAVLFSSIATMWTTSGFGAYAAANAF
MDALAMRQKVTVLNWGGFSDAGMIAGSKTLLDGQRSMGLFPLVCARAFDTLDLVLANDIH
HAAVIDADWKKFFASLQTVPAVFTELHPCGAESSPAEKTQHNSGIQEQGYDITTMSHAQR
IAAISGWLHNNISATLRIAPEKLTSDTDLLTVGLDSLLFLSLSQQLEKELGLKLSPGRIF
EMPTIAELAEFLAGVEDEAEGQKNTRAEIQTTGSTCAITPQPHLRHEPFPLTDIQHAYWI
GRTGAFELGGIACQSYAEFNAADLDPVRYEEAWNRLIARHDMLRAVFMPDGNQKILAEVP
RLTIPVKELADLPAAEQQKQLLAMRESLSSMTLDPESWPLFHVEISHTGQGRYRIHMILD
LLIVDVFSGMLLIRELQHLYDAPDTALPPLELSFRDYVMAEMAYRKSTRWQQAQDYWMQR
LDTLPPAPDLPLARQISDIERPRFFRRQYRLGKERWSAIKGAAAAKGITPSSVLLAGYAE
VLAQWSASARFTLNVTLFNRKQFHKQINEIIGDFTSTTLLEIDITRQSGFAERAESLQKQ
LWKDLEHRDFSGVRLLRELARKGSLRLGAAMPVVFTANITSQSTQEKAVLDTLHFQSTQT
PQVWLDNQVYEEEGNLLVYWDVVDDLFPDGMVDDMFTAYCSIIDTLASESCKSAWDAPVP
QLTPGAQLAVRNRRNYPVHPCCHDLLHTALEVQAAAAPRKTAIICQNRHISYAQLWRQAA
ALRNQLADAGIRSGTPVPVLLPKSWQQIAAVLGILQAGGAYVPLDVEYPDGRIRHLISEL
KTGVVVTDAANSARIEKSAGRTILIMEHLEPVADQPEVSASRSTPDDLAYIIYTSGSTGT
PKGVMTSHKGAVNTVRDINRRLAVTAKDNVAGLANLNFDLSVYDIFGVLGCGGSLVLPDI
RHMKNPASWIDMIEQERITLWNSVPTLMQMLLEYLPNGLEGRLQTLRCIMLSGDWIPIQL
AKEIKSRLPLAALFSLGGATEASIWSVIHAVEQIPPHWNSVPYGRAMDNQTVQVLDHLLR
ERPDNVTGGIYLGGTGLAEGYWNAPEKTERSFITHPADGRRLYRTGDLGRYLPDGSIEIL
GREDFQLKISGYRIEPGEIEAQLNSHPAVSQSIVSAITDNSGKKVLCAHWTGKKDTSPEE
LALFISETLPHYMVPKIFVHVTAFPLNANGKVDRSALHVPQEHYAVPERTATFSAAEQLV
AQAMTEVLAVQPAGPEADFFDMGGDSLLAIRLINSLKKKTGISVSVPEFFQDSTIKAVAE
KIAAHGNTGTGSRAETCLTAPAGQQNGPSVYLVHEGSGTHMRLRELHMQLSRRCKVTGII
LPQHLPAGVSARKPDTLANYYADAIAASGEKGPCLVAGYCIGGFLAPLISRRLQYHGIAT
FQPVVIDPLPAKPLLTRDPVALLYWAASYFKIPPETLGLNFITLDVLEQIQNNTLEKNHP
AGSIYHALTGLSQQEAAAKLFSSLNGNADSFDNATMEQFSLWVNNIMNLQMGTADIRYVP
PLKGITVIEAQLPESYSGAEFENIRDFWTKWSEGPDSVTVIPRSEDHFDIIGQSGSAFIA
DTIKSIMEQQLYAG
>A0A1X6Y9H1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudooceanicola marinus|TrEMBL
MIRFAGRACRLPMAPDVTAFEALLYDGRSAVTQIPEDRWRHAPFFHPVPGTPGRCYSFAA
GVVDGIHAFDPAPFGISPREAAYMDPQQRLFLQVVWDALEDACLKPSELAGKEIGVFAGA
SLMDYGAGLGYDPQAADSYAMSGSSLAVIANRVSHVFDWHGPSMTIDTACSSSLFALNAA
RKALESGEVEIAVVGATNALLLPSQFVGFAAARMLSPSGLCQAFGAGADGYVRGEGAVAF
VLVRDSAEAPLSPRDRGRLLHVETNTSGQTVNIALPSARAQTALLRSAYDRAGIDPDQLD
FVEAHGTGTAAGDPVEAEALGLALGQRRGAPLPIGSVKTNIGHLEPAAGSAGLLKALIAL
ERAELPPSLNAAELNPAIPFDRLNLDLVQQRRPLDGAAMAGVSSFGFGGANAHAILGAPD
PRPVPAVEEQGPEPRPIHLASAFCREALREMLEEQGARLFDPAGQQNTRLVDEALHHRDL
HPHRVAIIARTPRTAQAARAAFEVGQRHPALEMAGSRLVDAPPVFVFSGNGAQYPGMSRA
AYAGSPDYRDAYDRIDRAWQAQAGWSLVDRLGAEDLGVQLSKAPVSQPLLFADQAATALA
LMARGAQPAAVMGHSAGEVAAAFIADALDLASAVRLVQARSLTQESLAGQGTMAALQLGI
EEARDILATHGDPRIEIAADNSPRSVSLVGPRDALEAFTRHARRGLRLACVPLRVDYPFH
SSAQEALRASLFDHLGVLDPGPEAVPIYSSVTGRRLVGGDLDSFHWWRNMRQPVLFRRAV
QALAEDGHRLFLEIGPDPVLAAYLRDSLGTEAGEIAVLPSLARKDEASPDPLDRVLARLL
VNGARLDRTALAPPPAGPSRELRSYPWQLKHLAASDTPALSRDSGRSGFHPLLGRQADAS
ATLWTNEMDPDLQPAFAAHRVADRCLLPGTALAEMALAAAQRSLGAEAVTLDDFDMTAAL
PLTPRSLTEVRTEVVPAERRLRIASRPRWSEEAWRGHATGRFARSVDPQSVPPVPAPDPA
LRPGDGPAHRLYAQAAEIGLTYGPAFRNLSHYRMPGEDEIEVILQARRPDGYDPADYALD
PVGADAVLHGLIGALHQGRFADEVLAFVPTRITRLDLLHPGCALAAGRIHLRRRGDRSLR
ADLTLFDAAGRLVARMDGVELRALRATQLVDLSRHAFGLETVPIDPPGLPQKAPAPWPAP
EEVVAQLGALSGEAPEAPEEAALLLDALAQRIAFDTLAAVGPASGGDAQGVAAKTLRQGL
SDLLAPLDLPTQALGQEAELECDLPDAAALITGISAEYPALIAECTALAHLAEALPRWLA
TGLPESEEAGFGRAVLDGLEVGSVMTEARARLVAENLGRLLAARSGRARRPLCVVELCDG
PPRLLPHLQGGADGAAWTAWALEEDRAALLPPALGDGIGRVGPAHLAEIGSVDLVLGCGS
AMTPVTWSTRLAALSPALRPGGAVILAEARPRPHLALLRLLGEALAEEDADRPRPPKLQE
APGLEEAARAAGFEETWAQPCAGACGLTLLIARTPDGVTRDGGAPRDTDAQRGEGTGLEE
MLRAALVGEALPSEETAEPLPVLTGAEGAGPLVLFAPKPEPEGQERPGAPRLAARLLALS
TRLRREEARGARDIWLICPGGAGAGGLAPPDPDQAALWAVMRTAKNEYPGFDIHAVDPTG
LPPGEAAARIAALIAAGTPETELCLMPDGPRALRVRAGAAPTAATSPAVRLTADPAGGLD
RLAWRAAPLPEPGPGEVRVDVAATGLNYRDVMWSMALLPEEALEGGFAGPTLGLECAGRV
AALGAGVTGLAVGDAVVSFGPACLSSHMVTDAAWLTRLPDGLSPEEAATLPVAFFTAFYA
LEHLGRMRPGETVLIHGGAGGVGLAAIQIAQWRGARTIATAGTEAKRAYLRALGVEHVLS
SRDLTFAAEVRALGGVDLVLNALAGEAMERSLGLLRPFGRFLELGKVDFYANTGIGLRPL
KDNVTYHGVDIDRLLRHDPALARELFAQVMTLFGDGALAPLPVRAFDGTQVQEAFRLMQR
SGHVGKLVIRPPATPRAAPPDAPVLFRPEPEGVVVIAGGGSGLGLALAARLVRNGARKIA
VLGRRAEPAPALLLEMARAAEQGAEIRPVCCDIADAAALEDSLQTLRNWGPLDLVVNSAM
VLQDMRLADLSAPVLKKVLAAKVTGTRNLDHATRGDALRGFVVFTSMATLIGNHGQGAYV
AGNAWAEALVRQRRAAGLPGLAVGWGAIDDCGYLTRDAETAQVVRRFGGGVRFGVAQALR
ALDELLAFDQQEDADPVIWVSPMAWAAPAASLRLLRGPMHQVLRALGQQSGEGPEGDDLR
ATLATLSSEAAEKRLTGFLLREVARILRVPESGLSATRPVADFGVDSLMGIELGLAAQQA
LGDDIPLMAISDAQSMAEIARRIVAHIQGTGPGAGDSGLGDLAAQHLGAASAGRTSAPDG
LPARRAAGGGGAMEAAE
>K9Q6T9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc sp. PCC 7107|TrEMBL
MTQDNKNKIAIIGMDAFFGECNTLDTFERSIYDGKQHFIPLPEKRWYGINEQKDLLQEYG
LIDGKPPVGAYIKDFEIDTLAYKIPPNEVEQLNPQQLLILKVAERAIKDAKLPEGGNVAV
IIAAEAELSVHQLQQRWDLSWQIKDGLNAAEITLPAEKIAQLETIVKDSVHQQVEIGEYL
SYITNIMASRISSLWDFTGPAFTLTSVETSAFKALEVAQMLLMTGEADAVVVGAVDLAGG
VENVLLRHQTAKINSGVNTLSYDQKADGWTVGEGAGAVVLKRYDVAQENGDRIYATIDAV
SIGQSLVNSANEAFHSAGVQPSQVKYVEVCASGIPQEDETEITSLLQAYPSVGNGLHCAI
GSVKANIGHTQVASGIASLIKTALCLYYRYIPGTPNWSGVKTPQQWEGSPFYVATESRPW
FLGKDSDLRIAAINGVGCDGTYAHLIISEDPTQEERPSRYLEQMPYHLFPIAADDKDSIF
AALNSLQKSIETSSSLSESASQAFAAYKANTQAQYAIAINGRNKKELLKEIESARKGVKT
AFDKGTDWQTPVGSYFTPKPLGQSAEIAYVYPAAVNSYVGMGRNLFRLFPRIFNDHMVKS
IHKRVADVELRVFPRSLSKLSLRQLETLEKQLLDDSLAMFEAEMFFTRLLTTIIRDDFQL
KPKYVFGYSLGETSMMVAQGVWSDFFQGSSSFNSSALFGSRLSGPKNAVREFWGLPNTDN
SDKTFWGNFVLMTSPEQVQAAIKNEPQVYLTQINTPEEVLIAGEPAACKRVIAALGCNSF
VAPFDHVIHCETMRSEHGELVKLNTLPSQNLSGVTFYSAAEYQPIVIESGAIADHIATGL
CQQLDFPRLVNRLHDDGARIFIEAGAGGVCSRWIDKILEDKDHITVSLNRRGMDDHTNIV
KALAKLLSHRVAVDLSPLYNLAPTTKQNKATLRTITVGGKSITASILTEENRQLFQDLAT
KAKDIQAENLHSNIPFPDEVDIIKSLQDTHKILGGEILTQNAEVSRKDIIEHGFTAAEKL
ESSELIATPNQASAINHDLDILIRMLELNTSHCQKLNANNARITQAHTAFLQARQDFSKQ
MGEIIQLQLVCAEDLLKE
>A0A654SE57|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Chrysosporum ovalisporum|TrEMBL
MEELTQNKIPKIAIVGMDCYLGGNCQGLDIFEQSVYEGIQHFVPLPEQRWQGLEKQEQLL
KQYGFTSGKPPLGAYIKDFEIDALRWQTVPEKVDKFNAQELLMLQVADHALQDAGLHPGS
RIGVVIVSSTELTLSENTSLEYPQIEKELANYVSQMWNFAGPALTLTAEQNSVFKALELA
QKLLAMKEVDAVLVGAVDLAGDSASVLLRNQIAAINTGVNTLSYDEQANGWMVGEGAAAI
VLKLHETAIQHNIRIYAVIDALSLVENVISQIHSIPTAIDAKAITQVCERAFQLANIKPT
DVNYLEVIGSGIPSQDESEIQGLLQAYGTYKANLNCALGSAKANFGHTYAVSGLVSLIKT
ALCLYRRYIPVVPQWSSPKMPEIWQDSPFYVAAQSKPWILEQGVTKRIAAVNGMEVDGSY
AHLILSEELGQEKHSHRYLEEIPYYLFAIAGDDYSSLLEQIDILQETIVNCSSLAAAASQ
TFKTFQKYQQATYTLSILARNQDELMREIHRSMEGVKIAFETGKDWQTPLGSYFTAKPLG
KQHQVAFVYPGSFNSHIGIARNLFRVFPQIYDDLAIRSVYNRVAKIEKILYPRSLKKLST
KQLEALEYKLINDPLTMLEAEVGIAGFMTAILRDYFQVKPKCAFGYSLGEISMMFAQGVW
TAFKQSSEGLNSSPLFKTRLSGPKNAVREYWGLPTQDHDDKNFWGNYVVICPLSQVREAL
KQEKRVYITLINTPEEIVIVGDTQACQRVIESLNCHAYHTPINHVIHCDPMRSEYEELVK
INTLPVQDIRETVFYSAAEYKPITLDSSSIGHNIAQALSQELDFPKLVKNVYNDGFRIFI
EVGVGGNCSRWIGKILEDKEHIAISLNRRGVDDHTSIIKALAKLLSHRVEIDLSLLYSPC
PPNFIPNQLAIETITLGSRKPNHISLTENQQEIFTNKFSTQHQSELLEANEYAKPIYAVN
LNLTTTGNKGMMNNLISKTTNKTSTFLVSDRPTYITEGQSPDQEDCQSILDSDCITDRHI
GKNQLPNLRHPQYQKLSHNLVRMTETHASLLELRQQSLHQISAIIQQQLELYQNLLKEVN
P
>A5G641|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Geotalea uraniireducens (strain Rf4)|TrEMBL
MKKIFNFQLTLDNPIVKSHQVYGHSVLPGLAYIDMLYQLAKDGLNLSSDDHCLKRLAIYK
PLVVSKEKPVRVKITFERKQRNWKISVAGVETDIHKESQAGMLYVTAELQKKVDFLEEVI
DVEAVKQLSTKTYDMETTYSEARKAGLVHQGMIKATGNVYITDSGCLIDVNANLANQDTA
QNYLFHPALMDGAAMSSMILIREGMPDSIADLYLPLSYETFYSKGPLLDRCYVRIERSSI
RTVNDITTVDMDFFDTGGHLTAKLSGLTIKLVKDPSQIDPERVKAEQAERDDNISSPVHE
DGGNVRHASLPSVEEPLKKIFAKYVNTNMDQLENLGFLELGMESSQLLELVKDIEEQFEL
SLSPSLLFEYSNFIALAGYLEKKLAEGGTKSQNWSTESGTLTIPSDKYEFYGSEPFLQDH
QVYARPAIMGVTYPCLAIETYLKNNPEGYPLGLRNIRFYGGPVGLNKNETVEVEVKSKGV
NGFETLFGTSNKERNCAGDFIGTVDSIPERLEIQSIVSQSKMFAPGTIEKIYKMIHDIKI
EKTLKTIEALYAYDKVTLVAKITMAGSQKRGNSENLVFDPLLLNSCYLMADPVTVDPEIK
VPLSIDSITVYRPTTEIAYVIKKIRVEKSDYISFDAIVVTETGEMIAKILNATLQKVGSS
VQLKNLDPVLNGNIEKKKGPADIAIIGVSVRYPGASHINEFWNNLKEGKSNITEIPQERW
NWREYFDKEKGKAGKMYSKWGGFLEDIDKFDHQFFNISPREAQIMDPQERLFLQETYSCI
ENAGYTPDTICDSRKIGVFVGVMNADYFKGSHPFVIANRVSYTYNFQGPSMVVNSASSSS
LTAVHLALDSLHSGACDRAIAGGVNLILSPNHYTILSALGVLSATDRCSAFGAEADGFVT
GEGVGAVLLKPLAQAINDGDNIYGIIKGSMINNGGRTNAFMAPNPVSQGQVIREAIERSG
VNARSISYIEANGTGTPLGDPVEISGLTKAFQHHTDDKQFCAIGSVNSNIGHCECAIGIA
ALTKVLLQMKHGKIVPSLFAENLNPHIDFENTPFVVQRELTEWKSDAPRIAGVSSFGAGG
SNAHVVVAEFVGKDDDSCNVSEGTPAIFVVSAQNAERLNERVKDLIEWLEGETFGDERLM
QVAYTLQVGREAMKSRLGFTAKTNKEAIEKLTCYLNRENNNARIFFGQAKKHSKMPSATP
ADGKEQEAVHKWMSSRNYEKLAALWVKGSVIDWNKLYEGKKPRRISLPSYPFAQESHWMV
MP
>K9ZNK8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Anabaena cylindrica (strain ATCC 27899 / PCC 7122)|TrEMBL
MNFQHNGLEIAIIGMSGRFPGCNNIDEFWENLKAGVELTSVFTNTKLAKTDTEQKIKAGG
ILSDVELFDAAFFGFNPREAEAIDPQHRLFLECAWEALENAGYNSQLETRPIGVYAGVGM
GTYLLYNLSPNQGWIESKGFLQTLVGVDKDYLASRVSYKLNLTGPSVSIGTACSSSLVAI
HLACQSLLSGECDMALGAGVAVKVPQNELTLSPDEIVAADGHCKAFDSRANGTVGGNGIG
VVVLKRLEDAIADRDRIYAVIKGSAINNDGAGKVGYTAPSQEGQTRVIRTAQMMAEVEPE
TITYIEAHGTGTALGDPIEIAAMTQAFRATTDEKNYCAIGSVKTNVGHLDAAAGIVGLIK
TVLALDHKLIPPSINFESPNPQIDFDNSPFYVNTKLLEWKTNDSPRRAGVSSFGFGGTNA
HIILEEAPPLEISSSARQQHLLVLSAKTSSALATATKNLAAYLKQHPDLNLADVAYTLQI
GRQNFNYRRMVVGENLEDVVKKLDFVDQELLTSSNRSVVFMFTGQGSQYVNMGKELYEQE
TIFREECDRCFDYLQHHLHIDLHSYLYPTETDIQTATQQLQQTAITQPALFVIEYALAKL
WISWGVSPVAMIGHSIGEYVAACIAGVFSLEDALSLVVTRGKMMQQLPAGAMLSISLPAQ
KVQSFLGDNLSLAASNAPLLSVVSGSIADITELEQQLTAKSIEYRRLHTSHAFHSSMMAA
VVEPFTLAVKKIKLHPPQIPFISNLTGTWMTPEAATDPNYWARHLRQGVRFAEGIAQLLQ
NAESIFLEIGPGRTLTTLTKQQASARVILSSLRHPQEKQSDVGFLLNTLGKLWLTGVQIN
WAGFYQHEKRHRLPLPAYPFERQRYWIDPPQQGNHHSQRLKLDNWFYLPSWQRSIIPTQN
LATANVSWLVFVDNTGFGDAFCQRLKTHYQHKVIQVKIGNCFSQINEQVYTINPQIREDY
EKLFQKISQLGKVPLIAHLWSLNPHESFEKSQELGLYSLLNLSYVIAKQKITESLKIGVI
SSDIQIVIGDENIHPEKATVLGGCKVIPQEQPNITCRSIDIVISKLGENELIDKLIVEIV
ADTSEDVIAYRNNYRWVQTFAAIPLEKTATTKQLRQKGVYLIVGGLGGLGLGIAEYLAKT
AQAKLALIGRSTLPEKSAWENWLMTHDEQDISSQKIRKLQEIEKLGAEVLVLSADVADEV
QMRSAVTQINAKFGAIHGVIHAAGVRGGGLAQLKTSAMIKAVFAPKVQGTLVLDTIFKDV
PLDFLVFWSSIAAFTGGYGNVDYVAAHTFLDRFAQCSSLPTITINWNAWQEAGMAIQLQE
KYKLQQSHLEILKNGITLEEGIEAFNRILVSGLSQVIVTPQNMQETMTQYANMGVIFADK
LADKTTVKANYPRPHLSNSYVLPRNQIEQTIADIWQEVIGIEKVGIYDNFFDLGGDSLIG
VRVINSIQEEFHIQLSTVSIFEAPTVSQLAQLLNPEEKEQFALQQRRSRGEMRRQKMQIQ
K
>K9ZQZ9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Anabaena cylindrica (strain ATCC 27899 / PCC 7122)|TrEMBL
MQTSNSDDKFRDTDIAVIGMSCRFPGAKNVAQFWDNLVNGVESITQLSQESLVASGIPSS
LFSKDNYVKSRPVLEDIELFDAAFFGYNPAEAELIDPQQRIFLETAWEALEDAGYVTENY
QGLIGVYAGGIFNNYSLRKISKEDNIDDHEMGNLLLANDKDYLPTKVCYKLNLKGPGINI
QTACSTSLVATHLACQSLLNYEIDIALAGAIAISLPHKAGYFYQEGGILSPNGHCRAFDA
KAQGTLFGSGVGIVVLKRLEEALRDGDRIHAVIKGSAINNDGSLKVSYTAPSVEGQAEVI
AEALANAGLNPETISYIEAHGTGTPMGDPIEIAALTKAFRASTQNKGYCAIGSVKTNVGH
LNAAAGIAGLIKTILALKHKMIPPSLHFEQPNPQIDFANSPFYVNSKLSAWNTQDSPRRA
GVSSFGVGGTNAHIVLEEAPEPAQSGKSRPWQLLVISAKTATAVDTATANLAKYLEQHQE
LNFADIAYTLSIGRQAFSDRRIVVSQNLDAAVKALKSQDSSTVFSQFQASQERPVIFMFP
GPGTQYVNITKELYQVEPAFRQHIDICCELLQPDLGIDLRQVLYSEKPPEIALFAIEYAL
AQLWISWGIHPVGMIGYGMGEYVAAALAGVFSLKDALKLVANKEKIAEIHLQSPQIPYIS
NLTGTWITTQEATDPHYWLKHLGKVENFNAGLEELCQQPGQILLEVGIGNTLSTLANQHP
TKSAQQVVLSSIGEDQSAVAFLLNTLGQLWLAGASVDWSGFYAHERRQRLPLPTYPFERQ
RYWIEPQTPISKVKKSDIADWFYLPLWKQSVISTQYQELAPQQSSYLVFLDECGLGWQLV
ERLQQQGHDVITVQVGTEFEKLSSYSLNPQSSDDYDALVQQLLLKQQLPHTIVHLCNVTL
DPEVINEWQTTGFNSLLFLAQALGKHPLMGEYRLVVISNHLQSVVGDEILSPQKSTLLGP
VQVIPQEYPNFNCCSIDIVLPVAGTWQYEKLLENLLTELRVASSEQLIAYRGVSRWVQTF
EPVRLEKAKDETPRLRPGGVYLITGGLGGLGLVLAEYLAKTVQGKLILTGRSAFPQRDEW
EQWLANHDQQNPITATIRKIQELETFGAEILVVNADVASLAQMKKAIACGQLQFGTINGV
IHAAGVPGGGVMQIKSIEEAHKILSPKVTGTLVLENIFQDVQLDFLVLCSSIAAIKGIFG
QVDYTAANSFLDAFARHKNSKNSTFTVAINWDAWQQVGMAAKASQQLVSTQTSAGLLPSE
GIDAFVRILSSKLSQVVVSKNDLHQTEQQLINHQAENFLATLEQINLSQPAHPRPLLSSA
YIAPRHEHEQTLINIWQEILGVSRIGINDNFFELGGDSLLAVRFISQVREKLRIELPINS
LFAASTVADLAKYFERETVSAGMSRICLREEGEL
>A0A378TF64|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium tokaiense|TrEMBL
MPPRDAAERLTFATWAIVTGKSPGGIFNELPQLDADTAAKLAQRLSERAEGTITAEDVTS
APNIEALATTVREFLEAGELDGFVRTLRKAESDDQVPVYVFHAAGGSTVVYEPLLNRLPA
STPMIGLERVEGTIEERAAVYVPKLLELNGDKPFILAGWSLGGALSYACAIGLKEAGADV
RFVGLIDCVRPGVPIDTSTEGTRARWDRYAKFAEKTFNVQIPEIPYEELEKLDDAGQVEF
VLNAVKDSGVQIPGGIIEHQRTSYLDQRALDVAEIKNYDGHVTLYMADRYHDDAITFEPA
YATRQPDGGWGEYVSDLEVVNIGGEHIQAIDEPYIAKVGAHMSQAINQIQANQGK
>A0A2K8QX37|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MPAASNQNKAVEALRKSFKEIERLRRQNRQLISSATEPIAIIGMACRFPGGVNSPEALWQ
LVADGADGISPFPTNRGWDVEGIYNPDPDHPGTSYVREGGFLHDADQFDSAFFGISPREA
LAMDPQQRLLLETSWEVLERAGIDPASLRGSQTGVFTGAMHTTYASEAAQIPDEIEPYLH
NGATTSIASGRVSYTFGFEGPALTVDTACSSALVALHLATQALRQGECSMALVGGATVMV
SPKGFVTFSRQRGLAVDGRCKAFADSADGTTWSEGIGVLLVERLSDARRNGHQILAVVRG
SAVNQDGASNGLTAPNGPSQRRVIRQALENCELTTSQIDAVEAHGTGTTLGDPIEAQALL
ATYGQDRPEGRPLWLGSLKSNLGHTQAAAGVAGVIKMVMAMRHGVLPKTLHVDAPSSHVD
WSEGQVELLAEARPWPETGEPRRAGVSSFGVSGTNAHVILEQAPEVEADTEAEEPAGGGV
AGPVAWAVSGKSDAALRAQAERLREYVAERSELGAADVALSLATTRAAFEQRAVVIGTSR
QELIERLEAVAEGAELPGVIHGSDAETPGRSVFVFPGQGAQWVGMAVGLLESSPVFAEAV
GECEAALSAYVDWSLTGVLRGVEGAPGFDRVDVVQPVLFAVMVSLARLWRSVGVEPDAVM
GHSQGEIAAACVAGGLSLGDAAKVVALRSQAIAVGLAGRGGMVSVGLSAEQAEERIARWG
GAISVAAVNGPGSVVVAGDPDALDEMVAELEGEEVRVRRVPVDYASHSAHVEGIREELLR
VLADLQPRSSEVPFYSTVTGELVDTAQLDAEYWYRNLRQTVELESTTRTLLDAGHTVFIE
ISPHPVLTLPVQQTVEAAESRAVVVGTLRRDEGGAERFLTSAAELHVSGARVDWQKVFAG
HGAHRVELPTYAFQHERFWLDAPAGVGDVGSVGLGSLGHPLLGAVVSLASGGGVLLSGRL
SLATHEWLADHAVHGVMLLPGTAFVELVVRAGDQVGCGRVEELVIEAPLIVPEKGGVHLQ
VEVGEADASGFREVSVYSREEADGDGAAWVRHAHGVLGSAVPSSETQYDFGVWPPVGAEL
VDVSGEYVRAAENGLEYGPVFQGLRRAWRRDGEVFAEVGLPEGERERAGQFGLHPALFDA
ALHALGVSGVLAGGSGSLLPFSWRGFALEAVGATSLRVRLASVGAGSDAVSVLVGDESGR
GVASVESLVLRPVDADQLNAVGGAARDGLFRVEWVDASGAVAAGGEVASRTEVVRVVSEG
ADVVGEAYGHVLGVLERVRAWVADEDLAGERLVVVTRGAVDVGDGVEDVAGAAVWGLVRS
AQSENPGRLVLVDTDDVEDVGGVLPGVLALGEEQVVVRSGVVRVPRLGRVPVSGEVSGVF
GSGAVLVTGGTGVLGGVVSRHLVARHGVGRLVLLSRRGAEAEGAAELRAELEGAGAEVVI
AACDAADGEALAGVLAGLPEGFALSGVVHAAGVLDDGLLTSLTRERVEPVLRAKVDAAWN
LHELTAGMNLSAFVLFSSATGVLGGAGQSNYAAANVFLDGLASWRRAQGLPGVSMAWGLW
AEASGMTGHLGEDDIQRISRSGVLPLATDEGLELFDAALVSDAVVPVLFRLDIPALRAQG
AELPALFRNVVPGMTVRRVAGAGDADVDDIAARLRRRLVSMSEADQEQFLLEELIRIQVA
AALGHANSDTVEVGRPFKELGFDSLTAVELRNRLSAETGLRLPATLVFDYPNPTVLAGHL
RSEILGSQGTATATPAAGGSAEALSRTDDDPIAIVSMSCRFPGGVRTPEELWHLVMGGTD
ATASLPSNRGWDLETTYDPDPAREGTYYARNGGFLYDADQFDPAFFGISPREALSMDPQQ
RLLLETSWEAFERAGIDPESAKGSRTGVFVGVVYNDYGTRLQGNAPEGFEGYLGTGSAGS
VASGRISYTLGLEGPAVTVDTACSSSLVALHLAVQALRQGECDLALAGGATVMSTQAGLV
DFSRQRALSADGKCKAFSNDADGFGFAEGVGLLLVERLSDARRNGHEVLALVRGSAVNQD
GASNGLTAPNGPSQQRVIRAALKTARLSGAEVDAVEAHGTGTSLGDPIEAQALLATYGQD
RPTDQPLWLGSVKSNIGHSQAAAGVAGVIKMVMAMRHGVLPKSLHIDEPSQHVDWSAGDI
ALLTEATAWPESDHPRRAGVSSFGVSGTNSHAILEQAPEVEAAEDAEAEAVGGPVAWLVS
GRSPEGLRAQAERLREFVTERPELDAAAVAFSLVTSRSVFEHRGVVTGADREELLERLGA
LAGDEVASGVTRGVADARGRSVFVFPGQGAQWMGMAVGLLESSPVFAEAIGECETALSAY
ADWSLTEVLRGAEGAPGFDRVDVVQPVLFAVMVSLAKLWRSVGVEPDAVMGHSQGEIAAA
CVAGALSLEDAAKVVTLRSQAIAVGLAGRGGMVSVGLSADRAKERIAAWDGAISVAAVNG
PGSVVVSGDPGALDEMVAELEGEEIRVRRVPVDYASHSAHVEAIREELLRVLADLEPRSS
EVPFYSTVSGELVDTAGLDAEYWYRNLRQTVELEATTRTLLDTGHGVFIEVSPHPVLTLP
VQQTVEAAEAQAVVVGTLRRDEGGLERFLTSAAELHVNGATVDWRKVFAGHRARRVELPT
YAFQRQRYWLDALSAAEVAAAGDGLSADAVDARFWEAVEREDLEALARTLEVEDEEQQSS
LTALLPALSSWRRQRRAQNTVDSWRYKAVWKPLASASESTLSGTWLVAVPEACGDETLAA
TVLDGLTGRGAHVVSVVVGAADDREAVVERLRVALDGVAVEPSDVAGVFSLLALDESGHP
AFGVVPGGLAAMVGLVQGLGDAGVVAPLWCGTRGAVSVGRSDRLVSPVQSMVWGLGRIVG
AEYPQRWGGVVDLPETMDSRALVRLAGVLAGAVGEDQVAVRGSGVFVKRLVRASASEGTG
VGGWRSGGSVLVTGGTGALGGHVARWLARTGAEHLVLTSRRGMEAEGAAGLKAELEELGA
RVTVAACDAADRDALAAVLDAIPSELPLTAVVHTAGVLDDGVVDALTVERAAGVLRPKVD
AAWNLHELTAGMDLSAFVLFSSAAGTLGGPGQGSYAAGNAYLDALASQRRADGLPATSIA
WGAWAGGGLVSGEVGEQMSRSGMLAMSPELAISALHQALDHDETFLAVADIDWTRFEADS
VDSPLFRELRGARTTATGKQSTPGGAEPGRAELHDRLEALPREKREAALRDLVRAQAADV
LAHDSADAVASDRAFRDLGFDSLTAVELRNRIGAATGLRLPVSLVFDYPTPTVLARFLNG
EMFGTEEGGAAEVTPTRSDSFDEPIAIVAMSCRFPGGVRTPEQLWDVVNAGVDTISGFPD
DRGWDLDGLYDPDPDKPGKTYALTGGFLDNVSDFDPDFFGISPREALAMDPQQRLLLETS
WEAFERAGIDPAALRGSQAGVFIGSNYQDYSGRAISAPDGVQGYLGLGSASSVASGRLSY
TFGFEGPAVTVDTACSSSLVALHLACQSLRQGECDMALAGGVTIMATPGTFVEFSAQRVL
SPDGRCKAFSAEADGTGWSEGVGLLLVERLSDARRRGHKVLAVVRGSAINQDGASNGLTA
PNGPSQQRVIGKALENAGLSAADVDTVEAHGTGTSLGDPIEAQALLATYGQERSEDQPLW
LGSIKSNIGHTQAAAGVAGVIKMVMAMREGVLPKTLHADEPSPHIDWTSGAVSLLNEATA
WPETDRPRRAAISSFGISGTNAHTIIEAADPVESPSPETGGEATGSSAGITVVPWLLSGS
NADALSAQAGRLREFDGVRTARAGDVADIGYSLATTRSALPYRAAVVAEDPAQFRSGLEA
LAAGGNAATLIQGVARAEHKTAFLFSGQGAQRLGMGRELYDAFPVFAQALDEVCAYLDVL
LDRPLTEVMFAVEGSADAELLNQTAFTQPALFAIEVALFRLLEHWGVTPDVLIGHSIGEV
AAAHVAGVFSLEDACALVAARGRLMQALPEGGAMVAVQAPEEEIAASLAGREAEVSIAAI
NGPTAVVIAGDEPAVLEIAGQWEREGRKTRRLRVSHAFHSPRMDGVLGDFRKVVEGLLFA
PPTISLVSNVTGAPADADEVCSPEYWVRHVREAVRFADGVRTLENLGVTSFVEVGPDGVL
TAMAQDCLTAAEPGGAVAPALVPVLRKDRPELQSLTMALAELHVHGATVKWDAVFAGRGA
QRVELPTYAFQRQRYWLEAAPAASGDVTSAGLDSPDHPLLGAAVALADTDTYLFTGRLSV
ATQPWLADHAFADTVLFPGTAFVELALRAAEQVGYERVEELTIEMPLVLPVRGAVQIQLA
VGEPDESGARSLNLYSRPEDAHPDDPWTRHTTGLLSRDPSTTAPESVAADFAVWPPAEAE
AIDVADLYDRFIDVGFAYGPAFQGLRAAWRRGDEVFAEVDLPETQEGEAARYGLHPALLD
ASLHTVAFKPSGSDGSTLPFSWNGVTLHASGASALRVRLTSVGEDTVSLHVTDVSGALVA
SVDSLVLRPVAPEQVNSAQPHESLYQVDWVPTAPETSGADAGRWALVGPDRAELTGALGS
ADVTVDTYPDLAALAEAIDAGATAPDVVLAANVSRTGRTRELAEAVREAGHHALDLLKSW
LADNRLGGSRLVFLTRGAIAAGDDTDVADPASAAVWGLVRSAQSENPGRFVLADLDDREG
SRRVLPAALTTDEPQIVVRNGTVLAGRLARVAAHGSASEQGDARSVTTGVTWDPQGTVLV
TGAASGLGGLVAKHLVGEHGVRHLVLVSRRGLAADGAAELRTELTDLGAHAMVAACDTAD
RDSLAALLASLPDEHPLTAVVHTAGVLDDGVVEALTPERVDRVLRPKVDAVLNLHELTAG
LDLSAFVLFSSLSGTLGGTGQANYAAANAFLDAFAHRRRAEGLPAQSLAWGLWEERSGMT
GKLDEAHMRRLAREGVTPMSSEEALALFDAARGIDAATLVPARLNAAAWRAQDGPIPALL
RGIIRTTARRGPAKASTGGSGADPAELRRRIGSMNPAARQQALLELVTEHAAMALGHDSP
RMIAPDRGFLELGFDSLTAVGLRNQLGTVTGLRLPATLLFDYTTSRALAGYLAQELVAEE
PDASLVLPVLSELEKLERSFAEVVADEAATARLTSRLQQVLAKLTAGQQTETANGGVVAA
DKFESATDDEIFDFLDEELS
>A0A2K8QX54|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MSEQEKLLGYLRRVTADLHETRGRLRELEALAGEPIAVVGMACRYPGGVTTPEDLWHLAR
EGTDAITPFPDDRGWDTEAIYDPDPDAPGRTYTRAGGFVTDVGHFDAGFFGISPREAQAM
DPQQRLLLETSWEAVERSAIDPSSLKGRDVGVFVGAGLPDYGPRLHAVDDGMEGHLVTGS
SPSVVSGRIAYSLGLEGPAVTIDTACSSSLVALHLAVQSLRRGECSLALTGGVTVMSTPG
IFIGFSRQRGLAPDGRCKPFSAAGDGFGPAEGAGMLCLERLSDAHRAGHPVLAVVRGTAI
NQDGASSGLSAPSGPAQERVIRAALEDAGLSAGDVDVVEAHGTGTKLGDPIEADALLATY
GRGRDPERPLWLGSVKSNIGHTQAAAGVAGVIKMVSALRQGVVPRTLHVDEPSPHVDWST
GTVRLLTDPLDWPRGDQPRRFGVSSFGISGTNAHIIVEEAPVPDGEPQESPAPTHECELP
LAPWTLSAKSEAALRDQAGRLAAHLVRHPDHTLADIGHTLATTRTAFDHRAVLLTPGLPH
AIDQLTHHASGRETTELITGSAHHGSGPVFVFPGQGSQWVGMALDLVESSPVFARRMGEC
ADALAPLVEWSLWDVLGDEVALGRVDVVQPVLWAVMVSLAEVWCSFGVVPSAVVGHSQGE
IAAAVVAGGLSLEEGARLVVLRSRVLVGLSGRGGMVSVGAGVGVVRGLVESFGGGLCVAA
VNGPSAVVVSGDVGVLEGFLAECEGVGVRARRIPVDYASHGVQVEEVRGEVEEAVSGVVS
GVGVVPFYSTVTGGVLDMAGLDAGYWYRNLRFPVRFEETVRVLLDAGFRQFVEVSAHPVL
TLGVEQTAEDHGVEVSVVGTLRRDEGGRGRVLRSLAQAYVAGAPVEWARVYGDTGARRVD
LPTYPFQRQHYWLAPSAPADAAAIGMESIGHPLLDAGVPLPDSDGHFFTGRWSLRTHPWL
ADHTVRGRTVVPGTALVETVLRAADSVGCDRLDELSLETPVVLPEDGGVLRVQVTITGSE
GSDGRRYVSLHTCGADGVWTRHARGTVLTAGVSGEPAGLGSWPPAGARPVETAGLYERLS
DEGLGYGPVFRGLETVWRRGEEIYAEAALPEVARRADDGFGVHPALLDAALHAWAAGSDD
AGSDDAGPGAVRLPFLWSGVTLHATGATKLRVRLTPVIGGGMSVLVADDTGRPVASVETL
VTRPLGEGGGDPADTHTTAAPHRVEWTPLPAMDTEGRARRLAVVSGEALGLDRLADGYED
LADLAGQVAAGECPPPDYVLAGIAPCAGTDVASEAVSTAGRALSLVQDWLADETSAATGA
RLVLVTRGAVAVATGEGVSDLAASPVWGLVRSAQTEHPGRFVLVDLDADEGSISALPAAL
DTGEPQLALRRGELSIPGVAAVPATPKLPDGPWRLKVDPDGELDGMSLVPCDAATRALGA
QEVRIEVRAVGLNFRDVLVLLGMYPDAESAVLGSEGAGVVVEVGSGVTDVCVGDRVMGVW
GDGFRSVVVVDVRGVVGVPVGWSFEQAASVPVAFVTAYYALVDLAGVRAGESVLVHSAAG
GVGMAAVQLARYLGAEVFATASESKWSVVRGLGVSGERIASSRSVEFERVFGSGVDVVLD
SLAGELVDASLRLVRPGGRFVEMGKSDVRDAGEVAEAFGGVWYRAFDLAEAGVERMGEVL
REVVGLFEAGVLELLPVGVGDVRRAGEVFGVMRRARHVGKLVLSVPSAVDGGGWVVVSGA
SGVLGGVVARHVVVERGVRRLLLLSRRGEDAPGVEGLVAELVAAGAEVRVVACDVADRDA
LAGVLSSLEGGVSGVVHAAGVLDDVMVESLSAERLAGVLAAKVTGAWNLHQLTLGHDVQS
FVVFSSAAGVLGAAGQANYAAGNAFLDALAAFRRSRGLPGVSVAWGLWEQRSVMTEGLGD
IDLTRIARTGFQELSTEDGLELFDRATESPESLLLAARLDPRALGTADPNAPVHPMLRTL
VRRPVAPRRRALAAPEAGPEAGTEADGPTALRRRLLAQRPDDRRNTVLDLVRTRVSAVLG
HDDLGAVAPDLAFKDLGLDSLTAVDLRNRLSTATGLRLPATLAFDHPSSSALAGHLLTEI
LGPDALAAHALGAEGEVLPATADPGSADATGSPDDHDLIAIVGMACRYPGGVTTPEDLWR
LVTSGGDAIGGLPTDRGWDLDALHDPDPDAPGRTYVREGGFLYDAGRFDAEFFGVSPVEA
LAMDPQQRLLLETSWEAVERAGIVPAALRGSRTGVFVGSHYQEYGPRLHEAGQGAEGHLL
TGTAGSVVSGRVAYVLGLEGPAVTVDTACSSSLVALHMAVRSLRTGECDLALAGGVAVMP
GPGALIGFSRQRGLAADARCKAFSEDADGTSLAEGAGVLLVERLSDARRNGHRILGVVRG
TATNQDGASNGLSAPNGPAQQRVIRAALADARLAPADVDAVEAHGTGTRLGDPIEAQAVL
ATYGQDRGGARQPLWLGSIKANIGHTQAAAGVAGVIKMVQALEHGVLPASPHLRRPSEHV
DWSSGDVALLREPVAWPAADRPRRAGVSSFGISGTNAHVIVEEAPPADGIVEEAPPEDGA
APAPSPSQAGTTVPWIVSARSADALRDQARHLLTHLRHGRHVVRTGVPADAADVATALAT
QRSVFEHRAAVLGERQEDLTTGLAALAAGRPAPRLVTGTAATGRTAVLFTGQGSQRVGMG
RTLHAAYPVFADVFDAACAHFDALLPGRPAVRDVVLGEHEGAERELSRTLYAQCGLFAVE
TALYRLVESWGVRPDAVAGHSIGEVVAAHVAGVLTLPDACALVAARGRLIQELPDGGVMV
AVRAAEADVLPLLAGHQGAVGVAAVNGPEAVVLSGTRDAVEKVVAVLRERGAETKRLDVS
HAFHSPLMEPVLTAFRDEVSRLAFAAPELLVMSHLTGEPLPADRPCGADHWVRHIREPVR
FADGVTALAAQGVTTFLELGPDGVLSALGQDCAPDAEFLPSLHADADETASLTEALAHLF
VRGTDVDWSAVARVPGRTPRPVRLPTYAFQRADYWLPSTGVAAHRDDTPDGRLRDAAAHG
DDAALAAELTLGDAESTAALLPLLAAYRRRRRDDALVDGWRYRTTWTPVAVPAAEPAGTW
LVAVPERLAADPWVTRVTEALSAGGATPVTVPVTHPGGLAGELGDAMAGAGPVSGVLSLL
ALAAGTDPEHDAVPQGVALTLALSRALDETGVRAPVWHATRSAAAVGGGERVRGPEQFGV
RALGRVAVLETPERWAGTIDLPEHLDGWVGDRLGAVLAQGVGESEIAIRGWGVFARRVVP
ATAPVPGSAPVPGSAPAAPAARPWPSTGTVLITGGTGALGRQVALRLARAGAGHLLLASR
RGPAADGAAALRDELKALGAQVSLVACDVGDRAAVAALLDGIPADRPLTAVVHTAGAIDH
GDLTEMTTARFQAVARARSQGARHLHDLTRDRDLTAFVLFSSLTGTVGAAGQAGYAVANA
LLDALAEERSAAGLPVTCVAWGPWADTGMADAGGAGGRAVGHGGLTPMEPDLALRALERA
VAAGDSRVAVLDADWPRFAGHLADDPGARPLARLLDGIPAVRQAATAVASPGPHSPEEFG
KQLQALAPAEREAELLRVVCTHAAVVLGHGTPDVIAPGRGFVEMGFDSLTATRLRNRLAA
TTGLQVSAATVFAHPTPDTLAAHLLGLYDAPRPRERPRLRPRGRD
>A0A4P7C5U5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Saccharomonospora xinjiangensis|TrEMBL
MARSELIRPLSELLRAHAGRRGEKVAYSDARRSVTYAELEQRTARLAGHLADRGLSRGGR
VLIWFNNSVEMVEGYLTSVRAGGVGVPVHPRASDDELAYLIEDSGAEVVLTDAAHLEQLH
RVSGDANLVVVAAGQVKPATAGGVSSFEELATTEPASPARDDTGLDDLAWMLYTSGTTGR
PKGVLSTQGSCLWSVAACYVPLLGLSPEDRVLWPLPMSHSLAHILGVHGVIAAGASAHIT
DGFAGDEIARLMREESYTFLVGVPTMYHDLLRHARTEGLDADSLRVCMVTGAVTSASLSR
SFEDTFGVRLIDSYGSTETCGAITMNRPTGPLVAGSCGSPVPGLKVRIVEPGTGKEAEPG
VEGEVWVKGPTVMLGYHNQPEATAAALRDGWYRTGDLAVRDELGYLTITGRIKELIIRGG
ENIHPAEIEDVVSTVAGVADAAAVGRPDAELGEVPVVYVVAEVPGEVDAEAIVMACRRHL
SYYKVPSAVYEVEAIPRTASGKVARRKLLGTQAREHSTGSTVLAGLSRIDWTPIAGGPSR
RPEPGEWAILGADEFGFAADGIPVSAYADLAALGDAVEAGTPAPRTVLTDAPASVEHARA
LVESWLGDERFAATRLVVVTRFAVGTGSEAAVDPSGAPAWGVVRAAGDTDRLGLVDVGEA
MLAELITAVGAGKPEVAVRDGVLRVPRLAPVRVPSTPSEPAAGTAMVVGDEAGIVAAHLS
SRGFGAVVTVGEDEIADVLTQVPDEHPLHTVVYAVEGDPAERMAGARLLHEVTRDAAPAA
FVLLCPVESLLGRGTEPGEAAAGAFLSALTQQRRAEGLASLALGVPADQSTQDFAALLDI
TQATDEAVLLAVEDDALTEAPAPARSESSQPQAGALRERLTGLTRQEQDRLLLALVRTET
AGVLGYGNPARIPARRAFKELGFDSKTAVELRTRLASATGLDLPATVVFDRPSAAELAEH
LRAELLGLRTEATRVHERAESAAADDPIAIVGMACRLPGGVNTPAELWKLAADGVDALSG
FPVDRGWDLAGLFDDDPDRAGTSYVREGGFLHDVAGFDAGFFGISPREALAMDPQQRLLL
EVSWEALEHAGIDPQSLRETDTGVFAGMMFHDYGGDRTRAPEDLEGYLGTGNAGSVLSGR
VSYVLGLHGPSVTVDTACSSSLVALHLAAQSLRTGECSLALAGGVAVMATPSVFVEFSRQ
RGLAPDGRCKSFADAADGTGWSEGVSLLVVERLSDAVRHGHRVLAVVRGSAVNSDGASNG
LTAPNGPSQVRVIRKALESGGLRPSDVDVVEAHGTGTRLGDPIEAGALVEVFGSGRRGSP
LLLGSVKSNVGHTQAAAGVAGVIKMVESLRRGVVPGTLHVDAPSSRVDWSSGAVELVTSA
TEWPEVDRPRRAGVSSFGVSGTNAHVIIEQAPEQPEAPEPGAAPTIWTVSGRSEKAVRAQ
ASRLLSAVDTLNPVDVGYSLATTRAALDFRAFAAGDNRDDLHEQLRAIALGTTPVLPADV
EQGPVFVFPGQGSQWVGMVLGLLESSSVFAEAFGEVAGVVEGLVDWCVVEELGGGLDRVD
VVQPVLFVVLVSLARLWESCGVVPVGVVGHSQGEIAAACVAGGLSVEDAARVVVLRSRLI
AGVLAGRGGMVSVGLPVGEVVSRLPVGVGVAAVNGPSSVVVSGDVGGLEGFVSGCERDGV
RVRWVAVDYASHSEQVGLVRDELLSVLSSVVPRSSSVPFFSTVTGGWLDTAELGAEYWYR
NLRETVRFSDAIETLEAEGFKSFIEVSPHPVLTMSIEESVVDGAVVGTLRRDDGGFDRFL
RSLGEAHARGVEVDWSAVFDGSGARRVDLPTYAFQHERYWLESTPAAGDPAGLGVASAGH
PLLGAAVDLAGGDGLVLTGRLTTATQPWLADHSVHGTVIVPGSAFVELALRAGRELGHDR
IDELTLEAPLVLDDTDTIVQVVVAPDGRGVSIHSRHTGDQTWTRHAQGVLASGAEPVSGP
LAAFRNWPPAEAQPLAVEDFYERLAETGLAYGPSFQGLRAAWRHGNEVFAEIRLPEPVED
AGEFSVHPALLDAAVHGVDLGVLEPGERRLAFAFSGVTLHAVGARVLRVHLAPAGQDAVS
LTAADETGALVVSVDTLVLRHTASPPRRRVAARSMYTLDWTAPQSPAPEPTRWAVLDPGE
HSAGGWLTAPGRCAGSYADLDALAGAVAQGEPVPDVLVAAGTPGAANPAAAARELLAEVS
ATVRAWLADARFGDSRLVLLTSNAVATGSEGATPDLAQAPLWGLLRSAASEHPGRFALVD
LDGEDSSFLALPDALALPEPQVAIRSGRVLAPRLARADATAAPRWNAEGTVLITGATGGL
GRLVARHLATEHGVRHLLLLARSAPSAEVAAEFGDLDAEVTFAECDVADRAALADVLSGI
DDAHPLTGVVHTAGVVDDGIVEALTGEQFDRVLSPKLDGALALHELTKDMDLSAFVLFSS
AAGILGTPGQGNYAAANVFLDALAAHRRRSGLPGVSLAWGVWAESAGMGGRLAETDLARM
ARGGTVALSAAEALALLDAATGSDAPALVPMGLDTTVLAAQDDVPELFRGLVRAQPRRAA
RAEPEDGLPLARRLAPLPVEERERMLSELVHTHAAAVLGHGSGSDLDGGRSFKELGFDSL
TAVEFRNRLSNATGLRLPPTLIFNHPTPGALAAHLAEELLGTANESGEPAAPPATSASTE
DDPVVIVAMSCRFPGGVDSPERLWQVVADEVDTIGPMPEDRGWEPDRLYDPDPEQPGKTY
LVEGGFIEGLGRFDAEFFGINPREALAMDPQQRLLLETAWEVFERAGIDPRSLRGAQVGV
FTGTHGQDYGALLDGAPPDLEGYKATGTAGSVVSGRLSYTFGFEGPSMTVDTACSASLVA
LHQAANALRGGECSMALVGAASVMSTPEPFVMFSRQRVLARDGRCKSFAAAADGTGMSEG
VGMLLVERLSDARRLGHPVLAIVRGSAVNSDGASNGLTAPHGPSQERVIRQALADAGLTG
GDVDVVEAHGTGTALGDPIEAHALLATYGRDRSPEHPLWLGSVKSNLGHTQSAAGLAGVI
KMVLAMEHATLPKTLHVDAPTPHVDWELGGVRVLSDAREWPSNGHPRRAGVSSFGISGTN
AHVVLEQPPSEAPSASPATPAPLTSALPWVLSAKTEDALRAQAERLREHVENLAEVDVAS
IGLSLATSRTAHPHRAAVIGREIPEFTAGLDSIVHGTDAPNLVRALATPGKVAFVFPGQG
SQWPEMATDLLATSPVFADRLRDCDEALREFVDFSVLAVLRGEPGAPALDRLRVVQPVLF
SVMVALAELWRSRGVHPAAVVGHSQGEVAAACVAGALSLEDAARVVALRSRLIDEELSGK
GGVVSVALAADELAPRLARWGEKLSIAAVNSPTAVAVAGDPEALDELMAELEADQIRARR
IRGAHAAGHTAQIDRLRERLLEELAPVTPRADAVPFYSTVTGAAVDPSTLDAEYWYRNAR
EPVLFEKAVRALSAEGHTAFVESSPHPVLLGAIQETVEDAAVIGTLRRDDGGQDRVVTSL
AEAHVRGVVVDWAAVFPSGARKVSLPTYAFQRKHFWLDRSTAASDVTSAGLDPAGHPLLG
AAVPVPQFGGFLCTGRLSAHAQPWLTEHPSGVNIVAPAVFVELALRAGEEFGCDRLADLT
VEAPLALPEQGGVRVQVTVGGPDDEGRRAVAVYAQPDTDAGREWTLHASATLTAREGTQP
APLAVWPPEGATELGHDAATGVRRAWQRDGDLFAEIVVPEESATGEFGLHPMLLETAVHC
AGPLRGRPAGTVAARWRDVTLHATGARALRVHLSEREPDALSLAAFDETGSPVLSATVET
RPVDGFRAALGHGDALFRLLWTELSLPDTEPGNGMVLGEDHADPAELASAIAGGAPVPDY
VVVPADPGTGSTENTENTENTENTAEAAGACALRVLTLLRKWLAEERLAPVTLVVLTTGA
VATGADEDVPGLAQSSIWGLVRSAQTENPGRVVLVDVDTHEAPAHLLPAVVASGEPQAAI
RAGTVLVPRLARTRPAEQPVAPAFDAEGTVLITGGTGALGALLAEHLVTAHGVRHLLLTS
RTGNRSSSAARLCDRLGALGATVTVESCDVADRAALESLLSRIPSAHPLTAVVHAAGVID
DGVLDSITPERLDAVLRPKVAGALNLHELTEGLPLSAFVLFSSGAGIFGSPGQANYAAAN
TVLDALAHHRQHRGLPARSLAWGLWAERGDQSSGLGETDLARLARTGTVEIPAEHGLALF
DAARTACDALVVPTRLDFAALRAQARAGSLPHLLRGLVRVAAKTASAEPEGSSLAARLST
SSPAERRETVLQLVRSTAAAVLGHTGLDTIGARRAFREVGFDSLTAVEFRNRLQAGAGLR
LPATLVFDHPTPQAVTDHLLSELFGDPGSDAGPRAVATERADSATEPIAIVAMSCRFPGG
VRSPEELWRLLEAGGDAITELPSDRGWDLESLYHPDADQPGTSYVREGGFLHDAAEFDAG
FFGISPREAVAMDPQQRLLLETCWEVLERAGIDPTSLRGSRTGIFTGTTGQDYAALAEHL
PQSDEGFLVTSTGASVLSGRVSYTLGLVGPAMTVDTACSSSLVALHLAAQALRSGECTLA
LAGGATVLATPRTLVAASRQRGLSPDGRCKAFSDDADGFGMAEGAGILLLEKLSDARRNG
HPVLAVLSGSSVNQDGASNGLTAPNGPSQQRVIREALDAAGLTAAEVDVVEAHGTGTSLG
DPIEAQAVLATYGREHGNDNPLWLGSVKSNIGHTLGAAGVAGVMKMVLAIQHGVIPKTLH
AETPSTHVDWTEGAVALAREAVPWPDTGRPRRAGVSSFGISGTNAHAIVEQAPDTEVTEP
ERTLSLRRVPVVVSARSAAALAGQARRLGDWLAERSDLTDLTDLTDLAFSTVTSRAALEH
RAVITAESRDELMRALRALADGGVASNLVRGEQRDEVTCAFVFSGQGSQRPGMGRELHET
YPVFARAFDEVCAKLDARLDGYADHPVREVVFAETPDGAELLDQTVYTQAGLFAFEVALF
RLLTHWGVRPGYVLGHSIGEVAAAHVAGVLYLDDAATLVAARGRLMQALPSGGAMVAVEA
SEEDVLPLLDGAGTVGIAAVNGPKATVLSGEEDAVLAVAAALASRGAKTKRLRVSHAFHS
PLMHGMLDEFTTIAEKLTYHAPVIPLVSNLTGQLATDEIRSAGYWARHVAEAVRFGDSVR
RLAGQGTDVFVELGPDGVASAMAADSAGEQALTVATCRKDRPEPVTLIGALARLHANGVS
PDWAAFFSGTGATRTELPTYAFQRRRYWLDAPSRPAEAEQSWRYRMDWQPIPTTAAPVLP
GHWLLVLPDGAIDDATDDAWRATLLEGSGAQVSTVHLDPAGDRGTAAERIRAAVGDSAIT
GVLSLLGLDDRAHPAHPSASLGLSATVLLLQALGDAAIDSPLWCATQGAVATEPGEAVTS
LTQAQLWGLGRVAALEYPGRWGGLIDLPPSPETARHHVIAVLADARGEDQLAVREAGVLA
RRLVRAEPVEGGTEWVPSGTVLITGGTGALGGHVARRLAAEGAEHLLLVSRRGPDAPGAA
ALAEELTGLGARVSVVACDIADRDGVAALLADIPDQHPLTAVVHTAGVVSDGVLDTMTPE
KIAEVMRPKADAALHLHELTRHLDLSAFVLYAAMAGAVGSPGQGNYAAANAFLDALAERR
RAEGLPALSVSWGWWEGDGMAKLDGVDQSRLRRNGLLPMAPERAVAELFDALRTDDATLL
VTNVDWPRFVPAFTTTRSSALLEPVTVRVAAPTATQAVTVADEPDAVSDLLGRLAGADAT
ERARLMLDLVCSHVAEVLGYDSSDTVEVSRGFLELGFDSLTAVELRNQLTARTGLRLPPT
LIFDYPSPSALADWLTTQVLGGSGNGGDPREAEVRGLLASIPLTRLDEAGLLDDLLRLGR
GAENTDEGQANGEAEQLDDLDVADLVRLAREDLDR
>A0A445NG46|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces netropsis|TrEMBL
MVTDDKIRYLLKRVTADLHETRGRLRELEDAAGEPIALVAMGCSLPGGVRSPEDLWRLVV
SGQDAIAPFPEDRGWDVDGLYDPDPDRLGKTYAREGGFLADVASFDAGLFGVGPREALAL
DPQQRLLLEVSWETFERAGITPSSLRGSRTGVFVGTSSQEYAFLVRGARENFEGYSTGYL
ASVMSGRLAYTFGLEGPAVTVDTACSSSLVALHQAVQSLRAGECGLALAGGAAVMATPGM
FVEFSRQRGMAADGRCKAFAAAADGTGWGEGVGLVLLERLSDARRNGHPVLAVIRGSAVN
QDGASNGLTAPNGPAQQRVIRAALANAGLALSDVDAVEAHGTGTTLGDPIEAQALLATYG
QDRPAGQPLWLGSLKSNIGHTQAAAGVAGVIKMVMALRNGVLPSTLHIDEPTPHVDWSSG
AVELLTGNRDWPETGRPRRAGVSSFGISGTNAHLILEQAQQPEQAEPDAAPGTEPAGPVL
IGGAGGEDRRDTAPMPWTVSARTDRGLREQAARLRDHVRDHPELSPPDVGHSLLTSRTLF
DHRAVVLAGDLDGYVTGLDALAEGRVAPEVVAGVATDPGKPVFVFPGQGAQWAGMAAGLY
RDSAVFRDRLDECAAAVDPLVDFSLVDVVCGADGAASLDRVDVVQPALWAMMVSLAALWR
SYGVEPGAVVGHSQGEIAAACVAGALSVEDGARIVALRSRLVAERLSGRGGMAFLALPVD
RARDWLQAWETRLAVAAVNGPSSVVVSGDPGALDELLALAEGEGVRALRVAVDYASHSAQ
VETLEAELASVLAGITPQAARIPFFSTVTGAVADTSGLDAAYWYRNLRETVRFDPTVRAL
LASGHRTYVEMSPHPVLAVSVEQILDDAATEGVVLTSLRRDEGHLQRFLTSVSEAHVRGV
RVDWSCHLGPHRRLVDLPTHAFQRRRYWLDAAPDAAAREDDDSASTPFRQRLAELPAPEQ
RRVVLETVCEHAAAVLNLASAADVESTRAFTDLGFVSMTAMELRNRLATATGVRLSPAAA
FDHPTPEKLSALLLSRLTGTQEPATEAVRAVPVADEPIAIVAMGCRYAGDVASPEQLWDL
VASGRDATSSFPANRGWDVEGLYDPEPGRPGRTYVRRGAFLRDADQFDPLLFGISPREAL
AMDPQQRLLLEVAWEVFERARMSPETVRGSRTGVFVGIAGQDYLPLLTAAPEDSAGHLMT
GTSTSVASGRLAYTFGLEGPAVTVDTACSSSLVALHLAVQALRAGDCTAALVAGATILST
PGAFVEFSQQGGLAPDGRCKAFAGSADGTGWGEGVGAILVEPLSEARRHGHPVLAVIRGT
ATNQDGASNGLSAPNGLAQRRVIRQALATAGLTARDVDAVEAHGTGTTLGDPIEAEALLD
TYGQGRSARSPLWLGSLKSNIGHTAAAAGVAGVIKMVMAMDRGVLPPTLHVDEPTSHVDW
SSGAVELLTEARPWPDTGRARRAGVSAFGISGTNAHVVLEQAPDGTDESEPAPRSPRPAV
TLPTVPWVLSGRTAKALREQADRLRRFVGERPGLRSVDVARSLAVRTGLEHRAVVLGRDR
DDALTALSLLASEEAAPHLVSGASRTRRRVAFVFSGRPGAPGGPGRELYSRVPDFASAVD
EAGAAFAAHPDQPSAKAWGELWSGDGEAPADPVLARAALFAGQVAYFRLLEQWGVTPGHL
LGDVAGEPAAAHCAGVLSLADAAALVVALGRESRTGAEGPDGEPGEAVRLTVKELTFHPP
AVPLLSGRTGRPVSPEELRSPEYWVRPADEAAAPTDGMRWLTAEGVRDFLRIGPDGDRYD
LAGDGSEDDDVVLVPDPDDKGSEADALLGALARLHVRGVAVNWERILTDCGAQTVELPTY
AFQHQRYWPELSGLAGAARSHGESDPTRAERGREFRRRLAGAAEEERADLVATLVRGHVA
AVLRLGDGDSVDDGTPLPELGFDSLTAVDLRNRIGADIGFRLAPGLVFQHPTVTALTRHL
VDRWATAGTSDAADAEPDDTTAARSTLGPLFARASAQGRADEFQELVRRVADFRTTFDTP
EEGFRVPHVRLSRGTATARLVCFPTFAGGSGAHQYARLAAASRGERDVWALPAPGFTWQE
PLPASVDALARLQADGVEQCAEGNPVVLLGYSAGGWIAHATAAVLEERGAGPAAVVLLDS
HWPGSAMLPHLHAEIDRARAAGSTGALWTEESGDDAHFTAMAHYARLFQDWDPEGISAPT
LLVRASEPPFEQAPDDWQPHWDLPHTTADTAGTHFSIIREHSESALRSVHDWLNGLHR
>A0A445NG30|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces netropsis|TrEMBL
MMELHEGGDRPLHQRLATAGEAERHRLLMDLIRTHVSTAANGTGPVSLDAHRAFGEQGIR
GRAAAALRERLCEETGIALPATVVFDYPTPHALAGHISGLLAGGGAAPEPTTGPGGAAVD
EPIAIVGMGCRLPGGVRSPDDLWELVRSETDAISEFPEDRGWDVEYHPDPDHLGTTVTRH
AGFLYDAADFDADFFAISPGEAVTIDPQHRLLLETAWEAIEGARLDPTTLRGSRTGVFVG
LMYSEYGARIRQVPPSAEGYRVVGSMPSVASGRLAYTFGFEGPAVTVDTACSSSLVAIHL
AAESLRKGECTLALAGGATVMSTPWGYVEFSRQRGLAPDGRARSFSADAAGSSWSEGVGV
LALERLSDARRNGHRVLAVLRGSAVNQDGASNGLTAPNGPAQQQVIRQALANAGLSTADV
DVVDAHGAGTRLGDPIEAQALLATYGRDRPADRPLWLGSLKSNIGHTQAAAGVSGVIKMV
MALRHGTLPRSLHISEPTPMVDWSSGAVRLLTEARPWPETDRPRRAGVSSFGVGGTNSHF
ILEQAEPEAEPPRAALPASDEDGDGRPLPWLVSGRGPAGLRAQARRIHDFLKAHPETPDA
DVAYSLATTRAALPDRAVVVAGDRTEAMARLAGLADGEPGDADAHVASGSAAARDRLAFV
FPGQGSQWPGMAAELMNTSRVFRESIEACADSLAPHTDWSLTKALQGKSGAPSLDRVDVV
QPALFAVMVSLAALWRSFGVEPSAVIGHSQGEMAAAHVAGALSLDDAARIVAVRSRAIRV
LSGRGGMVSVAAPVDQVLRSIEPWGGAVSVAAVNGPRSVVISGDPVALEEAMAAFTADGV
RTRRIPVDYASHSAQVEEIRETLLTELAGIRPRQASVPFYSTVSGEPIDTTVLDAEYWVT
NLRETVQFDRTVRRLLADGHTGFAEMSPHPVLTVGIQETADDVEADGVLTLESLRRNEGG
TARLLTAVGEAHVHGIAVDWSQAFDHADPRPVDLPTYAFQRRRYWLEDAAPPQADMAAAG
LDGVDHPLLGAAVPLADGTGGMLFTGSLSARSHPWLADHGVADVLVVPGTALVELALHAG
ALTGCETLEELVLQAPLILPEQGTVRVQLSLGGPDASGRRAVTLHSRASDAGVDEPWTLH
ADGTLAPGEPAADDLPRSWPPTGAEEVELDDCYRRLAKSGLHYGGAFQGLKRCWRLDEDI
YVEVELPESGGDATPYGLHPALFDAALHAAAFVGLPSAAPDDAVTRLPFSWSGVALHAAG
ADRLRARIRFTGPDSLSVTATDPTGRPVLTVGTLGMRPVTAEALHRAAASAGTSLLRLEW
RPTTRPEPRATDTTRWAWIGTEAADAERALAPRGIRHEQHTALATLRAGLDAGGDAPDVV
VLAQPATARDTDLATAAHQAVHRVLAAVQEWLADDRLAGSRLVVLTRGAVAPTPGSVPDP
ALAAVWGLVASAQSENPDRITLVDLDAHEASLPALPLAVDSGEARIAVRDGSFLTPQLAR
VAPAAAHGAPLWRADGTVLVTGGLGVLGRMLVRHVVVSHGVRHLVAVSRSGASGEGVASF
VDELRAEGAELRIVTGDAADRAVLEGALATMEAEHPLTAVVHMAGVLDDGVLGSLTPERV
DRVLRPKVDAAWHLHELTAGSDVPLFVFSSVSSVLGTAGQGGYAAANAFVDALVEHRRGA
GSPGVSMGWGLWEAKSGLTGTLGETDMRRIARSGVRPLSDDQGLALFDLARATDAPVVFP
LHLDTAALGSGDTENIPPLLRGLARTPVRRATVRTEDEPGGDDLAARLARLPEAEQDAQL
LTLVRGHVAAVLGYDDPRTVGERRAFVEIGFDSLRALQLRNRLNSATGLRLPATLVFDHP
TPDALRGHLRTLLLPDAPSARDTGRGTVADAVAADPGPEPGRGDEAIEQLRSAASLEEVF
DFIDDQLGE
>B8MF01|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MSSIYQLYVFGDLNNDFDSSLRALCKSQGNPLLVSFLDRAAFALRAEIGALPLAQRSVFP
SFTTLPELLAKLQSDSVPHPALETALVCVLQFASFIKYISQAGQLYPTNANERLTGLCTG
LLTAVTVSCCRSLSELIPLAVHTVIIALHTGFLVNAVRLRIELSGNASDSWSMVIPGLKE
DPAIAVLEKFSSEMGIPVASRPYISASSHSGVTLSGPPQTLSHLLASDYLPTRTSLQTRI
RGPYHAPHLYDETDVEDILQTVSNGSWGTLCNHITVQTSCACNAAGEANFASLMRVALRE
ILLEPLRIDMLSNGVASEIAATGTAKCTLLPVGTLASSAFITALKNAGTSKVDVDNSMKG
LSIPEISIASDSGVFGQSKLAIVGYSGRFPDANSNNAFWELLCEGRDVARVTPKQRWNVA
THVDPTLKKKNTSGTLYGCWLKDPGHFDARFFGMSPREAPQVDPAQRLSLMTVYEAMENA
GMVPDATPSTRRDRVGVFVGSISNDWGETNSSQDIDTYYIPGSCRAFIPGRQNYYYKFSG
PSYSIDTACSSSLAAMHVACNAIWRGDIDTAICGGTNVMSNPDITAGLDRGYFLSRTGNC
KTFDDDADGYCRGEGVVSMVVKRLEDAIADNDPICALILNAYTNHSAEAESITRPHVGAQ
KAIFERVLTSSAVDPSAVSYIEMHGTGTQAGDAREMESVLSTFANKTTPGEGRETPIHLG
SVKANVGHGESVSGIIALTKILMMMEKNEIPPHCGIKTKINHKFPQNLAERKVFIADKPT
PWPRPEGQSRLAMVNNFSAAGGNSCVLVEDAPRSTKKVPEDLRSTHIVAVSAKTKTALLA
NIKSLVSYIEKEAPFLPSLSYTTTARRVHHPHRATAIGNNLDDILAQFKTTLSASAEPVR
PKATSVVFAFTGQGSQYPGMAHELLQFKSFRADIEHFDRIAQRQGFPSFLPVIMATTGEI
SDFSPIVVQLAATCSQMALAKLWRSWGAEPVAVVGHSLGEYAALNVAGILSDVDTIYLVG
KRAELLQTKCVQGTHGMIAVSASLEEIAAHVAGNQIEFACINAPTEIVLSGTTIAIDEAV
EALSQAEIKKMTRLRVPYAFHSSQIDTIMDEFEAAATTVRFEKPQVPLMSPLLSQVIDTA
GIVDAKYLARHARDTVNLCGALQAAKAMKLVSNASSFIEVGPHPVIVGLLKSNLGPVMVL
PTLQRKMDAWRVLTRSLSTLYESGYTIQWGEYHHDFQQSLGVLRLPNYNWDLENYWIQYE
NDWSLFKGDAAFLTGAKPALSTTCVHRIVEEKHGIHEIVVVGESNLLREDLDSFVRGHKI
NGVALCTPSVYAEMALVLGDYIRKSEPKWANCLVDVQHMDVQKPLAVKTVVGEPQPLRCR
VAFDTATSKAAVQFYSVTPEGKTLTKHAECSVSFPVATEALAETQKSAGDILTRMISLRR
SIADNDRVQKMAGSTGYQLVSSLASYAPEYKGVTEVVIDSNTFEAVAKIKCNKAPTTGVY
KVNPYLIDNFGQPALFIMNANDQVDLDKDVFVNHGWTSLHFYKEVSLQNVYHSYVKMTGP
NEEGMYSGDMTIFDLEGGEVVACYRGIKAQKVPRRLMDYIVRMRDDTRVEPPVSTNKSGP
AGIEAHITEPLVIIAERNTSSVNTSSWPAALKIISEESGVPVTQLTKEKTFADLGVDSLL
SLLCASRFREELSLHCESMIFEQYPTVGELQAEWETGSSLADPSAVTGRDAILNSMFYDE
GVQDDVFTAKKSSEKGSGYSSQTDPTGKSSPATEIVSLDLNPSTKVSSLLIQGNPTSPVT
TKTLFLLPDGSGSASSYGSLPTVDKSVAVVALNCPYMKEPSSYPLGIDHVADLYITEIQR
RQPHGPYVLGGWSVGGIFAYHCAQLLAAQGEVVSDLFLLDCPVPQGLDHLPRRYFEYCDE
IGLLGVVHSRHGERRAPPPWLIPHFTACINSLHDYYASPFVPASRAPKTHVIWACNSIDA
DIEQKFEHRDDDPKGLKFLTTARKDFGPCGWETLLPVARMSFSRVEGANHFTMMKGPGAE
ALSRIIKNALV
>B8LX28|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MGDRNSSDIMRPSAAFFCPQNKPPKPSYLDLIRRYLRNNATLQPFRAAILDSLFTTWKIL
GEANPGIAALTQGPRYIQHFHDWIAATESPLTSNELQWTEIMSGIISLPLLTVMQIVQYF
QYLETRQINHEQFVQEIRIGGAQGYCGGLLPAAAIAASRNEEEVVKNACIALRLALAIGA
YGELGDDENITGPTTVVLRTKYSEQAEEIVSRFPGTYVSAITDPETISIVGPVNVVEELR
VYAEGQGIKSTKLHLRGKVHNPENEDLCKELSSLCQKHADLLMLPTTASLQCSLRSNKTG
KELSNGDVTAFLSEEVQESTLASKCEWYNLLNGIAEDLDKASKTEKEHTFALFGTGRKNC
VPTTPFEEKNIRISKLDVMIYVEKLEIPRDGRTLNQYPENAIAIVGAGCRLPGANSIDEL
WEILSSGASRVEKLRASRFDLSTISRGTVGPDAKEVNKHELYGNFIDDVESFDSNFFGIS
PREAMYMDPQQRLLLETAYEALDGSGYLRNHRREDFDNVGCFIGASYTEYLENTSSYNPT
AYTATGTIRAFQSGRISYHFGWSGPSEVIDTACSASLVAVNRACKAIQSGECPMALAGGV
NIITGVNNYFDLGKAGFLSATGQCKPFDEAADGYCRADGVGLVALKSLRQAMADENDVLG
VIMGVGTNQGGLSPAITVPYYRAQIRLFKNVLQQSGLKSEQISYIEAHGTGTQVGDPIEI
SSVREVFGNPERTEFVNLGSLKANVGHSETAAGIGSLMKVLAMLKNGKIPPLAGFKSLNP
KIPALEPDYLCIPTELQDWDVSFRVACVNSYGAAGSNSALICGEAPKVASMSSVSSTDQK
VLEVSHLQYPILLSGANNPSLKANAAKLASYIRSYSNAAQLSISDIAFTLYHRRKHHKVQ
WTGLAHDLESLCQSLDKIEQGIEVPVSPKAVVLAFSGQSKQTIGLNPSWYVSFPRLRYYI
DLCNDTIMRLGYSAIFPAVFATDPVEDVVALQCGTFAVQYACAKCWIDAKLDVKAAVGHS
FGELTAMAVTGVLSLEDALNLVATRASLMQRKWGAERGTMLAVEANLDTTRQIISAVSES
IEIACYNGQKSHVLVGTETDIGQVERFVATDNKYKGTRCTRVKTSHGFHSVFTEPLLQDL
DEVAQRLRFEGPSFPLESCIEKPICEGDQLIQPSRIVQHTRTPVYFGAAVSRLEERLGSC
IWLEAGSDSPIIPMIRRATQDPSKHTFLGLRTKDFARPIDVISQASMTLWQEGISASCFE
GFYSSMSEGITLDIFKHIWLPPYQFQRTRHWLQYMDAVTEERRAFDEKLHSISRVGSLTN
QTPMPSQKLVTARSRDSTSWSSLEFVIHSETSRFTDIVSAHAVRDQPLCPASMYMECVVM
AAQMAEPSISVKSLSFQNLSFQGALGINYNRDVSLLLEGDGEYLAWNFTVGSTVKDSKGR
LTTHAKGKFSVTSHIDFQVYERMLADRMNEILVHPQSERLMAGRAYTLFSRVVNYAETLR
GISEITILNNRHAVAEVCRPKVSVSSSESTAVSVCDTVTLDTFIQVVGLLINSSETCPVD
EVFIATGIDNIIMQDCDFTNLQHDTWKVYAMATTRSESHVAGDMFVFTKDGKLIFTGSGV
QFSRFPISKLEKVLEGIGMNNGSKSPISNNNIGRGLPSPPASPVHVHMNEDFKTIKDRHG
LRVSTTVDTDEQTLVGQYSVSRRPSALKSAMVKNDSRFGTLGLDSMSKLEFVNQLRAQLG
DEISPTQDLSQVADLYNKLFAHNSTTNTKSVHIDHVHEIELDVPLSPTAVNSPATAGDSQ
SKLRIRQRILELITENSGESVTNIKDEVSLQDIGIDSLSVIELKESFEDVFGLQFGDWDF
GLHLTVRELLDYVVVSGNV
>A0A8F8UF06|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nonomuraea coxensis DSM 45129|TrEMBL
MRTEDKLRDYLRRATVELSETRRRLAEEEGRRHEPVAIVGMACRFPGGVGSPEDLWELVT
AGVDAIGEFPEDRGWDVEDLYDPDPGAAGKSYTRHGGFLHDAADFDAAFFGVSPRNALAT
DPQHRLFLQTCWEALERAEIEPGTLRGSRTGVYAGNMYDYYSTRFLAGAPESVEGTLFTS
SAPSVMSGRVSYTLGLEGPSLTVDTACSSSLVALHLAVQALRRGECPLALAGGVTVMSSP
VPFVEFSRQRALAPDGRCKSFSASADGAAWAEGVGVLVLERLSDARRNNRRILAVVRGTA
VNQDGASNGMTAPSGPAQERVIRQALADALLDTRDVDVVEAHGTGTTLGDPIEAQALLAT
YGRGRPADRPLWLGSVKSNLGHTQAAAGVAGVIKMVMALRHGVLPRTLHVTEPTPHVDWS
AGGVRLLTESVELAGRARAGVSSFGVSGTNAHVIVESAPEVEVEAVVGEPLVSDGPVLVW
VVSGRSGPALRAQAARLREYAASVAEEELAGAGRALARRARFPHRAVVVAAGREELLAAL
DAVAEGRAHACVISGVAPGVGSAVLVFPGQGSQWAGMAVELAGSCAVFAAALERCDRVLV
PLTGWSAGGVLRGEAGAPELVGSAVVQPVLWAVMVSLAEVWAAAGVVPQVVVGQSQGEIA
AACVAGALSLEDAARVVVVRSRALERVAGSGGMAALDVPASRAEELLASGWGGRLWVAVE
SGPSGCVVAGDAAALEELAALAEAASPNGTASPNGTASLAGAAAPSGTAGLAGVRVRRIA
VDYASHTPHMRALEGELEAALERVGSGPGRVGFCSSVTGGLVAGEELSGRYWVENLCRRV
RFDAAVRVAAGSVRWPVFVEVSPHPVLVGDVGEICGDAGVAAGVCGSLRRGEGGPARLLV
SLAQAWVQGAPVEWAAVLGGGPRPRTQPPTYAFQNSRFWLGDGIASGGRPRGEGLDGSRH
PLLDTVVSTADDRYVLTGRLARRTAPWLADHAVRGGVLLPGAAFADLALEAAAHAGCDRL
DELVIETPLYLSGGTVTLQVTVGPPEAGRRPVEIFSRPADGDAWQRHASGVLAEDPSPAA
PYAWAAAWPPPGATLIDLADGYGRLAGQGYEYGPAFQGLRALWRSGDDLYAEVATPDGLD
VTGFGIHPALLDAAFHPLVLARGDDELRLPFAFTGVRLYAAQADALRVRLSAAGQDATVE
AADSSGAPVLAIEALRTRATAAPAAVPVPYGVDWTETALPPAAGPEPVVITCVSDDPDPA
AAARDLTARVLDAIAIHPDDGPLAFVTRPGDPAGAAVRGLVGAAHAEQPGRFTLVETEDG
DTAWGRLAATGEPWIRVRDGRYWVPRLTRRDPAPTTPESAPHGTVLVTGGTGGLGALVAR
HLVERHGVRDLILLSRSGPGAPGAAELTAELEKLGAHVTVTACDVADREALRAVLDAAPG
LSGVVHAAGVLDDALVQDLTPDRIASVLAPKADAAWHLHELTSDRPLSMFVLFSSVAGVL
GNAGQGNYAAANAFLDALAEHRHALGLPAVSVAWGLWDTASAMTGTLGQADLARLARAGI
APLTADQGLALFDAALTTPDPLMVAARWNTAGLRSRAANGDLPPLLKGLVRVPRQMATPG
AAAQAGLAGRLAALPRKEALRVLTETVQAHVAAVLAHVSADSVDVDRPFNELGFDSLTAV
ELRNRLNADTGLRLPATLVFDHPTVTSLAAHLSETLTPPDTPPRTPAPPEDGLRAALDHL
DQVLEHANGEAAAIRERVVPLLQNALVKLGSALATAGGVLDKIDSASDEEIFALIDNEL
>A0A8F8UET9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nonomuraea coxensis DSM 45129|TrEMBL
MAGESTQRAVQDEPVAVAVVGMACRLPRAADPGRFWRLLKDGVDAVTEAPEGRREPGAAY
PRGGFLDDVDGFDAAFFGISPNEAAVMDPHQRLALELAWEALESARAVPATLRGSAAAVF
LGAISNDYAALQDRLGLGGLGRHAYTGANRAMIANRVSYVLGLRGPSLTLDTGQSSSLVA
VWMAAESLRRGESDLALAGGVNLNLLPETTTAIGNFGALSPDGRCHVFDERANGYVRGEG
GALVVLRRLADALADGDPVHAVILGGAVNNDGGGDGLTVPSARAQQEVIALACDRAGVRP
GQVRYVELHGTGTKVGDPVEAAALGAAYGTSRPAGDPLLVGSVKTNIGHLEGAAGIAGLL
KVVLALKHRELPPSLHFTTPPAEIPLDDLRLDVVRTLRPWPGDAAPVVAGVSSFGMGGTN
CHLLLTGPPPSSEPPSSEPPASSGVGGGAGAPWAVSARADEALREQAGRLVATAADPATD
PGDVALSLAATRSAFERRAVVLAQDRDTRQAALRALAEGRAHDDLVTGTATGDGRTAFVF
PGQGSQWPGMARDLLSASPVFAARVAECADALAPFTGFSLLEVLSERPGAPGLDRVDVVQ
PALWAVMVGLAELWRAHGVEPAVVVGHSQGEIAAAAVAGALSLPDAARVVALRSRAIAGI
AGRGGMMSVAAPLSVVEEAAAGLAVHVAAVNGPRAVVTSGPHDALAALAARLDGHPTKII
PVNYASHSPEVEQVRDEVLAALAPIRPMSCATTFVSTLTGEPMDTAGLDAGYWYRSLRHP
VRFAEAVGTALGARCELFVECSPHPVLVAGVEETAEAAGGDVTAIGTLRRDDGGPGRVAR
SLAHAYVSGAPVDWAGLCPGARLVDLPTYPFQRRRHTPRSLPRPRQGVEPPVTAEPEAVA
SPGRSREDLRRLVLDSTARLLGYADAAEVPPGRTFKDLGLESAAAVELRDRLRAATGLRL
PTGLLFDHPTPERLTDHLHTRLTALDGPAGTEEEPAKGAASAEEPAATVGDLATDDDRIA
VIGIGCRYPGQVSSPEDLWRLVMTGTDAIGDFPANRGWDLDALLAAGPDRAGTSDTRHGG
FVHDADLFDAAFFGISPREAAAMDPQQRLLLEICWEALERAGIDPAELRGSPTGVYVGAM
APDYGPRLHQPTGAADGHLLTGTALSVVSGRVAYTLGLRGPAITTDTACSSSLVSIVLAT
QALRRGECSMALAGGVTVMANPGMFVEFSRQGGLAADGRCKAFSAGADGTGWAEGAGVLL
LERLSDARRRNHPVLAVIRGGAINQDGASNGLTAPSGQAQQEVIRDALADARLSAADVDA
VEAHGTGTRLGDPIEAEAVIAAYGRERPADRPLWLGSLKSNLGHTQAAAGVAGVIKMVMA
LRHGVLPRTLHVTEPTPHVDWSAGGVRLLTESVELVGRARAGVSSFGVSGTNAHVIVESA
PEVEVEAVVGEPLVSGGPVLVWVVSGRSGPALRAQAARLREYAASVAEEELGAAGRELAR
RARLAHRAVVVASGRDELLAGLEAVAAARPHPSVLTGVAPGETGPVLVFPGQGSQWAGMA
VELAGSCAVFAAALERCDRVLVPLTGWSAGGVLRGEAGAPELVGSAVVQPVLWAVMVSLA
EVWAAAGVVPQVVVGQSQGEIAAACVAGALSLEDAARVVVVRSRALERVAGSGGMAALDV
PASRAEELLASGWGGRLWVAVESGPSGCVVAGEAAALEELAGSAVFDGVRVRRIAVDYAS
HTPHMRALEGELDAALERVGSGPGRVGFCSSVTGGLVAGEELSGRYWVDNLCRRVRFDAA
VRVAAGSVRWPVFVEVSPHPVLVGDVGEICGDAGVAAGVCGSLRRGEGGPGRLLVSLAQA
WVQGAPVEWAAVLGGGPRPRTQPPTYAFQRSRHWLDADAASSRHPLLDQAVPLAVDGGFL
LTGRLSLAATPWLADHAVDGVVLLPGTAFAELALEAASRTGCDLVEDLTLEAPLVLPATG
ATHLQVTVGGPDEHGRRPLGVHARRTDDDPWTRHAHGLLATAPATAQERERLTSWPPEGA
ELDPDDLYERLAARGYGYGPAFRGLRAAWRGADGAAYAEVALPEPARADAARFTLHPALL
DAALHLAVGEADATDDALLLPFSWSGVRVAALGAEELRVRLDDRGEDRIALALFDGTGEW
IAGIDTLALRRTARNAARPAASTPAYAVEWAEAPAPAAPAQRWAVVGYDELADEIEAEMP
ASGVTAPRYYDLASLADMTAGETPGLVLAPLRGDQDDLPYAAHDGLGQALDLVQGWLGDE
RFAGSRLVLVTRPGDLAGAAVRGLVRSAQSEQPGRFALAELPEGFSAWERLAAAVAAGES
QLAAPDGTLRAPRLARRDATDEAVPELTGTVLVTGGTGGLGALVARHLVERHGVRDLILL
SRSGPGAPGAAELTAELEKLGAHVTVTACDVADREALRAVLDAAPGLSGVVHAAGVLDDA
LVQDLTPDRIASVLAPKGDAAWHLHELTSDRPLSMFVLFSSVAGVLGNAGQGNYAAANAF
LDALAEHRHALGLPAVSVAWGLWDTASAMTGTLDQADLARLARAGIAPLTADQGLALFDA
ALTTPDPLMVAARWDNAGLRARAERGDLPPVLTGLVRAPRRAAPQARTAPAATAGPGPTE
LLAGMTEADGRAHLTQLVRGHVAAVLAHSSPDQVEVDRVFNELGFDSLTAVELRNRLGAD
TGLRLPATLVFDHPTVTSLADYLFQSLAPDGPSPEDALRAAVDQAEAALLAANGQADAVR
RSLVAILRSALTRLGAGQEAGRPGSGGAAEEIVSASDEEIFALIDNRSMTSPLRTSVEGP
GHGQ
>A0A3S4RK94|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium chitae|TrEMBL
MGSAEYQAEQAPPRFAIIGYAARLPGARDAAEYWDLLSEGREAISEVPADRWNADEFFDP
EPGAPGKVVTRRAGFVDDPTGFDAPFFGMSTREVRLLDPQHRLLLETAWHAVEHSGTAPT
ALADTNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISHRLGLQGPAVA
VDTACSSSLVAIHQACQALRLGECDLALAGGANVLLTPATMITFSSAHMLAPDGRCKTFD
AAADGYVRGEGCGVVVIKRFEDALRDGDHIRAVIRGSAVNQDGASGGLTVPNGVAQQRVI
ADALHRAGLTPSDVGYLEAHGTGTSLGDPIEAQAAGAALGAGRDPGKPLLIGSAKTNIGH
LEAAAGIAGVIKVVLALEHETLPKHLNFENPSPHIPWDSLPVQVVRESTPWQRNGVRRVA
GVSSFGFAGTNAHVILEEAPAPAEPGPTVIDAPARFSVLPLSARTPAALVQIAEQYRGWL
REHPEATLADLCRTAGTARAHLEHRAALVVNTRDAAIELLGALADDRPAPGLVRGESHEA
PKTAWLFTGQGSQYPGMARELFDTEPVFAETLRACADAVADALEKPLLDVIFAMDGPDSE
ETLRQTSYAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVLTLTDGALLM
AERGRLFGSLPAGGRMVAVFTAAERAEALTDEYPSLSVAAYNGANTVLSGPTADLEKAVA
ALTADGVRCDWLDTSHAFHSSLLDPILDEFEAYAQQFTFAAPQRILIDNRTGTALGRSVR
LDGAYWRRHARQPVEFAKSVRTLAELNCKTLLEIGPRPILTAAALAAWPEPATAPRALAS
LRRNASDHRQIIEAVADAYVLGHLPDFDALTAAAGRKLDLPTYPFEHRQYWYSDNRDARE
QADREPPAMRTETLGLLEDGRIEELAALLDDGDQRTREVLRKLAAHHNQQRATQSVAEDR
YEIHWEKTDLGVGDGLGDGGDPAPWLLIGEDNAATRPLLDLLTARGRQHRLVGLPATDAE
EAALAEQLRAAVAEGAAPRILQIAALDADPDPGTGLSTRALLRMQHRILGGTRRLFAAAV
AAELRGPIWLVTRGAQHVLDADVVAPEQSCLWGFGRAASLEYPQLWGGLADLSSDPDAEW
PRLLAAVSAPRDTDLSEDQIALRGPASYVRRLVRRSAAPTDAPTELRSDATYLVTGGLGA
LGLEIAEYLAARGATQLVLTSRREPAEAVAQRIDALRDQHGCAVRVVTADVADAHDVARL
LALVSAELPPLAGLVHAAGEIDTTPLSSLSDDDVDRVFAGKVWGAAQLSEATADLDLDFF
VCTSSIASVWGGFGQTAYGAANAFLDGLAWRLRAQGVAGVSVNFGPWSTGMADAESRSRL
EARGIRTLSPTDALAGLADVLVAATDGPAQGVVARVDWARFLPLYQQAGRRGFLAELERE
VPAAVTAAAPAGSAAGTTQLVDRLTAAPVQQRKKLLTDYLRDAVAEVTRVDTSEIREDAG
FFDLGMDSLMAVELRRRIEQGVGQQIPITLVMDHPRLSDVADYLLGDVLGLAQQAAPVAA
PTAAATRRDEPIAIVAVSCRFPGAPNPEAFWDVLAEGIDAIREVPEDRFDIDEFYDPDPD
APGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLILETVWEGLERAGYAPAALR
GSRTGIFTGVAANEYAHLLSAEPIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTA
CSSALVAVHQAVQALHAGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASAD
GYVRSEGCGILVLKRLSDAQRDGDRICAVIGSSVVNQDGASSGLTVPNGGAQQRLIESAL
ARAGLSGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGGAREADRPLLMGSVKTNIGHTESA
SGAAGLIKVVLALKNGLLPRSLHFDNPSPHIPWDSLPVQVVRESTPWQANGRPRRAGVSS
FGFTGTNAHVLLEEAPAPAEAPVPDTDAPAVHVLPLSARSPEALVSLAQRYDAWLTDNPD
ADLADLARTAGTGRSHFEHRAALVVDSVDSARHALADLAENRTRPGVVRGEHTRPPTTAW
LFTGQGSQYPGMARELFDAEPVFADTVRRCAEAVEPMLPVPLLDVLFAADRETGEQLRHT
SYAQPALFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFTLEDGARLMAERGRM
FGSLPEGGRMVAVFADAKHVEQIAGEFPRISVAAYNGPNTVLSGPGADLEQIVERFAEEG
IRCTWLETSHAFHSELLDPVLDEFEAYAAQFEFAVPTLPLVCNRTGAVLTAHSPLDAPYW
RRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHLAAPRAVASLRKGVG
DRRQIADALAAAYAGGHRPDFAALHRQPRRVLELPTYPFQRRRFWPKTAGITVDGPAVSG
ILGSGKDLASGDTVYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAAAGTPARTKDV
FFYEPIILPEKSSREVQLTLHPLDGGEGSTFQVHSRPYGERGADWSLNAEGTVVPGVDPD
AEAPDGKDPKADDPVDEAIERLDRMRPQDLFETFADMELAWGPTWSGSLKSLWLGEGEAI
GDILVGEELAAELGAEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVMLRE
KMPRRFYCRAKWHTSALDAETQVFDLDFLDRDGRQLGGIREFTVKRAPREALLRGLGGDA
TRLLYTVGWHEVPAPAPAESPAGGNWLICGFDELADKVPGCVPADRITDPALLGEQLSAA
HERGMAFSGVVWRAAPAPAGEASTDAAARLESEIANLLSAVHTVQGGLKLPGGLWMVTER
AVATESGEPVDPVQAALWGLGRTTVNEEPALRARLVDCDGSPEAVGVLAKLLAAGPALEE
PELALRQGKLLASRLLPWARSGHLTVPRSPDYALAPTERGAIDNLRLVEADVPAPQDGYV
QVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGVVTQVGDGVDGLEVGQRVYGFMQGAF
ASRFNVPAQLLAPIPDGVSAVEAATIPAAALTVRLAFDWAQLKPGDKVLIHAASGGVGLA
AVQMAQQCGATVFATASTFKRATLRNLGVKYVYDSRSTDFADLILADTDGAGVDVVLNSL
TNEGFLEATVRATALNGRFAEIAKRDIWTPEQMAEVRPDIAYEIVALDTVTFQEPERIRS
LLTEVSQGLAEGQWRPLPAEIYPLAEARAAFRRMQQARHIGKIVVQMPKPLQPQGDRSYL
ITGGLGAIGLHTAAYLAQLGAGDIVLTSRRAPDPDAQQVIDDIAERYKCRVHVFTADVGD
EAEVAKLLDRIRAELPPLAGVAHLAGVLDDALLSQQSVERFRTTLTPKAFGADHLDRLTA
DDALDFFIVSSSVSSLFGSPGQANYATANALLDGLIAQRRARGLPATGVNFGPWAQGGMA
SSEAATANISAQGLIPLEPSAALSALAEAMANGTGQATVIKANWQRAAKVLGASRPPILD
LVLPSAAGEVTGDSELFKQLQEIPVPQRAGFVTEFLQREVQNFLRLAQPPAASSRFLDLG
TDSLMAIELRNRLHSQFGGAFTINATAVFDYPTIGGLAEYLVGQLPDAEAEAAPVAEPEP
AAE
>A0A378JVZ3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Legionella busanensis|TrEMBL
MRSILEIFQERKRTDSLKTIFTIIKNEHEFINITYSKLYENSLKIAAFLSRQKNGSHSSL
LLIPPGEEYIYAIFGCLLAGVIAVPAYPPTNNKKIDRLKYILNNAGSNNVITLKRLADDV
SSIAPNVNSIEDMLAVDSIGFIPKKVTPEDIAFLQYTSASTGDPKGVIVTHQNLIANSNS
IQKSLKSTYKDLFGSWLPPYHDMGLIGCIIYPFIVNMTSILMVPTFFIKKPYQWLKVISD
LKITISPSPNFAYELWTRTVKEEQKKALDLQHWRIALNGAEPINATTLERFAQAFAVCGF
NRKALFPAYGLAEATLMVTGKIENEPLVSCLVDKKALRNNKIEFTKNESDSTCLISSGQF
NQGFDIKIINPKTLVSLKPYQIGEIICAGLSVTQGYWQASKLNEQLFCSPKPNLENKSYL
RTGDLGFIDDKSNLYVTGRIKDIIIIYGRNYYPQDIELSIVNSHSALSINSNIAFAQNEA
GQDRLIIVQEVPRHTKEFSGLFDEIINICIVEHDILPDRIVLIKKGSLPKTSSGKVQRNA
CRQQLAAGLLPIISEWKSVSYNEISNNNTSSPAVFSQKDSNQSVSNWIKTWLANYLNLSI
EQIDPNKNFAYYGLNSVIAMEFCTALQTSLNYDFNPALLWQYSTVNLLANYLIDPQKQSS
ILKPLPIEDLSLEPIAIVGIGCRFPGDVNSPEEYWNLLCNGSDGITEVPAERWSVDDYSG
SPNTTSKIASSRGGFIKHIKEFDAMLFNISPREAEVMDPQHRILLEVTWEALERANIEPL
SISNSNCAVLVGLGTNDFGYLIHDSSVAFHTNTYFNIGNSHSAASGRLAYFYNLHGPVMS
IDTACSSSLVAIYNAFQNLQNKKCDLAIAGGVNCILDPFISIGLSNANMLAPDGKCKVFD
EKADGYVRSEGCGIVILKRLGDAKKSGDNIIAVVKSIETNHDGFSNGMTAPNPKAQKEVI
EKTLASARLAPNDITYIEAHGTGTKLGDPIEFNALTEIFGSTERKKPLYIGSVKSNIGHL
ESAASMASFIKVALMLKNKKIPKNLHLNSVNPLINLQAIPAEIPQHLTDWEIENYNKRYA
GVCSFGFTGTNAHAILEEYIEENTKSIKNDNDDQIATSAFSPYLFTLSGQTKEALQAQIV
NYINYLKDNPDINLVELCQNLFNYRTHFQYRLALTATDIIDLENKLISGDYLTNLIPVNN
KNKIAFLFTGQGAQYTHMGKELYFSQPTFKHAIDECHEILKKDLPVSLLEILFEEKNKEL
LNQTQYTQPAIFTIDYALAKFWQSLGITPSAVIGHSVGEYAAAVIAEVMSLKDALKLVAL
RGKLMQSLPKGFMLALNGQYEDSLEIIHAIRQANPDLILDIAAFNSLEQIVVSGEQKAIK
KVEELCHEKAIQTTLLNVSHAFHSRLMIPILDEFQKCAENIIYHSPKMAFISNLTGLNLE
VKPSANYWREHILKPVKFSEGIKTLIDNNFNFFIETGPHPILTSFGIACHAEAGNRNWLG
SLKKNGDDWSPILNSLQKLYLSGVALDWKKLNKHLMNTLKKIHLPTYPFQRKLYWPETLT
KVLNSSQNKLYNAVYSLQWHEQEIASNNLTDKQLGVWLVFIPADYKIEQFSIAFQQRFEK
IIYIKPGNSFQNTNGKLFTINPNKLEDFDKLVADNSVISGIFYLWGLDLKNDDSESTSSE
DINNSIKITCDGLLNLVNTISKKSAPALSLWVVTHAALFPPHKSNLPIASPLIGLSKVIN
IEFPQLKYNYIDVVSPEIKIDEVVEILYKEVKANTYGQLIAYNHNKRYVPFISPYSLPTQ
ISSALFKPDYTYLITGGLGGLGFELCKWIISNGGKYIAIMGRRTLNAHLGRQLQELKDNA
VVNYYQTDVANLENLTQKMSELIQEMPSIKGIFHTAGVLQDCLITNHTWQRFKEVTDPKI
AGSWNLHRLSQKLNFALDYFVLFSSISALLGSRGQANYAAANAFLDGLSHYRHSLNLPAL
SINFGPWENIGMTHNHEQPWLKVGVKNIPIRNGLQIIGKMLTTNSPQLILLPYALEQKAV
KFLSTMQLALMNKLFELELNLKDLVLEPALDPLIEENLLAKIQKEMHVEEKNKIIVEFLI
KEVSKILNLTKKDYDLAESRLLELGMDSITGVELLNAINNAMPLNTLSIKALMFEDRTIK
ELAAYINELAATLN
>A0A1M9LJN5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus subsp. abscessus|TrEMBL
MDPQQRVAMRVAWKALENTGLNPGAVDGSEAGCFIGISPNEYGPPVGEVNAHSGMRVVGR
GQLGAAGRISHGLGLIGPSVCVDSACASSLAALHLAASAVRADECEWAIAGGVCVMGSPG
GFYEFSRMHALDPDGHCRSYSDEANGTLWGEAVGMVVLERESRARALGHRVYGRIMAVRT
NHNGGGKPILVPRGRAQAKLVAATIAASGVDPADVGMLEGHGTGTRAGDPLEILALQSTY
GAGGSNALLGSAKSNAGHAQSAAGMVGLIKLLLSGQHGHIPPTLFADNPTTKIDWSMTGI
RLATKLHPWEPKDGIRYGSVSSFGAGGANAHAIIAMPAMDAQGEDGDDF
>A0A8D9NPJ7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Burkholderia pseudomallei|TrEMBL
MAQVAFLFPGQGAFYAGATRALSGAYPVVQRAMQAIDAVSVRRLRRPLLATVWDGHIGAE
DLLQHAPDLLQLAIYATSVSYFEALRARGVRPDVLVGHSFGEIAALTCAGAFSIETGAEI
VCDRIDALRAAAPADGRMAAVGASPDAVRAHLAACFRGAPDARAGRVRIAVENHVSQTVV
SGACEYVDEFRAYCARNNISAQVLNSPYAFHHEDLENARIEFGRRLKAYKNKALEYPVYS
PILNRYYTAADDLGACLARHLVLPVRFGDGVARLKAAGIGAFVECGALNALSRISVRALG
PGAVKTFPGASSAGGELAGLENVLAYFNGGSVMNDDIRASNLQLDFDEFWRNSGPGIVDK
IKGELKRFFDARGLQATPAPQIVADHGVAAGFAGGLTAGAADYAPKVAAGVSPAAAPVAA
PVVAAAPAAPLAVAPAAQAAAVPAASARVPRDRLFVELVAIYAEAMEYPVEVFTETVELE
AELGIDSVKQTEIIQRISARYGLPPLPANFRAGDFKAMGQIVDFVYEHQGEAALVTS
>A6LQ11|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052)|TrEMBL
MNLDILTLKSNKADDRTQIESISSKDIAIIGIAGKWPLANNVEEYWENIKNGKDCIQNFP
YSRKKDIEPFCEKNKEYFECGFLNEIDKFDYSFFHISPKDANLMDPHHRLFLESAYEAIE
DAGYGGKKIIGTNTGVFVGMSDLGDIQYIDLINKSEPEFLVQALSSNTKAILPSRVSYTF
DLHGPSMLIDTACSSSLVALSTACKSLRENECEMALVGGAKAYLLPLKERPMLGIESSDA
RTRAFDESSDGTGVGEGTMAVLLKPLHKALKDRDHIYGVIKGIAINQDGRSIGISAPNPV
AQADVIEKAWKDARIDPTTINYIEAHGTGTKLGDPIEIDGLTKAFSKYTDLKSFCAISTV
KSNIGHLYDLSGLSSLIKVIMEFKYKELAPSIHFNVPNQRIDFERSPVYVNDKLRKWEAV
DSVRRCGISSFGFSGTNCHVVLEEAPKTVNSICPAKSTEVLAVSAKSQEVLIELLKSYLG
YLEKDKTINFHDFCYTANTGRGQYECRVVFLPKDQAELIDLLKNCIKKQPLDDEQTKKLK
KIFFGSYNLLSGKNVSKSGNYISNNEKLQFSEEANSKLKYYNTVKKEDISILQSVCDLYI
KGGDVNWDELYRGEKRSRVSIPVYPLKRERCWLDMPNKKYNVGMSNINGLLEVENLPDEA
RKKIAMILKEYEINEKQDESIDEHLKVVLAGREDGMYTETEKILAKIWYKVLGANKINIF
DDYLELGGDSISGAKIVNLVNSKMNKNIAITNLMENRSIIDFAQYIDSELSESSLPDILP
IEEKQYFPVSSSQKRIFITSLMSKNVYNVPGVLILEGKIDFNKFKDTLKRVADRHEILRT
TFDYKEKKIVQLVHEEAVISLEWHEVKENNIDEIIKSFIKPFDLKQLPLFRFHILKVDEQ
RHYLFYDFHHIITDGTSHGVFLNDFIHLYSNLPLPEITIQYKDYAFWQNKILNENHLKKQ
EKFWLKRFSKQNTLLQLHYDYTRPDIRSYKGKNSFFTINKDLKSRLKQFAYENNCTLFVP
LLSAYSILLSKNSGQDKIVIGTPVAGRQNKKLENLVGVFINSVAIVTKPKAGYLLADFVK
KINKEVLKVFKNQEYPFDILVEKLGWHNNPSRNPLFDTMFQYQNMVMPKMNCTEVKVDRY
EIENEIALFDLTLEIIEHDSVLNCRFKYCRDLFKSETIDRWREEYLEILNYIVENKELKL
EQLVSDKHDDSIGDLKLDCVEFNFD
>E1VID6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|gamma proteobacterium HdN1|TrEMBL
MSNNNNDTALLLKQALKELKKSKESIKRLEKEKIEPIAVIGMGCRFPGGVSNPDELWKLL
ENGADAITDMVDQRWSSDQVYDPNPEAVGKLYTKANGLVEDVDLFDAEFFGIAPVEARLM
EPQQRFLLETTWDALEHAAIAPDSLMGSKTGVYIGICHMGYSHMQAKYCGPEDVSPYDGT
GNAHSIASGRISYLLGLQGPSISVDTACSSSLVAIHLAVQSLRKGESDLALAGGVNLVLE
PTTSMIFARAGMLSPDGRCKTFDASANGYVRGEGCGVVVLKRLSDAVRDGDNVLAVVRGS
AVNQDGKSQGITAPNELAQEKVLRAALEDARLQPQDVTYVEAHGTGTPLGDPIELAALNT
VYGKLKDGKPREGKLMVGSIKTNMGHLEAAAGVAGFIKLVLAVKNQVIPKHLHFQKPNPY
IDWSTIAIDVPAEQQRWTAPHRVGGLSSFGFSGTNCHILVEQAPNVLEAGVLEAGVQDDR
QAVKPFAPKLLTISAKTKEALQAYLDVYSRALQMPALQSGRWEDLCFTAATGRHHFRNRA
SILASSATDAAEKIQALLGQGAADGVTVSDVGTATPKVAFMFTGQGAQFAGMGQALYAQF
PVFHDAMDHIAQLMAQYLELPLLSILWGDNAHLLDETQYTQPAIFALQYALTQLWTSLGV
QASCVTGHSIGEYAAAVYAGVMSVEDAVRLICARGRLMTSLCEKGSMAAVFASAAETRNV
IDSIDSVIDVAAVNGPRNCVISGERNTVVQAIALLADHKIKSKTLQVSHAFHSPMMQPML
DAFKREVEFIVLKAPRIRFVSSKTGKTATQDVKRVEYWVEHVRDAVLFLDAAREMGAQKI
NACLEIGPGANLVKLAPQCIETAAPVSFLHSVDREVNEAEHLTSVIAGLHNVGVAIQWQN
LFFGEKYVRLNLPTYPFQKQSYWVDEIRLGNYSKQSGMSFARMLYEAAWKELPLTTDEQH
REGKLFSFEDLVVIGSKPDWMDALQAQFSHILLLDGMSDADAIKSAVLPLQEKARANGKV
LPVLLTAPVMPSDLSVLPSVINAAVEPVLEAVRALVVGGDSTNPVRLWVVSEGAYGTAYG
IANINLSAWPLLGFAKGLALETGELWGGILDVSGTAGEQAAAILAELAGQAIEDVVKYEG
NVRSVQRLQADRPAQATLPSLDGKASYLVTGGLGGLGLYVAQALALSGAKNLVLMSRRGD
LQSLQGEPRDRVEALQKNGVNIRVVNVDVADASAVSNLIQRLANGECPLKGIVHCAGVND
IVLAQDMQRDQWRNVTRSKVQGGWNLHQASLSLPLDFFVMFSSIASVWGSGGMAHYAAAN
HFLDGLVDYRLALGLPAAAFNWGPWGGAGMATGDAAEEAARRGLRPFDPQSGIELLSKSW
TCGKAHQIMADVRWDRFREIMEMRRAHPFFGALGRTLSATTGVTGEKSAFFKSLYPLVPT
ERAEKIVGYLQGLLGRVVGKAEGETVDSEMPLMDLGIDSIMALEIKKQLEADTGQAMRAT
LIFDYPTINKIAEHFSVALYGEEDSVVEATGGNAFYGEPIAIVGIGCKMPMAPNGPGDFW
KLLANGECGINDAPSQRWDLDRYIDKNEAAPGKTYTLSAGLVDDIESFDGKLFGIAPREL
ESMEPQQRLVLEHAWTALENAGYSPAAMNGTRTGVFVGVGANEYIRACATGAREEDIMFI
PTGNALNVIAGRVAFNLGLQGPCMTVDTACSSSAVATHLACQSLRNGECEVALAGGVNTM
VMPETFVALSKAHMLSKEGRCKTFDESADGYVRGEGVGILVLKRLADAERDGDNIVALIR
GSAVNQDGRSSSLTAPNGPQQQAVIRAALANAGLKAEDIDWVETHGTATPLGDPIEVQSL
EAVYCGHRSAENPLIISSVKTNIGHLESAAGVSSIMKAALSLQHGVIPQHLHFKKFNPHI
AVDAAKFLIPTEKMEWKGGDKKRRVGISSFGFSGTNVHMVLEEAPVRREVINATERASHI
LTLSAKSEASLAAMARRYADFLKDDLLNGKPAAIADVAFTANTARAQFEYRAAVVANDAA
TAADKFRQLSEGLTPAGVFKSEGKPVNGVAWLFTGQGSQYAGMAKELYESSPDFKQKLDA
CEKLFEAETAESLLAILWGDQSSLIDNTRYTQPAIFALEYALASQWQNLGLKPAAMVGHS
VGEYAAAVVAGIMSLEDAMKLIVARGRLMVELCERGDMAAVLAPLAQVEEIITGIDGVQI
AACNAPGNHVVSGTAEGIKVVLQKAAAVDVDARLLVVSHAFHSGMMQPMLESFRKVAESI
TYKPAMYTLVSSVSGCVNQGEMSTAAYWVDHVRRTVLFVNALKELATLKINLCLEIGPGA
TLTSLAQQSLGQDGYIFVHSLRARQDASRQFNLAVAQLYARGVDIHWKNFDAPYARQRVA
VPCYAFDRKRYWLGDNDNGMISGSGNIGHDTGNVLMMLQSPMSDDVFFENAFGGRHPFNL
DDHRLYDVVVAPGAFHLANTLLCARDAFGDKPVKLDDVVFPEPLIIEGDKKRRLHYGFKK
ITTKDGAENYEVKGFSRPDEKGAERDWTLHCSMNVTPCSGPDTQQVLTAQDIEQIQARAS
HHFSGQMFYDEMWKVGYQLGSQFRWIAEFWRRPGEALTRLRLPESALEQGKYLIHPGLMD
SCFQSSALATMYEEFDSSTVDAIYIPFALENFHFFQKPTTTLWCHVKIKNPPEDPRAAPE
SFSHTIQVYDDQGNILIDVETLHSKRAPKEALLRALRKDAQDSHYEIHWKSGNIPADQEL
RALPDTLLVIGDNNSLAATLCAELQSRRVNAVQVVCKAGCSYTHKSSYTHENGKATLNPE
DGGQWMALIQSLGGIAKLGGLVYVAPEAELHREAEIMDLELQLFTPILNMLKALQLLSGS
TSPRLWCVTRNAVTAQRSDTGLNPVHTALTGFGKVLDMEHPEYAAVLIDVDGESDERTAR
AIITELQLPAKEKQVALRRGSRWVARLARTGIAAQGMPIPPAPYRLIIEKKGTFEDLKFV
PFKPRELGSTQVTVKVLSAGLNFRDVMGVLNVYPGEAGPLGGECIGEIIELGKEVTRYKM
GDVVMIPLTESCMSTQTFAEEALICRVPRNLSLNEASTLPVVYCTALHGLKNLAQLKKGE
RVLIHAGAGGVGMAAIHIAKHIGAEVFATASEKKRDYLRKLGVEHVFDSRSLDFAQDIRR
VTGGAGVDVVLNSLAGDFITTSMALLNPGGRFIEIGKADLWTQDRVKAFRDDIAYEAFDL
VIVTLQNPLALKSLMDEVVENVEAGHYQPLPYTVFKHKEAMEAFRYMAQGKHIGKILINP
DDAAITVKRDRSYLITGASGGLGMLFSKWMAEQGAGEIILAARRDVRELDAPGVAAIEAL
GAKVTTLKADTADRESVRAMIESVQKNCLPLAGILHAAGVLADAFVVNQDVASFRKVMGP
KLAGAWYLHEETQHLPLEMFVMFSSLSSMLGAPGQANYAASNAFLDGLAAYRRAKGLPAI
AVNWGPWAEVGMAANSQVEANAEASGVHLIPPADGLSWFAQVLQTNPVQRGLMLIDWAAL
ANLSGSIPAFLSELDVKASVGLDANLQKMADEFRTSLADAPIDERTSMLIDKICEQIKRV
MGLDESDSINPNQPLQELGLDSLMAVELRNILCALIGKQLPATLMFKYPTVASLSTFLIQ
DLFPDEIAAAETKTVEPKQEEKIQDEDKQLDDLTQDELAAMLAAELGDSRD
>S5XXF6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Paracoccus aminophilus JCM 7686|TrEMBL
MSLSDDTAAPAAPAEERGAAQLRRAMGALRKLQTELSQLKQAQNEPIAIVGFAARMPQVG
ASTDAFWEQLLAGADLTAPPSARRKAPCATGLPQKAGFLPEIDCFDASRFEISPKEAGRL
DPQHRILLELADAALDAAGLGSRAGHAAGPRKIGVYVGMSSGDYRELLDPQSAQLDAFCA
TGTTPCFSAGRISYALNLTGPAMVVDTACSSALVALHLACAALRRGECDAALGGGVNIIT
SAFAQALLEETRSLSPSGICRPFDARADGFVRGEGGALFVLKRLSDALASGDEIRAVIRG
SAINQDGKSNGLTAPNPEAQTAVIREALRNADLSAEAISYVEAHGTGTALGDPIEMEALT
EVFARAGEPCRVSSVKSNIGHLEAAAGAASVLKLALCMARHQLPAQSGFATLNPHIAQSE
GAPEILAEARDWGKAGETVYAGVSSFGMSGTNAHVILSSADDYAPARAPTTSELGEALIV
PLSAADPERLLRRAAELGARMQSAPDPVGAAAACCLAAGGQLERMAVVARDPRELSQRLL
DPPLSNPNVLRGRRDPNTRGKVAFLFSGQGSQYAHMGAALYRSSASYRQAFDACDALFSP
LLGESLRARVFSDDGGLERTEWTQPALFAVEYALAAFWRALGVEPDFVAGHSIGEYVAAT
VSGILSLEDAIAMVAARAQAMGALPKGGAMLAAWCDGQTTAQIATEICAESGGPLALAAT
NSDNQAVLSGAEQAIAEAERRLNARGVRTQRLVVSHAFHSPLVAPAVAGFRAGCETIEFA
PPKIPIVCNLTGKRAAAQELASLDYWSQQIVSTVRFAETVQTLRDNGVTTWLEVGPHPVL
TPMLGARSNENAAASLLRGRDDCLTMSKAVAGLWVAGVPIAWDKLFHGSAPHWRVSPEPV
ARLSHWLPSGLSRTETLSSADAAAGASVAPPQPNATEAALEAPVEASIEIGWHSFELPAQ
IAAMPAILLPLAPEAGEDFIQIAATHTESTVLDPGWTQGATVAEMRDALLGEWDRQIAKD
STAVANVFVLPPQRIDTSAELGRELAVCTAVFQALSKRRDRQPLRLWLVTRGGQLANGME
AQAVSAAAVHHGSLGGFAQVAALEYPDLVQGVLDLPLVEEASPADLARGLQAVEDNQHDW
LALREGRVYGRIATSAAPRPPAGPVEFAAQDWVIVTGGLGSIGLATLEWLAARGARQLLV
ISRSAVDCADPDRRDKRQRCLARLAAAGVRCEIFVGDAADPALLGSAVDFAADHGGLGGV
FCLSGTTSRQNLDDMSATIDPLPLVSKLESASILSALCPEVRHFVVFSSVSALWGTPGEA
VYAAANAGLDRLIAARRQCGQSGCALHWGAWAASAMVGDADQEWLARLGMTALSAQDGLA
FLSEELDAAPAAGPSTSGHRVLARMDWRRFVATYQARRRYSLFRDLGAMLDLSPAQGNQR
QGPQSARAIAELVERTVSTILGYDEGQSLPTNRGFTELGMESISAVDLARALSAQLSVAI
TPATVFDHPTVERLSEHLAKEMLKDEGPAQPMAAKAPHSPEPQTARQTIDQDVSQSTGRP
VAPTGEAFAIVGVGCRLPGGVRDLDGLWRLLSSGKDGLSDIPWARWPHAGADPALYVRRG
GFLDAVYSFDASFFGISPREADFMDPQQRLLLQCSWEAMQDGALFQSDGAPKDTGVFVGI
SNSDYGLMMARSQIDQYFASGSALSAVPGRIAHYYGFEGPTLAVDTACSSSLVALHLACQ
ALTRRECATALVAGVNLMLSHEVTLATCRNRMMSEKGRCATFDAAADGYIRSEGCVVLAV
KRLEDAQLNADRILGVVRGSAVNQDGASSALTVPNGDAQRRVIARALENAGLSGGQVHYV
EAHGTGTPLGDPIEAEAAWDAYRGNSRDPAPLWIGSVKSNLGHLEAAAGLAGVLKGLGIL
RHGQIPASLHFQDPNPHIPWDRIGLRVPQQIVPLPAQEAGLVAVSGFGFTGTNAHVLLGR
APEPDAATLAEPESRADHAALAQHGLLSARSPAALTALIETYLERFAQTDRRDARARLRE
ALNGRSQQHEFRAVLAFDEALRPKAQARAETAARFQTRLRLDLRGRPVLGAGAADLLRAL
PEIAALTGPMDGDPAEAALLATLAWMRLLGLEVEVVGAAWLGSASPRAAMVAPLNGPAPV
ATGTSQKADDRLNWVVTDDRIIAPDGTEIMPSARLADTWDALLAALFLNGMRLKMAALTG
GRMVRHAPLAAYPWQLKDYRLPRAAGQPVFTMEAAQGAQSLAIGAHRADHPAYLTDHRLF
KTVVVPAASHLAQLLVLLRREEAAATVIATDLAFPRALVLDDAEDVAVQIAIEGQPDAPR
TLKVRSAKEAGTDAWTPHLVGRIATAAEGGDALARWADVPAIPAQSHEISGKDFYAYFAA
VGYTLGPSFRWIDRIWRREHEAFCRMKQPVLPDRVEDYSLYPGLIDSCFQLLACWMVTEG
SAEDDALAIPFHCDRLTLSTKPPQGELTCHMRRRRSGDFDSQSEVVDIDLYDETGARYLE
ARGFRTRRAAREVLQRSLHRGGGISYVEDWQVAPLGESPVEDRGGRYLLLSDGGAQAQSL
TERLTAAGHEVAVLTLAPEDLADLSQIREKLRAALGGRGVDHVVSLWGRAASPAETTPHD
TGPHDTTPHDTRLTFATTLVTAVSTALQGVLAHGGDSPGSINLVTEDAVSVTGEGIVLPE
RATLVGLASALRRELPGTEVRLIDLEDAAADDWSATLVAELARADEPRLCYRAGQRWVAR
LRPADPSAAEAPHLPEDRSFVITGGTGLLGLKIAERWIGHGAKRVALISRGQPSEAVRAR
MADLAADLAAEVAFYQADVGDLDQLRAVLHRIRADLGPIGGVIHAAGVLTDAAFAQQSPE
LFATAMSAKAGGLRWLDQETRGDCLSHFIVFSSVASRLGSAGQASYAAANAFADALIEER
RLQGLPGLAVNWGPWSGGGMLAEAGAAAQRRLDLLGVHELDETGLAALDEALTSPGSHRI
VIDADWDRYKAALRRPDPLFDALGTARPVAPEPAEAAPRAGLLRRLSEARTAQRPEILSQ
GLTEIVARIMNIDDLGSVNWSLGFTDLGLDSLMALDLQSRLKDELALEVSATVALDYPDI
ERLSAHLLDQFDFGPTEELSSEDALLEAALKQLNQLNGTGV
>A0A1Y5PHC1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|uncultured Mycobacterium sp|TrEMBL
MAALQAKFPGAPEIPASELANLRTLQDVVDTVSGFAAGGRTEQGAAVQQSAPESVAPVGL
SCTEAELRAAPPSGLAMAGLRDGVVFITREDPAFADALERALNARGLQAKTVEEAPAEAG
AVISLAALAPACTPDDCVAVHVRAFHAARSVAKSSARTRLFVTVQSTGARFVAADVPLGV
ASLVKTAGWEWPNASVRAVDMETLDAERLAAELLEGGSGIEVALRADGTRLVAVDDIESS
VGEGETISVAPGGVVVVTGGARGVTAESALALAKQHGLRLALLGRTPLREVTADEPSGAT
SAEIATALAASARARGEQLSLPQARAQAESLLATREVRTTLASAENQGTPARYFAASITD
EAALRSVLNEVRQNFGPIVGVVHGAGVLADKRLEDLDDDGFVKVFTTKLIGAEALLDATS
TDELRFISLFSSIAARAGNPGQAAYASANAALEAIAARESARRNGECVVRAFGWGPWDGG
MVDATLKSRFLAGGVGVIPIAEGAQFFAEHALCRSSASAVVVAAPAEPRLRAARLDWEVS
AENLPVLTDHQVRGRVVVPVVIALDAILRAARGLLADACPVVRDFQVLSGVTFAEHERQS
LTIDFEPAGSSYTVSISDADGRARYRATVDTAAVASPELSVPQVSGSAWPLGVDEAYAGP
LFHGPQFSVIEQLDAFGTAGGTATLKSLGDLDWPQSGWAIDAASIDGGLQLGIVWASAQG
RPLVLPVRIGRVVLHRAFGDGSIGRCRLAAHPVNDKRVDFDIAYETSDGALVATLEGVEF
YAAGTAADTSA
>X8EZR1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium ulcerans str. Harvey|TrEMBL
MSQARHTGKIVLTAPVVVDPEGTVLITGGPGRWVPCSPSIWFLPMVSGICC
>A0A6B9BA51|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium avium subsp. avium|TrEMBL
MSNDAYDAESVDPVVIVGMGVEAPGGIENAEGYWDLLVHGREALGPFPTDRGWAVRELLA
GSRRSGFKEIHDHGGFLCGATTFDPEFFGISPREAVVMDPQQRVSLRVAWRALENSGINP
DDLAGHDVGCFVGASATGYGPEMARFSEHSGHLLAGTALSVISGRIAYTLGLAGPALTLD
SSCASALVAFHVAVRSLQNDDCDMAIAGGVNVLGSPGFFVEFSKQHALSDDGYCRPYSAQ
ASGTVWAEGAAMFVLQRKSTAVRAGRRILAEVRATAINQDGRSAGLSAPSGDAQVRLFQR
AITQAGIKPAEVGMIEGHGTGTRLGDRTELRSLAQTYGDTEAGAGALLGSVKSNVGHSLA
AAGALGLAKVLVSAEHGAVPPTLHAGNASPEIDWDKQGLRLAQTLTPWPATDGQRIAAAS
AFGIAGTNAHLIVSVPEVA
>A0A3N6H1R9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-17|TrEMBL
MAPHEAEFWQAVESEDLDALMGTLDKAEAEPLRAVLPALASWRRNSRDSSTIDGWRYRVD
WKPLPKAKSAELSGTWIVLVPEVLRDDASVSACGRALAGHGADVVTLAVSSADAGRKAFA
GLLGELLEGNRTENGTENGTGNRTENPTVDPSRIGGVLSFLGADEAPDPAHPAVPAGVTS
TLALVQALDDVELQAPLWCATMGAVQVGTADRTVSVAQAQVWGVGRVACLERPGNWGGLV
DLPAGGVDARIADSLCGILAGRTAEASGPGTGDTGGTGEDQIAVRSAGAFGRRLVRAPLN
GAPAVRPWSPEGTVLITGGTGALGGHVARWLAGRGAERLVLTSRRGAEAPGAAELEAELT
GLGAKVTVEACDVADRDQVAALIERLNTEGDPVRAVVHTAGVSDSAALADTEPAAFADVL
AGKTAGAAHLDELLGGTVDAFVVFSSIAGVWGSARQAGYAAANAALDALALRRRARGWAA
TSVAWGQWADGGMAAGDTGEQLTRLGLAPMAPRLAITALQQAIEHDEAPVVAVDVDWPRF
ATAFTTLRPSPLIGDLPEVRAALAPEEDEADGASAFTGADRAETLRQNLLELSGLEQEHL
LLELVQERAATVLRLAAPTDVRSDRAFRTLGFDSLTAVELRNQLGEATGLRLPAALVFDH
PTPTALVTYLRSKLLPEGVGTGTDGGPGGHDDLDEAAVRGALATVPLDQLRAAGVLDTLL
KLADRRGGAQTPPPAGDETESIDEMDAESLIQMALGDGES
>F1TAA5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
MSEMNEIVVRLLWGQLQSIGLFTQKSSVFADFKTKSGLWKLYDKWLSESIAVLVRNNYLQ
YDGELYTVVDGTKLDMETVWNEWELKKGLWLKNPDIKDYVILLEAMLRALPGILTGKIPA
TDIMFPNSSMQLVEGIYKNNPVADYFNGVLADTLVDYIKERIEQQPSAEIRILEIGAGTG
GTSAMVFQKIHPYQKHIREYCYSDISKAFLIHAEEVYAPGNSYLTFKIFNVEEPIAGQDI
TAGGYDVVIAANVLHATKNIRQTIRNAKAVLKKNGLIMLNEISVNSLLTHLTFGLLEGWW
LYEDAELRIPGGPGLYPENWQRVLQSEGFRTVFFPSREAHDLGQQIVVAESDGVVWQKRQ
RARVEEPEIPKLKSGMGKSSPANHRKLQSTAIQDKPPKLQKTKTIRDADAGDQMLKDHAR
AVVRESIASSLKMKEEIIQDERSFSEYGVDSIVAVKLVNLINKQLNIKLQATDLFDFSNI
KKLVQFIARDFRAALISQLSENTSVLEIDHIGNQGEVISAAQEANDIHSNKQVWQKNRLA
AQYAKTAQYSVNVTEQDQAAGYREDSIAIIGMSGRFAKSDSVDELWNHLSNGTDLVEEIS
RWDLSKHFSKGVRYCNYGSFLSNIDQFDPVFFNISGLEASYMDPQQRFFLEESWKALEDA
GYVGTGIQGRSCGVFVGCAPGDYKLLFDDNLPAQSFWGNAGSLIPARIAYYLDLQGPAVA
VDTACSSSLVAIHLACQSLWNRETDMALAGGIFIQSTSEFHLACNRATMLSLTGHCHTFD
EEGDGFVPGEGSGVIVLKRLKEAINDGDHIYGVIRGSGINQDGTTNGITAPSAKAQERLE
RYVYDTFGIQPAEIQMIEAHGTGTRLGDPIEYQALTRTFRQYTDKIGYCAIGSIKTNLGH
AVTAAGIASVIKVLLSLKYKKIPPSLHFKKGNSNIQFENSPFYVNTSLKDWNVNSGSKRR
ATVSSFGFSGTNAHIVIEEAPEIDLVHSQKPSYLIVLSARTFEQLRQQVSQLVEYCEREP
KVDCGDMSYTLLLGRKHFNHRLACVVHSLEELIKLFKKWLAKGKLLEIHISEIQENGNGE
QPSLKRYGNQCIQNCHEVNDGGNYLEYLSMVAYLYTQGYALEFEQLFANDRYSRISLPTY
PFARERYWVPEIESSPTMAAPAAAFIHPMLHQNTSDLSEQRFTSTFTGQEFFLADHAVQG
QHLLPGVAYLEMARAAVEQAAGALKEEKTRISLKNIAWVRPVEVGKQPVRLHIGLYPEET
GWIAYEIYSEPDEADTEPIVHSQGVAVLDTDRKAPVLNISALQAQCSQSSLSSHQYYEAF
KAMGFDYGPAHRGFEQVYVGQNQVLARLILPPSVAATKDQFVLHPSLMDSALQASMCLMM
NDGEIMPYNSNTPGRPALPFALEELEVFESCLPTMWALVR
>A0A4V0ZJW2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomonospora litoralis|TrEMBL
MTANETRLRDYLKQTTAELRATRSRLREHEERGREPIAIVGMACRFPGGVRSPEDLWDVV
EPGRDVVAPFPADRGWDTAGIYDPQGERSGTTYAREGGFLEDVALFDAGFFDISPREATS
MDPQQRIFLETSWEAFERSGIVPASLRGSSTGVYLGATDHDYGRGISPVPDHLRGNLLIG
RSGAISAGRVSYVFGLEGPALTVDTMCSSSLVAMHLATEGLRRDECTLALAGGTTVMSTP
EGFIEFSAQQALAPDGRCKSFGAAADGTGWCEGVGVALLERLSDARRNGHPVLAVVRGGA
VNQDGASNGLTAPNGRSQRRVIKQALRSARVTAEEVDLVEAHGTGTSLGDPVEAHALLAT
YGQGRDGLPPLRLGSLKSNFGHAAAAAGIGGVIKTVMALRNGVMPRTLHAEEPSPAIDWS
SGRVELLAENRPWERNGHPRRAGVSAFGASGTNAHLILEEAPEEAAPAEEPEDSAAADDG
AGTGGTGAPAARQDTRTAGGAESPAGVLGPGAPIPWLLSARSETALADQARRLADHLARR
PGTGPADVAWSLATARTAFEHRAVVTGTGAGELTAGLDALAAGAEHPRLTRGRVVADRGR
TVFVFPGQGAQWPGMARGLAEGSPVFAAALRECADALDPLVDWPAHEVLRNGGDSASAVD
TDRVDVVQPALFAAMVALARTWRACGVEPAAVVGHSQGEIAAACVAGALSLEDAARVVAL
RSRRLREIAGGGGMLSVGLSRDRALDAVAQWPDLSLAAVNGARSAVVSGAGESLDGLAAQ
LERADVRTRRIPVDYASHSHHVERLHAGISADLAGVSPRSAEVPLYSTVTGEAIDTSEMG
ADYWYRNLRATVELDAAVHALSRTGHTTFAEVSPHPVVLPAIEETLDRLDTARAVTGGTL
RRDEGDLHRFLASASHLHTRGVGVDWPAVLADLGGAPTDLPTYAFQGRRYWMEAAQPDDA
GSPDGAAGAEADAEFWEMVSTADPQTLAENLGIDPAQPFSAAVPALARWRERHRRRRDTD
TWRYHESWVPLQEAAGPRLSGRWLLLDHERGGWDDLRRGIADQLGRHGARVERIVLAEAE
EGRAALGARLRDAAAGGVAGVVSLLALDRGEQPGHPGLPRALASTFTCVQAFADSGIDAR
LWAATCGAAAVGDTEHVAAPDQTAVWGLGRVAALELPDRWGGLVDLPADAALSDSAARRF
AGALLAGTEDQIAVRSPAAYGRRLRRVDAAAQRAPRWRPRDTVLLTGGTGGVGAQVARWL
AELGAPRLVLTSRRGGAAPGAEALAAELRELGTDVEIAACDAADRDAFAAIRERAAERGR
PVRAVLHMAGAGVLRALDATDTGEYADTTYAKIAGADVLDELFSEPGELDEFVLFSSISA
AWGSGEHGAYASANAYLDGLADSRRGRGLPGRSVVWGIWAPRDGGGMAAGLAEEQLRSRG
IPFMDPAAALEGFHRVLDDDRAVEVLAEVDWESFAPVFTMARPSPLLETIPEAESALRRD
REEAGEAGESSLAERLAGMRPVDRARALSELVRSRIAAVLDYAGPDEVDPDRALRELGFD
SLTAVDLRNRLTTATGLRLPVTVVFDHPNAAALATHIGGLLLPAGDSGGGEGGDADRAPV
PDAGPDEIGDMDVDSLVQLALRSETQRGEG
>A0A1T9F0N6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus subsp. massiliense|TrEMBL
MTAVHVDPVVISGMAIEAPGGIDTPAAFWNALADGRELISAFPRDRGWPVDELLSLSNLD
GWGRISDAGGFITDASAFDPTFYGITQREAVAMDPQQRVAMRVAWKALENTGLNPGAVDG
SEAGCFIGISPNEYGPPVGEVNAHSGMRVVGRGQLGAAGRISHGLGLIGPSVCVDSACAS
SLAALHIAASAVRADECEWAIAGGVCVMGSPGGFYEFSRMHALDPDGHCRSYSDEANGTL
WGEAVGMVVLERESRARALGHRVYGRIMAVRTNHNGGGKPILVPRGRAQAKLVAATIAAS
GVDPADVGMLEGHGTGTRAGDPLEILALQSTYGAGGSNALLGSAKSNAGHAQSAAGMVGL
IKLLLSGQYGHIPPTLFADNPTTKIDWSMTGIRLATKLHPWEPKDGIRYGAVSSFGAGGA
NAHAIIAMPAMDTQGEDGDDF
>A0A2S9YGC9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Enhygromyxa salina|TrEMBL
MNEADPILQTDPEPSRRDLLARSLAELRATRSKLAELEARAREPIAIVGLGCRLPGGVDS
AEALWALLSAEADATSEPPPGRWDPRDDEPAWMYTRRGGYLDAVDGFDARFFAISEREAI
SLDPQQRLLLEVSWQALEHGAIAPQRLRGTKTGVFFGISVSDYAQLLTAQTPTAEVDGFF
GSGVGLNFGAGRVAHFLGVHGPAMVIDTACSSSLVAVHQACASLRAGECDMALAGGVNLI
LSPLGHAILCRAQVLSPEGRCKTFSADADGYARGEGCGVVVLRRLSDALRDGDRVLAQIR
GSAVNQDGPSSGLMVPNPSAQRGVIEAALAAAGVEPRAVSYVEAHGTGTALGDPIEVRAI
AEALGGQRERPLLLGALKANIGHLEAAAGIAGLIKLVVCLDRGQLPRQLHAERLNPALDW
SQLPLAVVDRLQAWPEGARIAGLSSFGASGTNAHMIVEAAPELPAAAPSGPPRPELLVLG
GADLDALRELADLVATQLDAPTARLADLCRGAALGRARLPETLALVARERAELGQRLRRF
ARAEDQPNAGFIQGRRPRRAPRVAFAFSGQAELQLGMGSELLASEPRFRAACERCDAHLR
PLLGRSLLALLRGDEPGDAAELDNTRLAQPLLVAFEWALAELWRSWGVEPELVIGHSLGE
YVAACVAGVMSIEDTLTLVARRAQLTAEHAEPGVMVAVFCGETQARRALGGVADAERELA
IAAVNGPTEVVLSGREAAVMAVVDRLAEAGVKARRLPTSYAFHSPLVDEVGVSLEAAVSE
LGVARARPSLPLISTRSGALVDDVLDPAHFRRHLRDTVRFADGLRTLVDRGVDHVVEIGP
GLTLSAIGRRRADEVRWLPSLRPDQDQRAAMLESLAVLVVGGLEPGWDAVLSPGRRVALP
PTPFRRRRHWLPARAGLARGPQPGRAAALEREDPDHPLLGRRCADAPERGAAFEAWLRAD
GPAVLRDHRVYDRVVVSGAVHAAMIEQALALVHGAEARFEICEVEFRAPLLLPEDGEVRV
RLELLDPDPNTARSEVTLFALDDRGGVVTITHAWAEPRAAEPAPPAQTLATLGQRWTETL
AGDAFYTRFFRSGEHELGPSFRTITAIHRRDGEALAQLRPPAVDRAEGLDQSLAQAIALS
EVYGQILMPAIPDYAATLSSLEHTFLGQGIDRVIDHVGAPARARWAYARLREFDGDQLCG
DVSLFDDDGELLSVVEGLRARRVPASFLRLRLAAAAAAVPSFDLDALERARPEQRRGLLA
AYVVGRIVAVVGGEPSFAGDEPLASLGFDSLMIVELHRDLRLGLAVDPPPAATLLGASVD
ELVDQLGVALLRVHGPGSGRVHGPAGAASGRSAGERPDGRGDGAPELRLRRLGEVASQRD
APRVLCLGDPAVFEPWTAALDGELELVVAAARPLRLGRLLPPRLRDAVSAAELIDALIEL
GAGPRRLALLGVGPGAGLALELCRELRHRGAPLPERLFVWGAPAPAAGTRRLAHAGALSA
MLAHGGQRARELLELAPLARASGASFEPSSDLGAAAKLLRPLAGELGSRWSRRHRHEAPL
STSIVALGSPALAPWSAHTSGRFVLHSVSGRPDRPDSVDPLELLTLIRRELS
>A0A5P9PJS5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Amycolatopsis sp. YIM 10|TrEMBL
MRALLADPGAPGGLRLGEAPEPVPAANQALVRVAATSLNSGEVVALLPDAPPGAVLGWDA
AGVVERAAADGTGPAAGTPVVTLGMAGAWAELRAVDTNLLGVVPEGADLGAISTVPVAGA
SALRALHRAGPILGRRVLVTGATGGVGRYAVQLARRGGAHVLASTGNPDRHGESLCALGA
HEVVDGPSSVDEPVHAVIDVVGGEQLVRAYAKLAEHGTLVSVGRSSGADAVLPPSALEGM
GGHDRSITTFFLLNHSGLAADLTWLAELVAAGELDPHISWRGRWDDAATAVAALRERRLS
GKAVLEIGH
>A0A3G4VQK7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-16|TrEMBL
MVNEDKLRDYLKRATADLRQARRRLREVEEQNQEPIAIVAMSCRYPGGVRTPEDLWRLVA
DGTDAIAGFPVDRGWDVESLYDADPDSAGSSYVSEGGFLYDAARFDPAPFGISPREALAM
DPHQRLLLETSWEAFERAGIDPTSLRGSRTAVFAGVMYHDYTARLDSVPEGVEGFLGTGS
SGSIASGRVAYTFGLEGPAVTVDTACSSSLVTLHLAVQALRAGECTMALAGGVTVMATPA
TFTEFSRQRGLAADGRCKPFAAAADGTGWGEGVGMLLVERLSDAQRNGHPVLAVIRGSAI
NQDGASNGLTAPNGPSQQRVIHQALTNARLTTAEVDVVEAHGTGTTLGDPIEAQALLATY
GQDRSADRPLLLGSIKSNIGHTQAAAGVASIIKMVEAMRHGVVPKTLHLDEPTPHVDWEA
GAVSLIGETVPWPQTGAPRRAGVSSFGFSGTNAHVIVEQAPEAEAAEPEAGSGMPVVPWV
LSGKSAGALRGQAERLSGWLAGTPDVDPLDVGWSLASTRAGLDHRAVVFGDHAAGVAAVA
SGALTAGVVTGSAVGGKTAFVFPGQGSQWVGMAAELLESSPVFAARVDECAKALEPFTDW
SLADVLRGVDGAPSLDRVDVVQPALFAVMVSLAEVWRAAGVRPGAVIGHSQGEIAAACVA
GILSLDDAARVVALRSQAIGRVLAGLGGMVSVPLPAAEIRERISAWGEERISVAAVNGPS
SVVVSGEVQALEELLASCEADGVRAKRIAVDYASHSAQVELLREELDTLLAPIVPQPAEV
PFLSTVTGEWVNGTELDAGYWFRNLRRTVELEQATRTLLEQGFGVFIESSPHPVLTVGMQ
ETVEDAGREAAILGSLRRNEGGLERFWLSLGEAYVRGVAVDWDAVFAGTGAQRVDLPTYA
FQQEHFWLESGTAEDPGTAAYPADATDARFWEAVERQDVAALIAELDIDGDEALTALLPA
LSSWRRQGKERSTVDGWRYRITWKPAPEPAATRLNGAWLVAVPESGGAADAVAGALAEHG
ADVRQITVPRTHDARARLVERIREALADGPEVAGVLSLLTPVAVEAEPIGSAAPAGVSAT
LALVQALGDADVAAPLWCVTRGAVSVGRSEQRADPAQAPVWGLGRVTALEHGERWGGLVD
LPAQADARTLRRLVGVLAGDAAEDQVAVRSSGLFVRRLVRARLAESPTVREWRPRGTTLV
TGGTGALGAHVARWLAGNGAEHLILTSRRGAEAPGAAGLREELTALGARVTLAACDVSDR
EALAALLASVPADQPLTAVVHTAAVLDDGVIEALTPEQVERVLRVKVDATLHLHELTRDL
DLSAFVLFSSFAATFGAPGQGNYAPGNAFLDAFAEYRRAAGLPATSLAWGPWGDGGMAEG
AVGDRMRRHGVIEMAPERAVSALQHALDRDETTLTVADMEWKRFVLAFTSGRARPLLHDL
PEARQAMEATRTDAAEDSGSAAVLAQRLAGQPEAEQERLLLELVRTAVAAVLGYAGPDAV
DAGRAFKELGFDSLTSVELRNRLGAAAGLKLPPTLVFDYPTPTVLARHLRAEFSGQSAAA
PVPTAAAGSDVEPIAVVAMSCRFPGGVRSPEELWQLLVSGGDALSQFPADRGWDVEALYD
PDPDAQGTSYTREGGFLSDAAAFDPAFFGISPREALAMDPQQRLLLETTWEAFERAGIDP
ETLRGSQSGVFVGTNGSDYSHLVRGAADGLEGHLATGSAGSVVSGRLSYTFGLEGPAVTV
DTACSASLVALHLAVQALRSGECTMALAGGVTVMSTPGTFIEFSRQRGLSTDGRCKAFSA
DADGFSPAEGVGMLLVERLSDARRNGHPVLAVVRGTAINQDGASNGLTAPNGPSQQRVIR
QALANARLTTAEVDVVEAHGTGTSLGDPIEAQALLATYGQDRPEGRPLLLGSVKSNIGHA
QAAAGVAGVMKMVLAMQHGVLPQSLHIDEPTPHVDWSAGEVALLTERRAWPETGDRPWRA
GVSSFGFSGTNAHAIIEQAPVEQGSDEQGTPAPPTPHPLLTTTTPHDTGSDPRTPLPWAL
TAKTEKALRGQADRLLDHLATRPDLRRVDIGHSLASTRTAHDRRAVLIGRDQREHLAGLA
ALAAGGTAPLLVQGSVIGGKTAFVFPGQGSQWVGMAQALMDASPVFAARVDECAKALEPF
TDWSLVDVLRGVDGAPSLDRVDVVQPALFAVMVSLAEVWRAAGVRPGAVIGHSQGEIAAA
CVARILSLDDAARVVALRSQAIGRVLAGLGGMVSVPLPAAEVRERISAWGEQRISVAAVN
GPSSVVVSGEVQALDELLAACEKDGVRAKRIAVDYASHSAQVELLREELDTLLAPIVPQA
AEVPFLSTVTGEWVKGPELDAGYWFRNLRQTVELEQATRTLLEQGFGVFIESSPHPVLTV
GMQETVEDAGREAAVLGSLRRNEGGLERFWLSLGEAYVRGVAVDWDAVFAGTGAQRVDLP
TYAFQSQRFWPEAAPVEAGELPVESAIDARFWDAVEREDLAALTAELRIEGDQPLTALLP
ALSSWRRQSREQSTVDGWRYRVVWKPLAEAATTRLSGTWLAVVPEAVSGPAGDAAAAVLR
TLADRGAEVRTVTVAADAAGREALTAALKTATAATAPAGVLSLLALGDDRAALRAHSGLL
GTAALVQALGDADVSAPLWCVTRGAVSVARSERLQDPAQALLWGFGRTVALEFPDRWGGL
LDLPAQADDRTLERLAGILAGDGSEDQVALRASGLFGRRLAHAPLADAPTPPGWRPRGTT
LVTGGTGALGAHVARWLAGNGAEHLILTSRRGAEAPGAAGLREELSALGARVTLAACDMA
DRDAVAALLATVPADQPLTAVVHTAGVLDDGVIDGLTPERFATVLAPKADAALTLHELTR
DLDLSAFVLFSGVAGTLGDAGQGNYAAANSYLDALAEQRHADGLPATSVAWGRWGDSGLA
AGGAIGERLDRGGVPAMAPRAAIRALQQALDHAEPAVAVADIQWERFTPGYTAVRPSPFL
VDLPEVRALVRAAAAAGDAGGAAGEGSPAEALRRRLSVMPQAEQALAVLELVRSHAATAL
GHPTTDEVGAGRAFKELGFDSLIALELRNRLNAATGLKLPATLVFDHPTPAVLADFLRGE
IVQDGSAAAAPGIAELEKLESALSVIDPDGETRSDIASRLQALLAKWGEPQAHSSGGAVA
EKLQEATADELFDFIENELGI
>A0A221W447|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinoalloteichus hoggarensis|TrEMBL
MNEDKLREYLKRVTVDLHETRERLRDREAADREPIAVVSMSCRYPGGVRSPEELWELLAA
GEDAVTGFPADRGWDLDALYDPDPDAPGTSYTRRGAFLHDAGWFDASLFGISPREALGMD
PQQRLLLEATWELFERAGIAPTSVKGSAGGVFIGAGLSGYATGLRSVPEDVEGHLLTGIS
ASVASGRLSYVYGLEGPAVTIDTACSASLVALHLAAHALRRRECDFAIAGGVAVLANAAS
FVQFSRQRGLAVDGRCKAFSDDADGTSWGEGVGLLMLERLSDAQARGHEVLAVLRGSAVN
QDGASNGLTAPNGPSQERVLRQALIDARLAADDVDAVEAHGTGTTLGDPIEAQALLSVYG
RDRSPEQPLWLGTLKSNIGHTQAAAGVTGVIKAVLALRHATLPKTLHVSEPTSHVDWSAG
NVELLREAREWPATGRPRRIGVSAFGVSGTNAHAILEQAPTAGEQAAGGKRPGTELGHRS
PTAAPRDTVIVPVRVTARTEPGLRAQAARVLAHVEQHPDLALADLGYSLGTSRADLEHRA
VVVAADRAAALDGLRAAAAGERHPAVHTGVAARGGGLAVLFSGQGAQRVGMGRELYAAFP
VFAESFDAVCAEFDGLLPHGLAEVVFDDPGTELDQTVFAQAGLFAFEVALYRLLESWGLL
PDLLTGHSLGEITAAHLAGVFSLPDACRLVAARGRLMQGLPEGGAMVAIAAAEEEVRPLL
AETAAVAAVNGPKSVVVSGAGDAVTALADHFAGLGRRTRRLTVSHAFHSPLMEPMLADFA
EVAAGIRYEVARLPVVSLVSGDVAGAEISTADYWVRHVRESVRFADGVATLRAAGITRFL
EAGPRGVLTSLVADLVADVAAVTAVAALRTDRPEAEALTAAVSALHAAGQPLDWAALLPG
ARRVDLPTYAFQRDRYWLSDAAGDASAAQAGADPFWELVADRELARALGVADDAPLDEVL
PALTRWHRERAALSTVDSWCYRVTWAAQGDSDLRPAGRWLLIVPTGRADTPWAAGLAAAL
AAGGAEPIVLDHPGLAATRQAVATAIQAHTGPDLAGVVSLLGLDDSPHPDHAGLPGGLVA
TATLVQALGDAGLTVPLWLLTDGAVAAAGDDPVHRPPQAALWGLGRVVAQEHPERWGGLI
DLPESVDDRGIRRVLAALAGGTEDQLAVRAGGLLARRLTRAPGVATERAGWRGGGTVLIV
GGTGALGGHAARWFAHNGADRVLLAGRRGPDTPGVAELVAELTDLGIHAEAVACDAASTD
DLRAVLAAIPAATPLSAVVHAAGVLDDGVVDTLTPDRLAAVLRAKVQAATNLHELTAGTD
LSAFVLFTSMAGVVGTAGQAGYAAANAALDALAQRRTRQGLPATAIAWGPWAGGGMAADE
LVAERARRGGVRTMSPELAVTALGRAVWHPGADLLVADIDWSRYAPLLSRTRPSPLLRDL
PEAVHAVPASATVGDLGLRDALAGRSPAEQQAVLLDLVRVQAAGVLGYAGPAAIDADRAF
RDLGFDSLTGVELRNLLGAASGLTLPSTLVFDHPTPAALAARLAEEFGVPTGGAVSPAEV
RADSGEPVAIVSMSCRLPGGVRSPEELWELLAAGTDAIGAFPRDRGWDVDALYHPDPDHL
GTSYVAEGGFLDDAAGFDADLFGISPREALAMDPQQRLLLETSWELFERAGVDPGATRGS
RAGVFVGTNGQDYQLALMGAVDAGEGHSGTGNAASVVSGRVAYAFGLEGPAVTVDTACSS
SLVAMHLAAQSLRSGECDLALAGGATVMATPGAFVAFSRQRGLAPDGRCKPFAEAADGTG
WSEGVGLVLLERLSDARRNGHPVLAVVRGSAVNSDGASNGLTAPNGPAQQRVIRQALANA
RIAADGVDVVEAHGTGTTLGDPIEAQALLATYGRDRVEGRPLWLGSVKSNLGHTQAAAGV
AGVIKMVEAMRHGVLPKTLHVDAPTSHVDWTSGAVRLLTERREWPEADRPRRAGVSSFGV
SGTNAHLVLEQAPAESDAGASDVGGSGAAGAGAERPDTEGTGTEESRDRPARPSLPLVPW
PVSARSGVALRAQAARLRDFVTDTPALDPVDVGSSLATTRSTQPTRAVVLGVDRTELLAG
LDALAAGQAGPLVVTGAASPGGLAVLFSGQGAQRSGMGRGLYGAFPVFAEAFDEVCAGFE
GLLPGSLAGVVFGDADADADADAGAGAGAGAGAGVGPGLDIDRTVFAQAGLFAFEVALFR
LVESWGVRPDVVTGHSLGEITAAYVAGVFSLGDACRLVAARGSLMEALPEGGAMVAVAAS
EDEVRPLLSDAVSLAAVNGPRAVVLSGVESAIGSLEQHFVVLGRKTRRLSVSHAFHSSLM
DPMLGEFAEVVGGVRFESPRLPVVSLVSGEVAGAEITTPEYWVRHVRETVRFADGVTTLR
GLGVQAFLELGPQAVLTPLIEGGEGDQDVTAVAAARRDRPEPETLLAALAALYATGVDLD
WAALLPDARRVDLPTYAFQHERYWPEPAAGAVDEGEQGTDAAFWAAVAENDLDVLADTLQ
VDRAPLRDVLPAMNAWRRRLAARTEVESWRYRVHWEPLLDLAAETPAGEWLLVTGEDDAD
PLADSLRVEGVRITPLRRVDDLVGTLAASAVAPAGVLLADPDVADVLAALRALADARADT
RLWVLTHAAVATGRADPLADVEQAGLWGLGRVAALEHPSRWGGLVDLPTTTDRRAVTRLC
RVLADGGEDQVAVRGSVVLGRRLVPAPLTGRAPAGPAPAGPVWRGTVLITGGTGGLGAHT
ARLLARSGAEQLVLLGRRGPAAPGAADLLTELTALGVRAEAVACDVTDRAALAALAARLD
AEGTPVRAVVHAAGITGHRPLAETTAAEVAEANHAKVVGARHLHDVFADVELDAFLLFSS
IAATWGSGGQGAYAAGNAYLDALAEHRRARGLAATSVAWGPWAGAGMAAADGAEEALRRR
GLRPLEPGAALAALHASIEHGLTTTVVADVDWSVFAPGFTALRPSPLLTAVPAAEAAVAA
AGVGGAPSGGAGDALRARLRGLAAADRDRAIDELVREQIALVLGHGDAAAIAPDRAFSDL
GFDSLTAVELRNRLAGATGLSLPATLAFDHPNSAALARLVRTELLGAEDGPAPGTRAAEA
VDLADDPVVIVAMSCRLPGGVRSPDDLWQLVADGTDAISRFPENRGWDPARLGGEQIARQ
GGFVYDADTFDPDFFGISPREALAMDPQQRLLLETTWELFERAGIDPTALRGSDTGVFIG
AGSSGYGAALTEVPDGVAGHLLTGSASSIASGRIAYALGLEGPAVSLDTACSSSLVALHL
AIQSLRRGECGLAVAGGVTVMSTPNAFLEFGRQGGLAPDGRCKAFADEADGTGWAEGVGL
LLVERLSEARRRGHDVLATVRGSAINSDGASNGLTAPNGPAQQRVVRQALTGAGLTPAEV
DVVEAHGTGTALGDPIEAQALLAGYGRDRDPDRPLWLGSIKSNIGHTQSAAGVAGVIKMV
QAMRHGVLPRTLHADNPTTKVDWSAGTVRLLTEPVPWPETDHPRRAAVSSFGISGTNAHT
ILEQAPPPEPAARPAPDDRAVRPAPWLVSARGAEALRAQAARLHASLGEADPLDAARSLA
SGRATLEHRAAVLGRDRAELLDGLRALAEGEPAARVLTGVARPGGRSAFLFTGQGAQRAG
MGRGLYAASEVFAEAFDAAAAYLDAELDRPLATLVFAEPDSPQAALLDQTGYGQPALFAY
ETALFRLAEAHGLGADLLVGHSIGELVAAHVAGVLSLPDACRVVAARGRLMQALPEGGAM
VALQAGVDEVTPLLSTAVALAAVNGPASVVISGDEDAVSAIAAEFESRGRKARRLRVSHA
FHSPRMEPMLAEFGRVLSTVDFRAPRTTVVSTVTGRPAAGGELCGPDYWVEQVRATVRFG
DAVAHLDAAGVTRLLELGPDAVLTAMTAAALPPNDARACVPAARADDADEQAAFTAALAA
WHVHGGGVDWTPLTRGGRRIDLPTYPFQRRRLWLDTPAPAPSTEDGPLWDAVERSDLAEV
TRALGVAEDASLAEVLPALHSWRHRLHEAAVTDSWRYDVVWRHLDSPGEHHTPGSWLVIE
PEDDVEYLAALTDELVRQRHDVVRLAWSAAVGDPARLVAAAADVTGVLLPATGGDTAAAL
PALLRALTEAGVTVPLWCLTRGAVGTGPGDPVLDPAQAMIWGLGRVAALESPRGWGGLVD
LPAAPDTAVLRRLPGVLAGVAGEDQLAVRPAGVFVRRLVRATVSAADPVWSTSGTALVTG
GTGALGGQVARWLARSGAEHLVLTSRRGLAAPGAAELAEELRGHGVAVTVAACDVADPEA
AAALLRDLAGRGERIRTVVHAAGVSEVSPLVETSPEQFERVVAGKVAGARNLDAAFADAD
LDAFVLFSSIAGVWGSGGQGAYAAGNAYLDALADRRRARGLRATAVAWGPWGGGGMAAGS
EAERSLQRHGLRLLAPELAVLTLRRVLAADGAGAVVADVDWSRFAPGFTGLRPSPLLGEL
AEVAAAVREATPDGVSSGAALRAALASAEPDERHELLVRLVREQAAVALGHRDAAALDAE
RAFADLGFDSLTAVEFRNALTSATGLRLSATLVYDHPTPAVLAGALLAELVPAAEPVDPA
EAELRRALAATPLERFRKAGLLETLLRLAEDGAAGAEGDESPEEYDALDAAALIERALGT
SATARVEG
>A0A4R8SDY3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides salmoniphilum|TrEMBL
MSQMSPTAAMESDPIVISGMSIEAPGGIETPGAFWAALADGRELIGPFPRDRGWPVDDLL
SVSKLEGWGNVCDAGGFITNAASFDPAFYGITQREALASDPQQRVGVRVAWKALENAGIN
PGSLDGAEVGCFFGTSPGEYGPRAGEANEHTGYRIVGGGQLGVAARVSHGLGLTGPSMCV
DSACASSLSALQLAASSVRAGECEWALAGAVCVMGSPGAFYEFAKLHALASDGHCRSYAD
DASGTLWGEGAGVVVVERESRARSLGHRIYGRIMAIRTNHNGKGKPILVPRSGAQAKLVA
ATIAASGVDPADIGMIEGHGTATRAGDPLELIALQRTYGAGGSQALLGSAKSNAGHAQAA
AGMIGLIKLLLSGLNGHIPPTLFSDNPTTTVDWNMTGLRLATKLHPWEPKDGTRYGAVSS
FGAGGSNAHAIIAMPACSEEGEDGGDF
>A0A086PST4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii VAND|TrEMBL
MAADLKALAEKAGLRGISNELGIRVLVEAVRNSKTVVTFLAQSFIWKRFVQRFDVVPPFF
SNIEFETASPGAFRVLYSSMTPDELHTYVSNVVLDTARQVLGTSELPALDSPLQELGIDS
LGAVELRNSLSQRLGVKLSATTLFDYPTIRAIIDYIVNQVSGEASAAKATSGALVSAGLA
AGRNSPIAVVGYSCRLPQGSETPDKLWEMLRRAQDCVVEVPLTRFDVDMFYDSDIDAKGK
MYVRKACFMDDADMFDNSFFNISAAEVTYMDPQQRVMLEVAYDAFYSAAYSREHLIGKNY
GVWIGCCNSDWHFLEQQSNPDKSSSYSGPGGSGCLVSNRLSYVFGLKGPSMTIDTACSSS
LVAADCGAQAMRFGYCDGALIGGVNLMLSPQLFLAFCKARMLSPDCRCATFDEKANGYVR
GEGAGAIMLRHLADAQREGKRILGIVRGTAVNHDGRSASLTAPNGPAQQDVIRSALQIGG
VDPLDVALVESHGTGTALGDPIEMGAIKAVYGAGRSADSPLVVGALKSYIGHLEGSSGIA
GILKVLLCLRHHEVPPNLHFDTPNPHMDLSDFHVVLPKKQMKLQPAQKSSTILGSVSSFG
FGGANAHVVFEEYPEPTMATDVGGERRSTEAAESAGKKRLAFLFTGQGSQYPNMCKQLYE
EEPVFRSHMDACFTVLEGKLDVKLRDVIYPTAENDVEMLNLLNQTGYSQPAIFCVEYALA
QLMISKGFSPSVVMGHSLGEYAAAAIAGVMDWKDALLLVHERASIMQHIDPNDGVMYACR
ASEQDAQAAVEKALGEKAVAVTVSAINGPRSIVLAGTQPDVLAVLKAMDMQSRAKQLTVS
HAFHCPLVGEAAALLLPKVESVKLSNPNEGITFISTVTGKAVGAGELTKPEYWATHITKP
VQFLQGMRAAVTSGEAGIFIEIGPRPTLVNMGQQCVPRNDYTWVAPVDPKDSNRNSFPQA
LEKITSNMVCTYTWKRHAFPWTVVVHPFVDKFVPDQDETKATSQKLLTPAVGELLHDHVV
NGTAMMPGVGFLEAMAAGGFMMLDGKLPSTVVALRDCEFERPMLIPKIDPSTGEFTQAAK
LMITVNNKDITLKSIMDGEEEEIFHSRCTFSLCPATSLPTEPADLLTSLQGRITTPVPIT
TLYETLQSVGLQYGARFQSIRECYAAASDEVLAKLRPKLPLHSFERNFRIHPVLLDGALQ
TAAVLFAEMGHKRPLVPVGVKRALLARVPAGSEVWSHVVVKSKDLRSATMDVTLFSTKGT
ILGQLVDVAVRAFDAVAGAQIPKGLLWEVSWVPKAKAPVEDGVDTVENEASETITPTAKL
AVKPTGKVEGLARQPAVNGQPKWLLLKTPSSMLEGLQKALQGTPSAFVKELDEKHPNNAI
SSKIHNSEWDAIIYLGALSAAASSTTCVADALLLANTLGNTAAEKPLPNVLFVTQGQHFI
RECGDVPTTAVPTQTGLYGFCRSAQLELENIIGRPVYLGTLDFAAKDPTLDDPAAFVSAL
QRVLAEADPTGAAGTCEPHTVIRGGKEMVPRLVKSSIECRGAVELHMSDRGALSMLKLRP
MPKSARVPPPRDCVEIRVRAVGLNFRDVLNVMGLYPGDPGPPGADCAGTVVAVGEGVEHL
RVGDAVFGIAQGALKTFVTTSAHLVRPLPGRLTFEQAAALPVVASTVEYALHDVAKVKKG
DKVLIHAVTGGVGLAAVQFCKRVGAEIYGTCSGGKKEEFARSVGVKYITSSRDPKKFAED
MCEFLGNGKHKIDVVLNCLIENYIPETLKFLAPNGRFVELGKRGIWTREQMGTVRPDVLY
ETVAIDTMMEEDPVWFGGMLDRIRNLVDGSMLQPLPLHTFEMTDSSEGGVAAFRFLQRAQ
HIGKVVIRLSSALEVKNFTTNSRQETENEDSGERHTLSPATAVGKPLSQSVADQMHKTYI
ITGGTGGLGLVVAQWLIEEGAHNIVLLSRRGEPPSSVKAGDPVWKYLCGEEQPNCISVTT
LKCDVSQKDDLLRVFKEIESRGLPPVAGIFHAAGVTADAALASQTADSVDQVYLPKAIGA
WNLHDACEALGLNKSLEVFMMFSSVAALLGNFGQANYSAANACLDALAMYRQSLGLCGQS
IQWGPWIEQGMAAQLTQHLEKVGMRGITNELGLRVLGDVMMHPTVAVVGAQSLQWRKFLR
RYAFEMPSFFSLVPMAGAGSSEASVNLATITKEDLCELISSLAQAVSGAAEKPAVDTPLM
DLGLDSLGAVEFRNSVADKVGVKLPQNLMFENPSISSISDYILDKAAGKHGESGVTGTNG
GSGEGSDIPALDTPLDQWLMSVLEPAERFALYIDSFASEYGTLQKMAAEEDIITALEDLG
VEDGGDFERLHVAWDDLCNQINTAKRMAAKDIRPSSTAVSVSDHPKPRMPHPMEDVDTLL
ASLDFDVSTLRPATAPDKVKNVLLTGVTGFVGRVQLASLMQLKQRPDLRVYCLVRARNAD
HALSRIREATKEAKCWQETFVSRIIPVTGDFTQPLLGLSSEEFQELARKIDIVYHTGGDV
NLLSNYGRLRATNVLSVKAIIDLCTTYKVKPLHFASTLGQFPAFFAMFTGHFSGESIRED
STPDVSQMENFYPPSRQGYPWSKWAAERVLEGARKRGLPVAIYRLPNTYVAYKTGYTNKT
DYATALMIASIQEGVFPIGAATAPLTPVDTICDMLVEASFLEKPKHWVYHLFDPRLVTRA
DLEQWSQELGISYVGVKVDEFLEAIKKRGPESPVFKFVPLMQHWRRFWFDPEERTESFPI
SNEHIFEDLPHMRWPSLREVFKNSLLYSVRMGFFPKNSKSIILDPQVALNEARRICGLQL
MGREGEDFFLHPWRVLQESARRECDLLFGGQLAVYRTVRHYFMNVMYLADAQAKCPEIEK
QEIQAPLIIVGLNRTGTTFLQNLMSTDPSNRSLRYCEMIAPYGPDGNYRPKGLPNTEESW
KKDPRIPFAQEILDSQLGLSEEWMAIHTQRAELPEEDFVIFEHCGRCYSICTEFSVPSYR
EWLASDNYKETRKAYSFHKRFLQHLQWQRPAKRWLLKMPFHLFTLEALFETYPDAKIIFM
HRDPKETMGSWASLVKHAQQSLMDNVDPSALGREELRAMSTMINRALAFRRSHPELGPRF
LDVQYQDLVNNPIGVVKSIYKHFGIPLTLAAQTGIASFCNENRKHRDKLTKHMYSLKDVD
LTDGMVQEAFKEYYDSGLCKYLSSAR
>A0A077NPN2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Xenorhabdus bovienii str. feltiae Moldova|TrEMBL
MGNNFTGLEVAIIGMAGQFPGADNIRDYWEMLRDGKEGVSRFTNKILKSNGVSEEYYLNK
NYIPAKGVINKPFHFAADYFGINHSDAKKTDPQIRLMIESCWQALKHANIDTETYPGQIG
VYAGASSQWSWFKALNTEFNSSAEQFHVATLNDLSFCTRISYLLNLRGPSITIQTACSTS
LVAVHTACQALQAGECDVALAGGVSITHPHQSGYLYQEGMINSPDGKTRVFDANACGTVF
SNGVGVVVLKRLSDAIEDNDKIYAVIKGSAVNNDGSDKISFTAPSVLGQQNVIRSALDFA
EVTPDQISYIEAHGTGTLLGDPIEISALNAVFKNSQSCAIGSVKSNVGHCDAAAGILSLI
KSALCVYFKTLVPSIHFEKANPKLELENTPFYVNTETKPWHSSDNELICAGVSAFGVGGT
NAHVVLQEFPIRTETVSVEDLEYEELPNRIEFKPAIAAETTDVLHAEVESDSVFVDDEID
IEGLPQNLLKIFQEYFSNQKISQNDNFFDIGASSLDIVQLHEKINNTYSVNLSISDFYRY
TNCQKMTEKLLGMIGNKSQGQPKKSKITKNRKVLNNKNRTYQDYPEHAIAVVGMSGRFPG
SKNIQEYWNNLLQGKEGISFFTDDELIYAGISAHTLKAKNYIKAKGIVADSLSFDPTAFG
YTARESQYMDPQFRLLHEVTWQVLDDAGYGNPKYRPVTGLFASSGSNHAWLDLLKEEIQD
TTEQFGVALLNDREFLTTRIAYKLNFTGPAVTVQSACSSSALAITLACQSLQINQCDLAL
AGGVSVVTPIKSGYTYAKGMVNSADGHCRPFTQDASGTVFSDGIGMVALKRLDDAIRDND
HIYGVIAGYGVNNDGHEKAGFTAPNADGQAACVKQSLKMASIQASDVEYLEAHGTATQVG
DEVELEGIKDALGVTEINARDCFIGSVKSNIGHTNTASGVASFIKTLLALKHQKIPPSCH
GTENKHTSLENTRFRLTDVAADWVSHGRVRTAGVSSFGIGGTNVHITVQSIEEQPASSQC
QAELITLSSKSREGLVKTMARLGDFLDEEQHSYSLSDIAYTLQVGRGDYDYRTSLVVENV
EALKDALHSLKDSNTLPEALPDQTSGIVFMFPGQGSQYVNMAKDLYQELEIFKTLLDECH
ERLSSQFSIDLIGLLYSGDSEEDSEKLQNTQITQPVIFAISYSLAKTLELLGIEAKAMIG
HSIGEYVAATMAGVMTLDEGLKLVATRGIIMQECEPGVMLSVAAGRDDLEPFLTDKVALA
TVNSPNSCVIAGSQADIEKVQQRLVDKNFRTRLLKTSHAFHTPMMKPGAEKFKAALAEVN
WQKPTKAYISNVTGQWITPSQANSVDYWVEHLCQAVEFHAGIMTCLEKPGLNVFLEVGPG
RTLSTFVKQIAASDANISTFNVMRHPLEAENDRNYLLKLVGQLWMRGSSINWPLLYQNTH
PKRISLPGYQFVGESMAMGTSVLAARGSEKESETKIQKNQISEWLYTEAWEDISLPDEAT
RSDIRVALCFVPDITWCQPLCNSLKLEEKSIKFVLPADAYTSAENVITLVPGDKRHFGKL
IDELKQDALLPDSVIFAWPLSGQSDLETSWFSVITLIQSWTTSGSMTDFRLLLANTKQPE
HTMLNGLVKVITQEVSKCHPRLVQISPLESIERQCEILTEELLATDERFIVNRTQTGRST
LAYHKLRAGLLKENTLLKNEGVYLITGGLGDLGLLFAEYLIKEYGAKVILSGRRVLPSKH
EWKQLASIDHPEAEILQRLDELSELGKGEVAYYSSNVSDKHEMQVLLDAIEEQYGCLHGI
ICAAGVTRGNSFQGINKLTLEDCTPQIETKVEAYKILAELTENKPLDFCLLCSSIASVLG
GLSFSAYSSVSSFADAFAKQQNSQGKPWISVNWDGWVFERNDAGDPIGSSLDQLLIEPDE
GLKILECALQSPLRGQLIISTGDLDKRFEQWVGGHLKPFKLNEFNHSQRAVVSKEQIVGT
IVSVWQDFLKVTNISRDDNFFELGANSLDMVQVNKRLTDALDMDFSVVDMFSYPTSELLA
DFIVNQYGITHDTGEQAEHSDTLNQHRDPSAQLNQSSTPIDRQIAIVGLAGTFPGAENIH
EFWENLTFGKESVTTFSKEELSEEGIDSGLLENPNYIRAKGVFPNAGEFDAEFFGYTPYE
ARQMDPQVRALHTCCWQALQDARIATKDNRAKIGLYASASGNLQWLAQAMATAEGSAGQY
SAMTVADKDYMSTIVSYKLNLTGPSMVLSTACSSSLVAVNEAVKSLRAGECDIALAGGVS
ITLPIKAGYVFEEGMIHSKDGKCRAFDIQASGTVFGDGVGIVVLKPLKQALADNDNIYAT
IIGTAINNDGGMKVGYTAPSTKGQVEVIQSALRDANVMAESIHFVEAHGTGTTLGDPIEF
NALKQAFSTDKKNYCRIGSVKSNIGHLNSAAGIAGLIKATLAVKNRILPPTLHYARPNKE
IDVTNSPFIVNNQYTELNGTRNPIRAGVSSFGIGGTNVHVVLEEAQVSKDKSFNKKVDNR
LPIVLSAPDDKSLQCYKQQLKTFVENNQQQMSVSDIAYSLMQREPMASQFVASACDYDAL
IKALSSGEKDNVKVKPGTTKRKVVFLFPGQGAQYVTMGHELYHSNGLFKEWCDKGFTLAD
KYCSIDLKSLFHSRDEDRNLYNTEFAQPLLFIIEYALAQVLKSYGVTPDAMIGHSLGEYV
AAALAEVFSFEDAIKMICVRGKLMQSTEDAVMLSVMSSSESVKEILTGSLEIALDNSSDL
CVVAGSDSDISSFESDCEAKSIKTKRLRVNKAFHTRYMEPVLGDYAGIIREIAFNKPQIA
FISNVTGKWAETDKVVEYDYWVNHIRQPVRFKESITEVLKEGNCLFIEVGPGHGLSTLAE
NHSDYHANHICISCFDRKNEEINKHSELVQKLGKMALLKIDVNWHAEMADLQPRLVHLPP
TPLRGTKYPTDIKRLQALFSGNKNLGYQADKPEEPVSQSKAGSNPHPKAKRSVIDELSAI
WKLILGVDTIKEDDDFISIGGSSLSAVQVIAKAKSVNLPVNMSMLLSGQTLVQISASLQS
DDETTHKGWQFNEHFSPEMYPGSASCLYSAVREKLKHEHGLTSDDAIMQVVDGSPLLGIG
VQQFENATKIVSKPVNYGTLSGWPSLQECYSFSYDKQFFEDYEAYRHYCESELALGHLVI
VTGSDYYLPFSPSYGLPESEYIKRPLFENIELGDDDIIPHAFVLVGKTPSGYQIYDGSFQ
YFGEITEQEFEKTVIGFKGLDFMQSHEVYNKSRSFMVITVTCAGKFHKDNDLKEQTLNRL
VTDFQTKQAIESNESHLSYYVGLTALDKLIENPGLIASSSNFDLAEIFSRWYQQMLLLRK
FLKISKPEVSTECDHAFSIISEELDKVVACCKNSSDDKTIIDSLLLVKSNLSDIIKNLS
>A0A1Q2ZEB0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MNGVDVALTAGGTDADEIAVVGLSCCLPKAAGPAEFWRLLREGVDATGEAPDDRWAGASH
SPRRGGFLDRIDQFDADFFGISPKEAVAMDPRQRLLLELSWEALEDARIVPTALRGSRTG
VFVGAMGDDYAVLMSRLGQEAIGEHTLTGASRAIIANRVSHFLGLRGPSLTVDTAQSSSL
VAVHMACESLRRGESTVAIAGGVNLNILAETTVSAQKIGALSPDGRCYTFDARANGYARG
EGGVVVVLKKLADAVADGDKIYCVIAGGAVNNEGDGDGDGCGLAVPSRSAQADVIQEAYR
RASVDPAEVQYVELHGTGTKVGDPVEAAALGAALGTRRPAGSPLLVGSAKTNVGHLEGAA
GITGMLKVVLSLRYRLLPPSLNFVAANPDIPLDELRLRVHTRLAEWPEQGRRLVAGVSAF
GMGGTNCHLVLAEAPVRISEGESESAASAVPVPSVVPWVLSGRSESALRGQARRLVEYVE
GDAGLDLVGVGAALVSTRASFEHRAVVLGAGRDELIAGLAGLAAGEPGAGVVAGQGVAGG
RGVVFVFPGQGSQWAGMARGLLVSSPVFAERMRECAQALAPFVEWDLLEVLGDEGALARV
DVVQPVLWAVMVSLARVWESLGVVPAAVVGHSQGEIAAACVAGGLSLGDAAKIISVRSRL
LAESLAGRGGMVAVRLPLAEVELLVARWEGRLSVAAVNGASSVVVSGDAEAVTELVLVGE
AEGFRTRRMDTDCAGHSPHVEEVRAELVEALADIAPVEGSVAFYSTVTGELADTRGLDAE
YWYRNARETVRLADTAGVLTAAGYGVFVEVSPHPVLVPSLEETLFESHSAAVVVTGTLRR
GEDESEQLLVAVGRLHTCGVSVDWSAVVGRGSVVDLPTYAFQRERYWPESVAGPVGVDDE
LWSVVEGSDVGLLSAELGVGEGALGEVVPALAAWRERRRAGSVVEGWRFVESWKLLPGAP
GGVLPGRWLVVVPAGWGEDAWVAGVIGALGAGVVRLEVDEDTDRAALAGRLVDLPELAGV
VSLLGLAEEACSGFGATPVGLAGMVGLVQALGDCGFMAPVWCVTRGAVSVGSADPVGSPV
QTALWGLGRSAALDLPVRWGGLVDLPVAVDERIGGLLRRVLTGDEDQVAVRESGVYGRRL
VRAGAGGGVAGAGVRLSGSVLITGGTGGLGGHVARWAVARGAEHVVLVSRRGLEAPGASG
LREELMALGARVTVEACDVADREALAGVLGRVPAEFPLTAVVHAAGVGDGHVPVGELELE
RLDGVLRAKMVSAWHLHELTAGLGLQAFVLFSSGAASWGAGGQAAYAAANAFLDGLAGYR
HGAGLAATSIAWGLWAGPGMGAADVEGYRQRGVLAMEPELAMAALERAVGEGSVTLTVTD
TDWERFAPSFTVERPSALLSGIPEARKALARPGGESALRRRLAGLGERERARALLDLVRR
EAAVTLGFDNADALPDGRAFRDIGFSSLTEVELRNKLASATGLALPASLVFDYPTPAVLA
EHLGSELLGSEAQVVVPVVVKAEPDEPIAIVGMGCRFPGGVSSPSDLWALLAGGVDAISA
FPTQRGWDVVGDGFARVGGFVEDVAGFDAGFFGISPREALAMDPQQRLLLETAWEALERS
GIDPNLLKGSRTGVFVGGTDSSYDTVGEASAELDGYRLTGGSSSVLSGRIAYVLGLEGPA
VTVDTACSSSLVALHLAVQALRSGECSMALAGGVTVMATPEVFAQFAAQDGLARDGRCKA
FAASADGTGWGEGVGLLVVERLSDAQCNGHQVLAVVRGSAVNQDGASNGLSAPNGPSQQR
VIRQALASAGVAAAEVDVVEAHGTGTRLGDPIEAQALLATYGQDRPEDRPLWLGSLKSNI
GHTQAAAGVAGVIKMVLAMQQGVLPRTLHVDEPSPEVDWSVGAVELLTEQRSWPVVDRPW
RAGVSSFGVSGTNAHVILEQAPEVEPAVRVEVVPSVVPWVLSARSELALREQARRLAAYV
EADSGLDPVDVGAGLVSTRASFEHRAVVLGTGRDELIAGLAGLASGELGAGVVTGEVGQS
VAGEQGVVFVFPGQGSQWVGMARGLLVSSPVFAERMGECARALAPFVEWDLLEVLGDEEA
LGRVDVVQPVLWAVMVSLAQVWRSFGVVPAAVVGHSQGEIAAACVAGGLSLDDAARISAV
RSRMIAGSLAGRGGMVSVGLPRAEVELLIVRWEGRLSVAAVNGPSSVVVSGDPEALAELV
VAGEAENFRARKIEVDYASHSAHVEEIEAELVEALADIAPVEGTVAFYSTVTGELTDTRD
LDAEYWYRNLRETVRLADTTRALAAAGHGTFVEVSPHPVLTPSLEETLFESHPSAVVTGT
LRRGENELEQLLAAAARLHTRGVPVDWSAVVGRGSVVDLPTYAFQRERYWPRPRAAAGDV
RGAGLVSLSHPLLGAAVELAGGEGVVFTSRLSLASHDWLADYLVNGVVVVPGTAFVELLV
RAGDEVGCGVLEDLALERPLVLSERGAVQVQVVVGAPAESGRRAVSVYSRPEETAAEAGW
TRHASGALASESTMPSGAELTVWPPAGAEPVPVDDLYDGLADAGYGYGPAFQGLRAAWRR
GEEVFAEVRLPGEVTDRAGEFGIHPALFDAALHAAVFLPGDVEGGLPFAWSGVSLHASGA
QSLRVRLSVAGDGGLCLNAVDDTGAPVVSVDSLTLRPVWSELLGSGDERRSLFGVDWVVL
PGVGDEASAGSWAVIGAGELEVESLGVPCYAGVGDLVGAGVPVPDVVVVACVGSLEGDRG
VDARVLTGRVLGVVGEALAEDRLSGSRLVVVTCGAVAAGVGRDVSDLAGGAVWGLVRSAM
SEHPGRLVLADVESFVADVPVVVGLVGGDEPEFAVRGGRVLVRRLARPDAGALTLPAGDG
WRLGAEIVGTPDGLAFVPDVGGAAELADGQVRVEVRAAGVNFRDVLVALGVVSADALGLG
GEGAGVVTEVGPGVTGLVPGDRVMGVLADAFAPVVVADHRTLVPVPEGWSFTDAAAVPVV
FATAWYGLVDVAGARPGERVLIHSAAGGVGMAAVGIARHLGLEVFATADPAKHDALVAMG
VAPDHIASSRSAEFADRFAVVDVVLNSLTGELVDASLRLLRDGGRFVELGKTDVRDADAV
AAEHPGVRYEAFDLLPAAGPERLGRILVECVGLLAEGVLSRLPVMVRDLRQAPEVFRFMS
RGEHVGKIVLRVPGGFVGDGTVLITGGTGTLGGLLARHLADRHGVRHLTLVSRQGMAAPG
ARELVGELAGLGAEVRVVACDVSDRDAVAELVAGVPVERPLTAVIHTAGVLDDGTITSLT
PERIDTVMRPKADAAWYLHEATAGLDLAAFVLFSSFAATCGAPGQGNYAAANAFLDALAL
HRHALGLPATSLAWGWWADASGMTGGLGQSDHVRLGRAGVRAMPAAEGLALFDLACRRPE
AYLVPVRLELPRHNEPVPPLLRGLVTGGRARPVARAGVRDGSGLAGRLAGLTAADQQRLL
LDLVCGHVATVLGHVSAGVVDPEKALRDMGFDSLTTVELRNRLATATGLRLPATLVFDHP
TVSRLATYLRQQLTGAVEAAPVAPVVVKAEPDEPIAIVGMGCRFPGGLSSPEQLWDAVMS
SADVVGEFPADRGWDLVGDGFARLGGFVEDVAGFDAEFFGISPREALAMDPQQRLLLETA
WEALERSGIDPNALKGSRTGVFVGGAGFGYDTVGEASDELDGYRLTGGADSVLSGRIAYV
LGLEGPAITVDTACSSSLVALHLAVQALRSGECDLALAGGATVMSAPRIFAEFAVQDGLA
ADGRCKAFAASADGVGLAEGAGLVAVERLSDARRNGHRVLAVVRGSAINQDGASNGLAAP
SGPSQQRVIRQALASAGVAAAEVDVVEAHGTGTRLGDPIEAQALLATYGQDRPEDRPLWL
GSLKSNIGHTQGASGVAGVIKMVLAMQHGQLPRTLHVDQPSTEVDWSVGAVELLTEQRPW
PVVDRPWRAGVSSFGISGTNAHLILEQAPEVEPASDVDVVAPVVVPWVLSARSELALREQ
ARRLAAHAEADPGLDPVGVGAALVSTRASLEHRAVVLGTDRDQLIARLAGLAAGEPGAGV
VTGRAGQSTAGGRGVVFVFPGQGSQWAGMAQGLLTASPVFAERMGECARALAPFVEWDLL
EVLGDQEALERVDVVQPVLWAVMVSLAQVWQSLGVTPAAVVGHSQGEIAAACVAGGLSLD
DAARIVAVRSRLLARSLSGHGGMVSVRLPLVEVESLIARWEGRLSVAAVNGLSWVVVSGD
AEAVTELVMASEAEDFRARRMDTDCAGHSAQVDEIRAELVEALADIAPVEGSVAFYSTVT
GELTDPRELDAEYWYRNLRETVRLAETTPVLATAGYGVFVEVSPHPVLVPSLEETLFEPH
PAAVVTGSLRRDENELEQLLTALSTLHTHGVPVDWSAVVGRGSTVELPTYAFQRERYWPR
PRAVAGDARGAGLVSVGHPLLGAAVELAGGEGVVFTSRLSLASHDWLADYTVNGVVVVPG
TVFVELLVRAGDEVGCGVLEDLALERPLVLPERGAVQVQVQVVVGAPEESGRRAVSVYSR
PEETGAEAGWIQHASGTLVSESTMPGVEFTVWPPAGAEPVPVDDLYDGLAETGYGYGPVF
QGVQAVWRRGGEVFAEVRLPDEVAEQAGEFGIHPALFDAALHAAVFLPGDVEGGLPFAWS
GVSLHASGARSLRVQLSATDDGALCLDAADDTGAPVLSVDSLTLRPLRAELLEPGDEQRS
LSSLPRHGGRARPVARVGVRDGSGLAGRLAGLTVADQQRLLLDLVCGHVATVLGHASAGA
VDAEKALRDMGFDSLTTVELRNRLAAATGLRLPATLAFDHPTASRLATHLRQQLLGTVEA
APVVPVVVKAEPDESIAIVGMGCRFPGGVSSPSDLWALLAGGVDAISAFPTQRGWDLVGD
GFARVGGFLHEAAEFDAEFFGISPREALAMDPQQRLLLETAWEALERAGIDPDVLKGSRT
GVFVGGAGSGYEAVGGASDELDGYRLTGGAGSVLSGRIAYTLGLEGPAVTVDTACSSSLV
ALHWAAQALRAGECDLALAGGVTVMATPGVFAEFAIQGGLAADGRCKAFAAAADGTGWAE
GVGLVAVERLSDARRNGHRVLAVVRGSAVNQDGASNGLSAPNGPSQQRVIRQALASAGLT
AAEVDVVEAHGTGTRLGDPIEAQALLATYGQGRPADRPLWLGSLKSNIGHTQGAAGVAGV
IKMVLAMQQGVLPRTLHVDEPSPEVDWSAGAVELLTEQRSWPVVDRPWRAGVSSFGVSGT
NAHLILEQAPEFEPVSDVVVVPSVVPWVLSAGSGSALREQARRLAAHVEADSGLDLVGVG
AALVSTRASLGHRAVVLGADRDELIAGLAGLAAGEPGAGVVAGVSVAGGRTAFLFTGQGA
QRVGMGRELVAEFPVFAEAFGEICAGFGGLLPGSLEEVVFGGDEYRLTETGWAQPALFAF
EVAMFRLLGSWGVAPDFVVGHSVGELAAAYVAGVWLLPDACRVVAARAGLMQALPAEGVM
LAVEATEAEIVSVAGEVAGWGERAAIAAVNAARSVVLSGDAGVVGAMGELWSGRGRKVRR
LRVSHAFHSPLMDPMLDAFADVLGGVEFNEPSTGMTVPAAQVCSVEYWVRQVREPVRYAD
MLTELSTQGVTRFVEVGPDGVLSGLGSGAVDGVFVAAQRRDRPEVHTAMTALSTLHTHGV
PVNWSAIVGRGSTVDLPTYAFQRERYWPRSRAVAGDVRGAGLTSVGHPLLGAAVELAGGE
GVVFTSRLSLASHDWLADHAVRGVVVVPGTAFVELVVRAGDEVGCGVLEDLALERPLVLS
ERGAVQVQVVVGAPAESGRRAVSVYSRPEETAAEAGWTRHASGTLTSESTMPTGAELTVW
PPAGAEPVPVDDLYDGLADAGYGYGPAFQGLRAAWRRGEEVFAEVRLPDEAAERAGEFGI
HPALFDAALHAAVFLPGDVEGGLPFAWGGVSLHASGARSLRVRLSVIGDGALRLSAVDDT
GAPVVSVESVELRPVWSELLEAGDERRSLFGVDWTVLSGVGDEVPAGSWAVVGADGPGLE
SLGVPCYAGVGDLVGSGVPVPDVLVVACVGSLEGDRGVGARVLTGRVLGVVRQVLAEERL
GGSRLLVVTCGAVAAGVGEGVSDLAGGAVWGLVRSAMSEHPGRLVLADVESFVGDVPVVV
GLVGGDEPEFAVRGGRVLVRRLTRPDAEALTLPVSDGLVGDGTVLITGGTGTLGGLLARH
LADRHGVRHLTLVSRQGIAAPGARELVGELAGLGAEVRVVACDVSDRDAVAELVAGVPQE
RPLTAVIHTAGVLDDGTITSLTPERIDTVMRPKADAAWYLHEATAGLDLAAFVLFSSFAA
TCGAPGQGNYAAANAFLDGLALHRHAQGLPATSLAWGWWADASGMTEGLGQSDHVRLGRA
GVRAMPAAEGLALFDLACRRPEAYLVPVRLELSRHNELVPPLLRGLVAGGRARPIARAGV
RDGSGLAERLAGLTADDQQRLLLDLVCGHVATVLGHASAGVVDPEKALRDMGFDSLTTVE
LRNRLAAVTGLQLPATLAFDHPTASRLAGYLHTRLAPTADADSAEARLREALASIPLTRL
RDAGLMDVLLRLAGASEDAPTNTEKQLDEMDAAALIDFVLDERN
>A0A100J439|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MTVSQDRLLEALRESVKETERLRRRNAELTTPEPIAVVGMACRYPGGVASPEDLWRLVSG
GVDAISEFPDDRGWSLDTLDDSDPDHHDTSYTRHGGFLYNAAEFDAGFFGISPREALAMD
PQQRLLLETAWEALERSGIDPHALKGSRTGVFVGGAVSGYDTVGDASGDAEGYTLIGGAS
SVLSGRIAYTLGLEGPAVTVDTACSSSLVALHLAAQALRSGECSMALAGGVAVMATSGIF
GGFATYGGLAGDGRCKAFAAAADGTGWGEGAGLLVVERLSDARRNGHRVLAVVRGSAINQ
DGASNGLTAPNGPSQQRVIRQALASAGLTAAEVDVVEAHGTGTRLGDPIEAQALLETYGQ
GRPEDRPLWLGSVKSNIGHTLAAAGVAGVIKMVLAMQQGVLPPTLHVGEPTPEVDWSSGA
VELLTEQRSWPVVDRPWRAGVSSFGVSGTNAHVILEQAPEVEPASDVDVVAPVVSPVVVP
WVLSARSELALREQARRLAAHVEADPGLDPVDVGAALVSTRASLEHRAVVLGADRDELIA
RLAGLAAGEPGAGVVAGQSVAGGRGVVFVFPGQGSQWVGMAQGLLVSSPVFAERMAECAR
ALAPFVEWDLLEVLGDEGALGRVDVVQPVLWAVMVSLARVWQSLGVTPAAVVGHSQGEIA
AACVAGGLSLTDAARISAVRSRMIAGSLAGRGGMVSVGLPRAEAELLIARWEGRLSVAAV
NGPSSVVVSGDPEALTELVVAGEAENFRARRIEVDYASHSAHVEEIEAELVEALADIVPV
EGAVAFYSTVTGEVIDTRELDAGYWYRNLRETVRLADTTRALAAAGHGTFVEVSPHPVLT
PSLEETLFESHPAAVVTGTLRRGENEPEQLLAAAARLHTRGVRVEWAEIVGRGSAIDLPT
YAFQRERYWPESVSGSVVAGVDDELWSVVEGADVGLLSAELGVGEGALGEVVPALAVWRE
RRRAGSRVEGWRFAESWKLLPGALGGVLPGSWLVVVPVGWGEDVWVAGVIGALGAGVVRL
EVDGDTDRAVLADLPELAGVVSLLGVAEQACPGFGATPVGLAGTVGLVQALGDCGITARV
WCVTRGAVSVGSADPVGSPVQTALWGLGRSAALDLPVRWGGLVDLPVVFDEQAGGLLRRV
LTGDEDQVAVRESGVYGRRLVRAGSGGAAGAGVRLSGSVLITGGTGGLGGHVARWAVARG
AEHVVLVSRRGLEAPGAVGLREELEALGARVTVEACDVADREALAAVLGAIPGEFPLTAV
LHAAGIGDGHVPVGELELGRLDGVLRAKMVSAWHLHELTAGLELQAFVLFSSGAASWGAG
GQAAYAAANAFLDGLAGYRHGAGLAATSIAWGLWAGPGMGAAGAEFVEGYRRRGVFPMEP
GLAMAALERAVGDGSVTLTVTNTDWETFAPSFTVERPSALLSGIPEVRKALALSGVQPGG
ESALRRRLAGLGERERARALLDLVRREAAVTLGFDNADALPDGRAFRDVGFDSLTAVELR
NKLASATGLVLPASLVFDYPTPAVLAEHLGSELLGSEAQVVAPAVVKAEPDEPIAIVGMG
CRFPGGVSSPEQLWDVVASSADVVGEFPGDRGWDLTGADFARVGGFVEDVAGFDAGFFGI
SPREALAMDPQQRLLLETAWEALERAGIDPDVLKGSRTGVFVGGTVSGYEAVGGASGDAE
GYMLTGGAGSVLSGRIAYTLGLEGPAVTVDTACSSSLVALHLAAQALRSGECSMALAGGV
TVMATPRGFAEFAIQGGLAADGRCKPFAAAADGTGWGEGVGLLVVERLSDARRNGHQVLA
VVRGSAINQDGASNGLSAPNGPSQQRVIRQALASAGVAAAEVDVVEAHGTGTRLGDPIEA
QALLATYGQDRPEDRPLWLGSVKSNIGHTQAASGVAGVIKMVLAMQQGVLPRTLHVDEPT
PEVDWSVGAVELLTEQRSWPVVDRPWRAGVSSFGVSGTNAHLILEQAPELEPASGMEVEP
VVVPSVVPWVLSARSESALREQARRLAAHVEADPGLDPVDVGAALVSTRANLGHRAVVLG
ADREQLIAGLAGLAAGEPGAGVLTGVSVAGGRTAFLFTGQGAQRVGMGRELAAEFPVFAE
AFGEISAGFEGLLPGSLEEVVFGGDEYRLTETGWAQPALFAFEVAMFRLLGSWGVAPDFV
VGHSVGELAAAYVAGVWSLPDACRVVAARAGLMQALPAEGVMLAVEASEAEITSVAGEVA
GWGERAAIAAVNAARSVVLSGDAAVVGAMGELWSGRGRKVRRLRVSHAFHSPLMDPMLGA
FADVLGGVEFNEPSVGMTVPAAQVCSPQYWVRQVREPVRYADMLTELSTQGVTRFVEVGP
DGVLSGLGSGAVDGVFVAAQRRDRPEVHTAMTALSTLHTHGVPVDWPAIVGRGSAVELPT
YAFQRERYWPEAVAGPVVAGADDELWSVVEGADAGLLSAELGVGEQALAEVVPALAAWRE
RRRSRFAVEGWRFAESWKLLPGAPGGALPGSWLVVVPVGWGEDAWVASVVGALGVGVVRL
EVAGDADRTVLAAVLADLPELAGVVSLLGVAEQACPGFGATPVGLAGTVGLVQALGDCGI
TARVWCVTRGAVSVGSADPVGSPVQTALWGLGRSAALDLPVRWGGLVDLPVAVDERIGGL
LRRVLTGDEDQVAVRESGVYGRRLVRAGSSGAAGAEARLNGSVLITGGTGGLGGHVARWA
VARGAEHVVLVSRRGEQADGVSGLREELIAQGARVTVEACDVADREALAGVLARVPADCP
LTAVVHAAGIGDGHVPVGELELGRLDGVLRAKMVSAWHLHELTAGLGLEAFVLFSSGAAS
WGAGGQAAYAAANAFLDGLAGYRHGAGLAATSIAWGLWAGPGMGAAGAEFVEGYRRRGVL
AMEPGLAMAALERAVGDGSVTLTVTNTDWETFAPSFTVERPSALLSGIPEVRKALALPGA
GSVGESALRSRLAGLGERERTRALLDLVRREAAITLGFDNADALPQGRAFRDVGFDSLTA
VELRNKLASATGLVLPASLVFDYPTPAVLAEHLGSELLGTVEAVSVMPVTTVAVDEPIAI
VGMGCRFPGGVESPEQLWALLAGGVDAVSAFPTQRGWDLVGDGFARVGGFLYEAAEFDAG
FFGISPREALAMDPQQRLLLETAWEALERTGIDPNTLKGSRTGVFVGGTGSGYDTVGGAS
GDAEGYMLTGGAGSVLSGRIAYTLGLEGPAVTVDTACSSSLVALHWAAQALRSGECDLAL
AGGVAVMATPGIFAEFAVQGGLAGDGRCKAFAASADGTGWGEGVGLLVVERLSDARRNGH
QVLAVVRGSAINQDGASNGLAAPNGPSQQRVIRQALASAGVTAAEVDVVEAHGTGTRLGD
PIEAQALLATYGQDRPEGRPLWLGSVKSNIGHTLAAAGVAGVIKMVLAMRHGQLPPTLHV
DEPTPEVDWSAGAVELLTEQQPWPVVDRPWRAGVSSFGISGTNAHVILEQAPELEPAADA
VAVPSVVPWVLSGRSESALREQARRLAAHVEADPGLDSVGVGAALVSTRAELEHRAVVLG
AGRDELIAGLAGLASGEPGAGVVTGRAGQSVAGEQGVVFVFPGQGSQWVGMAQGLLVSSP
VFAERMAECAQALAPFVEWNLLEVLGDEEALGRVDVVQPVLWAVMVSLAQVWQSLGVTPA
AVMGHSQGEIAAACVAGGLSLADAARISAVRSRLLAKSLAGRGGMVSVGLPRAEAESLIA
RWEGRLSVAAVNGPSSVVVSGDPEALAQLVVAGGEENFRARKIEVDYASHSAHVEEIRAE
LVEALADIVPVEGTVAFYSTVTGELTDTRDLDAGYWYRNLRETVRLADTTRALAAAGHGT
FVEVSPHPVLTPSLEETLFESHPSAVVTGTLRRGENELEQLLAAAARLHTRGVPVDWSEI
VGRGSVVELPTYAFQRERYWPRPRAVAGDVRGAGLTSVGHPLLGAAVELAGGEGVVFTSR
LSLTSHAWLADHTARGVVLLAGTAFVELVVRAGDEVGCGVLEDLALERPLVLSEREAVQV
QVVVEAPAESGRRAVSVYSRLEETGTEAGWTRHASGTLTSEQTMPSGAELTVWPPAGAEP
VPVDDLYNGLAEAGYGYGPSFQGLRAAWRRGEEVFAEVRLPDEVADSAGEFGIHPALFDA
ALHAAAFLPAGGEGGLPFSWSGVSLHASGAQSLRVRLSVAGDGGLCLNAADDTGAPVVSV
DSLVVRPAPQGQLSSPGSGQDNLFSVDWIVKPESGGSLPRCVVAGAGGQDLAAMLGVPWH
SELSECQDADLVLLPTGAGADGGDVVAAARSEVCRVLGLVQQWLADERGDTRLVVVTRGA
VSTGTGDRVEDVAGAGVQGLVRSARSEHPGRFGLVDVDGSAESWQCLPAVLNGTADDEDG
FELAVRAGQAYTPRLTPTRTREVLAAPEGVEAWRLGMAGQGSVDDLVIVPSPEAEVPLEA
GQVRIGVRAAGLNFRDVLNMYPGEVPVLGAEVAGVVLEAGPGVTGFLPGDRVMGMAVGGF
GPVVVADARLIVPFPQGWSFVQAAGVPVVFLTALHGLRETGRLTAGQRVLVHAAAGGVGM
AAVQLARLWGAEVFATASPGKQDTVCGLGVARDHIASSRTTEFADRFTGMDVVLNSLAGE
FIDASLNVLRAGGRFVELGKTDLRDTDAIATTHPEVNYQAIDLTDFSPDMVGGMLAELAE
LFESGVLSPLPTRTWDVRQSRDAFRYMAQARHVGKIVLTVPQQLDPDRTVLITGGTGGLG
GLLARHLIDRHGIRHLTLVSRQGITAPGARELVEELTGLGAEVRVVACDVSDRNAVAELV
AGVPQQHPLTAVIHAAAVLDDGTITSLTPERIDTVMRPKADAAWYLHEATAGLDLATFIL
FSSVAGVFGGAGVAGYAAANSVLDAMAQQCAARGEPVVSLAWGLWGDAGGMMGRLGQTDL
VRFGRAGVRAMPAAEGLALFDLACRRPEAHLAPVGLELSRHNEPVLPLLRGLVSAGGRAR
PVARAGVQDGSGLAGRLAGLTADDQQRLLLDLVRGHVAPVLGHASAQDIEPDKAFRDMGF
DSLTTVELRNRLATATGLRLPATLAFDHPTASRLATHLRQRLTDTVEAVSVTPVTTATVD
EPIAIVGMGCRFPGGVESPEQLWTLLTGGIDATSAFPTQRGWDLTGDGFAQMGGFLHEAA
EFDAGFFGISPREALAMDPQQRLLLETAWEALERTGIDPNALKGSKTGVFMGGTGSGYDT
VGGTAGDAEGYTLTGGASSVLSGRIAYVLGLEGPAVTVDTACSSSLVALHLAAQALRSGE
CDLALAGGVTVMATPGVFAGFAMQGGLASDGRCKAFSVTADGVGLAEGAGLLAVERLSDA
RRNGHRVLAVVRGSAMNQDGASNGLTAPNGPSQQRVIRQALASAGVTAAEVDVVEAHGTG
TRLGDPIEAQALLETYGQGRPADRPLWLGSLKSNIGHTQAAAGVAGVIKMVLAMRYGQLP
PTLHVDEPTPEVDWSAGAVELLTEQQQWPVVDRPWRAGVSSFGISGTNAHVILEQAPELE
PASDAVVVPSVVPWVLSARSELALREQAWRLAAHVEADPGLDPVEVGAALVSTRASLGHR
AVVLGTGRDELIAGLTGLAAGEPGAGVVTGVAGSGGRTAFLFTGQGAQRLGMGRELVAEF
PVFAEAFGEVCDGFAGLLPGSLEEVVFGADEHRLTETGWAQPALFAFEVAMFRLLSSWGV
APDFVVGHSVGELAAAYVAGVWSLSDACRVVAARAGLMQALPAEGVMLAVEATEAEIASA
AGEVAGWGERAAIAAVNAARSVVLSGDAGVVGAMGELWSGRGRKVRRLRVSHAFHSPLMD
PMLDAFADVLGQVEFNEPSVGMTVPAAQVCSPQYWVRQVREPVRYADMLTELGVQGVTRF
VEVGPDGVLSGLGSGAVDGLFVAAQRRDRPEVHTAMTALSTLHTHSVPVNWSAIVGRGSA
VELPTYAFQRERYWPRSRAVAGDVRSAGLVSVGHPLLGAAVELAGGEGVVFTSRLSLASH
DWLADHAVRGVVIVPGTAFVELLVRAGDEVGCGVLEDLALERPLVLPERGAVQVQVVVGA
PAELGRRAVSVYSRPEETAAEAVWTQHASGTLAAAGVPAPVWQDVAWPPAGAEPVPVDGL
YDGLAEAGYGYGPAFQGLRAVWRRGEEVFAEVRLPGEVADRAGEFGIHPALFDAALHAAV
FLPGDVEGGLPFAWSGVSLHASGARSLRVQLSVIGDGALRLNAADDTGAPVLSVDSLTLR
SVRAELLESGSGQDNLFSVDWIVKPESGGSLPRCVVAGAGGQDLAKMLGVAWYPELSECQ
DADLVFLPTGAGADGGDVVAAARSEVCRVLELVQQWLADERGDTRLVVVTRNAVSTGTGD
RVEDVAGAGVQGLVRSARSEHPGRFGLVDVDGSAESWQCLPAVLNGTADDEDGFELAVRT
GQAYTPRLAPASVGEAPEARPVDPEGTVLITGGTGTLGGLVARDWVERHGVRHLLLVSRQ
GTAAPGARELVEELTGLDAQVRVVACDVSDRAALTAVLDAIPDEHPLTAVVHTAGVVDDG
MVTSLTPARVDAVMRPKADAAWYLHEATAGLDLAAFVLFSSTSGVLGAAGQAGYAAANSV
LDAIAQQRAARGEAAVSVAWGMWAPASALTGQLSQTDRRRISATGVVPLTAEEGMVLLDR
AVRSGRSFVAGMRWDPAGVRSGQPLSGLLRGLVRGPVRRRSLATERDGEAAGAALRQRLA
GLSAADAHAVLAQVVTTHTATVLGHATPESIQATSAFQELGFDSMTAVDLRNRLNTVTGL
RLPATLVFDYPTPDTVAGHLRSELRPDILAAEPSGDTDARLGETLATIPVSRLRKAGLLD
LLLQLAGEDGEVAQNTTSDDEISIDELDGESLLRLAAENTTN
>A0A060Q3K2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia brasiliensis|TrEMBL
MNTSVDELVEALRESLKENERLKARISEPIAIIGMACRFPGGVSSPEDLWDLLAADGDAI
APFPTDRGWDTDTLYHPDPEHPGTTYVREGGFLRDAALFDAGFFGITPREAAAINPQQRL
LLECAWESLERAAIDPTTLVGSRTGVFAGVIYQDYSVPLQAPPNDAEGYLLTGELGSVAS
GRIAYTLGLQGPAVTIDTACSSSLVALHAAAASLRRGECSLALAGGATVMCHPRVITEMS
RQGGLAPDGRSKPFSDNADGAGWGEGVGMLVLERLSDAHANGHAILAVLRGSAINSDGAS
NGLTAPNGPAQQRVIRDALHACDLSPAEVDAVEAHGTGTSLGDPIEAGALIAAYGAGRPA
QRPLWVGSVKSNIGHPQAAAGVAGVIKMVLALRHETLPALVHFTTPSRHVDWAEAGVRPL
AEAVPWPRGERVRRCGVSSFGISGTNAHVILEEAPVATPDTGSSGPPAEVTPWVVTARSA
AALPAQAAALRTAAATERPEDVGFSLALNRSRFDHRAVVVGTDRDELLTGLTALSRDEAA
PQVVRGTAWPDPRPVFVFPGQGGQWPEMAAALLKSSPVFAQSLAECADALARYVPWSLHD
VLDNAAGAPSLDRVDVVQPVLWAVMVALARVWQAYGVEPAAVVGHSQGEIAAACVAGALS
LDDGALIVTRRSRAVLPLSGTGAMLSLGLGAAAARERMARFGTRLSVAAANGPESTVVCG
EPDAIAELQAECAAAGVHTRTINADYASHSSHVDPIEAELLDALARVRPRAGSVPMISTV
TGAPIEHTALDANYWWQNLRRPVEFESATRHLLTAGHHVFVEISPHPVLAFGIESTIEAT
RAEAAVVATLRRDDGGFDRMTAALAQAHAYGVHVDWDAYFAPTRPRRIPLPTYAFQRQRY
WLTEAPHTGPADLTAAGLERPAHPLIGAGVQLADTEGHLFTASLSLDSQPWLADHTVGGE
AILPGTAMVELALRAGEQVGAEWVDELVLEAPLVLPGDDTVQVQLTVGAVDDTGGRRVSL
YSRRGGLGAWTRHAHGTVSPTWEPPADGFAEWPPTDAAPMNVDAVYDRAAQAGMAYGPAF
RGLDRLWRRGDEYYLESRLPNEIASDAGQYGLHPALTDAVLHGCLAAMADRNALTHAAVL
PFTWTGVGLYTLGAAAVRARITALGDTEFRVDLADDAGAAVGQIATLSFRPAGSLLQGAT
QALSTVRWTSLAAPADTGTSDELWVLGDDLGHRLADAGVEFGRCTDATAAGTSSPVLLDV
APATTADGVARAALDVVRRVLSDIRAWLAATGDPAARLAVVTHRAVATTPDEDVTDLASA
AVWGLIRTAQAEYPGRFVLVDLDDEPASARALPPALRTAEEQIAIRDGHLSTPRIGPLRT
EATAPPLADPAQTVLITGGTGGLGGLLARHLVTVHHVRHLLLVSRRGETSPGAAELVAEL
NALGAEVRVAACDIADYAATADLLRSLPADRPLGAVIHAAGVLDDGTVETLTDAQIERVM
RAKVDGAVNLHLLTEDLGLSGFLTYSSVAGVLGTPGQANYAAGNAFLDALVQHRRAHGLP
GISLAWGPWASDAGMTEGLSEVDHARLGRWGLLPLDAADGCALFDAARAADRPLAIPCRI
QLTRSGDAQLIPAMLRDMVRAAPRLRQATSAPKADDTARERERLRDHLIGLPAAQRRAEL
VRIVTRHAAEVANLASADEVAADLPLMALGFDSLASLELRNRLVHQLGLTGHLSANAVFQ
TPTPTGLAARIATILTGDDESAAVDEPAPDQVRLPDDIGPATTSGPVTLAAAAHLFVTGA
TGFVGSFLVRELLDRTSATVHCLVESPSAPAGLARLQDTMRGYRLWDDALAERLIAVPGT
LTDPHLGLTEAAFDALARTVDGVFHCAAVVDESESADGMAAALRLAARHRTVPVHHLSTF
AVFGQQDTEAPALTEDAPTGPSDALTGEHARSRWIAEEMVSRARDRGLPVSVYRLPRVFG
HRETGACSPTDLLWRVVQGCVQAGVAPATELTADLIPVDYAAKAVAALACDGGAAGATFH
LSNPEPVPFASIVAALVARGYPLAELPAGLWADMIGSDPDNAAHPVLQAFSEIAFEQPGH
GRSSFESTATRAALTAVGVSGPPASAAALGATIDYFIETGHLPAAQEASTR
>A0A653FNY3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium smegmatis|TrEMBL
MSSGEDPVVIVGMALEAPGGVTTADDYWTLLTEEREALGRFPRDRGWDIGALFDGSRRDG
FKPINDLGGFLSGAGEFDPAFFGISPREAVAMDPQQRVALRVAWRALENSGINPDDLAGH
DAGCYIGASGLEYGPPLSEFSHHSGHLITGTSLGVIAGRIAYTLDLAGPAVTVDTSCSSA
LTALHTAVGALRAGDCDLAVTGAVCVMGSPGYFVEFSKQHALSDDGRCRPYSAHASGTVW
AEGAAMFVLQRRSAAVRDGRRILAEIRATALNQDGRTTGLTAPSGAAQERLFRKAIDRAG
IRPEDVGMIEGHGTGTRLGDRTELRSLAQTYGATAPGAGAVLGSVKSNVGHAQAAAGGLG
LAKVLLAGQRAAIPATLHVDQPSGEIDWDAQGLRLATKLTPWPAVDGERIAAVSAFGMSG
TNAHAIVAIPEAA
>D9UBQ1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces pristinaespiralis|TrEMBL
MTTLVSADSIRDELRTHLAAILYCEIEEIDDDATFAELGLDSVLGVELVSLLNTKYGLEE
MLDTVYAHPTVNQLSTYVSSQVAALGATAK
>A0A077Q7N9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Xenorhabdus bovienii str. Intermedium|TrEMBL
MGNNFTGLEVAIIGMAGQFPGADNIRDYWEMLRDGKEGVSRFTNEILKSNGVSEEYYLNK
NYIPAKGVINKPFHFAADYFGINHSDAKKTDPQIRLMIESCWQALKHANIDTETYPGQIG
VYAGASSQWSWFKALNTEFNSSAEQFHVATLNDLSFCTRISYLLNLRGPSITIQTACSTS
LVAVHTACQALQAGECDVALAGGVSITHPHQSGYLYQEGMINSPDGKTRVFDANACGTVF
SNGVGVVVLKRLSDAIEDNDKIYAVIKGSAVNNDGSDKISFTAPSVLGQQNVIRSALDFA
EVTPDQISYIEAHGTGTLLGDPIEISALNAVFKDIQSCAIGSVKSNVGHCDAAAGVLSLI
KSALCVYFKTLVPSIHFEKANPKLELENTPFYVNTETKPWHSSDNELICAGVSAFGVGGT
NAHVVLQEFPMRTETVSVEDLEYEELPNRIEFKPAIAAETTDVLHAEVESDSVFVDDEID
IEGLPQNLLKIFQEYFSNQKISQNDNFFDIGASSLDIVQLHEKINNTYSVNLSISDFYRY
TNCQKMTEKLLGMIGNKSQGQPKKSKVTKKRKVLNNKNRTDQDYPEHAIAVVGMSGRFPG
SKNIQEYWDNLLQGKEGISFFTDDELIDAGISAHTLKAKNYIKAKGIVADSLSFDPTAFG
YTARESQYMDPQFRLLHEVTWQVLDDAGYGNPKYRPVTGLFASSGSNHAWLDLLKEEIQD
TTEQFGVALLNDREFLTTRIAYKLNLTGPAVTVQSACSSSALAITLACQSLQINQCDLAL
AGGVSVVTPIKSGYTYAKGMVNSADGHCRPFTQDASGTVFSDGIGMVALKRLDDAIRDND
HIYGVIAGYGVNNDGHEKAGFTAPNADGQAACVKQSLKMAAIQASDVEYLEAHGTATRVG
DEVELEGIKDALGVTEINARDCFIGSVKSNIGHTNTASGVASFIKTLLALKHQKIPPSCH
GTENKHTSLENTRFRLTDVAADWVSHGGVRTAGVSSFGIGGTNVHITVQSIEEQPASSQC
QAELITLSSKSCEGLVKTMAKLGDFLDEEQHSYSLSDIAYTLQVGRGDYDYRTSLVVENV
EALKEALHSLKDSSKFPEALPDQTSGIVFMFPGQGSQYVNMAKDLYQELEIFKTLLDECH
ERLSRQFSIDLIGLLYSGDSEKDSEKLQNTQITQPVIFAISYSLAKTLELLGIEAKAMIG
HSIGEYVAATMAGVMTLDEALKLVAIRGTIMQECEPGVMLSVAAGRDDLEPFLTDKVALA
TVNSPNSCVIAGSQADIEKVQQRLVDKNFRTRLLKTSHAFHTPMMKPGAEKFKAALAEVN
WQKPTKAYISNVTGQWITPSQANSVDYWVEHLCQAVEFHAGIMTCLEKPGLNVFLEVGPG
RTLSTFVKQIAASDANISTLNMMRHPLEAENDRNYLLKLVGQLWMRGISVNWPLLYQNTH
PKRISLPGYQFAGENMVMGASILATKGVEKASETKIQKNEISEWLYTEAWEDISLPDEAT
QSDIRVALCFVPDITWCQPLCNSLKLEEKSIKFVLPADAYTSAENVITLVPGDKRHFGKL
IDELKQDALLPDSIIFAWPLSGQSDLETSWFSVITLIQSWTTSGSMTDFRLLLANTKQPE
HTMLNGLVKVITQEVSKCHPRLVQISPLESIARQCEILTEELLATDERFIVNRTQTGRST
LAYHKLKAGLLKENTLLKNEGVYLITGGLGDLGLLFAEYLIKEYGAKVILSGRRALPGKH
EWKHLVSLDHPEAEILQRLDELSELGKGEVAYYSSNVSDKHEMQALLDAIEEQYGCLHGI
ICAAGVTRGNSFQGINKLTLEDCTPQIETKVEAYQILAELTENKPLDFCLLCSSIASVLG
GLSFSAYSSVSSFADAFAKQQNSQGKPWISVNWDGWVFERNNSGDPIGSSLDQLLIEPDE
GLKILECALQSPLRGQLIISTGDLNKRFEQWVGGHLKPFKLNEFNHSQRAVVSKAQIVGT
IVSVWQDFLKVTNISRDDNFFELGANSLDMVQVNKRLTDALDMDFSVVDMFSYPTSELLA
DFIVNQYGITHDTGEQAEHSDTLNQHRDPSAQLNQSSTPIDRQIAIVGLAGTFPGAENIH
EFWENLTFGKESVTTFSKEELSEEGIDSGLLENPNYIRAKGVFPNAGEFDAEFFGYTPYE
ARQMDPQVRALHTCCWQALQDARIATKDNRAKIGLYASASGNLQWLAQAMATAEGSAGQY
SAMTVADKDYMSTIVSYKLNLTGPSMVLSTACSSSLVAVNEAVKSLRAGECDIALAGGVS
ITLPIKAGYVFEEGMIHSKDGKCRAFDIQASGTVFGDGVGIVVLKPLKQALADNDNIYAT
IIGTAINNDGGMKVGYTAPSTKGQVEVIQSALRDANAMAESIHFVEAHGTGTTLGDPIEF
NALKQAFSTDKKNYCRIGSVKSNIGHLNSAAGIAGLIKATLAVKNRILPPTLHYARPNKE
IDVANSPFIVNNQYTELNDTRNPIRAGVSSFGIGGTNVHIVLEEAQVNKDKSFNKKVDNR
LPIVLSAPDDKSLQCYKQQLKTFVENNQHQMSVSDIAYSLMQREPMASQFVASACDYDAL
IKALSSSEKDNVKVKLGTTKRKVVFLFPGQGAQYVTMGHELYHSNGLFKEWCDKGFTLAD
KYCSIDLKSLFHSRDEDRNLYNTEFAQPLLFIIEYALAQVLKSYGVTPDAMIGHSLGEYV
AAALAEVFSFEDAIKMICARGKLMQSTEDAVMLSVMSSSESVKEILTGSLEIALDNSSDL
CVVAGSDSDISSFESDCEAKSIKTKRLRVNKAFHTRYMEPVLGDYASIIREIAFNKPQIA
FISNVTGKWAEADKVVEYDYWVNHIRQPVRFRESITEVLKEGNCLFIEVGPGHGLSTLTE
NHSDYHANHICISCFDRKNEEINKHSELVQKLGKMALLKIDVNWHAEMADLQPRLVHLPP
TPLRGTKYPTDIKRLQALFSGNKNLGYQADKPEEQVSQSKVGSNPHPKAKRSVIDELSAI
WKLILGVDTIKEDDNFISIGGSSLSAVQVIAKAKSIDLPVNMSMLLSGQTLAQISASLQS
DDETTHKGWQFNEHFSPEMYPGSASCLYSAVREKLKHEHGLTSDDAIMQVVDGSPLLGIG
VQQFENDTKIVSKPVNYGTLSGWPSLQECYSFSYDKQFFEDYEAYRHYCESELALGHLVI
VTGSDYYLPFSPSYGLPESEYIKRPLFENIELGDDDIIPHAFVLVGKTPSGYQIYDGSFQ
YFGEITEQEFEKTVIGFKGLDFMQSHEVYNKSRSFMVITVTCDGKFHKDNDLKEQTLNRL
VTDFQTKQAIEGNESHLSYYIGLTALDKLIENPGLIASSSNFDLEEIFSRWYQQMLLLRK
FLKISKPEVSTECDHAFSIISEELEKVVACCKNSSDDKTIIDSLLLVKSNLSDIIKNLS
>A0A498QBC9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium innocens|TrEMBL
MARPDLAQLGAAALDLPCADRSPRPEARQTTMSDHQPSTVVDPDPIVIVGMAIEAPGGVD
TAERYWEFLSQRREGLCPLPTDRGWPIRDLLTGSCRKGFKRIRDCGGFLTGAATFDPAFF
GISLREAIAMDPQQRVALRVAWRALEGSGINPDDLAGHDVGCYVGAYLTGYGPDMAEFSG
HSGRLLTGTASGVISGRISYLLGLAGPALTIDSSCSSALAALHVAVQALRAGDCDMALAG
GVTVMGSPGFFVEFSKQHALSDDGHCRPYSAQASGTVWAEGAAMFVLQRKSAALRNGRRI
VAEVRASALNQDGRSAGLAAPSSAAQSRLFLRAMAQAGLGPEQIGMIEGHGTGTRLGDRT
ELQALAETYGDTEPGRGALLGSVKSNFGHAQAAGGALGLAKVLVSAEHGAVPPTLHAAEA
SREIDWDSHGLRLAQELTPWPAVDGQRIGAVSAFGISGTNAHLIVSMASIAGAA
>A0A7D3VNI9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinomadura verrucosospora|TrEMBL
MNPAPWFLPLREPPDGAPRLYVFPHAGAGSTAAQPLADLLTPRLDVRGLNLPGRQSRLDE
PPVTALEPLVSHLARELAVAAEPYAVFGYCGGALLAFLTVRRVHELGGRLPVRLFVGSFA
APDIALLPRRLPTLPSDLFWDEVLDLGGVSPEVAEHAELRPVFEGALRADYRLVGGYVHR
PAPPPPVPITVLHGGRDATLSRGELAGWRRQSTAATRVRTLDASHWLVEDAPEELAELLA
DELDGTGSKVPAGEHGERRRPPPDPTPRQGSGHERPGRDRTAGMGGA
>A0A447GAP5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium basiliense|TrEMBL
MLAAKADTAWHLHQLTTNHNLAAFIMFSSIAATLGSPGQANYAAANAALDAIAHHHPNAT
SLAWGYWETPSAMTAHLNHIDQTRAARNAITPLTTQHGLALFDAALTHHQPTLIPAPLNP
RTLNRLAHRNALPPILSALTTTRPHAATTTSPTTLSTQLATQTPDQQRHTLTTLVTTTTA
TVLAHPDPTTLDPDRPFKDLGIDSLTALELRNTLAQHTGQTLPPTLIFDHPTPTTLAHHL
TTLLTHHNNTTTPTGPHRPTATTNTDEPIAVVGMACRFPGGVDSAAALWELVSSGTDVMG
PFPNDRGWDLTQLFDSDPDAVGKTYARYGGFLAQAGHFDAEFFGISAREAQAIDPQQRLL
LEVCWEALETAGIDPATLAGSQTGVFAGTWAQSYGDGNSHSAEGYAMTGSATSVASGRVA
YLLGLQGPAITVDTACSSSLVATHLACQSLRNAESSLALAGGVTIMTTPGPFTEFARQRA
LAPDGRCKAFAAAADGTGWGEGAAVLVLERLSDAHRHHHRVLAVIAGSAINQDGASNGLT
APNGLAQQRVITQAAANAAIDLDHVDVVEAHGTGTTLGDPIEATALIATYGSAPHRTHPL
WLGSIKSNLGHTQAAAGAAGLIKMICALNHDTLPPTLHVDHPSPHVDWSAGTVQLLTQPT
PWPDTDHPRTAAVSSFGISGTNAHVILQTPTTPAPTTPTPTTTPACDPPPRIWPLSARTP
TALHAQAARLHHHLLDHPNLDLTDLAHSLATTRTHHPYRAALTTPTTSNNPREDLLEALH
ALTTNHPHPGLASHHLTHTKKIVFVLPGQGAQYPAMAAQLYEHHRIFAETLNECDHALHP
WTGWSVRDVLTQHPSAPPLHRVDVIQPVLFAIMISLAELLRTYGIIPDAVIGHSQGEIAA
AHIAGALPLDQAAKIVALRSQALTALSGHGAMASVRLSPHELHPHLQPWNNTLTIAAANG
PTHTIISGDPTALEQFTATCQHHGIHIRPIAVDYASHSPQVEQLHQHLLHQLGELTPQPA
QIPLYTTVQSAQTDDPLDTTTMNADYWYRNLREPVEFHNTITTLLAQGPHTFIELSPHPV
LAPALTDTITTTDQTQSTVITTLHRDRPHLDTLTTALAQLHTHGHSPHWPTLYPHAHTLE
LPTYPFQHHHYWLTPTTTTDITAAGLDHPDHPLLGAITDLADQDQIILSARLSTHTQPWL
ASHRVHDTIIFPAAGLIELLLHAGQHTHYPTIDELILHSPLTLPEHTPTDLQITIHPPDD
TNRRPLTVHTRTTTNDHHNPWHLHATATLSTHQPPTPTNHTPPPLQPINPDDFYHQLATH
GLHYQPPFQNVHALHHPPTNPDTIYAHIALPPDTTTTGYGIHPALLDAALHPLTTLTHTH
PDTDPDTTPLPFALTGITLHATTATQLHTQLTRTNTNTYTLHATDPTGAPVITITTLTLR
DLPHTPQQPTPTPHHSLFHLDWPALPPTTPNTPETPNTNWALITPDTTNNPHLPPTLNHL
PTHPDLTHPDLTHHDLLIWPLPQPHPNTTDLQHLHTLTQHTLTQLQHWLTRPDTTHTHLA
ILTHHAITTSPHDPHPNLAHAATWALIHTTQNEHPHRITLIDTDHTPTTNTTLPTLLTTL
KHTTEPQLALRHGTTHTPRLTPTPQTTPAPETTPTWDPQGTVLITGGTGMLGALFAEHLI
THYGTRHLLLVSRRGPTAPGATELHQHLTNLGAHVTITACDTTNPHHLATLLDTIPTEHP
LTAIIHTAGILDDAVLTELTDTQLHSVLAAKADTAWHLHQLTTNHNLAAFIMFSSIAATL
GSPGQANYAAANAALDAIAHHHPNATSLAWGYWETPSAMTAHLNHIDQTRAARNAITPLT
TQHGLALFDAALTHHQPTLIPAPLNPRTLNRLAHRNALPPILSALTTTRPHAATTTSPTT
LSTQLATQTPDQQRHTLTTLVTTTTATVLAHPDPTTLDPDRPFKDLGIDSLTALELRNTL
AQHTGQTLPPTLIFDHPTPTTLAHHLTTLLTHHNNTTTPTGPHRPTATTNTDEPIAVVGM
ACRFPGGVDSAAALWELVSSGTDVMGPFPNDRGWDLTQLFDSDPDAVGKTYARYGGFLAQ
AGHFDAEFFGISAREAQAIDPQQRLLLEVCWEALETAGIDPATLAGSQTGVFAGTWAQSY
GDGNSHSAEGYAMTGSATSVASGRVAYLLGLQGPAITVDTACSSSLVATHLACQSLRNAE
SSLALAGGVTIMTTPGPFTEFARQRALAPDGRCKAFAAAADGTGWGEGAAVLVLERLSDA
HRHHHRVLAVIAGSAINQDGASNGLTAPNGLAQQRVITQAAANAAIDLDHVDVVEAHGTG
TTLGDPIEATALIATYGSAPHRTHPLWLGSIKSNLGHTQAAAGAAGLIKMICALNHDTLP
PTLHVDHPSPHVDWSAGTVQLLTQPTPWPDTDHPRTAAVSSFGISGTNAHVILQTPTTPA
PTTPTPTTTPACDPPPRIWPLSARTPTALHAQAARLHHHLLDHPNLDLTDLAHSLATTRT
HHPYRAALTTPTTSNNPREDLLEALHALTTNHPHPGLASHHLTHTKKIVFVLPGQGAQYP
AMAAQLYEHHRIFAETLDHICAAFDPHLDTPLHDVLTAPADTHPAQLLGQTAYAQPALFA
YGAAMHAVLTHAGITPDYLLGHSLGELTAAYLAEVLSLPQAATLVAARGRLMQTCTPGAM
LAIHTNPEHLTDQLHHYPHTTIAAINSPTSIVIAGPHDDINALHQWCTTEHYQTTQLPVS
HAFHSPTMDPALPEFHAIATTLTWHPPTVPILSNLTGQLATPDQLTSAHYWTQHLRQPVR
FADNLTTLLAQGPHTFLELSPHPVLAPAITDTLTHHTNTASTVITTTHRDRPHLDTLTTA
LAQLHTHGHSPHWPTLYPHAHTLELPTYPFQHHHYWLTPTTTTDITAAGLDHPDHPLLGA
ITDLADQDQIILSARLSTHTQPWLASHRVHDTIIFPAAGLIELLLHAGQHTHYPTIDELI
LHSPLTLPEHTPTDLQITIHPPDDTNRRPLTVHTRTTTNDHHNPWHLHATATLSTHQPPT
PTNHTPPPLQPINPDDFYHQLATHGLHYQPPFQNVHALHHPPTNPDTIYAHIALPPDTTT
TGYGIHPALLDAALHPLTTLTHTHPDTDPDTTPLPFALTGITLHATTATQLHTQLTRTNT
NTYTLHATDPTGAPVITITTLTLRDLPHTPQQPTPTPHHSLFHLDWPALPPTTPNTPETP
NTNWALITPDTTNNPHLPPPSTTYPPTPTSPTPTSPTTTSSSGPSPNPTPTPPTSNTSTP
>A0A385ZFF5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces griseorubiginosus|TrEMBL
MAEVTVTDSTTGTCGDEPIAVTGSMTDTDGPEPIAVTGSMTETDGPEPIAVIGIACRLPG
APDPSAFWQLLREGTDAIGVPAADRHPAQDGNERPGGWLDRVDGFDAAFFGVSPREALAM
DPQQRLALELGWEALEDAGIAPDSVGGTPAGVYVGAISDDYATLLRRGGPQGITRHMFTG
TQRGVIANRLSYSLGLRGPSMTVDCGQSSSLVAVHLAAESLRRGESNLVLAGGVHLNLVP
ESTVAVERFGGLSPDARCFTFDARANGFVRGEGGALVVLKPLTRALADGDRVYCVIHGSA
VNHDGAGESLAVPNAEAQHEVIDAALAAAGIRPDAVQYVELHGTGTPVGDPIEAAALGAA
FGTGPDRPVPLAVGSAKTNVGHLEGAAGVVGLVKTALSLHHRELPASLNFETPNPAIPLD
DLNLRVQTASGPWPQDDRPLLAGVSAFGVGGTNAHLVLGEAPTPTLTTDTATAQTSGPVP
LVVSAGSTAALAAYGKRLAERLEADAELHLADMAHALVTTRALLPHRAVVVAGDRDSAID
GLQALAKGTPHPQVIAGAGPAPATGRGPVFVFPGQGSQWAGMGADLYADSPVFRDALDAC
AAALDPLTGWSLIDTLTGDDDTWLNHVEMVQPALFAVMTSLARLWIAHGIQPAAVIGHSQ
GEIAAAHIAGILTLQDAARIVTVRSAAMRQLAGHGVMATVSKDAPWVLQHADDRVTIAAH
NSPTTTVISTTPDTLDHLTTQWASQGVRVRRINVDYASHSPQVDAHQHHITTALADIQPH
QAIIPMVSTVTGQPVEGTELTADYWYTNLRHPVRFHQALTHLIDTGHHTTIETSPHPVLT
PAIDETAEATGTAVNALHTLRRNTSTPFATVLAHAHTTGTTPNWTALLPTPQHHTPLPTY
PFQRRSYWPEFIEAASPTALITESEEQEEDGTSFAPTPQLSELLNVVLNECARVLGHSSA
SEVPEHLPFKELGFDSFAGVELCKRLSALLGHRVPVNATYNHPSPADLAAFLQDELAGVS
GEGAPVTGADQTPVDDDPIVIVGMACRFPGGVRTPDDLWRLLLEERDAITEFPEDRGWNI
EELYNPDPTHPGTSYVRRGGFLDDIAGFDASLFGIAPREALAMDPHQRLLLETSWEAFER
AGIDPGSLRGSRTGVFVGTNEQDYATYTAPQQAQGSEGFLLTGHAASVASGRIAYVLGLE
GPALTVDTACSSSLVALHLATQSLRNGECDLAVAGGASVMSTPGMFLEFSRQGGLSPDGR
CKAFDESADGTGWSEGVGTLLIERLSDARRNGHPVLAVVRGSAINQDGASNGLTAPNGRS
QARLIRTALANAGLTPTDVDSVEAHGTGTRLGDPIEAQALLTTYGQQRATEAPLWLGSIK
SNIGHTQAAAGIAGVIKTVLALQHGVLPRTLHLTEATSHVNWSSGAVRLLAEARNWPDTD
RVRRAAVSAFGISGTNAHVILEQAHVPVQAEESVPSGRPVPLVISAGSPDALAAAGGRLA
QWLDDRTELHLPHVAHALVTSRALLPHRAVVVAEDRDSAIDGLQALAKDRPAPHVITSTG
PVTPARRGPVFVFPGQGSQWAGMGADLYATSPVFRDALDACAAALDPLTGWSLIDTLTGD
DDTWLNHVEMVQPALFAVMTSLARLWIAHDIQPAAVIGHSQGEIAAAHIAGILTLQDAAR
IVTVRSAAMRQLAGHGVMATVSKDATWVLQHADDRVTIAAHNSPTTTVISTTPDTLDHLT
TQWASQGVRVRRINVDYASHSPQVDAHQHHITTELAHIQPSAATIPMISTVTGQPVEGPE
LDADYWYTNLRHPVRFHQALTHLINEGHHTTIETSPHPVLTPAIEETSEATGTPLTALHT
LRRNTTASFTTALAHAHTTGTTPNWTALLPTPHHHTPLPTYPFQHEHYWLDRPQLAAAVQ
PGVDVAGHPLLSAAVRLADGGVVLTGGLGPAAPEWVADHAVMGSVLLPGTAFVELAVRAG
DEVGCGTLEELTLRAPLALLAPVAVQVVVEEPDDSGRRRVTVHSRPASASSPVDDSWTLH
AEGLLAIGDGQPSTDDADFAVWPPAGAQPVSVAGLYGGLAAQGYDYGPAFRGVRALWRRS
DDEVFAEVRLPDELGADAQEFVLHPALLDATLHAVAGAGLLPASDGIRLPFAWSGVRVHA
AGASTLRVRLRRTGPDAVSLTAADESGATVVSVGALALLPIAPEQLRAASRDARLDALLA
LRWEEVAAPGGPSGLSVPEHWAAVMSRSEEIDEVCGAVPPEEPSAVLFDASARPGSPYEP
KDAVQGALRVVQRFVTDPALRNCVLVVRTRGAVAALAEDRITAPADAAVWGVVRSAQSEH
PGRFVLVDGVAGAEAPVAPGLVLATGESQLALRNGSFFAPRLDRHRPEGGSPTVFDADRT
VLITGGTGALGGLVARHLVDSYGVRRLLLLSRSGPGAAEVAELVADLTGAGAVVDVRACD
VGDRAALAGVIAEVQESGHPLGAVVHAAGVLADGTVAGLTEQAVDAVLRPKAEAALHLHE
LTADLDLSAFVLFSSVAGVLGNAGQANYAAANAYLDALAEVRAGLGLPALSLAWGLWEQP
SGMTAELSGQDLARMRRSGLLPLSAEEGLALLDAALAGSPGAAVLVPARVDVGALVRAGR
AVPALLSRLAPRVGRRTVARAVEAGSGALSAFEERLAGLSRDERERLLLSVVRDETALVL
GHAQGAVLDVAGEFRELGVDSLMAVEVRNRLAAVTGLTLPSTVVFDHPTPQALARLLHER
LTGALPEAGQVVVERPADDDPIAVVGMACRYPGGVEGPLDLWQLVLDERDAVGEFPADRG
WDVDALFAAGSGAGGTSATRHGGFLDDAAGFDPSLFGISPREALAMDPQQRLLLEVSWEA
LENAGIPADAVRGSRTGVFAGLMYHDYGTGLTQVPEGVEGYLLTGGAGSVASGRIAYALG
LEGPALTVDTACSSSLVALHLAVQSLRRGESDLALAGGVTVMVTPDTFTEFSRQGGLSGD
GRCKSFAEGADGTGWSEGVGMLLVERLSDARRNGHRVLAVVRGTAVNQDGASNGLTAPNG
QAQQRVIRQALADAGLSPDDVDAVEGHGTGTVLGDPIEAQALLATYGQGRPADRPLWLGS
VKSNIGHTQAAAGVAGLIKMIMAMRSGVLPRSLHSATPSSHVDWASGGVELLSGAREWPD
GDRVRRVGVSSFGISGTNAHIVLEQAPAGDEPSERGPAPAVVPLLLSAAGDEALRAQATR
LAGVLEQAGDSAAALVDVGWSLAEGRAALPRRAAVIAPGPEEAIERLRALAEGRASAGVL
TGRAEPDGRLAVVFSGQGSQRLDMGRELHAAQPVFAAAFDEICDHFAPHLPLPLREVVFG
ESAELLNRTGYAQAALFAVEVALYRLVEHWGLRPGLLIGHSIGEFAAAYVAGVWTLPDAC
ALVAARGTLMQGVTADGAMAALAVTPEEVGPVLAPYGDRVGAAAVNGPASVVVSGDRDAV
EEVTARFEAAGRRVQRLRVSHAFHSAHMDTMLDAFAEVLAGVPFRPPTLPVVSNVTGSLA
DPEELCSPAYWVRHARDAVRFADGVTTLHGESVTAYLELGPAGVLTGAVRDSLPEEAQPV
IVSALRRDRSEVATFTEAMAGLHLSGLSVDWSAAFARTGARMVDLPTYPFQHSRFWLQAP
ERSTRPALERLAGLQPDELARTLNVDEIHARAVVPALADWLRAQEQPQRRELSDRQVTWV
PAKTLRGSQRLDGRWQVVVPAGAHPLDTRVVALAGALERAGAEVVMGDVTVVEAELTGVV
AVAALADDPGLFAVEVARQATGGAGLWFVTHGAVATGSGDPVLDPRQAAVWGLGQAMSLE
LPERWGGLVDLGGFDGDMDVLGAVLSGASDEDQVAVRNGRVLGRRVVALPTSRGGDRPWR
PTGTVLVTGGTGALGARVAEWLVDGGAEHVVLTSRRGEQAPGASELADGLRERGAWVSVE
ACDAGDRSALSEVLGRHRPRAVFHAAGVFEAGGIADLSADSWAAVLSAKADGALHLDELS
RELDLDLDAFVLFSSIAGVWGGIGQGAYAAANAVLDALAQRRRADGLAGTSVAWGPWAGE
GMAADGEIGAGLRRSGLVPMQPRDALAALQDVLDQDETCRIVVDADWERLLAAFEAARPG
PLFALLPHGTRPEVDTEAEEAGAAYARHIRALPPSEQDRTVSTLVRDMVAAALGHASSDA
LDMTQTFKTLGLDSMTAVEVRNRLTAATGLTLPTTVVFDRPTPRDLAKEVRDRLVGTASS
TAPVPTDRPTVDEPVAIIGMACRYPGGANTPEDLWRLVAEERDAVCDFPEDRGWDLATLY
DPDPAATGTSYSREGGFLDDIAGFDAGLFGISPREALAMDPHQRLLLETSWEAFERAGIP
PTSLRGSSTGVFIGAGEQDYAGGVTDAPEGVAHHLLLGHTASVLSGRLAYVFGLEGPTLT
LDTACSAGLVALHLAVRALRSGECDLAVAGGATVMSTPGGFVEFSRQRVLGRTGRCRSYS
DDADGSAFSEGIGTLVVERLSDARRNGHRVLAVIRGSAINQDGASNGLSAPNGQSQQRVI
RQALADAGLAPGDVDAVEGHGTGTPLGDPIEAEALLATYGQDRPAERPLWLGSVKSNIGH
TQAAAGIAGVIKMVQALRHGVLPRTLHLDSPSSHVNWASGGVELLDRAREWPSVERSRRA
AVSAFGISGTNAHVILEQPEPETSEPSTADVVGPVVLPLSAHSGAGLRGQAQRLRELLDA
APELELSALGRALAAHRVTDLEHRAAVVAEDRETVLAALGALAEDGTHPQLTTGSGAPGA
DPVLVFPGQGSQWPGMALQLLDSSPRFRDALAECDAALGEFVDWSVLDVLHERPGAPSMG
QLDVVQPLLFAVMVALARTWQAAGITPAAVVGHSQGEVAAACVAGALSLSDAARIICLRS
RTMQEKLSGLGAMASVAQPQAWVAERLERWGGCLSVAAVNGPTSVVVSGEAAAVDEFLAD
AEEAGVRARRVKGAIAAGHSAQVELVEDRVRAELAPVSPRTGEVPIVSTVTGEACDGSGM
DADYWYRNMREPVRFDAAVRELLTRGHRVFIEVSPHPVLLTGLQETVEDAGTSASVLGTL
RRDEGGADRFNASLAAAYVAGVDVPWRETLYARTPDTFVDLPTYAFQHRRYWLDAPRQSA
YFATPASGTTQPEAPADEAQRRFWAAVESGDLDTLAGELPLVNGQLASLREVLPALADWR
TRSREDAAVDRWRHRVVWERIGTPARPALSGRWLVLVPDDAGARAVADPVESALRAHGAE
VTRVGFAADAERGELAETLLALRASDAERELVALGASSGEPEPVGLRVGNAEPEPVGVLA
LTGLLSGAHAEYEAVPRGLAATLSVVQALMDTDLAGDAPLWVLTRGAVAADPGDLVQAPE
HAMVWGLGATMRQEHPERWGGVVDLPDGADDPLDPRVLTRLVGIVSGATDEDEVAVRTSG
ALTRRLVPAPGDTAATGLDLAAQQSDEGTEAGEWKPTGTVLITGGTGALGGQVARHLAEL
GAPHLLLVGRRGPDAPGAAELAAHISESGTKVTVVACDLGDRHALAQLLAEIPPEYPLTA
VVHTAAAVDDALLSSLTVPQLDRALRVKALAARNLDELTRDLPLELFVLFSSFAGVTADA
GQGGYAPGNAFLDALALHRRALGLPALSVGWGHWAGGSGLEGGEVIANRLHRFAMESMAP
ERAVRALDRALRLDGGRGHVVVADIDFARLAPGSIGARPTRLFLEQPGYRDALETAAARD
ASDGAGPAGGDDTVARWRTEAVAATGAERVALVRDLVLRHLASVLGHANPEDLSATRLFR
DLGIDSLTAVEFRNRLGAATGLRLPVGVVFDHPTPEALAAFVGAELATEAPDPTGPAPSP
ADEAGSVEEVLDRLEAALDRVDRVDRGGLPTSATVANRLRDLLARLPQESPAGPAPSTDA
GGLEAATTAEEVLDFIQERFGT
>A0A0H5NS80|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia farcinica|TrEMBL
MQDDVTAVDPIAVVGMACRFPGNIDSPESLWRFVIDGKHTSSKFPADRSMTELADIAAPE
VVAAMAPMGGFIDEPGEFDPEFFGISPREAKAMDPQQRIVLELTWQALEDARIDPNALHG
SDTGVYVGAMSGDYAYLIPGQKDLDPGYVATGVSQSVLSGRISYVLGLQGPTMSIDTACS
SSLVAMHLAARALKAGECSLALAAGVSIMSTLTGFYALGQHGAISKEGRSKPYSADADGF
CMSEGAAVLVLERLSDARRHGHQVFALLRGAAVNQDGATKGLTVPSAQAQRKVIEAALAD
AGLGPGDVDVVEGHGTGTPVGDPVELEALFATYGSARPAGSPVRLGSVKGNFGHTQAAAG
LAGVIKMIEAMRHETVPPSLGVSEPTGAVDWSSGAVRVVTEASPWPAGARPRRAGVSSFG
ISGTNAHVIVEEPPRTSPAPSEPPRVAPPVLLWPVSAKTPAALAAQAAALAEHVTAHPGY
ADQDIAYSLTATRATFDHRAVAVGGNRAELLDALAAIAAGRPVGPIRGQAMPDRGVVFVF
PGQGGQYRGMAKQLIAESPEFAAGIRECDAAFAEFVDFSVFDVLTEAAGAPTLDHIDVLQ
PALFSTMVSLARLWRALGVAPAAVIGHSQGEVAAAYVAGALSLADAARVVALRSRALRTL
AGTGTMASISTSAARVRELLVEVPELDVAAVNSPTTTVVAGAPEAVERMLAVCEREGLRA
RRIHVEVASHTGAMETVAEEIRAALAPITPRPSAIEFFSTVTGDVLETENLGADYWFANL
RQTVNFEDGFQAAFQSGYNAFLEMSATPVLTAAMHESLDQFGAFADSCLIVGTLEREDAG
LRRFLTSVATAHVHGVSPRWSRLYDPATHTAVPLPTYPFQRQTYWLASVHNANGGKPSGL
GLADPGHPLLGAMTELPGADRFQFSTRLAVATHGWLCDHALHGNVLVPGAMLLELALHAG
DQVGCPGVEKLTMYTPVTLPEQGAVHLHLVVGEAKAPGRRSIAIYSRPENEDAPAGQNLW
SLHADGTLTTRSYAEDADQHGVELWPPVGAQQALEPERAYQTLAALGYHYGPIFQGMRAV
WRRGEDIFAEVALPESVADADKYGLHPALLDAAMQSVAAVASMMPTEPGAIRLPFAWERV
QLHAIGAKALRAKLTPAGPDRVRWVLADHNGRPVAVGTLQVRSISMGALAQRGLSGRQDS
LFGVDWPALPVQRTRWTARPGEWAVLGDLPPGLTAGAELTVYPDRAALSAALADGAPVPK
VVLATRTAAGRHIDAGPTEAVRAELAATLAWLQDWLADERVTETRLVLMSTGVQAVEPAE
TVTDLSGATVWGLVRSAQSEYQDRILQLDLDGAGVTLDQLATAVALDEPELALRRGTFHG
RRIRSGLDAAATAGARLAGHWRLDIPGTGNLDDVTLVAGTAPAAELAPGTVRVALRAAGL
SFPVALTGLAAVAGAPRRLVHEAAGVVRAVAADVTGFAPGDAVFGLVDAIADTVDADAAL
LAPVPAGWSMPQAAAAPVAYVTALHALREAAATTGERVLVHCASGGVGTAAVHLATHLGL
EVFATASERKRDTLRGMGVAEDHLADSRSAEFATRFAGRGIDIVLDLLPAELTDASLGLL
GATGRFVDLARGAVRDPRAVREACGVTYRTFELGDLDRDTLAGLLAEIARLAAAGTVPAL
PSTRFDIRQADAALRHLGEARHVGKIVLTWPPAFDPDRTVLVTGGTGTIGAIVARHLVHA
YGARHLLLTSRSGPAAEGIDDLVAELTDAGARVRVAACDAADRAALAAVLDTVPAAHPLG
GVVHLAAALADATFAQLTPDHLGAVLGAKADGAWHLHELTRDLDLSMFVLFSSAAGTFGA
PGQANYAAANVFLDALARRRYHDGLAATSMAWGWWAEDTSNTGALDDKDRARLTRMGVTP
IETEQALALFDAALHTGRPYLVPVGMDLSLLRVASSVAELPPFFRALLHSRPRATQQMGD
SSQLAKRLAGLSPAEQHAVVVDMLETPIAMVLGYSSPEAVHPDREFTEMGIDSLSSIELG
THLRAITGVKLANSVIFQYPTVNLLAGHVLDQVTPQDAELADPIVSEVEMLLDRLAALHD
DGQVPEPLLERLTGSIGRLRGGEVAVGDGARP
>D7E4V4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc azollae (strain 0708)|TrEMBL
MSADSINTALAELESLVNSCEKDLIRFIGEKKMKSENQMSTHKINRQLQQNPIAIVGMAS
LLPQARSLRQYWANIVNKIDCIIDIPESHWSVKDYYDPNPRTPEDKTYCKRGGFIPEVDF
NPMEFGIPPSTLEVTDVSQLLSLVVAKEAMEDAGYGEAREFSRDYVGVILGVAQAKQLGI
PLSARLEYPIWEKVLKSSGLSDEDTQKIVGKIKSAYIKWDENAFPGMLANVVAGRIANRL
NFGGTNCVVDAACASSFGALKMAISELVEHRSDMMLTGGVDTDNSIMAYISFSKTPAVTP
SDNVKPFDAKSDGMMLGEGIGMIVLKRLEDAERDGDKIYAVIKGIGTSSDGRYKSIYAPR
KEGQVKALERAYNDAGFSPATVGLMEAHGTGTMAGDPTEFGSLRDFFTQYDNKKQHIALG
SVKSQIGHTKAAAGAASLIKTALALHHKILPPTINITEPNPRLDIQNSPFYLNTETRPWI
RAEGQAPRRAGVSSFGFGGTNYHVVLEEYEAEQQQAYRLHNAPSEVLLFGSTPAELITKL
EATFNNLQSNEGERHYSQLVQESKSVAIPQAAARIGFVAENLQETCKLLKVSIDLLKNKQ
SAVSWEHPQGIYYRASGMELVGKIVALFSGQGSQYLEMGREAVMNFPPLRRLYSQMDGLL
IKDNLQPISEIVFPHPTFEEPEKNAQIAALQRTEYAQPAIGVFSAGLYSIFQQAGFKSDF
AAGHSFGELTALWAAGVLTEEDYLFLVKSRGQAMAAPKDPDHDAGSMLAVKEDINKVEAV
LRNFPQVAIANFNSPTQVVLAGPTGEIKKIQQKFQELGYGAVLLPVSAAFHTPLIAFAQK
SFAIATKSVAFQNPKVPVFSNVTGKEYPQELSGIQRVLEGHLSSSVLFKQEIENIYAAGG
YCFVEFGPKGILANLVKDTLGDRPHLTVSLNPSTQKNSDRSLREAAVQLRVIGMALSNLD
PYQLPPVISATPTKKALNVKLKGVNYISEKTRSAFTEALQDGYKIKGVQESGNLEVKNSV
IPTTRVTPSTNGHNGNGHKKTPVITSPQQPQMNPANFSNQVTKELLPTARYAIAERLGGK
METSDQNNNFQQVLESLENLLNQFQHNQGDNLQIHSIYLNHQMEYAKTFFQLMQQQNTLF
INRNSSETAYIKQVVMESFERSMMQFHNQQAETLRIHEQYLREQVEYTKNFFQLIQQEYS
LLIDGTEITQPVIPPQFTETHTNSLRELMPPNPEPTITETVVPPTDKIVETQPVIEPVIQ
TIAPVIEALPLSKIAEPLIEIPTRVVEKQPEPVAPVALIPEPTTSGVNIRELGKNLLNIT
SEKTGYPIEMLEFDMDMEADLGIDSIKRVEILGGLQELYPDLPKPNLEELAEKRTIGQVV
EYIQKQVIGESVQVTEKKAEEGAEQLPLRSSQSLVPSPQPPEDSNKYADLAQTLLNITSE
KTGYPVEMLELDMDMEADLGIDSIKRVEILGGMQEAYPNLPKPNIEELGDLQTIGQIVNY
LQKLVGGEKKKLDFDQITADSHVPEVVNLTPPPVVDPNLPRRPVKLKTLPRPDFWECKPP
EGHIGLITDDGSLTTTKLTHALIKQGWKVVVLSFPQSLIPEQLRLPADVTRITLANMSEE
HLQLLLQSITAKHGKIGAFIHLHPQFTTSYPEAEKAIVKQVFLMAKHLKQSLNTAANLEG
RVSFCTVARLDGAFGLDYTENFGVIGAGLFGLTKSLRWEWPQVFLRAIDLSPTLDPHQSA
EYIVAELHDSNRYISEVGYNSKGRVTLIAAAE
>A0A0D5M5S0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Halomonas sp. KO116|TrEMBL
MTKRVAIIGAAHRFPGTTPETFWQDLQAEKYLVTEVAADRWSHEAYLHPDKRHPGTSVTF
AAGSLGDISGFDAEFFGISPREAANMDPQQRMLLELAWEAMEDASILPSSLRGSQCGVFL
GVASLDYSYRLADDMSAIDASTATGNTSSIASNRLSYVFDLHGPSMSLDTACSSSMVAFH
QACQSIRSGETNMALAGGISLHLHPYGFIIFSKASMLSPTGRCQVFDEAGDGYVRSEGAG
IFLLKDYDQAVADGDNIIAVVAGSAVNTDGHKSGLTVPNPSAQIDLMKRAYQQAGISPDE
IDYLEAHGTGTAVGDPIETRAIGEALGQHRKTPLLIGSVKSNLGHLETASGVAGLAKALY
SIQHREVPATIGIRKLNPRIKFDELNLSVVTKGQPLKKEGRLVIGINSFGFGGANAHVIL
ESPPERSKPEPQAPGSTLPIRLSARSAEALTQSAETLAHYLRENASHKSSEISLYDIAYT
LFHHRERHRHGALLFAQTADEAATLLSEFAGGENNDIATLERLPNAVGPVFVYDGNGCQW
ETMGRDLLSESPTFAAAIDHVDTLFQQHGDFSLRAELEGRNGQDDDNRFALTEIAQPALF
ALQVALTEWLREQGIAPIAVFGHSVGEVAAAWASGALSLEDAVKVIFYRSDYQGKTRGQG
EMTAVAMSADDIAEWLENPEYSKVCLAGINSPKGITLAGDSRQLSALEAALSGQDIFAKR
LPLDYAFHSPAMNSIKAGVINALADITPRTTQIPYYSTVTGELSDGLELDATYWWKNIRE
PVLFDAAASALMEQGHNVFVEIGAHPILRRYLNESLRQLERPGLVFGTIERHKPGFEGLQ
RCLGQLLLSGLDLASRHLPVVGQRVPLPRYAWQRSHHWVQGTNDGQGLLMRYYQHPLLGY
PLAQHEHTWESQLDTQRQPWLADHVVGEGAVFPGAGFVELTLAAALQLKDSPLLDIEELE
IRAPLLLDGPHGRAMRLTYLPEDGRLEIHSREPASGSEWQLNAVARTMRESRGFLLNRKA
PALPSRAPDYTLEEHLQMAERIGLHYGPAFQAISKGWIEGDAVIGEIALSDDVQAQLSTL
HVHPGILDSAFQMFIPLLAQHSEFAAQLAFVPVRVGRIQVNTQAGAPVIARAVMGKRAPH
SFTADFELYDAAGNAVAVLSKTRFKAIRLNRAHHQHFSYLDVELTPAPLRSEPLALPAEA
LARLADIATIYGKGTGHRYGNEVAPLLDSLSEAFAQQRPDAETDTDSEGAQHSPDVIWQL
LVQDYPDYFAPIHLVGRLGLHQQALRSGSSDLETLGISQEHLARLNRVLVGESGWQALAG
ELGELIDALITELPGGQRLQFLEAGPSAPALGERLLERSAQALYHDLTHYRVITTLDSTR
HQVEQLQERFPLMDMQHLDQNDTAALTAPTGVEKAQVAFVSVDITHPAATRQLIEALPAQ
LAPGAQVMLIGIAPSRWLDDLLATPGIDQTALEQATLIGWLNDQGFVVSTPMALEESENG
AYLLHAHYPLAADEDESTVTQRRHLVVADQNNEALAANLVEALQSQDASALLSISQSEPA
ELLAQALMQPALANHSEQTLNVIDLRGLGASSTEAQTARCDHALKWTLALEQQSLAASLW
LVTRGLSALWQASPATSANEAPGDAALWGFGRSLANEAVGHNVYLLDVPATISEPALNAW
ATLLAQPDSENEALIDHQGHRFATRLRTLPAPRPAAVAPTNERAQQPQQAMTLGFTMPGQ
LRQLTWRPRPLPPANADEVAISVKATGLNFRDVMYTLGLLSDEAIENGFAGPTLGLEFAG
VVESVGSNVTHVTPGQAVVGFGPASFSDKVIASQHAVAPLPEGISFAAAATIPTTFFTVY
YALKHLARLEPGEKVLIHGAAGGVGIAALQIAQWLGAEIYATVGSEEKRDFLRLMGIDRL
YDSRSLTFAEEILEDTQGEGVDVVLNSLAGEAINQNLRALRPFGRFLELGKRDFYENTHI
GLRPFRNNLSYFGIDSDQLMKVQPALTQRLFGEMMALFNDGTLSPLPFTSFSHTQVIDAF
RYMQQARQIGKVVVTYEQPIAPPQNDVLGTAAIQLSADASYLVTGGLGGFGLRTAQWLVE
KGARQLILLSRSGPASEEAQAAMAAFEQQGVKVVAAACDITDRAALTAVLKRAKTELAPL
RGIVHAATVIDDGLIRNLDAARIQKVLAPKIDGARHLDALTRETALDFFVLYSSATTLFG
NPGQANYVAANHWLEAFAANRRAAGLPATCVRWGAIEDVGFLARNTRTRDALQERLGGSA
LRSDDALNVLEQMLLTPGPSLGVLELEWGALARFLPTAEAPRFNEIARASDDVSSVDADD
DISALLANLSPEELHSTITDLLRAELASILLIDEEKLDIHRSVYDMGFDSLMGVELMTAI
ENRLGVQVSVMVLSEASTLDKLAGVLIQKMHQHDDVEEPPQNAIAALAAQHGTEGLNTAS
ASSLSATETL
>A0A100JUC3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces scabiei|TrEMBL
MPDEQKLLEYLRRATADLGQARQRLREEEDARHEPIAIVSMSCRYPGGADDPEQLWDLVS
SGTDAISEWPADRGWDTAALYDPDPDRPGTSYTRHGGFLHRAGEFDAAFFGMSPREALAT
DPQQRLLLETSWETLERAGIDPAVLKGTPTGVFVGAMTNGYGDGSRDQSDVQGLLHTGTA
GSVISGRISYTLGLEGPAVTVDTACSSSLVALHLAIRALRSGECSLALACGVTVMPHPDP
YVAFSRQRALAPDGRCKAFAAGADGTSWSEGVGVLLLERLSDARRHGRRVLAVVRGSAVN
QDGASNGLTAPNGPSQQRVIRAALADARLLPGDVDAVEAHGTGTRLGDPIEAQALLATYG
QDRDEPLWLGSLKSNIGHTSAAAGVGGVIKMVQALRHGVLPRTLHVDAPTPQVDWSAGAV
ELLTEERPWAFDPERPRRAAVSGFGVSGTNAHVILEEAPESAETPEAPETATPLPLVPWV
LSARGEDALTDRARQLLALADEDALIPGAVARALATGRSSLEHRAVVVAGDAEGFRTGLT
ALATGGEAANLVRGLAGPAGRTAFVFPGQGTQWIGMALELLDSSPVFAARMVACERALAP
HVDWSLTDVLSSATDLERVDVVQPALWAVMVSLAALWRSAGVEPDAVLGHSQGEIAAAVV
AGALSLEDGAKVVALRSQAITAIAGRGGMASVPLPPGELAGHLGPWGDRLSVAAANGPAA
TVLSGDTEAIDGIVAQLQAEDVRARRIPVDYASHSAHVEEIRERLLECLADIGPTAGRVP
FFSTVDLRWQDSGALDAEYWYRNLRQTVRFEEATRTLLAQGFRFFVESSAHPVLTVGISQ
TAEAEESDAVAVGTLRRDQGGLDRFLLSLAEAHTGGLAPDWDTLLAGHPGDTVDLPTYPF
QRRRYWLERPSAEAEDTAATDPADAAFWESVGGQDLPALTTTLGVRPEDPLTVVLPALAD
WRRRRDERATVDSWRYRVDWRPLPDAPAGRTADAPTGTWLVAVTDGTEGDPAREAVVRAL
REAGAVPVPVVLTEAHADRATLTAHLSEASTGPVSGVLSLVALDERPHPGHPHLPLGLAL
TLTLVQALGDADVSAPLWCATRGAVTTGRDDAVTGPGQHMVWGLGRCAALEHPQRWGGLV
DLPGTLDERAAARLCAVLAGLDDEDQVAVRPSGTYGRRLVRARPAEPAGSDAWQPRGTVL
VTGGTGGVGAHLARRLAEGGAEHLVLVGRRGADTPGAADLTAELTALGTRVTVAACDVAD
RDRLAELVAGLEQDGSRIRTVIHAAGTGLLVPLADTDPDEFADVLYAKVAGAENLDTVFD
RDDLDSFVLFSSISGVWGSGDHGAYASANAYLDALADRRRAQGRTATSVVWGIWDPEGGA
GMAANLVEEQLRGRGIPFMSPQVALTAFQQVLTDDETVVLVTAVDWDRFAPVFTSARPSP
LIGDLPEVRRALAEETAPAEAGDTTASTLRDRVAGLPPADRDRLLTDLVRGHAAGVLGHG
SADAIAPERAFRELGFDSLTAVEMRNRLNAATGLRLPLTVLFDYASASALARHLREELLG
PDTAAPAPLAAPAHVLADADDPIAIVAMSCRYPGDVRSPEDLWRLVADGRDVISGLPADR
GWDLDGLYDTDPDRPGTTYSAEGGFLYDAGQFDPAFFGISPREALAMDPQQRLLLETSWE
ALERAGIDPASLRGGQVGVFAGAAYQGYGGLSDVPEEVEGHLIAGISTSILSGRIAYTLG
LEGPAVTVDTACSSSLVAVHLAAQALRSGECSLAFAGGATVMGTPLSFTGFSRQRGLAAD
GRCKSFAADADGFGMAEGVGLLLLERLSDARRNGHPVLALVRGSAVNQDGASNGLTAPSG
LAQQRVIRSALAGAGVPSAEVDVVEAHGTGTRLGDPIEAEALLATYGQDRPADRPLLLGS
LKSNIGHSQAAAGVAGIIKMVQAMRHEVLPRTLHAEDPTPNVDWSTGAVELLTEPRPWTR
NGHPRRAGVSSFGLSGTNAHVIIEEPSEDAESGAPAGGSALGPAVPWLLSARTPEALREQ
AARLHTSLTDRPELPPAEVGRALATTRSAFEHRAVVVGTDRDTLLTGLAALAAGENDPAV
VRGTAATPGRTVFVFPGQGSQWVGMAVGLLDSAPVFAERIAECERALSPYLDWSLTDVLR
AAPDSPPLDRVDVVQPVLFSMMVSLAALWRSYGVEPSAVVGHSQGEIAAAVVAGALTLED
GARIVARRSRILTALVDRGTMLFVALPDEEVRERLAPWTGKLSVAAVNGPAAVTVSGDPE
ALDEFGERLSEDGVMRWTIPGVTFAGHSPQVDELRGELLDALAGVAPRRTDIAFYSTVTG
GVVDTTTLDTEYWYRNLREPVEFHRTVAALIEDGHDTFVETGPHPVLTVWIERSLEAADV
TGRVTGTLLTDDGGPDRFLTALAAPHVHGVPVDWSAVFAGAGARPVELPTYAFQRQRYWL
EPSATPAETAAGAPGADRPGDTAFWDAVERGDLTAVATALNLPDEDDSARTSLGGVLPAL
ADWQRGRRSRTAIDGWRYRVTYRTLHPTPGTPALTGTWWVVVPADAANHPVVTGALRALE
RHGALAVPVEIGAADTDRAALAARLGALTAPSGGVLSLLALAEQPYTDGTALPTGLALTT
TLLQALGDAGINAPLWSATCGAVSVGRSDALTAPAQATLWGLGAVAGVEYPERWAGLVDL
PADLDDRSGGRLAAVLAGLDGEDQVAIRPSGIYGRRLVRALPGDETAPVAWKPDGTVLIT
GGTGALGAHIARRLARSGTRHLLLTGRRGPDTPGAAELVAELADLGAEARVAACDAADRD
ALAALLAGIPDDRPLRAVVHAAGVLDDGVLDTLTPERAAGVLRPKMDAARNLDALTRDLD
LTAFVLFSSLAGTLGGTGQGSYAAANAYLDALAEHRRSLGLPATAVAWGLWAGDSAANSA
REQLVRNGIPPMDPELAVTALEQAVEQGENKLILCDFAWDRFAPAYTALRPSAVLRELPE
ARDILAAAGADGQDTGADSLAGRLAALSVQERQEELVRLIRTEVAAVLGYADPADIDPDR
VFKDLGFDSLTAVDLRNRLSEVTGLRLSVTLVFDHPTVTSLVDHVRSELGGTAPVSTSAP
VVPDSPAMPVVDDDAIAVVSMSCRYPGGVTTPEELWGLVTSGADAITEFPTGRGWDLDEL
YDPDPEKIGRTYAREGGFLHDADHFDPAFFGISPREALSIDPQQRLLLEISWEAFERAGI
DPSSLKGSRAGVFVGSSYRDYGSRVQEPTEETEGYLGIGSAGSVASGRISYTFGLEGPAV
TVDTACSSSLVAVHLAAQALRSGECTLALAGGVTVMSTPGAFIEFSRQRGLAADGRCKPF
AEAADGTAWAEGAGMVVLERLSDARRNGHPVLALVRGSAVNQDGASNGLTAPNGPSQQRV
IRQALASAGLNSADVDAVEAHGTGTRLGDPIEAQALLATYGQDRPADRPLLLGSLKSNMG
HAQAAAGIAGLQKMVLAMRHGVLPRTLHVDAPTPFVDWSAGAVSLLTEDTPWPDNGHPRR
AGISSFGVSGTNAHTILEHVPDAYAPDGPDEVGDDAADDGTVLPWLLSARSRAALRAQAQ
RLLEHTDARPGLRPADIAHTLATGRSAFEYRGAVVGDSREALTGGLKALATGGSASGVTQ
GTAVAGKVAFLFAGQGSQRAAMGAELYARYPVFADAFDEICAELDPLLDRPLREVVFAPA
GSDAAALLDRTEYTQPALFAVEVGLFRLVEHWGVVPDLLLGHSIGELAAAHVAGVLTAPD
AAALVAARGRLMQALPEGGAMVALTASEADAMALLAPYDGRVAVAAVNGPASVVVSGDED
AVLDLAEQWRDRGGKARRLTVSHAFHSPHMDAMLDEFRRVAESLEYRAPRIPLVSDVTGE
LATPEQLGSPEYWVRHVREAVRFHDGMRRLAAEGAVTYLELGPDGSLTAMGRDCLAEADP
VGSDDPVDPSAAGPLVPLLRKDRTETRALTDALAQLYVRGTAVDWPTVLEATGRAGQVEL
PTYAFQRERYWLEATAASGGMAAAGLLPADHPLLGAAVPLADTDGVLFTSRLSVRTHPWL
ADHGVYGTALLPATALLELAVRAGDEVGCGQVEELTLETPLVIPAQGSVSLQLTVGAPDS
TGARPLSVHTRPGDTDDMGWTCHARGLLVPTADETEPADTMTWPPAGAQPVSIDGLYERF
AEGGFGYGPAFQGLREVWRLGDDVYAEASLPSEQQAEATKFGLHPALLDSALHSLIFGVL
EGTDQGWLPFSWNGIRLHASGARAVRIRLTPTGNNAVSVRATDTAGQPVASIRSLVLRPV
NPDQVRAARTAHHDDLYRVEWPKLSRPAGADPDGWAVIGAEAPEWAAHGITRSATGLEAL
SREIAEGAGGVATPTVVLAHVPAAPAGLGQPDAVRHVTGHALTLVREWLADDTFADAKLV
LVTRGGVPVSADEVAQDLAHAAVWGLVRSAQTENPGRFVLADLDDTSQDALVAAVASGES
QLALREGRTHIARLAKVPVTEQPGTPDWGRPGTVLITGGTGAIGSVLARHLAAEHGVKRL
LLTSRRGPAAEGAADLVVELAALGAHAEIVACDASDREALARLLGSLPEDQPLTAVVHAA
GTIADGVVDAMTPVRLDTVLRPKVDAAWNLHELTEGMDLSAFVVFSSIAGVFGGMGQGNY
AAANSFLDALAHHRRERGLPAASLAWGLWANKGGMSGGLDEADFRRIARGGIIAFSPAEG
AALFDTASASGEPVVLPLRLDTTALAAQSGADGVPALLRGLVRPAARRSAAAGEAAPDAA
DTLRRTLAGQPEHRRLRTLLDLVRGHAAIVLGFPSPASVDAERGLLELGFDSLTAVELRN
RLGAATGLRLPATLLFDHPTSGAVARQLAVELDLENTDPAADTAGLAELGRLEGALDSGT
ATPELINRLQELIGRLRPDTGAAAEDRLEERMDTASDDELFEFIDNELGMS
>A0A0N1GB10|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MNQEEKVVEYLKRVTADLHRARQRVRDLEAEDRAPIAVVGMGCRFPGGVESPDGLWRLLV
SGGDAVSEFPTDRGWDIEALYDPDPANAGTSYTRNGGFLHDAGDFDAGFFGISPREALAM
DPQQRLLLETSWEALEHAGIDPESLRGSRTR
>A0A0N1GRH5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MPTEEELLKYLKAVSEELHVTRGRLQTLEGRRTEPVAIVGMSCRLPGGVSSPDHLWDVVV
KGEDAIGEFPADRGWDVEALYDPEPGNPGKTYTRSGGFLPDAADFDPAFFGITPREAQGM
DPQQRLILEASWQALENAGINPQTLKGTRTGVFAGSFHHDYDPGGSIGSLISGKISYTLG
LQGPAVTVDTACSSSLVALHQAVHSLRDEECTLALAGGVTVLSTPSVFVEFSRQRGLAAD
GRCKSYATAADGTGWGEGVGMLVLERLADAERNGHRVLAVVRGSAVNQDGASNGQTAPNG
PAQQRVIQDALAAARLTVTDVDVVEGHGTGTTLGDPIEAQALLATYGQGRGEDSPLWLGS
VKSNIGHTQAAAGVAGIIKMVQAMRHGVLPRSLHVDEPSHHVDWSAGQVRLLTENRAWPG
AEGRPRRAGVSSFGYSGTNAHVIIEEPPTRDEEPPTAAPARGGVVPWVLSARGEAALGEQ
AARLLERVTGGAGLDVRDVGRSLVVGRAVLEHRAVVLGSDLDGLAAGLGELAEGRTASGV
VSGRAHSGNSGGAVFVFPGQGSQWVGMARELLEFSPVFAARMAECAAALEPFVEGWSLLD
VVRDGDEELLGRVDVVQPVLFAVMVSLAGLWESLGVRPVAVVGHSQGEIAAACVAGGLSL
GDAARVVALRTRAIVRLAGRGGMVSVLASLEQVEGRLSEGLQVAVVNGPEQVVVSGVPDE
LDAFVAGCERDGVQARRVAVDYASHSAQVEELKAELLDVLSGVRPSSGRIPLFSTVSGEV
IDTAVMDAEYWFTNLRQTVRFDTALESLLAAGHRIFVEASPHPVLLGAVAQNADHSRAAG
VTVVGTLRRNEGEQAQLLRNAAELFVAGVDVDWSPWVAGGRPVELPTYAFQRRRYWRPAA
LTAADVGSAGLGMVRHPLLGAVVHLADSDDAVLTGRLSRDSHPWLEDHAVFGTVLLPGTA
FVELALRAGDEVGCPSVRELTLHAPLSLPEHGEADVQVQVGTGDGTGRPLDIYSRLRRRD
GTSEWTHHASALLTEEGAPPGPTGVLDGTAWPPAGAERLDVAAHYDAMADVGLEYGPAFQ
GLSDVWRLGDEILAEVTLPGRQAEEAPRFGLHPALLDAALQAAAVDALNGSAGRTPLPFS
FGAVTLYGRGASEVRVRITAAGPDTFTVEVADPAGAPVARIEALLVRPVTAGDLAAPQSS
TPELLSFEWSACDRSAYDRSADADPEGAAPEVTLLKVAEPGAGDEVTRARTVLHETLREV
QRWLADHPAGARLVVVTRGAVLTGAEEPDAAVHLAHAPVWGLVRAARAENPGSVVLVDVD
GDAGTGGPDETEVREVLRSGLSELALRNGVLYVPALRRQEAGAAVAAVDALGAGTVVITG
GTSGLGARVARHAAGLGARHLLLLSRRGPLAEGIEDLRAEITATGARVTVRACDVADRAQ
LEQALGELPEDCPVTAVIHAAGVLHDGVLESIDADGLDTVLRPKIDAAWHLHELTAGADL
SAFVVFSSVAGVLGGAGQGSYGAANAFLDALMRHRRRTGLVGLSLAWGLWAEATGMTGHL
GEADLERINRGGIAALATDQGLALLDAALTGEAAGTAATDALLLAVALDGPVLRATEPGL
LPPLLAALFPPRRRAAVNRPGRSAGAAGAAGRVSLDSRDEVVDRLRYRFARTMGFEPAEL
DVAAPLVGQGLDSVMAMQVRSLIEADFGRTLPVATMFNGAAVESIADDLIAGAGSGAAAD
TGAGDDTEEEAPDVVRHPATRDVVRLLRAEQHGTPGVTHHIGLAVRFTDPTTPDRLTEVI
GRLADRHAALRTTIVPDADGGQQLEVRRALAGEPLRWSPVAEGTDVDDRLRELMEPPFDL
AAGALWRFELLAYPSGEQVLVFGAHHAVSDLASLMLVAHELDAGLGADAPPAPSSALVSN
RDIDLLLRAQAARPEGEQNPSADWRADFAGARRLDLELARPRPERRTFRSAMHLVELPER
VRERVAARANRLGITPAAFWLGALTVHLARLRGRDRFVLAVPVDTRLHVGALDAVGYFGL
PIPFAAQVTAGEAGTDVLRRTDSRLGRVLEQGVTFFDAMSALVEEGLYRRNAPLVEVYFN
YMPARTGAARGLEILPAGTGHSDLDLMVTVMPGLGKVSLEYNADIVDESSCAEFGRGFLA
LAEEIADDPDAFVALPDTFTVTPEETAPPKETATPEESAVSPVPEPGSAREPEPGAQIAV
AATFALGNLPAMLTVALESTGAEGGPFDVVEAPYHQVLASLHDPGSVLAQPSTAAGLVLL
RPVDLTRFGPTDGDLLGELAAEYPAALTALADRTRKPLVVAFLPERPDDPERPDDPERSA
DSARSRAWEEQVTARLTDRPGIAVLSSDSWGEDYAADDIFDAHTDGMAHLPFQDEFQAVV
ALRLADVVWNVNRRAPKVIVVDGDETLWSGVAGEIGPEHVDLTGARELLARRLLQWRDAG
VLLALVSNNDEETVHRILDRPDSPLHREHFAAISAAWEPKWTRIVRIAEDLRLGLDSFLF
LDDNPVEIGAVRAQLPEVLCVTCPGAGELADFVGRLWPAVPRAATAEDAARADFYRQEQV
RDEARAQMGFAEFLGNLQLELDIAPVSAETAERTVQLSRRTNQFNLRPRPLDAAVLERLR
QDGEVWTATARDRFGAYGQIGVLAVRADGDALDVVAWMMSCRVLGRGVEDRILQWLADRA
EALGLGTVRLVADNTPRNIPARRLVSRLGGGEVEAPRLETVVPLARLREFRSWDTGTDIP
NTPDTSNTPDASTTSNISDVPETATEVSNV
>A0A0N0MWT9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
FPGGVEDPEGLWRLLSEGRDAVGPFPADRGWDMAALYDPEGTRPGTSSVNVGAFLDGADR
FDAGFFGMSPREALAADPQQRLLLEAVWEALERAGVAPDGLRGSRTGVFAGTNGQDYTGV
LLASDADVEGHVGTGNAASVLSGRVSYVLGLEGPAVTVDTACSSSLVALHLAAQALRGGE
CDLALAVVAGD
>B8E7U3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Shewanella baltica (strain OS223)|TrEMBL
MSHTPSVPNSATESKKDKRLNKRLKDMPVAIVGMASIFANSRYLNKFWDLISEKIDAITD
IPDTHWRAEDYYDADKSKADKSYCKRGGFLPEVDFNPMEFGLPPNILELTDTSQLLSLIV
AKEVLADANLPTDYDRDRIGITLGVGGGQKISQSLNSRLQYPVLKKVFKSSGLSDEDSEM
LIKKFQDQYIHWEENSFPGSLGNVIAGRIANRFDFGGMNCVVDAACAGSLAAMRMALTEL
TEGRSDMMITGGVCTDNSPSMYMSFSKTPAFTTNETIQPFDIDSKGMMIGEGVGMVALKR
LEDAERDGDRIYAVIKGVGASSDGKFKSIYAPRPEGQAKALERAYDDAGFAPHSIGLVEA
HGTGTAAGDVAEFNGLKSVFAQGNDTNQHIALGSVKSQVGHTKSTAGTAGVIKAALALHH
KVLPATINVSQPNPKLNIESSPFYLNTETRPWFQRADATPRRAGVSSFGFGGTNFHLVLE
EYKPEHSRDEQYRQRSVPQTLLFAAANKTALLSELKAALSQSVNTSANTNKSSAASLNAI
AQQYPLRTLASTDARLGFVAKDIAQLQAQLNQSIAHLETNAIEVWQLPSGISYRSHALVA
KNESKKVAALFAGQGSQYLNMGRELACHFPEMRQQVMASDKVFAHHGQTPLSNILYPIPA
FDADAVKAQEAALTNTLFAQSAIGAISMAQYSLLTQAGFAPDMVAGHSFGELSALCAAGV
ISNEDYVELAFARGHAMAQVPSDTASKAVDLGTMFAIILKQKNDIDALNSCLAQFDGVKI
ANYNAPTQLVIAGGTEQTQLAAKAISELGFKAIALPVSGAFHTPLVGHAQKPFAKAIDKA
KFSAPKVMLYANSTGQLHPSDGKAIKAEFKQHMLQSVRFSEQLQAMYDAGARVFVEFGPK
NILQKLVENTLGEHLNELCLVSMNPNPKGDSDSQLRLAAVQLAVAGVALTEVDPYQAVTS
QEIAEREAPSAMNIKLTATNHISAATKAKMAKSLATGSVTSQVQYVDRIVETVVEKEVEK
IVEKEVIVEKVVEKIIEVEANQVAAVEMKQTSPSVVQGLSNQQQATAQLNPSTPNVSGDA
LTAFFSAQSQAAQLHQQFLAIPQQYGDTFTTLMTEQAKMASQGITIPESLQRSMEMFHQH
QAQTLQSHAEFMQLQSSSSQAALAMLNNAPINFSPAVASQPRATAPAPAPFAASTVAHNA
APVAAQAVATRPAINTPVAPVVQTAPVAHAPAATVQVAPAAPVLVMPEMTSVAPATSGLS
AALVQQTMMAVVANKTGYPTEMLELGMDMEADLGIDSIKRVEILGTVQDELPGLPELSPE
DLAECRTLGEIVDYMNSKLPAAGQVVVSTTAPTAPAANGLSAALVQQTMMAVVADKTGYP
TEMLELSMDMEADLGIDSIKRVEILGTVQDELPGLPELSPEDLAECRTLGEIVDYMNSKL
PVVSVVAVAPPANVEATPAQVPANNGLSAALVQQTMMAVVADKTGYPTEMLELGMDMEAD
LGIDSIKRVEILGTVQDELPGLPELSPEDLAECRTLGEIVNYMNSKLPAVGSVIVATHVT
TAAPAASGLSAALVQQTMMAVVADKTGYPTEMLELSMDMEADLGIDSIKRVEILGTVQDE
LPGLPDLNPEDLAECRTLGEIVDYMNSKLPVVSAVAVAPAANVEATPTQVPANNGLSAEK
VQQTMMAVVADKTGYPTEMLELSMDMEADLGIDSIKRVEILGTVQDELPSLPELNPEDLA
ECRTLGEIVSYMQSKLGQNTAANVVNVAVAAEPAIDLPHDLPPHSEVVLKKLPAAAELAQ
KATQLSAQQALPRVFAKDACIIISDDGHNAGVLAEKLHAQGLTVAVVRSPESLVASASPL
NSHIASFTLAAIDDTSISAVINEIKSLGTVAGFIHLQPQHKTSADAKGLVLSSAAKASVE
QTFLFAKHLQPLLTTAATANTSSSFISVSRIDGGFGYLNHSQIARSELNQAALAGLTKTL
SHEWPSVHCRALDIAPALDAKQLANAVIAELFATDKLLEVGVSESGVSEAGATETLARVT
LVAGKADTRHSAANLTSADKILVTGGAKGVTFECALSLAKRSKAHFILAGRSSQQAIPAW
AQGKSNSELKAAAIAHIQSLGEKPTPKQVDALVWPVQSSQEIAAALQAFTAVGASAEYLS
LDVNNPDAIASTIVPITELSPITGIIHGAGVLADKHIQDKTLDELARVYGTKVTGISNLL
AALDLDKVKLIALFSSAAGFYGNTGQSDYAMSNDILNKAALQLAQQLPNAKVMSFDWGPW
DGGMVNPALKKMFMDRGVYVIPLKAGAELFASQLLSNTGAQLLVGTDMQGSAPHDDTSNK
VQETEGSNLKKPEADLTTDASDPHALLNALNPSAVNISAVKLQRTLDPKAMIFIEDHCIN
GNPVLPTVCAIQWMREAAFDVLKQPVKVQSYKLLKGIIFDAVMLEKGALENGAPITLELE
LAPIALTDKAAKDTDECLSGQFSALISFEGRPQYQAILVIDDAVDDAANDYLATNSKATA
FDAQSLAGLSAITTASSLYSDGTLFHGPRLQGIESVVKFDDASLVAKVSLPHFALADCGS
FVPNLAPKGSQAFAEDLLLQAMLVWARLKYGAASLPSSIGEFISHAPFAFGDKGYLVLEV
VKHSGRALEANIALYHQDGRLSCEMSNAKVTISKNLNGAFLANKVAANQTAANKAIESVE
AKVE
>A0A3E2MSF9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium marinum|TrEMBL
MNEQFDKVKEALRRTLIENDRLNRLLTASFEPVAIVGMGCRYPGGLASGDALWEAVLGGR
DVVSSFPTDRGWDVEGLFDPDPDAVGKSYTRSGGFLYEAADFDAEFFGISPREALAMDPQ
QRLILEVSWEALEHAGIDPLALAGSATGVFTGVMYHDYGARLFGTGGASGVEGYLGSGSA
GSVISGRVAYVLGLQGPAVSVDTACSSSLVALHLAVQALRSGECDLALAGGVTVMATPTT
FVEFSRQRGVAVDGRCKSFAAAADGTGWGEGVGVVVVERLSDARRLGHSVLAVVRGSAVN
QDGASNGLTAPNGPSQQRVIRAALANAEVRAAEVDVVEAHGTGTTLGDPIEAQALLATYG
QDRPADRPLWLGSVKSNMGHTQAAAGVAGVIKMIQAMRHQVMPRSLHVDAPSPHVDWASG
AVELLTEQRDWTVQDGRPRRAGVSSFGVSGTNAHVILEEAPAESVPGHGGDSGAASAWPV
VPWVVSGKSDQALAAQAGRLGAYLADHPDLAVADVGFSLATRRSGLEYRGAVIGADHGEL
VAGLAALADGQPSASVVTGRVLAGKTTFVFPGQGGQWQSMAVELLDSAPVFATQLRACAD
ALAPYVDWSLDAVLRGGVAESALTRVDVVQPALFAVMVSIAALWRSCGVQPDMVIGHSQG
EIAAAYVAGGLSLADAARVVTARSQAIVELAGTGGMASVGLPIDQVVDRLTPWDGQIAVA
AHNSPISTVVTGDPAAVQEFVTGCAGEGIFARLIPVDYASHSSHVEAVQDRLIGQLSSIT
PRVGEIPFYSTVTGTQIPTDTLDGGYWYRNLRQRVEFERATTALLAEGARSFIEMGPHPV
LTVAISETAEAHYEDRASVAVLGSMRRDEGDWQRFITSLAEAHVHGVAVDWAAVFAAHRP
RRVDLPTYAFQRQRYWLDARTTGAGDVSSVGLVEVDHPFLRAGVSLGDERGWLFSGRLSA
QTHAWLADHAVFDTVLLPGAALAELALVAGGHVGLDCLEELVLQAPLVPEHAAMQLQLLL
GEPDEENRRQLSIYSRPENVADRGAQQGQWVQHATGTLGAGDSGNGAGFARLSMAWPPEG
AVAVPDDSLYDRLATAGFHYGPAFQGVRAIWRRDDEWFAEIALDSDQIDEATDFGLHPAL
FDAALHVATELLGEQYPPGQVPLPFAWNGVRLPGRGASVLRVALHPTDTGLRLHAVDQSG
TPMLGVDALAVRPIDATQLARSATRREPLHVVGWTPIHTDEALPRQLALLEGNTAFDLGG
IIAGEVGRYPSIAALVDEIRAGGAAPEIVLTAAAVTTEDQSGALGKAARTGLYHTLGLVQ
AWLSQPELLDTRLVFVTQAALTVSGDETPELAAAPIDGLLRSAACEHPGRFAHIDVDDSP
ASRQALAAALSLRQEPRLAIRSGAVLAPRLAQVPAHSTKPGAAPVFDPQATVLITGGTGV
LGMALARHLATHHHCEHLLLVSRRGAAADGARELRAELAGHGCQVEFAACDTADPDQLSA
LLQSIPVEHPLGAVIHAAGVLSDGVIEALGREQVEQVLRPKIDAAVLLHELTQDLDLSAF
VLFSSAAGVLGSPGQANYAAANAFLDALAQHRRRHGLAAVSLAWGLWRQASGLTGQLDQV
DHARMQRMGLAAMATDEGLQLFDLACGRPEPVLVPALLDTNALRAQAHAGILPPLFRGLI
RMPAKRAQAAATLAQRLTEIPQSEWDALLLSEVRSHVATALNYSGPEAIDPIQAFNEIGL
DSLGAIELRNRLTQTTGLKLPTTLIFDHPNPTALAQFLRTQLTETTTCESVHSLNEEIAK
VESLLAAVAMDRKMASRVEDRLRLFSATLHDFLAGIPADISDIDNDLQFESDDELFDILD
DEFGANN
>E3JCX4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia inefficax (strain DSM 45817 / CECT 9037 / EuI1c)|TrEMBL
MTTPDLDRPAAAHAEPGAAAGATERKLRDYLRRAATDLRETKARLAELTAARDEPIAIVS
MACRYPGGVRSPEELWTLLAAGRDATGDLPDDRGWDVEELYDPDPAARGRSYARRGGFLR
DAADFDAEFFGLPPREALATDPQQRILLELGWEVLERAGIDPTTLRGSDTGVFAGVIAAD
YAPDNSPDSAADNGPGSSAVEGYTLIGSTPSVASGRLAYTLGLEGPAITVDTACSSSLVA
IHLAVRALRAGECGLALAGGVTVMPTPRSFVEFSRQRGLAPDGRCKPFSAAADGFALAEG
AGLLLLERLSDARRRGHRVHAVIRSSAVNSDGTSSQLTAPSGPSQRRVIRQALAAAQLTA
ADVDVLDAHGTGTTLGDPIEAHAVLATYGQGRPADRPLLLGAVKANLGHTQAAAGVASII
KLVEALRHGLLPATPHIDAPSPHVDWAGGAVRLLTEASPWPAGGRPRRAAVSSFGISGTN
AHLILEEAPAADTADGPHPADPATPGPSLPWLLSARSPAALRAAAGRLAEHLDAATGLAP
EATAAALLHTRAHLEHRAVVVAADRPSARDAFALLAAGSAGSPALTGEAVGNRRLAVLFT
GQGSQRPAAGRELYETFPVFAAALDEVAGHLDPLLGRRLLDVVFAPAGSEPAALLDQTAF
TQPALFALGTALYRLVESFGVRPDHLVGHSVGGLTAAHVAGVFSLADAATLVAARGRLMA
ELPSGGGMVALEATEAAALAAVAELGLAGRLGLAAVNGPDAVVVSGDLDAALVLEREWKA
RGGRAKRLTVSHAFHSHRMEPARAALREVVAGLRAHPAAIPVISDVTGRVATDASLADPD
YWAGHLRQPVRFHEAVGELDRLGTTTYLELGPDAVLTALAADTLEEHADQDRTDRPRVVA
TLRDGRPEPAALLTALGELHAHGVPVVWDRLLPDSAAARAVDLPTYPFQRTRFWLGRPST
GRARPQLHRLVWEPIATAGASHTGEIARFGDTTVLLAALADGRRLPQVVVVDAPTGPADQ
GGAPPEAAVSVGRTLELLQRWLADDARDGSVLALATRGAVAVEPGADVTDLAGAAVWGLV
RSAQSEHPGRFLLVDLAAGAGQATGDEVVAAVRAALGAGEAQIAIRDGVARSPRLRRLVP
STAASDPGLTAEPTAAPGTAAGPRPLHPDGTVLITGGTGGLGAQVARHLVARHGVRRLLL
VSRRGEAAPGAAELRDELTAAGAAVTIAAADVADHSAVADLLATIPADAPLTAVVHAAGV
LGDGVLTALTPDRAAAVLRPKADAARHLDALTADAELAAFLLFSSVAGILGTPGQSSYAA
ANSYLDALATRRRAAGRAGTSIAWGQWTEAGGMGDRLTPGDAARLRRAGVAPMSVTAALN
LLDEALTTSEPVLVAAHLDPAGPAAAGADVSHGPLRELAAPGRAPTGPGGGPAPRTNAGD
DTIPQLVQALAGRSGQERGQLLLGHIRAAAATILGHPDAGAVAADRGFLDGGFDSLGAVE
LRNRLAVATGLRLPKTLLFDHPTPRALAEHLAGLVGPVGAAPASGPVEDPVAALEALAAA
LAATPPTDDTRAALVTRLESLLAGLSAEPDDLDVASAVSDATDEELISFIDRELGIS
>A0A3E2YJV4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MW-13|TrEMBL
MANEDTLREYLKWVTADLHQTRRKLGELEAANREPIAIVGMACRFPGGVRSPEDLWELVA
SGEDAISGFPADRGWDLTRLFHPDPDHPGTSYASEGGFLDSATDFDAGFFGISPREALAM
DPQQRLLLETSWEAFEHAGIDPSALRGHQVGVFASTTGQDYVSLLQQPPPGTEGYILTGT
AASVVSGRISYALGIEGPAVTVDTACSSSLVALHLACQALRQGECTLALAGGATIMSTPS
AFIGFSRQRGLAADGRVKSFAAAADGTAWGEGVGLLLVERLSDARRHGHPVLAVVRGSAV
NQDGASNGLTAPNGPSQQRVVLQALASARLSPEQVDVVEAHGTGTTLGDPIEAQALLATY
GQGRPADRPLLLGSVKSNIGHTQAAAGVAGVIKMVMALRHETVPATLHVDEPTPNVDWTA
GAVSLVTRVQPWAAGEQPRRAGVSSFGMSGTNAHVIIEEAPAEADPAAADTAPDGDAGRG
AATSAGAGAATSAGDGSAPVDGAGLVPVLLSARDAAALAEQATRWADLVDARPELRLPDL
GWSSATTRARLEHRAVLFAADRADLLAGLRALAAGHDAPGLVTGAGPRGGQLAFLFSGQG
AQRCGMGRDLADAFPVFARALAEVCAELDRHLPRPLAPVLFAPEGDEAAALLNQTLFTQA
GLFAVEVALFRLLESWGIVPDVLLGHSIGELSAAHVAGVLALPDAAAVVAARGRLMQALP
AGGAMLSVQLPAESVRAALTGLDDRVAVAAVNGPTSVVVSGTADAVEDLERRWADQGVRT
KPLRVSHAFHSPLMEPMLDEFAAVLRGVELHPPTLPIVSNLTGEVVDPDAVRTPEYWVRH
VREAVRFADGVDRLCAMGVRTFLEVGPSGVLTALTRDVLAATGRDEGRAATALLRRDRGE
PGSAFAALAELHAGGVDVDWAALFAGTDVARVPLPRYAFHRQRFWPEPPPAPVAATAAGD
DDGFWAALEGADAETLGGELGVDPDDDAVRTLLPALPVLSSWRRSRRERSLADEWSYQVT
WKPVPVADRDAPAGHWLVVLPATDAPAWAAGLADLLPDAAPLTVGAADLDRAALAARLRE
AAGERPVAGVLLVVAGQDRLLPEHPGVTLAAATALALVQALTDLDLVAPLWCVTSGAVAA
APADALEHPLQNQVWGLGRAAAVEQPHRWGGLVDLPATVDAAVARRLTAVLADGGEDQVA
VRSGGVWARRLGPAPAAVDDVPAVDWSAGTVLVTGGTGGLGGHVTRWLLDRGARQVVLAS
RRGAAAPAVADLLDRYGADGRVTAATCDVTDRSSVAALLDSLPGLTAVVHAAGTDQLTPL
TDTTLDEFSHVVAGKVLGALNLDACLADRPLAAFVLFSSISGVWGSAGQCAYGAGNSLLD
ALAVNRRGRGLPATAVSWTAWGGEGGMAAENAATAQLNRMGLPPIDPERALVALDRATRR
PTGCVTVADVDWTRFHPAFTVARPSPLLGDLPQVRALLDAEESAAPAPGAVAEPLRHLAG
LSATDQERDLLRLVNEQTAAVLGHATPDELRGRPFKDLGFDSLTAVDFRGRMNTATGLRL
PTTVVFDYPTPAELAAHLRELVFGGDAADAVAATVVDADEPVAIVGMACRYPGGVGGPEE
FWRLVADGVDAVSAFPTDRGWEIPEGLDGAQAPAGGFLYDVPDFDPAFFEISPREALAMD
PQQRLTLEASWEALERAGIDPGALRGTRTGVFVGASTSGYGTGLTEVPEGVEGYLMTGAA
HSVISGRVAYTLGLEGPAVTVDTACSSSLVALHLAGAALRRGECDLALAGGVAVMATPTA
FQEFSRQGGLASDGRCKSFAASADGTGWSEGVGMLLVQRLSDARREGRRILAVVRGSAVN
SDGASNGLTAPNGPSQQRVIRQALASARLTTADVDVVEAHGTGTVLGDPIEAQALLATYG
QGRDGGEPLLLGSVKSNIGHSQAAAGVAGVIKMVLAMREGLVPASLHADEPSPHIDWSAG
AVELVTRNRPWPAVDRPRRAAVSSFGISGTNAHVLVELPAADDADATPAPAPDPGLLAAD
VVAWPLSARSTAALAAQAARLARHLREHPGLDPAAVAWSLATTRSAFDRRAAVLGAGTPD
LLAGLDALAAGAPAGNLLTGAVAGHGPGPVFVLPDARAALDAAAGLVGRCAVLDDALADC
RQALAPWLDVDPAALLTGADRSWTDRPELAQPVAFAVGVALAAVWRHAGVTPAAVLGHAD
GEVTAACVAGVLSLPDAARVVALRARAVADPADGAADRLRAELTGLAPQPGTARLLSTVT
GDWADPASLGADHWADGVRRPGSLDAAARTAVAAGHVTFVGLSPDPASTAELTGALAAAG
AAAQVLDTLRGDGDGPTRLLAALAAAHTVGLPVDHRRVLAGADPVDLPTYAFERHRFWLE
RTGAHRAVLPAVGLDVVDHPLLSAVAELPGDEGLLFTGRISLTAQPWLADHAVLGTVLLP
GTALVELASWTGRHADAASVAELNLEAPLAIPAEGGVDLRVRVGPADDTGHRPVSVHSRP
DDAADGARPWQRHASGLLAATEDPADAPAAVWPPADAEPIALDGLYTRLAEQGYHYGPVF
RSLRAAWRCGTDILAEVALDADAATDTTAFSVHPALLDAALHAIGASVAGADPDAAQPPA
TGGADIRPGLPFTWTGVTIRPTRARELRIRLTATGSGAVALTVTDTGATPVAAVTGLVLR
PISGEQLSAARRAATRSLHRLDWVTPDAARADGPYRLAVLGDDWPAADRSPDLAALVAGV
RAGAAVPDAVVVTCVGPEPDEPNPARLAHRVSHRTLALAQQWLAEDTLATARLVVVTRGA
VRVDAGDRIADLPAATAWGLLRSAQSENPDRIVLVDADDDRAAADLLPAALATGEPQLAV
RAGQLRVPRLTRLGPPPADRPDPDLAAGTVLVTGATGALGRLVARRLADRHGVRHLLLVS
RTGGDAPGVAALVDELAELGTTARVAACDVTDRDALALLVDQLPADRPLTGVVHAAGVLD
DGILGALTPDRFDAVLRPKVDAAWHLHELTEKLDLAAFVLFSSAAGLFGGPGQANHAAAN
CFLDALAQHRHDRGLPATAMAWGPWANDTGDGQPGHVDEDRMNRGGFVPLAAEEGMDLFS
EALRLADPVVVPVNLDLALIGRHGPAAVPPVLRSLVRPATTGAARAAERDPAAALRDTLA
ATPEADRDQVLSDLVRTHAAAVLGYASIRSIDVERGFVELGFDSLTAVEFRNRLNAATGL
RLPSTLIYDRPTTAALVEHLRGALLAERSTSALSVLGELNKLEHVMRTVADGDADRAAVG
DRLRELLSLWTYTGSAAQDATDDGESLSSASAEEIFSLLDEELGAA
>A0A3E2YF53|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MW-13|TrEMBL
MLASWRRQQRERSTLDDWRYRSVWQPYTGTPVSFLPGAWWVVADERHAADGETAVAELTR
RGAEARLVVLPERLADRAAVAEHLTAATRTADGDTAPADGVLSLLALADGAVDDTQPVPP
FLARSLALIQALGDLDVSAPLWCVTRGAAGTTRGGTVDRPEQSLLWGLGRVVALEHPERW
GGLVDVPATLDDHGWDLLCAALAGLDGEDQLAVDGATVLVRRLVRAPAGAPAADAPDHPG
TTLVTGGTGALGAEVARWLAARGAEHLLLVSRRGADAPGATELVRELTEAGTRVTVAACD
VADRAALAKLLDDVPADAPLTGVVHAAGVLDDGVLDGLTADRIATVLRPKVLGALHLHEL
TVDRELRTFVLFSAMAGQLGAAGQGSYAAANAYLDALAEQRHRQGLPATSVAWGPWAAGG
MAATDPAVEERRRRTGVARLDTAPALAALERCVARREPATLVAAIDWARYVPGFVAVRPS
PLLGGVAEAQRAVAERADDSGASPESLAALLAGQTDAERRKTLLELVRGQAAAVLGHASM
DAVEPDRAFRELGFDSLTAVELRNRLAAATGVRLPATVVFDYPTAAGLAEYVRAAIVDGG
VVGVAPVFGELDRLEAALTGSAPDRSARIRITERLRALLASLNEDDAPAGGGGDTVAEKL
QDATPDEVFDFIDRELGVS
>E0IE70|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Paenibacillus curdlanolyticus YK9|TrEMBL
MNDSIGSGAIAIVGVSALFPGSTDNRGFWNDIMAGNDLMTDIPSSHWLIEDYYDPTPMTP
DKTYAKRGAFLKQVQFDPKEFSMPPSNIPATDTSQLLGLMVAKSVLEDAAQGQFSLIDKD
RISVILGTASASELTVELGSRIQRPVWVKVLRESGLPEDEVQEISDRIAAEYVPWKESSF
PGLLGNVIAGRIANHFNLGGTNCIVDAACASSLTSISMGAMELLAGKSDLVITGGVDTLN
DIFMFMCFSQTPALSPTGDCRPFSDQADGTMLGEGLCMFALRRLEDAERDGDRIYAVLRG
FGTSSDGKSKSVYAPVSKGQAKALRRAYEMAGYSPATVELMEAHGTGTKAGDAAEFAGLA
SVFDDGTRADRQWCALGSVKSQIGHTKGTAGAAGMFKAVMALRHKALPPTIKVDRPNPNL
DISNSPFYLNTKARPWIRGASHPRRASVSAFGFGGSNFHVTLEEYKGPGRQAWKLRTMPS
ELLLFSANNPADLLAQCEELLAGLTDDEGLHAYLARHTQSYYDPKQPARLALVTADLSDL
RIKLEKAIAALRHHPEQRIDDNSGIYYANGAIPGKIAMLFPGQGSQYLNMGSELLLAFDE
ARAVWDRAADVSMDASSSLHEIVYPRPVFTSEELDTQRNRLQATEWAQPAIGAMSMSALH
VLRKAGVQAEHFAGHSFGELSALCAAGVLNEADMLQAARKRGELMAAASAASAGSGAMCA
VFASISQVRAIVEESGLAVTCANHNSPSQVVISGEAEAISRMEGALSAQGISCQRLPVST
AFHSPLVASSVPEFRTYLADCSVEAGRGVVVSNADGQPFPSTPDGLRDQLAAQIAQPVLF
AETVQALYASGVRTFIEVGPSAVLTGLVAQCLAGKDIVAVGTDRKGQHGVHSLWHTLGRL
ASAGVPIDLRSFWEDYKEEGDPRNSHKPAFTIPLSGVNNGRPYPPKGGTPALPKPNEAKA
MINAAPSSGTELRASEAALPNLQQEAAAQRPALAYTAVSQVGAGASGMDLARVTYAEQQQ
AASNIAMSRINDIQGETTMSNYSITTQSVLLGAITEMQRQTMEAHAAYQRAMADSHIAFL
RTAEVSLAGLSALAAGGLGAFAAMPEIAASAAIPAPVAPAAPAYMPPAPVAPAAPAYMPL
APVAPAAPAYIPPAPVAPAAPAYMPPAPAAPAAPAYMPPAPVAPAAPAYMPPAPAAPAAP
AYMPPAPVAPAAPAYIAPAPAAPAAPAYMPPAPATPAAAEAAAPPPSSDVRSVMLEVVAE
KTGYPVEMLDFDIELESGLGIDSIKRVEILSAVQDQLPELPDVQPGELAALNTLGEIVDY
MNQALGKGKEFAGKK
>A0A063BLL2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Burkholderia sp. lig30|TrEMBL
MNTPIAIVGMACRLPGGVRHPDELWELLVEERDAVTEVPPERFGTEFYRHPAKREPGKSY
TFAAGVIGDVMEFDAAFFGISPREAAQMDPQQRLLLELAWETFENAGRRPADMTGSNCAV
FIGVSSKDYGDRNTDDLSIIDAYSATGNTISIVSNRISYLFDLRGPSMSIDTACSSSLVA
VHQACMSIGAGEADAALAGGVNLLLHPYPFIGFSKASMLSPTGRCRAFDASGDGYVRSEG
GALVLLKRLDKAIADGDTIHAVIVSSGVNSDGHSQGGINVPASATQAALLEQVCARGGVD
PRDISYVEAHGTGTAVGDPTEARALSEVLGRGRDPGHPLMIGSVKSNLGHLEPASGMAGL
LKAVLCLKHRAVPATIHFRTPNPNIDFDGGGLRVVDRYTPLSGSGHPLTVGVNSFGFGGT
NAHVLLREADAGPDAAPRAPLAPEHAGLPPLMLGARSPKALHALAGAYKARVEAGESWAA
LAAGAAHRREWLAHRAVVGPASVDEGIDALDALSRGEGAPSVVTGEVPDGGGKLALVFSG
NGAQWAGMGQRLFEEDVHFRAALTELDVLWRADGSPSLVEQLRGGVTAEHLAATEYAQPL
LFAVQFGVLSVLLQRGLQFDACFGHSVGEIAAAWAAGALTLDQAIHVIKVRSGAQAQTRG
TGKMAAVGLDEAAARQLIDTLGLGGELVIAGVNSPQSVTLAGAPQALDAVQAVMLERGQF
FQILDLDYAFHSDRMDPIRALVFDGLDDLRPHESQCLFASSVTGSLLSGQALDAAYWWRN
IREPVRFADATRALLDAGVRIFLEIGPHPILRTYLTQTIDDAKVGGRSLPTLIRNQDGAA
ELARALYAALANGARVDLAALVPAEPDGAHAALPNYPWQRERHEVEQTSEGYRLIHRRRA
HPLLGYRLKDHAAAWENQIDPVSMPMLADHVVDGGITFPGAGYAEMAIAAAQIHFGTPAC
GIENLEIRAPVVFQPQQSKLFRLTIDTQTSGFVIETRGRLSDEPWTVNVTGRLFRIGATP
AVPLVPAETLAGFDTQPPLDAASLYDAAAAIGLGYGDTFRWVTSLRLLPGAVLAELEMPA
ALAGTLPDYALHPAAMDSGFHPLFALLAEEAWAGAASAAYVPVQMGRIAFFGGDPVRRVL
VRIVRRSPHSLVASFTYMDSDAKVVATIDACRFRRVDFTGRHKAEPGRYTFTALARPYDE
DLSAAGLPDPARLVEASCAAVSAQEDAQQRATHLTQVMPLFDVLAASFALRAVEAIGAIG
AAPPPATHNRALFERLVAMLVEDGVLAVVDGRLERGEETLPSIEDLWRGLLALSPAHVAE
LTLLAHCGAALPAVLAGETAADAVLPHGHGDLVDHLHDASPSGAHANAVARACVEAAVDA
WRDDRTLTVLEVVTPGTGLFQPLAPQVQARCDYAVAGSAEQLASVDAAVYPLIRTVELDT
TDGFALATEAGRPARYDVVVVRNMLRAGGEAARLLQAARAWLAPGGILLAVESQPSRFSD
IVFGLDADAWAHERCGLLEAGAIETLLNAEGFDHVVLHSETDLEIEGTPVVIAARRHEGD
APAARVDAEPAWWHVVAGGAAQRALADDLAGALQAKNQAVTCGEHAALADEWAALEQAAG
NRARHVVFVAASADGVPPGADGAAMMDAQESTAIALAQLARALVQLPRQGDLCLWIVTSG
GAPLAAGPDGVAARPEQATLWGFARVLMNEHSELHCRLVDIEPGCAAPPARLVRELLSQQ
SGDETLLASGGRYVTRMAPAALRDLRGEWRAASASARPAYLGFEAPGSLRNLRWFPLPEC
DLGADEVEIEPVAAGLNFRDVMYAMGLLSDEAVENGFAGPTVGMEVSGRIVRAGRDVAGF
KVGDAVLGFAPACFASRVRTRVSAIALKPERLSFDEGATIPTTFFTVYYALHRLAQLRAG
ERVLVHGAAGGVGIAAVQLAKHLGAEVFATAGSREKREFVRLLGADHVFDSRSLAFADEI
LASTEGRGVDVVLNSLAGEAMVRSIDVLRPFGRFLELGKRDFYENTRIGLRPFRNNISYF
GIDADQLMRESPELTSQLFNEVLDLIADGTLHALPYRVFPAERAEDAFRYMQQARQIGKI
LLSFRGGVPAPQAAPGGTLQLEPRATYLVVGGTSGLGFATAAWLVEKGARHVVLASRSAT
LAPELAAQARRWTEAMGVTLTLSSCDVTDAAAVARLVEKIDGASTPLKGVVHSALSIADG
LIANLDDARMRGVMAPKVAGAWNLHRATAGRALDFFVVYSSATTFLGNPGQSNYVAANAF
LESLVRLRRASGLPACFMAWGPIDDVGFLARNRQTRDALEARIGGRSITSREAMSALERV
LLAGAAGEAVAWLDWDAIAKVIPSARSERYVEMRGRDQRDAQRAEGGSLREDILGLAPDD
AQAVVAEALRAEVARILNMTAAKIDPDRSVLELGMDSLMGMELRMAVEECFQVKLSVMML
AQGATVNSIARRIVELIQADARPERPDAELEEQVAALAAAHAVELTDADIRETADGARQA
ALNEEGGR
>A0A655CNM3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MSPTLIFDYPTPATLAEHLDSRLVTASGSDQQSLSDRVDDITRELVVLLDQPDLSANVKA
HLRTRLQTMLTSLTTEDDDIAAATESQLFAILDEELGS
>A0A654ZR51|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MRAVPMWAHPEPLPPVSGLTIAVERWERMVPSTPVAGRHRHLAVLDLGAHRALAQTLCAA
IDSHPDTELSAARDAELILVIAPDFEHTDAVRAAGALADLVGAGLLDYPMHIGARCQSVC
LVTVGAEQVDAADAVPSAGQAALAAMHRSIGFEHPEQTFSHLDLPSWDLDPVLGVSVITA
VLRGFGETALRGSVNGYTLFERTLADAPAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYL
AEHGARRIVLLSRRAADQATVAMLRKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLI
VHAAGSVISGTAPGVTSAAVVDNFAAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHG
VVAYSAANRLLDVMAAQLRAQGRHCVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLR
QMAPQQAIEASLHEFTVDPLVFAADAARLQMLLDSRQFERYEGPTDPNLTIVDAVRTQLA
AVLGIPQAGEVNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKL
EDADERSHTAQKVDISRD
>A0A655D0D0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRFDRAVESAIRCGARAFIEISAHPAL
LFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALSANIVSAAVADPGYPWGDLGGDPLD
GDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVERWERMVPSTPVAGRHRHLAVLDLG
AHRALAQTLCAAIDSHPDTELSAARDAELILVIAPDFEHTDAVRAAGALADLVGAGLLDY
PMHIGARCQSVCLVTVGAEQVDAADAVPSAGQAALAAMHRSIGFEHPEQTFSHLDLPSWD
LDPVLGVSVITAVLRGFGETALRGSVNGYTLFERTLADAPAVPNWSLDSGVLDDVVVTGG
AGAIGMHYARYLAEHGARRIVLLSRRAADQATVAMLRKQHGTVIVSPPCDITDPTQLSAI
AAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNFAAKVLGLAQMIELWPLRPDVRTLL
CSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRHCVAVKWGLWQAPKAGEPARGIADA
VTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAADAARLQMLLDSRQFERYEGPTDPN
LTIVDAVRTQLAAVLGIPQAGEVNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLM
GDITGDGLVAKLEDADERSHTAQKVDISRD
>A0A2K8QY25|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MANPTDKIVGALRESLKETERLRRVNQQLTAASREPIAIVAMSCRYPGDVRGPEDLWELV
TGERDAISGFPGNRGWDLENLYDPDPDRQGTVYATEGGFLHDADQFDPAFFGISPREATV
MDPQQRLLLETSWEAFERAGIHPAALRGSKTGIFVGAAYQGYIPDWPHMPEGLEGHLVTG
ISASIMSGRIAYTLGLEGPAVTIDTACSSSLVALHLACQSLRQGDCSLALAGGAAVMGAP
MGLIGFARQRGLAQDGRCKAFADGADGMGLGEGVGILLLERLSDARRNGHTVLAVIRGSA
INQDGASNGLTAPNGRSQQRVIRQALANAALTAEQIDAVEAHGTGTPLGDPIEASALLAT
YGKDRAADRPLLIGSLKSNIGHPQAAGGVGGVIKMVQAMRHGLLPRTLHAEERSSRIDWS
AGAVELLTEAREWPRGEEPRRAAISAFGASGTNVHTILEEAPEEEPAKAAAEGDTPVGGG
VVPWVLSAKSAAGLRAQAERLLTHVTARPGLSPADVGHSLATTRGRFDHRALVLGGDRDE
LIDALGALASGGDSPRVVRGEGVAATDTRPVFVFPGQGSQWVGMAVGLLDSSPVFAGRIA
ECEAALSGFVDWSLTGVLRGVGPGLARVDVVQPVLWAVMVSLAEVWRSCGVVPAAVVGHS
QGEIAAAVVAGGLSLEDGARVVALRSQAIARGLAGRGGMMSVAESADGVRERITAWDGRI
SVAAVNGPGSIVVSGDPEALRELQAECEAEDVRAKLIPVDYASHSAHVEALREELLDLLA
PIAPRRAEVPFCSTVTGDTLDTAGLDAGYWYTNLRETVELESAVRALSAAGFGTFLEMSP
HPVLTMPLQATVEDAVVVGSLRRDEGGPERFLASLGEAFVRGVAVDWAAVFTGTGASVVE
LPTYAFQRQRYWLEGSSAPAEAEAVDADFWDAVEREDLASLAAALEVDAGESSLAMVVPA
LAAWRRARRERSVLDSWRYHITWQPLGDALTAPHDRSSAGADWLIAAPAGAPEGPRVAEA
LRERGAQVRLVELTEADAVREALARRLDEATADAPPTAVLSLLALAEEPYRAGTAQPLGL
ALNLALLQALGDTGADVPLWYATRGAVSVGRADVLDHPLQALTWGLGRIAAAEYPRRRGG
LVDLPGTLDDRAVARLCGVLAGRLTGEDQVAVRASGVHGRRLVRASVPLTDAATPWRPRG
TVLVTGGTGGLGAHVARWLARGGAEHLVLAGRRGPEAPGAAELAEELRESGVRVTVAACD
AADRDALAALLATLDGDEAPLDAVVHTAGVLDDGVLDTLTPERADGVLRPKVDAALHLHE
LTRDRELSAFVLFSSFAGTLGGPGQGSYAAANAFLDALAHSRRAQGLPATSVAWGAWSGG
GLVDEAVEARLRATGMPAMAPDPAIAALQRALDVADTHVAVADVEWDRLIAATPSLDGAA
VLGELPDARRTDTAAAATGEKDTPLAQRLAGLSAQEAEEALADLVSTEVAAALGYPDTTA
VEAGRAFRELGFDSLTAVDLRNRLNAATGLRLPVTLVFDYPTVTTLARFLLAESGAGETG
ATAPAGPLPATVAVDDDPIAIVAMSCRLPGEVTTPEELWRLLMDGRDAISGFPTDRGWDI
EGTFDPDPDKPGTFYATGGGFLDRADHFDPEFFGISPREALAIDPQQRLLLETSWEVFER
AGLDPAAVKGTQAGVFIGASYNDYGSRFTRAPEEFEGYLATGSASSVASGRISYTFGLEG
PAVTIDTACSSSLVALHQAAQALRQGECSLALAGGVVVMSTLDTFIEFSRQRAMAPDGRC
KAFSADADGAGWAEGVGMLLLERLSDARANGHEVLALVRGSAVNQDGASNGLTAPNGPAQ
QRVIRQALAGAGLSAADVDAVEAHGTGTRLGDPIEAQALMATYGQGRDADRPLWLGALKS
NIGHTQAASGVAGIIKTVLALRHGVLPKTLHADELSPEVDWSAGAVELLTEAREWPETGR
PRRAGVSAFGVSGTNVHVVLEQGPEHTAPVAERSIHSDVVPWVLSGRSETALRAQAGRLR
DHLEERPELRPADVGYALATGRSAFGHRAVVVGAEREELLRGLAELASGTAPETVADGGK
TAFLFTGQGAQRPGMGGELYAAFPVFAAAFDEVCAELDRHLDGSVREVVFGADAEPLNRT
VFTQTGLFALEVALYRLVETWGLRPDFLVGHSVGELAAAHVAGVFSLADACALVAARGRL
MQALPEGGAMVSLQAAEADVLPRLEGHEDRVSVAAVNGPEATVISGDEDTVLRIAEAAGV
KSKRLTVSHAFHSPLMDAMLAEFGTVAAGIGYSAPRIAVVSNVTGEVAGEELCSPEYWVR
HVRRAVRFGDGIRFLAERNVTRFVEIGPAGVLSAMGQECLAHTGTDTDTDTDTDTETGTG
TDAAFVPLLRKGRDETESLLAGVGRVHAHGGAVDWEMVFAGRGARRVELPTYAFQRQRYW
LDAPATVGDVASAGLGPAGHPLLGAAVELADSDGLVLTGRLSTRGQPWLADHAVSGVVLF
PGTAFLELAIQAGDRVGCDRVDELTLQAPLILPERGAVTLQLVVDPPEEDGRRAVNVYSR
PEDAERELSWTRHATGVLATGAAEGSYDLGGAWPPPGAEPIGVEDLYERFTAGGFGYGPA
FQGLRAAWLRGDEVFAEVRLAQEQQSAATGYGLHPALLDAALHTIALGPMLQEGEGRLPF
SWTGVTLHASGAGEVRVRLTPSGTDTVALTVADTIGRPVATVESLVLRKRPERLGEAAGG
DTLYRLDWTPADTSATAPEHPAGHWTLLGDDDFKLVGLDVRTYPNLAALPADPAAMPATV
LVPCAPEPRGVADAVRTATHRALTLLGAWLTEERFADSRLVFITRGAVATTPGADVPDPA
HAAVWGLVRSAQSENPDRFVLVDLDEHEESALALPIALALDEPQLAVRRGDITVARLAAT
PLPASAAPAWDPEGTVLVTGATGTIGGVIARHLVAEGGVRHLLLAGRRGPDAEGASELRL
ELEELGAEVTLAACDVADREALAALLATVPAAHPLTAVVHTAGVLDDGVVSSLTPERIDR
VLRPKVDAALALDELTRDLDLSALVLFSSIAGTFGGMGQGNYAAANAFLDAFAQHCRAQG
RPVQSHAWGLWAQRSEMTGKLAGADLNRLARGGIIPFSSEDGARLFDAARAVDAAVVLPM
RLDTAAGLGARCGEVPPLLRGLVRAAPAKPARRTAAGAGAAPARPEGLKQHLSSLPEAER
GRFLLDLVRTTVAGVLGFDSVAAVEAERGLLDLGFDSLTAVELRNQLGKATGRRLPVTLL
FDYPTSIAIAAYLEAEIAPEAFTAASMTFPELDALESNLAEVAADDEARTTLASRLQGLL
ERLGQGPEDAEDAVVGRIDAASDDEIFDFIENELGL
>A0A2K8RJG4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MNDDKLRTYLKRVTTDLHRASQRLAKLEAKDTEPIAIVGMACRYPGGVNSPEDLWRMVAA
GTDAVTPFPDDRGWDLERLYDPQGDRPDSSYAREGGFLDEISGFEPQFFGISPNEALAMD
PQQRLLLETTWEAFERAGIDPQAQRGAQVGVFAGVQYQDYGSRLRQVPEEVEGFLAGGNS
DSVASGRISYTFGFEGPAVSVDTACSSSLVALHLAAQALRAEECTLAVAGGAMVMSTPVA
FTEMSRQRGLAADGRCKSFAADADGTGWGEGVGMLLLERLSDARRNGHPVLALVRGTAVN
QDGASSRLTAPNGPAQQRVIRKALTNAKLTPADVDVVEAHGTGTPLGDPIEAQALLATYG
REHSPEQPLLLGSLKSNIGHTQAAAGVGGIIKMVQAMRHGQVPPTLHADRPTPQVDWASG
TVRLATELQSWPEVDRVRRAAVSSFGVSGTNSHIVLEQAPAPEEPKETGPAPGADADTGA
APAAVTAPAVVPWTFSARSPRALRARAAQLRALTGLDPLDVGHSLATTRAALEHRAVVLG
GGSDADAALAALANDEEHPFLVRGTVRPTRDLVFVFPGQGAQWTGMAVDLLDASPVFADR
IAQCAEALAPHVDWSLEDVLRSGDFDRVDVVQPVLFAVMVSLAALWQAAGVRPDAVVGHS
QGEIAAAVVAGALSLEEGARVVALRSKALNALVGRGGMTSVALSAEEARRRIGPGLSVAA
VNGPSSVVVAGDTAALDALETWDDVRVRRVPVDYASHSAHVEEIREELLTTLAGLTPRSA
EIPFYSTVTGGLLDTAALDAEYWYRNLRQTVELETVVRALGAAGHDVFVEVSPHPVLTSA
IEETVAGTVVGTLRRQTGGWDRFLLSLAELHVAGVPADLTALLPGGSRVDLPTYPFQREA
YWLEDHSAQQGDVTAAGLGSADHPLLGAVVALADAEGALLTGRLSVRTHPWLADHTVRGA
ILLPGTAFLELAARAGDQVGCERVEELLLETPLVLPEHGAVAIQLAVGAPDPSGRRTITL
HAAPDGTDEWTRHASGTLSAASAAPAADLTVWPPRDATPLDAADMYDRYAAAGFGYGPAF
QGLRMAWRRGEELFAEVVLPDDQQDAARHFGLHPALLDAALHVTGLADAAEARLPFSWNG
MSLHAQGATALRVRIAPAGQDAVSVHVADPAGRPVASVESLALRPPAEDAVRAPGADAVF
RPAWTPVTAAPGTAGPAGTVRVEPGGDVRAAVRHALAEVQRWLADDEPGQLVFVTTGAVS
AAPEEDVTDLAGAAVWGLVRSAQSEHPGRFVLVDTDTEGAEAPLVTGEDQLAVRGARLLA
PRLERARSDGPPAALDGTVLITGGTGLLGSHLARHLVTHHDVRHLVLLSRTGHAPELHAE
LTGLGAEVDIVACDAADRTALAAVIDGLRRPLRAVIHAAGALDDGVITAQTPERVDTVLR
PKVDAAVNLHELTRDLDLAAFILFSSASGVFGGPGQANYAAANAYLDALAQHRRAAGLPA
QSLAWSLWEQASAMTGHLDEADLRRIARSGMPPLTVEQGLELFDRALAAPDPLLVLMRLD
LPVLRASADPVPPLLRSLVRTPARRAVAAHGTAEDTTSLAAQLAALPAADRLGAVVDLVR
TRVATVLGHASADVIDGNRAFRDLGFDSLASVQLRNRLNAVTGLKLPATLVFDYPTPIAL
AEHLLAELGEGRTTATSAVQAVAVDEPIAIVSIGCRFPGDVRTPEDLWNLVASGGDAIAA
FPGDRGWDLDGLYDPEGVRRGSSYAREGGFLAEAADFDPGFFGISPREALAMDPQQRLLL
ETSWEAFERAGIRPQDLKGSATGVFAGVMYQDYAARVTEVPEEIEGFLGTGTSPSVLSGR
IAYTFGLEGPAVSVDTACSSSLVAMHLASQALRSGECSLALAGGVTIMSTPALFTEFSRQ
RGLAADGRCKAFADAADGAGFGEGVGVVLLERLSDARRNGHPVLAVVRGSAVNQDGASNG
LSAPNGPSQQRVIRQALANAGLKPSEVDVVEAHGTGTSLGDPIEAQAVLATYGQDRERPL
WLGSLKSNIGHTQAAAGVAGVIKMVQAMRHGILPRTLHVDAPSTHVDWTAGQVELLTEER
PWDGPRRAGVSSFGLSGTNAHLILEQAPVEEPVAEEAAGAPVVPAVVPWVVSGRSAEAVR
AQAGRLVSLADEDRAAVGAGLAGRSVFEHRAVVLGGPAQELAAGLWALADGEQRADVVSG
VASAVGRTVFVFPGQGSQWAGMAVELLDSSPVFAARFAECERALSPFVDWSPTDIVHSGD
FARVDVVQPVLWAVMVSLAALWESAGVRPDAVVGHSQGEIAAAVVAGALSLEDGARVVAS
RSKAITALAGRGGMVSVPLPVDEVRGLLPDGVSVAAVNGPSSVVISGDPAGLESVLASVE
RARRVPVDYSSHSAQVAEIRQEILRVLEDVSPREARVPFFSTVDVEWADGTGLDADYWYR
NLRQTVEFEAAVRDLAGAGFTTFIEVSAHPVLTVGIDEAVGDESVVSGTLRRDEGGLRRF
LRSAGELFVRGVAVDFTPFFGNTPAYPDLPTYAFQRQRYWLEASAASGDVSAAGLRGVEH
PLLGAALPLADAEGYLFTGRLSLRTHPWLADHAVNGTVLLPGTAFLELAQHAGEQLGCAT
VEELTLEAPMVLPDRGGLAIQVVVGAPDTDGSRRLTVHGKAEHAPADQEWTRYAGGTLTE
ATAPADFTAHTWPPAGAEAMDIDGFYDRMAGNGFAYGPAFQGLRAAWRQGDTLFAEVALP
DEQADHADAYGLHPALLDAALQAAGLGAFFSGDEARLPFVWRGVSLLASGADVLRVRVRP
DGPDSITIAAADGSGEPVVTVGSLVVRPLNPALFRASRELPYHFQWPVLALDTDRTHPEP
EVFAVGAGSAHEVTAQVLARLQDALTEDGTLIVRTRAAVATEPGADVDPAHAAVWGLVRS
AQAEHPDRFVLIDSDEASDHLVAAAVATGESQLALRDGVAHQPRLARVGTGDTLLPPADG
TSPWLLGTTERGTLENLALLPAPELLAPLADNEVRVEIRAAGMNFRDALNALGLLPGEPG
PMGIEGAGVVTATGPGVTGLAVGDRVCGVFAGCYGPVAVADRRLLARMPDGWTFEQAAGV
PVVFLTAYRGLVDLAGLSAGETVLVHAAAGGVGMAAVQLARHLGAEVYGTAGTGKWEATG
LDTDHLASSRTADFESAFLTATGGRGVDVVLNSLTGELIDASLRLLPRGGRFIEMGKTDL
RDPEQVAAAYEGVGYRDFELMDAGPDRIHAMLTEVLGLFEQGVLTPLPTRGWDLRRAPEA
MRFLSQAKHVGKLVLTPPRRLDPDRAVLITGGSGVLAGLVAEHLVAEHGIRHLVMLSRSG
DAPDVPGAEVRSVACDVSDRDALAEVLGSLERPLTAVVHTAGVLDDGVLADLTPDRLDQV
FGAKADAALHLHELTRDQDLAAFVLFSSAAGSFGAPGQGNYAAANAFLDGLAQHRRAAGL
PAQSMAWGMWTQRSGLTARLDDGDVARMARSGMPPLSSEQGLALFDAALATDLAAPVMVR
VDHDALRRQETLPPVLRGLVRAPARRAATGAGAGASLGDRLAAMPEAERQRYALDLVRGA
AAMVLGHASPDLVEAGKAFRELGFDSLTAVELRNRLTKATGLKLSATLVFDYPTPTVLAG
HLLAELAGTRTAAAAPVAAASDEPIAIVAMGCRFPGGVSTPEALWELLASGGDAITGLPT
DRGWNVSRLYDADPDRAGTSYVREGGFLDAVGEFDAGFFGISPREALAMDPQQRLLLETS
WEAFERAGIDPASLKGTPGGVFVGTNSQDYITLLAGDPDAGEGYIATGNSASVVSGRLSY
TFGLEGPAVTVDTACSSSLVALHLAGQALRSGECTLALAGGVMVMATPGGFVEFSRQRGL
AADGRCKSFGAGADGFGMAEGVGVLLLERLSDARRNGHPVLAVVRGTAVNQDGASNGLTA
PNGPSQQRVIRQALANAGLKPSEVDVVEAHGTGTSLGDPIEAQALLATYGQDRDRPLWLG
SVKSNIGHTQAAAGVAGIMKMVLAMQHGTLPRTLHADEPSPHIDWATGQVELLTEAREWP
DANGPRRAGVSSFGISGTNAHAIIESVPPAAAPAAPPATVVPWLLSGRTPEAVLALAEQL
RPLTGENPVDIGHTLATRTAFEYRSVVVGRDAEDWTVGLAALDRPVAAGVGRTVFVFPGQ
GSQWVGMAVELLESSAVFAARFAECERALSLFVDWSLADVVRAGDFGRVDVVQPVLWAVM
VSLAALWESVGVRPDAVVGHSQGEIAAAVVAGALSLEDGARVVALRSKAITGLAGRGGMV
SVPLPVDEVRSLLPDGVSVAAVNGPSSVVISGDPAGLESVLASVERARRVPVDYSSHSAQ
VEEIREEILSVLAGVSPREATVPFFSTVDVEWADGTGLDAEYWYRNLRRTVELEAAVRGL
AGAGFGAFIEISAHPVLTMPIEETAEDVDGDTAILAVGTLRRDDGGLRRFMTSLGTAWAH
GVDVDSAALYRGGRQVALPTYPFQRERYWLAPPSPEVSTDSWRYRVTWRPAVPEARPLPG
TWLAVVPEGHREDAWAAGALRALTERGARVEEYVVPVGTGREELAAALADRARPEGVLSL
LALAERPDPAHPGLTAGLALTTVLTQALHDARWTVPLWCLTQGATSAAGDGEPRHPAQAA
VWGLGRVIGLEHPEFWGGLVDLPTDHDERSAATFCDVLAGGGDEDQWAVRGGTTLVRRLT
RALPDGRPARRAWRPRGTVLLTGATGAVGPYIARWLAAAGAEHLVLAGRRGADVPGAAEL
IAELAESGTRLEYTGCDVTDRTAVAELVARLDAAGTPVRAVVHAAALIQIASLADTSLTE
FEDVVHAKVAGAVHLAELLPDLDALVLFSSIAGVWGSGDHGAYAAANAFLDAYAEHLRGR
GTPATSIAWGIWNTPNLAESAAMPGGLDMDRVRRQGLPFIDPQLAVAALQRAMDDDETVL
AVAEVDWSRFAPVFTSARPRPLLDEIPEVAAQAREETPAAAPVAAQLSEAELVTLVREQV
ASVLGHSGADAVDPRRAFRDIGFDSLTAVELRNRLNAATGLRLPTTVVFDHPNVHAVARH
LRAELTQDTATPVATVVVAAEDEPIALVGMACRFPGGVNSPEELWELLRAGGDVISDFPA
DRGWDLDGLYDPDPDKPGTSYTRHGGFLAAAGDFDPVFFGISPREALTMDPQQRLLLETA
WEAFERAGIDPESQRGERAGVFVGTGHQGYGANAEVPEALQGQMVTGGSVSVTSGRVAYT
FGLEGPAVSVDTACSSSLVAMHLAGQALRSGECSLALAGGVTVMANPEGFIGFSRQRGLA
EDGRCKAFADAADGMGMSEGVGMVVLERLSDARRNGHPVLAVIRGSAINQDGASNGLSAP
NGLAQQRVIRQALANARLEPSDVYAVEAHGTGTTLGDPIEAQALLATYGQDREEPLWLGS
VKSNIGHTQLASGVAGVIKMVLAMRHGILPRTLHVDAPSTHVDWTAGQVELLTEERPWDG
PRRAGVSSFGLSGTNAHLILEQAPVEELVSGEAVGAPVASAVVPWVVSGRSVEAVRAGAA
GLVPLVDEDRAAVGAALVGRSVFEQRAVVVGESAEEFAAGLRALANGEPLAGVVSGAVSA
TGRTVFVFPGQGSQWVGMAVELLESSAVFAARFAECERALSPFVDWSLVDVVRAGDFGRV
DVVQPVLWAVMVSLAGLWESVGVRPDAVVGHSQGEIAAAVVAGALSLEDGARVVALRSKA
ITGLAGRGGMVSVPLPVDEVRSLLPEGVSVAAVNGPSSVVVAGDPAGLEIVLASVERAKR
VPVDYASHSVHVEEIREELLSVLAAVSPRSAEIPFYSTVTGGLLDTAALDAEYWYRNLRR
TVEFEAAVRGLVDAGHSAFVEVSAHPVLTVGIDEAVGDEVVVSGTLRRDEGGLRRFLLSA
GELFVRGVGVDFTSFFGGTSAYRDLPTYPFQRQRYWLERSAASGDVSAAGLRGVEHPLLG
AALPLADAEGYLFTGRLSLRTHPWLADHAVNGTVLLPGTAFLELAQHAGEQLGCATVEEL
TLEAPMVLPDRGGLTLQLSVGAPDVSGRRSLNLYAREEDAPADQEWTRHATGALATGGST
ADALTGAWPPAGAEPLDTTDLYSRFAEQGYQYGPGFQGLRAAWHRGDEVYAEVALPEAQR
DRARRFGLHPALLDAALHALWLAAVGAGPSAGEAGGVRLPFSWGGTSLYASGATTLRVRL
TTTGTDEVAITVADAAGSPVATVESLVMRPLAAGQLEAARVRSLYRVDWHPVTADGTAVP
PYEVADFTGSDDDVHTVAHRALARVQEWLAAEHEDDRRLVFVTRGAAGPDARNAVHASVW
GLVRAAQSEHPDQFVLVDLGPADEVTQWLPAAVAGGEPQVAVRDGAVLAARLVRAAPTGE
EPKWDPNGTVLITGAGGVLGGLTARHLVDRHGVRDLVLVGRSGPDPELVAELTAAGARVV
AARCDAADRAAMAELIAGVPADRPLTGVVHAAGVLDDAPVMSLTPEQLDRVLRPKADAAL
LLDELTRGLRLSAFVLFSSASATFGAAGQANYAAANAFLDALAERRRAEGLPAQSLGWGF
WEQRSAMTGGLGDREVARLTSGGVRPIGSADGLALFDAASAMDDAVLVPIHLDLSPRGGR
VPPLLRHLVRPAVRRAPAVAEGSADAMTFPQRLEGLPEEARRDSLLDLVRSTVAAVVAYD
GPAAVDPEVTFMSLGFDSLMAVELRNRLSATVGTRLTPTLVFDYPTASGLAGHLYDKLGL
APAAAAVAGPEPAGDVDESEVREALAAVSVEQLRTAGVLDVILRLAEEGRQRTTAERIDH
IRSMDVDDLVRWASALGNDES
>A0A445NG81|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces netropsis|TrEMBL
MTQRDPSIPHHLTGRRTPVSSLVEAVRFRAATTPGQTGYVLHHPRDDGSDDVRRLAYGEL
DERARRAAAHLRDGHRTAAGAQTGPRALLLYPPPSADYIAAFFGCMYAGFLPVPAYPPMT
PDQWGALAAVIADCEAEVVCTTADLQEYVTSSLASAGVTTVRTVATDRPAPPLDEAAIHH
PGPDAVAFLQYTSGSTGRPRGVVALQRNVLANLEVIESAFGHGPASTGVIWLPPYHDMGL
IGGILTPLHQGFPVHLSSPLAFLRDPLSWPRLISQVGATTSGGPDFAYALCARKARPQDV
AELRLDTWDVAFNGAEMLRPRTLDDFTSVFAPAGFRRSAFLACYGLAESTLMVTGTPKHR
EPLVLPGDAAVASGEPGDGELVIATPDGQRITDDGREGEIWLRGPSVCEGYWGRPEDSAA
AFGARLADGSGPYLRTGDLGYLHDGQLVVVGRLKELIIVRGRNIAPAAVEDAAWRSAPAL
RPGCVAAFALDGVHGEEVAVVAEVRRRDPAGGGPVEAALFDEAVREVRAAVARACGVAVR
LVVLVPPGTVPKTTSGKVRRSLCRDLLLRGALTALHRADSGGGPAPRPAAARPSHGGPTL
AEAVIRQAVAAVLRVPADTVDRHRPWNELGLDSLGLTELAACLEERTGTEVPVGMLFDHP
GIAALADALERRSRPAATARDGSTATARPAGSPDPAALFAGREPIAVVGMACRFPGGADD
PDAYWGLLRRGLDATGDVTDERARLLGDDTRTGRQRLGALEGVEYFDAPLFAVSAPEARA
MDPQHRLLLETTWAALEDSGTDPLGRRGSRTGVYVGISAADYARIAERSPLSRFSAVGAS
PSVAAGRLAYHFGLRGPALSVDTACSSSLTAVHLAVSALRLGECEQAVVGGVNLVLAPEP
TAALDRLGVLSPSGRCLPFDAAADGYVRGEGCGVVILMPLSAAREQGLPVRAVIRGSALD
HNGTGNGITAPSGLAQRDVITAALRDAGLPASRVGYLEAHGSGTVLGDAVELGSAAVLVD
GRDRPLYLGSVKGVLGHLEAAAGIAGLIKTVLALEHGEIPPTRGERGPNTTADWAGGRLA
VTAEPVPWPAHDDAPRAAGVSSFGFSGTNVHVVLEQAPTPEPHTERLPSPARPDRRFAVP
LSARTDAALRASVERLAAALRRTPHELGDVAGTLAWHRPVLAARVAFQARETAELLDAMD
KWLTDPPLPGDTPLPGDAPDRASAQGPQDPYGAACARFVTDGTLAGIRTLAPEPFRRVRL
PSYPFERRPYWIGGGRRDR
>A0A5B7V3Y1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MSASYETVVQALRKSLEEVGSLKQRNRQLRDASREPVAIVGMACRLPGGVAGPEDLWRLV
SEGRDAVSGFPEDRGWDLEGLFDADPESTGTSYTRRGGFLHEAGLFDAGFFGISPREALA
MDPQQRLLLETSWEALEAAGIDPGSLKGADVGVYSGVFTQGYVAPGAGGVTTEVEGFAGT
GGSTSVASGRVSYVLGFEGPAVTVDTACSSSLVAMHLAAQALRQGECSMALAGGATVMAT
PGAFVEFSRQRGLAADGRCKAFSSSADGTGWAEGVGVVVLERLSVARERGHRVLAVLRGS
AVNQDGASNGLTAPNGPAQQRVIRGALANAGLSPSEVDVVEGHGTGTTLGDPIEAQALLA
TYGQGREPERPLWLGSLKSNIGHAQAAAGVAGVIKMVQALRHGRLPATLHVDAPTPQVDW
SDGAVELLTEVREWPRNGRPRRAGVSAFGMSGTNAHLILEEAPEEPVSEGSAAVGVVPLV
VSARSRTSLAGQAKRLAAYLESGTASGVSLASAAGSLVAGRGVFGERAVVVAGSADEALG
GLWALARGESGPHLVSGSGGAPGKVVWVFPGQGSQWAGMGRELLDSSVVFAERVGECAAA
LERWVDWSLVDVLRGEVEPELLERVDVVQPASFAVMVGLAAVWESVGVRPDVVLGHSQGE
IAAACVAGALSLEDAARVVALRSQAIAAGLAGRGGMASVALSEAEAAGWLGPWAGRVEVA
AVNGPSSVVVAGDAEALDEVLEALSGDGVRTRRVAVDYASHTRHVEDIQDVLAEALAEVN
AQAPTIPFYSTVTGSWVADAGVLGGDYWYRNLRGRVGFGPAVVELLGQGHGVFVEVSAHP
VLVQPVTDAVDAGDVDAVVTGSLRRDEGGLRRLLVSMAELFVRGVAVDWGGVLPATGSAR
VELPTYAFDHQHYWLTPVAEATDAASLGQAAADHPLLGAVVRLPQTDGLVFTSRLSLRTH
AWLADHRVGGVAILPGTGLVELAVRAGDEAGCGVLDELVIEAPLVVPERGGVRVRVTLAA
PGENGTRTVEVYSQREDDADAGDSAGADAWTRHATGLLSATARPDGTGTGIGTGTGTSFD
FAAWPPPGAQPVEVGNFYQALGERGYGYGPAFQGVRSVWRRGEEVFAEVALPEEQRRDAG
RYGIHPALLDAALQAGTVGAAAPAADSAAGGGGEPVLAFAWNGLVLHAAGAAALRVRVAP
SGQDGQDALSVEAADETGGLVVTMDSLVSRPVSADQLGAGTVATSLFHVDWTELPPARGA
APSPPWAPVACAADVALLAGEVPPAGALEAGDGPVVGVLEVVGGDEEDAVLTLTSQVLAV
LQAWLAETALDQSHLVVVTRGAVAAGGEDMVTDPAAAAVWGLVRAAQSEHPDRIVLVDTD
PTADSTVDAVLGAVMASGEPQLAVRGTALSLPRLGRVAGHVTDGPAVFGPEGTVLVSGAG
SLGALVARHLVTRHGVRSLVLASRRGPDAEGVPELVAELTGQGATVAAVACDVSDRDQVH
ALLAAVPEEHRLTGVVHTAGVFDDGLIEALSPERLAGVFAPKVDAVRHLDELTRDLDLDA
FIVFSSVAGLSGGAGQGSYAAANAYLDGLMAGRRAVGLPGLSLAWGLWERSLGMAGHLTD
VDQARASRGGVRAIAAAEGMELFDAAAGSGQALLVPVKLDLRGVRAAAASGTAVPPLLRG
LVRAGRHLARAAGTGDGHRQLSARLAGLAAAEQEAVLLDLVRTEAAVVLGHAGPGGVQAD
IAFRDAGFDSLTSVELRNRLREATGLKLPATLVFDYPTPQALARHLRDEAGGGADGGADG
GAGDVSRTPTRPTAAAADTGEPIAVVSMACRYPGGVGSPEELWRLVADGVDAVCDFPEDR
GWDVEGLFDPDPDHAGTSYTSRGGFLRGAGLFDAGFFGISPREALAMDPQQRLLLETSWE
ALEGAGIDPGSLKGTDVGVFTGVAGQGYGTGVIAPEVEGFAGTGLAGSVASGRVSYVFGF
EGPAVSVDTACSSSLVAMHLAAQALRQGECSMALAGGAMVMATPGAFMAFSRQRGLAEDG
RCKAFADGADGMGLAEGAGVVVLERLSVARERGHQVLAVLRGSAVNQDGASNGLTAPNGP
SQQRVIRKALDAAGLTPTDVDVVEGHGTGTALGDPIEAQALLATYGQGREPERPLWLGSL
KSNIGHAQAAAGVASVIKMVQALRHGVLPPTLYVQEPSHQVDWSAGAVELLTEAREWPRN
GRPRRAGVSSFGVSGTNAHLILEEAPDEPVSEDAAFVGTPVGTVPLVVSARSRKSLAEQA
VRLAAFVEAAAGEVPLTDAAGALVSGRATFGERAVLITDSAEEALTGLRALARGESAPQL
VSGSAGVPGDLVLVFPGQGSQWVGMGRELLDSSPVFVERVGECAAALERWVDWSLVGVLR
GEVEPGLLERVDVVQPASFAVMVGLAAVWASVGVEPDAVLGHSQGEIAAACVAGALSLDD
AARVVALRSQAIAAGLAGRGGMASVALSEAEVIARLESWVDRVEVAAVNGPSSVVIAGDA
QALDEVLEALSGDGVRTRRVAVDYASHTRHVEDIQDALAEALVGVDAKAPEVPFYSTVTG
GWVAEAGVLDAGYWYRNLRGQVRFGPAVADLLGQGYGVFVEVSAHPVLVQPITEIVDGAD
SAAVVAGTLRREEGGLRRLLSSMAELFVKGVRVEWAGVLPAGAGHARVELPTYAFDHQHY
WLTSGLEATDAASLGQAAADHPLLGAVVRLPQSDGLAFTSRLSLRTHPWLADHAIGGVVL
LPGTGLVELAVRAGDETGCGVLEELVIEAPLVVPERGGVRVQVAVGGPGETGSRTVEVYS
QREDDADAGDGADAWTRHATGLLSATARPDGTGTGTGFDFAAWPPPGAEPVELGDLYGGL
AEHGYAYGPAFQGVRSVWRRGEEVFAEVALPEEQRRDAGRYGIHPALLDAALQAGTVGAA
APAADSAAGGGGQPVLAFAWNGLVLHAAGAAALRVRVAPSGQDGQDALSVEAADETGGLV
VTMDSLVSRPVSADQLGAATVATSLFHVDWTELPPARGAGSALSWMSVFAADDVAMLTDE
VASGAAVPMAAVLEAFGGDGEDAVLALSARVLEVVQAWLAGAGLEESRLVVLTRGAVPAG
DGAVTDPAAAAVWGLVRAAQSENPDRLVLLDLDPAADDDPGSVLDTVLAAVLATGEPQIA
LRGTGLSVPRLARVSDQPTDAKASFGPTGTVLVSGGGSLGALVARHLVTRYGVRSLVLAS
RRGPDAEGVAELVAELTGQGAAVAAVACDVSDRDEVKALLASVSTDGQPLTGVVHTAGVF
DAGVIGALSAERLAGVFAPKVDAVRHLDELTRDLGLEAFVVYSSASSVFMGAGSSGYAAA
NAYLDGLMAHRRASGLPGTALAWGPWEQTTGMADTIDDLTRTRMSRREGRGGVLALKSGE
GMELFDAALASGRPLLVPVKLDLREARADAAAGGVPPLLRGLIRAGRQQARATGGTGGDH
RQLSERLAGLPAAERTKFLLDLVRTQAAVVLGHTGPGSVRPDTAFNEAGFDSLTAVELRN
RLRGATGLKLPATLVFDHPTPQALSAYLLGELAVGSASPADPVLAGLAGLEAAIDAAAGD
EEARDRITVRLRELLKAAEAAEAAGGGDAADEDLDTASDEELFAIFDRLD
>A0A5B7UKB3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MEGGPFVTLDEPIAVVGASCRLPGGINGLDELWTALMGGRDLVGVAPPDRFDAERWLSAN
PHRSGKSYTVAGAFLADVAGFDADYFQISPREAAQMDPQHRLLLELAVEALDDAGAVTSS
LAGTDTGVFVSVGGHSYATLQAMRPKLMDSHSALGIMTSFAANRISFHFDLRGPSVVVES
ACSSSLVALHEACEALHRGRVGMAVAGGANLLLAPTDFVASSRATMLSRRGRSQTFSAAA
DGYARGEGGGLVVLKRLADAQRDGDRIHALIRGTATNNDGHTPGISVPDAGAQRSLLEQV
YRRAGVDPGDVVYLETHGTGTPVGDPIECRALGMAMGRSRGAADPLPIGSIKTNVGHLEG
ASGIAGLLKAMLVLRHGAIPASLHATPLSQAIDFTALGLEPVLAARPLEVTARSLVGVNS
FGAGGSNAHAILAAAPSAPPAPAEATGHGDVPVVVSARTRDALAEASERMVRHLEGLDQR
DFYHLAATSAHRRERHPYRAVVLAGTAQQAAERLRALAERSPGSRGTATARGVPRGKVAF
AFSGNGAQWAGMGADLLDGDAVFAAAVARVDALLTPALGWSVEQELRAAKAESSAATEIA
QPLLFTVQVATVCVLAARGFKPEAVVGHSVGEVAAAWAAGALDLATACRVVAERSRAQGP
TAGLGRMAAIGVGGEEARRLLAPYEGRLEVTAFNSDRDLTVGGPQDALEELGAEAARQGI
FFRLLDLDYAFHTSAMDGIRDGLLAALEGVEARTTDTAFTSTVTGGLVDTRTLGAHYWWD
NVRQPVRFGSAVQELLAAGCDTFVEIGPHHVLRGYLTRLCSTVSGQTAVIPTLLRDGDGS
AALDTALAHLLAVGADVVWKEWFPRPARVVDLPTYPWQHERHWHGAPDWWDERLVLGSTG
HPLLGERIPGPEPGWECDVEPERVPWAGDHTISESVVMPGMAFAEMALAAGAEVFGAPVE
VLGLRIDTALTLPWQDDAMDVRLRTSFSPDDGVTQISSTDGDGSSWQAHARAQVRRLLRP
RPGPLDHTASDPPEAGAGERAAQDHYARCADAGLNYGPHLRILHSLRATANAASARYALP
STTTSFHGHPVVMDAALQTALALLPDDGRIYVPVSAGALRYWDTPDALGLIDVRARAVTS
DEGVVDVTVTDLHGAVTLEMTEVRLKALDERRRRPTEYYTTELRAVPLAAVPAPAIAASD
LARATRAERQALPRGWRDSRENGLAARTGELSGHFFAQAVRDMLPGEEEFTLGRLLAAGL
RPDRELLVRSLARMACDAGVMTALGDDAEDPRWRLVAPPRPAAVLQQMTADFPSEAAFLT
LCTLCGSHLAPMLRGDLDPVDLMFNGADRDLIEQVYSSTVPSRLARRNAGIYLREFLARW
PADRPLHVLEIGGGTGGTTASLLPLLPPERTRYVFTDVSAGFFTRAQERFTAYDFVEYRT
LDITADPVAQGFAEGEFDLVIAANVLHVAPRLTQALHHVTSLLGSRGALLAVESSDPRLD
DLCFGGFDGFWTFADAPLRTRSCLLTADRWMPLLAECGFTDATYATQDLDVDDAEDSVIL
ATRTALDTTPVASAPAGQNPVRWLVVAERPEGELAGRLVESLRGSGGPDVAVVSAGDSSR
VEWPPSEGERPSGVVVLLDEAASGSSSGESPPWYGGPSCPSPPGQGLVPSPDQDLIDPML
RRAAMLRDLVAARHRDPSPDPLPLVVVTRPSGALPAPERPLAPSDAAVWGMARSLANEEP
SLRIRRVSLDRGDDPAQDAARLAQVVNADTAEDELVLTRGGCFAPRTRARLPAAPAAASG
PYRLHTDRGGGAAALSWIQDTEGAPGPAPGQIAIAVQAAALNYHDVMTVTGLITEDTDTP
GFQHDRVGLECAGTVTGVGPGVTGFAPGDRVFAFTTTSIASRMTTPAHLAGHIPDGMSFA
EATTLPIAFATVHYGLTDRADLQAGETVLVHGGAGGVGLAVLQHARHVGAQVIATAGTPA
KRRLLRHLGVAHVLDSRSLDFAEQVRRLTSGEGVDVVVNSLTGEAAARSLELLRPGGRFV
ELGKRGFQDNSRLLLKALAANCSYLAVDILKIVAGPPHRARRLTEAVTDLVRRGVYRPLP
HSIHPAAQLQEAFTLFRHSRHVGKVVLSLEERPPVRSAPAPLRLNPHGSYLITGGLNGFG
AATARHLATLGARHLTLVGRRGDSTSESAALLTDLRAQGVDVSVHAADVTDPAALRTVID
SAPLPLRGVVHAAMELNDTLLRDSTDSAFRAALPAKAKGARLLDTHTRHHDLDLFVLYSS
TSSLLGWPGQANYNAANVYTEALARARRQDGLPALAVGWGAITEVGYAARTYSDEYLGRQ
ITTPLAPAAALDSLALLTHSTVDVATVVAHVDWHRVRTATVAGDVPRHAHVLAAVPENTD
DSHTLREQITALDPPQAETLVRDTLTELLARLLRTPTERIDQSIALKNLGIDSLLATELT
TTIRRNLNCELATVAVINATGTDHLARILLPQLMSPNGARRDPDS
>A0A3N6GMQ7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI97-07|TrEMBL
MTPETLLDVLLDAARRAPGQVVVHVRGDGSEEVVTFRRLLDESLRVAGGFRAAGVAPGTC
VPLLAERSEDFQPMFWGALAAGLVPVPLAPDARRVAPVWEHLGCPPVVVDAACADVAGEL
PGPVTVLRLDVLRECRTPAAPVTPAPDDLAFLQFSSGSTGTPKGVELTHATVVANLRQIN
AASALCEQDVLVSWMPYFHDMGLIGTHLAPLAARAGQVKIGPLSFAKNPRLWLEVADRHR
ATVLSAANFALALTVRRVPGHVLAGLDLSAVRLILVGAEPISATVWRDFAAAMRPARLDP
RAATPVYGLAEATLAVTFPPLGEVAVPVRLERAALGRGVAVDLASAGDAVEVMDVGLPVP
GCSVRVTDDARRPLGDRRVGHIEVRGPQVARGYHRLPEATAQSFADGWLRTGDMGFLRDG
RLCVSGRHKDVLFLDGRTFHAPDMEEVASASPGLPPGSPVVVGSTDPVTGGERVVVLVPW
ARPPRGATAVLDLVAQRVRTALGHDDVRVLALPPSSFPRTTSGKLQRQRMRARFEAGAYR
PVASSGTPAAIAATGLVPGGPAAQLPPDGPGERRTPPGPEEPGSAVPRAREDVRRLVRGV
WSRVLGLPEESFADRDGFRALGGTSLKAMEVLAELEETLGVTLAPSVMRHDTVAALTGRL
LTEVDEVTAPHRPAPDGEPAPPPSDDASSATAVVAMACRFPGANTPEEFWELLTAGRDLV
TEVPPDRWGSQVPGSTDDGPLSATSEGPERRWGAFLEDPAAFDATHFGIGGEEARTLDPQ
ARIFLELAHEALERAGYAGPRRRGLRIGVFAAVGESGYRQVLADHSPSLAASATALTGNL
PNLIAARVSHVLDLDGPALAVDTACSSGLVALHLARRSLADGECDIAVVGGVNLHLTADG
YRALEAAQALSPTGRSRAFSTAADGFVPGEGGAALVLRRLNDTRRDGDDVLAVVRGTAVN
NDGTSLSLMAPNPLRQREAITRAYEVCGVDPASVTYVEAHGTGTAVGDPIELRSLAHAFP
ARPDGRPRLLGSVKTNVGHLLNAAALPSLVKVVLALGHGRLPASLHHTPPSPALGRAGFA
LVTETGAWPSDGPRRAGVNAFGFGGTNAHAVVEQAPARPAAHGPRDDAGGPHLLTLSADS
APGLDAWASRLLAHLRDHPELDEGDVSRAAATARDEGSHRLAVVADGDLPERLAAAVASG
DDRLAGVAHGRVSNRPRTVFLFPGQGALRPAQGRALYATAPVYRDTLDEASAQVGAVHGR
ELTSWCVDAGVDARAQAATEVAQPLLVAHGVALARQLLAWGVRPDALVGHSVGELAAACA
GGMLTLADTLTFAVERGRLMGVSTPPGAMVAVRGADEEEVAALVAAAAGELAVAAYNGEG
RLVLSGSPDAVARAVERLSARGAAVRALDVTRAFHSPLMQPIAHDLAEAARALEGAMGGP
PVMSTLTADWLPRLGPDHWREHALRPVLFGRAVTRLLDEGYDTFVELGSPGSLAGLVRAA
ATRRRTAGADGSVSTAARGPVRTASGATMPADSTDGDVLVLPAPPEAEPSAALPEGGAGG
GRELLGTVARLWVRGAVLHRTRSDTGQRRVPLPPYPYQRRRHWPGAAHHGLLHRVGWEPA
PLPQKAAGPVLVTGPDPAAVDELGRRLADQGVGTTVAPGTRPQAVVLLAGPATGGTSADI
ERVQGELVSAFNEALALLDLTGARRLLVVTEDAHATGHGPERPDPVQAVLGGLALAVPSE
SAGVVANWVDLSSLDDAGQRLRAVLAEAAAPQAAGAVAWRSGQRLVRTVAGEAADPPDSR
VLDRLPADGTFLITGGAGGLGSALARDLAGRGRPVLRLTGRSPHPPEGLLEELAALGADA
RYHRADLTSRDDVEKLVAALPAPDAVFHAAGVVHPGSLRETKAEETTEALGAKTLGTVLL
SEALRRHGHSPGVCVAFSSVSSVLPGLAGALGAYAAANAFLDSFAAAERQAGRPWLSVNF
GPFARTGLAAPLAAGPHTRDARDGDRPLATAPALAALRSACGGEATQWVLADRTPRPDRT
VRPDRTSAQPRLPQGPLPAPRLSVAHTSLAAGRDASAAGDEVTSPSGTAAVLRELLAQSL
GVPASSVYDDVSFLSLGLDSLGAVDLVKRLERRTGRSLPATLFFEYRTVRELAARLDAEA
LSDPAPRAGEAEAALSPVLAADQSSFPLTPVQLALYTSSRLHPGVPARGHLRMTVHGPLD
THVLGRALAGLAERHGMLRLRIDDSGAEPVQRLAPAAPLSTWYEVRACGAGQVADIETAL
CNQPFDLASEPPVRAVLLRQEPGLAHLLLVVHHAAADGYSLNVLAEELWSSYTALWRGER
PAPAQDATRFAAYAATTARSSGSTASDADRRYWAGRLAAHGEEPLRLPYDGDPDALPSGP
LVQHYGSLDAALTAGLERTAAAHDVSLFHLLLAAYVRCLARWAGRPDVAVNVARAGREQR
FPDMDRLVGPLADTLPLMCEAEPGEPVVALAQRLRRIWLESERHAGLSSLDLAGLLPGDG
RRTASPAGFSFARFPVRPADDCPVEVRAGAAGTGSAATRLSLLCWADGPVLRMSWNFPQP
LFAPRTVARLDREFRDELAALGALPEERLPLPAAPAPPCGTDAPLGVVARLLRQFLSTPG
ATAVEAGGTTLAYADLDRASHLLATRLRDGGVRAGELVGLLTEPGPDTVIGVVGILRAGA
GWVPLDPTYPPARLADQLQRAHVRTLVCHGPTLDTAGSLGHVRTVRADGPPDVRVDDLAH
VPVPDPTAIAYVIFTSGSTGRPKAVPITHGAMENYLDWALGAFGYGAGDRLAQTASPCFD
ASVRQLLAPLLVGGTVVTVPRDLLRDPELLLAYAERTRITVWSSVPTLWEQLLSAAEDRE
RRGAGRPDLSALRWVHVGGEALPAAHVRRWFDLFGDGQRIANLYGPTETTINATCHVITT
RPADDVRTLPIGRPLTGTDLSVVGPDGVACRADEPGELLIAGVGLTPGYLGEPELTARAF
TLRDGQRWYRSGDRVRRRADGVLEFLGRVDGQVKIRGNRVETGEVEAALQAYPRIAQASV
VAREGRLLAFVTARPGAGRPEPRAVRRHLATMLPSYMIPPRITVLDELPLTGTGKVDRHA
LVGPPAPTERGGVSAGDAVPRSERAPAGRRESRPGPAAGTAVAAGGSTRPTTPTEIQLAS
IWAALLDVDAVSREDDFFDLGGDSMLVLQVFARLGEVRAPLPRPTVIYEHRTLAELAAAV
DATAVDAPASERHGIPAATRAATDHADPFPLTPAQRGFLLAEALAPGGGGSWPARLRLSG
PLDPEVFQASVDLLVGRHGMLRTVFPAGARPPIQQELPPSLRLRVDFETLSDPAEVDVRA
AAEAQRRFEPWAWPLLRLRVLTLEEHEHVLLVHAHHLIGDGYSAALLVQELTAVYDRLAA
GRAADLPAPRATFRDHALSSAAAEPDNAPGTVARRARVEATYRPPVLRTTGGGGGAGADA
APFHPAGFVLDAGRTAALRALAARAGATLYAPLLAAYHQQLAQLTGRADLIVGLAVSGRD
RPLTDVHRILGPFATAVPVRPVAPRGDGRAEEDSVDAVRRIVAEAEEARRHEDIVPRNAD
GLPLTSQFFFTFLDFSVLSSAHGQVLTASWDDGDSAFAPPSSATDVFVAVRPEGAGLHVT
VRGSAAAFSPSAVKGFARALRERLVRAVTPHGSSRPAAPRGTMDAALVGYLPAPGHLARV
AGLPEDAWQRDDLRAMLFPDGAPRLLETVRTPLGTSGFVCVPLFADELARDPGLAAHAAR
AVSLASSLGARCVSLAGMIPSLTGYGFDVLRYAEGPAAVTTGHAATVVSVVRTVHAALDA
TGRELADLDVAFVGLGSIGASSLELLLSRASRPPRRLLLCDAPGSAPRLRRLARRLQERG
AAGEVEVAESGPALPDAVYGAGLLVTAVSSSGDLLDVDRLAPGAVVVDDSFPHCFDTGRA
LARMRERRDVLLVGGGLLHLGDLTRETAEGLPAAAAAGYTAQPWLDGTLASCRVESLLHA
ADPGLPLVHGLVDGAALAYWEGVERAGITAGPLHLLGHAVGAELLAGVRAAS
>B8LUA8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MSVISVFFGPQWTKATPDDLAVLQSTISESPDLKFLVDSVRELGSLWSTLVEECPTLRQI
SGHQEIENLEAFIACQGDLKVFQEPNISSGNILRNALTVISHVVQLWQLRTTVQIDAFPT
LTSKLVDQGQAQLGDVQGFCIGFLTAAAVASSKTPDEFQKNACIALNLAVCVGALVDLNE
MKCEDPSQRTTSLAVGWKSQTEYEELQGILEGSDGYISCVTDHNRATVSASNAKTELIVS
SLLKADLSVQPIKLRGRYHHSAHSSVLSSLSHLLATDKRFQFSIADHLTKPLRSNVDGEV
ITTGDLHNIALESLLLHRSEWYKIASSAITYLKETDTRPVSIVAIGYEKSVPRSLSSMIY
NDQKVHTNNHIYSESHTANHVNSSFTPSEIKTPASESGFNDNAIAIIGMACRFPQADSLE
EFWKLISSGMSVVRPLPEDRFRASDLRREPKGPFWGNFLDNPEAFDHRFFGNSGREAKSM
DPQQRLLLQVTYEALESSGYFAPKLLEQTTDVGCYMGVGSVDYEDNVASHDATAYSALGT
LRAFITGRVSHYFGWSGPSITYDTACSSAAVAIHSAVKALNAKECSVAVAGGVNVITSPK
LFQNLAAASFLSPTGASKAFDASANGYCRGEGSGVVVLKPLTTAIADGDSIVAVITGSAV
NQGSNSTPITVPSEDSQRALYRNVLSVSGTNPADVTYVEAHGTGTPVGDPVETESIRKTF
GGAQRTHKLFIGSVKDNVGHTESASGVAGLLKTLLMIKKRVIPKQANFSRLNPKISPLMP
DRMAVPESTQMWTAPSLTAVVNNYGAAGSNAALVVQEYRHSEEAYPKTALASFSGREFPF
LVSAKSAESLQAYCSKLKFSLHENAEYRASDDVVDLAFNLATKQNRDLEYFYTFTATNIS
SLEKCLGEASHSPSSHFQKLPSNTLPVVLCFGGQNGRTVGLDEGVYKSNRLLQIHLDTCD
SVCSTLGLPGLFPGIFETGPVEDLVSLHCILFSLQYATAKAWLDCGLKVDTLVGHSFGQL
TALCVANSLSLTDGFRLIAGRARLIQEKWGAESGAMLSFEGESEQIDKLLKLARQQNSAF
AADIACYNGPQSFVIAGTSASIEQVEELCASREWRSLLKVVRLRSTHAFHSQLVESIMPG
LKEITESLSIKPPTIRIEACSDCEGWSQVESTKIAQHSRMPVYFTKAVERTVERLGPCVW
LEAGSASPIVPMARRILTSKGIEKGNMFQPTDLRGHDAQDRLARITSNLWAAGVKTQFWS
FHSSQRFAYSWINLPPYQFEKTAHWLEYKKPEPVLPQTISAKLPFDGPGTLLRLLESHTG
KSLFEINNLSEIFQLCTTGHAVMAQSLCPASLYVECAVQAATLLLESRSSSIAPRVGDLK
ISSPLTKNTERNVFLQLTRNTNQGDQEWIFTLFSSSSNVAGDSPVTHATGAVDLFPFNKV
SEQSRLKSLQRLVARSRYEDILNFPGSNSLAGSVIYKVFGQIVVYSPYYRGVQKIVARDN
EAVGHVFVPDNQPQALASRGSCDPITLDNFLQVAGIHVNCLVEREDREDVYVCTEIGELL
MTEAFVEKREMMRSWNVYTTFEESAGKSVVNDVFALDQETGELMAILMNAKFQSVPVKAL
ARTLGKLNGRPKPTVSNNDRMEVRSNGLQDNRREERDTKSKMLTNRNGLHKRNEPQSLEL
VQAMFSDILAVPIEDIKADATPDDLGIDSLLVTEVLSEIKKRFNVTITVADFQTVNNLST
LASLLEPNRPVIDRQSLPAPLSKQPPVSMNGLSTHEQSESLMPQVQNMFAEVMEMPASEV
LPATSLQDLGVDSLMITEIANEITNRFGITVPIPELQDLKDVHALASRLQPHSTKTHSKP
INGHAGYSSSAKTNGVSQMNGHSTPRALNGESRPNLTLTADESFQKVRRNYDTITKITGF
SDFCRDVYPAQMELVAAYVVEAFTKLGCPLAELRMHEKVPEVSFLDVHAKLKRQLYRILE
EGGLIQRDTDVGTYLRTDIPTPSTPSNILHNDILNKFPQHVSEHKLLNSTGSKLAECLVG
TADPLGILFGSSKARLLMEDVYTNAPMFKAGTIQLAQYLVNVFDKIDDPSRVVRILELGA
GTGGTTKHLVETLVGQTNQPFEYTFTDLSSSLVAAARKKFAGHNFMCYSVLNIEVDPPAD
LLNQYDIVISTNCIHATKNLTNSCSHIRQLLRPDGILCLVELTRNLFWFDLVFGLLEGWW
LFEDGRTHALAPETLWKKHLQQAGYQWIDWSESPSDESNIIRVITASPGAIGSRRGENGL
SDKNDIDVETVEFKREDDLPLLADIYYPPRNGTQQQTLAVALMIHGGGHIMLSRKDIRPQ
QLQMLHDAGFLPISIDYRLCPEVTLPAGPMQDVCDALEWVRSTLPTLALQRDDIRITGKE
VVAVGWSTGGHLALTLGFTAPARNIAPPEAVLAFYCPTDYEDPFWSQPNVPYGREMAPPL
YETQYDLAKGVFDRPITAYNISPAKRALGGWMDTTDPRSRIALHMNWRGQAVPILLNGLS
PFSPTLSRDLATMLPKPTNEQVRSISPLAQIRQGMYKTPTFLIHGTKDDLIPWQQLQRTF
ECLLENNIPADLRILDGAVHLFDMFPDYVRDDTAYSAVRDGYSFLRLHVERRKSA
>A0A3S4RS05|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium chitae|TrEMBL
MTAGRINNPGDPHDAVVIVGMAVETPGGVATADDYWSLLSEQREALGPFPTDRGWALAEL
FEGSRREGFKQIHNLGGFLTGAAEFDPEFFGISRREATAMDPQQRVALRLAWRAIENSGI
NPDDLAGHDVGCYVGASTLEYGPPLSEFSHHSGHLITGTSLGVISGRIAYTLDLAGPALT
VDTSCSSALAAFHTAVGALRSGDCDLALTGGVCVMGSPGYFVEFAKQHALSDDGHCRPYS
AHATGTVWAEGAAMFLLQRKSAAQRAGRPILAEVRASALNSDGRTTGLTAPSEAAQARLF
RRALDQAGLQPTQVDVVEGHGTGTSLGDRTELHSLAATYGATAPGAGPVLGSVKSNVGHT
QAAAGALGLAKVLIAAERGTIPPTLHVDERSGEIDWDSQGLRLAEKLQPWPATNGSRIAA
VSAFGMSGTNTHVIVEMAQ
>A0A3N6HR65|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI96-02|TrEMBL
MISAHATLAQNGPMDDMTLTHLLLDAAAEAPEQVIVHVRGDGDGDGDGGELVVTFRELLA
ASLRVAGGFRAAGVAPGTRVPLLADRSEDFQPMFWGALAAGLVPVPLAPDARRLLPVWEH
LDRPPVVVDAACASLLAELPDEVRALSLDVLREGPALWEPVGVGGEEVAFLQFSSGSTGA
PKGVEVTHAGVLANLEQIRAASALGADDVLVSWMPYFHDMGLIGTHLAPLAARAKQVKIG
PLSFAKRPRAWFEVAHRHRATVLSAANFALALAVRRVPGEAMAGLDLSSVRLVLVGAEPI
APAVWRAFACRTRAAGLPPTALQPVYGLAEATLAVTFPPLGEVAEPLALDRAALSRGRAV
DRAPGDGTVELMDVGRPVADTIVRIVDDAGRPLGDRRVGHIAVRGPQLARGYHGLADASA
DAFADGWLRTGDLGFLRDGRLCVTGRHKDVLFLNGRTFHAPDTEEVAAATPGLPAGAPAV
FGSTDPVTGSERVVVLIPWARPPKDAGEVLDRVAVRVREALAHDDVRVLALPPGAFPRTT
SGKLQRQLLRARFEADELPGGGNAVSAAAFSSQGPVGARPGPAVPAAAVAGGGSRAPRSR
KGAERAVREVWGRVLNLPGEAVGRNDRFAGLGGTSLKAMEVLAALEEVFSTTLPPAVMRD
HDTVAALAEHLLSAAGPALPQAEAEAVPPSRAQGEPDAPTYAAAGGRRSAAPTAVIGMAC
RFPGAATPDAFWDLLVDGHDAVTPVPPGRWEPETGAGATSGAADTGAAADARGDADAGAG
AGAGAGSGTAASAEDRRGTARWGAFLDDPAAFDAAYFGIGGDEARALDPQARLFLELAHE
ALERAGYAGPRRRDRRIGVFAAVGESGYREVLDRAAEAGAPLSAAALTGNLPNLVAARVA
QCLDLDGPALAVDTACSSGLVALHLARRSLLDGECDLAVVGGVNLHLTSTGHRLLEAAQA
LSPTGRSRAFSGAADGFVPGEGGAALVLTRLDAARLADDPVLAVVRGTAVNNDGRSLSLM
APNPLRQREVITRAYEESGVDPASVSYVEAHGTGTPVGDPIELRSLAHAFPVPSGGEPRL
LGSVKTNFGHLLNAAALPALVKVVLALGHRRLPASLHHLPASPALGPVGFSVVTETREWT
SSGPLVAGINAFGFGGTNAHAILEQAPPPSSTAPRDDAGPHLLTLSARSAAGLRVAAANL
ADRLRSRPPLSEGDVCRTASTSRDDGPYRLAVVADGDLRERLAALTAAAPQPSQPQPQPY
GMSGGPGRSGAFTPGEVRSRPRVVLLFPGQGTPRLGREGGLYRTAPMFRETLDEASALVG
PLHGRSLLDWCLDPDPTPEPASESETEAGPDAEPDAEPERRALTTEVAQPLLVATGVALA
RQMRSWGVEPDAVAGHSVGEIAAACAAGMLSLSEAMRFAAERGRLMGAFTEPGAMLAVRG
GDEEAAALVAAAGGALAVAAYNGPGLLVLSGAVAAVEEAARALDARGVAVRRLRVSRAFH
SPLMGPIADPLSDAARGLAPRAGVLPLLSTVTAEWQPVLDPEYLRDHALRPVLFGAAVER
LIREGYDTFVEVGRGASLAGAVRAAARRGAPDRSGPPDDRTDRFGPSDDTTDHFEPADGR
AADGRGGAEEAAARVTVVPALPDHGTAGGARRPGGEGRGELLATLGRLWTLGTPLDRTVL
DAGRRHVPLPPYPFQRSRYWPLPPSRPLLHRVGWQESGTPPTCAGVGSVLLTGPDAAAVD
SLGEQLTAEGVRLRPKDGTPPDAVVLVAGPAPALTDADALDRAQDAALSAFRTALALLDD
SGAHRLLVLTEDVHVTGAATERPRPVHAVLHGLLMALSQETPGLAATSLDLCSADTAADR
LTAVLFELREELPAGLRVDRTAEPVTAVAWRAGRRLLRTVTPLAVTPLAVTPLTGTPHAG
APHALTPLTGTTPSPLPPDGSFLITGGGGGIGAALARELATLGRPTLVLAGRSPRPPAGL
IEELTALGATVDYRAADVSVEQDVDALLAGLPGLDAVFHAAGVVRPGTLRNKTAEEMTRV
LAAKTRGSLLLSLALRRHGLSPDVCVAFSSVSAVLPGLAGALGDYAAANAFLDAFAASER
RAGRPWQSVNLAAVAGTGLAAGLRTDSGPGTGTGRGRGSGARTYSAPVSVSASSAASRAG
SRPLTTADALAALRTASGIDAAHLMIADLTPPPSPVTSVGAVPDPAGTSAVVEAPVPVTD
RTPSGIEATRPASAGPGHAPLLRRLIAAALRLPTAADVSEDEPFLSLGLDSLAAVDLVKQ
LEHELDASLPATLFFEYRTVRELAAHLDASLSTGRNTGASTGAGTNTGASTGAGAGTNTG
ASTGTGTGTGAVVADGTPFALTPLQLAFHAGGRLHPDIPARGYVRQSVSGPLDEGLLARA
LAALAERHPMVRLRITTAPAEDGRTVPVQYVAPSAPLSDWYEVRACPEGVEKLETELANR
PFDLSAEPPLRAVLARENPDLAHLVLVLHHAAGDGYSLNVLGSELWSLYTDLALDREPSL
PAPGADFARYTAVAAEERSSAAFAADERHWAERLASRHEVLRLPYDGDPADAPSAPLLTH
PSALAPEPAAALRELAAAHGVSLFHLVLAVHVRCLARWSGQREIAVNIARARRETRLPGL
DRLVGPLADTLPLLCSADPDEPAPALAERLRDIWLETERHATPAGLDLVRLLPGGDGPRT
VSPAGFSFARFPAARDARCPVTVRATAAGTATAATRLSLLCWEDGTTLRFSWNFPVRLFA
PATVARLARDFEAELIALAGRRTAQSQQSTQSQQSTQATRTVQTARIARTAPAPGSEAVP
VSRRDTGSATIVDRLLARFRTVPDAVAVDTGASTLTYAQLDRASRALADRLVGRGVRPGS
LVALLTAPGADTVTAVVAVMRAGAGWVPLDADHPTARLADQIARSGVRTVVCHAATRAAA
DALDGVVLVPLDEASPAAPAAPNGRVDADTTAYVIFTSGSTGRPKAVPITYRSMENYLDW
AVRTFGYDRDDRLAQTASICFDASVRQLLAPLLVGATVVAVPRGLVRDPDLLLTHVERTR
ITVWSSVPTLWEQLLTAAEERVRRGLPRPDLSALRWIHVGGEALPPTHVRRWYDLFGGGQ
RVANLYGPTESTINATCHIIDARPGDHVHRLPIGRPVAGAEVRVAGPDGEPRKPGEAGEL
LIAGVGLTAGYLGEPALTEAAFTRQAGRRWYRSGDLVRSAADGTLEFLGRLDDQVKVRGH
RVEPGEVEAVLQTHPDIARAVVLVRDGRLVAFVTARPGTKAADAVALRVHLARTLPPYML
PARITRVDELPLTGTGKVDRQRLLATTATPTATATATDTDTDTGTATAAAVASADAANGN
GVPDRTSRRTPPRTATEVRLAGIWSALLQVGEVCREDDFFALGGDSLLVLEVFARLAERG
GPLPRPTVVYRHRTLAALAAEVDAAARTEVANADTPARAAATTSGAPTTGGGEHHPGPTP
YPLTPGQRGFLLAEAIAPGAGSSWLTRLRLRGPLDPGRFQAAVDTLVARHAMLRTVFPAG
ARPAVQQELPASLRLPVDFETLAGPHQVEERITAERARRFELWAWPLLRLRLLTIAPDEH
VLVVHAHHIIGDGYSAALLVRELMAVYDAATRSERAELPVPRSTFRDYAVHLAGRAENAD
GTEGPIGTEGTDGTEGTDGTEGTDGTEGTDGPEGQEAAARWAWLSAPYHRPELRAEGTDG
VARTGDAVSSDDRMRTGVRHAPFHSRGFDVGTGQVDALRRLASDAGATLYAPLLTAYYRA
LAARTGRADLVLGLAVSGRDHPLPDVNRVFGPFATAVPVRPAGPGSGRPAGADFGDDLRR
MAAEAVAARTHDGAVPSLPSGLPLTSQFFFTFLDFSALGPESGQTLTVTRDDDADSEFTP
PAIGTDVFLAARLDAGRLRVTVRASAGALSARELADLADAVRDGLAEATARPAEDRLTLA
PGALEQESAARRAGEVDAALVGYLPSPAHLARLAGVPATALPREELRSLLFPDGRPRLLE
TLSTPLGRSGFVGVPLFADELAAGESLLGHTVRGVELASSLGARSVSLAGMIPSLTGYGF
DVARALGGEAPAVTVTTGHGTTVVSVVKTVHAALAAAGQDLGDLTVAFVGLGSIGSSSLE
LLLSRAARPPARLLLCDVPGSGPRLKELTVSLRERVAVGPVEAVESAGGLPPEVYGADLI
VTAVSGGGALLDIDRLRPGTTVVDDSFPHCFDTGRAIERMREKRDVLVVGGGLLDAGAGE
RRAADGLPAAAAAGHLAQPWLPGTIASCRLESLLHAAGAGAPAVRGPVDGPTGLAHWAAA
EATGTRAAPLHLLGHVVDTDALRGFSRFSRRG
>H1KTI9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Methylorubrum extorquens DSM 13060|TrEMBL
MTHRKDIAIVGRACRLPGAQNVEGLWQLLTEGRCAVSRIPEDRWSLQAFGHPRAQERGKS
YTWAAGVLDDIWSFDPGVFGISPREAEQMDPQQRMLLELTWEAFEDAGLRPSAVAGSHIG
VFVGASALDYGNLRILDPSSGDAYAATGNTLSIISNRISYIYDLKGPSFTLDTACSSSLV
ALNAAIAAIEAGQVDTAVVAGANILASPFNFISFSNAQMLSRTGLCQAFSSSADGYVRAE
GGVVLILQSAEAAARSGRAVRGVIAASGVNSDGRTTGISLPSGHAQGALLEQVYRDAEID
LDKLAFVEAHGTGTPVGDPIEAGAIGSKLGKPRQTPLPIGSIKTNIGHTEPTSGLAGLLK
ASLALEHDLLPPSLHAAELNPDIPFEAMKLAVNRAPLALARTKAERFAGVNSFGFGGTNA
HVVLTDAGPVAAANDAGPAPEILLLSAQSRAALNDLALDYAARFDGAAPAEAARVT
>A0A1D2I417|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. AVP053U2|TrEMBL
MLVEVSAHPVVATGVRETVEDAGVAAGVVGTLRRGEGGWERFTLSLGEAWAYGADVDWDV
FYAGTRPRRVDLPTYPFQRQHYWPRFADASGDVTSAGLESPDHPLLGASVELAGGDGLVA
TARWSLRSQPWLADHAVSGTVIVPGTALVESVIRAGDVLGVGSVDELTLQAPVVLQERGE
VQVQIGIGDADDSGRRPVTVHTRATGPDGDTEDLWTLRAQGTLAEPGTPAVAGPEDFTAW
PPPGATALAADGFYDLLAGRGYEYGPVFQGVRATWRRGDDVFAEVVLPDQVRGDAARFGI
HPALLDAALHAAGLAPGGDDRTVVPFAWSGVSLYATGATALRVRISPAGEDTVTVHLTDP
SGAPVAVIDALAVREVAAETLDPSARAARDWLFHLDWTPLTSAVTPADATRWAVLGTPDA
PVTAPDDTGTTPLSVLADLTALDDATGQRPTAVLLFAGQDAPAAARPDDDTPAAPDTVLG
EVLTTVNDWLADDRTAEIPLVVVTRGAVATGPGDPAHDLPGAAVWGLVRSAQSQHPGRLV
LADLDVHEDSWRALPAALATGEPQLALRQGTAHAPRLARPRTADTLTAPAGTGAWRLDIP
VKGSVDQLELVPCPEITAEPAPGHVLIEVRAAGLNFRDVLNTLGMYPGPAVLLGAEAAGV
VTATGPGVTGLAPGDRVMGLVTGGFGTHAVADARMVAPVPDGWTFTQAASVPVAFLTAYY
GLRDLAGLTAGESVLVHAAAGGVGMAAAQLARHWGAEVYGTAGDHKRRLLRAEGWADDHL
ASSRTLDFEDRFRETSGGRGVDVVLNSLAGEFVDASLHLLAPGGRLVEMGRTDVRDPDQV
TLDHPGVALYQAYELREAGEDRIREMFADLTRLFADGSLRPLPTVTWDVHHARDAFRHMA
QAKHYGKIVLTVPRAWNPDGTVLITGGTGTIGGILARHLVARHGMRHLLLTGRRGPDAPG
AAGLRDELTGLGAEVTVVACDAADRDQLAATLAAVPAAHPLTAVVHAAGVLDDGALEHLT
PDRLRTALAPKADAARHLHRLTHDLDLADLVLFSAGAGVFGNAGQANYAAANTYLDALAH
RRRADGLPTTSLSWGLWADASAMTGHLDDTDLARVRRSGVLPLSAADGMALFDAALTEQR
PHLVPVRLDTGRLRTGDGEIPHLLRALYRGPVRRTAEAGAATGTDGLRLRLAGLSADDRL
TLLRDLVATHAAAVLGHTDPDQLHGGRAFRDLGFDSLTAVELRNRLNAATALRLPATLVF
DHPTLAELAAHLDGELSGGSPATAPAAPAPLPAAARGDEPFAIVGMACRLPGGVRSPEDL
WRLLADGADAIAEFPGDRGWDLDGLYDALPGDQVTSRTREGGFLHDAADFDADFFGISPR
EALAMDPQQRLLLETAWETFERAGIDPRSVRGSRTGVFAGLSSSDYLKRVAHVPDEIAGY
VNNGNANSIVSGRVAYSLGLEGPAVTVDTACSSSLVALHMALQALRAGECTMALAGGVTV
MSSPEIIVDFSRQRGLAADGRCKPFAAAADGTGFSEGVGLILVERLSDARRNGHQVLAVV
RGSAINQDGASNGLTAPNGPAQQRVIRQALADAGVSAAEVDAVEAHGTGTRLGDPIEAQA
LLATYGQDHDPERPLLLGSVKSNLGHTQAAAGVAGVMKMVLALRHGLLPKSLHVDAPTPH
VDWSAGAVSVLAEATGWPEPATPRPLRAGVSSFGISGTNAHVILEQAPAETESAVEPESA
VDDAPEARADRPLPWILSARSDAALRGQARALLAHLDAHPGLAPADIALSLVTRRATLER
RAVVVATTTGDFRAGLAALADGTPSPAVTSGGRGAGRDRRAVLVFPGQGSQWAGMGAELL
DTSPVFAARIDACADALAPHVDWSLTDVLRGTDGAPSLDRVDVAQPALWAVMVALAEVWR
AHGLRPAAVLGHSQGEIAAAAVSGALSLEDAARIVAVRSLAIARELSGHGGMAAVTAPHD
DVTALVTDLPGVSVAAVNGPSSVVVSGDTDGLDSLLATCEERGVRARRIPVDYASHSAHV
DRLAETLPAALDGIEPRDGDIPFFSTVTADWLPGTALDAPYWHRNLRGTVRLQESLRGLL
DQGHDVFVECSPHPVLTAGIEDTVTAAGADAVALGSLRRDDGGTDRVLTALASAHVAGVP
VDWRPAVVHGRPVDLPTYAFQRERYWLEATGTQADPTGLDTVVRLADGGAVLGGGLSLTA
QPWLDAHRVHGTAVVPATALLDWAVRAGDETGSPTVTTLDEHTPVAVPERGRVDLQITVS
APEGTGGDPGRRTLTVHSRVPDPDGTDVPWTLNATGTLTAGGPAPAPAGPDTWPPAGARP
ADPARAHDRLDRSGLDTGTAFRTLRAVWQHGTDLLADVELPEDARADAGRFRAHPALLQT
ALALAATPEHATAPALPYRWQDVTTYATGATRLRLRLTGDGGTWTVHAHDGTGAPVLTAT
AATRPATPDRLPSATAPDALHRVEWTPWTDDTDPADLTGPWAVVGSPGRLTAALERAGAT
VHVHATLDDLTAALDSGDTEQPALVVVPHTHDNATAGAAARDTASAAHTSAHRALHLATT
WLSDPRHTATRLLVVTEGALATGPDDSVPALADATVWGLLRSAQTEHPGRFLLADLDPNT
DLPATDTTDGDRADASATALIAAVAASDRTGEHQFAVRSGTVTVPRLVRADRDGTTPADS
TPWGDDTATGTVLVTGGTGALGALVARHLVARHGVRHLLLTGRRGPDAPGAADLRDELTA
LGAEVSVVACDAADRDQLAATLAAVPAAHPLTAVVHAAGVLDDGLLDTLTPERLDHVLRP
KADAAWNLHELTRDTKLSAFVLFSSYAGLAGGPGQANYAAANAFLDALAQHRRARGLTAV
SLAWGFWENRSELTGALDGADLARLERAGIRPLTSDQGLGLLDAATALDTAHLVPVRLDP
RVLRAGQVPPLLRALARPAVRRAADTATTGGPQDFRRRLAALSGPRQQALLHRTVLGHVA
AVLGHASAEALDSGRGFLDLGMSSLTAVELRNRLNAETGLTLPTTLIFDHPDPAALVRHL
RDELGTGPAGSGDADQPVFAELAGLEAALNGTELDDQDRARLAKRLRALQWKLDATTETP
GDERDDSDLDTTTDDEMFDLIDNELGLA
>A0A077PXQ4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Xenorhabdus bovienii str. kraussei Becker Underwood|TrEMBL
MGNNFTGLEVAIIGMAGQFPGADNIRDYWEMLRDGKEGVSRFTNEILKSNGVSEEYYLNK
NYIPAKGVINKPFHFAADYFGINHSDAKKTDPQIRLMIESCWQALKHANIDTETNPGQIG
VYAGASSQWSWFKALNTEFNSSAEQFHVATLNDLSFCTRISYLLNLRGPSITIQTACSTS
LVAVHTACQALQAGECDVALAGGVSITHPHQSGYLYQEGMINSPDGKTRVFDANACGTVF
SNGVGVVVLKRLSDAIEDNDKIYAVIKGSAVNNDGSDKISFTAPSVLGQQNVIRSALDFA
EVTPDQISYIEAHGTGTLLGDPIEISALNAVFKNSQSCAIGSVKSNVGHCDAAAGILSLI
KSALCVYFKTLVPSIHFEKANPKLELENTPFYVNTETKPWHSSDNELICAGVSAFGVGGT
NAHVVLQEFPMRTETVSVEDLEYEELPNRIEFKPAIAAETTDVLHAEVESDSVFVDDEID
IEGLPQNLLKIFQEYFSNQKISKNDNFFDIGASSLDIVQLHEKINNTYSVNLSISDFYRY
TNCQKMTEKLLGMIGNKSQGQPKKSKVTKKRKVLNNKNRTYQDYPEHAIAVVGMSGRFPG
SKNIQEYWNNLLQGKEGISFFTDDELIDAGISAHTLKAKNYIKAKGIVADSLSFDPTAFG
YTARESQYMDPQFRLLHEVTWQVLDDAGYGNPKYRPVTGLFASSGSNHAWLDLLKEEVQD
TTEQFGVALLNDREFLTTRIAYKLNLTGPAVTVQSACSSSALAITLACQSLQINQCDLAL
AGGVSVVTPIKSGYTYAKGMVNSADGHCRPFTQDASGTVFSDGIGMVALKRLDDAIRDND
HIYGVIAGYGVNNDGHEKAGFTAPNADGQAACVKQSLKMAAIQASDVEYLEAHGTATRVG
DEVELEGIKDALGVTEINARDCFIGSVKSNIGHTNTASGVASFIKTLLALKHQKIPPSCH
GTENKHTSLENTRFRLTDVAADWVSHGGVRTAGVSSFGIGGTNVHITVQSIEEQPASSQC
QAELITLSSKSREGLVKTMARLGDFLDEEQHSYSLSDIAYTLQVGRGDYDYRTSLVAENV
EALKEALHSLKDSNTLPEALPDQTSGIVFMFPGQGSQYVNMAKDLYQELEIFKTLLDECH
ERLSSQFSIDLIGLLYSWDSEEDSEKLQNTQITQPVIFAISYSLAKTLELLGIEAKAMIG
HSIGEYVAATMAGVMTLDEALKLVATRGIIMQECEPGVMLSVAAGRDDLEPFLTDKVALA
TVNSPNSCVIAGSQADIEKVQQRLVDKNFRTRLLKTSHAFHTPMMKPGAEKFKAALAEVN
WQKPTKAYISNVTGQWITPSQANSVDYWVEHLCQAVEFHAGIMTCLEKPGLNVFLEVGPG
RTLSTFVKQIAASDANISTFNVMRHPLEAENDRNYLLKLVGQLWMRGSSINWPLLYQNTH
PKRISLPGYQFVGESMAMGTSVLAARGSEKESETKIQKNQISEWLYTEAWEDISLPDEAT
RSDIRVALCFVPDITWCQPLCNSLKLDEKSIKFVLPADAYTSAENVITLVPGDKRHFGKL
IDELKQDALLPDSIIFAWPLSGQSDLETSWFSVITLIQSWTTSGSMTDFRLLLANTKQPE
HTMLNGLVKVITQEVSKCHPRLVQISPLESIERQCEILTGELLATDERFIVNRTQTGRST
LTYYKLKAGLLKENTLLKNGGVYLITGGLGDLGLLFAEYLIKEYGAKVILSGRRALPGKH
EWKQLASIDNSEAEILQRLDELSELGKGEVAYYSSNVSDKHEMQVLLDAIEEQYGCLHGI
ICAAGVTRGNSFQGINKLTLEDCTPQIETKVEAYKILAELTENKPLDFCLLCSSIASVLG
GLSFSAYSSVSSFADAFAKQQNSQGKPWISVNWDGWVFERNNSGDPIGSSLDQLLIEPDE
GLKILECALQSPLRGQLIISTGDLDKRFEQWVGGHLKPFKLNESNHSQRAVVSKAQIVGT
IVSVWQDFLKITNISRDDNFFELGANSLDMVQVNKRLTDALDMDFSVVDMFSYPTSELLA
DFIVNQYGITHETGEQAEHSDTLNQHRDPSAQLDQSSTPIDRQIAIVGLAGTFPGAENIH
EFWENLTFGKESVTTFSKEELSEEGIDSGLLENPNYIRAKGVFPNAGEFDAEFFGYTPYE
ARQMDPQVRALHTCCWQALQDARIATKDNRAKIGLYASASGNLQWLAQAMATAEGSAGQY
SAMTVADKDYMSTIVSYKLNLTGPSMVLSTACSSSLVAVNEAVKSLRAGECDIALAGGVS
ITLPIKAGYVFEEGMIHSKDGKCRAFDIQASGTVFGDGVGIVVLKPLKQALADNDNIYAT
IIGTAINNDGGMKVGYTAPSTKGQVEVIQSALRDANVMAESIHFVEAHGTGTTLGDPIEF
NALKQAFSTDKKNYCRIGSVKSNIGHLNSAAGIAGLIKATLAVKNRILPPTLHYARPNKE
IDVANSPFIVNNQYTELNDTRNPIRAGVSSFGIGGTNVHVVLEEAQVNKDKSFNKKVDNR
LPIVLSAPDDKSLQCYKQQLKTFVENNQQQMSVSDIAYSLMQREPMASQFVASACDYDAL
IKALSSGEKDNVKVKPGTTKRKVVFLFPGQGAQYVTMGHELYHSNGLFKEWCDKGFTLAD
KYCSIDLKSLFHSRDEDRNLYNTEFAQPLLFIIEYALAQVLKSYGVTPDAMIGHSLGEYV
AAALAEVFSFEDAIKMICARGKLMQSTEDAVMLSVMSSSESVKEILTGSLEIALDNSSDL
CVVAGSDSDISSFESDCETKSIKTKRLRVNKAFHTRYMEPVLGDYAGIIREIAFNKPQIA
FISNVTGKWAETDKVVEYDYWVNHIRQPVRFKESITEVLKEGNCLFIEVGPGHGLSTLAE
NHSDYHANHICISCFDRKNEEINKHSELVQKLGKMALLKIDVNWHAEMADLQPRLVHLPP
TPLRGTKYPTDIKRLQALFSGNKNLGYQADKPEEQVSQSKAGSNPHPKAKRSVIDELSAI
WKLILGVDTIKEDDDFISIGGSSLSAVQVIAKAKSVNLPVNMSMLLSGQTLVQIRASLQS
DDETTHKGWQFNEHFSPEMYPGSASCLYSAVREKLKHEHGLTSDDAIMQVVDGSPLLGIG
VQQFENDTKIVSKPVNYGILSGWPSLQECYSFSYDKQFFEDYEAYRHYCESELALGHLVI
VTGSDYYLPFSPSYGLPESEYIKRPLFENIELGDDDIIPHAFVLVGKTPSGYQIYDGSFQ
YFGEITEQEFEKTVIGFKGLDFMQSHEVYNKSRSFMMITVTCDGKFHKDNDLKEQTLNRL
VTDFQTKQAIESDESHLSYYVGLTALDKLIENPGLIANSSNFDLEEIFSRWYQQMLLLRK
FLKISKPEVSTECDHAFSIISEELEKVVACCKNSSDDKTIIDSLLLVKSNLSDIIKNLS
>A0A0N1H7I1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OV450|TrEMBL
VAGVHGELSEDWGTPEYWTRHLREAVRFSDTVQYLQGRGVETYVELGPDAILTALASATV
GDVEGTAFVSSLRRQRPEARELLAAVGRVHNQGVAVDWAAYFGATEDRWADLPTYAFQQQ
RYWLEATTGEGAGLGAAGLETVGHPLLSAAIASADSGEVVLTGRLSVDTQPWLADHDVLG
SILFPGTGFVELAVRAGDQAGCDTIEELTLHAPLILPERGGAAVQVWLGAPDASGRRTVS
IHSRDENAVEPVWTRHAEGTLVNGSAVPGGAGLTEWPPPGATPTTVDGAYELLLERGYHY
GPVFQGLKAAWTSGESLYAEVSLPEQAHADAAQYGLHPALLDAAMHVALIDDGSSTDEST
VLPFSWNDVTLHAGGAPALRVCIAPSGPNTVTVTVADAEGQPVLTVGSLVSRPVSQEQLG
GARPESLFEIAWRPLPASAVASADAVAEQHVWGALPEGELSGAVVFHVPATEGSLPEAVR
SAAAQTLAVVQEWLADERFAETTLVVATRDAVVVDAAEGIDLAQAPVWGLVRAAQAENPG
RIQLTDLTASTDDLAAVIASGEPESAVRPDGLRIPRLTAVPAPVSEQGPIALDPAGTVLI
TGGTGGIGAHLARHLVTVHGARHLVLTSRRGPEAEGAGELAAELGELGAEVTITACDVAD
PANITTLLASIPAEHPLTGVVHAAGTGDNGLVATMDAGRLDRVLAPKADAAWHLHEQTRH
LDLPLFALISSAGGLTLAAGQANYAAANTFLDALATHRHAQGLAAQSLAYGLWASTGMGQ
YITDTDVKRMERQGLPPLQPEEALALFDAAYASGRPATVPLHVNRTALAARTDELPALLR
SATPAPQRRNVRASASASGAGAGAANDLAARLAGKTEEERDSALLDLARAHVAAVLGHES
ADAIAPDRAFQELGFDSLSAVDLRNQLKAATGLRLPATLVFDYPNARAVAKYIGESLGGA
AQSATTRPAAGTARAQAEDDDQIAIVAMSCRLPGGVTSPEDLWQLVVEGRDAVSGFPVDR
GWDVENVYDPEPGVPGKTYSNEGGFLYRAGDFDPHFFGISPNEALIMDPQQRQLLEVSWE
AIERAGINPHTLKGSKTGVFAGVMYHDYGQGTEAAATTGGSLISGRVSYTLGLEGPSMTV
DTACSSSLVSLHLATQSLRSGECSMALVGGVAVMASPDMFVEFSRQRGLAADGRCKSFAG
AADGAAWSEGVGVLVIERLSDARRNGHPVLAVIRSSAVNQDGASNGMTAPNGPSQQRVIQ
SALEKAGLTTADVDVVEAHGTGTRLGDPIEAQAVLATYGQGRDEDKPLWLGSLKSNIAHT
QAAAGVAAVIKMVQALRHGLMPKTLHVDEPTPHVDWSEGNVKLLTEAVEWPAGDRLRRAG
ISSFGLSGTNAHVILEEAPAAPAAPVVGTDETPRELPAVPVVLSARSPEALAGQAERLRA
HVGGHEDLSLTDLAFSTATSRTAHEHRAAVVAETREELLAGLAALAEGSAAGVVQGVVRE
GKSAFLFTGQGAQRLGMGRELHAAFPVFADALDAVVAALDVHLDMPLYGVMWGESAGDEA
LLNSTAFTQPALFAIETALFRLVESWGVRPDFLAGHSIGEITAAHVAGVLSLEDAARLVA
ARGRLMQALPAGGAMAAIEATEEEILPHLGDTVGIAAINSPRSIVVSGTEEAVDAIQAQF
TELGRKSTRLRVSHAFHSPLMDPVLAEFRAVAESVTYQQPKVPVVSGVHGEISEDWGTPD
YWTRHLREAVRFSDTVQHLAAKGVTRFLELGPDAVLTALTQVSLDGQNVLVEPVLRRNRP
ETRSLLTAVVHLHTTGARIDWTAFYAGAGAQRVDLPTYAFQHERFWLEATPATDVAHHGQ
TSVGHPLLSAAITLAGSDEAVLTGRIAAATHAWIGDHDVLGSVLLPGTGFVELALRAGDQ
VGCPVLEELTLQAPLVLPRHGGVALQVSVGAPDDTGRRTVRVHSRHEDAPADTPWLLHAD
GLLGTRAAAAGTDLTVWPPTGATAVDVSDTYELLQGRGYHYGPVFQGLTSAWTSGEDIFA
EIELAEQAHGDAEGFGVHPALLDATMHALGLGGSGSDDEPGEGAQPLLPFFWEDVSLYAV
GATALRVRISWTSENTMSLDAADATGAPVLSVKSLTFRPVSQEQLGGARPESLFEIAWRP
AAAPADVVAEQHVWGELPEGELTGAVVFHVPEGEGPLPQAVRSTSARTLAVVQEWLAQER
FAQTSLVVATRGAVVVDASSDAIDLAQAPVWGLVRAAQAENPGRIQLTDLTGTEDGLAAV
IASGEPESAVRAGGIRIPRLAPVTATTEAPVVLDPEGTVLITGGTGGIGAHLARHLVTGH
GARHLVLTSRRGADAEGAVELAEELSALGAQVTLTACDVADPANITTLLASIPSEHPLTG
IVHAAGTGDNGLIATMDAERLDHVLAPKADAAWHLHEQTRHLDLPLFALISSAGGLTMAA
GQANYAAANTFLDALATYRHALGLAAQSLAYGLWARTGLGQYVSDTDVKRMERQGLPPLQ
PEEALALFDAAYASGRPATVPLHVNRTALQARADRLPALLRPATPGTQRRTAGAKGVATE
LIWLRIGQAPEEEQEAALRELVQKRAAHLLGHSSPTAIDVERGFLESGFDSLSAMELRNA
LMQDTGLRLSPMVVFDSHSPAQLAKVLLAEYAEQGPGTTATEATASGSAAASPGSAPAAR
PPRGAGETLRDLFHGAVVSGHADKGFDLLRAAAAVRPSFETAAELERVPAAARLADGAEG
PHLIFVNTPMATGGAYQHARLVSHLQGKRKVSALPVLGFDASESLPATPQAAVEGLARTV
LEAAGGEPFVLIGYSSGGTLAYATAGHLERAYGIRPHGVVLLDTYNVHDGESEGVPMDGL
ALGMFDKEAAFGEFDTTRLSAMGRWVELVPNLPLESVAAPVLFVQCTQSFVPDGDDPSPE
LTQGKAEPWDPAHTLRPVAANHFTIVEERADDTARVLEDWLASGIADAPDAAQTADQTQK
AM
>B2IYP5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MNKIDTKQNNINQLQRALLALKEMRGKLEAIERAKTEPIAVIGMACRFPGGADNPDAFWQ
ILQHGVDTIQEIPQERWDTEAYYSPNPDAEGKSYIRYGGFLKDIDLFDANFFEISPREAV
STDPQQRLLLEVSWEALENAGQCIEQLSQTQTGVFIGVMNNDYSRLYAGNSNSIDTYFGT
GNSFSFISGRLSYILGLQGPSLVVDTACSSSLVSLHLACQSLRSGECDQALAGGVNLILS
PDTNIFLSKMRAVAPDGRCKSFDASADGYTRGEGCGVLVLKRLSDAVAAGDSILALIKGS
AVNHDGPSGGLTVPSGPAQQKLLRQALANSRVAPQQVSYIEAHGTGTSLGDPIEINALAS
VLCEQRSFEQPLVVGSVKTNIGHLEAAAGVAGVIKVILSLQHQKIPPHLHLKQPNPHIPW
QELPLAIPTTPKPWHSENNTRIAGVSSFGLSGTNAHLVIEAAPLEEAGGAGEQGNRGEEI
RERPLHLLTLSAKHPQALQQLAQNYIKYLSSHPDIALGNITFTSQVGRTHFSHRLAIIAA
DYQQMQQQLQAYLNDTDDFSIHHGHSSQQTKKIAFLFTGQGSQYRNMGRQLYETQPSFRQ
TLDQCDTLLQPLLGESILSVIFSDNSESDRLNHTAYTQVALFVIEYGLAQLWLSWDIRPT
AVVGHSVGEYVAACIAGIFCLEDALKLIVQRASLMQALPQGGGMAAVFATVEQVRPLIAD
YLQQLSIAAINGEQSIVLSGELEILNSVLQKLESQGIETRKLQVSHAFHSPLMQPMLAKF
EQVTATVKYQQPKLDIVSNVTGKIVRQQEMSNAAYWVEHIRASVQFAASMLALYQAGYEV
FVEVGSHPTLLGMARRECPEVLEEKGLWLASLRKSRGDWQQLLDSVAQLYVAGVEIDWRG
FESDYARNKVILPNYPWQRQRYWLPTATTVPSPSSQSSLSAELQDWLYEVQWQPQTSSDK
TLAIAPAHWLILSDRTGVADNLAQLLAEQGHTYTLVFSGDCTHFEQLLDGIPTQLPLQIL
HLWSLDNTKEADLMLTNIQNHVSAVLHLIQALASRQESISARLWLVTEGTQVIGEHSGEI
AIAAAPLWGLGGAIAMEYPEIWGGLMDLDPSSSPADTAALLLAKLPTMILGDRIAWRHQQ
WHTARLVRSQISPVAAKSLKFTPEVTYLIAGGLGALGLQIARWCVEQGARYLVLLGRSSP
SESAQATIRELEQTGTQITVVQADIAQAEQLQPALTALLTNHPPLRGIIHAAGVLDDGML
LQQNWERFAKVMAPKIQGAWNLHTLTLDQPLDFFVLFSSTACILGAPGQSNYAAANAFLD
ALAHYRQKQGLGATSINWGPWAEVGMAASFGQRLAAEGIDLIPPNQALQLLKHFLQQRVC
QVTVLPINWTQFLQRFPTGQQPAYFRELFSDGQQQENQPSELQQRLQATPVNEWKSLLVA
HISDELTSILGLISSQTIDPLQGFATMGMDSLTSVEFRNRLQKSLGKSLPSTLTFNYPNI
DTLASYFVNTLDNQNMPPETKPTLVNPSQSMTVTQIKQLSEEQVESMIDEELASLIEFSH
>B2J015|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MEPVAIIGIGCRFPGANNPDAFWHLLRNGIDAISEVPVERWDIEKFYHPQPGTPGKMNTR
YGGFIEQVDRFDPDLFGISPREAKAMDPQQRLVLEVAWEALENAAIVPAEISGTQTGVVV
GIGNYDYGILSSKDLDRISAYDGTGNTISIAATRLSYLLNLKGPSFTIETACSSSLVALH
LACQSLRNQETDLFVVGAVSLMLSPQQTITYSNAHMMAEDGRCKTFDAKADGYVRGEGCG
VILLKRLADAMRDGDNIQAIIRGSAVNQDGLSNGMTAPNSVAQQAVIRQALQNASVEPAQ
ISYIEAHGTGTSLGDPIEIRALKTVLMQGRSSEQPCWIGSVKTNIGHLEAAAGMAGLLKV
VLALKHQQIPPHLNLQELNPLISFDDIPFAIPCELQPWQVNTEPRFAGISSFGFGGTNAH
VILEEGRGQQRGNQSQRIDILERPLHLLTISAKTPPALSELAQRYANFLDENPELALADI
CYTANRKRSHFEHRLAVVADSTSELRQQLQLFTARTETTTIVTGQVQGNKRRKIAFLFTG
QGSQYTGMGQKLYQTQAKFRQIIEQCDQILQPYLDKPLLEVLYPQPETNSPIDNTAYTQV
ALFALEYALYQLWQSWGIKPDVVMGHSVGEYVAACVAGVFSLEDGLKLIAARGRLMQALP
ENGAMVAVMATAEQLQPLLAAYKEKVAIAAVNGPQSLVISGEKSAISAITSQLETAGIKT
KQLQVSHAFHSPLMQPMLADFLQVANEIKFAPPQMKLISNVTGQLATIEIATAEYWCRHI
LNPVEFAASMATLQQQKVAICVEIGPKPILLGMGRQCNPTVEGLWLPSLRSGQDDWQVML
LSLAQLHCHGVAVDWLLFDADYSRVRLYLPTYPFQRQRFWIESKTDQKTDRLVHSSIVKL
LHQGNIEQLTQQLASQLSADEQTYLPKLLEVLVKQHQMEINSPAILDWFYQIEWQPQPRR
QPETQKNGAPKKVGSWLILGDRTGLGQAIAQLLQNQGHSCVLVYLGDDYQQQGTATWSMN
PARREDFQRLLREALPSGELAWCGVIHLWSLETTQTKDLSLVELVQAQTWGCISVLHLLQ
AIAENPQPINPTFWLVTRGAISVNSSLPAVQQSPVWGLGKVVALEHPELWGGMVDLDPQP
TADEAFTLLTEISDAQKEDHLAFRSGQRYVARLVPMQPTASSKKDFNSNGTYLITGGLGA
LGLQLAQWLVTQGVKSLVLLGRSDASPEAQATITRMQASGIEILVAQADVCNRADMLQVL
ETVAASMPPLKGAIHAAGAVGYDTITAMDLTTWESILRPKVLGGWILHELTQDMQLDLFV
SFSSIASVWGSKGQAHYAAANHFLDTLANYRRSRGLPGLSINWGPWAEVGMAVGEAQQFL
ARMGVEALPPQLALAALGLTLRGDAAQVTIANIDWTVFKGIYEARGQRLLLEKLETHIQE
NTEKALDEKSEILQNLTAATATERQPILIAYLQAEISKVLGAAQLADTHRGFFEMGIDSL
MAVDLKNRLETNLNCSLPGTLLFEVPNIQDLATYLGKEVLHWQDEPQEVATEPNTDLLKI
TQLSQEEVEASIADKLAELESLIG
>S5YSC3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Paracoccus aminophilus JCM 7686|TrEMBL
MNAKITEMDIIRQQMVAIDELKKRLSTQATEAEPLAIVGMACRFGGKVQSLDGYWDFLAS
KGNAVSTVPAARAQAFAPEDVVYTQKASFLDDITSFDAAFFGISAREAASMDPQQRLLLE
VSHEALEDAGHPIDRKRGDRVGVFVGIMASDYGELVAARRPAQSVDPYHASGRGFCFAAG
RISYTFGFRGPSLAIDTACSSSLVALETARKSILSDECDFALVAGVNVILSPAVNAALCK
AQALSPEGVSKAFSADADGYGRGEGCGALVLKRLSDARRDGNRIYALYLGGAVNHDGPSS
GLTVPSGPAQTELLRRAWRTAGVAPEQLDFVETHGTGTKLGDPIEIRALADALGARETSL
PIGSVKANIGHTESASGLASVIKAALMLSRRRWLPQLLTGEKNPLIDWAKTPLDLAADSA
AWATRDAQRVVGVSSFGLSGTNAHVVLGEAIPGEAEAPAPEAALPALLLLSAKTTTALKR
LIAQYRQLAPDWSTEDLAAICRTTRKGRAHHKIRCAVVAETGLGLQAALDGRELGEPGHE
SAIMRWPVGDDGSEQARQSRDLLARLEGTRRAGALFTSLGLQPEQLFAPGYEQVTALAVQ
IVLLETLQALRMDLSKVQGEALGGQLAAWARGEITREALFAQALTDTPPGGAGDWSLIFE
VPATSRRSEPEPPSASLWTDLLALLGQVYETGASLDWAKLDGAPADPKAPGALLGRAPHY
LFDRQRHWLAEVDQPQFPTNGTPVSTVQSSTEKEKPVQETAGQSVGVADSYTRFDESLLR
YGSGRRAPYLHWAPFAETPDFSWLKVFCPEAFDGGLSEAQESHYLNAISQMRAQSLRGID
FSQVERVLDVGCGYGTDVFDLAAAHDHLRLDAYNITLAQVDVVAKEIAARNLGRRVRVFH
RDSAKDPFPDQYQLAFAYQVVHHVEDKAALLANVADHLDDGGLFVLTDIMAEVDERLEHL
DSEARLLPIAHWVTLFAEAGFRVLSVVDASEPIGNFLHDPDFDRNIQTLREHISAEEADF
AVGPHMLGRMLRKRLARYSMLTLQRDRLLTKAALLQINAALLAAPVPYARLSAADLGFQT
SGEARRTQAASGAGAGAEISARRAGDASGDGAAIAAQVEALIREALEMPESARLPKEAEL
MELGVDSFTALLVVQGIKRELGLNYEMSELLGPGTLGDHIDRVVARAQQARESSVRAADA
SQGIDELSDEEVLRLLAEEQALNAALGA
>A0A166FAD2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudovibrio sp. WM33|TrEMBL
MLEIVGLSVRVPGASSKEELWNLLCSKRNSISEIPADRWSHFRYLHPRISEPGKAYTFKA
GVLDNLWDFDPTAFGISPREAEQMDPQQRILLQLTWEAIEDAGISPDTIAGDHVGVYVGA
SALDYANESLFDPNVATGHFMTGNTLSIISNRLSYIFDLKGPSFTVDTACSSSLVALHEA
YRALNSGRIDCAIVAGVNVLASPFPFVGFAQATMLSPDGQCKAFDASGNGYVRSEGGVAL
VIKRKDAPRWKGQRSHADIVAVDVNSDGRTVGMSLPSDVEQANLLDRVYKAHGIDPNQLA
FVEAHGTGTRVGDPAEAGSIGRTIAQKRRAPLPIGSVKTNVGHLEPASGLVGLAKSVLAL
QNNHFPASLHFNEPNPDIDFDALNIHVASEGVELPRSESPRYAGVNSFGFGGTNAHVILK
DPEIKTDNVEQLTQPKTVSSLFLSAPTKEALVELASGYARDGLLTEQSNQKVCAAAFHRK
RIFPEKAVFSGTDVETLKTTLSDFASGQKNANVIYSNKATNPGKCAFAFSGNGAQWAGMG
RDAYAANQAFKIAFEKVDEFFTNLSGWSLKTELFSETLEDDLKKTSIAQPLLFAVQVALC
QALEDYALKPDMVLGHSIGEVAAAHVAGALTLDAAVALVYHRSAEQEVVAGHGTMAALVL
PADEARQLISKSGFGSLEIAAENSPKSVSLSGAKEDMDGFAKFARANHIAFRKVALNYPF
HSQLIEPVEHPFRNAVGTVTAKSAQVPFISTVSGAVSDGKDLNTDYWWRNLRKPVLFSKA
VATALDLGTETIIEIGPKPILQSYLRQVAAEKGSKGSVLSSLSNEQLGGTDPIINLVARA
FVAGINVDTDKLFGKNPDEPVNLLPLPWQNKSFRFENSGEANMGIFRGGDHPLLGWRPNA
TYNVWTTHLDRFTVPFLEDHVINGQMIFPGAGYVEMALAAGSALYESDAVELRSMDILQA
LVLSDEYLTEVQTEISEETGTVRISSRMRLSGDDWTLHAVGRVAKLETPAPNIQLNFEAA
QLINTGEDIYAAALTYGLEFGPRFQRTQNVSQVDAGTFIVHLSALEDDEQVSSFGIHPAE
LDGCFHGLLSLFRETTSQNSRPKAYVPIFFDKVRQYQTGASPAYVRIQVKRASELSILAD
FQIFDEDDNVIIAISGGRFRATELGRKDNPSDLIYRVEAELQRNPATTVAKLNHSFPAIE
DYVAEKFRTVEDEAEREAYLLLNAAAQRTAFDIISKFADGEQTVSVEDLPNNHRRYFVTL
LTILQEAGAATECGVNRLELNSDFELPDFDLLVESVLEESPQDIAAATILATTRKFVLDS
LDLDSFEGNDFEHSSAMLEQYWYSSPEAQTRSQTISEWLRTALATWDTDTPLHVLDLSGS
GLNLAKDIQQILPSQVTKVSIADSNHKSAARLSASVLDEPNIAVFDTSNLDSNHTWDAAL
EQGPFDVIVSSGLLHEACQSETNLFEKLGQSLTEGGQFLAIEPLSDVFHDVAFGLSEDWF
AGSISDEYPVGPLKTSNDWLDQFTSTSFNAPIAIEALKEGASIVLLNATAKPVDVSQQLD
PTADLPESKAMIILAGNSKLEQEIAKAIQSDERLAACNIKLLDADSGQFDLNEANGWKSA
LAGSAFLDAELKTIIHLYGLTEAGDAPVDQVMKRCATCVGLVKAYPGLAGQLALVAPGGS
GHNAEQEAPAQSAAWTFARVLGNEAPELTPLTLDVCIDKGAQGVASDILEAVFYQNMENE
LHQPQKSRVVSRVKSGFGQSTWKPAENVELNFSEAGSLNHLNWRGQQRIEPSEDHVEIKV
AATGLNFRDVMWTLGMLPEEALEDGYGGPNLGLEISGTVTRVGKNASDLAVGDKVVAFTS
GGYSSYVTCPKFAVAKLDQSQDLVSAATYPVAFLTAYYSLIHLGELKEDQWVLIHGGAGG
VGLAALQIAKHIGAKVIATAGSEEKREILRLLGADHILDSRSLQFPDKVMELTDGKGVHS
VLNSLAGEAMEASINIVRPFGRFLELGKRDYYANTKIGLRPFRRNVSYFGIDLDQILLHD
SDLARKLIEDVFELIKDGTFTPLPHRVFEGRNVQDAFRLMQRSGHIGKILITPPKPEEVK
VPQERTSLKFAQDGHHVVIGGLGGFGLEICRWLADNGARRITLTSRSAKVSEQHEKLFEA
LAEKGVTVSAVSCDVTDRKAVHGLLSELRQSAPLKSIIHAAMVLDDGIIQQLDEKRFRKV
LEPKIQGASLLDELTRQDELDQFILFSSATTLIGNPGQSHYVAANGYLEGLARARRKAGK
PAIAVGWGAIGDVGFLARNAEVSDKLSRHLGEATIKAREGLDILKLAMEQDDGSAPGAVV
HIGRFAWAAAHQSLSLLSKPLFREIIGRSDTDGDSDGATDILSLIEGKSDTEAKEIVAHI
LAGEIGRILRLPAEDISHQRPLAEFGMDSLMGLELRMGIQKRFNLEIPLVSISGGTCLDD
FAAQILQKLRKREGGEASAEDGSHNVLASQHLSDDLDDAQKSTVREILDTHQDKTARLLN
>A0A4P6Q7K9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomonospora litoralis|TrEMBL
MGHSYPADSPSAAVDAQAVAVIGMACRFPGAADPGRFGTLLRTGGSAITDPPPERAAASP
RAGGAPLPGGFVEADAFDPEPFGIAPREAAAMDPRQRMMLELAWEAAEDAQIPVGDLFGT
RTGVFVGAMSDDFAARWHRRGPRAATAHTLTGHSRAVIANRVSYALGLRGPSLALDTGQS
SSLVGVQLAMESLRRGESELALAGGVHLNLAADSAAGEERLGALSPNGRCHVFDARANGF
VRGEGGGAVLLKPLAAARADGDRIHAVLLGGAVNNDGATGGLTVPGAQGQEDVLRRAYRD
AGVDPSAVGYVELHGTGTPAGDPVEAAALGAVLGAARAAGDPLPVGSVKTNIGHLGAAAG
IAGLIKAALGLRDAELVPSLNFARPNPAIALDDLRLRVQREHADWPEAAGRPVAGVSSFG
IGGANCHLVLAAAEPARRSGRATTGAGGAHAPGHDPMPLPFVLSAAGGTALRAQAERLRS
HVADTPDAEPADLAAALALTRSALDRRAAVVAADRAELADGLAALARGSTAGGVWRGTPR
GGGAAMLFGGAAAPYPGMGRELHARHPAFAAALDEVCAGFDPLLDRPLREVLWAPPGTER
AALLNSSGWAQPAVFAVGTALYRLLASWGLRPAFVAGHSFSGEAAAAHAAGMLPLSDACA
LVAAASRELDANSTATVRSGVAADTATALLEAEGLGDRVAVAALDRPRETVLSGDLRSTE
RAAQLLESRGFTTASPAPGAVLPAPGSRRAAEALRAAGRALRVRPACGPVLVSAVTGGVA
GAEELADPEYWARQAREPVRFADGVAALHECGVRVYCELGPGAALAEAARDTVAALPAER
RRNGRGAAFLAGLRAGGEERAAAEYVAGLHVNGVDPDWQAVLGAPARRVELPTYAFRHRA
FGLGPEEPDADAAAAAGEQDAAAHAVDPAGTGADPQCAPAGDAEGMTRLVRVHTAAVLGH
DSPADVDPAARFHDLGLDSMLAVALRNRLAGATGRDLPVTLVFDAPTPEELADRLARERP
SARPRPAPPVAAPSAGAAGEGIAVVGIGCRLPGGADTPEKLWDMVSRGADATSDFPDNRG
WDLDALYDPEPGTFGRSYVRRGGFVHDADAFDAGFFGISPREALAMDPQQRLLLETAWQA
LERARIRPADLRGSRVGVFVGAMVQEYGPRLHEPAPGSEGHRLTGSLASVASGRIAYTFG
FEGPAVTVDTACSSSLVALHQAMQALRRGECDTALVGGVTVMAAPGVFTEFSAQRGLAPD
GRCKPYSAAADGTGWSEGAGLVVLERLADAAAADRTVWGVLRGSAVNQDGASNGLSAPSS
GAQERVLRAALADAGIGPEAVGVVEGHGTGTRLGDPIEAQAVGAVYGAAGSGALLGSVKA
AIGHTQAAAGVAGLISLVGMLGRGAVPAMPGEWGGPSDLVDWSGLGIEPAMGRIRLWPGE
AGAKRIGAVSSFGISGTNAHVLVEEPPRELAYDFAACAPAAPADARAVSPEPAAGRERGA
HAAARLQTDLVAWPVTAAAPEALGPQAARLRGVADRAFAPAPADVARTLSRDRTRFAHRA
VVLAADRSGFGEGLAALEKGASSTERALVVRGTAERPGAPVFVFGGQGAGWPGMGARLMA
SSPVFRARIAECEQALAPHVDYSLSAVLCRLPAAPSLDRVDVAQPALWAVMVALAGLWRS
AGVEPAAVVGHSQGEVAAACVCGALSLEDAAAVVALRSRAVRELVGPGAMGVLGESAERA
ARRAQVRAGAAHVAAVNGPASTVVAGDAAAVADLLGAAEAEGVRVRRIDVDYASHTPHVE
AARDRIRTDLAGIAPRSASVPFHSAVTGAELDGGALDAGYWYANLREPVRFHRAVETLIG
AGHALFLEVGPHPVLTPAVEDVLAESGAEGAGLTTLRRDDGGPRRLLTSFAAAFVRGVPV
DFGALLPGTRGADLPAYAFDRTRYWLKPRRPAAPASLGQADTGHALLGAAVDLADGTAVC
TGRMSTGDQPWSADHAVGGRVLLPAAAMADLAVAAGDRLGCPRLEELVLEEPLVLDAEPA
GSASAVQVVLGPADEHGRRGVGVHSRPEGTDQGWRRHASGTLVGDADADADADADAGAGR
GAAPSCPAPWPPPGAQALDVERVYADLAERGYAYGPAFRGLRALWRHGDELLAEVALDGE
HTHAASGFGLHPALLDAALHALVAAAPADGPPLVPHTVTGFGIAAVGATALRARITPDAT
GAAVSASVALYDPRGAPVAAIDRLTLRPLPKTSSAESARLYALDWAPVEDPPPRTDQTRP
GWAFLGSAADLADPAAGDTAHADLAGLRSAVDGGAPPPGVVVADCPAAAAHRGAARAAHR
TLALAREWVGDDRFAHAVLVLRTSAAVAATPADRLAGLGQSTVWGLVRSAQTEHPGRFVL
VDDDTARHPAAAMHRVVATGQPQAALRAGRIHVPRLAPAEPAAPPPQEGPWRLEAARPGS
LDTVGPRPVPPVAAPLGPGRVRIDVRAAGVNFRDVVVALGLLPGENDIGSEGAGVVTEVG
PGVDDLAVGDRVLGVFDAAFAPQAVAERTHVVPVPAGWSFERAAAVPVAYLTAYYALVDL
ARVRPGEAVLVHAAAGGVGHAAVALARHLGAEVFATASPAKWPLLRAMGLDDDHIASSRD
HAFAERFAGAAQGRGGLDAVVNALAGDYVDTSLGLLAPGGRFVEMGKTDLRDPARVAAEH
PGRAYLPFNLPDVPGDRIRGMLGEVVPLLARGRLGPEPPLLRRPLHDAPAALRALQQGAT
VGKTVLAAPRTLEAGGTVLITGGTGTLGAAVARHLVTAHGVGRLLLASRRGPMAPDAMEL
MAELTGLGAEVEVRACDLADRSAVAELLESVPPDRPLTAVVHAAGVLDDATLQTLTPEQL
DRVLAPKVDGAWHLHELTAGDDLAAFVLFSSAAGVVAGAGQAGYAAANAFLDGLAHYRGA
RGLVAASLSWGLWAHSSGMTGHLGAAELARMRRSGVEPMSTADGLALFDAALALDRPHLV
PARLSDRGPAGPRQGTGARRPAAAAPDEPAASRSAAAPAGPSADERRSALVELVREHAAA
VMGHTSSTALRPDRQLTEAGIDSLTAVELRNRLNTATGLRLSATVLFDHPTPQALAGHLA
ARLGIDDEAGGRGPAGASDGDDRERDELMDALRSLPLDRLRASGLARSLLDLARTGTDTP
AASRTPVRPDGTEAPDAPERTGGGIESLSVDDLVGLALAEDDTR
>A0A5C6B3Q4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Stieleria varia|TrEMBL
MNFIASHSSVPDEQLPSPACFGERESIDEPIAIIGIGCRLPGNIKSPNDYWRILCDGVDT
IEEVPSTRWDQFKFYDSELGQQGKIITKWGGFVKDIDKFDPGFFGISPREAACMDPQQRL
VLESAWEALEDAGQRVELLAGTNVGVFVGVSTFDYGLMQNTFNDVSGAGPYTNTGQALSI
CANRLSFVMNWKGPSFAVDTACSSSLLACHMAVNSIRSGESSMAMVSGVNFICAPSTYVG
FTAMGMLSPDGRCKAFDASANGFVRAEGGCSVLLKPLKQALVDCDRIYALVAGSACNQDG
HTPGLTMPSEASQQALVLEACRRSRIEPSQIRYVEAHGTGTPIGDPIEANALGSILGRGR
NVDNPCLIGSVKTNIGHLEAGSGIAGLIKAALVLKHRQVPPNVHFNDPNPEIDFTALRLK
VPTEMTELPVGNGPAYAGINSFGFGGTNVHVVLREYQPLPVRQSGNANHRRVGFMPISAK
CPESLRAMAKTYADAMQDGGMWSDASLSDILYTTSQRRSHHDFRTCVVARDKNELKLRLL
ELAENDSDPSMKSDHPQRGGARPIAFVFSGQGPQWWAMGRELLRSEPVFSDIVARCDSLI
QELGVWSLLTELSRDEATTRINDTTYAQPAIFAIQVGLVELWKSWGIKPHVVVGHSVGEV
AAAYAAGILNLKDAVKVIFFRGQTMGVVRDAGAMLAVSMTPDEATKYIRPWKHRIDLAAV
NGPSTVTLSGDTSMIAQMEHDLESMRIFTRRLKVNYAFHSQQMDPVRKELVNSLADIRPQ
ASSIPMVSTVTGQTIDGHELGADYWWKNVRQKVLFLDAMNQMPESDQAIFLEISPHPVLA
GAIGECFAAKGQQADVVTSLRRGQPERAELLKSLGKLYGLHCSVQWPVLAPTATFLPLPA
YPWHKQSYWSESEDSRVSRLPCEGHPILGARVPGSRMVYQGFIDTRIQPFAVDHQIQGHV
LMPGTGFLEMGMALGREVHGEGNFVITDVELLKAAFMPVKETLMTHTILDIRTGRYSIET
QPLGQPHRPWTVHCTGYLRERAPVPPSIKPELSDVRRRCIESLPAKVFYDFFRRCGFPFG
PSFRGLTQIRLGIGEMLGCVDVPPECEADFDDYLFHPAVLDACLQGNFGCFMTHNRTSNN
LGDLEERIRKAEIFMPSGYDEVRLYKRPNQRMWTYVRMLERFKDQSSSDVFIFDDDGELI
AEIRGFKETLVGTVDGNAETTSGLLYEYEWKLQPHPNTDVKRHRLPLLADCVDAFSVTET
QSWDVLVAAVDSESELQSQLHPICGAVVAGAMRDLGLRGKPGTVVSFDAVSSLLNIPANR
CGLMRRLLDILVQDRMVERCDSGFELMEGFSKASQSNDRPWLAALRRLFHSHPVAYPQLM
LLARCADRLPAILRGELDPSTLLAPDDSDEVREQYWVSSPSAHVVFRLSAQFIASLFHDM
NPGRKARILDLKGGSDRLAAEILAALPAGLVEYVSADVSEHGFAQAEEDQENFQYEVIVA
DDVLCPGDDLEDAIRRLHNRLVPGGVLLLITSDKGDRLYDLTLGLRDAERDLTHQSIANW
YDVLFSAGFDDARVLHPDLQSTDVTRSVIVAQRSFGDAAAQADSTTEHQELAIADISDTQ
AIDGGDWLIFADTSNVAVELAELARQQGQSAIFVHAAESFAEISHDHFSIDPTSLEDYQR
LLKSISERALTQVVYLWSHNVPELSVDPASLQAVQTFNVLAPILICQAWTLIHGALPIRY
WLASRCAQSVGNLSLTHAVGQTPLWGTGRVVMNEFPHLHCRLVDLGVATENELRALVNEI
LGESGEDEVALRDEARFVHRLVASSLSKYSDRGDEPGQPYRLHLSDYGALDGMRLRPAEL
PRQLGSPTLVEVEVHAAALNFSDVMKALGLYPGLQEGFVPVGIECAGVVTKVGDEVTDFQ
IGDEVVCITPMAISSHTYTDHRLVAHKPKQLTMFEAATLPIAFLTARYALHYVGRMESGE
KVLVNAATGGVGLAAIQLAQTAGAELYATAGTISKRELLKFLGVPHVMHSRTLAFADEIR
EQTADRGVDLILNSLSGEAISKGMSILADYGRFLEIGKRDIYANTALGMRAFRKNVTFAA
IDLDRALREKPDLCSQIFREIVADAETGKIMPLPHRVFPATELVDAFRYMSKAKHIGKVV
VDMKGQPVRPVRDPTETTVRFRADATYLLTGGLGGLGSHLAQWMADQGARCLVLASRSGV
STVEGQQLVRKLEQRGVRIVIEQVDVSQADQVAGLIRRIKSNLPPLRGIMHAAVVLDDGL
ILQLDRDRIERVCAPKLNGAWHLHNATQDHVLDFFVCHSSTSSTLGNAGQANYSAANAFL
DGLAEYRKSIGQPALTVNWGYLGDLGVAAGNEKLAERFAQQGVRPIAPSEGLPILGGLMA
FPINQMSVMRVDWTRLRQFASTMARSLRFSQLMHTSAEGEEAKSHSGSDIRLLVLATAPE
ERTDIMLSIVQKKVARVLGTRPEKIELDRSLMDLGLDSLMGFELRNWIEGELRVNVPVVE
LMQGPTVQKLTSLLLAQLEKTETPVNEAVESAERSDVLANHVARLSTHPQQEAAIAGLLA
MADEFKDELQGCDSIDLVSEAQLPDDVLGDDFAERLRAQMHQRQPIQCILVTGGTGFLGA
YLLHYLLESNPQLQIHCLVRADSAAAAIQRLQENQEKYCLWNPGFAERIHVVLGDVTLPR
LGIDQMTYDRLADEVELVLHNAAGISFLQNYEQLKPVNVAGTLEVLRFASHRRIKSYHHV
STLFVFSILDHLELNTVSESDDPSRHEFLFGGYLQTKWVADHLVQEARRRGMPVTIYRPG
IITGDSRTGICSDDVISRMLASAIQLGCCPADETRITFTPVDYVGKAIATLLMSRENSSR
NYHLVNRDAIQWQTVVRWLAELGYDVQMQPYDKWLEQLRQSTRDDESTMLSGLLPLIPEV
RLTGPTADLIKMNFDCGQLDEMLADTGVLCPTVSLDLISTYVNHFVRSGIISPGQTSIDG
ESDASQQAAASMLIDEN
>A0A2S9YVF0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Enhygromyxa salina|TrEMBL
MSQPDPKELRATLVRAMREIERLRKQVAALESAGVPIAIVGVGLRLPGGICDLTGLWRAL
EAQLDAIGPIPADRWKLDDFYDPDTEAAGKSYAREGGFVTNIDRFDPGFFGISPREAKSI
DPQHRLLLETAWEALEHAGIVPGSLAGTRTGVFVGIGASDYGSLMRDAVDGDGYAIMGSH
VSFAPGRIAFHLGLQGPSIALDTACSSSLVALHLACASLRARESTIALACGAAAMTDPHT
FVQLSRTRALAPDGRSKAFSDRADGYGRGEGAIVLVLERLSDAVASGREVLAVIRGSAVN
HDGASSGLTAPNGLAQQAVIRAALSDANLEPNEIDYVECHGTGTILGDPIEVGALAAVHA
KGRTNDRPLLLGTVKSNLGHLEAASGLAGVAKLIACLRHAKLPASLHALPLNRHIEWESL
PLAVVTESVSWSAQAQAPRRAAVSSFGLSGTNAHVILEGPPPPPAPRARAHAVASPVPLL
LSARSQPALRHQAQQLLAHLRAERASAALGDVAYSLATTRSHLEHRVAFVSADLEGALAT
LESIAADGGSRAPIGDRVRARPLLAVMFTGQGSQLHGMGGALIDAYPVFRDAFEACAKLF
DAQLEHDLRAVVRGDEPHAELLDQTAYTQPALFALEVALFRLFESWGLTPDLVLGHSIGE
LAAAHVAGVVSLEHACALVAARGRLMQALPSGGVMISIEASEAEVREQLGRRPGAVDIAG
INGPRSTVIAGDDAAARAVAAEFEQLGRAVKHLTVSHAFHSQHMDAMLAPLEAVAAGLEL
RPPTLELVSNVTGRLATPAQLSSAKYWADHARREVRFFDAIRTLETLGTTVVLELGPRGV
LTSMAAGCLAPDAAKPMTLIASLRGDRPAIEALASSVAELHCHGIALNWSAYYEGRGCRR
VPLPTYAFARERHWLDARPPRAGVGSSGRHPLSGVRVELPDDGAIHNVELGPAVQRYLAD
HRVFETIVVPGAFYLAIMLAIGESCWPGRAIELRDVEFVRALGFEGPDDRVSLHVRLTPV
ERDQLAASLHSRDSEGVWTTHANAILRAIEPPQLEPSLDLDSLEWSADQADFAQMLQTMQ
IDWGPSWWWLTQTSATTDATVVGRLVAPDQAQIQDAPIPGGLIDNAFALVFWTPGFVYDT
TPRLPFAVRRMVWSGAPTQPHYAALTAVENALEQTTSNIGLFDDRGRPLAVIEGFVTRSA
PPERFLARRPVRDLYTVDHERVAAPGPRAATWTRLGAPIDGLPGPAAQFDDVEALQLARA
EAGLELGLTLSLCDPNATALELTLTTLAMLRTWLRSTQLAGHRLVVITRQAIAAKPGDPV
EHPAQASVWGLLRTAQTEHPEFSLTVVDVDEDPRSTAALLSVPDRPQLLIRGGEYLEPKL
AAASLGREPLANPLSALAGTVLITGVTGALGSIVARHLVHEHGVRHLLGLSRAGARSPGA
TELCTELALAGAELRILACDVGDREALEHALATVAPAQPLVAVMHIAGALDDAVIEDLRV
EQVERVFAAKVDGARHLDELTRARPLQAFVLFSSYSGIIGTAGQANYAAANTYLDSLAAQ
RRGLGLPATSLAWGPWAEGGMAARLGERDRGRMRRQGVEPFSSADALALLDAAVRHDASV
CVPVRLDLAALAAADAEPPSILRGLAPRPPTSSSPAPSLPASLAQLDATRRDAATLALVL
DATVAVLGLAGASELDPEQPLSELGLDSLMAIELRNRLQRATQLRLPSTLLFDHPTPASL
RDRLLTELSEVAATVPAAAARSSTQRPHTDDDDAIAIVGMACRFPGGVQDPEQLWALLQD
GRNATGPMPSNRGWDLDALHDPDPRAPGKSVTQRGGFLHDAADFDPLFFGISPREAEAID
PQQRLLLETSWEAMEDAGIRPAKLRGSNTGVFVGIMYNDYGGRFINDPAALTGHVALGSA
ASVASGRLAYVFGLEGPALAVDTACSSSLVSTHLAARALRERECDLALASGVAVMATPGS
FIEFSRQGALARDGRCKAFGAAADGVGWAEGAGVLILERLADARANGHTVHAIIRGSAIN
QDGRSQGLTAPNGPAQQRVIEAALAAAQLSPLDVDAIEAHGTGTVLGDPIEAQALQAVYG
RGRPSDAPLWLGSIKSNLGHTQAAAGIAGIIKIVLAMRHQQLPRTLFAAPASPHVDWSSS
LALLHEPRPWTREGRPRRAAVSSFGISGTNAHVILEDVDAPVADEAPSSAPSVVVISGKT
DRALRAQARSLRRWLERHEAASLTDMASGLAIARTQFAHRAAFVATTRERALSELERLGD
DRPDHTTALGVVAHRPTLAFMFTGQGAQWLGMGRELFERQPVYRAAFSQVAAHLDPQLER
PLGSIVFAEPGSATAAYLDQTRFTQPALFAVEVALYRLLESWGITPQLVIGHSIGELAAA
HVAGILSLAHACQLVAARGRSMQALPTGGAMVAIAASESEVQAEIDRQLATVDIAGINGP
ASTVVSGPAQATSAIAEHFEALGHRVRRLEVSHAFHSRLMDPMLDEFRRVAESIEYAAPQ
LAVISSLTGALADPDQLRDPAYWVRQVRDPVRFHDGVLALAHEGANVLLEIGPHAVLSAM
ARDCLAADSPVSVTASLRRDRSDAKCLAETLAQLHCRGVEVDWLPYVGRGQARLAAPLPT
YAFQRSRYWMSPPPPPKPEPAAGSLERSLWSEIERGDVGRLAKLAGVEPAVIDDSWLAAM
HRLRAHAERRATLDSWRYVERWIPARDHVGPNAPAACVFIIPTGLELELPVGARTLTLER
TSSREQLATQLRELAAQRPIDNWVSILALDSTPSDHHCALTLTLMHALCDLGDAPETASA
KLCVITRGAVSTRPTDEPVDPTQSMIWGLSRSFALEYPGRWGGLVDLPLEPSHEDARWID
AGLALAGEDQVAVRDGALIVRRLARVTANSGAPELELPRVALVTGGTGALGAQTARWLAH
AGTPHLILTSRSGDRAAGATQLRSELEALGARVTIARCDVANADALAQLLAQLASDGASP
DAIFHVAGISGEPGPLAELDHAAFAEVAAGKVVGARNLHEQTLALPIRTFVLFGSIAGVW
GAAQQAAYSAANAYLEGLARHRTASGLAATCVGWGSWAGGGMAEGSAGEALDRLGVRAMD
PEVALAGLALSLAEGHSAVVIADIDWSVLAPLFAMHGPRPLFDAIDEARRATMKLPSAQD
LRRALEQLSPAQLHAAGLLDQLMEIAGPGLELASASTASSPPPRLTHAQIIPAIIDAARQ
VLRVPAEVLDPGTGLTALGLDSLMALELRTLLDSKGISIPIAELLRGRSVAELAAIVTDA
SPTSPDVTPAPPVGAWISVDTPRPDAQLRLVCFPYAAGGPAVFAEWPALLGEDVEVCVAH
LPGRGSRLDEPPLRSIDAFAQPLVEAMVPLCDKPLALFGHCMGSVLMFEVAARLEREHGA
SFVRVFASGSAPPGSYQSPLLHLLDEAQLMEALGVIGFTNASALLEDRELRTLLLPMLRG
DFEAVADYSTKYEALTPISSPITVIAALRDAFVAPRFIPRWARYTTDTTTLNLIDENHYF
VESDRAAVVELVQAELFGGQRSSARIRMIPTDEWASSIRDRPTPSPAASPVVWRRPPSEN
TTATLVLLPDIWGTSFPLDNPDAVDPRWSLCEVRYPDGGDSAEVFLDQLLTWFGDAVGHP
AVLLGHGFGGICAAELAARFGDRVDALYIANAIPPGDYGLPFADLLSDDALLRLLALAGH
PSSTPAALPRIRAGVQLGSSYPVERRVLVACPITVLRGRRSILFSFHTAAHWSHATTGVV
RFVDHDGDQFTALDAELLPRLRI
>A0A2S9XYH1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Enhygromyxa salina|TrEMBL
MTDPAQAKLRKTLSRALTEVKRLRAKLAELEGPSTEPIAIVGIGLRLPGGVVDLASLWSL
LERGQDAVAPIPATRWDAEACYDPSPDAPGKSYVREAALLDHVDLFDPAFFNITPREAAS
IDPQHRLLLEGAWEALEHAGIVPATRVDSQTGVFVGIGPSDYARLIDDAGDNPYAVMGTH
SSFAAGRVAFALGLQGPAMTVDTACSSSLVALHLASSSLRARECELALAAGVQVLASPEP
FVQLSRTRALAPDGRCKTFSADADGYGRGEGVVVLALERLADARAHGREPLALVRGTAVN
HDGRSSGITAPNGSSQQKVLRAALTDAGLEAHEVDMVECHGTGTALGDPIEVQALAAVYG
AKRRPERKLLLGAIKTNIAHLESAAGLAGVAKVIAALDHDTLPATLHCASPNPHLDWGAL
PVEIIRDARPWPRGEGPRRAGVSGFGLSGTNAHVILEDAPSPAPAKPPIASLEYVPLLLS
GRTEAALRDQAARLLARVEDPRGRPSTLELGAALATTRTHFEHRAVAISPASASAKAALA
ALELGSSSPAVTPKLALLFTGQGSQRPQMGRELYERFAVFRASVDELCSKLDRPPGAGSA
RRRRPLLEVMHAAAGSEAAALLDRTEFTQPALFTLEVALYRLFESWGLRPKLLLGHSVGE
IAAAHVAGVLDVDDACALVTARAELMAALPPGGAMWSIQASEAEVDAALAEQPGALDIAG
LNGPMSTVISGDEAPARALAEQFEARGRKVKQLAVSHAFHSRRMEPMLAEFEARIAALRF
KHARIPIASNLSGAIAGPEIATPAYWVRHVRQAVRFVDGVRALETHGATATFELGPQGVL
SAIAAGCLSDQAQARRLPLIPSLSKSAPEPLALMTALARLHVHGVSLDWSAVFELQRPPR
VALPTYPFQRERMWLEPRPRPATGALAGRYPLSGHRTELPHGGALHTLEIGPAIQRYLGD
HIVYDTIVVPGAFYVAVLLAVAESTWPDRAVELRELEFIRALTFKAPADHVTLRVQLDPL
GDDLSQYAASLSTRSEGEWTTHASSILATPSDDPPAPEPLDLRGASWVDDSERLDRRLRD
MHIDWGPKWWWLRQTAALGPDTVLGRFDAQAGVPGDDGPVPGGLIDSSFALATWTAGYEQ
GSTPRLPFAARRVVWLGQRRPPQRARYQARSTTQTSSTADITYYDADGRALAWIEGFSTR
PAPIERFLPPRASRDLYIVSWVALDEASRPVAPVAPVARLGGDPLGLAELYAFDAVHPDL
ASVIAGQSQTVVVSCGPGESPLATASATLELVQAWLSASALSDRRLVLVTRDAVAVDPGP
SALDLAASVIWGLVRSVMAEHPERDIRLIDIDDDQPAASAPFARALGCEESQLAIRRQSV
LASRLAPAPSASERPPPAFDANATVVVTGATGGLGAALTRHLVARHGVRRLLLISRRGPD
SPGAEELVADLQAAGAEVELLACDVGDRAQLADALASIDAAHPLTGVFHTAGVVDDATVA
GLDEARLARVFAPKVRGSRNLHELTASHKLVCFVVFSSLAGLLGSAGQANYAAANAYIDA
LCAHRRARGLPATSLAWGPWAEGGMAARLSEVDRARMARQGFLALSFEQGARLLDAALER
SAALQVPVRLDTRALGASSDELSPLLRDLVPRASPRRRSEDSSLARRLVGLGEAEQRSEL
LDLVTRETATIFGLSDPSSLGPELPLQELGLDSLMAVELRNQLQAATKLRLPSTLLFDYP
TLTALADMLRERLLALATETEHESPPAATPRPPRVPHERDPIAIVAMACRLPGGVHSPEQ
LWDLLDAGLDASTELPSDRGWPKDLYNPDPAKPGKSVTARGGFLHDAAAFDPAFFGISGR
EVAAIDPQQRLLLETSWEALERAGIPPDSLRGSPTGVFVGVMYSDYGGRLFASPEALEGY
VGIGSAPSVASGRISYTFGFEGPAVSVDTACSSSLVALHLAAQALRNHECDLALAGGATV
MATPSMFVEFSRQRALAPDGRCKSFASDADGVAWAEGAGMLVLERLSDARRHGHPVLALV
RGSTINQDGRSQGLTAPNGPSQQRVIRAALAAASLSPADVDLIEAHGTGTKLGDPIEAQA
LAAVYGPHHSSDAPLLLGSIKSNIGHTQAAAGVAGIIKVVLALERQHIPRTIHVTEPTPH
VDWSSGALRLLTEPQAWPRGQRQRRAAVSSFGISGTNAHVLVEEAPVEDIAEGPRERDEE
HAQSWRCLLLSSPSASALPGLAARLRDHLRANPQLRLTDVAYTLAAHRTQFEHRVVLVVD
SLAAAVTTLDALARGQTPPEVSVGRARAAPRSAFLFTGQGAQRPGMGADLVAAFPAFRAA
FDEICRRFAPHLERSLRAVIFAEPGSDDAALLGETAYTQPALFALEVALFRLLESWGLAP
DLVLGHSIGELAAAHVAGVMSLADACELVAERGRLMQSMREDGVMISIQASEDELRPLVD
ADPGVDIAGLNGPRSTVLSGDEQAARSVAARFEARGRKTRQLAVSHAFHSHHMEPMLDEL
RAVAETSTFAAPRTSLVSNVTGRLADPDLLRSPDYWARQVRAAVRFADGVRELEREGVTL
AVELGPHGVLTASAATCLEHPDQVRLVSTLRRDRADLESLHVALAQLHCAGAGLSWADYY
RPLDARLVSLPTYAFERARYWLEVPTKAPAQDPHAAAFWSAVEARDDAQLGALLDLDDQS
QTALTSVLPALRAWRGTSRERETLDSWRYRETWVPLAVDTGPASQAPWLVIATTDAAGSV
AERLGAQLPTTLVIADPEAGREQLARRLRRAAGDGPLAGVIADLGSSEHHPRHRGLPLGL
ALALTLAQALADAEIDAKLWLLTRSAVSTGPDDHLEHPLLAMIWGLGRVLSLDQPQRWGG
LVDLPCEVPDALVSTLARALLRGGHEDQLAIRPRGLLARRLERAPAEALGPRFRARGTAL
ITGGTGALGAHTARWLTKRGAAHLVLTSRRGEAAPGARSLRAELESLGARVSIERCDSAD
PRAIAALVAKLSELDGSDEELRIIAHAAGVSGPPTSVDQLSIEGLAEVTAAKVCGAAALH
ELTLTRDLDAFICFASIAGVWGSGQQAPYSAANAYLDALALHRASSGLPATSLAWGPWAG
PGMADEELSELLRSHGLSPMAPAHAIASLELALRSRDPSLVIADLDWSRFAPVYASQRPR
PLLTAIPEARRALAPLPSDAQLRRALERVSLSQLREAGILDAVLDLVNDASPTEAAAPTD
LLTLPISERRAAVREQLRAFAARVLRVSVDEIEHDQGLTALGLDSLMAVELRTQLAAAGI
AIPAADFLRGLSVAELAERFIASSGGPSETGETGRPTSRWINIEHPSSTADLRLVCFPYA
AGGPTVFAQWPQALNPAIEVAVAHLPGRGARLDEPPLHTIAESVGPLVEAILPLADKPLA
FFGHCMGAMVMMAVAERLEHEHGVILERVYASAAAPPSHYQAPLLHLLDDDELMLVLQMI
GFTNSGALIEDDELRELLMPMLRADFEAVAHHSRDYRPRRPLSAPLVVLAGRRDVFVAPR
FVPGWRQFTTAEVRFELLDEHHYFVESERAALLSLISGERGSDGVIRALAAKEWDAALRD
PEPFTRDGWDRRAEWLRVHQPAKSAVGTLVLIPDLLGARFPLHSPTTCGASWRVLELSYP
GLERGDPRSPGPPDQVIARFIELLEGEDDGPLILLGHGFGAVCAAEIAAALGPRVRHLFA
VNGVPPGHYGLPFADLLDDPQLVAFLRLIGHPRPDPSSLAQVRAGIRLGSAYPVESEREL
PCPVTALRAKRDVWLSYHTVDRWADVCQGPVEIISREGRHFDDVDEQLAPQLRALSASLP
DP
>A0A5P9PYH5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Amycolatopsis sp. YIM 10|TrEMBL
MTERASVNEIAIVGLSCRLPQAPDPRRFWALLRDGVDAITTMPGDRWDSDTPVPPGAERG
GFLDRVADFDAAFFGISPREAAIMDPQQRLVLELAWEALEDAGIVPATLRDADAGVFVGS
IGSDYGTLMQRAGLINQHTITGTNRGIIANRVSYALGLRGPSVAVDTAQSSSLVAVHLAC
ESLRNGESSIALAGGVNLNLAPESTLTAARFGGLSPSGRAYTFDARADGYVRGEGGGLVV
LKPLARALADGDPVYAVIRGGAVNNDGATDGLTVPNALAQEALLRKAYSDARVLPSYLEL
HGTGTRVGDPIEARALNAAFGAHRLRVGSAKTNVGHLEGAAGIVGLLKVALSIHHRELPP
SLNFATPNPDIDFEHLAVQQELEEWPGPRVAGVSSFGMGGTNCHLVLTAAPERPHRISST
PGVVPMLLSAKSLAGLRAQADRLASFVTDQHLGDLGFSLARTRAQHEHRAVVLASSLEEL
RDNLATLRPGVAGQAKVAFLFPGQGSQRAGAGRELYERYPVFATAVDEICAHFDYHLDRP
LREIMFSEAEALGQTRYTQPALFTLGVALYRLAESWGLRPDLLLGHSIGELAAAHVAGVL
TLPGACSLVAARGRLMQSVTAHGAMVSFKGTEAEVRALLTDGVDVAAINGPDSVVLSGDH
DTVLELAQTWKAQGRKAKQLRVSHAFHSPHMESILAEFRELASALNFAPTTLPIVSNLTG
ELATTEQLCSPDYWASHIRHAVRFADGVRFLADAGVTNFVELGPDPVLAGMARDTASEIT
MASMLREGRSEERTFLNALASAHNSGARVDWSQAFGEAQRISLPTYAFQRERHWFGETTR
LKADTPSSPWADRLDGLSEAEQEDVLLDLVRTSVAAVLGHSSADAVEIGHTFKELGFDSL
TAVELRDQLSAATGLNLPGALIYHHPTATALARHLRAELLDAPSTTVATVGAVSDEPIAI
VAMGCRFPGGITTPDELWQLVADGVDAITEFPDNRGWDLDGLYDPDPDQPGRSYTRHGGF
LHDADAFDPAFFGINAREAAAMDPQQRLLLETSWEAIERAGIDPASLHGSGTGVFVGAMS
QDYGPRLHEGTEGGGYLLTGNTTSVASGRIAYTFGFGGPAVTVDTACSSSLVALHLAAQA
LRHGECSLALAGGATVMASPGMFVEFSRQRGLSVDGRCKAFAAGADGTGWAEGAGMVLLE
RLSDARRNGHPVLAVIRGSAINQDGASNGLTAPNGPSQERVIRSALAMAGLEPADVDAVE
AHGTGTALGDPIEADALLATYGRDRSEPLLLGSFKSNIGHTQAAAGVGGVVKMVMAMRHG
VLPKTLHVDEPSPHVDWSAGAVELLTSPVEWRRDRPLRAGVSSFGISGTNAHVILEQAPE
ESVVPASDAAPDRTIPWLLSAKTEGALRAQAARLLDHSGGTPAEIGFSLATTRPSLERRA
VVLGDSEDELRANLAALAEGSDSALAIVDSLRTTGRMVFVFPGQGSQWAGMGLDLLDTAP
VFRDQLLACADALAPHTDWSLLDALRGEGLDRVDVVQPVLWAVMVSLAALWRSVGVRPDA
VIGHSQGEIAAAYVAGALSLEDSARIVALRSKAIVALAGTGGMVSVPLPAADTERLLTRW
PGRIHIAAVNGPTSTVVAGEPGALGELLADEQVRARRIPVDYASHTPHVEAIRDELLDVL
AGITPRAADIAFYSTVTGDVIDTAELDTAYWYRNLRQPVLFEQATRALAAAGHRVFVETS
AHPVLTNGLGETLDDAGVVTGTLRRDDGGWDRFLKSAARLHTTGTRIDWGSLFAPGTRTV
ELPTYAFQRQRYWLDVPAPTGDPAASGLDAAEHPLLGAAVTLAEENRLVLTGRLSLRTHP
WLADHAVRGTVMLPGTAFVELAVQAADQAGYTSLRELTLHAPLLLPAEDGVRIQVVADGE
EVRIYSRAGEVWTLHATGALGSEAGELAPLSAEWPPAGASPVDLEDIYDRLAERGYDYGP
SFRGLRSAWRLGTEVYAEVRLPEPDGAADFALHPALLDAALHAVVGLVPLSGGDGEIPLP
FHWDGVRIGAAGAAALRVRVAPHGADRVALALADSSGLPVASVDSLLLRPMSAELLASAS
ATPLESLYEVAWTEVAGATTEPAQVVSFGGGDVHAVTAAALDAIQAHLSEEDSAPLVVVT
KGAVATRPGEDVPDLGAAAVWGLVRSAQTEHPGRFILVDTDGSAPVLVTGEPQSAVRSGR
PLAPRLARTTVKAAAETTPDQVAAVPARTVFHPEGTVLITGGTGVLGALVARHLVHRHGV
RRLVLTSRRGHAPELREELSAAGAEVTIVACDAADREALESVLDGIPELTAVFHTAGVLD
DSVITALDSERLSSVLRPKVDAAWHLHELTRERDLAAFVLFSSVTATIGSPGQANYAAAN
AFLDGLAHHRHAHGLPATSLAWGLWAESSGLTSSMSAGDRARMARTGIAPLPTEQGLALL
DAALADDRPALVPAKLDLSSATLPSLFHGLRRPSRRRVEDQPDTADTWTQRMLALSPAER
GRAVTELVRAQVAVVLGLDANATIEQARAFKELGFDSLTAVELRNRLNTATGLRLPTTMV
FDHPSPAALTEFLRTELDGGTTAEAKPAVGSTPPGTDEPIAIVAMACRYPGGVRTPEDLW
RLVETGTDAIAEFPGDRGWDLEHLFHPDPEHGGTSYAKHGGFLYEAADFDAEFFGISPRE
ATATDPQQRLLLETAWEAFERAGVSPDELRGSDTGVFAGVMYDDYGTRLGTAPDGYEGHL
LTGNTTSVASGRIAYTFGLEGPAVTIDTACSSSLVAMHLASQALRRGECSLALAGGVTVM
ATPNVFVEFSRQRGLSADGRCKPFAAAADGTGWSEGVGLVLLERLSDARRNGRRILGVLR
GSAINQDGASNGLTSPNGPSQQRVIRQALANAGLRPSEVDAVEAHGTGTTLGDPIEAQAL
LATYGQQRETPLHLGSVKSNIGHTQAAAGVAGVIKMVEAMRHGVLPKTLHVDEPSPHVDW
SAGAVELLTSPLEWDRDRPRRAAVSAFGISGTNAHVILEQAPPDDHRPEPAGIVPWAVSA
VSEQALREQARQLRARVADLPEPDLGGIGAALARRAVLPHRAVVLAADREDFLLGLDSIV
AGEPASNAALGSADAPGKKVFVFPGQGSQWAGMALDLLDTAPVFRDQLQSCADALAPHID
WSLLDALRGEGLDRVDVVQPALWAVMISLAALWRSMGVEPDAVAGHSQGEIAAAYVAGAL
SLEDSARVVALRSRAIREIAGLGGMVSVPLAADATEALLMGRDGLGIAAVNGPASTVVSG
DVTALDQLLADCEGSDIRARRIPVDYASHSAHVEAIREQVLADLAPIAPRTSDITFYSTV
TGEPIDTAELDAAYWYRNLRQTVLFEPATRRLAADGYRVFIESSAHPVLTVGLQGTLDAL
ETDALVTGSLRRDEGWARFLDSTARVHVRGTAVRWDFYGVRPAELPTYAFQRQRFWLDAP
ARTGDVTAAGLDTTGHPLLGATMDLADGALVLTGRPNLRALPWLADHRVFDTVLLPGAAF
TELALEAGRLAGCEQLAELTLHAPLVLTEESTRQLRVTVGEPHDDGRRPIEIHSRADREP
WVRHAAGQLGNAADEQAEPAPFVAWPPERAEVIEPSELYEKLALRGYDYGPAFQGVVAAW
RDGDELFAEVRLPEGLPAQAFGLHPALLDAALHTVALAADGAAAGQVMLPFSWSGVSRFT
TGATALRVHVTRRHDTFTLRTATPDGTPVLTVDALVTRPIDASRLRSGAERELYALEWTR
LEPGTEPAPEYEVVDCPPGEHGVPANTHEVVTGLLTKLQEWLAGDNTDHTSKLVVLTRGA
VALPGEPVEDLAGAAVWGLVRSAQTEHPGRFVLADVRDATRDALDTALASGEPQLVVRGD
TAYVPRLAKAQPERPQLGDSVLITGGTGVLGSRLARHLVTTHGVRHLVLTSRRGPDAPGA
AELRSELTALGAEVEIASCDAADREALAALLDGLPGLTAVVHAAGALDDSVITALSSEHL
LTVLPPKVDAAWNLHELTQDRDLSAFILFSSVAGTAGTAGQAGYAAANAFLDALAAHRQD
LGLPGTSLAWGYWAEETGMTGHLTEADRLRLAQSGFAPMDTAEGLALFDSVHHGVRVPAH
LDLAALRARAAGGTLPPLFAGLVRAPARRVTTGLADRLSGADPAEQLKLLTELVRTHAAA
VLGHSGAQQVPAERAFKDLGFDSLTSVELRNRLSDATSTRLPATLVFDHPTPQGVAVFLR
DRLGGTRTTKARAKAATGHNEPIAIVAMACRFPGGVRSPEDLWRLVDEGTDAISEFPDNR
GWELDRLYDPDPDAQGTSYVRHGGFLHDADEFDPEFFGISPREASATDPQQRLLLETAWE
TFERAGIDPGTLRGSDTGVFAGIMYDDYASRLLKSPPKDVEGYLVSGSAGSVASGRVAYT
FGLEGPAVTVDTACSSSLVAVHLAAQALRSGECSLALAGGVTVMATPAVFIEFSRQRGLS
PEGRCKSFAASANGAAWSEGAGLILLERLSDAQRNGHHVLGVIRGSAVNQDGTSNGLTAP
NGPSQERVIRQALANSGLEPSEVDAVEAHGTGTTLGDPIEAQALLATYGQQRENPLHLGS
IKSNIGHTQAAAGIAGIIKMVQAMRHGVLPRTVHVDEPSPHVDWSAGAVELLTEPLGWDR
DRPRRAGVSSFGISGTNAHLILEQAPETNEHPTTEHVGPLPFVLSAKTDAAVREQAARLA
ERAGESTLPDIAYSLLTTRPLLDRGAVVVAADHEELLSGLDKLGATTARDDEGGLAFLFT
GQGAQRPGMGRELHDRFPRFAEALDEICTHLDTELDRPLKTIMFTGEELDRTIHTQPALF
AIEVALYRLYESLGVNPSCVVGHSIGELAAAHVAGVLSLEDACRLVAARGRLMQSLRDDG
GMAAIEADEAEVLASLKGVDGVSIAALNGPSATVISGDRDAVLDIAATWKAQGRRSTRLR
VSHAFHSPHMDGMLDEFRRVAQSLTFHAPRIPVVSNLTGDVATDELRDPEYWVRHVRHAV
RFADGMRKLHELGVRTFVEIGPQHTLTAMGADCVPDGELFATLRSDHEAHAFLGALGKIH
LRGAKVDWSALFTGRKVDLPTYAFQRRRYWLDLPESTGDVTAAGLGASEHPLLGAAVTLA
GGRGLVFTGRLSRKRKPWLAEHTIDGTVLLPGTALVELALHAGEQAGLPDLEELTIQAPL
VLPETGTVQLQVALQDNNLTIHSRQAEEEAWTQHAEGTLRAAKNPPPTWELPADATELDL
GDIYGRLAQHGYEYGPAFQCLGTVWEHNGERYAELHLDTDPDGHGIHPALLDSAFHLLAL
DATETRVPFAWRDVALHATGARSLRIRLTPTGDGAYQMSATDPAGQPVITVGALETRPAD
LGAAKRLDLFRVDWVPAPQGAGIETEVLHANGTDVHEVTWQVATALQEHLTKDSGRLTVV
TPAGDLGTAAIHGLVRAAQREHGDRFALVDTDSMETIPLTGAPELRVRDGEVLAPRLVRA
VANGRKLDPEGTVLLTGGTGALGRRIARHLVRHHGIRHLLLVSRSGGEVPPDLGPDARVV
ACDTADRGALARVLADIPAEHPLTAVVHTAGVLDDAVLTSLTEEQWHNVARPKVTAAWNL
HELTRHLDLDAFVLFSSIAGTLGSAGQAAYAAANAYLDELARHRQANGLPAVALAWGLWA
ESGGMTDSLSTVDHVRLAKLGIAPLLPGDALALFDAALGGEHPALVAAKLDFTADHPLYR
GVARTPVRRAAANNTEALGRLSEAEQRRRLLELVTTTVAEVLGHAGTDGIDADRGLLAMG
FDSLTAVEFRNRLAAETGLRLPSTLVFNHPTPAAIADYLRAELAPEPVDELDRLTAELST
MDSERQAAVLERMARLLQKWDTNGTGNGASADLDSLSDEELFDALDEELGQRGNGRR
>G6G0G2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Fischerella thermalis JSC-11|TrEMBL
MDNQQIHDSVKGIAVIGMVGRFPGAKSVDEFWQNLCNGKESISFWSDEELELAGINPALL
RDPHYVKADARLSDIEMFDAAFFDFSPREAEIMDPQHRILLECAWEALENAGYDPGADPG
LTGVYVGTNLSIYMLNKLSANPELSKSIGSSIFFSNVQDFAATRISYKLNLRGPSINIST
ACSTSLVAVHSACQGLMNYECDMALAGGVSIQSLQKEGYFYQEGGMTSPDGHCRAFDAKA
QGTVFGDGVGIVVLKRLEDALADGDRIHAVIKGSAINNDGAAKVGYTAPSVGGQALAIAD
AVAIAGFNPETITYIETHGTGTPLGDPIEISALKKVFAARTSKKGFCAIGSVKTNVGHLN
IAAGVTSLIKTVMALKHKMIPPSLHFEQPNPEIDFANSPFYVNTKLTEWKTNGIPRRAGV
SSF
>G7LSJ3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Brenneria sp. EniD312|TrEMBL
MDALNLPLILSGESESALTSVAEHWLRKLESLPDDEFTTFCLHQFTIPHAEMRSAIFATD
KAGYLKGLMSLSQGRAARNVLTGNAGAGINPVLVFSGQGPLWQGMTSELLNVLPAYRQSA
DKSGEIFQANLGWNPADALAASEPFSRLKQIQPIQFTISSALADVWRAFGIREAAVVGHS
VGEASAAYSAGYLSQEDATKLVTLWGKELSNIEGQGAMISVAASVDDIAPLLKEWGDRLA
VAAINSNKSVTLSGATTDTNALLDKLTKAGFWAWKVPGGEVAGHSPQVDIVKAAVIAQAP
RNILSSAHAVYYSSVAGARYSAEDFQPDYWYRILRETVLFENSIRALINDGHRLFIEVSP
HPVLTSIIEEHLRAAGVKGAAISTLDRRKNDKESLLYSLAHAFINGASIDWTSVFTQLLP
QQADGYYAALAGVEEASSVAGATSSLSANSVSTTLNDDIDRVALGNRSPSEQYDILLGLV
SREVETLLGETFSSDMQAFRDIGFTSLTVVEFSRGLSIATGIELPSTLVYDHPTPRALSE
YLRQELGLSSSDDGQEAQETRHHDEPIAIIGMACRYPGNVNSPEALWDLLVNERDAIGDY
PSDRGWDVNKLYDPEAGKFGKISTRTSGFLYEAPLFDAGFFGISPREALTLEPQQRLLLE
VSWEAIERAGIDPSGLYGSNTGIYAGIMATEYGSQIQHASEDVSGYGYMGTATCVASGRV
AYSLGLHGPAVTIDTACSSSLVAIHTACEALRSNDCKLALAGGITIMPTPGVLIDFSQQR
VLAPDGRCKAFSTSADGVGLSEGIGMLLLEPLSQAQANGHKVLGVIRGSAVNQDGASNGL
TAPNGSAQQKVIRHALANAGLKSQDVDVVEAHGTGTRLGDPIEANALMATYGRQRSAEQP
LLLGSIKSNIGHTQAAAGVAGLIKMLMAFRHNMLPRSLHITEPSHEVDWSSGAIKLLSAS
QPWPQVGDRPYRAAISSFGVSGTNSHLIVEQPPRDPIDHANAVAVSAPQEMLWPIAAKTD
TALRKKAAQLREYLASNHEIDPINVGYSLGISRSQFPYRAAVRGQSKEALVKGLQALENM
QDDSALTVGTSPANESGKLFFVFPGQGSQWPEMGMELYNNFSVYRQAIDEVDSALRAYVD
WSLIDVLRGNPGTPPLDRVDVVQPALFAVMTALARLWQSFGFTPHAVVGHSQGEIAAAYI
ASALSLQDAIRIVALRSRLMLSQSGHGAMATLGLSEEQTRAFLSPDEGEITLAVFNSPTS
TVVSGDTRSIETLLQRCKKARVRAKRIAVDVAGHSPQLDTLRPILMELFSSVKPNATRIP
FYSTVGGHVSDAPLDGTTLGAKYWCDNLCHPVHFFNTVSALSKNGKVTFLECSPHAVLLP
ALEETTDNTATIVGSMQRNKSAVECLTQAMAHLYVSGHSINWRALHPDASLVDIPTYPFE
HRHYWLTPPTASNVVTVGQRPTEHALLNAIIDLPDDEGVLLTGRIGLSSQPWLADHAATG
VALVPGTAYLDMVSYAALLTDHHRIAELVIQAPLVLPEQGELDLQLRVGRIDEQALRAVT
IHARLHNDEALDATEWTLYANALLQRGVSKQERPFDNVDWPPAGAEPLDLTRLHQRLSAA
GYEYGAAFKGLSAAWRHGDSVYAEASLPEELSTNGHLLHPALLDTVLHTIALPDSEDDDA
TTLRLPFALSGITLADKQPRQLRARLNLKTNDNISLIATDETGETVISIETLNLRETTRD
KLRNQLRIQPEYDLLRTTWSPLPSASKVKEAPATASWGLLESDLDGTSPLDIAVRYESLR
ALSAGLTSSTLPTVLVWPLPVSDSAKTDNPPYTTRSLCEQVIEQLQLWLSDERLANTTLL
VITRRATEHASHECLDVAHSAAWALLHSAQNENPGRIVLLDTDSPLTDTGLLSAALASDR
PQLAQRQGQLLIPHLARTVKTGLLTPPSDSALWRLDISDTGNLDNLMLKPAPEANAPLGR
GQIRLSVRAAGVNFYDVVCALGLIAPQHEFGTEAAGVITEVGPDVKDFNIGDRVMVLTEG
AFGPTVIANQTTTFHLPENWTFAQAAGVPIAFLTAYYALTQLASLRKGERVLIHAAAGGV
GQAAIQLAHHLGAEVFATAHPDKWPILRQLGIAGDHIASSRNLEFTGKFRPQLTGKGIDV
VLNSLTGEFIDASMSLMASGGRFIELGKTDIRENFPTDLTYHYLDRPDSSPKQTAEMLTT
LLSLMRAGSLAPLPITAFDIREAIQAFRLMQQGRHTGKVVLTFSQPLNPDGTVLITGGTG
TLAGLLAHHLVEAHQVKNLILASRRGARADGAAQLKAKLENMGATVEIVACDTTDPLALD
KLLAAIPDAHPLTGVFHTAGVLADATIANLTAESLDTVFSPKIDAVWHLHQKTRTDDLAA
FVLYSSSAGTLGSPGQGNYSAANKALDTLAHNRRREGLCATSLAWGWWQPVTELSSRLSE
TDNARIARTGLAPITPEHGNAMIDAALALPYAVYTAAPLNPQMLRKNMQSGRLHPLFERL
AGPALARRASSGGEKAPDLRQSLSPLEPGARLKQLQVTIVDNIAGILGLDNGSLLVPEQS
FKESGIDSLMALELRNRLSAISGLRLPATMTYDYPTPVALAEYLDAELFSGLDMTMNETI
TEENELYVRERIAGIPLASLRDAGLLEKLIQIADGTVPVEKAPRNVQLTDIEFASIDELV
SMALSDKDNAL
>W5W4T1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Kutzneria albida DSM 43870|TrEMBL
MGDPTAQDLGGSGDIAIVGLSCRLPGAADPGRFWELLASGGDAVGRPPKQRWGAEWGGFL
DEVDRFDPAFFGISPREAAAMDPQQRLALELAWEAVEDARLLPDALRGSHSGVFLGAIWG
DYETLTHQAGALGHQTLVGVNRGVIANRVSHVLALHGPSLTVDTGQSSSLVAVHLACESL
RRGESELALAGGVNLSLAPESNAVLSEFGGLSPDGRCFTFDERANGFVRGEGGAVVLLKP
LARAVADGDRVYCVIRGSAVNHDGADEDLVVPSVRAQRGVLAAAYRKAGVDPGQVQYVEL
HGTGTKVGDPIEAAALGAVLGRGRTGSALRVGSAKTNVGHLEAAAGAVGLVKTALSVFRR
QLVPSINFERPNPRIPLDELNLQVQQEFEPWPGEGPLLAGVSSFGIGGTNCHVVLGEGPA
PSQAAEAEPALVPWLISGRSREAVRAQAAKLVSHVDGLNPVDVGHSLASSRSAFEHRAVV
VGTGEELLAGARALAAGEPWNHLAEGVADAGGKVVFSFPGQGSHWIGMAEQLLEQSPVFA
AKMAECAAECARFVDWSLLDVLRQVPGAPSLERMDVVQPAAFAVMVSMAEVWRTLGVTPD
AVVGHSQGEVAAAQVAGALSLEDAFRVMALRGKAIRDQLSGQGGMAAVALPVERVEELIA
PWTGALSIGAVNSPSSTIVSGSPEDVAALVEQCTAQGVRARVVVIDYASHSARVEVIRER
MIADLASVTPRPGQVPMFSTVTGDWIDHSKLNGEYWYSNIRHTVRFRDAVRGLAETGHTV
FVELGAHSVLTLATQETLDACEVDNPVVVGSTRRGDGGLDRLLTSAAELYVRGVPVDWSQ
CFGDKAKLVDLPTYAFQRQRYWVGESTEQQVSQSIEDPTELVRAHVAAVLGLSDASTVQM
KRTFKDAGYDSVMSVELRNRLSTATGLRLPSGLLYNFPTPTELVAHLQDQLSGQRNLARQ
VVAAKVSEEPIAIVGMACRYPGGVRTPEQLWQLLADEVDAISEFPTDRGWDLRELYHPDP
EHQGSSYARHGGFLHDAAEFDPAFFGISPREATAMDPQQRLLLEVSWEAFERAGIDPTTL
RGSQSGVFVGAMSQDYGPQLHQGAEGFDGYLLTGNTASVASGRLAYTLGLEGPALTVDTA
CSSSLVALHLAVQALRNGECSLALAGGAAVMSSPGIFVEFSRQRGLSPDGRCKAFSDSAD
GTGWAEGVGMLLVERLSDAQRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQERLILQAL
ANAGLRPSDVDAVEAHGTGTTLGDPIEAHSVLATYGQDRDRPLWLGSAKSNIGHTQAAAG
VAGVIKMVQAMHHEVLPKTLHVTEPSSHVDWSAGKVELLTSAQPWDSEVRRAGVSSFGVS
GTNAHVIIEQAPATEPEPVGEDAVVPWPVTARSAEAVQEQVDRLRNEVSGQRSVDVGYSL
ATGRAEFDHRAVLIGDVRVDGVVLPQGKRVFVFPGQGSQWVGMAVDLLGSSPAFASRMAE
CAAALSEFVDWDLVSSLSDPAAFERVDVVQPMSWAVMVSLAEVWRSHGITPDAVVGHSQG
EIAAACVAGALSIQDAARVVALRSKAIAEVLAGRGGMVSVALPLAEVEPLLDERISIAAF
NGPSSIVVAGDPQALDELVASCERARRIPVDYASHTAHVELIADRLAEVLAPISPRTAEI
PFFSTVTGDWIDTGALDAGYWYTNLRQTVLFEKAVRGLADSGHTTFVEVSSHSVLTSGLQ
DVVDGTVVGTLRRNEGTLVRFYTSLAELYVRGVEPDWSAIFPADARRVDLPTYAFQRQRY
WLEAPKPRSAADPVDAAFWAAVEREDLESLSASLAVEQSALGEVLPALSTWRRLQREEST
VDSWRYRITWKPLNSAPGRLSGTWLVIAPEGADTSLLEGSGAEVLVNAPLDGLNPAGVLS
LLECPSETVKLVQDLGAAGIEAPLWVGTRGAVSTGDADPLTNPLAAQLWGLGRVIALEHP
KRWGGLVDLPERLDERATARLWAVLGGIEDQVALRASGAFGRRIVHARTEGAPPARRWQP
RGTVLITGGTGALGTHLARWLAGQGATHVVLTSRSGRAADGLTAELAAQGCELVVAACDV
TDRDSLAALVTSLTTQGSVIRTVIHAAGISPLAPVEGLTAEEIAEVAAPKVTGSLNLVEV
LDGTQLDALVLFSSISGTWGVADHAAYAMANAFLDAFAQQQRDRGVPALSVAWGPWSGGG
MIAEELQDVLRRRGVPVIDPEPAIAGLRQALNHQDTFIAVAEVDWERFVPTFTTLRPSPL
LDELPETARLSQAEVKEETGSSLHGKLSGLPAAEVDRVLVELVREHTAKVLGHADPALVD
TERAFKDIGFDSLTAVDLRNRLTEATGLRLPSTLVFDHPTPEALAAHLRSEVLGSVQAVK
DDSVVAASTEDPIAIVAMGCRLPGGVRSPEDLWRIVAEGADVMSGMPTDRGWDLTGIYDP
NPDAPGTTYVRTGGFLYDSGEFDAELFGVSPREALATDPQQRLLLETVWETIERAGINPQ
SLRGSRTGVFVGLTEQYYGAPNRRSPDGDEGYLVTGDVSSVASGRIAYVLGLEGPAITLD
TACSSTLVALHLAAQAVRQGECELALAGGAMVMATPSQFLGFSRQRGLAQDGRCKPFSSR
ADGFALSEGVGVLMVERLSQARQHGHPVLAVLRGSAVNSDGASNGLTAPSGPAQQRVIRQ
ALASAGLRPSEVDAVEAHGTGTTLGDPIEANALLATYGQDRDEPLWIGSVKSNIGHTQTV
SGISGVIKMVEAMRHGVLPRSLHAEAPTEHVDWSTGKVRLLDENRPWPAEGRPRRAGISA
FGISGTNAHVIIEQPAEPEPVEPAAATEGFVPWVLSGHTPEALRDQAHALREHLLANPQL
RPADVARSLASTRASFEYRAVVLAEALNTGTQALAALDNSPNVITGSARAGRTAFLFSGQ
GAQRAGMGRELYEAFPVFADALDAVLARFDLPLREVMFGESELLNQTEYTQAALFAIEVA
LYRLVESWGLTPDYLIGHSIGELAAAHVAGVLSLEDACRLVAARGRLMQALPTGGAMIAI
QATEDEVRPLLTDRVSIAAINGPRSVVVSGDEDAAQAIADQFADRKTRKLTVSHAFHSPR
MDPMLAEFKSLADQLTYSLPIIPIVGNTEGDPTTPEYWVRHVREAVRFHEGITKLHELGV
SRYLELGPSGVLTAMAQDSLPEGEAVLVPALRKDRDEVFAITSAVSTLHVHGFSPDWERI
VQGEVVPLPTYAFQHQRYWLYDKAGSAPTSKVDAWRYRIQWKPVTAGGKALTGNWLAIVP
MGHSALADALRAQGLTVTEDWTSIAGHHDGILSFLSLDELPHPVHPSMTRGTAATVELVN
AGHSAPIWCVTSGAVSTGPEDPVTSAAQGSTWGLGAVLGLDHPDRWGGLIDIPADHTDDT
IAQLVRVLADPAGEDQLAIRASGTYARRMVHAPRLRAGNGWQPRGTVLVTGGTGALGGHV
ARWAARQGAEHLILTSRRGREATGAAELESELIELGARVTIAACDTGDREALAKLLAAEE
VDAVVHTAGVAQEEMPLSRMSLAEFAEFGRAKRGGAMYLDELLADRELDAFVVFSSVSAV
WGNGGSSAYASANGFLDGLAFQRRARGRTATSVVWGAWGGGGMVDPATEDKHRRHGVPVM
DPELAISALQQAVEDDETQLIVADVVWETFAPALSFARPRPLLHDLPELQEEPATEVPQQ
GNDLVQRLLGMSEEDQLHTLTELVHAETAHVLGHSGTSSVRGGKAFKELGFDSLTGVELR
NRLNAATGCTISSTAVFDHPTPKALAAHLREELLAGAVPELDVLGELDKLERALANSAPD
GELRAKIGGRLQALLSQFGGGSPAVTDEDLDLELASDEEMFDLIEKELGGLD
>A0A1Q2ZQT3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MAHTEEKLLEYLKRVTADLRRTEHRLHDLEAAGHEPIAVIGMACRLPGGIRSPEDLWDLV
ATGGDAVTPLPGDRDWDLDALYDPDPESTGTSYVREGGFVQDVGGFDAAFFGIGPSEALT
MAPQQRLALETAWEAIERAGIDPLTLRGSDTSTFIGCDGLDYAFGDVEVPDGTTGYLTIG
NSGSVTSGRVAYTLGLEGPAVTVDTACSSSLVSLHLAVRSLRTEECALALAGGTYVMATP
APLIGFSELRGLAPDGRCKPFSAHSDGMGMAEGTGVLLLERLSDARRNGHDVLAVIRGSA
VNQDGASNGLTAPNGPSQERVIRAALADAGLSPEDIDAVEAHGTGTVLGDPIEAGALIAA
YGRGRPAERPLWVGAVKSNIGHTQIAAGVAGVIKTVLALQHEVLPPILHVGVPSGHVEWD
GSGVRLLTEGVEWGRGERVRRAGVSSFGFSGTNAHLILEEAPSVEGAGVSGGEVSGVVPW
VVSARSSGALGEQVRRVGELEASAVEVGWSLVTARSVFEHRAVIVDGDMVSGVAGDIGPG
PVLVFPGQGSQWVGMGAQLLDESPVFADRIAECEQALAPHVGWSLTEVLRDGRELDRVDV
VQPVLWAVMVSLAAVWEGYGVRPAAVIGHSQGEIAAACVAGVLSLQDAARIVAVRSDALR
QLQGRGDMASIGTGPDEVRALIGDERPGVSVAVVNSASSTVISGPPAEVAAVVSEAEARG
LRARLIDVGYASHNAQIDELAGQLEERLSGVRPVAVSDVAFYSTVTAGRIDTDALTAEYW
VTNLREQVRFAETLEALQADGYHLFIEASPHPVLVLPMEETIEAGTVVPTLRRDQGGTKQ
LTLAAAQAFTAGADINWRRWFPTPQHPIDLPTYPFQHHHYWLKRTRPHPPTPGAQPTASE
AQLWRAVEERDLGLLSQTLGPEEGSEEAVQALAPALPVLGSWRRRHQEQATIDSWRYHVT
WTHVPDSGSPELGGDWLLFVSAGQAEHPAVQAVFDALTKHGAADVRLCSVEPRTDLAPVR
TDGLAGIVNLLALDEDPHPDHPAVPSGLAATIALVQALGDTGVPLYTVTQGAVSTSAADP
LGRPVQAQVWGLGRVAALEYPRLWGGLVDLPARIDHRTLPRLAAALSPQDEDQIAVRSDG
VHVRRLAHADPVGIEASWRPEGTTLITGGTGGIGAVLARWLAHQGAPHLHLTSRRGPDAP
GAHQLTTELTDLGTHVTVTACDVSNRQQLRDLIDTHPPTAIIHAAGAADLTPIGELTAAH
LGGVLGAKAHAAWNLHELTRGLDLSAFVMFSSGAAVWGSGQQGAYGAANHFLDALAEHRR
AQGLAATSVAWGPWAEAGMSAGEESLAYFKRFGLLPLGSELCVKALHQAISSGRPTLTVA
DFDWARFTPTFTAQRPSPFLADLPENRRAAEGGGSDAELSAFRAELEKTPAAQRQDFLVR
QVRAYAAATLGRAVEEVPAVKPFQELGFDSLTAVQLRNQLNSATGLALPPTVVFDHPTSE
ALATYLREQLGVEGEAGEGQVLTALDKWATAYDAAGLDEAARRRVVGRLRALVSKWSPAA
DGSENGGHDDLEKASADDIFDLISSEFGKS
>B7K7V0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Gloeothece citriformis (strain PCC 7424)|TrEMBL
MGLEPIAIIGLSCRFPKSPNLADYWQLLRNGIDAITEVPEDRWPSLAYFDSTPATPGKMT
TRWGGFLDKVDEFDANFFQISPREAQLIDPQQRLLLEVTWEALENAAIVPETLADSQTGV
FIGISNSDYNKILSKDIFRLNAYYGTGTALSIAANRLSYFFNLKGPSLAIDTACSSSLVA
IHYACQSLANHESNLCIAGGVNLILSPEVTISFSHAKMMASDGRCKTFDARADGYVRGEG
CGVIILKRLQDALNDGDNIYGIIRGSAVNQDGLTNGLSAPNGLSQQAVIRQALKAAKLKP
DQISYVEAHGTGTPLGDPQEFKALTTVLKEGRSSTPCWIGSVKTNIGHLESAAGIAGLIK
VVLALQHRLIPPHLHLENLNPYISLKNTPFSIPTQGQPWEVDTPKRYGGISSFGFGGTNC
HLILEEAPAKSLKTASSSQNQPQERPLHLLTLSAKTEPALLELARRYHHHLVSSPTLPVG
DLCYSANTGRTQFEHRLAVLASSTEQLREKLENFVNPKTEVSGTIEGKVSGRKPPKIAFL
FTGQGSQYIGMGRQLYQTELTFRSNLDTCEQILRPYLNKSLLDILYSDNGELDTTAYTQP
ALFALEYALAQLWMSWGVKPTAVMGHSLGEYVAACVAGVFSLEDALKLVAQRAAKMQALP
PNGLMIVVSASEDWVKSVIAPYVPQVAIAASNGPNNVVISGQSQEIESIKTTLEAQGIKV
TPLKVSHAFHSSLMKPMIEEFRAVAQTVTYSKPQIKLISNVTGQVASPEIATPEYWCRHI
LEPVRFAAGMETLAQQGCRVFIECGPKATLLGMGCACLPEAEKLWLASLRPQREDWQQIL
ESLSHLFIAGVPLDWASFDKDYARRRLSLPTYPFRRQRYWIEESTSLNSASDLESLSLNL
LKPEKINPLVQQLELSGEFSESELKLLPKLASVLAEYYQKHLKEDGGDSQPSSMKNGSSM
SLNGGQSPIATPEKKSIQEQYLSANSQERKPIIRTYFCQLLNRITGISQTDIQWQNPLSN
LGIDSLMASQLRKEIETDLGVAVPVEFLANLSLEQFLEQIILLMEKQSPSLSLPATNSSN
LWFPWLGKNPQARLRVFCFPYAGAGASLFREWSKDVPPDIEICPVQLPGRENRFQDPPFT
NLKALIQTLGTLIMPHLDIPFAFFGHSLGGLLGFELARELRRQKASSPVHLFVSASRAPQ
IPDFSSPIHTLPDPEFKQAIERFKGTPKEVLENAELMALFLPTLRSDFALLETYFYSGGQ
PLECPITAFGGLEDSQISRELLEPWHKQTQSHFQLTLIPGDHFFLQTARQKLLSIIVETL
VPTLTVKKGNNNHDFYC
>Q3M9X8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Trichormus variabilis (strain ATCC 29413 / PCC 7937)|TrEMBL
MFAAENNNTAKIAIVGMDAFFGECNGLDAFERSIYDGKQHFITLPPKRWYGIDEQKDLLQ
EYGLTDGKAPVGAYIKDFDLDTLAYKIPPNEVEKLNPQQLLLLTVADRALKDAKIPEGGN
VAVIIAAEAELSVHKLQQRWDSSWQVKDGLNAAEITLPSTQVSQLESIVKDSVHHQVEIG
EYLSYITNIMASRISSLWNFTGPSFTLTAVESSAFKAVEVAQMLLMTQEVDAVVVGAVDL
AGGVENVLLRSQTAPINTGANTLSYDQKANGWTVGEGAGAVVLKRHQQAIENGDRIYAVI
DAISIGQSHTKVYGGSVNQACQQALKMAGVPPEQVKYVEVCASGIPQEDEAEIAGLVQAY
PSVGDGLHCAIGSVKANIGHTFVASGIASLIKTALCLYYRYIPATPNWSGVKTPQAFEGS
PFYVVTESRPWFLSKNASRRIAAINGMGCDGSYAHVILSEETNQAERPNQYLEQMPFLLF
PVAGDDRTSLLEALDKLQKSIAESADFSRSASLAFTTFQQQSQANYAVSITGRNKKELLR
EIESARKGINTAFDKGTDWQTPVGSYFTAQPLGKKGEVAYVYPAAVNSYIGIGRNLFRLF
PKLHDNSFVKSLYKRAADIERLVFPRSLSKLSTRQLEQLEKKLLSDSLAMFEAEIFCTRL
LTTIIRDDFQVHPKYVFGYSLGETSMMVAQGIWSNFSEVSNSFNSSTLFGDRLSGPKNSV
REYWGLPKAATASGDNLWGNYVLMASPVQVRDAIRNEPRVYLTQINTPEEVLIAGDPAAC
QRVIKTIGCNSFTAPFDHVIHCQAMRSEYDEFVQLNSLPVQDIADITFYSAAEYQPIKLE
TGVVAKSLATGLSQELDFPKLVNRIYDDGAKIFIEAGPGSVCSRWIDKILEDKEHITVSL
NRRGIDDHTSFVKALAKLVSHRVNVDLSPLYSPVIETSNLNKVTLRKITVGGDSISGKIL
SPENLQLFAEIREKKQQNIAPSGNALGINSTYLSHQKSLPKPKPFSAENIIEHGLKPEEP
LKSSELTATQPAKPSDFLSNTTTDIEFATIINMLDLNKAQYQKLNANNLQITQNHTAFLK
ARQDFSQQMSEIIQLQMVCAEDLLQEDGN
>Q3M3K5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Trichormus variabilis (strain ATCC 29413 / PCC 7937)|TrEMBL
MVNMKTVENQEPLDGVAIVGMVGRFPGAKNVQEFWGNLCAGKESTTFFQDEELDPSIDPH
LVQDPSYVKARGIIPGGETFDAAFFGINPREAEVMDPQSRVFLELVYEALENAGYDAEAY
SGLIGLYAGCGQNTYFANHICGRQEIIDRVGEFQTMLANEKDFLTTRAAHKLNLKGPAVS
ISTACSTSLVAVIQACQSLSNYQCDMALAGGVSMTTPQNSGYIAQEGTMLSGDGHCRPFD
AKSQGTMFNNGAGLVVLKRVEDAIQDGDRIYAVIRGFGINNDGADKVSFTAPSVDGQAEA
IAMAQAYANFHPETISYIEAHGTATSLGDPIEIEALTQAFRIHTNSKQFCAIGSLKSNVG
HLVAAAGVAGLIKTALALYHQQIPPSLNFEAPNPNIDFANSPFYVNTQLTPWPQGETPRR
AGVSSFGVGGTNAHIVLEEAPAILPSNLSRPSQLLLLSAKTSTALETATVNLQEHLRNNA
SINLADVAHTLQRGRKAFNYRRFVVCQNTKEAITTLQSLEPKRVFTRHTQVRDPEIAFMF
PGQGSQYVNMGFNLYSREIVFRQVVDQCAEILKPILGRDLREIIYPVATDIETASTALQQ
TCFTQPALFVVEYALAQLWQSWGVKPQAMIGHSIGEFVAACLAGVFSLEDALMLVANRGR
LMWELPRGAMLSVRLSAPEVEKRLAGELAIAAINSPSLCVVSGTTEAIAAWQTQLETAEI
VCRLLHTSHAFHSPMMEAIVAPFAELVGKVKLSPPQIPFVSSVTGDWITPEEATNPMYWA
QHLRQTVRFADGVKTLWQQPERLLLEVGPRTTTTTLARQQAKDIKQQITIASLSDNADNE
AEWTALLQAMGQLWLAGVTINWNNFYQEERRQRIPLPNYPFERQRFWIDPLPHPNRNTNH
KPAHYQLEKTQTMSAQTTLISLLKEIIEETSGLEIASVDASTTFLEMGLDSLSLTQVGLA
LKKKFKVKVSLRHLLEVYPNLATLADFLQQNLSAEALSALVPSETTSPSATLSLQEVSTN
GSNGKNGKNGSTPSPMLLVPPTSTNGNGSKNGSLPQVSLPNVASSALEGVINQQLQIMAQ
QLALLGNNSQPVTVPAVNGQNNGVKSEKPVTQSNQKPEPQDSTENLPKKVFGAGARIETT
QTKTLTPQQRTYLDSIIQRYTQRTQKSKEYTQTNRPHLADPRSVSGFNPTMKEMVYPIVV
SRSSGSKLWDIDGNEYVDLSNGFGLNLFGWSPAFVTEAIEAQLKLGMEIGPQTPLVGEVA
KLMCEITNFDRAAFCNTGSEAVLGAMRLARTITGRNLIAIFSGGYHGILDEVIVRGTKKL
RSIPAAPGIPQEKVDNILVIDYDAPDALDILKSRADELAGVMVESVQSRRPEYQPREFLQ
QLRQFTEQEDIALIFDEIVTGFRIHPGGAQAHFGIKADIATYGKIVGGGLPIGVIAGKSK
YMDALDGGFWQYGDDSVPEVGVTYFAGTFVRHPLALAAAKAVLQHLLKNGPSLQQQLNAK
TDQFVVELTDYFQQMQAPYTVHNFGSLFMVKSAPEFLYGDLLFYLMRDKGVHIWDHRPCF
LTTAHSDADLSLAMAAFKESIAEMQSAGFFSAPTPTTKGSPESSKNLRNRPPQPGAKLGR
DPEGNPSWYVPDPQRPGKYLQVSSVS
>N1NQH5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Xenorhabdus nematophila F1|TrEMBL
MVNNVTGLEVAIVGMAGQFPGADNVHDFWEMLCDGKEGISRFTQETLENNGISPEEYLNE
DYVPAKGIINKPYHFAADYFAINHPDAEKMDPQTRLMIETCWQALNHAGIDAKDYPGEIG
VYAGAGNQWSWFNTLNTEFNSSAEQFHVATLNDSAFCSRISYLLNLRGPSVTIQTACSTS
LVAVHTACQALQAGECDIALAGGVSVTHPHQAGYRYQEGMINSIDGKTRVFDEQAGGTVF
SNGVGVVTLKRLTDAIEDNDRIYAVIKGSAINNDGNDKISFTAPSALGQEKVIRAALNVS
EIDPASISYIETHGTGTVLGDPIEIAALDAIFHGQQSCAIGSVKSNVGHCDTAAGVISLI
KLSLCVYFKTLVPSINFEKANKKLALEKTPFHVNTQTKLWVTQNNTPINAGVSAFGVGGT
NAHLVLQEFSERTESVSAEHLNYQELPNRIEFKPAIKKETASAFNEEQDNEEQEVSVEFA
EKIDINAILKEILNVLTAYFPNKNISKDDNFFDVGASSLDIVQLHEKINAHYAIKLSIND
LYRYTTCQKISEKIYDVINEMPRKTTRKLKKVASGKTSNRIKTTHHDYPENAIAVVGISG
RFPGSHNVREYWKNILSGKEGISFFTDDELIDAGIPEYIFKNKHYVRAKGIVENALDFDK
TAFGYTMREAQYMDPQFRLLHEITWEVLDDAGYGNPKYRPVTGLFASSGSNYEWLDRVKE
EVKDTTEQFSIGLLNDREFLTTRIAYKLNLTGPAVTVQSACSSSALAITLACQSLRVNQC
DLALAGGVSITVPVKSGYMYVNGMVNSADGHCKPFSEDASGTVFSDGIGMVALKRLEDAI
ENNDHIYGVIAGYGVNNDGYEKAGFTAPSANGQAACIKQSLAMAGISANDVGYLEAHGTA
TLVGDDIELEGVKSALSVADDNPSICHIGSVKSNLGHTDSAAGVAGFIKTLLTVKHKKIP
PTCHTEKNDHGLLQGTRFRLINAATDWDNNNDIRTAGLSSFGIGGTNVHITIQSILEQIS
SEQDRPELITLSSKSKAGLIKTAETLGQFLNADTHTKSLSDIAYTLQIGRGEHEYRTSFV
IDNVKELKNALLHVKETNNIAEISFDQTPGIVFMFPGQGAQYINMARDLYNELGIFRTLL
DECHEYLFERFGINLLALLYDEKNQDSIEKLRNTQFTQPIIFAISYSLAKSLEALGVEAK
AMIGHSIGEYVAAAMAGVMTLDEALELVAVRGLIMQECEPGAMLSVSAGREEIEPYLTDE
VTLATVNSSTACVIAGPQTEVEKVQLVLADKNYRTRLLETSHAFHTAMMRPAVGKFKQAL
KKIKWRKPNKAYISNVTGQWITAKQANSIDYWVAHLCETVEFHQGIMTCLEQPDLNAFIE
VGPGRTLSTFVKQIIGTNTDISVINVMRHPLEKENDRAYLLKLLGQLWMKGYAINWSVIY
QDVKPGRVSLPGYQFISEKMGPGNSPAGSNQAEKITETRIQKNTISDWLYGEIWQDALLP
DKSNQSEVKTALCFVPNMEWCEPLSRHLNVDEKSIRFVLSGDDYTSVNNVITLAAGEVSH
FEKLFHELKENQLQPDSVIFAWPLSGHRDLKNTWFSAITLLQAWATVGNMGDFRLLLVNT
EQPESGMLKGLVKVITQEVSKCHPRLVQINTTESIENTCEILTEELLATDGRFIVCRTDG
RCSEQVYERLNVEPQKKHSLLKQQGTYLITGGLGDLGLLFAEYLLKEYQATVILSGRREL
PDRHEWQQATQSDLSTTNLLQQLNKLADLGRGNVVYYPANVADKSAMQRLLQTIDEQHGV
LNGIICAAGVTEGDSFQGINRITLDACSPQIETKVEAYKILAELTEHQPLDFCLLCSSIA
SMLGGLSFSAYSSVSAFADAFARQQNQQGKLWISINWDGWVFERNDSGDALGSSLSQLLI
EPDEGIQILERVLQSPLRGQIIVSTGDLNQRFEQWVGSHLKAFDINKISKSHRKTISKDQ
ITETIISVWKDFLKITQINREDNFFELGANSLDLVQVNKRLTDALDIDISVVDMFSYPTS
ELLADYITSQYGTVSTNDSQYEQPDHSDESAYVAEYLVKPDTVFDKHIAIVGMAGKFPGA
EDIYEFWDNLCYGKESISIMSKEELIESGIDSDLLDDPNYVRAKGIMPHSGEFDAEFFGY
TPYEARQMDPQVRAMHICSWQALQDAGISPKNNKLKIGLYTAASGNLPWLAQAMATAEGS
AGQYSAMVVADKDYMSTSVSYKLNLSGPSMVISTACSSSLVAVNEAIKSLRTGECDVALA
GGVSITLPIKAGYLFEEGMIYSKDGKCRPFDIQANGTVFSDGVGVVVLKPLKQAIADKDN
IYATIIGSGINNDGGMKVGYTAPSTKGQVDVIQAALRDANVSSESIHFVETHGTGTNLGD
PIEFNALKQAFSTDKKSYCRIGSVKSNIGHLNFASGVTGLIKAALSIKNKVLPPTLHFAR
PNKEMDIANSPFMVNNQYTELHDNKYPIRAGVSSFGLGGTNVHLVLEEYRADQNKLSGKN
ANNRLPLILSAPDEKSLQSYKKQLKQVIQSDNQKLNISDFTYSLMQRETMASQFIAVVNN
RDELINALSSTEKDNINLSRGIKRKVVFLFPGQGSQYIAMGQDLYKNNMLFKQWCDKGFV
IAKDYCTTDLKALLINGSQEQPIYETEFVQPLLFIIEYALAQVLQSYDITPDAMIGHSLG
EYVAATLAGVFSYEDVIKIICIRGRYMQSTETAAMLSVMASSDKVKEILPENLDIALDNS
SELCVVAGSDEAMTQFEEICHTESIKTKRLEIKRAFHTRYMDPVLEEYGQALKGITLKKP
QIDFISNVTGEWVDHKRVTESDYWVDHIRQPVRFRQSIATALENEHCLFIEVGPGRGLST
LVQNHSDYNANHACLSWQGHKTKGMSHHHELIEKLAMIALYGIRVNWQQEINEQQPELIH
LPPTPIRGKEYPTDIKRLQALFSGNPTSVVEETEKEEKINTNPISRGKVPESAIDQLGAI
WKLILGIDKIENSDDFISLGGSSLSAVQVIAKAKEINLPININMLLSGKTLLEINQLLGN
ENNIEYKTQSWTFNEKFSPEFYPEYASCLYSAVREKLKHEHQLDCSDALMLVSDGSPLLG
IVLQQCEKETQLSHQEVNFGHILGWPALDDSYSFSYAKKFFDDYESYRHYCEKELSLGHV
VIVTGSDYYLPFSPSYGLSEAEYIERPLFQDIVLDDEVIPHAFVLVGKTDSGYQVYDGSF
QYFGEITEQEFEKTVIGFRGLDFMQSHEVFKKSRPYLVITVNCDGDFPDSEAQQKIILNN
LINDFRKEEEIKYPENEFSCYIGLAAIEKLIETPALLTNSAVADLEEIFVRWRDQISSLK
RFLMIARSASAIQLESSFSLIQEKMEDLIVSCKDHDNDGNKVNCLTQIKSGLDSVINIIS
E
>F4C2F4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Sphingobacterium sp. (strain 21)|TrEMBL
MKTAKLIGITPFELPDLALLKALSKTPFVPVLHIGRNHDQIEKIYDNIKSYKPKSIGLCF
PDSHIPSKELPSSVAYIIMPFSNEISMEAIDVEIIFQVYSVEEARLAKARGAKTIIIKGN
ESGGHVAYEATYILFQHVIQDFDLQSLSVWVQGGIGIHSAAALIGLGADGIVMDNQLSLF
PECKAPQALKNVIEKLNGTETKLVGNFRVLNRPNAPELPQGATFSDLLPYLNGNYTLEDS
YLPMGQDVILSKGLVSNYKTINHLASGLLEAINGHIKQAKTEHVLREDNPLAEELKIRYP
IAQGPMTRVSDLPSFAEAVSLGGALPFVALSLMTGEKAKELIVKTKEVLQDQTWGVGILG
FAPQELREEQSRYILEAKPPVLLVAGGRPSQAIPFEKAGIKTFLHVPSPTLLDLFIKEGA
RKFVFEGRECGGHVGPLSSLVLWELQIERILKEEQLPSFELFFAGGIHDSFSSAFVSIMS
APLAIGGAKIGVLMGSAYIYTKEAVDSGAILPGFQEQAIKQAETVLLETAPGHETRCLQS
PFTSYFEEEKRRLEKDGVDKKQIWESLEQLNVGRLRIASKGIERVSENLIYLNEDVQYQK
GMYMIGQVAALNNKIRTIADLHEDVAKNNYKHIEHAETFTLTETTNHAIDIAIIGMACIY
PGAQDIDAFWRNILDAKNCITEVPDERWNKEIYYDPLDTNGSKSPSKWGGFIPKIEFDPL
EFGIPPQSLAAIDPTQLLSLLVAKRALEHAGYAAKDANKENVSVIIGAEGGNDLANNYSF
RALFSQFFGEIPKEVDESLPKLTEDSFPGVLANVIAGRITNRLDLGGRNYTVDAACASSL
AAIDLACQELILNKSDMVIAGAADLHNGINDYLMFASTHALSKKGRCATFDAEADGIALG
EGVAMVVLKRLEDAQRDGDQIFAVIKGVGGSSDGKSLGLTAPRLAGQTKALERAYSQAGL
SISSVELFEAHGTGTVVGDRTELSALTQAMVKSGAIPQQSHLGSVKTQIGHTKCAAGMAG
LIKSALSVYYGIKPPTINLKEPNGFYNEKTSPFVFTDKAGLWSNPQRVAGVSAFGFGGTN
FHAVISNHVDNKEIPFSVTKQWPAELFVFRGNDYEEASLLLKKTKRLIDLNDSVKLRDIA
FSLATYSNAPVQLSIIADSIADLQFKIDLVLSGTHAKDTYITKEVKGKTAFLFAGQGSQR
IHMARELLVNFPRMRSLLSRYPAYEKILFPSNAFSEESLKKQKEAIKDTRMAQPLLGIID
IAIANLLSDLGVIPDMLAGHSYGELPALAFAGVFNEGDLVALSKGRAEAILASTGDDKGI
MVAVNGDKAMIDQLLSSRKNIYAVNHNSPQQWVLAGESAVMESFMQVLKEQKISYRQLEV
ACAFHSPLIAKAESLYADLLNGFSFKQPSIPVWSNTSAALYPTESTEIKNRLASHIVNPV
LFSDQIEEMYANGARIFIEVGPGKTLTSLTKSILGKEEVVIHTEENGKHGIFQLLVALAQ
YIATGKTVQIDVLFADRQATWLDLDNPEKLKKSSSIWLVDGQMAMPAQGKLPAYSALPVT
KPVINFKELTVQNNTKSDTLSVQGSAEQLTLEYLAGMKMLIQAQRDVLLAYLGQPSMNNY
IHTNPNTVPASMPSLIEKREQSPDPVGKKANENELITSGPKTTKPLSTILMDVVSEKTGY
PKDMLGMDLDLEADLSIDSIKRLEIIGELRIQLSNFQFKNKSQDEMVEQLASIKTLNGLL
GWFDANIINDVNETLTTEITRQQPALQKGDIQDMILGIVSEKTGYPTEMLGLDLDLEADL
SIDSIKRIEIIGELKCKLEAIMPSDEENQEQMEKLSAFKTLNHLIDWIAAKLLANGESKS
LADKEKPFVDTLLGNNELSDTLKRIKFELTDVHALLKQEYPNTLQGAKVAITRDGNLGFL
IKEKLEERGAIVDIVPQEKDLAGYDGLVILDMVASNHRLNIIDAVRMVKSLDMNRVKWVY
VLSDHGAHVDKNEDPKFLRSYQGYTGFIKSLDKEYDQAKCRTIHFINETKEDKIPDLLID
EMLCTDEPSVIYYKDNFRHAVKETNDPLQTANRSPFVMDKDAVVLVLGGAQGITAALTTH
LAKEYPCNYVLVGRSSYPSDVDSNQIIMQSKEEIRKSLIEQGYSKSPAEIEQRTIQLHKT
QQILSSMQAIREQGANVSYHAVDVRDEDALVLLIQELYKKYGRIDGVIHGAGILEDKLFE
NKTADSFERVFSTKVTPLRVLAEQLRNDTQFIVFFSSIASVYGNRGQTDYAAANSVLDHY
AEVLRKKMKGRVMAINWGPWKGAGMVSSSLEKEYERRGISLIPLERGKETFANEIKYGNE
SRVLIMA
>A0A2G8Y5C0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii COUG|TrEMBL
MAKPSPHSQPSIWSEKWAYHSSVPENDAVFKVPKKAWIIVGVPSQHMAEVLLSLKRMGLD
TSRVCGLGAISSMETLQNLVQGGTWAGMLVVSGLWATVSAVESLTETAHILRHYACLSTE
IEVPVLAVVTRGAQRSVVSPETFGQRERPTLESVPQQNQVFGHLEDEVPVHAGLLAFCRT
LRLEMGRCCRRFKPFLYFDTDRLHPRQSKESLDYHLGAVLKWLSRNDVPASFSEQIRPDS
DTLREWDIVIRKQSYFVPRVAPVLLKQPSTTAAGRIQKAKSYIVTGGLGGIGIVVASWLL
RQGAGRIFLWSRRGVPTDDVKETNQWCELNAAMETGRIQTVSCDVSEIEQVRHSIVLAVT
DSILGGIFHCAGTEGKGKLQDVSQQDIADVYASKVEGAWNLHRICSEMSINTNLDFFVLF
SSIAALPGNDAFATYAAANGCLDSLAEHRRSLSLPARSIQWGPWLDAGMAARTPSFERFM
RSRGIRGFHNEEAISHLETLLTADESLTCCAAVHVDWRIYAHIFGSHVPTWLQDVVPGLQ
TSLTPFSESNVPEQMHGSMDIQGVESAVIDVARRLCGAEGIVSASTEISSLGLDSLGAVE
FRNALQEALKIKLPASLLVEYACLKDIIQFIMENCFSDAARSTSDLVPLVTREPAANDQG
FAVVGMGCRIPKNATTTEEFWDMLLHEIDAVCEIPMDRFNIDAFYDPDPEQDKCYTREAA
LLDHPDFFDNTFFNLSDQEVLAIDPQQRVLLEVAYEALFEAGFTKEALLGKDFGVFCAAY
NNDFQFTNLTQGKATMCVFDKGEGRGRIPSLGEAAGYPEPGGFMCFIPNRISYSFGLTGP
SIGIDAACASSLVAFDAAVTKLKRGACSGALVGGVNIILSPTFFLGGCKAHQFSRAGRCK
TFDCNADGLVRGEGCGAAFLLPLDAARETGAFVHAVVRGSATCHYGRSSQITSPNTRALT
RVLRLSLQDASTAPSLVRYYEAHGTATVLGDVIEMSAVKDVFQTGRNAAAPLHMGTVHNN
IGHLDAAAGIVAFLKTVLCLKYRFVPANIHFKSLHPDIHGIDTQLIKYTRESHSIMTDDV
ATGVRKTIFGANLAYGMGGSVAAIITESGDEEADRRSLKAAPRHVWNHRRFPLNTQKFVY
LMGAMGQISMDDMPTPQSDVIHVMKRLSATALNVAFMRKLSPSTCAAGSIRSVFLTGATG
FIGSQVLFHLLQVKRQDPKLGTEDKKLTIYCLVRARDRAHGIYRIRDSLVGRGIEWKHEF
DQQVIPVIGNLEEGENMGLGPKQMQYLEQTVDAVYHAADYVNFAAPYDALRKSNVLSLIP
ILKLCTTYVAKPLHLVSNFAHHLQYFAGFSEDLNIAVDETVSPPLSPASIDRLEQQMPAG
IIGYPWTKWAVEEIIGRMKDVLHERCEEEGQRVSMEESEKKDILSKFQVTVYRLPNSCVY
YNNGYTNFANASLSLVLASAQERMIPPGVLPVGAPFLTTPVDLITGILVKLSMTERKRHH
VYHLVSLRVARRKHVVQAIKWLFPDSVECTADELFRRIDENKENSPAHPLRAAMRFWRRY
WYSSDTDRDSPFPVAVNNVEDDLPGVMATFPSLADTWLRMASYCVKNYHMVRHPFTLAIS
FERLKKAIAGITKQRIDELALPSQTQELLNETCSTEDTTDIAAVKALVEHANLRKYDDCA
VSDVPDPRARA
>A0A5C6C7I9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Planctomycetes bacterium Poly21|TrEMBL
MNTMHITQDDVNRFAQWSGDRNPIHVNPDAAKKSSFGGTIAHGALTTIEALRSLPSELAR
GREIEGLDIEFRGEVRPDRNYPVESSSENETSTVVTVSDGQATRMTVTATYRNGLTVPST
AAVVAWMEEAMQAGDPSSGDDAPVAWQPYDFEAGACHYGRHRFGHHAAAESSLTTTQEKV
LGLCSFIVGMKAPGLSSLFTRLSIDFAAAAADCGDEVAYRLTFRDYEPHFRLLETELEIA
SASGELIATARVQSYVRFPQAEPDPAGYVGELTLPARELASKVALVCGASRGLGAELAAA
LGAAKCKVYLACRHPNESTRALVEQIDAAGGAAVIVAGDVGDAQWCERTKSEILAADGRL
DLLFLNACAAPRFGGVAGSTEADSFSYIAENLALSKIPLASFLSCIAEVSGAVVAISSSF
VDECPAGFADYIGVKMAVEGLVKTAAREHPKVHFLIARPPKLRTSWNDTPTSAMGAIPTA
VAAARIINTVASPDDRTPVEVLDSFPFTEPAIRQVTAEPDRRVVLCSTFTLDPIGNGLQR
WSAELDLHLGIEFAPYAQVLQQCLDPASLMSRSSDGAVILIRVSDWLREWNLDDADAGDV
ERRLRAAAQEYIDAIKTHRSFAAGPTLLLICPGTVSGYLLESLLHEIEHQLRDSLSEIPG
LTLIETRDCHALFEIDGTQNIFDELRDEIAHIPYQDAYYFFLSALIARFVHRQNAPTKKV
IVLDCDNTLWGGVVGEVGAEGVRFDEVHHQLHRRLLQLAESGMLLCLCSKNEEHDVWSVF
DQRSDFGIPRDQIVAAAVNWLPKSQNIQALAERLNLGLDSFIFLDDNPVECAEVRSGCPS
VLTIQWPTDAASATKLLDHFWELEARDATAEDKRRTQLYREEFSRQDSLQSAGNFQEFID
SLDLNIDIQTLSDADLARASQLTLRTNQFNFTTLRRSEAELKALMADPNVVCQTVRVRDR
FGDYGLVGFLIGAAQDDALLVDTFLLSCRVLGRGVEHHMAANLGKIACDRGLSLVNWRHV
PTDRNTPARSFLGLVADAQPPEDAGGVWECGTDAEELSSFHFQAAQADTPTADPKPDASP
TANQSPTLSTRDRERQIERIAQSLSTYAQLEIACGGELTTAEATPANLDEIVEQVTTTFA
KALRRSTGEIAHIDRLEALGCDSLRIVEITVALSKQYPWLPKTLLFEHRSVSEIIAAITE
VASGQATRQLAGRPAINEPRPSAAEIGDIAIVGIGVRCAGADTATELWSMLTEGRSAVVR
VPVQRDSSVGMLQDERDHFAGLVAGAANFDAEFFGVSPREAEYMDPQLRIVLENAWHALE
DAGGLGDQFDVATGVFVGVMYSSYGRFANAVATQTGSLYRCWEGFSLANRLSQVLGCNGP
SLSIDTACSSSATALHYACRSLADGDCSTAVVSGVNLIVDPNRLVQLGRLGILSPSGRCV
PFGDDADGTVMGEGAVSVVLRPLAEAQRRGDRVYAVIKGTGISSGAGSVGFTAPNPTAQA
IATRRAIVAAGVDPRTIGYIETHGTGTELGDPIEVRGLEMAYCAPQLWQSELQVRHQCTI
GSIKPNVGHLEAGAGLMGLIKTALQLHHRTLVPSLTSDAPNPQIPFGDLPFDIQRQSRQW
ESISASRAGVKIDLPRRAGVNSFGVGGSNVHVILEEPDSVPAREDANADRSAHLLTLSAT
STAALRRQAPAWTDSLTTLDRERIADVCYSANVGRKHHPVRAAIVISNEHDAAEQLQRIT
EGLQVHDGMQLTDADTIVNPRIAFLFTGQGAQYPTMMHNLYQQSPVFRAAFDECANGLDS
HLNKPLHEVIFSGNAADREHCIHQTGNTQPALFAIQYSLWRLWKSWGIEADVMLGHSIGE
VAAYCVAGGCSLQDALHLVVARGRLMQALPAGGTMASIGLDFEHTQQAITGKGERISIAA
MNGPMQTVISGTVDAVNQTLEELNANGVRTTPLSVSHAFHSALMEPMLDEFADVLRGLSL
GTPRTPIVSSATGQLITDEMSKPEYWLHQARNPVRFVEAMNTLHAENVTHYVELGPHPVM
LGMGRECLPDVEARWMPSARRGADDWSTLLDSLGRLYVDGLDVDWAGLDMPYSRRRVATP
GYQFDPQRMWLEELENGNLAGPRHDGDQTACFADPISQGETSTSRNATSLTYQLDWQALP
RKLTPSDKETGTWLVLADHAAAALEVAAALTTCDLRCIPAVVAVPHQDVSSVPGPLGAGP
LDSLEVNASTELVVCLSQQALSALIQEHRGTLERIVYADSPPTDISDETPSPYSLSTNSV
FQLSQVVAAIGNTQLPPRCVWMASRNAICVNAADASALRLSSSPLWGFARVAVLEHSSWW
GGSVDLDALEWKEQINRLVDEIRFPCADDQIVLRAEHRFVPRLRPRNAVPTLPNGDVASA
LQLDQGCVLITGGLGGIGLEVANWLAEQGARHLLLSSRSKTPSAAAQTAIARLRQSGVQV
SIVAADISTSTGIDACRIATSGQPLIGIVHAAGVDLRKPIADTSYADVESLLAAKVNGTW
RLHNAFDQQPLQFFVCISSIAAVWGSAERSLYAAANSFLDAFAHYRRGIGKPALSINFGP
WHGAGMADRASLAELSRIGNDGLDANVALQQVADLLAQHETQAVVADIDWARFRPVLESR
RPQPLFAELGQVADSCQATSSRGEIKKESTDSGYPWIEQLQGLSENERHMRLADLLKTEV
ARLLRIKDPQSIALDGQLFDLGMDSLTSAELVIGLRKQTGVGSSTHLLANPTIRAIATTL
MAAIRFGDTSNTDSNVQAGTSNRAEGPDTWISQLAGTDEDRTERLVALLTKDLSRTLGRK
STHDPSATQPLVDLGLDSLGAVEFANRIRDRLQLNQSPRVLDFLHLRALAAHLVQGIPAA
VVAEIIGYSEAVEPALSNFLTQAFPDRPRDLVMPRWKWMFLESAQRLGVDPQVWLFQDGD
KIVGHHGAQLVRFEIRGKQSTTAWLIETMVLESHRDRGVGTRLVIQSLEDMPFNLSLGQT
ENMRAILENLGWKRVAPLQTYLLAINPGRVLKGKLHPAAIPAASAWMRLRGKARRMLSPA
SSVHATVRQVTRYDARHDRLWEKVSGSYGCATVRDASFLNWKYVDQPGQSFTRLEILIDD
ELIACAVISIAESAPPYHYRRAFIVDLVVSTDPRDLQSAIHKTVEHCQGVGVDAVTMHVI
NNRIEQALESYGFLKRPSTRHLLIATDNSIDRQTLLEPHQWLITQGDSDIDRP
>A0A1L7F976|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinoalloteichus sp. GBA129-24|TrEMBL
MTRAGSEPIAIVGISCRFPQAPDPSAFWRLLTDGIDAIRDAPVDRYPAGTAAGYLDEVDR
FDPAFFGLSPSEAAMMDPQQRLVLELSWEALENAGILPGTLAGGPAGVFVGAMAEDYRAL
AGLDGSSGRYVLTGLYRSMIANRISYFLRLHGPSLTVDTGQSSSLVAVHLACESLRAGES
GLALAGGVQLNLVPDGTAHLAALGVLSPDGRCHTFDHRANGIVRGEGGGFVVLKRLADAV
SDGDTVHGVILGSATNNDGGGANLTAPSETAQRDLLRTACRSAGVEPAEVQYVELHGTGT
RVGDPIEAAALGAALGAERSPATPLLVGSVKTNIGHLEGASGIAGLLKTVLALRHEELPP
SLNFERPNPAISLPELGLRVQTARTGWPGPDHPPVAGVSSFGIGGTNCHVVLAGYAEASV
TGEPGAGSGAPGAGLATPTWLLSARSRRALRGQAERLAAFAEEQADLPVEAIGAALRDTR
TTFEHRAVVQAATRADLIEATRALALGEPDPRLTAGVTDAEGEVVFVFPGQGAQWADMAV
ELLDTVPVFAEHVEACSLALARHTGWSVLDVLRGVEGAPDLGRTAVVQPVLFAMSVSLAQ
TWRAAGIEPAAVIGHSQGEVAAAHVAGALSLDDAAKIAALRVGITTDLLADSGGGMLILG
TSAQDYRERFAELAPGVSIAALNGPESIVLAGPQSTLDAFAELVAAQGVRCRGVRAAEFA
SHSPAVEPAEQALRAAFAGIEPRRCPVRILSTVTGDWVDGADLDADYWYRNLRSTVRFEP
GVRALAASGHDFFIEVSPHPILVPAIEDTLAGETRLRVVIGTLRRDEPAVLNLLSGAAQL
HVRGLSPDWNGLLPSAGAERVELPTYAFQRRRHWLDGSAPEGDPEQAARSASEWEALIVR
RLGGIIGDGAAVDPRATFKDLGCDSMSLVELRAQVGATIGRPIPVSVLFSYPTPAALAGH
LAAEQPDDVDLGATEAAGVPDLAEPLAIVSMACRFPGGVVSPEQLWDVVAAGGDVVSDWP
QDRGWDLAGSYDPQPGLPGRSYAKEGGFLTGAGGFDADFFGVSPREALAMDPQQRLLLEV
SWEAVERAGLAANSLQGSDTGVFVGTTTQEYGARLHEAADDSGGYTLTGTAASVASGRIA
YTLGLLGPSMTVDTACSSSLVALHLAARALRQGECSMALVGGATVMATPGVFVEFSRQRG
LAPDGRCKAFAESADGTGWSEGVGVLLVERLSDARRNGHPVLAVVRGSAVNSDGASNGLT
APNGVAQQRVIRRALADAGLVASEVDAVEAHGTGTTLGDPIEAQALLATYGRDRPADRPL
WLGSLKSNIGHSQAAAGVGGVIKMVQALRHGVLPKTLHVDVPSSHVDWDAGAVRLLTEQV
EWPAVDRPRRVGVSSFGISGTNAHVIVEEAPEPAEVVAGPDAEPGVVPWLLSARSPAALS
DLAGRLAEQVGADSDLSPVDTAFTLAVARDAMEHRAVVIGAEPAELLAGLGMVPENFDRA
GSVGRVVLVFPGQGSQWVGMGRELLGCSPVFAARFAECGEALAPWVDWSLVAALDDEGLL
ARVDVVQPVLFAVLVSLAAVWESFGVRPDAVVGHSQGEIAAAVVAGGLSLSDGARVVCAR
SRLIAQTLAGGGGMLSVALPEDEVRSRLTTFDAGADADADAGAGGVSVAAVNGPSSVVVS
GEPVALAGFAEGCESEGVRVRWVAVDYASHSEQVERLEADLLAVLAEVTPRSSEVGFFST
VTGDWIETSELDAGYWYRNLRQTVHFHSAITALAEQGYTGFVESSPHPVLTMSIQDTLDG
PGFLDEDGLLVTGTLRRDDGGLRRLYDSVGQVWMRGYPVDWASAFGDHSRRVPLPTYPFQ
HTRYWLETRQAARRDEAVDDWRYRIAWADLASDAHARLSGTWLAVTTGGHEPDLYTELAG
RGAVIRTVALGEEGELAESLRAAADEPPVGVLLLLGSDDAGPTLVPAGLDAITRLLRALA
EAEISAPLWCVTRGAVSTGDTDRLASPDQATAWGLGLVAALEHPRRWGGLIDLPAQDGDW
AGALAAALTRMDGEDQLAIRPDGVYGRRLVRAPLPAHAGQSFRPAGTVLVTGGTGTLGAH
IARWLARAGADHLVLVGRRGAATDGAPELVAELEEAGTEVTVAACDITDRAAVADLAARL
AAAGHPVRSIVHAAGIGVLEPLSSLGVESMAEVLAAKVGGLRNLDEVFDLAAMDKVLLFS
SISSAWGVADHGAYAAANAYLDAFARQRWADGAPIRSIAWGPWGGGGMIPESLQDVLRRR
GVPVLDPATAVRGLERAAGEDTPFLAIAEVDWPRFLPVFSSTRTSTLFTAIAEEQENTGP
AVPPQGSRIRAELAGRSGAERKRALLELVQKHTAAVLGHTGRESVAGQRAFTELGFDSLT
AVELRNRLTGATGLRLPATLVYDYPSPTELAHHLEIGLFDDGGAAVAPVGAVTVADPAEP
IAIVAMSCRLPGGLSSPEELFEFVAAGGDAIGTFPLDRGWDLAALFNEDPQARGRSYVRE
GGFLQDVAGFDAGFFGISPREALSMDPQQRLLLETSWEALERGGLDPRSLRGSQTGVFVG
LGEQYYGSVLRRDESADESYAVTGEAGSVASGRIAYVLGLEGPALTIDTACSSSLVAMHL
AVRALRAGECGLALAGAAMVMSTPAQFSGFSSQRGLAPDGRCKSFAEAADGFALSEGAGM
LVLERLSDARRNGHEVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALTNSGLEASEV
DVVEAHGTGTTLGDPIEAQALLATYGRDRPAERPLWLGSVKSNIGHTQTVAGLAGVIKIV
ESMRRGILPKTLHVDAPTSHVDWDSGAVRLLTEQVEWPDTGEPRRAGVSAFGISGTNAHV
VLEQAPDQPETAPPPETLPVAPWVLSARSAQALRAQAARLAEHAGSRPELSAMDLGCSLV
AARSALEIRAVLAGDRDELLAGLHTIDTGVVSGPAGRVALVFPGQGSQWVGMGRELLGSS
PVFAARFAECGEALGEWVDWSLVAAVDDEGLLARVDVVQPVLFAVLVSLAAVWESFGVRP
DAVVGHSQGEIAAAVVAGGLSLSDGARVVCARSRLIAQTLAGGGGMLSVALPEDEVRSRL
TTFDAGADADADAGADAGAGGVSVAAVNGPSSVVVSGEPEALAGFAEACESDGVRLRRIA
VDYASHSEQVERLEADLLAVLAEVTPRSSEVGFFSTVTGDWIETSELDAGYWYRNLRQTV
HFHSAITALAEQGYTGFVESSPHPVLTMSIQDTLDALEVDGALVTGTLRRDDGGLRRLYD
SVGQAWALGYPVDWTPAFGDHSRPVPLPTYPFQHTHYWPDVPVPDGAVDSWRYRLEWTSI
DPPENPDSGGTWLLVAPDACRSLAEACARGMESSGQKVVSVEVDHDDRSRLAERLRAATD
DHDLRGVLSLLATDGRPEPDAPALRRGLTGTFRLVQALLDIGVEAPLWTVTTAATAAAGE
PVDHPDQAAAWGFGIVAGLDLPDHWGGLIDLPAAPGEQDIELLCAALSGAGDEDQLAVRS
GGLHGRRLVRANQPELPGTPWTPRGTALITGGTGALGAHAARWLAANGAEHLVLTSRSGS
AAPGASELTAELTALGAEVTIAACDVADRDAVADLLRSLPEPPAAIVHAAGIVAPETPLT
DLELTDFTAMFGAKVAGARHLDELTSGLDLDAFVLFSSGAGVWGNARQPGYAAANAYLDA
LAHRRQALGLPATAISWGAWAGGGMVDAQEAVRLRQRGVPAMAPELAVTAMEQAVRSGVP
HVVVADIDWTRFAPTYTLVRARPLLGDLPEVRALTEAEPAVAVAAEDDRTDFARTLAGLS
PAEQRRSLIDLVNSQAARVLGHSGTLAGTGRQTFRELGFDSVTAVDFRNRLGTVVGLRLP
ATLVFDFPTPAALAEQLLGTLVVPDHRPDDRDPLAELERFELGLTRTPPTGAERAELATR
LEALLRRWGAPAVADHSGEEPEDLLDTATDDEMFELIDNELGLA
>C7Q959|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Catenulispora acidiphila (strain DSM 44928 / JCM 14897 / NBRC 102108 / NRRL B-24433 / ID139908)|TrEMBL
MCHTPYPLVTLNQWPYGRAAQDGAAMPVARDRRELVVGIGPCGVPNARLAAAVERGGGTG
VVDLGTGGRTARDELALAAEWLPDGFGVRCGQDCGLEPAELAGIGLGRINLVVLGVDSPW
RAADLVHADPDPGYRILVEVTSVAEARAAATAGAHGLIARGSEAGGRIGELSTFVLLQRL
LAEPGLDSDLPIWAAGGIGDHTAAAAVVGGAAGVVLDTQLALLPEAELPEPIRAALRVMD
GSETVVVDGRRVLRTAASASHIPIGQDGFLANRFLKRHTDTAGAVRAMHAAIIEALCDAD
AAESLVPQGPLAATLGVRVPVAQGPMTRVSDQASFAATVAEDGALPFLALALATGEQTRT
MMEQTAAALGERPWGVGVLGFAPAEVRTAQLDIIKELRPACVIVAGGRPAQARALEDVGI
ATFLHTPSPGLLSQFLTAGARRFVFEGSECGGHTGPRASFPLWEAQLGVIEDWLAEQPQR
KAKDKGNANANTAEPANNLQILFAGGIHDARSAAMVAAMSRSAVAAGVQIGVLMGTAYLF
TEEAVTRGAIQPLFQRQAIAADATALLESAPGHTTRGIVSPFTTEFQNLRQQLHADDVPQ
REAWERLEQLNIGRLRIASKGLLREGMELVSIDEDRQLREGLFMAGQVAVLRDSVTTVAD
LHADVTEGACAFYATRHEEAVRTLGIRSEADDPVHELPAPLDIAIVGMACVFPGSPDLAA
FWATVLDGADRITEVPAERWDPDIFFDPDAVGSAAGRGTPSKWGGFLPPIPFDPLRYGIP
PNALSSIEPTQLLALEVARRALVDAGYDRPGVDHDRTSVVFGAEAGSDLSNAGVLRTTLP
TYLGTLPADLDDQLPRLTEDSFTGVLANVIAGRVANRLDLGGANFTVDAACASSLAAVDI
ACKELTLGTSDLVLCGGVDLHNGINDFLLFSSVHALSPTGRSRAFDADADGIALGEGAAC
VVLKRLADAERDGDRVYAVVKGVGSASDGRALGLTAPRPEGQRRALERSYRSAHVSPARV
GLVEAHGTGTVVGDRTELSTLTKLFTEAGAEPGGCALGSVKSQIGHTKCAAGLAGLVKTT
LAVHTGVRPPTVNITRPNPAWTAAESPFTFHAAASPWALPPGERIAGVSAFGFGGTNFHV
VLSGHERAVDPRHTRSEWPAELFVFRGADRDAAHRAIKTLMSRTAADASRTPWRLRDLAL
AAARAADARTDRAWVAIVASDLDDLATFADRALAGEHDPAEGLHQPPDTVYFGSGAAEPG
GTAFLFPGQGSQRPGMLADLFVAFPELQHYLRLGGEYADVLNPPRAFDDATAVNQDLRIR
DTRVAQPVLGIGGLAVDHLLRKLGIKPDAVGGHSYGELVALASAGALDPATLLDASRGRA
QAILAAAGDDPGAMAAVAAGSEEIAALLEQHGLADRVVPANQNSPKQVVISGPTAAVDEA
VSHLRAAGVGAKRIPVACAFHSPVVAAAGDSFGQLLAHMPVRAPETPVYANRTAAPYGPT
ADEVRAELSAQIGSPVRFVEQVEAMYSAGIRVFVEAGPGRVLTRLVDAILKDRPHVAVAC
EEQPGAGVRGLLTAVARLAVSGVELRTGWLFEGRDVQDAATATAAARPGWTVDGHLVRTA
DGACVPGGLAPARRISLEGSTLTPRSVPPADQDALLAEFLKTNREMIAAQRDVMLAYLGA
APAGRMVWQEAETPTPLAIPTVQQPIPAKVIEPATEPARTTDLLGTILEIISARTGYPSD
MIEPDLDLEAELSIDSIKRTEIAGELAERLGLAASQLEDDQLEELAKARTANAIAHWLRE
HLDDGPEPQAVTIAPASSGPDAAASALAPKRFIMREEEHSFGEPADTGALTNTRFAIIGA
SGSDPLAQTLSSRLADLGVTVEIGVDRVDAATGPDGIVHLGALSAGDGEESRLLPHGFAD
IKQALARSPRWFLAAAPLQDRSASAGLRGLWRTIDREYPQTTARLVELDRDASAEDLAAQ
LIEEIVRPDREPLILRRDGLRHRIAAVETPLGALASSGAGPAGDGAAEVQALGLDRDSVV
VLIGGARGITAHLAETLAATSRCRVELVGRTALPEGAEPAATASAADGPALRAALIAGGL
SAPAQIEREASRILAAREASATLARVGALGSAVRYHSLDVQNGEALHRLLKGIHAEHGRI
DAVFYAAGVIEDKLIADKDPESFARVFATKAEGARVLLSGLDDLPERPRYTVLFGSIAAV
FGNRGQCDYASANDALEALGADWSARTGAHCLTVHWGPWAPSAEHGGMVTPELAQSYGKR
GIALIDPEEGVLALLRELAWGDGAGSVVYSASQW
>A0A086QUJ3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii MAS|TrEMBL
MTEAATPQNVTSPADLSKQNVSFRPGVNAVEFVSGYSHAGSVVCSLPSPIFFNKASSSNG
NCESNASTASSSAALGTEASSNVRTGTVLIFDCGSGNTWQHLRQWLSDEGASHIVVVHAC
AEEGADTLGVKTLHPSRVNGGQGCSQTLIKEVKCRPHHPEEVVELFKLLKEGLHFPLVRG
IFYILGEKLDSLLANQTTSSVHDMMKTASGAWSIHHALGQLGMEADLDFFIFFSSISALF
GSISQSISAAVHASLDALAYYRRHLGLAATSIQWAPWADGSSATSPQIVRHWLEKGGVSS
VRNPLAAVSAILKNHTAIGAVVACFHADPTIMHEMGETDQECTFLSSGPAANTRDSTSGN
VKVRTNPVKSRVFQNVSPSTDTCGENHKDELLVILTQLVRREVIEIASCYVFFEGNNLST
DESLVDLGLDSLSAVELRHTLQQRFCVNIEPTFLQANATIDSISALLVTHVATSLTGALP
VLPLSCPGLASAVDDCALVSLALRLPGRCDSLDAFWASLQSDSGYCRPGASEACDQCFMH
RAGSGELPAESQSIGTNLDARKGFCWLSNRDAFDSHFFGISFTEALATDPCHRLLLEATY
EALCKLNTEQQSGTSGTPIAVFATSSSTQMRASLPSYTKPASSQNTQDNNGCLAASFLSY
HLNLTGLAVPIDGSDSASLIALDLGREHLRGTDSVCQAVVVAAGSLLPICSHGWPSACTS
PTIRRFRGRDDYAFPDRETYAVPRGEGIVSVVLQRLSVARENGNSPMAILKGISLIRMGR
GERPIPSQWRTADVKLRRKTIVEALKMSRIEPRTVAVLETDGLTGSQAEDAYTVEAMADI
FGPRHLAESCSPLVIGNASLHIGQAREASGLATLAKLVLMLERGYAPPIPRLRRLHPDVK
RGILPSGFVMFPCKKMDLLAFRQHPDHVYGPNEKRDQKEGRPLIGCVSSLGSDKTSGCFI
VESSPRRHGRTSDTRVSLERAVPLAGTKDACSHNYLHVRSTDGSESEIRGDDRAVWLFCD
DLWGLQSVGRGLYCSDPAFAALLEQAERVLGNRIPQPLSCLLYPSTTAEFQKAEDALAFP
RIAAFVLFSLQWALATCLRHQEGEPTAVMGLGVGEIAAAAVAGILSLEDAVELLELLSSE
TRTCDYRNKPMPGGNVNSGGLFDRGNSGTGGCGVAQDCKSPWVLCGLNKTPTSESAALEF
SVLESRRGSSSRISSETPTSNTTPHNRDVFQERFSRKPRRATCPSPIIRHAWEKVAHGNP
ENDEEAELECPSSQSRRANCPSPAIQHACEETAHGNHANDGEADLLMDVFRFRPEPSEPL
GQVTARIALRNATCLFISTVSGRLATDTLIRAAEYWDPLVPKTQRVHRAVETAVQVAKTA
KLVCIGCSAQDGVHLSVGLPSVHPISPSPLRIFCFTGSSPSPQLLAPCESASGSSPRVAV
VEHHGADSNLGGGAPWWKHLLFRLPQLEGFPSGCSASTRLLADRLVADVPTPDNHMINNP
QTAAVQGAGETLGTLREGSSGEGEDGEKGYRSESVNTQHPVYKVYRRCSEPELHESELSL
LCSDTVCQPSLEKTVELFIGTGLEQQGKLSTVSSSWLVFSDIVAPSPISLYSTLAFQNED
GEQRFCTLNVASQVATVYAEKVKTQVCSIIIECKRGFKPPREIARCHFVKNQTAVGKHEP
AVSSLSRIRWLPATKLPEGWLRTRRPHVWPCKIKVTKAACPLPTRRVDLQEIYWGKRHIL
CRFRMPRNPPRDGVEKSTQLIAILARLVTVSVGVAATCVLHETETSGRYSHSHPGPQVED
DQKTHMDALWVCPYVPFSECWCVIRHRRNGSSIKEGKGRDWETCDVEIFSENGTAVAVVL
GFGIQSHALSMRMMGGRGNDGDSSVSTTVCVA
>A0A286TAV0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Bifidobacterium bifidum LMG 13195|TrEMBL
MKAVFAATINNADPLAALEVGELPEPQPRPFWSTVSVKAATVNHHDIWSLKGVGLAADAT
PMILGTDAAGVLDEDIPVRKGLKAGDEVVLYTVIGADGAGVMPGERRTILSERYPGTMAS
KTQVPSANVFAKPANLTLDEAAALGTSWLTAYSLVFASAGVKPGDTILIQGAGGGVSTAA
VQLAHAAGLEVFVTSRDETKRERALALGADAAFEAGARLPRKVDAVIESVGAATWGHSVR
SVRPGGTIAICGATTGDQPGAELTRVFFQDIRVQGNTMGSREDFVRLLRFVEHADIHPVI
DSTFGLADARAAFAKVLSGDVFGKVVVRI
>G8SMA1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)|TrEMBL
MSIRFLPLSARSAATLTRLRERIADHLVAHPRVALDDVAATLSRGREPFRYRCVVVAGDR
DGTVAALRGERPTIRGAAPAGRAPRLVFRFGDGARDGFGRDAYDRLATVRRVIDDLDAAL
TERFGAPVRLLDAAAGGTPAAPGDRAAAVTVAVGYAIAEQLREWGVTADTCTGAGVGART
AAVLAGELDITTAVAQAWAGEPHSPAPGTAEPSPSGPDTQPAAPDVLSVEIGPRPGLSPA
GDIVVAVLPGEDEVAALAAAAAEVWCLGADVVLSAPGDRVHLPGYPFERAADADPRPAAA
QAVTNAWREVFGTSTPGTELGPLVTLRRAIAARWGYAPTLPQLAAAPDDRQVLADLTEIA
TAESGSTRRERPLTAREQRLVFHDAVRAGSSSAEHTVQLSIPLEREPDPDALDAALRDAQ
LARPLLRTVFRRRDDRWVAAEMPHPLVTLTRSAPGAEAADHAFQPVDAPLLHVALRPYDD
RTDLVVALHQALADHLDIHQLAAELLDTATTRSPS
>A0A0N1FZM4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MTSAARATDMIIGITPFAEPDARLAAAVCRAGGLGILDLGGGDRRSREALTRVRRLAPGA
FGVRVGAGCRMTPADIAADGGPHTVVLAVDAPFSAGDLVAAHRVLVEVTDLAQALDAVRA
GPHGLIARGSESGGRVGELSTFVLLQQVLNHPDVDLPVWAAGGIGPRSAAAVVAGGAAGV
VLDSQLALLAESRLPEAAAAVLRSMDGSETTLVAGHRVLHRRGPDAPQVPADPAAVSGML
GAHDLRTQLLPVGQDGFLAARFADRYGDTGRTVRALTEAIQDAVRDDTPARALAADSPMS
RALGTRLPLAQGPMTRVSDQARFAAAVAEDGALPFLALALATGEQTRLMLEETRTAVGER
PWGVGVLGFAPEDLRAAQLDAVRELRPSHAIIAGGRPAQAEALEQEGIRTFLHVPSPGLL
KQFLDAGSRRFIFEGSECGGHVGPRHSFPLWEAQLAVLEDFLDGADDATAASLEVFFAGG
VHDERSAAMIAALGAPLTARGAAVGVLMGTAYLFTREAVERGAIQPLFQRQVVDATATTL
LETAPGHATRCVPSAFTDGYRAHEARLRAEGAADRRVWEELEQLNVGRLRIASKGIERDS
ATGAPVPVGEERQLSDGMFMAGDVVVLRSATTTVEALHRSVTDGATAFLAAGAARLRTEL
GLAEPETAEAPRPLDIAVVGMACMFPGAPDVASFWANVLGGHDAVTEVPAERWDPAVHYD
EQGDGATTSKWGGFLPRIPFDPLSYGIPPASLGHIEPVQLLALEAARRALENAGYGDKGR
SFDRARTSVVFGAEAGSDLSNATTLRAVLPAYYGKVPDGVEEQLPGLTEDSFPGMLANVI
SGRVANRLDLGGANYTVDAACASSLAAVDVACKELVGGTSDVVLCGGADLHNGINDYVLF
SSVHALSPTGRSRAFDDSADGIALGEGVACVVLKRLADAERDGDRIYGVIKGVGSSSDGR
ALGLTAPRPEGQRLALQRAYRNAGVSPAEVGLVEAHGTGTVVGDRTELTILSEVFTEAGA
DVGGATLGSVKSQIGHTKCAAGLAGLIKTTLALHTGVKPPTLHIDRPNAAWQQDSSPFAF
HAEARPWAAPPAERIAGLSAFGFGGTNFHVVLEAYGDAVPPEQSLDAWPAELLLFRGKDP
AAIRRTVEDVLKAAEADGRPWRLRDLALSAARRADASHEPVQAAVVATEVDGLAGQLRRV
LAGEHDPAAGIHLARPEAADGKVAFLFPGQGSQRPGMLADVFIAFPELQYYLELGRAHAG
VLYPPTAFDEAARERQRAALTDTRAAQPALGITGLAAHALLTTAGVRPDMAAGHSYGELV
ALAAAGALAPETLLELSAERAEAILAATGGADPGTMAAVAAGAEDVAQALRTAGAPDTVV
LANHNSPKQTVISGPTEDVTTAVRLLREAGLGAKRIPVACAFHSPLVAGAGERFAAVLAE
KTVHAPEFTVWSNRTATPYTEDADAVRAELAAQIGAPVGFVAQIEAMYEAGARVFVEAGP
GTVLTRLVGQILGDRPHTTVACEPRANSGLAGWLDALAQLALAGQPVRTGRLLSGRDAVD
AVRTPAPKRPGWTVDGHLVRTAAGDLLPGALAPARRVVETTVTTNHPYGGPGDRDARIAE
FLRTSREMVSAQRDVLLTYLGGAPGQYIPAPAALGPVPQPQYAPVRAQYAAPAELAAPVE
QSAPEPVAAEPAAAVTEDDVQQVVLEIISERTGYPVDMIEPDLDLEADLSIDSIKRAEIA
GELAKRLGIAGDATALDDAELEELAKARTAASVTGWLTARITPATEDAPAAEQPEPQAAE
PEEAVPVAAAAAARPADEPPVTGEAPKRLQLQPVALAEPDASADPVAVLTGKRFVLLGDG
DGDSEGTARTVAARLAAHGALAQTLAASHELTDAEGPVDGVLYLGGLTAAGAPVLPDAFP
VVKAVLGRNPRWFLAVRPAAGDAAPDLKSAGLHGLFRTVVREYPDTVARIVGVDDTAPAA
VADALFAELLAPEPAPVVLRTAAGRHGLELVETPLGALATSGAGPAGEGAAEAAALGLDR
ESVVLLVGGARGITAKFAATLASASRCRIELLGRTPEPAGPEDAAVAAAGTPAELRAALA
RSGAGLKPAEVNRQAELILAQREIAATLAELTALGSEVRYRSVDFREQDAALQAVKEIHA
EHGRLDGVVYAAGVIEDRLIAEKTTESFQRVYGTKTSGATTLLAALAELPNGPGFAVLFG
SISAVLGNRGQVDYAAANDALESLGADWAARTGNRALTVHWGPWAPTGGHTGMVSPELGR
EYARRGIKLIDPEEGTAALLRELAWGDESVRAVTYTSSGW
>A0A0N0MM84|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MTRQADTHAVPAGHGTVAPGAVPAPVAVIGLACRLPGAPDPDSFWDLLRRGGHAIGAPPA
GRRAPGDAGEPRDADLPGGFIDDVDHFDADFFGVSPREAAEMDPQQRLVLELAWEALEEA
GTVPAELAGRTVGVYVGAMAYDYATLRHRPDAGPLTRHTLTGLSRGLLANRVSYTLGLRG
PSLTVDSAQSSALVSLHLAYRAVRDGDCELALAGGVNLNLAPDSTSAAARFGGLSPDGRS
FTFDARANGYVRGEGGAVVLLKPLAAALADGDRVHSVILGSAVNNDGASDGLTVPSADAQ
REVLLRAARDAGVDPREVQYVELHGTGTPVGDPVEAAALGAAYGTGRRGDQYLRVGSVKT
NIGHLEGAAGIAGLLKTVLGIRHRRLPATLNHETPNPRIPLDQLRLRVQRELGPWPRPDL
RLIAGVSSFGMGGTNCHVLLAEAPETTPRTTDVLPDALPDADSDTGTADAGQGTEAVIPW
PLSGATPAAPSAQAGRLADHVRARPGLAPGDVGHSLATTRTRFAHRAVLLGSDRASLLGA
LDALAAGAPTPGSVVGRAPARTAGPVAFLFPGQGSQRPGAGRQLHATAPAFTEALDEVCE
RFDHHLDRPLREVLFAAPGTPEAALLDRTQYTQAALFALGAALNRLLEHHLPAPDFVLGH
SVGGLTAAHVAGVLSLADAVTLVAARGRLMERARAGGAMIAVEATAAETEPVLADYVGRL
ALAAVNGPRAVVISGDVDAADEVAARFSGQGRRTRRLRVSHAFHSPHMDGAVAEFRRVAA
TLDLRPPTLTVISDVTGLPATADELTSPDYWAEHIRRPVLFHDGVRQLEARGVTGFAELG
PGNVLTALTRDSLDASPPPPAS
>A0A380N762|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces griseus|TrEMBL
MAVRSSAAFARRLVPAPPAEPDAGWQPRGTVLVTGGTGGRGAHVARWLAGAGAEHLVCSA
ARPGAPGADALRAELEATGARVTLVACDAADRDALAGVLDGIPADTPLSAVVHAAGVVDD
GVLDDLTPERFAALHHARTVPAVHLDELTRGLDLDVFASAPPSPAPSARRAGPTRRRHRR
PRRPCPAPPERGAARTSMAWGAWIGDAEEAGAKDAPDSRRTGAGHPAVHPDLALAALRRP
>A0A1V2RTM4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MTGTEANVVAALRASVKETEKLRRQNRELAEAAREPIAIVAMSCRFPGGVESPEDLWRLL
ESGEDALSLFPDDRGWDLTAPADGEPVDGEPSGGAARSGGFLRDAGAFDPGFFGISPREA
LAMDPQQRLLLETSWEAFERAGIMPDALRGSSTGVFMGTNGQDYAALFPGAAGGAEGFLI
TGTAASVVSGRLAYTYGLQGPAVTVDTACSASLVTLHLAVQALRGGECTMALAGGATVMA
TPTAFVEFSRQRGLAADGRCKAFAEAADGTGWGEGVGVLLLERLSDARRNGHPVLAVVRG
SAVNQDGASNGLTAPSGPAQQRVIRAALDSAGLGPADVDAVEAHGTGTTLGDPIEAQALL
ATYGRDRDAERPLWIGSVKSNIGHTQAAAGVAGVIKMVQALRNGVLPRTLHVDRPTPAVD
WSSGAVRVLTEPVPWAGPGGRPRRAGVSSFGVSGTNAHVLLEQAQDAEPEPGTTGEQDGP
ARPLVFPLSARSAAALRGQAERLGAHLRERPGARLADIAHSLAGTREPMEHRAALVADGR
DGLLAACAALAAGDPAPGAWTGRARRGRLAFLYTGQGSQRPGMGAALAGAFPAYAEALDE
VAAHIDPLLGRSLRDLLAAEPGTPQAEALHGTDLAQPALFALEIALSRLLATWGVRPDAV
LGHSVGELAAAHVAGLLTLPDACALVVARGRLMAAAPGGGAMAAIEASEPEIEPFLSGNA
DLVSLAAVNGPSAVVISGDADEVARIAAAWRDRGRRTKDLKVSHAFHSPHLAGVLDDFRA
VADGVTYHRPTVPVVSNVTGALADFAEIGTPDYWVRHMRGTVRFADGVAALLGHGVSACL
EVGPDGVLTGMGQGCVPADADTRFLPTLRADGDPVTDVTTAVARLHTVGRQPDWEAFHAG
LAPRRVDLPTYAFARERYWLDAGPVAGPATGPAPAASAAQAGDEAPGDPLGGLVPEERQA
AALDLIRRHVAAVLGHADPGAVEPDVAFSDMGFTSLTAVELRNSLVAATGVDLPASLVFD
HPTARAAAAHLAAEAAGTSGAARAARLRAAAAARSRADEPIAIVGMGCRYPGGVRSPEDL
WQLLAAGGDGITPFPDDRGWDLDGIYHPDPDHPGTTNGREGGFIDGADLFDAAFFGINPR
EALAMDPQQRQLLEVAWEALERAGIDPSALRGSDAGVFVGAATQDYGSDTAELPDGVETY
LMTGNTGSVISGRLSYTFGLEGPSLTVDTACSSSLTALHLAARALREGECSLALAGGVMV
MPSPTPFVALAKQRGLAEDGRCKPFDAAADGTGFSEGVGMLVVERLGDARRNGHQVLAVV
RGSAVNSDGASNGLTAPNGPSQERVIAAALADAGLAPADVDAVEAHGTGTRLGDPIEAQA
VIATYGQDRDAERPLWLGSIKSNIGHSQAAAGVAGIIKMVEAMRHGTLPATLHLKEPTPH
VDWSRGAVALLAEATPWPDSPGRPRRAGVSSFGVSGTNAHVLLEEPAPEDRPGGPGTDDG
IGEEAEESEAAAGPGPFVALPVSARTGTALRARAAGLARHLTRERTGRPVDVAHSLATGR
AALTRRAAVLGRDRAGLAEALTALAEDRPHPSVVTGQAAADAARPVFVFPGQGSQWTGMA
MELLDGAPAFAERLAECQQALDPYIDWSLTAAIRGEPDAPSMERLDVVQPALFAVMVSLD
ALWRAHGVRPAAVLGHSQGEIAAACSVGALTLQEAARLAALRSRAYQRLAGTGAMGSVLM
PHEEVEPHLERWAGRVSVAAVNSPGSTVVSGDPAAVEGLLAELGDAGVKVRRIAATAAGH
SAHIEALRFDIDTAAGGIEPRPSDVAFCSSVTGDLTGTEELDAAYWFANLRRTVRFDRAA
RTLMAAGHRAFIELSPHPVLTLSLQETAASLGRDIVALGSLRRDEGGTERFLTSLAEAHV
HGVGVDLAAAAPGGRRVALPTQPWEGSRYWLTPGRGAGDLAAAGAEGEPHPLLGAHVALP
DGGLVLTGRLAVNDVPWLADHAVAGTVLVPGAGLLELALRAGAATGAARVAELTLHTPLV
LPERGGVQLRLVVDPPGPGGRRALGIHTRQADDEPWLRHADGLLAPATGDAPADGVFAAW
PPEGAEAVGLDGAYERLAEAGYDYGPAFQGLAAVWRRGEDTFAEVRLAERERTEAERYGL
HPAALDAALHAAAAGRADTAVRLPFSWAGVDLHAVGAATLRVHLTARGGDAMAVRIADGA
GRPVLTADALVTRPVDVDAVKRAGERTDAAHTWLYETAWTPLAAAAPPASAPGRWAALGG
IAAAEGLQAVGVPVDAYHDLAELAAAVAAGTPAPELVLALADGAAPGPDETGETGETGEE
LALRTHEAARRTLALVRDWLTAPGLAAARLTLLTRGADADPAAGALWGLVRSAQSENPGR
LTLLDVAGADEEVPWRDVAAALAVADEAQLSIRSGAVHVPRLAPAPGAADASGDATPAPL
PGTALITGGTGTLGRLVARHLVTRHGTTHLLLASRSGERADGAAEFAAEMEKLGAAVTTV
ACDVADRDALARLLADVPAEHPLTTVVHAAGALDDGLAVSLTDEQLGRVLRPKADAAAHL
DELTADLDLKAFVLFSSASGTFGGLGQANYAAANAFLDVLAARRRAAGRAAVSLAWGTWA
PASTMTALTETDLRRMARGGIVPLTAEQGLALLDTALAMQDRPALVPVRLDLDALGAQAE
AAGVPVPGLFRGLVRPAVRRAAQHAADPGAGQRLAALPDAERLAALRELVREQTATVLGH
GAADAVDAEAGFGELGFDSLTAVELRNRLGTATGLTLPPTLVFDHPTPADLARRLHTELG
EAAAAPAAAPGVANGGPAGGGSLLPLFADAVERGEIREFVGAMNALSRFRPAFDDAPGDA
AGVRLAGGDEGPLLLCLPPVIGISGPHQYARFAAALRGRRTVVALPHPGFRTGEPVAATA
RALARAHAATALRLAAGAPFVVVGYSSGGFVAHAVAEELQAAGTAPAGVVLLDSYPPDET
QLLERLIPAVVRGIQDRKDRMLGGEDDAWLTAMGRYMGFDWTPSPVAAPTLLVRSGEPLP
GLPENEPWRATWKHPHDAVDVPGDHFTMMEEHAAAAAAAVEEWLAR
>A0A1V2RUK0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MANEDKLREHLRWATAELTATRRRVRELEEADREPVAVIGMACRLPGGVSTPDDLWRLVA
DGTDAIGEPPADRGWPDAFYDPDGERPGTSYVRVGGYIDGADRFDAAFFDISPREALAMD
PQQRLLLETSWEAMERAGIDPASVRGERVGVYAGLMYHEYAARLSSVPEPVAGFLGAGNA
GSVASGRIAYALGLEGPAVTVDTACSSSLVALHLAAGALRRGDCTMALAGGVTVMVTPSG
LIEFSRQRGLARDGRCKSFAAAADGTGWGEGVGMLLLERLSDARRNGHPVLAVVRGSAVN
QDGASSGLSAPNGPSQARVIRQALDDAGLAPDLVDAVEAHGTGTSLGDPIEAQALLAAYG
RDRPEGRPLWLGSVKSNIGHTQAAAGAAGVIKMVLAMRHGVLPRTLHVDEPTPHVDWSSG
AVELLTRAREWPDTGRPRRAAVSSFGVSGTNAHVILEQAPPEEPAAPPGPERGAVPWVVS
ARSAAALDAQVARLRAAVQAHPEWDPADVGWSLAAGRSPFEHRVVAVGADRAELLGALDA
PAGGSRPRLPVFVFPGQGSQWPGMAVELLDHSRVFREALTACADALAPFTDWSLIDVLRG
RGELSRVDVVQPALFAVMVALAAQWRSLGVEPSAVAGHSQGEIAAACVAGALSLDDAARV
VALRSLALKDITGDGGMASVPLSREETEAGIERWGGRLSVAALNGPRSTVVSGDRDAVEE
LVAADLGARRIPVDYASHSPHVERLRQRILNDLSGIAPRAGAVPFHSTVTGGLLDTTGLD
AAYWYRNLRQPVRFDTVVRDLADRVFVECSPHPVLTVGIEDAAAVGSLRRDEGGPRRFLT
SAGEAWANGVFVDWRRAFTGRRRVDLPTYAFRRRRYWLEDTGAAAADAASLGLRPAPHPL
LRAAVPLAGDDALVLTGRLSTATHPWLTGHRVFGSLPVPGVALAELAVHAGDHAGCDLVE
ELTLRTPLVVPEAGGVQLQAAVGAPDAHGRRELTLYARPDDAADAPWTRHATGVLAVAAR
RPEAERDPRPAWAPAVWPPEGAEPVPVDGLYERLAADGLDYGPGFRGLRAVWRRGAEIYA
EIRLPDGHEGHDGQDGQGERGVGAEGFGLHPALFDAALHAAALSHPGRVALPFSFTGVAL
HATGATALRARLTPAGRDAVEVAVADTSGAPVATVASLASRPVARDQLTAARGPLWHVDW
APAALPDDPPAERWAVADEDSLGLGADRWDPAAEVPAPDVLFLPFLPPPPPPPPPPPPPP
GAGTVAEAACGATHRALAVVRDRLADERLAGTRLVVVTRGAVAAAPGEPVHDLVHAAVVG
LVRSAQTENPGRITLLDLDPAARPAPRELLARALAADEPQLAVRGAEVLVPRLARGDARR
VLQPPPDGDPWRLDVTSKGTLENIALLPAPAADEPLKPGQVRIAVRSAGVNFRDVLLALG
MVDQDVMGGEVGGVVLQTGPGVTGFAPGDRVIGMVPASFGPVAVADERLITLLPDGWSFT
EGATVPIAFLTAFHGLVDLAAVRPGDRVLVHAATGGVGMAAVQLARHLGAEVYATAGPAK
WDTLRAMGIPGERIASSRDLGFEERFRAGTGGRGVDVVLNSLAQEYVDASLRLLAPGGRF
VEMGKTDIRDAAEVMAKHPRISYEAFDLIDAGPERIGRMLADLKDLFARGVLAPLPVATW
DVRAAPDAFRFIGQARHVGKVVLTVPPGRPDPQGTVLVTGGTGVLGTLVARELVAVHGVR
HLLLTSRQGADAPGAKQLVDELAALGARVTVAACDASDRDELAAALRGIPAAHPLTGVIH
AAGVLDDGVLAALTPRQVDAVLRPKIRAAWHLHELTAAADLRMFVLFSSATATLGGAGQA
NYAAANAFLDALAAHRRARGLPGLSVGWGLWARASGMTGHLDAGDLTRMRRAGVTPLSDE
EGLALFAASLAAERPHLLALRLDPAALPGPVPALLRDLVGAPARRAAGAVGDGQGEQALA
ARLAPLTGAERDGLLLDVVCTHAATVLGHAAPDDIRTGQAFRALGFDSLTAVELRNRLNT
VTGLRLAATVVFDHPTPAALAAHLRSRLTPDPAPGRPAQEEDRVRSALAAIPLTRLRQAG
LVDTLLELAGHDRDRDPGPGSGGDGDGARGPHDIDAMDADALIGMALDTTDL
>A0A1V2RR24|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MSEQSRAAMLELVLTQAAAVLRSIDPDAYPDGATDVAADRPFLAVGLDSLGLVQLHRRLG
DELGVDLPVTAAFDHPTPAALARHLVNVLHGTAGPDEPAEPAGFAAPAAQAAPDEPIAIV
GIGCRYPGGVTSPEDLWRILADGSHAITDFPADRGWDLDRLFGRDPAATGTTYARRGGFL
PDAADFDADFFQISPREALAMDPQQRLLLETCWEALERAGIDPDRLHGTPSGVFIGVEPH
EYGPRAHEAPDGLDAYVLMGNLPSVLSGRVAYTLGLEGPTLTVDTACSGSLTALHLAVRS
LQRGECGLALAGGVTVISSPGTFTAFAQQRGLAPDGRVKAFAAAADGTSFAEGAGVFVLA
RLSDALRDGHQVLAVVRGSAINQDGASNGLTAPNGLAQQRVIRQALADAGLAPDEVDAVD
GHGTGTTLGDPIEGQAVLAAYGRGRPAEQPLWLGSVKSNIGHTGAAAGAAGVIKMVMAMR
NGTLPRTLHVDEPTPHVDWSQGTVRLVTEPVPWAAGDRPRRAGISSFGASGTNAHVIIEE
PPALPAAAPPDPADDRPVPVVLSARTQDALRAQAGRLLATAADAAPLDLAYSAATTRAAL
HERAAVVAADRGELHRALTALAEGATAPGLLTGTKQATGRTAFLFTGQGSQRPGMGRELV
VKFPVFAEALQEAADHLDLHLEQPLGDVLFAEPGSPAAELLHRTQYAQAALFAVETALFR
LLASWGVTPDLLAGHSIGEIAAAHAAGAMSLADAALLVGARGRLMAELPAGGAMIAVQAE
EAEVAARLTGQLTERVSIAAVNGPSAVVLSGEADAVSDLAAHFAGQGRKTRRLHVSHAFH
SPLMDPMLDEFRRVAQSLTYAPPRIPVVSNLTGEPVTAFDADYWVRHVRRPVRFADGVRW
LEAQGATTFLELGPDAVLSAAGRDCLAAPDADIAFAPLLRDGHGAERQALTALGQAHARG
VAVDWERFFAGRGARRIDLPTYAFQRKRYWLDAGTAPGTIGHPLLDTAVSLAGADGLVLT
GRLSTRSQPWLADHVIAGTVLVPGTAMVELAVRAGDEAGCGVLDELTLQAPLPLPADEEV
EIQVAVGPPDATARRSVDIHARPARSEGNWTRHASGLLAEGAEGAEGRAAAAPASTAWPP
PGAEAIDVDDFYERQAAQGYAYGPAFRRVRAAWRRGAEVFAEVATDDAAAGRFGLHPALL
DASLHAVESPEDDGQVRLPFAWLGVELHAAGATAVRAHVAPAGQDAVSIHLTDATGAPVA
DVRSLVQRPVPLDGLPSQRRRAGALLRIEWTGIQAPPEPDAAAGDFDLVFVPATFPGAPA
EAARAATLHVLELIRNALRDDTRPAFVTRNAAGDLALAPVEALVRAAQAENPGRFALIDT
DRDVPDSELRAALATHEPQLALRDGVLRVPRLARVPEPDERNEPDERNGRDEPRAAAWHP
DGTVLITGGTGGLGGHLARHLVRRHGVKHLLLAGRRGPDGPGAAELAAELRDLGAEATVA
ACDIADRTAVAALLDSVPERHPLTAIVHAAGVVDDGLTATLTPEQVRTVFRGKADGAWHL
HELTLELPLAAFVLFSSAAGTLGAAGQGNYAAANAFLDALAGHRAAHGLPATSLAWNLWA
GDAGMGARLDEVTLRRTARSGLPALSAEDNLALFDQALTTDAPALLPLHIDGPALRARPE
GVPPLLRGLVRAPARRHAAAAAAAAAGGALADQLAGKPEAERERFVLDLVRAQIAAVLGH
DSPTAVDPRRAFTELGFDSLAAVELRNALGSATGLRLTSTLIFDHPTPQALAEHVLDKAR
GAAPAASRPPATVRATADEPIAIVSMACRFPGGVTTPEELWRLVADSTDAITPFPDNRGW
PTDEIYDPEPGKHGTTYTREGGFLHDAADFDPTFFGISPNEAQIVDPQQRLLLEVAWEAI
ERGGIDPLSLKGSPTGVFAGIMYHDWAPRSGEVPEDLAGYTASGGMGSVASGRVSYTLGL
EGPAVTVDTACSSSLVALHWAAQALRQGECSLALAGGVTVMSTPETFIEMSLAQGLAADG
RCKPYGAAADGTGWAEGAGLLLLERLSDARRAGHPVLAVIRGSAINQDGASNGLTAPNGP
SQQRVMRQALAVAGLTPADVDAVEGHGTGTTLGDPIEAQALMATYGQDRPDGEPLWLGSI
KSNLGHTQAAAGVAGLIKMVMAMRNGVLPATLHAGTPSPHIDWSEGAVELLTEPRKWAPD
GRPRRAGVSSFGVSGTNAHVIVEEAPPAAPRQPRGARPPAVPLTVSAASPEALRAQAARI
AAHLRDHDDVDALDAAASLVRGRAALQHRAVVVHTDRADLLTGLDALAAGDTLASVIAGE
ARGDTRAVFVFPGQGSQWPGMGVDLLEHSPAFATRLGECAKALEPWVEWDLLDVLRGTPG
APPLDSDDTVQPALWAVNVSLAEAWRAAGIEPAAVVGHSQGEMAAACVVGALSLADGARV
VARRGQIVRQELRGRGGMLSVALSAERAEEHLADWGGRLQLGAVNGPRSVVACGDLDALA
ELRARLDAEGVQTRRVPIDYASHSAIVEDIRDRLLTELAGLTPQTSSVPFYSTVTAGQLD
TAGLDAEYWYTNLRRTVRFEETTRALLADGFGIFVETSPHPGMLIGIGETAEQAGVPAAL
VGTLRRNSGGPRDYLTSLAEAYVRGAAVDWQTFFAGTGADHVDLPTYPFQRQSYWLRVPA
RTGDASDVGQVATGHPLLGAAVPVAGDGGVLLTGRLSAAAQPWLADHVIAGTAVLPGAGL
VELAVRAGDEVGRGRVAELTLEAPLALPERGGVAVQVVVGPDLRTVTIHSRPEDAPVDGA
WTRHAHGTLADARPEPAPAPWLPPGAEPIDLTGFYERAPGDGSLTYGPAFQGMRAAWRSG
DDDVFAEIVLPEPTAAEAPRYGLHPAALDAALHATALLGTDAEQVTLPFAWTGIDLHASG
AAALRLRMTRLGDGEVALRLTDTDGRPVASVESLVLRPAAPGLPAPTAASHQSLFELRWT
PAQQDGQAPETVVHRCAGGHTAQAVHAETAAALNAVQSWLAADRTDGAKLAVATRGAVSV
NGEDITDLAGAAVWGLVRSAQTENPGQIVLIDLDPAEAGAETDEERLAQAMATTEPQIAI
RSGTAHRARIARVAGARTGAPATVFGGRPGTVLITGGTGALGGLVARHLVTTHQVTDLLL
TSRRGPAAAKAAALAGELAGLGARIEVISCDAADRDALADALAGRTLAGVVHTAGVLDDG
IVSSLTPEKTAAVLRPKVDAALNLHELTADQELTAFVLFSSAAGVTGGAGQANYAAANTF
LDGLAAHRRARGLPAQSLAWGLWEESSGMTGVLDAAALSGMQRDGAVPLPTGEALELLDT
AGTLDLPLVVPVRIDLTGKRRDDVPHLMRDLVMRGPARRSVEAAAPATESADSLRDRLTR
LKPARREQVLLDIVRTQAAATLGYAGPAEVDAERSFRDMGFDSLAAVRLRNSLGEAVGER
LPATLVFDHPSASALARYLLEELGLGEPKPAEEDEDTRGNEDFESREAEIQSMSLADLLR
AAQRSGDPT
>A8L4B2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. (strain EAN1pec)|TrEMBL
MTVPLDRLVEALRAAMKENERLRGLIAQAGEPIAVIGMACRFPGGVRSPDDLWRFVAGGG
DAITPFPTDRGWDTSALTCFGGGFLHDAADFDPEFFGMSENEALATDPQQRLLLETSWEA
FEHAGIDPRSARGSRTGVYFGVIFHDYGYRLRPPPPGIDGYAYFGSAGSIASGRVSYTLG
LEGPCVTLDAACASSLVGLHLAGQALRRGECSLALVGGVSVLATPELWEETTRHGQGLAP
DSRCKSFAAAADGTGISEGVGVLLVERLGDARRNGHPVLAVVRGSAVEQSGATNGFTAPS
SASQERLISRALADAGLAPADVDAVEGHGTGTPVGDPIELAALLATYGRGRPAGRPLWLG
SLKSNLGHTQAAGGAGAVIKMAMAMRHGVLPRTVHVDAPTPHADWSEGAVVLLTEAVPWP
DTAGRPRRVGVSSFGANGTLAHVILEQDQPPPADAAAGDGTAGDAVDRPVVPWPLSARSA
PALRAQARRLLDLVTERADLRPADVGFSLATGRSAFAHRAVLVADDRAEFLRGLTALAAG
PPESTDAALDGRTGAGLVLVLPGGGEWGLEAGRALADAFPAFAAEWATLRGALTGAALQT
APQVALQVALCRLLESWDVRPDAVVGHGAGEAAAAYVRGALSLDDLRALLAAGPRNASPG
CRVPPGTANALVVGRDAAGVDIPRGVRSWVLLPPGRTEIRAVTEASATLYEWGQAVDWRA
FFAGTGARRIDLPTYAFQRRRYWLEAADPGPTPAPGLPAAPGVRR
>A0A3E2YM22|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MW-13|TrEMBL
MSDDKLRYFLKRVTADLHDTKRRLQTVEARDQEPLAIVSMSCRFPGGVRSPEDLWELVAD
GRDALTEFPGDRGWDLEALYDPDPNKPGKSYTRVGGFLDGAGDFDPTLFGISPREALAMD
PQQRLLLETSWEAVERAGIDPLSLRGSSTGVFVGLSTSNYGIGLPHVPEGVDMYLGTGNT
TSVASGRISFTLGLNGPAVTVDTACSSSLVALHLAVNALRRGECDLAIAGGVTVMATPGV
FVVFSRQRGMSVDGRCKAFADGADGTGWGEGGGVLVVERLADAERNGHPVLAVIRGSALN
QDGASNGLTAPNGPSQQRVIRQALANARLGAADVDMVEAHGTGTTLGDPIEAQALIATYG
QDRPADRPLWLGSVKSNIGHTQSAAGVAGMVKMVMALRNGVMPETLHIDAPSQHVDWTAG
AVSLLTESKPWPELDRPRRGGVSSFGVSGTNAHVILEEYRPRVAGQDTVDGEGAVEATAV
EPAHRPGLIASDATVWPVSARSKAALAGQAARLARHVREHGDLAPAAVGWSLATTRSTFD
HRAAVVGTAAGELLAGLDALAAGQPAGNLVTGTVTGSGAGPVFVFPGQGAQSARMAAGLV
GRSPVFDARLAECQRALAPHLDVDLVAVLTGDDESWLDRVEVVQPVLWAVGIALAAVWRA
AGVVPDAVVGHSQGEIGAACVAGILTLDDAAKTVALRSRALAVLRGTGTMASVDLSADAV
TARLAAFPGVGVAAVNGPATVVVSGPPQPVADLVEACQAEGVRARLIPVDYASHSASVQE
VAEQLRTDLADVSPQAGHTRLVSTLTGDWADPASMTADYWYDNLRRTVQFDAAVRVAIAA
GHSTFVEISPHPVLTMPVTAILDDTGTTGHTLGSLRRGDDDATRLLTNLATAHAVGLPVD
LANVLAETGLAPLPTYAFDHQRFWLDGSGGPDLESLLQQAAADPSDASFWAAVERGDLTA
LAETIATEDTPADQALDALLPALPLLTSWRRQRRRQSDIDGWRYQDTWKPLTGVANRGMT
GTWVVVLPTGDIVEPWQDACVEAFTAAGATLVPVPVSTADVDRDLLGKLLREALAAAPGG
DGGAAEVAGVVSLLAFDELIHPLYPSVPGGFAATVALFQALGDVGLRAPMWSVTSGAASV
GRADLLRSPVQSLVWGFGRVAALEHPQRWGGLVDLPEAVDERSAGLLVAALTTAGEEDQI
AVRPGGVLARRLTRVPLGDSQPANPWQPFGTALVTGGTGALGGHAARWLARSGVENIVVV
SRRGMAAPGARQLVDDLTELGAQATVVGCDASDRDALADLIDAIPAEYPLTTVVHASAVL
DDAMINDIRPEQIERVLQAKVDVAYNLHELTLDLDLSAFIMFSSFAGSVASSGVGNYAPS
NAFLDALAQHRRGLGLPATSIAWGAWAGGGMADGPLGELLHRHGVPEMTPEAAIAALHQA
VDHGEAFLTIADIAWERFAVAFTATRPGPLIGDLPDVRRLATAETVAGVAAGDGPDTLQD
RLAGLPAAERLAVLLGLVRSQVAAVLNYASAESVDEHRAFRELGFDSVTAVELRNRLGTA
TGVALPVTLVFDYPTPTTLAEYLFAEVAHDDVVTPTALLDDLDRIADSLDVVARDEAARV
RATVRLQAMLSRLGQDSGGADIGRHLDDATDDELFAMVDKDLGIS
>A0A3E2YME8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MW-13|TrEMBL
MSVSLDEVVSALRASLLDNQKLKQQNQQLAAALSEPVAIIGMSCRFPGGVRSPEQLWDLV
AAGADAMAPFPDDRGWNLDALYDTDPDSRGTSYVREGGFLYSAGDFDPAFFGISPREALA
MDPQQRLLLEAAWEAFERAGIDPTTLRGAPTGVYAATSSQGDYAALLSGVGGGVEGYLGT
GSAAAVASGRISYALGLEGPAVTVDTACSSSLVALHLACQALRLGECTLALAGGVSVMAT
PTVFVEFSRQRGLSTDGRCKSFAAAADGTGWSEGVGMLLVERLSDARRNGHRVLAVVRGS
AVNQDGASSGLTAPNGPSQRRVIRQALANAGLTADQVDVVEAHGTGTTLGDPIEAQALLA
TYGQGRPADRPLLLGSVKSNIGHTQAAAGVAGIIKMVHAMRHGTLPPTLHVDRPTPHVDW
SAGAVSLLTEATPWPATGQPRRAGVSAFGVSGTNAHTIIEEPDPADVPPPVPAGTPAPPA
PWIVSARSAPALAGQAGRLLEHLAAHPDLAPADVAYSLVTTRAALPHRAAVTGADADALR
AGLRAVAEDRPAAGVTRGVARPAGKLAFLFTGQGAQRPGMGAELHRRFPVFAAAFDEVAA
ELDRHLARPLREVVFADPGSPEAALLDRTEFTQPALFAYEVAAYRLVTAWGLRPQQLLGH
SVGELAAAHVAGVLSLADAATLVAARGRLMQALPDGGAMLAVRASEAEVAPLLDDRVALA
AVNGPASVVLSGDADAVLAAGERLAAQGRRTRRLRVSHAFHSARMDAMLADFRVVAEKVT
WHPPRLPVVSDRTGDTLTAEQATDPGYWVDHVRDTVRFHDGVTTLAIAGVGTFLELGPDA
ALTALGRECLPDADAAAFVPVARRDQPEAAGLLAALAAVDLRGAAVDWPALFTGTDAARV
DLPTYAFHHERYWPEPPGFRLAPPPAEDAVDGDFWAAVEADEPAALAAVLGLDGDRSAAL
AELLPVLGAYRGRQRRRTELDGLRYRAGWARIAPPAAPAPPAGPCLVVAPTGADPDAVLA
ALRAEGLSPVLVPVGDDPGDLVLPAGDAPSAVVSLLAAGGSAGTAALAGTAALVRALGAA
DLGAPVWCVTRGAVAVDPDDPAPDVAGAYVWGLGRVLALEMPRLWGGLVDLPAAPDDAAL
AALARLVAAGGDEDQLAVRPAGVYARRLEPAPTGPAAADEDWRPRGAVLVDGAAGARGPH
VLRWLADRGAPHLLLTGAALPAEAAAELTARGVEVTPIGEPAELPDLLDRLAAAGHPVRT
VVHVADAGGAGEPVAGLDPAELAAAVAARVAAVELLDSACADRPVDEFVVFTSTAATWGG
GGAAVTAAVGAGLEALAARRRAAGRPATVLAWVPWADEVAEPGQLRRRGVRPLDAELAVA
ALQQAVGRGDDQLAVADIDWPAFVPAFTAVRPSPLLRGVPEATAAAAADGPAGGDAGDPA
RELLTRLTGSTAADRQRILLDLVRARVATVLGHASPGAIEADRDFLELGFDSLTALELRD
ALRQETGAELSATLLFDHPTPTALARHLLGQLLGAGAAGDAGEGAGEGGGGLLGGLFSQP
KARADSAGYAELLVKLAQFRPSFTDPGQLSRPAGILRLAEGGAGAPLVLCCTMSLLSGAH
EYARLASGFRGLRDVWALPNPGFGVGEELPADLAALLRVHADTVLRVVGDGPYVLGGHSG
GAMVANVLARELDRQGRPPAAVMLMDTYPADSEVLGGWVPELLDGMTDRDSAYTPMDDWR
TTAWAGYLPLFLDWQPAPMTSATLLVRASEPLGQWTGEPDGWRSRWPYPHETVDAVGDHF
SMVADRGPELAATLQGWLTGRDL
>A0A1X7AFQ9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Parendozoicomonas haliclonae|TrEMBL
MQYAIGGIAALLPGDEDRSDQALNNRSKWNCLSNSNIYSVDRCIRDCPPNRIPDHLSDKD
MFQLWSQYGKRAGWLENYDHFDAGFFQLSDAEATGMDPRQRLMLQTAYHALEQSGLTNTA
LTDCKTGVFVGASQDDFSCCLAGSKEQQPFLNPDAKPVTGDNRAMLAGRIAHALNLSGMA
CVVDTASSSGLSALALACRSLQAGECDQALVGSVQLNLDPLYTCRLGLAGMLSPKGRCAS
FSTQADGYVRAEGCIALVLMPLERALAEKRPINGIIRGLATNHDGRTKIPTSPDQAAQQA
VIQQALTDAGCLPEDIGYLETHGSGTPVGDPIELAALQQVFSHSEAARGHALPLGAVKAQ
IGHTEAVAGLAGLVHALAVLKSHERPASALDASHSLLAGGDYPGLQLSQTPIVWGAGNKL
AGVSAFGISGTNVHVIVEAAQSESDTVVPSQAPAQDKDDNEILLPVSAKTPEALKQQLDN
IQHWLLQNPTISLQDVMYTLAVGRESFDCRVLITGRNREELLEQLSRYQNPQLLHPPHDV
PAVKDQRSNSLQALAANWRDGHSVDWTLALDSGRIVSLPGYPFQTRAFPTPSLQRRPSEQ
QWQAPILLSHDEISANVLTICASVLGIDRNDLKPDIALRDQGLSSILTQVLHQKLESLCA
GTLPKTLLFNYQTPAAVIGYLQKTGVSPSTKETNQQVKDERIAIVGIGCRFPGSINNPEQ
FWELLISGKDGIEPLTNQRWAASFNRELPQGAGLLDDISHFDAAAFGIPESALEEMDPQM
AVLFQVVQQALTDAGLTRDQLRGSRTGVFIGISSNEHLSRRMQGDITANTLLFTAHSAMV
GRLSYWLDLHGPNLAIDTACSSSLVAIHKACQSLRAGECDLAIAGGVNLLLDPATTFYYQ
KLGVLSPTSRCRTFSTEADGYVRAEGSGIVILTRCNNAGVETALHTQAPRGFIAGSAVNH
DGYSQGMTAPNGLAQQAVIHSALQQAGCGAGDIGYAEAHGTGTALGDPVEVEALNAVYGQ
GRDADRPLLLGAVKSNIGHTESAAGVAGLIKVVLALEHGELPANLNSQPLSSAIPWEELS
LKVVSENQPGPASRWACVSSFGFSGTNAHAIIQRASIEEGQSQAIVRPYSPPVVTASDAV
PELGWKPLGVSFDSHPPSLYNLSWELCGEAGPWPSEMDLSISEENDHLVIWTLSGTRDTA
RQQVMAAIDKALAMLQMAIKRQEPSQPLVWLLTEDDNEASRLMVAALQGLSRVFVAEHSE
QSFYCITVAHNQGAIEACLKDRPAESVVIWKENGFHGLRLRSASPEFGLETQQRKLIIQQ
PGQLGGFGITSSPRQSPEAGEVEIAVRCAGLNFRDVMNILGLYPGEAGEPGLEVSGTVSR
VGEGCQRLKSGDAVYGLAPGGFSQYTTTNEQYLCRKGEWLDYSQAAGIPVVWLTAWHALV
TLGNLQAGETVLIHCAAGGVGMAAVQIARFRGARVIATASARKWDALREMGVEHLFSSRD
TGFYQGIRELFPDNGESGVDLILNSLTGDILDRSLDLLTAQGTFIELGKVDIRSAEWLAE
HYPEISYHHFDLMSVAAANPDHITATLQHLNGLFEQKVFQPLPVQTFPLSDSEKALRFMA
GAHHIGKLVLENDLGSSRSSIQTTSEPIALSPHAEEIIVISGGTGAMGIHLAGWLRTQVS
ATLLLVGRKPLTSKQQSLLGQWQTDADRKSDSKAATKASVRFWQGDISSPEIADALCDEI
RPQGRVIAVYHLAGVIEDCALIKANPEQFERVMAGKVWGAWNLHHRLVRYWPAANLVLFS
SVSGLFGIPGQGSYVTANASLEGLANLRRAQSLPVQIIYWGHWAGTGMASDMTESQWHYI
HQQGLQALDPDQALDAWEPVLAQPEQSTSVAILSLDLQSDKVTALPLIKPLLPEEVSSEA
KALSCSDKGGEKGDQDNQQAIEPTREHLQQLIISGLQRILPGGASHLDMGRPLEGQGLDS
LLGVEFRRYLNNKLALNLPASLLFDYPTIKTLIDHLMETLDSQSDNRGASDSPSPDAIKG
KKDAIAIIGMGCRFPGGVTSPEQFWQLLEQGTDAITSIPDRGWEPEAFYSHEAGTPSRMI
CRAGGFLDHIYDFDNEFFEVLPKEATYLDPRLRLFMEVAWEALQRAGQTCTGLLNSMTSV
YAGFCGSEYQSTVMADADTITPYSLLGTSFSAMAARLSYWLGLNAANLAIDTACSSSLVA
VDLACQSLLQGHADLAIAGGANLILGPESSIYFSQLKALSPTDRCHSFGDKADGYVRAEG
CGVVVLKRLSQALADGDRVDGVIRATAVNHDGQSQGPTAPNGRAQSRLLQSALQSAGVNA
EQVAYIEAHGTGTPLGDPVETNALADVFASPDKSLLIGSVKSNIGHTEAAAGIAGLIKTV
LCLQKRYVPPSLNAQQVNPRCTALLPHSDNGEEKPPSLKVVTAGTSLPDADQPVLAGVSA
FGFSGTNAHVLVESPPHNKQSEQPSFAETVLIILSAKTPRALMMQAVNLQQYIDEYPATN
LEQLAHSLALTRDGFAWRLAFLADSLADINQKLEQYLSLVRSDSAPDKTTAVTEDKWDGL
WQSSPESDMPERHRDNVPVAPSLALTTLADLFTQGYDLDWSVVYPNVRRPLLRLPVYPYN
KTTFRFQSHPQKQPSYKQQAEPRHPQGFQLKGRCWTQYPLSATDRPDEFPIDQENQLLEI
LNQLSVRAIMEALPVLGVETTPGCTFDPEVFPDPLSAHIPRRRLYRRLLTILRNNGYCLP
VADGHSWQWQEPHQAASVNTLIPEQQKSHPAVRLFKRCAPQLGQVLSGTVDPLSLVFPDG
DSQDVMGIYRDMATSRLINQQVAQQVAALARGLSGPVRILEIGAGTGSTTESVLRELADT
PVHYTFTDIGQRFVTMARSSLIGLDNPNHRFTFETLDISQNPAGSPVSQLGPYDIVIAVN
VLHATPDIQQCLKHIRTLCAPSGQFIFVEMLKPVPWLDLIFGLLDGWWCFTDHPQRTEHP
LINASQWFEQLSAAEFHGGRVVPVPGSGAFQKLLMASASDVVLLGDPEQGADKDTRHWLC
ICSSATDVNGITGQLTASGESCEWLQLESVANAQSLMERAPTDILYFPAVDGEGLLEQVW
SACEPLLIFLRRLLKVEHDLDSTAVEVRSFWMITRGAQPFDDETVPDSLSASLALSCTAG
LLRAIHQEMPEIHCRHLDFSAESSLPQQRPQLIETILSESILSEPMLILHWHKGECYRLT
MDSLPAESPRAVTLTKNGSYLITGGFGAVGQAWMEYLVEHGARTLILLGRNSPSQSVEKR
LASLRADGITIHCVHGDIGQPQTLAELFKKDWLQAGDGLKGVIHAAGTIHDITLAGLSWE
VMADVLSAKALGAWQLHQLTCGRALDFFVLCSSVVTVAGGPGQGAYIAANLLLDTLAEFR
IRSGLPACSLNLPVIPDFGMAARHPPRPEALAAFARDGVYPMQASSLSVLLAQTMAQSHC
GQLMVYPEPAASSVTADGIKTDTRQTGIDDSRSKDKLTRSELDRLLCQSLGWPEDHQLSP
RQSFREMGLDSLVAVEIRSRLMKRVGRPLPISLLYDFPTPERLYSFLTENADDPAPNSKP
CTSTAPDRRIAIIGMGCRYPGGADSPEEFWELLKSGTDAVGPVPKSRLNTMTGTGFSNIE
GGFLENIYLFDAGFFGIAPAEARELDPQLFVMMQTAWNALERAGQRRETLYGSDTGVWIG
LYANGHQGRMLNLPDSAINATNLINSEHSAMVGRLSYSLGLQGPNMPINTGCSSSLVAIH
QACLGLLNDDCSLAVAGGVSLIERPGHYPMLARMNVLSPRFRCRPFAADADGFVPAEGCG
MVVLKRLEDARRDGDPVLAVISASAINQDGHSQGPTAPNGEAQIQLLRKTLKRTGLEGSD
IDYMEAHGTGTRLGDPLEARAVGEVYGRGRRDSELLWMGSAKGNIGHSEAAAGVAGVIKT
VLAMNHGSIPASLHCSELSPEIPWHSLNLTVPREQIPWPVNTKDKRRAAVSAFGISGTNA
HLILEEPDHE
>E5B8A7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Erwinia amylovora ATCC BAA-2158|TrEMBL
MTGKVAVIGHSFEFPSVTNINDFWDGLINKRCFYHNAFTEGDEHIDAWGSVVNLKGFDHH
FFGYSYNEACKMDPQHRHLLQHCWWAMENAGYMNKKRLPVTAVFASASENHYLLRNLAGE
LRAGTENEVLLGNLPDFLATRIAWKIGATGQAFTLQCGCSSGLAALHQARVTLLTGQAEM
ALVGAVSLAASHQEGYDYLAGGIRSADGKVRVFDCDASGTVFTNGVAALVLKPLQKALEH
GDNILGVLESSALNNDGDDKAGFTAPSVSGQCRVIRRAMKVANIATEEIALYEAHGTGTR
LGDPIEFAALSEAWPDISSSEPTCALQSVKANLGHLDTVSGLAGVIKACMVLKHRQLPPQ
LNFQNPNPHIRLKNSPFFINAEPRMLAEKARFACISALGIGGTNAHVILSGAPETPTSSA
RPSPSVFLLSAPNQKALGRLQQSWAKWSGDDGAIEKAAAITRLGRTDFRVRQSLVASSVD
ELKAGISKAVKGTIAAGNAPFVVLMFTGQGAQYAGMGKHLYQISSFFRDRLDEKLAILQQ
LSGHDYRAILFEHQEDIHIPQHTQPGLLALEVALAEYLCNCGINADLMLGHSLGEYSAMV
VAQVLSFSDAASLVLLRAQLVQKTEPGTMCSVMAGVETLHPLLDDMAVDIAALNSATLSV
VSGRENEIGRFMANAQQNGIFCQLVKVKRAFHSRLLEPILPAYREALQRVSFSAPRVPVI
STLTGCEGSYEQFNQPDYWIRQMREPVAFAAAVKCAASRAENLCFIEVGPGQTLKTLASQ
NTHHPCINLMPHPAEVENAEKVLATAFGQLWECGVDIQWQNMNDRPIMPASPTPPNYPFE
LTECWTVPPTRSEHLALQSYQACWVPVMPLMPAAEGSSDWLFITDGSLFTAELAQTLGNM
LMQQGAKTRVAELEADSSSQMLKNAPANIALLFHPDTFRQETFKPLLILLELIRHWQGQG
PRRLSIITRAAVDLLTSPCPALAALVSAVKSLNQEYPALATRLIDCDGQDDALLARELTA
TSPVVVALRHSDRFSEGFLLSPVQENTCDAEIPRSIVILGGGGQVGLQYAKAFLENSQAH
VRLLQRSSLASLQSRTDKASVQRASRITDLMRRWPGRLTLGEADVQSHSSLLAACLQAKE
EMGSLDTLIHTAGVDASMHYQLIKDVDAQFCHISFAAKSQGLHNMAEVATTLAVPHCHVI
SSISSALGGIGMYIYGSLHAWLDAAVAELRRQHPSRWTSLNWEAWEFGNDEEVPDDFRQG
AFGSELNRYAMQPAEGRRLLWQCWRGLNGQRIISNVDFQHRYREWVENQHDSFASAENES
PHKAPRPEMNSEYQSAQNQTEEKIVAVWESLLGLKGIGIDDNFFELGGHSLLALRMTGQV
NQLVNSAMSMVDIFQYPTIRKLAASVTETRDYDAARNDAVLRAQKRRRLQSSKRA
>A0A5B7V411|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MVTEDKIRYFLKRVTADLHETRERLRDVEAAAGEPIAVVAMGCRYPGGVRSPEDLWDLVA
AGRDAVAPFPDDRGWDVEGLYDPDPDRFGTSVAREGGFLDDVASFDAGLFGVTPREALTL
DPQQRLLLEVAWETFERAGITPAALRGSRTGVFVGTSSQEYAMLLQGAEENFEGYSTGFL
ASVLSGRLAYTFGLEGPAITVDTACSASLVALHLAVQSLRQRECATALVGGAAVMPTPSM
FVEFSRQRGLAPDGRCKAFAAAADGTGWGEGVGLVLLERLSDARRNGHPVLAVVRGSAVN
QDGASNGLTAPNGPSQQRVIRAALANARLSLSDVDAVEAHGTGTALGDPIEAQALLATYG
QERDQERPLWLGSLKSNIGHTQAAAGVGGVIKTVMALRRGVLPPTLHVDEPTPHVDWSPG
TVRVLTEGRAWPETGRPRRAGVSSFGISGTNAHVILEQADHDGFPAPATDPAAPAAADAT
AGAAGPLPWLVSARGDRGLREQAALLRDHVRERPELSPADVGLALLASRTAFDHRAIVLA
DDRDGYLAGLDAVAEGRSAPDVVAGVAREPGKPVFVFPGQGAQWEGMAADLYRDSPVFRD
RLHACAAAVAPHVDFSLVDVVCGAKGAAPLDRVDVVQPALWAMMISLAELWRSHGVEPGA
VVGHSQGEIAAACVAGALTLQDGARIVALRSRLVAERLAGSGGMAFLALPQDRARERLAA
WGTRLAVAAANSPSSVVVSGDAEALGELLAAAEQEGVRAIRVAVDYASHSAQVETLEAEL
LAVLAGITSRPAAIPFFSTVTGGLLDTEGLDAAYWYRNLRRTVRFEPTVRGLLAAGHRTY
VEVSPHPVLAVSVHEILESAAAEGTVLTSLRRGEGDARRVSTSLAEAHVQGVRVDWSGRI
GPRARLVDLPTHAFQRRRYWPDGAQAAVRAREGDDSAAAGFRRRLAELPDGAGERLVLET
VCEHAAAVLHQDPADLDPTRAFTDLGFVSMTAMELRNRLATATGVRVSPAAVFDHPTAER
LAAHLRTLLTGGQEGAAAPLPTGPVADEPVAIVAMGCRFPGDVASPDQLWELVAAGRDAT
SSFPAHRGWDVADLYDPTPGTPGRTYVRRGGFLHDADRFDPLLFGISPREALAMDPQQRL
LLEVAWETFERAKLAPDAVRGSRTGVFVGLSGQDYLPLLTADPDESAGHLMTGTSTSVAS
GRLAYTFGLEGPAVTVDTACSSSLVALHLAVQALRQGDCTAALVAGVTVLSTPGAFVEFS
AQGALAPDGRCKAFAAAADGTGWGEGVGVLLVEPLSKARREGHEVLAVIRGSAINQDGAS
NGLSAPNGLAQQRVIRQALAQAGLEPRDVDAVEAHGTGTTLGDPIEAEALLATYGQGRPA
RSPLWLGSLKSNIGHTAGAAGVGGVIKTVLALRRGVLPPTLHVDDPTRHVDWSSGAVELL
TEARPWPDTGRARRAGVSSFGISGTNAHVILEQAPTEPRTPTADLAPTQGLAPAEGLAPA
EVPRPVAALPVLPWTLSGKTEQAVRQQAERLRQFTAGRPGLAPADVARSLASTRAVLEHR
AVVLGEDRASLLAGLARIAEGGQDAEGGPDARRVLRGAARARGRLALHFSGGDTHASGVA
PSAGAAPSGEAAAPAGPAAGPATPAAPADPAYAHLPVHAAALAEVAAACAAHPDAPAPGA
SRALARFAEDVALFRLLAHWGVTPDHLLGHAVGEVTAAHCAGALSLADAVALALALDQEA
DGVHRVAKELTFRPPVIPLVSGRTGRPVPYEELSTPEHWSRLSRETGTPDEAVRWLDSQG
VRDHVEADRDGATVSALLAALARLHVGGAAVDWDTMLTDVGATLVELPTYAFQHERYWPE
PTGSPLGASGPGRGSERAERGREFRARLTAAATGDERRELLADLVRTQVAAVLKLADAAG
VADDRNLPELGFDSLTAVDLRNRLGAATGLRLPPALVFQHPTVPDVARFLAERAETAGPE
GAADAAPAAGARFTLGPLLARAGELGRTDEFHELVRGVARFRPTFDAPDERLRPARVRLA
RGSAAAGPDLVCFPTFAVGAGAPQYARLAAAAEGEHDVWAQPVPGFDWREPLPATVDALA
HLLADGLGARADGGPAVLLGYSAGGWIAHATAAVLEERGAGPAAVVLLDSYWPGSAMIPR
LHARIDRARATGAPDVLWTEDTGDDAYLTALAHYAQLFETWRPREIAAPTLLVRALEPAT
EPDFDEPDFDEPAADGPAPVGSPAAAADDWRPRWHLPHTAVDTPGTHFSIIREHSEPALR
AVRDWLGGLH
>A0A5B7V325|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MANEETLRDYLKWVSADLHQTQQRLKDVEAAAQEPIAITAMSCRFPGGVGGPEDLWRLLA
EGRDAISGLPTDRNWDLESLYDPDAAGKQGTSSTAHGGFLDRVAEFDAAFFGISPREALA
MDPQQRLLLETAWEAFERAGIDPATVRGSRTGVFVGTNGQDYAPLLFEAEEDVEGYVSTG
NAAAVESGRIAYTLGLEGPALTVDTACSSSLVALHLAVQALRQGECGMALVAGVTVISTP
GVFTEFSRQQGLAADGRCKAFAAAADGTGWGEGVGMLLVERLSDARRAGRPVLAVVRGSA
INQDGASNGLTAPNGPSQQRVIMQALANARLTAADVDAVEAHGTGTTLGDPIEAQALLAT
YGQERPEGGQPLWLGSIKSNIGHTQAAAGVAGLMKMVLAMRHGVLPQTLHVDEPSPEVNW
TAGAVELLTEAREWAERGDGGPRRAGISSFGVSGTNAHVIVEQAPPVEEPTAEEASATPV
PEEASGTPVVPGVVPLALSAKTPEALHAQAGRLRAHLQSHPESGTDDLAWTLAVARSRFE
HRGVVLGRDRDDLLAGLERLAEGDATAGGVVTGRAVSGAGRAVFVFPGQGSQWAGMAVEL
LESSPVFAERMRECADALAEFVDWDLLEELSGDRFDRVDVVQPVLFAVMVSLAAVWQAAG
VKPAAVVGHSQGEIAAACVAGALSLRDAARVVALRSLAIRELSGKGGMVSVPLPESEVRE
LIAGWAGRIEVAAVNGPAQVVVSGEPEALEELVAHCVGQDIRARTIPVDYASHSSYVEQI
EAQILEALEGVSPQEAQVPLFSTLTGAWLDVPMDGGYWYRNLRQTVLFEHATRGLLAEGH
GLFLEMSPHPVLTVPVQATIDATDSQAATLGSLRRDDGGADRLAASLAEAHTYGAELDWK
ALFPGTRATVELPTYAFQRERYWPKAAPAGAGDVVFAGLRAAGHPLLGAAVSLAGAEGHL
FTGRLSTQTHPWLVDHAVDGAILLPGTAYVELALRAGDEVGCGHLEELTLEAPLVVPEQG
AVQLQISVGGPDGSGRRELSLFARPQDDTDDTPWTRHFTGSLLPAAPAEPSAEAGELSAW
PPARAERLDVSDLYERLTANGHGYGPLFQGLRAAWRRGDDVYAEIELPQEAHVDTEAFGL
HPALFDAALHAIGLGDFIERTDRAHLPFVWSDVTLHATGATTLRVRVTSAGTDTVAVLAA
DATGQPVVSVGSLALRALSEEQLTGGPRLDALFQVEWTPVDAPATTDEQLASVALLGDDA
SGAPLSARRTYADLDALTAALDEGADLPATVLLPLFPVTPAADGTRGTVELDAVRPLVER
ALDAVQGWLGDERFEASRLAVVTRGAVAAGADAPDPVAAAVWGLLRSAQSEHPDRFALLD
LDPAGTDDALVAAALAADEPELALREGALRAPRLTRVPLPETTGDSGTGDGSWGDGTVLI
TGGTGTLGGLVARHLVTRHGVRDLLLVSRRGEAAPGAAELRAELTESGARVRLAACDTAD
RAALAALLDETGAGLSAVVHVAGALDDGVVTALTPERLDTVLRPKADAALHLHELTAGLN
LSAFVLFSSAAGVFGTPGQANYAAANAFLDALAHHRRAQGLPATSLAWGLWAQASEMTAH
LGAGELDRRTRAGAAPLTSAEGLALFDAAHAAGHPLTVPVRLDLAGLRARAASDGVPPLL
RTLVRAPQRRTAAAAGQQEGSALAQHVAALPEADREEEVLTLVRGHAAAVLGYPSADAIA
PDRAFREVGFDSLTAVELRNRLTAATGLRLPATLAFDYPAATVLARHVLEELLGTDAATL
PRGTARTTAGAAPDDDDPIVIVSMSCRYPGGVTTPEDLWRLAADGVDAIGDLPGDRGWDV
DALYDPDPDSAGSFYTREGGFLYDAADFDPAFFGISPREGLSIDPQQRLLLETTWEAFER
AGIDPATARGSATGVFVGVMYNDYATHLLSAPGGLDDLEGYVGNGSAASVASGRISYTFG
LEGPAVTVDTACSSSLVALHLAAQALRQGECDMALAGGVAVMSTPGTFIEFSRQRGLAAD
GRCKSFAAAADGTGWGEGVGLLLLERLSDARRKGHRVLAVVRGSAVNQDGASNGLTAPNG
PSQQRVIRAALASAGLSTEDVDAVEAHGTGTTLGDPIEAQALIATYGKERAAERPLWLGS
LKSNIGHTQAAAGVAGVIKMVMAMRNGVLPQTLHVDEPTPQVDWSEGAVELLTEAREWAE
RDGGGPRRAGVSSFGVSGTNAHVIVEQAPPVEEPAAEEASGTPVVPGMVPLALSAKTPEA
LRAQAAQLRAHLLADTGPVLGDLAWTLATARSRFEHRGVVLGRDRDDLLAGLERLAEGEG
AAQGVVTGRVLGGTVRPVFVFPGQGSQWAGMARELLDESPVFAERMRECADALSEFVDWD
LLEELSGDRFDRVDVVQPVLFAVMVSLAAVWQAAGVKPAAVVGHSQGEIAAACVAGALSL
RDAARVVALRSLAIRELSGKGGMVSVPLPESEVRELIAGWAGRIEVAAVNGPAQVVVSGE
PEALEELVAQCVARDVRARTIPVDYASHSAYVEEIEAQILEALEGVSPQEAQVPLFSTLT
GAWLDVPMDGGYWYRNLRQTVLFEHATRGLLAEGHGLFLEMSPHPVLTVPVQATIDATDS
QAATLGSLRRDEGGEARLMASLAEAHVHGAELDWKALFPGARIVADLPTYAFQRQHYWPE
FADADDAGPLAVDEVESRFWEAVEREDLQQLAAELEVADGSAAELGAVLPLLSSWRRQRR
ERSEIDAWRYAVTWKPLATSSLSSSALSGQWLLVLPESAGDHPWTAGVSDALARSGARAV
ELRLTAAELTREALAVRLREFAGAEFAGVVSLLGFEESVHAEHAGVPAGLAGTVALVQAL
GDAGIAARLWAVTRGAVSTGRSDRVESPVQAQLWGLGRVAALEHPDRWGGLIDLPEAYDT
RAGARFTAALAGIEDEDQLAVRGSGVAVRRLVRSETAGQAGPWAPRGTALITGGTGAIGG
HVARWLAREGVEHLVLTSRRGLDAPGAVELQAELEELGAEVTVAACDVADREAVVRLLDQ
LAADGHTLRSVFHTAGVGQTQPLDGMSAADIAEVFGAKTAGAAHLDELLDSEGLDAFVLF
SSNSGVWGGGGQGAYAAANAYLDALAESRRARGLPATSVAWGLWAGGGMAGDEGTEHLRR
RGLAAMAPERAIAALAGAVAHDETFVAVADVDWERFAPSFTSVRPSALIGDLPEVRRALA
DPDDTRSGAAKQGAPGSEWAERLAGLAAAEQERQLLDLVRGQAAAVLGYAGAEAVEPTRA
FRELGFDSLTAVEVRNRIATATGLKLPTTLVFDYPTSAVLAGYLRTQLVGESETAAPVAA
GRVADVDDDPIAIVSMSCRYPGGVTSPEALWHLLAEGADAMSDFPGGRGWDLEALYDADP
ANRGTSYARQGGFLYDADQFDPVFFGISPREALAMDPQQRLLLETSWELFERAGIDPAAL
HGSQAGVFVGASSQGYGSGLRETPEGVEGYLLAGGATSVVSGRLSYAFGLEGPAVTVDTA
CSSSLVAMHLAAQALRQGECDLALAGGVTVMSNPGAFIEFSRQRGLAADGRCKAFAEAAD
GTGWGEGVGLLLLERLSDARRKGHQVLAVLRGSAVNQDGASNGLTAPNGPSQQRVIRAAL
ANAGLTTADVDAVEAHGTGTTLGDPIEAQALLATYGQERPAERPLWLGSVKSNIGHTQSA
AGVAGVIKMVLAMRAGVLPQTLHVDRPSTHVDWSEGAVELLTEAREWAGREDAPRRAGVS
SFGVSGTNAHVIVEQAPVEEPAEVVEPVAPVTAVPWLVSARSADVLRAQAERLRAHVADR
EELDPVDVGWSLLSGRAVHEHRAVLFGRERDEFLTGLDSLVSGGPGVVSGSVTEGRLGVV
FTGQGSQRIGMGRELYETFPVFADALDEVCAHIDPWIERSLQSVMFGADAELLEQTGYAQ
PALFAVEVALFRLAESFGVRPEIVGGHSIGELAAAYVAGLWSLEDAAQLVAARGRLMQGL
PEGGAMLAVQATEADVLPLLSDRVGVAAVNGPAQLVLSGERTVLEALEQTLRGEGRKVKW
LKVSHAFHSPLMAPALDDFRKVAAKLTYQDPALPVVSNLTGELAEPAELKDPEYWVRHIR
EAVRFHDGVKALAGQGVTTLLELGPDAVLTAMAHDTLTEPAAQAGLVAAVRKDRPETDTF
LAALAQLHVRGIGVDWNPLYAPAESRRRVELPTYAFQHQSYWLRQSAGAADVESAGLVSA
GHPLLGAGMPLADSDGYLFTGRLSLAAQPWLADHAVAGRVLLPGTAFVELATYAGGQIGH
GVLDELTLGAPLVLPERGSIQVQLRVEAPDSTGRRALSLHSRPEPGDGAEGLSADAWTKN
ATGTLTESATDAPAASDDLTSWPPRDAEPLTVDGLYEGLSTAGYDYGPVFQGLRAAWKRG
DEVFAEVVLEEDEHTQAGSFGLHPAILDAALHARAAGAAAPTEPGTEPATGGLPFTWTGV
TVHATGAAAVRVRLAPNGTDGVSLDVADATGTPVASVDALVFRPMSKDLIERMSGQNPHA
DSVFHVEWKPQALTAAEPVALISYEEPDAGGEESAAVVWQAGAPGASDGELRPETVSARL
AEALGVVQGWLADERSASSPLVVVTRGAVAADATVPDPVGAAVWGLVRSARSEHPGRFVL
VDTDIDTDTDGGVDAAVLGSVLASGEPEVAVRGGSLWVPRLSRVAPPATDGVPWGQGSVL
VTGAFGGLGRVVARHLAERHGVRELLLVSRRGLEATGAAALRDELQALGTQVTVAACDTA
DRDALAALLDEHGADLSAVVHVAGVLDDGVVTSLTPERVRSVLRPKTDAALNLHELTAGL
DLSAFVLFSSASGVFGGPGQANYAAANSFLDALAATRRAQGLPATALAWGLWAQDSAMTG
NLADADLQRMARGGVLALDTDEALALLDLAPASEHPALVPIRIDTAALRTQPQETLAALF
RGLVRPAVRRARGADTDAAAAPADRTDSLAARLAGRSGAERDRILLDLVRTHVAGVLGYA
SPNAVELSRGFLELGFDSLTAVELRNRLNAETELRLPSTLIFDYPNPAALAEHLSEELPT
TAGTTDAAPVAPGDLDTELDRLESVLKAVGGDTDGTERDRVAGRLRSLLTAWDTTRDTAA
PVTEQRQELDDIEGATADELFDLLDNELHTPAETSPNTSSDTGSDTDRPDRFEEAL
>B8MCM5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MAVQELTEDASMPIAIVGIGFRGPGDATNVESLWKMISEGRESWSKIPKDRWNHDAFYHP
DANRHGTYNVTGGHFLQQDVSQWDAPFFQMSAAEAAALDPQQRLLLECTYEAMENSGTTM
EQFCGSDTSVFAGAFTTDYTDILWRDPESTPMYQCTNSGQCRSNIANRLSYFFDLHGQSV
DVDTACSTSLVGLHLGCQSLRTGEAKLSVVAGVNVILSHEAWVTMSMMRFLSPDGRCYSF
DERANGYARGEGVGVLLLKPLSDALRDGDTVRAVIRGTGASQDGRTPGITMPNGVAQERL
IRGVYERSGLNPLGTSYVECHGTGTQAGDPLETRAVSRVFCEGREANNPVRIGSVKTNVG
HLEATSGVAGVIKAVLMLENKVYLPNRNFQKANPRIPLEEWKLKVPLAVEPWDGPLPRRA
SVNSFGYGGAIAHVILESAKDYLTLRGYHGHFRTTKSLVTLQLKSEYTNGHSNGTTNGHG
NGIINGYSNGITNGHPNSAVNDHSNGNGWKENSHNLPEEDSARLFVLSSFDESTSKRQVE
NFRQYLQERVDDVGPDFLQNLAYTLNERRTHHMWKTAVVGRSTTDLVYSLENGATFSSSG
NKKRKLGFVFTGQGAQWCGMGKELISTYPLFRASLERAAACLKDVGAPFDVITELTRDPE
GSSINRALYSQPLCSAVQIALVDLLTSFGIKPSSVTGHSSGEIAAAYTIGALSLEDAMHV
AYFRGVASTSLAQKGIFKGSMMALGLSKEDAIPYLARLTKGKVVVACSNSPSSVTISGDE
TAIDELLVIMEEDKIFARKLIVEVAYHSHHMAEVEKEYRDALSNIKVQTNSEGEFFSSVT
AQKAVASELGPDYWVSNMLNEVKFSESLQQLCLDTSSGKKTQKRNQQSQIDDIIEIGPHS
ALAGPIKQIIRANEKLSSSSIAYHSVLTRNKSAVDTVLKLVSSLFTLGYPVDLSTVNRMS
STEKLSVLVDLPPYSWNHSNTYWHESWKSKAYKNRPFPRTDLLGALERTCSPMEPRWANH
IRLSEVPWVRDHVIQANIVYPAAGYLVMAIEAATQRAIQRSVPTIAGYNIREVVIGAALV
IPENPGEVEVSVTLKSYSDSMISPSDLWDEFIVSSVSGDDRWTEHCRGLIAIQTPPKSAN
VIDGESQKAGDRKNLVSMIDRFNEECQKEINVAQFYQTIAKLGLEYGETFACMSEARASP
GCCVGSIKIPDTAAVMPQKYQFPFVVHPATLDSLFHTIFVSLDADEMKDPAVPVSVEHIY
ISNSITSTPGEELVAYTSTEKKDPRTVSASLTVLSAHQGAESDPVITIRGINCTTLGVAE
SQDASSESQSRAYNFDWKPDIEMLSGESLATVIRSGPSVQSLNIRHRFEVAAFYLLKSVI
EGMKGSLSSITTSYQQDLWDLVDRVVKKTVEENQSSLAEIWISAGKDEQNVFLDKIKAYG
HEGRTLLHIGKRLPSLLRGELEPSSLLSEIELSGFFSSSDTFINSSTVAKYLELLAFKQP
NVSILACGKLSGFLSIPVLAALDSKAGQLPYFSKFEYADDDFDLSDLVKAKCSRWNGLIS
RKELDIAVDPSKQDIALGSYDALIVFQSLGSENLVRSTLENAHKLLKPGGKLLLVGRPMK
SLIVSTMFGFLPSLLPAKGKSDNGDAIVSREVWTDILSETRYSEDVIIPNGTDTTKHAAA
FLTALPTKPSAPKYPNTLVIWDGAEKSISTRTLQEQLNAHHIDVDISSFQTAKPRKDQVC
IVLSDPSSQTLINTSDIQWDVLKTIFLESGGVIWVTRGATILSSDPSSNLISGIARTVRS
ENGESPILTLDLDSATLLDDAKTAQLIVTLFERHFQFGSAPKGIEPEYAERNGTLMIPRL
IEDSQLVKFITNTTAEPKPELQPFRQPGRPLRMHVGTPGLLDSIYFVDDNRFDDGLPADW
VQMEVKATGFNFKDVMTALGQIQLKSLGWEASGVVTAIGKDITHVQVGDRVLSYGAGLFS
TDYRGPADRFHKIPEHLSFERAASLPVTYATAYYSCHYIARLQKGETVLVHAASGGLGQA
IIELCQLVGAEVYATVGTADKKQFLMHYFKIPEDHIFFSRNGSFAKGVKRMTKGRGVDVI
MNSLAGENLRLTWDCIAPWGRFVELGQRDIMINTRLEMKPLSRNTTFAGFLLDDLFEQRP
EVASKVIAEVIDLFRTEAIRGPAQVHSYPISEVEQALRTMQTGGHMGKLVAINSPQDMVK
VVPQDNTKSLLHANASYMLVGGLGGIGRATALWMADHGATNLILVSRSGPNNVDAKDTVR
ALESKGVKAAVYSCDITDFAQVKSTIALAKQDMPPIKGVIQGAMLLRDTLFQNMTLEDYK
AVLYPKVQGTWNLHNHLPKDMDFFIMESSVSGIIGNATQAAYAAGNTFLDSFASYRNSQG
LPATTIDLGAISDVGYLATNSDLREAMQRQGFELTDKKTLMSLIHFAIENPRRPALLSQC
VTGLGVWNEGNSLDSLNLPLFAHFRSLTSQGSGDVEAAGSAGQLRKNLRKATSLEDASEL
ICTALISKIASRAGVGVEHVNVGNPISDYGIDSLVAVEIRNWISKEMNSTIPILELLANT
PLSQLATKIAQRSRLVQLNEAEKV
>A0A3N6IU76|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI97-07|TrEMBL
MLETPASGGGKQTPLTRALDTIRTLRQQLGEQRGNQPVAVIGAGLRLPGGIEDLDGYWTA
LAEGRDGVRPMPAHRKGPFAEDWEGLPQRGGFLDEVLDFDAEFFGISPREARHLDPQHRL
LLEVAWEAMEHAGLPSRTLAAARAGLYLGVMWQDYREWCEGEPDAYWATGNGHNFAAGRV
AYALGLTGPAMTVDTACSSSLVAVHLAVQALRRGDCEIAFAAGANLIMSPQTMKLVQETR
SLSPDGLCKTFDARANGFTRGEGVGAVLLKRLDHALRDGDRVLGVIRGTAVNQDGRSSGF
TAPNVLAQVSLIETALADAGLEPSAVGYAETHGTGTALGDPIEMDALATALGRRNGGAPL
PVGAVKANFGHLEGTAGVAGLIKAMLCVARRKVPPVVHFRTLNPRIDLSGTGMTVPGTLQ
DWSPESGDCASVSSFGMSGTNAHAIIGPLHADELPARQDAGHPPAVTGFEISAKTSEALR
ARAAQYADRVASLAPADYPAFAYTATAGRSRLDVRARISAADPETAAAALRALAAGEPSP
LLTLTEGQDSGGEDPAAGLPRRLVDLPGYPWQRRRFAPEQAAADPASGVPALPTRHAVVW
EAAEPRTAVPGAELVLAGDDAALLAALVDRAARLGLRGTVLAPAPAVLPDGWRHAALPGD
RAGWARFWEGDTTPGPAPLVLAFRATAMPGAQDGVPGTADPAEPGARLCASVTVAVGALA
KSGRAHRAFAVTRSACRSGPGDRVAPTDHGLLHGLAPVLGLELGAAWGGVVDLADEPAAE
DLDTLLAFAVHEAAAPGDGHSPLEDLAAVRGGALRVARLRESAEPAGTLEVRDDATYLVT
GGLGGVGRELTAELVARGARHLLLIGRRPQDQLSAEATALLDELAGAGVRAVYRGGGCDT
AEAVGAACAALEGLPPVRGVLHAAGTLDRAPAEETGVEEFAASLRGKTAGAWLLHRASRD
WPLDFFVMVSSVSAVWGTERCAAYSAANGGLDALAAHRVSLGLPAISLAYGPWDLGGSGM
ADSASRDTFARVGVGALDAATGRAALDGRAPDGSGHLIVCPLDTSRFLTIMSRFRRRGLF
GVAAVAEGAPAGAVIRQEPSVTGELAALPDRARAGAARGHVARIVAAQLGHDSAQAVGDD
TGFFDLGLDSIMAVDLVGRLSQAFGVVLLTADVFNHPTVSRMAEHLLTADRAPEPTAPSA
TTGPAVAAVRERPASPQDPAAVVPAADAPPSRDADREPVAIVGMAGRFPQSDSVDELWDL
LREGRDPVGPVPDGRYERTAFHGGGGEPARVTTDQGGFLRDIARFDASFFGIPAREAESL
DPQQRLLLESAWHALENGGIDPHSLKNSRTGVFVGISYADYARLLAESGPEHLDAYYSTG
TSLNAAAGRLAYSLGLNGPALAVDTACSSSLVALHLGVRSLRSGESDAVLAGGVNVILDP
MASVSASRAHMLSPDGRCRTFSADANGFVRAEGCGVLVLKRLADAQRDGDQVLAVIRGTA
VNQDGASSGLTAPSGPAQQTLLTDALSDASVSGADVSYLEAHGTGTSLGDPIELGAAWKV
LGPGRKPGEPLHVGSVKSNIGHLESAAGMAAVIKTVLALRHDLIPANLHFGAPNPHVDWP
EMNVRVVDTQTPWRSGAKPRVAGVSGFGLTGTNAHIVLAEAPAGARAAMSGEPAGATHLL
PLSAPDQDGLSRLSEVWEQRLTGATDEDLAGLVATATTGRGHFPHRRALLGTTRDKLLAQ
LSTPPPPRPARRPRIAFLFSGQGSQRFGMGRELYETEPVFRDVFDACDRELAPVLGGSLV
ELTLYGQDESAIDETRVTQPALFALEIALAALWESWGVAPALVMGHSVGEVAAAVHAGVM
DLGSGLRLIARRAALMQSTERGSMLAVTATEEQVLAWTAGTELDVAAVNTPAATVVSGTP
AEIDRLAEKLAADGVRTRRLSVSHAFHSRLLDPVLGELGDFLASSEFAPPKVPLISNLTG
ELAGPATIDADYWVRHARNPVRFHDGARRIEDQDIDVCLEIGPDRTLVNLVRAAGLAPDG
GVVPSLYRGAGDRAALLAAVKALYELGQDIDWQAVQAPRRIPRSSAPLYPFAATVHWRRA
AEPRAGRAAPDGRTAPAGPPWGTELRSPAVKGRVFVTERSTVYPPHLDDHRLFGTVQVAG
ASQTATVLSAIGSAGEPVVLEDLHFPRALVLHDGERYELQIIEGEADHGTRTVSVQSLLD
PERGRWQEHLTARMPAADPVAARNAPDPAAFIAGADRHLSGEAFYRYLRGIGYLLGPSFR
WVGDAWIRGNESLIRFDPPEGMNEDPADYQIHPGLLDSCLQSSVTFAVHEEDPEPQDQEQ
ALVIPFAAARVSFPGRPTPGQPLWGHVRAVMRDLPDGGFHQVDTADLHIFDGSGATVLAM
DGFRFRLASKAVLRSSLRHGTRHAYELAWTDSSPAPTGAVAVRPLHIAVAGADTQAGREV
LKAGEDLGHLMTALPEDTAGPAADLIIDARFHLTTGPTGPDTALDAALGLGRTLQAASRD
IPYAVLGGAGPEAAPVRETLWGLLASLEAEEGDRLLIRVTLAPGWDGTALVTALDRTLGR
NPAETRIEVGGGGVRAARLVPYRGHPVRDEAPAQEAGAALVTGGLGALGLSTAAILARHG
CTAVTLMARSAPDAAAQRVIGELAAAGTRVRVVRGDVTDPADCARAVSEAGLDAPLRTVL
HLAGATDDRAFGRVDRDALELVFAAKARGAANMAAALRGHTLNAFVLFSSASSVLGSAGQ
TNYAAANGFLSGLADALRADGIPATSVAWGPWIPEAKGGLAASESVRRAAEKLGIGSLTD
ETAERLLLAALTDGPERLVAVDLVPERFVAHLGDHPRAALLAGLTDHAGKDGGAAGPVGP
PGRPRGWLRAGGDGLDGLDADARTEALRQFIREATGETLGDPAGIDDDITFGDMGLDSIM
VIDLRTRLSHALGVDLLATVALDHPTIPRIAAHILGLLDENEPDTPPAPAPQRAPLTEAG
PDDLSELSFEDLVRAVRSEVSAPEGDRNA
>G0Q416|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MADANNRALRNKVAIIGMGCRLPGGASDHRTYWRNLVEGKDCITPTPPDRYDVSTLGSRF
RDKPGRLVGGRGGYIDGFDEFDPAFFGISPREADHMDPQQRKLLEVAWEALEDGGQRPGD
LAGGNVAVYVGAFTLDYKILQFADLGFTSLAAHTATGTMMTMVSNRISYCFDFRGPSLSI
DTACSSSLVAVHLACQALNNGESDLALAGGTLLHMAPQYTVAETKGGFLSPEGRSRTFDA
AADGYVRAEGVGLVALKRLDDAVRDGDRIHAVIAGSGVNQDGHTNGITVPNADAQVDLIR
RVCAEAGITPGDLQYMEAHGTSTPVGDPIEANALARALAVGRAPGARAYVGSVKTNIGHT
ESAAGIAGLIKTVLSIEHRTIPPHINLENLNPAIDPAALPYEIPTRPTPWPEHEGPARAG
VNSFGFGGTNAHVVLEEAPGPLPDTRPATSGASAGRRWSILPLSARNPDALKEMAAGIRS
ELAGANGPAVTLDDLGHTLAHRRQHLPERLSVAYTSRASLDEALAAHARGDAHPRVVHGR
ARDAADRRLVWVFTGMGPQWWGMGRQLLEEEPVFRDAVAACDRAMREFADWSLIEEMTAD
EPVSRMAETWLAQPANFAVQVGLAALWRSHGVRPDAVVGHSTGEIAAFHAAGVYSLRDAA
RVVVHRSRLQQTLAGTGAMLAVSLSEDEAERRVRPYSDRVSIAAVNSPTAITLAGDEAAL
TLLAEELRAEQQFAKFLTVEVPYHSVVMERIKEELLAELAPLEPRTALVPLYLTGAEGTA
RGEELDAAYWWKNVRDRVRFRSAVDRVAADGHRVFLEIGPHPVLGHSIGECLEAGGTSGL
TLPSIRRRENEGERFAASLGSLHNLGVAIDWNVLQPTGRPVTLPRHPFRRDRHWTEPRPV
AQVRLGHRDHPLLGRRTDRTEPTWQARLDTEDLPYLADHRIQDTVVFPAAGYLEMAAQAV
LRLTGGTTAVLADIDLRKALFLPDGEDRTVELSLSLENAAFTIASPTGDDGERAVHASGI
VRTGQRRRTAPPLDAPALRARSSRHLRGPDCYTALAALGYHYGPAFQAIEEVWIGAGEVL
ARIRPPRAIGEAAAGHHLHPVLLDACFQTLLTPLIPPTPEGAAPDTGIRLPLSLDEVALE
PIGDQPFWAHATLLPGDAGTTLGNLALYADDGAPLGRVLGFRAADVEKAATAVARTTIDS
WLAEPVWTDCPPLPAGDTGAAPVNADDRDVRGEPTGSTTGPRPAPATAARDHDWLVLADD
GGTADAFAALAAARGERCRLVRRGAAYTASADGAAFTVDPASDADLRRLLADLDRDGGPF
RGAVLHLWNLDAPALATCDRASLTDHTGAGAYSLIALARLLSARGTGGRLHIVTRGAQPA
LPGEGPEPLGAPAWGIGRVLRHQELTEHPGKLIDLDPRRQPGPDGDRAEAAALLGEVLSD
DEEEIALRDGGRRTSRLRPARELTRPLPPRLRADGSYLVTGAFGALGRLLCRTLVRRGAR
RIILVGRTPVPAREKWAGTDPATAEGRAVALLRELEALGAQPVLATLDITDEDALTGWLD
AHRRSGAPPVRGVFHLAGQVRDTLVADLDRAAFDAVHDPKTVGAHLLHRHLRDEPLEHFV
LFASIASLLTTAGQTNYAAGNAFLDALAHHRRARHLPALSLDWGPWATGMIEELGLVDHY
LHSRGMSSLSPEAGMAVLERVLGQDHAQLVVATVVDWPVFLAWYPSSPPLVAELAAAAAP
PADAASGNGFLDTFRAADEETRRTLVGDRFAALSATVLRTGTDRIDPATGLGELGLDSLL
AMELRARIHAELGVALPVVALLSGTPAGELAAQLHDGLTALASTDTPDGAPGAVELHHDE
GQYPLTQNQKALWFLKHLNPDGYAYNIGGAVEVNVTLEPDLMFEAVRRLIARHPALRTNF
LLVDGQAVQRVSENPATDLALFDVQGEDWESIHATIVQEYRKPYDLARDPLVRFRLFKRG
PDRWIIMKAVHHIVSDAISTFTFIEELLAVYEALRRNQEHRLPPVEARYLDFLNQQNAFL
AGPAAAGMLDYWRSHLPAEVPLLDLPVDKPRPAVQTHNGASEFFVLDDALSARVHALARA
HGVTPFMVLLSAYYLLLHRYSGQDHIVVGSPVTGRTRQDFSSVYGYFVNPLPLHADLSED
PTVAELLQQVRRTVLGGLDNQEYPFVLLVEELGLQHDPSRSAVFQAMFILLTHKVATEQY
GYRLEYIELPEEEGQFDITLSAYEDEAEGRFHCVFKYNTDLFLPETMRRMAAHYTRLLDR
MTRVPGEQPSSRLEMLGERERERLVEEWSRPTLPPAGPGEEPFTPVQTLIGRVAAEHPAA
VAVTLPTAHGEARRLTYAELDRRATGTAARLRALGIGEGSVVVLCLDKSPELIAALLGVL
RAGAAYLPLRPDQPADRLAHLVTATGAALVLVADDAAPEQTGALTVPTLGLAALERTEPH
PEGPAAAPGPDSPAYVITTSGSTGRPKAVRVSHRNLASAHAAWRQEYRLDTDVRTHLQMA
EPSFDVFTGDLVRALCSGGTLVLADRDLLFDTTRLYRTMRQERVDCAEFVPAVVRGLMDH
CTREGLRLDFLRLLVVGSDAWSVGEYRRLAELCGPGTRLVNSYGLTEATIDSAFFEGPVD
DLEAGAMVPIGRPLPNSTLHVLDAHGEPVPPGVPGELWIGGDGVALGYAGDLEQTEERFV
TRALGRGAGARPERLYRTGDIARWDAQGRVHLLGRTDGQVKLRGHRIEIGEIEAQLAQWP
PLARAVVTVRTDTGGDAALCAYCVPEPGAALDVRALRRHLARSLPSYMIPSHFTELPALP
LTANGKVDTAALPAPRAEAGDRPHEEPVTLYEISVARHWKTLLGREHVGLEDDFFELGGS
SIKLIELLHHLRTEFGVGVPVSRLYQVTTLHGMAATVEDVLLGTTADELPRLTFNAGQAP
ALFCFPPAGGHGLVYRGLAAQLPDYSVTGFNYLPGDDKVSRYADLIEADRPDGPYLLLGY
SLGGNLAFETAKELERRGRDVAHVVILDSRRILAAYEPDASGIAAFESELADHVRKHTGS
EAVAHETLAHAAEYLAFCGRTPNTGTVAATVSVITDEEKTALYAAGEHGTWHGSSTGATA
VLRGSGVHADMLDAKHLPRNAELVRSVLRGDAAHGG
>G0Q182|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MADQTAARTHGRHEPVAIVGIGCRLPAAVEDPNQLWQALLTGVDAVRQVPANRWNASAWA
EAEASGRAANRRGGFLDDVMRFDAEHFGIPPAEARQMDPQQRIALEVAYAAVEDARRSPA
GLGGTRTGVFMGAMWQEYPLFTQGAAEAIHAHSAIGWDNSVIPSRIAYALGLRGPAMGVA
TASSSSLVAVHLAVQSLRSGESDFALAGGVNLMLHPNTSVAMTKLGTQSPAGLSRAFDGD
GDGYARGEGCAVVVLRRLSDALADGDRVYALVHGSAVNNDGATDGLTAPGHEAQTEVLRA
AWENAGVAPHAVSYVEAHGTGTPLGDVTEAGALGTVFGPDRPAPLRIGSVKTNFGHLEPA
AGVLGLVKAALAVHHGVIPPSLHFRTPNPRIDFSAERLDVVTEATAWPAGPRFAGVSSFG
YGGTNAHVALGEAPGSAPVPTAPQADGPVCLTVSGTGPHALARNAARLANHLGRSTGASL
SDVAHSLATTRTQHPARGVVIAGTTDEAVAGLRALAAEESHGAVVTGTAADRGRVAFVFP
GQGAQWWGMGRSLWEQNDAFREAVTACDEALAPHTGFSVAAVVRGEDALAPSFTRTDVVQ
PALFAMYVGLAAMWRAWGVEPAAVVGHSQGEVAAAVVSGALSLADGARVVASRARAVQDH
APDGAMGLVERPVGEVVEELAAYGDALSVAVVNTARSTVVAGDADALDRFLAGVEATGAY
CQRVDVDYASHSPHMDVLLPALRERLTGLAPVEPGIAFYSSVTGERAAGSELDGDYWCRN
LREPVRFDRALERLRADGFGTFVEVSPHPVLQIALAQGTEADGSAVVVGSLRREHGGIEQ
ALRAPAELHAHGVPIPWQRVLPNPDPRRADLPTYAFDHRGYWLDEHDDVVPAVNGAAWRE
DVLALPEAERLGSLVTLVTEEAAALLGRPAEGVRPDLTLREQGLDSLMVVELRNRIGART
RVPLPTVLAFDYPTPQAIASLLLTHVDARYETPEAAPALVAAPEPPDDDDPVAIVSMACR
LPDGIDTPEAFWELLVDGGEASSPFPSRWDGWDLSTIEEAERAATGRRFERRGGFVRDVE
DFDAGFFGLSPKEALSLDPQQRLVLEVVWEAVERAHLRTASLAGSNTGVYLGAMSSDYDV
ARRWDVGSSDGYKITGNGSSLISGRVSYTLGLSGPALTVDTACSSSLVALRLACEALRSG
ACDLALAGGVTVMSTPQIFVEFSRLNGLAADGRCKSFADDADGTSWAEGCGVLVLKRLSD
ARRDGDRVLALVRGTAMNQDGRSQGLTAPNGLAQQRVLREALADGGLTPADIDAVEAHAT
GTVLGDPIETGALAAVFSGRVRPLHLGSAKSNIGHAQAASGVIGVIKMVMALQHEWLPRT
LHAEKPNTRIDWSGGELELLRQPRPWPRTRRVRRAGISSFGISGTNTHVIIEEAPQTAVE
DRPGDDVLVHPLVVSGTDEAALRAQARHWAEWLDAGPAASMRDIAHTSAVGRTHLDARAV
VFAADAAQAAAALRSVEPVPGTAPGKVAFVFGGHDARPPGTCRPLLEQSEVFRDAVAECD
AVLAPLTGWSVLKVLRGEEDRNGPEVLPCTLFATCLGLAALWRGWGVEPAAVVGDAHGEV
AAAVVSGALSLADGARVVALRARARSGDAVDGAIAGMVAARTSIPFHARPTGEAVPGPEL
GGAYWLRDLPEPESKTLDRALERLRGEGFGAFVEIGPPPQGGSGGVDQLWRAAATLFERG
FPLDWERVLGSRGARKVDIPTYAFQRRRFWLGELPSGPAAVTERRSTVSHPWFDAITTLA
GGGGHLFTGRLSLDDSPWLADHVVGGQVYVPGAGLIDAALSAARTAGADALTDLTLLEPV
VLLPGRTLRIQATVGDPDPHGRRPFALHTQPEDTDDPLVWQQHVTGECVTRAGADATVPP
DLHDWPVPDARALDVEAFYGRALANGLDYGPAFRGLRELSRRDGLYYARVSLPGALDPGG
HGLHPSLFDAALQVVVAGLMEEGAAPGPLVPFIWSDVELFRAGGRELAVRVSYEPGGHED
LAPATVWLADPAGRPVARIGGLKFQPGRRRGHPFAEHLYRVAFAPVHPRAEAPDSAGILV
VGDAELGAGLGADVVPDLDVLVKRLDDRADTPRQLLFARPDRPSAQEDDAERSAAETLRT
LQVCLGDARLQDTELIWITRDAVSSSPDDQVVNWAHAAVWGMVRTARTEQPERALRLIDL
DPGTPDLPLLARVIGTGGEPECVLRGGTAHVPRARPTVEQTDALVLPDEGGWHLHRREDG
RPAVTAATHGGGEPEPLAPSDVRVEVRAAAMSPEQAQALEFTGTVIEVGGDVTSVQAGDR
VMGRAATALGKEIRVAGTGLGPMPAHLTFARAAAGPSASAAPQDKGAFTAFDVRDAPYAL
RHAQRNAARKTVLTLPRALDPDGTVLITGGLGELGGALAAHLVRAHGARRLVLLSRRGGN
APEAGSFARKLEAAGAERVDLVAGDVADRAAVAAVLDGIDPGHPLTAVFHLAGVLDDGLV
EGFTAERLHRVMAPKVQGARLLDELTERLDLAAFVLFSSAAGTLGTAGQSGYAAANATLD
ALAANRRKRGQAGLSLAFGLWEQAGVGMTAHLGKGELGRLRRQGIGALTLAEGLNALDVA
LARPETQLLPVHLELGSLRHALGDAEAPPLLRDMLRRTTEGPRGEATGTAPSLDARMAGA
SEAERPALLLELVRSEAADVLGLPGPDSVPADRALRSLGIDSLTMVQLRKRLAKRLNTTL
PATLVFDYPTAQAIAGLLIHDTTAPRGNEK
>A0A2P4UBW6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinomadura rubteroloni|TrEMBL
MVNEDRLRDYLKRATADLRQARRRLHEAESRASEPIAIVAMSCRFPGDVQFPEQLWRLVH
DGGDAVGGLPVDRGWDVDKMYEDEGVTRVVEGGFLSDAADFDASFFGISPREALAMDPQQ
RVLLEIAWEAFERAGLTPDGLRGSRTGVFTGVIAQEYASRLTKAPAGLGGYFLTGTATSV
ASGRIAYTFGLEGPAVTVDTACSSSLVTLHLAAQALRNGECDLALAGGATIMSAPSIFAE
FSRQGGLAPDGRCKPFAAAADGTGWAEGAGLLLLERLSDAQRNGHPIFAVVRGSAVNQDG
ASNGLTAPNGPSQQRVIREALANARLAPGDVDAVEAHGTGTTLGDPIEAQALLATYGQNR
ERPVLLGAIKSNIGHTQAAAGVAGVIKMVEALRNGVVPKVLHVDEPTPQVDWGRGSVRLL
TENTPWPETGRPRRAAVSAFGISGTNAHVILEQAPEPEEQAEPAPRPEWHGPVPWPLSAR
GGAALRESAGRLEHVLAWHPEFDSVDIAYSLLTTRALHDRRAVLLAGDRDEALAALAAYA
RGESPAVIVEDVPQLEPGRPAFLFPGQGSQRHGMGRELYATYPVFAAALDEVCAHLDEHL
DRPLKDVMFADGDAALHETRYTQPALFALGVALYRLVEAWGVVPGHLIGHSIGELTAAHV
AGVLDLPDAARLVAARARLMQELPAGGAMLSVRAAEDVVRPLLEDGVSLAAVNGPDATVV
SGDAAVVDRVAAALDARGIRTRRLKVSHAFHSPLMDPMLDAFGAVAASVTFGPARIPVVS
NLTGAVATDEELSSPDYWTRHVREAVRFHDGVAALRAAGVATFLELGPDTTLSTLVQPGP
DEAAVPLLRPSRPEPHTFLTALARTHARGIPVAWTDQFAGTPGTVPLPTYPFQRQRFWID
APDTVSDATDLGLARSDHPLLRASVTLADGNTTVFTGRLSLRTHPWLADHTVDGITTVPA
SAITELALEAGRRAGRPRVQDLGLDIPLTFPADGAVQLLITFDVTDEDGLRPVFVHSRPE
AADADDEPWTRHATGTLAAVWPVVPVPTASWPPPDAAPVDVDALYDRLADEGRRPGPLFR
PLAAAWRAGDDLFAEAVLPEDADADGYVLHPALFEAALQLAGEGEDAAVLTPREWSGVTV
HTTGATAARLRLSPVPGTAGTFALTMTDAAGDLVATADAVRVEAAPAVRRAAPRSLYELR
WEPAGPPASVPDGLGGATLFEVEAASDDVPTAVRLATHRALDALRGALDADGPVVVVTRG
AVAAGPGERVRDLPGAAVWGLVRSAQNEHPGRFVLVDLDDAPASRDAVAAVLASGLTQAA
VRDGQLLLPRLARLTPEDAAPPALDGTVLVTGATGTLGALVARHLVAERGVRSLLLVSRR
GRDAEGALELEAELTAQGADVTVAACDIADRTALGTLLAGVDLAAVYHVAGALDDATLTS
LTPERIDTALRPKVDGAWNLHELTRDRDLAAFVLFSSVAGVIGNPGQGNYAAGNAFLDAL
GAVRAADGLPATSLAWGLWDPVSAMTGRLSDGDRGRIGRGGVAPLTAEEGLALLDLAVAQ
NRPALVPVRLDTSVLRAQAAEGKLSPLLHGLVPAPLRRAAASPADTSLAAELAGLDDAAR
DRALIELVRDHVVAVLGHSGADAVEVARPFNEIGFDSLTGVELRNRLSAATGLRLPSTLI
FDHPTPVALARHLRDELVGAADAVPAGHRAAPGTADEPIAIVAMSCRFPGGADTPEALWR
VLSEGVDTVGGLPENRNWDIDGLYDPDPDKSGKFYVNTGAFLYEAGEFDPEFFGISPREA
LAMEPQQRILLETAWEAFERAGLTAEALRGSRTGVFTGVIAQSYVPGLHASLSGGEGYFM
TGNTTSVASGRISYTFGLEGPAVTVDTACSSSLVALHLAAQALRNGECDRALAGGVTVLA
SPGIFIEFSRQRGLAPDGRCKAFADGADGTGWGEGAGLLVLERLSEARRAGHPVLAVLRG
TAINQDGASNGLTAPNGPSQQRVIRAALASAGLDAAEVDAVEAHGTGTKLGDPIEAQALL
ATYGREREEPLWLGSIKSNIGHTQAAAGVAGVIKMILAMRHGVLPKTLHVDAPTGEVDWT
AGSVALLTENTPWPQTGRPRRSAVSSFGISGTNAHVILESADAEEPAPADHDDSHDGPVA
LPLSARTERALRDQAGRLRDALAGTAPAAVAHALATTREAFDHRAVVIGAGRADLADRLA
ALAAGGEPGQVVTGTVGNPGKTVFVFPGQGSQWAGMAADLYATNAVFRDHLDACVRALSP
YVTWDPTDLSALESVDTVQPALWAIMVSLAHLWQHSGVRPDAVIGHSQGEIAAAYIAGAL
TLEDAAAVVALRSKTLTIITGDTTMASIPLAADAVDLPDGAYVAAYNGPNQTVISGDATA
LRELVENYQEQGVQARLVPVDYASHSPYVEPLKDDLLKALKDIRPAEAKIPFYSTLHNAF
IDTTTLTGEYWYENLRHPVQLHQAVEHLVRTGHRTFIESSPHPVLTYPLQQISEDLTALH
TLRRDKGDDVQYLTALASAHVHGVAIDWPTVLGTAGTGRVDLPTYAFQRRHFWLDAPTST
GDPAEIGLDAAEHPLLGAAVSLAAGEGSVFTGRLSARTQPWLADHAVGEAVLLPGTAFVD
LALHAGRQTGHEHVDELTLHAPLILPESGALQVQVTVGAPDGDAADVSVHARPDADAPWT
LHATGRLTAAPPEEPPALAWPPAGTQIPVDGLYERLAEFGYGYGPVFQGLRAAWRDGDDL
YAEVAVPEGTPDGFGIHPALLDACLHVLLLGGEGDGEGGGVRLPFSWGGVTLHAAGATSV
RARLSKAEGDAVALALTDASGAPVASVRSLAVRPVAPEQLAPPAGDRDALLALDWTAAAT
PAPLAPGAYTVVADLAELDAVPDVVVLTPAPSGGDVPAAVRATTIAVMEALQAFVTDERF
AAARLVVLTRGAVAAAPGEAPDVTTAPVWGLLRSAQNENPGRFTLLDTDDADASRAALAT
ALASDEPQLALRGGALLVPRLARRDAVPAEPAGLSAGTVLVTGATGTIGGLVAKRLVTGQ
GVRDLLLVSRSGRAAAGAAEIEAELTGLGATVEIAACDTADRAALAALLDGRTISAVVHA
AGALDDGVLTSLTPERLETVLRPKVDAAWNLHELVGADAAAFVLFSSASATLGNPGQSNY
AAANTFLDALAERRRADGLPGTSVVWGHWAEASGMTGHLGHADLARMSRGGIAPLTNEQG
LALFDAALADARPVVVAARLAPAALRARAAEGQLPPLLRGLVRVPVRTAAAASDGPGLAE
RLAGLELPERHRLLLDLVRGSVATVLGHSGAESVDAGRAFKELGFDSLTAVELRNRLNTA
SGLRLPATLVFDHPTPAAIADLLERRLVPEEVSAAERLLTELDRLEDELTRVESDADAEA
RARITARLQALARGWTGDAAGDAADRIEAASTDEIFDLIDNELGVS
>A0A1D2I430|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. AVP053U2|TrEMBL
MEPMLDAFREVAEQLTYTEPVIPVVSNVTGEVADPALLCSAEYWVRHVRDTVRFADGVGA
LAGAGVNAFLELGPDGVLTGMAARVLDGDEDVVSVPVLRKDRSEETALLTALARLHVTGV
DIDWDAWFRGTGARRTELPTYTFQREHYWPEPAAAPGAGAGQDPVDAAFWAAVEREDLQA
LSATLDLDGTVLSDVLPALSSWRRGLNERSLVDGWRYRVSWRPLTASASATTAPGSSMAE
GPWLVLIPAVLDGDPWAEAVAGALGADAVRVVCAPDDAALAARLAEAADGTEYAGVVSLF
AAAAAAADGGADRALPSGGAWPDALLDALDDAGIAGRPWAVTRGAVSVGRSDAGADPVQA
AVWGLGRVTALERPDRWGGLVDVDHVAGARTAARLRAVLTATGPDAEDQVALRASGAYGR
RLVRAAAQRPDAPWRPTGTVLVTGGPEGFAGHVARWLAGNGATGVLLAVRGEADTDALDA
LRAELSELETDVTVVVHDPADPSALTAAVDALPDGRPLTAVIHTGDDGAPAEGAGAPGAD
ALLAAVRRDLDALDAATGGRSLDAFVVFGSISGVWGVSGQGAGAAAGAYLDAVAQERRTR
GGNAVAVSWGAWAGAGPDGLAAHLRANGLPAMDPHRALTVLGTVVGDAVADPTAPASVTV
ADVRWDRFAPAFTRTRPGRLFTELPEVRRAPAAADGVRADAGTAATLRTRLRQLDERDRL
PYALDLVRTEVASVLGHAGADAVPAEQAFKDLGFDSLTAVDLRNQLAAATGLTLPATLVF
DYPTPTALAAHLLTGLLGEDTGPAAPAAHGTDAGTADDPIVVVGMSCRYPGGVRSPEDLW
ELAVAGTDAIGAFPTDRGWDLDRLLNGDRDGRGRSVTRHGGFLYDVADFDPDFFGISPRE
ALVIDPQQRIVLEAAWEALERAGIDPAGLRGGDTGVFVGGGSGDYRPAIGQVGHVETAQS
ASLLSGRLSYTLGLEGPSVSVDTACSSSLVALHLAAQALRNGECSIALAGGVTVMSTPVG
FVEFGEMGALSPDGRCKAFSDDADGTAWAEGVGMLVVERLSDARRNGHQVLAVLRGSAVN
QDGASNGLTAPNGPSQQRVIRKALTAAGLTAHDVDAVEAHGTGTALGDPIEAQALHATYG
QDRDPQRPLLLGSLKSNLGHTQAASGVAGVIKMVLAMRHGTLPKTLHVGTPSSHVAWDPD
AVRLLTEETAWPETGRPRRAGVSSFGASGTNAHVVLEQPTADADADADGTAPVPSAEETP
ATAGPLPVALSAVTRDALADQADRLRARLTDGADPDAAHCTDSVADLALSLGTTRSAFEH
RAVLVAADRAELVDALTALAEDRTGPDVLRGRAAPGGRTAFLFPGQGSQRPGAGRELYAR
YPVFAEALDAVAACLDPELDRPLREVMFAQEGTSEAALLDTTGYTQPALFALGVALYRLV
ESWGVRPDLLAGHSVGEIAAAHVAGVFTLEDACTVVAARARLMQALPAGGAMIAVRASEA
EVAARLGDRMSLAAVNGPDAVVISGDEDAVTALAEEFTALGRKTRRLRVSHAFHSLHMDA
MLQDFGRVTRSVSYTSPTLPLVSNLTGETAAPERVCDPGYWVEHVRRAVRFGDGVRTLAA
RGATRYLELGPDGVLCSLAQDTFDALADDNRPAPAAVPALRTGRDEERSLIGAVARLHAA
GQPLDWSALLDGTGARRVDLPTYAFRRRRFWPDAAPATPDTAPAADDGDAAFWSAVQDED
FDALAGDLGVDGESLSRVLPALRDWRRKRGDQSTVDGWRQRIAWRPLNRAATTGTPAGTW
LAVLPAGHDDDPWTAEVLGLLGPATVRLETTGADRADLAARLRELHDGDAPFTGAVSLLA
LAGGHDPQAPGTPRGATLTTALLQALGDARVDAPLWCLTRGAVAVSPGERVPAPLQAAVH
GLGRVAALEYPHRWGGTVDLPETLDERSAQRFAAVLADPEGEDQLAVRPAAVFGRRLAAV
QPGAPRDWQPTGTVLITGGTGALGAHVARRLAGAGARHLVLLSRSGPDAPGAGKLRAELA
ELGAEVTLTACDTADRAALAAVLADIPGHAPLTGVVHTAGVLDDGVLDSLTPERFEAVFH
AKVTGALLLDELTRNHDLDVFALFSSASAAVGNPGQGNYAAANAVLDALAERRRADGLPA
TSVAYGAWGGDGMAGDDRATALARRTGIRPLDPDLAVLALRQTVTGGDPVAVVADVDPER
FVRAFTTVRPSSLLAEMPAYAALTAAANTAGRDAERAAPGLRDRLTRLPGNRRLQTVLTL
VRERAADVLGHTGTDLVGPDRAFRDLGFDSLGAVELRNQLGAATGLTLSATLVFDHPTPA
ALAEHVLGELLPGDTPGGETTDENALRAVLASVSLDRLRELGVLEPLLKLAGRIPAAAGA
QAEGTGPEDVSDASIDAMEVDDLVQAALNGNLDDQRD
>A0A1Y2NIB4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces platensis|TrEMBL
MANEEKLREYLKRMTADLYETRQRLQDAQEKSHEPLAIVGMSCRYPGGVASPEDLWRLLD
SGGEGITGFPVDRGWDTEGLYDPTGRAEGTSYAKEGGFLHEAADFDPAFFGISPKDAPAV
DPQQRLLLETSWEALERAGIDPASLRGSRTGVFAGLMYHDYFGSTSSGSALSGRVAYHFG
FEGPAITVDTACSSSLVALHLAGHALRKGDCSLALVGGVTVMATPWTFIEFSRQRGLAAD
GRCKSFADAADGTGWAEGAGVLLVEKLSDARKNGHPVLAVVRGTAVNSDGASNGLSAPNG
PAQQRVIEQALVNAGLAPGQIDAVEAHGTGTTLGDPIEAQALLASYGQDRERPLWLGSVK
SNIGHTQAAAGVAGIMKMVLAMRHGVLPKTLHVDRPSTHVDWTAGAVELLAEAREWPRTG
QPRRAAVSSFGFSGTNAHVVLEQADAMAVVGTGVAAESGAEPAAEPVPNDGPVPWVLSAR
SEEALAAQAGRIASFAEGRPEATPADIGGSLVTTRSALEHRAVVLGADRDGLLSAARGLA
AGRRPAGVVADVVADGKLGVLFTGQGSQRAGMGRELYATYPVFARAFDEVCAAFDGRLPE
PLREVVHGAGELLDQTQYTQAALFALEVALYRLTASWGLTPDLLMGHSIGEITAAHVAGV
WSLADAATLVAARGRLMQELPSGGAMVSVRATEDEVRPLLAGEDQVGLAAVNGPGSVVLS
GDGDAVGRIAAELSSRGRKVKRLRVSHAFHSPLMEPMLDAFRAVAKGLTYAEPRMPVVSN
VTGRLATARELCDPEYWVRHVREAVRFHDGLLAGHAEGVTTFLELGPGGVLSAMGQDCLP
GHDTVRFLPALRENRTEPVALLEAVGGAYARGATVDWNPLLTGARRVELPTYPFQRRRYW
LDEADITGEPDRAAAADDARFWDLVARENLPELLHTLELDEDQPLGAILPALSAWRRRQE
HESTVDKWAYRISWKPVPTGAAALTGTWLLAGPDEDDRVAEALTAHGAHVVRLALGGSRE
ELATALAALDGEIAGVLARPTVTDALALVQALGDAGIGAPLWCVTSGAVSTGAADPLREP
ALAQVWGLGRTVALEQSDRWGGLIDLPAELDRTAAARLCAVLSGTGDEDQLAIRPAGVFA
RRLVRARLDRDAAPWKPRGTVLITGGTGALGAACARWLAANGAGHLVLTSRRGPDAPGST
ELAAELTALGAEVTLAACDVADRESLARLLDGLPEAPSAVLHIAGTGGPVVPVTELGGAD
LDGVLASKVAGAANLDALLGDRQLDAFVLFSSVAGIWGSGGQAGYGAANAYLDALAEQRR
ARGLTATSVAWAPWGGGGLAEDAAVQDQLRQRGLPAMAPELAISALAAALGQDETCLTVA
DVDWDRFIPGFTFVRPTPLFAGVPEARGLLSGGDGPAVADSALRRELAGLTDADRDKALL
DFVRIQIADVLGYDSPELVDPARAFKDLGFDSLSAVEFRNRLTTASGLTLPATMIFDYPT
PAVLVRHLRDEITDSAATPSATPSAVAASDEPIAIVGMGCRLPGGVRTPEQLWQLLAEGR
DGITPFPADRGWDTEGMYDSDPDQAGASYVRHGGFIDGLAEFDAGFFEISPREAISMDPQ
QRLLLEVAWEAIEAAGIDPATVHGTDTGVFVGANGNDYMSVLAGAGQGPDGFLGTGTSYS
VMSGRVAYALGLEGPTMTIDSACSSSLVALHLAAAALRSGECSLALAGGVTLMTTPGSFI
EFSRLRGLAPDGRCKAFAEGADGTNWGEGVGVLLVERLSDAVRNGHPVLAVVRGSAINQD
GASNGLTAPNGPSQARVIRQALTAAGLQASEVDAVEAHGTGTRLGDPIEAQALLSTYGAE
RDADRPLWLGSVKSNIGHTQAAAGVAGVIKMVLAMRHGLLPQTLHVDAPSTHVDWSSGAV
ELVTAPRTWPELDRPRRAGVSSFGFSGTNAHLILEQAPDLPAPPVDDVVADGPLPWVLSG
KTPQALAAQAARLAEHLTATPDTAPGDLAWSLLTSRSAFEHRAAVIGTDLDDLRRGLAAL
ASGATGAEVVTGTATTGALAVMFTGQGAQRVGMGAGLHRRYPVFAQAFDEAAAELDRWLP
RPLRDIVWAEPGSPDAALLDRTQYTQAALFAVEVALYRLLESWGVRPDRLVGHSIGEVVA
AHVAGVWSLPDACALVAARGRLMQELPAEGAMVSVRTTEDEVTALLAGREHEVGIAAVNG
PASVVISGAEKAVLEVAETLAAAGVTTKRLAVSHAFHSPLMEPMLDAFRQTVAGLAFRPP
RMEIVSNVTGRPLTAEEACSPDYWVGHVRGAVRFCDGVRALEAAGVRTFLEVGPDGVLSG
MGQECVTGDDTVLVPTLRRDRAEDGAAVTALARLRLRGVPADWTAFFSGRGVRRVDLPTY
AFQGERYWPRPSGTAGDVTAAGLGAAGHPLLGAAVAVAGSDEVLFTGRIGTHSHPWLADH
AIGDLVLLPGTAFVEMAVRAGDEVGCGLLEELTLAAPLALPARGAVRLQVVVGAADEDGR
RSLSVHSQPESDAAGQDWTQHATGVLAPAGAPGGYAETVWPPAGAEPVDTADYYPQLAEA
GMHYGPVFQGLRAAWRRGEEVFAEVALPEAAAEDAASFGLHPALLDAALHAAGLGAFFTD
EGGARLPFAWSGLTLHAGGAATLRVRIAPAGTDAVSVAAADETNTPVATVESLVLRRQDP
AATVAAPPLPDSLYRIDWPAVAAEPDGTTAWATLGTLDEAPETAVRYADLAALTAALDTG
TPAPEVVLVPCVGDTRADELPVAIRELTGRMLELTRDWLADDRLEHTTLAVVTRGAVAVH
ADEGIADLAAAPVWGLLRSAQSENPERIVLIDSDGSGGPDALAAALGSGEPQLAVRAGEL
QMPRLASLASGGTLVPPARGPAWKLDVTSAGTFDNLALVPSDADRALVPGEVRIGVRAAG
LNFRDVMIALGMYPEKAAMGIEAAGVVLETGPDVTAFAPGDRVIGMFAGAFGPVAITDSR
MLARIPDDWSYVRAASVPIVFSTAYYGLVELGGLQAGESVLVHNAAGGVGMAAVQLARHL
GAEVFGTASAGKWDTLRASGLDEEHLASSRDLDFEEKFRRTTGGRGMDVVLDALAREFVD
ASLRLLPNGGRFLEMGKTDVRTPEDVAAAYPGVEYQAFDLMGAGPQRVGEVLREVVRLLD
SGALRPVPVTTWDVRRAPDAFRYLAKARHTGKIVLTMPETLAEGGTVLVTGGTGTLGGLA
ARRLVREHGVRHLLLTSRTGRAADGAPELESELRALGAEVEIAACDAADRTALRELLDGI
PADRPLTAVVHTAGVLDDGVIGSLTPERLDTVLRPKVDAAVNLHELTAGQDLAAFVLYSA
AAGTFGGAGQGNYAAANVFLDALAAYRRANGLPGTALAWGLWTETSGITRHLGEADVRRM
SRAGMPPLSTEEGMTLFDAALRADEPAMLPARLDVSVFRGAPAEAVPPLLRGLVRTPARR
TVAAATRSADDFAQRLTGLTAEEIDGVLLDFVREQAAAVLGHGSPASVEPGRAFNEMGFD
SLTAVEFRNRLNGAAGLRLPATLVFDYPNADALAAHLKETLAPEAADPAAVVLGELERLE
SALAGLSPDEGAGASITSRLQALTKAWEDRRSTAGPTDVKDRLQAASTDEVFAFINDELG
LS
>A0A0N1NXA8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OV450|TrEMBL
PAARRNGHRVLAVIKGSAVNQDGASSSMTAPNGPSQQRVIRSALENANLTVADVDAVEAH
GTGTRLGDPIEAQALLATYGQGRDEDKPLWLGSLKSNLAHTQAAAGVGGVIKMVQALRHG
VLPRTLYAEDPTPHVDWTAGNVKLLTEPVAWPAGERPRRAGISSFGLSGTNAHVIVEEAP
AAETAEAEAEPRALPLVPVALSGRTPKALAEQAGRLHAHVTGHPDVSLTDIGFSAATTRT
PHEHRAVVVGADREELLAGLAALAEGTATGAVQGVVREGRSAFLFTGQGAQRPGMGRELH
AAFPVFAAALDAVVAAVDPYLDRPLYEVMWGESAGDEALLNSTAFTQPALFAIETALFRL
VESWGVRPDFLAGHSIGEITAAHAAGVLSLEDAARLVTARGRLMQALPAGGAMAAIEATE
EEILPHLGDTVGIAAINSPRSIVVSGTEEAVDAIQAQFTELGRKSTRLRVSHAFHSPLMD
PALAEFRAVAESVTYAPAQIPVVAGVHGELSEDWGTPEYWTRHLREAVRFSDTVQHLHAK
GVQTFLELGPDAVLTALTRTTLDGGDAVAEPAVRKNRPEARTLLTALARLHTTGTPVDWA
AFHAGTGAQVVALPTYAFQRERYWMTAELAGGGDASALGLAPADHPLLGAVITSPDTDGV
TFSGRLAVDAQPWLADHDVLGAVLLPGTGFVELALYAGEQVGHTTLEELILQAPLVLPEH
GGVALQVSVSGADELGRRTVLIHSRPQDATPETPWLLHAQGLLGTAPVAPGADLTAWPPA
DAAEVPLDEAYALLQERGYHYGPVFQGLQAAWRQGDTVFAEVELPEQAHEDAARFGVHPA
LLDAALHGSLLDDGSGDTTGGSAGSGVLLPFAWKGVRFHAVGATRLRVRIAPSGPDSITL
DGADAEGLPVFSVESLVSRAGAAADAAGQAAPGGSLFAVELQPLAAAAAPAPLTWGRWEA
DDRTGPAQDVLVLDVLDDFDAFGDLGAATAGGTAARVHAATARALARVREWLADERFAES
RLLVVTRGAVAAPGEGVTDLAGAAVRGLMRSAQAENPGRIVLADLEPGSTGLTVDPAVLL
AAAEPEVVVRGGALSAPRLVRATSSATADETVRFDGPGAVLLAGGTGTLGRLVARHLVTE
HGVRELLLAGRRGPEAPGAAELHAELTALGAEVTLAACDLADPDQARDLLARHPVSAVIH
LAGVLGDVTIGSLTPELLAGALRPKVDAAWNLHELTRDRDLTAFVLFSSVAGVLGNPGQG
NYAAGNAFLDALAAHRRAEGLPGQSLAWGLWATEGDGGSVSGDGMAEELNSTDLQRMRRS
GIGALSAADGLALFEAATTAADSVLLPLALDLAALRAADDLPAQFSALVRRRARTTARTA
ARAATQGGQLAALPEKERRRALLDLVRGQVASILGHSSTAEVGPDRAFNELGFDSLTALE
LRNQLTTATGLRLTPTLVFDHPNAQAVAEHLDTLLAGSAATATATAAATAGPAAGDDDPI
VIVGMACRYPGGVRSPEELWSLVEDEVDAITEFPVNRGWDIDGLYDPEPGTPGKVYVRHG
GFLHDADEFDPAFFGMSPNDALTTDPQHRLLLEVAYEALERAAIDQASLKGTSTGVFAGI
MYHDYTGNSAAGSLGSGRVSYTFGLEGPSVTVDTACSSSLVALHLAAQALRSGECPLALV
GGVTVMSSTETFVEFSRQRGLSKDGRCKSFSAAADGAAWSEGVGVLVIERLSDARRNGHQ
VLAVLRGSAVNQDGASNGLMAPNGPSQQRVIRQALANAGLSTADVDLVEAHGTGTTLGDP
IEAQALLATYGQDRGDAEPLWLGSIKSNIGHTQAAAGVAGVIKVVQALRTGIMPKSLHLD
APSAQVDWEAGAVRLLDEARKWPESDRPRRAGVSSFGISGTNAHVILEAPALPQPPSEAA
PGSPAAADAVGASAVPSASGTPAAADGPAASAGAAGAAARVVPWVLSARDPEGLARQAGR
LLGHLDTLPAAEPRDVGFSLATTRAPMEHRAALIAGDPAQARQALAALASGAPAAVPAVR
AATGGLTAFLFSGQGAQRPGMGRELHAAFPVFAEAFDAALAELDRHLDRPLREVVWGEDA
TELSRTVHTQTGLFAFETALFRLLESWGIRPDFLAGHSIGEIVAAHVSGVLSLADAAKLV
AARGRLMQALPEGGAMLAVQASEDEVLPLLTDAVSIGAVNGPQSVVVSGAEGEVEAIREH
FTALGRKTSRLRVSHAFHSPLMDPMLAEFGTVAAALSPAEPRIPLVSNVTGRIMTAEEIA
DPQYWVRHVRGAVRFGDGVRALAEAGATAFVEVGPDAVLAGLGPACLAGTDTGTDTGTDT
GTDTGTGTPVFLALSRRERDEEHTLVAAVAQAHTHGVDVDWRAFFAGSGAQRIELPTYAF
RRDRFWALDERRGGDAGSLGLDAVDHPLLSAVVPAPGTGGATFTGRPARTAQPWLEDHDL
LGTVVLPATGFVELALRAGAEFGCDRLAGLTLHAPLPLPEQGGIPLHVVVGAPGEDGLRT
VSVHSRAEDPDGDADSGWSLHAEGTLTAAAFSAPADLSAWPPPGAAPVAVADAYERLLAG
GYGYGPVFQGLQAAWRRGDELFAEIALPAGAGSGEAAADRFTVHPALLDAALHLDRLDRL
DTGAPAPLATASWTGLQVHRSGAAALRVRITRDAQDALALEAADEEGRPVLSAAAVTQRT
VPAHELRTGEQPGALYRLTWAQAPAGTTVQDAPVLFECPVPEGAADADAAARARTVAAAT
LARLAQWLDEERTAPLTVVTRGAVAVREDEGADLAQAPVWGLVRAAQSEHPGRFVLADLD
DTEASRQALPAALGSGLTEFAIRAGTVLVPRLVKAAAPDADRPSLASGTVLVTGAWSAAG
AAVARRLVTEYGATRLLLTRTDAAAAPDGAAAPDGLAGLDADTVVADCDPADRTARAALL
AGIPAEHPLVAVVHADLPAGTARIDAQARAGLDTDLRRSADTAWNLHELTRGDRLAAFLL
VSSSAGLMHGAGQGPLAAAAGFLSALARHRHGLGLAATALAFGPWEAAGATAEQHALSAS
LGLPALGADRGLELLDEALRTAEADLTALDPDRGTLRSATGRVPAVLAGFVRTPAGRPGR
GGADEADQLRRRLTGLDPQERERVLLEVVRSHVAGLLGHASADAVAADQSFQELGFDSLA
VVELRSRLGTATGLALPASLAFDFPTSRAVAGYLAAAVQPDGDDGTQAVAEALDQLDAAL
AAVAGDAADPTRITARLEAVLRRWQDTRTTEPTGPEQDFEAVTDDELFEALDRELGL
>A0A178X5M0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Amycolatopsis sp. M39|TrEMBL
MNGQTMSNEDKLRDYLKRATADLKQARRRLHELEARDTEPIAIIGMSCRYPGGIATPDDL
WDVVDEGRDVIGEFPADRGWDIEGVYDPTPERPGKTYTRHGGFLYDAANFDAEFFGISPR
DARRADPQQRILLEASWEAIERAGLDPHALKGSPTGVFAGVMYHDYSGGSPEGSLVSGQV
SYTLGLEGPSVSVDTACSSSLVALHMAAQGLRRGDCTLALVSGVAVMGTPEMFVDFSGRR
GLAADGRSKSFSDDANGTSWAEGVGVLVLERVSEARRNGHQILAVLRGSAVNQDGASNGF
SAPNGPSQVRVIEAALADAGLSVSDVDAVEAHGTGTALGDPIEAQSLMETYGQRTTGEPL
LLGSIKSNMGHPQAAAGVAGVIKMVQALRHARLPKTLHVGTPSRHVDWTAGAVELLTESR
AWPEVNRPRRAAVSSFGVSGTNAHVILEQAPVTETAEPAAAPVYPLVLSAKTPAALAAAA
GRIASHVDGQAGELADIAHTLATGRARLDHRAVVVAQDREQAAEALRALASGASRPDVVT
GTADARGKTVFVFPGQGSQWTGMATALLEQSPVFAERMAECDAELRKFADWSVLAVLRGE
SGTPPADRVDVVQPMLWAVMVSLAALWRAHGVEPDMVIGHSQGEIAAASVSGALSLEDGA
RVVALRSKAIGDVLGGRGGGMLAVGLPASGLGSRLDAWDGRISVAADNGATSAVLSGDGA
ALDELRDQLVAEGFRAKRVPVDYASHSAHVEHLADRLLADLAPIAPGAGTVAMTSTVTGE
PVAESTVDARYWFTNLRTTVRFAPVVAKLADAGYPRFIEISPHPVLAMSIQETLDEGGHN
GSVTGTLRRDEGGLTRFATSLAEHSVRGGAADWASLVPGARLVELPTYPFQHKRFWHEEE
AAAVPATGAQVADQDFWQDIAAGDVDALAARLGVEAAPLAEVVPALAAWHGRRTDLSTIE
SWRYRVSWAPVSVAGELAGTWLVVVPADVPEAAELADALAAHGDVVRVIATADREELAGL
LTEATALRPFDGVLSLLALDTREHPEHPALSTAVAATVALLQALRDNEVDVPAWVVTRGA
VAVDAFSDADPAAAAVWGLGTVVALDQPSTWGGLVDVDGPADAARLAAVVSGADSEDQVA
IRPSGVFARRMVRAPLPATEAEWQPRGTVLVTGGTGAVGAHVARWLAGRGAEHLVLTSRR
GLDAEGARELVDELAGTRVTVAACDVTDRQALAALLAEHPPAAVVHAAGVLTDEPALAEV
TPAEFAAATRAKITGAALLDELLGDTELDAFVLMSSGAAVWGTSGQPAYAAGNAYLDALA
RRRRAAGRTATAVAWGSWGGGGMVGAEASDLLRRIGLAEMAPELAAEALGQALDRDETHL
VVADIDWATFAPVYQLARPRPLLRALAEVAEDETGPVEDTGDLKGKLASLTPAEQQRTLL
ELVRGQVAVVAGYDNGSAVEPARAFKELGFDSVTAVDLRNRLGAATGLKLPATVAFDHVN
PRALAEHLWTRLGGGEAAVPLEAELDRLEAVASALDAAEIDRSRIVVRLQAMVTALHQTQ
AGTKAADVLHTATTDELFALIDNELGA
>K9VKC5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Oscillatoria nigro-viridis PCC 7112|TrEMBL
MTNSQENSELDGIAIIGMAGRFPGAASVGELWQNLCGGVESTAFFSDAELDPSIDPNLRQ
NPNYVKARGIIDGADRFDAAFFGVSTREAEITDPQQRVFLEIAWAALENAGCDPNTFSGS
IGVYAGTGNNTYFPNNIAGRSDVISRAGEFQVMVANEKDYIATRTSYKLNLKGPSVSVHT
ACSTSLVAVCQAFYALMSYQCDLALAGGISITVPQNSGYLYQEGGMFSSDGHCKPFDAKA
EGTVFGNAAGAVVLKRLEEAIADRDTIYAVIRGVGLNNDGAAKVSFAAPSVDGQADAIAM
AQAMAGVDPETISYVETHGTATPLGDPIEIEALTQAFALKTAAKQFCAIGSVKSNFGHTI
AAAGVTGPIKTALALKHRQIPATLHFEQPNPAIDFANSPFYVNAELSEWKAGKTPRRAGV
SSFGVGGTNAHVVLEEAPALEPSSPSRPRQLLLLSAKTPSALDAATANLRSHLAQNPEID
LADAAYTLQTGRQAFNYRRFAVCSDRTDAVEILESLPPLRTATRCTESRNPAVIFMFPGQ
GSQYVNMGLNLYESEPLFRETVDRCAEILQPHLGRDLRKVLYPGSDEATAAESLRQTFLT
QPAIFTVEYALSKLWQSWGIIPQGAIGHSIGEFVAATIAGVFSLEDALMLVAARGRLMQD
LPGGSMLSVRLPAAEVEGRLSADLAVAAVNAPDLCVVSGPTEAIALFQQQLESESVVCKQ
LHTSHAFHSPMVDSIVEPFAEYVKKVQLSAPTIPFVSTVTASWITAEQATDPMYWARHLR
ATVRFADGIKELWQEDPNRILLEVGPRTTAATLARKQAKDLKKQVAISSLSDSHENQTEW
AALLSAAGQLWLCGVSIDWQSFYQEETRDRLPLPTYPFESKRFWIEPKVSEDKSGRGGDG
ESERVGEWENSQFPMPDSQFPMPDSPFPITTSQLPTTNSQLPMPNSQAETQTAARKYRLI
PAIKNILEETSGEDLGSVDEDLTFLEMGLDSLSLTQVALNLQKEFSIKITFRQLLETFPT
LGTLSEFIDGALPPEVLPATPAVQQAAPVPAPAPPIAPPEQTAIPVPASAPVNLPLPSPG
PQILHPVQSGNLEYLIGQQLQIMSRQLELLGGAGSVPAQPAPTTNGRGSAPVPAPSQPAA
VQNIPQSQTHGSAIAPTAAPTAEPTAEPKKVFGAAARIDTSDRDGLTPQQSAYLETFVKR
YTARTQKSKQYTQTHRHHLADPRVVSGFNRTMKELVYPIVVGRSSGSKLWDEDGNEYVDL
TNGFGSNFFGYSPAFITEAIAAQMQRGYEIGPQTPLAGEVAELVCEMTKHDRAAFCNTGS
EAVLGAMRLARTVTGNSTIVMFTGDYHGIFDEVIVRGTKKLRSLPAAPGIPQSAVDNTLI
LDYGEPESLEILKARAGEFAAIMVEPVQSRRPDLQPREFLHEVRRITEQAGCAFIMDEVI
TGFRVAPGGAQEYFGVQADIGTYGKVVGGGMPIGVIAGKSAWMDALDGGFWQFGDDSFPE
VGVTYFAGTFVRHPLTLAAAKASLEYLKRGGPSLQRELNAKTDKFVAELNAMFDREQAPF
TVKNFGSLFKITYPQDFTHGELLFYSLREKGIHIWDHRPCFLTLAHSDADIAFAKEAFKN
SIAELQSAGFLTAPSGATVKVLEFNKNGNTNGSKSSTVFASNSPVPGAKLGRDPNGNPAW
YIADPERPGKHLQVGDSLSN
>L7EF42|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Microcystis aeruginosa TAIHU98|TrEMBL
MPKTQSDKIAHPIAVVGMGCHYPGANQLSELWENILARRCQFRQFPDQRLPLSEYYDPDP
ATPDKTYGTRGAFIDGFQFDWINRRVPKKTVDGTDIVHWLALEVANKAIEDAGYRRDTVP
TQKTGVILGNSLTGEHTRSNVMRLRWPYVRRALRAAAEVKGLSGTIVEELLETMEKFYKS
VFPPITEDTLAGGLSNTIAGRICNFFNFDGGGYTVDGACSSSLIAVVTAANALSNGDLDM
ALAGGIDISLDTFELIGFAKTGALTAQDMKVYDRRASGFVPGEGCGFVVLKRLADAQADG
DYIYALLDGWALSSDGKGGITAPSKVGQSKALLRAYEKAGYSPQSLHFIEGHGTGTPVGD
RAEIEGVALAMNASKPAPPRSCGMTSFKSLVGHTKAAAGIGGFIKAVMAVNQRIVPPTVN
CQEPNPVFEESAQCLYPVQLGEIYPETEILRAGVSAMGFGGINSHVTLSSGDAPSPRLKP
SLDQRSLLVSNQDSEIFVFGANSLAQLLEYLQIFSEQAKGMSLADMVDLAAQNAQTLSPQ
TSIRAAIVAENPRELLERLEHLINILHSQPPAAGETYISQRKDIWLAHQVQRSRVAFLFP
GQGSQKLNMARTLVERYSWARELVQQADLWLIESGFEPISPLIYRPLDRAVNQQQVEQWF
NALTDVAPQAICLTSLLWKHYLKRLGLEPVALGGHSLGELTAFEAAGAYDEKTLLCFAAM
RGKAMTVKGDSIGTMASLACSDATAQKLLQGISGYVTVANINSPQQTVISGEKTSVAAVC
DLALAQEIQVRQLPVANAFHSQMVAKAAEYLRKEAPIPEILEQVSLPLFTSVNGQIVNSG
LNLKEHFAHQIVAQVNFVSLVENLKNKCDLIVEVGTGKVLSGLVGAIVPSPLCFPLESKP
GIARDLNTFLAAYFVQGGEVNWQALYEQRLVRPFVPAAERLFVDNPCERSFPVSLEEIES
SSAFSWREIQQSSPNTALAHSSNFSQPESLFADDELTTVLANYLLERGSFLSELISADIQ
SLPFVNTHNA
>A0A1V6GH40|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Verrucomicrobia bacterium ADurb.Bin070|TrEMBL
MTGRRHLYDPFDCELCLVGAPDDTRLAEEVKRLIHFLEHAPDVSLQDVAYTCACSARSMP
AVLAVVAASVADLRDRLAQAHKKLSENAGRIRDKSGTYFFRDRLCPRGRIAFLFPGAVSF
YPDMLRDLCLVFEDCRGAFDELEEALQTRDTETFSPSDYIFPPAACYRNDAGAFSAQAFS
ESFIAVHAANTALFRLFDRMGVTPDGLAGFSGGDFAALEVAGVYGNLSRNKRIVFMREGY
QMLSRLAERDDLPACVMLSVIDAPRAMLDTLVEAYPGRLALAFFHSPRQQTIALSPSILK
EVTAVLHKAGVKTMTVPIDRPFNTPWCSKVLPPIKQFLSHWVRHVPKIPVYSCATAERLP
AQPRAIQHLTADQWTSPILFDDTIRQMHEDGFRIFIELGARGNMTNAIDETLKNHPHQAV
AINRVHRSGLVQLHHALGLLAAQGVQLDLTMLHRHRRSRSLDFNRPLSVVTRTENDLRLT
ARLPTLTLFAPPGEFLTSSRATSEQARKAMPVITDKRSFDFGADFPMLANATILEEEPGV
MMEIAKVLTLEDYPFLRDYALGTSQLSYAKPALKGLTLLSLISSLEMMCEAARKLVPRRR
VAQIDNLHAQRWVGFERGSLRVILRAERISWPDTHFTAVRVQLRDDSPNSAFTWPIVEAI
VLLTAAGPANHPIQPPPLANPRPVNWSGHDIYPDRLFHGESLRIVRHVDLWSEEGIDFEV
EVPGRADAVRYTKIPLFSIWPMLLDGIVSAFSLWRAHEKFAGAISMPFRARRIVFHANTF
TEGARLRGYLRLISVTPRSHVADIQVSDGNGNLLIHFRGWEELCERVPPEYHQFILRPSE
QYLTRDLPLEMLGNPATPVAASVATEVPFKIFENNQELWLKTLAHVLLAPVEREEWLEMQ
GATSRRVEWLFGRAAAKEAVRRFLVKYHQARWTDADIPIWPDDSGKPHPLGPWREHTAAK
IDLSITHTSKLIIAAVAANARIGIDVEVLGRALSDDFTRGVFTHEELELAAHTGEAPTAV
LRFWCAKEAISKALGTGIRYSPQDLRITAVDAMTGQLQIELLGQWLEPFKQFKGRKNPIH
TSLFEGHAVATCLLPASLFETPE
>A8M110|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Salinispora arenicola (strain CNS-205)|TrEMBL
MTRIAVIGMACRYPDAASPTELWENALAGRRAFRRLPDERMRLEDYWDPDPRTPDRFYAR
QAAVIEGYEFDRIAYKVAGSTYRSTDLTHWLALDVAAAALADAGFPMGEGLPRQATGVIV
GNTLTGEFSRANQLRLRWPYVRRVVAAALKEQDWDDARLGAFLEQLESTFKSPFPEVDED
TLAGALANTIAGRICNHLDLRGGGYTVDGACSSSLLSVATACKALVDGELNVAVAGGVDL
SIDPFEIIGFAKTGALASSEMRVYDQRSNGFLPGEGCGMAVLMRESEARAAGHRIYATIA
GWGISSDGRGGITRPEATGYRLALRRAYERAGFGIETVGLFEGHGTGTKVGDTTELTALA
EERAAADPHASPAAISAIKAMIGHTKAAAGIAGLIKAAMATHHEVLPPTLGCVEPHDVFG
AQSAPLRMLRKAEPWPSDSPVRAGVTAMGFGGINTHLVLENDRPRRRARFDSRTHALASS
MQDVELLLVDALSPQELRDRLQRLTDFVPSLAYAELADLAATLHGDLRELPWRAAVVVSS
PDDAVHRLNQLCAALDSGEAELISPDGRTMLGHASGPGKIGFLFPGQGSGRGTNGGALRR
RFAEAEQVYAQATLPSSGDMVATEVAQPRIVTGSLAGLHVLSALGIEASVGLGHSLGEIS
ALYWAGAFDSATLLRVAGVRGRTMAAHSSSGTMAGISASPEVAERIIGDRPVVIAGYNGP
TQTVVAGPVEEVDAVVRDAAEAGVSASRLNVSHAFHSPLVEPAADAFGELLTVERFNSLD
RRVISTVTGEGLPDQTDLKSLLRRQITDPVLFSQAIALAAKEVDLFVEVGPGRVLSGLAT
AATDVPAIALDTDNESLAGLLSAVSAAYVIGGQPVDSALFHGRLTRPLPVGTTFSFFANP
CEAAPTLPVPATTAATRPAEPTNDPIGAPTAGESTVDTMRRLAAERAELPLELVNPDSRL
LDDLHLSSITVGQVVNHAAQALGVPVAQAPTNFAVATVQELADALDSLVGTGESDAAPIA
AQVTGAAEWIRAWRVDLDDVPLSPRAGTETGGAWQVFAAPDSTFAEPLRRALERAGVGGG
VLLCLPSSCTTDELERALTAARAALAGGDRFVLVQSGRGAAGLAKTLHLEDPRVRTTVVH
LPEQTPTAVDTVVAEVAATTAFSETYHDPDGTRRVPTLRAMPVRATREQAALDQTDVLLV
TGGGKGITAECALAMAQDSGARLVLLGRSDPATDRALADNLDRIAESGIRVRYLRADVTD
AEQLAGALNSLPPEWGPVTAVLHGAGRNEPTSLNSLTMADLDATFAPKVDGLRNVLAAVD
PAQLRLVVSLGSIIGRAGLRGEAHYAIANEWLADATAEVGRQYPGCRALCLEWSVWSGVG
MGERLSVVESLARDGITPITPDQGVALLRRLLADPDTPPVVVISGRTEGIHTVRHDAPPL
PLLRFVERPLVRYHGVELVSEVELSSGTDRYLEDHLLDGNLLFPAVFGMEAMAQVAAAVT
GESGVPVIEDAEFLRPIIVPPAGSTTVRVAVVVTDDRTVDAVIQSAETGFGAEHFRARLR
YGGTDAPDGPPDQVAEGLPVVPLDPVQDLYGHTLFQGQRFQRLHRYHRSAARNVDAEVVV
PQRTDWFAPYLSAELLLGDPGVRDALMHGNQVCVPEGTLLPAGIERVWPGGGRIEAEEVL
RYAAVERSRDGDTYVYDIALRTTTGRTVERWSGLRLRAVRKRDGRGPWVAPLLGSYLERT
LGDLGASEVAVALEPDEPASGTPGDHVATRRGRTALAAGRALGRPVEVRYRPDGRPEVAG
ERGISAAHGAGMTLCVAGTGPLGCDVEPVAERSPADWKGLLGRYQDVADLIATRDRETAH
TAGTRIWAATESLRKAGYSTGAPLVLLPDDRGPWVTFTSGDVRIATLLTTVRDVPDPVVL
AALFAPTRRKVGSHG
>K9XDD7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Gloeocapsa sp. PCC 7428|TrEMBL
MLTQKQAPKIAITGMNLIAGSCQDLDSFERIVYEGKQNFIELPLSRWQGKAEQLLKENKI
ENNQVPLGGYLPFKIDEQLAIDNIEELNPQELLMLKVANNALQDAEIKPGEKVAVIIATA
TQISLQKLYSKQQFTRQLQTILAGKTTTNHSALATTNISQTQSEYRSPLENTIATRISAL
WQFEAPAFTLTAEENSAFKALEVAQNLLVLGEVDAVVVGAVDLAGSSESVLLRNQLAKIN
TGVPTLSYDENANGWIVGEGAGAVVLKLLDTAIASCDRIYAVIDAISLLPQHTTSAYDSA
AVTQVCQRAFQIADLYPQDIDYLEVHGSGVEAEDTAEIAGLLAAYQTSTELSCAIGSVKA
NIGHTYAAAEIMSLIKTALCLYYRYIPATPQWSRPKNPEIWQESPFYVATESKPWFSALE
KPRSAAINSISLDGSYAHIILSEDTSKKNLTRFYADSNRYLTQMPFYLFAIAAENQTDLI
AQLHALEQTIKDSNALTTAASQTFTTFQKQANAAYTLTLLGRNKDDLLREIQRAFTGVER
AFEQNGDWHSPVGSYFTTNPLGKKGAIAYVYPGAYNSYVGISRSLFRLFPQIYDDIVIKS
ACNRVANIEKLLYPRSLHKLSKRQLESIEQQLLNDPLAMLESEMGYAGLVTTIFKNYFQI
KPQCSFGYSLGETSMMFSHSVWTDFQECSNALNSSSLFSTRLAGSKDAVREFWGLPLVEN
PDEFWSTYVLITSVADVQEGIKQENQVYLTQINTSKECIIAGETQACLRFIEKLKCDAFR
APFNHVIHCEAMRSEYPELVRIKTLPVQKIPETIFYSSAKYAQIALNSESIAHHIAECLC
QQVDFPRLVNRVYADGVRVFIEVGAGSHCSRWISENLKGQEHVTVSVNRRGVDDHTSILK
ALAKLLSHQVSLDLSSLYARSLETSLEPQQESLSLTLPLNQAKSDDNQIELDSVENSAVV
NKNIVIEQVPMQVLQRDNTTISVEAIPTSAETIKVIKQTNPVIPLVSQQTVLPKRNHCLE
DNNTYLKLKENNQRTTQIHTQFLQARQKALQQMSRMIQLQMNYSQLVTQDINTNPPVSKP
VSLSIS
>A0A1Y5PEH6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|uncultured Mycobacterium sp|TrEMBL
MLSIVSEKTGYPVDMLGLGMEMEAELGIDSIKQVEILAALQAKFPGAPEIPASELANLRT
LQDVVDTVSGFAAGGRTEQGAAVQQSAPESVAPVGLSCTEAELRAAPPSGLAMAGLRDGV
VFITREDPAFADALERALNARGLQAKTVEEAPAEAGAVISLAALAPACTPDDCVAVHVRA
FHAARSVAKSSARTRLFVTVQSTGARFVAADVPLGVASLVKTAGWEWPNASVRAVDMETL
DAERLAAELLEGGSGIEVALRADGTRLVAVDDIESSVGEGETISVAPGGVVVVTGGARGV
TAESALALAKQHGLRLALLGRTPLREVTADEPSGATSAEIATALAASARARGEQLSLPQA
RAQAESLLATREVRTTLASAENQGTPARYFAASITDEAALRSVLNEVRQNFGPIVGVVHG
AGVLADKRLEDLDDDGFVKVFTTKLIGAEALLDATSTDELRFISLFSSIAARAGNPGQAA
YASANAALEAIAARESARRNGECVVRAFGWGPWDGGMVDATLKSRFLAGGVGVIPIAEGA
QFFAEHALCRSSASAVVVAAPAEPRLRAARLDWEVSAENLPVLTDHQVRGRVVVPVVIAL
DAILRAARGLLADACPVVRDFQVLSGVTFAEHERQSLTIDFEPAGSSYTVSISDADGRAR
YRATVDTAAVASPELSVPQVSGSAWPLGVDEAYAGPLFHGPQFSVIEQLDAFGTAGGTAT
LKSLGDLDWPQSGWAIDAASIDGGLQLGIVWASAQGRPLVLPVRIGRVVLHRAFGDGSIG
RCRLAAHPVNDKRVDFDIAYETSDGALVATLEGVEFYAAGTAADTSA
>A0A3N6FZM4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI98-12|TrEMBL
MSSEDKLRDYLRRVTAELQVTRRRLREAESRSAEPIALVGMACHYPGGVESPEDLWSLVA
EGRDGITGFPRDRGWDVDGLYHPDPDHPGTSTVRDGGFLHDAPAFDAGFFGISPKEALYT
DPQQRLILQTSWEAVERAGLDPAALRDTCTGVFTGVMHHDYHGAQGGGSVVSGRVAYQLG
LRGPAVTVDTACSSSLVALHQAVRALQRGECDMALVGGVTVMATPSAFVEFSRQRGLAPD
GRCKPFAAAADGTAWSEGVGVLVLERHSAAVAAGHRVHAIVRGVAVNSDGASNGLTAPNG
PAQRRVIQDALVDAGLTPAQVAAVEAHGTGTPLGDPVEAQAVLAVYGGDRPRPLWLGSIK
SNLGHTQAAAGVAGIIKMVLAMRHGVLPRTLHLDRPTPYVDWSAGAVELLAEPVPWPAGD
EPRRAAVSSFGVSGTNAHVILEEPAAATPAPGTEPAASWPCAWAVSGRAPAGLRAQAAAL
AADLAARPDQDPRDIASSLVTTRTAHEHRAVVCAADRDGLLAGLADVAAGRPSPTVVEGV
TGAPGPVAFLFPGQGSQWREMAVRLLESNTVFRDRIAECEAALAPYVDFELTAVLRGEQD
YDRVDIVQPVLFAMMVALAEVWRSVGVTPAAVAGHSQGEIAAAYVAGALTLPDAARVVAL
RSQALVELSGLGGMMSVALPAEQVRERLRAWDGRLSLAAVNGTASVVVSGDGDALDELLA
ELEAEEVRARRVDVDYASHSAHVERVQDRVRAALAPVVPRPPAVPFFSSVEGRWIDGDDA
FDADYWYRNLREPVRFDEAVTALAGHGCTTLLEVSPHPVVATGAQETVDAIGAEVAVLHT
LRRDEGGPDQLVRALAQLHVQGVRPDWSAVWPGARPVELPTTAFVTERYWLPAGGGDPSA
LGLDAVEHPVLRAAVPGADRLVLTGRLSAATHPWLADHTVEGHVVLPGAAMVDLVSRAGD
EAGCPVIDQLTLLVPVVVPEDAEVRLRIEAGEPGTDGSRDVTVQGRVGAGNWTLHATAVL
TPGGDPPPPAATAWPPAGAEPLDVDELYARLDSAGLRYGPVFCGVRALWRDRAGDLYAEV
ALPGAEPDGFGIHPALLDACLHPLALSDLRTGAQDRPALPFEWTGVQVHAVGADTVRATL
TGARDGAVRIELTDPAGTPVASVRSLALSPLPDGALGLPDRGDLLLPQWAPLTLPDGPAA
GYAVRDPALARLLRVSPSDDVAPFILVPAPSGPPAAAAERALALVQEWLADESRATSTLV
VVTRRLLDDPGEAATAALVRCAQLEHPDRFAVLDLADDDDATVAAVPAALAAGEPQVGLA
AGAARELRLVRVSPTGEPAGDLGTVLVTGASGTLGGIVARHLVHDLGVRDLMLASRRGPQ
APEAATLAAELTAAGAHVAVVACDVADRAELTELLGTTTVDTVVHAAGVLDDGLVADLTP
ERLARVLRPKVDAAWLLHELLPQARLVLFSSAVGVLGGLGQANYAAANAALDALARVRRA
AGLPGVSLAWGLWADESAMTGGADLARFRRSGFPPLPRDAALAALDAALTVAEPVLVPIR
LDLAALRATGDAVPPVLRSLAGAPARRTVTRGGAADSELVARLAGKSPADRHRVLLELVL
GHAAAVLGHASPDTIDPDRAFKDAGFGSLSAVQLRNRLSGATGLRLPVTLVFDHPNPAAL
ARHLADRLAGAERPSAAPVTAGTADDPVVVVGIGCRLPGDVRGPDDLWDLLVSERDAIVP
FPDDRGWPLAQLHDPDPDAPGTSYTRSGGFVSGAAEFDAAFFGVSPREAVAMDPQQRLLL
ETVWETCEDAGIDPDTLRGTGTGVFMGAMYQDYGRLLEGAAAEGFLAPGVGGGVLSGRVA
YTFGLQGPTVTVDTACSSSLVALHLAAQAIRAGECDLAFAGGVTVLATPAVFVEFSRQRG
LAADGRCKPFAAAADGTGMGEGVGVVLVERLSRAREHGHRVLAVLRGSAVNSDGASNGLT
APNGPAQERVIRAALTAAGLGPADVDAVEAHGTGTVLGDPIEAQAVLAVYGGNRPRPLWL
GSVKSNLGHTQAAAGVAGVIKAVLSLRHGVLPRSLHIDEPSPHVDWTAGEVALLASAQPW
PRHEAPRRMGVSSFGISGTNAHVVIEEAPPAPDAEEERPVLDGVPWLLSARSEAALREQA
ARLAATAATDPSAVAYALATTRAVHKHRAMVTGADETALRTGLAALAEGNTVPAVLRATA
ARHRLVLVLTGQGSQLPGMGRGLYETFPEYARAFDEVSAHFTLDTPLQEVVWGDGSLLDR
TEYTQPALFALQVAQFRLVSAWGLRPEMLIGHSIGELSAAYLAGMLTLDDAATLVTARGR
AMAGLPAGGAMVSVRAAEAVVLPLLAGYADRVSIAAVNGPDAVVLSGDEDAVLELAGVLS
DRGHRTRRLRVGTAFHSARVEPALAGFRAVAEAVTFQQPRIPIVSTVRTDEKMISPAYWV
DQLRGSVRFLDAVREADRAGGTAFLELGPDAVLAPAVRACLPEVPVPPVALARRDRPDVR
AALGALGALHTYGVRVDWPAVYAGREPQRSPLPRYAFQGRRYWPELVPPAPVPAPRPASD
ALWSALGSGDPAAALSMLGLRGDETPHQVLAAVARLRPGAGTTRRPVRWRLVPDAAPPVL
DTTVALVPPPGDDPELTDALAGALARHGARVTVDATERPDLVIVLPGAEPAGMPGVPLWV
LTRDGSLPVADHVVDLPPEMDARARARLCAVIGQGHTAARIRPEGVFVAEYADEDPADPA
LLDEAVTEPPAGVEPSVASVRSGPSGGLRAALARLPRDRWDAEVLTGVRALAAAVLGHDS
GAEIGADDEFFDLGLSSVTALELRDHLGALTGLEWAADVLYECPTPQALADLVVARMNEE
E
>H8FPU6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Magnetospirillum molischianum DSM 120|TrEMBL
MGASISEIAQHRADDPVCIVGLGCRLPPDTESAEAFWRFLRQGGCAVRPVPPERWTAADY
AANGPARPGTSVSRWGGFLDGSFPAGFDAGFFDIAPAEAQGLDPQQRLLLEVAWSALEDA
GLTPERVADDGNVGIYVAISTSDYQGARIWNSDLAGIDAFAATGAAFAAAAGRLSYTLGF
EGPCMAIDSACSSSLVAFHQACQAIRAGECDAALVAGVNALLAPNLFVGLTQLGVLSADG
RCKAFDAGGDGYVRAEGAGALLLMTLSRARARGCRVLGLVRGSAVNQDGKSNGLTAPRRS
AQEAVIRRAIARSGLSFADIGYIEAHGTGTPLGDVVEMAALAATYGVGRDPADPLLIGSV
KTNIGHLEAGAGIAGLIKALLCLRHGEIPPHLHLSSPSPHIPWEQYPFRVPTVLTPWPAG
DKPRRAGVSSFGFSGTNAHVILEEAPAESARADGPTAPDPQVLPLSARSPDALRALTERF
ADYLESTTAPLSDIAHMAGVGRSHFGFRLAAVGSSGAEIASGLRQSLAGAAPRSVSVGSK
SERPRIAFLFTGQGSQYVGMGRSLYRDQPVFRAALDACDAILRGRLGESLLDLLYGPQAD
NERLQQTRFAQPAIFAVEYALAELWRSWGVTPDIVAGHSIGEFVAAHVAGVIGLEDALTL
VAERGRLMQSLPSGGAMASVAAPEGVVSAAIAEAVKAGALVSVAAINTPEDIVIAGPADR
VADLRRGFEAQGYRTQELRVSHAFHSPLMRPMVDVFAEVAAGVSYRPAHLPMVSTVSGRK
AEAGDLSSAGYWSAQVEAPVRFASAARTLAEDGVTLFLEIGAAPILTALARTNVESDKRV
FLPSLMRPSGANPDATTDHRTLAAAVAALYAQGAEIDWDGRDKPFDLRKVAIPGYPFQRK
SYYVSPVRGGVTVSVPTAAAIDPVPRVPSDPVRPVVPGGGRDGLIRTIDEIARRVLSDQP
LPPLDSDRALGEQGFTSLMALELRRQLDLAFQSRLPATFFFNYPSICRMADYFLAHDDPP
PPPPVGSTPHAAPPDAFPDSSGFRFLDDLSPSELEQLIEREVNLL
>A0A3N6EBY0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-17|TrEMBL
MELDWEAVFAGQRATHVDLPTYPFQRQRYWPEALALPDAGVVDPVDAQFWDAVEQGDLAA
LAATLDLEEVPDSPLGEVLPALSSWRRQRRENAAADSWRYRISWKPLAENTASLSGTWLL
VAPGTGAGGDAGDAVEAVAEGLRGLGVDIVQCAPGDVLDRAALAGELTGALGGRTAVEGV
LSMCALDEEPVPGLPEATAGLAATLALTQALGDADVTAPLWCLTRGAVSTGPADGAARPA
QAQVWGLGRVAALEHPDRWGGLIDLPEVLDERAVARLGALLAAGGDEDQLAVRSAGVLAR
RLLPAPATAAGRAWEPEGTVLITGGTGAIGARVARRLGGSGAEHVVLIGRSGLRAPGVER
LRDELAGTGVRVTVAACDVADLDELTALVGKLMADGERITAVLHAAGELDDGVVDALTPE
RLARALRAKAAGARNLHEATRELDLSAFVLFSGVAGTVGGAGQGAFAAAGAYLDAFAEHR
RDLGLAATSIAWGPWAEGGPALDDDTFLERTSRRGLAALPTESALTALFRAVAQDGPAQL
VADIAWDRFGPALTAARPSPLISDVPQMREIARAAEQAGDTGADDAAEFRRAVAELSDVE
LGQMLLELVRTEAAGALGYTDIEAIGPKRPFRDLGFESLTAVELRNRLSTRTGLRLPVTL
AFDHPTPVVLAAFLKGEAGRDAEPQTVPVLAELDRLEASLATLSADRTARHRIAARLRDI
LAGWDDEPAGGDGATVTEKLESASADEVLAFIDNELGAS
>A0A4P6Q7E6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomonospora litoralis|TrEMBL
MTAVDNDTAVAVVGISCRLPMAPDPQRLWQVLREGVDAVGEVPPGRWDDGRELAGFVGRG
AFLDDVEGFDAPFFGISPREAAEMAPQQRLSLELVWEALEDLGADVRGLTRAGLYVGAMD
EDHTVLRSGAAQAGITPHTATGSARSMIANRVSYALGLDGPSMVIDTGQSSSLVAVHMAC
ESLRSGENDVAVAGGVHLNLSGRVTAEMGAFGALSPEGRCHTFDERADGFVRGEGGGFAV
LKPLRAALADGDRIYGVLSGSAVNNDGGGDGLTAPSADSQARVLRSALSRAGVSPEAVGY
VELHGTGTPAGDPVEARALGEALGAARGSEGPLPVGSVKTNLGHLEGAAGIAGLLKAVLA
VHHGELPPSLNFARPNPAIPLEGLNLRVATDREPWSAAPVAGVSSFGMGGTNCHVVVTAP
PEAPDRPAEPGRRPAAVPWVVSGHNPAALRAQAARLADFAAADADADAAADPADIAYSLL
TARTPHAHRMAVCGGDRDELLRGLRAYADGAPSPGAVEGRTADGATAVLFTGQGAQRLGM
GRGLHAAFDVFADAFDALADRLDERLEHPLREVVWAEPGSPRAHLLDETVYTQCATFALE
VALYRLFEHWGVAPGHLLGHSIGELSAAHVAGVLDPDDACALVAARGSLMQALPATGAMV
SVQAPESRVAPLAAERAGAVDVAAVNGPSATVIAGEREAVEEIAARLGEEGVKTRRLRVS
RAFHSPLMDPMLEEFRLVAAGLDYREPAVPVVSNVTGRPVEPGEITGPEYWVRHARRAVR
FLDGVRTLERSGVTRCLELGPDGVLAAAAREAYTSPAAFTPALRRDRDEARTAVSALAEL
HVHGETPDWEAFFGGGARRVPLPRYAFQRRAYPVPTGPRQPTAAPEPGPAPTAADTGEPA
EPVGAGTPESAPPAPADPLALVRAHTAALLGYDGPDDIDPGLAFKDLGMNSLTAVELRDQ
LARATGADLAGSLVFDHPTPAALAAHVAAGGAQQVPAAPRSTAPSAAEPVAIVAMACRFP
GGADTPERLWELLEEGRDAVGPFPDDRGWDLGALLDSDGGRGGTSSTREGAFLGDAPEFD
PEFFGVSHREAAAMEPQQRLLLETSWEAVERAGIAPDSLRGSDTGVFVGAMPQKYGPPEA
EAGEDVAGYLLTGTTTSVASGRIAYTMGLEGPALSVDTACSASLVAIHLAVRALRNGECS
RALAGGATVMSEPGIFAELSRQGALSPGGRCRSFSADADGTGWGEGAGVLYLERLGDARR
RGHRVLALLRGSAVNQDGASNGLTAPNGVAQHRVIRQALADAELEPGDVQAVEAHGTGTR
LGDPVEANALAATYGSGGEGDAPVWLGSLKSNVGHTQAAAGVGGVMKMVLALGRGTLPQT
LHVGEPTPHVDWDASRLRLLTEARPWPEAAGPRRAAVSSFGISGTNAHAILEEAPAEAAA
EDGAAGAEAPEDGAEAAESAAPAGPLDAVPVVLSARDETALRAQAGRLREHAAREAPDLA
DLGSALLTTRTAFRSRAAVIAADTAELLDGLAALEQGHGTVEPVLGTAPAEAPRTAFVFP
GQGSQWPGMAAELWQAYPAFAAELESCAQALRPFVDWEPMDVLLERPDAPPLSRVDVTQP
ALFATMASLAALWRAHGVEPAAVVGHSQGEIAAAYVAGGLSRRDAARVVAMRARAWWELR
GQGAMLSVALPADEVRERLHRFGDALAVAAVNGPGSAAVSGTSAAVEELLAELTAEGVMA
RRIPDVDVPGHSPQVEVLRDRLLEDLAPVAPRTSDVPFYSTVTGGLLDTAGLDAHYWYRN
VREPVRFHDAAGALLDAGTGAFLEAAPHPMLAVPMRETAEEHRRPATTLATLVRRDGGPR
RFLTALAEAHANGVGVDWERVFGRRRPVDLPTYPFQRRRYWLTPPQRTGDVSAAGLVPES
HPLLAAGTVLPATGELLFTGRVGADDHPWLADHRVRGSAVAPPELFVDLALHVGGQVRCD
VVEELTVERPMPVPEAGALTLHVLVGPADDSGHRLLRMYARAAGAPEADWTLHARGVLAD
EEPAAPEPADRLGGTPAEGPDYAGLARHGLSLGPALQTVTRARRSGAELEAETALGETGG
AGAADAPFVLHPALLAGAVHAHRCEAGPAAMATSWRRVAVFAAGAESLRVRITPAGPDEA
RLVAVDGQGRPVLSAASVAFTEPGPEWSRAAAAPGTDALFRVSWVPRRDLTEAAEPPATA
PLRYDPAGRPPDLAEATRLALHDVLGPLQEAAAGEDRLAVVTRDAAAVGDGTAADADPVA
AAVSGLVRSAQAENPDRIVLADVDGTPESEAALDAALRCGEPEFALRGGVMYVPRLERTA
AGPPAPPPGEGTVLITGAAGTLGRLCARHLVAEHGVRRLLLASRRGEDADGARELAAELA
EAGAEVRWAACDAADRDRLAELLASIPPEHPLTGVVHAAGVLDDALVTSLTGEQLDRVLR
PKVDAAAHLHELTADLPLSWFVLYSSMMAAFGGPGQANYAAANAFLDGLAQHRRARGLPA
ASLGWGYWDQRSGMSEHLTDADLARMARSGVVPLSSAEGMELFDAALAAPEAHTLPVRLD
PATLRSRAADGALPPLLRTVAGTRRTAAPAGDRASEAAPAQRLAELPAAERDAALLDLVR
EQAAAVVANPDPRSIGAERAFKDAGFDSLTSVELRNRLNRLTGLNLPTTLLFDHPTPAAV
VRHVRGLLVGEDDAPVPAPVPASAAAGASGDTDDPVAVVAMSCRLPGGVRSPEDLWELLL
QGRDAIGGFPTDRGWPHDIYDPDPGRAGKSRVRAGGFVYDAPDFDAAFFGISPREAAAMD
PQQRLLLEVSWEAVERAGIAPSSLAGDPVGVYMGTNMQDYAADQRRVPEDAEGYLLTGRS
QSVVSGRIAYVLGVEGPAVTVDTACSSSLVSMHLAAQSLRQGECSLALAGGVTVMSRPLL
FVEFSRQRGLAPDGRCKTFSDAADGTGWSEGAGVLVLERLSDARRRGHPVLALLRSSAVN
QDGASNGLSAPNGPAQQRVIRQALAAAGLRPADVDAVESHGTGTVLGDPIEAQALSAAYG
DGRPPEHPLLVGAMKSNIGHTQAAAGVSGVIKMLTAMRHGALPRNLHCEQPSSHVDWSSG
ALRLLDRRLPWPDRDGGPRRAGVSAFGISGTNAHVLLEAPGADEAGDDHAEEAGGAAAPP
VLAWPVSARSGAALNAQAERLRSHAAAHPDESPRDVGHALATTRGAFEHRAVAVGRDRGE
LLASLEEIARGGGAARGVADDGATAFLFTGQGAQRPGMGRGLYESFPAFADAFDAVCAES
DRHIGCSLREIVFAEEGAAAAQALDRTEFAQPALFAVETALVRLLESWGVTPDAVLGHSI
GELVAAHVAGVWSLADACAMVAARGRLMQAMGSGGAMIAVDAAEDEVRAALAGSEDEVSL
AAVNGPRACVISGDPAAAERVAGRLGGRAKRLRVSHAFHSPHMEPMLAEFREVAAGLAYA
EPAVPLVSNVTGERAAAGELADPDYWVAQARRAVRFHDGLLALRRADTTRFLEVGPSGVL
TAAVRDGLADAPVTAACLLHRDGPEAVNAVSAVARMHTAGRRVDWAAFHGGGARRVDLPT
YAFQRERFWLDDASGSAPEAAHTPAEGEGAPGESEDPAEREFWRILEQEDLPGLRTLLGL
AADAPPETVLAALPSWHRRRRQRSAAASCTYRQAWRPHAVAATAPRGRWLLVHPEDADRP
VLDALAEALRAGGAEVVAAPLDAAACDRATAAACLPEDADRFDGVVSLLALDERPHRKAP
GVHAGLAATVCLVQALDDRGARARLWPVTRAAVAAGGTERSVRPEQAALWGLGRVLGLER
PDRLGGLVDLPPRVDDRAAEAAAAVVSGDGPEDQFAVRADGVSVPRVVRAPLEGGAGERP
AWRTGGTALVTGGTGGLAAHVARWLADRGAEHVVLASRRGAEPPVAGELRDRGVRVTCAA
CDAADRDALARLVEEVEAGGEPVRSVHHAAGVVRFAPLADTSPEDAAEVTAGKADGARNL
DELFADRDLDAFVLFSSVAGFWGSGGQGAYAAANAHLDGLALRRRARGLAATSVAWGPWA
GEGMNSQDGVEEHLVRRGLRPMAPETALAALEAVLGAAEPFAAVADVDWDRFALGYTADR
PRPLICEVVPADADTPAGTPADEAPGEGFAERMAALPSAERDRELLEVVRRQVAAVLGHA
SAEAVAPANAFHDAGFDSLMAVELRTRLREETGLPLSATTIFDYPDPQSLAGHLAGVLGA
QPDAEHGDGVHERLETSTADELFDFIDHELGFS
>A0A221W488|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinoalloteichus hoggarensis|TrEMBL
MTKAESEPIAIVGVSCRFPQAPDPVAFWRLLADGAEAIRPAPEDRFPAGTSAGFLDEVDR
FDAAFFGLSAHEAARMDPQQRLVLELSWEALESAGVLPATLAGGSTGVFVGAMAEDYRIV
AGREARDGYAPVGLYRSMIANRVSYFLRLRGPSLTVDTGQSSSLVSVHLACESLRAGEST
LALAGGVQLDLTPESTESLAALGVLSPDGRCHTLDHRANGIVRGEGGGVVVLKRLSDAVS
DGDVVHALILGSATNNDGGGASLTAPSGSAQEELLRTACARAGVDPAEVQYVELHGTGTR
VGDPVEAGALGAALGTSRPAETPLLVGSVKTNIGHLEGAAGIASLLKTVLAMRHGELPPS
LHFERSAPSVSLPGLGLRVQTERSDWPRGARRVAGVSSFGIGGTNCHVVLADSAPEVVPE
ISAAPVRPARGRQPRSAAEGTSAGHAPIVPGDQAPEQSVQGGSVPRSAGLVTPTWLLAAR
DPQALRAQAERLAAFATERTDLSAESIGAALRDTRTAFEHRAVLRGDTRAELLAATRALA
LGEPAANLVTGQADVGGRTVFVFPGQGAQWPGMAVELLDTVPVFAEHLEACAAALAPHID
WSLLDVLRGADGAADLTRIEVLQPTLFAMAVSLAQTWRAAGVEPDAVIGHSQGEVAAAYV
AGALSLTDAAKVAALRARVTADLLGDSGGGLLAVGVSEQEYGERFAAAAPRLSIAALNSP
TAIVLAGPGPALDDLAALAAAQGVRCRRVPAAEYASHSAAVEPAEQALRAAVADITPRRC
PVRFLSTATGDWVDGADLDADYWYRNLRNTVRFAPGIRALAASGHDVFVEASPHPLLVPA
IEETLAAEDSRPHVAVGTLRRDEPAVARILSGAAQLHVRGRSPDWTALLPPHAGEPVELP
TYAFRRRRHWLGGTVAERPAESRVPVRDAAELERLVVRLLEAVLGRSPVDAHRRFKDLNC
DSMALVELRNQVGTAVGRTIPVSALFSHPTPAALAAYLAAEDVAEAADSVDDDAVLHDVA
GAVGGPAADDPVAIVSMACRFPGEATSPEALWAAVAAGADLVSEWPLDRGWDVAGGYDPE
PGVPGRSYTRHGGFLDGASGFDADFFEVSPREASAMDPQQRLLLETSWEAVERAGLAPTS
LHGTDTGVFVGTMTQEYGARLHEADDDSGGYTLTGSAASVASGRIAYTLGLSGPSMTVDT
ACSSSLVALHLAVRALRQGECSMALVGGATVMATPGVFVEFSRQRGLAPDGRCKAFAEGA
DGTGWSEGVGVLVVERLSDARRLGHPVLAVVRGSAVNSDGASNGLTAPNGAAQERVIRRA
LADAGLAAHDVAAVEAHGTGTVLGDPIEAQALLATYGRDRPAGRPLWLGSLKSNIGHTQA
AAGVAGVIKMVEAMRHGVLPKTLHVDAPSSHVDWDSGAVRLLTEPVSWDGGDRPRRAGVS
SFGISGTNAHVILEEAPQLASSPEPKPSARHSETRQPTVESTDEAAVVPWLLSARSPAAL
AAQADRLAAFVSGEPEYDPADVGWSLATTRSVLDHRMVIVGAGRRELLAGLTEPVADVVR
AGAAGRVVLVFPGQGSQWVGMGRELLACSPVFAARFGECVDALGEWVDFAPLAALGDEVL
LSRVDVVQPLLFAVLVSLAAVWESFGVVPDAVVGHSQGEIAAAVVAGGLSLADGARVVCV
RSRLIAQTLAGHGGMYSVAEAVDAVRARVTGEFDGRVSVAAVNGPASVVVSGDPTALAEF
AARCEADGVRARRIPVDYASHSAQVERIEHDLPAALDGITPRGGSVRFFSTVTGDWLDTA
ELTPEYWYRSLRQTVRFHPAITALVDQGYTGFVESSPHPVLTMAIQETLDAVDADQPAWV
TGTLRRDDGGPRRLYDSLAQAWTRGHPVDWTPAFGDHARRVPLPTYPFQHSRYWLTSRPA
APREPTGTEWGYRVDWQPLTTGDAVRLAGTWLLVHLGADAGGAAAGLAEHGATVRTVSWD
GHGDLAESLRAAVDPDEPPAGVLLLFGAADGRPRPLAAGAAVTTRLLRALASAEIDAPLW
CVTRGAVAADDTDRLVDPDQAAVWGLGRVAALEHPRRWGGLIDLPVAGDGDGANPLAAAL
SRTDGEDQIAIRAAGTFGRRLVRAPLSAAAARPRGPHGTVLVTGGTGALGAHLARRLAEG
GAEHLVLVGRRGAEAAGVDELVAELTEAGTEVTVAACDVADRASVAALAERLTAAGTPVR
SLVHAAGIGPLEPLSELGEDSLDDVFAAKVGGLHNLDEAFDLAGMDDVLLFSSISAVWGV
ADHAAYAAANAYLDAFALRRAADGAPVRSIAWGPWGGGAGMIPAALADTLRRRGVPVLDP
AAAVRFLDRADDTADPVTIVAEVDWPRFLPVFTSARPAPLFSAFDGELDGGRDHTEPTRS
RDGGLRADLVGRSASERGRMLLDLVRRHTAAVLGRPGHDALDARRAFTELGFDSLTAVEL
RNRLTKATGLRLPTTLVYDHPSPSELARLLETELVADAAAAPATTAPRPTEPAHAVDAAE
PIAIVAMSCRLPGGLRSPEELWEFVAAGGDAIGGFPLDRGWDLGALFSRDQRARGRSYVR
EGGFLQDVAGFDAGFFGISPREALAMDPQQRLLLETAWEALERGGIDPRSLRGSRSGVFV
GLAEQYYGSVLRRDESADESYAVTGEAASIASGRIAYVLGAEGPALTVDTACSSSLVALH
LAVRALRAGECGLALAGAAMVMSTPSQFTGFSRQRGLAPDGRCKAFAEAADGFALAEGAG
MLVLQTLSAARRDGHPVLAVVRGSAVNSDGASNGLTAPNGPSQQRVIRAALADAGLAPSE
VDAVEAHGTGTRLGDPIEAQALLATYGRDRAEDRPLWLGSVKSNIGHTQTVAGLAGVIKM
VEAMRHGVLPTTMHVDAPTSRVDWDSGAVRLLTEPRDWPATGAPRRAGVSAFGISGTNAH
VLLEQAPEDFEPASDPQQAPDPVPSTSDPAAVVPWLLSARSPAALRAQAGLLAEHVEARP
DLSPVDLGHSLVRSRSAFECRAVVVGAERDELLAGLAAVDAAMTAGPAGRSALVFPGQGS
QWVGMGRELLACSPVFAARFGECVEALGEWVDFAPLAALGDEVLLSRVDVVQPLLFAVLV
SLASVWESFGVVPDAVVGHSQGEIAAAVVAGGLSLADGARVVCVRSRLIAQTLAGHGGMY
SVALPEDGIRDRLTGFASLSVAAVNGPSSVVVSGDPTELAEFAARCEADGVRARPIPVDY
ASHSVHVERIATDLPTALAGITPRSSEVGFFSTVTGDWLDTAELTPEYWYRNLRQTVRFH
SAITALTDHGYTGFVESSPHPVLTLPVQETLDAADLPDPDGILVTGTLRRDDGGLRRLYD
SLGQAWTRGYAVDWTPAFGDHPRRVPLPTYPFQRARYWPAVAAPADPVDSWRYRVAWPRV
DVAAPETGGTWLLVGPDPDDPLTQACADRLEHRGTTVVRLDAGGADRAGLAERLRTASAG
LDLRGVLSTLAVDDRPDPVEPALRRGLTGTLRLTQALLDTDLTAALWTVTRSAVAVAEEP
VAHPEQAAAWGLGVVASLDLPDRWGGLIDLPAEPTEADLDLLCAAVSGAGAEDQLAVRAD
GLHARRLVRAAGLAAAPWTPRGTIVITGGTGALGAHTARWLAAHGAEHLVLTSRRGADAP
GAAALADELTALGARVTLAACDVADRDAVAGLLDSLPGRPTAIVHAAGVVDTEVPLTELG
LGELADLFGAKVAGAEHLDALTRDLDLDAFVLFSSGAGVWGNTGQAGYAAANACLDALAH
RRHALGLPAASLSWGAWAGGGMVDEQVADRLRQRGVPAMAPELAVTAVAAAVGSGLPHLV
LADLDWARFAPAYTMARPRPLVGDLPEVRALADTDAGSDGGTRDGGDAVSGENDRTDFVT
TLAGLGPAERRRRLVDLVATAAADVLGHDGALTGPGRQTFRELGFDSVTAVDFRNRLGAV
VGRRLPATLVFDFPTPTALADQLLATVITPEERPDVRDPLAELDRFERGLTETPPTAAER
AALAGRLEALLHRWAAPAESEPATAADPLDAATDDEMFELIDRELGLA
>A0A0H2ZTV9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium avium (strain 104)|TrEMBL
MMVDQLQHATEALRKALVQVERLKRTNRALLERSSEPIAIVGMSCRFPGGVDSPEALWQM
VAEGRDVISEFPTDRGWDLAALYDPDPDARHKCYVNTGGFVDNVADFDPAFFGIAPSEAL
AMDPQHRMLLELSWEALERAGIDPSGLRGSATGVFAGLIVQGYGMLAEEIEGYRLTGMTS
SVASGRVSYVLGLEGPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGATVNATPTVF
VEFSRHRGLAPDGRCKAYAGAADGVGWSEGGAMLVVERLSDARRLGHPVLAVVRGSAVNQ
DGASNGLTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQ
DRGQPLWLGSIKSNMGHTQAAAGVAGVIKMVLAMRHELLPATLHVDEPSPHVDWSAGAVS
LLTEAQPWPGERPRRAGVSSFGISGTNAHVIIEAVPAVEPAHADAPALPVLPWVVSAKSA
AALRAQAARLAEYVRAQGELDIADVGWTLAGRATFEHRAVVVGGDRDRLLAGLDELAADD
PAASIIRGVATPAGKTVFVFPGQGSQWLGMATELLDTAPVFAQHIQACEEAFAEFVDWSL
IDALRGAPGAAGMDRVDVVQPALFAVMVSLAELWKSVGVSPDAVIGHSQGEIAAAYVAGA
LSLRDAARVVTLRSKLLRSLAGPGGMLSIACSTERARELLAPYGNRVSIAAVNGRSAVVV
SGEGAALDELAAFCADLALRTRRIDVDYASHSVEVEAIREDLAQALTGIEPRSSRIAFFS
TVTGNRLDTAGLDADYWYRNIRQTVQFDQTVRSAAEHGYRTFIESSPHPALVAGIEDTVN
DSLPGDTEAIVIPTLGRDDGGLERFLTSAATAFVAGVNVAWRGVLDGAGFVELPTYAFDR
RRFWLSGEGAAADASGLGLGTSEHPLLSAVVELPASGGVVLTGRLSPSLQGWLTDHAVSG
TVVFPGAGFVELAIRAGDEVGCSTVEELTLQAPLMLPAKDSGIGSVAVQVLVGEADESGR
RDVSIFSRPDSDSPWVCHAQGTLSTGSIEPGADLAAWPPAGATKVDIADGYQRLAARGYG
YGPAFQGLTAAWVRGDEVFAEVRLPDAAGGVTGFGVHPALLDAAMHALIVGHQIAGDTDE
VALPFAWQGVSLHAAGASAVRARLAPAQAPGTAASRAVSLELADGLGLPVLSVRAMVARS
VSERQLRAAVSAAGPDRLFEVAWAPVTVPAAHGEPPVHQVFESLAAEGDPVGESYRRTHE
ALAAVQSWLTEHDSGVLVVVTRGAMALAGEDVTDLSGAAVWGLVRSAQTEHPGRIVLIDS
DAALDDSALTAALATGEPQVLLRDGTVYTARVHGSRAVDGIMTPPEDRPWRLGISSAGTF
ENLQLEPVPNPDAALQPGQVRVALRAIATNFRDVMITLGMFTHDALLGGEGAGVVVEVGP
GVTEFSVGDSVYGFFPDGSGTLVPGDVRLLQHKPTHWSYPEAAGISAVFTTAYMAFIHLA
DVKPGQRVLVHAAAGGVGMAAVQLARHLGLEVFATASRGKWDTLRAMGFDDDHIGDSRTL
EFEDKFRSATGGAGMDVVLDSLAGEFVDASLRLVAPGGVFLEMGKTDIRDPGVVAREYPG
VRYRAFDLFEPGRPRMRQWMVELAGLFDAGVLNPLPVTTFDIRRGRAALRYLSQARHIGK
VVMTVPGALSAGTVLITGGTGMAGSTLARHLVTGHGVRDLALLSRTGPDAPGAAEFVAEL
EAAGARVQVIACDAADRAALAGVIAGISAERPLSGVIHAAGVLDDAMITSLTPERIDAVL
RAKVDAAWNLHELTRDMNLSAFVMFSSMAGLVGSSGQGNYAAANSFLDALAAHRRAHGLP
AISLAWGLWDQASAMTGGLDAADLARLGRDGILALSSDEAMELFDTALIVDEPFLAPARI
DLGALRAHAVAVPPMFADLVNAPTRRRVDDSLAAAKSKSALAHRLDGLPEAEQHAVLLEL
VRSHIATVLGSPTAEAIDPDKAFQELGFDSLTAVEMRNRLKTATGLALSPTLIFDYPTPN
ALAGYIRTELAGAPQETTHAPVVRATDDDPIAIVGMSCRFPGGVDSPEALWQMVAEGRDV
LSEFPTDRGWDLAGVYNPDPDVPGTCYTRTGGFVDNVADFDPAFFGIAPSEALAMDPQQR
MFLELSWEALERAGIDPVKLRGSATGMFAGVYTQGYGMGAAPIAEGFRLTGQSSSVASGR
VSYVLGLEGPAVSVDTACSSSLVALHMAVQSLRSGECDLALAGGVTVNATPDIFVEFSRM
RGLSVDGRCKAYAGAADGTGFSEGGGMLVVERLSDARRLGHPVLAVVRGSAVNQDGASNG
LTAPNGPSQQRVVRAALANAGLSAAEVDVVEGHGTGTTLGDPIEAQALLATYGQDRGQPL
WLGSIKSNMGHTQAAAGVAGVIKMVLAMRHELLPATLHVDEPSPHVDWSAGAVSLLTEAQ
PWPGERPRRAGVSSFGISGTNAHVIIEAVPAVEPAHADAPALPVLPWVVSAKSAAALRAQ
AARLAEYVRAQGELDIADVGWTLAGRATFEHRAVVVGGDRDRLLAGLDELAADDPAASII
RGVATPAGKTVFVFPGQGSQTLGMGRQLHAGYPVFAEAFDAVVAELDRHLLRPLRDVIWG
DDENVLNSTEFAQPALFAVEVALFRLLESWGVRPDFVMGHSIGELSAAHVAGVLSLQNAA
VLVAARGRFMQALPEGGAMIAVQATEAQVRPLLGPDVGIAAVNGPAAVVISGDHDAAVAI
AERLRAEGHRVHRLSVSHAFHSPLMEPMIDEFGTVAAGLAIDKPVIPIISNLTGQPAADD
FGSPEYWKCHVRDAVRFADSVRFAQSAGATRFLEVGPSSGLTAAIEETLADAPVVTVSAL
RKDRPEPVALVNAVAQGWVCGMDVDWRGALGTGHLVDLPTYAFDRRRFWLSGDGAASDAA
GLGLAAGDHALLGAVVELPASGGVLLTGRLSPASQGWLADHAVGGVVLFPGAGFVELAIR
AGDEVGCGIIDELNLAAPLVLPAGGSVAIQVVVDGPDDSGARAVSVFSRADAGAGWLLHA
EGVLRAGSAQPATDLSAWPPVGAVPVDLGDGYEQLAERGYRYGPAFRGLTSMWRRGDEIF
AEVNLPTDAGVSTTGFGVHPVMLDAALHAVMLASDGDDLPAGSMLVPFSWQRVSLHAAGA
AAVRARIVPVSPSAVSIELADGLGLPVLSVASMVARPVTDQQLLAAVSNSGPDRLFELIW
SAQPSTAVQPVSLLNWGATELDATDTDSDSGRFAVLFESAPVAGDVVTEVYAATRAVLPV
LQSWLARDGAGTLVVSTRGAMTLPGEDVTDLAGAAVWGLVRSAQTEHPGRIVLVDTDAPL
DADAVAAVLAVGEPQTLLRNGTVYTARVLGSRAVGALLVPPEDGPWRLGMSSYGTIENLR
LEPIPDADAPLGPGQVRVATSALAANFRDVMIALGLYPDPDAVMGIEASGVVIETASQDG
RVAVGDRVMGLFPDGTGTVATTDQRLLVKVPAGWSHTAAATASVVFATAYYALVDLADAR
PGQRVLVHAAAGGVGMAAVQLARHLGLEVFATASRGKWDTLRDMGFDDDHLGDSRGLDFE
DKFRAVTGGAGMDIVLDSLSGDSVDASLRLVAPGGIFLEMGKTDIRDPEVVAAEHPGVRY
RAFDLFEAGPDRIARLLDELAAMFGEDVLRPLPVTRFDVRRAPAALRYLSQARHVGKVVM
TMPDAWTAGTVLITGATGMAGSAVARHVVTRHGARNLVLVSRRGLDAPDAAELVAELTAA
GAHAEVVACDAADREALAKVIADIPMQHPLTGVIHAAGVLDDAVVTSLTPQRIDTVLRAK
VDAAWNLHELTRDLDVGAFVMFSSIAGLAGASGQGNYAAGNSFLDGLAAHRRAHGLPAIS
LGWGLWDQASAMTGGLGAADLARFGRDGIVAMSSQEALELMDTALIVDEPFLLPAHIDLA
ALRVKFDGGTLPPMFVDLINAPTRRQVDDSLAAAKSKSALLQRLEGLPEDEQQAVLLDLV
RSNIATVLGSSSPEAIHPDRAFQELGFDSLTAVEMRNRLKAATGLALSPTLIFDYPNSAA
LAGYMYRELVGTSEQPTAAAAPGEAEIQRVVGSIPVKRLRQAGVLELLLALANESTGTAQ
SATPAVTTEKDIADMDLDDLVNAALLDDDDE
>A0A100J2R2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MPLTYGYERFGGPEVERFAEVPRPVPGAGDLLIAVRAAGVNPVDHKRRSGRLPAGAPAVA
LPAVMGGEAAGEVVAVGAGVAGFAVGDAVLGGPTTGGFAQYALLPARAAVRKPAEVSWTD
AACLPIAGATGYAAVRRLGLPAGATLLIAGVAGGVGVVAAQVAVGLGVNVVGVAGPDKRA
FVEGLGVRFVASGTGLAAAVPGGVDGVLDLVGGEVLRESAGLVADRKRLASGADREAVAA
LGGSALGPVRAPAILEAVVELVRTGTLDPKVTSIVPFARAATAVRAVESGHGRGKTVLEM
SGAPLDPS
>R4YYQ4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Candidatus Microthrix parvicella RN1|TrEMBL
MGAPHITKTHDVLADVGCMSLPGTDPVPALRAAQRCGATPILWATGQPIANQLDPLVVWA
DVPPDGPLPPNVTALIAATERAAAIDPERTDLVRIPAINSIGQLDKALSLLAQSSGPGHL
VLVGNEAAGPVGDTSTFILLQQVTRALRRGEHQAPAIWVRGGIGPNTAAAAIAGGASGVI
LDTQTALLRESTVPPTVRRIIEAADGSETRVLSGHRVFVRPDLPTADRESLPDALNFGFN
DPQTQVIPAGQDLPVARRLATIGVTVAGAVQAIRRAMYADVSAASTTATLRPGGPLAERT
GATHPVLQGPMTRVSDTPAFTEAVARGGGLPFLALALLRGPEVERLLTETTDRLGELPWG
VGILGFVPPELRAEQLEVVKAYRPPMAIIAGGRPSQAKELDDLGIRTYLHVPSPGLLQRF
LADGARRFIFEGRECGGHVGPRSSFALWQAQLDVLADHANVAELDVIFAGGIHDDTSAAM
VAAMAQPLAARGAAIGVLAGTAYLFTEEIVTSGAIVPGFQRAALECTATSLVETAPGHAT
RCVAGPFVEAFEARRGELVAADVPASERWAELEQMNLGRLRLASKGLERTAAGLTEVDEA
GQREGGMFMIGEVATMGHEPLTVAALHDRLTTGSVGLLAHRTEELTEAGFLPADDEGRAP
APLDIAIIGMECVLPGAANVEEFWTNTVLGRNAVTEVPHSRWDADRFFDPSGDAANSGLL
SPSKWGAFVPPVPFDPLAFGIPPASLAAIEPVQLLSLEVASRALANAGYEHRHFDRDRTS
VIFGAEAGTDLSSSYGFRSIWPSLLGELPPELDDHLPRLTEDSFPGLLTNVISGRIANRL
DLGGANYTVDAACASSLTALDAACKELTAGSSDMVLCGGADLHNGINDYLLFSSVHALSP
TGQCRTFSSDADGITLGEGIACVVLKRLEDARRDGDTIHAVIKAVAASSDGRHLGLTAPR
KDGQVRCLERAYAQSGIDPADVGLMEAHGTGTVVGDRTELATLTELFGGAGAEVGSTVLG
SVKSQIGHTKCAAGLAGLIRVARAVSTGVRPPTNNITTPNDYWDPTTSPFRLDGSATPWL
DEHRTAGVSGFGFGGTNFHAVIEAPDGEPTPAHGLTAWPAELFVFTGATLTAAKVMVDQL
VGHLDHYGPAAEPLRNLAATVWARRSGPPQVSVIATDAADLRAKLTTVLATADTATETTG
STASTGSTAPTGGSDRPSLPRIHWANPMAEDAKVAFVYPGQGSQRPRMLSDLYVAFPHLR
EVFREGARWTDLLFPPTAFDSETRAAQLAAVTDTRVAQPTLGIAGITLTRLLDTLGVRPD
LAAGHSYGELVALWAAGALPTDGFLDLSEARGEAILAATMMGGEPPAEGETNGASETNEP
MDDAGAMAALALGADRAEEIIDSLTLSRAAVGDACVVVANRNAPNQSVVSGPTAAVRAVV
DEATRLGERATLLNVACAFHSPMVAAAATTLGARLNEIDLAEPLFDVYSNVTARPYGDAD
DVARLLAAQVAEPVRFTDEIEAMYAAGTRVFVEAGPGRVLSRLVGLTLGDRPHQAINCDV
AGESSLNNLLDALGRLAMTGLPVTLDALFDKRTITVDLSARGAVPGWSVDGHLVRGRDGS
PVSGGLRPAHEFVEAHPMGLPNDNHPNGRPRGEAGLTDGFGADPALMQYLQGMREMVAAQ
RDVMMSYLGVAVAPGSPVIDTTLTAGSTSPSLATRHRSPEANSSNDQGVEHGRHQGEPAG
DDAAPPVLGAAELEALVTSIVADRTGYPVDMLNPDLDLEADLSIDSIKRIEILGELAERA
GLPGADEGSLDESVVEALAMIKTIRGIATWIVEHRDDPAEGNTEASGVPTDPTDERPGGT
DVAGLGDDDQSITVPDEALSLLPVVVAASPDGEPVTVRDLTVWITDGVAATDLAAAVAAG
GGTPVLFDGDAAVPDGDPDVLIDTTGLSNTPGLSNTVRSTDLTASGANRSYATLRQALLR
GVRHVVLATGDGGRFGMDHHRSAEPGQSLPGPTGDASPPEGAGALRVGGYRGLARAAARE
YPEVGMRCVDLDPTETPSALAAHLMAEIGGPDPDNCVMGRTADSRVAIRWQRVRPDAPTD
ADASGEGRPDLGPGRAALLTGGARGITAKVAVGLAGRFGCPIALVGRSPEPIGTPSAELA
DHPDDRELRRRLIEGGMTNPRDIESRLASLSAEAEIRATMASLTDLGVPVRYLQADVADP
ETVEAAMATVAAELAPIGLVVHGAGVLADHLIRDKGPEEFQRVWHTKVTGALALHRAAPE
DADLVFFASISGAVGNVGQVDYGAANDALDLLAHTLEDRNVLAIDWGPWAGGGMVSPELE
REYERRGVGLVPVEAGVNLVCRHVAAGLPQRQVMFVRAKPAAIGAVEAEPVGASGDGGA
>A0A060Q3L3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia brasiliensis|TrEMBL
MSSHRLPDGSIPVLLSSDAPDSLRREAAAILSYLEAHAAVGPDQVADMLFRTRVARRYRA
LAMVTERAELVEALRAVAAGEPHAAVIATGSAAKARKIGYIFPGQGSQYAGMGRMFYENS
PAYRAAVDEAEAVFQDLFELSPRSYLLAESEPGHNLLRIVQPALFMQMVGLAAMWRAAGV
VPAVTVGHSQGELAAGVVSGVITLADAVRVVTLRGGLVDTIAKQEDREDKYSMAVVGVDR
EECEAILARHSGWAELSVINSPHVLAIGGERRTVAQVVADLTAEGKFAKEIRVGYPAHTS
VVTEFRDSFLDNSLAAKLDRPEFTATEIECIGSTLGTAITPDLPVGDYWYWNLRNRVRFD
LAIALAAERGVDTYLEIADHPALFLAVQENLSAVAQQRDFQTIGTSRRTATDLREFTRNL
GLVAVSDLGYDWSALRTDSAGAPRLPLLDFPNTQMNPKHLWAAYDHTAARTAVPNAVANA
PISVVAEQRTVPAQRIVEQWVRLRSRALVPPRTIAVLDHGGRSTELVAALGDAAALHGVT
IVDPAAATHSAGTAFDTAVVVLPELDDLTTDAAVAELAEFLGDRTWLPRLDGVRDIWLVT
VGGEHVLEADVPNLFHAAAQAGFRCLAADHLGVSFRHVDLAPGRPLPDTAKALMVALHTA
REPELALRDGGVYAKRLVAEDVSAVSPLGADDLREVVIVGGTGKLGLDFCERFARDGAGR
ITLLSRSGGAAEALARIEQIRQLGATEVVVRRCDVTDEASVRALADEYGSTPADLIVHAA
VDYVAAAELTPVSVREAAAPKVVALEHLVQHFPRTSNGRVVLCSSLSATIGGRGHMAYAA
VNRMLDAAAARYRSQGIASTSVQWGLWRAVGADQADALAAISGTGLRPMEPASAIAAGIT
ARAENVIIATADWDRLATLFSAFGFDPLFSTLDLGDLPAEQAELPADPVPAPAPVPPEPP
AAAVQVAAPNTAEQVRFALRAVMGMDTTETIDGSVPLVALGLDSLQALDLRKRIEVELQR
ELPVTAILGGASLDEVVTLLG
>A0A1X0L5J4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium persicum|TrEMBL
MTSRGYRLPDGAIPVLVTSDNPDLVSREAAAVLTYVADHPEVAPQAIADMLFRTRIARKH
RALAMAADRDELVNALRAIVDGRDHPSVVCTQTAAAARRVAYVFPGQGGQRPGMGRLFYQ
AMPAFRAEVDRCAAAFQAQLGTSPLNYLLDEGLSVDNSAITVQPALFTQMAGLAAMWRSV
GVAPDVTIGHSQGEIAAAYVSGAITLADAVSIIGIRARAADGFAAGDYAMAVIAADRDAC
EDLLARCSGWAQLSVINSPNLAGISGDRETVQMIVDTFSRRDMFARVIEVRFPAHTSVIS
ALGDEFCAATRRELRNPKFLDTDIDCLGATLGGPITQDLPLDQYWFWNLRNTVRFDKAIA
AAVARGVDTFVELAVHPSLQLAIEENLAAASDDGNDRDPMVVGTSIREATDLGEFTRNLG
RVAVHDLAYAWDQLSAEPHGPVALPLPDFPNTVLNETKLWLPYQDTLPQRPRRTTTTSGP
VRNPIGQIAPPRLLAENWVRLSQRSLVAPRAIGIVDHSGGCAEQAAALCIAAADLGATAR
VVDGRNSSATTGLDTLVILLPRSAKLDFAAAAAAVAAFFSDRTWWPGISAAITDCWLVTI
GGEAVVADDPSPDPVHAAAISGFRSIGCEHPRVCFRHLDLAAGSPLPDASAAVLAALHTA
RESALALRDGVLYAKRIVESEAPVADSNLATPQHVLIVGGTGNLGLDFCEHLARRGARRI
TLVSRSGETAAVANRLQQIRSATSAHIEAAACDVGDPAAVLRLATAAQDTPADLIVHAAV
QYSGMELADITVEKAEKALRAKVVGMSMVLETIPRTADCRILLCSSVAATVGGRGLIVYA
ASNRMLDAMAHRLRSEGLDCVSVQWGQWHVASAAADSGMAKLAFTGLLPMSASDALALGM
GRLRGNAIVAAFDAERATSVLQACGHGGLLSQLTSHVTVGNSTRDDTATGAIHRLLKLLA
GAIGVDDVEEIDTTVPMVALGLDSLQALELRRRVKAEFDHELEVSDLLGGASIDDILATL
R
>A0A0U0QT96|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MGAVAYRELPTYRTATDTCAAAFAAAGVDSPLPYLIAPPGTDERQAFCEIEIEGAQFVHA
VALAEVWRSCGVLPDLTVGHSLGEVAAAYLAGSITLSDAVAVVAARANVVGRLPGRYAVA
ALGIGEQDASALIATTGGWLELSVVNASSTVAVSGERQAVAAIVDTVRSSGHFARGITVG
FPVHTSVLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVAPGTTFGDYWYANLRHTVRF
DRAVESAIRCGARAFIEISAHPALLFAIGQNCEGAANLPDGPAVLVGSARRGERFVDALS
ANIVSAAVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVPMWAHPEPLPPVSGLTIAVE
RWERMVPSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHPDTELSAARDAELILVIAPD
FEHTDAVRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVGAEQVDAADAVPSAGQAALA
AMHRSIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGFGETALRGSVNGYTLFERTL
ADAPAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGARRIVLLSRRAADQATVAML
RKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAGSVISGTAPGVTSAAVVDNF
AAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYSAANRLLDVMAAQLRAQGRH
CVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQMAPQQAIEASLHEFTVDPLVFAA
DAARLQMLLDSRQFERYEGPTDPNLTIVDAVRTQLAAVLGIPQAGEVNLQESLFDLGVDS
MLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLEDADERSHTAQKVDISRD
>B6VMU4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Photorhabdus asymbiotica subsp. asymbiotica (strain ATCC 43949 / 3105-77)|TrEMBL
MLCMRLFHLQREEYMSETYSISMYGKKGQGDIAIIGMASHFPDASNLHEFWENIIAKRDS
LTDITTVSEIEYWSKEDFYHPDASVADKTYSHKAGFVPAIDFDPVEFKIPPTIIDSISTI
QLFSLYVAKQAMLDAGLIGQENKCVNRDRIGVILGGSGNGNTLFSLSARQQTPYLRKIMI
KSGLPEEVVDEVIDRVHDSCLEWNEDSLPGFLGNVACGRIASHFDLGGTTYMVDAACASS
LAAIKAAIGELNSGSCDVVLTGGVNLENSAFSFICFSKTPALSKSNLSRPFDRDSDGIML
GDGVGMLVLKRLKDAELDGDKIYAVIKSIEASSDGKAKSIFAPRYEGQVKALKRAYASAG
LTPADIQLIEAHGTGTATGDNTELKSLRMVFDEYNIAAKSVAIGSIKSQIGHTRSAAGAA
SMIKTTLALYHKVLPPTINVSQPDEMLSGDNGPFYINNEPRPWLRPLNGAPRRAALSAFG
FGGTNFHAILEEYEPEQSGAYRLNGQAVTLLFCGETPQQLLVRCEAALARFGSASSAGQV
LREHLVHQDLNGLQPHQARLLFVATSATQAAELMAVAVEQLKQKSASGWEHPLGIYYQPS
AKNLDGKVVALFPGQGSQYVNMGRDIANDYPEMRQALEALDAIAVNERGQRVSHVIYPTP
VFSDAERQQQNAILTDTANAQPALGAISAGYFAILKESGFNPDFVAGHSYGEVTALWAAG
VLSDADFYRVSLARGMAAASAVDDRGADVGAMLAASLTLEQRENILELYPEITVANDNSA
SQVVLAGATTLIHQLHNELKARQIHCRLLPVSAAFHTEFIQSAYAPFREYLEQISFRSPQ
CALFSSATAAPYSQSPADIASLLAEQLVMPVRFRETIETIYQRGGRLFVEIGPKGVLSKL
VADILNGREHSIISVNTSDKGEERLQLARAQARLLAEGVRLNVLDRHARVQLPSEEKTNH
LTFRLSGGFFMSDKNQARRERAMRDGDTAMVERFMANRAPVVAAPVISKPPPAPVIQTGS
PKGPTPLLQRSTSVAIQKRDNPMEQNNQLNENMGDSNLEGLLQAQRVMSQLHEQFQTNQK
EYIQLLGSLLNKQYTLLEKFQDHQNLPTMLSSLGQSVQLLEKNLELYHSNHERYFATQQS
LFQSGQAVQSVAAVVTPKVTPVVAPAPIMKEIVEPRPAMFVTPSAPVMNQPVTLAKPSIG
DPELELKIKRLEQITEANIIGKLVAIISDKTGYPQDMIDAEMDLEADLGIDSIKRLEIFG
AMFDTFSADSGIYHDVLKNKYLEAFDIEVLSNIRKISMFFKQMNDEIIADIRRKNSGDVP
IEEAAASKDSLIGDNAREQGNGQTQHSLQALEGGRAEAPLRTLGFVTSTSSVPKADSAKK
SWLNRN
>A0A853SAW2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Janthinobacterium lividum|TrEMBL
MEQANTDLLAKQHDIIRQSRQQIEALSARLDQPIAIIGMDCRVPGADSPQALWQLLAEGR
ETVSEVPRERWDIEDYYAQEPGTPGKTYARRAGYLRDLDLFDTKFFGISPREAQQMDPQQ
RLLLEVSYQALEHARLPPSTLRDQAVGVFVGISSSEYAVLTFGKERQSSQDAYSVTGTST
NSAAGRLAYFYGFNGPALAIDTACSSSLVAIYQACRSLVNDECHTALAGGVNCLLLPEPN
IALAQNKVLSASGHCSPFSAKADGMVRSEGCGVLVLKRLSDALAENCPVLAVIRGGHVNQ
DGASSGLTVPNGYAQQSLIMQALKKAKLEPAAIRYVEAHGTGTALGDPIEARALQQALCA
GQERSEPLLIGSLKAHIGHLEAASGIASVIKVVLALQHRLLPAQINLDERTPHVDWNAGL
DVVREAVPLVFGPDTPFYAGVSSFGFSGTNAHLILQDACSAVPGDGSTHPAATAPLTHFL
GISAKDPVALKTLLASNRDFFAGERAWGEACEALNAGRTHYPWRAGFVAKDREALIEQLE
AACRGEPATPVSHAPALAWLFTGQGSQYVQMGRALFDTEPAFRALLESCDRELSAHLGRS
ILPVIWGEVAGVNATEYTQPAIFCLQYALSHFLLSLGVQPRFVLGHSIGEYAAAVVAGVF
GLRDAARMIVYRGRLMAQRCTAGGMLALLADRERADALVREGGAGVVIAVINGPNNHVLS
GEPAVIERLARLAQEQGLRCVPLPVSHAFHSPLMDPMLDEFEQVVRQTEFSRPRIGFISS
ALGRVADSELTDPAYWVKHVRDPVLFEQAMAALAVEDDWTAALTRLCLEIGPHEQIIGMA
RMLPIATMAQWRNLLQRNDDLTSFAEALRSMYMSGMPLHWPRKPPQGDPLLPLPSYPFAR
QRYWLPDVSGAAIIPSAQDYAVEWIAAPLSGSVVPVRGHWLLLVEDEAFARSLSRQLTQA
GASVVTLSFAAAKLPVDLDLAGFDAVIHSVNERAQAPAAAAVHALIRLAGLVSPTPGAPG
PRLICVVDNGAAGYLPMGSSLASACRCLREEETGLTLTLAGLDADLGSGARAQVLLSELG
IDRGADWERRVVDGHALVPRLAEVRPAKQQAAVPLRADRSYLITGGTGALGLVFADALIG
LGARDVVLASRSCSDAGLAPLRASAEAAGARLTVYKVDLCAPDTVHALFERLSQAHAPLA
GIIHAAGQLADAGFRQMDAQAFDRAFGAKAGGAWLLDHLSRDLALDFFLMTSSIAAVLGA
PGQTNYAAANGYLDALAQQRRAAGRPAVSLRLGAMAGAGMAGGEIAARQLLRAGVVPVDP
VQLRIRSAQWFAQLEPLAMVASFDWSTIHARQGRLVRPLLEAFVPGAAAASPLLPPVAVT
PAADVRRDLDAVGTLLRETIASTLAMPDPQAIGDDETLNALGMDSVTLVELRGKLARQLG
CELPTHLLFDFPQVGKLARHLHALLNEDSTSASMPLRSVAAASEQDIAIVGIGCRFPGGV
NSPEAFWSALLEGRDLVGQVDALRWDASQLVREGALVTARAGIIDDVDAFDCEFFGITPR
EAQCMDPQQRLLLELGWEALERSGYDFAAQDVVGGIFVGPGPNDYARRFDTEAQALSHHH
STGNALSVTAGRLAFMLDWQGPALAVDTACSSSLMAVHLAVQSLRTGECDIALAGGVNLL
LSPETSVLLSKGNMLASDGRCKTFDARADGYVRSEGCGMVVLKRLGDALADGDQVLAVVR
GTAANHDGHSQGLTAPNGQAQQRVLRQALADASVDPAQVELLEAHGTGTPLGDPIEMAAA
QAVYVDGVARQAPLWISSVKTNIGHAEAAAGIAGLIKAVLCLQHGTIVPHLHFTQINPEV
KLDPALVHIPTNVQAWPGNGIKYASVSSFGFSGTNVHVVLQSAPVPTQPASRGLPPAGLR
ISAASHMALVELMRVFRDVLADLPPEHYAEFRAQAWRRVELRHTQVIEAATPAVAVESLN
RLLLELGAASGGARDAYPSSVGRVPTYPFERQRFWLNPPANKRRAAPLGLRLGARDAHQV
VYALDYAQQPPFRLEDHLVHGKPVVPAAAHLALIVGMLDDLRGKQAWQLVDVLCEEPLVV
DDDNGVVRYQFSRLPEGDAGYSVEVLSDASGRTRRHLRAHAHAATVAPKTVQGPASGSAV
ARIDGEAFYDRLYSPEIRLAHTFRSITSIEQYVGHSVAEVAWTTPLNGLLVPGELDSLLQ
TIALATLADQPERSHMGGATIPLAIDRLTVRPRVRPEVSAREPVVCVTRLVNEDDDGGSF
VHDLAVAEPGHLPFLSIEGLVTRRISEQQIGQTKAGSSYLVEEWVARPLQDDRSISSEPI
LVFLNSAQDAIGQRWHSFGAADGGLDASTCDDAAVLQAVGERAACLLFRLPPVADLGGAT
PCWADHAFSLVMAARRVSRLSKALSSAGKAIGFCVISEHHPLVAGEGAGSPLYGFAQGLC
KSLSLEWPERVVSMLDADGATLEHHAPALLAELSAAGGDWVAYRGGHRHVLRIAELPLPS
PIPLPSFRCHDDGIYLVTGGLGDLAVETCRWLSGKGARHLLLVGRRTADARIAQQLAELH
VITGARIDYRPCDVADGEALAGLFAEVGRSGAVRGIFHCAGVLADGTFEFLDNDDFGQVM
QAKLLGSWHLHRLSLELELDCFVMYSSLASLFGAAGQSNYAAANGFMDQLAQFRRRQGLP
ALSINWSGWDGIGMASKQETRGSKNGLRRLAPAQAIVDLERAMATERAQLGVVDVDWPVF
ANQWHGKPPALVEDWLALRLPAKGEQSVTVASVVVRALQELPLLARPEAVRQRVRAIARH
IMALDDSRPFADDKPFQELGFDSLMSIELKSKLQENFGIRVPATVVFDYPNVESLVAYIM
RVIDLDETRPAPQPAAMEQQADALDDLDEDQLSEILEKLL
>D2BW70|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Dickeya zeae (strain Ech586)|TrEMBL
MGMDIAIIGISCRFPDANNYSDFWENIIHQRNSVSEIADVNRDTQPDNRRSLHWPDASEK
RWAAFVNNVEGFDNQFFGVIPKVAETMDPQQRIMLELTWSCLEDAGIAPSTLRGHKVGVI
LGVFNNDYKELQENTHAPIEAHHSTGTATSIIANRISHFFGFRGPSVAIDTACSGSLNAI
HNAIQAIVSGDCDIAISGGVNLILTSTRHQSFAKMGMMSPTGACHSFDSRADGYVRGEGA
GVLLLKPLDKALADGDVIHGVIKGSAVNHCGTTYTLTYPSAEAQADVIVDAHTNAGVPVD
SIGLVEAHGTGTPKGDPIEFSGLTHAFSTLAQQQGATLNEAYCGVTSVKSNIGHLEAAAG
VAGIIKVLLAFKHRTLPPLRHFQSLNPKIDTTATPFFFVDKAREWPRLAQDTPRRAGVSS
FGFGGTNAHIVLEEAPEPVNAAHQENQPATGTPYLIVLSAKSPAALLQRQKDLIDWLREH
ADASLSAVSATLLLRRDHLAYRYSCVGSDRQAIIQALTQAVEQGPVSLQEHVADDAQALE
NARIEGESLLDALREADMTTATHLLQQLGACYVRGVQLDWSRLFDGVNPPHVALPGYPFI
HTAFWLSDSYRADSSSCALRGARHRVVNVGSSRYQARLAGDEFFIAGHQIGGQTILPGVV
YLELVRAAFTDAIALNDADALSFSQVAWLKPLEFHHAATDLFIQLDPHQPGKQWLFQVID
NDQALYCQGMVGFSDAEHPALPAVALTDDAAVRDAPASYQLLDSLQMCYGAPLRAIQQIR
FNEYACIAQLTLPDAPLSDAHSNDFVIHPSLADGALQSAVVWATEKLRASRQDNQQGALV
IPFALEALVLLRPCHSAMTATITVSDEHLLHDGVFKVDIHVCEANHPERVALVFRGLSLR
VLDDSLTAADRSTSEQRLPALSDGINLYQPYWIEKPVSEADEPMTQLVLVGEEQDVDRLA
SLLAQSENPPQMQRILLASALDVNREVASGWVRPGHHDDFIAAVDALLSQGATFERVLWV
NAPQASADFATRLNQGPHSLFALTKAMMRKVKKARFVHFHLADENLPDVAAISGFYRTLR
VEKPAYIGRVVQYEAVADGELDASTAIAALIKTEFSDVSKDADVRYRQGVRLVRRFVVDT
PSSASAHPSSRAIAAVDTASVADAVNRPVSAPTVLRQQGTYLITGGLGALGLIFARFLCS
RYGATVYLSGRSALDEQRQQQLDDLNTLGGNAIYQACDMNDPASVQALIGAIRTAGHELN
GVIHSAGVIEDNFILRKSPEAFERVITPKAIGTWLLDDATRELPLDFFVLFSSVTGVLGN
MGQCDYAFGNAFEDYFAFQRNVRQQQGERSGKTLSLNWPYWQDGGMRLTEKEAGFLKSQF
GIVPLLTEDGIAIFDYALQSQASQLVVMPGVPGERARIDEVLGVVEPTTASSQQPDAAAL
ASTDVTDPHALQDVVIRYLSELFARKLQIPPHFERHGFFRDYGFDSVVVIDLVNELKKTF
GSALPMTLFFEYQTMDELSRFLLENCQDACRGLQGNAPSAAVVPPALHAAASTSTSVRAV
APAPRAAQPTLNDDDIAIIGIAGRYPEAQNLEQFWANLSQGRDCVIEIPADRWDDRWFQQ
GAATPGKSYSRWGGFLSDVERFDLRYFNISPKETEIMDPNEWLFLESVTHAIEDAGYTAD
KLAPAHAGRENRVGVYVGMMWGDYQLHAVTSPEQEWTTSHSSYWSVANRVSHFFNFSGPS
MALDTACSSSLTAIHIACQALRSGDIPVAIAGGVNLSLHPYKYHLLSNMHFLSSDGRCRS
FGEGGTGYVPGEGVGAVVLKPLSRAQAEGDHIYGIIRGTAVNHGGKTSGFTVPNAKRQAE
LIAEALETARVNPRHISYVEAHGTGTKLGDPIEISGLNKAFSIAGDSSKYCAIGSVKANI
GHLEAAAGMSALTKVLLQMKHQTLVPSIQSDVINPFIDFQSGPFRVQQSLEHWQRPVLEV
IQQDGQSVTREIPRIAGISSFGAGGSNAHLIVEEYIAPPSASVDADKGKPALIVLSARRE
PALQAMAGQLADFIAQHPALSLQDMAYTLQVGRVAHEYRLAFVAETATEAVNLLRAYTQQ
QLSGLSTGHRDNLRQATSTPPLAEWLKQGRLGALGEAWANGHEVDWSQLHVATRRQRLSL
PGYAFQRQDCWAPALPATAPLTNAASGVGVLHPLIDANISTLAVQAFRKRLRAEEFFLSD
HRLGDNRILPGAAYIEMSLSASELALQGRALPASGERPLLSQVQNIQWRQPILVASDDME
VEIALTPSQGGLDFDIYRADGDQRHVYGSGRLCEDASPQPEPANLHRLQANGQVYQRNDI
DAAFRQRGFTLGPTFQVIECLYANAEEALAELKFPDGLSAASVVQPFILPPSLLDGALRT
ALGIGGFSATANTLEVPVALAKLQIFKPIDGICYAYARRDNAVGGATASYHIDLLDSIGN
VVVRLTQLQTQAVPHLGMKSSRAVKVTSSAPMGADVTRAPQPVAMASAMPVASQQSAGAV
SAHDALVSTLIAQVVDVTKLDIGEVTASGPLSNYGLDSMMILALNEKLAAAFEGLPQTLF
YEYEDLASLADYLLENYPDQVTAFTGVVAAAPQAVAQSASIDATIPVAPTIASATAPTRP
VRDSVLEYLIANIVEVTKLDASEVRPATQLSDYGLDSMMILALNGKLAATFGEVSQTLFY
EYPDIDSLADFLCESYPEQVAALQPTTAVAPAPVALTLPEESRVSAATGDTEGDDDASSR
GLFDSLTAAIGPTAANLSVLTPLWQWPLDTVNLIRLQHELDARFTEAHASDVYRYQSLAE
WAETVQVAPQPASAPARTNEVSAAPARPTLASLLNHSRIDALKRHTSGEAGASSDIAVVG
LSGRYPGARNVDEFWANLTGGVDSVTEIPLSRWDYHPHFSPERGPKNKVYSKWGGFIDDV
DKFDSQYFNISPREAELLDPQERLFLQTAWECISDASYSRQALSKAQVGVYVGVMWSHYQ
CIETTEKQHESGWAMSLHSSVANRVSFYFNLNGPSVALDTMCSSSLTALHMACQAIQNGD
CNMAIAGGINLIVHPMKYYQLGQNQFLSSDGRCRAFGEGGDGYVPGEGMGAVLLKPLQQA
IADGDQIYGVIKATALNHGGKTSGFTVPNQAAQSNVISTALSRAGWDPASVDYIEAHGTG
TMLGDPIEISGLTKAFSRISAQHYRDQHHAQQGATPALLPGQCRIGSVKSNIGHLESAAG
IAGLTKILLQLRHRQIVPSLHSRTLNEKINFAASPFRVVQSLEPWDAALDHPRRAGLSAF
GAGGSNAHVLIEEAPTRAPAHLLPGEPRLFVLSADSDARLALYVERMVHFLRQAVREPHT
APDFDSLAFSSLVGRDAMTERLAVVASSLDDLLNQLEQYQREGAAKQLFRGHIAGGGERL
DTILEGKQLDELITSLVQERQLLRLGRLWTTMLDVNWQQFAPSLFTTKGMTTSGSTTSTT
AGTVRRVSFPPLPLMLRSHWLALPSAQDALHRATSLHPLIDQNISTLAQQKFTKQLTGQE
RYLRDHVVGSRDARMILPGSAYIEMLHAAGQLAMESDWTVAAIRNLMWMNALEVDSEPVD
VEIALAHTGDDNVQVAVRNRHTDVLSLEAELVYRPEAEQPEEEWIDLEALRSSGKCESDQ
AAIYADFARMGFAYGPSYQVTRERYRFADAALSHLCLPEGVHADAFYLHPSLLDGALRTC
LAVGLEPVEYATPIVPFSLGELEFRHPLGTECYAYVTPAQSQAGSTIQKHDITLVDATGR
VLARLRDFAARRLEQDISAAPPSASQDVQYYAYEWQASPLPAVVSDASTRTATTRVLVLS
DNESLAEALRARYGDDTSIITATAASAFAQHDSHRFSVDTQSASSMRALCEQLAEQQWWP
THIVQAIGTDNHFDDVTAIGNASPLHAPLQALRHLFVALETVNPGQALRCVNVYTASDDQ
VEPQQDAVSGYARSLLTINHRFELFTLRSDANDAASLADAVYQEFVQRPQALAGLEVAYR
QGVRYQRQAGAITPPPADGQGSQPQLRFVQHGHYVITGGAGKLGLLMAQYLASRYQARLV
LSGRSAQPSEAVMQQLAAMRELGAEVCYVAADVAQDGQADALIAQAKAAFGALDGVLHCA
GVASATPMTMLSDDEFDALIGPKVDGLVALDRATAQEPLAVFINFSSVSAVLGDLGSGAY
AAGNRFMDSHALWRTQQVKKGQRSGQTLSVNWPLWASGQMNIEQDDASLFEFSGMAALGQ
EAGIIALERALLEQRPELLVAVGDRNKVARSLRIQVEETVQPAPSVAVPTLTQAPRPQPT
AVIATPAGDSAYARSESALKEMISAITKLPASDIAVDATFEQLGMDSVMLMELRAVLEKE
YDGLPKTAPFEYNTTAKLAGYLCERYGATPVVHTPEAAPQRTDTVSHHHASAPVAPPVKR
TVPAAATDALRSRAMRTPMRSSLSSTASIQADSDAVAIIGMAGEFPGAASLADFWADIQA
GKESLSAIPDARWTLPAEDNGNPRYVNRGGFLSNVDVFDPAMFRMSGEEASRLDPQVRVL
LRSAWHALENAGYTPAALNDQQVGVYVGAMNEDFTWVMAEIYARTGRYPGAGSVVSELAN
RISFLMNLRGPSFSIATTCASSLTSVHIARKAILGGECDMALAGGVNLSLHPSKYMLLQE
MKVLSADGKEHTFDERANGLIPSEGSGIVVLKRLSRALADGDHIYGVLRGSSIGHAGTGA
GQYLPNLTVMEETAVRAINEARIDVNELTYIESHGAATELGDPIELKALSNALRRQTQAQ
HFCALGTKANLGHMEAASGICSLIKVLLSMQHGRVSPCVNLQRINTSFEHETSAFVFPRE
AQEWQTNARGSRLAGINAYGMGGSTAFVVVESADALVRLHARQLASREENASAHAQITHT
QIVVLSAQQAERVVAYATELRDFIQQQQQQGRALSLADLAYTSQMGRVMLDHRLAIVATS
QEDLLAKLEGFIAEPGADHSRRETYSGNVHDSKEVSQLIAGEAGKHFVRELVQNRQFANV
ATLWIRGCDIDWSLLHDGEPRQRVPFPGYPFASQPCDLYAALRLDAPVRQTPRQETAALD
AEATASPVVPQAWFAYAVPVDSTSTQDVSTQDDASLQAFWRGLLQADEDVGSLTASALLG
DAAVLDDDAEQPLLSAELHIDPDTVVAMQTCTQRQDIAVETLLTAGWALLINRHARVKQA
QFGLIRHLESDEPRLIPTRIQVVGRHKTAAWLKGVEKQLSQCLEHGGATSEQLAQWGGDV
ALFDSTVALLTDDVAVNPAVSALFATHPSLRLALLVRLEGNGVHVRLVCRGMDIQETQLN
HLLEQFVLLLDGAARHPDKNPAALPMRSKGEGRKAFLKTLEKLNQQDQTP
>A0A086QNT2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii MAS|TrEMBL
MMTRLPLCQQQAPPSLAGCHMLAAFQDIPERPLNRDLKELWAAYGENPFGNVLECWNRSI
PDEDAVVWLNSDGEISETTTFSELFSRITRLSSFLRAAGLQVGDRIILCYPPGTDFVTAF
FACITSGFVAVPVYPPDPSKGLSDVPRFCDINEIAGCKTALTNSLYKRVVQVITTVAKDS
RWRSVHWVCTDDVIKRHAEEAKNSVGPDFPNLSPHHPAFLQFTSGSTGNPKGVIVTHGSL
LHNCHLCWSAYQFPSHYENDGDDENITNHDFALVNQREFWRRRQEISIKSRGHRLRAFSW
LPVYHDMGLIGFVCSPILCGATLYQMSPIDFIRRPWLWLQGMSKYDCICCAAPNFAFEVV
TRKMPDNVYEHLDLSRVCGFLSGAEPIRASTIDRFCEKFGPKGVRRCAVCPAYGLAESTL
IVTARKTFQTVPKLLIVDSFQLQHEKTVVALKPEATVTMDSEEYQVLVGCGVPLEGVQVR
IVDPETKKELPPGKVGEIVVYSSSVARGYFGRPDTTKETFCYSFTDLQGKQTPPLGMRTG
DGGFMYEGELFVAARLKDLIIIRGRNFYPQDIEEAVDKVAMVRPGSSAAFAIEVDGHEAL
AVAAEVRLEEGIKGLWLRVKRQFDRSHYEQIVRDISKSVAANTGLTIHRIWLLRPRTIPK
TSSGKVRRSLTKEKLVSGKLEGILLDHAHHQHQAFYHDGPGGSRSRTRTGSGATPSGGAA
TRDGTASSNPSGDAHPKNSNTSNSITDSSHSVQRGSLRGDACVAGGRLGPSASHGGVHHE
KDHKHRGDGSGMSSPDQVPGAGAAASESSAHVALTEKVKQTVFEAAKTVLGSSEIPEIDA
PLHELGVDSIGAVEFSELISAELQVDVEPTLLFNYPTLSDVIDFFVRELEGKGSEDLAVS
LEKTGARETTTAIIGAACNLPGGTTSLNAFWDLLMCGVDAIAEVPRSRWDVEEYFDPDPG
ADGKAYVREGGFIEDAEMFDAAFFRISPSEAKSMDPQQRLLLEVAYESLYDSGYTREGLQ
RASVGVFVGCCSNDWYQVCSQLELGISSYTTTSYAPSIIANRLSYTFGLLGPSMTIDTAC
SSSLVALHIAAQELQGGSCMSAVVAGVNLMLSPHITVAFCKSRMLAPDARCKTFDASANG
YVRGEGLGSIVMKRLSQAEKDDDRILCILRGTAVNHGGRSASLTAPSGPSQQRVIRTALR
QAELTPGDIYFVETHGTGTSLGDPIEVGALKSVFGASRDAKTKPLILGAAKTNIGHLEGA
AGIAGVLKAMLALRYKHIPPNLHFKQMNPHIDVREFNVVVPTAPMAFPREDGGRLFAGVS
SFGFGGANGHVILQEALQQPSGDKPPCKRHSKRSIICFMFTGEGYEVSCMGRHLYETDDV
FKEIITKCNDILKRWLNVSLLSILYPPADKKMEMDKMMCQARFGHTALFAFEYALAESMV
SKGVKPDVVFGVGLGELVAAAFSGVMSLEEALYVVTQRAKLIDNLPPFEGVMVACRVSEQ
EVEMALSEMEINSRQSISIAAVYGRKNLILSGEQSEIDNVLMKLNIAGRWKYLPVHNVLT
MNLVSDIIPPFTHLMSTVKLCRPKVRLVSSTTGEFVDKEALSGRFWSRQVSQTVQLQQAV
GNIVASGCSLFVEIGPQVVLTKLAQQSLNGNAKDVTWVPAYDTTSDDVRVFENAVMTCNE
AIKIIGKERSLEEGQHGQEELIFHRKPFPWTEIPHPFLSGHKFTEKDDVVFENAFPRRAI
PLIADHAVNGTAMMPGAGMLEMVGAAALALDLRTTSGAVSLENISFERPMLIGAHRVTYE
YNRRHSLGEGGGAGTSPRTVRTPRLVNHAYTRLGFREKSAEKAISETAGPASTEGGRTPV
AGHHHGSYTKAGVLEDIKDYAHNVLRRAAQHAEEIDVHTPVPPSMAPPSIVARHPREGSY
GSMSRTSGIMGSNDRGDGLTVPLSVEMAIRCRVTKMKEVELSTVWDDEVTDHCFATIVIA
DKKQETYSSLQEVRCRCTERMDVNEYYDMLYDAGLQYGPRFRTIQELYRGEKEALARVHF
VGNVKQDPFESGFLIHPAVLDGALQAAGCLLEQSHSGNKVMVPVSVGSATLTKVEVFQPC
WAHVRLEETKSKAATLNVTIYDEVTREVVASLQNAVLRQVDPSASVVATIPKDLLWKVNW
QLVVEGDKEVVGRTPKVLFIGGNIELSEALENAMGSTCKTLSVDALPREKAELQKVLDAE
QWQAIVYVEAVTAGVYDALDVMNAAVRLVQAHYLNLNSGKAVGALWFVTRDTVFRDNGAD
KPGVEIPAHAGLWGLAKAARLEMEVSAGSPISMGCLDVSGADVSSMAQQILHALKSKVLT
MRETEVAVREDGLYVSRLAPQTEVDVRGAIEFHMPERGAISNLVLRPQAFASRLPPEDGQ
IELRVRAVGLNFRDVLNVMGLYPGDPGPPGADCAGVVVAVGDNVEHIEVGDCVFGVAQGC
LRTYVTTDSQLLRRMPESMTFEQAAALPVVATTVEYALHDLAKVKAGDKVLIHAVTGGVG
LVAVQLCKRVGATVYGTCSGGKKDAFAKSMGVQYVSSSRDAKAFAEDMRTFLGEDGKVDV
VLNCLIDDFIPESLKLLGPYGRFMELGKRGVWSKEKVAAERPDVQYELIAVDEMMEKDPI
WFGGMLVRVRGLVAEQKIQPLPMHVFDLADTGENGGVAAFRFMQRAQHMGKVVLKIPSPV
EEASKNGSIVITGGLGALGMVVAGWLAEEGARHICLLSRREEAPQPGEIPGWDWLRTINC
DVQFFSCDVSKYDSIRSVLRTIQTSVAPITGIIHTAGALADALLDSQTPELMKKVYNGKV
QGAWNLNRALEELGLNEQLKLCVFFSSVTSLFGNFGQANYCSANACLDALAQWRRAKGLC
CQSIQWGPWIEQGMAAELKQQVERNGMKGISNEVGLRVLHDAIRQQEKATPVIGCQAIKW
KLFMHRYIEQPPFFTNIEMDLQVTSHDSNTVLRNLPPSERRDYIKAQVAAAARQVLGSSS
PPPFDTPLQDVGVDSLGAVEFRNVLSKKLGVKLSATTLFDYPTLNAIIDHLCEVFGESSQ
KDNLSTKLGALSENDLVQEGMAIVSMSCRLPGNSTCPDLFWDMLMRCTDCVCDIPLTRWN
AEEVYSEDPDLPGKCYTRRGAFIENAEYFDNSFFGISPSEVKHMDPQQRLLLEVAYEAFA
GAGLTKEKLLGANIGVFVGACNHDWTYLIQEDKISAYTGTGSAGSVIANRVSYCLGLRGP
SVPVDTACSSSLVAADFAFEKLMLRDCTMALVTGVNLMLTPHLFIAFSKARMLSPDCKCK
TFDASADGYVRGEGAGAVLMLPYADAKAKQMTIQAVVKGTACNHVGRSASLTAPNGPSQA
EVIRMALRRAGMKPNDLKFMESHGTGTSLGDPIEVNAVRTVFAPGREKTKPLLIGAVKTN
IGHLEGSSGIAGLIKACLVLSRREIPPNLHFKTLNPHINIEDFPVQFVTDFVSLDSVEST
RKKNTAGVSSFGFGGVNAHVLLEEATRDQNATRKEENRPKICFMFTGQGSQYVGMGRHLY
EKEPVFREAITRCVEIAKEYLPLPLLSVIYPSPDERDKMQEAINETLYSQPAVFVISYAL
LELWKSRGVEPDMVMGHSLGEYIAAVCSGVISIQDGLKLVLKRAQIMSRAPSRNGVMVAC
RATAEQVEEAIHTLFGDGEKNVALASVNGLKSVIVSGNQQDVQAVLRQLGAASRAKMLRV
SHAFHSPLVKDTVAPFKRVLETVRLSKPRVMFVSTVTGKVARDELQNTNYWAEHITKVVR
FCDAVQACIAQGAKIMVEVGPRPTLSNMGKGCLPQTTADEVQWINSLEPETLSSAVFDSL
SALAKAGSGAMPAVFDRKFFPWTETCHPLLGGKNTRPDGSVVYSALLRDLVKALFLDHVV
YGKALLPATCLIEMMASATTHMISNHDEEKLVALSQVVFEKPLLVPDETSLSVLVTVETR
GQVRVASQVSNSEEEAEDHAVCQVNIVDALPAAPALTEIRARCKTEIEASQLYAQLHNVG
LQYGPRFQTIVKVFKGEDEVLGLLQAQNVTNFETGFMMHPAVLDGALQLSAVLAFEKGSS
RAMVPFGVDTVLLKSCPPDKELWARVVMNRKGVSSASATVHLYDFDGEPIAVLMGVTLRP
IEFNTAADIPRELLWEVEWESAGSYSMPQDGSLATPSGTDDSGAEDVTRTPSPLVTGENE
NTPSREVPSALPGLSTETPRASKPLSTDETSGAVLNKSVHSVLLVDYAGGHREVVASIRD
TCDVEVEVLSKPGSPELYAQQLRQFAEVVATKTETVPLSTILFLALDEATPAEQLAGGLL
ETVKVFAVEKFKKLPCIWVLTSGAQGPTRSVVSPKHAGLWGLMRTVRLELEMQIGKMVRF
GCVDLDKNLEVSVALHFILQKRTEEPFEAEMILRCPSEDSEKEPGTAEVVNRRERSASFV
SVGPEPVVPSTTDASAKSSVTSDRMALTPGALSCFDETANSTEKLIFNAFCPRLHRSPIP
VRGAVELHMPERGAISNLVLRPQAFASRTAPQSHECEIRVRAIGLNFRDVLNVMGLYPGD
PGPPGADCAGTVVAVGSGVRHLKVGDSVYGIAQGCLRTYVTTNGNLMRRMPESLTFEQSA
ALPVVAATVEYALHDLAKVKEGDKVLIHAVTGGVGLAALQFCKRVGATVYGTCSGGKKAA
YAKSLGVKYLTSSRDASAFAEDMREFLGEEEKIDVVLNSLIDNFIPESVKLLAPGGRFME
LGKRGIWTKAQMAAERPDVYYETIAVDTMMQEDTVWFGGMLDRIRDHVDSGNIPPLPLHV
FEMTDPLAGGVAAFRFMQRAQHIGKVVIRIASDLEVKIPSTTEPAATETAMLAEAGTQGN
ASIGTSTQQIADRT
>A0A099KCM3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Colwellia psychrerythraea|TrEMBL
ELQDLEYDVHAVPIGQPINNIKFYVLYNGQPIPLGAIGELYIGGDGVTHGYLNNDELTND
KFVKNSQQTNQDDIIYRTGDLVRYRHDGHLEFIGRVDDQLKVRGYRIEVGEIEAQLVSHD
KIKEAVVLAKGEGIKKHLVAYYTINQHAPKVSELKGWLKVSLAEYMIPTKFIEVDKFILT
NNGKVDKKSLSEIAYVELGHNDKFSKNNNIEGQLSVIWCEILQLDKISINDNFFESGGNS
LLSIEVQKAVSDRTGYQIELTDIFEYPTIKSLSGYLTKENELDERAVNTKSANTDSTNTG
RQQDNDIAVIGMSGRFPDAANIDEFWQNISSGLESIQTFEDQQLLDCGASVSALNDPNYV
KLGSLVEGMADFDAKYFSFTPREAELLDPQHRFMFECASDALEHAGYGDQSKFRDVGVFV
GTSDSKYMMENLINNPEVLRNAGKMTYYGNSPGFLSTQLSYKLNLTGPSLNILTACSTAL
VGIHQACNSLNFNDCEMALAGGSSISLLKAKGYYFEEGGIDSLDGHCRPFDKDAQGTRAG
SGAGVLLLKRLDKALADKDTIHAIIKGTAINNDAAEKVGYAAPSVGGQTDVIRKAMKKAN
VDASTIQYVETHGTGTSIGDPIEFRALQRAYGEQESGYCALGAVKANIGHLDTAAGAAGI
IKVIQAIKNEQIPPSINFTQSNSQINFDKSPFYINTELKPWHSDNNVRRAGVSSFGVGGT
NAHIIIEQAPVVEPSTSLRDTWLFPLSAMSKSALKVACDNLRNFLQQELQEGSNISLHDI
SYTLQLGRTKHAYSTAFACKSVEQAIKLLQNKPKIVRDKGERPSVVFMFPGQGSQYVNMA
QQLYLTEPLFKTQFDLCAEKLLSISGEQLTNIIYPDAHMIQGVENDNDLLNQTHITQPAL
FTIEYCLARVMQSWGIEPDAMIGHSIGEYVAACLAGVFNLSDALKLVSARGRLMQKVAPG
SMLSVSMTVEQLEPLLTQTGTCLAGINSVSNCVASGSDESLNRLKVLLDEQEIDYRTLHT
SHAFHSKMMDVILPDFKNVIEQITLQPPTLLYVSNVTGNYITPEQVQDPQYWVEHLRGTV
RFADGIETILADREFLHESKILIEVGPGISLSALAKKNPRSAEYTVVSTMRHPKEPVCDM
VNLQNALGKLWGHGITVDWQAFHHEHPGRRVPLPTYPYEKVRYWVNSVKNPQRMATNKEE
KLPMDQWWNLPTWKQKPLIKIDRLLKNLTSSSWLLIMDDSGVAEEVAKSLINAGQRVLRA
YSGKSFSRISDDEYSLDLTNEADYLALLRAACSAAKITRVIHFASIEPVGQNDKYDIEDF
WSDQESGALSALYTIKAIINAELVDDCKIDFITNDVAKISGEEIASPGKATITSLCKVAP
QEYSELECHHIDVKLHHNHGKEYIVSLSQNIIGELLVPERCSSIALRGFQRWEKQYETGV
IEPDMPAAKTLKDDGVYLITGGLGNIGLLLAGYISKTVKNAKLILVGRSHFPAGEDWDDI
MKSQAEESICHKIDQIQIMQARGADVSVLTADVADLVQMQTLFETVEERFGAINGVIHCA
GQLHGSMKALIETGKQDFEKQYSSKVNGVMVLNELLSTRQPDFCILMSSLASVLGGLGFS
AYAAANIFMDAFVQRKHDLGDDSWISVNWDGWNFLSADNVDLSRNSFGMTPEEGELAFEQ
VLAGAYFPQLINSTGSLDYRLSQWIDKTETVHQSVLYERPELDTDYVKPTNEVEEKLVVI
WQNILGIDLIGIEDHFFDLGGDSLVATRVISAIRKVFSVNESIFSIRDFFESPVIEHIAE
KISVSTVDTLVEDKKTQFIEAGKVVDEGVF
>A0A0C5QFG3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pelosinus fermentans JBW45|TrEMBL
MRDFLQYILCEVKSKRLSKIDGINLIRQFQTQISSNKPDFLHPFLHENTSDFSEQRFSST
FTGQEFFLADHVVKGQRILPGVAYLEMVRAAVEQAVRGIKEGELRIRLKDVVWSRPIAVG
EHPLDVHIGLYPEENGEITYKIYRKAITDDVEAVVHSQGAIILTPITEVPVVDLKSIQSE
CSQRSLSSSQCYEAFKAMGLDYGPGHQGIEKVYIGQGQVLAKLSLPYSIVHTQDQFVLHP
SLMDAALQASIGLIGVDTFKLALPFTLQELEIFYRCTPNMWAFIRYSNDSNAEDKVQKFD
IDVCDANGRVCVRMKGFIARIIEWEVNPGRFSENLGTLLLEAIYIERGVVQGAIEPDYTQ
HLVLLCELGGVSRKSIESQMNGVQCLILQAEQEAIGERFQIYAVQVFEQIQRILKDKSNS
KVLIQIVVLGQGEQQVFNGFSGMLKTAQLENPKISGQVIEMESNEDSEQIVKKLKENSCS
PIDNQIRYKDGKRWTIGWNEIEDLQEIVKTPWRSLGVYLITGGAGGLGFIFAQEIVRNVK
NITLILTGRSPLNEKKQAQIKELEELGAQVKYRQVDVTDKKAVTGLIQSIEADHGNLNGI
IHSAGIVRDNFIIKKSKEELREVLDPKVSGLVNLDEASKDVGLDFFILFSSMAGSIGNPG
QVDYATGNAFMDAYAKYRNVLVAEKKRQGQTLSINWPLWKDGGMHVDVEIEKLMLKNMGI
IPMQTSTGILALYQSLTYGKEHVMVMEGNKKRMMERILSITSSPAVVQLEKEYGISNLQV
NSGLLREKTLHQLKVLFGEITKLGIERIDPDEPWERYGIDSVIMIQIIQKLVDVFKNLTK
TLLFEYQTLADLADYLLADYRQECIQWTKLGEKGQVVVEASLDAKGAAPTPVKARGKWIQ
NQQKDKNVKELKQQDDIAIVGISGKFPMAEDVHDFWKNLVEGKDCITEIPKERWDWQEYY
GDSVKEANKTNIKWGGFINGVDEFDPLFFGISPKEAELMDPQQRLLLTSVWHALEDAGNT
PREMSKSPTGVFVAAGSSEYTDAVAIFQNNSLSLTSTAPALLPTRISYALNLHGPSEYYD
TACSSTLVALHRAVQAIHSGECEQAIVGAVNLLLSPRGFIGSDLMGYLSPEGKAKPFQAG
ANGYVRSEGVGVIIIKPLQKAVSDQDKIYAVVKGTGVSHGGKGMSLTAPNANGMKAAMIQ
AYQAAKIDPRTVSYIEAHGIASLLGDGIEINALKAGYQELAASQPQNVEVNTPCYISSLK
SSIGHGEVASGMTALIKTILAMHHKLIPGIPQFTTLSEYISLEESPFKISAENHEWELLK
DIYGNSMPRRASINSYGFSGVNAHVVLEEHTPLKEERIPIQGTTSPQILVFSAKNPEQLQ
ALVRQMLDFVEFQKEISLSNMAYTLQVGREAMAFRVVMVVCDTEELIRSLKDYLESSNKR
AEIESSLPIYTGEVEESHMLIRRLFSGEIGDNIFQLFFAENNMEKVAIYWTQGGVIPWEL
LHEGENVQKISLPTYPFAKEQYWIASNKLQYSPKVLNQQFTDQTQKIINPKNSIQENIQD
YIVQFLSRELNYGQNQIKPNKNIQDYGIDSIMGMKLMRGFEKQFNIHVSGREMLTYGTIK
SLSDHLARKIEELNKQEINVKNELETNSKISKHLNNLGEAQSPLSEGQKGLWMLQKVSPE
TSSYNIPLCFRVFEKVNIDKFKQACHFILEEHPILTSVIEEDSDGVPYQTIESSRPLTFQ
QEDISNLKCSEILSYLREKAKEPFCLENGSLMRVHLLFRSEAEYIVLITIHHIVFDGASS
VLLMTTLLNAYQELAKDRNPIPNSSLASYYDFIEWEHKMLISKEGEEHRSYWRQQLSGNL
PILEIPADRPRFSSRSDIGETYTNLLTPELSKKIKSFAQSQHLNSSIVFLGIFKLLLHRY
TGQEDIIVGMPTMGRIQEGFDSLIGYFVNMIPMRSQVEGTKSFSKFIRELQVTVVDGLDH
AYPFPSLVRDLNIPRTSLNAPIFQVAFLYQNFLHPTGLKEWQSKLPIEFVEGIHQEGEYE
FGLEVYEQEERFVLTIKYNSDLFDLSTITRMMGHYAKLTEEIIDDPSVALEEYSLLSKEE
EITLTDWNETHADYPSDKCFHELFEKQAQKTPNTIAVVYEEGCLTYKELDERSSQMAIYL
QKLGVFPDCLVGICVERSLEMIVGLLAILKAGGAYVPLDPHYPKERLEYMLQDSKASFLL
TQSKLLGKISPLIEGNIKTIVLDKDRHEIEQEVKVEDTLKREVQSNHLAYVIYTSGSTGK
PKGVMIPHRALTNFLISMGDRPGIHSQDRLLAVTTYCFDIAGLEFYLPLINGAQCYICSS
EKAKDVEKLKREIQRNKPTIMQATPVTWTMLFHAGWKNEERVKILCGGEALPERLKQYFI
DTNSDAWNMFGPTETTIWSTVQHIKKEESITIGKPIANTKIYILDNNGKSTPIGIPGELC
IAGDGLARGYLNKPVLTAEKFIPNPFNLVTQLYKTGDLARWLADGNIEFLGRNDQQVKIR
GFRIELGEIESQLKNHPEIQESVVIVNEQEGIKQLIAYYVRTNPGRDKASLSLPKLREYL
KSNLPDYMIPVLFVEVDSIPLTPNGKIDRKDLMNRKIVLTGTKKTFSPPSEIEEKILEIW
KAVLHNDNINIEDGFFEVGGDSLLAVAVAERIKKKLKCDFNVTTLFEYTNIKSISKYIAE
NKDAIAVSYEEGCARHFKQQDAIAIVGISGKFPMAEDVHELWKNLVEGKDCITEIPKERW
DWQKYYGDSTKEVNKTKIKWGGFINGVEYFDPLFFGISPKEAEMMDPRQRLLMTYVWHAI
EDTGITPKEISKGSTGVFVAAGPSEYTDAIDVKNSSFFLTSIAPTVLPARISHALNLHGP
SEYYDTACSSTLVALHRAVQAIHSGECEQAIVGAVNLLISPKAFIYLDLMGYLSPEGKGK
PFQTGANGYVRSEGVGVIIIKPLQKAINDQDKIYAVVKGTGVSHGGKGMSLTAPNANGMK
AAMVQAYQAAKIDPRTVSYIEAHGIASPLGDGIEINALKAGYQELAASQPQNVEVNTPCY
ISSLKSSIGHGEVASGMTALIKTILAMHHKLIPGIPQFTTLSEYISLEESPFKISAENHE
WESLKDIYGNCLPRRASINSYGFSGVNAHVILEEYTHWQEEVIPIQEITSPQIVVFSAKN
PEQLETLVQQMLDFIEFQKEISLLNIAYTLQVGREAMSCRVAMVVRDREELIRGLKDYLN
LSEKGAEIECSLPIFTGDVKESHLVISRLFSGEIGENVMQLFLAENNLDNIAIYWTQGGV
IPWKLLHEGEKVKKISLPTYPFAKEQYWIASNKLQYNPKVLNQQLKDQPQESLINPENSI
QENIQDYIVQFLSQELNYGQELIKLNQNIQDYGVDSIIGLKLMRSLEKQFNIQISGREML
MYGTIKSLSDHLSEKLTELGEQEITVNNQLEAKDQKKNECIEGQGMEALEKFRQGVLTLE
EIENLIDKGEII
>A0A2N9BJM0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces chartreusis NRRL 3882|TrEMBL
MTTRPPGDFTTAIAVVGVGCRFPGGVRTLGSFGRLLSSGPDLFADVPAERWGPERADPAG
GPGTISNGVGVFLEDIDRFDASFFGITPREAGVLDPQQRLVMEVAWEAMADSGRPREEWR
GSRTAVVLGMLAKDYELLHARTLGLDRIGPHHVSGMEFSFAAGRLAYTFDLSGPVSTVNS
ACSSSLLAVHQAAQSLRAGDCDTAVAGGVSLLITPDLSVFLSSVGALSPSGACRPFDAAA
DGIVRGEGCGVVVLKRYADAVAAGDRIHAVIRGSAVNNDGASLGLTVPNAAAQGDLLRRA
LDRAGLAPHEVDYVEAHGTGTPIGDLIEVEALGEVYGAGRTADSPVLVGSHKAVLGHMDA
AAGIGGLLKTIWVVSSGRVPAQPRVERPNPAVDWRGGAVSVPLGDVDLSGRGRPLRAGVS
SFGLSGTNVHVIVEAPPAVEPAAAAPCPAPEDGPRVLLVSAAGETALGEQVAQMRAAVAE
DDVPLGDLVASAATRRTHEAHRYAVVATDRSGLAAALEDPLDPPEGVYTGVVDDPEAVPP
PVFVFSGQGGQWAGMAADLYGSDPLVRETLDECAELIAAEASWSLLDEIRRPTESSRLAQ
TEIVQPAIFSVQVALARWLRERGVVPGAIVGHSLGEVAAAHTAGALSLPDAVKVIVRRAR
LLGETAGTGLMYAVRGSRDQVRDALADIGLPVTVVAVNGPESLIVAGETTAVKETAAALD
ARGMSCRLLRVDAAAHSPLVAHCGPLLERALEGITAQAPAVRLVSTVDPDARDVSFDAAY
WARNFTSPVLLWPAVDGLLAEDDHPLVEIGPHPVLVPPLADAQRRRGRQAPALPVLNRNE
PGPLAAHKALARLHVAGVPVRWERVTGRPHRYRSLPVPSWGGDRYWLPEVPRGRQTASAA
GAPASGGAPARIRLTLLDENDRVTGELWADPGGGTPRSVEPSPVAESRPDTRPGAAPVSS
TAPVSSAGPVADRVEALVREVLGLRDGHRLGRRRGLFEQGLDSLTAVTLRRRLEEEFGVD
LPTPIVFERPTVAALAEHLTDVAPTSATPAATPAAPAAPASVDAVDVGADAVAEADAVAV
IGVGCRLPAAASPEEFWRLLMERRDTASEPPPGRRADPLWDELGAAIPTRGSYVDGIADF
DAPFFRISPREAKLLDPQQRMYLEVAWEALEDAGCPAHTLASRPVGVYAGISIADYQHLI
ARHLTVEDLGLHHGTGTSYAAVAGRLSYTLGLSGPSFAVDTACSSSLTAVHLACQALRAG
ECEVAVVGGASAIVAPSPLVASMAGGGALSEDGRCKVFDQDADGFACGEGAVALVLKPLR
AAVADGDRVYAVLRGSALNQDGATGGLTVPNPSAQADVVRQALDRAGWSPADVDYVEAHG
TGTPLGDPIEVRALAESLGTGRAPDRPLLIGSAKANVGHLGAAAGVVGLLKVVLALSAGE
LPPHLVDRPTPHIDWDRLPVALVDTPRKWPAEGRPARAGVSAFGFTGSNAHVLVEQYVPA
PAPATAPGTAPYVLPVTAATPAALRTAAGRLADALRTGGNDVADVVFTARHRRTLLEHRA
VVVGSDATTLAEALDEVAAGRTTPKTRLGRAVEDEEPSVALFYGTALPSAAARRAFALAT
PGYEAALAHCGDTLNRLLGAPCDLTAEPPAGLGDAFLLAHQSAATSGWYALGIVPAAVVG
VGAGRLAAACAAGQLTVEEALRQLLSGRSELPEDLTRPARVPFLHAPAADTVDWDTVPAT
TAVDVLLGPTPLPHDGIRGDRPALVAAELYAAGYRPAPQPTPPGRRVVSLPGYPWEHRPY
WYREIEPARPVPWLLSGDDEGEMRGRVERLASFLGARSEVGAGSVAAALAGRTAARRRLA
VVGESSGELVEGLESFLSGDPSKGVLEGSAKAASKVAFVFPGQGWQWVGMGVELLVCSDV
FAEAVGECSAVVEELAGWSVVDVLQGAAGAPGFDRVDVVQPVMFTVMVALARLWESVGVV
PSAVVGHSQGEIAAAHVAGVLCLEDALRVVVARSQALVEICGQGAMASVALGRAEVEERI
AQLESVSVAAVNGPASTVVSGGAEEVAGLVAGLVAGGVRARRIDVDYASHSVHVEQVRKR
IEAALAGVAPRAGRVPVYSTLTGEVLAGPEMDGGYWYANLRGRVEFEQAVRRLAQDGFTA
LVECSAHPVLVPGVEQTLETVPGAQVAVSGTLRRDDGGLRRFLTSAGSLWTTGVDITWPV
LLPETQPVELPLDPLVAASGTAPDSGSDDRLERRFWRLVKDGEAGELATLLGLRESRVTD
ALHEVLPALSNWWQERREGTVAESWRYRVTWDRAPRTSRTAALSGTWLVVVPRHLADDEL
VVGSLKALTRYGAAPVPLLVDTRDGDRGGLTELLRSDADSLTEGGEVAGVLSFLPLDESP
HPRHPVVPAGLLATVELVRALDAAPFPARLWSVTNGAFSVAPDEVPAHPVQAHVWGLSRA
AGLENPQCLAGMVDLPPVFDDRAAALLCGVLADPGDEDQVAVRGTQVLLRRLKRAPLPDT
AQPAPWRPEGTTLVTGGTGALGGHIARWLAYHGAPHLLLVSRQGESAPGAAELVAELEGL
GSSVTFAACDAADRDALARAIDGIPAEHPLTAVMHTAGVVDDAPVNEMTAGQLERVLRPK
SGAVANLRELTGKFDLSAFVLFSSAGSLLPSVGQGAYAAGNAYLSALAAHLRAEGVPALS
VAWGAWSGGGMAGKEDFARFISHRGMDLMTPHLAATALQQALDHGDTDVMVANVDWARFG
KVLNAIRPHPMVSELVGGPARAAAADQEQQPALPARLAGLAPQQRLDTLLDLVCAEVSTV
LGYARTERVVPGQAFRDLGFDSVMGIELRNRLNKATGLRVSPTAVFDHPTSEALARHLLD
ELATGSTPFTETGGEPVNGTPATASPVARHAPSAGSEIDSMSIEEMIRMARGDRPDPVDE
SE
>A0A0N0NEH7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MTTDFRDFSVLQNQDDESVESWRTRLAELPPTAQYAALLELIKGRISVVADRAEAGAEAG
VVDARAPWRRLGVYRDVAERFRDALADATGLRMPATLLFDRPTPHALVEHLRGELLGDPA
GTEAESASPTAEGPAAALDTDPVVIVGLGCRLPGGVDSPEALWRLVDEGQDVIGPLPGDR
GWDLDALYDPDPAQHGTAYTRHGGFLDGAGEFDPGFFGIGPREATAVDPQQRLMLEISWE
AMERAGVDPHALRGSRTGVFTGVSLQDYGPAWHEAPQDAQGQMLTGNALGVVSGRVSYTF
GFEGPALTIDTQCSSSLVALHLAAQALRTGECDLALAGGVTVMSTPGMLLEFSRKRGLAP
DGRCKAFSADADGTGWAEGAAVLLLERLSSARRAGRRVLAVLRATGTNQDGASNGLTAPN
GPAQTRLIRQTLAGARLRPADVDAVEAHGTGTALGDPIEANALIAAYGKDRPADRPLYLG
SLKSNIGHAQAAAGAAGVIKLVMALHHGVLPRTLHINEPSPHVDWSSGAVELLREPVPWP
RTGRPRRAAVSAFGVSGTNAHAIVEEAPEPVAVAAPAVPLAVSARTEPALRAQAGRLAAH
LAERPELALTDAGFTLAARTRFEHRAIAVALDRDDAVRALEALAGGGGAPGLTYGGVRPE
VADGRLAVLFTGQGGQRPGMGRRLYAAYPVFAEALDEVCTRMDVHLRRPLREVMFAPEGS
ETADLLNETAYTQPALFAYETALFRLVESWGVVPDVLIGHSVGELTAAHLAGVWSLADAC
ALVAARGRLMQACRAGGAMAAVQAGEAEVLATLAEFGDRVVVATVNGPTATVVAGDADAV
DDVVALWRERGRRTKKLTVSHAFHSPHMDDMLDAFRETAARVTYRPALLPVVSNLTGRIA
TDDQLASPDYWVRHVREAVRFLDGVHCLHEQGVTAYLELGPDAVLSAMGPGCLPDQDALF
VASARAGRPEDTTLLTALAQLHVHGVDIDWRALYDGSDATHVDLPTYAFQRRRYWLEPTA
VRPPQAAPRVSDPAQWRYRVEWRGVTPPPSAVPPTLTGTWLLPIPPGGADESLVTRLTWV
IERLGGRAVPLPLTAADADRGRIAELLEKQLADAGGEFGGILSLLALDSTVHADHPAVTD
GLALTCALAQAHADLETPAPLWCATRGAVAATDGEPVDEPGQAMVWGLGRTLALEQPRGW
GGLVDLPADLTDDALLWFGAVLTGQDGEDQLAVRESGLYARRLVRATAAEAGTRAPGDLA
WRPRGTVLVTGGTGALGAQVARWLAAHGAERLILTGRRGPDTPGAPELVRELAGLGPRIS
VEACDMADRRQVERLLASIPPGELTAVVHAAGVIGRTAPLTGSDLAEFADTVAAKAAGAA
HLDAALGDTELDAFVVISSISATWGSTGQTAYAAGNAYLDALAVNRRARGLAATSVAFGP
WGEAGMGAEAGMREFLTRRGLPPLAPAEATAELWRAVAAGENTLTVADIDWDRFLPPFTA
TRAARFFDDLRPRTTAAEAPSAQEAPRFTDPLLTVRTEAAAVLGHGSPEDVFPDRRFLDL
GFDSLTSVELRRRLIAATGLQLATPVVFEHPTPAELARHIGELAAAGRQGDTSGPVDDGG
GTGVRHLYRRACEIGKFTEGIRVLQAAAKLRPVFEDAEEFGRRQELVRLASGPNGPALVC
VPSMVAPSGPHNFARLALHLHGRHDVFALPLPGFGDGEPLPATSELVVDLHADAIARELG
DTPFALAGYSSGGWLAHAVAARLETLGHSPRGVVLLDTWFPKDDIPEEQIQEQLQGIAVN
DHAFALITEDQVTAQGAYLELFDGWKPGPVAAPVALVRAGERMPQRAHTDTDAPRNWSAE
WDFEHDTLDASGNHQTMMNEHAADTADAVSGWLLGR
>A0A6C0QC10|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. S4.7|TrEMBL
MANEEKLLDYLKWVTADLHETRRRLADAEAGRHEPVAIIGMGCRLPGGVRSPEDLWRLVS
TGGDAVSRFPRDRGWDVEGLYDPDPERPGHTYVKEGGFLYDAAHFDPEAFDMTPREAAAT
DPQHRLLLETAWETFENAGIDPLSLRGTDTGTFAGVMYSDYATQVGKALEGYEGHISIGS
APSIASGRVAYSFGLEGPAVTVDTACSSSLVALHLAAQALRNGECSLALAGGATVMCGPG
IFVEFSRQRGLAPNGRCKPFAAAADGTGWAEGSALLLVERLSDARRNGHQVLAVLRGSAV
NQDGASNGLTAPNGPSQQRVIRQALSHAGLSSADVDVVEAHGTGTTLGDPIEAQAILATY
GQGRPDGQPLRLGSVKSNLGHTQAAAGAAGLMKMILSMRHGVLPRSLHIDAPTPHVDWSA
GSVELLTENTPWPGGGEQPRRAGVSSFGMSGTNAHVVIEEPPAPAEPPAAPVRPAGPVTL
RLSGHSSAALRAQADRTHRHLTDHPDLELPDVAHTLATARATLDHRGAAVGETRDDVLAA
LRGLADGSPAAVSGRAVAGRLAVMFTGQGSQRPGMGRELYARFPVFAAAFDTVCAALDPH
LDRPLRDLVLAEPGTAAADEAAEPLDRTQYTQPALFALEVALYRLAESFGVRPDHLIGHS
LGELTAVHVSGMLDLPDACAFVAARGRLMQALPEGGAMAALQVAEDQILPMISGRAHQVG
IASVNSPDSTVISGERSAVEEITAFWEVWGHSTKRLRVSHAFHSPLLEPMLYELTEIVSG
LTFRPAAIPVVSNLTGKVLSTEEAASPRYWADHVRHTVRFADSIAHLAQQDVRFYLELGP
DGTLTGLTYDCLTSGAAPSPDAAVLAAALRPGEPEAMTFTTALARLHASGAPIAPDTDGS
GTPADEHRPPGGALVPLPTYAFQRRRLWVDPPPGPRPRTVSAGDTPFWAAVENEDLDQLA
ATVHADDEQRAALAALLPALTGWRRAQDGRYRLRWDPVPDPVPDAGDHSAPGNWLAVLPP
ALATADAADVLTGITGALTAHGHRVVAFVADPDGEPSPAELLRAQLAAGAPDGTPFTGVL
SLLALDERPHHDHPAVSVGTALTAALVQGVAAAARPVPVWGLTRGAVAVEASDGTRPEQA
PVWAVLQAAAAELPTWSGGLIDLPGTLDDDAGRRLAAFLRGSAEQQVALRPAGLLARRLS
PLPTDGSDVWQPGGTVLVTGTDTPYGAHAARWLAAHGAEHLVLLAAEAPTGLAETGVGLT
LWPYDPTDGDTDTDHDALAALLADAPVTAVIHTTGAAHTDPRTALATAHHLDRLTRDRDL
AAFVVFSDLSGTLGLPGTGAQAPLHARLEALTDARRAAGLPAATLAFGPLTEEPHLALLG
VRPLAPKPAMDVLGRIPARGAATTVVADIDWARFTAEPNNAPLALLREIPGARTPAAHDG
TGPAGADRDAEGERLRARLAEASDDEEARAVLLDLVRDCAADILGHHSADQVGPEDNLAE
IGFSSFSALQLCTRLNAATQLTMPTVVVYDHPTPAGLALHMHGRLAATAHPAR
>A0A1V2RBK0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MSTVSQEEKLLAYLRKATTDLQKARRRITELESGRDEPIAIVGMACRYPGASSPDALWQL
VLEERDVITDFPTDRGWDLDNLYDPDPDKPGRTYVRQGGFIESATRFDAAFFGISPREAV
AMEPQQRVLLETAWEALEGAGIDPASLKGSRTGVFTGLVEQSYLSLENPGEFDGYLMTSM
LSSMASGRISYTLGLEGPAVSVDTACSSALVALHLASQSLRAGESDLALAGASYIAATPL
GHIDFSRQRGLAADGRCKPFAAGADGIGWSEGVGLLVVERLSDARRNGHTVLAVVRGSAM
NQDGASNGLTAPNGPSQERVIRQAWANARLGGADVDAVEAHGTGTALGDPIEAQALLNTY
GQERPEDGRPLWLGSLKSNIGHAQAAAGAGGIIKMVQAIRHGILPRSLHAEEPTPEVDWT
SGQVELLAQARPWPRTGRPRRAGVSAFGASGTNAHVILEQAPPAAETPDERAPADATAPP
VPWVLSAGTPAALRDQARRLLAHVTEHEDLRTADIAWSLATTRSALGHRAAVTGAGREDL
IAGLHALADGTASPHLVQGNAAQAGRTVFVFPGQGGQWPGMARELMDTSPVFAARIRACG
QALAPHVDWSLEDVLREADGAPSLERVDVIQPVSFAVAVSLAELWRSYGVEPTAVVGSSQ
GEVAAACVAGGLTLADAARVAAVRSRVTTALAGRGGIVSVGLSRDELTALLRRWDGRLSV
AVVNGPGSTVVSGDHDALAELVEHCREHGIRTRRFSADYASHSAQVEEIRDRLVRDLTPI
RPRRGTVPFYSTVTAGPLDTAELDAEYWYRNLRHPVEFERTTHVLAEHGHHTFVEVGPHP
VLAPVLQENPEAAVVVGTLRRGEGGPERFLASLGRLWAGGGTVDWSTAFGGHGARTVPLP
TYAFQHERYWYAASGTGADVGRHGLAPVGHPVLGAAVAVAGTDQTLFTGRVSARTSTWLG
GHTVLGTALLPHAALAELAVRAGDEFGLTAVDDLTVETPLVLPARQAVQLQLRVGPPDDE
AGRPFTVHARPDEGDVTWTRVAGGRLSPRGAGPWAGPAAWPPPDALRLPPAEVRARLTAE
GLPEGPVLAGVTAAWRKGEEVFAEARLPDELRETAAGFGMHPVLLESALATVLLTLDAPR
EGIARLVRHGGGFRLHATGATALRVHAAPAGDGAVSVTMTDPEGRPVATAGPLTFRGVTA
EELGGTGARHHDDLFHVGWRPVALPRPEVPLRWAQLGTNRFAAEHLPDVAAARKAADSGE
AMAGVFSWHGPAPDGDVVSSVYGATHRALDLVRDWLADDRLGTTPLVVVTRGAVAAGEED
VRDLAGSAVWGLLRTAQSESPGRFVLVDVDDEEASAAALPAVVASGEAQAAVRGGRVLVP
RADRVGPPDAKTAPSGAWNPHGTVLITGGTGTLGALFAHHLAAEHGVEHLLLTSRSGPDA
PGADALRASLEALGARVTVAACDTSDREALAALLAAVPEDLPLTGVIHAAGVLDDGLITA
LTPERLNAVLRPKVDAAWHLHDLTRGLELSAFVLFSSLAGVIGSAGQANYAAANSFLDAL
AQHRRAAGLAATSTAWGLWEQLSAMAANLDQTDVDRIVRTGFRLVASDRGPRTLDTALAL
GHAAVVGVPVDMATLRQRPAQAPLVFSRLARSPLRGTVRENGMNAETLAALLAGLPEAER
HRTVLDLVRAEVAAVLGHPDPAGIGEEQPFAGLGFDSLTSVELRNRLGGVVGRRLPASLV
FDHPTPGELAAHLLGELRPADADQDAAQPTDYAADIRLADDIRPADEVVRVAEDPAEVLL
TGATGFLGAFVLRDLLRTTSATVHCLVRAADEAGGLRRVLANLEWYRIRDEVDTGRLRIV
VGDLAEPGIGLAAERFDALARTVDAVYHCGASVNWIHPYPTLKAANVLGTEELLRLAARH
RTVPLHHVSTTGVFAGPVTPGVPLAVTDPTGPGEALPNGYTQSKWVAEQIVGLARERGLP
VNVYRVDQVAGDLRNGACQTRDFVWLMVKGVVQSGAAPKALPGLFRLMPVDYASAALVAV
SRRAASAGGTFHLGNESHVTMDDMVAELRSFGYRPAEVDPADWIDLVRADPDNAIAPLLD
AVEMLVEDSESFYPATDTARTAAALGGSGITCPAASASLVRKQIRFFAESGWFPAPEGS
>A0A1V2RCI9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MSTSADEIIEALRASLTENEQLRHQNEELLASAREPIAVVSMSCRFPGGATSPEALWRFL
LDEGDAVSGFPENRGWPPDSGHGAEAAFLSDPDQFDPSFFGISPREALTMDPQQRLLLET
SWETLERAGVVPATLKNSLTGVYMGATATTYTQGATEEVKGSEGHLVTGVGFYSIAGRLA
YTYGLQGPAVTIDTACSSSLVAIHHAVQALRAGECTLALAGGATVLASPEMFVGISSLDV
LTFSGRCRAFAGAADGTAFSEGIGVLLLERLSDARRNGHNVLAVIRGTAVNHDGPSNGLT
APNGRAQRRVIQQALANAQLTPDQVDAVEAHGTGTTLGDPIEAHALLATYGQQRTNGEPL
WLASIKSNIGHTLAAAGVAGVVKMVEALRHGVLPKTLHVDEPSPQVDWSTGDVRLLEDTR
PWPEHGRPRRAGVSSFGISGTNAHLILEQAPEQAVPSTAEQADEGRLRWQTPVVPWVISA
KTEAALRAQAERLADFATDRPDLDIAAVGAALTRHRAAFDQRAVAVAADRGELIASLRAL
AADEPAPQWTRGAVGKPSRVVFVFPGQGAQWEGMGRELLATSSDFAAAIADCEAAFAGQV
DWSLTEVLTRAPGAPDLSRVDVVQPVSFAVMVALAAVWRAHGIEPAAVVGHSQGEIAAAH
VAGALSLKDAARIVIRRSAAIVRLAGRGAMASVNDEPDAVAARIAPWGGRLSLAAVNGPR
ATVVAGEPAAVSELLAACEADGVRARAIAVDYASHSPQVEEIEQEIREPLADITPIASPV
LFCSTVTGEPLGTAELDAGYWYRNLRQPVQFETAVRHLVDLGHHTFIEVSSHPVLRLGLT
ETFEQAGAPAVALQTLRRDSGGPRQFLLAMAEAHTIGLPVDWEPVLPAPPVGLDLPTYAF
QRERYWIAPSSARVGDLGSVGIGEAGHPLLSALVALAEGDTVVLTGCISRRAQPWLAGHA
VGGTVLVPGAVFAELAVRAGDEVGHEHLHELTLETPLVLDEHTEVQIQLRVGPPDGAGGR
PVSIHSRDRAATGVPWTRHASGILTDAVGAVSPEPVDGTWPPTGAQAVETSGFYQRLAEA
GYQYGAAFRGLRAAWRRGDEVFAEVELPEEQREEAAGFGIHPALLDAVLHAGLLSAAGRD
GADDDAPVQVHLPFVWNRFALSATGATLLRVRAVTAEDGALTVSATDPVGRPVLAVDSIL
TRPAELGGSDRLSQDLADSLFRVEWTDPGATAGGALEADIAVIAPRDSGLVPDLGAAPVH
EDLAALAAAVDGGRPVPDTVLLPCPPPRTDADSLPDPARVQAAVLDVLGVLQDWLADERW
GESRLVVVTRGAVGLAAGTGVEDMAAAAVRGLVRSALAEHPERFGLVDVGADGAGWDTLG
AALALGENEVVAGEDGRVLVPRLRRMGSGGGLVLPGSDGWQLEVGRSGSLDDVTLVETPA
AWDPLGPGQVRIRVRAAGLNFRDVVVALGMLPGQDDTGAEAAGVVVEVGPGVERLAVGDR
VMGLMPGAFSSVGIVDERLMVPVPPEWSWDVAASLPIAFATAWFGLGDLAGLAAGQTVLV
HAGAGGVGMAAVQLARWWGAEVFATAHPSKWDVLRGLGLDDDHIASSRELGFEEKFRTVS
NGRGVDVVLNSLAGEFVDASLRLLAPGGRFLEMGKTDKRSDEQVAVIRTDVAYRAFDLPE
AGEDRLNEILRELVDALGQGHLTPLPVRARDIRRAPEVFRWMAQGRHVGKNVLRVPGPLP
AAGSVLITGGTGTLGRLVARHLIERHGVGHVILVSRRGADAPGAEELRKELEELGGRVTL
AACDTTDRDKLAALIAQIPEDLPLVGVVHAAGVLEDGMISTLGPDQVERVLRPKLDAALH
LHELTADMDLQWFVLFSSAAGLFGGAGQANYSAANTFLDALAYHRQSLGLPAVSLAWGHW
GQASGMTGHLTEADHKRMARSGIVPITNEQGLALLDAALRTDEPLLLTAVLNLTAFGGGE
PQQIPPIVRGLVRPARRQAAGEEASFADRLASLPAAERAQQLTDMVRAQAATVLGHGAVQ
AVDPERGFTDLGFDSLTAVELRNRLTAATGLRLPATLIFDYPTPAALAGMLLSQLAPADT
TSSEASQDFGEADIRRALATVPFEQFEKAGIADILIRLARGEDHAGDDGAPDQSKESIAA
MSADDLIHLVLGDTES
>A8L9E9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. (strain EAN1pec)|TrEMBL
MDSTRPEQGHSGATADQARDAWRARLAELSPPAQIEALLDLVVDHVVVVTGSHGGSAGVD
RGAPWRALGVYRRIADVLRAKLTAATGVRLPATVLFERPTPKAVASFLHAEILGVREEAA
DTAPAPTPAAPAEGGGRGADPVVVVGMGCRLPGADSPEALWELVAQGRDVVAGLPTDRGW
DLDGLYHPDPEHPGTAYTRQGGFLPGVSLFDAGFFGIGPREATAMDPQQRLMLEVSWEAF
EHAGIDPHRLRGSRTGVFTGVSLQDYGPPWHDAPAELQGHLLTGNALGVVAGRVSYTFGF
EGPALTVDTQCSASLVAVHLATAALYAGECDLALAGGVTVMSTPSMLMEFSRKRGLAPDG
RCKAFSADADGTGWAEGATVVVLTRLSHARARQLPVLAVVAGSAVNQDGASNGLTAPNGL
SQQRLIQQALANAGLSAGDVDAVEAHGTGTPLGDPIEARALLATYGAGRSPDRPLYLGSL
KSNIGHAQAAAGTAGMIKMIEALRHETLPASLHITVPTPHVDWATGAVTLLTQPTAWPAT
ARPRRAAVSAFGVSGTNAHLIIEEPPGPARIPAQATPAAAPAGATEDRDAVRGGDTPEWA
ANLPTTVILSARGDEALRAHAARLADHLAGHPDVTVDDAAHTLGARAQFPTRAAVVLDGP
PTERASHLVRALTTLAAGRAAPALIRGSTPVDLAGARIAMVFTGQGSQLHGMGRRLHAAY
PAFARALDAACDRFEPHLDEPLRDVMFAAPDTPPAVLLDQTLYTQCALFAYQSALFRLLE
SFGVTPHLLLGHSVGELTAAHIAGVWTLSDTAALVAARGRLMQSCVPGAMAAVGATEDEV
RRCLDEYGGRVDIAAVNGPTAVVVAGDSDAVGALAAHWAEQGRPTRGLAVSHAFHSAHMD
PVLDRFAAVARTLAYRPPAVPIASALTGRLSTDPDAPVDLTDPAYWVRHIRETVRFHQAV
TRADAENITSYLEIGPKPTLTPYLGDARVVTAARRGQPETTALHIGLAELYTHGTPVAWR
AANNPRAASRRPAHRHLPTYPFQRRHHWTDPTRRSGAPGAPGPEGWRYRISWRSRPVPST
GALPGMDGTPPPLTGRWLLLLPPAGVTDEEVSRVSWIVERLGGTVLRVPLRHEDTDRARL
AARLRALGQPGATTGRGGVLSLLGLDTTRHPDHPALTTGFALTCALAQALHDIELDAPLW
TLTRGAVRTGAAAATAASDRILDPAGALLWGLGRSLALERPGAWGGLVDIPAELDDSTLG
WLGAALTAPDGEDQFAARPAGLLVPRLVRETTPVTTAPWDVRGAVVLITGGTGALGTRIA
RRLARDGARRLILASRRGPDAPGAAELCAELTALGVQAVVRRCDASAAAAAGTGTGTGTG
QLAALVRELAADPEAPLTAIVHAAGVDGPMAALPELDLGQIAAVLAPKAGAAELLHEAAG
TIPLVFLSSVSATWGSGGQAPYSAANAYLDTLAAFRHASGRPATSVAFGPWAEAGMGAEP
ARRDYLHRRGLNPLSPGRAIDALAQAVGTGCPGPVTVADVDWARFLPAYTAARPSRLFDE
LRATADEAASPAADGTQPADLTGAPRGDGAEPGDDLAALPAAEQGRALRELVRAEAAAVL
GHREADEIETGRRFLELGFDSLASVQLSRRLAGATGVALATAAVFEHPTVADLADHLHAL
LAGRPAPAAATTGADGAVGAVGAVGSGTRTGTGWTSTSASAAGVPAVGGAEPVGVRGLYR
QACADGKFAEGVGVLRAAAKLRSTFTAPSELARRPRPVTLASGPAGPALVCLPSMVAPSG
PHTFARLALHLHGRRAVHALAHPGFGDGELLPATADLVVDLHAETLAAHFPDTPVALAGY
SSGGWLAHAVAARLEARGIRPSAVVLLDTWLPGDRIPEADIAEELRGIAVNDQAFALMTE
SQVTAQGAYLDLFEGWKPTSVRAPIVLVRAVQRMPGQRADPAGPVTGWADEWDLAFDTRD
TAGDHQSMMNEHAGSTAHTVHAWLGDLHARRSPARTVASGTAIR
>A0A2C9D6N8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Hartmannibacter diazotrophicus|TrEMBL
MTLNDIAIVGYSCRLPKASTADEFWGLLDRGECVISEVQPDRWSKRRFGHPGQGVVGRSY
TWAAGQIEDIWGFDPVFFGISPREAEQMDPQQRLLLQVAWEAFEHSGIRPSDIAGTETGV
YVGASGMDYSHSLIVDTGSGDTQSMTGSTLSIVSNRISYIFDLRGPSFTVDTACSSSIVA
MHEALEAIRAGRIDTAVVAGVNVLLSPFAFVGFSRASMLSPTGLCRAFDAAGDGYVRSEG
AVAIVLRRADVARAAGNPIRSLVVGSGINSDGRTAGLSLPSTEQQAALLEQVYERFEIDP
RSLAYVEAHGTGTRAGDPIEANALGTILGRRRTSPLPIGSVKTNIGHLESASGLAGLLKV
QLALEKGRLPASLHFNTPNPDIDFEGLNLEVVSEGRLIVGEGPHHIGINSFGFGGANAHV
VLKEAVPTMASERPEFQAPLVVSARSREALKALAERYRDRLDAANDGEARIIANAAAYRR
DHLDYRVVVPGDRQSDLVKGLDAFLAGERSAISAQATARNGKVAFLYSGNGSQWAGMGMA
AYQTDPDFQQAFETINRLFMRVAGWSLLTTLFSEDLENDVERTEVAQPLLFAIQVAMTQA
LARRGLRPDAVAGHSVGEVAAAWACGALSLEQAVELIHVRSTCQEVTRHLGGMAALLVSA
DQAREALSLPEFAGLEIAGDNSPRSVTLSGSYDQIDAFAKFARKKRWAMRKLKLDYPFHC
ALIEPIRNNIVDALSDLAPTDGPVQFISTVSGRSLDGRELDGEYWWQNVRRPVLFRAAVE
ELAALDMRVFVEIGPKPVLQNYVADSLAAIGKPGVALASFDESDRVGEDVIGGIATRAFA
NGASIDMEKLFGPALPLGIDLPVYAWQNQTYRPVASDETFDVFGHDDDHPLLGSRSRFNT
GPYFSFIDTYLVPWLADHKVEDATVYPAAGFAEMALAAARQEFGPDSMVEVLDFDILRPM
LIEDGSTRETRVDIDMAHQVIEIGSRRRLSGDDWALHVRGRVAKAPVQTAPRDERTVPTG
TPSLSSEDLYLQTQRFGLNYGPAFRRAKGVYEIGERSIYVALSDAAAGDVGDSQFSLHPT
LLDASFHGLFQLITRLVAPVAGTSFLPVRIGSLRLFAAGATPVGAFIDIEKASSHSVVAK
FTLIAADGSVVAVADGCRFKSVHLTRPDHPDEFAFRVAALRHIEPGEVVDAGEAWEAATL
GRAQALGLVASDYGEPDDADLLIDAASRSLAFSTLERFASDDRRLDPVALAGDGRLHETA
LPLLGRILDAVLEDGAAECSQDGIWTLAAESPYPALSTVIQALLGDHPKRIAEVAVLSRL
STSLEQILTDGLEDGNDPRLSAGLTDYFATGSQTGEALIQAASTVAEDLLGTWPDCRPLR
ALVLGRGASHVARLLAQGGDKVTRVVVSDADPHKVERLKLRLEGEPQIEVLTIDELNEAS
AFDVVLSIGALATPSRDDIASKSPELLAGGGLFISAEPEPAFFADLVGGTATDWWRDTLV
GAHPIGPVAGAEALTARLIEAGFETADWGPIALAGSQTSLLVAKMPTKSAATQEELVDPV
LIVAVGNDALSKALADALSSDLSRRDRKVLLAVGDMDETGAGRLDAVGSDSDGGLKDLLA
AGSAKDLVLLPAMRPISGWPTKVVLRATMVIHAILNGAMKPPARLWLVAPGGAGVASHDP
VSAALWGLGRVLINEYPDIETRLVDFSPTMAPAEAATRLGRLLANPGDEREFVLDLQGSS
VLRVVPAKGFASRAERNRLTGECGMVLDLEHQGSPDGLAWKAVERHAPADDEIEIEVAAT
GLNFRDVMWALGLLPDEALEDGFAGATLGMECSGVVTRVGPTVTRFVPGDRVITFAPACF
ASHVKVAEKAVAPVPAQLDLEAAATIPVTFLTAYYALVDLARLEEGETILIHGGAGGVGL
AALQIAHWRGAKVIATAGSPEKRALLDMLGAHHVLDSRSLAFHDEVMQLTGGDGVDVVLN
SLFGEAMERSIAVLRPFGRFVELGKRDYYANSRIGLRPFRQNLSYFGVDADQLLTRRPKL
ATRLFDDLVKRFEEGVFSPLPYRVFDADRITDAFRLMQQSGHIGKILVRPPEMMPAPGQR
PTPIHADATYLIVGGLGGFGVETARSLVERGARHLALVSRSGTVSETAGAVIADMESAGA
EVRVYACDAAERPQVDKLFETIAKEMPPLKGIMHTAMVIDDALFQNLDATRIESVLAPKI
AGASNLDAASRGLPIDLFVLYSSATTLIGNPGQAAYVAANAYLEGLARQRHAAGLPALTV
AWGAIADVGYLARNAEVNAMLSMRMGAQALTARQALKGLHLALDAGLDDPVIAYARMNWA
SAKRELAIMATPLAEVVMRNVDDSVAASTGDGELGRQIAELPQREAIKLVCDILADEISH
ILRLPLEDIDPVRPLTEIGMDSLMALELRMAAEQKLGFDIPLLSLANGATLSAIATRVVE
RVQGSEGALSGDAEIVAARHVAEDEGIDVSAAMSAIEERSAETKRLI
>A0A3E2MS25|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium marinum|TrEMBL
MSAVAYRLPDGTIPVLLSADTPELLDSEATALRDHIAAHPDLTPGPISAMLFRTRAARRH
RALAMVRTRAELIDALQAMIDRYEHPALIRTAPAAIRRRIGYVFPGQGGQRPGMGQLFYE
SVQAFRAEVDRCAQAFEAQSCGSPRNYLLDKNFQDDGSAGIVQPALFTQMAALAAMWRSF
GIAPNVTIGHSQGEVAAAYVSGTITLDDAVRVIGIRAHAADEFAAADYAMAIVAADRETC
EDLLARCSGWAQLSVVNSPRMVGISGERETVQGIVDTLTERGTFARVIRVRYPAHTSLIH
DGADKLRAAIQDQLQHPSFVDTDIDCLGATLGAPITSELPVGDYWFWNLRNIVRFDKAIA
AAVQRDVETFVELAEHPTLQLAIHENLAALHDEADDRPAMVVGTSERTATDLGEFTRNLA
QLAVHDLNYPWECLRAEPDGAQGLPLLDFPNTRMNEIRLWLPYDEVLPRRQPPSVSVAPA
PPSVPGATADTTPARLLVEEWVRLSQRSLTPPRVVGIVDPTGACAQLATAMTTAAHQAGA
TARVVNGENDGTGADVNTLVILLPETPKLDGRAAATEVGGFFSNRAWWPGVDTGVTDCWL
VTVGGEAATAGDGPPDPVHAAASAGFRSIGAEHPGVGFRHLDLPAGATAQDWAHPIVAAL
HTANEPELAYRDGAFYAKRIVAGEGAVVHGADACPEHVLIIGGTGNLGLEFCDHFAHRGA
RRITLVSRSGESAAVAERLAQIRSATAAQIAVTRCDVGDPAAVSRLAAQHRSTPADLIIH
AAVAYASVEFSDITTDDADNALYAKVVGIGQVLDAFPRTDGCRIVLCSSARATIGGRGQV
MYAAANRMLDAMAHRLRAEGLDCVSVQWGQWTVHFDLDASSMAQLAAIGVIPMPPAEAIA
LGMQRLGRNAIVAAFDFDRARPVLETFGYGPLVSELLSPVSETAAPAEPADLPGRLSNLL
ATAIGAERAERIDTSVPMVALGLDSLQALELRRRVKAEFDHELEVSDLLGGASIADVLAQ
LGAR
>D0LQX5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2)|TrEMBL
MVALKRAREQLEANERQRSEPIAVVGLACRFPGGADDPERFWRLLERGVDAVGEIPAERV
PAHPAFPQTVSSAALLDDIEHFDAEFFGISAREAERLDPQQRLLLEVAWEALETAGHAPS
GLVGSRTGVYVGIGSPDYLRRLLRESPGAVDGQAFTGSLASVAAGRLSYILGLQGPCMAL
DTACSSSLVAVHQACASLRSRESDLALAGGVNLILSPESGYVLGQLKALSPDGRCKSFDA
RANGYVRGEGCGVVVLKRLSDAQRDGDHVWALVRGSAVNQDGRSAGLTAPNMLAQQAVLR
QALDSARVEPAAIGYVETHGTGTPLGDPIEIEALTAVLGQPRADGSRCVLGAVKTNIGHL
EAAAGMAGLIKAILTFRHQAIPRNLHFQTLNPRISLSGTPFVMADGEQPWRAGERPRLAE
VSSFGISGTNAAVILEEPPTQPAQAPALTDQTPAPARAHQVVTLSARSPQALSGAVARLA
AHLRSEPAPALADLAFTTRAGRAHFAYRAGFAASSIAALREALDAWLTADAAGAADAAAG
APDVAGRPRIAFLFTGQGSQRAGMGRALYDAEPVFRETLDRCAALLDGALPRPLLEVMWQ
DDSAELDQTLYSQPALFALEVALTAQWRAWGVAPDVVLGHSLGEYAAAAAAGVMSLEDAC
ALVAARARACHGLGPGGAMAAVEGEPAVVEEVVAAIAGDLVIAAHNAPRNLTVSGPADAV
QRAGEELRARGAKVKPINASCAFHSPLMAPMVAAFAERAAQVDYRPPRVAWVTNVTGERA
GEGFDAADYWREQLCAPVRFVECVRQARALGCTVWVEIGPGPVLLGAVSRTLDEPPSAAP
SLHRERDDGAAMARALATLYTRGVALDWGAYDAGAAHRRVPLPTYAFARERFWLSPSAAP
AAASEPALPRSAGAGHPLLGTRAALPGREVHYLNRLTAAHPPELGEHRVYGQVVAPAALY
LAAFLAALDERGGGALVDVAFTRALTIPEGGDAGAEGASVCVALTPDEPGARLSFFAAAE
RGSQPAGQGEGGEAWTLHARAALAPAGDAGTDAALASADLAALRARCPRAAAPAELLAAV
WTEGAAARTSAIHLGPRFRRMAALWLGDAEALTRLALDPAALDAAAADEAAAGAVPLTVF
DSCFQLLGLAAAASEAEQAWMPIAIERVELHAGAALAAELWAHAAAAVVGEGALIRGDVR
LLTAAGEPVATLSGVSLKRVSQAALLQPPAWRRWLYELDWRRCEPPAEAAAAAFAAAELA
VILDRGGRGARFADALERRGARVLRCAALEELTREPRPALAHIVSFAALDAAKTDDAADA
DDAAPSAHALALVQTVSRLRGERAPRIWWVTAGAQVVAGAPAAPSPAQAALWGLARCAAL
ELPEMWGGLVDLAPEAADAEGDALLAALAGERDQCALRGGALYGARLERRSAEPASAAPP
QPLRADATYLVSGGLGGVGWELLEAWAARGARHLVAIGRSAPSAAQRQRLAELARAGVEV
RVLAADVRDRDALAAAWAALAPALPPIAGVVHAAGVLDDAALLRHQPDQLRALLAPKLTG
ARNLLAIATSAAPGEGAAGAPAGAGGLDFFALLSSLAGVLGSPGQAGYAAANAALDALAA
AWRSRGVPALSVAFGPWQVGFAAAHQQALAARGVAAMPANLAVDALAACIARGPGDAVVT
AADLGAVAAHMPERSRGVLAAFAAAPDAAAGAPAGGRTAALAEALRKAPPRQRARVLLEG
LAAAVRGVLGRAAHVRIEPTQSLFELGLDSLSAVEFRTSLQRALGRSLPASLAFEHPTLE
GLSEALLAMLADELAADESDAETDAPAAAAAPPPRARAEDQPEDQPVDQALSALAAGSLD
LSALPPATLAALAARARSQRPELAVLGAEPIAIVGMGCRFPGGADSPEALWALLRDGVDA
ITEIPVERWDPDTWYDPDPEAADKTTIRHGGFLGDVAGFDAGFFRISPREARCMDPQHRL
LLEVAWQALEDAGQDPERLRGTSAGVFIGFMNNDYASIAELAELEGHLATGNGISNAVGR
LSFVLGVHGPSVALDTACSSSLVAIHSALESLRKRECDLALAGGVSLILSPGLTILMSKL
GGLAADGHCKTFDAAADGYVRSEGCGVLVLKRLVDAQRDRDRVVAVIRGSATNHGGRSGG
FSQPNARAQQALMREALARSQTLPQQVSYLEAHGTGTPLGDPIEFRAAAAAYGPGRGGDR
PLHIGSIKTNVGHTEAAAGVAGVMKVALSLRARQIPPHLNLRTLSPEIDLDAVPARIPIA
LTPWEPIAGRRIAGVSSFGMSGINAHVILEEAPPPAAAGASGAAEPAPARAELVALSAAS
EAALMALVRAYQAHLGEPGEGAPARPAAPTLLDIAGTAGARRAHHGHRLGLVARDLAELR
TGLAAALAGRGGGVVRGASEAGKRPRVVFVCPGQGSQWLGMGRALYADEPAFRAAIDRCE
RAIGEYVSWSLVERLHAAEAPAGIDVIQPMLFAISVALGAQWRAWGVEPDAIVGHSMGEV
AAAHLAGALSLDDAARVICRRSRLMLEVAGRGAMAVVELGAEALAPRLAPYGEALCVAAA
NSTRSSVVTGEADAVERLLAELEQARVFARRIKVDVASHGPQVDPLAQPLLAQLEGLRPG
LAEVPLWSAVSASPAEGPELSPDYWMRNLRQPVRFAETITALLASEHALFVELSAHPILA
PAIEHTAEDRGAAAWVVGSLERDKPERASMLSALAALYARGYPLDFRRLYPESAAVSLPT
YPFQRERYWVEPVKTTPLLLRHRADLRGAALAPAASAAGAGAGDEATRGLSYELSWEPVA
DPGAGEPGRRYALVGDRGGVAERLAAALRSAGHACAVVAAEAPDEAALAALADGRPLAGC
VYLAGLDGAAASDAEALPLAAAHAAGVARALAVLGRFGAPPLWLVTRGGQSVAGEAPSLS
QAALWGLGRTLAAEQPALRSALIDLAPAAAEPGGAGAQAAAGDEIAALTRWLSAPHGETQ
LALRDGRTLAARLGVAPEAAAAAAVTIRADRTYWIAGGLAGLGGAVAEELVRRGARHVLV
TGAREAAADEACRQRLAAAGASVSYAAAAHAEPEALAAALEALPAPLAAVIHAVPPAAPA
LPLAATEDAFAGAVRALADDAWRLHHAAGERELDFALFFGPAASLLGGVGQAAAAVAAEV
AAALAARWRRRSRPARALLLASWPGAEDPALAGLGIAPVAVETAVAAALAAAVAGGAPAR
MIAAIDWPLFRSAYAQRADERFLGQLGRAEDAAAEAAPLRERLRELAPERARALLAELVA
DETREQLGLAPEQPLPSRTPFTELGMDSVMSLKLTTRLGRALGVRLATVVIFEYPTVAAL
TEHLASEVLELPTSAPADAAPGYAPDPALAGADTDTDTDTDTDDDDDDLSEDELAALLTR
KLES
>E3J7L1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia inefficax (strain DSM 45817 / CECT 9037 / EuI1c)|TrEMBL
MKDCTTRDAAVEVDAQARPRRPAGRRDEVIGVSPLGEPDPRLVAAISGAGALGVLDLGAD
PANVAPALRRTARLARSPFGVRVSHLGAVDADELARHRADVDTVLLAGATLARGAARRIL
DALPDARVLAEVTSVGEAALAVAAGADGLLARGAEAGGRVGELSSFVLLQQLLADGGPRT
DDGAAVPVWCWGGIGVHTAVAAVTGGAVGVVLDVQLGLLPEATVTEATGATLRRMDGSET
VVASGYRVYQSPAARRAGEDVAAWSAAAVTAGLGARDPERQLLPVGQDAFLAAGFAARFG
TTARAVRAIRAALDAAAGPAVLAAADALLAGDSALCASWGTTRPIAQGPMTRVSDQAGFA
RGVADDGALPFLALALADAAQSRRLMAETRDLVGARPWGVGLLGFAPEELRAAQLEVVRE
IRPSCVIVAGGRPSQAADLERAGIPTFLHVPSPTLLRQFLDAGARRFVFEGSECGGHTGP
RASFPLWEAQLDVLLDHLARTAQGTTADGEEISAGDGLQVLFAGGVHDARSAAMVAALAS
PLAARGVGVGLLMGTAYLFTREAVEHGAIQEEFQRQAVAADQTALLQTAPGHVTRCLASP
FVDRFYAARDELRARGVPDEQAWETLEQLNVGRLRLASKGLERRGDKLTAVGPKRQRAEG
LFMAGQVAVLRSATTTVHQLHDSVTEDARGYLRDQPQRRRDGRPAAETTPLDIAVVGMAC
VLPGASDLATFWANVVAGRDAISPVPPERWDVGVYAEDGSGPTGEKSRSRWGGFLDRIPF
DPLRYGIPPSALASIEPVQALALETARRALEDARLAPDRVDHSRTGVVFGTEPNSDLSAA
ITLRALLPAYYGQVPAELDDVLPRITPETFTGILGNIVASRVSNRLDLGGPAYVVDAACA
SSLAALDLACKELRFGSADVMLCGGADLHNGVLDYLLFSSVGALSPTGRARPFAADADGT
TLGEGVACVVLKRLADAERDGDRVYAVIKGLGSASDGRSLGLTAPRPEGQQLALERAYRN
AGVSPAEVGLVEAHGTGTIVGDRTELTTLTRVFTEAGARHGGCALGSVKSQIGHTKTAAG
LAALVKASLALHHGVLPPTLHVQTPNPAWEPDVSPFVFAATARPWSRPAAERVAGVSAFG
FGGANYHAVLAGHAGAVDGRHALDRWPAELFVFRGATRAAALAAVAELRALLIANDAAGR
PWPLRDLAATTARRARPPRGPVQLAVVARDLDDLAHLLTRAADGDTDPRAGLFVVDGPPV
GGPPSDTGPNVAGGAGDVAVLFPGQGSQRPSMLAELFVAFPELREYLRLGERWQDALFPP
SIFGGGPASQDAEPADVPLRDTRVAQPVLGIAGLGMFHLLSRLGLAADMVAGHSYGELVA
LCAAGAFAPETLLELSRLRGEAIVAAITAPDPAAGGTTRPDQGAMAAVRATPSDVDRVLA
DPRVNGPVVIANHNAPDQIVISGPTTAVETAVRLLRDAGHSSVPLPVACAFHSPLIADAA
VAFAEALAATPLTRPRLPVWANRTAAPYAAADGAADPGDAVRDELAAQVTAPVRFVEQIE
AMYAAGARVFVEAGPGRVLTGLVDAILGDRPHRAVACDGRRGGLTGFLDAVAALLVAGVP
LGTGWLLDGRDAVDHASSVPMAPPRWSVDGRSICRADGEPLSGGLPSARRIRRTAAAPAG
NPDSVPTPRQGVSVTLRADQPVATGAAPAGWPSFDQVEGSRPADREALVSEFLRTSRDNL
AAQRDVLLSYLGAGRDQVAAPPAVTARQPAADVLLAEWNGAVDAEPLAGPPPAADVPTAG
AGGATAAPPAQVPVDVTAQVLDLIAESTGYPTDMIDADLDLETDLSVNSLKRTELAGLLV
DRFALADAGGVDELSRLRTVRGIVRWLGERVGGDQPRPTPPIEVSVPEVPAGTAEVPAGT
GVPAHGARGHSPKRFVLARRPSPLATSEVDLTGTSWAVIGRTVNVPGREAVLRRLTDLGA
EAHFQLVDELAQIEQSDLAGGIYLAAPPGSDSPDLPEAFGAVRAVLRGRPRWLLAVAPPD
AAPAAGLRGLFRTLGREYPDTLIKLVETDAQAGPALADLVTAELAEPPGGPVVVAHRDGA
RLTEELAATPAGPLATAGTGPAGDGAAEAAALGLDQDSVVVVVGGARGITAGFSVLLAGA
ARCHLELAGRTPDIGDDEDPRLAGALDRRALLGAVQALGETTPRDATRAVDRVLAQREIR
ATLGAAAARGGDARYHSLDVLDTEAVHHFVKQVFAQHGRIDAVVYAAGVIEDRLVADKDL
ESFRRVFDTKVAGARAMLAALGELPTPPRTLVFFGSIAGVLGSRGQSDYAAANDALETLG
ADWARRTGSRALTAHWGPWAPDESHPGMVSASLEWDFARRGVDLIDPEEGHHCLLRELAW
GPRDLRGVVYTASGW
>E0I4N0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Paenibacillus curdlanolyticus YK9|TrEMBL
MLKLDDLQLDDMFLSETPDIKEISGNEIAIIGMSARLPQAEGLDDFWSNLKESLDCVGEF
PAARRKDAGSLLRGIGIDDQSIAFGDGAYLSDVDKFDYRFFQLSPMEASLMNPAQRLFLE
TVWKTIEDAGYGGKKLKGSKTGVFLGHTSIPFAHSYYDYSRFIAEKDMSLVPMAIPGNLN
AMIASRISYLLDLKGPSLVIDTACSSSLVAVHMACQSIRNGECETAIAGGVKINLFPIDS
EHKLGIESSSDRARTFDDHADGTGRGEGVAAVLLKPLSHALKDGDQIYAVIKGSSINQDG
SSIGITAPNALTQEEVIDEAWHNAGIDPTTIAYIEAHGTGTKLGDPIEITGINRAFSRHT
DRKQFCAIGSVKSSIGHLDDAAGIVGMIKAVLALKNKAIPPTLHFTYPNRNIEFEQSAVY
VSNSLSDWEYEGFPRRSGVSAFGLSGTNCHVVLEEAPEREAVGAESGKPYLLTLSAKSRS
SIEQLVASYDDYVQSEAFSEVSLADMSSTMNTGRGHYNYRIAIVASNREEVRASFRALVQ
GGLQSYPELHVRFNETMASNEAIHSLSRKAADMVRSALDVNQLDGKLLDTLSELYTDGAD
IDFESLYFGDAIRKLSLPVYPFERSRCWIELNPRHVSAEQLDSQTQQQVALSGRVNGEYT
QTESAVAQIWGQTLGFNDIQVDANYYELGGDSVIASRIVNALNQQFGLQVDVTGLLRNPT
VEQLASHLDAMASAEGQGLSDELRIVPVEKRDYYDASLIQKQCYAQEQFSNIGTALNMPL
VMEFQSAADAGRIQRTLQALLDRHESLRTSFAFAEGDLVQFVHDNPALTWAERNVTQAEV
DEAIHAFIQPFDLGAGPLFRSMLLHVDGQRDVLIVDMHHIVSDGTSYQIFVQEFITLYEG
GTLPPLEVQNKDYCTWQKQFMQTERYEKQQAYWKHILFENVPTLQLPQDFKRGDGRGFEG
NTLKFELSDETVHRLTRAAQEANVTLNTLLFAAYTLLLQQFSGQQEIIVGTVVSGRNHKQ
IEGIIGAFLSLLPIKQTIIAEETIRQFLSSCNEAMLGAFENQDYHYTSMIELCNIKLDRS
RNPLFDTALIFHNEYDGKVSLEAGGIPFTVRSISHNRSQLDLKLDIYTSQSDALMCHLEY
KTDLFKQETVEDFIAKFHSLLSEFSSHADKRIDELQLLSEEEKLQVQQRLEQNVRGIGQS
IELAISASFTAEPIDRHVAWWASEFSLPLDLKFAAYNQVFMELLEPSSLLSTNKGANVLL
VRFEDWIRYNPSNQDAVLCEELERSYREFTSILVDKQKSVPYFVGVFPIATHLGLSEAVA
ACLERLSKQWQQLIEELDHVYPLDFTSIADLYQVHAIFDPVKDAEGHIPFTDEFMAAMGA
TIVRAIHSWKSPSFKVIVLDCDNTLWSGVCGEDGPMGVQVTDSFAALQRFMLQKREKGML
LALSSKNNEADVWEVFEHNPNMLLKKEHFIGWKINWEAKSANLRELAVDLNLGLDSFIFL
DDNVMECSEMMMNCPEVLTLNLPREEREISSYLRHVWAFDQLIVTDEDLKRSERYIQEKQ
RQEVQQEAHSPLDYLRGLELKMSMRAVEPSQIARVSQLTKRTNQFNLSTIRRSEDEIKQL
MDTSETACWSIEVADRFGDYGLVGVVIAIRQEQSLFIDTFLLSCRVLGRTVEDAVMTGLA
QYCAANGLTTLEAKFYPTNKNEPFLAFIERAGWEKSEETADYAAYRLPVDAIQADAQIID
CYYNAAYPVQDAASSVKQEMLQAVSQIAAASAVAEPDGSAEWTVPTWDVHQINDEALLHA
KHLTPIRYHSAYLIMDKQREEQLTSSAATDEYYEAPRTEAEKRIAEVWQNTLGIDRISVY
SKFFDIGGTSLSGIQIVSTLSMEFELSLNDFFEYDTIASLAKNVPFKPNYLLELLKEKEE
LAKIELKANIEEDPAIKAQLDQYEEELSACREMDLTDVVVYKDILLTGATGYLGIHLLHD
LLTTTTSNVHMIVRGADAAEAEARLQAKLAFYFSEDLASRYADRIFVYNGDVAEERLGLS
EEQYAMLADVIDCIINSAANVTHYGRYQDSHRVNVLGTERLVDLAFAGQRKVLHHISTPL
VAFGKIDGVDDVLYTENEHDLGQDDDNIYFLTKLESERVIVAARERGLACSIFRVGNLNY
NTETMKFQENIEGSALYSMIKSFINIKMVPSLSGRGLDFSFVNHVTQAILLLFNKKQLQN
KTHHLYNSNRINGLQLGEYIQQSGYTDVELRTVGEIFGSYHIKELQEDIMNIVIHGGLMG
NLRDTNFHMRADRTNLLLERLGFTWKPVDQTNVQSMLRYAEQVGFL
>A0A086K1A2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii GAB2-2007-GAL-DOM2|TrEMBL
MASDLTQALLSCLEAVTEPDSEDTPNQRTDAEYRFCAVRQDDITFAEFLNRVSVQFEVPI
GPLAAKDYESFSSFVFHICELKKEKQVNVKTSSHHIIHRTNRYSTENEKASISIVGIACR
LPGNAKNPGDFWTVLVEGIDAIVPIPSKRWNHKEFSEGHSERGTIYVKEGGFIDGIEKFD
NGFFKISSSEARRMDPQQRMLLELSHEAFESAGLQAITDDNHKFGVFVGCSSSEWTILKT
KQTERLCAFQTANTPHALLANRLSYTFNACGPSLTIDSASSSALVAVSVAASHMEMGQCD
ACLVGSSSLMLVPEATVALCAAGMLALDSRCRPFDAAANGYGRGEGAVVFLLERQMYSPE
SRCKQKSLATIRGHGTNHNGRSVSVTAPSDVAQKKLLEGVLRTASVEPQQVAYLEAHGTG
TKLGDTIEFRAIKSVFSTSRSVDNPLLIGSGKSNVGHLEGCAGAVGLLKALLVLYFREVP
PTLHFKKISPLIDDEGFDYQIPTKRLTLAGDRPILAGVSSFGLGGCNAHVIIESVPKDRE
MDALSLSRRHIWDHMEFPVFESADDGNSFGGLAMRHNVDLCNSTCNHLRRRSTSSLIGDG
TPGLRVQQYGTTEGSSKANEPHAITEKQISRWTRDNRKGLYVEVESMKDELERSFSLEDD
NGSVTGSVQTEQTEPDQMANEVVNTVDEEAVQTLVLQTVRQILKEAVSIHRDVSLKTLGI
DSLAAVEFRDSLQESLGISLPASLIFDFPTIDDVCRFLAQKLQSGDGGERRNTPTNLAQP
RPSTSSETCVAVRGMSCRFPGAEDGTTESFWEMLHSDSDCIQEIPTSRFDAASIFDTDYD
ARDKIYVKAAGILRGADMFDNTFFKISEVEVRHLDPRQRILLEVAYDALVDSQVLGDQGL
AAIDNEIVGVVIGCSGNDWNTFLQQHALSASSFSGPGTSPALLSNRVSYSLSLRGPSLTV
DTACSSSLVAIDIARQLLNASQCNLALVGGVQLLLTADTFIHYCRARMLSPDCRCKTFDA
SANGYVRSEGCGVVLLENTHDRQVSKNTTYAWLLGSANNHVGKSASLTAPNGPAQQAVIL
ASLRSAHLQLTSQIHLIETHGTGTSLGDPIEIGALQAVYGQGT
>A0A7Z7IM57|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium simulans|TrEMBL
MEVSLEKVTQAFRKTLIENESLKQLLAASLEPIAVVGMACRLPGGVDSPQALWELVHTGT
DAIGGFPTDRGWDLAGLFDPDPDAVGKTYTRSGGFLADVAGFDAEFFGISAREATAMDPQ
QRLLLEVCWEALETAGIDPTTLDGTDTGVFAGAWSQSGGGGPDGAEGYGLTGAATSVASG
RVAYVLGLQGPAITIDTACSSSLVATHLACQSLRNGESSLALAGGVTVISSPALFIEFAR
QRGLAPDGRCKAFAAAADGTGWGEGAAVVVLERLSDAQRHQHPVLAVIAGSAINQDGASN
GLTAPNGPAQQRVITQAAANAGIALDQVDVVEAHGTGTTLGDPIEAGALLATYGANRDPE
HPLWLGSVKSNIGHTQAAAGAAGLIKMITALNHAVLPPTLHVDQPSPHIDWSAGAVQLLT
QARPWPASDHPRTAAVSSFGISGTNAHLIVQQAPTRAPTTAAAAGEPPLRIWPLSARTPA
ALHAAGARLHQHLLDHPDLDLTDLAYSLATNQPHPHLASHHYRAHQPSKTVFVFPGQGAQ
YPAMATQLYTHHRGFADALDECDRALHQWIGWSVRDVLNQHPSAPRLDRVDVVQPVLFAI
MVSLAELLRAHGITPDAVVGHSQGEIAAAYVAGALPLDQAAKIVALRSTALTRLPGTGTM
ASVLLHREQLEPRLEQWDTRLHIAATNGPTHTIISGDTAAMVQFTTVCERDGIHIRPIAV
DYASHSPQVEELRQHLLRELAELTPQASRIPLYSTVQSALSSHPLDTTTMNADYWYRNLR
EPVEFHDSITELLAQGERIFVELSPHPVLAPALSDTLAHHAEHTQSTVITALHRDHPDLD
TIAATLAHLHTHGHSPSWTTLYPDAHTVGLPTYPFQHHPYWLPSEVYKGQPPRAPPTHRC
GCQRRRARQARPSPVGRGDRARRSRPDRVDRTVIDHHARLARRP
>A0A655CFN0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MLGHSGTEIDAHKAFQDLGFDSLTAVELRNRLKTATGLTLPPTLIFDYPTAAELAEHLDI
QLANAPAVTVDQPNPSTRFNEVTRELQALLDQPNWNPDDKTRLIKRLQAILTDCTAPPAS
SGPSTTHDDEDITTATESQLFAILDDELGP
>A0A2K8RKF4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MACDVADRAALVELLAAIPAHRPLTAVIHAAGVLDDGTVRSLTAERLNAVLRPKVEGTRN
LHELTEHLGWPRSCCSPP
>A0A445NHJ1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces netropsis|TrEMBL
MQEDQQDKVVDYLRRVAADLRRARQRIDELESKSREPIAIVGMGCRFPGGVSSPEGLWDL
VSSEGDAISGFPADRGWDLAALTGDGEGHSDTHEGGFLYEAGDFDAGFFGISPREALGMD
PQQRLLLEVSWEALERAGIDPLSLRGSQAGVFVGSYHWNPGTARATGELDGHALTGTAAS
VLSGRLAYTLGLEGPALTVDTACSSSLVALHVAMRSLRDDECSLAVVGGVTVLSDPAVFV
EFSKQGGLAPDGRCKAFSDAADGTGWSEGVGALVVERLSDARRNGHPVLAVLRGSAVNQD
GASNGLTAPNGPSQQRVIRQALANAGLSVADVDAVEAHGTGTRLGDPIEAQALLATYGQG
REVPLRLGSLKSNIGHTQAAAGVAGVIKMVMAMRHGVLPKSLHSDTASSHVDWSAGAVEL
LTESVAWPAGERPRRCAVSSFGVSGTNAHAVLEEAPRDAEPAAEEPPATDNPATVVPWVL
SGRAPAAVRDQAANLLSRLDAEPGLRPVDVGYSLASRSLFEHRAVMVGAGMDDLREGLGA
LAAEETAAAVVQGVADIDGKTVFVFPGQGSQWVGMGARLLEESPVFAERLAECAQALGAF
VDWSLTDVLRQMPGAPSLERVDVIQPASFAVMVSLAALWQAHGVSPDAVVGHSQGEIAAA
VVSGALSLEDGARVVALRSQAIGRRLAGRGGMMSVGLPVAEVEGRLGGFAGRVSVAAVNG
PRSVVVSGDPEGLDELFAQLTDDDIRVRRIAVDYASHSAQVEDLHEELLSELGPIRPRES
DVPFVSTVSGEWLDTSGMDAEYWYGNLRNTVRFEAGIRTLLDADHGVFVEVSSHPVLAMA
VQDVIEDAGGHAVAVGTLRRYEGDLHRFLTSLAEVYVRGVPVDWRSLYTGTGARRVDLPT
YPFQHERLWAMPHEVELLAAADPADTEFWAAVEREDLGSLTSRLHIDEDSLAAVLPALSS
WRRERREQSALDAWRYRVAWSPLSGVPKASLSGTWLVVTAEGIADDDVVTALTGQDAAVR
RLVLDDSCIDRAVLAARLDDAHDVAGIVSVLAAAEQPSTAYPQLASGLALTVSLVQALGD
TGIDAPLWCLTRGAVSTGRSDLVTHPVQAQVHGVGWTAALEHPQRWGGLVDLPDTLDERA
GRRLAAVLAGTTGEDQLAIRSSGVFTRRVVRAAAGGQGAGRGWRPHGTTLITGGSGALAP
DLARWLAAQGAEHLVLVSRRGPAAPGATELIAELAELGTEAEAVACDISDRDAVAGLLSG
LGADGRAVRTVVHAAAVIELESLAETTMEEFARVVHAKVAGARHLDELLDDEELDAFVLF
SSITGMWGSGRHAAYGAGNAYLSALADHRRARGATATSLHWGKWPDDAEAAQLDPHQIRR
SGLGFIDAGPALAGMRRALDDDETVLAIADVNWDVYHPIFTSGRPTTLFDEVPEVQRLTR
PVAAAVNAGAEGEFAARLRALPAAERDRLLLDLVRGQAATVLGHASGEAFPERRAFRDVG
FDSVTSVDLRNRLVTATGLRLPSTLVFDYPTPLALAEFLRDEIAGTAAATAPAVSAAATD
EPIAIVGMSCRYPGGAHTPEDLWRLLVDGADVISEFPADRGWDADALFDPDPDRHGRTYS
VQGGFLHEAAEFDASFFGISPREAVAMDPQQRLLLETAHEALERAGIDPDSLRGSPTGTF
IGATYQDYTSGVPNAAESETYMATGTASSVLSGRVSYLFGLEGPAVTVDTACSSSLVALH
LACQSLRNGESTLALAGGVAVMSTPSPFIGFSRQRALAVNGHCKPFSDDADGMTLAEGVG
LVLLERLSDARRNGHRVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRQALANAGVSPAD
VDVVEAHGTGTKLGDPIEAQALLATYGQDRETPLRLGSLKANIGHTQAAAGVASVIKMVM
ALREGVLPRTVNVSEPSSRVDWSSGAVELLTETEKWQAEGRTRRAGVSSFGISGTNAHLI
LEQAPDTEADGAEPAPDHTGVVPWLVSAKSDAALRDQAARLLAHVGDSPELPPVSVGWSL
ATTRPRLEHRAVLLGETHEDFTRCLEALATAGTTPGVVRGVAATGDAGPVFVFPGQGSQW
WGMGRELLETSEVFRSAVDDCAEALAPHIDWSLRDVLAGTGDPALLERVDVVQPALFSMM
VALSALWRSHGVEPAAVMGHSQGEIAAACVAGALSLPDAAAVVALRSKALLALSGRGGMM
SVAASVEQVTALLGPWGDRLSLAAVNGPSSVVVSGDPEALAELKEQCATEKIRARMVAVD
YASHGSQVELIQDELADLLASVTPRAPKVPFYSTVTGERLDTPAMDGTYWYTNLRQTVQL
ERATRALLADGHRLFVETSPHPVLAGAVQETAESAEIESAVALGSLRRDEGDTKRFLTSL
AEAHVQGAPVDWRAVFPASPSQAPVELPTYAFQRRRYWPEAELPAPGGPGTGTEADTAFW
GLVENGDLDTLAGELGVAENDGRSSLGALLPALSAWRTKSRQASAANALRYKVDWTRLRE
PGGTTPAGTWLVVAPARGADDPWATAVIDALGPDTVRVDVEDTDRDVLTALLAATAEGTP
GLTGVVSLLGLAEERHPGFTSVPDGLAMTLALVQALGDAGIGAPLWCLTRDAVAVGRDDK
VTHPVQGALWGLGLVTALEQPGRWGGLIDLPDTVDPRTAARLRAVLAAPDGEDQLALRAS
GSFGRRLVHAAPGGNRPERRWWERGTVLITGGTGGLGGRVARWITERGARHVVLTSRRGP
EAPGAEALRAELEGLGAQVTIAACDAADRVALHALLAGLPAELPLTAVVHAAGVADGDAD
AQSLTLEQLDALLRSKLTAALHLHEATSDLDLDAFVLFSSGAGIWGSGGQAGYAAANAFL
DTLAEHRRARGLTATAVSWGAWAEAGMATVAEVHDRLSRRGVMSMEPSLAIAALQQSLTD
DDTQVTVTDMDWELFTPSFTATRPSPLLSGIPEVRAVLSAQEAPAGDDGGDESALRRRLE
SLSDAERGRALLDVVRVEASATLGHEAADAIPADRAFRDVGFDSVTAIELRNRLRVATGL
ALPAALVFDYPTPTALAQCLRSYLFPDTAPAQKTDDPDAHIREALTTVPISRLRKAGLLD
MVLQLANEEAETATAAPDAASPIESIDDMDAESLLRLATESTTN
>A0A5B7V357|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MANEEKYLDYLKRATADLRDARRRVRELEDARQEPIAIVGMSCRYPGGVNTPEDLWRLVA
DGTDAISAFPTDRGWDTDDLFDPDPDKQGTSYTAEGGFLYDAPQFDASFFGVSPREALAM
DPQQRLLLETAWEAIERAGIDPVSLRRSRTGVFAGVMYYDYATRLHALPEGVEGYIGTGN
AGSVVSGRVAYTLGLEGPAVTVDTACSSSLVALHLAAQALRQGECTLALAGGVTVMPTAG
TFIDFSRQRGLSTDGRCKSFAASADGTGWGEGAGLLLLERLSDARRNGHKVLAVVKGSAV
NQDGASSGLTAPNGPSQQRVIRDALASAGLKPGDVDAVEAHGTGTTLGDPIEAQAVIATY
GKEHSADRPLWLGSLKSNIGHTQAAAGVAGVIKMVMAMREGVLPQTLHVNEPTPQVDWSA
GTVELLTEARAWAERDGGGPRRAGVSSFGVSGTNAHVIVEQVREPEEPGTADDGQDAAPS
VVPGVIPLALSGRTPEALRAQAARLHAHLLADTGIEPAAAAWSLAVARSRFEHRGVVLGR
DRDDLLAGLERLADGDALTGRALGGMVRPVFVFPGQGSQWAGMARELLDESPVFAERMRE
CADALAEFVDWDLLEELGGDRFDRVDVVQPVLFAVMVSLAAVWQAAGVKPAAVVGHSQGE
IAAACVAGALSLRDAARVVALRSLAIRELSGKGGMVSVPLPESEVREVIAGWAGRIEVAA
VNGPAQVVVSGEPEALEELVAQCVGQDIRARTIPVDYASHSSYVEQIEAQILEALEGVSP
QAAEVPVYSTLTGSWLDATPMDGGYWYRNLRQTVLFEHATRGLLAEGHGLFLEMSPHPVL
TVPVQATIDATDSQAATLGSLRRDDGGADRLAASLAEAHVHGAELDWKSLFPGTRTTVDL
PTYPFQRDHYWMLAPDQDADGDAALAVDEVEARFWEAVEREDLAQLTSTLVDVDESSLSA
VLPGLASWRRQRRERSTIDGWRYAVTWKPQAGGLPVPALPGRWLVVVPESAGEDTWTPGV
VEALAQAGAEVEELRVAAQELTREALAVRLREVAGAEFAGVVSLLGFEESVHAEHAGVPA
GLAGTVALVQALGDAGIAARLWAVTRGAVSTGRSDRVESPVQAQLWGLGRVVALEHPDRW
GGLIDLPPSYDARGASRFASILTGLGDEDQLAVRDTGVFVRRFAHAPLDGPAVEWAPRGT
ALITGGTGAIGGHVARWLAREGVEHLVLTSRRGLDAPGAVELQAELEELGAEVTVAACDV
ADREAVVRLLDDLAAEGHTVRSVFHAAGVSPSYPLADMSAADIAEVFGAKTAGAAHLDEL
LDSEGLDAFVLFSSNSGVWGGGGQGAYAAANAYLDALAASRRARGLPATSVAWGAWGGSG
MAAEEQAEEHLRRRGVTAMAPERAVAALAQAVAHGETFLAVADVDWERFAPAFTSVRPSP
FIGDLPEVRRALAEPETAAPAGAKGAGSEWAERLAGLAEREQERQLLDLVRGHAAAVLGY
AGPEAVEPGRAFRELGFDSLTAVEVRNRIATATGLKLPTTLVFDYPTSAVLAGYLRTQLV
GEPETAPVVARRVADVDDDPIAIVSMSCRYPGGATSPEALWRLVAEGTDAISVFPTDRGW
GADGLFQPEQSGSDDTSFAAQGGFLYDVSEFDAGLFGISPREALAMDPQQRLLLETSWEL
FERAGIAPSALHGSSTGVFVGACSQGWSAGLAHAPEGVEGYLMTGDATSVISGRLSYSFG
LEGPAVTVDTACSSSLVALHLAAQALRQGECDMALAGGVTVMVSPAAFLEFSRQRGLAGD
GRCKPFAEAADGTGWGEGVGLLLLERLSDARRNGHDVLGVLRGSAINQDGASNGLTAPNG
PSQQRVIRAALANAGLTAAEVDAVEAHGTGTTLGDPIEAQALLATYGQDRPAGQPLWLGS
IKSNIGHTQSAAGVAGVIKMVMAMREGVLPQSLHVDRPSTHVDWAAGAVELLAESRAWSN
RHDGGPRRAGVSSFGVSGTNAHVIVEASPVAEPAEPVEPASPVTTAVPWLVSGRSAEALR
AQADRLREHVVTHTGLDPVAVGRSLLSGRSALEHRAVVLGRDSDELLVGLEALASGGPGV
VSGSVTEGRLGVLFTGQGSQRIGMGRELYEAFPVFADALDEVCAHVDPWIERSLQSVMFG
ADAELLEQTGYAQPALFAVEVALFRLAESFGVRPEIVGGHSIGELAAAYVAGLWSLEDAA
QLVAARGRLMQALPEGGAMLAVQATEADVLPLLSDRVGVAAVNGPAQLVLSGERAALEGL
EQTLREQGRKVKWLKVSHAFHSPLMDPVLDDFRRVAQQLTYQDPTLPVVSNLTGEPAEPA
ELKDPEYWVRHVREAVRFHDGLKALAGQGVATLLELGPDAVLTAMAHDTLTEPTAQAGLV
AAVRKDRAEPGTFLTALAQLHVRGVEVDWTPLYAGAEARGRVELPTYAFQRRRYWPSAAT
GAGGDVSATGLVAAGHPLLGAAVPLADSDGHLFTGRLSLATHPWLADHAVAGRVLLPGTA
FVELAVRAGDEVGCGVLEELTLAAPLVLPERGAVQLQVSVGAEDADGRRAVALHSREERE
DHAADGGWTAHATGVLADGDLRQPEFRLAEWPPRDAAEVDVEGLYQHLTELGFSYGEAFQ
GLRAAWRRGDEVFAEVALPQEQADSAQAFRLHPALLDAALHVLGLGVLRDTGADGEGARL
PFAWSGVSLHATGASTLRVRLAPAGGDGVSLAVADGLGDPVATVDSLVFRPVAVDRLGGG
VADDSMFHVEWRPQSLAAAEGVAPVSYEELAASAELPDAVVWRAGGAEGAPSPEAVSARL
AEALGVVQDWLADERFAALPLVVVTCGAVATGDSAVDPVGAAVWGLVRSARSEHPGRFVL
VDTDTDTGAGLSSGSGSRSGSGSVPGVDESVLAAVLASGEPEVAVRDGAVFVPRLSRVPA
TGGADAPWGAGSVLVTGAFGGLGREVVRHLAAHHGVRDLLLVSRRGAEATGAAELLDELA
GFDAAVTVAACDVADRDALAALLDDKGTDLTAVVHVAGVLDDGVVTSLTPERVDTVLRAK
VNAALNLHELTAGRDLSAFVLFSSAAGVLGGAGQANYAAANSFLDALAASRRAQGLPATS
LAWGMWAQASAMTGGLADADLQRMTRGGVAPLSTQEGLALLDAAVGAADAPAALVPLRLD
PASLRAAADTDADGVPALLRGLVRTPARRAAAGAATAEPAGQAPLIARLTGLDAAGRDKV
LTELVCTHVAAVLGYESAAAVEAHRAFRELGFDSLTAVELRNAVNGATGLRLPATLIFDY
PTPAALAAHLATALPLGGAADGGGLSVLDELDRLESALLAMEADSIAQSKITIRLQTLLS
RWSAPQSQTARPAGPADEDDLDLDAVSDEELFDALDDELGLT
>U7QAG4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Lyngbya aestuarii BL J|TrEMBL
MDLEENQVFAQINPSETIAEELNHYQIHPILLDACFQAVGAAFSEEQLDTYLPVSFQQLI
IHNKLDEKPFWSQVKLHFTSNPKVYSADILIANSEGEITAQINQLQIQAVNREAVLGNST
TNLQDWLYTVEWKPQPLSSSATNFVVQTQAIFDEIVPEFRQFLSQPQFKKYAELLPQLED
VSLSYIIQAFTQMGFEFTAKQQFLSQELADKLGITSKQQRLFERLLEILSEAGILQRKNQ
AWEVIQESIKIDSPSQIKTQLCLDLEIEAELSLLSACGSHLAEVLQGKLDPIQLLFPSGD
VSFLTQLYQNSPGAKVMNTLVEKVIQKALENQPQTQKLKVLEIGAGTGGTTAYILPHLKT
>A0A1N0TKF5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus subsp. abscessus|TrEMBL
MLDGLIAQRRAQGLPATGINFGPWGQGGMASSEAATANISAQGLIPLDPSAALAALAEVI
ANGTGQATILKANWQRAAKVLGSSRPPILDLVLPSAVGEVTGDSELLKQLMEIPVPQRAG
FVTEFLQREVQNFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFD
YPTIGGLAEYLVGQLPDADAESAEAPPAVESAEAESGTGPAAASDAVSELKE
>A0A7R8NR26|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. KY75|TrEMBL
MTSEPRSEVNGPHRGRSEPIAVVGLSCRLPEASGPAAFWELLSEGRDALTDMPADRWESI
SGDPVDGIRRGGFIDGIADFDASFFGISPREAVVMDPQQRLLLELTWEALEDAGIVASTL
ESSATSVYVGTAREDYTSLVYRQGSSAITQHTVTGTHRGIIANRVSYALGLNGPSLTVDT
SQSSSLVAVHLACESLRTGESDMALAAGVNLNILGEGIGGAEQFGGLSPDGRSFTFDARA
NGYVRGEGAGVLVLKPLSRALADGDRVHSLILGSAVNNDGATPGLTVPSAAAQERVIRLA
RERAGVEPDAIQYVELHGTGTPLGDPIEAAALGAALGTLKADGDPLRVGSVKTNIGHLEG
AAGIVGLIKTVLSIRHRMLPPSLNFETPNPGIPLGELNLAVNERLSPWPRPDRPLTAGVS
SFGMGGSNCHVILTEAPTRPTDPADPAASPARPSAALPVVVSGRTPKALDAQAARLAAQV
AADEDVTPAAVGRSSVSTRSLFAHRGVVLAADREELLAGLGALAGRLPAAGVVSGSEVGG
RLGMVFTGQGAQRVGMGSELYAAFPAFAAAFDAVCEHLDPLLERPLREVIASGEGLDLTG
STQPALFAVEVALFRLYESWGVRPDFLAGHSIGEVAAAHVAGVLTLADACVLVAARGRLM
QALPEGGAMVAVQASEAEVLDALSGHEAEVSPAAGSQAAVSLAAVNGPAAVVLSGDEAAV
LEVAGGLRERGHKTKRLTVSHAFHSAHMDGMLDAFREALAPLSFHPPRIPVVSTVTGEVA
ADGLLESPEYWVEQVRAPVRFLEAVRTLEAEGVRTVVELGPDGVCSAMVAESVLDRDTVH
AEPALRAGRPEDRTAGAALARAFVRGAEVDWDAVFAGTGAHRVELPTYAFQRERYWVTDL
PAPAAGSSPAVGATTAAPAAVTARPTGPTAGDRSAADLVTAHVAAVLGYGPDRSVESDLP
FRDLGFSSLMTVELRTGLAEATGLRLPSGLLFDHPTPAALAEFIGAELQGSGGAQEEEPL
LATGSDEPIAIVGMACRYPGGVASPEDLWRLVNEHGDAITPFPTDRGWDEDLYDPDHERS
GKSYLGEGGFLHDAGRFEPGFFGISPREAQAMDPQQRLLLETAWESLEHAGLVPRTLRGT
RTGVFVGATTGDYGPRMQDAPESAEGHLLTGTTPSVMSGRIAYQFGFTGPAVTVDTACSS
SLVAVHMAVQSLRRGESGLALAGGATVMSSPGMFVEFSRQQGLSPDGRCKSFAAGADGTV
WSEGVGLLVLERLSEARRNGHRVLGLVRGSAVNQDGASNGLSAPNGLSQQRVIRQAVADA
GLTVADVDVVEAHGTGTSLGDPIEAEAILATYGSDREGREPVLLGSLKSNIGHAQAAAGV
GGLIKMVEAMRHGVVPATLHVDEPTPHVDWSSGTVALVREHRPWPRTGAPRRAGISSFGI
SGTNAHVVVEQPDRADAPPPVKTRPVETAATDTSAAVDAARAPWLLSAPDADGLKAQAAR
LREFVTARPELRPEDVGLSLAATRTLFAHRAVVLGTAGDTGSGSGSGSGSGSGSGSGSGS
GSGSGSGSGSGSGSEGRLAALDALAEGAASPQVVRGSAAEPGRTAFLFTGQGAQRAGMGR
ELHAEFPVFAEAFDAVCAAIDPHLDRPLRELVFADEDDPDAALLHRTRYTQPALFAVEVA
LFRLVEHQGLAPDLLAGHSVGELAAAHVAGVLSLDDAAALVAARGRLMEEARSDGAMLAI
QAGPDEVVATFGADADAVSLAAVNGPRSVVVAGDEAVVERIETEWRERGHRVRRLRVSHA
FHSPHMDGILEEFRTVARSLTFHAPAIPVVSTVTGAPADPELLRSPDYWVDQIRATVRFH
DTVRSLYDEGATLFVELGPDAVLTAMARESLTDAGAEAATTCVALARAGRPEADTYTAAL
ATVQAAGAAFDLAARYPGAERIGLPTYAFRGAHYWLAPGARTDVPGLGLDASGHPLLGAS
VEVAGGDGETVLTGLLSLRAHPWLADHVVAGSTLLPATAFLELAFAAGEPTGADTVDDLT
LEAPLALTGRDSVRVQIKVAAPDADGARPFTIHSRPVSASGQPWTRHATGFLSAAQAPSP
DADQGTWPPAGAVALPTEDVYRELDGLGYAYGPAFQGVRAVWRLGDELLAEIALPEGQQE
HAGRYGVHPALFDAALHPLLPGAAEGGSAAKIRLPFAWDGVRLHAAGAASARVRITPAGP
DTVSLAVTDRAGEPVVTVASLTLRPVARAAFAEAAVVREPLYVLDWPVVAAGEVPEWTRT
ELTGPAGLTGLSAQDPAAVEPADLVVLTLTEIPDATLTETPGAVPGTARTTTAQVAAFLR
EWLEAERFERSRLVLVTTGAVAAAPGEDVTDLVHAPLWGLVRSAQTEHPGRIVLVDLDGH
GDADALVAGAVATGEPQIAVRDGEFRAPRLARAAARTAPPVRFAAEGTVLISGGTGGLGA
VLARHLVTEHGVRRLLLLSRRGPDSPGADTLRTELTELGAHVDLVAADAADREALARALA
TIPEEHPLTAVVHTAGVIDDATIASLTPEQLDSVLRPKIDGAWNLHELTRDHDLTAFVLY
SSIAGTLGTPGQANYAAANTFLDALAHHRHAHGLPAHSLAWGLWDASTGMGATLSGADVA
RWTRTGVLPLSEEQGLRMFDTALGTDAPLTVAAALDPARIAGSGLPPAVWRGLVRTRRTA
RTAAAADASEWAARTAALPEDERGPAVLQLVRDCVAAALGHTSGEQVDVTKAFKEQGFDS
LTAVELRNQLGTATGLRLPSTVVFDHPNPTALTAYILGLVPGQDQAGAAPGKAAKARRGK
RSGTADEPLAIVGMACRYPGGVRSPEDLWNLVTSGTDAISGFPTNRGWDLERLYDQDPEH
TGTSYVREGGFLHDADLFDRDFFGISPREATAMDPQQRLLLETAWETFESAAIDATALRG
TNTSVFVGSMYDDYASRLASVPAEFEGFLLVGNTSSVISGRLAYTFGLEGPAVTVDTACS
SSLVALHLAAQALRSGETDLALAGGVTVMAGPGSFVEFSRQRALSTDGRCRSFAADASGT
AWSEGVGLLLVERLSDARRNGHQVLAVLRGSAVNQDGASNGLTAPNGPAQERVIRQALVD
AGLTPADVDAVEAHGTGTTLGDPIEAQALLATYGAEREPGNPLLLGSLKSNIGHAQAAAG
VGGIIKMVHALNHAHLPPTLHAENPTSHIDWDTGTLELLTQGREWPATDRPRRAAVSSFG
ISGTNAHVILEQAPAVEETAGKDADGPRPETEAGTTVPWLLSAKSPDALRAQADRLRQFV
TANPELPTSDLGFSLATGRIRHEHRAAVVGADREELLRGLAALAAGEDATGVVRDEGGRR
GRTAFLFTGQGSQRSGMGSELYAAFPVFAAAFDEVDAHFELPLKDVVFGGGDELNRTALA
QPALFALEVALFRLVESWGITPDLLMGHSIGEFAAAHVAGVLSLADACALVAARGRLMDA
LPGGGAMLAVEAAEDETDLPDGVSLAAVNGPRSVVVSGDEEAVAALEARWRSEGRKVKRL
TVSHAFHSHLMDGMLDAFARVAEGVTFHPPKVPIVSTVTGSLIGDADLCTPDYWVAQIRQ
AVRFADGVRALEAEEVTEYLELGPDGVLSALVERCLTAPAGSVAALLRSGRPEPRTVVSA
LALSALRGARTDWSAVLPGARRTPLPSYAFQRQRYWLTAGDTKGEAADFGLDSAGHPLLG
AVVEVAGGELVVLTGRVSLRTHPYLADHAVMDRVLLPGTAFVDLALTAARRVGLALLDEL
TLTAPLVLGTDDEAQLQLTVGAPDDSGRRPVSVHSRRTGTGSGSGTGGDEPWTQHAEGVL
APGGPASPADGDTRAPAGVLEIDLTGVYDRLAGQDYRYGPAFQNLRRLSRLGDDLYAEVA
SAGEHPAGGAGFTLHPALLDAVLHALLPGVAGVADRPMVPFSWSGVSVPAAPVDALRARL
TLRKSDDTAVAVGLTLTDGAGLPVATVDELLLRPLSPDDLPVAGDRAAEGLFGLSWEPVP
LDRTAADEDRVVLGGTLDLPGARTHADLPALRRAVDDGEAAPSAVLLPLEAPAGTGDLAE
RARAALAGVLATVREWLADERFADTRLAVVTRGAVAPDGEDATDLVLAGVWGLLRSAQAE
QPGRIVLVDTDGNPLSRDALAAALRTDETQLMLRAGEAFVPRLTPAEPPARGVAGPDWGR
GTVLITGGTGALGAILARHLVTEHGVRRLLLLSRRGPDSPGADTLRTELTELGAHVDLVA
ADAADREALSRALATIPEEHPLSAVVHTAGTTDDATVMSLTPEQLAGVLRPKIDGAWNLH
ELTQDHDLTAFVLYSSIAGTLGTPGQANYAAANTFLDALAHHRHAHGLPAHSLAWGLWSD
TSALSSHLSDADVQRLARLGLKPLSAAEGTALLDAALRLDRPVHALTRIDRAALRTAQQL
PAVLRRLAPAAAAPVRSQAPLTERLAQLPPAEQEALVADLVRAKTAAVLGHADQSAVAAT
RAFNELGFDSLTAIELRNQLGTATGLRLPSTVVFDHPNPTALAAYILAELAPAAGPATPS
AATAVLADLDRLLGALPGALSDADAQGRIATRLRELLDLADPVAGTDEDLDGATDQELFD
LIDELD
>F8LUI1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptococcus thermophilus JIM 8232|TrEMBL
MYEPIAIIGYGVLYPPNSDNVQNFWKNIKNGVQGIREVTNEVWNVNDYYNEDENVPDKTY
CKNSAYLDNTGSLMDYISKFNLDDGKILSLNRTKKMVLYTILQAIDEANLNINELRDSSL
IIGNMLGDLDISDYMLYKFGKNYLNEVEKSSLVQRGSLEKITDKFGSRLYEELDLEDRNI
DGMFPSSLVTDITDFLGINQLSFVVDGACSGSLIAIDEAIKLLHNKVSKFAIVTGALGNM
GVTGNVAFSKIGGLSHSKSKPLDKENDGLTPGEGAGTIIIKRISEAIIDNNKILGIISGS
GVSSDGSGQSIYAPSTSGQYLAMKKSLNRANLTINDIDYVEMHATGTPVGDDVELESIVK
LCVEENLKHKIKIGSLKSQIGHSFSAAGMANLIKVLKGMENNQYPPTYNFTELSDKSKNI
VKDYLEVNVKNTPWERRNSGPRRALINAFGFGGINGNILVEEYLPSFHNKQAFDFHSNNG
NSDFSIVGIGVFDENKKTLKDILNKTEHDQPFQFPFIKYKIPPKILNKIDYAQQISLIAA
TEAIGNKLDGSDKSRVGVYVGSTMGLTNAYHSDIRIRSVEYTKILKDILDKENITISNSE
LNEIESNFKGKFESIEEDSLPGFMDNIVASRVSNYHNIQGTNAVYDHGMDSFSVALNQGI
LSLQNGENDIIIVGAVNGNVMDEYVEVFRNYSKSLSFETEIKSGACFYVVKRSEDVNEDD
TVLGTFSKSANTKFSIKAKSYDYLGASEAFELLNRLQNNCEKLFDEKVDTEESKLLKLNL
TYQLLKTIDVNSMSCDNPVGLTFEESDLSIIYNDVEDLKKKLKLAKKVLLNE
>B2IYN1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MRHLSLGSNTVPPTPPTLKSLTNNGFAVILVPFLQRIRRVHQVILQNQVGGLELSNNFNE
KAIAIIGMSGRFPKANNLDEYWQNLKNGVECISFLSDEELAAEGVDASTLNDPKYVKAIP
MIDNVEYFDAGFFSYSPREAKLIDPQHRVFLECAWEALEDAGCDPENYEHPIGFYAGASI
NTYILDCILGDRLRPKLDFESFLETFVGSDKDFLTSRVSYRLNLRGPSVTVQTACSTSLV
AVHLACQGLLNGDCNMALAGAISVRVPHRAGYYYRGGGIVSPDGHCRAFDAEAGGTVFGS
GGGIVVLKKLANALEDGDRIHAIIRATAINNDGALKTSYTAPGVIGQKNAIIDALSKAGI
SPETISYIEAHGTGTPIGDPIEIDALTQAFHTQTQKQGFCAIGSVKPNIGHLDVASGMAG
LIKLILALKHQQIPPSINFNQPNPHIDFASSPFYVNTKLSPWQTNQIPRRAGVTALGLGG
TNAHAILEEAPTGNDGDKEDQGDGYYLLPLSARSSEALKCLAKSYQDFLSTRPESLPDIC
YTASVRRSHHTHRLSLLVRSRDELLQLLETYLQGELHSQITTGIQTPDRQHLPIFIFPGQ
GSQWLGMGRKLLQQEPVFKAAIVQCDQAINQYTNWSLLEQLIFDEADSRLAEIDVIQPTL
FAVEIALAMLWQSWGIKPAAVVGHSMGEVAAAYIAGALNLEDAAKIICKRSQVIKRVSGQ
GAMAVVGLSLEQAQKVIVGYENCVSVAVSNGPISTVLSGDPKAIETILANLQAKNIFCRL
VKVDVASHSPQMEPLQEELRQLLQGIQPQAATIPIYSTVTGKLIDGLDLDTTYWVKNLRE
PVLFSTAIQSLIGEGHEVFLEISPHPILTTAIEQGLQYSDRQGVVLPSLKRNEDELAVML
NSLGAVYTAGYPVNWRKLYPDGENHIQLPTYPWQRQRYWLDRKIARKTPLPEETNKSAIS
EECTDLFYDLTWRLKPQQNSTSKNNQDSLWLIFSDRQGLGTALASQLQAQGATCYFVIPG
NSYSESSQGHFTINPTDPEDLQQLIKDAKASSQLPLRGIVYLWSLDIASAQVTETSLQDA
EKLLCGSVLHLIQALVKNPPSDWPHLWLVTQNTQPVKSSVNSQALPQSLLWGLGRVIALE
HPELWGGLIDLDKTTADQAAILLAEIQTADGEDQVAWRDGQRYVARLVTSTVPKALKPLT
EFNTDGTYLITGGLGGLGLKLAAWLVAKGARHLVLTGRQGLPERSLWNTLPPDDKHKKAI
TAIQTLEAQGATVKVVQADVSNFSQMQAVFASNTHWRGIIHAAGISIPQNLAEMSLSTYQ
NVLAAKVSGTWILHQLTQNLQLDFLILFSSAAAIWGSSGLAPYASANHFLDILAHYRQGN
NLPVLSVNWGSWDEINVVAAEVQSLWSRVGLKPMAVTQTLEALKLCLQSGVVQKTVADVD
WSIFKPTFEVRRHRPLLAELGQPQEKQENSAVSKSELLLQLEKSLAGDRHNLLITHLQMI
VSEILDLDPENPPENQQGFFQMGMDSLMSIQLKNRLEASLNHPLPSTLAFDYPNIEMLAN
YLTQEVLAPIFRQHLETTQDISTQPTSQNQSNSLDELFLQIESLSEDAVTQLFLN
>A0A1V4SJ95|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminiclostridium hungatei|TrEMBL
MKNIKTNKGIRLSQAKGADVTGIYSSKANLAYLLIDSAQNQKDKGITFIQNDDSEQFLLY
EEILQKALLRLGGMQKAGIKKGQYVLLVLNNNLDFIITFWACILGGIIPAPLIYPTSTRA
LNASLKKLEAVWNVLEKPLILSDSYLKESSDELNRIIGISGMEFEDVLTFDISSEGGEAD
LAEKGSTAYIQFSSGSTNTPKGVILTHGNLLTNVEAIIASANFTSEDRCLGWMPYHHDMG
LIGFHLSITALGMAQFNMTPYKFIKRPNQWLELISKYRITITGTPNFGCKLVLSRIKPEL
LEKLDLSCLKYICNGAEPISVSLAEEFMEKLSVCRLKKSAMYTVYGMAEACLAVSFPIPF
EEPLVHSVDRQVLVSKAKVKYVDRKLKNALLLADEGYPVNGTEVRIVDQKGSVVPEGTVG
EIQIRGDNVTSGYINNPEANRASFQEGWLKTGDTGFMLDGRLTVVGRIKDIIFVNGQNFY
AHDIEDVIEELEGVEPGKVVACGWHDETEGREKVALFSTLHIKDERAKPFYSKILKHVNE
IFGIPIDYVVSIPLIPKTTSGKIQRFAMVEAFRNNEYAGKVITAAELKHETMEETSEIVV
NRPGLAETICGIWSRVLERPASTIAYDQPFLSMGGTSVKAIQVLGLIEDELALKLTHDLL
IKCSTINDMEQYILNIHNNEELKDKNSFLDKTAGNRNSDENDDIAVISMACRFPDASNPE
EFWNNILKGKCSIGDIPKERWNIDDYYSSSPEFGKTYCRSGAFIKDVYDFDAGLFNIPDK
EAEIMDPQQRIILELVFELLERAGYSRQKVEGRKVALYIGAGTNLYNEYHLRTLNKMDLQ
NFESFALLSKEQQDSIMEEWKNRLGVTEAHTNILVDNILNMIAARASQEFNFKGPSLVLD
TACSSSLVTIHLACEALKRGECEMAIAGGINLLLTPTPYIYFSNAGALSVSSSSKIFDAD
ADGFVPGEGAGLIMLKPLKKAIEDRNDILAVIKASSMNNDGHSIGVMAPNPDGQRDVIES
LYCQNDFSPAGIQYVETHGTGTKIGDPSEIRALDNAYRNWNLGKNMIAVGSVKANIGHLL
SAAGIASFMKVVMALRDKKMPPQPNVATPNPMIKFPETPFYILKEEKNWKVEEGVARRAA
INSFGFGGTNCHIVLEENPVEADLLSEVCDEKPRHILCLSANTEAALEQKINNLSNFLEE
RKDYSIADVCFTENVLRTTFKNRYCAIADSTADLVEKLKKASLDINKSIALPKVALMFTG
QGSQYVGMGRALYEKLPAFRKYVDMCSDAFYPYLDVKITDLLYGGNADEKFLAQTNITQP
VVFTMDYSIGSLLLELGVKPLYVLGHSVGEWAAACIAGAVNLEDAARLVAARGRLMSQLK
VEGAMAAVFTSASGIEALLKPYEGSLWAAGYNVTHQVVSGKADTMDEFLKELQKKGVGSK
RLNVSQAFHTPLMKPMLEAFKKELEVTTFNTPKIPIVSNITAEIYTKLYTPQYWLDHILG
AVRFEQSVKYMFDKGINILVEAGPDKILTGMASSLASESNQILASMDRKKDNWDILLNTL
GKLFTLGVKIHWEDFEKDFSHKKVLLPSYPFERKTYMPDFGSGASGNLSRRFDNWFHEWS
WKSEKLVQISKLNDGAVILFAEDENTIKDFELSLESDKNKLYHVTYGKSFSYDGKQSFLI
NPLRQEDYFSLLDSIQGEISSIIHMWNYFEKSLEASRLVEQEEVLYKSAYSILLLAKALS
NRKLENLRLLLVTNKAFCISGEYEIQNPHQSIAIVLGQALDTEVKGLFTSVLDIDNEDYI
SGTEAAATIVDELGKKPNAEAIVAVRKKERFVRELEKAPISKLIEDKIYLNDNETYLITG
GTGLIGGSIAEAFAKRAQVNLVLTGRGELPPGEEWNENSAEAAAAKISLIRSLESKGAKV
AYFAVDVSDSTQMSEMVKQVNEEFGPIHGVVHAAGIMDSSAYKLLDKDLETFKNVLAAKV
NGTIVTDCVTNKEPLKFFVLMSSVSASKKKWSAGITDYAAANYFLDCYSSYRSKSNSPGK
SLAINYSLWEAKGKGIISGEASELAVKAQGLRPLPAEGAVEAFMQALNYKNQNVIHIMDL
MEAKEEIKPLRKETKAAYEESRMKVSGKTANEIRSIVYGTIAEELNADADNIDEGMNFLE
MGLSSLDVTKIVARISKALGAELYPTLIFEYQTPEAFTNYIEKTYAVSEGEIAAVAEENL
LYAADKNKEDIQDIAIIGIGLRIPGADTLEEYWDILKNGKCIIKEVPKDRWSAEENYSDD
KKLLHTTYTNKGGFIDKPYDFDPLLFGMSPNEAEATDPQQRIFLQIAWEALQQAGYGGKY
KSNKIGVFVGCEQNSYMEHFTGYRTYMLLKNKLEQSEAYKGMKPKERRELMTNILQVLNP
GQLVADAVAGSGLNEIAARVSHCLNLSGPSLIVNSACSSSLVALHMACESLRTGQAEMAL
AGGVNLNMSATPFVSLSRVTALSPSGNCYPFDKRADGMVLSEGASAVLLKPLKYALEDND
NIFAVIKGSAINNDGHSQGITAPRPQGQAEAIRNAYITSGINPETVSYIETHGTGTPLGD
PIEIEGMTQAMRSFTSKKNFCGVGSVKSSLGHMLSAAGLISLIKVVLALNNKTIPHTINF
EEPNTNIDFSNSPFYVVGKEPREWKAEGSPLRAGVNAFGFGGTNAHVILEEAPLITNTGT
ESEEERQHNVIFLTGRNEKIVQAIAGNLIAHMKKKPELDLSSICFTMNNSQKELTFKTAI
VTDSKEHLLDMLLKLEKGEESSELIKGRSNPNRVTPVSLVMDCSFELDKKDCDKIAKRFS
GFAEAYNKCMQIFEKEGSGGPDSQLAKTVESFALQYAFGALLCDFGIKLKSIICEDNAIL
AGGALAGIITIKQAARFLINKAGYKNNELDESTGYELNCPVVTPLGIADKTNIFDLVSSI
RGEARGKLSLDSCKEIINKDEAIVYLGSSKTKGNEFEKMKFNNLQWIEMSMSQNCAAAIL
AVMAKLYTTGVSYNPSKLSWHKARRVPLPTYPFENSEYKVSFKDESLEADNNEYSEEKTN
NFASTNELVDFKEASARLALKKLNTQEAISGEAKACSIEGLRRDLSKI
>F1TIW0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
MADQFNKLFNEIKERKITDKDAIDQIKKLKYQKNMTTSDKENKIGEVVFGKQFVYDENLL
KDHKIFGNQILMGVAHCSLVLQALVQMSEKCDMALSNIIFLDPIQVLPSETVKLDVVLKH
QNKSILFENQYFKRSVQKMVVAASGQIIADNIMRLDETIVISDWISLAIKTISSDIFYKA
ATQDTYGDTLFSVRKVHVLSRGVFSEIELAPEMKEEAKDYLCHPAIFDAIHVTSTFAVDP
DNPLIHHWVPFVINELQINNGVSEDIYGKLYCYAELIKSNSEIKEFNCKVYNQNGKQIIN
VKQLCTKRIPSREAFLGISSVNISSPNLKYTQDSTVVLHKKPNEPIGNNSVPIKEKIQEY
LKKTIAEVLGISRKETGIDKNFMEMGADSRTIMAVSQKIQEEIGFVLLPTVFFEYQNIVE
LSSYFAEEQSAQFAAYFGVQQSTDLIFSQEQANNIIKSTLVQRQQAALKESKLRDAYSYS
EDDIAIIGMDGRLASSPDLNSFWKHIVDSKDLISEIPMSHWDYQPWFDENRHADNKTYSK
WGSFIEDVDKFDPLFFDISPRQATWMDPQVRILLEVVYGVLEDAGYINQIKGSKTGMYTG
VCFQEYWDEIVRKRIPITSYEHVSSSMSTLSAHISYTFDLHGPSIPLDNACASSLTAMHL
ACQALKTGECDLAVVAGINLLLSPLHHVYFSRMQALSPTGRCHSFDKQADGYVPGEGVVA
VLLKPLSKAIKDQDNIHAVIKGTAINHGGRSNNLTSPRPELQTEVILEAWKNANISPETL
GYIECHGTGTALGDPIEVSSLQKAFRKHTSKTNFCAIGSAKAHIGHLEGAAGLTSVLKVI
LSMKHKKIPQMPNYKEMNPIIKLEDSPLYINTEVLEWKTEGSTPRRAGISSFGMIGNNAH
VVIEEYVPKQKRPQIQVTHENPAIVVLSARNTDRLREQVERLLSAIRTQGFSDNDLADIA
YTLQVGREGMEERLAVIAGSIKELEEKLKSFLEGQDDIPDMYRGQVKHNRETLAVFTADE
DMQKAIEAWVVKGKHVKLVDLWVKGLIFDWNKLYGETKPCRISLPTYPFARERYWMPDIE
STPAVHKNTSHLFKKRSASTLTGRKLDHAASKSNPVQEAQEAFELMTFEETWQEQVLPDN
SSARIKAMVCFLSDSKKQQAAIEAVQALDGQTRVIFISQSTSYRKQSEQAYHISPKDPDT
YKDAFKSIREDYGNIDAVLYLWPLEDKKHIRDYSCIVHILQGISFSKLKPSHILLAAQYE
DMLERCHLESWIGFERSLGLVMPDTRIAAIMQESEENREPDIKDWLQKLWREMPTPKNSS
ILYQEGKRYICRIRPTKMQPGNSLLKPGGTYLITGGCGGLGLQLAGHLAKTQHANLILTG
RSPMDEKKQMKIKILEDLGGQVLYLQADVCDQARMKEGLSQAKERFGEIRGVVHAAGLAG
GGSILDKDISSFEEVLGPKIKGTIILDELLCREPLDFICYFSSSAAILGDFGSCDYAVGN
RFLMAYGHYRNNQQPGKAVVINWPLWKEGGMGAKEGDNAEMYLKSSGQRFLETEEGIFMF
DRLLAQNNIQHLVLAGQPGRVHSFLGLAGNQSQAQTPDIYKPSGKGRRTEMKGLSLEQCL
EWDLKELAGNVLKIPREKLDKEENFADFGFDSISLARFATILTGHYGIEITPAVFFGYST
IERLTQYFFTEHQQAIQNFYREDAAKQAVLQKAPQAASSEQGAGSFMLAVDSTPQSIPEP
IAVIGMSGRFPGADTVGELWNNLKDGRECITEIPASRWDWQKYYGDPHQEDGKTNSRWGG
FISNPDQFDPLFFEISPKEAEVMDPQQRIFLEEAWHALEDAGYMGEKIRGTSCGVYVGVE
ESQYGMVTGGKGQLNSNQNATLSARIAYLLDLKGPNLALTAACASGLVAIHHACQALRQG
DCNMALVGGIGLLVTPMIYLALSQADMLSSDGKCYVFEQRADGLVPGEAAAVVLLKPLSK
AISDKDHIYGCIKASGVNYNGRGNGITAPNLVSQTELIKNIYNKYDINPSNIQYVLSHSV
GSKFGDSIEVEALTNSFKQYTNKKQFCTLGSVKPLIGHTFAASGVVNLISMLMAMKYHTI
PALPNHEAKNEYINFIESPFIISKENQAWITENGQKKLGAISSTGISGTNAHAVIEEYLP
PQEEPICPLKDLPQIIVFSAKNPDRLRVIIQQMLDFLNSESSAGIRLPDIAYTLQTGRDA
MKERVAIVASSKQDLCSKLEAIISSRHAEMFPKEIITGNIEKIKEDSKKQLSDREGIEII
IKNALEGRNLNQFALLWVEGFNIPWEKLHQDEAVKRISLPAYPFAKRRCWIDINQNNNPE
EKCAATLEQEYKNKAVELYTIITRDSKKEFQEEYLTFCPFEEKIPGFSMSRVFLHPEQFA
AEAELVKAKQIEMRQVLFCKEDFNQIKKLLDIGCGHATDIIQIAALYPNIKTHGFTITKA
QAELGNQRIAEMKLGSRAQVFNRDSSKAPFPDCYDLIIGIEVCCHIRDKHSLFKNISASL
DEDGRVLLMDFIANLRGSIVDPNIEISIATSKDWIDIFSTYNLVIDEIIDVSRQIANYTY
DLELEQNIKHLPEVSQNSLRNYANQSLSIEQGWLSYCLFKLKKDTKRSKSELLEDNAYKL
AHKTPYSKALTEMLDQGYIPYPKSLDKTFSNQQNDSKNHQLIDNKIHTGILKDLTIISEI
LREEFLTVLGLERTDLEEAETFQGLGVGSINAVKLLEAINTRFNLDLPTSVIFEFNTLDS
LAKYIAEYVPELTEQIMSVNQAAGQLQEVLSEEKHTKVNVVSNLDTQLQKSTDDIAVVGL
SCRCAGANGQNEFWDLLRQGKDCIQEIKKQSWLDFFDANSLNMVPSRYGAIEDIEFFDSL
FFKISPKEAESMDVAQRILLQECYKALEDAGYTPSSLQGRQVGTIIGTMGNVSVTQDFSH
FSMLGYDTSILAARIAYFLDLKGPAMAINTACSSSLVAVDTACNKLKNHEIDLAISGGIT
IYSNPGAFITMNNAGMLSPTGECRPFDNEANGIVVGDGVGVVILKRLKEAQRDNDFIYGI
IRGSGTNQDGQTSGITAPSFLSQSQLQESVYRRNHIAVEDIQYIEAHGTATKLGDPIEID
ALSDSFKKFTARKCFCAIGSMKANIGHTTAAAGVLSLIKVLLSMKNKEMAPSINFTKGNE
HIDFENSPVVVNTTLKEWPVNSKGSRLAAINSFGFSGTNAHIVVEEYPANSQGSVKVEGA
TPGLLVLSAESEEVLREYARETKEFIQACNDFNLADLLYTFQVGRASMSYRLALLSNNKE
MLLAKLEQFIEGNVPIDSFFGKTGKNNVINLGDTEEGKEYIQRLIKNNNTRKLAELWVNG
NQIDWKVIYQKGAVRRLPGLPTYPFAKKRYRIPEIEVKPVSSTAAIAPAIHPLLHQNTST
LAEQRFTSVFTGQELFLADHKINGQNILPGVAYLEMARVAIEKAVGASDEALIRLEDVVW
VRPITVEGQPIQVHIALYPEETGRIAYEIYSQPDQNNTKPIVHSQGAAVLGIAKEPPVLV
LKTLQTQCTQTILSASQCYGAFKSAGFDYGPTLKGIERVYVGSGQVLARLSLPTAISDTQ
CQFVLHPGMMDSALQASIGLMMSMVSSGGGIGSKLSPPFALNELQIFGGCTSAMWAHIRY
NDDNVSGDRVLKLDIDLCDEQGRVCVRMKAVSLIMLEGDIQIGNPEKAVSYETSIKPLVG
TFMMKPVWDVDLIEKGQALPYPTDRVVIAGDDKGDRSVIMQYYPNAQVLHIQSDDTIEAI
VKRIKEQDSIDHILYIVPYRPLKSQADEALIEEQEKGVLQIFRMIKALLRLDYGDKVLGW
TIITVQTQPINKNDVVNPTHASLHGLVGSMAKEYPNWQVRLVDLEADCTWPMEDIFTLLP
NPQGNPWIYRGQEWHRQKLIPFQSPPFEWTLYKPEGVYVVIGGAGGIGEAWSEYMISTYH
ARIIWIGRRQKDETIQAQIDRLAALGPEPQYISADAANRNALQKAYEQVKQLYGQINGVI
HSAIGLLDQSLANMEEERFRGGLLAKVDVSVRLAQVFKQEPLDFALFFSSIGAFAKDHGR
SNYSAGCSFEDAFANYLSREWPCAVKVMNWGYWGNVGVGSVIPQVFKNSIAMAGLSSIEP
SEAMDALERLLTGPIDQIALVKTTKPLVMERINPQEQIVIYPENIHSYIHKIKNRILKQG
LQDKNMKLEIGVHMQEIDSLLCKLLFGQLQSIGLFTEKNFMIDDLETKGLNHLLKRWLAE
SIVVLTSNNYLSFDKEVYTVADPTPIGIEAVWNEWHLKKHPWLNEPNTRDKIILVEATLR
ALPDILTGKVPATDVMFPNSSMELVEGIYKNNPISDYFNGNLADTLVAYIEKRRQDQSGR
LRIIEIGAGTGGTSEMVFEKIKPFRDYIEEYCYTDVSKAFLLHAEKEYGSDNPYLTFQIF
DVEAPIAKQNISAGGYDVVIAANVLHATKNIRQTLRNIKAILKKNGLLLLNEISGNTLFT
HLTFGLLDGWWLYEDTALRIPGCPGLSSQTWQSVLEDEGFQQVFFTAQEGHVYGQQNIAA
ESDGVVRQKLLEPDTEKKKDGMTLKKPQKFPVRKVGGPTQDLIREKSTAYFKKIIGDILK
IPCNEIDSSEQLESYGIDSILIVQLSNTLRKVFENISSTLFFEYQTIDAIVDYFMKTQRS
SLISLTGLEDNNPTEGQGSDEEIFIPPNPLHQNYTFRVSEHPFVLHKRPIENPESQQYRE
PIAIIGLSGRYPQAKDIQEYWENLKAGKDCITEIPEERWPLEGFYYPNSKGAIPQGKSYS
KWGGFIEGFADFDPLFFNISPREAINMDPQERLFIESCWGVLEDAGYTKEQLATKHNQRV
GVFAGITRTGFDLYGPDLWKQDEKFSPYTSFCSAANRVSYLLNLQGPSIPIDTMCSSSLV
AIHEACEHIHNGECEMAIAGGVNLYLHPSSYIGLCAQNMLSADGKCKSFGRGGNGFVPGE
GVGCILLKRLSQAVADEDHIYAIIRGTRINHGGKTNGYTVPNPTAQGEVIRTAMDKAGVD
ARTISYVEAHGTGTELGDPIEISGLTQAFRKDTHDTGFCAIGSVKTNIGHLEGAAGIAGV
TKILLQMKHQKIAPSLHSSELNPNIDFAGTPFIVQQELAEWKRPHIKIDGETSEYPRIAG
ISAFGAGGSNAHAVIEEYIPKLKRPQIQVTRGNPAIVVLSARNADRLHEQVERLLNAIQV
QRLSDTDLADIAYTLQVGREGMEERLAVIVVSIKELEEKLKSFLEGRNEIPDLYRGQVKR
NKDTLAFFTADEDMQKAIEAWAVKGKHTKLVNLWVKGLSFDWNKLYGDIKPCRISLPTYP
FDRERYWVPESKKQIETTSLPLQSSIQFDEKFYDLLIDEIMKDTISIDTAIQKAEDFISM
QNGFPVLGGEL
>A0A3N6EJK6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-17|TrEMBL
MPKAYVFTRHGGPEVEALIEQDVPVPGPGELLVAVRAAGVNPVDWKLRTGYIRPGSELQP
FPTVFGSEAAGVVEGIGPDVEGFAIGDEVFGNPVTGGYAEYTLLPVAVTAHKPDGLSFTD
AAVLPVAAATAYDGVRQLGLTPGSTLLITGAGGGVGAAAVQLARHAGLRVVGVAGAAKKD
FVESLGAVHIEPGPGFADRVRAAAPEGPDAVFDLVGGDTLRAVAPLLADPAALISAGDKP
LAVELGGAAVERARNAAVLDEVAKLVATGALRTHVNRAFPLTGAGDALRAVESGHTLGKI
VIEVVA
>A0A2S9YGC6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Enhygromyxa salina|TrEMBL
MSIWKHDAHHPPATVDTVTALLRHRAQTAPERVLYRHLVDGETVSGELSVASLWSAARAQ
AAALASAHPQLRPGDRVLLAFPQGLEFGVALLASALAGLVAVPVPAPDPARPERDRGRLE
AIAADAGAVAALSLGQWAAGLEALGELAKLDWIDVEALPELDDEAVRAWSPAPAEPETPL
YLQYTSGSTSTPKGVVITHSNLLHNCANLNEAYDLQPDSVMVYWVPTYHDLGLVYGVALP
LFIGFCAVSMAPRDFLARPIRWLRAIDRFGGTHSVTPNFGFDLVVAKTRPEDCEGLELSK
WRHALNGGEPIRAHSEARFLARFSSYGLGEDVISHSYGMSEATAELTAEAVGERGVFLDV
DREVLAGGRVELASPGSPGAQRIAGCGRPSGDTRILIVDPERRVARADGEVGEIWISGSS
VAAGYFSSPEASTARFGAELSEGPPGVWLRSGDLGFIRDEQLFVTGRIKDLLIVRGENYY
PQDFEWAVQDLHPALRPSAAAAIVVDDGDAERLVFMTEVYPERTDDLRALFALLRRELGA
LGVQPATILLLGPRALAKTSSGKIQRGEMKARYLAGAIEPLARWDVDADLRELDDARLAA
VRASAGPERVVEIEGLVSSLVRAKLGVGAEHEPGADAAPLIELGLDSLALVELSEALSHA
LGVRVGLSALSQPRPRAELIAELAALGPERGDDPATPALASGADGEDRHAPFALHGIQRA
YWVGRAGGELGGVSCHSYQEFDARGLDLDRLARAWRALIDRHEALRLVIDDDGRQRILAE
VPAYVIAVDDLRGLDHRARDRWLAQQRERMSHQVLAADRWPLFELRAARLDDTQTRLFVS
IDLLIADGASIGLLFDEWRRLYADPGLELPALPAYGFRECVGHEQQLRGTPAYAASLSWW
AEQRPSFATAASLPLACAPEELERPRFVRRRQIIPRARWDRLVAQAKRCGLTPSVVVCAV
FVEILEAWTGAQPFALNLTTFRRPPLDPRIDEIVGDFTTMAFLRCDRPEPGPFDALARGL
QAQLHAQLDHRIVHAVDVLREWSRAGAVSIPVVFTSMVRGDGSRRFDTAWIGPEVYAISQ
APHVWLDYQLLECDGEIVSRWDAIEGLFPPGLLDAMFAALDRRLASLADDPRLWQAPTPE
LLPPDQRAGIDQANDDTAPLPAQTLDAVWDAQVARSPEAEAIISTARTLSYAELDLVSAR
LAAALLARGVAADELVAVIVDRGWAQPVAALAVVRAGAAYLPIDTSHPSERCVALLERGK
VRVAVTSAAFEAAQPEFPWPAGVERLYVDELPVTEVEGYDRAALGRPEGRDLAYVIFTSG
STGAPKGVMIEHRSAVNTIVDVNARYAVLGSDRVFGLSSLGFDLSVYDLFGMWAVGAAVV
TPTEAERSDPERWEPLLRRGVSIWNTVPSLAQLLVDYAEDRPELAEAMASLRVIMMSGDW
IPLDLPDALRRVVPHAQIYSLGGTTEGTIWQVEHPIGEVDRSRPSIPYGRPMTNHRIHVL
DRWLRPCPTWVPGELYFGGVGVARGYYADPERSAASFIEHPITGEYLYRSGDFGRWRPDL
TLEFLGRRDRQVKVNGFRIELGEIEARLASHAAVAEVAVVVVGQRPPRLVAHVGLAGAAD
HDPGQLIAALRSHCALSLPAYMVPAAWQLHADRLPRSSNAKVDRGGLARLGLPPAPGSSA
SPARPPTQPGGGLDGERFELVAREAAAAFELDREQLDPDATFASLGVDSVAALRLRSRLQ
RVLGRSLPATLAYDHPTLRALVAALGAGEDAAASSAEVEAPGPHAERDEIDEPIAIVAMG
CRFPGEIDSPDAYWQALVEGRDVTSEVPRQRWDIDAIYDPRAEASGTTYCRRGGFLGDLS
GFDAAFFEIAGREARGLDPQQRLLLEVGWETFERAGLRPRELAGSEVGVYIGLSTEEYRW
MDGHSLAEQLDGYGVTGATPSTASGRLAYAFGLEGPALTVDTACSSSLVTVHLAAQALRA
GECSMALAGGACLLQSPTLFIEFARLGGLARDGRCKSFSAAADGVAWAEGVGLVLLERLS
DARRHGHPILALIHGAAVNQDGRSNGLTAPSGPAQERVIRRALRSAKLGPEAIDYVEAHG
TGTKLGDPIEAGALERVFGRGRGSTADPRAPLWLGSVKSNLGHTLSAAGVAGLMKVVLAL
VHEQLPPTLHVDDPTTHVDWARSGLALVSEAQPWPRGADRGPRLAGVSSFGVSGTNAHVI
VGEAPVDELEAAERAVEAGPLLIVSARTDEALREQALRWADALEQLTDEAWPAAVATAAH
HRAHHRVRAAVHVGDRRSGIVALRQLAAAELRPELIRGAKQGGPSIAMFTGQGGQRAGMG
VELYQRLPEFRAAFDEVEAAMTAAGGLARPLLELCADAEALAQTGVTQPAMFAVEYALAR
QWQGWGLRFDALLGYSVGELVAATIAGVFSLDDAARLVCARGRLMQGIDREGAMAAVSVA
PEQLVSELGAGVEISAYLGPGRCIVSGDRAAVEALGLSLGARARFRRLEVSHAFHSAHID
EILADYAEIVASCERRPPALPIISTLTGRRASSAELRSVDYWVRQAREPVRFHQALEASR
DQGFRVFVECGPDAVLTGMAASSLKVSSTSTSTSTPGACACVASVRGQLGELASMVRAWA
ALYVRGVELDARVLGPRADRLLALPTYPWQRERHWREPPAAVGAGRRARFDLGGVYRETP
DGGRVHEIPVSLGHQPYLADHRILGRVTAPATLHVAALLAVSAELWPGEAVTLEDVVFAA
PLLLDGEAPVTLTAQLQPNASNSNSNSSSDLGAGVWQVRLATRVDGGWLTHVSARLERGA
DPDAWALEIPASPVDLELGFDDLVDALAAVDVSWGPGWNALDGLERRGRFVEARLRDELA
AEGRAHAPISPVVLDNASASGVALRWPPTPDDDVPRIPFAIERLRWTGASAGVASSRRWL
RGELDGEVEGASLSLHGDDGRCLLTIEGMRIKRAPRASFLLAAGRERVALHRLVDERVDA
PLVEVAGSDPVVIGDPGLAASLGWPAAVDLEAAAARGPERVLAVIGARRVGASPDTIADL
HAAILEAVARVKSWLRWCEASCELTLVVGVEAPVLHGALAGLCGSVRSEHPDRRLRLIAC
DAELDAERAARALALDEPELRIESGRISRPRLRSVERDPQAPSRVSLGLDEGAALITGGT
GALGQLIARHLVREHGVRSLILVSRAGPSAEGCEALRAELEPLGAELRVIACDVSDRAEL
GACLETIEQPLASVFHLAAVIDDGLFTDLDAARFEGVLGPKLDAAVHLDELTRAQPLRHF
VLFSSAAGILGSVAQSNYAAANAGLDALAAQRRSVGLPGQSLAWGPWAERGMSAALADAD
LARMRRVGLEPLDDARALALFDAALRRPESSLLLADFSPRRASTTRPRARLRGLGGARVG
SAPELGHELGHELGHELGRELAGLEPNARAARLLALTRQALAVALGVRGPEVVEPDQPMR
ELGLDSLMAVELRNLLVERTGVSLPTTLAFEFPSARAIADHLDARLAELADPGVDPARPP
RATRAPDRGEQDDAIAIVSIACRFPGGVETPEQLWALLVEGRDAITEVPSTRFDIDAWYD
ADPTRAGKTYARTGGFLGPVDGFDADFFRVAPREARSLDPQGRLLLECAWEAFERAGLAP
RAFEGSNTGVFVGVCGSEYLVEALADPARIDAYSLLGTTHAAIVGRLSYALGLRGPNLPV
DTACSSSLVATHLACAALRSGECDLALAGGVNLLLSPAGYVYFSELRALAPSGRCQTFSA
DADGYVRAEGCGLVLLERLADAEREGHDIVAVIRGSAVNQDGRSNGFTAPDGAAQRAVIR
QALARAEVSPSSVDFVECHGTGTVLGDPIEVRALAEVYGEAREQALAVASIKSNIGHAEG
AAGIAALIKAALCVREGLIPPTLHVGQLNPNVDWDSLPIRVAREALDFCGAGPRRAGVSS
FGFSGTNAHLIVEQAPARPLDAREADSSSLGGARPLLISGRGRGLAEQARRWAAQLRARP
DTRLDDLVHTAALRRAHLPDRAFASVDSLAAAIAALEALAAGHPHPGLERGHAEAEPAIV
FIFSGQGGQWSKMGRSLLGASPRFAAALEAVDDVLAPLTGWSVQALFSGRLELDLERPDV
VQPALFGLAVALAATLRGLGVEPAAVCGHSLGEVAAAVVAGALTLEAGAELVVLRSRAVL
ELPEPGAIALFAASEAELVAQIEADAALRDQLDVAAVNGPRATVVAGRAEALAALMRWAR
ERELYCREVQMGYASHSRLVEPALAGLAEALEQVMVAELGPRPCTGPRLYSSVRAAALDG
RELDAGYWCANLRERVRFAATLDAIVEGLAGAGEAPSTRPIFVEIGPHPILGPALESCLE
ADAERPASVLATLDRGTDDRAALLQVLARLHLRGVEIDWASAFEPEVAGHVDLPTYPWQR
ERHWLAPRSRADAAALGLDPLDHGVVHGVTTLAEGGLLLGGRLSAGEQPWLADHVVLDVP
LVPATAWLDLALVAAARAGAPGLRSLSLERALSVDASASVQLQLRIEGEALEIFARASTP
AGEGEGEGEGEASWRRHASASLDLRGDAEPLDGAPLRWPPSAGEGVDLDALYERIEAGGL
RYGPSFRGLVEARREGDTAWARLQLPVSTADEGRDCLVHPALLDAALHLLGLFEVAGLDD
QGGDSALLPVDWRGVRRRVDAELGRELVARVEWLGGDSEAASLRLVVADHLGTPALSVDS
LRFRRVELAQLAPVRRQRPSAPLLHMSWMPVELDDAREPADALAVVGDAALAALLERPCF
ASLDALLEAPGPVPATVLVALEREHDLDGVPAEARQLARRALELVQRWVTSAALDGTELC
VVTRGGAGACPSNPAAAVAWGLVRSAAREHPDRRLRLLDLGDTLGSRPQLAAALASAELE
LVLRGHEASTPRVAPLAPDALAPPALDPERWVVITGGSGALASRLAEDLVRDHGVRRLAL
LSRRGPQAPNASDLERRLVELGAEPRLLACDVGDREALAAALSSLDAPPTGVFHLAGALD
DALLGHQRAAHLERAFAAKLDGAWHLHELTLADAPACFVLYSSLAASLGGVGQANYAAAN
SVLDALAAYRRSLGLAATSVAWGLWTEGQAGMAASVDGRTRSELRRKGVLEVSPDQARRW
LAVALQRSEPQLIAARFDPRRLAASRDLPATLAALSPRRRPDSSARARFAAELAALSDDQ
RLAHVTAVARDAIAKVIGGSAELVGPDRLLSDLGVDSLMAVSLRDELGERVGLRLPATLG
FDYPTAARIAALILRELDRATALERPREPSAPAARLAPAAPADEGVAIVAMACRLPQGVD
DPEQFWRVLDEGRELLGPFPERWDPGVYDPDPDALGKTYARAGGFLDGIAEFDAGFFGIA
PREAEAMDPQQRLMLETSWEALERAGIPGQSLRGSATGIYVGAFRSDYGRPESALDAMDG
YGGTGTATSVISGRIAYFLGTHGPAITVDTACSSSLVALHLACAAIRAGECERALVGGVQ
IMATPATFVEFARLRGLARDGRCKSFAAAADGAGWAEACVALVLEPVSVAQRRGDPILAV
VRGTASNQDGRSQGMTAPNGPSQQRAIQRALARSGLRPEAIDYVEAHGTGTKLGDPIEAG
ALAEVFEPDRRQGPLYLGSSKSNVGHTQAAAGLVGVIKVVLALIHERLPKTLHAEQPNPV
IDWAHTSLALVQTNTRWPREPGRPRRAGVSSFGISGTNAHVIVEEAPGVDPRSPVPPPPT
TAAAPLELGPLLLSASDRAGLRGQARRWLAWLDSREDPPSWAATVHAAAVGRSHLLHRAA
LLARDLDEAREQLAALAEDREHPQVVRDESRASMRVAFVFPGQGSQWPGMGRALLASSAV
FRGAVEACERALAPYLDWSLAAVLRGDPGAASLARVDVTQPAVFAMAVGLAAVWRELGVE
PVAVVGHSQGEIAAAVVAGALSIEDGARIVALRSQLLVELGGGGAMLAITHGRDEVEACV
QADPRLTLAAINGPESFVVAGPGEAVDRLADGLRERGGFCRRIAVDYASHSSEVEPILPA
LADHLAGLRPGATRVAMHSSVTGAVITGPELDGDYWCRNLREPVRFAAAVEGLVAGCDAV
LEISAKPVLGVPLSRLVDPRTPVLRSLDGDQHEAGVTALVASLAALHCAGLALDWSALLA
ARERVEVPTYAWQHERYWLEPAPVERRGAHPLLGPGARTSLEPGAWIWPVRLDLNASPAF
ADHRVGGRVVLPGAATLDLFATAAEAIVGGEGRARLETIRLLAPILPGEAGVWIGELVAS
RPDALGGASLRLLGLDEQGAWVETASAELVVEAGHGPTPTWLELDEDARERFTTSCPDSV
SPIEHRARQLAHGLELGPAFGCVESLSRGPGRASAALTLGPEQAVATRAHTLDPLLLDAA
LNLAGVVSEAVEDDAGLWMLAGIERLRWRGRVGRRGRALAEASTDEREQARVRVGLFGAD
AAAIEIEGAELRRVARPAWAERRAPWLGLRWVSEEPEAAAPSAPTLDRQRWLVIGGEAEP
ASRLIDALGAALGRRGAELIRAAGGVSEAIATTDRLTGVLVLGQLARTPMPGVAIEAASA
RACATIHDLVRALTGAAAGPELVLITRGSQFVVEGDARAVDIEAGDALPPGLADAPVWGL
ARSGVMEHPELGWLRIDLDAAASDDPEAQATREAELIVRALGPTPAGPRPDEIAVRGGQR
FVARLVREPEASLARRASPSAVVRAEASYLIAGGLGSLGLLTAGWLVELGARHLVLLSRT
GLRDPAQAEAIVALERAGAAIEVAAVDLCDPGALAQLIARFGADLPALRGVFQAAGVLAD
ALLLDSDPEQVERVLAPKLRGSLNLHALTRDRELDHFVLYASAAGLFGAPGLSSYAAANA
FLDALAHHRRGLGLPALAIDWGLVADTTMAARARAAGVEDKGMTPLGGVELEGLFAELLT
IDRPQLGAADLDTRRWLAAAPFARRSARFAELVAELERPDDHAGLGRRLADALASERLEL
LIRFVSGEAAKVLRLRSDRIEAGRPLAELGLDSLMGLELRNRLADALGEALPATLVWTHP
TVAALAADLLERWSASSAQAALEPVPPSGLGPDAELLASFDAELERIDGLIDPS
>E6U7B9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ethanoligenens harbinense (strain DSM 18485 / JCM 12961 / CGMCC 1.5033 / YUAN-3)|TrEMBL
MNIKQLRMLNPGGTRPAGPENRADDGIAVIGIGLNMPFADTPDTFWDHIENGIDCNRPIS
SYRKKLCPPVHQAKPADAFHYASYLEEIDGFDGAFFGLTPREAMLMNPAERLFLETVQHT
LEDAGCVVGSENRSVGVFVGLSSDIEWAKYRELVRQTEPEYMSSGIEGLYAPMVAGYASY
YFDLHGPSQITDTACSSSLVALHNACTAIRGGECDMALAGGLRVMTLPVIDPNYRFGIES
SDGFTRSFDAGADGSGTGEGVAAVLLKRQSDAVRDRDHIYAVIRGSGVNHNGRSMGVTVT
SPEAQGTLLSEIWRKAGIDPEQIGFLETHGTGTPLGDPIEIDGIANAFARFTDRKQFCAI
SSVKTMLGHLYDCAGITSLIEAVLALSRRKLPPLVHFNRPNRALDLMDSPVYINTKCRAW
ESDHPRLCGVNSFGVSGTNCHVLLEEATPSPAPAAVPAALRLFVLSAKTECTLKRYCDDY
LAFLRAHRNISVDNLCYTAAVGRKAYACRFAACVDSVSALSAALDRFRSGRADGSFFCNT
PGIAGPTGLDGGGSELERIGKLYCSGRTINWTDVFSGGSFQKLSLPVYPFEHVPLWPKLM
SGDHREFYFRFAWRERALARQETAQKQPVLFCSDGSAQAEAIRTALVERGVHAISTRFCK
RFEKRANSEYSLGSSAEDSTAFLREMQEGRWKKIVFFRASEKSRMARETLDALKETVENG
LYRMLSLVKAIEKQDVSQKAEFIVVTDRAEEVTGEETELHPENAMYSSLGKTVNQECCRV
KCRVIDLDEHTSPAAAVDEILFGKDQAVALRNDRRLIQRLEPVHLHKTENGNDPFREGGV
YVITGGSGALAAHVAKWIAARRGTHLILIGRSPIDPGHPAAGGSQAARTLETMEAIRALG
SSAEYIQADVADERAAAEAFDRIRRTYGRLNGVIHMAGITGNRMIVNMERSDFETVLAPK
VFGTWNIDRLTQGDDLDFFLLFSSGVSFIGETGLAAYAAANQFLNSFAQCRRRTRSVQAF
DWVVWENQRMMDGYSRNVDGWFEQIRPNDALACMRELMPRRESGLLIGRLNRKNRYEKSM
FSHLPFEVSEEVQRMVRITERAAAPDHTETGRRAASPHPADPRTIEGTLTGIFREVLGYQ
EIDIHDNFFDLGGNSILLKKLHQKVDEAFPGQVEVADFFAYTTVSKMAAHLAQTAGPATA
TMQEAEKPDDKLLELIDSIDSDSDVDAIVAQIENM
>A0A2K8P9X5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces lavendulae subsp. lavendulae|TrEMBL
MVSLAEVWGAAGVRPGAVIGHSQGEIAAACVAGILSLEDAARVVALRSQAIGRVLAGLGG
MVSVPLAAAEVRERIAAWGEERISVAAVNGPSSVVVSGEVQALEEFLAACERDGVRAKRI
AVDYASHSAQVELLREELGTLLAPIAPRAAGVPFLSTVTGEWVEGPELDGGYWFRNLRRT
VELERATRTLLDQGFGVFIESSPHPVLTVGLQETVEDAGREAAVLGSLRRGEGGLERFWL
SLGEAYVRGVTVDWDAVFAGTGAQRVDLPTYAFQQDHFWLESGTAEDTDTAAHPVDAVDA
RFWEAVERHDVAALTAELDIDADESLAALLPALSSWRRQSQERSTVDGWRYRITWKPAPE
PAATRLDGTWLVAVPQAPADAEQAAAVLHALAEHGADVRQIAVPGTHDARAELAGLIREA
LADGPAVAGVLSLLTPVGSDAEPIGAAAPAGVIATLSLVQALGDAEVTAPLWCVTRAAVS
VARSDRRTDPAQAPVWGLGRVTALEHGERWGGLVDLPAEVDARVLERLVGVLAGDGAEDQ
VAVRSSGLFVRRLVRARLSETAAVREWRPAGTTLVTGGTGALGAHVARWLAANGAEHLVL
TSRRGEAAPGAAELREELTALGAGVTLAACDVSDREALAALIAAVPADRPLTAVVHTAAV
LDDGVIETLTPEQIERVLRVKVDATLHLHELTRELDLSAFVLFSSFAATFGAPGQGNYAP
GNAFLDAFAEYRRAEGLPATSLAWGPWGDGGMAEGAVGDRMRRHGVIEMDPERAVSALRH
ALDRDETTLTVADMEWKRFVLAFTAGRARPLLHDLPEARQALESGRGDTAEDTGGAAVLV
RQLAGQPEAEQERLLLDLVRTAVAAVLGYAGPDAVEAGRAFKELGFDSLTSVELRNRLNA
AAGLKLPPTLVFDYPTPTVLARHLRTELAGQGAAGGTTPAPTPAGIAPGGDAEPIALVAM
SCRFPGGVRSPEELWQLLAGGGDALSQFPADRGWDVEALYNPDPDAHGTSYTREGGFLAD
AASFDPAFFGISPREALAMDPQQRLLLETSWETFERAGIDPETLRGSQSGVFVGTNGSDY
SHLVRGAATEGLEGHLATGSAGSVVSGRLSYTFGLEGPAVTVDTACSASLVALHLAVQAL
RSGECSLALAGGVTVMSTPGTFIEFSRQRGLSTDGRCKAFSSDADGFSPAEGVGMLLVER
LSDARRNGHPVLAVIRGTAINQDGASNGLTAPNGPSQQRVIRQALANARLTPAEVDVVEA
HGTGTTLGDPIEAQALLATYGQDRPEGRPLLLGSIKSNIGHAQAAAGVAGVMKVVLSMRH
GVLPQSIHIAEPTPHVDWSAGEVALLTEQRAWPETGDRPWRAGVSSFGFSGTNAHVIIER
APAEQGFEDPGAQGAPVPPAPHPLLATPTPQENGSAHRAPLPWPLTAKTEKALHAQADRL
LNHLATRPDLRSSDIGHSLATTRTAHERRAVVIGGNREEHLAGLATLAAGGTAPLFVQGA
VIGGKTAFVFPGQGSQWVGMAEALLDASPVFATRVEECAKALEPFTDWSLVDVLRAADGA
PSLDRVDVVQPALFAVMVSLAEVWRAAGVRPGAVIGHSQGEIAAACVAGILSLEDAARVV
ALRSQAIGRVLAGLGGMVSVPLAAAEVRERIAAWGEERISVAAVNGPSSVVVSGEVQALE
EFLAACERDGVRAKRIAVDYASHSAQVELLREELDTLLAPIAPRAAGVPFLSTVTGEWVE
GPELDAGYWFRNLRRTVELERATRTLLDQGFGVFIESSPHPVLTVGLQETVEDAGREAAV
LGSLRRGEGGLERFWLSLGEAYVRGVTVDWDAVFAGTGAQRVDLPTYAFQSQRFWPEAAP
VDAEAPSAENALDARFWDAVEREDLAALTAELHIEDGQPLTALLPALSSWRRESREQSTA
DGWRYRVTWKALAEAAPTRLSGTWLVAVPETLTGPAGDTAAAVLRTLAERGAEVRTLTIA
AGAAHRDALTAAIEAATGEDTAPEGVLSLLALADSDGAALREHTGLLHTAALVQALGDAH
VSAPLWCLTRGAVSVARSERLQDPAQALLWGFGRTAALEFPDRWGGLLDLPAQADDRTLE
RLVGVLAGDGSEDQVALRPSGLFGRRLVHASLADAPLAPAWKPRGTTLVTGGTGALGAHV
ARWLAENGAEHLILTSRRGDGAPGAATLREELAVLGARVTISACDMADRDAVAALLASVP
AEQPLTAVVHTAGVLDDGVIDGLTPQRFATVLAPKADAALTLHELTRDLDLSAFVLFSGV
AGTLGDAGQGNYAAANSYLDALAEQRYADGLPATSVAWGRWGDSGLAAGGAIGERLDRGG
VPAMAPRSAIRALQQALDHADPAVAVADIQWERFAPGYTAVRPSPFLGDLPEVRRIAQAA
PAAGDGDAGAPGAPGEALRRRLTVMPQTEQALAVLELVRTHAATALGHAGTDEVGAGRAF
KELGFDSLIALELRNRLNAATGLKLPATLVFDHPTPAVLADFLRAEIVQDGSAAAAPGIA
ELEKLESALSVLDPDGGTRADIASRLQALLAKWGEPQAHSSGEAVADKLQEATPDELFDF
IENELGI
>A0A221W4X7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinoalloteichus hoggarensis|TrEMBL
MTTSTEELVEALRASLKENGRLQRRVRELSDAAGEPIAILATSCRYPGGVDSPERLWQLV
RDGTDAMGDFPTDRGWRERGIGGFVHDAGDFDPGFFGISPREALAMDPQQRLVLQTSWEL
LERAGIDPTTLAGSRTGVFLGAATSGYGAGLAETPAEVAGHLLTGSAGSVVSGRIAYLLG
LEGPAVSLDTACSSSLVALHLAARALRAGECSLALVGGVTIMASPMAFQEFGRQGGLAAD
GRCKPFAEAADGTGWSEGVGMLLVQRLSDARREGRTVLAVVRGTAVNSDGASNGLTAPNG
PSQQRVIRAALADADLRPSEVDVVEAHGTGTALGDPIEAQALLATYGRDRPAERPLWLGS
VKSNLGHTQLAAGVAGMIKMVEAFRHRVLPRTLHVDRPSTQVDWTTGAVRLLTEEQAWPV
ADRPRRAGVSSFGISGTNAHVLLEEAPAEHPPRPAGSAAPGDAAMPAHSAAPGDVAIPDA
SDASATPGGSHTGAAPAVPAGVLTGSAQPPAIVGWPLSARSSEALPAQAARLLAAQSSHQ
TVQDSPTSDGTAPLADVGWSLATTRAAHHHRAVVLGADRPTLLRGLAALAEGTAEARVIT
GTRLTGRTAFLFSGQGAQRHGMGRALHAAHPAFAAAFDDVCAGFEGTLDPPLRDVVFAED
GTEAAALLHRTDYTQAGLFAVEVALFRLLESWGLSPDVVTGHSIGEVAAAHAAGVLSLES
ACLLVAARGGLMRDLPGGGAMLSVAATEDEVRPLLTETVDLAAVNGPASVVLSGDEDAVL
ELGARFEALGRRTRRLTVSHAFHSPHMTPMLAEFRAVAESIDYAAPTIPLVSNLADADPT
SPEHWVRHVREPVRFHDGLTALRGREVVRFLEVGPRGVLTALAGESRAGDEALIPALRGG
QDEPAALAAAVARLHTAGRSPDWDAVFPDARPVDLPTYAFTRTRFWLADPTSGDEDSARY
EVGWTELDESTDLAPAGSAGRWLVLVPEALAADEYPAAVRATLAEAVGEVDVQPVDVRGL
RRDGLAGLLRAAAEDVPPAGVLSLLSWSAPGGEAEESSCPVTVAVLLLQAVADAAIEAPV
WLVTRGAVGIGDHDPVAAPAQAAVWGLGRVAALEFPRDWGGLIDLPSAVDRRAVGRLPGV
LLGDAGEDQVALRAAAGHGRRLRRIVEPVQAQSWPSRGTALITGGTGALGGHVARRLAET
GTEHLVLLSRRGPAAPGAAELERELHALGVRVTMPVCDVADRAALATVVRDLDEAGEDLR
TVVHTAGVAGFGALRDTSVEEVANILRAKVAGADNLHAVLGDRDLDAFVLFSSIAGVWGS
GGQAAYSAANAHLDALASHRRAAGLAATAIAWGPWGEGGMVADDEAAQALRRVGLLLLTP
ATAIAALEASLVEDRATTTVAHVDWSVFAPGFTALRPSPLLGELAEARAALDVAADPTGD
GGADLRARLAATEAAERGALLLTLVRTEVSAVLGHDTPDAVEPDRAFRDLGFDSLTAVEL
RDRLVSATGLSLPTTLVFDHPTAADLADRLRAELLDERDSDEPLAMLTPLDRLENGTARF
SAADIETTGIVDRLQALLARLDAVRRGSADPDGLPDDAPDSVGDRLHAASADELLAFIDD
EFGTASATKDQ
>A0A4R8SJN8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides salmoniphilum|TrEMBL
MESADHPIKPAPRFAIIGYAARFPGAANADEFWDVLREGRDAISEVPADRWDADEFFDPE
PGAPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRLMDPQHRLLLEMAWRAVEHSGIAPTD
LAETNAGVFVGLATHDYLGMASDELTFPEIEAYMAIGTSNAAAAGRISYRLGLQGPSVAV
DTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSHAHMLAPDGKCKTFDA
AADGYVRGEGSGVIVIKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
DALKRAGVAPSDVGYLEAHGTGTSLGDPIEAQAAGAAYGIGREANDPLLIGSAKTNIGHL
EAAAGIAGVIKVILSLENELLPQHRNFQNPSPHIPWDRLPVEIVKEATAWERNARPRIAG
VSSFGFAGTNAHVILEEAPEQAAAPVETDTPGEPQSTGSLFSILPLSARTPAALVQIADQ
YRSWLNAHPEATLADVCLTAGVARAHLEHRAALVVNSREAAVELLGAVADDRPAPGLGRG
ESYEAPKTAWLFTGQGSQYPGMARELFDTEPVFAETLKHCAAVVADVLEKPLLDVIFDVD
SPEAGEALRQTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAGVFSLED
GARLMAERGRLFGSLPAGGRMAAVFAAAERVESLTDEFPSLSVAAYNGANTVLSGPAQDL
EKAVAGLVAEGVRCDFLETSHAFHSALLDPILDEFESYAGQFNYKTPQRILIDNRTGAAL
GRSTKLDGAYWRRHARQPVEFAKSVRTLADLNCKVLLEIGPQPVLTAAALRAWPDPATAP
RAIASLRRNTADHRQITEAAADAYVLGHVPNFGAFRHGHARKLDLPTYPFEHRQYWFSDK
RDADGRDTTNQQQRAGGPRTEAVRLLEDGKIEELANLLGGAGGDQQTLAVLTKLAAQHNQ
QRTTQTIADDRYQFRWDKSPTPLSGTESGAGISWILVGEVSGAAAPLVEALTARGHQHRI
LGLPASDADEQQLADALRAEAADASAQGQTLRIVHVAALDAGSPSARSLLRIQHQVLAGT
RRLFRAAAAAELRAPIWLLTRGAQRIIDADTVAPEQSALWGFGRAAALELPQVWGGLADL
ADASADEWSQFIARASASTDAAAREDQIALRDHAVYVPRLVRREELPSGRPLEVRDNATY
LVTGGLGSIGLEIAGYLAAHGAKNLVLTSRREPNESARQRIDALGAQHGCEIRVVTADVA
DAHDVARLLAGVQAELPPLAGIVHAAGEIGTTPLSDLDDAEVDRVFAGKVWGAWHLSEAA
ADLKLDFFISTSSIASIWGGFGQTAYSAANAFLDGLAWRLREQGIAGTSVNFGPWSAGMA
DAESRARLEQRGIKTLSPADALAGLADVVSASSPQGVIARIDWARFLPLYQQAGRRAFLA
ELEREVPSHLAASPVVTSSGKTQLVERLASAPIQQRKKLLTDYLRDAVAEVTRVDVSEIR
EDAGFFDLGMDSLMAVELRRRMEQGVGKEIPVTLVMDHPRISDVADYLLGEVLGLNEQVK
SAPRQAATTRTDEPIAIVAVSCRFPGAPDPEAFWDLLSGGVDAIREVPEDRYDIDEFYDP
DPEVAGKTYTRFGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYSPA
ALRGSRTGIFAGVGANEYAHLLSSESLDKIEPYFITGNALNAISGRVAFALGFEGPAVAV
DTACSSALVAVHQAVQALHSGDCDLAVAGGVNVLLSPVTVIAASRARMLSPVGRCKTFDA
SADGYVRSEGCGILVLKRLSDAQRDEDRILAVIPGSAVNQDGASSGLTVPNGGAQQRLIG
TVLDRAGLVGGDVDYLEAHGTGTPLGDPIEVQAAAAAYGGSRDADRPLLMGSVKSNIGHT
ESASGAAGLIKVVLSLQNGVLPQSLHFEKPSPHIPWDSLSVRVVDKAIPWEANGRPRRAG
VSSFGFTGTNAHVLIEEAPQRPTDVEEGASDVPDVAPEPQGDQVSVLPLSARSPEALAAV
AQRYESWLSAHPDVDIEDVCLTAGRGRSHFEHRAALVVDSVESAREGLAELVQNRLRPGV
VRGEHTNHPTTAWLFTGQGSQYPGMARELFEAEPVFAETVTRCAEAVKDIVTRPLLEVMF
ATDRETGGEAGKALRHTSFAQPAIFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAG
VFSLEDGVRLIAERGRLFGSLPAGGRMVAVFSDAKHVEQIAGDFPRVSIGAYNGPNTVLS
GPGEDVEQAVARFEGEGIRCTWLETSHAFHSELLDPVLDEFESYAAQVQFATPTLPLVCN
RTGAVLTAQTPIDAQYWRRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWP
EHLAAPRAIVSLRKGVGDRRQIAEALAAAYVGGHRPNFAALQRHPRNTLELPTYPFQRRR
FWPKSSGAAVNGGVGGATAGILGRGEDLASGDSVYISRLSVRSQPWLSDHVIYGTVVVPG
ATYAAMALAAVGTPARAKDVFFYEPIILPEKSSREVQLTLHPLEDGSGSKFQVHSRPYGE
RDVDWSLNAEGTVVTGIGEDPDEPTSEASEPIDAAIERMERMRPMELFEIFADLELSWGP
TWSGSLKSLWLGEGEAIGDVLVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQG
INDLFLPLRYGQVTLKEKMPRRFYCRARWHESPLDSETQVFDLDYLDRDGRHLGGIREFT
VKRAPREALLRGLGGDATRLLYTLGWHEVPVPPSEDAAVETSGTWLIAGFDELAAKVPGC
IPFDRTTNPELLGQVLEQAKERGVPFSGVVWRAAEPSATEGAGFSDTEIARLEAEIANLL
SAVHTVQNGSQNGVKLPHGLWIITERAVATESGEPVDPVQASLWGFGRTTINEEPALRAK
LVDCDGSPEAVQALANLLVTPVDEPEIAVRQGKLLASRLLPWSRSGNLTVPRGSDYALLP
TERGAIDNLRIIEKEVPAPDDGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGVV
TQLGEGVTEVAVGQRVYGSMQGAFASRFNAPAQFLAPIPDGVSAVEAATIPAAALTVRLA
FDWAQLKPGDRVLIHAASGGVGLAAIQMAQQQGAEVYATASTFKRATVRKLGVKYVYDSR
TTDFADQILADTDGAGVDVVLNSLTSEGFVEATVRATAKNGRFAEIAKRDIWTPEQMAEV
RPDIAYEIVALDTVMFQEPERIRALLTEVSEGLGKGEWTPLPAEIYPLTEARTAFRRMQQ
ARHIGKIVCQMPNPLAPRSDRTYLITGGLGAIGLHTAGYLAQLGAGDIVLTSRRAPDTDA
QRLIEEITERSKTRIHVFTADVGEESEVAQLLERIRAELPPLAGIAHLAGVLDDALLGQQ
SVERFRTTLAPKAFGAGYLDKLTQGDELDFFIVSSSVSSLFGSPGQSNYATANALLDGLI
AQRRAQGLPATGVNFGPWGQGGMASSEAATANISAQGLIPLDPSAALAALAEVIANGTGQ
ATVIKANWQRAAKVLGSSRPPILDLVLPSAVGEVTGDSELLKQLMEIPVPQRAGFVTEFL
QREVQNFLRLAQPPAATSRFLDLGTDSLMAIELRNRLHSQFGGKFTINATAVFDYPTIGG
LAEYLVAQLPDAKSESEEAQPAVESAEAESDAAPTPSDAVSEPKE
>A0A161UFH7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudovibrio sp. W74|TrEMBL
MLEIVGLSVRVPGASSKEELWNLLCSKRNSISEIPADRWSHFRYLHPRISEPGKAYTFKA
GVLDNLWDFDPTAFGISPREAEQMDPQQRILLQLTWEAIEDAGISPDTIAGDHVGVYVGA
SALDYANESLFDPNVATGHFMTGNTLSIISNRLSYIFDLKGPSFTVDTACSSSLVALHEA
YRALNSGRIDCAIVAGVNVLASPFPFVGFAQATMLSPDGQCKAFDAGGNGYVRSEGGVAL
VIKRKDAPRWKGQRSHADIVAVDVNSDGRTVGMSLPSDVEQANLLDRVYKAHGIDPNQLA
FVEAHGTGTRVGDPAEAGSIGRTIAQKRRAPLPIGSVKTNVGHLEPASGLVGLAKSVLAL
QNDHFPASLHFNEPNPDIDFDALNIHVASEGVELPRSESPRYAGVNSFGFGGTNAHVILK
DPEFKTDNVEQLTQPKTVSSLFLSAPTKEALVELASGYARDGALTEQSNHKICAAAFHRK
RIFPEKAVFSGTDVEILKATLSDFASGQKNANVIYSNKATNPGKCAFAFSGNGAQWAGMG
RDAYVANQTFKIAFEKVDELFTNLSGWSLKTELFSETLDDALKRTNIAQPLLFAVQVALC
QALEDYALKPDMVLGHSIGEVAAAHVAGALTLDAAVALVYHRSAEQEVVAGHGTMAALVL
PADEARQLISKSGFDSLEVAAENSPKSVSLSGTKEDIDGFAKFARANHVAFRKVALNYPF
HSQLIDPVEHPFRNAVGTVTATSAQVPFISTVYGAISDGKDLNADYWWRNLRKPVLFSKA
VATALDLGAETIIEIGPKPILQSYLRQVAAEKGGKGSVLSSLSNEQFGGTDPIINLVARA
FVAGINVDTDKLFGKNPDEPVNLLPLPWQNKSYRFENSGEANMGIFRGGDHPLLGWRPNA
IYNVWTTHLDRFTVPFLEDHVINGQMIFPGAGYVEMALAAGSALYGSVAVELRSMDILQA
LVLSDEYLTEVQTEISEETGTVKISSRMRLSGDDWTLHAVGRVAKLETPAPNIQLNFEAA
QLINTGEEIYKAALTYGLEFGPRFQRTQNVSQVDEGTFIVHLSALEHDELVSSFGIHPAE
LDGCFHGLLSLFKETTSQNSRPKAYVPIFFDKIRQYQTGASPAYVRIQVKRASELSILAD
FQIFDEDDNVIIAISGGRFRATELGRKDNPSDLIYRVEAELQRNPATTVAKLNHSFPAIE
DYVAEKFRTVEDEAEREAYLLLNAAAQRTAFDIISKFADGEQTVSVEDLPNNHRRYFVTL
LTILQEAGAATECGINRFELNSDFELPDFDLLVESVLEESPQDIAAATILATTRKFVLDS
LDLDSFEDNGFEHSSAMLEQYWYSSPEAQIRSQSISEWLRTALGNWDTDTPLHVLDLSGS
GLNLAKDIQQILPSQVTKVSIADSNHKSAARLSASVLDEPNIAVFDTSNLDSNHTWDAAL
EQGPFDVIVSSGLLHEACQSEANLFEKLGQSLSGGGQFLAIEPLSDVFHDVAFGLSEDWF
AGSISDEYPVGPLKTSNDWLDQFTSTSFNAPIAIEALKEGASIVLLNATTKPVDVSQQLD
PTADLPESKAMVILAGNSKLEQEIAKAIQSDERLAACNIKLLDADSGQFDLNEASGWKSA
LAGSAFLDAELKTIIHLYGLAEAGDAPVDQVMKRCATCVGLVKAYPGLAGQLALVAPGGS
GHNAELEAPAQSAAWTFARVLGNEAPELTPLTLDVCIEKGVEGIASDILEAVLYQNIENE
LHQPQKSRVVSRVKSGFGQSTWKPAENVELNFSEAGSLNHLNWRGQQRTEPSEDHVEIKV
AATGLNFRDVMWTLGMLPEEALEDGYGGPNLGLEISGTVTRTGENAGDLSVGDKVVAFTS
GGYSSYVTCPKFAVAKLDQSQDLVSAATYPVAFLTAYYSLIHLGELKEDQWVLIHGGAGG
VGLAALQIAKHVGAKVIATAGSEEKREILRLLGADHILDSRSLQFPDKVMKLTDGKGVHS
VLNSLAGEAMEASINIVRPFGRFLELGKRDYYANTKIGLRPFRRNVSYFGIDLDQILLHD
SDLARKLIEDVFELIKDGTFTPLPHRVFEGRNVQDAFRLMQRSGHIGKILITPPKPEEVK
VPQEHTSLKFAQDGHHVVIGGLGGFGLEICRWLADNGARRITLTSRSAKVSEQHEKLFEA
LAEKGVTVSAVSCDVTDRTAVHGLLSELRQSAPLKSITHAAMVLDDGIIQQLDEKRFRKV
LEPKIQGASLLDELTRQDELDQFILFSSATTLIGNPGQSHYVAANGYLEGLARARRKAGK
PAIAVGWGAIGDVGFLARNAEVSDKLSRHLGEATIKAREGLDILKLAMEQDDGSAPGAVV
HIGRFAWAAAHQSLSLLSKPLFREIVGRSDTDGDSDGATDILSLIEGKSDTEAKEIVAHI
LAGEIGRILRLPAEDISHQRPLAEFGMDSLMGLELRMGIQKRFNLEIPLVSISGGTCLDD
FAAQILQKLRKREGGEASAEDGSHNVLASQHLSDDLDDAQKSTVREILDTHQDKTARLLN
>A0A1Q2Z2D6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MPLTYGYERFGGPEVERFAEVPRPVPGAGDLLIAVRAAGVNPVDHKRRSGRLPAGAPAVA
LPAVMGGEAAGEVVAVGAGVAGFAVGDAVLGGPTTGGFAQYALLPARAAVRKPAEVSWVD
AACLPIAGATGYAAVRRLGLSAGATLLITGVAGGVGVVAAQVAVGLGVNVVGVAGPDKRA
FVEGLGVRFVASGTGLAAAVPGGVDGVLDLVGGEVLRESAGLVADRKRLASGADREAVAA
LGGSALGPVRDPAILEAVVELVRTGALDPKVTSIVPFARAATAVRAVESGHGRGKTVLEM
SGVPLDPSLSRARN
>A0A654ZIR7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MASSGFAARLAGRSADEQLAAAIEVVCEHAAAVLGRDGAAGLDAGQAFADSGFNSLSAVE
LRNRLTAVTAVTLPATAIFDHPTPTELAQYLITQIDGHGSSAAAAANPAERIDALTDLFL
QACDAGRDADGWKMVALASNTRERMSSPVRNNVSKNVALLADGISDVVVICIPTLTVLSD
QREYRDIANAMTGRHSVYSLTLPGFDSSDALPQNADMIVETVSNAIIDVVGGSCRFVLSG
YSSGGVLAYALCSHLSVKHQRNPLGVALIDTYLPSQIANPSMNEGFSPNDTGKGLSREVI
RVARMLNRLTATRLTAAATYAAIFQAWEPGRSMAPVLNIVAKDRIATVENLREERINRWR
TAAAEAAYSVAEVPGDHFGMMSTSSEAIATEIHDWISGLVRGPHP
>A0A853SNA9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Janthinobacterium lividum|TrEMBL
MPMLGVCRDLGIFSAMEKGPVSVRQISDDLSANAGYCGLVFRALHALGCIESTDREVYTL
SERFRRGWNVPALIEDIYRIDFGAYLWNGAEVERLDHWLIASARGWNTSDTELGNLMDGA
IMVPLLLALAQKGIGQESSSSGALAPHVHLHVQPQLQAYLAAKDMLEHGASFTLNERGLY
LCERALTMASTASYRPMLLGLRELLCGDPSRVLGRDADGHETHVDRTLNVIGSGFQHNKY
FKDLAELVVAIFDSEPLEEQPRYIIDMGCGDGALLKTLYSAIAEHSLRGRHLEKYPLLLI
GADFNEKSLQAAARTLDGLPHLVLKGDIAKPQTLLDDLKAHGVTDADAMLHVRSFLDHDR
PLHVQPDVADAHPRDDLIYVNAAGDRIGSVAITRDLREHLARWSGILGRHGLILLEVFSL
PVDLTREYFSQTECFHFDFYHAMSRQALVGAGTFHQALASAGLYPNRESLVRYPSTMPFS
RIVLQHVQSKPFAVRPLRLDDVPDLLAIDRACWPENLRLTVGEIERRHAMFPEGQFVVEY
EQRVVGVLYTQRIDDLERILASQYTDYLNAHVDQGHYWQLLGLSMHPDYQSLALGDQLLE
HVLDMAALTAGVEAVYGITRCLSFRAQSESMANYVQRKDEQGLPVDPLPRFHCSHGATIE
QIVPGARPEDIENDGAGVLIRYDLATRLRGSRGGGSVAPVGECREGTLETVARAVRRVMK
TPEDFATDRPLKELGLDSMGLMELRLLLNQAFGIEFDPAYFFNYTTAKAIAGFIAGLGKA
ADVGVPVTEASQTESGAAPTDPAHCAASDIAIVGMALRFPGGIDTPEAFWQLLADQGCVI
TRRPSERWREYRSELDGLDVQYQHIHQGGFLDNIDQFDAAFFHITPLEAQALDPQQRLLL
ELAWEAMEHAGIDPHGLAGQPVGIFLGANSHDYETLTIRQRALGNLDAHFAVGNALATAA
GRLAYFFDSRGPTMTVDTACSSASSAIFAACHSLADGGAELAVAGSVNMMITPTLSVAYA
KAGMLSPDGLCKTFDSTANGYVRSEGGAVLLLKRLDDALRDGDHIHAVIKSVALMQDGRT
NGLTAPNGQAQVDVIRRALTLADRTAVEVDFVEAHGTGTYLGDPVEMQALRKVYCDDIPR
AAPLCVGSVKTNLGHTEAVSGMAGILKVVLALRHESIPAHLHLEQLNEFLKLTDGSIEVP
RHARPWKAVPGRPRLAGVSSFGFSGSNTHMLIEEFASPQVSAGASGGLLPAVVSAKSRQS
LRNNLTALARYVESQGEGLDLAALSRTLTRGRAQHTFRVAFPFGSKEQLQARLSQAMRDD
GNPDAGRKPRIAFMFTGQGAQYHGMARRLTESSPSFRRHLEHCAARVREHAGFDLFDVMW
GVDRASIDQTRYTQVALFCVGYSLAEMLREAGIVAEVVMGHSVGEFAAACYAGAMSLDAG
ISLLCHRGALMHEQTRGGSMVALLAPRTEVEDLLRGYDQVTIAAMNGPRSQVIAGDPGQV
ADIVRHAEQRNIPAIALPVERAFHSPLMAPILSQFQHLADRLDYAAPGLDLISNVTGEVW
SQSLTGQYWTDHIGSPVRFEQSVRTLLARGVDMVVEIGPRPVLTGMAMAVTQDTSVRWLP
SLLDANSHGLAALYTQASQFGVDVDWRCYPHQSVSMLPDLPRYQFDRVAHWIGPAANEVP
PKQVPSVPQTDPEQMQALAVANFVQRLDPVSDAALWAHVIVRQSVFPAGGYVALAIEAGL
RLFKRSRGVVLHQLRLERILWLEQGQAYRMEVSALPTSSSALTLQLRARPESGGKWTPYA
QAVVEALDDISPDGGGMLAPDSIGGSMVFHGDDFYTRLAALGYGYLPPFQGLHAVRRVGD
SVIAELRFKDDAPATGFAATPWGLDGCFQTVLAVLLEELEADGERMILPVAMARLAWYAP
LTNALRVTCRCRATDSGFDADLRIYDANGTLCIEIDGLACAWVRRRNLDPGSADASTPPI
YAPIWREYTEPVALAGGTGGSWLILCDERGMGAALAETIIENGGQVAQVLLADLPADASA
EAVLADLLAHHADSSTEPIGLIHAWPIDIDVQAGAAARRRALDLVVTKFLAALPDGRLNR
AIMLTCMAQPVRQSDLVVQEDAASLWGLVSALQAEASGHMVTLIDLEEVPPGAAGRRLAT
YILQTPARAFDVDAAGWPEHFALRDERWYVRQLAPVKTVVPARVAGDGCYIVSGGLGGIG
RLVAEFLHAQGAARVLLLGRHVPAVAPAWVQALNRRRDCVEVVVCDITDRAQVAEMLGKA
TRGLTIRGIVHAAGVIDDALLAAQDSGRMQKVYAPKVDGARHLLESVAGDTLDFAWLFSS
LVGLYGGSGQANYAAANAALDGYAHWMRSRGVRAMSINWGPWRDTGMAARLARPEGIMGR
MFTDALKPEDSAVLFGALLAVDAAQCCVTPWRQDLIASAMRLPYLLHTLRDPGGKAYAPP
HLADLLTGALGDERKLRTRVFVAGQIARITGLTAAAIDPSVPLSTLGMDSLMSLDLQRAL
STGLGKPLAETLLFDHPTLDALVAHVLAQAGPVFGGDVGTADVAYADSTSKLHVAMDLEL
AEIENLPDEDLGALLGKEFVNE
>K9XTR6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Stanieria cyanosphaera (strain ATCC 29371 / PCC 7437)|TrEMBL
MTDNLSPTKRALLALKQMQAKLEALENAKSEEIAIIGMGCRFPGGVNSPESFWQLLCSGT
DAITEVPPQHWQIDSYYPKQICSRKGGFVPNLKEFDAQFFRIAPREAISLDPQQRLLLEV
SWEALENAAIAPDSLSGSATGVFIGICSIDYWHQLLSRNNTEIDAYLTTGNTHSVAAGRL
SYTLGLTGPAIAVDTACSSSLVAVHLACQSLRNRECDLALAGGVNRLISPEISINFSQAK
MLSPTGFCHSFDAKADGFVRSEGCGVIVLKRLSDAISSGDQILAVISGSAVNQDGRTSGL
TAPNGLSQQAVIRQALAKSQIEPSQIDYLETHGTGTALGDPIEVNALGEVFNKREKPLIL
GSVKTNIGHTEAAAGIASLIKVVLSFQQQKIPANLHFQQPNHQINWHELPIQVATEMMPW
LNTNKPRMAGVSAFGFSGTNAHVVIQESVNRSRDVTCYVSTKGESQKALCQLFVLSAKSD
RALKDLVQRYLEFFKSNHDLSLEDVCFTASVGRSHFNHRLAVMAISIQELERKLTAFLRE
ELQSGVWSGKFTKKVDNNVIKLNPIEFTTEASLVEIAQLYVSGKTLDWFSFYQNSDYSKV
ALPTYPFQRQTYWYQ
>A0A3S4VMN6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium aurum|TrEMBL
MTSVDGLNEPTPRFAIVGYAARFPGASDADEFWDLLREGRDAISEVPGDRWDVDEFFDPE
PGTPGKVVTRRAGFVDDVTGFDAPFFGMSTREVRMMDPQHRLLLETAWRAVEHSGTAPSA
LAGTNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV
DTACSSSLVAIHQACQALQLGECDLALAGGANVLLTPATMITFSNAQMLAPDGKCKTFDA
AADGYVRGEGCGVIVVKRLEDAIRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIG
DALHRAGLRPSDVGYLEAHGTGTSLGDPIEAQAAGAAYGPGRDAGRPLLIGSAKTNIGHL
EAAAGIAGVIKVVLSLEHQALPKHLHFENPSPHIPWDRLPVQIVTETIPWERSDRPRIAG
VSSFGFAGTNAHVLVEEAPLQAPVADVAAAVGGRFSVLPVSARTPSALVHLADQYRSWLT
AHPEASLADVCSTAGVGRAHLEQRAALVVDTPESAIELLGALADDRPAPGVVRGESHDIP
KTAWLFTGQGSQYPGMARELYDTEPVFAETVDRCADVVADVLEKPLLDVIFDVDSPGGDE
ALRLTSYAQPALFAVEMGLARLWQSWGFEPDVVLGHSVGQYAAACVAGVFSLEDGALLMA
HRGRLFASLPAGGRMVAVSTAAERVESLTDDFPSLSVAAYNGANTVLSGPTADLEKAVAG
LAADGVRCDWLDTSHAFHSALLDPILDEFESYASRFTFAAPQRILIDNRTGDALGRSVKL
DAPYWRRHARQPVEFAKSVRTLAGLNCKVLLEIGPQPVLTAAALKAWPDPSTAPRAIASM
RRTTADHRQIIEAVADAYVLGHLPRFDALRQANARTLDLPTYPFEHRQYWFNDSSAAGAP
KQVTGPRTEAMRLLEDGRIEELAVLLDGADGDRQTVDVLNKLAAQHNQQRTTQSIADDRY
EFHWEKSPALTSGADAGSGWILIGDDPDAVAPLVEELTGRGHRHRLVGLPMSDADEAQLA
DELRTAAADDPQLRVVHVAALGSDTTPSMRSLLRMQHRILGGTRRLLRAAAAAELRNSVW
VVTRGAQRATDTDSVSPEQSCLWGFGRAAALELPFVWGGLADVASGSADEWTEFVNRITA
PDSTVREDQLALRGDAVYVPRLVRRATQPSAAPLYLRDDATYLVTGGLGSIGLEIAGYLA
SHGARHLVLTSRRAPGDAAQQRIDALGAQHGCEVRVVTADVADAHAVARLLAVVRAELPP
LAGIVHAAGEIGTTPLSTLDDAEVDRVFAGKVWGAWHLSEAALDTSAGTLDFFLCTSSIA
SVWGGFGQTAYGAANAFLDGLAWRLREQGIPGISVGFGPWSAGMADAESRARLEKRGVRT
LSPADALAGLADVVAAGADRGPAHGVVARIDWSRFLPLYQQAGRRAFLTELEREVPDAAL
PAVSPSGTTPLVERLTTAPVQQRRKLLTDYLRDTVATVTRVDVAEIREDAGFFDLGMDSL
MAVELRRHIENGVGAEIPVTLAMDHPRVSDVADYLLGEVLGLSEQTSDTSGLRLATAVTT
RTDEPIAIVAVSCRFPGASSPEAFWDVLAGGVDAIREVPEDRYDIDEFYDPDPDAPGKTY
TRSGGFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGIERAGYAPSALRGSRTGV
FVGVAANEYAHLLSAEPIDKIAPHFITGNALNAISGRVAFALGLEGPAVAVDTACSSALV
AVHQACQALRSGDADLALAGGVNALLSPVTVVAASRARMLSADGRCKTFDASADGYVRSE
GCGILVLKRLSDAVRDGDQVRAVIPSSAVNQDGASSGLTVPNGGAQQRLIATVLARAGLS
GGEVDYLEAHGTGTPLGDPIEVQAAAAAYGGSRAADRPLLMGSVKTNIGHTESASGAAGL
IKVVLALQHGLLPKSLHFDTPSPHIPWDSLPVKVVDEAMPWQANGRPRRAGVSSFGFTGT
NAHVLIEEAPPQPPLTEDAGSTTPTTEPDTGDRSVDVLALSARSPEALTALARRYETWLA
AHPDADLAEVCLTAGTGRSHFDHRAALVVESVQGAREALADLTENRLRTGIVRGEHTHHP
TTAWLFTGQGSQYPGMARELFDSEPVFAETVTRCAEAVADILPRPLLEVLFATDRAAGDR
ESLRHTSFAQPALFAIEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSLEDGARLM
AQRGRLFGSLPDGGRMVAVFTDAKNVEEVAAEFPRVSVGAYNGPNTVLSGPGEDLEQIVD
RFGDDGIRCTWLQTSHAFHSELLDPVLDEFESFAAQLHYAVPTLPLVCNRTGAVLTAQTP
LDAQYWRRHSRQPVQFAESVRTVAALGCSVLVEIGPQPVLTGAAVQVWPEHLAPPRAIVS
LRKGVADRRQIADALAAAYVGGHLPDFAALHRPSTRRLELPTYPFQRRRFWPKTAGITAE
GGVGPATSGILGSAKDLASGDSVYTSRLSVKSQPWLSDHVIYGTVVVPGATYAAMALAAV
GTPARAKEVFFYEPIILPEKASREVQLTLHPLDDGSGSTFTVHSRPYGDRSADWSLNAEG
TVLSGADAEEPESGPSGPSRTSMPTAPSDPVDEAIERLTRMRPQELFETFADMELAWGPT
WSGSLKSLWLGEGEAIGDIVVGEELAEQLGTEPMHPVLMDLCTGVAFPAFPALLAAEQGV
SDLFLPLRYGQVTLREKMPRRFYCRATWHTNALDGETQVFDLDFVDRDGRALGGIREFTV
KRAPREALLRGLGGDATRLLYSLGWHEVPSLPDDAAAVAAGTWLIAGFDELAATVPGCIP
FDRATDPTPLGELLGQAHERGLPFSGVVWRAAGRRPDESTADAAARLESEIAHLLSAVHC
VQRGDLKLPGGLWIVTEKAVATESGEPVDPVQAALWGFGRTTINEEPALRCKLVDCDGSP
EAVRALATLLATSVDEPELALRQGKLLASRLVPWARTGHLTVPRGGDFVLAPTERGAIDN
LRLTEADVAAPGAGYVQVRVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGVVTQVGEGVT
GLEVGRRVYGSMQGAFASRFNVPAEFLAPIPDGVSAVEAATIPAAALTVRLSFDWAQLKP
GDKVLIHAASGGVGLAAVQMAQQFGAEVFATASTFKRATLRGLGVKYVYDSRTTDFADQI
LADTDGAGVDVVLNSLTGEGFIEATLKATAQNGRFAEIAKRDIWSTEQMAEARPDIDYEI
VALDTVMFTEPERIRELLTEVSEGLAKREWTPLPAEIYPLTEARAAFRRMQQARHIGKIV
VQIPNPLQPRADRSYLITGGLGAIGLHTAAYLAQLGAGDIVLTSRRAADADTQQTIDDIT
ERFKCRIHVFAADVGDEPQVMTLLDRIRAELPPLAGVAHFAGVLDDALLSQQSLDRFRMT
LASKAFGAYHLDRWTADDDLDFFIVSSSVSSLFGSPGQANYSTANALLDGLVAHRRAKGL
PATGVNFGPWAQGGMASSEAAVANISAQGLIPLEPSAALAALAELVANGTGQAAVIKANW
QRAAKVLGSSRPPILDLVLPSAAGEVVGDSELLRQLQEIPVPQRAGFVTEFLQREVQNFL
RLASPPAATSRFLDLGTDSLMAIELRNRLHSQFGGAFTINATAVFDYPTIGGLAEYLVGQ
LPDAEPSGAPEPGAVEPEATPQDATAD
>A0A7X6AX69|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces malaysiensis|TrEMBL
MVNNEDKLRDYLKRATADLRQARRQLREVEERHQEPIAIVAMSCRYPGGVTTPEELWRLV
LDGQDAISGFPTDRGWDVESLYDADPDQAGASYVDEGGFLYDAGGFDPAVFGISPREAMA
MDPQQRLLLEASWEAFERAGIDPTGLRGHRTGVFAGVMYHDYTSRLDSVPEGVEGFLGTG
SSGSIASGRVSYTFGLEGPAVTVDTACSSSLVTLHMAVQALRNGECSLALAGGVTVMATP
STFTEFSRQRGLAADGRCKPFAAAADGTGWGEGVGMLLVERLSDARKNGHPVLAVVRGSA
VNQDGASNGLTAPNGPSQQRVIHQALTNGRLSAADVDAVEAHGTGTTLGDPIEAQALLAT
YGQEHTEDQPLLLGSIKSNIGHTQAAAGVAGIIKMVKAIEHGVLPRTLHIDEPTPHVDWS
AGAVSLLAETTPWPETGRPRRAAVSSFGFSGTNAHTILEQAPAEEPAEDATEAPAPAKPL
DVVPWALSGKSAAALRAQAERLLAHLEADPSLSPLDVALSLTTTRAQLDHRAVVRGQDRD
TLMAGLTALAEGGMAAGVAQGSAVGGRTAFVFPGQGSQWAGMAVGLMDASPVFAARIEEC
AGALGEFTDWSLVDVLRGVEGAPSLERVDVVQPVLFAVMVSLAELWRSLGVVPAAVIGHS
QGEIAAACVAGALSLKDAARVVALRSQAIGRVLAGKGGMVSVALPVAEVRERIESWGEER
ISVAAVNGPSSVVVSGEPEALDELIASCEADEVRARRVPVDYASHSAQVELLRDELLELL
APVRPKTAEVPFLSTVTGEWVEGPELDAEYWFTNLRRTVELEGAVRRLLDEGFGAFIESS
AHPVLTMGVQETAEDAGREAAAIGSLRRDEGGLDRFWASVGEAWTRGVTVDWDGVFDGTG
ARRVELPTYAFQHQHYWLESGTPTADATPAADPVEARFWEAVEREDWQSLAAELDVDGDE
RVSALLPALASWRKQAREQSTVDGWRYRVTWKPLADGQPARLTGVWLVVVPGAPSATENT
DTWTDAVAGVLAERGADVRRIAVDTDADGREELTERLRAALAETDGIPFTGVLSLLALDG
HPHPRHPSVPAGVAAQLALVQALGDAEIGAPLWSATRGAVSVGRAEPLESPEQALVWGLG
RVAALEHGERWGGLVDLPGAPDERALARLVTALAGAEEEDQVAIRATGLLVRRLVRAPLA
ATPPVRTWEPTGTILVTGGTGALGAHVARWLAGNGAEHLVLTSRRGLDAPGAADLRSELT
ELGAKVTIAACDVADRAQVEALLADIPAEHPLTAVVHTAAVLDDGVIEGLTPDQVDRVLK
VKVDATRHLHELTRDLDLSAFVLFSSFAATFGAPGQGNYAPGNAFLDAFAEYRRAQGLPA
TSLAWGPWGEGGMAEGGVGDRMRRHGVIEMAPRSAVTALQHALDRDESVLTVVDMEWKRF
VLAFTSGRSRPLLHDLPEARDVIQEMAGDAEADGAGAVALAQQLAGVPEAEQERLVLELV
RTAVAAVLGYAGADDVEAGRAFKELGFDSLTAVELRNRLSSASGLKLPPTLIFDYPTPTV
LARHLRGEIAGERSAAVAALPTAAALADDEPIAIVSMSCRFPGGVRTPEELWQLLVSGGD
ALSEFPGDRGWDTEALYNPDPDAQGTSYTREGGFLTGAGEFDPTFFGISPREAMAMDPQQ
RLLLEASWEAFERAGIDPATLHGSPSGVFVGTNGSDYSILMRSNTEGYEGHLATGSAASV
VSGRLSYTFGLEGPAVTVDTACSASLVALHLAVQSLRQGECSIALAGGVTVMATPGTFIE
FSRQRGLSSDGRSKAFSADADGFSPAEGVGMLLVERLSDARKNGHPVLAIVRGSAINQDG
ASNGLTAPNGPSQQRVIRQALANARLSAAEVDVVEAHGTGTTLGDPIEAQALLATYGQER
PEGQPLLLGSIKSNIGHAQAAAGVAGVMKLVLALRHGVLPESLHIVEPTPHVDWSAGAVE
LLTEAREWPQTGRPRRAAVSSFGFSGTNAHAIIEQAPAEEPDEAEPVTRRPGALPWTVSG
KSEAALRAQAGKLLAHLDADPAPRPLDIGHALATTRAAFDRRAVLVGTDRDDFVRGLDAL
ARGQVVPNLVQGDSIGGKAAFVFPGQGSQWVGMAVELLDASPVFAARIDECAAALAEFTD
WSLVDVLREAEGAPSLERVDVVQPVLFSVMVSLAELWRSLGVRPSAVVGHSQGEIAAACV
AGILSLQDAARVVTLRSQAIGRVLAGKGGMVSVALPVAEVRERIEPWGEERISVAAVNGP
SSVVVSGEPTALDELVAACEADEVRARRVPVDYASHSAQVELLRDELMELLAPVKPKAAE
VPFLSTVTGEWVDGTELDAEYWFTNLRRTVELEGAVRRLLDEGFGVFIESSAHPVLTMGV
QETAEDAGREAAAIGSLRRDEGGLDRFWVSLGEAWTRGVSVDWEAVYEGTGAVRVELPTY
AFQHQTYWPRAADVPADESGTPSDAVDARFWEAVEREDLESLADTLAFGDDGERSSLGAV
LPALASWRKQAREQSTVDGWRYRVTWTSLTERQAPRLSGIWLLAVPESAATDDWTLGAIR
MLAERGAEVRQITPTAVESDRASLTRLVREELADAGTVSGVLSLLAFDEGTAPGTDGVNA
GLTGTAVLIQALGDAGVDAPLWCATRGAVSVGRTDTVDSPEQALVWGLGRTAALEYPERW
GGLVDLPGAPDERALARLAGVLAGSDGEDQLAVRTAGVFARRLVHAPLAGAPAARSWKPA
GTTLVTGGTGALGAHVARWLAANGAEHLVLTSRRGLEAPGAAELRDELTGLGSEVTVAAC
DVADRKAVETLLATIPADQPLTAVMHAAGVLDDGVLDALTPERFATVLGPKADAARHLHE
LTRELDLSAFVLFSGIAGTLGDAGQGNYAAANAYLDALAERRRADGLPATSVAWGRWGET
GLAADGAIGERLDRGGVPAMAPHAAITALQRALDHADTVVAVADIQWDRFAYGYTAVRPS
PLIGELPEVRRLRETGGPAAGEPGAGQDGSPAEALRKRLAGISRAEQSLVVLEVVRSGAA
AALGHSSTDEVGAGRAFKELGFDSLIALELRNRLTAATGQKLPATLVFDYPTPTALAEFL
CARIVGDGGTAAEPGVAELDALESALSVLDPDSEARETIAARLRDLAAKWAEPRTADAEA
AEGDGGTVTEKLQEATPDEVFAFIDKELGI
>A0A291SZ26|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces malaysiensis|TrEMBL
MSLPALLARRAAENPDGLAYCYLRNGEDPDDRVTYAELRRQALVRAAELRRRDMRGRGAV
LMYPTGLEFVRAWLGCTAAGVMGAPVQVPRNGQALRRLRSVADDSGTTWVLTTAETRDRL
LADFPGAPELRGLELLATDEFPETATAGEPPPAAGPDDVALLQYTSGSTGTPKGVMVTHR
NFWHNAAETDALWPTRGGTVVSWLPLFHDMGLLFGVVLPLWAGIPSYLMGPEAFVRRPAR
WLEALSRFRGTHAAAPNFAYDLCVREAPPAPGCDLSAWRAAVNGAEPVRLHTVRAFIEAF
TPYGLDPRAVSPGYGLAEHTLKISGSGPGEPPRALTLSPADLGEGRVTETTDAAAVPVVS
CGRTIGGTRVRIVDPATGRAAAPDRLGEIWATGPCVAAGYAGRERESEETFRARIADDAD
TAAFLRTGDIGFVRDGELYVTGRLKDLLVVKGRNHYPQDLEYSAERSHPALRPASAAAFA
VDRGDREALVVVIEADGRALRAAGHDVLVSAVRERVRSDHRLEAEDVVVIRRGTLPKTTS
GKVRRGTCRQQYVDGTLVRVGGGPA
>G4HYP5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium rhodesiae JS60|TrEMBL
MALTEHPTQQAPRFAIVGYAARFPGAADADQYWDLLHDGRDAVTEVPQDRWDVEEFFDPD
PDAPGKIVTRRAGFIDDATGFDAPFFGVSAREAKVMDPQHRLLLETAWQAVEHSGTAPTS
LANTRTGVFVGLATHDFLGMASDALTYPEIEAYLAIGTSSAAAAGRISYRLGLQGPAVTV
DTACSSSLVAIHQACQALRLGECDLALAGGVNVMLSPATMITFSHSRMLAPDGRCKTFDA
AADGYVRGEGCGFVTIKRLEDALRDGDHIRAVIRGSAVNSDGASGGLTVPNGVAQQRVIG
EALECAGLAPRDIGYLEAHGTGTSLGDPIEVQAAAAALGRGRDADQPLLIGSAKTNIGHL
EAAAGIAGVLKVVLALEHQELPKHLNFRNPSPHIPWDRIPVKVVDQPVAWERSERPRIAG
VSSFGFSGTNAHVILEEAPQAAPAEPAAPADDRRFMVLPLSARTPAALVQTAERYRSWLG
AHPEATLADVCLTAGAGRAHFEHRAALVVNSLESARELLGALTDDLPAPGLVRGDSVDAP
KTAWLFPGQGSQYAGMARELFETEPVFVETMTRCAEAVADVLERPLLDLIFDADGAETLK
QTRNAQPAIFAVEMGLARLWQSRGFEPDVVLGHSVGQYAAACVAGVFSLEDGARLLAERG
RLFGDLPAGGRMCAIFADPDRVERLTDEFPSLSVAAYNGANTVLSGPAADLERAVTQLTD
DGARCDWLDTSHAFHSALLDPALDAFEAYASGFEFAAPQRILVCNRTGATLGRNANLDGS
YWRRHARQPVQFAKSVATLAELGCALLLEVGPQPVLTAAALRAWPDPATAPKAVPSLRRN
GADHRQVTEALANVYVAGHLPDFAALIPHPAHKLDLPTYPFQHRQYWFNSQQIQTAANQG
AATEAVRLLEDGRIEELAALLDGPSGGSQSTAEVLSRLAAQHNLQRSAQSIADIRYEIRW
ERSKNSSPAELGEGTAWLLIGDDTAVMRPVIDVLTTNGHRHRILGLPVSDADEERLVEEL
RSAAQDEPGLRILHIAALDSDGAPSMRSLLRMQHRILGGTQRLFRAAAAAELRTPIWVST
HGAQRATDADTVAPEQSSLWGFCRAAALEYPQVWGGLVDLSGRGADEWSRLIKQVVTTSP
GEDQIALRGDAVLVPRLVRRTGQPNTTPLELRSDATYLVTGGLGSLGLEIAGYLAAHGAK
QLVLTGRRAPSEAARRRIEGFREQHGCDVRVIAADVADPHEVARLLTTVQAELPALRGVV
HAAGENNTTPLSSLDSAEVDRVFSGKVWGAWYLSEASADLQLDFFLFTSSISSVWGSYGQ
AAYSAANAFLDGLTWRLREQGVPGISVNFGPWSAGMADQDARAQLDRRGIRTLSPSDALA
GLADVMAGAGAQGPAEAVVARIDWTRFLPIYLQAGRRELLSEVAREVPESVSATTTASGT
TRLVEQLTAAPVQQRKKLVLEHLRNTVAEVTRIDASEIREEAGFFDLGMDSLMAVELRRR
LEQAVGKELPATLAMDFPRLSDVADYLLSDVLNLNERAGSQLAAQPSSLATSATDEPIAI
IAVACRFPGAPDADAYWDVLSGGVDAIREIPEDRFDVDQFYDPDQQTPGKIYTRSGGYLE
SVDGFDPEFFGISPREAVWIDPQQRLMLEISWEGLERAGYSPTSLRGSRTGVFVGVGANE
YSHLLSGESVENLEAHFITGNALNAIAGRVAFTLGLEGPAMAVDTACSSSLVAVHQASQA
LHSGDCDMAIAGGVNVLLSPASIVAASRARMLAPDGRCKTFDAAADGYVRGEGCGVLVLK
RLSDAQRDGDRVCAVIRSSAVNQDGASSGLTVPNGGAQQRLITAALTRAGLTGDDVDYLE
AHGTGTPLGDPIEVQAAAAVYGAGRDPGRPLLMGTAKTNIGHLESAAGVAGLVKVVLSLQ
HELLPQNLHFHNPSPHIPWDSLPVQVVDKPTPWYANGRPRRAGVSSFGFTGTNAHVLIEE
TPQPPVSDDAADEPVDSANAPDVLREPLSLLPLSARSAQGLTALAARYSTWLATHPEAAL
ADVCFTAGAGRSHFEHRAAVVATSGQEAKMLLDDLVANRLRPGVIRGECTDPPTTAWFFP
GQGSQYPGMARELFDTEPVFADTVRRCAQAVDPMLPTPLLDVLFSGDREAAETLRHTSFA
QPAIFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSLEDGARLIAERGRLFGS
LPAGGRMVAVFADPEYVERAATAFPRVSVGAYNGRNTVLSGPGEDLEQIVATCSEDGTRC
TWLETSHAFHSELLDPVLDEFESFATQFDYAVPSRPLVCNRTGTVLTSETPINAQYWRRH
SRQPVQFTESVRTVAALGCSVVMEIGPQPILTAAALQIWPESAATPRAIVSLRKGANAQR
QITEALATAYICGHRPDFAARYHTPGRRLELPTYPFQRRRYWPKTSGIRVDGTAASGILG
SAKDLASGDTVYTNVLSVKTQPWLAHHVIYGTVVVPGATYAAMALASAGAPARVKEVFFY
EPIILPDKASREVQLTLHPVDDGWKFQVHSRPFGVRDAEWSLNADGTLLTGAEPEAEAQD
ARVSPAEAVEQMNRIRPQELFDIFHDMELTWGPTWTTSLKSLWVGEGEAIGDIAVGDELG
EHLGIEPIHPVLLDLCTGVVFPAFPATLAAEQGMTDLFLPLRYGQVRLHEKMPRRFFCRA
RWHENAVTNETQVFDLDFVDRDGLVLGGISEFTLKRAPREALLRGLGGDSTRLLYTLGWQ
EAAAPAVEATDEAKTATGTWLIAGFDALAADVPGAATVADATDAQSWQRAFAEAAERGAP
VSGIVWHSSGHTGPDGSTTDLAARLEAEVATLLGAAQTALAEGNHSLADGLWIVTERAVA
TEPGEPVDPAQAALWGFGRTLIAEQPSLRVRLIDGDGSEESLSWLAGALGAPVTEPEMAV
RQGRFLVSRLLHWARSGQLPMPRSDDYTLAPTERGAIDNLRLSEVEVTAPDANEVQVRIE
AAGLNFRDVLNVLGLYPGDPGPIGGDLCGVVTEVGSEVTGFEVGQRVFGSMQGAFASRLN
VPAPLLATVPDDISAVDAATIPAAALTVRLAFDWAQLKPGDKVLIHAASGGVGLAAVQMA
RHQGAIVYATASKYKQETLRAMGVEHVYDSRTTDFADQILEATDGQGVDVVLNSLTNEGF
IEATVRATAQGGRFAEIAKRDIWTAEQMAELRPDINYEIVALDVTMMTNPDHIQRLMAEV
SDGLATGQWKPVPAEVYPLTEARTAFRRMQQARHIGKIVVQMPKPLQPRGDRSYLITGGL
GALGLHTATYLAQLGAGDIVLTSRRAADAEVERAIEAITERFHCRIHVFPADVGIESELA
ELLAKIRAELPPLAGVAHLAGVLDDALLPQQDLAHFQATLGPKAYGAHHLHRLTKDDALD
FFIMYSSASAVMGSPAQANYATANALLDGLVAHRRAQGLPATAVNFGPWGHGGMASSAAA
LANLSAQGMMPLEPSAALAALGEAIRHGAAHATVLKANWQRTAKMLGGIRPPLLDQVLPT
DGGVVAGDSELLRQLQETPVAQRAAFITEFLQREVQGFLRLAQPPAATSRFLDLGTDSLM
AVELRNRLFGQFGGKFDISPTAVFDYPTLGELAEHLVSQLPDSDAPSTEAEASAETEPVS
EPAPTPAPEN
>A0A086KQG0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii FOU|TrEMBL
MTPDELHTYVSNVVLDTARQVLGTSELPALDSPLQELGIDSLGAVELRNSLSQRLGVKLS
ATTLFDYPTIRAIIDYIVNQVSGEASAAKATSGALVSAGLAAGRNSPIAVVGYSCRLPQG
SETPDKLWEMLRRAQDCVVEVPLTRFDVDMFYDSDIDAKGKMYVRKACFMDDADMFDNSF
FNISAAEVTYMDPQQRVMLEVAYDAFYSAAYSREHLIGKNYGVWIGCCNSDWHFLEQQSN
PDKSSSYSGPGGSGCLVSNRLSYVFGLKGPSMTIDTACSSSLVAADCGAQAMRFGYCDGA
LIGGVNLMLSPQLFLAFCKARMLSPDCRCATFDEKANGYVRGEGAGAIMLRHLADAQREG
KRILGIVRGTAVNHDGRSASLTAPNGPAQQDVIRSALQIGGVDPLDVALVESHGTGTALG
DPIEMGAIKAVYGAGRSADSPLVVGALKSYIGHLEGSSGIAGILKVLLCLRHHEVPPNLH
FDTPNPHMDLSDFHVVLPKKQMKLQPAQKSSTILGSVSSFGFGGANAHVVFEEYPEPTMA
TDVGGERRSTEAAESAGKKRLAFLFTGQGSQYPNMCKQLYEEEPVFRSHMDACFTVLEGK
LDVKLRDVIYPTAENDVEMLNLLNQTGYSQPAIFCVEYALAQLMISKGFSPSVVMGHSLG
EYAAAAIAGVMDWKDALLLVHERASIMQHIDPNDGVMYACRASEQDAQAAVEKALGEKAV
AVTVSAINGPRSIVLAGTQPDVLAVLKAMDMQSRAKQLTVSHAFHCPLVGEAAALLLPKV
ESVKLSNPNEGITFISTVTGKAVGAGELTKPEYWATHITKPVQFLQGMRAAVTSGEAGIF
IEIGPRPTLVNMGQQCVPRNDYTWVAPVDPKDSNRNSFPQALEKITSNMVCTYTWKRHAF
PWTVVVHPFVDKFVPDQDETKATSQKLLTPAVGELLHDHVVNGTAMMPGVGFLEAMAAGG
FMMVDGKLPSTVVALRDCEFERPMLIPKIDPSTGEFTQAAKLMITVNNKDITLKSIMDGE
EEEIFHSRCTFSLCPATSLPTEPADLLTSLQGRITTPVPITTLYETLQSVGLQYGARFQS
IRECYAAASDEVLAKLRPKLPLHSFERNFRIHPVLLDGALQTAAVLFAEMGHKRPLVPVG
VKRALLARVPAGSEVWSHVVVKSKDLRSATMDVTLFSTKGTILGQLVDVAVRAFDAVAGA
QIPKGLLWEVSWVPKAKAPVEDGVDTVENEASETITPTAKLAVKPTGKVEGLARQPAVNG
QPKWLLLKTPSSMLEGLQKALQGTPSAFVKELDEKHPNNAISSKIHNSEWDAIIYLGALS
AAASSTTCVADALLLANTLGNTAAEKPLPNVLFVTQGQHFIRECGDVPTTAVPTQTGLYG
FCRSAQLELENIIGRPVYLGTLDFAAKDPTLDDPAAFVSALQRVLAEADPTGAAGTCEPH
TVIRGGKEMVPRLVKSSIECRGAVELHMSDRGALSMLKLRPMPKSARVPPPRDCVEIRVR
AVGLNFRDVLNVMGLYPGDPGPPGADCAGTVVAVGEGVEHLRVGDAVFGIAQGALKTFVT
TSAHLVRPLPGRLTFEQAAALPVVASTVEYALHDVAKVKKGDKVLIHAVTGGVGLAAVQF
CKRVGAEIYGTCSGGKKEEFARSVGVKYITSSRDPKKFAEDMCEFLGNGKHKIDVVLNCL
IENYIPETLKFLAPNGRFVELGKRGIWTREQMGTVRPDVLYETVAIDTMMEEDPVWFGGM
LDRIRNLVDGSMLQPLPLHTFEMTDSSEGGVAAFRFLQRAQHIGKVVIRLSSALEVKNFT
TNSRQETENEDSGERHTLSPATAVGKPLSQSVADQMHKTYIITGGTGGLGLVVAQWLIEE
GAHNIVLLSRRGEPPSSVKAGDPVWKYLCGEEQPNCISVATLKCDVSQKDDLLRVFKEIE
SRGLPPVAGIFHAAGVTADAALASQTADSVDQVYLPKAIGAWNLHDACEALGLNKSLEVF
MMFSSVAALLGNFGQANYSAANACLDALAMYRQSLGLCGQSIQWGPWIEQGMAAQLTQHL
EKVGMRGITNELGLRVLGDVMMHPTVAVVGAQSLQWRKFLRRYAFEMPSFFSLVPMAGAG
SSEASVNLATITKEDLCELISSLAQAVSGAAEKPAVDTPLMDLGLDSLGAVEFRNSVADK
VGVKLPQNLMFENPSISSISDYILDKAAGKHGESGVTGANGGSGEGSDIPALDTPLDQWL
MSVLEPAERFALYIDSFASEYGTLQKMAAEEDIITALEDLGVEDGGDFERLHVAWDDLCN
QINTAKRMAAKDIRPSSTAVSVSDHPKPRMPHPMEDVDTLLASLDFDVSTLRPATAPDKV
KNVLLTGVTGFVGRVQLASLMQLKQRPDLRVYCLVRARNADHALSRIREATKEAKCWQET
FVSRIVPVTGDFTQPLLGLSSEEFQELARKIDIVYHTGGDVNLLSNYGRLRATNVLSVKA
IIDLCTTYKVKPLHFASTLGQFPAFFAMFTGHFSGESIREDSTPDVSQMENFYPPSRQGY
PWSKWAAERVLEGARKRGLPVAIYRLPNTYVAYKTGYTNKTDYATALMIASIQEGVFPIG
AATAPLTPVDTICDMLVEASFLEKPKHWVYHLFDPRLVTRADLEQWSQELGISYVGVKVD
EFLEAIKKRGPESPVFKFVPLMQHWRRFWFDPEERTESFPISNEHIFEDLPHMRWPSLRE
VFKNSLLYSVRMGFFPKNSKSIILDPQVALNEARRICGLQLMGREGEDFFLHPWRVLQES
ARRECDLLFGGQLAVYRTVRHYFMNVMYLADAQAKCPEIEKQEIQAPLIIVGLNRTGTTF
LQNLMSTDPSNRSLRYCEMIAPYGPDGNYRPKGLPNTEESWKKDPRIPFAQEILDSQLGL
SEEWMAIHTQRAELPEEDFVIFEHCGRCYSICTEFSVPSYREWLASDNYKETRKAYSFHK
RFLQHLQWQRPAKRWLLKMPFHLFTLEALFETYPDAKIIFMHRDPKETMGSWASLVKHAQ
QSLMDNVDPSALGREELRAMSTMINRALAFRRSHPELGPRFLDVQYQDLVNNPIGVVKSI
YKHFGIPLTLAAQTGIASFCNENRKHRDKLTKHMYSLKDVDLTDGMVQEAFKEYYDSGLC
KYLSSAR
>A0A0L6JKS6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudobacteroides cellulosolvens ATCC 35603 = DSM 2933|TrEMBL
MGKKLVDLIDIEEIKTGSEKRIEMVSGRDIAVIGISVKFPMADSIDGLWYNLINGIDCIR
HIPDGRRKDIEDYYCFTGRELSEAAYEKAGYLDHIHNFDYAFFGLSPKEASLMDPNQRLF
LETSWKAVEDAGYGGGKLAGSRTGVYVGFSGENEYKKLIGDVEPELLSMAVPGNLSPIVA
SRISYLMDFRGPSMVVNTVCSSSLVAVHLACRAIRSGECDLAIAGGSQIYVLPVREVKIG
IESSDNKTKTFDDNSDGTAGGEGIAAVLLKPLSKALKDRDHIYAVIKGSAVNQDGNSIGI
SAPNPAAQEDVIIRAWKDAGIDPETVTYIEAHGTGTKLGDPIEIEGIQRAFGRYTDKKQF
CAVGSVKSNIGHLDASSGIAGFIKAALALKNKTIPPSLHFSRPNRKIRFHKSPVYVVNRP
QEWLSEGTALRCGVSSFGFSGTNCHIVLEEAPAVYKKGEELMELKILTLSAKSEESLERL
VEEYIEQQDKIIAEGLDNVCFTANTGRGHYGFRLAVILTTDQDFQEKLELIHKQGIKTYP
DQGIYFGSDKDIYKDRGAGGSGEITSLKAGIMSEEANKKINEFVGTKRRDKKILHEICRL
YVEGVDMDWDGFYSGEIRNRVCVPTYPFESTRCWLQIPVRQYPMYHTVVWKNEDLNLLEK
SADEGIVLILEDVNGIGKEIAVRLRNDGMTVIEVECGNEYKKSSTINYTISGDEEDFKKL
FADLRGEKIARIVHMFSITSATVDSVKKLDEKLDNGVLSLFHMYRSLESVGVKDLDVVLL
SQYVNEVDKNEKCINPENAAMFGLGKVINMENPEIRCRAIDVDGETNIEQMILEIYAGYK
EYNVAYRRGKRYIQELDCIDAEEYREKEIKLKHDGVYIITGGLGGLGLETAKFLASKGKI
TIALLSRTKMPEREEWEAILKNGTDKKLCSKIKDILYIEKTGARLVCCSVDVSKEEELRE
TVARLKSRFGRINGVVHSAGIGAGKEGVSIRNDTEEIFKEVLKPKIQGTWLLKQVTGDDA
PDFFAVFSSPITLMGGAGSGSYTSANAYLDSFTAYNNKLGNRTIAMSWAPWEETVKAAGL
VMDKSRHMFDILSTTEITGSFWEVLNKNSPMVIVGRINYKSILFYLEDYLAFRISQRIRS
QMERLSARNETSRENLSILKTADVKLTGREHGWYSTSEKQLANVLGQVLGYNELNINHNF
YELGGDSIIAARAVGILNKQMGLNIKIADLLKNPNLREFAQYIELKYLGKTGEGDKYSEI
PMTGRKDFYKVSSSQRRVYLMNQNDKTGISWNIPYALIVEGSFDLKRFREILGCLINRHD
SLRTSFHEVKGEIVQKIHEDTECPISIREAYEEGMGEIIQEFIKPFDLNKPPLFRTGIVR
FNPLRHLLLFDIHHIIADEVSMEVLVGEITSLYEGKNLPELRIQYKDFARWQDELVAREC
FKEQEQYWLNVFSGEIPVLELPTDYPRPAAYSSEGERVVFEFEKELSARINRLVLETRTT
PYWVLMAVFNILLHRYSGQDDIVVGVPVEGRFHPDLQNVIGMFINVLPLRNYPCANKTFM
RFLEEVKENLLKAYTHQEYPFDVLVERLKIIKSSNRSPLFDVSFQIHKTVLREIILENNI
KFLPVKMENKTSKQDILLEAFETEDRFYFEWVYNTSLFTRESIEQMVKSFIHTAREVVQN
PYIKLRDIRLISGLEKSTLLADFNEEL
>A0A0N1GPI9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MTDRPATTGIPDEPDYDDGTAYDDATAYDEALDDNRVAVVGMACRYPGAADVTELWENLK
NGTDGISRFTEAELTAAGAAEDTVRHPDYVPARGVLADGDRFDWSLFGYSPGEAARMDPQ
QRVFLETAFTALQDAGLDTRRAETWIGVFAGCDVPHADFATEEGLATEMLARDKDFLATR
VAYKLGLRGPAMTIQTACSTSLVATHTAVQSLLNHDCDVALAGGASLRLPAGTGYQYQQG
GIASPDGRCRPFDAGANGTVPGSGVGVVVLKRLADAVLDGDRIVAVIRGSAINNDGNGKI
GYTTPSVTGQRDVIALAHERAGIGSHDITYVETHGTGTAVGDPVELAALTAAFAATGDGR
QRPERCRLGAVKGNLGHTGSAAGVAGLIKTALMLHHRTLVPNAHFAVPARELADSPFEVP
RESGPWPGDGPLFAGVSAFGVGGTNAHVVLESPPQQPDREPELDTPRLLCLSAPAEAGLD
RFRAGLADRLTADQDAPRLDDTSWTLATARQHFPLRTAHVVSGRDTARDALCGPVAAVRA
AADPRQAGIVLTMPGQSGLRPGSGRAAHALLPHFRKAFDRVREESLDRFAIDIAKVLDPA
TSYDWLADTRNQQVVLLALGLALAEQLAAWDIRPTALFGNSSGEYVAATLAGVWDLSDAI
GIVQARGEAMWAAPEGRMIAVSLTAAEAAALAAEHDGVGLAVDSPGHVVVSGRVAAAEAF
AATLERLDVKFTVLRSPLASHSDVMAGAADEMRTVLSRISARPPAVPLVSNLTGSWLTAE
QAADPEYWAAHLCTTVQLTGNIGTLLDGPSSLFLELGPGDSMTRYLRAHPAWGTDRTAAA
TLGRAPAREHESLLETAGRLWERGFEPGWRDLFPDPAPRRTALPPVPLDSRPLPQPRPRH
ASRTTAPSGPGPLLTRRRWSRTDTATRLAYGAVLLVTDTPETGVDRLVDRLGAHSSRTDW
AGAGQDGLPERTSAVVAVLPPADGPQVPDAVRLLAERARERAVPLVLLARGVADVLGDGE
ATRADAAELTAWAARQARTGDGRVRLLDLGPADAAAPEGWPRLQEATALSAWRGRYWWSL
DRETVEHPAESPTPKGPAVGADGVPGAAALVRELAAAGTEIGAFVAAVPDRPALGRIASG
LPLAPAWQRTDRLSARPRLREALDLYCAGLAGRFLLTTGGLAPGDLVGDGELRRRLDPTA
LLPRYTGMLLDALTAEGWLTSAPGASRRLGADFAERVGQALRQGEALDEIPGLRRLLEHC
ADALPDVFAGRRTAVGVLYPEGRPDLMREHLRDNQVVVGDASACLDSLVQTIRALPVDAD
RPLSILEVGAGQAEFAARLLGGWDAREHVSYHVTDVSPLLVRRARQRYADARNMAFSTFD
FTRDPLAQGLVPGSYDLVVAYNSLHVAPEVRQAAGRLRGLLNATGSLCLVEITRPGRWEH
FVWGLAPGWWDFADDLRSDSVHLDRATWRTALRDTGFAEPACLPAADEADHTLLIASRTD
APAPRTGADLVRELAARADEHGCDALIHLVGPDTAATPAAAAALRAAAADGRPVLTVTVD
ATRPEDEWRRRAFDPTAAGGPQRHVEIPQLDAAVLAALPALAGGTALPSTVRLEHPGTPS
TQPEPTAPEPETPTVRPTAVVTERTDPATAALEEVWRDLLGVPARTAGDDFFALGGDSLM
AVHFISRVRDRTGIALPLTAFAETATFGELGALLRAAAPEEPNSRTAPDRSAENGRNIPG
LMVLRATGARTPLFLAAPAVGSSLCYRTLAQRLGDDQPVYGIESPLLDDGLPAGARIEDI
AAHHVDILRRVRPEGPYVVGGWSVGAMVAHEMARQLTATGREVEAVLGIDGYVVDTHGRP
QYTLPELLVQGVRHQAQAALGRRPDIRRMGGDQRVYRRAFQRNVRAMLRYTPRPVPTDAV
VFRAGADADAAALARVRHRIGTLYEGEVDIRATSGTHFTILNDPHVGQVAAGFGERQG
>A0A1V2RR51|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MDVTGVGLSSVMHAAGLNSGKLVGEVEAADLSAMLSAKAGGAAVLDELTADRDLDAFMLF
SSGAGTWGSGGLSAYAAANAYLDALCDSRRGRGLVASSVAWGLWAGIGMAASEGGDRLLH
YGMEGIDAERGMRALGQVLDAGEGSIAVAGFDWAQFVPTYTLHRPSPLLSALSEVREILA
AEAESSVSADTSELAARLSVMPVGDQRQVLTDLVRSNAAAVLGHDAAADVLPQRAFKDLG
FDSVGAVELRNRLSAAAGVRLPSTMVFDYPNAAVLAEYIRGELVDIGGATDGADQGDAVL
ADLDRLAAALESIEGGADVRQDITERMQTMLSRWLRSSGSNESGPGATGRQAITGQLDEA
SADEVLAFINKELGGSR
>A0A7U4DYD6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Serratia sp. AS13|TrEMBL
MSNAEMLKDALPQSLHGFEIAIVGMAGSFPGAADIEAFWRNIAAGVEAIRELSDEELDAA
GTPHAEREQPDFVRRAAVLEDAEAFDAAFFGYSPREAQAMDPQQRLFLETAWLALEHAGY
APGKFPGQIGVFASASNSSYAMSYLLRHPDIQRHVALDGLLSGNNNDLLSTRVAYKLNLR
GPAMTIGAACSSSLLALHAACQSLLAGECDMALGGGVHVGFPLKSGYRYENSGILSHDGR
CRSFDADASGTVAGDGVGAVVLKRLQDALDGGDRIYAIIKGSAVNNDGSSKPGFTAPSIN
GQTEVLRRALVAADVAPESIGYIEAHGTATRLGDPIELKALLNAYGKQRGPDHRCAVASV
KANVGHLDSAAGVTGVIKVAHMLMHRYLPPAVNFSRLNTEIDLRGSAFYIPQQGEPWSSD
RPRRAGASAFGIGGTNVHMVLEESRFVAPSGPGRPQQLLCFSARSAAALRDGMARMQAWL
SSAEENESEGEALADVAWTLQVGREEMNHRCALVCRDRQQARAELAHRLALPEGGKAMAD
ARTIFMFSGQGSQYAGMMHDHYQQEPFFRDVVDECAGLLKPLLGRDIRPLLFEAADDASL
SALYQTRFTQPALFVVEYALSRLLMSWGLAPAACIGHSIGEYVAACLAGVFSLEDGLRIV
VRRAALMNEMPPGKMLAVGLSAVELARRLPDGVSLASENAPEFCVASGESEAIETLQALL
DADGVEAKPLHTSHAFHSAMMEGCLADFERAFDDITLSPPTLPFISCVTGDWIRPEQATS
PDYWVSQLRQPVAFSQGVKRLLDEPQNLLLEVGPGSTLTGLARMQLEGVAARRRVFNGGV
GVKQPRAGLQTLLAALGELWCQGVAVDWPRLYQHQQRRRVPLPGYAFQRQRYTLASLVNS
QSEQLPAVGERLPMAEWCYQSRWKQLPPLSSTPGSWRGRTVVLFMDRLGSGKRLARMLEN
QGARVRRVSKGIRFRILRSGNVTVNPQRPQDFHLLAEYLRSQQQAPDALIHGWSITRSRA
LSAKNATLHYESLLHIARHFHPENDDAPLDLFVLSNHLHALAGDEQIDPGKALIIGPSRI
IPKEFSQIRCKSIDFIPPSRYRGLATTRALSTLLAEMQHTDEALMVALRGAQRYAPLTEL
DRGQQAEPPFSFCDGGNYLITGAFGGIGSTIAENLARRHRARLLFIVRGELPPEAEWESW
LARHDASNAKSRRIAFLRQLQQAGAQVTVISADLADKRSVSRGIAAFTQRYGTLNGIFHC
AGVADGGLIQNRSADDSQRVFQAKVQGTRVLEACLRQHAPDFFVVCSSLAAFVGPVGQVA
YCAANAWQDAWALNAHQRRDARTRYLAIGWDAWRDVGMAVDSLRQWHGDSGEKTLRDAIT
PKEGWTLLTQLLARNGGHYLISTRGLPLVDSDANVQTDIAQPDRDGERLQPALFPRPPLS
SEYLEPRNETERQITAAWQEKMGIGPLGIEDDFFELNGHSLMAVQIIALIRQRLNVSLPV
GFIYDHPTVAALSEQVLMRLQERQPAVEEAK
>D0LQX6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Haliangium ochraceum (strain DSM 14365 / JCM 11303 / SMP-2)|TrEMBL
MSNTDTAPSRKALMRQALTRIESLERELVRARGFRDAPIAVVGVGCRFPGDASTPERYWD
NLAAGRDAVSEVPAERWDASWFDADPSAPGKTYSRHGGFVGEVDRFDAPFFGIAPRDVQS
MDPQHRLLLECVWEAFERAGIPPASQAGSRTGVFVGIATTDYGWVLQERKGASALDAYFL
TGVSPSFIAGRAAHVFGFEGPAVAIDTACSSSLVAVHLACNSLRMGETDVAVAAGANLLL
APMSQVMMAKVSVLSPSGRCRAFDASADGFVRGEGVGVAVLKRLDDALAAGDPVLAVVRG
TATNQDGATNGLTVPSKQAQARVIRAALANAGVDPHEVGYVEAHGTGTALGDPIELRALG
EVYGRGRPAERPLYVGSVKTNFGHTEAAAGIAGFLKVVLALGGEGIPPHLHFQRPSAHLD
WSQLGVAVPTSLVPWGEGRRLAGVSAFGASGTNAHVIVEAPPKSVHTSVNTSAPTTAPAT
ARPELVLVSARSPRALAAQAEAFAAFVDQRPELPLAELAASAAVRRSHHEYRLAVVADAP
TLLAERLRADAAAAPTAEVARGQADPEAPPRVAFVFSGQGSQWAGMGRELLADEPVFRRV
IERCAEAFAAHVDWSLTDALEGRVDLERIDIAQPTLFAMSVALAALWRSWGVVPGAVIGH
SMGEVAAAHVAGALSLEDAARVICQRSRLMRTVSGQGAMAMVELDMDAAEERLRARPGLS
VAAHNGPEACVIAGEPEALDGLLRELEGEGRFCRRVRVDVASHSPQMDPLLAPLERELSA
LAPRPGELPLYSTVTRAVLRGDELDAGYWARNLRDPVLLAPALDRLLGDGFTALVEISPH
PLLLPTLEQRAAERGPGRRGRAGAVGSLRRDSSARQMLLQALGALYTLGAPMQLAALYRE
ARRLPLPTYPFQRERYWMSAGARRAGQERAGDGLLGVGVESAATGQVALWQRWWSGESAG
FLGEHRVSGVALLPSSVLPLMAAEAARRAGLGEALTVSGLAFGAPLALGEVEQERELQLS
WRGAEGPPARFRIASRGPGEAWREHASGRVSAAPSADHAGPPLAEVRVRLPRAVPAEELY
GAMDAGGIANGPGLRTVAELFAAADADAAADADADAGEREVLARLRVDERAARAAHGLGL
HPALFDGALQAVGAALAGSVDGAAPLPSGIERLRVHASPAVSGWSYVRVRRPDAERWRAD
VLVWDDAGALVAEVQGLALALPADAGAQTAGLYQPRWQPAPLPADAETETERDRPTWLIA
AREPALAETLRAALAERGHEAALWLLEGAIAAGDLPALAPAAGGRAFAYLPRAVSAAGDA
AALRAELRGDLEALAGLAASSSEAPALAVIRSVEPVEQSGQAAADAAALSAAADAALRAA
WPGPCAQIAWHREAAPAALARELLAGPGDDEVALRGDGRHVLRLRPPPAAPPLADQAYAG
EPCRLAPPDSDSRAAAAALRPASRRAPGPGEIEIEVRVAAPVGGALACSGVVLACGAGCE
GVAAGDAVLGLVRAPLGSHITAPAERFAAQPAGLSAAAAVASALPYAAAWHGLQAAGGPA
RGERVFVHGAGAGVGLAAAQLALRAGAEVWATAPRERHEALRALGVAQVFDAPASGDELP
ASARGAELVCNAAPGAIASAAALAARGGRLVELAAGAAAAADEDGDEGEGAGPGADEAAL
GLALVRARLSFHSAALDEARPGAYRAALERALAVVAGGELAPLPSRSYPLREAGRALQPA
PAHASAAPLVSFAERAGARLAVPLPAWPGVSGEGAYLVAGAGAAAAGLLRWLAGEGARHI
ALVAPGEPAAALADALAEARAAGARVDLVAPAGDAASSAAGAAPAALTSERWRELLRPDA
AADAGPGRWRGVFLAPAPAGAPAAANLDTAGDDAAAALTSARALLAATEGLSLDVVALVC
GLAADGRGEASAAALSALAAAHSRADRPVLALTLAPPASPGPAADAELARLLSAALASRQ
PRLVALPTPLAPAWVERARARPGYAEPLAAQASAAALGSARSALAALADPALRRAYLEDL
LGAQLAAVLGMDAAQLDRDTLLRGLGLDSLMAIELRARVEQALGLRISLVRLLQGGTVAE
LVDHLVELWEEAEEAAAEPAGDDHPHAERKSHARDR
>J7LIH0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardiopsis alba (strain ATCC BAA-2165 / BE74)|TrEMBL
MLSEGREAISAPPERLGTLSPERGHDWGGYLDDVAGFDAPFFGLSPREAVATDPQQRLML
ELGWEAVENARVAPGTLRGSRVGVFVGAIGSDHHLLQDRGGADAITRHTLTGTHRSLIAN
RLSHTMGLRGPSLTIDAGQASSLVGVHMAVESLRRGESELALAGGVSLILVPESTEAVVR
FGGLSPDARCHTFDSRANGYVRGEGGAVVLLKPLSRALADGDRVHAVVHGGAVNHSGAGE
YLTRPTASGQEAVIRAAYENSGQRPDRVGYVELHGTGTPAGDPVEARALGSVFSKERPDP
LRVGSAKTNVGHLEGAAGIVGLVKTVLSLDHQTLPPSLNFVEPNPDIDLEALRLSVQTRR
EPWPGHAPLAGVSAFAMGGTNCHMVLGPAPLPEQGTVDNGGSGARALDPVPWVLSARSET
ALREQASALHAHVSSRKGTRAQDVGLSLATTRDVFEHRAVVFASGEGSTRELESVLPEGQ
APMDADTPGPVLVFPGQGGQWAEMGRDLLAGDGVLARAFAQRIRACERALEPHVDWSLTA
VLRGDPQAPVLIGEGARVDVVQPTLWAVMVSLARVWETLGVRPAAVVGHSQGELAAACVA
GALTLEEAARVMALRGRALTGLGGSGAMASLGMSAIEAETLTESLPDLYLAAINGPNAVV
VSGEPDSVREAVRRCVDQGLHGAMVDVDYASHSAQVERIRARLFSYLGRVRWQRPKVPFY
STLTGRELGEDSPDLDASYWYSGLREPVLFAPAVAALAGAGYRTFLEVGPHPVLSYGIRR
TLAEQGIRGRVLETLRRGEGDQARLLTAAAHAFTAGVDVDWAGLFEGTGARRTDLPTYRF
QRERHWPRTPVRRPEGASGRSDDLLPDQGVELVDGRTVFSGRIDEAHQPWVRDHGMLGRT
VLSGTAVLELALHAGDAVGAGAVEGLDLTEPVLLSSGDRTTHVQVTVGAAAENGTRQVEV
HSRGTADGEWVHHALGTLAPDRARRETAEPAAWPPPEAVTVDLDPDEAYGRLARRGHTHG
PLNRGLREVWRLGDTLLARVVLPSGHGLPSSVTRSLLLDTSLHAILLFGPRTEGPPLVPV
EWRGVRVLSASVPTEARVALEPVGPDRYQVTVTDRSGTPLLEAEQVRLRSLESETLPPPQ
GEEPGLYRLFWEPLSLPESDGRMPVGLVSPADLAGGGPVPDTVYAELPAREVYAEHEPVP
DAVSEGVEAALATVREWLTDPRTVDSRLVLITWRAVVTSGEDRLGGPAAAPVWGVIRSIQ
REHPGRVVLVDSDGSEDSHRVLVDAVSTGRPQLALRSGAALAPRLAPACEPDRPVPPSAA
WRLGPDPSGSARGPILTAAPEATARLDAGQVRISVRAAGVGQRDVAVGLGLLDERMGLEG
AGVVVETAADVTDLAPGDRVMGVFRGALGPLAVADRRALVRVPEGWDLEQAASVPLSFLI
AYHALVDVAGVRPGESVLVHSAAGGVGLAAVQLARYMGARVFGTAAPHKWALPEEYGVPP
ENLASSRDLDFEDRLRAANGDRGLDVVLNSLTGRFVDASLRLLRSPADGAGAGGRLVELG
VTDVRSEAEVAAAHPGRGYHPLDLSEVCPDRVATVLSRVTELFEAGTLRPLPVTVYDVHD
AREALEALRRGDHVGRTVLTFPEPFPAGATVLVTGGTGEIGHRTARHLVAGYGVRHLTLV
GPGGAAAPGQDGRTGELRSLGAEVEVKACDVADREALSRLLDGLERPLGAVVHTEDAVLD
ESEPIDGVAALRNRVNALWNLHELTLDRELGSFVLFSSAGGVLGAPGRHHSAAADAFSDS
LAHHRRERGLPATSLAWGRWGGLGRALAKLDAALYLESDVYVPALVNKDDAPEHPFLPGV
GTTPGRGGPPRGGARRTRKGRSGPPAEPTRPVVAPPPPVPSTEPKASPERLASLPEGERE
RVLLGRVRAHTAEVLGHAGVAAVPADRSFRDLGLDSMGAVELRNRLSGEVGARLTATAVF
DHPNPRALARLLVGLVALGDTRRSEEEPAATRGTDAGPARDPRVDDDHGVDDIDDMDVDD
LLDLALGAEHLSDGEQETADGHR
>A0A3E2YHD0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MW-13|TrEMBL
MPTEAEFLDYLRRATADLRDARRRVREVEAKDREPMAVIGMACRFPGGVSSPAELWDLVD
SDGDGVGNFPTDRGWDLERLFHVDPDNPGTSYTSQGGFLYDAAQFDPGFFGISPREALAM
DPHQRLLLETSWEAIEHADLDPQRLRGSRTGVFAGVMYHDYASRVLDLPDGVEGYIGTGN
SGSVVSGRVAYTFGWEGPAVTVDTACSSSLVAVHLAVQALRQRDCDFALAGGVTVMSTPG
TFADFSRQRGLASDGRCKSFAASADGTGWSEGVGVLLLQRLSDARRDGRRILAVVRGSAV
NQDGASSGLTAPNGPSQERVIRQALANARLSPADVDVVEAHGTGTTLGDPIEAQALLATY
GQDRGEGGPLWLGSIKSNLGHTQAAAGAAGLIKMIEAIRHGSMPRTLHVDEPSPHIDWTA
GQVSLLTEARPWPASDRPRRAAVSSFGISGTNAHVILEQAPVDDAPPPADAAPPAGPVAL
PLAPVLLSARTAEALAGQAARWAEHLAAADAPRPVDVAVSSISRSGLEHRAVVLAEGPDD
LLAGLRALAGGEPNGTVTTGSASPRGRVAFLFSGQGAQRPGMGRELSAAFPVFAAALDEV
CGHLDPLLPRPLREVMFAAPATPEADLLDQTVFTQAGLFAVEVALFRLVESFGLAPDFVA
GHSIGEIAAAHVAGVFSLADACALVAARGRLMQALPAGGGMLAVGADEAAVTASLAGLAD
RLDIAAVNGPTAVVVSGDADALDELQRTWTDRGAPTRRLRVSHAFHSVRMDPMLAEFAAV
ADKLTYHPPTIPVVSNLTGRLAEPEQLRDSRYWVRHVRGTVRFADAVDSLHAEEVGTYLE
LGPNGVLTAMAQGCLADRPGDEPAPLLVAVSRHDRPEPQAALEALAQLHVHGLAVDWTRL
LAGAGGERVDLPTYAFQHQRYWLEPAGRWTDVSGAGLGAAGHPLLGAAVSVAGEDMVVLT
GRLSVSTHEWLADHVVAGSVVVPGTALVELAVRAGDEVGASRVRELTVAAPLVLPASGGV
RVQVRVGTADAAGLRSVTVHSQPEEDADPEWVRHAEGVLEPVSADEPVLGEWPPAGASEV
DLAGWYPAVAERGLVYGPVFQGLRRLWTAGGEVFAEVALPERVAGDAAAFGVHPALSDAA
LHPIALLFEETAAPRVPFAFEGVQVHASGASVLRVRLTREGSAVRLVAVDSSGAAVVSVD
SLVLREMSGVAAPNPAGRSLFEVAWQAAETAPAGQVVGWALLAAQPGQLHSAGDEGVAGL
AGELADRGGLASYPDLAAVAGAGAAGAAVPPALVLPVSVAPGAAVPDAVREVTSGVLSVV
RSWLAADALAESRLVVVTRGAVPARDGDEVTDLAGAAVWGLLRSAQSEHPGRIVLADVDA
DADAAVLGLLARVADEPLATGGQVAVRAGEVLAPRLVRASVPDPSPVVGEGAVLVTGGTG
SLGALVAEHLVVAHGVRSLVLVSRRGPDAAGAAELVERLAGLGASVRVVACDVTDREQVA
GLVGEVTSAGRLAGVVHTAGVLDDGVVETLTAERLAGVLAPKVSAGWFLHEATTGLDLDL
FVVFSSVAGVLGSPGQAAYAAGNAFLDALAVHRRRAGLPAVSLAWGMWDTPGMAASLGEA
GRTRSTTRGGLAAMSAETGLALFDAAVSGGRSALVPAVIDVAALRAAAGTGMVPPMLRAL
VGATTIRRQAGQGATWATRIAGLAPEEARAQVDVLIRGLVAQVLGHGGAESVPADRAFRE
LGFDSLTAVDLRNRVNAASGLRLPSTLVFDYPTPQALAAHVHAELAGAGSGVAASGARTT
TGLDEPIAIVGMACRYPGGVETPEQLWALLAGGGDGIGEFPADRGWDLETLFDPDPDRPG
SSYTRHGGFLYGAAEFDPAFFGISPREALAMDPQQRLLLEASWESFESAGIDPQRLRGSR
TGVFAGVMYHDYASVLMDVPGEVEGYIGTGNSGSVLSGRVAYTFGLEGPAVTVDTACSSS
LVALHLAAQALRSSECDLALAGGVTVMATPGTFIEFSRQRGLSQDGRCRSFAASADGTGW
SEGVGVLLVQRLSDAQREGRNILAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQALANAR
LTAADVDAVEAHGTGTTLGDPIEAQALLATYGQDRQADRPLLLGSVKSNIGHTQAAAGVA
GVLKMIMAMRHGLVPATLHVDEPSPHVDWASGAVALATEATPWPAVNRPRRAAVSSFGIS
GTNAHVIIEQPPAPVIEGEPVAAPRTGVVPLVLSAADGPALREQAARLHAHLAAHPEIEP
ADVAHALATTRAAFPHRAVLLGRDTTDLVRALDAFRLGEDVPAAVTGTALRGGDPVLVFP
GDAEQWPDALADLLDRSPVFAESVAECEAALAPWVDWSLTAVLRGADAPSPTRPGVAQAA
RWAVAVALARLWRSLGVRPAAVLGHGDGEVAAACVAGALSLADAAKVIALGSRPPAAADP
ADPDAAPDRPTAGLAGITLQAAEVPLHSASTGVPVDTAGLDAADWYPGLRADADPDAAAR
ALLDAGHQVFLEVAPGPALAAGLRRAVAAAGHDAVVVDTLPPDAAGWPALVAALAELHVH
GAPVDWTAVLGARPGPAVELPTYAFQRQRYWPQPTGPAGAAVAAGGDDADRHFWAAVEQS
DPRALAAAMRIDETDARSLDPALPLLSSWRRRRRDESTVDSWRYRVTWKPLPTPADAALS
GRWLLVVPAGRADHPLAVAAAAALAEGGADVVRVPVADPDRAALADQLGRSAGDAAPVGG
VLSLLALDDDAHPAQPVLPAGLAGTVALVQALGDAGIAAPLWCASTGAVCTGRADPLDRP
GQAAVWGLGRVVALEHPDRWGGLVDLPAEPDARDRARLVAVLSGVDAEDQLALRPSGVFA
RRLVRARADRAPADGWRPRGRTVLVTGGLGSIGAQVARWLAREDAARLVLTGRQGPATPG
AAELAAELTAAGATVTVAACDVADADALRALAAELAAQGVRVDAVFHTAGVAHAGPVAAL
GPADLADALRAKVSGAVHLDEVFGDDLTAFVLFSSGAGVWGGGHQGGYAAGNAFLDAFAE
DRRRRGRPATAVAWGAWDGGGMVDAEGAADQMFRSGVRAMRPDLAVSVLADALAHDETTL
TVADIAWDRFLHTYTLARPRPLIGDVPEVARLLAAAPSGDAPAAHSPLRARLAGLAAPDR
RRVLLDLVRVHAAAVLRLPSAEALAADRSFREIGFDSLSAVEMRNRLAEAVGETLPATLV
FDRPTPGALADHLASRLTGDDAPAVAPTRAATALDEPIAVVSMSCRFPGGVASPEDLWRL
VSEGRDGIAEFPADRGWDLEAIYHPDPDRPGTSYVREGGFLADATGFDAALFGISPREAL
VMDPQQRLLLESAWELFERAGTAPADLRETGTGVFVGTNGQDYATLLLAARVETEGYQAT
GNAAAVISGRLAYHFGLQGPAVSVDTACSSSLVALHLACQSLRQGECDLAVAGGVTVMAT
PGPFLEFARQRGLALDGRCKSFAGAADGTGWGEGVGLVLLQRLSDAQRDGRRILAVVRGS
AMNQDGASNGLTAPNGPAQERVIRQALANARLAGADVDVVDGHGTGTRLGDPIEAQALLA
TYGRDRPADRPLWLGSVKSNIGHTQAAAGVSGVIKMIMAMRHDLLPPTLHVDEPSPHVDW
SAGAVALLTEPQPWPEVDRPRRAGVSSFGVSGTNVHVILEQAPAEPAAPAATARPADGAP
AGLPVLPWVVAADGAESLRAQAARLADWLPHQPTPDVDVARGLATGRSPLRHRAVLLAAD
RDEALAGLRALAAGQDHPGLTRGVAEPGGALAVLFSGQGAQHAGMGRRLYDTFPTFARAV
DEACQHLDAYLPRPLRPVLFAESGTADADLLDQTVFTQAGLFAVEVALYRLLEHWGVRPD
FVAGHSVGEIVAAHVAGVLSLPDACALVGNRGRLMQALPAGGGMLAVAAAEVEVTQALTG
YAGRVAVAAVNGPTAVVVAGELDALTELADHFTALGVRTKRLRVSHAFHSPLMEPMLADF
AAVAATLEYAPPAVPVVSNLTGTVVDADELCTPDYWVRHVREAVRFADTVTHLHSHGVTR
FLEVGPDTVLTALTADALPADAPVTVTGVQRPGQDEVSTLLGALARLHCQGTAVRWPALL
PGAGPVDLPTYAFAHQRFWPTLHAAPADAPGAAGDDTDSAFWRAVVDGDGDALAGRLGVD
PDRPLRDLLPDLAAWRRQQREDTLVDGWRYRITWRPQPLAAGAPGGDWTLVHTAAGQDVA
DRLAALVAARGGTPRLLPVDPATADRAALAGLLDGVPPTRVVSLLALDERPHPDRPAVPV
GLTANLALIQAVTDALPPVPLWLLTRQAVGTGADDPVANPAQATTWGLGLVAALEHPRHW
GGLLDLPATLDDAAAEHVLAALTGAGGEDQIAVRPAGAYLRRLARAPRADRTGSPGWQPP
GTVLVTGGTGAVGRYAAGWLARHGARRLLLVSRRGPDAPGAAEAVAELAALGAQARVLAC
DLADRDAVADLVSGLNADGETVHALVHAAGVGRLNPIAAVSGAELADVVSGKIAGARHLD
ELLDPGPLELVVHFSSIAAVWGVGDHGAYAAGNAFLDAFAQSRRASGTRVLSVNWGPWAG
GGMVTDAHAAAMSRRGVSLLDREPAMAALRAGIEGDDDVLTVADVDWERFAPVFASARPR
PLIGDLAEVAAQAAADRADASDGDQVAAELRKRLGELTQAEQNRVLVDLIRTAAGEVIGH
DSPYAVESSRPFRDLGFDSLTAVELRGKLARLTGLNPPSSVVFDYPTPLALAEHLRSELL
SEASVEALPTLAELDQLESALALRDPDDTGRVRITMRLHHLLERLGAAEPRREEAAEVAD
RLRVASNQELFDLIDQDLGLS
>K9QEH2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc sp. PCC 7107|TrEMBL
MSVSTSLNGSEIAIIGLSGRFPGAKDIDEFWYNLQNGVESVSFFTDEELLSAGINSSLLN
DPNYVKAQAILADAEYFDAEFFGFNPREATITDPQHRVFLECAWSALENAGYDSHNYQGA
IGVYAGSGMNTYLLNIYLNQNIIGSVDPQQLVLAGNKDFLTTRVSYKLNLEGPSYAVQTA
CSTSLVAIHLACQSLLNGECDIALAGGVAINASRKDGYMYTEGGILSADGHCRAFDAHAQ
GSVGGEGVGIVVLKRLEDALSDRDTIHAIIKGSAINNDGAFKVSYTAPRIDTQAKVIRTA
QIVAEVEPETITYIETHGTATALGDPIEIAALTQAFRTSTQTTGFCAIGSVKTNIGHLDT
AAGVAGLIKTVLALKHKQIPPSLHYSAPNPEIDFANSPFYVNTKLAEWQTNNIPRRAGVS
SFGLGGTNVHVILEEAPVWEQDREPGRKYQLLLLSAKTASALETATTNLADYLQAHPDLN
LADAAYTLLFGRRTFDYRRAVVCRDIPDALKALQNSQSVAQKTQARPVAFMFSGLGTHYV
DMALELYQTESTFRVCVDECCERLKHLLGLDLRDVLYPNRNSNHSNQQTQKKLDLRKMLG
RGEPSTDVATQKLNQTVLTQPAMFVIEYALAQLWISWGICPTAMIGYSIGEYVAATLAEV
LSLTDALTLVARRAQMIDELPAGAMLAVPLSESEIQPWLNEKISLSAINGASLCVIAGFP
DEIAELEQKLSDRNLIGKRLQTSHAFHSVMMEAIAPTFANLVNTFSLNPPKIPYLSNVTG
TWITTEQATDPTYWVQHLCQTVSFADGVQQLWQKDNPILLEVGPGQALISFASQCLTTDQ
RNQSLMLPSLRYSYEQQSDVACLLQTLGRLWQAGVAVDWSSFYTDAPRQRIPLPTYPFER
QRYWVDAHPTANLLLRCAPGETSNTIDGLNQDTQTTPTTSATAYLRPNLDNDYVAPKTEV
EQIIANIWQELLGIASVGIEDSFFELGGDSVLGIQVSARAAKAGFRLTPQQLFEHQTIAK
LAEVVSTTQLVQAEQGLVTGSLPLTPIQHKFFERNISQPHHWNQSIFLEAPATIDPGVLK
QAWQQLLLHHDALRLRFTPSESGWQAVNGGQEEISFTQIDLSALSTVAQELTIKTTTAEL
QASLDLSAGPIIRVALFNLGVNKSSRLLIVVHHLGTDPGSWRVLIEDLQTAYQQICQGNA
VELPPKTTSYKQWALRLEEYARSANLQKAQNYWLSDRYKQVSPLPRDYANSINNMASEQI
VSVTLNAQDTQALLQEVPATYRTNTQEVLLTAFAQASAQWTEEKLVLVDLEENGREVSTS
GIDNVDISRTVGWITTTYPVLLDLETADNPGDALKVVKEQLRSISGQGIDYGVLRYLHPD
RVVQEKMRSLPQAEVAFLYVGQLSKSLPPDSLFQLSADSPEAASSLQATRPHKLHLIVSV
VAGELQLDWYYSQNVHQRQTIEKLANNFVTALQSLIFHCQSRTTVEYTPSDFTAANINQE
NLNNLLAQIGQSGHKLGTSP
>A0A655DQR6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MVAARANVVGRLPGRYAVAALGIGEQDASALIATTGGWLELSVVNASSTVAVSGERQAVA
AIVDTVRSSGHFARGITVGFPVHTSVLESLRDELCEQLPDSEFMEAPVQFIGGTTGDVVA
PGTTFGDYWYANLRHTVRFDRAVESAIRCGARAFIEISAHPALLFAIGQNCEGAANLPDG
PAVLVGSARRGERFVDALSANIVSAAVADPGYPWGDLGGDPLDGDVDLSGFPNAPMRAVP
MWAHPEPLPPVSGLTIAVERWERMVPSTPVAGRHRHLAVLDLGAHRALAQTLCAAIDSHP
DTELSAARDAELILVIAPDFEHTDAVRAAGALADLVGAGLLDYPMHIGARCQSVCLVTVG
AEQVDAADAVPSAGQAALAAMHRSIGFEHPEQTFSHLDLPSWDLDPVLGVSVITAVLRGF
GETALRGSVNGYTLFERTLADAPAVPNWSLDSGVLDDVVVTGGAGAIGMHYARYLAEHGA
RRIVLLSRRAADQATVAMLRKQHGTVIVSPPCDITDPTQLSAIAAEYGGVGASLIVHAAG
SVISGTAPGVTSAAVVDNFAAKVLGLAQMIELWPLRPDVRTLLCSSVMGVWGGHGVVAYS
AXXXXXXXXXXXXXXXXXAQGRHCVAVKWGLWQAPKAGEPARGIADAVTIARVERSGLRQ
MAPQQAIEASLHEFTVDPLVFAADAARLQMLLDSRQFERYEGPTDPNLTIVDAVRTQLAA
VLGIPQAGEVNLQESLFDLGVDSMLALDLRNRLKRSIGATVSLATLMGDITGDGLVAKLE
DADERSHTAQKVDISRD
>S8G4P4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii (strain ATCC 50611 / Me49)|TrEMBL
MANAEKLVKLHGLWFRSLWKWAEKIPHEDAVIWLDENGSKAASLTYQKLRREALIIATCL
RQVHCQPGDRAILCYPPSVSFVPAFLGCQICGLTAVPVYPPGSNDRDSDSIQRIVAMVKT
TRPSVVLSSSPLRYFLKEVFPGAAARCVSDIRWIFTDELPDHVEAGSAFELDSLDIKSET
PAFIQFSSGSTGNPKGCVVTHMALLHNIHLNWRMCGAFHPGTEESLYDLPVESYAEFTEK
YQKHLVATWGHRLRSFSWLPVTHDMGLVGMLCVPLFFGCTAFFMSPIDFVRAPHSWLGGM
SKFGCSFTAAPDFAYALAARKVPDDLVLELNFEKILACVNGAEPIRPATIEAFLQKFAPA
GFQPWMMSPAYGLAEHTVGVTGRGSEGRKPMSPKIIEVNNEKVAQGDTVELFKRSGKQEN
EMRTKLIVGCGIPHEDVIVKIVDPRLLQELSEWQVGEVWVSSPSAASGYFGSPVETASTF
NLHLNTADGATRGDRSFLRTGDLGFLGDGELFITGRLKDVVILRGCNYYPQDIEEAVERC
DSVRKGGVMAFSISTTDDAEGLGVAAEIQKGSEKPAKLKLIYADIVRTVNKVLHLPLQRL
WLLRAGSLPKTTSGKPRRSEARRRLLQAERCDDILYSYTRNLSHSGHLPFRPGTFELDME
QKQEDSASTSKSEVNKSLVESLSTAKGARHTDDGFIFTNGQQNLHEAKKDQHGTSDSTLA
EPVSNAILDPITRVTDALLVTADGTSVHKDEEELSLVAECFACVTGVEKSCLRPDTPFLS
LGLDSLTAVELANEIQRRMKQPVEPFELFEFADLRSLALYLRNKKLDHGKDARGRQTKSS
PERSLGIVQVQRPSVFVTGVACALPGSCQTPDKLWEILDAGIDCVGPIPPNRNFCASQNF
AVIGEPRTANASFCVTEGGFLDDVDLFDNSSFGIPDAEAMTMDPQQRLLLMKAVEALHAA
GMATIDSRSAPIATFVGCCSTDWQRMNLGEQIQSFSATSHSASMLSNRLSYTLGLTGASI
TVDTACSSSLTALHCAMQELQHRHVPCHTAVVATVNLLLTTDVTLAFARAGFLSPTYRCK
TFDDAADGFVRSEGVVVFVLQTDVSETPTPSFKNQQEDNEGGQGECGTRIPASGYLCRIL
ASTVVHGGKTGSVTAPSGSSQELLYKQTFACAQVPPRAVDLVETHGTGTRLGDPIEISAL
CNSFAPDMETRKHRLVLGALKTNLGHLEGASGLAGLLKSVLCLNRQRVPPNLHLRKLNRF
IDFRSLPVLLPTKTVPLPASSSETKEAVALVTSLGFGGTYAQVAVQVPSTTGNEMLLRNQ
EPVQWNKKCFDVGKLVSQSNSFQSAVSHNDTKGPCFWEVGWEFLLEFDSITLTLPTLPEQ
APPAKWLVLTSPKAQQSFRKFSVNIFLPGIRMTFACLEELKAPEHLEAILKAETWTAIVS
TYTTETGSCMTDSSDLIGRTLQILQTYGQMASQSAVLPRILFLTQGCFQVGAAASLLRAS
PYNAGIIGFVRACRLEIESLSGRKAPIYLIDFAANGTLTETLSAVSKLLGMIDIRNVDET
EFAICGKRVFAPRLLPLHLGLEEILPAYDHYMDLTKKADESPAGTAKFPRLVEPANKACR
VRLLALCLDEIFPIEAISPASKAFELGESRPCTLPYGYRNRRQKAFLYQMERAFV
>A0A222E797|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Antarctobacter heliothermus|TrEMBL
MNEHDEERSVAVIGMGCRFPGHVDTPQAFWDLLRDGRDAIGPIPPDRIEVDRLFDGEPAM
PGHIMSRYGGYLDQIDHFDAGFFHVSPREAARMDPQQRLILETAWEAMEDSGTPADRLSG
RRVGVFVGQWLHDFEMRLLADPEITDFEMTIGSGRYTIAGRLSNLLNLQGPSLVLDTACA
SSLTAVHLAVQSLRTGESAMAFAGGVNVILNPHITIGYSQARMMAPDGHCKFGDAAADGY
VRSEGAGMILLKRLSDALADGDRIHAIIRGSALNNDGNSSGSFGRPSRLGQEALIAAAVK
DAGVFPASVGYVEAHGTGTRTGDPEELAALTAVLGRDRATPLRVGSVKTNIGHTEGAAGI
AGLMKAVLAVKTGEIPASLHFRTPTPAFDWPAHPVEVAAETTRWDTAERIAGISGFGISG
SNAHVIVQSALVREVRGTEATVRHAPVLPVSADSESALRALALRHADLLESQGDIPVADW
CAAAADRRSALGFRAAFPVADRFALVAALRAFGNGGAPALSGRAPAQGAPSIVFVAPGQG
GQWVGMARHFLDHTPAFRAAITECETALGALVDWSLTEQLRLDKDAAGWKLDRIEVIQPV
LAALAIGYARLWISLGVRPTCVIGHSMGEVAAAAISGRLSVADAMRVVVNRSALMARTSG
QGGMALVELVGADLDTRLSPFTGRLSVAAYNSPRSCVISGDAGALDDLLAELERDGIFCR
RINVDVASHGPQMAALAEPLDAALRGIAPVEAGLPMFSTVTGAAVGDVPLDAGYWTRNLC
EPVRFVDAVSAALDAGASAFVELGPNPVLMASVEQILAGAGRDPALVVSERRDRAADEVL
AEGIARLWVSGVKVDWAAYAPPSSTDIPLPFYPWQRERHWHEAADLRPGGMSARAPQMPE
ATRALLHEIRWTEAPQSTVPASPAPGSWLLLGDPQVCTPIAEALSAHGASARIAPLDAAR
AAMGDAGDTASVLVVAPDAGAGFLPVAIVKDLRDSGLSPDRLVFVTRGATLARGDAQPVV
VDQAALVGAARVVAEEHPELAIRLIDAEAGPLSANSAAAIAAQALAADAEQEIALRGSTA
LVPRIGPMEGRSTLRPGFALRPDAAYLVTGGLSALGLRAASCLVRAGARHVVLLSRRPLP
PRAEWRQAMNDPETERRISGIVALEAAGATVEIATADVSDETAMRALLAEREAALRPSIG
GLVHLATAYDTRLATEMDRESYARSVMTKLEGARTLDRLFPELDLFVLYSSTMTFVPHQG
LAGYAAANCGLDALAADRRARGQHALSVAWGPWNALGRAALDHVADEFEARGELFLEPEE
GDALLSHLIFREVGPTVSCFRMDWARFAESRRGRAMDLFADLVAPGSGSAEDATEFSALT
GRQRRKAAERFVPEAVRQVLSLGAGEVDLDRPLGHLGLNSLMAIELRNALEKSVGRPLPA
TLAWSYPTAGALIEYLAADAAAQPAAPPDTAPAAATPGDLAQDLSKMADMSDEEALAALM
GGDR
>A0A2P8AKP0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MH33|TrEMBL
MLTSRRGADTPGAAELLADLAALGVDCRVARCDAADRAGMADLLADLRRDGPPLRAVVHA
AGVSEVVPLAETTLEDLAYVIGPKLAGAELLDELLDGVELDAFVLFSSIAAVWGSGGQGA
YAAGNAYLDALAERRRAHGLAATSVAWGPWTESGMFGEDAPEQLRRRGLRVMPPGLAMAG
LRHALAAGDTCVTVADVDWATFHPLFTALRPSPLLADLPAVRALAARPAEPAGPAAPTGR
DLVAELRPLPAEERRAALLDMVRTDAAKVLGHPSADAVDADRGFLDLGFDSLTAVELRNL
LTAATGHELSTTVVFDHPTPAALADHLYAELFPDEGDPGEGGDEETVRRVLAAIPLDRLR
QAGLLDQLLRLGRDTAGPAPTVGAPPAAPEGEIRDLDVAGLVRMALEGSDS
>A0A2K8QWX2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MSETKLRDYLKRATASLHETRQELKELKDRDREPIAIVGMGCRYPGGVESPEDLWELVAS
GTDAVSTFPVDRGWDEDLYDPDPEKPGKSYTREGGFLHDANGFDASFFGMSPREALATDP
QQRLLLETSWEALERAGIDPASARGSRTGVFVGVMYNDYGSRIQSIPEGLEGHLGNGSAG
SVASGRISYTFGFEGPAVTVDTACSSSLVALQLAVQALHKGDCSLALAGGVAMMATPGVF
IEFSRLRGLAVDGRCKSFSNAADGTGWSEGAGVLLLERLSDAQRNGHQVLAVVRGAAVNQ
DGASSRLTAPNGPSQQRVIRDALRNAGLSAADVDAVEAHGTGTPLGDPIEAQALLATYGK
ERAGADRPLWLGSFKSNVGHTQAAAGVGGVIKMVMAMRHGVLPKTLHVEEPSEHVDWSAG
AVSLLTESTPWPETGEPRRAGVSSFGVSGTNAHVILEQAPEAEAAGDAEPEAADGPVAWV
VSGHGAEGLRAQAERLREFVAGRSELGAADVARSLVMTRSVLDHRAVLVGRDREELLSGL
GAVAEKSALPGVVVGESAPPGRSVFVFPGQGAQWVGMAVGLLESSPVFAEAIGECEAALS
AYVDWSLTGVLRGVEGAPGFDRVDVVQPVLFAVMVSLARLWRSVGVEPDAVMGHSQGEIA
AACVAGGLSLGDAAKVVALRSQAIAVGLAGRGGMVSVGLSAQQAEERIARWGGAISVAAV
NGPGSVVVSGDPGALDEMVAELEGEEVRVRRVPVDYASHSAHVEGIREELLRVLADLQPR
SSEVPFYSTVSGELVDTAQLDAEYWYRNLRQTVELESTTRTLLDAGHGVFIEVSPHPVLT
VPVQQTVEAAEAQAVVVGTLRRDEGGLERFLTSAAEVFVNGAEVDWAAVLENRGGRQVEL
PTYAFQRERYWLDVPAGVGDVGSVGLGSLGHPLLGAVVSLASGGGVLLSGRLSLATHEWL
ADHAVHGVVLLPGTAFVELVVQAGDQVGCGRIEELVIEAPLILPEHGGVRIQVEAGEADA
SGFREVSVFSRDEAEGEGAVWTCHARGVLAPMAGSDAASFDFGVWPPVGAELVDVSGEYV
RAVENGLEYGPVFQGLRRAWRRDGEVFAEVGLPEGERERAGQFGLHPALFDAALHALGVS
GVLAGGSGSLLPFSWRGFALEAVGATSLRVRLASVGAGSDAVSVLVGDESGRGVASVESL
VLRPVDADQLNAVGGAARDALFRLEWVDAPGAVAAVGEVAPRTEVVRVVSDGPDVVSEVY
GRVLEVLERVRAWVADEGLAGERLVVVTRGAVDAGDGVEDMAGAAVWGLVRSAQSENPGR
LVLLDTDDLDGVDSLLPGVLALGEEQVLVRSGVLRMPRLGRVPVPDPSEPGGFGSGAVLV
TGGTGVLGGVVSRHLVARHGVSRLVLLSRRGAEAEGAAELRAELEGAGAEVVIAACDAAD
REALAGVLSGLPEGYALSGVVHAAGVLEDGLLTSLTRERVEPVLRAKVDAAWNLHELTAG
MDLSAFVLFSSAAGTLGGPGQGSYAAANVFLDGLASWRRAQGLPGVSMAWGLWAEASGMT
GHLGERDLRRVSRSGLVPLSSDEGLELFDAALVADETVPVPVRLDIPALRAQGAELPALF
RNVVPTATARRVARSEQDESLPDELRRRLVGLPRTAQDQMLLELVRVQTAAALGHATPET
VNTRRPFKELGFDSLMGVDLRNRLTAETGLRLPATLVFDYPTPMALVGHIRDEILGGDGA
PSSAGAAAVAAPGTPVDSDPIVIVSMSCRFPGGVRTPEELWQLVMAGTDAMSEFPSDRGW
DLERLYDPDPDREGTYYAQNGGFLYDAHQFDPAFFDMSPREALATDPQQRLLLETSWEAF
ERAGIDPTTKRGSRSGVFVGVMYNDYGTRLRQVPEGFEGSLGSGSAGSVASGRISYTLGL
EGPAVTVDTACSSSLVALHLAAQALRQGECDLALAGGVSVMSSPGAFVEFSRQRGLAADG
RCKPFANAADGTGWSEGVGMLLVERLSDARRNGHPVLAVVRGSAVNQDGASNGLTAPNGP
SQQRVIRQALSSARLSTADVDVVEAHGTGTTLGDPIEAQALLVTYGRGRPEGRPLLLGAL
KSNIGHTQAASGVAGVIKMVMAMRHGVLPQTLHVDEPSREVDWSAGEVRLLTEATEWPET
GQPRRAGVSAFGVSGTNAHTIIEQAPPVDEGEGEAEEGPASGADSGAAAWLLSARGADAL
RAQAARLRAFLLERSELSALDVGHSLVATRSMFEHRAVVSGADRAELLAGLEAVASGEVA
PGLVQGVANASGPRAFLFSGQGAQRLGMGRELYEAFPVFAQALDEVCAHLDVLLDRPLRE
VVFAAEGSADAGLLDQTAFTQPALFAIEVALFRLLEHWGVTPDVLIGHSVGEVAAAYVAG
VFSLEDACALIAARGRLMQALPEGGAMVAVQASEEEIAASLAGHEAEVSIAAVNGPKAVV
IAGDEAAVLEIAAQWSGQGRKTRRLRVSHAFHSPRMDAMLGDFRKVVEGLSFGPPTIALV
SNVTGEAASGDDVCSAEYWVRHVRQAVRFADGVRALEKLGVTSFLEVGPDGVLTAMTQDC
LIAGGASASVVAPVLRKDRPEVQALTAALAELHVHGVEVGWERVFAGRGARTVELPTYAF
QRQRYWLEDRAETSAGSLPGGSAAVDSVDARFWDAVEREDLETLAEALDVDGSGSLGELL
PALSSYRRQQRERITVDGWRHRVSWKPVPEVATGSLSGTWLLVVPAGLADSPLTGTISQG
LEKSGARVVPVAVDAGADRAGLARTLLTAVDGESDVRVLSLLALDEEPMSGEPAVAAGLA
LTLWLVQTVAGLGVRARLWCASRGAVSVGRSDRLASATQAQVWGLGGVAALEHPQLWGGL
VDLPETLDERAVSRLVGLLSAEGGEDQVAVRGSGVFVKRLVRASASEATGADGWRSGGSV
LVTGGTGALGGHVARWLARTGAEHLVLTSRRGMEAEGAVELKAELEELGARVTVAACDAA
DRGALAAVLEAIPSELPLTAVVHTAGVLDDGVLDALTVERAAGVLRPKVDAAWNLHELTA
GMDLSAFVLFSSAAGTLGGPGQGSYAAGNAYLDALALQRRADGLPATSIAWGAWAGSGMA
VDGELEEQMRRGGMAPMNPDLAISALQRTLDLDETFLLVADAAWERLAGELGADRPIPLL
SELTERPRPTASLTPSDPAVTESAAAELRASLEALPSAKRQRQLRKLVRQHVAAVLVHTT
PDAIENDRSFTELGFDSLTAVQLRNRLGAITGLELPTTLAFDYPNLIALAEHLEAGMFPQ
GDGAEQNDSEEDRIREALVSIPLARFREAGLMDTLLELARKPESGSESAPQEELSSAVDT
MDVDDLVQRALGGADL
>A0A2K8QWX3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MVNEDRLRDYLKRVTADLHQARQRLRELEAGEQEPIAIVAMSCRFPGGVGSPEDLWRLVA
DGGDAISDFPSNRGWDVDGMYDPDPESSGTFYSREGGFLHDADEFDAGFFGISPREALAM
DPQQRLLLETSWEVFERAGIAPGSVKGRRGGVFVGAATSGYGADVDGFPEEIEGHLLTGT
ATSVVSGRISYTFGLEGPAVTVDTACSSSLVALHLAVQALRQGECDLALAGGATVMSTPG
AFVEFSRQRGLAPDGRCKPYADAADGTGWSEGVGMLLVERLSDARKNGHPVLAIVRGSAV
NQDGASNGLTAPNGPSQQRVIRDALTSARLAPSDVDVVEGHGTGTSLGDPIEAQALLATY
GQDRPEGRPLWLGALKSNLGHTQAAAGVAGIIKMVMAMRHGVLPQTLHVDEPSRQVDWSA
GEVRLLTEATAWPETGQPRRAGVSAFGVSGTNAHTIIEQAPPVEDEAEESPASDAGSGVA
TWMLSARGADALRAQAARLRAFLLERVESSALDVGHSLVATRSMFEHRAVVSGASRTELL
AGLEAVASGEAAPGVLQGVAGTAVKTAFLFSGQGAQRLGMGRELYDSFPVFAQALDEVCA
RLDMVLDRPLRDVMFAAEGSADAELLDRTAFTQPALFAIEVALYRLLEHWGVTPDVLIGH
SIGEIAAAHVAGVFSLEDACTLVAARGRLMQALPEGGAMVAVQASEEEISGSLTGREAEV
SIAAVNGPTAVVIAGDEAAALEIAERWSEQGRKTSRLRVSHAFHSPRMDAMLDDFRRVAR
DLTFQTPTLALVSNVTGEPVGADEVCSPEYWVRHVREAVRFADGVRSLQAQGVTAYIEVG
PDGVLSAMARDCLAGEAASAPAVVPVLRKGRPDAQALMAALTEAHVHGVTVDWERVFAGR
GARKVELPTYPFQRRRYWLEGTGGASGASTAADSVDARFWDAVEREDLEALAKALDVDGG
GSLGELLPALSSYRRQQRDRATVDGWRYRISWKPVSETPAATLSGTWLVVVPASGVADTF
AESVSAALQRHGADVVRLVADEADLAPGALAERVREMATEPSGIGGVLSLLGVDERPCAE
HPVVSRGLALTLMLVRALAEADIQARLWCATRGAVSVGRSDQLTSAVQAEIWGLGRVAAL
EHPRIWGGLVDLPETLDERAAARLAWALSAGDGEDQVAVRGSGAYARRLTRVTVGNESAE
RVWRPRGSVLITGGTGALGAQVARWAVREGAEHVVLTSRRGPSADGVSELTAELEALGAE
VTVAACDAADRDALAEVLAAVPERYPLTAVVHAAGILDDGVLDGLTVDQLAGTLAAKAEG
ARHLHELTAELSLDAFVLFSSFAGAIGGAGQAAYAAANAYLDALAQRRRAQGLAATAVAW
GPWAEGGMAASGRAGERTRGGPLPPMAPSLALDALGWAAGHDEAALIVADIDWTGMASML
SAGPSALVSDIPEARELLAAAAGTIGQAGPGHDLRGQLAGQSDEEQRLLLLDLIRTHAAS
ALGHFSADSVEPGRAFRDLGFDSLTAIELRNRLDMATGLRLPATLIFDYPTAEVLADHLR
QELGGTHAEAATSAVSHRVRPDDDDPIAIVAMSCRFPGGVETPQDLWRLLAEGGDGIAGF
PGDRGWDVEGMYHPDPEHPGTFYAREGGFLYGAAQFDPTFFGISPREAIAMDPQQRLLLE
TSWEAFENGGVKPASLRGTRTGVFVGTNGQDYSAIMLDAPEDFGGHVGTGSAASVVSGRI
SYTFGLEGPAMTVDTACSSSLVALHLAVQALRQGECDLALAGGVSVMSTPGAFVEFSRQR
GLAPDGRCKPFAEGADGTGWSEGVGMLLVERLSDARRNGHPVLAVVRGSAINQDGASNGL
TAPNGPSQQRVIRQALSAAGLSAAEVDAVEAHGTGTTLGDPIEAQALLATYGQERPEGRP
LWLGAIKSNIGHTQAAAGVAGVIKMVMAMRAGVLPKTLHVNEPSRQVDWSAGEVRLLTEA
TEWPETGQPRRAGISSFGLSGTNAHTIIEQAPEPAEAVASEAAGPGTPVSTAVVPWLVSG
KSREALRAQAERLYRDVAAREDVEVLDVGHTLAARSVFEHRAVLVGEDRETLLRGLRAVA
EGGIASGVVQGQAVTGGRTAFLFSGQGAQRLGMGRELYDTFPVFARALDEVCAHLDVLLE
RPLRDVMFAAEGGSDAELLDQTAFTQPALFAIEVALFRLLEHWGVTPDVLIGHSIGEIAA
AHVAGVFSLEDACTLVAARGRLMQALPEGGAMVAIEVSEEEIAASLAGRAAEVSVAAVNG
PTAVVIAGDEAAALEIAEQWAEQGRKTRRLRVSHAFHSPRMDAMLDDFRDVVTGLSFQAP
AIALVSNVTGEAAGPDEVCSPEYWVRHVREAVRFADGMRALSAQGVTRFLEVGPDGVLSA
MARDCLTGDQAAASAVVPVLRKDRPEAQALTTALAELHVHGASVEWESVFAGRGARTVEL
PTYAFQRERYWPEVSLSLSGLDAQGAADSVDARFWEAVEREDLEALAETLDVDGETPLRA
VLPALSTYHRNRRDQSTIDNWRYRVAWKPVPDVAGGPLSGTWLVVVPASLAEDELVTEAV
AGLRRHGADVVSLVADECDLDAGELGERLRAAVADAPAVGGVLSLLALDEEPCSGHPELP
GGLALTLTLVRAMADTGIEASLWCATRGAVSVGRSERLSHPAQAMVWALGRVAALELPEL
WGGLVDLPESLDERAVARLAGVLSAEAGEAAEDQVAVRGSGVFARRLTRSAAPAADAATW
RARGTVLVTGGTGALGGQVARWLVRNGAEHLVLTSRRGLEAPGAPELREELEALGARVTV
AACDVADREQLAAVLAAVPEEYPLTAVVHAAGANAAGPLAETTVADAAAVISGKVAGAVN
LDALLGDRELDAFVVFSSIAGVWGSGGQAAYGAANAYLDALVEDRRGRGLAGTAVAWGPW
AEGGMAAADGGDQLARRGLPAMAPGLAIAALHGAVAGDEGVMTVADVDWERFAPAFTIGR
PSPLLGELPEVQRALANAGTAEGAGAAAGSALRERLTGLTEAEIDRTLLDLVRAHAAAVL
GFAGAEAVEPGRAFKELGFDSLTAVEFRNRLNAETGLVLPATLVFDYPSATVLADHLRAE
VLGTQGAVATPSAVVAAVDDDPIAIVGMSCRFPGGVRSPEELWNLVAAGTDAITDFPSDR
GWDVEGMYDPDPERLGTFYAREGGFLDGASEFDAAFFGISPREALAMDPQQRLLLETSWE
AFERAGIDPASVRGNQIGVYVGAATSGYGTGLHEIPEGLEGQLLTGSATSVVSGRISYTL
GLEGPALTVDTACSSSLVALHQAAQALRQGECDMALAGGVTVMTSPAAFVEFSRQRGLAP
DGRCKPFADAADGTGWSEGVGMLLVERLSDARRNGHQVLGIVRGSAVNQDGASNGLTAPN
GPSQQRVIRQALANAHLSPADIQVIEAHGTGTTLGDPIEAQALLATYGQERPENLPLWLG
SIKSNIGHTQAAAGVAGIIKMVMAMRHGVLPRSLHVDEPSRQVDWSAGEVRLLTEATEWP
ETGQPRRAGVSAFGVSGTNAHTIIEQAPPVEDEAEPAPAPADDHGMAPWTLSARSPEALR
AQAERLRTHLLEGAEHGVLDIAESLVATRSVFEHRAVLLGTERETLLRGLETVAAGDDAP
GIVQGQAANGGKTAFLFTGQGAQRLGMGRELYDDFPVFARALDEVCAHLDVLLDRPLKDV
MFAAEGGADAELLDQTAFTQPALFAIEVALYRLLEHWGVTPDVLIGHSIGEIAAAHVAGV
FSLEDACTLVAARGRLMQALPAGGAMVAIEVSEEEIAPSLAGRAAEVSMAAVNGPNAVVI
AGDEAAALEIAEQWAEQGRKTRRLRVSHAFHSPHMDAMLDDFRAVARTLAYNSPSIAFIS
NVTGEQAGADEVCSPEYWVRHVRETVRFLNGVRALEAQGVTAYIEVGPDGVLSALAQDCL
TEPADDIAAEDTPAPLLVPVLRKDRPEPQALVAALAEIHVHGETVDWRAFFAGRGARRVD
LPTYAFQHQRYWLEAGASVGDAAAFGLDPADHPLLGGAVPLAGADGLVFTGTLSLHTQPW
LADHVLRGEAVLATTALVELAVRAGDEVGLGHVEELVIQAPLALPRGGGVQIQLVLGEED
ETGTRSLEMYSRAAEPAGEDEWICHASGVLAPEPDDATSAEAVAGLAAWPPPGAERVEVD
GLYELLAGDGLVYGPSFRGLRAVWQRDDEVFAEVSLAEESVVDAQRFGLHPALLDAALQP
LGLGVLDGVGRGRMLFSLAGISLYASGASALRVRLARTGPETLSLTAVDGAGEAVVSADT
LTLRQVATEQPEAAPAADAAGTLPEPAASSEAAAETPVEETSAKPSRRRKTARRSAKRGG
PDSGPLTALRERLAGLSEPEQDRVLLDVIRTHVAAVLGHASADAVQGSQAFKDLGFSSLT
AVEFRNRVSKAIGLRLPATAVFDYPTPAELAKFTRAEVLGARTGEVRPVPVAVAGNDEPI
VIVGMSCRYPGEVATPEDLWNLVAEGRDGISPFPTDRGWDVENLYDPDPDEPGKCYTQEG
GFLHGASQFDPAFFGISPREALSMDPQHRLLLETSWEALERAGIDPVSAKGSQTGVFAGV
TYQDYGGVLAGSQDSVEGYIGTGVSPSVLSGRISYTLGLEGPAVTVDTACSSSLVALHLA
WQALRQGECSLALAGGVTVMSTPMSLVEFSRQRALASDGRSKPFSAAADGASWAEGVGML
VLERLSDARRNGHPILAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALANARLSAAEVD
AVEAHGTGTSLGDPIEAQALLATYGQERPEGQPLWLGAIKSNIGHSQAAAGVGGVIKMVM
AMRHGVLPKTLHIDEPSPMVDWTAGDVELLAEARPWPETGHPRRAGVSAFGMSGTNVHTI
LEQAPETEAAEAAEPAGTGAVDGPVAWVVSGKSGDALRDQADTLRKFVAERPELSAADVA
LSLATTRSAFQYRGAVTGTGREELLERLEAMAEGAKAPGVVRANAIEAPGRSVFVFPGQG
AQWVGMAVGLLESSPVFAEAIGECETALSAYVDWSLTEVLRGAEGAPGFDRVDVVQPVLF
AVMVSLAKLWRSVGVEPDAVMGHSQGEIAAACVAGALSLEDAAKVVTLRSQAIAVGLAGR
GGMVSVGLPVDRAKERIAAWDGAISVAAVNGPGSVVVSGDPGALDEMVAQLEGEEIQVRR
VPVDYASHSAHVEAIHDELLKVLADLKPRTSEVPFYSTVSGELVDTAGLDAEYWYRNLRQ
TVELEATTRTLLDTGHGVFIEVSPHPVLTLPVQQTVEAAEAQAVVIGTLRRDEGGPERFL
TSIAELHANGADVDWRKVFAGHGGRQVDLPTYAFQRQRYWPQPAEDGGLGNGPVSEADSV
DARFWEAVEREDLEGLAQTLELDGEAPLSAVLPALSSYRRGRRDRSTVDNWRYRINWKPL
IDQPSSGSEQERGAPITGTWMVVVPPVDAARELAERIARDVERHGARMVRVDLDATEPER
SSLTELLRAAAPGTSATDGSEQDGTPAVDGMLSLLALDEEALAGHPGVPRGFAGTVALVQ
ALADIDIDVPLWLATTGAVSVGRSDRVGSVKQSLVWGLGRVVGLEYAQRWGGLVDLPESP
DALDERALNRLVGLIGRSGDEDQVAVRASGVFARRLVRAPLGDARPARAWQPRGSVLITG
GTGALGGRLARWLVRGGAEHLVLTSRRGLDAPGAAELRDELTAMGARVTVAACDAADRGA
LRELLDGLPAEYPLTGVVHAAGVLDDGLIDTLTVPRTQGVFRPKVDAVVNLHELTRDLDL
SAFILFSSYAGTVGGAGQGSYAAANAFLDALAQQRRAQGLAATSVAWGAWGGGGLVDDAT
AAQLKRRGMPPLVPELAVDALQQALDHDEVDITVADVDWERYAPGFASARPRPLLNELPE
VRQALEAAEAELGAALSGLAVRLEGLSAAEREVEVLDLVRTHAAEVIGYPNADAVEPERA
FRDIGFDSLTAVELRNGLSAAAGVNLPVTMAFDYPTPTVLARFILGEVLGTAPAPADDLP
VVTGTVVDDDPIAIVSMSCRFPGGVRTPEDLWRLVSEGSDVISAYPTNRGWDLDDLYDPD
PENTGTSYASGGGFVYDADEFDPAFFGIAPREALTIDPQQRLLLETSWEAFERAGIDPAS
LKGSRTGVFAGSNGQDYIGLLLTAPGGPDGYLGTGNAGSVVSGRISYTFGLEGPALTVDT
ACSSSLVALHMAVQSLRQGECSMALAGGVTIMSTPGSFVDFSRQKGLSSDGRCKAFAASA
DGTGWGEGVGVLLLERLSDARRNGHPVMAIVRGSAVNQDGASNGLTAPNGPSQQRVIRQA
LASADLAAHQVHAVEAHGTGTRLGDPIEAQALLATYGQGRPEDQPLWLGSIKSNIGHTQA
AAGVAGIIKMVMAMREGVLPKTLHADEPTPHVDWTAGEVRLLTAPIAWPEDGEPRRAGIS
SFGISGTNAHTIIEQAPEPEEPEAVERAVTDAPSTGSRTLPWTVTGKGAEALRAQARNLH
DYVADHPELDLGDVGYSLAASRSVFDHRAVLLSGDRDALLSGLDAIASGATAPGVVQGSV
GTAGKTAFLFSGQGAQRLGMGRELYDDFPVFARALDEVCAYLDVLLDRPLRDVMFADEGG
ADAGLLDQTAFTQPALFAIEVALFRLLEHWGVTADVLIGHSVGEVAAAHVAGVLSLEDAC
ALIAARGRLMQALPEGGAMVAVQASEEEIAPSLIGRAAEVSIAAVNGPTAVVIAGDEAAA
LEIAEDWSEQGRKTRRLRVSHAFHSPRMDAMLDDFRKVVEGLSFQVPSISLVSNLTGAPA
GAEQVCSPEYWVRHVREAVRFADGVRALEKLGVTSFLEVGPDGVLTAMAQDCLTADEAGG
ALTLVPALRKNRPETQSLTTALAELHVHGTTVNWSTAFAGHDVRRVELPTYAFQRQRYWP
KAGGPMTGDVASVGLSSPNHPLLGAGVELAGSDGFLFTSRLSVQSQPWLADHAIAGAALF
PGTGFLELAIRAADQVGCGRVEEVTLATPMVLPENEQVQVQLWVDDADETGHRSLSLYSR
PADASSDEPWTQHAAGALAPAGPEPSFDLGTWPPADAEALDISDFYERFAASGFAYGPVF
QGLRAAWRSGDDVYVEVSLGEEHASLAADFGLHPALLDAAVQAVTFVALEDVGLSRLPFS
WSGVSLHAGGASTLRVRLTQLGPDSISLAVADGTGRPVASIESLVLRPVSVDHIDTARTS
AFRDSLFTLDWTPVPAIAPADTATATWAVVGTDHYGLATGSIAGAQVTAYADLDALGAAI
DGGAAAPEAVLVSYAPGLDDEAARSKPKSKAKSRAKGRSKAKRGLEPADAIHAVTHHTLG
MIQGWLGDRRFDSSRLVFVTSGAMAPEDHDETPDLIHAPLWGMVRSAQSENPNCFVLVDL
DPQEPAEASKAALPTVLATDEPQAVVREGTVLGQRMARVSSGTALLPPAGVREWRLDMHA
KGTLENLALLPSPDATEELGATEIRVALRAAGLNFRDVLNALGMYPGEAGPLGGEGAGVV
TEVGSAVKDLVPGDKVMGIFSGSFGPVAITDRRVVARVPESWTFEQAAATPIVFLTAYYA
MVDLAGLKAGQSVLVHSAAGGVGMATLQLARHLGAEVFGTASEGKWDTLRSLGLDDEHIA
SSRTLDFEKRFLDVTGGRGMDVVLDSLAREFVDAGLRLLPRGGRFLEMGKTDIRIPDEVA
AEYTGVSYQAFDLIEAGPDRINEMWNDLISLFENGVLRPLPVRTWDVRRAPDAFRFLSQA
RHTGKVALTMPRTLDGPGTVLITGGTGGLGALLARHLVVEHGARHLVLTSRRGAEAPGAA
ELVAELAGLGAVAEAVACDVADRASVASLLAGIGSERPLSAVVHAAGVLDDGVVESLTPE
RVDKVLRPKVDAALHLHELTRDLDLSAFILFSSVSGTFGGAGQANYAAGNAFMDALAQHR
RAAGLAAASLVWGPWTQDGGMTTELADADVTRMTRTGMVALTPEAGLALFDATRDLDGAV
LVPMTMDMSSVGEPVPALLRGLVRAPARRTAESAATSTTADPATALKQHLAGKSETERER
ILVDLVCDQVAVVLGYASGQAIEPGHAFKDLGFDSLSAVELRNRLNAITGTRLPATLVFD
YPTPASLARFLREEVTPADGPATEPVFGELDRLESTLSALESDSETHAQVMARLQGLVAK
WSAGGTGQVSGTATAVDDDLDDDSEIESATADEIFKLIDDEFGMS
>A0A2K8RJU7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. M56|TrEMBL
MHMIIVFKKWGDVVTLVCAGWIDGRRARTAPATLRLATTATRRTHRTSRTGDRPALAEGT
VLITGGTGVLGQELTRHLIAEHGVRHLVLAGRAATWRRSSPVSRT
>A0A5B7VA40|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. YIM 121038|TrEMBL
MSGPLPDPDGPQIEELARTPTLLHLAAIASSLVLYLVAGAQGLAGNVLIGHSTGELTALA
AADALAVSDAARVLCEREVALADGGFAGGLTAVRTGAQRAGHLCGATGGWTLMSSLFNAP
EQTVISGAVDELARLEKVTRAAGVQATRLLVVHPHHNPILALAAHRLAHVTVDYRLVEPA
TKVYSPLLGGFARKAGDVRRIIDRHLVDPVPYQQAIRALCADHGVGTFIEVGVHPILTEC
VRESLPPSVPLVGPLPGATDAKKILAVFPGSAAADGVQDTIPSAAVADPVPMQPSVPAMR
LSDDRPTGLALAAAPAELPTPLAAAAASGTRSPEREKLLSQLRRTFAEALGYPEGVSTED
THLEADLGIASVKKTELLAQLIDESDLSPCPPASVLVRDYTTLPRLADLMEHLAADEDAE
AERHECLAAGFRRADSPGDRWQTGHRAGRVARLRPPQRSRHRQLLPLRAGGRADPRRSGD
LWRFT
>A0A376SQ37|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Escherichia coli|TrEMBL
MDNAAIISGYSVWMPYAEDCSQLIDNLKQGKRVARTPWFTSNEEAIKCGFKGNPSVATLK
QVDDSALDLLSQLIDEALEQAMLDKHCLAGRNVRVYLTGIGPRIDGMDYKSFYNYNDVED
INLTQSITNLHASKMSQDTISSHLARKYRLQYLPPNMNCTSNSSLTAVHLATQGIEQGGI
DLAIVLNCSKIKTQDIWFLETQSMLDSEQVQPFGENSKGVAFAEGFSALLLESAHHRRAR
QQSEGVRVQTTYTQISAGRSNDASWLSTNVHKVMQAAMKQAEIALDDLAAILPHGNGSAV
SDNAEAKAIAMFAGERQIPVLAYKGQIGYTATGSGVVDLIIGHHSLTHHQLIAPVGNDVI
IDSMASLVLTDGSVTNHSKRHLLKVGVGVDGSVIGVVMTNMQAGRAK
>A0A2J7Y679|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pseudomonas putida|TrEMBL
MIKRRKVAIVGCAYRFPGSSNAGFWQNLMEGRDLVTQVDPSRWNKREFLHPDKASPATSY
TFASGTLGDISAFDAGFFSISPREAAMMDPQQRMLLEMCWETFENAGVKPSSLRGSNCGV
YLGIAGVEQSYRLLEDLSAIDGATATGNTMSIAANRLSFFYDLRGPSMAIDTACSSSLVA
FHQACQAILSGDVDQAVTGGISLHMHPFGFMIFAKATMLSRTGRCQSFDENGDGYARSEG
GGLFLLKDYDQAVADGNTILAVVAASAVNTDGRKSSLTLPNAEAQAALLKRAYTQAGIAP
EQLDYLEAHGTGTAVGDPIETRAIGEALGQARGAGNPLPIGSVKSNLGHLEAASGVAGLM
KALNCLAERTVPATIGVQALNPNIAFADLNLQVVTEPLPLKADGQLTVGVNSFGFGGANA
HVILQSPEPQAPAAQAPSARRVPLLLSAKSEEGLRATAERFAAYLAGQPQADYYDVAYQA
MFRRDAHSHRLLLVCDTAAEAAQALDDYAQDPTLSELSAVLEAGQALDGASAPVFVYSGN
GSQWQGMGRAMLDQPLFAAAVDEVDALFQPLAGYSLRAELLGDNGEGRYARTEIAQPALF
ALQVAVTQVLAAEGIHPVAVIGHSVGEVAAAWASGALSLEDATQVIYHRSRLQGLTRGTG
KMTAVGLSGEATAQLIAELKLDGRLVVAGENSARGATVAGEVDALALLEAALEERQVFAR
RLDLDYAFHSPAMDPIKQAVIDDLAHIRPQATKIPFYSTVVGGQLNGERLDSQYWWQNIR
FPVLFQGALAALVRNGLNLFVEVGPHAILRSYVSDVLVECEQPGQVIGTLKRNDHSPLLL
ERTVARLQIAAVEPQWQARFPVAGRPLRLPNYAWQRDHFSLPVTAEAYGPLSHERVHPLL
GYPVTDQALTWESRLDTQQYPTLADHKVGESVLFPGAGFTELALAVAQLHQPGEFVDIEE
LEIHNPLLLSSEVSKKVRVQVEEADGTLRISSRTLMQREDWVQHVVARLPGEARGVLLDT
RAPALPARPADFTGEQHLAMTCAVGLNYGPAYQTVAAAWVEGARVLAQLVVPAAIEHELA
SLHLHPALLDGAFQLITELLASRQGHDDGLAFIPVKLGRIAFTNAGGVPVLAEVRQRKRT
AHSLLVDFTLFDASGAAVLAIKDARMRAVRLQYDRSGDIKRMAHVGQAAPGAVVPVQRNA
VACSPLAEALQCLADEPAQVRYLNEVEPLLDVLCSSFVLDAVEQAGGRISAEQVAQWSQG
QGDFLAMLLRYAEHDGGLQRSADGGWQLVDQGERPTSQAIWQELFRSYTSQAIWQELFKS
YPEYFQIIHSVGRIGRHLSALLDGSQAFDTLLPRETSGASLARLVLGAAGQQHLLSGIGQ
TLAARLAQLPPGQRLRVLEFGFGGASFAELLYAGLDFDRLDYAYCVAEPELEQRLRDDCP
ALEVLGLEQLAEAGTFDWVLVPTDFGPLGTVGDALRLASGRLNPHGQLALLGQYPARWAD
FVFGAQPDWWLAGPQQALSRQQGPAFWSHELQRHGLTALRTLEALPGNACGSYLLLADKP
AGADTAAPVAVQRWAVLAEAGQGAALRLAQQLRAQGQQVDLLQPGDAQALAAQLGAFAQP
PEHVLHLAGFDSGTGLDGQAERCMQAAALVQACESLTIAPQCWLFSRGAAEHLYSVDTAA
EVAAIGDAALWGFGRTLANESPHCRIRLLDLAHAAAVELAVPALLHADSETELALDAEGR
RYVPRLRVLADQPRRAVGDAQWVCLGFDLPGQLRNLRWEVREPRQPAADELDIQVRATGL
NFRDVMFALGLLSDEAIENGFSGPTLGFEFAGVVQGKGAEAVGDFAPGDRVVGFGPCSFA
NRLVTNANAVARIPEGMSFEAAATIPSTFFTVYYALHHLARLEPGEKVLIHGAAGGVGIA
AIQIAKWLGAEIHATAGSDEKRDFLRLLGVSHIYDSRSLAYADQVLAATGGRGVDVVLNS
LAGEAINRNLQVLKPFGRFLELGKRDFYQNTRIGLRPFRNNISYFGIDADQLMSERPALT
RRLFAEMMELFEQGILHPLPFREFDANQVVEAYRYMQQARQIGKVVVTYANPIQQTVDTR
VQPVRALQLAADASYLVTGGLGGFGLRTAQWLIDKGARHLVLLGRRGPASEEAQPQLALW
YAQGIDVQAVACDITDREQLRGVFDRIAASPWPLRGLVHAATVIDDSLIRNLDGDQLCRV
LEPKAKGAQYLHELTQGLALDFFVMFSSATTLFGNPGQANYVAANHWLEALARYRRAQGQ
SATAVLWGAIDDVGFLARNSQIKDALQSRMGGSALRAEAALAQLEAMLLQGDNGHGVLEL
DFKALARFLPSATTPRFSELARAYGGDHEDEGGGEDIQRMLEELDDGELLERFVDMLKHE
VCEILRLPPARLDAQRPLQEMGLDSLMSVELVVALEERFGIRLPVMELSDSSSIDKLAAR
LLELLRGEASSGEEQLAQNVLARHGSEHSAEELAQLNAALADSNAAPNRLID
>G0PUE3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MSEEQKLRDYLGRVTAQLKQAKRTLQNLEAAQNEPIAIVGMACRYPGGVRSPEDLWRLVD
SGEDAISEFPANRGWDLDALFDTDPDRSGTSYTREGGFLYDADEFDADFFGVSPREATAT
DPQQRLLLESAWQVLESAAIRPDSLRGSDTGVFVGVMSQEYGPSLLHPSVDGTDGFLLTG
NQNSVASGRIAYTLGFEGPAVTVDTACSSSLVGVHLAVQALRAGECSLALAGGVAVMSTP
GFFIEFSRQRGLSPDGRSKSFAAAANGTGWSEGVGMLALARLSDAERLGYRVLGLVRGSA
INQDGKSSQLSAPNGPAQQRVMRQALASARLTASDVDVVEAHGTGTVLGDPIEAQAVIAT
YGQDRESPLWLGSLKSNIGHTQAAAGVGGIIKMIMAMRHGVLPRTLHVDEPTPHVDWSAG
SVELLTKARPWPELERPRRAGVSSFGISGTNAHVVLEAVPVAEPAEPGESVEPGGAARVP
YLVSARTPDALRAQIDRLRHHLDRHPGLSPADVGFSLAERTQFTHRAALLGDATLAEGQA
GRGGLAFLFTGQGSQRAGMGRELYETYPVFREALDAALTALGIQDEFFTGDLDRTRLTQP
ALFALETALYRLYESWGITPDHLVGHSIGEITAAHVAGILTLPDAAKLVTARATLMDALP
HTGTMTAIEATEEEITPHLDDTVGIAAVNGPTSVVISGDTDATERITEHFRTQGRRTKAL
TVSHAFHSHHMEPMLDDFRTVAHTLTYTPPRIPIVSTVAADSDLTDPDYWVTQIRAAVRF
HHAVVELANHGTTTFIELGPDGVLTAQAQQSADGVFAAALRSSQDEVTSTLTALGTAYTH
GRVPDAQALYGDAHRVELPSYAFQRQRYWLTAGVTSADATDLGQTPADHPLLSSVVRPAD
SDTVLFTGRLTPGTWLDDHTVLGTAIVPGAALVDLALHAAGESGFATLDELVVEAQMVLT
EALQVQVKVVDDSVTIHSRTDGDWTLHATGTLSNDTVPRADLAWPPVAEPIDVAEMYAEL
GAAGLAYGPAFRNVTAAWRTAAAVFAEVAVEKHDFGVHPALLDAALHPLAATADGLALPF
AWQGVRLHSPGATALRVRVDLGTNAVHAVDAEGAPVLTVSSLATRPVTADQLATRTDGLY
ERTWVPVTPVPVPHTVLDVPDGTVHDVTARVLSALQEKLAGDGTVAVVRRGDDLSAAAVE
GLVRSAQAEHPGRIVLVDTDGSVDLATVVGDEPHVSVRAGAVLAPRLARSTGRGPAPTWG
GTVLITGGTLGTLLARHLVERHGVRDVVLASRSGRDPGMAHVRGVACDVTDREALKALLD
GLPDLAAVVHTAGVLDDGPIDTLTPQRLDAVLRPKTAAWHLHDLTRERDLKAFVLYSSVA
GTFGTAGQANYAAANSYLDALARLRHREGLPAVSLAWGMWDDGMASELSDADRARLAREG
FLPITAEHGLAMLDTALGLDVPTLVASPLNLAAFRDEAPALLRGLVRTTRRAVPAGDLAD
RVTGLSEDEQRAVVLDVVRENVAAVLGHTDPGAIDADAQFGALGFDSLMSIELRNKLSAA
TGTKLSGTVIFDHPTPDALAEFVRVTLTGSRVVRAAAVATTAVTDDPIAVVGMACRFPGG
VTSPEDLWRLVADGVDAIGEFPADRGWPDLYHPDAERTGTSYVKHGGFLYEADAFDPEFF
GISPREATAMDPQHRLLLETAWHALEGTGIAPASLRGSRTGVYTGLMHYDYAPRVGQYAA
AMEGFVSTSSAASVASGRISYTLGLEGPAVTIDTACSSSITATHLAAQALRTGEVSLALA
GGATVMANPDVFVEFSRQRGLAQDGRSKPFSADADGTSWSEGAGVLVLERLSDAVRNGHT
VHAVIRGSAVNQDGASNGLTAPNGPSQERVILQALANANLESADVDVVEAHGTGTTLGDP
IEAQALLATYGQGRPANRPLHLGSLKSNIGHTQAAAGVGGIIKMIMAMRHGTLPRTLHVS
QPTPHVDWTTGAVTLLTENQPWPDTDRPRRAAVSSFGISGTNAHLILEQPTPTPATPATT
EPIPYPVSAKTPQALQAQITALQHHLTEHPDLAPADIAHTLNHRTQFDHRALLLGTEVLA
SGAVGSGGLAFLFTGQGSQRTGMGRELYETYPVFREALDAALTALGIQDEFFTGDLDRTR
LTQPALFALETALYRLYESWGITPDHLVGHSIGEITAAHVAGILTLPDAARLVTARATLM
DALPHTGTMTAIEATEEEITPHLDDTVGIAAINGPRSIVISGDDTAGVAARFPDRRTKKL
IVSHAFHSHHMDAMLDDFRVTAEQLTYEQPSIPIVPTVATDLAMTDPEYWVTQIRSAVRF
HHAVVELENRGVTTFIELGPDGVLTAQAQQSAEGTFTAALRRDRDETTTALTALGTAYVH
GRTLTTPHGAQLSDLPGYAFQRQSYWLTRTSGNAAGLGVGASGHPLLGGLLRLADGESTD
GESTVLTGRLSPSSWLADHQVRGTVVVPGTALVDLALHAGELAGLSTLDELVIEAPMLLT
EALQVQVKVVDDTVTIHSRTDADWTLHATGTLGSTPVTPQEFTWPQGQELDTSGIYAMLA
DLGLDYGPVFQGLTRAWRDGEVLYAEVEVPEHGFGLHPALLDAALHPFAATADTLALPFS
WNGVTLYATGATTLRVRITPSDEGLALHAVDPSGQPVLTVDRLVTRPVGAELTARTDGLF
QLSWPQVTPTTRTTEHTLIEVPAGNVHDVTEHILTTLQTHLTDTTDNHLIILTRNAVNTP
TPDLAAAAVWGLVRTAQTEHPDRITLIDTDDTLDPTTLTGNEPQLTIRNGKTHAPRLTKT
PTPQPPTWHPDDTVLITGGTGTLGTILTRHLIETHHIRNIILVSRQGKTPHTLTDLNANI
TTTACDTTNREALHQLITNTPNLTAVIHTAGIVDDALLTNLTPQQLHTVLATKTDTAHHL
HELTQHLNLKAFVLYSSLAGTLGNPGQANYAAANAYLDALAQHRHTQGLPATSIAWGLWA
NTSGTTQHLTTTDHARLTRDGITPITTEHGTALFDAALGLNTPTTIATPLNLTTISKNPT
THPLLRNLIPRRTPTTTVRQEDSRAFGASLVGLDEAEQQARVLDLVRSQVAAVLGHNDAG
AIPPDIAFEQLGFDSLTAVELRNQLTRATGVQLSATLVFDHPTATALAGHLRDTLAPSGR
KAARAKLDEVAALLSTLVVEADDHSLITEHIEDLLAQWRGTGDGPASPADDSDLNAASDE
ELFSLVESNRKA
>G0Q190|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MSGRFAGSDDLDELWTHLANGDDLITEANRWDLPATGPDGSARCTQGGFLDGIDRFDPVF
FGISGVEAAVMDPQQRLLLEEAWKALEDAGHAGRQLGGTRCGVYAGCWNGDYHELVGEDS
PAQAFWGNMASLIPARISYVLDLKGPALAVDTACSSSLVAIDLACRGLRSGETDMALAGG
VFVQTTPRLYELAGRAGMLSPTGRCHTFDHRADGFVPGEGVGVLVLKRLRDAIADGDHVH
GVIRATGTNHDGATNGITAPSSVSQEALLREVHASCGIDAGSIQLLEAHGTGTPLGDPIE
FSALSRVFRAGTERTGFCALGSVKSSLGHTQFAAGIAGVFKILLAMRHRQIPASPHFEKP
NAAIDLDTSPFSLSTRHRTWEAPSDGGPRRGAVSSFGASGTNAHLVIEEAPDTSRTRTRT
PGPARLVVLSAHSREQLADQVSRLAGHLRHGDAPDLGDLAYTLTVGRDRFPHRFACVARD
RAELLRILDAGLDGPEAFTGRATPEGQGRPGADTSRGEACLERRARYAADATEAEEHGAR
ASGVRADASRAGAEHRRPDADACRADLTVLAECFVRGAALDYGAIFPAGSHRRIPLPTYP
FARESHWAGPPPPAPLPVPGTPGKRPAAAHPLIHRTTEAPDSPGALRASAVFTDADPVLR
DHTVRGQHVLPGVVHLELARQTAVRLWGADATAPLLMRDITWVRPATARDGEPLDIDILV
RPGDEDRLTFEITTRADRGADPTVLSTGRVYRTGTTRPGRVDLTSLRAACTTTVSATRVR
EALASMGIVHGPSLRAVREAYVDTGTGTVLAELELPAGASPADGGPVLPPALLDSAIQAS
IALHLGDGPADPETAVPFALDRFELLAPCPSTARAVVRVADATAPATALSRLDVDITDVH
GRVCVRMTGYTSRRLRPPVPSLFAPVWKSVAARTPDGHAPDPADHMLVVGGTAEQRAALL
GRHPGATPWDLAPGTTTEEIAARLRSAGPVGHLVWIAPGPGPDGGPALTPTDTAGFAAAQ
EDGVVAAFRTAKALVRTGHDARPLRITLVTRRALATYDDEPTAPAHAGLHGFFGSLAQEY
ANWSVRRADLDTDELPHDLLALPGRTGDDPLAHRAGQWLARRWAPDEPGDAQPAPYRRGG
VYVVIGGAGGLGTQWTRHVVRNHDAHVIWIGRRPADASIDARLAEAGARVSYLSADAADP
ASLRLAHKEIKRRHPRIHGVVHAALDLRDRSLARMDEGTLRASLAAKAGVGVAMAEVFAD
EPLDFALFFSSVQSFTTAAGQSNYAAGCTFGDAYAHFLDRHWPCPVKVMNWGWWGSVGSA
STERHKEHMARWGLLSIEAPEAMDALDTLLGGPQRQLSFIRLKDLDAIEALDPATRVTVH
PRARTRVAPALVASAAALPAGWESIRAIAAWRADERDPLLAKMVRGHLQALGGLRGTGTP
TSPGDIDRLRRNAGILDRYATWLDHALRIVPETAPPPDVLLREWDERRAHWSTDPDKAAE
LALLDATLRALPGILTGATRPTDILFPRGSVELVEGTYRDNRVADLYNRAMTDAAVSVVE
ERLRLDPSARLRILEIGAGTGGTSVGMFAALRPFQEHIEVYTYTDLSRAFLNHARSAYGP
DVPYLSYARFDAERPLAGQQGVESGSYDLVVAANVLHATRDTRNTIRNAKAALRHGGWLL
LNELAAFDVSSHLTFGLLEGWWLFEDDALRIPGSPALSPENWRRVLESEGFTAVVPVLPE
ARELGQQIIAAESDGLARQSVAPRTGRGPEPRKPGRRRPAGREAGDRPAARREATAPAAV
DSSSPAVAGAVPRRAAHVPTPAPVPAFVQVPAQPLDAGGGVAPSAAGTVSRTEVLSGYLR
DRAAETLGIPADRIALTTPLSDYGMDSILVLQLTNALREDLGEVSSTLIFDAESVAELAD
HFAASGGPRVDVLVARRNPDTGERPAPGPAPRPSADAPRSVASLFRTVLETGTPQQAGDL
LAMAARLRPVFAAGAGDEPEVLRLSDGRREPDLVCLPSLIAPTGAHQYVNFAGALRGRRQ
VWAASLPGYRAGEPLPADLEAAAERLAATLLRRFGGGGFALAGYSSGGWLAHEVVRRLEA
AGAPPAGLVLLDTPRTTGAAMVGGMTVITRRLLDRFPRLPLADEQVTAMARYGELLDGWR
PLPVTTPTLLAAAAQEGPLRELLGDDARSGWPLEHRRADLAGDHFSLLEEDAAETAFTVD
RWLDTLRDPAGGTR
>G3J044|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Methylobacter tundripaludum (strain ATCC BAA-1195 / DSM 17260 / SV96)|TrEMBL
MTTNSETGQAQRNLIKSALLKIDELQARLKACNAEKNEAIAIVGMGCRFPGGVDSPEAFW
QLLNDGRDAITEVPPERWDIDAYYDADPDAPGKMNTRFGGFIERVDQFDARFFAISPREA
VSMDPQQRLLLEVAWEALEYANIPPDSVYGSATGVFVGIIGQDYAQRLFAPGYLDKIDAY
VGTGASQGVAAGRLSYALGLTGPSFSVDTACSSSLVTLHLACESLRRKECDLALSGGVNL
ILEPGLNVNFSKARMMAPDGRCKSFDSAADGYVRGEGCGMLVLKRLSDALAAGDQVLAVV
RGSAVNQDGPSGGLTVPSGPSQEQVVRQALSNAGITPDAVSYVEAHGTGTALGDPIELGA
LDAVFSASHSAANPLYLGSVKTNVGHLEAAAGVAGIIKLVLALRHDSLPRHLHCDNPTAR
FAWADKPLRVLHEPQAWPRGERPRIAGISSFGFSGTNAHIVIEEAPQPLRTQADESATRS
GSAAIAASAQQLLVLSARSDVALLALAQRYRDYLRAHPDTAPADLCGSAATGRSHFLHRL
ALSAASAAGFAEGLEAFIDGNAAASRVSHKIPGAAAPALAFLFTGQGAQYPGMGQRLYQT
QPVFRRAIDRCAELLQPWCDVPLCELLFDTAADRLDQTGYTQPALFCLEYALSELWQAQG
VRPDAVVGHSVGEYVAACVAGVFNLDDALKLLAARARLMQALPTGGAMAAVFAGEARVAQ
ALAGHDRLAIAAVNGAENVVISGDETALNHVLDELQAENIGHRRLSVSHAFHSPLMEPML
AEFAKIAAEIHYHAPSLPLISNVTGRLIGEDIATPAYWVEHIRRPVRFADSIDTLHDRHC
RLFLELGPHPVLLGMARHISPDAILIPSLRQQTADDEQFLRSLGDLFVQGVAIDWNAVYP
KQTYRPLHLPTYPFQRQRFWVDRASSSANEIGRTARADTKHPLLGQRLRLPAMPKGEIRY
EQTLNDKGYIQDHRVFHQSVLPAAAYIEMGLAAASKDSDTALPGLEDITIQQALVFSENR
DKTVQLVLTQATEQPARFEIYSLSDNEPEQWIFHVAGNIAAIAPIVAPPAVDMKTIEAEF
EEEIAIEAFYRQCEQRGIDYGPDFQALQSLRRSEGRALGSIRLPERLVAETAHYHIHPVL
LDACFQVLIATLSDSSANETWLPIGLDRLQLYRAPGNRLWCRVQVHKATEQPLLKADLSL
FDDRGEIIGIIEGFKAKQAAPDNLLSAKSDLETWLYGVDWRAQGLCSPHANAALLASPTS
MSDTLNASMAAWVRQSRLEECGIALDELDQLCVDYALAAFRDMGKTFQPEDGFSTLEIAD
NLGIMPAHRHLLERTLEMLAEAGFLQRTGTGWEVLRAPAIPHPQQTAQLLRARYPQIGLE
LDLVERCGSALARVLQGRCDPLQELLFPGGDGSALAALYRDPPGAQAVGAVFKQALLSAL
ESLPQRSGIRILEIGAGTGGASSFLLPHLPTNRTEYVFTDISPAFTLQAQTTFAAYPFIE
YKTLDIEKDPQAQGFKRHDYDIIVASNVLHATEDLAQTLKHTRSLLAPGGLLLLLEGTAP
QNWIDIIFGMTSGWWRFSDKHLRPSHPLLSGQSWCDALHASGFQQTGCIDCAPIHQSIIM
AQADALPVDASPTQPWLIFADADGTGQRLGEYLRAAGSACTLVYPGSQYRRTQQDSFTID
PYQASHYQRLFSELGDAGVAYCAHLWSLDTPTPSDGALSLTENARLGWETVLHLVQALGK
ARPSNPPRLALLTRGAVSVTGEALTGLAASPLWGLGKSIALEHPELRCIRIDLAAGARPD
EIPAIVAEMTADARAQVEDQIAFRDERRLVPRLVRRGGKQSLPQTESYQLGVPASGSLDE
MAWNPTERHAPRAGEVEIRVHAAGLNFKDVLLALHRVPAAGPVLGIECAGVVARVGSGVS
HLSVGDKVLAMAPGSFSRYVNASACTVVALPENLSFEEAATLPIAFLTAAYALEDLAKLQ
AGERVLIHAAAGGVGQAAIQLAQRAGAEVFATASESKWDVLRALGVKHIMNSRTLDFADE
IRRLTDGEGVDVVLNTLSGEFTSQSLALLRSGGRFLEIGITDLRTPEEIAELAPGIAYHA
IDLMHLYQEKPTLLQALLQRLMGEFRNGQLKPLPRTVFAANDAQTAFRNMQQANHTGKLV
LSFDTAALPFRKDASYLISGGLGDLGLLVAAWMAEHGAGHLVLAGRRGVTPATEAKIRAI
TQAGAEVSIFQVDISKPEQTARMLAEIEQTLPPLCGIMHAAGVLDDGVLIEQTPERYTKV
LEPKLDGAWQLHIQTQALPLEFFIMFSSATSLLGSVGQSNHVSANAFLDALAGDRLAHGL
PALSINWGAWSEIGYAARVQAGDFLKAQGMGTIDPRAGLAALERIFHCDKAQVGVVPIDW
PTYLQRIASSGYLADFRREFSSAQSAPSEQPAEFRRLLESAPVDERLALLTRHVASQVAT
VLGFPASMTVDRKQGFFDMGMDSLTSVELRNRLRTSLGCALPSTLAFDFPSVTALVDYLA
EDLLGREPIDPSPQTETGENAERKALEQLTEEEAEASLLKELEDMGFSL
>G0Q008|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MSRIAIVGVSCSYPDATTPRELWENAVAGRRAFRRLPDVRMRLDDYYDPDPAVPDKFYAR
NAAVLEGWEFDRVAHRIAGGTYRSTDLTHWLALDTATRALADAGFPAGEGLPRERTGVVV
GNTLTGEFARANVMRLRWPYVRRVLADALKGQDWGDERLGEFLEGVEDAYKQPFPAIDED
TLAGGLSNTIAGRICNHFDLNGGGYTVDGACSSSLLSVTTASASLLNGDLDVAVAGGVDM
SIDPFEIIGFAKTGALARTEMRLYDRGSNGFWPGEGCGMVVLMREEDALAAGHRVYASIA
GWGISSDGQGGITRPEVSGYQLALARAYERAGFGIDTVPLFEGHGTGTAVGDATELRAIM
GARAQADPHAPSAAISSVKGMIGHTKAAAGIAGLIKATMALDAAMLPPAIGCVDPHELLT
EESANLRVLRRAEAWPSGAPLRAGITAMGFGGINTHVVLDRALPTGRRTLSRRSTTLANS
LQDAELLLLDAASPQALRERLSQVADFAVKVSYAQLADLAATLQRELRELPHRAAVVVTS
PEDAEVRLRRLAQVPNTDGSITLSPDGRAFIGRAKDAARIGFLFPGQGSGTSTGGGALAR
RFTEAADVYRRAGLPTTGDMVATDVAQPRIVTGSTAGLRVLDALGIEADIAVGHSLGELS
ALHWAGALDSTTLLEAARVRGAAMAEHSASGTMASLAATPEEAGELIADLPVVVSGYNGP
RQTVVAGTVEAIATVSERAERAGVSCTGLAVSHAFHSPLVAPAADAFGDWLAGERLAEVD
RRVVSTVTGEDLESDTDLSKLLRQQITDPVLFTQAVRSAAPDVDLFVEVGPGRVLTGMAA
ATADVPAVALNTDDESLRGLLQVVGAAYVLGAPLIHERLFNDRLTRPLEVGAEFSFLASP
CEQAPDVALPATRAPRAEGSGDGATERAGGSAGESALDVLRALVAERAELPPELVDDSSN
LLDDLHMSSITVGQIVNQAAVQLGLTAAHVPTNFATATMAELAEALTTLAGTDDGDAPAP
VVAGAAAWARPFAVDLDEVLLPAPVSGGDNGSWELFTAQDHPFAQDVRSALEKAAVGSGV
LVCLPPDCSREQIEHALEGAKAALAGDRERRFVLVQHGRGAAGLAKTLHLEASHLRTTVV
HTPVCDGAAERVAAEVAATARFSEVHLAADGTRRVPVLRALPIRAERTEQVLGDSDVLLV
TGGGKGITAECALAVARQTGVKLAVLGRSDPARDEDLAANLRRMADSGATVRYARADVTD
PVRVAAAIAELTDALGPVTAVLHGAGRNEPASLTGLGMDDFHATFAPKVDGLDVVLDAVG
EGNLKLLVTFGSIIGRSGLRGEAHYATANEWLADRTEQVARDHPGCRALCMEWSVWSGIG
MGEKLSVVESLSREGIVPVSPDQGVEILLRLISDPDAPVVTVISGRTEGIGTVRRDLPPM
PLLRFTGTPLVRYHGVELVTEAELNAGTDLYLADHLLDDNLLMPAVIGMEAMVQVASALT
GRADVPVIEGARFLRPIVVPPAGTTRIRIAATVTDTDTVDVAVHAEDTGFVAEHFRARLV
YSGAAVPDGPPAQVGPDVPPAPLDPAADLYGGFLFQGERFQRLRRFRRAAARHVDADVAI
AAPSGWFAGFLPDTLLLADPGMRDALMHGNQVCVPDATLLPSGIERLYPMPAGGDLPREV
RYCATERHRDGDTYVYDIAVRTADGTAVERWEGLTLHAVRKTDGSGPWVAPLLGPYLERA
VEEVLGTHLDIAVEPDLPGAGESADERRAATARAVQRALGESAEVRYRPDGRPELVGGRE
ISAAHGLGVTLGVAAAGTVACDIEAVCVRDADTWAGLLGEHAGLAAQVVKQTGEAPDTAA
TRVWGAVECLRKAGLMAGAPLTLTPPNRDNWVVLASGGLRIATFVTTLRDALEPAVVAFL
APIPDASAPVPASSAAGRRPPTGRQT
>G0Q9T7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MPATSPNEEKLRDYLKRVTADLRQARQRLSAAEARNREPIAIVGMACRFPGGIGSPEDLW
RMVADGAEGISELPTDRGWDLDALFDADPLRAGTSYIRGGGFLHGAAEFDAGFFGISPRE
ALAMDPQQRLLLETAWETVERAGIVPAALRGENVGVFVGAVPQDYAPRHGDPAAEDVEGY
LAVGNTTSVMSGRVAYTLGLRGPAVTVDTACSSSLVALHLAVQALRQGECTMALAGGVTV
MAAPNWIVDLSRQQGLAPDGRCKAFAEGADGFGPAEGVGLLLVERLSDALRNGHRVLAVV
RGSAVNQDGASNGLTAPNDEAQEDVIVRALANAGVSPRDVDAVEAHGTGTRLGDPIEAQA
LLATYGQGREEGAALLLGSLKSNIGHAQAAAGVAGVIKMVMAMRHGVLPRTLHVDEPSSH
VDWSAGDVSLLTESREWPETGRPRRAGVSSFGISGTNAHVILEQAPRPDAPDEAEPGAVS
ESMPEPTPESASGTTAPSPAVPWTLSARTAEGLREQAARLLAHVEEHTGTRPADVGHSLL
ATRSLWDHRAVVVGTDDTSLRTALAAAAAGEPGVVSGVAGAGARPVFVFPGQGAQWSRMG
LELADAFPVFDDALRECAAALAPFVGWDLRVELAGGLGRVDVVQPASWAVMVSLARLWES
FGVVPAAVVGHSQGEIAAAVVAGALSLEDGARIVAERSRVIGERLAGRGGMASVALPAET
VRERVAGFGDRLAVAAVNGPSSTVVSGEPAALDELLVALEGEEVRVRRIAVDYASHSSHV
ESIREELLNVLAPIVPRSSTVPFYSTVTGGLLDTEQLDAAYWVRNLRQTVEFEATTRALI
ADGLSAFVECSAHPVLAVGVEESGASTVVGSLRREDGGAQRFVTSLAQAFVNGLPVDLAP
LVADGRAVDLPTYAFQGTHYWLRPTAGRTDFNAAGLGAAHHPLLGAVVRLADTDGALLTG
RLSLADHPWLADHTVDGHVILPGAAYVELAVRAGDEVGCGRLAELTLQAPLELVDGRPVA
VQVAVGTAEADGSRPLTVHARRDDSGDASWTCHATGTLVPADAAEPSFGLTAWPPPGASA
VPVDTFYDDVTAAGYGYGPAFQGLRAVWTAGDEVYAEVTSVAPEEAERFLLHPAALDAAL
HAILVRTGDAGDTAALRLPFSWSGVEVYATGTADLRVQLTRTGDDTVSVRLTDTDGTPVA
RVESLALRAPATDTLGTKGAADLLHVVWEPIVGLPAPTDAADIVFLDTGAPDLDTVATPD
GPAPDVVALALPDDATDVRDLVGSVLALVRRWLSDDRWSTSRLAFVTRRDSLAHAAVRGF
VRSAQTEHPGRFQLLETERDSEPSPDAVAAALATGEPQLALGPTGVSTPRLAPVPADPDT
TSTPIDTEGTVLVTGGTGTLGSLLARHLVTAHGVRHLLLLSRGGPDAPGAPELVADLAAH
GADAHIVACDAADRDALAAVLADIDPAHPLTAVVHTAGALADTVVTSLTDDHVDQVLRPK
SDAAQHLHDLTAHLGLSAFVFFSSAAGVLGTAGQANYAAANAYLDALAVRRRQDGLPAVS
LAWGYWEQASGLTGHLDRGDVLRLARTGVAPMTTAQGLALFDAGLRTPHPAVVPLVLDRA
ALRDAARSETLSPLLRTYAPRPRRRTTTAGAARGASAVSDLARALVGLTPEQREHTLTEL
VRAQAGAVLGHDSAAAVDAGQPFRALGFDSLAAVELRNRLNTATGLRLPATAVFDHPTPD
RLAAHIGTLLDGGPEARTQPSAPGGPGAARASAVDEPIAIVGMACRLPGGVGSPEELWQL
VADGVDAVSPFPTDRGWDMDALLGATDGTGGTSYVREGGFLYDAADFDAGFFGISPREAL
AMDPQQRLLLETSWEALERAGIDPTSLNGTRTGVFTGVMYHDYASRLDRVPEEVGGYLAT
GTSGSVASGRVAYTLGLEGPAVTVDTACSSSLVALHLAAQALRQGECTMALAGGVTVLSS
PSVFSEFSRQQGLATDGRCKSFADAADGTGWAEGVGVLLVERLSDARRNGHRVLAVVRGS
AVNQDGASNGLTAPNGPAQQRVIRQALESARLSPTDVDAVEAHGTGTRLGDPIEAQALLA
TYGQGREGGDALLLGSLKSNIGHAQAAAGVAGVIKMVMAMRHGVLPRTLHVDEPSSHVDW
SAGDVSLLTESREWPETGRPRRAGVSSFGVSGTNAHVILEAVEHTDAPAHSTPAVGGGAT
PWVLSAASEDALRATAERLRTHLQSVTDADQDLLSVAGALLRSRARLEHRAVVVGHDREE
LLAGLYAVAAGEPGVVSGVAGAGARPVFVFPGQGAQWSRMGLELADAFPVFDDALRECAA
ALAPFVGWDLRVELAGGLGRVDVVQPASWAVMVSLARLWESFGVSPAAVVGHSQGEIAAA
VVAGALSLEDGARIVAERSRVIGERLAGRGGMASVALPAETVRARIEGFGERLAVAAVNG
PSSTVVSGEPTALDELLAALEGEEVRVRRIAVDYASHSSHVESIREELLDVLAPIVPRSA
TVPFYSTVTGGLLDTEQLDAAYWVRNLRQTVEFEATTRALIADGLSAFVECSAHPVLAVG
VEESGASTVVGSLRREDGGAQRFVTSLAQAFVNGLPVDFGPLTQASDVMDLPTYPFQRSR
FWLESGELPASAGVPRDEVEDRFWEAVEREDLESLADSLDLDGEELRPLLPALASWRRAG
RQESVIDSWRYKTAWRPVSGTSVPVLSGTWIVVVPESAGDDDTTASLVRMLGARGADAVT
LTVTEEDADRTRLAGRVQEALAGRHDLRGVLSLWAFDEKPTENQPLVSAGLAGTVSLVQA
LRDLDATAPLWCLTRGAVATAPSETLTSAVQAQVWGVGRVAALEQSGVWGGLVDLPDTPD
ERALRRLCGILAEPAGEDQLAVRAGGVVARRMVRASLGRTAPARRWAPDGTVLITGGLGA
LGAHVARWLAREGAPHLVLTSRRGGDAPGADDLARELTGLGARVTVAACDIADRDAVEAL
VTGLADQGGPVRAVMHAAVQAELAPLAHATPDHFAALLGAKVAGAEHLDSLLGEDVDAFV
LFSSIAGFWGSGDHAAYAAANAHLDALAERRRARGLAATSIAWGIWDAYNDWDSLSATER
RTITDRAVQQGLPLLDPEAACTGLRQALDHDETFVAIADIAWEPFATLFTSVRPSALIRE
IPEATAPDSAAPGDTTGHDAATLLRRLEGLPREDRERELVDLVRSQAAAVLGHATTDQVG
LDRAFRDLGFDSLTAVDLRNRLKAATGERLSATVVFDHPTPAELAAHLHDRCFPDADGRP
QASVPAVTAVAALHDEPVAIVGMACRLPGGVTTPEELWQLLRDGGDAITGFPENRGWDLD
GLYDPDPATPGKTYARDGGFLHDAAEFDAGFFGISPREALAMDPQQRLLLETSWEAIEHA
GIDPTVLKGTRTGTFIGANPSDYRAAMGQAPVGYEGHLVTGGHNSVVSGRIAYTFGLEGP
AVTVDTACSSSLTALHLAAQAVKQGECDMALAGGVAIMSTPEGFIGFSRQRGLSHDGRCR
TFSSDAEGIGLSEGVGVILLERLSDAHRNGHPVLAVIRGSATNQDGASNGLSAPNGPSQQ
RVIRQALANAGLTTAEVDAVEAHGTGTTLGDPIEAQALLATYGQDRTDGHPLYLGSLKSN
IGHPQAAAGIAGVVKTVLALQHGVLPRTLHVEEPSPEVDWASGAVELLVREREWPRTGRP
RRAAVSGFGISGTNAHVVLEQAPVSSGGVVPVPGVEPSEAVGADGAVGGVVPWVVSARSE
VALADQVGRLASFVDGRPGVGVLDVGASLLGRAGLDHRAVFAGRDRESLLSAVVTGPGAA
SAVGVVGVGDGRLGFLFAGQGSQRVGMGVELAAAFPVFGGVWREVWSLLGLSPDEVAVER
TGWAQPALFAFEVALFRLVESWGVRPEVVAGHSVGEVAAAHVAGVLSLGDAVRLVEARGR
LMEGLPEGGVMVAVGASEAEVVGAIAAHPRGEWVSVAAVNGPSSVVVSGVRGVVEEVVGG
LWGVVFGCGGWVCRMRFIRC
>G0PUE1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MITVSDEKKAVEYLKWVTADLKKSRQRVDELESAKHEPIAIVGLAARFPGGVTSADELWD
LVANGRDAITEFPSDRGWDVAGTYDPDPGRPGKTYTKHGGFIGSAPRFDAEFFRINQREA
LAMDPQQRLLLEVAYEAVENARIDPASLKGRQVGVFAGLAGQSYLHRAHFTSEELAGYVI
TGMVGSIASGRIAYSLGLEGPAVTIDTACSSSLVATHSAVQSLRNDECEFALAGGSTVIG
SIESWVEFSRQGNLSADGRCRTFDAGAGGTSWSEGVGMVVLERLSDARRKGHTIHAVIRG
SAVNSDGASNGLTAPNGPAQERVIQQALADARLTTSDVDLVEAHGTATTLGDPIEAQALL
ATYGQNRPADRPIWLGSLKSNIGHTQAAAGVGGIIKTVMALRHGVMPRTLHVQEPTPHVD
WTAGNARLLTEARPWPEVDRPRRAAVSAFGLSGTNAHLVLEQAPDGFAPELPASGVPEGG
LADSGSVPLPVSAKSAEALEEQTARLVEHLGRRPDLRPADVGFSLATTRTQFPHRAVLLG
GTVAARGVAGMGGLALMFTGQGAQRFGMGRELYAAQPVFAAALDAAIEAVDGALGDRVPV
SLRTVFFAPEGTPEAGLLDRTLYTQTSLFCLETALFRLFEHWGVTPDHLVGHSIGELAAA
HVAGVFGLGDAARLVAARARLMNELPRGGTMIAVEADEDEVTALLPADGSVSIAAVNGPA
SVVVSGDHDATTEVASTIAARGRRTKALVVSHAFHSHRMDPMLDDFRAVARTLSYQPPSI
PIVSTLTGKLADAETISTPEYWVKQVRRAVRFHHAVTHLDELGTTTFIELGPDGVLTAQA
RQSPAGHAFAPALRSGNGEVTTVLTALATAYVNGHPADWAAVFGDGARPVDLPTYAFQRK
RFWLDPGSAMTDVAGAGVHAAEHPLLGATVHTEDDSVMFTARLTRTTLPWLAEFTVAGRT
VLPSSALLELAIHTGDEVDCNQLRQLTVHSQVVLPEHAPVQLQVCAGAAESDSSRTVVIR
SRPDGSEGAWTLHATGVLTSTALAAAPPADAEWPPAGAVAVTAEEVDSALDGLGLGYGPA
FLGVEGLWRDGAALYATVRLPESVPGDGFAIHPALLVSALRPYVAATSGLPSEWSGVHLH
AVGASALNVRLTPDGDGGTSLLATDAAGQPVLTVDSLRTRPFLLQGEDTEVREALLGVEW
APVNLPSPVEGRWAFVEDELPYDAETLLFEPVREGDGPVAVTHDAAGRTLDLLQRWLLLG
EDVKLVVLTRGAVHTDAVDPAATAVWGLVRSAQNEYPGRIVLVDTDTPARDSLPAVLAAA
ASDNEPQIAVRDGRAFVPRLVRTPASTVRAPRLGGEGTVLITGGTGALGKVVARHLVTAR
GVKHLLLVSRSGRAPELVAELSALGAEVRVEACDTTDRDALEALLGGLEHPLKAVVHTAG
ITEDGMIATMTAEQLHAVLRPKVDAAWHLHELTKDLDLDAFVLFSSMAATVGGPGQGNYA
AANCFLDGLAQHRAGLGLPAVSIEWGLWEEASAVSAHLTPVILSRMAREGMRQIPTPLGT
AILDTALSLGRSLVIGQPFDATLAREHAAHANVPALMRKVLRTQNRRTAAARQSSGGALL
DRLAGLPADEQREVVLRVVLDTTSTVLGHDTTGSVTAGQNFGDLGFDSLTAVDLRGGLLA
ETGVQLPVSLVFDHPTPDDLTDRLLSELLGAPGGGRVVDFAAEVRLADDIRAADTVHRTD
DPRQVLLTGATGFIGSFVLRDLLRTTSATVHCLVRAADEEAAYAKIRAASAYYRTGIELD
RVRVVLGDLGAPGLGLDAATADRLAREADVVFHIGAHVNWLYPYAKLKAANVTATEEILR
IAAKHRTVPVHYISSTGVYANLPEEGVRLSEDAPIGPPEQLLSGYRQSKWVCEEIIGIAR
ERGVPVSSYRVDVVTGDQVNGACQTQDFVWLSIRGIVEAQAVPNSLESHFHPTPADYVSG
AMLQLAWRLTGTGDTYNLSNPERLTFGEIIDALRARGHRIDDLDLTAWTRKVRSDRSNAM
QPLLDQFVGLVGLPGGTYPSIDCSKADAALADTSVVCPPVRSDLLETYLDFFTEVGYLPA
P
>G0Q9T8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ACT-1|TrEMBL
MSHAFHSVLMEPMLGEFRGVLESLEFGVPSVDFVSSVGGGGDVGSVEYWVRHARAEVRFA
DVVGELGGRGLTALVEVGPDATLTGMAGQVLADPGGPVLVALCRKGRDEAVSVVEGVGRV
WACGVAVDWASLCGGGRRVDLPTYAFQRDHYWLPKAHGSSDAEGLGLSNTGHPLLSAALP
MADGGSVVLTGRVGRTSHAWVADHQVGGVVLLPGTAFVELAVRAGDEVGCGRVEELTLQA
PLILPERGGVRLQVVVEGPDATGGRPVAVHSRPDDGDTWTLHATGLLTEPGALPAGDAET
WPPADAERIELDGFYEGLADRGYHYGNAFRGLTSAWRHGSDILAEVALPEDNDAASYGIH
PALLDASLHPALLEAAGSDDENVRLPFSFNGVELHASGAAAARVRIAWAGTDTVALTLLD
AAGHTVAVVDGLVSRPVKGELGAAAGASSLFHLDWKRAADAATTAPVRGGGRWAVLQHPD
ADVLSALKDAADSVDTCADLDELIALMDAGTAAPDTVVLAMPSTTGAVDDGLTAAVHRRT
AEALATAQRWLADERFAGSRLVCVTRGAVSTAGDAVTDLPGAALWGLVRSAQAEHPARFA
LVDIDDSVASWDVLAEAAASGQDQLALRAGTRLTPVLAAAGAAPEDAPDVRLDAGTVLVT
GGTGTLGGLVARHLVTRHGVRRLLLTSRRGRDADGVTELVADLTAAGATQVTVAACDTAD
PAALADVLAGFGDDDPLSGVVHAAGVTDDGIVGGLTSEQLARVLRPKVDAAVNLHRLTRH
MNLAAFVLFSSFSGVLGSAGQANYASANAFLDALAQHRRTLGLPGVSLAWGLWEQSSGIT
ARLDRGDLARGSRAGVRALTTEQALALFDRGLTADRALLVPVALDQRALAARAVTEPVPQ
IFRDLVRVPARRMAAAHPGTGGQDGPTLAERLATVPVEKRDALLLDVVRGHAATVLGHGS
PGTVAAETGFLDQGFDSLTAVELRNRLAVESGLRLPATVIFDYPTPTALARYLGYELAVV
DGTDPRAAEEGRVRQALSAIPLNRLREAGVLETLVRLAGLESADAAVGTPDHDGDPEGTA
EGDGAAGIDDMDLDDLLRLAENDQ
>A0A139XLM6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii ARI|TrEMBL
IRGIFHAAGVTADASLANQTREAIEQVYLPKVTGAWNLHEVCESMGLDKNLDMFVMFSSV
AALLGNFGQANYSAANACLDALAEYRRARGLCAQSIQWGPWIEQGMAADLKALAEKAGLR
GISNELGIRVLVEAVRNSKTVVTFLAQSFIWKRFVQRFDVVPPFFSNIEFETASPGAFRV
LYSSMTPDELHTYVSNVVLDTARQVLGTSELPALDSPLQELGIDSLGAVELRNSLSQRLG
VKLSATTLFDYPTIRAIIDYIVNQVSGEASAAKATSGALVSAGLAAGRNSPIAVVGYSCR
LPQGSETPDKLWEMLRRAQDCVVEVPLTRFDVDMFYDSDIDAKGKMYVRKACFMDDADMF
DNSFFNISAAEVTYMDPQQRVMLEVAYDAFYSAAYSREHLIGKNYGVWIGCCNSDWHFLE
QQSNPDKSSSYSGPGGSGCLVSNRLSYVFGLKGPSMTIDTACSSSLVAADCGAQAMRFGY
CDGALIGGVNLMLSPQLFLAFCKARMLSPDCRCATFDEKANGYVRGEGAGAIMLRHLADA
QREGKRILGIVRGTAVNHDGRSASLTAPNGPAQQDVIRSALQIGGVDPLDVALVESHGTG
TALGDPIEMGAIKAVYGAGRSADSPLVVGALKSYIGHLEGSSGIAGILKVLLCLRHHEVP
PNLHFDTPNPHMDLSDFHVVLPKKQMKLQPAQKSSTILGSVSSFGFGGANAHVVFEEYPE
PTMATDVGGERRSTEAAESAGKKRLAFLFTGQGSQYPNMCKQLYEEEPVFRSHMDACFTV
LEGKLDVKLRDVIYPTAENDVEMLNLLNQTGYSQPAIFCVEYALAQLMISKGFSPSVVMG
HSLGEYAAAAIAGVMDWKDALLLVHERASIMQHIDPNDGVMYACRASEQDAQAAVEKALG
EKAVAVTVSAINGPRSIVLAGTQPDVLAVLKAMDMQSRAKQLTVSHAFHCPLVGEAAALL
LPKVESVKLSNPNEGITFISTVTGKAVGAGELTKPEYWAMHITKPVQFLQGMRAAVTSGE
AGIFIEIGPRPTLVNMGQQCVPRNDYTWVAPVDPKDSNRNSFPQALEKITSNMVCTYTWK
RHAFPWTVVVHPFVDKFVPDQDETKATSQKLLTPAVGELLHDHVVNGTAMMPGVGFLEAM
AAGGFMMVDGKLPSTVVALRDCEFERPMLIPKIDPSTGEFTQAAKLMITVNNKDITLKSI
MDGEEEEIFHSRCTFSLCPATSLPTEPADLLTSLQGRITTPVPITTLYETLQSVGLQYGA
RFQSIRECYAAASDEVLAKLRPKLPLHSFERNFRIHPVLLDGALQTAAVLFAEMGHKRPL
VPVGVKRALLARVPAGSEVWSHVVVKSKDLRSATMDVTLFSTKGTILGQLVDVAVRAFDA
VAGAQIPKGLLWEVSWVPKAKAPVEDGVDTVENEASETITPTAKLAVKPTGKVEGLARQP
AVNGQPKWLLLKTPSSMLEGLQKALQGTPSAFVKELDEKHPNNAISSKIHNSEWDAIIYL
GALSAAASSTTCVADALLLANTLGNTAAEKPLPNVLFVTQGQHFIRECGDVPTTAVPTQT
GLYGFCRSAQLELENIIGRPVYLGTLDFAAKDPTLDDPAAFVSALQRVLAEADPTGAAGT
CEPHTVIRGGKEMVPRLVKSSIECRGAVELHMSDRGALSMLKLRPMPKSARVPPPRDCVE
IRVRAVGLNFRDVLNVMGLYPGDPGPPGADCAGTVVAVGEGVEHLRVGDAVFGIAQGALK
TFVTTSAHLVRPLPGRLTFEQAAALPVVASTVEYALHDVAKVKKGDKVLIHAVTGGVGLA
AVQFCKRVGAEIYGTCSGGKKEEFARSVGVKYITSSRDPKKFAEDMCEFLGNGKHKIDVV
LNCLIENYIPETLKFLAPNGRFVELGKRGIWTREQMGTVRPDVLYETVAIDTMMEEDPVW
FGGMLDRIRNLVDGSMLQPLPLHTFEMTDSSEGGVAAFRFLQRAQHIGKVVIRLSSALEV
KNFTTNSRQETENEDSGERHTLSPATAVGKPLSQSVADQMHKTYIITGGTGGLGLVVAQW
LIEEGAHNIVLLSRRGEPPSSVKAGDPVWKYLCGEEQPNCISVATLKCDVSQKDDLLRVF
KEIESRGLPPVAGIFHAAGVTADAALASQTADSVDQVYLPKAIGAWNLHDACEALGLNKS
LEVFMMFSSVAALLGNFGQANYSAANACLDALAMYRQSLGLCGQSIQWGPWIEQGMAAQL
TQHLEKVGMRGITNELGLRVLGDVMMHPTVAVVGAQSLQWRKFLRRYAFEMPSFFSLVPM
AGAGSSEASVNLATITKEDLCELISSLAQAVSGAAEKPAVDTPLMDLGLDSLGAVEFRNS
VADKVGVKLPQNLMFENPSISSISDYILDKAAGKHGESGVTGANGGSGEGSDIPALDTPL
DQWLMSVLEPAERFALYIDSFASEYGTLQKMAAEEDIITALEDLGVEDGGDFERLHVAWD
DLCNQINTAKRMAAKDIRPSSTAVSVSDHPKPRMPHPMEDVDTLLASLDFDVSTLRPATA
PDKVKNVLLTGVTGFVGRVQLASLMQLKQRPDLRVYCLVRARNADHALSRIREATKEAKC
WQETFVSRIVPVTGDFTQPLLGLSSEEFQELARKIDIVYHTGGDVNLLSNYGRLRATNVL
SVKAIIDLCTTYKVKPLHFASTLGQFPAFFAMFTGHFSGESIREDSTPDVSQMENFYPPS
RQGYPWSKWAAERVLEGARKRGLPVAIYRLPNTYVAYKTGYTNKTDYATALMIASIQEGV
FPIGAATAPLTPVDTICDMLVEASFLEKPKHWVYHLFDPRLVTRADLEQWSQELGISYVG
VKVDEFLEAIKKRGPESPVFKFVPLMQHWRRFWFDPEERTESFPISNEHIFEDLPHMRWP
SLREVFKNSLLYSVRMGFFPKNSKSIILDPQVALNEARRICGLQLMGREGEDFFLHPWRV
LQESARRECDLLFGGQLAVYRTVRHYFMNVMYLADAQAKCPEIEKQEIQAPLIIVGLNRT
GTTFLQNLMSTDPSNRSLRYCEMIAPYGPDGNYRPKGLPNTEESWKKDPRIPFAQEILDS
QLGLSEEWMAIHTQRAELPEEDFVIFEHCGRCYSICTEFSVPSYREWLASDNYKETRKAY
SFHKRFLQHLQWQRPAKRWLLKMPFHLFTLEALFETYPDAKIIFMHRDPKETMGSWASLV
KHAQQSLMDNVDPSALGREELRAMSTMINRALAFRRSHPELGPRFLDVQYQDLVNNPIGV
VKSIYKHFGIPLTLAAQTGIASFCNENRKHRDKLTKHMYSLKDVDLTDGMVQEAFKEYYD
SGLCKYLSSAR
>A0A0N1H1Z6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OV450|TrEMBL
MSNSDQKLLDALRASMKETARLRTQNRNLSAAAREPIAIVAMSCRFPGGVDSPESLWQLV
DEGRDGVSGFPVNRGWDVEGLYDPEGERPNTTYVNKGGFLHDADRFDPALFSISPNEALI
MDPQQRLLLEASWEVFERAGIDPHTLKGSKTGVYSGMMYHDYAYNSATGSIASGRVSYAF
GFEGPSVTLDTACSSSLVAMHLAAQALRAGECTLALAGGVAVMSTPEVFVEFSRQRGLAK
DGRCKSFAAATDGTGWSEGVGVLLLERLSDARRNGHQVLAVIRGSAVNQDGASNGLTAPN
GPSQRRVIRAALENAGLTTADVDVVEAHGTGTTLGDPIEAQALLATYGQDRDADKPLWLG
SLKSNLGHTQAAAGVAGVIKMVQAIHHGVLPKTLHIDEPTPHVDWTAGNVKLLTESVEWP
AGGRPRRAGVSSFGLSGTNAHVIVEEAPAPAETTTAEEDTAPEETARGFVPGLVPWALTG
RTVQALRAQAARLVTHLETLDEGDLAVTGRALATRRARLNERAVVLGETREEPLAGPT
>B2J683|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MINSVNINGFNNEIAIISLAGRFPEAKYLDSFWQNLRDGVESISRLTDEELINSGVSLDL
LNNPNYVKANAVLSDIELFDANFFAYSAKEAELIDPQQRLFLELAWEAIEKAGYDPHTYN
GLIGVYAGVGMNRYLVNNLYPHHQLLETVDPLQLTISNDKDFLPTRVAYKLNLTGTAVNV
QTACSTSLVAVHLACQSLLNCECDMALAGGVTLSIPQKIGYLHQEGMILSPDGHCRAFDA
KAQGTIASSGAGIVVLKRLKDAIADRDHIHAIIKGSAINNDGAMKVGFTAPSVSGQAAVI
GEAQAIAGVDAETISYIEAHGTATPLGDPIEIAALTQAFNQSTDKKGFCAIGSLKTNLGH
LDTAAGVAGLIKTVLALQHQMLPPSLHFETPNPKIDFANSPFYVNTTLTEWKTNNTPRRA
GVSSFGIGGTNAHVILEEAPVFEQGSREGSAVLGVPPRSNCRRAGEQGRNYQLLVLSAKT
ASALEQATANLITHLKEHPELNLSDVAYTLNSGRRGFNYRRMLICQDLEDAVKTLSSLEA
QQVFSNYTEITERSVVFMFPGQGSQYVNMAREIYETETVFKEQIDYCSEVLKPLLGLDLR
HILYPSEEKIHEASKQLQQTAVAQPAIFVIEYALAKLWQSYGVEPQAAIGHSIGEYVAAT
LAEVFSLEDVLSLVAARGQMMQQLPTGAMLSIPLPADKIKSQLGQELSVAAINQPSQCVV
SGSTAAVDTLQNQLAAQGIECRQLHTSHAFHSQMMEPILKAFAERVKKVTLNPPKLPYIS
NLTGTWITVTQATNPDYYAQHLRSTVLFAQGVEKLLATPEQVLLEVGPGHTLTTLVKRHP
DKAAAQTVLTSVRHPQEKQSDNHVLFTTLGQLWLAGVNIDWFGFYSHQEHYRLPLPTYPF
ERQRYWIDPPQKTAWGQLQALPTPSQLWTSLVQGGQNQANTKNAELNELTYQENRQWLNR
LCTAYINSAFRQLGAFSNVEEKYSLENLLVQCHISPRYQQLFSRWLQILVEQGQLQEQEG
LFTGLRPCSQDYINEHLEEVRARFATSSLVDLDLVQRCGENLAAIVVEQEPLEIFNELVY
QKGNNGSHSESPLNTYYNSILHSSLEQVVKLLPLPQASASAAFSIKSRLEQNNQKSEISL
QKKPDIFQPEKLSALHSRPDLPNSYVAPRNEIEQKIADIWEELLGIKQVGIHDNFFKLGG
DSLIAVQVLSRIRNIFSIRLSVANLFESPTIAEIAPKLEKQIDPDTNFSAGEREEITI
>K9XMH6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Gloeocapsa sp. PCC 7428|TrEMBL
MTTNGLEVAVIGMAGRFPDAESVDQFWQNLKNGVESIHPLTDEFLRQQGVPQTDLQHPQY
VKAEAVLPNIDLFDADFFGFNPREAEILDPQQRLFLECAWEALETAGYDPQRYHGAVAVY
AGSAINSYSFNLYTNPQSRLLDNYQLFLASDKDFLTTRVSYKLNLTGPSVDIQTACSTSL
VAVHIACQSLLSGECDMALAGGVAISQPKGYLYQEGGIYSPDGHCRAFDAKAQGTVAGSG
LGIVVLKRLEDAVADGDSIYALIKGSAINNDGASKVSYTAPSIDAQASVIRAALTMAEVE
PETISYIEAHGTGTALGDPIEIAALTQVFGANSQHCKIGSVKTNIGHLDTAAGIASFIKT
VLVLKHKQIPPSLHFEQFNSQIPPDRPFEVNTTLSEWHAHSFPRRAGVSSFGIGGTNAHI
ILEEAPEEGQGSQCVAEVSSVVATGVGIAGGLNHRRAEVQGKYQLLVVSAKTHSALETAT
ANLVNHLRQHPDVNLADVAYTLQVGRQAFAYRRFCVCSSLEEASEVSAYAEATVPQHGTP
AITFMFPGQGSQYVGMGRELYAEAVFRSHIDRCCELLAPHLGINLWDLVQSSTNLNDTAY
AQPALFMIEYALAQSLMNWGIRPEAMIGHSIGEYVAATLAEVFSLEDALKLVAIRGRLMQ
QQPTGSMLSVFLSAKQIQPWLSAEIALAASNAPNLCVVSGNPTAIAQLEQRLSDAGISYG
RLHTSHAFHSPMMSPVQAEFIEVMKSVKLNPPKIPYISNVTGTWITNEQATDLAYWGKHL
RETVQFDAGITTLTQQPRILLEVGPGNTLSTLAATHRPISTLRHPQANDSDIAFLLNAIG
KLWLSGVGINWDNFWHERRKRIALPTYPFERQRYWIEPQPDSVINDRNWLYVPFWQRDRT
IASVDLNTVEKSCWLIFIDAEGLGNSIAQQLASAGHDVITVVAGAQFGELDYRCFSINPE
NRQDYTTLVEDLHSRELNFDRVVHFWSLDRTDYCSFYSLLFLTQAIASSTTVEITLVTNG
VYDILGEEELHPTTATVLGLAKVINQEYSQIACRHIDVMLPRSQLIGVLTELITPPTDFA
VAYRGQHRWRQKYQLVEETNAIQLRSFGHYLIVGDVTQGLGRVFAEYLAKMPAKLAIVSD
DIPTSWVDTLTAMGAEYFPVTVDITDESQMQRAIAQVEAQFGEIHGVFYSTPMSNQYSAA
PIAELGQNECEYNFRTKVAGLCVLQKVLQDKNLDFCLLQSSLSAIIGGFGLGAYAAANTF
IDAFAQHQSRRTSYPWLSVNWDAYDEAESIESSRALTSSEVWQATQQILAIDAVQVVVSK
SPLAAKIEQSISVRERESQVENNNHNRPNLSSQYIAPRNEIEQAVAAIWQELLGIEIGIN
DNFFELGGHSLLAIQVIARLRTTFQVELPIRSLLFEAPTVAKIAEVIAGQQPQQMADLLA
EIQSLSPAEIEQQLNARE
>A0A0F0L7U1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Microbacterium oxydans|TrEMBL
MTTDQTILLFPGQGAYAPGCIDEAAVIDPQTYEAVRAVGVELLSVDIEELRHDPRPLSAL
VQDASKAIQLSIFLAAVVAGNRALGASSPQSLIGHSFGEIAAWTVGGAFTPADGARIVAH
RVLALDAHAARDGAMAVFKAVRGQVAALLDAVGSDSLVIAGTNSTDQIVVSGPVNLLSKA
ESLAAVLDIATARIASPYAFHNPQLWGARAAFQDAVAAVPQLRLMRSAVAPAKAKRWRLT
KPAAMRSRDRFTSTRATSPASSPTRRMSGSSFHTLSIPPSMHLRSQDCSRRPQIPSSSLP
SNKWWTFSVRRNVRYGTGVYGR
>F1T736|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
MENINLKEYLSQLSSGENSALNVYNYLSNCNYSIGLNLNYFQESWVPSPSIQNRKPKGVL
AFAEEVQHYKYPCNVYVRNSSAYKFSENKEALIDFKNPQHYKHLFEDLNKRNIEIDTIIV
HSSNGNSDTILKAYNIVKAVAAAKQNSSLLCLWVYENRELNSCFHKALKGFAKTAFEEMQ
NVILRTVCIEEANQAFSGIDKIIESEASDFSKEFEVTYNKNGRMVKRFNFLKKFEDNEQI
SFSAKDAYIVSGGHGVIGREIVKSLFENGAGKVIITGRSEVADSQLKEWFGQNASKIQYY
RADIAVSKEVKTVHNSIKNNGYDIRGIINCSGVFNNSFIINKKENDIFDVLSPKINGTIA
LHEEFINENLDFFITFSSIAGVLGKIGQADYAYANCFLDNFAAYREGLRTDGVCKGKTIC
INWPYWSEGGMAIDDYEIDVLYEQLGAVPLTNKFGVEAFNKLLNAKSGSYTVLYGVQKKL
REVLEKAQITEFTDNAVSADYSTPDLKSKTNEWLIKIFKDTFGISDFDTGTGFGELGIDS
VGFNRVMLRIEKQLGPVKKTLLYETKNINEIADYLLETMSDKLEKILCVSMPAVPPVKVN
AYVIEKPTERIVEKVQEPCDDIAVIGISGRFPKASNCEELWEVLKNGVDCVGEIPKERWD
VDYYYSSEIKNLPEGKSYCKWGGFLADADKFDPQFFNMSPIEAAMTDPQERLMLEVAWEV
FEDAGYTHERLKKFGDENGNALVGTFMSTASNTYNLIGIEQWGKGNYVVPNSLPWSLSNR
ISYFMKFSAPSYTVDAACAGGLVAIHQAISSLKNNECKMALVGGANMYLHPYKYVSLSQV
KMLSKTGKCYAFSDKADGFVPGESVACVLLKPLKAAKRDNDRIYGVIKASEINHDADSNG
YMAPNPKAQELLISNAIKKAGISAKEISYIEAHGTGTPIGDPIEVNALSKAFRRTTSENQ
FCSLGSIKTNIGHSEGAAGIVGLIKVLLQMKHKALVPSLYSDKLSPVIDFDNSPFYVQRT
LEKWNKPLITDQGVQKECLRTAGVSSFGAGGANGHILVQEYKEDKKSIYNEDTEQVYILP
ISAKTQAQLGIYVNLMYQYISNNKSNLKLSAVAYTLQRCRNEMEYRAAFLTKTLDGFIKL
MSDYLNHKDSRNFFSGIVKKNRGKEISRTAIEDMETARSMAEAWVQGNKISWYETRRLVP
DLVDLPTYPFAQKSCWVKTINKTIPVRPEVKAAAEDDLEVILQELASDEGDIARIIEKIE
TIDKTNIK
>A0A011N152|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Candidatus Accumulibacter sp. SK-12|TrEMBL
MRGRIAITGHSFRMPGTTAETYWQDLLDGRNLVGTVDPQRWNLATFLHPRKDHPGTSYTF
AAGSIGDVITFDAAFFGISPREAALMDPQQRLLLEMSWEALENSGTPPSRLRGSRCGVFI
GIASADYSFRMVDDLAVADSTMATGNTASIAANRISYVFDLRGPSMAIDTACSSSLVALH
QACRAIASGEVSQALAGGISLHLHPYGFIGFAKASMLSPRGRCQVFDEAADGYVRSEGGG
VFFLKDLDQALADGDPILAVIAGSAVNTDGRKSGLTVPSAEVQAALLEEVYADAGIDPAT
IDYLEAHGTGTAVGDPIETLAIGNALGKRRPAGRPLPIGSVKSNLGHLETASGVAGLLKA
LHCLEHRVVPATIGVNQVNPRILASDWNIDLVTSNRSLPKTGKLTIGINSFGFGGSNAHL
IIESPPRRRSRPQPATVAAAVPPLLLSARSEEALKAAAGILAAFLADQPSAAYYDVAYSA
AFRRDWLEQRLIVEAPTLPEIRNALLDFAADRGGNAALNSGRVVVAARGPAFIYSGNGCQ
WSAMGRRLLAEEPLFRQAVLEVDALFRQHADFSLLAELAGENGDERYERTEIAQPALFAL
QVGITRLLQVHGVTPMVVAGHSVGEVAAAWAAGALSLADAVAVIHQRSLLQGTTRGDGQM
TAVALDKAAAASLLDELGLAGQLTIAGVNSVRGLTIAGAQSALTILEEALSLRHVGWKRL
DLDYAFHSPAMDRLKPGIRQALAGIEPRASVLPFCSTVSGSQLAGEELGADYWWRNIREP
VLFAQAVDSLLDQGITVFVEIGAHPILRTYLHDCLKARSIDGQVIATGTRDDDGALRIRS
AAHAVAIAGAAVDWRTHFPRPGRFVRLPGYPWQRERHWHPVTSESLGLIHRQKIHPLLGH
PLAQHELTWENQLDTQLNPVLADHVVGEATVLPGSAYVEMALTASLAWQPSAIVEIEDLE
IRSPLLLADDRSAVVRLSIDPRDGSLTIRSREQMSPADWVVNAAARIVREAQETLLREVL
PDLPQRPPDFDADSHALLTRAVGIAYGPAFQCVEHGWIDGNSAFAALRVPPQVETEVACN
HLHPALLDSTFQLMFQLLRQAIDRHEAIAFIPTRFGRVIFRSGTDTPRFARATLLRRSAR
SLQGEFALFCAAGRLIAIVKDARFRGVRLSRGGRDRLRFLALQAIPKPHAGQPAGPLALR
FDRVHSTLANVTQRAALKGTHRRYTEEVDPLLDSLCSRFTRRALQPIAGEDGTLSAAAIL
SCQSANPDGTPFLTDLIRLAGDDGSLTATGDGWTLVPDQREESTAEDIWNSLVADYPDYF
QIIHSVGRIGLHLPALVAGSASLCQICPQESSLATLLQQVVGGRARMKLGQALGALVTEA
LAALPPGQRLGVVEISDGAPAFAMDICFALDFTRSDYCFASPSPTALGEARVRLGEFFPT
IRTSLIGDAAGSEADQESPTGSCTMAIVMLDFATTEQALRALRHARRCLAAGASLLVLGQ
HPSRWIDFVFGARREGWSQSASGRWLSSQRPRSFWQQQLADLGCRCADPCEFSPDTLSGP
YLLLAEVDEVNPQPEVTARGSVRSWIVLADPVGYSARLADELARKLQERKDLVIQASATD
TEELAGLLQATTTSYGELDGLVMLTGLVPASPALSAEEALDRQVERCALAARIMQACERS
ATRTTCWLITANAGAALLPAAAASASDASRPDPSDDAALCGFVRTMLNEAEPGSVRLIDL
ALPMPAQTAAGLLDREFEQPDGELEIILTAAGQRYVPRLRDEPRPDARTPRLLESPTVSL
GFPFAGQLRNLRWETHPRVAPAPDEVEVEVLASGLNFRDVMYALGLLSDEAIENGFAGPT
LGFEFAGVISRVGGNCTGFSPGDEVVGFAPSSFGNRVLTQRSAVAHFPPGLSAEAAATIP
STFFTVYYALHHLARLQAGERVLIHGAAGGVGIAAIQIARWLGAEIYATAGSDEKRDFLR
LLGVSHIFDSRSLSFADQILEQSGGEGVDVVLNSLAGEAINRNFRVLRPFGRFLELGKRD
FYENSRIGLRPFRNNVSYFGIDADQLMLLHPELTRRLFAELMELFSAGILHPLPYRNFEA
EDVVEAFRYMQQARQIGKIVITYHHGIKRLQPPRPGARRRLQLAADASYLVTGGLSGFGL
RAAEWLASRGARHLILISRGGPDSASAEAAIRRLEEQGVRVHAAACDVTSRDALATLLAA
TGDELPPLKGVLHAATVIDDALVRNLDETQIRRSLAAKVLGARHLHELTRPCALDLFVLF
SSATAAFGNPGQAAYVAANTWLEELAAHRRAQGLCATAVGWGPIADCGFLVRNEKMREAL
ENRLGGAALTSELALDVLEEMLLSDRSGLAALEFAWQALSRVLPSAGSPKFGELASPCGG
GDDDQPQDIRRLLAELSDDELLVVIGDMLRSEIGEILRIAPEKIDASRSLFDMGLDSLMG
VELAVALDARFGIRLPVLALSQSPTINRLAERLLQQLRETEEGARGEATPDELRAQAAQI
ARQQGVAVSAEEIARFAADLDAAQQGEHRPTSDRHGT
>A0A7K0D3C7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nocardia macrotermitis|TrEMBL
MTETGARVAFIFSGYGALWEGMGVALLHQDATFRAAIREVSGHFDENLDWSVEEQLKSAR
TGDYRNLTVGGPAIFAVQYGLIRALAERGITPSVTVGVSFGEYAAATASGILALPETCRL
VAASALALKAANGIGGTATAAISEDRAHDIVAASHGDIQIAVVMSEGGVLLAGTDSALHE
LGTQLAREGLYYRVLEEFPYPYHSPLMAGVCTAFRQQMDSVRTAPATVPMISTVTGDYVE
GTDLDIDYWTKHFVTTTLLQQAAARAARTETVFLEVGPRPHLQTPLRTHRGPDGERLLVL
PTLTRHKPGTAALDEAAERIRDQ
>A0A3N6G962|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI96-15|TrEMBL
MQELPTGGAMVAVRATEAEVVPRLTEGLSLAAVNGPDSVVIAGVQEEVQSLAARFAEEGR
KTQPLPVSHAFHSALMEPMLAEFRRVAESLAYAEPRVPVVSDVTGALAEPGQLTDPEYWV
RHVRETVRFADGVRALAEAGADAFLEIGPDGTLTGMAARVLDTAADGTGSVSVPALRRDR
SEERALLTALARLHTAGVPVDWTAWFTGTGARRTELPTYAFQRELYWPEPAAGPHTPTAQ
DPADAAFWAAVEREDLESLSATLDLDDTVLSSVLPALSTWRRGLSERTLLDGWRYRVTWQ
PVPLRNTADDGAGGPWLVLTPAAHDDAWTEALAATFGEHAVHLAVPADEDGTAVLLSTAA
DGTAYAGVLSLLAGTATDGTARPDTLLRLLAAAGIDAPLWCVTRDAVSVGRSDSAADPDR
AALWGLGRTLALDEPERWGGLVDVDHVADARAVERLRAVLTAARTDGQAEDQVALRASGA
FGRRLSRAAASAPDVTWHPAGTVLVTGRAEGFGGHVARWLAAHGAAGVLLAGPAGPEDAT
TTALRAEMEALGATLTVVRHPDPADAAPLTEALAAQSDDRPLTAVFHTGDTGEEKPGVAG
ARAAYEALTTAVGDRDLDAFVVFGSISAVWGVGGQGAGAAAGVCLDALVQRHRARGTNAV
SVSWGAWQGAGPDGLAAHLRANGLPAMEPARALDALAPAIGEAAADPAAPASVTVADVAW
DRFAPAFTRSRAGLLLTGVPEAREALSTTGGDGADAGTASALRERLRQSDPSERLRTLLD
TVLTEIASVLGHADAAAVPAENAFNDLGFDSLTAVDLRNRLTTVTGLTLPATLVFDYPTP
AALAGHLLTQLLGEDTGPGTGVPVARAAADADDPVVIVGMSCRYPGDVRSPEDLWELVGA
GTDAIGGFPTDRGWDLEKLLHGDEDGRGRSVTREGGFLYDVADFDPAFFGISPREALVID
PQQRIVLQAAWEALERAGIDPAVLRGGDTGVFVGGGSGDYRPAIGQSGHVETAQSASLLS
GRLSYTLGLEGPSVSVDTACSSSLTALHLAAQAIRSGECSLALAGGVTVMSTPVGFVEFG
EMGALSPDGRCKPFSDAADGTAWSEGVGMLVVERLSEARRRGHEVLAVLRGSAINQDGAS
NGLTAPNGPSQQRVIRKALAAAGLTAREVDAVEAHGTGTTLGDPIEAQALLATYGQDRPE
GQPLLLGSVKSNIGHSQAASGVAGVIKMVLAMRHGTLPRTLHAEKPSRHVAWDPGAVHLL
TEAADWPETGRPRRAGVSSFGASGTNAHVILEQAPTGPAAPARDAEPATHATDAARLLPL
PLSAVTADSLTEQAARLRDRLTAGTAQPPATADLALSLGTTRSAFEHRAVLAVAGRDDLL
DALTALAEDRAHPAVLRGRAAPGGRTAFLFPGQGSQRPGAGRALYARFPVFATALDEVLA
HFDQELERPLRDVMFADEGTPEAALLDRTGWTQPALFALGVALHRLVESWGVRPDLLAGH
SVGEIAAAHVAGVLSLADACRVVAARARLMEALPAGGAMLAVRATEDEIAPYLTDQVSLA
AVNGPESVVVSGDEKAVTALAEAFAARGGKTRRLRVSHAFHSLHMDAMLQDFERVARSVS
YAPPKLPLVSNLTGDAVTDAQVCDPGYWVRHVREAVRFGDGVHTLAGRGATRYLELGPDG
ILCGLAQETLDALADENRPAPTAVPALRTGRDEEQALITAVARLHAAGQGIDWRALLDGT
GARRVDLPTYPFRRLRFWPDEAPAAGTGTTADAGDAAFWAAVQDEQFDSLAGELGVDGDA
LLRVLPALRDWRRKHGDQTTVDGWRQRIAWRPLNRATAGAPAGTWLAVVPADHAGHPWTT
AVLAALGTGAQVLEVSGEDRAGLTAAIRERLDATGPFTGVVSLLAVAGEPGDGTGALPGG
VPVGVALTATLVQALGDARTDAPLWCLTRGAAAVSPAETVAAPLQAAVHGLGRVAALEHP
QRWGGTVDLPLAVDARTAERLAAVLADPEGEDQLAVRPGAVFGRRLAAVRPGTPRDWKPT
GTVLITGGTGALGARTARRLAGAGARRLVLLSRSGPDAPGAGELAADLRALGAEPVITAC
DTADRKALAAVLAAIPEDAPLTGVIHTAGVLDDGVVDGLTPERFATVFRAKVASALLLDE
LTRAHDLEVFALFSSASAAVGNPGQGTYAAANAVLDALAEQRRAEGLPATSVAYGAWGGE
GMADGVRAAALARRTGIRPLDPDLAVLALRQVVTGSDPVAVVADVDPDRFVRAFTTVRPS
SLLAEMPAYAALKKAASAGGEAADSGPSLRDRLARLPESRRTQTVLTLVRERAAEVLGLT
GTDQVGPDRAFRDLGFDSLGAVELRNQLGAASGLTLSATLVFDHPTPAALAAHILGQLLP
AGTPGAPARDGAGEEERAVRAALAQVPMDRLRESGLLDQLLDLAGQNPAGTGPDQEAEPS
GAGDAYDASIDAMDVDGLVQAALNGNPDEERD
>A0A5P9PRP9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Amycolatopsis sp. YIM 10|TrEMBL
MSCRFPGADGPHQLWRLLAAGRHAITDRPPGRGAPDRTVAPPWGGFLDAVDEFDAEFFGI
SAREAAAADPQQRLVLELGWEALENAGIVPDSVRGGRLGVFVGAFADDYAHLAHRNGSTA
ATQHTYPGIERAVIANRLSHYLDVHGPSVSIDSGQSSSLVAVHMACQSLLSGESDLVVAG
GVQLNLLPESMDIADRWGPLSPDGRCYTFDARANGYVPGEGGGLVVLKRLENALADGDTV
HCVILGSAVNHGGNGRALTQPNEAAQRDVLRRAHERARISATELQYVELHGTGTPAGDPV
EAAALGAVVGSGRPRTQPLPVGSVKTNVGHLGAAAGIAGLIKVAMAIRHRELPASLNFER
ANPDIALDELNLRVQQSLGPWEAPDRRLIAGVSSFGMGGTNCHLVISDAPIASDRKPEAG
ETDSGQPPAVLPFVLSARGLGALCGQAARVRSFVVERPDVPLVDLAFSLVSGRAVFGDRA
VVVASGREDLLDRLAVLAAGETAAGCVAGGGRLAVVFTGQGSQRVGMGRELYRRFPVFAA
AFDEVCGLLDPLVRAAVFGDDDGRLNLTEFAQPALFAVEVALFRLFESWGVVPDFVAGHS
VGEISAAYVAGVLSLGDACRLVTARGRLMQGLAPGGVMVAVAAGEDVVAPLVAEQGTEVS
IAAVNSPTSVVVSGVEAAVERVVRRLAELGCRSKRLVVSHAFHSPLMEPMLDDFRAVVAG
LEFRSPQIAMVNGAVADPGYWVRHVRDTVRFADMVEQLHGRGVARFVELGPDAVLTGLVR
ECLDGRDVTAVPSLRHGHGEVESVLSGLGGLFAAGVAVDWPELFTGTGARRTELPTYAFH
RQRYWLDMTIDDEKTSVASPSPVSELRGHRLTELARTHITATLGGGVLSENALGQTFREL
GFDSFMSAELRDRLSHALKVSLPSSVIFDYPTPAVLIEHLRSAVLGRDVDVRAQVVSTAD
ADDPVVIVGMACRYPGGVGSPEDLWSLVVEGGEGITGFPESRGWDVGGLYHADPDHPGTT
YARGGGFLHDAGEFDAGFFGISPREATAMDPQQRLLLEVAWEAFERAGIDADSLRGTQTG
VVVGATPHGYGPVRADAGGYLLTGTTPGVLSGRIAYQFGFEGPAMTVDTACSSSLVALHL
AAQALRSGECSLALAGGVTVMATPMILTEFARQRGLSPDGRCRSFGAGADGTGWSEGVGL
LVLERLSDARRNGHEVLAVLAGSAVNQDGASNGLTAPNGPSQQRVIRQALANAGLTAADV
DVVEGHGTGTRLGDPIEAQALLATYGREHADGTPLWLGSVKSNIGHAQAAAGVAGVIKMV
MAMRHRLLPKTLFAEDPSTEVDWSSGGVALLSQAREWPDADRPRRAGVSSFGISGTNAHL
VLQEPSNEPGRRVADEPRLGRQDTAHPSTPATTLASPVLPFVLSARGLGALCGQAARVRS
FVVERPDVPLVDLAFSLVSGRAVFGDRAVVVASGREDLLDRLAVLAAGETAAGCVAGGGR
LAVVFTGQGSQRVGMGRELYRRFPVFAAAFDEVCGLLDPLVRAAVFGDDDGRLNLTEFAQ
PALFAVEVALFRLFESWGVVPDFVAGHSVGEISAAYVAGVLSLGDACRLVTARGRLMQGL
APGGVMVAVAAGEDVVAPLVAEQGTEVSIAAVNSPTSVVVSGVEAAVERVVRRLAELGCR
SKRLVVSHAFHSPLMEPMLDDFRAVVAGLEFRSPEIAMVNGAVADPGYWVRHVRDTVRFA
DMVEQLHGRGVARFVELGPDAVLTGLVRECLDGRDVTAVPSLRHGHGEVESVLSGLGGLF
AAGVAVDWPELFTGTGARRTELPTYAFQRQHYWLDTSSLPDTDLAAVGLKPVDHPFLRAE
LPVDDAGALVLTGRLSVDQQPWLADHVVSGTPILPGTGFLALALHAARRTGADLVEELVV
HAPLVVPEHGDIQLQLVVDAPDDTGRRALRVLSRGGDTAGNDTWTRHADGTVAPPAEVAP
AGSASATGWNGEADPGARPIAITTAYAELARRGYDYGPAFRGLRTIRRGDDVVFADIVLD
ESQGYGDPVFDLHPILLDTAIQAALVGLFETADETLVPFAWSGVIVHTPAPSVLRARVRR
TGADSVAMVLTSHEGNPVASIDSLVLRPAPDASPTDHGEAALFRLSWLPKEVGALPSTDN
WAMAGEDPHNLGARVTGEGRPLDRYADLTALRAAVAAGAPAPSTVLTVTPTGGVHHMLRL
VQDWLADETMADARLVVVTTGAVDTGDNGRVDLDNAPVWGLLRAAQSEHPGRIVLVDVTS
GGEGAQRLAAAVATGEPQLALSAAGVRVPRLTRLNVDSGSTHATEKSVPEHGTVLLTGAF
GRLGRLLARHLATEHGVTSMLLVSRSGPVMPEARALVAELTALGLEVRAEACDVADRAEL
AKLLRGLPADRPLMAVVHTAGVLDDGVFTALSPQRLDAVMGPKAVAARNLHELTVDMPLS
AFVLYSSVSGLVGAAGQANYAAANTYLDALAHHRARLGLPATSLAWGMWDQGGGMAAALS
AGDLNRMARSGVATLSATEGLALFDAAVRRSEPLLVPLRLDIASAADGENVHPLLRELIA
PRRVPGPRPNGEDVTAQPARLLESVRAETGRVLGYHGRDSIGIDRTFKEAGLDSLTAVEL
RNRLNAITGLRLSPTAVFDYPTPRALVDHLLGQFTTSEETPETTGSPTSDADDPVVIVGM
ACRYPGGVGSPEDLWSLVVEGGEGITGFPESRGWDVGGLYHADPDHPGTTYARGGGFLHD
AGEFDAGFFGISPREATAMDPQQRLLLEVAWEAFERAGIDADSLRGTRTGVFSGVMYHDY
APALDQVPDQLSGAVLTGSAGSVLSGRVAYQFGLEGPAVSVDTACSSSLVALHLAAQALR
SGECSLALAGGVTVMSTPMTFVDFGHQRALSADGRCRAFGAGADGTGWAEGVGLVVLERL
SDARRQGHEVLAVLKGSSVNSDGASNGLTAPSGPSQQRVIRQALANAALTAADVDAVEGH
GTGTRLGDPIEAQALLATYGQAHTAESPLWLGSLKSNIGHTQAAAGIGGVIKMVMAMRHG
ILPRTLHAEQPSPLIDWSQGAVALLDRNQDWPGTGRPRRAGVSSFGISGTNAHVILEQAP
EQPAARQSEAVTRLGVSAFPVSGRGSAALAAQARRLRAALADSPDTDVAGFGAALANGGS
THSHRSVILAENRDELLAGLDAIAAGQAESSALVVAGTGEAGHDGPVFVFPGQGGQWVGM
GIELWEVSPTFAELMRTCDEALAPHVDWDGFSLRDVLAGAPGAPSLDRDDVVQPAVFAVG
VALSGLWASLGVRPSAVVGHSQGEFAAAVAAGALSLTEGARVVSLRSRVLRRLAAHGGMG
WVNRSADEVRERLADHPRLGVAAVNGPLSTVVSGATAELDRFLAVFGAEGARVRRVPINY
ASHSAVVESIRAELADTLGVVECSDGDIPFYSTVTGSLLRGRELDAGYWYRNLREMVRFE
DVVDQLLDSGHRSFHEVGAHPVLVNSIQELAEAKGTPVTTVGSLRRGHGGAREFLRNAAE
AFVGGVDVRWSRLFPSGQRPVRLPTYAFQHTHYWIEPRPNRSTRGTDVDTRFWNMVDEGD
LEGLTTALAISDDDGRSSLGTVLPALSSWRERSRQQETLAGWQYRVAWRPTEGSDGPLTG
RWLVVVPADIAEPEWLEQAVAALTVRGAQVSRVAVPRETEVEALCHQLVTALDGQPAGSV
VSLLGLDTAGDTVSVPGGLRGNLALVGAVSTLGLSTPVWCVTQDAVAVRPGDSVTQPRQA
ALWGFARHAGLEQPVPWGGVVDLPREVGHEDLAALAGALGDGESELAVRGGTVFCRRLTR
ITAGAPRTPRTPQPIERSALVTGGTGALGAEVARRLVARGTRHLVLASRRGPAAPGAAEL
TAELAEQGVSVSVVACDVAERAQLAELLDNWPAEHPLTTVVHTAGVLDDGIIDRLTPERF
ERVFRPKVAAAWHLHELTKDRDLADFVLFSSFVGTVGLAGQANYAAANSSLDALAAHRRA
LGLAGTSIAWGLWQGPGIADRDGVEQQLAARGLRAMDPRRAIQAMDQVIDRDETAAVVVD
VDWSSFATELAGTRSVSLLAELLPAQEADPGQSADGVADTDVRARLAGLPATERAYSLTE
LVRTTVAGVLGYPDTGSVESGRSFQEIGFDSLTALRLRNRLGAATGLQLPATLVFDHPTP
AAVAELVHTELFGEDTGTHESETADDAGLKQIIDRIPLASLRRAGLVDALLRLADTAPRV
EPADSAAPSTAIDSMDLADLIRAAYGRTDAGDQPEGPTS
>A0A5P9PXB0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Amycolatopsis sp. YIM 10|TrEMBL
MQQDEQQDKVVEYLRRVTVDLRRARERVQELERKHTEPIAIVGMACRYPGDVRSPEQLWE
LLAEGRDVIGEFPGDRGWDLDTLFRSGASLATEGGFVHDTADFDAGFFGISPREALGMDP
QQRLLLETSWEALERAGIDPESLRGSQTGVFTGTNGQDYANLLAGEATTGVIASVISGRV
SYTFGFEGPAVSVDTACSSSLVALHLAVQALRSGECSLALAGGVAVMSTPGAFTEFTKQG
ALAADGRSKAFSDRADGMGWSEGAGQLVLERLSDAQRNGRNILAVIRGTAVNQDGASNGL
TAPNGPSQQRVIRAALANAGLNPSDVDAVEAHGTGTALGDPIEAHALMAAYGQDREHPLK
LGSIKSNLGHAQAAAGVAGVIKMVLAMRHGALPKTLHAERPSSHIDWSSGAVELLTEQSA
WPRPERRAGVSSFGVSGTNAHIILEQAPEPVVEEEPVREAPVTGVVPWVLSARTEAALTA
QAARIRSAEGSIEDIGFSLATTRAALDHRAVALDRDVLDAFAGGEATAGVVTGVANSVGR
SAFVFPGQGSQWVGMGRELLDASPVFARRIEECAAALSSFVDWSLLDVLRGDGDLDRVDV
VQPTLWAVMVSLAELWRSVGVEPEAVIGHSQGEIAAAAVSGALSLEDAARVVALRSIAVA
ESLAGHGGMVSVALPAAEVELGRWGDRLSVAAINGPGATVVSGEVAALDELLATCEADGV
RARRITVDYASHSVQVEAIRERVLADLAPITPRSGDIPFYSTVTGEPIDTAGLDAEYWYT
NLRQTVEFERATRRLLDDGFDVFIEPSAHPVLTVGVEQTLEAAGVNGTVLGSLRRDDGGA
LRFLTSVAEAHVAGVAVDWPVFFGGAQRVDLPTYAFQRQRYWPAAANGAGDVRAAGLGSV
EHPLLGAAVELAEGENVFTSRLSLRSHPWLAEHLVHGKVLLPGTAFVELAVRAGDELGCD
RVDELTLAAPLVLPEQGAVQLQLRVGLPDDQGRRPITVHSRPEDAVDLPWTEHATGFLGT
GARPSTFDSVTWPPAGAEPLDVDGCYERFAENGFAYGPVFQGLRAAWQHGDEVFAEVALP
EGVSPDGFGLHPALLDAALHAAGLAELGVLSGGALPFAWEGVSLHAVGAATARVRLRAEG
NGLSVEVADAAGGPVASIDSLVLREVSTDQFGDPARDGLFRVDWVPAPAAVSEPILAVHE
TLESIEDVPEVVVLPLPELDSVRDLTAHALDLLQRWLADDRFADSRLALVTRSENAVWGL
VRSAQSENPGRFILIEAEDLALVPAAVATGEPQLAIRGGEILVPRVARVPAPASRFSWDP
YELVLITGGTGGLGGVIARHLVAEHGVRNLLLVSRTGRADVSDIDANVQVEACDVADREA
LAALLARHDVKAVIHAAGVLDDGVIGSLTAERLDNVLRPKLDAARNLHELTGDLSAFVVY
SAGAGVFGGAGQGNYAAANAALDALIRERHAAGLPGVSLVWGAWDRTIGLTGSVTDADLR
RLAQDGMPPLSAEQGVALFDAALATGEPVILPMNVDVPVLRGRSDVPPLLRGLVRTRARR
AAAGEETADTLARRLAGLGDAERVESLRETIRGLVAVVLGYAGAAAVDPSQTFQHLGFDS
LTAVELRNRLGAATGLRLPATMVFDYPTPTVLASYLAEELFGSRESHLHGTVTRRENLIH
GEDPIVIVGMSCRFPGGVNSPEELWDLVLNGTDAISGFPSDRGWDLDSLYHPDPDHPGTS
YARTGGFLHNAAEFDPDFFGMSPREALATDSQQRLLLETSWEAIERAGIDPVSLRGSQTG
VFAGVMYNDYGSLIEDDEGYQGTGAQLSVASGRLSYTFGFEGPAVTVDTACSSSLVALHL
AAQALRNGECSLALAGGVTVMSTPSTYVTFSRQRGLSEDGRCKAFADAADGAGFSEGVGL
LVLERLSDAQRNGHEVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLSTQDV
DAVEAHGTGTTLGDPIEAQALLATYGQDRERPLLLGSIKSNFGHTQAAAGVAGVIKMVMA
MRHGVLPETLHVDAPSSHVDWESGSVELLTSQVAWPEVGRMRRAGVSSFGVSGTNAHVIL
EQAATTTVEPTPVEHPVPLVVSARTEGALDDQLERIKALTNSPADIGYSLTLRSSFEQRA
VLLDGVEVARGTAVERPLAMLFSGQGSQRIGMGRELYSRFPVFAAALDEVLSHLDVREVM
WGGDQEALNQTGNAQPALFAIEVALYRLAESWGLKPDHLAGHSIGEVAAAHVAGVLSLED
ACTLISARARLMQALPTGGAMVAIQATEDEVQLVDGVSIAAINGPNSVVIAGEEAAVLEV
AAGFTKTSRLKVSHAFHSPLMEPMLEDFRSAIEHLTFHEPRIPISTTGDVTTVDYWVRHV
RDTVRFADNVAAIGDAHFLELGPGGVLAAMVAENALAVPILRKDQPEETSALTALARLHV
SGVPVDWRPFYDGAHRVDLPTYAFQHQRFWPTADHPLLGASVELGENEFVFTSRLSRWTH
SWLADHRVNGQILLPGTAFVELALRAADEVGCDRLDELTLAAPLVLPEQGAVQLQVRVTG
QAVTIRSRVEDGSPWLEHATGVLATTAERSTFDATVWPPAGAELFDVDGCYERFAELGID
YGPVFQGLRAAWRGGDDLFAEVSLPEGVEVGEFGLHPALLDACLHVAAFADGDTRVPFSW
QGVSLHATGATSVRVRLSASGEVAVADPSGQLVATIGALATRPLERTAAVRSDALFGLDW
LPVTASARSDLETVVFPVDTSGDVVTATHTATARVLRELREWLSDERSADARLVVVTGSD
PAGAAVGGLVRSAQAEHPGRFVLVEADDTELLPQAIAVDEPHVAIRNGEILVPRLVRTVA
QEPITWSGQVLITGGTGGLGLEIARHLVAEHGVRDLLLVSRSGVADVSDIDANVQVEACD
VADREALAALLARHDVKAVIHTAGVLDDGMLDSLTPESLDKVLRPKVDGAWNLHELTGDL
DAFVVFSSVAGVFGTAGQGNYAAANSFLDALAAHRRAQGLPGVSLAWGAWADTGMMAGSD
AERMSRAGMRALSPEEGVELFDAALAGEPLVLPVHLDLAALRARGDVRPLLRGLIRTRSR
RSAVGAEAADSLVRRLTALGEDERREVLVDLVRGQVAAVLGHGTTSRVEPTRPFKDLGFD
SLTAIELRNRLGAASGLRLPATLIFDYPTTLALAGYLRDELLGADADMSVPLRSLPPVTD
DPIVIVGMACRFPGGVGSPEDLWRLAVDGTDAVSGFPAGRGWDLDSLYHPDPDHPGTSYT
RHGGFLHNAAEFDPAFFGMSPREALATDSQQRLLLETSWEAIERAGIDPVSLRGSQTGVF
AGVMYNDYGSLVEGDEGYEGTSTSPSVASGRVAYTLGLEGPAVTVDTACSSSLVAMHWAM
QALRSGECSLALAGGVTIMSTPSTFVSFSRQRGLSEDGRCKAYSDDADGVGWSEGVGLVV
LERLSDAQRNGHEVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGLSTQDVDA
VEGHGTGTTLGDPIEAQALLATYGQDRERPLLLGSIKSNLGHTQAAAGVAGVMKMVMAMR
HGVLPRTLHAEKPSSHVDWESGSVELLTSQVAWPEVGRMRRAGVSSFGVSGTNAHVILEQ
AAVTTVEPTPVEHPVPLVVSARTEAALDEQVERIRSLDASPLDIGYSLTLRSSFEQRAVL
LDGVEVARGVSAERPLAVLFSGQGSQRVGMGRELYSRFPVFAAALDEVLSHLDVREVMWG
GDQEALNQTGNAQPALFAIEVALYRLAESWGLKPDHLAGHSIGEVAAAHVAGVLSLEDAC
TLIEARARLMQALPTGGAMVAIQATEEEIPLAEGVSIAAINGPNSVVIAGEEAAVVEIAS
GFEKTSRLKVSHAFHSPLMEPMLEDFRSAIEHLTFHEPRIPISTTGDVTTVDYWVRHVRD
TVRFADNVAAIGDAHFLELGPGGVLAAMVAENALAVPILRKDQPEETSALTALARLHVNG
VPVDWRPFYDGAHRVDLPTYAFQRRRFWPTAVRTGDASGLGLTAVEHPLLGASVDLAERD
GALFTSRLSASAQPWLADHVVNGRIILPGAAFAELALRAGDELGHDRVDELTLAEPLVLE
QGAVQLQVSVDDAGAFAIYSRPSADLPWTRHATGTLSTGEFCADFDTTTWPPADAQPVEV
DYDRFAEQGFAYGPAFQGLQAVWRTDEAIYAEVTLPEDVAPDGFGIHPALLDASLHAVLA
AGDGTPGMPFSWTGLSLHATGAKTVRVRLVQDGDTLSIALADPAGDLVASVESLVTRPIS
AGRSTGVTDLFEVEWRAVTAPAPVPVVTLDGPLKSVVDVPASLVVAVEGDTDVVASTHAL
TTRVLAMVQEWLGDERFAGSRLVFLTKAGDLAGAAIGGLVRSAQAEHPGRFGLIEADSGE
LLPQALAVDEPRVAIRDGEILVPRLARTAAQEPITWSGQVLITGGTGGLGLEIARHLVAE
HGVRDLLLVSRGGVADVSDIDANVQVEACDVADREALAALLERHDVKAVIHAAGVLDDGV
IGSLTPERLDNVLRPKVDALWNLHELADVDAFVVFSSIAGVFGGAGQGNYAAANAFADAL
MTHRRHQGLPGVSMAWGAWETGMAGALSEADTRRLERSGMPPLPAEQGLHLFDAALAGGP
LVVPVRLDLPVLRTRDEIPPLLRGLIRTRTRRSVAGSETAVGLVRRLTGRTEAERLDLLL
DLVRTEVAGVLGHTDATEVDPGKQFSELGFDSLTAVELRNRLGTTTGLRLPATMVFDYPT
PTALASYLAEELFGGRESQVHGTEVRRESHIHGDDPIVIVGMSCRFPGGVRSPEDLWRLV
SEGADAITEFPGDRGWDLDSLYDPDPERPGTSYTREGGFLHDAAQFDPAFFGMSPREAMA
TDSQQRLLLEGSWEALERAGIDPASLKGSATGVFTGVMYSDYASLLNGDDFENYQATSTS
PSVASGRVAYTLGLEGPAVTVDTACSSSLVAMHWAMQALRNGECSLALAGGVTVMSTPNT
FIAFSRQRGLAEDGRCKAYSDDADGVGWSEGVGLLVLERMSDAKRNGHNILAVVKGSAVN
QDGASNGLTAPNGPSQQRVIRQALASAGLSTQDVDAVEGHGTGTTLGDPIEAQALLATYG
QDREQPLLLGSVKSNLGHTQAAAGVAGVIKMVLALRHGTLPRTLHAGTPSSHVDWDAGAV
ELLTEPTAWPEVERVRRAAVSSFGVSGTNAHVILEQAPEAQPGEPAEPVAGVVPWVLSAK
SAAALRAQADKLSTVDADPVDVGYSLVTTRTAFEHRAVILGDDHRALLRSLDEPAGGVVT
GVAGALGKAVFVFPGQGSQWLGMGQDLLATSPVFAERVAECAVALDPFVDWNLLDVLRGG
EDFDRVDVVQPVLWAVMVSLAELWRSAGVAPDAVVGHSQGEIAAAVVAGALSLEDAARVV
ALRSQAVAESLAGHGGMMSVAQPVDELRPRLKLWGQRISVAAVNGPGATVVAGEDAALDE
LKAACEADGIRARRISVDYASHTPQVETIRERVLADLAPITPRTGEIPFYSTVSGEPIDT
ARLDAGYWVTNLRQTVEFERATRKLLDDGYRVFVEPSAHPVLTVGVEQTLEAAGVAGIVL
GTLRRDDGDWLRFTISVAEAYVRGVPVDWTAFFPEGARQVDLPTYAFQHERFWPSATGHA
GDVRAAGLGAIEHPLLGAAVELAEGEDVLTSRLSLRSHPWLADHAVNGQALLPGTAFVEL
AVRAGDEVGCDRIEELTLAAPLVLTEQAVRLQVRVGAADDAGQRPITIHSRPEDAVDEPW
TEHATGVLAVGAFTAELDTAWPPAGAEPIDVDDCYQRFAELGFEYGPVFQGLRAAWRVGD
EIFAEAALPDGVPPDGFGLHPALLDASLHAPLLVGVTDGGGGGLPFSWEGVSLHATAASA
VRVRFTPTGEGFAIAVADPAGAPVASVRSLVTRVVAEPVAQREPLFRVDWVPATAQSTVD
DYEVYQVETTDDVVAGTHAATAEVLGVLQRRQRDSRLVIVTRGGLAAAAVGGLVRVAQAE
NPGRFGLIETDGDVPPEAFAVDEPHVRVQDGKILVPRLARTQPETEFSWSGRVLITGGTG
GLGLEIARHLVNEHGVRDLLLVSRRGEADVSDIDANVQVVACDVADREALAALLAEHEVK
SVIHTAGVLDDGVIGSLDADRLDTVLRPKVDAAWNLHELTGDLDAFVLFSSAAGVFGTAG
QGNYAAANAFLNALAEHRRAEGLPAVSLAWGAWDQTGMLADKDAGERLGRAGMPPMTVEQ
GLALFDDAMAATEPTLVPIRLDLPALRAQGEVRPLLRGLVRSRSRRTVAGAETAMTLVQR
LASLGDAERTTALADLVRGQVAVVLGYSGAAAVDPQLAFQSMGFDSLTAVQLRNRLTSAT
GLKLPATLVFDYPTPAVLAAYLRDELFESRESHIHGTVKRPPVTHHHPQRSSAQSLSESN
LHGDDPIVIVGMSCRFPGDVGSPEDLWRLVSEGADAITGFPSNRGWDLDALYNPDPEVSG
TSYTRLGGFLHDAGEFDPVFFGMSPREALATDAQQRLLLEGSWEALERAGIDPASLRGSQ
TGVFAGVMYSDYATILDAETSEGFQATGGSLSVASGRVSYTFGFEGPAVTVDTACSSSLV
TMHLAAQSLRQGECDLALAGGVTVMSTPSTFVELSRQRGLAVDGRCKAFSDSADGAGFSE
GVGLLVLERLSDAKRNGHTILAVMRGSAINQDGASNGLTAPNGPSQQRVIRQALASAGLS
TQDVDAVEAHGTGTTLGDPIEAQALLATYGQDRDRPLYVGSVKSNLGHTQAAAGVAGVIK
MVMALRHGLLPKTLHVDTPSSHVDWEAGSVEVLMRATDWPEVDRVRRAGVSSFGISGTNA
HVILEQAPKSDAPLLDLPAGPAPIEGQAPWVLSAKSAAALDVQLERVRAVDADPVDVGAS
LLTTRTVFDTRAVLLGDGVVRGSVVEGASAPVFVFPGQGAQWAGMALELLDSSPVFAEWM
AECDRVVGSLVGWSVIEKLREGNEVLERIEILQPLLFAVMVSLAQLWRSVGVEPAAVVGS
SQGEIPAAYIAGALSFEDAAKIVVLRSQLFADELVGNGAVASVALTEEQLRERLPEGLTI
AGVNGPKALTVAGSLDLLDEFVAGCVAEDIRARVVPSTVASHCAQVDPLRDAILDMFADV
TPREANIPFYSTVTGGLVESSELGPEYWFHNARQPVNFAGAVKTMLDDGFRVFIEPSAHP
VLTMAAQQTAESLDVPTVTVGSLRRDEGGADRFTTSLAEAYVAGVGVDWRLFFAGTRARR
VDLPTYAFQHKQFWPEPSAPVTTVDPVDAEFWELVDEGDFATELDLDTDTAARVVPALAG
WRSRRRAKSTVDSWRYDESWTPIKPSGELSGTWLVVVPEGGEPVDLGVETVTLEVGAVER
EELAERLRGFEVAGVVSLLGTTDAPRIGAVPAGLSRSLTLLQALADAGIDAPLWNVTRGA
VAVADSAEVTDPDQAALWGLGRAVALEQPRRWGGLVDVTGEIDGRLAAVLSGDEDQVAIR
AEGVYGRRLVHAAPAEQVRRWQPSGTVLITGGTGGLGGYVARWAVETGAEHLLLTSRRGL
EAPGAPELRDDLEAMGARVTVAACDAADREALAELLAEHPVTAVVHTAGVGVGDAPAETL
TLDQLDALMRSKLTAAWNLHELTGDLDAFVLFSSGAAMWGSGGQPGYAAGNTFLNALAQY
RRAHGLTATSIAWGAWAEAGMATHEDMAEHLLRRGLLSMEPELAINAMQRAIEEDRTLIT
VTNTDWERFAPSFTSQRPSRLLSEIPAARQALADDAPEEESALKQRLAGLSESERTRVLL
DLVRTEAAATLGFDAAEDLPAGKAFREVGFDSVTAVQLRNQLKAATGLALPAALVFDYPT
PRALTEHLLEELFGSGEVSRESHVHSTTGDDPIVIVGMACRYPGGVTTPEELWQLVDSGT
DAIAGFPADRGWALDAINSATREGGFLTDVAGFDAGFFGISPREAVAMDPQQRLVLETTW
EAIERAGIDPMSLRGSQTGVFMGTTGQDYPNLPGNNGDKDVYATTSSVASVISGRVSYTA
GLEGPAVTVDTACSSSLVSIHLASQALRQGECDLALAGGVAVMSTPSAFNAFSSQGGLAA
DGRCKSFAEAANGTGWSEGVGVVALERLSDARRNGHTVLAVVRGSAINQDGASNGLTAPN
GPSQQRVIRAALAAAGLSTSDVDVVEAHGTGTVLGDPIEAQAVLATYGQDRERPVLLGSI
KSNLGHPQSAGGVAGVIKMVMALRHRVLPKTLHVDAPSSNVEWGAGSVELLTERTEWPET
GRPRRAGVSSFGVSGTNAHLILEQAPEVEPVIEQADLEPAVVPWLVSGRSAEALGAQFAR
LEAFVADNPEISPLDIGYSTVVSRSDFEHRAVLVDGTTEIARGVAGERSVAVLFSGQGSQ
RIGMGRELYLRFPVFAAALDEVLEHLDVREVMWGEDQEALNQTGNAQPALFAIEVALYRL
IESWGIRADYLAGHSIGEIAAAHVAGVFTLDDACKLVEARARLMQALPADGAMVAIQATE
EEVTPLLTEDVSIAAINGPGSLVISGNAQVTADIAASFAERGRKSRRLPVSHAFHSPLMN
SMLADFRTVVTGLRFDAPRIPVVSNLSGEIATPGQLADPEYWVRHVRETVRFADGVRTLI
GERVDTFLELGPDGVLSAMAAETTPESVTVPVLRKDRGEELAAVSALAKLHVNGVELDWR
GIFTGTGARRVDLPTYAFQHERYWPEPVDAEVEAGDTVDAEFWAAVEREDLESLAGELGV
GEEPLDALLPALSSWRNRRRARSTVDSWRYRETWRALPGAASGALSGTWLVVVPTGYGDG
EWLTAVLGSNMLRVEVAGIGREEITARLPGDFEGGFAGVISLLALDADLGGVTATASLVQ
ALGDAGILAPVWAVTRGAVAVDESEQVSEPWQAGVWGLGRVAALELPRQWGGLVDLPEVI
DEQVARRFADVLSGQAGEDQVAVRARGLYGRRVVAAPAPGGIGDWEPTGTVLITGGTGAL
GAQVARDLARRGAQRLVLLSRRGPDAPGAVELWDELTGLGADVTIIACDVTDRESVAQVL
AGIPAEQPLTGVVHTAGVLDDGVLEGLTPERFATVYGAKVDAAIVLDELTRELDLTAFVL
FSSVAGTVGNPGQGNYAAANAVLDALAQRRRSLGHAASSIAWGAWAGAGMAVDSEWAHRE
DSPVMDPELAVAALRQVVAEGAASMVVADLRPALGWLLGMRPTPSLGELPGARRLLDEAE
AARRATETVANELHRRLLELPETEQVDAVLDVVRGRVASVLAYPSANAVGVDNAFRDLGF
DSLTAVELRNQLNEATGLALPASLVFDYPTPRGLAEFLVGELLGRESHLHGIDGHRESHL
HGTRDNAEPIAIVGMSCWFPGDVRSPEELWELLVAGSDGVTGFPADRGWDLEEVFGGDNP
SITRHGGFLPNPAEFDPAFFGISPREALAMDPQQRLLLEGSWEALERAGLDPAKLRGSQT
GVFVGTNGQDYATLIANTGQETGGHGATGLAASVISGRLSYTFGFEGPAVTVDTACSASL
VALHLAVQSLRQGECDLALAGGATVMSTPLVFSELSKQGALAADGRCKAFSDDADGTGWS
EGVGLIVVERLSDAKRKGHNILAVVKGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGL
STQDVDAVEAHGTGTALGDPIEAQALLATYGQEREHPLWLGSVKSNLGHTQAAAGVAGII
KMVMALRHGVLPKTLHADEPSSHVDWTSGAVSVLTETKPWPEVGRERRAGVSSFGISGTN
AHIILEQAPEEEPAALPIKGTRSPIDGVVPWVLSGKTEGAVDAQLDRIRALDADSIDIGA
SLLTSRTVFDTRAVLLGDGVVRGSVVEGASAPVFVFPGQGAQWAGMALELLDSSPVFAEW
MAECDRVVGSLVGWSVIEKLREGNEVLERIEILQPLLFAVMVSLAQLWRSVGVEPAAVVG
SSQGEIPAAYIAGALSFEDAAKIVVLRSQLFADELVGNGAVASVALTEEQLRERLPEGLT
IAGVNGPKALTVAGSLDLLDEFVAGCVAEDIRARVVPSTVASHCAQVDPLRDAILDMFAD
VTPREANIPFYSTVTGGLVESSELGPEYWFHNARQPVNFAGAVKTMLDDGFRVFIEPSAH
PVLTMAAQATAEDLEIPVVAVGSLRRDEGGPARFTTSLAEAYAAGVPVDWTVFFAGTGAR
RVDLPTYAFQRQRYWPEPAKRKAVATADPVDAAFWDLVEDGDFAEALALDSDTAALVVPA
LAGWRSRQRTQSTVDSWRYRESWTPITATTAITGTWLALVPAGYAGDAWVAEVLAVLGDD
AVLVEVGDTHRTALAKELAEVAHNEFAGVVSLAGIAEAPAVGNVPVGLAMTLLITQALGD
TGIEAPLWCVTRGAVSVGQADPVRNPEQAALWGMGRVAALELPRRWGGLVDLPAEFDDRT
AERLAGVLTGTGEDQVAVRSAGVFGRRLVHAAPVAERPAEPWRARGTVLITGGTGGLGGY
VARWAAASGAEHLVLTSRRGLDAPGAVELREELEASGTRVTIAACDVADRDALAALIGDI
PDLTAVVHAAGVGVGDAAIEALTMDQLDALLQAKMTAAWHLHELTEGLDLDAFVLFSSGA
ANWGSGGQPGYAAGNAFLDALALYRRGRGQVATALAWGAWAEAGMVHDNPSMWEHLTRRG
LLTMAPELAITAMRQALEDDQAALTVTNTDWTRFAPSFTANRPSPLLSELPEVVEALAEP
ETAESGDAGESEFKQRLTAMPDAERGRALLDLVRNEAAATLGYDNTDALPANQAFREVGF
DSVTGVELRNRLKAATGLSLAAALVFDHPTPAAIAKFLKAELFGDDEPAADDPDTRIRET
LASIPISRLRKAGLLDMVLRLAGEDGEPEAAPAADGGDVSLDDMDAESLLRLATDGTSQN
>D9UBU4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces pristinaespiralis|TrEMBL
MLRAAAGERRPGGDGPAGGSMGRTLPAEAGSAGRVLEPVAVIGYSARFPGAEDADTFWQR
LLAGDDLVTEVPAERWKIDEHYDPRPEAEGKSVSKWGAFVDGADRFDAAFFKMPPREAEL
TDPQARLFLQEAWRALEHAGQRTADLAGTRCGVHAGVMMNDYQDLIERTSEHARLAQVMQ
GNSNSLLAARIAYHLDLKGPAVTVDTACSSSLVALHQACQALWLGDADMMLVGGVTLYLT
ELPHVFMSRAGMLSPTGRCRPFDAAADGIVPGEGCAVVVLKPLSRALADADPVHAVIRAS
GLNQDGRTNGITAPSAASQARLIGDTLGRFGLDASGIDYVEAHGTGTPLGDPIEVTALNK
VFAPAARPVGSVPIGSVKGNVGHTSAAAGLAGLLKAIGVVRTGDIPPSLHCTPHTLNPAI
PFGEGPFTVATERRTLPAAPGGRPRRASVSSFGFSGTNAYVVVEQAPHRPAPTPADRPVT
VPLSGRRPTAPADRAAELARWLRSPAGADAALTDLAHTLACARDHHPHRVALLVADRAEL
LDSLDKLAAGEPDPRRIDPATDPAHHGDDPRHHDARRYVAGHTVDWSSTCPPAGHRRIPA
PGYAFAPDRHYAVPALPPAAPASDEPPLDERLLDELVLRTPGWQDSPLPDRQPPALPLLA
HDPVGDLAAALGAGSLDALPAVQDTAPDAVALVLRLTGDETAAFDAVREVLAAFRTQRIT
LLAVTADVLRADAARALVQSLRQENPRLTGRALLLADDGPAAAPLIRAELACPEPEFGHL
ADLRTPRRARRVLHPATLPQDGFTPRPDGVYLITGGTGGIGRDLAARLTAHPGTRVVVCG
RTPLADLDPAHRPAPGGPLRYVRADIAAPGGAAALVSDILTHEGTLTGVFHAAGVVRDAY
LLRKNSDDVAAVLAPKTTGTTALDEATAALRLDVFVLFSSVAAVSGNIGQSDYAYANGRL
DAFAEHRAALVAAGQRHGRTLSVQWPLWDVPGMTIPEPVRRVVEEHVGMVPLPAALGARA
LERLLSAKGPQVVSLFHGRADAWHRHLQNLHLLPTPTPTPTPAPVPAPAPAPVPAPAPAP
VPAPAPAPVSAPEPGAAPEPVAAPRAGAATPDGDLVGLVARTVAETLGHAAGTIGPRTSL
EELGLDSVMIRTLASKLSARIAPIGPDALFGVRDVHELAGHLARSLPAAPSTPTPVPTPT
PTPVPAPVPAVASTPAAGTGREPAREPAAAPAGQTAGEEAFAVVGLAGRYPGADGPDAFW
ENLLVGKDTVGDLPTDRWADSGGVRAKGHFLDRVDAFDAAFFGLSAHEAAFTDPQERLFL
EVAWEAMEDAGLTGTRLDALTAPDGEPRSVGVFAGITSADYPLLGAERWAAGERDMPSGH
YWSLPNRLSYLLDLRGPSQPVDTACSSSLVALHQAVEALRQGECEAALVGGVNLYLHPSR
FRMLARSGFLAEDGLCRSFGAGGAGFGPGEGAGAVVLKRLSRALADGDTVYALVRGTAVA
HGGRTNGFTAPSPRAQARVLREALRRSGTDPATVNVIEAHGTGTELGDPVELTALNDTYG
RGAAAGVPCSIGSVKSAVGHGESAAGITALTKVLLQLRHKTLAPTLHAEPVNPRLRLQDT
RFTLQHEAGPWPRLRDEDGRELPRRAGISSFGAGGVNAHVIVEEYEPPAPTPADDGAPQL
VLLSAPSGEHLTATVRRLAAHLTGPAAAMSLAAIARTLRTGRAAREHRLAVVATDTAELA
AALAQFTDGTPGTPGAGTVRTGTVARDRAVQAPETDELVATLWRAGSLEQLAELWVTGWE
IGPTTDPDGDTGTPGVVPLPPSAFLRTRRWLPGPDTAPAPAPTPAPAPDVTAAPPAAPTP
APALDVPAPVPQVAPTAPAPDTAPAPDAAPAPAGTGHVAVTSAVASAAVPGDPRLPALAA
LVGELAAGPGAEGPIDPARTLVELGVDSLGLMNLRFEITERFGHTLPLQLLSEFSVDELL
AHLSALHAPDQA
>A0A3G4VMB3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-16|TrEMBL
MANEETLRDYLKLATADLQQTRQRLREIEARNQDPIAIVGMGCRYPGGATSPEELWQLVV
DGVDAITGFPAERGWDMETVYHPDPEHPGTSYANQGGFVRDFARFDPSLFGISPREALAM
DPQQRLLLETSWEAFERAGIDPTSMRGKQVGVFVGTSNHDYLTALLSSSENVEGYLGTGN
AASVASGRLSYTFGLEGPAVTVDTACSSSLVALHLAVQALRNGECSLALAGGATLMSAPG
TFIDYSKQRGLATDGRCKAFSPDADGFSLAEGVGVLLVERLSDARRKGHHVLAVIRGTAV
NQDGASNGLTAPNGPSQQRVILQALSNARLTPDQVDAVEAHGTGTGLGDPIEAQAIIATY
GQDRPDGRPLWLGSLKTNIGHAQAAAGVAGVIKSVMAMRHGVLPKTLHLTEPTPHVDWSA
GEVSLLTEARPWPLHEGPRRIGVSSFGMSGTNAHIILEGAEEPAAGLATDPAAEPGTEPG
TGPAVLPVVLAGKTESALRAQASALHAHLTARPELRVEDVAAAQALTRAALDRRAAVVAQ
DRDELLAGLAALAEGSPSADVVEGAATEGKLAFLFTGQGSQRLGMGRELYESQPVFAAAL
DEVCDRFALSLELPLKDVLFGSDADVLDRTEYTQPALFAVEVALFRLVESWGLKPDFLSG
HSIGEIAAAHVAGVFSLDDACALVAARGRLMQALPSGGVMIAVQASEDEVLPLLTDRVSI
AAVNGPRSVVIAGDEDAAVAVAEAFGDRKSKRLTVSHAFHSPHMDGMLDEFRAVVAGLSF
AAPSIPLVSNLTGSLVTDEMGSAEFWVRHVRDAVRFLDGIRWLESRGVTAYLEIGPGGVL
SALGQDCQTATGPRAAAFLPALRAGRPEARSLTAAVAGAHVRGLSPDWATRFPGAGTRRA
ELPTYAFQRDLYWPRDPFTDLSEPVDGRELGLTDAKFWEVVDSEDLAALAATLGVEGDEP
LSGVLPALSAWHRRHRDRDTVGSWRYRVTWKPLTDTAPGPLAGHWLLAIPAGHADDPWAV
AAARTLAARGATVSSVTVDALADDRAALARRITETLAGTPETAAPAGVLSLLALDERPHP
EDPALPAGLAATLALVQALGDADVAAPLWAATRGAVSTGRSDRLAGLAQAPLWGLGRTAA
LELPDRWGGLVDLPPTPDERAAGRLADVLGGLGTEDHLAVRSTGVFVRRLTRAPQEQPPA
GEWTTSGTALVTGGTGALGRHVARWLARTGAEHLLLVSRRGPDADGAPELAAELRELGAR
VTLAACDVSDPDAVAALLADVPADAPLTTVVHAAGVLDDGVLEAMTPRRLADVIRPKSHA
ANVLHELTRELDLSAFVLFSSVAAAFGAAGQANYAAANASLDALAEQRRADGLPATVISW
GAWAEGGMATDELVAERLRLAGLPALAPELALSALHTALSLDETSSLVADIDWDRLAPGL
SAVRPCPLIADLPEAAHALAAAAAAPDTATEGADAFARQLAQAPAAERDALAVEFVRTQV
AVVLGYPGPGSVDAAIAFRDLGFDSLTAVEIRNLLASRTGLRLPATLIFDYPNSLSLAAF
LQEELLGTRPADPAGATGAAAATGSGSGTATDDDPIAIVAMSCRFPGGVNTPEELWQLLV
TGRDAISGFPADRGWDLDGLYDPESLRDNTTYVGEGGFLAGATEFDPGFFGISPREALAM
DPQQRLLLETSWEAFERAGIDPATVRGERIGVFTGTNGQDYLDVILAAPDGSEGFLGTGN
AASVVSGRVSYVLGLEGPAVTVDTACSSSLVALHWAIQALRQGECTMALAGGVTVMSTPA
SFIDFSRQRGLAADGRIKAFAAAADGTGWGEGLGMLLVERLSDARRHGHPVLALVRGSAV
NQDGASNGLTAPNGPSQQRVIRQALASAGLTTADVDAVEAHGTGTRLGDPIEAQALLATY
GQDRADGQPLLLGSIKSNLGHTQAAAGVAGVIKMVLAMRNGVLPPTLHVDEPTPHVDWTA
GDIALLTEPVEWPETGRPRRAGVSSFGISGTNAHTIIEQAPETAAPALPVPAPDTVTPDV
PPLPWILSGKSRDALRDQARRLHAHAVLHPELRPADLGLSLALGRSAFEHRAAVVAADRA
ALLAGLETLAEGGSAAGLVEGSPVAGKLAFLFTGQGSQRLGMGRELYESHPVFADAFDGV
CAHVDLELPLKEVLFGSDADVLDRTEYTQPALFAVEVALFRLVESWGLKPDFLSGHSIGE
IAAAHVAGVFSLDDACALVAARGRLMQALPSGGVMIAVQASEDEVLPLLTDRVSIAAVNG
PRSVVVAGDEDAALAVAAAFPDRKSKRLTVSHAFHSPHMDGMLDDFRQVVAGLTFEAPRI
PIVSNLTGALVSDEMGSAEFWVRHVREAVRFLDGIRALEAAGVTTYVELGPDGVLSALAQ
DCIEQDAVFAPALRKDRPEAEAVTTALARAHVNGVGVDWAVYFAGTDAQRVDLPTYAFQR
QRYWPALSGLYLGDVEAIGLDDTAHPLLSAGVALPESDGMVFAGRLALSTHPWLADHAIL
GSVLLPGTAFVELATRAGDQLGCDHVEELTLEAPLVLPERGGVRLRVWVGAADDSGRRPF
ALHSRAEGLAAEEPWTRHAAGVLAEDARPAAGFDLTAWPPAGATEVPLEGRYDALDAIGF
AYGPTFRGLRTAWQLDGAVYAEVALPDGAEDQAARFGLHPALLDAALHAIGLDGIGADDG
QGRLPFAWSGVSLYAGGASALRVRLTPAGAEGVRLEIADASGAPVAAVESLGLRPVTAGQ
LRAARTSYHESVFRQQWTELGGLGAPDTVAPARYALLGDSGARIAGDADHYADLAALAAA
VDAGAAVPDEVVIRLAPAPGPLSAPAVHDAAHAALALAQAWLADERFAAARLVVLTRGAV
AATADEDVTDLAAATVWGLLRSAQTENPGRIALVDTDTGQDGGHAALRAALGSDEERFAL
RAGAVLVPRLARVETGREDGARTPAFGPDGTVLITGATGALGGLVARHLATSYGVRRLLL
VGRRGADAPGAAELVRELAESGATAIWAACDVADRDALAALLAEVPADHPLSAVVHTAGV
LDDGIVSSLTPDRLSAVLRPKVDAAWNLHELTRGLDLTAFVLFSSTSGVFGGPGQGNYAA
ANSFLDALAQHRRAQGLPATALAWGLWSVAEGMAGALDAADVNRMRRAGLPPLTAADGLG
LFDTALSLDDAALALMRVDTETLRPQAAAGTLAPLLRGLVRGVARRSATATAGAAGGETE
LRARLAALSAAEQDRALLELVRTQVAAVLGHASPAAVESGRAFKELGFDSLTAVELRNRL
NAATALRLPATLIFDYPDPTVLARHLRTELIGDDPEPGTAAGDAPGATAPATAAAADDEP
IAIVAMSCRYPGDVRTPEDLWQLLTAGADGITRLPENRGWDTDALYHPDPEHPGTSYARE
GGFLHDAAEFDASFFGISPREALAMDPQQRLLLETTWEVFERAGIAPSSVRGSRTGVFAG
VMYHDYGARLHAVPDGVEGYLGTGSSSSIVSGRVAYTFGLEGPAVTVDTACSSSLVALHL
AAQALRGGECSLALAGGVTVMFTPGTFIEFSRQRGLAADGRCKSFAAAADGTGWGEGAGM
LLLERLSDARRNGHQVLAVLRGSAVNQDGASNGLTAPNGPSQQRVIRQALANARLSADQV
DAVEAHGTGTTLGDPIEAQALLATYGREHSDDRPLLLGSVKSNLGHTQAAAGVAGIIKMV
MAMRHGVLPKTLHVDEPTPHVDWTAGAVSLLTEQVAWPDTGRPRRAGVSSFGISGTNAHA
IIEQAPQPDPDPRPAAGPDADTDTHAGGEPEGAPAPVVPVVLSARDEDALRAQARRLLTR
VHTDEGLRTADLALSLATTRSALEQRAALVAADRTELLRGLDALARGEDTAAGLVRGSAR
DGRLAFLFTGQGSQRLGMGRELRDAYPAFAEALDHICVELDRHLELPLKEVLFGSDAALL
DRTRYAQPALFAVEVALFRLLETWGVRPDFLSGHSIGEISAAHVAGVLSLQDAAELVAAR
GRLMQELPAGGVMIALQASEDEVVALLTDRVSVAAVNGPQAVVVAGDEDAAVAVAEVFEA
LGRKTKRLTVSHAFHSPHMDAMLADFRKVAEGLVYGTPRIPVVSNLTGSIVSDEMGSADF
WVRHVREGVRFLDGVRALDAAGVTTYVELGPDGTLSALVQDCLTDTATAAAGPAADAAVR
VPVLRKGRPEAEALTTALALAHAHGVTVDWTAYFSGTGARRVDLPTYAFQRKRYWLDVGV
SVEDVLAAGLDTPGHPLLGATVPLPATDGLVLTGRLALSTHPWLTDHTVMDTVLLPGTAF
VELALRAGAEVGCDTVEELAIEAPLTLADQGAVQLQLAVDTADETGRRTLTLHSRPADAP
AGEPWTRHVTGVLAPAGPARAFDLAQWPPAGAEPVPTDGFYPAAAAAGLGYGPVFQGLRA
AWRGEGALFAEVALDEAYAAEADAYGVHPALLDAALQAIGLGVPGDTGTGSGSDTGSADG
ARLPFAWTGVRLYAAGATGLRVRITAGESGGLALDVADATGAPVASVDSLVLRPVSAAQL
GADRTAHHESLFGVEWAKLPLAAGAIPAGERWAVLGEDPAEFRIAGEPLERHRDLTALRG
ELAAGAPAPDVVVVPLSGTAPAGGRAAAARTAAHQALALVKEWLAEERLDDSRLVLLTSG
AVAAVPGEHLTDLAHAPAWGLVRSAQSENPGRFVLADTDGSEASLGALAAALAGDEPQLA
LRSGEAYAFRLRRIGRTAATDAVDAVDGIDTTGTVLVTGAGGTLGSLFARHLADAHGVRN
LLLLSRRGDTAPGAADLTRALEASGAAVTWAACDAADRDALAAVLAAVPADRPLTAVVHT
AGVLDDGIIDSLTPERLDTVLRPKVDAAWNLHELTEGHRLSAFVLFSSVAGCFGAAGQAN
YAAANAFLDALAQHRAARGLAASSLAWGLWATTDGMAGALDEADLTRMARAGVGALAPEE
GLALFDTSRTLDEAVLVPMRVEPAALRAQAADGTLPPLLRGLVRTPARRAAVDPARRAAS
RSAAEPADSLQERLAGLPAAERDQALHELVRTQVAAVLGHGTADDIDPGRGFLDLGFDSL
TAVDLRNRLTAAAGLRLPVTLIFDYPSPAALAAYIGEKLGRGDAARRPVHTELDKLESLL
SAIAPDDAERAGITTRLRDLLAKWNDTHSAQDSAAEERDIQAATADELFDLLDDELGLS
>A0A3G4VMB2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-16|TrEMBL
MTTPNEKVVEALRASLKETERLRRRNQELTDASREPIAIVGMSCRFPGGIGSPEDLWKLV
ESGGDAISGFPDDRGWDVESLYDPDPDHPGTTYARDGGFLYGAPEFDASFFGISPREALA
MDPQQRLLLETSWEAFERAGIDPATLRGSRAGVFVGASANAYGAGSGELPDGVEGHLLTG
TASSVVSGRLAYVFGLEGPAATVDTACSSSSVALHMAVQALRQGECSLALAAGVTVLAGP
DVFVEFSRQRGLSPDGRCKSFAEAADGTGWSEGVGVLLVERLSDARRNGHRILAVVRGSA
VNQDGASNGLTAPNGPAQQRVIRQALESARLTTADVDAVEAHGTGTTLGDPIEAQALLAT
YGQDRPADRPLWLGSLKSNLGHTQNTAGIAGIIKMVMAMRHGVLPKTLHVDRPTTHVDWT
AGGVALLTEQRAWPETGRPYRVGVSAFGVSGTNVHTIIEQAPEADRAPEADRPEGAAGPE
PKAVPWLLSAKGQDALRGQAERLLAHAGEHPGLSPVDVARSLAVGRTAFEDRAAVVAADR
EGLLAGLAALAAGDAAPGVVTGSPAGGKVAFLFTGQGSQRLGMGRELYETHPVFAAALDA
VCERLDLELPLKDVLFGTNTDVLDRTEYTQPALFAVEVALFRLLESWGVKPDFLAGHSIG
EIAAAHVAGVLSLEDACALVAARGRLMQALPGGGVMIAVQASEEEVLPLLTDRVSIAAVN
GPRSVVVAGDEDAATAVVAAFPDRKSKRLTVSHAFHSPHMDGMLDDFRQVVAGLSFEAPR
IPIVSNLTGALVSDEMGSADFWVRHVREGVRFLDGIRALETAGVTTYVELGPDGVLTALA
QDCVEQDAVFVPVLRKGRPETESLALALARAHTHGTRVDWHAYFSGTGARRVDDLPTYAF
QRQRYWIEPGTRAGDVSTAGLDEAAHPLLGATVALADSDGYVFTALLSSTTHPWLADHQV
MGSVLLPGTAFVDLAIWAGDQVGCDLVEELTLEAPLILPERGGVQLQMYVSAPDADGTGR
RAFGLSSRPKDSAPDELWTRHASGVLARGAVPARPDSAFEQWPPAGAEPLATDTLYADLA
EVGMGYGPAFRGLTAAWRHGDSVYAEVTLPEGTASAARDFGLHPALLDAALHTLGLGVLG
GTEGEGRLPFTWSGVRLHAGGADALRVHLAPRGADGVRLEIADTTGAPVASVDSLVLRAV
SAEQVQAARTAHHESVFRTEWTALPAAAAAADLSDPVREGRWAALGAAAPAALLPDAAAD
AAAITVHAGLAELAAAVEAGAPVPEAVFVGYGQADAIADADAGAPATPELSAEAVHRAAH
HALDLARTWLGEAPFTGDRFAATRLVVLTRGAVAADDTDTVTDPVHAAVHGLLRSAQAEH
PDRLLLIDTDGAEDSVRALPAALAAGEPQLAVRAGTVHAPRLTRVAREDADEPTPTDAAS
GSGQVYAPESTVLITGAGGLLGGLIAHRLVAEHGVRHLLLVGRRGGSTPEAQRLGAELAA
AGASVTWAACDVADRDALAAVLAAIPAEHPLGAVVHTAGVLDDGVITSLTPERLSAVLRP
KADAAVHLHELTRDLDLSAFLLFSSIGGVFGGAGQGNYAAANVFLDALARHRRSLGLPAT
SLAWALWADGAGMAGSLTDADVSRMTRGGLPPLTSAEGLDLFDLAHRLDEAAPVLMRVDL
AGLRTQAQAGTLSPLLRGLVRVPTRRHAGGAAAVAGGSGLRQRLAGLPAAEQDRMLLDLV
RGQVATALGYPGAAAVEPGRSFKELGFDSLTAVELRNLLGEATGRRLPATLVFDYPTATA
LAQYLRQELLGDLDADPGSGADRGGLPARRPAARAARAADDDPIAVVAMSCRFPGGVTSP
EELWQLIAEGRDGITAFPADRGWDLDTLYSDDPDREGTSYVREGGFLHEAADFDAAFFGI
SPREALAMDPQQRLLLETTWETFERAGIDPTGLRGSRTGVFIGSNAQDYLQLWLNDADGL
EGHLGTGNAASVVSGRISYSFGLEGPAVTLDTACSSSLVTLHLAAQALRRGECSMALAGA
VTIMSTPGAFTEFSRQRGLAENGRIKAFAAAADGTVWSEGVGLLLLERLSDARRNGHPVL
AVVRGTAVNQDGASNGLTAPNGPSQQRVIREALADAGLTAGDVDAVEAHGTGTRLGDPIE
AQALLATYGQDRPADRPLLLGSVKSNIGHTQAVAGAAGVIKMVMAMRHGVLPQTLHVDEP
TPYVDWSAGDIELLTEQRDWPETGRPRRAGISSFGYSGTNAHAVIEQAPRHTEAPAHEAP
AAPGLPGLPVLPWLVSGRTAAALRAQAERLLPTAADVSATAVGDRSALDLGHSLATQRAA
LEHRAVVIGAPSDGEALVARLAALAAGEQVPGLVRGTVSGGGLAFLFTGQGSQRLGMGRE
LYEAFPAFAAALDAVCERLDLELPLKDVLFGTDAELLDRTEYTQPALFAVEVALYRLVES
WGVRPDFVSGHSIGEIAAAHVAGVFSLEDACALVAARGRLMQALPEGGVMIAVQASEEEV
LPLLTDRVSIAAINGPRSVVVAGDEDAALAVAAAFPDRKSKRLTVSHAFHSPHMDGMLDD
FREVVAGLSFETPRIQIVSNLTGSVVSDEMGSAEFWVRHVREAVRFLDGVRVLEGAGVTS
FVELGPDGVLSALAQDCLAGAADVAFVPVLRAGRGEAETLVTAVAQAHVRGAEVDWSAFF
AGSGAGRMELPTYAFQRQRFWPETILSNGAVVAAPTVDAVDARFWDAVERGDLTSLASEL
AVDGDARFGELLPALSAWRRQGQEQSEVDGWRYRVSWKPLTDAATGVRLSGSWLVVVPAE
GVDDAAVVAALAVRGAEVRRVVVEAGVDRAGLFSGVGPVAGVVSLLALDEAAGVVATAGL
VQALGAAGVEAPLWCLTRGAVSVGRSDRLVSAVQAQAWGLGRVAALELPERWGGLVDLPE
VWDERAMARLVGVLAGSGEDQVAVRSSGVFGRRLVRATGGGAGSWTPSGTVLITGGTGAL
GGRVARWLAGAGVERLVLTSRRGLDAPGAAELVAELGVDVSVVACDAADRDALRALLEAE
AEGLTAIVHTAGVLDDGVLDALTPERFESVLRAKATSALNLHELTVELGIELSAFVLFSS
MSGTIGAAGQGNYAAANAYLDALAEQRRAAGLAATSIAWGPWAEGGMAADEALEARMRRG
GVPPMNADLAITALRQAVGSDDAALTVVDFDWAKFVPGFTSVRAGKLLGDLPEAEAVTRA
TENAGDRSERSGSSLAERLRSMSAGDREPFLLDLVRHQVAEVLGHSGAQDIEAGRAFREI
GFDSLTAVELRNRLGAATELRLPATLVYDYPTPAALAANLLSELLGAQVEVTGPVAAAVE
DDPIAIVAMSCRFPGGVRTPEDLWQLLASGSDAISDLPLDRGWDLDALYDADPSAQGTSY
ARQGGFIYDAADFDADFFGISPREALAMDPQQRLLLETSWEAFERAGIDPETLRGSQAGV
FVGTNGQDYLSVLMEEPEGLEGHLGTGNAASVVSGRLSYVFGLEGPAVTVDTACSSSLVA
LHWAIQALRSGECSIALAGGVTVMSTPGTFIEFSRQRGLAADGRIKAFAAAADGTGWGEG
VGMLLVERLSDAQRNGHPVLAVVRGSAVNQDGASNGLTAPNGPSQQRVIRAALASAGLSS
AEVDAVEAHGTGTTLGDPIEAQALLATYGQDRADGQPLLLGSVKSNIGHTQAAAGVAGVI
KMVLAMQHGVLPQSLHIDEPSPQVDWETGEIALLTEQRAWPETGRPRRAGISSFGFSGTN
AHTIIEQAPLPQAAGEATGPVEPHSLPLPLVISAKNDEGLRAQADSLHARLLADPELRPS
DVGRTLATGRSAFEERAAVVAVDREGLLAGLAALAAGESAAGVVKGSPAGGKVAFLFTGQ
GSQRLGTGRELYDAHPVFADALDAVCARFDLELPLKEVLFGDDADLLDRTEYTQPALFAV
EVALFRLVESWGLKPDFLSGHSIGEIAAAHLAGVFSLEDACTLVAARGRLMQALPSGGAM
IALQASEEEVLPLLTDRVSIAAVNGPRSVVVAGDEDAAVAVADAFPGRKSKQLTVSHAFH
SPHMDGMLEEFRQVVEGLSFETPRTPIVSNLTGALVTDEMGSAEFWVRHVRDAVRFLDGI
RALEAAGVTTYVELGPDGVLSALGQECLSDDGAVFVPVVRKGRPETETVMAALARSHVRG
IPLDWQAVYGTGVVRVDLPTYAFQRRRYWPEAALVRRGSLGAQSDIDGWRYRASWKPLTD
AATGVRLSGSWLVVVPSEGVDDTAVVDALTARGAEVRRVVVEAGVSGLFSDAGAVAGVVS
LLALDEAAGVVSTASLVQALGAAGVEAPLWCLTRGAVSVGRSDRLVSAVQAQTWGLGRVA
ALELPERWGGLVDLPEVWDERAMARLVGVLAGAGEDQVAVRSSGVFGRRLVRAADGGAGS
WTPSGTVLITGGTGALGGRVARWLAGAGVERLVLTSRRGLDAPGAAELVAELGVDVSVVA
CDAADRDALRTLLEAEAEGLTAVVHTAGVLDDGVLDALTPERFESVLRAKATSALNLHEL
TVDLGIELSAFVLFSSVTGTWGTAGQGNYAAANAYLDALAEQRRAAGLAATSIAWGPWAE
GGMAADGALDARMRRGGVPPMNADSAVEALHRALAVNDTVVTVVDVDWARFAPGFTAVRP
SSLLAELPEARNALAARAGREGGADTAADGRHSLAQRLAGLSAAERDRVLLDLVRKEVAA
VLGHAGAESVGAGRAFKELGFDSLTAVELRNRLGAVTELRLPATLIYDYPTSADLADHLR
GELLGDEAAVAALVPAARALDDGPIAIVAMSCRFPGGVRTPEDLWQLLATGGDAIGEFPA
DRGWDAESLFGPQAEQDASYAREGGFLYDVAQFDPGFFGISPREALAMDPQQRLLLETSW
EAFERAGIDPSSLRGTQAGVFVGTNGQDYLSLVLNSADGGDGFMSTGNSASVVSGRLSYV
FGLEGPAVTVDTACSASLVALHLAVQALRSGECSIALAGGVTVMSTPGAFVEFSRQGGLA
ADGRIKAFAAAADGTGWGEGVGMLLVERLSDAQRNGHPVLAVVRGSAVNQDGASNGLTAP
NGPSQQRVIRAALASAGLSAAEVDAVEAHGTGTRLGDPIEAQALLATYGQERPADQPLLL
GSIKSNIGHTQAAAGVAGVIKMVMAMQHGVLPQTLHVDGPTPHVDWSTGEVALLTERRDW
PETGRPRRAGVSSFGVSGTNAHTILEQAPAAPAAVEEDSPGTWPWILSGRTENALRDQAA
RLLAHLGAEEEPRPVDVGHSLATGRALLDHRAVIVAGEREEYREALSALVAGDSAAALTR
GVASTEQQTAFLFTGQGSQRLGMGRELHDAFPVFADALDAICAHMDAHLELPLKEALFDA
DADVLDRTEYTQPALFAVEVALFRLVESWGVRPDFLSGHSIGEIAAAHVAGVFSLEDACA
LVAARGRLMQALPAGGVMIAVQASEDEVLPLLTDRVSIAAVNGPEAVVVAGDEDAAVAVA
AAFPDRKSKRLTVSHAFHSPHMDGMLADFRKVAESLSYGSPRVPVVSNLTGALVTDEMGS
ADFWVRHVREAVRFLDGIRVLEAAGVTTYVELGPDGVLSALAQDCVTADATFVPLLRKGR
AEAETLVTALGRAHVHGVTVDWAALYSGTGARRVDLPTYAFQHERYWVDSFVTPEDAQSL
GVESAGHPLLGAAVELPDTGGFLFTGRLSRRTHPWLADHVVADSTVLPGAAFVELALRAG
DEAGCGQVRELTLEQPLVLPEDGAVQLRLTVGGADGDGRRPVQVHGRPETADGDGADGGT
WSRHATGFLTAPGETAAPANTGPWPPAGAEEMPVETVHDRLTAAGLHHGPALKTLTRVWV
RGEEVFAQARLSDELHASAGGYALHPALLDTAVQALAAATTPGDTAGREALVWRGVRLHA
AGADAVRLRITPDGADTVSVELADEQGAPVATVEALVTRELDAERFTVAPDGVHDALFRL
DWVRTAVPARHAATTFAVIGGATDAAAAALGGAGIPAAAYEDLAALDAAITAGRQPMPDT
VVVPFTTATTGAPEQVTALLAQEVRETTHRALATVQSWLDNGRFAGARLAFVTRGAVAAH
QDTEAGDLAHAPVFGLLRAAQTEHPDRFVLVDLDPGADDIPGRALAGALASTEPELAVRG
GALYAPRLARVTAQAAADATRSRIDARGTVLVTGAGGGLAGLLARHLVTEHGVRHLLLTG
RRGADTDTAAELTAQLGALGAEVTWAACDVADRDAVAALLASVPADRPLTAVVHTAAVLD
DGVVDLLTPERVDRVLRPKVDGALHLHELTRHLDLSAFVLFSAAAGTLGGAGQANYAAAN
VFLDALAQHRRARGLTALSLVWGMWAEERGMAGRLTGAERARAARGGVTPLSARDGLELF
DLALAAEDEPVLLPVGIDLPTLRARAADGGILPMFRGLVRTPSRQRRTAAATPGAHRTEE
TAAAASTGAGEPTLAQRLAELSAAERERTVLNLVRGQVAAVLGYKSAEHVGEEQAFKELG
FDSLTAVELRNRLGAAAGLRLPATLVYDYPNPAALARQLLSEVAPEGTAGRKLSVLEELD
RLESTFASLDPAELSAAADDDAAHARVAVRLQALLAQWNDARQTDGETAADEIEDASDDE
LFALIDKKFGQG
>A0A3G4VNP7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-16|TrEMBL
MANEAKLREYLKKVTTDLDEAYGRLRDIESQAHEPIAITAMSCRFPGGVRSPEELWELLT
SGGDALTAFPTDRGWDLEHLFSDDPDDQGTSTTREGGFLSGASAFDAHFFGISPREAMAM
DPQQRLLLETSWEAFERAGIDPNLLRGSQCGVFVGMNGSDYLTPLLEAAEDYAGHLGTGN
ASSVLSGRLSYTFGLEGPAVTVDTACSASLVALHLAAQALRAGECSLAVAGGVHVMSTPG
LFVEFSKQRGLSTDGRCKAFAAGADGFGPAEGVGVLLLERLSDARKNGRPVLAVLRGSAI
NQDGASNGLTAPNGPSQQRVIRQALANARLSADQVDVVEAHGTGTSLGDPIEAQALLATY
GQDRPADQPLLLGSVKSNIGHTQAAAGVAGVMKMVLAMQHGVLPQSLHIDEPSPHVDWAA
GTVELLTEQTAWPERTHPRRAGVSSFGFSGTNAHVIVEQAPEAEAAGVDGRSGMPVVPWV
LSGKSAGALRGQAERLSGWLAVTADVDPLDVGWSLASTRAGLDHRAVVLGDHAAGVSAVA
TAGLAAGVVTGSVVGGKTAFVFPGQGSQWVGMAAELLESSPVFAARVDECAKALEPFTDW
SLVDVLRGVEGAPSLDRVDVVQPALFAVMVSLAEVWRSAGVRPGAVIGHSQGEIAAACVA
GILSLDDAARVVALRSQAIGRVLAGLGGMVSVPLPAAEVRERIAPWGEQRISVAAVNGPS
SVVVSGEAQALDELLVACEKDGVRAKRIAVDYASHSAQVELLREELAGLLAPIVPQAAEV
PFLSTVTGEWVKGPELDAGYWFRNLRQTVELEQATRTLLEQGFGVFIESSPHPVLTVGMQ
ETVEDAGREAAVLGSLRRNEGGLERFWLSLGEAYVRGVAVDWDAVFAGTGAQRVDLPTYA
FQSQRFWPEAAPVEAGELPVESAIDARFWDAVEREDVTALAEALAFDAPDAIQSLGTVLP
GLSSWRRQSREQSTVDGWRYRVGWKPQADAVTKPRLSGTWLAVVPEAPSDAAGDTVAAVL
RVLAERGAEVRTVTVAAGAAGRDALTATLKAATAGAPAPAGVLSLLALGGDAAAHALSQA
LGDAEVAAPLWCVTRGAVVAGRSDRIADPGQALVWGLGRVASMEQGGRWGGLVDLPGTDA
ADDRTLERLVGVLAGDGAEDQVAVRSSGLFVRRLVRARLAETPAVREWRPRGTTLVTGGT
GVLGGQVARWLAGNGAEHLLLASRRGAEAPGAAELREELTALGARVTLAACDVSDREALA
GLLATVPADQPLTAVIHAAAVVDDGVIETLTAEQVAAVLRVKVDATRHLHELTRDLDLSA
FVLFSSFAATFGAPGQGNQAPGNAFLDAFAEYRRAAGLPATSLAWGPWGSADGDDSAAGD
RMRRHGIIAMPPARTLASLQHALDRDETTLTVVDMDWKRFTLAFTADRPRPLLLELPEAR
RVIESAERESAEDLAGGVPLTQQLAGLPDVEQERLLLDLVRTAVAAVLGHADLTAVEAGR
AFKELGFDSLTSVELRNRLGAVSGLKLPASLVFDHPTPAAVAAYLRAGIVPDAAAGGAPL
LEEIDKLESVLERGTADNVVRARVTMRLQSLLAKWSDTEDPAEEDPADEAEQVQDASDEE
LFALINNGLGRY
>A0A221W4E6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinoalloteichus hoggarensis|TrEMBL
MVRSSGVDRLPWTLSGSGAQSVRGQAGLLLAHLDATPDWRPVDVGHTLAQRPAAGPWRAA
LVAGEAADFRTGLRGLAAGHSAPGLVEGPRVGDSVAFVYSGQGSQWPGMARELSASSSVF
RARIEDCAQALEPFLDWSLLDLLRGAAPELPLDRADVAQPALFAVGAALTALWRSYGVEP
AAVAGHSLGEILAAEASGALSLDDAARVAALWSQAQVTLAGRGEMVSVRASRAEVTKLLR
PWGDALGVAAVNGPAAVIVSGDADAAAEFVAALHADGMTARPVAVGLAAHSAHIDDILPR
LRDDLAALRPREPELPFYSALHGSRLPEGERLDADYWCRNLRGTVRFDEATRAMLADGHR
VLLEMSPHPVLTAAMQEIVEAAEVTASVRGALRRDQADLGRVVHSLAELHVDGVGFDPSV
VFAGHGPLLDLPAVAEDAATDETVSPAEALASLSDGQRRTALLDLVRHEVAVTLGRADGR
LVDPSTPFRDLGFDSITAVEIRNRVGVATGLTLPYTLAFDHPTPAAVADHLHAEFFGVAD
VGDVPPAVSAGADDPVVIVGMACRFPGGVSTPEELWRLCADGVDVVSDFPADRGWDVAGA
YSPTIERPGQFYQGEAGFLHDADLFDAEFFGISPREALAMDPQQRLLLETSWEVLERTGI
DPASLRGSRTGVFIGAMTMDYGPRLDAASGHEGHLLTGNTGSVLSGRIAYTLGLEGPAVT
VDTACSSSLVALHLAVAAVRAGECTSALAGGATVMPSLGMFVEFSRHGGLAPDGRCKPFS
STADGFGLAEGVGLLLVERLSDARRLGHRVLAVVAGSAVNQDGASNGLTAPNGPSQQRVI
RQALASAGVGPSEVDVVEAHGTGTRLGDPIEAQAVLATYGQGRERPLLLGSVKSNLGHTQ
AAAGVAGVMKMVLAMRHGIVPPTLHLDEPSPQVDWSAGTVELVPEAVEWPSTGLRRAGVS
SFGISGTNAHVILAEPPGPVPVSEPTTESEPDESAAAHQPDRDTGRPVGTPAAVEPGAEP
TSTEPPRSEPTGIEQATAETARPDAARGETPEADIAEAGVEPASRDAAEVFSWVLTAKSA
SALRGQAERLLGFVRETDGDLADVAHSLVTTRSVFDHRAVVVGRDRGELTEGLAAIAAAR
SSAFAVTGSPVLGKSAVLFTGQGAQRAGMGRELYASEPVFAAAFDAVCAELDPRLDLPLR
EVVFSDDHELLAQTAWTQAALFAVEVALFRLVESWGVRPDVVGGHSIGEVVAAHVAGVLT
LADACTLVAARGALMQSLPAGGAMASLRASEEEVLPLMTAGVSIAAVNGPRSVVISGVEA
EVSALAARFEKSRRLRVSHAFHSPLMEPMLAEFSEVVRTLEFHAPRIPVLSDVTGGLAEP
EVVCDAAYWVRHVREPVRFADGVRTLQDTGVSVLLELGPAGVLSAMAAESLRAASVAVPS
LLPDRPEASALRMAAARLFALGVPIDRAVLGAAGRRITLPTYAFDRTRYWLEPRTAAAAG
ADGEFWDAVDREDLDALADSLDLGEEERAPLRELLPRLSSWRERGRRRSRVDGLRHRVVW
RPTRQASSARLTGSWVLVSGGDDEDVATALAAAGADVVRLAPTELSTGMPADCAGVVSTV
GLRDTLAVVQELGDRTTPLWCLTRDGVAAPGSDGPVEPWQAAVWGLGRVAALEHPRLWAG
LIDLPARPDEATLRRLAAVLADPAGEDQLALRSSGTFVRRLHRAPSTRGDGGLPTGTVLV
TGGTGALGAAVARLLARNGADRLVLTSRRGVDAPGAPDLAAELRAMHVDVDVVACDVADR
AAVADLLAAHPIDAVFHAAGEIADGVLATMTPERLDRPLAAKARGAAHLDELTRDRELSA
FVVFTSVTGVLGTAGQANYAAANAFLDALAERRRAEGLPGTAIAWGPWAGEGMAAGAVGA
RLAGDGLRPLSVPAALAALRNVLERDETGITVADVDWARFAAHFTATRPSPLLADLPEAA
APADDRGASVGPAALDAADRGRALLDLVRTESAAVLGHRSGADIDVHRVFKDLGFDSLTA
VALRNRMSAATGVTLSAAVVFDHPTPAALAAHLDREMTGRHPEDADAPPAVAEADDPVVI
VGMACRFPGDVRSPEDLWRLLSHGEDAIGEFPADRGWNLDDLYDPTAERAGTSYTRAGGF
LPDAADFDAAFFGISPREALAMDPQQRVLLETSWELFEHAGIRPAALRGERVGVFVGTNG
QDYVTDLAQLPPDVEGHALTGNTASVVSGRIAYTLGLEGPAVTVDTACSSSLVALHLAVQ
ALRGGECTAAIAGGVTVMSRPGVFVEFSRQRGLAPDGRCKSFAAAADGTGWSEGVGLLLV
ERLSDARRLGHRVAAVVRGSAVNQDGASNGLTAPNGPAQERVIRQALANAGLSAADVDVV
EAHGTGTRLGDPIEAHALLRTYGQDRERPLSLGSVKSNLGHTQAAAGVAGVMKMVLAMRH
GIVPPTLHVDEPTSQVDWSAGAVELVTEARPWQTDGRPRRAGVSSFGVSGTNAHVILEAP
PESSAAVPRRQAAGEPAASAVVPWVLTGTSAAAVRGQATRLAEFLRERPALSPVDVGTAL
AARSPFARRVLLAGADRTALLAALAEVAAGRTNLEQPSVGSGVVLVFPGQGSQWVGMAVG
LAAVSSVFAARLGECAEALSEFVDWSLPDVLGDEVALSRVDVVQPVLFAVMVSLAELWRS
VGVVPAAVVGHSQGEIAAAVVSGGLSLRDGARVVVSRSRLIAGLGGGGGMVSVSLPAAEV
VGLLPAGVSLAAVNGPSSVVVSGPRAALAELVADCESRNVRARWIPVDYASHSAAIEEIR
DELITVLAEIDPQPSTVPFYSSVTGAPRATETLDARYWFDNLRETVRFDRAVESLLSDGL
GVFVESSAHPVLTYGVQEVADGRADDQNTLVVGTLRRDDGGLDRFLASAGELFAHGIDLD
LTPFLTGGRLVELPTYAFQRRRYWLDTPATTGDVDAVGLDAADHPLLGATVPVAGTDGLI
HTGRISVAEQPWLADHVVDGAVILPGTAFVELLVRAGEPLGCTRLHELTLQTPMVVPDSG
ALRLQVVVGPSDDDGARPVGVHTRDTDDAAAHWTTHATGLLLPAPPQADFALTQWPPTGA
DPVDVEHVYGGFAEIGMHYGPVFQGLRRAWRRADEIFAEVVLTEEDGATAHRFGVHPALL
DAALHTFALAGIGPQEPILPFAWSDVRFFAAGGAALRVRVRRLGDDTMSIQVADAAGAPV
LSARSLTVRPATAARPGTARRDSLFRVEWLPATGGARRTPVSVIDCHERDPRTAVHRVLA
DLQARLAEDSDDRLVVLTRGAVAVTPEETPDLAGAAVWGLVRSAQAEHPGRIVLLDSDGT
ADPALSAALDEPQVAVRGEQPFVARLRRVSAEGAAAWTAAGPTLITGGTGTLGAAVARHL
VARHGVRDLVLVSRRGPAAPGALRLRDELVGLGAAVAVVACDVSERDQVARLLADHPVDA
VVHAAGTLDDGVVSALTPERVDAVFAAKADAAWHLHELAGELSAFVSFSSAAGVIGSAGQ
ANYAAANAFLDALARHRRAQGLPGQSLAWGLWSQTSEMTGALDAADVTRLQRAGIAPMST
EDGLARFDAALGVDDASPVPFRLDLTAFRHEVPRLFTDLVPARRRATPATATTLSERLAG
LDDTRATALLVDLVRAQAARVLGHATPEAVDTMQPFQLLGFDSLTAVELRNRLNDETGLR
LPATMVFDHPTPATLADFLRERLLGTAAAPAPEAPTTPLSDDPIVIVGMACRFPGGVTDP
DGLWRLLADGGEVVGDFPTDRGWDLDELYDPEPGVPGRSYTRAGGFLADAADFDAGFFGI
SPREALAMDPQQRLLLEASWEVIERAGVDPVSLRGSRTGVFTGLMYHDYASRLPRVPADV
EGYAGNGNAGSVASGRVAYALGLEGAAVTVDTACSSSLVALHLAAQALRAGECDLAIAGG
VTALATPGVFVEFSRQRGLSPDGRCKSFANAADGTGWSEGVGLLLVERLSDARRLGHRVL
AVVAGSAVNQDGASNGLTAPNGPSQQRVIRQALASAGVGPSEVDVVEAHGTGTRLGDPIE
AQAVLATYGQGRERPLLLGSVKSNLGHTQAAAGVAGVMKMVLAMHHGIVPPTLHVDEPTR
EVDWSAGAVELVTEARPWPIDGRPRRAGVSSFGVSGTNAHVILEAPPALAAAESDGDPAA
SDGDGDPTAPHGDPAAPPLVPWVLTGRSPAALRAQADRLARLLQDRPDLRPIDVGSSLAT
SRSLFDHRVLLTGSHRDDFAAALAEIAAGAVPSEERRAGSGVVLVFPGQGSQWVGMAVGL
AAVSSVFAARLGECAEALSEFVDWSLPDVLGDEAALSRVDVVQPVLFAVMVSLAELWRSV
GVVPAAVVGHSQGEIAAAVVSGGLSLRDGARIVVSRSRLIAGLGGGGGMVSVSLPAAEVV
DLLPAGVSLAAVNGPTSVVVSGSEQSLAELVADCESRNVRARWIPVDYASHSVLMDALRD
ELLDVLAGIEPRSSTVPFYSSVTGAAKDTASLDARYWFDNLRETVRFDRAVESLLSDGLG
VFVESSAHPVLTYGIGEVVEEHGAENVLVVGTLRRDDGGLDRFLASAGELFAHGVDLDLT
PFLTGGRLIDLPTYPFQRQRYWLDTPKGFAGDLTSIGQRDTDHPLLGAAVPLADSGGVVL
TGHVSIETHPWLADHAVAGTVLLPGTAFVELAVRAGDQVGCGRVEELTLEAPLVLPRHGA
LALHVLVGAQDDAGLRPVSVYSRRAADDTAWTCHAVGQLGADVPGRDLDLTAWPPAAATV
VPLDGLYERLHDRGYEYGPTFQGLRAMWRTEKEVYAEVTLPDDAITDSPAFDLHPALLDA
ALHPAGAAAATDDVRLPFSWSGVSVHAVGARSLRVRLTLRGEGVVSLDAADQTGASVVSV
ESLALRPVAPEQLAVASTDSLYQLDWSGPREINPSGAATGRWIGGADDLAAPPGESTPDV
LLLDAARAGTADTPARARRAVGTVLDVLRDWLADDDLADTRLAVVTRSAVRAVDDDVPDP
AAAAVWGLVRSAQTENPDRIVLLDVDEPADDRVLVAAAMTGGEQAAIRAGRLYLPQLVRG
GPAESAAPSWGPAGRVLITGGTGTLGAAVARHLVSRHGVRSLVLAGRRGPDAPGAAALRE
ELTGLGADVVVESCDLADRAAVARLLAAHPVTAIVHSAGVLDDGVVSALTPERVDAVFRP
KVDAAWHLHELAGEVSAFVLFSSASGVFGTAGQGNYAAANTFLDALAEHRRARGLPAHSL
AWGWWAATSELTARLGTADRTRLTRRGVVPLSTEEGLALFDAAVAGTRPVVLPVRLDLTA
TLPAVCRGLRRAARRTAAAPAAGEATLLDRLARLDRSDRDAALLNLVRTTAAAVLGHPTL
GEVRPARAFKDLGFDSLTAVELRNRLHRETGRRLPATLVFDYPTPQAIVGFLTDELFGTA
PAQSPVLADLDRLEAGLTDDLDEETRSTITSRLKAVIARWAGDAADGSFVDRLDTASDDE
IFSLIDNRLGRP
>A0A100J4X7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MVSEEKLVDYLKRVSADLHTTRQRLREAEERAQEPIAVVEMACRYPGGIRTPEALWDLVA
TGRHALGPFPENRGWDLAALFHPDPDHPGTTYAREGGFVHDADLFDPEFFGISPREAQAL
DPQQRLLLECAWEALERAGLDPRSLHGSRTGVYAGAALPGFGTPHLDAEAEGHLVTGSAP
SVLSGRLAYTFGFEGPAVTIDTACSSSLVAVHLAAHALRQRECDLALAGGVTVMTTPYVF
TEFSRQRGLAADGRCKPFADAADGTAFSEGAGLLVLERLTDARRAGHPILAVIRGSAVNQ
DGASNGLTAPNGLAQQRVIRAALAGARLSPAEIDAVEAHGTGTRLGDPIEADALLATYGQ
ERHDEKPLWLGSVKSNLGHTQGAAGAAGLIKMVLGLRHETLPATLHVNSPTAQADWASGD
VRLLTEAVPWPRGERTRRAGVSSFGISGTNAHVILEEAPPEEPADEPVRRDPGGRPDLPW
LLSARTVPALRAHAGALAPHLDDPTAAVAATLSHRTLFEHRAVVLGTDREERAQALAALA
EGRPHPALVRPPGAARTGTTAFLFTGQGSQRPGMGQELYAAFPAFAEALDDVCAHLDPAL
KRTLFAPPDSAEAAALNETGTTQTALFALETALYRLVTSFGVTPSHLTGHSVGEIAAAHA
AGVLDLPDACTLVAARGRLMQALPPGGAMLAVQATETDVLPLLTDRLALAAVNGPTSVVI
SGDATQAATLEHTLRARGLRTKRLNVSHAFHSPLLDPMLDEFRAVVRELTFHPPTLPIVS
NLTGALADAQTLADPEYWVRHVRRPVRFFDGVRALDAQKVVRYLELGPDPVLTTMVRDCL
PSTEPVVTTALRTGHDETRTLLSALATLHTDGQPVDFTPLVPPGTDHPHLPTYPFQRRRY
WRSAPHTPTSAVDLDDTGHPLLPVAVQQADGGLLFAGRLSPRTHPWLADHTIGGAVPFPG
TAFLELALSAARFTQCDTIDDLTLETPLLLDDNGTVSLQLTLAAPDSTGRRTLAVHARTD
DEWHRHATGTLTASTDTHPPTPTTWPPTDATPVDVDALYTRLDEQGYAYGPAFRAVRAAW
RHGDDLYADVHLTEPADGFTLHPVLLDAALHAVDTLYPHDDRQVRLPFSFTGVRQYTTGA
TTLRAHLTALADDRLRLDLTDTDGAPVATIDTLRLRRIATGHWRTSIPLHHLEWQQLPFS
FSGEASEAESDFVFAAFPAGDDPAQARTHAHQALRLVSDWLATDTEARLVVVTEGAVTAR
PDDPPPDLATAPLWGLVRAAQAEQPGRILLLDTDQDPASRAAQSAALAAATARNETQLAL
RDGTALVPRLAAVGQSEATAPELDPERAVLITGGTGGLGQTVARHLAAAHGARHLLLAGR
RGPDAEGVAELRDDLAELGVEVEAVACDVTDPEALAELVGSRALTAVVHLAGIVDDSLVT
AMTPDQLDAVLTPKADAAWQLHRLTQDMDLAAFVLFSSAGSVLGAAGQANYATANAFLDA
LAEHRRAEGLAATSIAWGLWESAAGGMAARLDDTDRARIRRTGVAALTDEQALGLFDAAL
TAARPAVLASRFDRAVLRDDMMSPVLRGLVRTPRPAPVTREEETTWAAHVAALPDTDRER
ALTELVREQVAIVLAHPTPGAIELDRAFHELGFDSLTSLELRNRLSTATGIRLPATLVFD
HPTAKALVNHLRAQLPGAGAGAAKAIEATTVRAATDDDPIAIVGMACRYPGGVTSPEDLW
RLVRDGGDAIGPFPENRGWNTAELFDPDPDQVGHSYTREGGFLYDAGEFDAEFFGISPRE
ALAMDPQQRLLLETAWHAFEDAGIDPATLRGTSCGVITGIMYDDYGSRFLARKPEGFEGR
IMTGSTPSVASGRVAYTFGLEGPAITVDTACSSSSVAIHLAAQALRQGECELALAGGVTV
MATPNTFVEFSRQRGLAPDGRCKPFSAAADGTGWGEGAGLVVLERLSDARRRGHKVLALL
RGSAVNQDGASNGLTAPNGPSQERVIRAALAGAGQRAADVDAVEAHGTGTVLGDPIEAGA
LLAVYGQGRAVERPLWLGSVKSNIGHTQAAAGVAGVIKMVMALRHEVLPVSLHAEVPSGH
VEWDGGGVRLLSEAVGWPRGERVRRAGVSSFGISGTNAHLILEEAPGGEEGASVEEPEVV
PWVVSARSSGALEEQVRRVRELEASAVEVGWSLVATRSVFEHRAVIVDGDVVSGVAGDIG
PGPVLVFPGQGSQWVGMGAQLLDESPVFADRIAECEQALAPHVDWSLTEVLRGGRELDRV
DVVQPVLWAVMVSLAAIWEGYGVVPAAVIGHSQGEIAAACVAGALSLQDAARIVAVRSDA
LRQLQGRGDMASIGTGPDEVRALIGDHRPGVSVAVVNSASSTVISGPPAEVAAVVSEAEA
RGLRARLIDVGYASHNAQIDELREELTRRLSDVRPSAVSDVAFYSTVTAGRIDTTALDTE
YWVTNLREQVRFAETIAALQADGYRLFIEASPHPVLVLPMEETIDTGTVVPTLRRDHGGT
KQLTLAAAQAFTAGADINWHRWFPTPPHTIDLPTYPFQHHHYWLAPPTTPTDATDLGMTP
LDHPHLTATTELPASDAYLLTGRLTHETSPWLAEHVVAATPLVPGSALIEWLLRAADEAG
CPTLDEVTLTAPLPFPDSGTTQLQITVGAADDEGRREVRVYARRDTAWVCHATGVASPEP
PVPAAELAPEWPPVDADPVDVEDFYPRAAQTGYTYGPAFQGLRKLWRHGPDLFAEITLPE
QAGPHDGFGIHPALLDAALHPLMLLDPPGNGRLWLPFAWTGVTLSATGATSVRVRLTPRG
ETVGVTITDSTGAPVLTTDALTLRAVAPGQLAAGVEGLYAVEWTPLTAPHDEGEETLVLA
VDGEELPSVAKVLAEVQEFLDSSEESRLTVVTRGAVAVDGGDVDPSAAAVWGLVRSAQTE
HPGRLALLDTDGGELPRLPGGEPQLALRDGALYVPRLTPVTPPDDLLPPPDTSAWRLTTT
GPATLDALAMTEAPEALAPLAPGQVRISVQAAGVNFRDVLIALGMYPDEGTFGGSEGAGR
VTEVGPGVAHLKAGDRVMGLFEGAFGTLVVADARMIVPVPEGMSLREAAAVPVVFLTAWY
GLVELGGLGAGESLLVHAGTGGVGMAAVQIARHLGAEVYATASPAKHAVLAELGIDEAHR
ASSRDLGFAEKFRGRVDLVLNSLAGEFTDASLRLLAGRGRMVDMGKTDKRDAGRVAAEYG
GVPYRAFDLVPDAGPVRIGEMLAELGELFASGALTPLPVRSWPVGRAREAFRFMSQAQHT
GKLVLDIPPALDPDGTVLITGGTGVLGTAVAEHLVREWGVRRLVLASRSGGGEGVVEGLD
ADVSFAAVDVTDADAVAELVACIEGLTGVVHAAGVLDDAVVTAQTPESLAKVWAVKAAGA
RHLHEATRDLGLDLFVVFSSAAATLGSPGQANYAAANAYCDALMQHRRAEGLPGLSIGWG
LWRTASGMTGHLNDTDLARMKRTGFTPLTTEHGLALLDAARAQERPHVIAVDLDVRAVAA
PPPPLLRALATKAVTARRTAATGTAAVDGFADRLAALPPAGRHRLLLDLVRSHAAGVLGH
ADHDAIRPDTSFKELGFDSLTAVELRNRLAAATGLKLPAALVFDHPESSALAGHLLERLD
GTPAPPKDPVGPLLGELGRIESSLTTLALDDEARGRITRRLTTLLTKLNGAPDLEALDTV
SDDEMFELIDREL
>A0A100J529|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MASEEQLVDYLKRVAAELHDTRQRLRELEERHQEPVAVVGMACHFPGGVETPEDLWDLVA
AGADAIEPFPTDRGWDLERIYHPDPENPGTCYVREGGFLAGADRFDAEFFGFSPREALAS
SPQLRILLETAWEALERAGIAPTSLKGSRTGVYIGSGTTGNQTQGDLEGKSSEGYAGTAP
SVLSGRISFNLGLEGPAVTVETACSSSLVAMHLAAQALRQGECELALAGGVTVTSTPEVF
TGFARQRGLAPDGRCKPFAAAADGTGWGEGAGLLVLERLSSARRNGHRVLALLRGSAVNQ
DGASNGFTAPNGPSQRRVIRQALASAHLSTSEIDAVEAHGTGTRLGDPIEAEALIATYGK
DREDDRPLWLGSVKSNIGHTQAAAGVAGVIKMVMALRHELLPVTLNVDEPTPHVQWDGGG
VRLLTEAVEWERGERVRRAGVSSFGISGTNAHVILEEAPLSDEASLAGEVSSVEEPELVP
WVVSARSEAALEEQVRRVRELEASAVEVGWSLVTTRSVFEHRAVIVDGDVVSGVAGDVGP
GPVLVFPGQGSQWVGMGAQLLDESPVFADRIAECEQALAPHVGWSLTEVLRGGGELDRVD
VVQPVLWAVMVSLAAVWEGYGVRPAAVIGHSQGEIAAACVAGVLSLQDAARIVAVRSDAL
RQLQGRGDMASIGTGPDEVRALIGDHRPGVSVAVVNSASSTVISGPPGDIAAVVSEAEAR
GLRARLIDVGYASHNAQIDELREELTRRLSDVHPVAVSDVAFYSTVTAARIDTATLDTGY
WVTNLREQVRFAETIKALQADGYRLFIEASPHPVLVLPMEETIDTGTIVPTLRRDHGTTH
QLTLAAAQAFTAGADINWHHWFPTPPHPIDLPTYPFQHHHYWLEVDTQGDARSMGLRRLE
HPLLPAILSLADGALVLTGRLAASSGWLAEHAVAGTALVPGAALVEWALRAADESGCAGL
EELTLQAPLVLPESGGLQVQVAVGAADEQDGRRELSVFSRPESGHDESWTCHAVGVLTPE
PGDAPDELSGPWPPAGAEAVDIGDLYERAASAGYTYGPAFQGVRAVWRHGQDLLAEVELP
GRTGADDGFGIHPALLDAALHPALLLDPEDPDGQELRLPFAWTGVSLWATGATAARVRLS
PHGDTLRVTVADSAGTPVLGVDSLALLPVDPERLRSAARTGVDGLFTVEWTSVSGTAVED
LDCVTLGRDVPDLAALSEGRIPATVLVEVGVPSEGTVDERGRAVTEYTLRLIQDWLAEPR
LADARLVLITRQAVAVQNTESVDAPAAAVWGLIRSAQAEHPGQFVLLDTGTGTGTDAGTD
PGGDRTTLARALATGEPQLAVREGRPLVPRLTRATLPASTGPVLDPDGAVLIAGGTGMMG
ALVAEHLVRAWSVRRLVLAGRQGPDAPGARELAERLTGLGADVRIVSADLADAQATAELV
ASVDRLTGVIHAAGVLDDAVVTAQNSDRLATVWAAKASVAAHLDAATAHLPLALFLTFSS
AAGVLGNAGQAGYAAANAFVDALVTHRRATGLPGLSIAWGLWARGSAMTRHLDDTDLARL
RAGGLKPLLDDQGLALLDAARATADDTPMVVAAGVDVRALTADSVPPILRNVAGRIRRRA
AVGSAADRAELETRLAGLDEDGRLRVVTDVVRESVAEILGYRSADDVRVEANFKDLGFDS
LTAVQLRNRLSAVSGVRLPATIVFDHPTPRGLAAYLDTRLGGRVSAAPVAVPVSTGDDPI
AIVSMACRFPGGVNSPEELWELVVGGVDAMGAFPTDRGWDLENLFHPDPDHPGTSYADEG
AFLPDAGDFDAGFFGINPREALAMDPQQRLLLETSWEVLERAGIDPTSLKGSRTGTYAGV
MYHDYAAGLTDGDGYAMLAGAGSVVSGRVAYTLGLEGPTMTVDTACSSSLVAIHLASQAL
RQGECDLALAGGVTVMATPEVFVGFSRQRGMAPDGRCKSFAAAADGTGWGEGVGLVLLER
LSDARRNGHRVLAVVRGSAVNQDGASNGLTAPNGPSQERVILAALASGGLSTGDVDVVEG
HGTGTTLGDPIEAGALLATYGQGREVPLLLGSVKSNIGHTQAAAGVAGVIKMVMALRRGV
VPGSLHVDAPSPFVEWELGAVRVVGENEAWPEVGRVRRAGVSSFGASGTNAHLVVEQVPE
EEGAVERREGGVVPWVVSARSEGAMREGGVWSAGKRVNCWPRSPRASRADRSPPAVRPVT
PS
>A0A100J467|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MSDSIEKYVEALRSSLKEIDRLRKQNEQLATAKVEPVAIVGIGCRFPGGVSSPSDLWDVL
VGGVDAISGFPVDRGWDLTDGGSGKGGFLHDAAEFDAGFFGISPREALAMDPQQRLLLET
AWEALERARIDPHSLKGSKTGVYAGLMYHDYSEPLRAAADEIGGILGIGTAGSVLSGRVA
YTLGLEGPAVTVDTACSSSLVALHLAAQALRSGECDLALAGGVTVMATPGAFAEQGGVAR
DGRCKSFAASADGTGWAEGSALVVVERLSDAQRNGHRVLAVVRGSAINQDGASNGLTAPN
GPSQQRVIRQALASAGLTAAEVDVVEAHGTGTRLGDPIEAQALLATYGQGRPEGRPLWLG
SLKSNIGHTQGAAGVGGVIKMVLAMQHGQLPRTLHVGEPTPEVDWSAGAVELLTEQRPWP
VVGRPWRAGVSSFGVSGTNAHVILEQAPESEPTARVEAEPVVVPWVLSARSELALREQAR
RLLAHVEAGPGLDPVDVGAALVSTRASLEHRAVVLGADREQLIARLAGLAAGEPGAGVVA
GQSAVSGRGVVFVFPGQGAQWVGMGQGLLTASPVFAERMAECARALAPFVEWDLLEVLGD
EEALGRVDVVQPVLWAVMVSLAQVWQSLGVTPVAVVGHSQGEIAAACVAGGLSLDDAARI
SAVRSRMIAGSLAGRGGMVSVGLPRAEAESLIVRWEGRLSVAAVNGPSSVVVSGDPEALA
ELVVAGEAENFRARRIEVDYASHSAHVEEIRAELVEALADIAPMEGAVAFYSTVTGELTD
TRDLDAGYWYRNLRETVRLADTTRALAAAGHGAFVEVSPHPVLTPSLEETLFESHPAVVV
TGTLRRGESESEQLLAAAARLHTRGVPVDWAAIVGRGPVVDLPTYAFQRERYWPEAAAGP
VVAGADDELWSVVEGADAGSLSAELGVDEQALAEVVPALAVWRERRRAGSRVEGWRFAES
WKLLPGVPGGVLPGSWLVVVPAGWGEDAWVAGVVGALGAGVVRLEVAGDTDRAVLAARLA
NLPEPAGVVSLLGLAEEAGAEFGATPVGLAGTVGLVQALGDCGITAPVWCVTRGAVSVGS
ADPVVSPVQTALWGLGRSAALDLPGRWGGLVDLPVVFDEQAGGLLRRVLTGDEDQVAVRE
SGVYGRRLVRAGSGAAHGEVRLSGSVLITGGTGGLGGHVARWAVARGAEHVVLVSRRGEQ
ADGVSGLREELIAQGARVTVEACDVADREALAAVLGAIPGEFPLTAVVHAAGIGDHHAPV
GELELGRLDAVLRAKMVSAWHLHELTAGLELQAFVLFSSGAASWGAGGQAAYAAANAFLD
GLAGYRHGAGLAATSIAWGLWAGPGMGAAGAEFVEGYRRRGVFPMEPGLAMAALERAVGD
GSVTLTVTNTDWETFAPSFTVERPSALLSGIPEVRKALALSGVQPGGESALRSRLAGLGE
RERARALLDLVRREAAVTLGFDNADALPQGRAFRDVGFDSLTAVELRNKLASATGLVLPA
SLVFDYPTPAALAEHLGSELLGTVEAAPVTPVITAALDEPIAIVGMGCRFPGGVSSPEQL
WNAVVSSVDAMSEFPADRGWDLVGDGFARVGGFVEDVAGFDAGFFGISPREALAMDPQQR
LLLETAWEALERTGIAPNALKGSKTGVFVGGAVSGYETVGNVSDEADGYRITGGASSVLS
GRIAYVLGLEGPAVTVDTACSSSLVALHLAAQALRSGECDLALTGGVAVMATPGAFAEFA
TQGVLAGDGRCKSFAASADGTGWGEGAGLLVVERLSDARRNGHRVLAVVRSSAINQDGAS
NGLSAPNGPSQQRVIRQALASAGLTTAEVDVVEAHGTGTRLGDPIEAQALLATYGQDRPE
DRPLWLGSLKSNIGHTQAAAGVAGVIKMVLAMQHGQLPRTLHVDEPTPEVDWSAGAVELL
TEQRPWPVVDRPWRAGVSSFGVSGTNAHVILEQAPELEPASRVEAEPSVVPWVLSARSES
ALRDQARRLAAHMEADPELDPVDVGAALVSTRAGLEHRAVVLGTDRDELIARLTGLATGE
PGTGVVTGIAGQTGEREVVFVFPGQGAQWTGMAQELLAASPVFAERMAECAQALAPFVDW
DLLEALEDQEALGRVEVVQPVLWAVMVSLAQVWQSLGVTPAAVMGHSQGEIAAACVAGGL
SLADAARIIAVRSRLLAKSLSGRGGMVSVRLPRAEAESLITRWEGRLSIAAVNGPSWVVV
SGDAEAVTELVVAGEAEDFRTRRMDTDCAGHSPQVDEIKAELIEALADIAPMEGTVAFYS
TVTGELTDTRDLDAEYWYRNARETVRLAETTPVLATAGYEMFVEVSPHPVLTPSLEETLF
ESHPAAVVTGTLRRGENEPEQLLTALSTLHTHGVPVDWSAIVGQDSTVELPTYAFQHQRY
WPRPRTVAGDARGMGLTSVGHPLLGAAVELAGGEGVVFTNRLSLTSHAWLADHTARGVVL
LAGTAFVELVVRAGDEVGCGVLEDLALERPLVLSERGAVQVQVVVEAPAESGRRAVSVYS
RPEETGTEAGWTRHASGTLTSEAGAPSGVELTVWPPAGAEPVPVDGFYEALAETGYGYGP
AFQGVRTVWRRGEEVFAEVRLPDEVAERAGEFGIHPALFDAALHAAAFLPAGGEGGLPFS
WSGVSLHASGARSLRVRLSETDDGALCLNAADDTGAPVLSVDSLTLRPLRAELLDGDAQR
SLFSVDWTLKPAVPTGTENSPRCVVAGAGGQDLAKMLGVAWYPELSECPETDLVLLPTGA
DADDGDVAAAARSEVCRVLELVQEWVADERGDARLVVVTRNAVSTGTGDRVEDMAGVQGL
VRSARSEHPGRFGLVDVDGSAESWQCLPAVLSETTDDEGDFELAVRAGQAYTPRLTRTRE
VLTAPMETWRLGMTGQGSVDDLVLEPSPEAEVPLEAGQVRIGVRAAGLNFRDVLNVLGVY
PGEAPLLGAEVAGVVLEAGPGVTGFVPGDRVMGMAVGGFGPVVAADARLIVPIPRGWSFA
QAAGVPVVFLTALYGLRETGRLTAGQRVLVHAAAGGVGMAAVQLARLWGAEVFATASPGK
QDTVYGLGVARDHIASSRTTEFADRFTGMDVVLNSLAGEFIDASLNVLRDGGRFVELGKT
DLRDTDAIATTHPGVSYHAIDLEIDLDVVGGMLAELAELFESGVLSPLPTRTWDVRQSRD
AFRYMAQARHVGKIVLTVPQQLDPDRTVLITGGTGGLGGLLARHLADRHGIRHLTLVSRQ
GIAAPGAQELVEELTALGAQVRVVACDVSDRNAVTELIAGVPQQHPLTAVIHAAAVLDDG
TITSLTPERIDTVMRPKADAAWYLHEATAGLDLAAFILFSSFSATSGAPGQGNYAAANAF
LDALALHRQVQGLPAASLAWGWWADTSSMTGLGHTDHARFGRAGVRAMPAAEGLALFDLA
CRRPEAYLVPVGLELPRNGGSVPPLLRGLVASGPARPVARAGVQDSSGLVRRLAGLTAAD
QQRLLLDLVCGHVATVLGHASVEAVDPEKALRDMGFDSLTTVELRNRLAAATGLRLPATL
AFDHPTTSRLATHLRQQLLGTVEAVSVTPVTTAALDEPIAIVGMGCRFPGGVESPEQLWT
LLTGGIDTISAFPTQRGWDLTGDGATQTGGFLKDVAGFDAGFFGISPREALVMDPQQRLL
LETAWEALERSGIDPNTLKGSRTGVFVGGTGSGYDTVGDAADQVDGYLLTGAASSVLSGR
IAYTLGLEGPAVTVDTACSSSLVALHLAAQALRSGECSMALAGGVTVMATPGVFIAGSAM
QGGVGGDGRCKAFAATADGFGVAEGAGLLVVERLSDARRNGHRVLAVVRGSAINQDGASN
GLTAPNGPSQQRVIRQALASAGVPTTEVDVVEAHGTGTRLGDPIEAQALLATYGQDRSED
RPLWLGSVKSNLGHTQAAAGVAGVIKMVLAMQHGQLPRTLHVDEPTPEVDWSAGAVELLT
EQQPWPAVDRPWRAGVSSFGISGTNAHVILEQAPDQAPDLEPAPDVEVVPWVLSARSESA
LRDQARRLLAHVEANPELDPVDVGAALVSTRASFGHRAVVLGTDRDQLIAGLAGLAAGEP
GAGVASGVSAASGRTAFLFTGQSAQRLEMGRELAAEFPVFAEAFDEVRARFAEWLPGSPE
PAATDDGLADPAWAQATLFAFEVAMFRLLSSWGVTPDYVAGHATGEAVAAYVAGVWSLDD
ARRVLTAGDDENGTAPTESPGPSRIVLVSLESGEPVQERPEFAVADTQRPARFAEAVGWL
REQGATRFVELGPDAALTGLRPDGVDAEFVAMQRQDRPQVYEAMAALAFLYTRGVTVDWR
AMFARSGARRVELPTYAFQRERFWSLASGTGGVAGAGLSTAGHALLGAVVRLADRDELVF
TSRLSQATHPWLAEHHLGATAVLPVTALVDIAMRAGDEAGCAVLEELTVHAPLVIPDHGA
VQVQVVVGSPDEEGRRPIVVYARPENTDDEWLSYATGLLAALGGEPGWTERTWPPADARP
VPVEDAYDLLAERGHRYGPVFQGLRAVWRRGDVVFAEVALPQRAAGDSARFGIHPALLDA
ALHPLLIASEDVRLPSTWTNVSLHTTGTTALRVALTPAGDDDGYRLDVADEVGNAVATAR
LSRWERVSTGQRGDEDDLLRVEWAPVGSLEDTGEHEDSVALLGEVSSELSEAGFLRFGDI
TEAALSYEPWDILVAESPADGELPSVAHRAVRHVLTRLQEWVTRDDLPDNRLVVVTRGAV
AASEGEAVVDLAGAAVWGLVRSAQSEHPDRITLVDIPDGGSVPWARIAAAAAIEPQLAVR
DGELLVPRLVRTTGAGTARPALAGQGTVLVTGGTGALGALFARHLVTRHGVRHLVLASRR
GAQAPQADVLRETLAELGAQVEFVACDVADRESVAHLLAGIGEEHPLVGVVHAAGALDDG
VVTSLTGERVTEVLRAKADGAWHLHELTQHLDLDLFVLFSSVSGVLGIPGQANYAAANAF
LDGVAEHRRARALPAVSLAWGLFDDTAGAAKQLGLKPITTETAVRLFDQALHDGSAAVVP
APLDLGRLGQESVRVPTLLRSLLPARGTGSVAGAEESLTERLAGMPRSEAEQYVRDLVRR
ETATALGYASAGEVAPEVSFRDAGFDSLAAVRFRNQLVDKTGLALPTTLVFDHTSPAVLA
DHLVGRLVVTGESPEQAVLAELDRLEAVLMSMPGGDPETEAIGSRLDAVVSRWRTAFRPS
GTDDHAETVTKLQDATEEEVLDFIDRQFRRDER
>Q3M9X9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Trichormus variabilis (strain ATCC 29413 / PCC 7937)|TrEMBL
MEKIAIIGLSCLFPDANNPEQFWQNLTEQKDSTSSVTVAQMGVDPTIFYDPVKGKPEKFY
FLKGGFIQNFQFDASEYNLPSEYVESLDNTFKWSLYAAKQAIKHSGYWGNQDVLSKCGVI
LGTLSFPTKLSTQLVTPIYRQTIEPAVAELLQNQDFHLAALPTATKPSLHNAMISGLPAA
LVAQAFSLSGTHFCIDAACSSAFYAIKLASHYLWTGKADVMLAGAISCSDPLFLRMLFSG
IQGYPENGISSPLDKSSRGLVTSEGIGMVMLKRYSDAVRDGDKILATVCGNGLSNDGKGK
HLLSPNTKGQVTAFERAYKEAQLSPKAIDYMECHATGTLLGDTTEFNSIESFFGEHQAAP
LIGSSKANVGHLLVAAGMVSLTKAIYGMNYGVIPPTINVNDPIGTENNVISPQNIVRTPT
AWPINTGTKHAALSAFGFGGTNSHLILEKAADL
>G2NJK5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. (strain SirexAA-E / ActE)|TrEMBL
MNNEEQLLDYLRRTTADLREARRRLRENEQRAHGPVAVVGIGCRYPGGVTSPEDLWNLVA
TGTDAVAEFPGDRGWDVEALYDPDPDRPGTTYARTGGFLYDAPDFDYDFFGISPREALAM
DPQQRLLLETSFEAFERAGIVPASLRGSRTGVFAGVMYNDYATRLDTVPDDLDGYLANGS
AASIASGRVAYTFGLEGPVVTVDTACSSSLVALHWAVRALQAGECSLALAGGVTVMSTPE
TFVDFSRQRGLAPDGRCKAFSTAADGTGWGEGAGMLLVERLADARRNGHPVLAVVRGSAV
NSDGASSRLTAPNGPSQQRVIRQALAGAGLTAADVDVVEAHGTGTSLGDPIEAQALLATY
GREHPADRPLLLGSVKSNLGHTQAAAGVAGVVKMVMAMRHGEVPPTLHVDTPTDQVDWDA
GAVELALEKRPWPETGGPRRAAVSSFGISGTNAHVVLEQAPLEEEPGTGTAPAPAGAEPR
ASAIAATPVPWIVTGRSPEALAGQIARLREHLTGRDDAPADIALSLATTRTHFEHRAVAV
GQDTGALLDALATASPLTPVGGRTAFLFTGQGAQRPGMGRALHRAHPVYAEAFDAVCALA
DPHLERPLGEVIDGDPALLTRTDYAQIAIFATEVALYRLLESWGVVPDYLAGHSVGELAA
AHVAGVFSLPDAVSLVLARGGLMAALPAGGAMAALRATEEEVAPYLDERVGLAAVNGPRS
VVVSGTEEAVDALAARFERAKRLTVSHAFHSPLMDPMLDAFAEAASRCDYREPRIPVVST
LTGVLTTPGELTTPGYWVDHVRRPVRFAPALATLHDLGVRAFLEVGPDAALTSAAAECLP
PDSVCVPGLRRDGDETHDVVTSVARLHAAGGRVDWKAFHAPHHARRTDLPTYAFRRTRLW
LEAAPGGTGDAEGLGQEATGHPLLTAATELPDTQGTVLTGRLSLSSQPWLGDHAVHGTVL
LPGTAFVEMALRAAAQTGCDTVGELTLHAPVTLPEHGSVAVQVAVGAERDGRRELTVWSR
RTDTPWTRNAGGFLATTADEAPPADPGTWPPAGAEPVDLDGLYTQLARTGYGYGEVFQGL
RAMWRRGEELYAEAALPDGARATAGAFGLHPALLDAALHVNLLDLPGGQAVLPFAWSGVT
LHRTGTDRLRLRLSPAGNDAVRLDLADQHGTPVATVRGLVARPVTADQLTADADDPLYRV
DLVPVTGAAHPAPSGLAVCGADAGLDAPRYRDLAALADAGEVPDTVVLAVPADAVAGADL
PRRARELVGTTLERLRHWLDDARFTGRRLAVLLRDDHLAHAPLFGLVRAAAAENPGRFLL
IGTDGSAAPDAALATALASGEPETVVRDGEVRVPRLARAKPGGPRGWDPDGTVLITGGTG
GLGALIARHLVTEHGVRRLLLAGRRGPDTPGAAELRDQLATLGAEVTLARCDVADRADLA
DLLDRHPVRAVVHAAGVVDNGVLTSLDADRVERVLRPKVDAAWHLHELTRESDLSAFVLL
SSAAGLLVGGGQANYAAANTFLDGLAAHRRSLGLPAVSLAYGLWEADGGMSAGIDAADLE
RLRRLGLPPLAPAQGLRLFDAALGAEDALVVPVRLDGAAVRARPDGVPALLRGLVRPAAR
TPGAGATDGPPSAPWRERLAGLPDTERDRALLDLVRTHVARVLGHPSPQSVDPGRAFQEM
GFDSLAAVELRNLLAGATGLTLPATLVFDQPSPRTLAAHLKTELVPGPADLTRSALADVD
RVEAALLALPDEDGSHARVTARLEALLRGWQDARDAAPESPQDFGEASDAELFARIDNEL
GAL
>A0A4R8R952|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides franklinii|TrEMBL
MSAADADPVVISGMAIEAPGGIDTPTAFWNALADGSELIGPFPRDRDWPIEQLLSLSNLE
GWGRVSDAGGFLTDASAFDPTFYGITQREAVAMDPQQRLAMRVAWKALENTGLNPGSLDG
SEAGCFIGISPNEYGPPTGEINAHNGMRVVGRGQLGAAGRISHGLGLIGPSVCVDSACAS
SLAALHIAAAAVRAEECEWAIAGGVCVMGSPGGFYEFSRMHALDPDGHCRSYSDEANGTL
WGEAVGMVVLERESRARALGHRVYGRIMAIRTNHNGGGKPILVPRGRAQAKLVAATIAAS
GVDPADIGMLEGHGTGTRAGDPLEIMALQSTYGAGGSNALLGSAKSNAGHAQSAAGMVGL
IKLLLSGQHGHIPPTLFADNPTTKIDWSMTGIRLATKLHPWEPRNGIRYGAVSSFGAGGA
NAHAIIAMPAMDTEGEDGDDF
>A0A655FCI8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium tuberculosis|TrEMBL
MISNAAAVLGRSSSVDINAHKAFQDLGFDSLTAVELRNRLKTATGLTLSPTLIFDYPTPA
TLAEHLDSRLVTASGSDQQSLSDRVDDITRELVVLLDQPDLSANVKAHLRTRLQTMLTSL
TTEDDDIAAATESQLFAILDEELGS
>A0A653FPN8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium smegmatis|TrEMBL
MVSAEHPIEPTPSFAIIGYAARFPGAASAEEYWALLRDGREAISDVPKDRWDIEEFFDPD
PSTPGKVVTRRAGFVDDVTGFDAPFFGMSAREVRLMDPQHRILMETAWRAVEHSGIAPTS
LANSNTGVFVGLATHDYLGMASDELTYPEIEAYMAIGTSNAAAAGRISYRLGLQGPAVAV
DTACSSSLVAIHQACQALRLNECDLALAGGANVLLTPATMITFSNAHMLAPDGRCKTFDA
AADGYVRGEGCGVVVVKRLEDAVRDGDRIRAVIRGSAINQDGASGGLTVPNGVAQQRVIA
DALKRAGLRPADVGYLEAHGTGTSLGDPIEAQAAGEVLGAGRAPEEPLLIGSAKTNIGHL
EAAAGIAGVIKVVMALENETLPKHLNFETPSPHIPWERLPIEVVRETVPWQRNGKPRIAG
VSSFGFAGTNAHVILEEAPAVGTPATTEPVEDPRRYSVLPLSARTPEALVRLAGEYRDWL
RAHPQARLADVSHTAGTARAHLEQRAALVVNSRESAIELLGALADDRPAPGLVRGESHEA
PKTAWLFTGQGSQYPGMARELFDTEPVFAETVRKCAEAVADILEKPLLDVIFDADELDGD
TESPLRHTTYAQPALFAVELGLARLWQSWGFEPDVVVGHSVGQYSAACVAGVFDVEDGAR
LIAERGRLFGSLPAGGRMAAVFTAPERAERLTDEYPSLSVAAYNGANTVLSGPAKDLESA
VATLVADGVRCDWLDTSHAFHSALLDPILDDFESFAQKLEYREPQRILIDNRTGSALGRS
TRLDGAYWRRHARQPVEFAKSVRTLADMNCRVLLEIGPRPVLTATALAAWPDPATTPQVL
ASLRPTTADHRQITEAVAAAYAAGHLPDFRAFRQPDARKLDLPTYPFEHRQFWFSDNRAI
DRDTQTASAGSVTPHRTQAVRLLEDGQIEELAALIDGETVDEQTLRVLNKLAARHNQQRS
THVDPDARYEIRWDAIASAAASTGAAADWILVGDDTAAVLEFADALTAGGHRHQIVALPG
SDADEAQLVDTLRAASAGELYVVHIAAGDGAAAPMRDLLRVQHRTLGGLRRLFRAANDAE
LRSPIWLVTRDGQRVTDTDTVVPEQSCLWGFGRAAALELPHIWGGLADLSGADTEWPRLI
ARITSPRDGEDQIALRGDAVYAPRLVRRTGEPSDTPLPVREDRTYLVTGGLGAIGLEVAG
YLASHGAGHVVLTSRREPGDDARRRLDGLREQYACDVRVITADVADAHDVARLMTTVAAE
LPPLAGIVHAAGEIGTTPLSGLDDAEVDRVFAGKVWGAWHLSEALTDLRTDLDFFVSTSS
IASVWGGFGQTAYGAANAFLDGLAWRLRERGVTAVSVNFGPWAAGMADAESRARLEQRGV
RTLSPAEALAGMADVVAGPVQGVVAKIDWSRFLPLYQQAGRRAFLSELESELPAAATGAA
APATVPGKPPLVEQLTKAPVQQRKSLITNYLRNAVAEVTRVDADEIRDEAGFFDLGMDSL
MAVELRRRIEQGVGKDIPVTLVMDHPRLSDAADYLLVEVLGLGEQTNVRQASTVTARTDD
PIAVVAVSCRFPGAPDPESFWELLAGGVDAIREVPEDRWDIDEFYDPDPDTPGKTYTRFG
GFLDGIDGFDPEFFGISPREAVWIEPQQRLMLETVWEGLERAGYAPSDLRGSRTGVFTGV
AANEYAHLLSAESIDKIEPHFITGNALNAISGRVAFALGFEGPAVAVDTACSSALVAVHQ
ACQALQSGDCDLALAGGVNVLLSPVTVVAASRARMLSPVGRCKTFDASADGYVRSEGCGV
LVLKRLSDAVRDGDRVCAVIPASSVNQDGASSGLTVPNGGAQQRLIEATLARAGLSGADV
DYLEAHGTGTPLGDPIEVQAAAAAYGAGRDADRPLLMGSVKTNIGHTESASGAAGLIKVV
LSLQHGVLPQSLHFENPSPHIPWDALPVRVIDEPVPWQTNGRVRRAGVSSFGFTGTNAHV
LVEEAPPQLHTADAAPVEPAATAEAGTDDSPQVLALSARSPEALVELARRYDDWLSATPG
LDIADVCHTAGVGRSHFEYRAALVVDSVERAREGLAALAEGRTPAGVVRGEHVHRPTTAW
LFTGQGSQYPGMARELFDTQPVFAQTVRQCAEAVADMLPRPLLDVLFATDRETADLLQHT
SFAQPALFAVEMGLARLWQSWAIEPDVVLGHSVGQYAAACVAGVFSLDDGARLMAERGRM
FGSLPEGGRMVAVFADAEHVEQVAGEFPRVSVGAYNGPNTVLSGPGEDLEEIVERFEDEG
IRCTWLATSHAFHSELLDPVLDEFEAYAAQFQFAAPTLPLVCNRTGAVLTGQTPLDAQYW
RRHSRQPVQFAESVRTVAALGCSVLMEIGPQPVLTGAAVQVWPEHMAAPRAVASLRKGVA
DRRQIADALASAYVGGHRPDFAAVHRQPRRPVELPTYPFQRRRFWPKASSIAVDGGTAAS
GILGSGKDLASGDTIYTSRLSVKSQPWLADHVIYGTVVVPGATYAAMALAAVGTPARLKD
VFFYEPIILPEKASREVQLTLHPADGGSVLSFQIHSRPYGERGADWSLNAEGTVDTAGSD
PDAAADEQSDPVDEVIERLERMRPQDLFETFADLELAWGPTWSGSLKSLWLGDGEAVGDI
LVGAELAEQLGSEPMHPVLMDLCTGVAFPAFPALLAAEQGVNDLFLPLRYGQVTLAEKMP
RRFYCRARWHRSALDSETQVFELEFVDLGGRALGGIREFTVKRAPREALLRGLGGDATRL
LYTLGWHEVPPPPSADDAVGTWLIAGFDELAAKVPGCVPIDRNTDLQVLGEVLSQAHARG
AGFSGVVWRCATPGRKESGSASAESARLEAEITNLLSAVHAAQGPSVKLPGGLWIVTEHG
VACESGEPVDPVQAALWGFGRTTINEEPALHCRLVDCDGSSEAVDLLAALLAAPGIQEPE
IAVRQGKLLASRLLPWARSGHLTLPRGGDFVLAPTERGAIDNLRLTETDVPEPDEGYVQV
RVEAAGLNFRDVLNVLGLYPGDPGPIGGDFAGTVTQLGAGVSGLEIGQRVYGSMQGAFAS
RFNVPAQFLAPIPDGIGAVEAATIPAAALTVRLAFDWAQLKPGDKVLIHAASGGVGLAAI
QMAQQSGAEVFATASTFKRSTLRRLGVKYVYDSRTTDFADQILADTNGAGVDVVLNSLTS
AGFVEATLKATAQGGRFAEIAKRDIWSHEQMAEARPDIAYEIVALDTVMFTEPDRIRDLL
TEVSDGMARGEWTPLPAEIYPITEARSAFRRMQQARHIGKIVLQVPKPLQPQQDRSYLIT
GGLGAIGLHTAAYLAQLGAGDIVLTSRRDPDESAQRAIDEITERHKCRIHTYAADVGDEA
QVADLLARIRAELPPLAGIAHLAGVLDDALLSAQNPERFRTTLAPKAYGASHLDRLTRDD
DLDFFIVSSSVSSLFGSPGQANYATANAMLDGLVAKRRAQGLVATGINFGPWGQGGMASS
EAATANITAQGLIPLDPSAALHALAEVIANGSGQATVLKANWQRAAKVLGSARPPILDLV
LPSAAGEATGDSELLKQLMEIPIPQRAGFVTEFLQREVQNFLRLASPPAASSRFLDLGTD
SLMAIELRNRLHSQFGGKFTINATAVFDYPTIGGLAEYLVGQLPDAEAPETA
>K9XVV6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Stanieria cyanosphaera (strain ATCC 29371 / PCC 7437)|TrEMBL
MNSGASLNTEESIAIIGMDGRFPGAKNIEQFWENLKAGRESITQLTDDQLLASGVDKTVI
NDPNYVKAGAFLEDIDLFDANFFGYNPQEASALDPQHRIFLECAYSALENAGYNPDKYTG
KIGIFAGVGWNNYLLFNLNPNEDFFKTALGYQTIIGNEKDFLTTRISYLLNLTGISIDIQ
TACSTSLVTTSMACQSLLTYQSDITLAGGISISNLKKTGYLYQEGGILSPDGHCRAFDAQ
AQGTVPGSGVGVVVLKRLEDALADGDCIHAVIRGSAINNDGAGKIGYTAPSIDGQAEVIA
EALALAEVEPETISYVETHGTGTPLGDPIEIAALNQVFGVRKGNSRIALTECALGSVKTN
IGHLDAAAGITGLIKTVLALKHKQIPPSLHFQQPNPKIDFTNSSFYVNTELREWKTPGYS
RRAGVSSFGIGGTNVHVVLEEAPYLVGAIHESPLQKLLMISAKTESALDTATDNLVEHLQ
KHPELDLADVAYTLQVGRKEFNYRRMVVGQDVEDIAIALQSRNPQRVLTHCTQQERYSIV
FMFPGQGSQYVNMGKELYETEPVFREWIDRCCQLLEPELGLDLRSLLYPIGAIRESPLPN
SPLQQTEITQPALFVIEYALAQLWMSWGIKPQAAIGHSIGEYVAATLAGVMSLEDALHLV
AQRGKLIQQMPPGSMLAVSLSEAEVRTIHELSLLNDELSLAASNAPNLCVISGNTEAIAR
LENQLNEQGIECRHLHTSHAFHSSMMNDAIAPFQQEVAKVKLNPPQMPFISCVTGTWITA
EEATNPHYWAKHIRETVRFAAGVDRLLQNSHQILLEVGAGRTLSTLVRRNSSQATGQIVL
SSLPHPKEQVSDHAFILNMLGRLWLAGVEIDWCNFSAHQKRRRVPLPTYPFERQRYWIDS
KEAEAPRSKGVEENIAKKVNLSDWFYVPAWKSVPLIQTNDLSKESYLIFVDSSGIGKQLV
EQLRQNGTEVSTVYCGDKFSQHDHNYKINPTNPEDYHSLLKAISLTSNLPTKIIHLWSLS
PHLPYNQSFYSLIYLAQALEQQQPKHKIKIVVGTNSLYDIIGNETLFYEQATVLGALKVI
PQEYTYLDCRQVDLVIPESEQNLITEFTTDTKDKIVAYRGNRRWVQTFEPIPLAKNTQEK
SKLRQEGVYLITGGMGGVGLVLAEYLARTVQAKLILLGRSQLPSQETWDEWLSNHDAEDS
ISQKITKIRDLEALGAEVLTLTADICDRAQMQNAIAVALKRFGKINGVIHAAGVAGGGII
QLKTPEIAESVFAPKVTGTLVLNQVLAGIDLDFLVLCSSLSSVVGGFGQADYSGANAFLD
VFARCNHSNCHTVAINWDAWQEVGMAVNTEIPPEMKQWQADNLKNGLLSAEAVEVFERAL
VSELAQVIVSTQDLATAIEQNNNFLATYTTQKPDSNYQHLSKNYVAPSNKIEKTIAKIWQ
EVIGFEKIGIHDNFFELGGHSLLAVQVTSRLREAFNLDLPLRTLLFEAPTIAQLADAIAD
QITPAADIDEMEQLLTEIENLSPEALKQELARES
>S7VZH7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii (strain ATCC 50853 / GT1)|TrEMBL
MTEAATPQNVTSPADLSKQNVSFRPGVNAVEFVSGYSHAGSVVCSLPSPIFFNKASSSNG
NCESNASTASSSAALGTEASSNVRTGTVLIFDCGSGNTWQHLRQWLSDEGASHIVVVHAC
AEEGADTLGVKTLHPSRVNGGQGCSQTLIKEVKCRPHHPEEVVELFKLLKEGLHFPLVRG
IFYILGEKLDSLLANQTTSSVHDMMKTASGAWSIHHALGQLGMEADLDFFIFFSSISALF
GSISQSISAAVHASLDALAYYRRHLGLAATSIQWAPWADGSSATSPQIVRHWLEKGGVSS
VRNPLAAVSAILKNHTAIGAVVACFHADPTIMHEMGETDQECTFLSSGPAANTRDSTSGN
VKVRTNPVKSRVFQNVSPSTDTCGENHKDELLVILTQLVRREVIEIASCYVFFEGNNLST
DESLVDLGLDSLSAVELRHTLQQRFCVNIEPTFLQANATIDSISALLVTHVATSLTGALP
VLPLSCPGLASAVDDCALVSLALRLPGRCDSLDAFWASLQSDSGYCRPGASEACDQCFMH
RAGSGELPAESQSIGTNLDARKGFCWLSNRDAFDSHFFGISFTEALATDPCHRLLLEATY
EALCKLNTEQQSGTSGTPIAVFATSSSTQMRASLPSYTKPASSQNTQDNNGCLAASFLSY
HLNLTGLAVPIDGSDSASLIALDLGREHLRGTDSVCQAVVVAAGSLLPICSHGWPSACTS
PTIRRFRGRDDHAFPDRETYAVPRGEGIVSVVLQRLSVARENGNSPMAILKGISLIRMGR
GERPIPSQWRTADVKLRRKTIVEALKMSRVEPRTVAVLETDGLTGSQAEDAYTVEAMADI
FGPRHLAESCSPLVIGNASLHIGQAREASGLATLAKLVLMLERGYAPPIPCLRRLHPDVK
RGILPSGFVMFPCKKMDLLAFRQHPDHVYGPNEKRDQKEGRPLIGCVSSLGSDKTSGCFI
VESSPRRHGRTSDTRVSLERAVPLAGTKDACSHNYLHVRSTDGSESEIRGDDRAVWLFCD
DLWGLQSVGRGLYCSDPAFAALLEQAERVLGNRIPQPLSCLLYPSTTAEFQKAEDALAFP
RIAAFVLFSLQWALATCLRHQEGEPTAVMGLGVGEIAAAAVAGILSLEDAVELLELLSSE
TRTCDYRNKPMPGGNVNSGGLFDRGNSGTGGCGVAQDCKSPWVLCGLNKTPTSESAALEF
SVLESRRGSSSRISSETPTSNTTPHNRDVFQERFSRKPRRATCPSPIIRHAWEKVAHGNP
ENDEEAELECPSSQSRRANCPSPAIQHACEETAHGNHANDGEADLLMDVFRFRPEPSEPL
GQVTARIALRNAICLFISTVSGRLATDTLIRAAEYWDPLVPKTQRVHRAVETAVQVAKTA
KLVCIGCSAQDGVHLSVGLPSVHPISPSPLRIFCFTGSSPSPQLLAPCESASGSSPRVAV
VEHHGADSNLGGGAPWWKHLLFRLPQLEGFPSGCSASTRLLADRLVADVPTPDNHMINNP
QTAAVQGAGETLGTLREGSSGEGEDGEKGYRSESVNTQHPVYKVYRRCSEPELHESELSL
LCSDTVCQPSLEKTVELFIGTGLEQQGKLSTVSSSWLVFSDIVAPSPISLYSTLAFQNED
GEQRFCTLNVASQVATVYAEKVKTQVCSIIIECKRGFKPPREIARCHFVKNQTAVGKHEP
AVSSLSRIRWLPATKLPEGWLRTRRPHVWPCKIKVTKAACPLPTRRVDLQEIYWGKRHIL
CRFRMPRNPPRDGVEKSTQLIAILARLVTVSVGVAATCVLHETETSGRYSHSHPGPQVED
DQKTHMDALWVCPYVPFSECWCVIRHRRNGSSIKEGKGRDWETCDVEIFSENGTAVAVVL
GFGIQSHALSMRMMEGRGNDGDSSVSTTVCVA
>A0A2G8XT12|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii COUG|TrEMBL
VAVREDGLYVSRLAPQTEVDVRGAIEFHMPERGAISNLVLRPQAFASRLPPEDGQIELRV
RAVGLNFRDVLNVMGLYPGDPGPPGADCAGVVVAVGDNVEHIEVGDCVFGVAQGCLRTYV
TTDSQLLRRMPESMTFEQAAALPVVATTVEYALHDLAKVKAGDKVLIHAVTGGVGLVAVQ
LCKRVGATVYGTCSGGKKDAFAKSMGVQYVSSSRDAKAFAEDMRTFLGEDGKVDVVLNCL
IDDFIPESLKLLGPYGRFMELGKRGVWSKEKVAAERPDVQYELIAVDEMMEKDPIWFGGM
LVRVRGLVAEQKIQPLPMHVFDLADTGENGGVAAFRFMQRAQHMGKVVLKIPSPVEEASK
NGSIVITGGLGALGMVVAGWLAEEGARHICLLSRREEAPQPGEIPGWDWLRTINCDVQFF
SCDVSKYDSIRSVLRTIQTSVAPITGIIHTAGALADALLDSQTPELMKKVYNGKVQGAWN
LNRALEELGLNEQLKLCVFFSSVTSLFGNFGQANYCSANACLDALAQWRRAKGLCCQSIQ
WGPWIEQGMAAELKQQVERNGMKGISNEVGLRVLHDAIRQQEKATPVIGCQAIKWKLFMH
RYIEQPPFFTNIEMDLQVTSHDSNTVLRNLPPSERRDYIKAQVAAAARQVLGSSSPPPFD
TPLQDVGVDSLGAVEFRNVLSKKLGVKLSATTLFDYPTLNAIIDHLCEVFGESSQKDSLS
TKLGALSENDLVQEGMAIVSMSCRLPGNSTCPDLFWDMLMRCTDCVCDIPLTRWNAEEVY
SEDPDLPGKCYTRRGAFIENAEYFDNSFFGISPSEVKHMDPQQRLLLEVAYEAFAGAGLT
KEKLLGANIGVFVGACNHDWTYLIQEDKISAYTGTGSAGSVIANRVSYCLGLRGPSVPVD
TACSSSLVAADFAFEKLMLRDCTMALVTGVNLMLTPHLFIAFSKARMLSPDCKCKTFDAS
ADGYVRGEGAGAVLMLPYADAKAKQMTIQAVVKGTACNHVGRSASLTAPNGPSQAEVIRM
ALRRAGMKPNDLKFMESHGTGTSLGDPIEVNAVRTVFAPGREKTKPLLIGAVKTNIGHLE
GSSGIAGLIKACLVLSRREIPPNLHFKTLNPHINIEDFPVQFVTDFVSLDSVESTRKKNT
AGVSSFGFGGVNAHVLLEEATRDQNATRKEENRPKICFMFTGQGSQYVGMGRHLYEKEPV
FREAITRCVEIAKEYLPLPLLSVIYPSPDERDKMQEAINETLYSQPAVFVISYALLELWK
SRGVEPDMVMGHSLGEYIAAVCSGVISIQDGLKLVLKRAQIMSRAPSRNGVMVACRATAE
QVEEAIHTLFGDGEKNVALASVNGLKSVIVSGNQQDVQAVLRQLGAASRAKMLRVSHAFH
SPLVKDTVAPFKRVLETVRLSKPRVMFVSTVTGKVARDELQNTNYWAEHITKVVRFCDAV
QACIAQGAKIMVEVGPRPTLSNMGKGCLPQTTADEVQWINSLEPETLSSAVFDSLSALAK
AGSGAMPAVFDRKFFPWTETCHPLLGGKNTRPDGSVVYSALLRDLVKALFLDHVVYGKAL
LPATCLIEMMASATTHMISNHDEEKLVALSQVVFEKPLLVPDDTSLSVLVTVETRGQVRV
ASQVSNSEEEAEDHAVCQVNIVDALPAAPALTEIRARCKTEIEASQLYAQLHNVGLQYGP
RFQTIVKVFKGEDEVLGLLQAQNVTNFETGFMMHPAVLDGALQLSAVLAFEKGSSRAMVP
FGVDTVLLKSCPPEKELWARVVMNRKGVSSASATVHLYDFDGEPIAVLMGVTLRPIEFNT
AADIPRELLWEVEWESAGSYSMPQDGSLATPSGTDDSGAEDVTRTPSPLVTGENENTPSR
EVPSGLPGLSTETPRASKPLSTDETSGAVLNKSVHSVLLVDYAGGHREVVASIRDTCDVE
VEVLSKPGSPELYAQQLRQFAEVVATKTETVPLSTILFLALDEATPAEQLAGGLLETVKV
FAVEKFKKLPCIWVLTSGAQGPTRSVVSPKHAGLWGLMRTVRLELEMQIGKMVRFGCVDL
DKNLEVSVALHFILQKRTEEPFEAEMILRCPSEDSEKDPGTAEVVNRRERSASFVSVGPE
PVVPSTTDASAKSSVTSDRMALTPGALSCFDETANSTEKLIFNAFCPRLHRSPIPVRGAV
ELHMPERGAISNLVLRPQAFASRTAPQSHECEIRVRAIGLNFRDVLNVMGLYPGDPGPPG
ADCAGTVVAVGSGVRHLKVGDSVYGIAQGCLRTYVTTNGNLMRRMPESLTFEQSAALPVV
AATVEYALHDLAKVKAGDKVLIHAVTGGVGLAALQFCKRVGATVYGTCSGGKKAAYAKSL
GVKYLTSSRDASAFAEDMREFLGEEEKIDVVLNSLIDNFIPESVKLLAPGGRFMELGKRG
IWTKAQMAAERPDVYYETIAVDTMMQEDTVWFGGMLDRIRDHVDSGNIPPLPLHVFEMTD
PLAGGVAAFRFMQRAQHIGKVVIRIASDLEVKIPSTTEPAATETAMLAEAGTQGNASIGT
STQQIADRTYLITGGMGGLGLVVAQWLVEEGARHIVLLSRRGEPSDTVKQSSIWEYLTEK
ERTCVSVLPLKCDVSVKDDIVSAVKEIEARGFPPIRGIFHAAGVTADAS
>A0A2P9FFI0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MA5143a|TrEMBL
MTEDKLRTYLRRVTAELQQTRDRLRESQDRWREPLAVIGMACRLPGGADSPEKLWRLVAD
GVDTVGGLPTDRGWDLDDLYDPDPDKPGKTYTREGAFLYEAGDFDPTLFGISPREALAMD
PQQRLLLETSWEAIERARIDPLSLRGSRTGVFVGGLPTGYGALLIDSEEDQGYAITGGTG
SVMSGRVSYSLGLQGPAVTVDTACSSSLVALHLAAQSLRQGDCSMALAAGVGILATPAGF
VIFARQRGLAADGRCKAFADAADGIGWGEGAAVVLLERLSDARRNGHPVLAVVRGSAANQ
DGASNGLSAPNGPAQQRVIRQALASAGLSPSEVDAVEAHGTGTRLGDPIEAQALLATYGQ
DRERPLFLGSLKSNIGHTQAVSGVAGVIKTVLALRQGLLPRTLHVDEPSKEVDWSAGAVE
LLTEARVWPETGRPRRAGVSSFGISGTNVHVVLEQAPEPDDTAESAPTHEDRPHTGPTPW
TLSAATEAALRDQARRLLDHAAAHPDHTAPDIGHSLAVTRAALAHRAVVLADSRDGLLAR
VRALADGDDAPGVVTGTGTKGKAVFVFPGQGSQWVGMAVELWETSPVFAERMGECEEALS
AYVDWSLREVLSDEAALGRVDVVQPVLWAVMVSLAEVWRSYGVEPAAVVGHSQGEIAAAV
VAGGLSLVDGARVVALRSQAILALSGKGGMASVRLPADDVRTMTPLLDGRVEVAAVNGPS
SVVVAGTPEGLDEVIVEAEARGARARRIAVDYASHSAHVEDIREELAEVLAPVVPVSSKV
AFHSCVTGGRFDTAGLDGGYWFCNLRQPVRFEETTRGLLEQGHGLFVEMSPHAVLTGAVQ
ETAEAAERDVAVTGTLRRDDGGLERLLLSLAEAYVHGAPVDWRKCYAGTGARTVDLPTYA
FQHRRYWTDTPAATGAAVGRSVDGWRYRVAWRRITPTAAAPLEGRWLLVAPGGDGGEVAE
ALRTAGAEVEVSGVPATGLDGAYRGVVSLLDSATDALALTQELDAAGARAPLWWLTRGGA
AVATSDDVRGTAAQLWGLGQVVGLEHPDRWGGLVDLPRVWSESTAEVLAALLAGSAGPED
QLAIRGSAVYARRLVRAPLTDRGPVRPWKPRGTVLITGGTGGIAAHLARRLAAEGAEHLL
LLSRRGPEAPGTGALAEELRALGAEVTFAACDVADRDALAAVLADIPGETPLTAVLHTAS
SHSYGPVLDVGQREFADGTAAKVEGARHLDELTAGLDLDAFVLFSSGAAVWGSAGNGTYA
AANAYLDGLAYERRARGLTATSVAWGGWADGGMLSGFPALADQLERMGVRPMRPDSAIDV
LWEAVEQAETTLTVSDMDWERFAPVYALARRRPLIEEIPEAVRALNGERPGADRADGTAA
GQLRGTLAALSEPEQRATLLELVRSRAAAVLGHTDAAEVAAHRPFKDLGFDSLTATELRN
RLNTATGLRLPATLVFDHPTPTALAGRLRDELLGGADAAGTAPAVRRTTDDDPLAVVGMA
CRYPGGVRGPEDLWTLVTEGRDEMGDFPTDRGWEALSLYDPGRDTTLAGQGAFLYDAGDF
DAEFFGISPREALSMDPQQRLLLETSWEAIERTGIDPLSLRGSRTGVFVGGTPQEYGALL
MNSASLAGGYALTSSSGSVMSGRVSYVLGLEGPAVTVDTACSSSLVALHLAGQALRAGEC
DLALAGGVTVMATPGAFAEFANQGGLAADGRCKAFADAADGTGWGEGVGIVVLERLSDAR
ANGHRVLGLVRGSAVNQDGASNGLTAPNGPSQQRVIRAALDGAGLTPSDVDAVEAHGTGT
RLGDPIEAQALLATYGRDRDAERPLWLGSVKSNIGHTQYAAGVAGVIKTIMALRAGTLPR
TLHVDEPTRQVDWSAGAVRLLTGNRPWPETGRPRRAAVSSFGISGTNAHLILEQAPETAP
DEAPGDTPADRPPVPADATSTGHPYETPASGQPDMPVPPGQSAPAVAPAPPVPAVAPAPS
AVVGAPVPSEPRPAAVVPWLVSGHTEAALRAQAARLLAHLDSRTGVAPLDIACSLATTRG
ALTHRAAVVADAPAALLAGLRALADGDPTAPDVVRGTARETPLAVVFPGQGSQRPHMGRD
LYERHPVFAAAFDEICAAFDPLLDRPLRDVVFADDLERRTELDRTAYTQPALFAVETALY
RLLESWGVRPDVLIGHSVGELVAAHVAGVWSLPDACRVVAARSSLMQALPAGGSMLAVEA
DETTVVAVLAAHRDRRIGIAAVNGPTSVVVSGPENAILDVAAEFVGRGHRTRMLTVSHAF
HSPLMEPMLADFAAALADVEFHEPVLPLISNLTGAPAAVGDLRAPGYWVRHVRNTVRFAD
GVRTLLDRGVRTFLEAGPGGALTAMAAATAAEHTEDTVTCLATLRDADRDEADALVTALT
RLAVHGTPVDWRAYYAGSGARTVPLPTYAFQHHRFWLRVLGTGTGGGRDASSIGLTTAGH
PLLGAVTDLPGTGGLLLTGRLDRADQPWLAEHALGGVPVLPGTALVDLALHAGGHVGCDT
LDELVIHAPLPLPERGGVAVRLTVDSADDDGRRPFTLHARPETASDDPWTRHASGALAPA
PAGAPAAGSTVWPPPGARPVPLDDFYATTAAAGLDYGPVFRGLTELWQADGALHCHVTLP
DTAERGADDESAADDGSADGFTVHPALLDAALQPLALGILGADRPDGTAVPAGLPFAWSG
LRAYATGASALRVRLTPTPDGAVTVRATTPDGLPVLDIDALTLRAPSAVPAAPAGTTPRA
EPLYRLDWPTVPPAAEPPSATGGWGLLGLDPRELRPRLAAAIGRDVVPYLDRDALTDTID
TGVPAPATVLQICDPPGRGDTAADAHAVTRQLLDTLRPWLDDQRLTGTRLVLATHGAVTA
APDDPGPLPAAAAVWGLVRAAQSEHPERLVLVDLDDDTASLAALPRALATGEPQLALRHG
IPHVPRLTPLPPPEDPAARQTPPATADAPVAGGPHAEGPAVTPSSGTAPSPEPGASGAPG
PEKVKSAAPPPPMAATPRAPLPGTPFGPDRTVLITGATGALGALVARHLVARHGVRHLLL
AGRRGPAAPGADELAAELAEAGARVTWAACDVADREQLAGLVSGVPVEHPLTAVVHLAGV
VDDGLLGDLTAERLTAVLRPKADAAWQLHELTRGLDLTAFVLFSSAAGVLGSPGQANYAA
ANAFLDALAQHRRSLGLPALSLAWGPWQGVGGMADALTAGERPRPGADGVRPFTAASGLA
ALDRALATPDDALLVPLGLSPGATPVPADRVPAVLRSLVRGSAPRRTLVRGTGRADASAL
AALAPADRGTALVELVCAEAARVLGHSGTDGLTADRAFGELGFDSLTSVELRNRLATATG
LRLQPTLVFDHPTPGDLAAALDRQLTAPAAAPVRAAAPADPTTAVAQAVESLYRHAVTVG
RYDQAGKVLMNSAGLRPAFTSADAVGKAPALVKLGDGGRHPALVGLPSTSVWASDQEFVA
LARPLRGLRDTHSLMMPGFVSDELVAGSVEAAVDHAARTIARTLDGAPFALAGRSSGGSL
AYAVATRLEELGTPAVGVVMLDTYVAGTPQTDYIVHAMESRSLEREAEFGRMTGLRLTAM
ASYFSLFEPWRPRPIATPALLVRACEPIAVDADDLRERPEEWQSVWPVPLDVIDVPGDHH
SMIEEHGGTTARTVHDWLTAHGA
>A0A2P9F876|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MA5143a|TrEMBL
MDARFWEAVEREDVGSLMAALGVDPEERERTADAMEAAVGVLSSWRRRRDEKSAVDRLRY
RVGWKPLANPAPGLPAGTWLVVVPQGTDRAGELLDALAAQGMRTVVLPYDGADRAELTEL
LRKQVDDDLGGVLSLLALDDRSSGASAALSAGAEATLTLVQALGDAGVTAPLWCVTSGAV
GTGPADPVRSPWQALVWGLGRAVPLESPDRWGGLVDLPDVIDERAVRRLLGALSGQDGED
QLAVRPAGVLARRLGRDTSRAVSDWRVRGTVLVTSGTEGLGRHAARWLAGAGAEHLVLTA
APGTGGLPEELGGLGCACTVIETDLTTRDGVADLLARVDALGLTLDAVVHAADLVRTNPV
VGTDTTELVEVLAAKADGVVHLDELLGDRPLDMFVVFSSIAGVWGGGGQGTSGAANAFLD
ALVERRRARGLPSLSVAWGVVEGIGVGADEATVEQLRRRGVSPVAAGLVVTALSQTVTQD
APASVTVADIDWDRFVPAFTGMRGSPLLTDLPEARRIIEAAATDDDGDDAGSEFLRTLLD
APEAEQERILMKLVRSTAATVLGHSGQDAISPHSPFQEMGFDSLAAVGLRNSLGAAVSTR
LPATLTFDYPTPAALVGYLREHLVRAYAQGPSQEDTALAEREAEIRRALAAVPLNALRDA
GILDALLDLAGDGTTEDEPAERDDSDEELIDAMDVDDLLQRALGSTQ
>A0A7D3W2T8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinomadura verrucosospora|TrEMBL
MTGDGLWLTRLTGDPAEPAIRLFAFPNAGAGPNVFTGLARRLPGWIDLWAVALPGREARF
GEPPRTELAPLTAELADALLPHLSRPYALFGDCSGALLAFLVAHRVRELGGPAPVRLVVR
AYPPPDIVNRTPRELLALESAEFWRRLVSQGRIPPEIAAIDDMREVFEPAFRADYRLLAQ
YEYRPMPPLNTAITSLPGPGDPDARRHAAGWAAHGKGDPHHREVGNGGRATDSPAALGAH
LAQTLGDLAP
>A0A7D3VTK2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinomadura verrucosospora|TrEMBL
MTDPEHDHIAVVGIGGRFPGAAGLPEFWANLLDGKDAVRFHTDDDLRAAGVPAGVLARPG
YVRASIEAPDLEYFDAALFGFTPRDADILDPQIRMFLESAHSAIEHAGYDPHKIPETGVF
GTVGMNRYLDMHVLRGYQPTSTTGLATGTLSYPDYTATHLAYRFGFRGPAMSVSAACSSS
ALAVHLACQSLLSGECDAAVAGGAELEVPVHHGYQWDSGGLLSPDGRCRPFDAEAAGTVF
GSGAGAVLLKRYGDAVADHDTIWAVIRASAVNNDGAAKAGFSAPGLAGQIAVVTEALQLA
GVGPGDLSYVEAHATGTVLGDPIEVAALTQAFTRLGLGADAGEPIVLSSIKGNVGHLGHA
SGVVSLIKTCLALRHEQLPATANFAQPNPRLQLDRTPFEVRAETTPWPRVPGRPRRAGLN
SLGIGGTNVHLVIEEAPEPERRAADARPQLLVWSAGSEEGGGRLRAALADAAAGLDATGV
HDLAATLQEGRTVHAERAAVVAAPGGAAAALRDAPAIRRTGGQPRDVAFLFPGQGAQHVG
MARALHAARPDFAAHVDDCLDRFADLPGDLAVPDLREVWAAEDDGAGDRLADTRYAQPLL
FSIGFGLARLWADLGVRPAAVLGHSLGELTAAAVAGVLDLDDAVTVVAARAAAMGSMPPG
AMLSVRLPADELRPRLRDGVAVAVVNDPAATTLAGPSDAVLALAGELSAEGVAVRRLHTS
HAFHCDLMAAAVDPFLTVLRGVKLREPRVRLISAAAGGPVTGEATDPRFWAEQLVRPVRF
DRGLSALLDEAMLALELGPGRTLTALAQGTDQVRSGASAARPCLAPPVRNDDLDDETAFL
EAAGAVWVEGHPLDWQRLRLGEPAHRIPVPGYPYERRRHWVDPHPPSDAGTAELTEPAEL
AGTTLMSHDAPAEQSVVPDAGDETAFGDPVWVRLPSLAPPPRRVRTALVLAPAEEGAARK
VTLALQRGGCRVTLARPGDAPAADGTEWRWRPDDPDDLERLLTAGTAHGDGPDLVVHALA
LRPWPAPTLASIDEQLRESVQSVRTCAQVLARRRPGTELIVLTDGAADVSGAETPHPAKA
SLAALVRSLRDETGDVPCRLVDTTAAACDVAALAADLAAEPDDPVVALRGARRWARTEAA
VTPGGPSASRGPAVREGGVYILTGGCGGLGLAVARALGETGAGPHLVLTTRRDPAALPAS
DLSAIRATGATVEVRRCDVTDLDGTRALFDAVRAERGAVHGVVHLAGLPGEMVLLRRSAE
ATAAVLAPKAHGTLVLAEVLAGQGAALDFVVGFSSRAALTGLVGGADYAAANAFMDAAFV
GLARAGLPATTVNWPAWRDVGMASDPGPVTTPAPAPAGGGTAPDARRWETTVDVASWPIL
DEHRLSGTPILPATAHLDLVIRAFRESVAGEAGPVRLDEVVLHDVLDGSQTRRWSCEFAP
RGDGWEFTARSHPQAESAHPSAMVHVTGRVRAAEAAPPPDGALARLAGEMTVPAAPEPDP
DGFDLGPRWDVVESTTLRGDDDGERLLRLRLPEAFRGELAGHAVHPTLLDAATTEVRRPA
SDGLALPFRCGSLTVYEPLPARVVSHIRRRPSANGVIVADVDVYAEDGRRVAAIGGFTMR
RVQGGALAPARRPQPPARTADGLDPRTGGELFLTLLSSPRLEQVAVRPYESGRPVALARS
DGHTPLRPSAQAPVVPKPGADARPDTARPATPITPPTANVPAPENAAGPAPTRSAPTSGN
PPGADTRDRLAALWRAVLGDTRTGGDGDFFKLGGNSLTAVELMNAINAEFGLELSVIALF
DYPRLDDLAGFIESTAKEPA
>A0A7D4A2T3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinomadura verrucosospora|TrEMBL
MADDIRENDVAIVGMACRFPGANDVREYWDNLVKGVEAIRFLTDDELRAAGVPERFVNDP
NYVKACPMIDDMDGFDAAFFGYTARDAELRDPQGRLFLETCHSALEDAGYDVGRYSGTVG
VFGGAGEYRYGSDNVRRNGAAVDAAGGMSVATATEPDYLATTVSYRLGLQGPSFTVQTAC
STALVAIHLGCQSLQMGECDMALVGAVDVRLPYGRGHWRVDGGIGSADGHVRAFDAAASG
TIFGSGVGVLAVKRLADARADGDHVYAVIRGSAINNDGAARAGYTAPGVEGQTRLIVEAL
AVAQVPPETIGYVEAHGTGTLVGDPIEVTALSDAFRAAGATAAQYCALGSVKTNVGHLGA
AAGVAGIIKACLAVRHGVIPPTLHFQEPNPAIDFESSPFYVNTEPVPWTGPRRAGVSSFG
IGGTNAHIVLEEPPEHVRVPDERSSPQVIALSARTGGALAAMAARLGEHLGEPDPPPLAD
VAWTLQHGRREFPYRRTVVAATVQDAAAALRDLAGAAASTRPVPVDGRGVALLFPGQGAQ
YPGMGEGLYRTQKAFRTVIDDCAEVLEPLIGADLRDLLYGGAPDEALARTRLAQPALFAV
EYAVARLFASWGVVPDALLGHSIGEYTAACLAGVMSFEDALAVVAARGELMQGMPPGSMA
AVPLPEHLVVPMLLGGVEVAAVNGPAATVVAGPDAAVDAFEKRLAPWGVRCGRLVTSHAF
HSGMMDAIVEPFRERVASVRLNEPRIPFLSNVTGTWITAEQATDPGYWAAHLRSAVRFAD
CVRALADGADRVLLEAGPGRTLTGAARQCLPGARTVLATSMRHPLGEGDDEVLALEALGR
LWSAGVPVGWDGAASGDRRRVPLPVYPFERRRYWLDPDPAGTAGQDAEEHDEGARPVERA
VYAPVWTERPIGTEIPAVPDGSRWLVLTPGTGPVEDLADRLEAEGARVVRVTAGPGFAET
GADRFAVRPAERDDYEALLGALGDGAFPTHVVHGWTATAAEPDPLAPEAVERACDLGFYS
LLLLAQALEDRLPDEPVRIVAVSTNMQDVSGEGANEPGKATLLGPAILMNRELRHVGCRS
VDLAAPARQPADVVTGQLLRECLRDDDADRQVAWRGLKRWAWSYTGVPVEVPEEKPAVLR
EGGTYLITGGLGGIGLTTARELARTARANLVLLGRTAPPDRDAWPALLADEGTDEATRRL
LGELAEIEELGGTVLARACDVTDEDALAAAVAEAVERFGRVDGVFHSAGVAGGGLLAVRD
REAARRVLAPKVAGTLALHRVLGDDVDFVVLYSSITSVVGDFGQVDYCAANNFLDSYARR
RAASGARVLSVSWGAWRDVGMAVDAARITPNVFREMRGGKWSEPAEHPLLGRRLHDLSDD
VVFSTVLGPESHWMLTDHRVGAIPLMPGSGCLEMIRAAAVTALGAAADEHVEMTDVVFLG
PIEVRTDQEMRITLRPAQDGFHDASFTVAPADTDDPAAWTERVRARVRTVPATPAPVHDV
EAVRAECADHRFEPTPDFRSRGIVDFGPHWYSVERVDIGARRQLGTVALPEEFRAECGQY
VLHPGLFDDAVSNARVIEGIRKGNKYLPLSYRRILVRAPLPPRFHVDVRELDDAEGEIVA
ADIRVMAPDGTELAEIEQYALRRVDPAAFAEGAGGDEGAPAEPGPAGAPAPAAAPDRADW
MITPATGMDALRALLGAWGAAPHLVVCPEGLEANLRRVESLTGDVLERELGDGAVVATTA
AQGERLLDTPYAAPETPLQQRIAALWSDAFGIREIGLDDDFAELGGNSLMAVQLAWRVRQ
HFDVEVTVARLFRRPTVRALAELVENEQGAR
>G8SKU0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinoplanes sp. (strain ATCC 31044 / CBS 674.73 / SE50/110)|TrEMBL
MRDSRGTGSVGDHLAQRRAGLAGSLRDLPVPEQVRRLRSLVTGQLLPILRTIRPAEEIVV
AGATPFREQGLDSLGLVDLHARLNAATGLALPVTVGFDHPTPDALAAYLRAELLGLAESG
AEVVAAARASDEPIAIVGIGCHFPGGADSPEQLWRLVADEEHVHMPFPADRGWDLDNLFD
DDPERAGTTYVRHGAFLTGAAGFDAAFFGIGPREAAAMDPQQRLVLETTWEALERAGIDP
GTLRGGRTGVFIGAEPQEYAVRLHEAPDGLDAYLLTGNTTSVLSGRVAYLLGLEGPALTV
DTACSGALVALHLAAESLRRGESALAVAGGVAVIGAPGVFTAFSRQRGLAPDGIAKPFAA
AADGTSFAEGAGLFVLERLDDARRNGHPVLAVLAGTAINNDGASNGLTAPSGAAQRQVIR
QALANAGLTADQVDAVDAHGTGTTLGDPIEARALIAAYGPGRDADHPLWLGSVKSNIGHT
QAAGGAAALIKMIMAMRHDLLPRTLHVDAPTPNVDWSAGTVRLLTEATPWPRRDRPRRAG
VSGFGISGTNAHVIIEEPAAVPEPERPAAPVPPVLPIALAARGDAARRAQAERLLTVLDD
DAAPDLTDLARALLTGRAALPQRAVVVAADAGEARRGLRAIAAGEPDPAVVTGVARDARL
AYLFTGQGAQRFGAGRELYAAYPVFAAALQDAVAHLDLHLAVPLGEVLFGASADLLDRTE
YAQPALFAIGTALFRLLESWGLRPDFLAGHSIGELTAAHLAGVLSLADAAALVAARGRLM
QQLPAGGAMVAVQATEDEAGPLRDADLDLAAINGPEQIVLSGTRDAAEAAAARFAALGRR
TRFLDVSHAFHSPLMEPMLEEFGRLAAVLDYRPPAIPVISGVTGRPATTEELTDPGYWVR
HVRAAVRFHDSLTWLLDENVGTFLELGPDPVLSALGRAAVTDRANAPVFAGTLRRDRDEA
REVATAAATAHVRGARLDGTGLFGAPATAVPLPTYPFQHQHFWLHGAQTGRVDAPGLGQI
AARHPFLGAVVPMAGAGATVLTGRLALAEHPWLADHVVAGANLLPGTAFLELALRAAEQV
GCAAVEELTLAAPLVLPATGGVALQVVAGAPDATGRRTVELHSRAGGEHDEWTLHATGRL
GDAPAAGDGLGVWPPAGATAVDVGGFYADLAGQGYGYGPAFQGLRGVWRRGDEVFAEVTL
PEPVRAGAAGFGLHPALLDAVLQATDHATPPADPGVVRVPFAWTGVTLSNPGAAAVRVRI
TATGPDTVALTLADAGGVPVATIESYAVRPLTALPAARAGALYRVGWRPLPVPAGLPAAA
PVLAGVTSAPGDAPTAARATTAAALGRLRDWLADDRTAASLLVVTTRGAQAVDGPADPVQ
APVWGLVRAAQAEHPGRFLLADLDDDPRSADALAAAVAAAVAAGEPEIALRGGETLVPRL
AAVPAAVPGSATSYDTGTVLITGGTGGAGARVAVHLAAHRGARRLLLAGRRGPDTPGIDA
LVAELAALGAETTVAACDVTDRAALAALLDTIPAEHPLTAVVHAAGVLDDATITGLTPER
LDAVFAVKADAAWHLHELTAGRDLTAFVLFSSTATLLDAPGQGNYAAANHFLDALAGQRH
AAGLPATALAWGLWSDAGGMGAGLDEAALRRIERSGLAPLTAAASLALLDRAVDGEDPAV
VPVRLDATAAGRRPDGVPALLRDLVRTPAARRVAPAGAARPLAAELAALDPAARAEALLT
LVRAQAAAVLGHDDAGQVDEDRAFSEIGFDSLAAVELRNRLADLTGLRLPATLTFDYPTS
VALAGHLATALGEAAGAPVPAPSAGPAPTDEPIAIIGMACRYPGDVNSPEQLWDLVLRGG
DAISTFPEDRGWDPDTYDPAPGVPGRSYSNEGGFLRDAAEFDAGFFGISPREAQAMDPQQ
RLLLEVAWETFERSGVDPASVRGTGTGVYAGVMYHDWGLRLGTLPEELAAYHGNGSLASI
ATGRIAYTFGLEGPAVTVDTACSSSLVAIHLAAQALRRGEIGLALAGGVTVMSTPDTFVD
MSRQGGLSSDGRCRSFGAGADGVGWGEGAGLLLLERLSDARRNGHRVLALVRGSAINQDG
ASNGMTAPNGPSQQRVIRQALGAAGLTTADVDVIEGHGTGTRLGDPIEAEALLATYGRDR
PDDRPVRLGSVKSNIGHAQAAAGVAGVIKMVLAMRHELLPRTLHVDEASPQVAWDSGAVE
LLTSEQAWPRSARPRRAGVSSFGISGTNAHLILEEPPAAGPVPPVGDLPLPLLLSGRSAA
AVREQAALLDTYLRERPDSDLTAAALALATTRAALPFRASAADPRDLAAPVVTEAGPGRT
AFVFSGQGAQRLGMGRGLYAAFPVFAAAFDAALTDPGLRGVMWGDDVEALNATGVAQPAL
FAFEVALFRLVESWGVRADFVAGHSVGELAAAHVAGVLSLDDARRLVAARAGLMQALPPG
GVMVAVQAAESVVRPLLVEGADVAAVNAAGSVVLSGEPAAVDVVLAGLPGVKTSRLRVSH
AFHSSLMDPMLAEFAEVAAGIDHGVARIPVVSTLTGAVADFDADHWVRQVRQAVRFADAV
QHLEAAGVTRFVEIGPDAALTPLIDATGIATQRRDRDEVTELLAATGRAWTHGVRVDWTA
VRPAPVAALPHDLPTYAFQRRRYWLDVTPAGDVGAAGLDPVEHPMLAAAVVSAADGGLVL
TGRLSAAGPGWLADHDVLGRVLLPGTGFVELALRAADQVGGAGVEELTIEAPLTLPARGG
VAVQVVVGPASGAGIRTVAVHSRAEAGAPWQRHATGTLTAVAAEPDFDLMAWPPAGAAPI
EVTGAYERLRDRGYAYGPAFRGLRAAWRHGDEVYAEVALPESAHADGRRFGLHPALLDAA
MHADLLGDDPDAPTLMPFAWTGVTLHATGATALRVRIRRVRGDEVSAMWIADDTGRPVAT
VGTLVSRPVSAAQLRGSTAAGDAMFRIGWQARPVTPDGRVLPEAGAAAPGPLVALTLRAS
GADVPATVRAVTGDLLDRLRAWLDDDATAGSRLVVVTDRAAAVRDGDDADPRTAPVWGLV
RAAQAEHPGRLQLIDTDGTPESDAVLAAAAATGEPELAVRAGQVLIPRFEPAPGGDREIP
WPTGGTVLVTGGTGGLGALLARHLVTEHGVRHLLLTSRRGPDAPGAAALADELRAAGAEV
TVVAGDVARRDDVAAMIAAVPADRPLRAVLHAAGAVAGGTLAALTGEHLDTVLAPKVDGA
WHLHDLTRDRQLDAFVLISSAGGSVLAAGQGDYAAANVFLDALAAHRRAAGLPATSLAYG
MWAVDTGLGGALGRADLERMRRLGLPALEPAAALELFDAAVRQDSPAVLLTRVDRTALGA
RTDELPALLRRLAPPARRRAPAATEPTAFTDRLAGLAEADLLRTLIDLVRGQVATVLGHE
GAAAVAPDRAFRELGFDSLAAVELRNALSATTGLRLAATLVFDHPTPRAVATELATMIGG
RPAAEPAAPERPATVRPADDPIAIVGISCRFPGGVRSAEDLWRLVAAGEDAIGPFPADRG
WAGDSIYDPEPGVPGKTYTRAGGFLYDAAYFDPEFFGIMPREALAMDPQQRLLLEGAWEA
FERAGIDPAGMRGSRTGVYAGVMYHDYASRLPEIPAELTGYVGNGSAASIASGRVAYTLG
LEGPAVTVDTACSSSLVAIHLAAQALRNGEVAMALAGGVTVMSAPEIFVEFSEQRGLAAD
GRCKAFAAAADGTAWAEGLGMLLLERLSDARRNDHPVLAVIRGSAINQDGASNGLTAPNG
PSQQRVIRAALDAAGLAPAEVDAVEGHGTGTRLGDPIEAQALLATYGRDRTDEDPLWLGS
VKSNIGHAQAAAGVSGLIKMVMALRHEQLPRTLHVDQPSPQVDWTAGAVRLLTEPVAWQR
GGRPRRAGISSFGLSGTNAHLILEEAPAEPVTTPVRVPGPVLLPISARTAAALPDQAGAL
RAHLAEQPDADLGDVAYSLATGRAALGHRAVVLAADRDAALAGLAEVEPVTAGDGLTAFV
FSGQGAQRLGMGRGLYAAFPVFAAAFDAALTDPGLRGVMWGDDVEALNATGVAQPALFAF
EVALFRLVESWGVRADFVAGHSVGELAAAHVAGVLSLDDARRLVAARAGLMQALPPGGAM
VALPVPLDRVEPLLTAGVDIAAVNGPASVVISGAEDEVLTIAAAFPSARRLRVSHAFHSS
LMDPMLADFAEVAAGIDHGAARIPVVSTLTGAVADFDADHWVRQVRQAVRFADAVQHLEA
AGVTRFVEIGPDAALTPLIDATGIATQRRDRDEVTELLAATGRAWTHGVPVDWAALTPAG
RTVDLPTYAFQRRRYWLEAPPSRPGDPAGLGQHDAAHPMLGAVVVAAESGTVTLTGRLSV
PTHPWIGDHSVLGTVLLAGTSYVELALRAAAEVGCDVVEELTIEAMMTLPDQGGAAVQVA
VGAPDAAGRRGFTIHSRAEDAPAEVGWTRHVSGFLAPGAPVATTASFGLTAWPPPGAEPV
DISDVYDYLTGQGYHYGPMFRGLRAVWRQGREVFAEVALPDEARSEAGRFGLHPSLLDAA
LSATDFLDGRRPQDVGGTQLPFAWTGVALHAGGANRLRVRINWVGSDAGAGSEAVRLQLA
DPAGRPVATVESLVVRPVTPDRVAAAATAASGARRLDTVFRVNWTHLPLGGANTAVAGRW
AVLGEDVFGLGPTVPVFADLTALRAAGRPAPEVVLTGTAPAGGDVPGATRDRFDEMLRLC
QEWSADQRFAQSRLMVVTTGAVAVDDEAAELTQAPVWGLVRAAEQENRDRFVLVDVDDPG
RAAPLLAPIAAAGEPEAAVRGSQVRVPRLTRATAPATGHPAPWDPAGTVLITGGTSGLGA
VLARHLVTAHGVRYLLLLSRRGADTPEAKALSADLTLLGAEVTVAACDVADREALAGVLA
AVPADRPLRAVVHAAGVMDNAMLGSLTADRAGRVLRPKVDGSWNLHELTGDLDTFLLFSS
TSGLLIGAGQASYAAANRFADALATHRRAAGLPATALAFGLWTTPTGLGGGGFDAAAEEQ
RMARLGMPAFDTADGLAMIDEALALGEASLVTMRVDTGALAAAPAAAVPPLLRELAGTPV
TRTPQSSVTAVAPAPEASLEQRLSALTGAERADLLLDLVVAHVAQVRHDEPDAVDRTRGF
TELGLDSLAAIELRNRLSTAIGMRLPATLMFDYPNPTALAGFLLEELEPTLAPPPAAPDP
DAERLQAALAALTPARLREAGLFDRLLALAAGDTGPSIEEMDVADLVAAAMATTDNGGE
>A0A0D2JVM1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Monoraphidium neglectum|TrEMBL
MAATAAHLALGGGGSGSFETALSGLTIQAPLLLPHRGAASHTPQLICELSPADGGLLIRS
APSDDASAASSRPTTHVVGSVRLVAAPPARPLDRAGALAARAARLLASARPPLAPPPAAA
GPALGWVQGAASKSEDAGADLGELDSFLQLGQVFILDRLGSSASYVPAAVDAAVLSGPDG
PSAGSGAERPSAALAAPRAHGGAGAGEAVSDFRLLSGRGDGAICWIQGLRAKPMSLRAPA
VRAAGTAAVASEIAASEQSDLIYEVEWLAEAPVAEEECDKDAAAAATRVWLPGGVPAPKA
IAAALVAAKGALLPGAGGAPPRAAALRLNGRPTAAAAGAGAILRTLALEIPDSHMEVAES
DPLAAAPEHWLPHPAALSATAAAAPLKASLHRDAFGARRSGAVGLVPRLLPSAAARARGP
YQLQPRPRGALESLVPVAADVVPRPGQAVVAVKAVGINFRDVLNVLGMYPGDPGLPGSDF
AGVVASGPDAGAAVFGLTTGALASHALCSPLAMAPMPPNLGFEAAAAAPTVLTTVNAALR
QLAGLRAGESLLVHGVAGGVGLAALQAAVAAGARALGTAGGPAKRALARSLGARAVVGSR
DTGFTCDLAVAAGGADVVLNSLTSPGMVGGALALLRIGGRLVEIGKRDVWTGAAVAAQRP
DVAYSLLAVDFLPETVLQKLLRQLSADLAAGRMAPLRGVVHGMAAAQAALRQMSQARHVG
KVVVSTRTAGPGVPATTGAADALAAGGAGSVLVTGGTGALGGLVAAWLAGAGAARHLLLT
SRAGCLAAGGDGGAPLPLLDPSSPLFAAAVTITACDAASAADVAALPATLAARGAPPLAG
VMHAGGVLADASLANQTLPGVRRAAAPKAGALGPLRRSLLAAAPVTQVVLFSSVASLLGS
AGQANYAAANAALDAAAAAMGGAGLPVRSVQFGAWAGAGMAAATAAKVEAMGIGALSAKE
GLAVLEGAMSAQLGARLGFRAPPVLAASPFNWRRLLAGRAHTPQLLLEHAPSAPGPDAPA
SAAAATAGAASAGAAGRLASMAAGQRRELVRKQVEGVVSDVLGAAVAPDAPLMAAGLDSL
GAVELRSSLEARLGLRLPATLVFDYPSQAALVEALDGMVAAEAGQAASEAAASSPAATGA
GLQPRAAALQGRGMIAVSAAAARAPRGAAGCGDGCGGAGAGGRQPGALGDATAATPLERW
DVEMSLTQERPARFGAFIDGAQDFDCAPFGLSDKEAVMVDPQQRLLLEAGAQLLAAAPEA
AKDAVGGAAGGGWLAHVGVFVGISTPDYSDLKKAATPIGVYSATGSAISVAAGRLSYTFG
MRGPCAAVDTACSSSLVATHFAALSMGEGGCVSALVAGVKLILTPSLSAMFTRAGMLAPD
GRCKTLDAAADGYVRGESLAALLLHHLPGGTDAAVPGGAAPSWALAVLAGSAVNQDGRSS
GLTAPNGPAQQEVIRQALAAAGLMPTEVDLLQLHGTGTSLGDPIEVGAAATALSNGRGAR
TPAGGADAADAPPPLTLASDKSGVGHTEPAAGLTGVLHLLRGLAGRAAQPVLHLRALNPH
LASSLAPGAFAALSMPRQARGAPGHGGEGSVIGGVSSFAFQGSNAHILLRVDRPAAAAAA
AGAGAAAQLAQPWRRRYAYVLPPAHALLQSASPQDAAAAGRCSFVARLAHPLLSFLSDHV
VGSRAVAPGAALLEAALAAGCCLLSSGADDGGNLVGLSKVVISAPLVLPAGGELGGAELR
VHVHPATGAVSVCSRGAAAAGGGVAEHARGSFVRLSARGSDDGDGEAWSNAVDSEFDRAA
ARGLEPLDTRRLYADLAAVGLRYGPAFRLLRAAKAGAGAAAARLGRPAVADHGAWHVHPA
ALDSALQLGAAVRGAASEAEAAAGSSRTFVPASLELFALAPAGSARPPRAWDADGATAVA
SAPAGVARSMRAASGGAAALVRDLRLSLGGRLLCSVEGLESRAVSAQALLGGAAAGTAAP
KGPRAAASAEDLAENEEILYQISWVADAPARHDDVDAAAALATAAKTAVVPAAAGARGAA
ASAADALQLLQGLVAAGAASSNTPPAGVQLRTRAVGPAGAPPGPAHAAVIGLREQAVWGM
LRTAAQEAAGLAVTANHADPLGLALHSPASGFRLLAGPQQLRQFDGYGAADAGDTAYAPR
MLRAEAGAAPPPHQLVPRPRGALGNLVPVAVNAESALRPGEVLLAVKAVGINFRDVLNVL
GMYPGDPGNPGGDCAGVVLASNAAAGARPGDAVFGLATGSLGSHVHASALTLVPVPQNVG
FEAAATMPTVFITVDAALNQVAALRPSERVLLPAAAGGVGLAGIQLVQALGARPLATAGS
PAKRALLRSLGVDAVSSSRGLGCFEECALFGGADVVLNSLTSPGMVGGALALLRRGGRLV
EIGKRDVWSGTAVAAQRPDVAYSLLAVDFMPEAGLHAAMARLSARLAAGVVRPLPSAVHD
LRNAAAALRQLSQARHVGKVVVRASGAVPATSGFGGGRGRGSPPFSRGERGCNGAVIVLG
GTGTLGSLMVRWLAESGVGWIPAASRSGRLSGPLAEQLLGSSRASAAQGAAVSVVACDGG
AAADAAALEASLGGREVLGVLHGGGVLADATFANQTASGVRKVFGPKVQALELLQRLLRR
HPVATTVLFSSVASLLGSPGQANYSAANAALDAAAAALQAGGVTALSVQWGAWAGAGMAA
NDPQTAARVERMGMALVSPKAGLAALEGALTASAASTKPVVAATPIKWRRFLARLPHPPA
LFEAFAAAPAAAAAAGPSAATAPALGSIAARVAAAVASVVGRELGPDAPLMESGLDSLGA
VELRNALSDMFEVDLPPTLTFDHPTPAAVAGFIATTKYPGGIPSDSASAAPTDARDPPPL
QPAAGPTASMAAAAPRRGPLLLTALSVRFPGAAGAGGLYAAMRDGSELHSAAPYPRWDVD
AVYHPAAPDVSMTSSPRVSTRWGAFLPDVHCFDAAAFGLSAAEAAMMDPQQRLLLEQVAD
AAVGSGRPLQELAGSRGGVFVGCIWLEHGELLARYGAPGSSMAVTGNGLAFMAYGVTKQR
SQVVVRVGDEEQRTTIGLGLDPTWEETFEFAVADEATTRCFVKFLMGAEGEEKQIGDECE
YLLNVLIVNKPTYKGLIVPGGKVDMMFTAKGFGKEDVVEDDSALLDMLDGGEMMMSDDEE
>I9NKW1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Pelosinus fermentans JBW45|TrEMBL
MMHTETTAKSQIIKKALIEIQRLKQELNAQQNVHCEPVAVIGMACRFPGGITDSEKFWEI
MVEMKDMICSIPDTRWKKYHGKNILDNPYIRKAGFLSEDIEAFDHRLFRLSPKEAERMDP
QQRIFLKVCWEALENSGYAPDKLKGSKTGVYAGVTLPDYINELYLDKKINASLEPGDVTG
SGFSFLSGRVSYFFGFQGPGITVDTACSSSLVSVDQACKGLMTGDCDMAIAGGVNLLYSP
ETTELLSTLNILSPDCVIRSFDAKANGTVRGEGCGVVVLKKLSAAVRDGDHIHAVIRGSG
VNQDGLSSGLTAPYGPAQEKLITDVWQRCKLDPRDIGYLEAHGTGTELGDPIEISALGNV
LAKDRITPLYVGTVKTNIGHLEAAAGIAGLIKAVLAVENGKIPGNLHFETPSPHINWQNI
HVEVPRKTLLWENSMDKPRIAGVNSFGLSGTNAHVVVEQYCNKSPRERGNSLLCDKEKVL
PFKFSSITERGLRDQLEGFLTYLEKIAKRADISFPDLSYSQNIAKADLKERIVVWAKSAE
ELKTNIKQALAGRTNLDVSRKNTDKKVIFLFTGQGSQYPAMFADFYRENRIFRSCLDQCN
TYYKENTGKDLIEIIFSSGSFLHETRYTQPALFAVEYSLAQMWLEYGVEPAFMMGHSVGE
YTAACLAGVFDLADAVKLITARGELMYSLPQNGKMAAVLTGKKIVQNIMKDKKSVSIAAA
NTPEQTVISGDEKEVKDVCAALENDGIKTVPLQVSHAFHSPLMEPIVARFEAVARQVKYF
VPSKVLISNVTGSQIGAGIASWEYWSRHIPAEVRFYESVKSIENPEEYVFLEIGPFPVLT
SMVECICGDKADCIASNYPDVKTADQIEKSVFHLYNRGVNIEWKKYYAEAGCKKVAIPNY
RFSEKHFGLAGLNGEHWFLTQHDQVDSPGGLDLSVFPGDPLSGQAFSNPDEVKKYIRAAL
IRELKTAEDELLDDQNLLLYGLNSIVTTRLVASWKSDLAVPLNPGIFLSNCTINKWTEII
CEKMRNQETGFEEKIPFHSYPDKSYEPFPLNEVQYAYWAGRNAELEWGGVGCYASFEIDA
NELDPARFEQALHALLQRHEMLRNIISVDGTQQIMPEIKPPLTVYHREAVPDLQTHLEVV
RGEISTQVIPLGTPMFDIRLTEMNEGQWRIHFGIDFMIADALSLFIFWKDLACLYSGGRL
PVLEVSYKDYLSYTFERKKGRQYELDKKYWLDRAEGFPAAPEFPVNLSGGQAVKRKFVRR
KKLLDRETWLSFVQAAAGQNLTPSAALLSLYVEILSAWGAGSHFALMLTVFDREDVHPQI
NQIIGDFTQLMLVEIRRDNIAAALNAAAIQSQMQADIEHSNYSAIDFVKELNKRDDAQER
MYPVVFTSALGMENLNDNAGLGGFLDNMGWSVSSTPQVWLDHQVYNEKGGVTLSWDALDD
VFQPDVVNSMFEKYVELVMRAARGQNFWSETVVDLRTERQRQTHENANSTVREFKDTLLH
EIIRHRAFTDADQTAVVFDNQQYSYQQLIARANQVSQLLQEQGVKKGDRVALQMGKSFEQ
IAVVLGIVQAGAAYVPLSCDQPASRTLDILRKAEITILFVDHALSLGEEAVKQLISLELE
GKDGVWHEVEISPSDLAYIIYTSGSTGTPKGVCISHHAAMNTIIDVNSRLGVTAADRILG
VSALSFDLSVYDTFGVLTAGGALILPTEAERMDPKCWRRLALEHHITLWNSVPALMDIYA
DFLGGGNSGKDTCIRQIILSGDWIPLGLFDKIKQALPNAQLTAMGGATEASIWSNYYHVT
GIEPEWRSVPYGYPLANQSFHILDEFGRPCPDWVKGKLHIAGQGLANGYLNEPGLTNKAF
FQHAALKQRLYDTGDYGRYMQNGVIEFLGRQDNQFKINGYRIEAGEIQSAFGKCGITGDP
VILPVGDRMESKKLIAYVKGDPASFSESDLKNSLKAYLPSYFIPERIIAVKDFPMTFNGK
VDRQKLLENLGDLTKQATSSAYYGIAEYHPVLQTVREILNLPELKPADNFGDMGVSSVDI
IRLANHLETVYADRPSVGEMVRYRSVSDLIDFYRQKNIGLADKNAKQLVPDARFCMFSQE
QIKYLSKIEPITNPDEREYFRKAISAQRSELLANERIPLEFDELSLKKDHCFWHKSDQEF
LPAQIDQISFKQFLALCLQETAHKDKKFNYGSAGGIYPVQIYLSVFKNGIEGIAEGSYYL
DVREHSLVQLHRHEMLSPGSPASGCGGLKNAAFLIHFVGDLNVVYPIHERNSLKLCFIET
GLICQLLETHAGLFDIGCRQVGAYEFEKKHVLFDLTAQHYYLHSMAAGKIDFRREKAKMI
ADLSASATDNFREMEMLTEKCRAQEIHLRLEGDRLKFKAPAGTMTQEIQAELKANKEGLI
RYLRETPGQTGSDFSLQVNRAFRLTPIQLAYVLGRSPDYQLGNTSAHYYAEFECSSINPV
QLENAVNEVIRKHEMLRTVIYDNGTQQVLQGNPRFKIPVHHIDDKRKLEEIRSEWSHHRY
ELGKWPMFHVQISQLDDNISRLHFSFDCLIVDGWSAEMMFREIFRAYYGKAVTQPDFTFR
EYINQEENWLKAKSYHKEAGLYWEERLHNIPPAPELPLKKNFDEIVQPRFRRLQFVLSSE
DSRTLGERIKKYRFTPSAVICTAYMKVLSCWSSRKDITLNLTLFNRLPLNKDVPRILGDF
TNITLIAFFYNSGSSFVQETGDIQNQLWKAVEYRTHNGLDLLRRLAKDSPGKAVMPVVFT
SLLFGESSETAEQIFLPDMKEVYAISQTPQVAIDHQAYERNGSLSLIWDFVEEAFEDSVI
EGMFAAYRSLIERLIAEEDWNKVFTVRSSDV
>A0A2N9BJJ1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces chartreusis NRRL 3882|TrEMBL
MTDERKVVDYLRRVTADLHETRRRLSEVESNMREPIAIVGMACRYPGGVSSPEELWRLVA
DGADATSEFPTDRGWPEDLYDPDPDVSGKSYVRRGGFLDDVAGFDAEFFGISPREALAMD
PQQRLLLEVSWEVLERAGLKAEDLRGSRTGVFIGASTSAYVPELDQVPDTVEGYTLTGNH
ASVLSGRVSYFLGLEGPSVTVDTACSSSLVALHLAVQALRQGECSLALAGGVTVITGPTA
FIEFSRQRGLAEDGRCKPFSAAADGTSWAEGVGVLAVERLSDARRNGHRVLGVVRGSAVN
QDGASSGLTVPNGPSQQRVIKAALENAGLQPQDVDAVEAHGTGTKLGDPIEAQALIAMYG
KDRSQDSPLWLGSVKSNIGHAQASAGVAGVIKMVTALRNEALPPSLHAGDPTPMVDWSAG
SVSLLSEGVAWPRGERVRRAGVSSFGVSGTNAHVIVEEAPAAEESAVEPVVDGGSRLVPW
VVSGAGPGGLRGQVERLVSFLDGRPGVDVGAVAGALAGRAGLRHRLAVVGESVGELVAGL
ESVVGEGGVVAREGVRVGLLFAGQGAQWAGMGRELYEGSSLFAGVVDELCGVLDGLVGGS
VREVMFGLGGVEGLLDQTVWAQAALFVLEVGLFRLVESWGVVPDVVVGHSVGEIAAAHVA
GVLSVEDACVLVAARGRLMQGLPVGGAMVSVAAGVEVVEPLVVAAGAGVAVAAVNGPAST
VVSGDADAVGVVVAACEERGFRTRRLRVSHAFHSARMDPMLDEFRSVVEGLGFGEARFGV
VSTLLGRVAGPGELGRPEYWVRQVREPVLFAAAVGEAVRAGVGAFVEVGPGGGLTAMARE
CVGDGEVVLVPLLRKGRGECASVLGAAGRLWEQGVEFDWRAILPPVPAVELPTYAFDHTP
YWLERNKNGVDVSGVGLREVGHGLVSVAVEVAAGDSVVLSGRLSAASHGWLTDHSVGERM
VFPGSGFVELVVRAADEVGCPRIDELTLREPLLVPPGLAVDLQVVVDAADGDQRRGVAVY
ARPVDSETWTRHAHATVAPDTETEEPGTAPAAAWPPDGASPLDIDARYEDLRAEGYAYGP
VFQCLRRAWRLGDEVLAEAELPQAATGDTDRFGLHPALWEAAAHAVRLTEPARRGSGDGA
LVPFSWHGVTLRATGATRLRLRVRPTGTETARVELADSVGEPVAVIERMAVRRTTADELT
GAATEDADGLFSLTWTPVGTATTTGLPTGRSVPGPTDTAEAPAPAGGTVVLPALDGGATE
LPFMDSDSAGAAGQDAGIVVLPVLGGTAGDGDTEPATGAVAERLLVALQRWLADERNAAR
RLAVVTHGAVAAGEDTEGIRPDVTDLAASVAWGMMRTAQSEHPDRFLLLDLDVDPKSAGS
DLADLVTRAARTGEPQLALRGETFLAPRLCRTRSSATPGSVPDPDGTVLITGGTGMLGRL
VARHLVSTHRARHLLLVGRRGPKAPGAAELREELTALGAEVRIAACDVTDRAELAELLAG
IPAEHALTTVVHAAGVTRNGVLADVEPQDLHTALRARVAGALNLHHLTRDLDLSAFVLFS
SAAGTVGSSGHTGLAAAAAFLDALAHHRRAQGLNALSLVWGAWTPQGPSARPLTDADAIR
LAREGAVPLPASEGLALFDAARTVEAAQLVASKIDASALRARAAAGVLSPLWHDLFRTPA
RRRSANDGDNTGSRTLARQLLDLGAEERNRFVVDLVRRHVAAVLGHGSPAHIDPQRGLMD
AGFDSLTAVEFRNRLAADTGLQLPATLIFDHPTPTALAAFVLAETLGTSGDLDTDDTVTR
GAADEPIAIVGMACRYPGGVASPEDLWRLVADGVDATSEFPADRGWPEDLYDPDPEASGK
SYVRRGGFLDDVAGFDAEFFGISRREALAMDPQQRLLLEVSWEALERAGLKAEDLRGSRT
GVFVGATASAYVADMDRVPETIEGYAQTGNTLSVLSGRVSYTFGFEGPSVSVDTACSSSL
VALHLAVQALRQGECSLAMAGGVTVIASPGGFIDFSRQRALSPEGRCKPFAASADGTTWA
EGVGLLMFERLSDARRNGHRVLGVVRGSAVNQDGASSGLTAPNGPSQQRVIRAALENAGL
GTADVDAVEAHGTGTKLGDPIEAQALIATYGKDRPEGRPLWLGSMKSNIGHSVAAAGVAG
VIKMVMALRNEALPPSLHAGDPTPMVDWSAGSVSLLSEGVAWPRGERVRRAGVSSFGVSG
TNAHVIVEEAPAAEESAVEPVADGGSRLVPWVVSGAGPGGLRGQVERLVSFLDGRPGVDV
GAVAGALAGRAGLRHRLAVVGESAGELVEGLESFLSGDLSAGAAQGVAGPESKVAFVFPG
QGWQWVGMGVELLGCSDVFAEAVGECSAVVEELAGWSVVDVLQGAAGAPGFDRVDVVQPV
MFTVMVALARLWESVGVVPSAVVGHSQGEIAAAHVAGVLCLEDALRVVVARSQALVEICG
QGAMASVALGRAEVEERIAQLESVSVAAVNGPASTVVSGGAEEVAGLVAGLVAGGVRARR
IDVDYASHSVHVEQVRKRIEAALAGVAPRAGRVPVYSTLTGEVLAGPEMDGGYWYANLRG
RVEFEQAVRRLAQDGFTALVECSAHPVLVPGVEQTLETVPGAQVAVSGTLRRDDGGLRRF
LTSAGSLWTTGVDITWPVLLPETQPVELPTYAFDRSRFWLERTESTGDVSGVGLGVVEHG
LISAVVEVAAGGAVVLCGRLSRSRQRWLDDHAVSGQVLFPGTGFMDLVLRAADEVGCQVI
EELVVQAPLVLPDTGQADLQIVIEPAGDDGRRQVVVYSRPAGTDAVWAQHAQAVIAQDST
PEVPPVGVWPPVGAGVIDVSGLYGELAERGYGYGPVFQGVRAAWRLGDTVYGEIALPESV
VQEAARFGLHPALCDAAAHLLQFSKVLDQDGVWLPFAWNGVRLLATGATRARVRITPLGE
GSVRMDLYDVAGEPLAVVEQLTARRLDPAELQPSSTSTAAARGLFALSWPALPTPDTPQP
ADTIVWRPQDSGEADTWGLPAVTDLEDVPASVQVVVLPVSGRDRDVTEVSTAVLAALQAW
LAEDRLARARLAVVTRGAVAVDTGVGPDAGADVVDLAASGIWGMVRTAQSEHPDRFTLLD
LDPHQHADTDALLKALSVSGEPQLAWRDGQLHAPRLVRALTGGFLAGVSGFGAGDTWRVT
TQGTGSLDALAKTPHDAATRPLKPGEVRIEVRAAGLNFYDVAVALGMVDSADGLGAEGAG
VVTETGPGVSRFAVGDRVLGAFPAAFAVRTIADERMLAPIPAGWSFEQAASVPAVFLTAY
YALHDLAQIQPGQRVLIHAAAGGVGMAATQLARHFGADVYTTASPAKWHTLTALGIPEER
IASSRTTDFAEQYLNHTGGSGMDIVLGSLSGEFVDASLRLLTPRGGRYIEMGKTDIRTPQ
QITATHPGITYRAFDLKEAGPTRTGEMLHHLLTLFTHQALTPLPRTEWDLARLPQALRHM
SQARHTGKNVIRIPRPVNPHGTVLITGGTGTLGGLIARHLAHHHHMRHFLLLSRQGPNAP
TAPALHHDLTQTGAQATITACDLTDPHALAKTLADIPTEHPLTAVIHATGHLDDATLTHL
TPHQLTTVLTSKATTAHHLHHHTLPHDPAVFLLFSSAGSILGSPGQANYSTANTYLDALA
HHRRHHNQPATSLAWGLWQQTSGMTSHLDDQDKARLARSALSPMSTPEALELFDAVGTPP
HPLLMVSPLNTQHIPPHPVWQRLSTHRRSAASVEQGPQLAQQLGPLPPAQRFNALLDHIR
RHTATILALPGLEAIDAHRGFMEQGLDSLTAVELRNRLSTSTGLTLPATTVFDHPSPAAL
TEHLLPQLTTADGPEGTDVTDVPGEEDIRRAIAGLSLAQLRDAGLFEPLMVLTGLGSADG
ADDTEEQSAIDDMDVDDLVQAALAEDS
>A0A378RGP1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycolicibacterium aichiense|TrEMBL
MAPTERPTQQTPRFAIIGYAARLPGAADADQYWEVLHSGRDAISEVPADRWDVEEFFDSD
PDAAGKMVTRRAGFVDDATGFDAPFFGVSAREANLMDPQHRLLLETAWRAVEHSGTAPTA
LANTRTGVFVGLATHDFLGMASDALTYAEIEAYLAIGTSSAAAAGRISYRLGLQGPAVTV
DTACSSSLVAIHQACQALLLDECDLALAGGVNVMLSPATMITFSHSRMLAPDGKCKTFDA
AADGYVRGEGCGVIAIKRLDDALRDGDHIRAVIRGSAVNSDGASGGLTVPNGVAQQRVIA
EALDRAGLTPTDINYLEAHGTGTSLGDPIEVQAAAAALGKGRDAGQPLLIGSAKTNIGHL
EAAAGVAGVLKVVLSLEHSELPPHLNFTNPSPHIPWDRIPVQVVDKLRPWERSERPRIAG
VSSFGFSGTNAHVILEEAPVSSPVTAGAAVDDRRFAVLPLSARTPAALVQSAQDYRSWLG
EHPDATLADVCLTAGAGRAHFEHRAALVVNSVESARELLGALAEDLPAPGLVRGDCVDAP
KTAWLFPGQGSQYAGMARELYETEPVFADTMNRCAEAVAGVLEKPLLDMVFGTGLSDSDG
AETLKQTRHAQPAIFAVEMGLARLWQSWGFEPDVVLGHSVGQYSAACVAGVFSLEDGARL
LAERGRLFGELPAGGRMCAVFADPERVESLTDEFPSLSVAAYNGANTVLSGPAADLERAV
AQLSDDGARCDWLDTSHAFHSSLLDPALDAFEAYADGFEFAAPQRILVCNRTGAALGRTA
KLDGQYWRRHARQPVQFAKGVATLAELGCALLLEVGPQPVLTAAALRAWPDPATAPKAVA
SLRRNGADHRQLIEALAGAYVAGHVPDFGALLHEPARKLDLPTYPFQHRQYWYQSKQSQS
PASDAARTEAVQLLEDGRIEELAALLGGDGSTTAAEVLSKLAAQHNRQRSAQSIADIRYE
IRWQKALSSSTEVGEGAAWLLIGDDKAVMGPLVDALTAHGHRHRVLGLPVSDADEERLVA
ELSAAAQDEPALRILHVAALDSDGESSMRSLLRMQHRVLGGTQRLFRAAAAAELRTPIWV
LTQGAQRVGDADTVAPEQSGLWGFCRVAALEYPQVWGGLADLAGTGADDWSRLIKQVVTA
APGEDQIALRDSGVHVPRLIRRTGQPNSTPLELRSEATYLVTGGLGSIGLEIAGYLAAHG
ARQLVLTSRRAPDEAAQRRIDALGEQHGCAVRVIAADVADPHDVARLLATVAAELPPLAG
IVHAAGENSTTPLSSLDSTEIDRVFSGKVWGAWNLSEAAADLKLDFFLSTSSISSVWGSY
GQSAYSAANAFLDGLTWRLRERGVHGISVNFGPWSAGMADQDARAQLDRRGIRTLSPTDA
LAGMADIMAAAGSQGPAEAVVARMDWARFLPIYLQAGRRSLLAEVAREVPESLPAATGSS
GTTRLVEQLTAAPVQQRKKLVLEYLRNTVAEVTRVDASEVREEAGFFDLGMDSLMAVELR
RRLEQAVGKELPATLAMDFPRLTDVADYLLGEVLNLNEKAGAQLAAAPASLAGAATDEPI
AIIAVACRFPGASDADAYWDVLSGAVDAIREIPEDRFDVDEYYDPDQQTPGKIYTRSGGY
LESVDGFDPEFFGISPREAVWIDPQQRLMLEIAWEGLERAGYAPSALRGSRTGVFVGVGA
NEYSHLLSGESVENLEAHFITGNALNAIAGRVAFTLGLEGPAMAVDTACSSSLVAVHQAS
QALHSGDCDMALAGGVNVLLSPASIVAASRARMLAPDGRCKTFDAAADGYVRGEGCGILV
LKRLSDAQRDGDRIAAVIRSSAVNQDGASSGLTVPNGGAQQRLISAALTRAGLGGADVDY
LEAHGTGTPLGDPIEVQAAAAVYGAGRDPIRPLLMGTAKTNIGHLESAAGVAGLIKVVLS
LQNELLPQNLHFQNPSPHIPWDSLPVKVVDEATPWVANGRPRRAGVSSFGFTGTNAHVLI
EEAPQPALGDDPADDPVEVVAPEPVREPLSVLPLSARSGPGLLALAQRYSDWLAAHPDAS
LADVSYTAGAGRSHFEHRAAVVANSVSEAKMLLDDLVANRLRPGVLRGECTDPPTTAWFF
PGQGSQYPGMAKELFETEPVFADTLRRCAQAVDPMLPRPLLDVLFSGDRENAETLRHTSF
AQPAIFAVEMGLARLWQSWGIEPDVVLGHSVGQYAAACVAGVFSLEDGIRLIAERGRLFG
SLPEGGRMVAVFADPDYVERAATGFPRVSVGAYNGRNTVLSGPGEDLEQIVAACSEDGAR
CTWLETSHAFHSELLDPVLDEFETFATQFEYAVPTRPLVCNRTGAVLTAETPINAQYWRR
HSRQPVQFTESVRTVAALGCSVLMEVGPQPILTAAALQIWPETSATPRAIVSLRKGANAQ
RQMTEALATTYICGHRPDFAARFHTSGRRLELPTYPFQRRRYWPKTSGIRSDGTAASGIL
GSAKDLASGDTVYTNVLSVKTQPWLAHHVIYGTVVVPGATYAAMAMAAAGAPARVKEVFF
YEPIILPDKASREVQLTLHPVDDGWKFQVHSRPYGVRESEWSLNSDGTLLSGIDPDAAPP
DTVAPDEAIEQMNRTRPQELFDIFADMELAWGPTWSTSLKSLSVGKGEAIGDIAVGDELG
EHLGTEPIHPVLLDLCTGVAFPAFPATLAAEQGMTDLFLPLRYGQVTIAEKMPRRFYCRA
RWHENTINNETQVFDLDFLDRDGQMLGGIAEFTVKRAPREALMRGLGGDSTRLLYSLGWQ
EIATPAADDTEKTTNGIWLIAGFDALAAEVPGAVTVEEAADPQSWRRVFAEAAERGTAVS
GIVWRSGRQGAGAGHGGVDASTAELAARLEAQIATFLGAAQTALAEGNHTLADGLWIVTE
RAVATEPGEPVDPVQTALWGLGRTLIAEQPSLRVRLIDSDGSDESLRWVAGALGTPVVEP
EMAVRQGRFLVSRLLHWARNGQLPMPRSDDYALAPTERGAIDNLRLAEIEVTPPKANEVQ
VRIEAAGLNFRDVLNVLGLYPGDPGPIGGDLCGVVTEIGSEVTRFEVGQRVFGSMQGAFA
SRLNVPEPLLATVPDGIGAVDAATIPAAALTVRLAFDWAKLKPGDKVLIHAASGGVGLAA
VQMARAHGATVFATASKYKRATLRDMGVEYVYDSRTTEFADQILADTAGEGVDVVLNSLT
SEGFVEATVRATAKNGRFAEIAKRDIWTAEQMAELRPDIDYEIVALDVTMMTDPDHIQRL
MVEVSDGLAKGEWTPVRAEIYPLTEARTAFRRMQQARHIGKIVVQMPKPLQPRGDRSYLV
TGGLGALGLHTASYLAQLGAGDIVLTSRRTPDAEAQQAIDAIAERFHCRIHVFAADVGVE
SEVVELLDKIRAELPPLAGVAHLAGVLDDALLPQQDLDRFRTTLRPKAYGAHHLHRLTKD
DDIEFFILYSSASAVLGSPAQSNYAAANALLDGLVAHRRAQGLPATTVNFGPWGQGGMAS
SQAAVANLSAQGMMPLEPSAALAALGEAIRHGAAQATVLKANWQRTAKVLGGIRPPLLDQ
VLPSGDGTVVGDSELLRQLQELPVAARAGFITEFLQKEVQGFLRLAQPPAASSRFLDLGT
DSLMAVELRNRLFGQFGGKFDISPTAVFDHPTIGELAEHLVSQLPDSDEPPAEPAPDNSA
DAAESAPEPSSEE
>D3CZB6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. EUN1f|TrEMBL
MDNSNPQPHPSGPPAEQVRAAWRARIVRLDPADQVDALLALVVDHLVAVSGREPTTVDRG
APWRALGIYRGAADALRERLAAATGVALPATLLFERPTPRAVASHLRGAVLGWREDAARG
ASSQSDPTAAPVTTRLTDRAGGRAGGQATGPMAGSPGVSAVGPVTDPVVVVGTGCRLPGA
DSAAALWELVAAGRDVTGPLPADRGWDLAGLHHPDPDHPGTTYTRGGGFLPGIDLFDAAF
FGIGPREAVAMDPQQRLMLEVSWEAFEHAGIDPVSLRGSRTGVFTGVSLQDYGSAWHRAP
ADLQGHLLTGNALGVIAGRVSYTFGFEGPALTVDTQCSASLVAVHLAAASLRSGECDLAV
AGGVTLMSTPAMLVEFSRKRGLAPDGRCRAFSADADGTGWAEGAAVVVLTRLSQARARRL
PVLAVIAGSAVNSDGASNGLTAPNGLSQQRLIAQALADAGVAPGDVDAVEAHGTGTPLGD
PIEARALLAAYGDSRPPGRPLYLGSLKSNIGHTQAAAGVAGLIKLVEAMRHELLPASLHI
TAPPRTSTGAAAPSSC
>A0A0N1NPH4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinobacteria bacterium OK074|TrEMBL
MLLVERLSDARRNGHRVVAVVAGSAVNQDGASNGLTAPNGPSQQRVIRQALAGAGLKAAD
VDVVEAHGTGTPLGDPIEAQALLATYGQDREQPLWLGSLKSNIGHAQAAAGVGGVIKMVM
AMRHGVLPRTLHVGEPSSHVDWTAGQVELLTEERVWPETGRPRRAGVSSFGISGTNAHVI
IQQAADQADFIEAEGQSDPLDLVCEDGRTVPLPLTAADPEALRAQAVRLGELLAGDPALA
PRDLGLSLSTTRCTLEHRAVLLAADREELAQGLSALAAGEPDPLVLASGTERSGRRLAFL
FAGQGSQRLGMGRELYETYPVFTAAFDAIDAELPFDLREIVFGEDAERLNRTEFAQPALF
ALEVALFRLLESWGVRPDVLAGHSIGEIAAAHVAGVWSPADACQLVVARGRLMQALPSEG
TMVALQATEEEVFPLLNDHVGIAAVNGPRSVVISGAADAVEEVTAHFRAQDRKTTTLRVS
HAFHSPLMEPMLAEFRAVAEQLTYGEPGLAIVSTLTGADADPAELLTPDYWVRHVRQAVR
FGDAVRVLAGQGVARFVEIGPDGTLTALAQACLETDGDNGRDGRDGPPLLLLPALRKDRP
EGRSVLIAVAGLFTRGGDVDWRAVFTGSGARTVELPTYPFQRRSYWPTPALDRFGGDVAG
LGLSATDHPLLAAAVAPADSEGVVLTGRLSLRSYPWLRDHTVAGAVLFPGTGFLELVLRG
ADQVGCDRVEDLTIAVPLVLPEHGGVRVQVLVGGPDATGHRGVSVFSRPDDAPEDEAWTL
HATGVVSDEAQAPRPGGTFDFGAWPPPGASAESTEGAYERFAGLGLSYGPVFQGLRAVWR
RGDEVFAEVALPEDHEELADRFGLHPALLDSVLHAVLRGLFGDDGSLRLPFSWSGVSLWA
SGARELRVRVGQLASGAVTLELADPAGGPVASVESLVLREAADGFAPAGGNRMDALFQVD
WTRVPTAAGPAPEVRTGLPAPGEAVPGEVLVQVERPVGGDAFAAHSDPFAAHTVATSVLE
LVRAWLADERFEGARLVVVTEGAVAVDEPSADPALAAVWGLVRAAGAENPGRFALVDVDG
TTESWAVVGSALASGEGEFAVRGGAVFVPRLGRAATGTALTAPAGESSWRLDVVEKGTLE
GLALTAAPGVGDELAAGQVRIAVRAAGVNFRDVLNALGMYPGDAKDFGLEGAGVVTGVGE
GVTELAVGDRVFGMFSGAFGPVAVADARRVARIPVGWSFAEAASVPIVFLTAYYALRDLG
GVRAGESVLVHAAAGGVGMAGVQLARHFGAEVFGTASAGKWGTLRELGLDGAHMASSRDT
EFEAAFLAVTGGRGMDVVLDSLAGEFVDASLRLLPRGGRFLEMGKTDVRDPEAVAAGYPG
VAYRAFDLMDVAPERIGEMLADLVGLFEAGALRPLPVTCWDVRRAPEAFRYLSQARHVGK
VVLTVPVALDPDGTVLVTGGTGGLGALVARHLVTEHGVRHLLLASRRGLEAPGARELVVE
LAELGAAVEVAAADVADRDQLAAALHTVPAGHPLTAVVHTAGVLDDGVVAALTPERMARV
LRPKVDAVTRLHELTRGADLSAFVVFSSVAGTFGGAGQANYAAANVFLDAFATRRRAAGL
PATSLAWGPWAPGAGMTAELTDADLRRMARAGMQPLAPERGLELLDAVLELGASAERAAL
LPVNLDIAAFRKRGQDVPDLLRALVRTPARRVAKTKSAVGVGGAAELRQRIGGLAAVERE
KFLLDLVRGQVAAVLGHTSAADVEADQAFKALGFDSLTSVELRNHVNTVTGLRLPATLVF
DHPTPAVLARHLLAELSDGAATDTAFASAALPAPTGVDDDPVVIVGMACRFPGAVGSPED
LWRLVSEGRDAIGEFPADRGWDLDGLYDPEPGKTGRTYTREGGFLYDAPLFDAGLFGIAP
REALAMEPQQRLLLETSWEVFERAGVDSSALRGSRTGVFVGAITQDYGSFMRAGDHDSDG
YLLTGSTGSVASGRIAYTFGFEGPAVTVDTACSSSLVALHLAVQALRSGECDVALAGGVT
VMSGPEMFVEFARQRGLAVDGRCKAFAEGADGTAWAEGVGLLLVERLSDARRNGHRVVAV
VAGSAVNQDGASNGLTAPNGPSQQRVIRQALAGAGLKPADVDVVEAHGTGTPLGDPIEAQ
ALLATYGQDREQPLWLGSLKSNIGHAQAAAGVGGVIKMVMAMRHGVLPRTLHVGEPSSHV
DWTAGDISLLTENVDWPQPSDRPRRAGVSSFGISGTNAHVIIQQAPDSATEPAVSETEPQ
SDPAIVPVVVSGAGVAAVREQAERLWAWLGRDGEDAGDSSDMAGADVRLADIGLASVATR
TVLDHRAVVLAVDRAELRQGLRALADGEDTPGLVQSAEARAGRTALLFGGQGSQRLSMGR
ELHGAYPVFAAAFDAIDAELPFDLREIVFGEDAERLNRTEFAQPALFALEVALFRLLESW
GVRPDVLAGHSIGEIAAAHVAGVWSLADACQLVVARGRLMQALPAGGAMVAVQAAEDEVL
PLLNDHVGIAAVNGPRSVVISGAADAVEEVAAHFRARKTTTLRVSHAFHSPLMEPMLAEF
RAVVSELTYARPQLAVVSTVTGAPATADELMSPEYWVEHVRRTVRYGDAVRTLADQGVTR
YLELGADGTLTALAQATLDEPEAAVLAPALRKDRGEPGTLLAAVATLFTRGADVDWRAVF
EGSGARAVELPTYAFQRRRFWPEAVQRPGDLAAAGLGAAGHPLLGAAVELAGGGTVLTGR
LSLRSHPWLRDHTVVGAVVFPGTGYAELALRAGDEVGCGRVEELTIAVPLVVPEQGTVRL
QVTVGSAEESGRRTVEVHSRPEDAPDDTPWTLHASGLLAPDAVSEAPQATTSAASDDMAF
ARAEWPPKGAEPCQLADVYDRFAAAGLAYGPVFQGLRAVWRRGDEVFAEVVLPDEHDALA
GRFGLHPALLDSVLHAVLFGPVGESGAGRLPFAWTGLSLHASGARALRARVVPAGADAVT
LHLADPAGGAVASVGALALREVPSELTSAVPSGVYRIDWTSLPSSDAVVSATEDAPTPGR
TVLLTDHAPEYGRPSGEDRAPAVPARTWSELTRAVHDGDPVPETVILPWIGSASGSAAEA
HAVTSAALDFVQTWLAAEEFADARLVVVTRGAVAVAPDEEPDPVAAALWGLLRSARTENP
GRFALADLDGTPESWMTVLASLASSSDRPGVATEDELAVRGATLLVPRLTPTALPAPGRA
LDRDPEPAFRADDTEPHPTRRPPQLADGTVLITGGTGGLGALVARRLVTEHGVRRLLLTS
RRGADAPGATELAAELGDLGADVTIAACDVAERAALEGLLAAVPADRPLTGVVHTAGVVD
DGVIASLTEERLRTVLRPKVDAADHLDALTRELDLAVFVLFSSVSGTFGGAGQANYAAAN
AYVDAVALRRRRQGLPGVSLAWGPWAPGAGMTADLTDADLRRMARGGVRPLAVDQGLAVL
DAVLRAPRPAEPAADHLLPVNLDLAALRELPELPPLLRGLVRGPVRRAAHSGGHGGAHGD
GGGELRARLVELPAAEREPFLLDTVVGLVAQVLGHASAADVDSGQAFKMLGFDSLTSVEL
RNRVNAVTGLRLPATLVFDHPSPAALARHLLAELAGAGAESRGTTSMVRQDTGDDPIVIV
GMACRFPGGVESPEDLWRLVSEGGDAIGDFPADRGWDLETLYDPEPGRLGTTYVRQGGFL
YEAASFDAELFGISPREALAMDPQQRLLLEVSWEVFERAGIDPTALRGSRTGVFAGVMGQ
DYNSCLREGEHDSDGYLLTGNTSSVHSGRIAYTFGLEGPAMTVDTACSSSLVTLHLAAQS
LRAGECELALTGGVMVMSTPDTFVDFSRQRGLAADGRCKSFGAGADGTAWSEGIGMLVLE
RLSDARRNGHQILAVVAGSAVNQDGASNGLTAPNGPSQERVIRQALAGAGLKSADVDAVE
AHGTGTPLGDPIEAQALLATYGQDREQPLWLGSVKSNVGHTQAAAGVGGVIKMTMAMRHG
VLPRTLHADEPSPFIDWTAGDINLLTENVDWPRPSDRPRRAGVSSFGISGTNAHVIIEQA
PDAVPAGEPDPSELPVATAELPVTPVVLSAATPGALRGQAERLWAHVEADTAPRLSDLGL
STTLRPWLEQRAVVLAADRDSLLRGLRAVATGEHDPDVLHGTPGRSGRRLAFLFAGQGSQ
RLGMGRELYEAFPVFAAAFDAVDAELPFGLREIVFGDDAEQLNRTEFAQPALFALEVALF
RLLESWGVRPDVLAGHSIGEIAAAHVAGVWSLPDACQLVAARGRLMQALPPGGAMVAVQA
SEDEILPLLNDRVGIAGLNGPQSVVISGAADAVEEIAAHFRAQDRKTTALRVSHAFHSPL
MEPMLAEFRAVAEGLAYAEPRVSIVSTVTGEVAAAEELMSAEYWVEHVRRPVRFADAVRQ
LAELNVTRFVELGPDGTLTALAQGSLDGDGHLLVPGLRKDRAEAGSLLAAVAGLHLHGGR
VDWAALFAPTGAAVVDLPTYAFDHERFWPEGAKLGGRPADGSDGRADAGFWTAVEQGDAR
ALADSLGVAQDALDGLLPALSSWWRGQQEQSRVDDWLYGTSWKPLGAMSGTALPGRWLAV
LPAGRRDDAWCAAVLAGLAAHGAEPVPVGYEPGTDRATLAAQLTLAAGDGPVAGVLSFLA
LSERDLSERALPEGALLEGDLRGADTSGFTSAASSADVDGGAVPAGTSLGAAGHDIPPGP
AATAVLVQAFGDAGIGAPLWALTRGAVRVNRSDRAPDPEQGAVWGLGRVTALEHPDRWGG
LVDLPAAVDRRAVGRLVGVLAGRSSKSEGGGEDQVAVRATGVFGLRLGRTAPATLGGGWR
PSGTVLITGGTGALGARVAHWAATQGAEHLVLVSRRGLDAPGAAQLRDRIAELGARVTVA
ACDAADRDALAALLSVHPVDSVVHTAGVLDDGLVEALTPERFATVLRAKAVAARNLDELT
RDRDLSAFVLFSSFAGAIGSPGQGNYAAANAYLDTLAEQRRAAGLPATSVAWGPWAQDGM
AADGSVEEYLRRRGLTGIDPEPALAAMERLAGGADAAAVVARIDWTRFAPAFTAGRSAPL
LAEIPEAGAALENVSSGADADALRDRLAGLGADERTTALVELVREQAALVLGHARADAVD
PARAFREAGFDSLTAVELRNRITAVTGLRLPATLVFDYPAPADIARYLATEFAGSGGEFG
GDNGVVAELDRLAQVLTAETGTDGDTHLEITAKLRGLLALWTGADTVDEPGDDAGAELDE
ATDDEMFDLIDKEFGVL
>A0A6C0QEL6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. S4.7|TrEMBL
MTDDVLLRRSLNAIRVLREQMRELRSAAEEPIALVGMGCRFPGGADSPERFWELLRDGRD
AITDVPPERWSAHRFHSQARDEPGTAYTRKGGFLTEDVHAFDGPFFGITDAEAREMDPQQ
RLLLETSWEALESGGLLSNGLSGERIGVFVGVSGSESFLLNRPLDDTGPYTATGVAPSIT
AGRIAYALGLRGPALAVDTACSSSLVAIHLAVESLRRGECTAAVAGGASAMMSPDVFVAL
CRMEALAADGRCKVFDAEADGYVRSEGAGMVALMRASDAAAVRAPVLALIAGSAVNHDGH
TAGLTVPNGRAQRELITAALTAARTRPDEVDYLEAHGTGTPLGDPIEVRAAAEVFCADRD
PATPLLIGAVKSNVGHLEAAAGVAGLIKTVLALKHAQVPGNLHLNQLNPQLRADRLPVDF
CDSARPWPASADRPRVAGVSAFGFNGTNAHLVVREAPAARTPQTGTGDRPAHLLALSARD
PRGLRESALRLAHWLTEHPEASVADVCHTVSARRPAFPYRTALVVRSADGLADRLRALAD
EPARPPERTTGPVAFLLNATGDRAWRSADRLYASHPAFRDHFDRCDELLRPVVGEPLAAA
LAQGPSGSPLFRDAVALAYQIALVRALDGWRVSAGAVAGSGPGELAAACLAGVFDAGTAG
RLLAARHEDAPVPALTEARGPRLRLLHGPLADAVSAERAADALFWARESEGTTTRALTEA
LAGHGYGTLVSLGDAGTDDEATHHGNALAHWAVPGDDVWEELLTGAADRYLAGADVDWSD
LDLGHDRARLTLPTYPFQRRSYGPLGTAAPAPARDFGSARPIGELGLRTVPSPLDQHQFD
TVVSRALLPELADTAGVLHVGYYQEMLAAATATDGTGEGFHVRDVNFHQALRLSGRQERT
VQLVVEPADDKGWADFAFYSRPTAGTEWDRHVRGSVRPGPADRTEEESAPLTGQGRELIL
SRCTERVGGEEFYKLMRDRGVALGPSVEWVEEAWAGDGEVLARLRPAGEAAVPAGRPGRA
LPTHPGVLDACVQLYALAAGAALADDDLFITARLGEADAVSAAVTGPLWCHVRLRSAVGQ
RLVGDHVLCDDRGRIVASGRDTEVQVISPQESLSLLAATDGEQSGDHPGEILARYRAAAP
ADRPRVLMDFLTETAAGLLRQPADEIPAGRPLAELGLESLAAMELRKRIRTGTGADLPVE
LLVDGPSLDELARHIASEIDTDDEPDTTCSAPRDYDLDSARWLGTAVRETSRLRLFCLPY
GGRGASLYRDWPHELDGGVEVCPVQLPGREERADELGIVNVDEAVESIAQVLKPYLDRPF
AFYGHSMGGLLAYRMAHRLGAEHGSLLRHLFVGAFSAPTGAVNPLDDRILAVMRSLGFPG
MPAQQDLLRLRRERPGEYEQALRREFDDRVAAKLDASTSGCGYGDLRIVQSYRHDPAEAP
LATGVTAFHGAGDPVVPEADMRAWEGLTSGPFELRVVPGDHFFLHGDQSGPRLLAAFSET
LR
>F8GKF2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nitrosomonas sp. (strain Is79A3)|TrEMBL
MSEFIKFVYTPIEHGDITLIISACRSGGVGVLNAEYEINSTLIVNQLDLLAKKSCHGYGL
KVDQLDEYLIAGIHDCTKKGLHWLIVDSKIVSIYKAFFQELRHAGVKVLAELKQSCWTNQ
PLDQLVDGLVVKGNEAGGFVGENSSFILFQKWHKQTTLPLYIHGGLTPQVAAACSAVGAA
GGVFDSQVLLMDESRLPDFLRSMFSNLAGNETVLVGNGEVGEYFRLLVRPGFIDVQAFMR
EGEGQGYDTLKRLVNTKINWKELRKGLLPIGQDICFAGPWQKKYKHIVDLFKAVDTAIEE
NLCQAIEAKIISQNAPLAEALGIPYPLVQGPMTRVSDSAEFAAAIANGGALPMLAFALLK
GSALRKLLSETDHLLGDNPWGIGLLGFVPQELFEEQLTLAIEFHPRYAIIAGGRPDQAVR
LEAAKIPAFLHVPTADLISLFIQEGARRFIFEGRECGGHIGPLSSFVLWSAMVDRLLIEL
QNGKVQGDELEILFAGGIHDAISSAIVQVLVAPLAAKKVKIGILMGSAYLFTREIVSSSA
ILPLYQEEVIRCTRTVNLESGHGHASCCAYTPFAKEFFRKRSLLRKKDVPADEGRKILDD
LIMGRLRIASKGSIRKGAKGKLHYLDEDKQHEEGMYMLGQVATLRSEVTDIRLLHQQVTE
DAAELLVTRFSKISRESQLLTEKPVDIAIVGMACLLPKANSIEDYWNNILNKVDAITEIP
LHRWDWRLYFDEDRSAKDKIYSKWGGFLDDMPFDPIRYGMPPKSIESIDPMQLMALEVAQ
RTLIDAGYQDRDFNRDRASVILGVSGGTGDVGTQYGLRAELPRFYGSLPENIADRLPEWT
EDSFAGLLNNVSAGRIANRLNLGGVNFTTDAACASALAALYQSVSELTSGRSDFVITGGI
DTVQGPFGYLCFSKTQALSPRGRCSSFDASADGIVISEGIAMVALKRLNDAERDGDRIYA
VIKGTGGSSDGNAKGMTAPLPEGQLRAMRRAYVQAGFDPNTVGLFEAHGTGTVAGDTAEL
ESTMKLIKESEYNPKQAVIGSVKTMIGHTKATAGIAGLIKAALALHRRVLPPHRWASQPN
QVLQQADCPFQLIDQAQPWIVSETVPRRASVSSFGFGGTNFHIALEEYTQEYREWLRPVT
SQQWPAELLLWSDDSRGGLVAQLGDIEKALQNIQSLELRDIANSLAKKWQMNNEIVAIVA
KDLTELIEKIKVLLAYFQDKNVKLPAGVYHGSGKVPAGKLAILFPGQGSQYTGMLREVSL
HFPIYAEILTEADRILNEAFSHRYGESKRLSHFIFPRGCYSEEAKAKAQQTLTSTDIAQP
ALGAIEAGLWKLLQTFGIEPDMLAGHSYGEFVALHASGAIDLNTLMTLSSARGRFIIDAA
KKEINELGTMLAVQACREDIEAALSDQNDVVIANHNAPLQSVLSGSHSAIESAEKKLLAA
GIITNQIPVAAAFHSSLVKPAQHALANLIDNMEWQPCRIPVYSNTTAKPHAAEVSVTKKL
MAEHLVSSVEFVSEIESMYQDGARIFLELGPKSVLSKLTDKILTNQPHKAISIDDGSGLS
GMLNALGQLICAGVNLDVMKLFSHRDCMSGDPAKLESLQRHNAVPKHVWMLNGSGVRQAN
QPIKQIGVTADQVVNQSLTIATVQASTDEAQVSEYQINQVSQVNAAGLANAKQIQQQKTW
KKENQMRERRPLTNSGNSAVMSEYFETMRQFLETQERVMTAYIGEPIVDQGSIREQRIIS
SYTPSKVQAYEAVQEQEPAKQNQVMQIPDKKTVAAVSANETTIQNTSNVTSAQVIDIADK
SKEKNKVASSLDRDSITKILLGVIEDKTGYPPDMIGLDQNLESDLGIDSIKRIEIVGTLL
QKLPENYRQELGENRSKLNTQSTLNGILDILANLKAGGTVTVPFNFAEVGGMTSVISHPP
RHIIESKQENIDKTALKQLKQGHYLITEDELGIADELMKKLISRGCTVNLLKRETLSHDD
LLINWCNSHKNEFHELAGVIHLAQLSRDWLKTNATLDEWRKQLQINEKSFFVLLHDFSDK
FVKDTHIVSASALGGFFNRNGSISHGGLSIQSGAVGMLKSLFDERPTLRIRAIDIDPSQN
SSEISSILLDEMELVGGRLEVGYPDGKRTVFHTVFSPVNIDVANSKKLQDIIVLATGGAR
GVTAEVLRELALPGNTLILTGRSALADKEPEILKTLTTADALRQYFISEARSNNTSITPA
KIGQKINAVLATREMYSNIEDFKQRGAIVEYHAVDVTNEDEMHHLLSDVYTRHGRIDGVV
HGAGIIEDKLLADKKIDSWTRVVETKVMGLLILQKYLRLESLKFLTVFSSVAGRYGNSGQ
SDYATANEIMNRLCCQLKMNWNNQVNIIAFCWGPWGQTKFGAGMVTAETEAKFAKNGVRL
VTAGIGHQLFKDELMRINNTDVEIICGEGPWEKRESTIGEIKKSSQISDAHHIGPLIGRS
EKVILTKNNQAINFHIDAKQNYLQHHRIDGIPVLPAAAALEMFAEIAQHLWNGWKVVEIQ
NFCLLKGIELKDDVRNFSIVISPPPYGSSAGFEVNAILQSEKKDSKPLIHYKSTLRLEQK
LPHGIEQVNKFHSEKKLTVTKAYNELLFHGPCFQVIEDIEGLSTLGASATVKTTCPANWI
INADKHDKWIFDPAIIDSAAQMGILWTRNFRDETALPTKFGRVVRYQETLPDQLYMEFEL
IPSQDSNLLRANIYFSDIAGQMVFLIENMECISSKALNRLGGSARITSNAIELFSGEL
>A0A1V2RN16|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. MP131-18|TrEMBL
MRAWTIDHTRPDHLTLAEAPEPAPAPHQALIRVAAFSINYGEVVSVVPDGELGTVPGWDA
AGIVERAAADGSGPAAGTPVVSLAADGAWAELRAVDTALLGAVPQGADLGAISTLPVAAG
SALRGLHRLGPLLGRRVLITGAGGGVGRFAVQLAARGGAHVVATTTDPAKEQTLRGLGAD
EVVIGTDGIAGLTGPVHGVIDLVGGDHMVAAYRTLGRHGTLIAMGHTSGRGESFAESDFS
GLLGTDRSIATFFLLDDADGLGADLSWLAGLLAGGELDAQVGWRGAWTRTPEAITALAEG
RVPGKAVLDLPAAG
>A0A3E2YHD5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MW-13|TrEMBL
MSTSADKVVEALRASLKETGRLRQLNQQLTAAAREPIAIVAMSCRYPGGVATPEQLWDLV
ASGSDAVGGFPTDRGWDLDNLYDADADRAGRSTTREGGFLYDAAEFDAGFFGISPREAVA
MDPQQRLLLETSWEAFEYAGIAPASMRGQKVGVFVGTAANGYGMGPQTELEGTDEGYLLT
GTATSVVSGRIAYALGLEGPAVTVDTACSSSLVALHLACQALRQGDFDLALAGGVCIMAT
PSPFVGFSRQRGLAPDGRCKSFAAAADGTGWAEGVGLLLVERLSDAQRKGHHVLAVVRGS
AVNQDGASNGLTAPNGPAQQRVIRQALANARLTTADVDAVEAHGTGTVLGDPIEAQALLA
TYGQDRPADRPLLLGSIKSNFGHSQSAAGVAGIIKMVMAMRHGVVPSTLHVDSPTPKVDW
SAGAVSLVTEARPWPATGRPRRAAVSSFGISGTNAHTIIEEPPAPDTDAAAAPEPAVTLP
VVPVLLSARSDAALAGQAGRWARWLAADEDLRPLDVGWSSAVSRSALDNRAVVAATDRDE
LLAGLRALASGQSSGVLVAGQAADRGPLAVLFSGQGAQRAGMGRELYGEFPVFAAALDEV
CGHLDGLLPQPLKPVLFAEPGTAEAGLLDQTVFTQAGLFAVEVALFRLVESFGIVPDFVG
GHSIGEITAAHVAGVLSLADACALVAARGRLMQALPVGGGMLAVNASEAEVLPTLDGFTD
RVGIAAVNGPSSVVVSGAVDALDEVERVWRDRGVRTRRLTVSHAFHSPLMEPMLDEFRSV
LAGLTFAAPVLPVVSNLTGALATAEQLRTVDYWVRHVREAVRFADGITALRTAGVDTFLE
IGPRSVLTAMTQDVLGSQPVDPADDVTPVVAVPALRADRPEARALLAALAELHVNGAAVD
WPRVYADTGATTVGLPTYAFQRQRYWPEQLPVSVAGPVSPDVIDVEFWSAVERSDVAALA
AQFGDDGLDVLAPALPVLSSWRRARLRDAVVDGWSYRVVWKRTAAPVAAAPIGDWLLLEP
AGEPAVTQWTDALTAALGAAGGTVHRLPVDPLTDREGLAARLAELPADRRFAAAVSLLGL
LDRPHPGHPAVPTGTAATATLVQALHDADVALPVWTLTRGAVGTGDADGVRSVAQGGLWG
LARVAGLEHPQLWGGLVDLPERPDAAGWDRLVGVLAGAGDEDQIAIRPSGVFARRLVRAD
PAGVGTLERWQPSGTVLITGGTGALGAHVARWVAANGAAHVVLTSRRGERAPGAAELRDE
LAGLGARVSLVACDAADRAQVEAVLRDIDADDAPLTAVVHAAGVGQLAMLADTDLAALAA
VLDGKITGAVHLDELLGDRPLDAFVLFSSIAGIWGSGGQAGYAAGNAFLDALAERRRARG
LAATAVAWGPWADGGMASGEGQELLARRGLTAMSPAQAVYALRSAVGRSVPSLTVADVDW
SLFTPAFAAARPRPLLDDIAEARAALRGTDEEPADGAGGGLRQQLLTLPRAEQDRHLTDL
VRTVAATVLGHTGPELVKANRAFKELGFDSLTAVELRNRLSAATGLSLPTTLVFDYPNPA
ALADHLSAALRLHEVDAVTTWGPTGPVDDDPIVIVGMSCRYPGGVTSPGELWDLVATGRD
GITGFPEDRNWDIARLLAVDAEGRPVSHTREGGFVPGATGFDPGFFGISPREALAMDPQQ
RLLLEASWEALEQAGVDPDRLRGSRTGVFVGASPSGYGTTDTPEELAGYQLTGGAHSVIS
GRVSYTLGLEGPAVTVDTACSSSLVAVHLAAQALRGGECDLALAGGVTVMVTPGAFVEFS
RQGGLAPDGRCKSFAASADGTGWSEGVGVLLVQRLSDARRQGRQVLAVLAGSAVNQDGAS
NGLTAPNGPAQQRVIRAALANARLTVADVDAVEAHGTGTTLGDPIEAQALLATYGQDRPA
DRPLFLGSIKSNIGHAQAAAGVAGIIKMIMAMRYGLLPSTLHLDEPTPHVDWSAGAVSLL
TEARSWPDVDRPRRAAVSSFGISGTNVHLILEQPPAPPAGDEADAGEPTPAAARSLAPVL
LSARDGAALSAQAARWAAWLAADENLRPLDVALSSVVSRATLDERAVIAATDRDDLLAAL
TALAAGDPSGGVVAGAAGPRGQLALLFSGQGAQRAGMGRHLYAEFPVFAAALDEVCGHLD
PLLPRPLREVLFAAEGSAEADLLDQTVFTQAGLFAVEVALFRLVESFGVVPDFVAGHSVG
EITAAHVAGVLSLADACALVAARGRLMQGLPAGGGMVAINASEAEVLPTLDGLTDRVGIA
AVNGPSAVVVSGAVDALEEVDRAWRGRGVRTRRLTVSHAFHSPLMEPMLDEFRSVLAGLT
FAAPLLPVVSNLTGALADGDELRTPDYWVRHVREAVRFADGVTALRAVGVDTFLEVGPQS
VLTAMAADVLPADDGVLAVAVQRRDRPEAHALLAALAELHVHGVPVTWTQWFADTGATRV
ELPTYAFQHQRYWLSPVGQAADVSGAGLGVARHPLLGATVSVAGEDMVVLTGRLSLSSHP
WLGDHVVSGAVVVPGTALLDLVVRAGDEVGASRVRDLTVLAPLVLPASGGGMRVQVRVGP
VDATGARPVTVHSQFEEDPEAGWTRHADGVVGLPTTDEPTVGAWPPAGAAEVDLTGWYPT
VAGHGLAYGPVFQGLRRAWTADGTVYAEVALPDTVIGDPAGFGVHPALLDAALHPVGLLP
AEAAGDGPRVPFSFEGVQVHTIGARTLRVRLTASGSSVRLVAVDEAGTPVVSVDSLTLRE
MTAASTPDQAHRSLFEVSWQPEQVVPADAGYGWAVLGGDATDGTPLTSAYRDVAAVVEAV
TDATAPAPAALLLPVSPATEADVPDADVPDAVRAATAAVLREAQGWLVADALADCRLVVV
TRGAVAAHPDDRVTDVAAAAVWGLLRSAQSEHPGRIVLADLEPDADLGPELLALLAGFAA
DPGAGGQLAVRAGTAYVPRLVRAAGGAQAAPVVGAGTVLVTGGTGSLGALVAEHLVTAYG
VRSLVLASRQGPAAPGAADLVERLTGLGAAVQVATADVTDRTQVDALVRRITADGRLAGV
VHTAGVLDDGVVTGITADRLADVLAPKVTAGWWLHEATAELDLDLFALFSSIAGVLGSPG
QAAYAAGNAFLDALAQLRAQRGLPAVSLAWGMWDTDGMAAAINDTDRARASRAGLTPMTA
PVGLGLWDAALAHGGAALVPAVVDLPAMRAQTTAGRVPPMLRTLVGSTANRRRPAAGGWA
DRLAGLDPQEARTQVALLVRGLIAQVLGHSGADQVPADRAFRELGFDSLTAVELRNRINT
ATGLRLTSTLVFDYPTPGALSDHLYEELSGQVAEQRDAVATANVDEPIAIVGMACRYPGG
VTSPEQLWQLVATGADGIGEFPADRGWDLDRIFHPDPDNPGTSYTRHGGFLYGAAEFDPA
FFGISPREAVAMDPQQRLLLEASWESFESAGVDPVRLRGSRTGVFAGLMYHDYASQVQDL
PEGVGGYIGTGTSGSVLSGRVAYTFGLEGPAVTVDTACSSSLVALHLAVQALRSGECDLA
LAGGVTVMATPGTFIEFSRQRGLSADGRCKSFAASADGTGWSEGVGVLLVQRLSDARRDG
RRILAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQALANARLTTADVDAVEAHGTGTTLG
DPIEAQALLATYGQDRPEDRPLWLGSIKSNIGHTQAAAGVAGVIKMIMAMRHGTMPRTLH
VDEPSPHIDWSAGAVELLTEAREWTAPGRPRRAAVSSFGVSGTNAHVIIEQPPAEDRTEP
ADAAVPPLVPVLLSARTEAAVAAQADRWARWLAADETPRPSDVGWSSLVSRSTLEHRAVV
TATDRDELLAGLRALAAGSPSGTVVTGTGSPQGPLAVLFSGQGAQRAGMGRELSAEFPVF
AAALDEVCGHLDPLLPRPLREVLFAAEGSAEADLLDQTVFTQAGLFAVEVALFRLVESFG
VVPDFVAGHSVGEIAAAHVAGVLSLADACALVAARGRLMQALPAGGGMLAVAAPEADVAS
SLDGRTDRVGIAAVNGPSAVVVSGDVDALDELEQVWTDRGARTRRLTVSHAFHSPLMEPM
LDDFRTALEALTFRAPLLPVVSNLTGTVVDPQEITRPDYWVRHVRGTVRYADGITALRDA
GVHTFLEVGPQSVLTAMNAELLAEGTLTLATQRRDRPAPQALLHALAELHVNGVPVTWQQ
WYAGTRPERVDLPTYAFEHERYWLGAGRPRTGDVSGAGLGVAGHPLLGAAVTVAGEDVVV
LTGRLSVSTHEWLADHAVAGSVVVPGTALVELAVRAGDEVGASRVRELTVAAPLVLPASG
GVRVQVRVGAADASGSRAVTVHSQAEGDPEAEWVRHAEGVLEAALPDEPTIGAWPPAGAS
EVDLTDWYGLLAGHGLVYGPVFQGLRRVWASGGEVFAEVGLPDEAAGVAASFGVHPALLD
AALHPVGLLLSGAESGGPRVPFAFEGVQVHASGARVLRVRLSREGSGVRLVAVDESGAAV
VSVDSLVLREMTGLTVPNLAARSLFEVAWQAEEVSEAGDAAGWALLAVDGLPAGLDLPTF
PDVDALLATAAPAPRALVLPVPADAPGVAVPESVRAVTSDVLAVVRSWLAAEALAESRLV
VVTRGAVAARDGDAVTDLAGAAVWGLLRSAQSEHPGRIVLADVDGDVDAGLVAVLARVAE
DAAGGQVAVRAGRVFVPRLVRVSVPASESSPVLGEGAVLVTGGTGALGALVAEHLVVRHG
ARSLVLVSRRGPDAAGAGELVERLAGLGAVARVVACDVTDREQVFGLVAEVASAGRLAGV
VHTAGVLDDGVVSGISAERLAGVLAPKVSAGWFLHEATAGLDLDLFVLFSSIAGVLGSPG
QAAYAAGNAFLDALAVYRRRAGLPAVSLAWGMWETAGMAASVGEVDRARSARSGLPPMSA
ETGLELFDAGLLTGRSALVPAVVDVPALRAAASGGVMPPMLRALVGTTTTRRQAGQGGDW
ANQLVDLAPEEARAQIDVLIRGLVAQVLGHGGAESVPADRAFRELGFDSLTAVDLRNRLN
AATGLRLASTLVFDYPTPAVLADYLYELVSGQITARRSAVVTAGTDEPIAIVGMACRYPG
GVETPEQLWALLAAGGDGISEFPTDRGWDLGNLFDPDPDRSGTSYTRHGGFLHGAADFDP
AFFGISPREAVAMDPQQRLLLEASWESFESAGVDPQRLRGSRTGVFAGVMYHDYASRLED
LPPDAEGYVGTGTSGSVLSGRVAYTFGLEGPAVTVDTACSSSLVALHLAAQALRSGECDL
ALAGGVTVMATPGTFIEFSRQRGLSQDGRCKSFAASADGTGWSEGVGVLLVQRLSDAQRE
GRNILAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQALANARLTTSDVDAVEAHGTGTTL
GDPIEAQALLATYGQDRPADRPLWLGSIKSNIGHTQAAAGVAGVIKMIMAMRHGVVPATL
HVDEPSPHIDWTAGAVTLATEATPWPVVNRPRRAAVSSFGISGTNAHVVIEQPPVPVVVG
EVVGRVVPPVVPVVLSARTDGALAGQAGRWVRWLSADAAVRPVDVAWSSITTRPALEHRA
VVTAADRDDLIAALTALAAGDPSGVVVTGAAGQRGQLALMFSGQGAQRAGMGRELSEAFP
VFAAALDEVCGQLDPLLPRPLREVLNGSPGSEEAGLLDQTVFTQAGLFAVEVALFRLVES
FGIVPDFVGGHSIGEITAAHVAGVLSLADACALVAARGRLMQALPAGGGMLAVNASEAEV
LPTLEGLADRVGVAAVNGPSSVVVSGAVDGLDEVEQLWRGRGVRTRRLTVSHAFHSPLME
PMLDEFRAVLAGLTFAAPLLPVVSNLTGALADGDELRTAEYWVRHVREAVRFADGVTALR
AVGVDTFLEVGPQSVLTAMAGDILPADDGVLAVAVQRRDRPEGHALLAALAELHVHGVPV
TWTQWFADTGARRVDLPTYAFQRERYWPAAGRPRAGDVSRAGLGDAEHPMLGAAVDLAGD
DEMVLTGRLSLDTHPWLADHAVSGVTLVPGAALVELAVRAGDEVGLSRLRELTVAAPLVV
PDAGSVRIQVRVDGPAGSPERTVTVYSRRDDDAEAGWTRHADGVLEAALPNEPGIGAWPP
AGASEVDLTDWYGLLAGHGLAYGPVFQGLRRAWTADGAAYAEVALPDDAAGDAARFGVHP
ALLDAALHPVGLLLSGAESGGPRVPFAFEGVQVHASGARVLRVRLSREGSGVRLVAVDES
GAAVVSVDSLVLREMTGLTAPNPAARSLFEVAWQAEENAPAGQVADWALLTGDGGLADEL
AARSGLVAYPDVAAVLAAVETGAATPAALVLPSRTVLGPAGVGVPESVRSVTSDVLSVVR
SWLAADALAGSRLVVVTRGAVVARDGDEVTDLAGAAVWGLLRSAQSEHPGRIVLADVDGD
VEPALLTTLAGAAAAGGQVAVRAGRVFVPRLVRASASGSSLVVGEGAVLVTGGTGALGAL
VAEHLVRAHGVRSLVLVSRRGPDAVGAVELVDRLAGLGAAARVVACDVTDREQVFGLVAD
VVSAGRLAGVVHTAGVLDDGVVEGLSAERLAGVLAPKVSAGWWLHEATAGLDLDLFVLFS
SIAGVLGSPGQAAYAAGNAFLDALAVYRRRAGLPAVSLAWGMWDTAGMAASVGDVDRARS
ARSGLPPMSAETGLELFDAALAVGRPVLVPVVVDVPALRSAVAGGVVPPMLRALVGTTTT
RRQAGQGGDGWAGRLAGLTEDEGRAQVALLVRGLVAQVLGHGGAESVPAERAFRELGFDS
LTAVDLRNRLNAATGLRLASTLVFDYPTPAVLADHLWSELAGVRQSTAQPTASTVAGLDE
PIAIVGMACRYPGGVESPDQLWELLAGGGDGIGEFPADRGWDLESLFDPDPTNSGTSYTR
HGGFLYGAGEFDPAFFGISPREALAMDPQQRLLLEASWETFESAGVDPQRVRGSRTGVFA
GVMYHDYASRLMDVPGEVEGYVGTGTSGSVLSGRVAYTFGLEGPAVTVDTACSSSLVALH
LAAQALRSGECDLALAGGVTVMATPGTFIEFSRQRGLSQDGRCKSFAASADGTGWSEGVG
VLLVQRLSDAQREGRKILAVVRGTAVNQDGASNGLTAPNGPSQQRVIRQALANARLSSQQ
VDVVEAHGTGTTLGDPIEAQALLATYGQDRPADRPLWLGSVKSNIGHTQAAAGVAGVIKM
IMAMRHGVVPATLHVDEPSPHIDWSAGSVALATEAMAWPVVNRPRRAAVSSFGISGTNAH
VVIEQPPAPVVVGEVVGRVVPPVVPVVLSARTDGALAGQAGRWVRWLSADEAVRPVDVAW
SSITTRPALEQRAVLLTNDRDDLLSALRALDRGEPSGAVVTGAATGRGRLALLFSGQGAQ
RAGMGRELSEAFPVFAAALDEVCAELDGRLPRPLREVLNAAPGSEAAGLLDQTVFTQAGL
FAVEVALFRLVESFGIVPDFVGGHSIGEITAAYVAGVLSLAEACALVAARGRLMQALPTG
GGMLAVAADEAAVVESIAGLADRVGVAAVNGPSSVVVSGAVDALDEVEQLWQGRGVRTRR
LTVSHAFHSPLMEPMLDEFRTVLAELTFSAPLLPVVSNLTGTLADGDEIRTADYWVRHVR
EAVRFADGITALRAVGVDTFLEVGPQSVLTAMAADVLPADDGVLAVAVQRRDRPEAHALL
AALAELHVHGVPVTWTQWFADAGAQRVDLPTYAFQHQRYWPEAPARQHTVPDGGDADFWA
AVERGDLTALATQLGDDAAVDALTPALPVLSEWRRARTRDTALDGWSYRIGWEPVRPAPA
TGLSGRWLVVTVGGGADAGVAQTLTEAGAHVDTLTVPPTQTRTELAERLRRIGAEGWAGV
LCVLPRQDRPLPHAPGVPAGTAALLTLTQALTDTGLPGRVWALSRAALPVSAAERVGDVW
AGLAWGLGRAVALEQPDRWGGLVDLPARADRSTRAALVAVLADGTLDQVAVRRNGVFARR
LVPAAPPTGPGWQPSGTVLVTGGTGALGRHTARWLLANGAAEVVLASRRGPAAPGAAALV
ADLADLGTVRVVACDVADAEAVTALVGGLPELTAVVHTAGASGGTTPAYGLTDGELSATL
AGKVLGAVHLDTACWGRDLDAFVVFSSVAGVWGGGGQAGYAAGNALLDTLVAARRAAGLP
ATALAYGPWASDGMAAGETADGLRRRGFVPLAPEAAVAALGRWVNAPEAAPVIADVDWSR
FVAAFTAARPSGLFDRVAPAGPAQPDPQPEDTGVTTALRSRLAGLPANGQETLLVDLVRA
EAAAVLGHGSTDQVPAGRAFRELGFDSLAAVQLRDRLGRVTGLTLPSTVVFDHPSALELA
RFLRTGLVAGAADGPAAGGTVVRPAADEPIAVVSMACRFPGGVSSPQELWRLLADGTDAV
TPMPTDRGWDLDSLFDSDPERVGTSYTCSGGFLADVAGFDAAFFGINPREALAMDPQQRL
LLHTTWEVFESAGIDPQRVRGTATGVFMGTNGQDYATLLLGARSQVEGYQATGNGASVVS
GRLAYSFGLHGPAVTVDTACSSALVALHLAAQALRSGECDLALAGGVTVMSTPGAFLEFS
RQRGLAEDGRVKAFAAGADGTGWGEGVGVLLLQRLSDAQRDGNRILAVVRGSAVNQDGAS
NGLTAPNGPAQQRVIRHALDVAGLTPGDVDAVEAHGTGTTLGDPIEAQALLATYGHQRPA
DRPLWLGSVKSNIGHTQAAAGAASLIKMVLALQHELLPATLHVDAPTPHVDWSSGALALL
TEARPWTGTDRPRRAGVSSFGISGTNAHVILEEAPAPRPAAGPGREADPAAADGHPVDPA
PAADRSADPAGLRDQAGRSADPTSVPWLLSGADLAGLRGQAGRLADLVAAGAGDPARIAW
GLAVGRAHLGHRAVVVAADGPTRSAALRALAAGEPHPALTTARRRSGGLAVLFSGQGAQR
AGMGRDLYAAFGVFAAALDEVCGHLDALLPQPLKPVLFAEEGTAEAGLLDQTVFTQAGLF
AVEVALFRLVESFGVVPGQVAGHSIGEIAAAHVAGVLSLADACAMVAARGRLMQALPDGG
GMLAVNASEAEVLPTLDGFTDRVGVAAVNGPTSVVVSGAVDALDEIERAWRDRGVRTRRL
TVSHAFHSPLMEPMLAEFRAVLAGLTFAAPILPVVSNLTGALAEGDELRTPEYWVRHVRE
AVRFADGVSALRAAGADTFLELGPQGVLTALTAGLLPTDSDGTAVAALRAGADEPAALLA
ALAALHAGGRDVDWSAVLDPLAGPRPTPRDLPDLPTYAFQPQRYWPTLTVAPAPAADPVD
DEFWRAVTDGDLGRLGIDPDQPLRQVLPELDSWRRRQHRDGTLDGWRYRVTWRRRPMTVG
NPGTWLVVTPRQQDPGGIVAALTAAGATVHVLPVDPATVTRDALAADLDRLGAEHGPTGL
LSLLALDDAPHPEQTALPTGLAANLLLVQAHTLRPGPAVPLWLATTGAVAVDDEPVARPT
QATTWGLGLVAALEHPRHLGGVVDLPGSPDEAAYAALVTALTNVEGEDQLAVRGTEVHTR
RLVRDTTRPADTGRGYTPHGTVVLTGGAGELARHAGAWLARQGAEVLPLEEPAAGKLTDL
MEQLAAESRPVTGLVHVPAETGSVPLAELTVAALAADLVVTVGDVPRYADELAHRPVDAF
VLCTSTSGVWGSGGRAGQAAGDALLHALAANRRHAGLPATDVAWGPWQDDPASPELEQLR
RRGLPGLPPELAVEALARAVRDEATVVVADVRWERFVPTFAAMRPCPLLTEIPEAREALP
ADDVRQPADDEAVAALRERLRPLGAGEHEVILVDLVCAQASSVLGHADGGGLEPDRAFRE
VGFDSMTAVELRNRLRAASGVQLPPSVVFDYPTPMALARHLRDQLVDDGTATAAPLLAEL
ERLDAVFAADTPDRLTRQKLLVQLQAFVARWGDDRPPVEEKPVTQTLDDATDAEIFDFIR
RELGGPGGDEPFGATR
>A0A086JYV0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii GAB2-2007-GAL-DOM2|TrEMBL
IEQVYLPKVTGAWNLHEVCESMGLDKNLDMFVMFSSVAALLGNFGQANYSAANACLDALA
EYRRARGLCAQSIQWGPWIEQGMAADLKALAEKAGLRGISNELGIRVLVEAVRNSKTVVT
FLAQSFIWKRFVQRFDVVPPFFSNIEFETASPGAFRVLYSSMTPDELHTYVSNVVLDTAR
QVLGTSELPALDSPLQELGIDSLGAVELRNSLSQRLGVKLSATTLFDYPTIRAIIDYIVN
QVSGEASAAKATSGALVSAGLAAGRNSPIAVVGYSCRLPQGSETPDKLWEMLRRAQDCVV
EVPLTRFDVDMFYDSDIDAKGKMYVRKACFMDDADMFDNSFFNISAAEVTYMDPQQRVML
EVAYDAFYSAAYSREHLIGKNYGVWIGCCNSDWHFLEQQSNPDKSSSYSGPGGSGCLVSN
RLSYVFGLKGPSMTIDTACSSSLVAADCGAQAMRFGYCDGALIGGVNLMLSPQLFLAFCK
ARMLSPDCRCATFDEKANGYVRGEGAGAIMLRHLADAQREGKRILGIVRGTAVNHDGRSA
SLTAPNGPAQQDVIRSALQIGGVDPLDVALVESHGTGTALGDPIEMGAIKAVYGAGRSAD
SPLVVGALKSYIGHLEGSSGIAGILKVLLCLRHHEVPPNLHFDTPNPHMDLSDFHVVLPK
KQMKLQPAQKSSTILGSVSSFGFGGANAHVVFEEYPEPTMATDVGGERRSTEAAESAGKK
RLAFLFTGQGSQYPNMCKQLYEEEPVFRSHMDACFTVLEGKLDVKLRDVIYPTAENDVEM
LNLLNQTGYSQPAIFCVEYALAQLMISKGFSPSVVMGHSLGEYAAAAIAGVMDWKDALLL
VHERASIMQHIDPNDGVMYACRASEQDAQAAVEKALGEKAVAVTVSAINGPRSIVLAGTQ
PDVLAVLKAMDMQSRAKQLTVSHAFHCPLVGEAAALLLPKVESVKLSNPNEGITFISTVT
GKAVGAGELTKPEYWATHITKPVQFLQGMRAAVTSGEAGIFIEIGPRPTLVNMGQQCVPR
NDYTWVAPVDPKDSNRNSFPQALEKITSNMVCTYTWKRHAFPWTVVVHPFVDKFVPDQDE
TKATSQKLLTPAVGELLHDHVVNGTAMMPGVGFLEAMAAGGFMMVDGKLPSTVVALRDCE
FERPMLIPKIDPSTGEFTQAAKLMITVNNKDITLKSIMDGEEEEIFHSRCTFSLCPATSL
PTEPADLLTSLQGRITTPVPITTLYETLQSVGLQYGARFQSIRECYAAASDEVLAKLRPK
LPLHSFERNFRIHPVLLDGALQTAAVLFAEMGHKRPLVPVGVKRALLARVPAGSEVWSHV
VVKSKDLRSATMDVTLFSTKGTILGQLVDVAVRAFDAVAGAQIPKGLLWEVSWVPKAKAP
VEDGVDTVENEASETITPTAKLAVKPTGKVEGLARQPAVNGQPKWLLLKTPSSMLEGLQK
ALQGTPSAFVKELDEKHPNNAISSKIHNSEWDAIIYLGALSAAASSTTCVADALLLANTL
GNTAAEKPLPNVLFVTQGQHFIRECGDVPTTAVPTQTGLYGFCRSAQLELENIIGRPVYL
GTLDFAAKDPTLDDPAAFVSALQRVLAEADPTGAAGTCEPHTVIRGGKEMVPRLVKSSIE
CRGAVELHMSDRGALSMLKLRPMPKSARVPPPRDCVEIRVRAVGLNFRDVLNVMGLYPGD
PGPPGADCAGTVVAVGEGVEHLRVGDAVFGIAQGALKTFVTTSAHLVRPLPGRLTFEQAA
ALPVVASTVEYALHDVAKVKKGDKVLIHAVTGGVGLAAVQFCKRVGAEIYGTCSGGKKEE
FARSVGVKYITSSRDPKKFAEDMCEFLGNGKHKIDVVLNCLIENYIPETLKFLAPNGRFV
ELGKRGIWTREQMGTVRPDVLYETVAIDTMMEEDPVWFGGMLDRIRNLVDGSMLQPLPLH
TFEMTDSSEGGVAAFRFLQRAQHIGKVVIRLSSALEVKNFTTNSRQETENEDSGERHTLS
PATAVGKPLSQSVADQMHKTYIITGGTGGLGLVVAQWLIEEGAHNIVLLSRRGEPPSSVK
AGDPVWKYLCGEEQPNCISVATLKCDVSQKDDLLRVFKEIESRGLPPVAGIFHAAGVTAD
AALASQTADSVDQVYLPKAIGAWNLHDACEALGLNKSLEVFMMFSSVAALLGNFGQANYS
AANACLDALAMYRQSLGLCGQSIQWGPWIEQGMAAQLTQHLEKVGMRGITNELGLRVLGD
VMMHPTVAVVGAQSLQWRKFLRRYAFEMPSFFSLVPMAGAGSSEASVNLATITKEDLCEL
ISSLAQAVSGAAEKPAVDTPLMDLGLDSLGAVEFRNSVADKVGVKLPQNLMFENPSISSI
SDYILDKAAGKHGESGVTGANGGSGEGSDIPALDTPLDQWLMSVLEPAERFALYIDSFAS
EYGTLQKMAAEEDIITALEDLGVEDGGDFERLHVAWDDLCNQINTAKRMAAKDIRPSSTA
VSVSDHPKPRMPHPMEDVDTLLASLDFDVSTLRPATAPDKVKNVLLTGVTGFVGRVQLAS
LMQLKQRPDLRVYCLVRARNADHALSRIREATKEAKCWQETFVSRIVPVTGDFTQPLLGL
SSEEFQELARKIDIVYHTGGDVNLLSNYGRLRATNVLSVKAIIDLCTTYKVKPLHFASTL
GQFPAFFAMFTGHFSGESIREDSTPDVSQMENFYPPSRQGYPWSKWAAERVLEGARKRGL
PVAIYRLPNTYVAYKTGYTNKTDYATALMIASIQEGVFPIGAATAPLTPVDTICDMLVEA
SFLEKPKHWVYHLFDPRLVTRADLEQWSQELGISYVGVKVDEFLEAIKKRGPESPVFKFV
PLMQHWRRFWFDPEERTESFPISNEHIFEDLPHMRWPSLREVFKNSLLYSVRMGFFPKNS
KSIILDPQVALNEARRICGLQLMGREGEDFFLHPWRVLQESARRECDLLFGGQLAVYRTV
RHYFMNVMYLADAQAKCPEIEKQEIQAPLIIVGLNRTGTTFLQNLMSTDPSNRSLRYCEM
IAPYGPDGNYRPKGLPNTEESWKKDPRIPFAQEILDSQLGLSEEWMAIHTQRAELPEEDF
VIFEHCGRCYSICTEFSVPSYREWLASDNYKETRKAYSFHKRFLQHLQWQRPAKRWLLKM
PFHLFTLEALFETYPDAKIIFMHRDPKETMGSWASLVKHAQQSLMDNVDPSALGREELRA
MSTMINRALAFRRSHPELGPRFLDVQYQDLVNNPIGVVKSIYKHFGIPLTLAAQTGIASF
CNENRKHRDKLTKHMYSLKDVDLTDGMVQEAFKEYYDSGLCKYLSSAR
>K9QFT7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc sp. PCC 7107|TrEMBL
MLTSHSRPWQLLVISAPTESELKTATVNLADYLRQHRDLNLGDIAQKLQREQQAFKYRRM
VICRDIEDAIVALTDPRRILTNIQETQKRPIAFMFPGIGTQYVNMALELYQVETVFRTCV
DYCCEFLKPLLGQDLREVIYPLGQPEQQLVPDNSQGLDLRKMLGRSQIATDTKILAATSL
LNQTHLTQPAIFVIEYALAQLLISWGICPTAMIGYSIGEYVAATIAEVLSLDEGLKLIAA
RAQMIQKLPRGAMLAVPLSPTEISPLLNDKLSLSAVNGSSMGVIAGESEAIEVLEQQLTK
KGLACRRLETSHAFHSHLMKGASSELRKLVSTFNLQAPKIRYISNVTGTWITATEATNPD
YWVKHLCQAVLFAPGIQELWKQQYPILLEVGTGQTLGSFAMQCLENNPAVSQLILPSLRY
SYDQKPDLGFLLKTLGRLWLAGVQIDWVGFYTQESRPSISLSV
>K9QFU2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc sp. PCC 7107|TrEMBL
MNENYELMEGVAIIGMAGRFPGAIDIECFWQNLQDGVESLSLFTDDELIAAGIPAALVND
SNYVKVGGILDNIDLFDTAFFDLNPKEAAVTDPQHRLFLECAWSALENAGYDATKCNSRI
GVYAGASLNNYLYFDVKNDQLGSGESYQKLIGNDKGFLSTRVSYKLNLTGPSLTVQTACS
TSLVATTLAYQSLQNYQCDIALAGGVSIRLPQKAGYFYEPGGPLSPDGHCYAFDAKAQGT
TVGNGVGVVVLKRVKDAIADGDCIYAVIKGAAINNDGAMKVGYTAPSVDGQAEAIAEAIM
LAEVEPETISYIEAHGSGTALGDPIEIAALTKVFRASTEKKNFCAIGSVKTNIGHLDAAA
GVAGLIKTALALKYQLIPPSLNFEQPNPEIDFANSPFYVNTKLREWQTNLTPRRAGVSSL
GMGGTNVHLVLEEAPTLPASSASRPWQLLLLSAKTASALATATQNLSQHLTLHPNLNIAD
VAYTLQVGRRDFNYRRILVCADVQDAILQLNQPVSQHQFQESGTPSVTFIFPGIDALYTD
MGKELYETESVFRTHIEKCCLILRPHLELDLRSVIYPSISERETALEKLQQTSFSHSALF
VIKYALAQLWMSWGISPQALIGQGVGEYVAATLAGVFSLEDALVLVTKSSPQLLEKIQLH
PPQIPFISHVTGTWIAPTEATNPHYWTDIEAALYPEIAELLQGKQQILLEINLQEPLANH
RQQHSETAFLLNELGRLWMLGIKIDWSSFYTNELRYRLPLPTYPFERQRYWLDSINTQES
LEPISNYFLENQRYAIELDSSTSKKYSRKLLEKKTNIAEWFYTPVWKQSRLLDFLPEELS
QKQLNCLVFVDKYGVGSEFSKQLAQQHQDVITVRLGEQFSQLDEKVYCINPQQPDDYDLL
LKALQQRDFQLNTIAHFWSVTPKYISLDNEYDNLSFYSLLFLAQAIGKQDIWDSLKLMVV
TSNLYDVTGEENLCPHKATVLGPCKVIPKEYRHINCSLVDLIIPAAQTPLSAKNLDKLIA
ELTLEQTNEIVAYRGSHRWVQTFDVVPLEDSGVSKNKLRKGGIYLITGGLGGIGLVLAEH
LAKTFQSKLILVSRKGLPERSQWEQWLENHDSQDAMSRQIQKVRSLEELGAEIEVISADV
TNLAQMQAVIAQALQKFGQIHGVIHAAGVPGGGVTQLKTRDMADHVLAAKVQGTLILEEV
LKDINLDFLVLCSSKTSILGEFGQIDYCAANAFLDAYAYRNCISDRFTVSISWDTWQEVG
FAVETVLPDKLQQERAEIIKKGILPSEGIEVFNRILASNLPHVVVSTQDLPELIKQNNSP
QYLQEQLQLLDSKLSSVNLAKAKHPRPNLGNDYIPPETEIEQILAEIWQEILGIEKIGIY
DNFFELGGNSINTIQIAAKANQAGLQLTSQQFFHYQTIAELATDLAITPTIPDTKSQPNN
NQSDVNNSQQSLLLQIQRVCDDPNLLENIADIYELTPVQKGMLFHCLFDSELSLYFFQHL
FTIRGDLNIEAFEKAWQLVIDRHPILRTRFYWEELENPLQIVYKKVELPLSCCDWSNINS
AEQKSQLDAFIVSDRQKSFDFSQPCLMRHTLIRCTDDKHLYVWSFNHIIIDGWGGSLVFQ
EFVETYGTLCQGKETIFAPTRPFREYIDWLQQQDITKAENFWRQALQGVKIPTPLTYIEK
LDKIEPSSTQEVRYSEEIIQLSAKTTQALQSFATQHRLTLATIINGIWAVLLSRYTCCNN
ILYGCTVTGRPADLPGVESMVGMFVNTLPIHVNIDTEQLFLSWLQRFQLQLVEVRDYEYS
QLTEIHKWSEIPQKLALFESIVVVENFPVSEFIRDWQGNIEFQHTQIYYRNNYPLNLVVY
PNKELLLAISYDSRRFATTTITGILQDIEMLLQGLVTNPHFQIKNLPLGTPEQQQNSAIL
EQEISFDWSSVL
>A0A2P7Z5B8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. 111WW2|TrEMBL
MAGADQVLFTSRLSAHGHPWLAEQAVFDAPVLPVSALVELALRAGDELGVPGGLAELDLR
TPVVLPEQGFMQLQLGVGPADDAGRRPFTVHSRPDDADAPWKVHAHGAFESADGGAPLPG
PSSDANATDVRLAEELLPDAARYELHPALLEAAVMAAAGTGEAGTTPVPAHWRGVRLHAS
GATAVQVRVGAPDEHGVSVLLSDAEGQPVATVERLTFRNVPDAEFAVDSEGSRPLFRVDW
DRTALPEPASPVRWGVLGDGVRFDGPADGIMAFEDVAAVGKAAEAAGTGAPVDAVLARIT
PEGTGGAPTAAHAAARGALNLVQDWLADDRLATTRLVVATRGAVHAGGEQDAPDVGAATV
WGLLRSAQAEAPDRIVLVDLDHADEGTEPSVSSAPLSALVASGEPQAALRGGETLLPRLR
RLPARASDGSPAEPVWDPEGTVVVTGGTGALGSLFARHLVARHGVRHLLLLSRRGEDAPG
AGELMADLAALGARVTVRAVDVADREALAAALATVPDGHPLTGVVHAAGILDNGLVSAQT
PESLAAVLRPKADAAWHLHELTKDVDLSAFVLFSSSVGVVGGPGQSNYAAANAFLDALAE
HRTRLGLPAKSLAWGLWDLGHGINAGLDANDLKRFTREGFRQVSPEAGTALFDAALDGSA
ATVVALPADLSAMRAHGRVPAVFGALVRVANRRTAQSGTVAAESFAQRLAGLSVPERRQA
ALDLVRAEVAAALGHSGPDAVPAERAFQEMGFDSMTAVELRNRLIAASGARLAAAVVFDH
PTPEALAEHLLGEVAPEAAGDPAQPLLSELDRLEASLSALAGDGRARSAVSVRLQTILSR
LNEAAGPDESSDVVSSLDSASADDLFDFIDNQLGRSAN
>X8B9K2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacterium avium subsp. avium 2285|TrEMBL
MSELQTLLTQPGLSPGDRAQLVTRLQSLLSTPPQPSGHPEFPEDAFDDDIATATDSQLFA
ILDDEAGP
>A0A2P8AQD5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MH33|TrEMBL
MPGFVAVRPSPLLTGVPAARRAAAERAEDTGASAESLAALLAGQTEAERRKTLLELVRGQ
AAAVLGHASTDAVEPDRAFRELGFDSLTAVELRNRLTAATGTRLPATVVFDYPTAAALAE
YVRAAVVDGGVVGAAPVFGELDRLEAALAGSAPDRSARNRITERLRALLASLNEADAPAD
GDAVAEKLQDATPDEVFDFIDRELGVS
>A0A2P8ANP6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Micromonospora sp. MH33|TrEMBL
MLGHRTADAVPADRAFQRQGFDSLTAVELRNRLAAETGLALPATLVFDQPTPLALAAHLA
AALTGAPAAEDRPEAAAAVDDDPIVIVGMACRLPGGVTGPDELWELLAAGRDGISDFPLD
RGWDSFLTGRLSDASFPRQGGFVYDAGEFDADFFGISPREALAMDPQQRLLLEVSWEAVE
SAGIDPARLTGERVGVFAGASFQGYASTAMGRDQEVGGHLLTGTATSVLSGRVAYAFGFE
GPAVTVDTACSSSLVALHLAAQSLRSGECTLALAGGVTVMASPATFVEFSRQGGLAPDGR
CRSFADSADGTGWGEGVGMLLVQRLSDARRDGRRILAVLRGSAVNSDGASNGLTAPNGPA
QQRVIRAALAAARLSPADVDVVEAHGTGTTLGDPIEAQALLATYGQGRDGQEALLLGSIK
SNLGHTQAAAGVAGVIKTVLALRHGLVPATLHVDTPSSKVDWSSGAVRLVTEARPWPAVA
RPRRAAVSSFGISGTNAHVIIEQPEPEPAARDALPAGAGAGGGRSADAGASGRPVLPWLV
SARSADALAGQARRLADHLRGSGSASPVDLAWSLATGRAALEHRAVVLGTTVDDFAAGLA
ALTGGATDPGLITGAVTTGRRALLFTGQGAQRPGMGRDLYGRLPVFAEAFDRVCALFDGR
LDRPLREVVFAEPGSDLAVLLDQTVYTQAGLFAVEVALHELLSSWGVTADYLAGHSIGEV
TAAHVAGVLSLEDACALVAARGSLMQALPAGGGMLAVAASEERVRNLLAADRDGTTVPAD
VAAIPVDGATVPVEVAAVPIGGAAVAVDVAAVNGPRSVVLSGPVVELDRVAGECAERGWR
VKRLPVSHAFHSRLMEPMLADFRAVLEGLDWRPPRLPVVSNLTGQLADPAEIAGPEYWVR
HVREAVRFADGIATLHTLGVTTLLEVGPDATLTAMAAETTADGPVHHIPALRRDQPDTTA
LTTALARLHVTGAPVDWTAWFTATGQQPQTVDLPTYQFQHQRYWLHEDATPVTPLNGGDS
GTDDRFWAAVERADLSALDPALRLDQPASALLPALARWRRDGRRRATADGWRYRIDWQPV
PDGDAATLAGTWALLVPYTGIDDGVLAAVTDGMTAAGADVRPVRLDGPADDRELVAKALR
DVGGAAGVVSLLALGGAGVGEALATVQALDGAGGRLWWLTRGAVAVGASDAPVDPPAAAT
WGLGRVAALEEPRCWGGLVDLPEMVDARAVGRVCGVLASGVEDQVAVRSSGVFARRLVPA
SSDPVRRGFRLSGTVLVTGGTGALGARVAEWAAGAGAEHLVLTSRRGGDAPGAGELADHL
RGCGVRVTVVACDVADRAALAGLLDGLAAQGDPVRSVVHAAGAAQATPLAEMTGTELADV
LRAKVDGAAHLDELLPDGLDAFVVFSSIAGVWGSAGQAGYAAANAYLDGLVARRRARGVA
GTAVAWGPWAGAGMAHGEQQDQLARRGLPALDPDWPSPPCRARSTATTPRWSSPTSPGTG
SPPPSPRCAPAHCSTASPRQRWTGRTPRRRTRAPRGRCATGSPPPGRPSGTGSCSTWYAA
PPPRCSDTAARPRSGPAAASSTSASTRSPPSSCATGSPPRPAWPCPPPGLPPHAGRTRRA
PARRAAARRPGRSGRRRDRPARPAARRGARGPARGRGDHPPARGAAGPLARRRGAAAGRR
RRGRRRPGRRRRGRHLRHHPAGVRQIVTSSRPRGPHAARGGQLLAISDLHVMYAENRPLV
EALRPDSDDDWLLVAGDVGEYVHDVEWALGLLARRFARVVWAPGNHELWTPPDDPVQLRG
EARYRHLVALCRRLGVVTPEDPYPVWDPDGDPLLIVPLFVGYDHSWRPPGTYNRAQALAL
AHETGIVCTDEILLHPDPYPSRDAWCRARVIRTERRLDAERGELPTVLVNHYPLVREPTR
ILRYPEFAQWCGTDLTADWHLHYAARVAVYGHLHIPRTTWYDGVRFEEVSVGYPREWRRR
ATPPGRPRVILPALARQHS
>K9ZJP7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Anabaena cylindrica (strain ATCC 27899 / PCC 7122)|TrEMBL
MSIQQDMTAKMAIVGMDAFFGECGDLDAFESSIYDGKQHFIPLPEKRWHGINEQEKLLQK
YGLEAGKAPQGAYISDFEIDTLAYKIPPNEVEKINPQQLLLLKVCDRALKDAKISPGANV
AVIIAADTELSVHQLQQRWNSSWQLKDGLNSLEIAVSPEKITELETILKDSIHPQVDLGE
IISYVGNIMASRISSLWNFSGPSFTISAVETAAFKALELAEMLLATNEVEAVVIGGIDLA
GGVENVLLRSQLGKLNTGINTLSFDEKADGWNVGEGAGAVVIQRHDTALQNNQRIYAVIN
GISIGQSSSMAIDSATITQVCKQAFQQAGIQPTEVNYLEVCGSGIPTEDEAEINGILQAY
PPVGDGLHCAIGSVKANIGHTFVASGIASLIKTALSLYHRYIPGTPNWSGVKTPQVWEGS
PFYVATESRPWFSQKEVKCRISAINSIGCDGSFAHVILSEETQQTERSSRYLESRPFHLL
PIAANDQSSLFAALDNLQQTIENADSLKDVASQTFVEFQQHTEAKYTLSLTGRNQKELLK
EINSAKKGVTNAFENGKDWQTPIGSYFTPKPLGKDGEIAYIYPAAVNSYLGIGRSLFRLF
PKAFDDVIVKSLYERAADVEKLVFPRSLSKLSTRQLETLEKKLFDDSLAMFEAEVLFTRL
ISTIITDDFQIKPKYIFGYSLGETSMMVAQGVWSNFYEVSNTFNSSALFGDRLSGPKNAV
REYWGLPKASITSDDNFWSNYVLMATPAQVRECLKNEPRVYLTQINTSEEVLIAGEPVAC
ERVIKTLGCNAFPAPFDHVIHCQAMESESQELEKLYTLPAQTIPGITFYSAAEYQPTTLN
SQEIAHNIAKGLCQQLDFPRLVNRVYADGAKIFIEAGAGGICSRWIDKNLSNQEHITVSL
NRRGIDDHSSLVKALAKLLSHGVHLDLSPLYNLSSVTGKQNKSTLRKITLGGNSITAAIL
NEDNRKLFQKATQIKQQQIISNYPEYKIINSLQPPAKFAPSDIYSHPEKNTMKTIMDNGL
KTREQLQSSELTSSQKPNIPSTLTPPLITQETSNTISMNDLKLSQYQKLSANNSKLTQAH
TSFLHARQDFSQQMSEIIQLQLACAQTLLSEEK
>A0A379N698|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Roseomonas gilardii subsp. rosea|TrEMBL
MPVAKNSQKNRVKNPQRKVVPIAIVGAACRFPGAPDLEAFWRLMAEGRDAVSTLPEDRFS
QARFHHPRKGEPGRAYTFAAGHLGDIAGFDAHAFGLSPREAAEADPQQRLLLEVAAEAIE
DSGLPASTLAGRPVGVWIGGSSTDYAELRLSDPSGADRYFMTGNTLSILANRLTNVFDLR
GPAQTVDTACSSALVALHHALRALAHGDAEMALVGGVQLLLSPYAFMGFSRASMLSPTGR
CRAFDAAADGYVRAEGAGVVVLKPLDRALAEGDRVRAVLLASGVNSAGRTIGLSLPNGEA
QAALMARVMREAGVEPEQFGYFEAHGTGTQAGDPIETWAIGEAIARRRRAPLPVGSVKTN
IGHTEPASGMAGLLKAMLVLERRSIPPSLHFSTPNPNIAFDRLNLHVPVAEEPLRLGGRP
ARRRGDPAPVVGVNSFGFGGTNASVILAAAPVAATEEPGPGEVPAPAAAPLPPLLLSARS
PAALGLLAGRWRARLAETPDEDLPALLRGAARHRDLQPHRLALRGRGAAELAAALADWSE
GRDSPAATEGQAPAASGLPAGGLAFVFSGNGSQFPGMAREALAASPALRAGLEEADAALA
PLLGWSPAARLAAGVSEAEAAGTDIAQPLLFAIQAALLRALAGEGLRPALVLGHSVGEAA
AALAAGILDMDQAARLVVARSAAQHRTRGQGRMAALALPPEEAAPLLAEAGPGLEIAARN
APRAVTVAGPAGAIARLAELAKARRANCVPLDLDYAFHSAAMEPVRETLLGALGTMAPRH
GTIPFISTVTGAPLPGEAADAEYWWRNLRAPVRFAEATAAALGQGARLFLEIGPNPVLQS
YLREGARAAGLSAGVIFSLSRRDRPEAFPGGDPIPAIADRATTRGADPRGGTLFQGPARR
DLPLTPFARERHWLAMTAESERLHDAPRDHRLLGERRDPEPRLWSRELDTLLEPWLADHR
LGGEPVLPGAAMLEMALAAAALRFPEAPALEVATFQILRPLPLSDSEARQVRLRLADDGI
VTLESRLRLAETAWTLHARGRLGEAGEAALPDAPALALAAPDEMTGAEITALAARLRLDY
GPAFRPVAALASEDGQAVLRLALPEAAPPDEGFHLHPVRLDGALQGLIGLLAPQFPVRAE
ALPEGEALVPVRFERLVFRRGAAPAESAELRLASLGERSAEATLLLRDAAGRAVAFAQGV
TLQRLRLARGEEAPLRAFRLEDVPVADPSLPAPEPALAAALAAAMRADERLDLSESALLL
EGWAGALAQRALSALPAARPLAPAAPLANGLWQALAEDGLARHDGTGWRLLPQEELPAPE
EIWQSVLAEQPSLAHDLAWLALAAEHLPGSLAGHVPALPLAPPDLAGGQDRLAEAAAAAA
AALAAAWPADRPLRVLDLGGGALTRHLLAALAETGRAVTLLVAGEGRPLPEARGGVTPEP
LAWDPLSDQPAPVAADLVAGIGAALRARCGTGLLARLAPALAEGGTLLLAEPLPGRLFDL
ALGQEPGWWSGRPLPDAAEWRAALAPEAGWQHAQAEPLRAAPWPALLLLAARPAPCPSVA
GAVPGTARPLLLADAGAAALRDALAGEFAALPDALRDGGRLEDATTLPARELRGAELLVL
AAPEEAALPATLASLARLAEAAQGAVRRFTLVIAGGPAHPAAEALRAFARGLANEMPDLA
PRRILLDTALEPRAAAARLLPELLAPGAEPELLIGATARRAPRLRPGAADPRPPCAPARL
AVRQPGQLGTLAWEALPPARHPMPGQGLAQGEIAVRVEAAGLNFRDLMWAQGLLPEETLR
DGFAGPGLGMEFAGVVEAVGPGTALHPGARVFGFAPRALASHAVTRAEAVAPMPEGMGFA
AAATAPVAFLTALWSLEACARLQPGERVLVHGGAGAVGLAALQVARAAGAEVAMTAGTEA
KRAFLRAAGADLVLDSRDAGFADQLRRHWPEGVDVVLNSLAGEAMERSIALLRPWGRFVE
LGKRDYAEDRRIALRPFRRNISYFGVDVDQLPAARPAEAQRLIESLRDRLSRGELLPLPR
LTRRAEEVEDAFRLLQASAQIGKIVILPPRLQAEEKPDWTPPEGIVLVTGGTGGFGLECA
KWLAASGAGRLALISRRGPATPGIEAALVALGALGARASAHACDAADPQALAALLDTLRR
EGPIAGVVHAAAVFDDGALASLDAPRFAAVLAPKLGAALNLDRLTRRDPLELFLLFSSAT
TPLGNPGQGNYVAANAGLEALARARRAAGRPALAVGWGPIADAGILARESGTAATLARRL
GVEPMASREALDSLPALLSGDQPVVHLARLGWRRLGAALPVLREPAFALVREAGGTGAEV
GDMRAHLAALPPEEARALLVRIGAEELGRILRLPPESLAADTPVARLGLDSLGGLELRGA
LEQRLGLSVPLAGVTDDLTLGTLAARVVDGLRGGGEEAQVAMLLEHFEPSRPPEGMGGEP
APAPASRDDVRHGPLPAASRHDSPGGPHPGASGGQPLTTEGETAR
>A0A4P7CA51|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Saccharomonospora xinjiangensis|TrEMBL
MSTAPPPAPTGPAPATTGAHVWPVSGRTGEALSALAQRLADHVRARPGLRAEEVAHSLVT
GRAHGEHRAAVVGTGRDDLLAGLDALAARRPSDAVVSGLARPDGGVVLVFTGAGGQWRGM
GGGLWDDSPVFRDSVRACAEAFEPYVDWSLVDVVRGRRGAASMNRVDVVQPALFTMAVSL
AAVWRAFGVRPAAVVGHSQGEIAAAHVAGALSLQDAARVVALRSRLIAGALAGKGAMLSV
PLPATEVRQRLASWGDRIAVAAVNGPRTTSVAGEPAAIEEFFAELVDEGVRVARIVSDFA
SHSAQVDAIHSALIDALGPLRCEASDVLFCSTVTGGVLDTAELDAEYWYENLRRPVLFDS
AVRTLLRRGFGMFVEPSPHPLLVAPIEEIAAEVGARATAIGTLRMGESDAARLLASVAEA
HVHGTAVDLRQACRGGSRVGLPLDDVAEGSDAENRFWSAVRRGDLATALGVVLPALDTGA
G
>A0A445N4Y7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces netropsis|TrEMBL
MSTSREPGAGAPDPRLTKALTAIKDLRAKIDALEDARRAPLAVVGIGCRLPGGVTSAASF
WHLLENGVDGISEVPASRWDMDAFYDPDPETPGRTAVRYGGFLDDVDAFDPYFFGISPRE
AERMDPQQRLFLEVAWEALEDAGLTRKRLSGSATGVFVGTNCSDYLQMQLADPADIDTYT
VLGGLAFAIPNRLSYLLDLRGPSMAIDTACSSSLVAVHTAATSLRTGECDTAVVGGMNLI
LSPHAMVAHTKGLPIAADGRCKTFDARADGYVRGEGVCAVVLKRLPDAVAAGDRIWAVIR
GTAVNQDGLTNGLAAPNGRSQRDVIEQALANARLEPSQITLLEAHGTGTSLGDPIEVEAL
DSVYGRVDEDGDSCALGSVKTNVGHVEAGAGLVGMIKTALSVHHRRIIPNLHFETINPHL
SLDNSRLYIPTAPRDWDVPDERCHAAVSSFGAGGTNAHVILGPAPAARPVTTAAQDAATG
SGPWLIPVSAPTRRALAPMAAAYRDFLLSAPGRAVPLRDIAWSAAHRRTHHEHRCAVVAD
SHEEAAAQLTEWLEGRGGTGVVTGSTTSAVDRGVVFVFPGQGSPGAGTGSELMDTCPVFR
DTVTEADAALRRWTGRSVVEEIHGAGDAGDDRAEPRAKGIGQPALFAVGVGLAAHWRSLG
LEPDAVIGHSMGEVAAAYVAGVLSLDDAARIVCRRADLLGRIHGRGTMLAAALPRTEAEA
LLDGRRDRVSVAVCNSAVSTMFSGDPAALDEIAHELRARNVLCRPVGTDIAWHSPQTDPL
RADLLAALAGITPRTAKIPVLSGVTGRLCDGTGFDAAYWARQLREPVLFGDGVGTLLEGG
HGVFVEMSPHPTLLSAVEQVLEPAGKEGLLLPFSRSGEGERRAMTASLGALHAHGFPVPA
DAVFPAEGRAVALPSYAWQRERFWFRSGPRAGSTGPAPASSPTASPVPSPAPSPVPPPTA
GTRDRAPAGHDRDGVFTAVLDAVSDLLHLDRERVDPDSGFFQMGMDSLLATQVRRRVEAR
LGRKLPATVMFEHPTVNGLTDHLAEAAEAAEAAGTVAPDTPRRHHAAQESVEESVEGLSE
DRLLAILADEIRATGSTR
>A0A445NBT8|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces netropsis|TrEMBL
MSLDPVAVGAREAAGKGDGGPGDLGPGGDGGKLVFAFAGQGHQWAGMGRDLLRTEAVFRA
AVERCDAALAPHTGWSVVDRLTRDDAWPLMRRTDVLQPTLFTVQVALAALWRSWGVVPDA
VVGQSMGEVAAAHVAGALTLEDAATVQCRRGALLQRISGRGTMAVVELPAAEAAALIADT
GGKAVVAGYGSPTTTVLSGDHDSLDAVLARLAGTDVHARRIPGTAPSHSPCVDELRDDLR
TALSGVRPRRAAVPLYSTVTLRRIEGPELTASYWIDNLREPVRFAPAVRQLSCAGHGVFL
EISAHPVLTEPVRQCLEHAGHRGLALPSMRRNAELDALRASRDTLRTLGRPDPARARRPE
LTPYQAAVLPALFAR
>B8MBC1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MPIYTPTASSDSDDDSPKMELVYFSNEFPSEDLQNLFRQLHSHSKDKNHPVLACFLNEAT
WAVKDEVRRLPTELKQLISPFETILSWAEDTELREGLICGAVDGVLLTVVQLATYIGYAE
SYPEELCDLSNTYLAGLGIGLLASTAVSLSSTLATLPLAGADAVRLAFRLGIHVQGVSEN
LEARDLSEKPDTWAYVVHNVDSEAAQKELNVMHSRFETPETAKLFVSAVSRTSVTVSGPP
TRLKALFNKSEFFRGSRFIALPVYGGLCHAPHIFGHQDIWSIVHGSSLNSISRKAWPVVP
VYSTSTGLPYPAKTAGELFESVVAELLTHSIYWDRVILGLVDRVKCIGASEAVLHCFGNS
IPLNDLNTALKDGLPKTKVLINNLIPWMSEISPTGTTTRSPAQSKLAIIGMSCRIPGGAT
NTEKFWELLEKGLDVSRRIPPDRFDIDTHFDPTGKELNKSMTQYGCFIDEPGLFDAPFFN
MSPREAQVVDPQMRLALVTAYEALERAGYVGNRTASTQLQRIGTFYGQAADDYREVNQGQ
EVSTYYIPGGCRAFGPGRINYFFKFSGPSYSIDTACSSGLAAIEVACQALWNGQVDTAVT
GGVNVLTNPDGFTGLCNGHFLTKGHNACKTWDATADGYCRADGIGSVVIKRLEDAEADND
NILGVILGAGTNHSAEAVSITHPHAGHQAYLSRQVLRQSGVDPLDVSYIELHGTGTQAGD
YEEMKGVMEVYAPLTKRRGKDQPLHIGSVKANVGHGESVAGVTSLIKVLLMLQKNAIPPH
IGIKTEINPKFPRDFDQRNLKIPFEMTSWPQVPGKKRILAVNNFGAAGGNTTMILEEAPT
RDIEEKDLRRTHIIAVSAKTKGSLVGNIERLIAHLNAHPDINIADLGYTTTARRHHHSHR
IAVSTTDVNHLKKHLAASLEKTDSVKPVGKSGPPPVAFTFTGQGASYKSMNLDLYRDVPT
FRETIQHLDSLAQGQGFPSFIPAIDGSHPKDYVHSAVVTQLALVCTEIALAKYWATLGVK
PDVVMGHSLGEYAAMHVAGVVTANDTIFMVGRRAQMLEEQCKIGSHSMMAVRASLAQIAE
VSAGKPHTIACVNGPSDTVLSGAKDQMDEIAAILEAAGYRCIKLDVAFAFHSEQTDPILD
DFEAISKSGVIFQEPKLPVISPLLGRVVFDGKTLNANYVRRATREAVNFLAALENAQNVS
TVSNETVWIEIGPHPVCTGFVRSTIPSTQLTIPSLRRGENNWKTMSESMAALHLAGMDVS
WNELHRPFEGRLRLLDLPTYAWNDKTYWLQYNGDWCLTKGNTFYDSEKEVTKAKLISSAQ
VTSEVQTSTVQQIIEQDFNGSAGTVVMQSDVMQPDFLAAANGHRMNNCGVATSSIHADIA
YTLGGHLHHKLRPKTKEVHMNIINLHVTKGLVAQSNTKKPQLIRVTATTANIDLGIVDLT
WQNVDNAGNARESFATAQIIFGNASEWLSSWVPMAHFVQGRIETLEHMAATGQASRLSHS
MAYKLFASNLVDYADKYRGMQSVVMYGLEAFADVELTTKDGGVWTVPPYFIDSVAHLAGF
TMNCSDTMDTKNNYCVTPGWNSMRFAKPLLPGAKYRSYVKMIPTVEDPTVYFGDVYIMQD
NVIVGMVGGIQFRRYPRILLARFFSPPDKMPVMEAKAPVAKSSVSTPQPVTEAKHPSAAD
KSESLPSSVETIPAESKPVAKANVESAVSSNSITTKALALIAKEAALEISKLEDDASFSH
LGIDSLMSLVISEKFRTELDVKVSGSMFLDYPTIGDLRKWLEEYYS
>B8MPT9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006)|TrEMBL
MASQQVIFFGGQGGRSSGYAPSTITLKGNENSHCLTLLLSACHSIFLEEAFKARKGSNAP
AWARFDVFPSPERLLVLSPEESTNPILQGVSLCLNQLLTYLNYDCDLQNPEPVAIMGFCS
GMLPAVVVACSESLDEYIAYSKEAIRAAFWVGYRAAELSSNIGGRQWNELPWAMSVSGKT
REVLMEEIVIFNQTSKKTTAHEVIILANIFGEKGFSIVGPGYLLEQFRSRYHSENTAFAL
IPVHALYHAGENSASALEAVLTDLNTDRCAFPSRDKLKRPLWSCHNGGILNAAGPDQNSL
LQCILTCILVEQADLLTTWNNMVKEMELSNSSWSAITIGDGARALLSTVNKDVHSSSKHS
FIDLPRLPMNSNSGSCNEFAVVGMSVNFPSGLGKAQFWNMLELGLNAAQEIPGTRFCVDD
YQVGKGQHGSKREMKIQHGNFINNPFSFDHEFFNISPRESKSMDPQQKLLLQGAVSALDD
AGYVPYSTPSYNPETMACYVGIATEDYVQNLNSEIDVYYSTGTLRAFLSGKISYAFGWSG
PSVVIDTACSSSTVAILNACRALAAGDCSAALAGGANVITSPDMYIGLSRAHFLSSTGQC
RPFDAGADGYCRSEGCGLFVIKRLEDAVREHDRIYGVIKGIEINQSGNATSITHPHAETQ
QKLFQKVLTSSGIDPATISVVEAHGTGTQAGDGTEASSLMSVFGGLSSIQSVYLTSIKGN
IGHAEAASGAASLAKLLLMLQNRTIPPQVGLKRLNPKLERLMAQNFHISTQAIEWKPPRN
IPRRALLNNFGAAGSNATLIVEEYERRTPMKTRHEQRSTYMFILSAKTEQALRTLINRHK
EFLQKNDQYDSIANICYTVTARRRLYVWRLSLAVSSSKDLLKQLNDEHSINQCVESIGSP
VTFVFSGQGGFYAGMAKSLLSTSSLFRDKVTECDQILKLFNLPSVIPILEGLSSPDSKLD
FILWSQIASFVLEYAVAFLWLSWGVKPDLVIGHSLGEYAAMAFTEALSLKDSLGMIVRRA
QLMVELCQCGQSGMLACESSVSFIGKIFASDGFQNLSIACDNGPTSCVVSGPNQDLDRLA
QILRSQAVRCKSLDVAIGFHSDALEPIMKPLEEHCRDFVFHAPKFPMGSCLHGRLLDSSE
LEPSYIVQQTRGTVRFKRLLESLREARMNSGIFIEIGPHPITLPMINSMFRDDGCLSLAS
IAKNEDAWATLCSSLREISDRGIPIRWREVFDGTDATVTDVPEYPFKSHSHYIPFSEMRH
QTDDIAKQVISAKPNSFELLDSILYEMKSELNVPSKFSTELASLSKYILGHVVGEFPLCP
ASVYIECVLEAAHWDDKFNKEFVLTVHNIDFGLPLLYSEERLSNSIDLTFENGVPTYDQI
SETRITRRKFTFTQSVSSEPSHSPKKNSEALCSGWAEWENVKDIEYLFSRSSAYIRRQIA
HLQGRETNTNVFRPKALYQLVFPRVVSYGEEFQTIKELKVLEDGLEAHGTFKIPPISSKG
GILTPVFVDTLLHAAGFVANSYIQKTEACICAKVESIKVFYQDLDLHQTFQVYTSLLECN
NGVLLGEAYAVTLDGTVVGTVEGMHFKKLNLKSFKAHLSRQLLHDTPNQVSLQVKGNQQK
PNKQKDDDFVVTRKEPQPKQDMNVPKIVLETICQICERPLNSIRGSSTLLSLGIDSMMRI
ELGNLLAKKLTNVDLDMDHMTEIDTISQLQEYIIEKAAKSEPYTSSASDIAHDSSIGNSS
TPADTPFSGLSSQSQTPPVAEGLHDLYHIINQTCEIPLSKISPEIALESLGMDSLMAIEL
QEALQQHFGQSLPENNPVSNWTVQDLIIHLGLNKHEDYIKSLQDINQDTSFSMLAVTPVL
THLQNGDPSLPPLILFHDGSGTMEYYKKLKNIGSNVYAIMNPILKEDHWAKSLTDMAHQY
ASAISTTIEGPFILGGWSFGGVLSHAVAQCLERLDEKVLAVIMIDSPCPENLEPLPSAIV
KYVLGQKNLSYSTELVITAQFQKHAQFLAEYSSQRSATQGFIAKERKYFMIYCQDTLNTS
KICGVDHPWLSDKNCREQALNQWEQILGRSLTVLRIPGNHFQVFDSAYVDVVSQQLQQAY
TAAI
>A0A077NGC4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Xenorhabdus bovienii str. puntauvense|TrEMBL
MGNNFTGLEVAIIGMAGQFPGADNIRDYWEMLRDGKEGVSRFTNEILKSNGVSEEYYLNK
NYIPAKGVINKPFHFAADYFGINHSDAKKTDPQIRLMIESCWQALKHANIDTETYPGQIG
VYAGASSQWSWFKALNTEFNSSAEQFHVATLNDLSFCTRISYLLNLRGPSITIQTACSTS
LVAVHTACQALQAGECDVALAGGVSITHPHQSGYLYQEGMINSPDGKTRVFDANACGTVF
SNGVGVVVLKRLSDAIEDNDKIYAVIKGSAVNNDGSDKISFTAPSVLGQQNVIRSALDFA
EVTPDQISYIEAHGTGTLLGDPIEISALNAVFKNSQSCAIGSVKSNVGHCDAAAGILSLI
KSALCVYFKTLVPSIHFEKANPKLELENTPFYVNTETKPWHSSDNELICAGVSAFGVGGT
NAHVVLQEFPIRTETVSVEDLEYEELPNRIEFKPAIAAETTDVLHAEVESDSVFVDDEID
IEGLPQNLLKIFQEYFSNQKISQNDNFFDIGASSLDIVQLHEKINNTYSVNLSISDFYRY
TNCQKMTEKLLGMIGNKSQGQPKKSKITKKRKVLNNKNRTYQDYPEHAIAVVGMSGRFPG
SKNIQEYWNNLLQGKEGISFFTDDELIDAGISAHTLKAKNYIKAKGIVADSLSFDPTAFG
YTARESQYMDPQFRLLHEVTWQVLDDAGYGNPKYRPVTGLFASSGSNHAWLDLLKEEIQD
TTEQFGVALLNDREFLTTRIAYKLNLTGPAVTVQSACSSSALAITLACQSLQINQCDLAL
AGGVSVVTPIKSGYTYAKGMVNSADGHCRPFTQDASGTVFSDGIGMVALKRLDDAIRDND
HIYGVIAGYGVNNDGHEKAGFTAPNADGQAACVKQSLKMAAIQASDVEYLEAHGTATQVG
DEVELEGIKDALGVTEINARDCFIGSVKSNIGHTNTASGVASFIKTLLALKHQKIPPSCH
GTENKHTSLENTRFRLTDVAADWVSHGRVRTAGVSSFGIGGTNVHITVQSIEEQPASSQC
QAELITLSSKSREGLVKTMARLGDFLDEEQHSYSLSDIAYTLQVGRGDYDYRTSLVVENV
EALKDALHSLKDSNTLPEALPDQTSGIVFMFPGQGSQYVNMAKDLYQELEIFKILLDECH
ERLSSQFSIDLIGLLYSGNSEEDSEKLQNTQITQPVIFAISYSLAKTLELLGIEAKAMIG
HSIGEYVAATMAGVMTLDEALKLVATRGIIMQECEPGVMLSVAAGRDDLEPFLTDKVALA
TVNSPNSCVIAGSQADIEKVQQRLVDKNFRTRLLKTSHAFHTPMMKPGAEKFKAALAEVN
WQKPTKAYISNVTGQWITPSQANSVDYWVEHLCQAVEFHAGIMTCLEKQGLNVFLEVGPG
RTLSTFVKQIAASDANISTFNVIRHPLEAENDRNYLLKLVGQLWMRGSSINWPLLYQNTH
PKRISLPGYQFVGESMAMGTSVLAARGSEKASETKIQKNQISEWLYTEAWEDISLPDEAT
RSDIRVALCFVPDITWCQPLCNSLKLDEKSIKFVLPADAYTSAENVITLVPGDKRHFGKL
IDELKQDALLPDSVIFAWPLSGQSDLETSWFSVITLIQSWTTSGSMTDFRLLLANTKQPE
HSMLNGLVKVITQEVSKCHPRLVQISPLESIERQCEILTGELLATDERFIVNRTQTGRST
LAYHKLKAGLLKENTLLKNEGVYLITGGLGDLGLLFAEYLIKEYGAKVILSGRRALPGKH
EWKHLVSIDHPEAEILQRLDELSELGKGEVAYYSSNVSDKHEMQVLLDAIEEQYGCLHGI
ICAAGVTRGNSFQGINKLTLEDCTPQIETKVEAYKILAELTENKPLDFCLLCSSIASVLG
GLSFSAYSSVSSFADAFAKQQNSQGKPWISVNWDGWVFERNDAGDPIGSSLDQLLIEPDE
GLKILECALQSPLRGQLIISTGDLDKRFEQWVGGHLKPFKLNESNHSQRAVVSKAQIVGT
IVSVWQDFLKITNISRDDNFFELGANSLDMVQVNKRLTDALDMDFSVVDMFSYPTSELLA
DFIVNQYGITHETGEQAEHSDTLNQHRDPSAQLDQSSTPIDRQIAIVGLAGTFPGAENIH
EFWENLTFGKESVTTFSKEELSEEGIDSGLLENPNYIRAKGVFPNAGEFDAEFFGYTPYE
ARQMDPQVRALHTCCWQALQDARIATKDNRAKIGLYASASGNLQWLAQAMATAEGSAGQY
SAMTVADKDYMSTIVSYKLNLTGPSMVLSTACSSSLVAVNEAVKSLRAGECDIALAGGVS
ITLPIKAGYVFEEGMIHSKDGKCRAFDIQASGTVFGDGIGIVVLKPLKQALADNDNIYAT
IIGTAINNDGGMKVGYTAPSTKGQVEVIQSALRDANVMAESIHFVEAHGTGTTLGDPIEF
NALKQAFSTDKKNYCRIGSVKSNIGHLNSAAGIAGLIKATLAVKNRILPPTLHYARPNKE
IDVTNSPFIVNNQYTELNDTRNPIRAGVSSFGIGGTNVHVVLEEAQVNKDKSFNKKVDNR
LPIVLSAPDDKSLQCYKQQLKTFVENNQQQMSVSDIAYSLMQREPMASQFVASACDYDAL
IKALSSGEKDNVKVKPGTTKRKVVFLFPGQGAQYVTMGHELYHSNGLFKEWCDKGFTLAD
KYCSIDLKSLFHSRDEDRNLYNTEFAQPLLFIIEYALAQVLKSYGVTPDAMIGHSLGEYV
AAALAEVFSFEDAIKMICVRGKLMQSTEDAVMLSVMSSSESVKEILTGSLEIALDNSSDL
CVVAGSDSDISSFESDCEAKSIKTKRLRVNKAFHTRYMEPVLGDYAGIIREIAFNKPQIA
FISNVTGKWAETDKVVEYDYWVNHIRQPVRFKESITEVLKEGNCLFIEVGPGHGLSTLAE
NHSDYHANHICISCFDRKNEEINKHSELVQKLGKMALLKIDVNWHAEMADLQPRLVHLPP
TPLRGTKYPTDIKRLQALFSGNKNLGYQADKPEEPVSQSKAGSNPHPKAKRSVIDELSAI
WKLILGVDTIKEDDDFISIGGSSLSAVQVIAKAKSVNLPVNMSMLLSGQTLVQISASLQS
DDETTHKGWQFNEHFSPEMYPGSASCLYSAVREKLKHEHGLTSDDAIMQVVDGSPLLGIG
VQQFENATKIVSKPVNYGTLSGWPSLQECYSFSYDKQFFEDYEAYRHYCESELALGHLVI
VTGSDYYLPFSPSYGLPESEYIKRPLFENIELGDDDIIPHAFVLVGKTPSGYQIYDGSFQ
YFGEITEQEFEKTVIGFKGLDFMQSHEVYNKSRSFMVITVTCDGKFHKDNDLKEQTLNRL
VTDFQTKQAIESNESHLSYYVGLTALDKLIENPGLIASSSNFDLAEIFSRWYQQMLLLRK
FLKISKPEVSTECDHAFSIISEELDKVVACCKNSSDDKTIIDSLLLVKSNLSDIIKNLS
>A0A2P4UHJ2|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Actinomadura rubteroloni|TrEMBL
MHEPIAIVGISCRLPGGNDPHRFWRLLREGREAVGPAPEGRWSDVAPELRRGGFLDRIDG
IDLRFFGVSPREAAVMDPQQRLVLELGWEALEDARVLPGNLRGSRTGVYVGAIWDDYAAL
LRSHGAATVTQHTLAGTQRGIIANRLSYTLGLHGPSLTVDTGQSSSLVAVQLACESLRRG
TAERAIAGGVNLNVLGAGTLGAEKFGALSPDGRCHTFDERANGYVRGEGGALVVLRPLAD
ALADGDRIYCTILGGAVNNDGATDALTVPGRRGQEEVLRSAYRDAGVSPADVQYVELHGT
GTRVGDPIEAAALGAVLGAGRGDGERLLVGSAKTNVGHLEGAAGVTGLVKAALSLRHGEI
PASLNFVRPNPEIPLDDLRLTVQTGLTPWPEARGAVLAGVSSFGMGGTNCHLVLGGAPAA
ERAAAPRPVPATVPWLISGRSPKAVRAQAAKLLDFLAERPASAADVAASLATTRTAFEHR
AAVVGNDRAELETALRDLAESGTGAVSGRTTDGGLAVLFTGQGAQRIGMGRELAGAFPAF
AAALDAACAELDRHLPRPLREVMWADADSDDAALLDQTRYAQAALFAVEVALYRLAESFG
VRPGHVAGHSIGEFAAAHAAGVLSLADAAALVAARGAFMQDLPAGGAMVSVRASADEVRD
VLTGAVGLAAVNGPRSVVLSGPEDETLAVAAALEAAGRRTRRLKVSHAFHSALMEPMLDR
FRAVAAGVEFRTPRMPVVSMLTGRVADDDLRDPEYWVRQIREAVRFADCVTVLRDAGVRT
FLELGPGKVLTALAEENLDAEDTLFLPSLLDGVEERTFVTALAGLHGQGVAVDWRALLGD
GTADLPTYAFQRRRAWPEPAGAADAASAPAPAAPEPEAEEDEGDDGPFSRRGLAALGAAE
AHRRFVDLVRVGINATLGYGADDTLDLRDTFKELGFDSLSGLELRNRLQAMSGLRLPTTM
IFDWPTPLGLVERLRSDLLEEPGEVPPAPLAPAVTDEPVAIVGIGCRFPGGVRSADDLWR
LVGDGRDAITEFPGNRGWDLRALLDGDPDRPGGSSTRYGGFLHDADTFDAAFFGLSPREA
TAMDPQQRLVLETSWETFEHAGIDPSELARRPVGVFVGATAHGYGPELRESVEGYDGFRL
TGSTVSVASGRVAYSFGFEGPAVTIDTACSSSLVALHLAARSLRSGECEMALAGGVTVMS
SPGMFLEFSRQRGLAPDGRCKPFAASADGTGWGEGVGLVLLERLSDAERNGHTVLAVLRG
SAINQDGASNGLSAPNGPSQERVIHQALANAGLTADEIDAVEAHGTGTTLGDPIEAQALL
NTYGRHHTDDQPLYLGSVKSNIGHTQAAAGVAGVIKMVQAMRHGVLPRTLHLDEPSPHVD
WTTGHLSLLADATPWPETGRPRRAAVSSFGISGTNAHVVLEAPPMAAPDAEPDGPVAPTV
ALPLSAKTPAALRAAAGRLAEHLAAHPGTVPSELAGALAGRAILGRRAVVVAGRDDHAEA
VAALTALAEDRPHPSLVLGPETLPSGGGTVFVFPGQGSQWAGMGVQLIAESPVFAAAIEE
CAQALRPYTGWDLHDVLAAPDVPTAIDVIQPTLFALMVALARLWEHHGVHPGAVIGHSQG
EIAAAHIAGALTLDDAARIVTKRAQALTTLTDSGRMVSVPLSPADAEALITRLGLTGDLH
VAALNAPTRTVVAGTTPAAEALIAHCETESIDARMIPVDYASHTPHMHALRAQLLNDLGA
VAPQQAAIPFYSTLTGGLVEDTTTLDATYWYDNLANPVQFHPTLTELAARHSTFIETSPH
PVLVPAIRETVEPPVSAHPTLRRDDGGHRRFLTSLAAHHTHAAAPVRPAAPARPSTSLPT
YPFEAERYWLAPAPATANAAGLGLGPADHPLLATTTALPDGRWQATGLLAPDAPPWLADH
AVHGTPLLPGTAFLDLALHAGQAVGCPTVDELTLQAPLTEDGVRDLHVAVTAPDEQGLRR
ITVHSRPHDGDEGWTEHAAGVLAPAAAEPVAAVMSWPPQGAAPTDLGGLYPALAERGYDY
GPAFQNLRELRVAGNVLHARVQVGPGTPVAGHGLHPALLDAALHALLQATVLREDGPVSL
PFSWSGVRLHATGADMLHVTLTPLRPGTVSLHAADPAGAPVLTVAELALRPLTADLAARP
TSPAANDLFRTVWRPIETAVTDRPDPVLIGDVPGGYASLAELSAAVASGAAQAPADVVAL
PSVLAAICGRDLDDCDCPDAVAGATADALALLQEWLDAPHLHGGTLTVCTGRAHALPGDD
HPIHLPHSAVWGLVRTAQNEHPGQFHLLDTATEDVTAIAGAVAAAHALGESQLAVREAGT
FRPRLVRAGTDRLLPDAPSGWRLDISGRTGTFDDLMVVPSEARDAALLPHQVRIAVRAAG
VNFRDVFVTLAMREGETGLGLEGAGVVLEVGADVTDFAPGDRVLGLFEHAFASVAVADVR
HLAPLPADWTFEQGASVPIVFLTAYYGLVDLADVRPGETVLVHAAAGGVGTAAVQLARHL
GAEVYGTASAGKRAALHDLGLDDAHIGDSRALTFEAEFLDRTDGRGVDVVVNSLAREFVD
ASLRLLPRGGRFVEIGKTDIRDPATVAADHPGVGYDAFDLLTVPPDRIRGMLDALGGLFA
SGALRPPPVRSWDLLDARSALRHLQEGANVGKVVLLPPRPLDPDGTVLITGGTGTLGGVV
ARHLVTVHGARRLLLTSRRGPGSPGADELAAELEGLGAHVTVAACDASDPDALDALLSAV
PADHPLTAVVHAAGILRDAPVTGLTADRVAEVLRPKVHSAWHLHQQTRDLDLAAFVLFSS
AVGVLGNPGQANYAAANTYLDALAHERRAHGLAAVSVSWGLWERSSGMTGELTAADLARL
RRAGLTPLADERALALLDAALQLGPPHLVATPLPARTAAEHPSPLLRDLTSASLRAAASG
GAASSASWPDLIAALPADERRARVRADVRAQVGVVLGHAAPDALDAGRAFKELGFDSLTA
VELRNRLNTLTGRRLPTTLVFDRPTIDSLTGYLLDELFAGESAEARVVAAPAADASDPVV
VVAMSCRYPGGANTPDALWRLALEEVDAIGAFPADRGWSGDLFDPDPDRPGTSYSRHGGF
LYDAGEFDAEFFGISPREALAMDPQQRVLLETSWEAMESAGLDPASLRGRPVGVFVGAIS
QDYGPRMHQGTRDVGGYLLTGTTTSAISGRVAYSFGFEGPAVTIDTACSSSLVALHLAAR
SLRSGECEMALAGGVTVMSSPGMFLEFSRQRGLAPDGRCKPFAAAADGTSFAEGAGLVIL
ERLSDARRNGHTVLAVLRGSAINQDGASNGLSAPNGPSQERVIHQALANAGLTADQIDAV
EAHGTGTTLGDPIEAQALLNTYGRHHTNDQPLHLGSIKSNIGHSQAAAGIAGVIKMVQAM
RHGTLPKTLHLDEPSPHVDWTTGHLSLLADTTPWPDTDRPRRAAVSSFGISGTNAHVILE
APPEAEPAAEGTGPPVVALPLSARTPEALRAAGARLGAHLAAHPDATPGALAGTLAARTS
FDRRAVVVAERDDREVLSEALAALTVGEEHPALVTGRVRDGGLAYLLSGQGSQMPGMGHG
LYDTSAVFAEAFDTVCAAFDPHLDQPLKDVIFSDSDLINDTAYAQPALFALQVALHQLLR
HHGVTPDVLIGHSLGELTAAHLAGLWTLTDATALVAARARLMGALPAGGGMLTVQAPESA
LPPLPDDVAVAAVNSPTATVLSGDLDALERVAGQLTEQGVTTRRLTVSHAFHSPLMEPIL
AEFGEVAAGLTYHPTTVPIVSNLTGRTATDEELHDPAYWTDHIRNTVRFHDGLTHLHTTH
DPALYLELGPRPTLTTLTHQTLADAADVEPVLDHRLADDVAFLTALAHLHTRGRAVLPPS
GPAPDTPPPTYPFQRRRFWLAASAGAIEDVAELGLGPADHPLLATATPLPDGRWQATARL
SLETQPWLADHAVHGTPLLPGTAFLDLALHAGRVTGCPTVEELTLQTPLFLASGRPRDVH
LTVTPPDEAGRRALTVHGRAGDDATWTEHATGVLAPARVFPAPPATEPPAGAEAVDLVDV
YERLAEHGYDYGPAFQNLRDLRRDGSVLYGTVRLGPDLATSGYGPHPALLDAALHPLAIQ
GLADGETPLPFSWRDVQAVPSDAAELRVRITVTEPGTVAVVAVDSFGEPVVSVRALAMRP
VSADEFRRAFTDRDAPSLFTVRWSPVPPGGAPHAPDRVLEVASDGGPRAVTGRVLDGVRA
WLREDRPADARLLVVTRAAIASETLDLAQAPVWGLVRTAQAEHPDRIVLLDADGDVTADD
AAAALATGLPHLALRDGRLLCPELARHPSEPGRLTGDGTVLVTGGTGTLGALVAEHLATR
HDARHLLLVSRRGPDAPCADDLKARLEELGAQVTIAACDTADPDALADLLAAIPEEHPLR
VVVHAAGVLRDAPLESQTDEHLAAVFPPKVDAAWNLHRQTRDLDAFILFSSAAGVLGNAG
QANYAAANTYLDALAHHRHSQNLPATSIAWGLWEHSSGMTTDLTPADLARLRRSGITPLT
DAQGLALLDAALGSAEPHLVAAPIVPRAPRTAAKPAPRATGLGQRLAGRPEAEQTHVLTD
LVRTHVAAVLGLESGAAPDLDVPFKDLGFDSLAAVELRNLLSKATDLRLTTTLVFDHPTP
GALAAHLRSELTGAGRAAAAVAPARGAAPDEPIAIVGMGCRYPGGVRSPRDLWRLVAGGV
DAVGPFPADRGWDDDLFDPDPDRTGKSYARHGGFLYDAGDFDAGFFGISPREALAMDPQH
RLLLETSWEAMENAGLDPAGLRGRPVGVFTGVMYDDYGSRVARSSGSLEGYLVSGSAGSI
ASGRVAYTFGFEGPAVTIDTACSSSLVAAHLAAQALRSGECEMALAGGVTVMATPSVFLE
FSRQRGLAPDGRCKPFAASADGTGWGEGVGVLLLERLSDAERHGHPVLAVLRGSAVNQDG
ASNGLSAPNGPSQERVIHQALANARLTPDEIDAVEAHGTGTTLGDPIEAQALLNTYGRHH
TAELPVHLGAVKSNIGHTQAAAGVAGVIKMVQAMRHGTLPKTLHLDEPSPHVDWTTGHLS
LLAEAAPWPETGRPRRAAVSSFGISGTNAHVILEQAPDLEPAAPDTPETVIVPLSAKEPA
ALRDAAARLGAHVAEHPDLTPGDLAGSLSARSRLAHRAAVIVGCDDRDVLTGALAALAAD
EPHPALVTGLPERDGGLVYLLSGQGSQTPGMGRGLYDTSPVFAEAFDTVCAAFDPHLDQP
LKDVIFSDSDLINDTAYAQPALFTLQVALHHLLRHHGVTPDHLLGHSLGELTAAHLAGLW
SLTDATALVAARARLMSALPPGGGMLTVHASEADLPPLPDDLAIAAVNGPRSTVLSGPVD
ALDRFTASLDERAVKHRRLTVSHAFHSPLMEPMLAEFRKVAESLTYHPTTVPIVSNVTGE
TATAEQLGDAAYWTDQIRSAVRFHDGLTHLHTAHHPALYLELGPRPTLTALARSLGDAVV
QPTLDPRGPEDVVFLTALAHTAAAPAAPARRIDPPPTYAFQHRRYWLAGESSPETAAGLG
LDGSDHPLLGAAVELPDDAVAFTARLAPGAHPWLLDHAVHGTPLLPAAALLDLALHAGRL
VGSPALDDLTLHAALILAPDDPRDLQLVVGAPDEGGARPVTVRSRPHGPDGEWTLHATGA
LGAGDPGPVAVPPVPADAETVDVTDAYPTLAERGYDYGPAFQNLDELRTAGAALHARVSL
GEDADPAGYGVHPALLDAALHPLALGDAAGEGRLVLPYAWSDVRLHASDATDLRVAIEPA
GDDAFTLTASAPDGTPVLTVGSLTVRALPADALARRRRDPLYALTWSAAPPDAEPLAADP
VVLTAEDLPDTVDAVRPTAERMLAELNERLAADDAPLAVVTTRAVATGPGEAPNLAHAAL
WGLVRTAQSEHAGRITLVDTDGSPASAAALATAVASGHPQLALREGRALVPLLAALPAAA
DAPARTGTTLITGGTGALGALVAEHLATRHEARHLLLVSRRGPDAPGATDLKTRLEALGA
QVTIAACDTADPDALADLLAAIPEEHPLKTVIHAAGALKDAPLISQTPDHLATVFRPKVD
AAWNLHQQTHDLDAFILFSSAAGTLGTPGQANYAAANTYLDALAHLRHSQNLPATSIAWG
LWEHASGMTAGLTAADLNRLRRSGIAPLTDAQGLELFDAALATDHPAPVPIALNAPALRA
AAVEGTVPAVLRDLFPARSARRGAAPAATWPGRLSGRTPEEQAGLLVSLIGGQVAEVLAH
DTAAAIAPDRGLFDMGLDSLTALDLQNRLSRATGLRLPSTLVFDYPTLRELGDFLRERLT
TGTSDGAADHLAALTDLESAFATLPDDELCTAAARRLRDLLDRITAHGKDDGEPFTDADD
DALFAFLDGDAR
>A0A139Y074|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii ARI|TrEMBL
MTSDLTQALLSCLEAVTEPDSEDTPNQRTDAEYRFCAVRQDDITFAEFLNRVSVQFEVPI
GPLAAKDYESFSSFVFHICELKKEKQVNVKTSSHHIIHRTNRYSTENEKASISIVGIACR
LPGNAKNPGDFWTVLVEGIDAIVPIPSKRWNHKEFSEGHSERGTIYVKEGGFIDGIEKFD
NGFFKISSSEARRMDPQQRMLLELSHEAFESAGLQAITDDNHKFGVFVGCSSSECLMLVP
EATVALCAAGMLALDSRCRPFDAAANGYGRGEGAVVFLLERQMYSPESRCKQKSLATIRG
HGTNHNGRSVSVTAPSDVAQKKLLEGVLRTASVEPQQVAYLEAHGTGTKLGDTIEFRAIK
SVFSTSRSVDNPLLIGSGKSNVGHLEGCAGAVGLLKALLVLYFREVPPTLHFKKISPLID
DEGFDYQIPTKRLTLAGDRPILAGVSSFGLGGCNAHVIIESVPKDREMDALSLSRRHIWD
HMEFPVFESADDGNSFGGLAMRHNVDLCNSTCNHLRRRSTSSLIGKCTLTPVSARLRRFT
AFSSGDGTPGLRVQQYGTTEGSSKANEPHAITEKQISRWTRDSRKGLYVEVESMKDELER
SFSLEDDNGSVTGSVQTEQTEPDQMANEVVNTVDEEAVQTLVLQTVRQILKEAVSIHRDV
SLKTLGIDSLAAVEFRDSLQESLGISLPASLIFDFPTIDDVCRFLAQKLQSGDGGERRNT
PTNLAQPRPSTSSETCVAVRGMSCRFPGAEDGTTESFWEMLHSDSDCIQEIPTSRFDAAS
IFDTDYDARDKIYVKAAGILRGADMFDNTFFKISEVEVRHLDPRQRILLEVAYDALVDSQ
VLGDQGLAAIDNEIVGVVIGCSGNDWNTFLQQHALSASSFSGPGTSPALLSNRVSYNLSL
RGPSLTVDTACSSSLVAIDIARQLLNASQCNLALVGGVQLLLTADTFIHYCRARMLSPDC
RCKTFDASANGYVRSEGCGVVLLENTHDRQVSKNTTYAWLLGSANNHVGKSASLTAPNGP
AQQAVILASLRSAHLQLTSQIHLIETHGTGTSLGDPIEIGALQAVYGQGTSADTPLVLGA
LKSRIGHTEGAAGIAGFIKLICSLRQRIAPPNLHLKTFNPHIDISTADSSRPFLFPTKAY
PLDTLMAGEKTEALLGAVSSFGFGGSNAHAIVEV
>A0A139Y069|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Toxoplasma gondii ARI|TrEMBL
MAGAVEPVSRLFERVEFSEPAIPFISTVLGRLAVGSELSDALYWSEQITKPVRFREAIHA
ATSGEFSAMQAYIEVGPSRVLAAMGRDCDSGADGTIHEWLCTVDPRSAANPFEAIATLQE
RFAQRLPMDESVRHTWNHSAFPWTVPRHPLIGKEMPTVSAAGGEQVSRYSSRVRLDVLDA
LRDHVILGMPLMPGAAFIDALLAAGRLEHTRIDRRISSSAVIKLSDVSIFSPLLLPESLG
SGVAPGEQGFHPSSLELSVEMKPDGRDHLAEVRSRRIGTTLAAANEEEYEQSHCRGRLAI
SAGTSQLPASTGGQLTDLQRRFYSEAAVDVSQLYATFAELGWQYGKLFRPIAQLFKTDTE
AFAELRLPRPVLPCEEGFIIHPAILDGLFQVAGSLLLTAEKAPAGSVYVPIGVDELAFIP
STSKRDIVWGRVTFAEADDEAKRRQERVVNCTLYDEGGRVLLYVSGLRSRLLRTEVLLSG
TGAAAESNKLWSVEWRASHQQPVAHHEEPVDHSTNWLIAGVHPAVQSQLEEFFLKTMPGA
KVVFCAPSVVATDVRRLLQQEAWNGIIHIGGVTASISEMECLSDVLVLLQAVIDWQANES
SPRPLPAMFLVTRGACCEATENSGLSHSLAPVHSGMRGLFRTAKAELEALWNRFVPLHYI
NIEPSSDKQTVTPEELRQVFSVIQQQGAKAQFIQDQLTQEPSKPLFYESESLLRDGELLL
PRLVPASLEDCGDGNALAEAMTGTIVITGGLGGIGLVLAKWLTGQEARAVVLVSRTGTPS
AEVQRSEDWHLLQSRRQHQTRIVTASCDIGDREQVKLLFRSLRAGSFVCHSTGQVVELPP
IRGIFHAAGVLRDCPIQKQDAETLASVFRPKSQGAWNIHNALEELNMNEGLKVFLMFSSI
ASLVGNPGQANYAAANSSLDALASYRRCRGLAGHSIQWGPWIEQGMAAELGERLERAGFR
GISNKVGVEVTEAVVSQGTTGDFVVACQEFIWPRFVMRYRGCLPAIFEEQTRSVTVRMRD
ERSSRQAAGPEMHQESAFASMAPDELRALIQATVSGAAKQVLGTAEEPPADAPLQALGID
SLGAVEFRNAVQDAFDIRLSATLLFDYPSVQAVSDHLWSMVRAKTAIDTSSRGDDQLASA
AVLQDAGVSIAVVGMACRLPGSVNDLEAFEEMLLTFQDCIQEIPPSRFSIEEVYDPDPDA
KGKIYVREGGFIDGAELFDNRFFGISDAEAREMDPRQRISLEVSYEALGTNAEPIRALSN
I
>H1KFY5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Methylorubrum extorquens DSM 13060|TrEMBL
MRMHTANSKDAHETKLLLQQWVSSTICDVTGLDGDRVGPNARLEEIGLDSLAIVSFGTRL
EQHIQGLRRSFIFDCRTVGEICDHLLTHHQPELGFLISQAASTPKQLGERPFQKGADPAS
EAEDWPEIALADFGTGRETAQSHEMSPRESIQRDRLHLDNAVAIIGMQGQFPGAASLDAF
WQQIASGADLVGEIPADRWSVEGFYEAGSASRKTGKSYSKWGAFLPGVDEFDAQFFGIPP
RDARLMDPQERLFLECAYHAMEDAALLGARQESLRRDVGLNIGVFVGITTNTYNLQGPSH
WTAGGVEVPTSMPWSSANRVSYFLNLSGPSVAVDTACSSSLVALHLAVESVAAGECAAAI
AGGVNLYLHPAKYVQLCQYQMLSPTGRCHSFGADADGFVPGEGVAAVVLRPLRDALQNGD
RILGVIRGTAVNHSGRTNGYTVPGAASQAALIRKALDRAALTPDSIGYIEAHGTGTKLGD
PIEITGICDALGDSGQPCAIGSLKSNIGHLESAAGIAGIVKVLLQLRHDRIAPSIHSRIP
NPDLKLDGGRYFVPQDLGPWPKAASDGRRRAGISSFGAGGTCAHAIIEEGPEVPVSSAVG
PLVFPLSAQSPEQLRLRAQDLLKWVGMVQPGDERTTLLRLAYTLQCGRATYRYRFAAAAA
SVRDLAAAVGTFLGEVATVAILGSQGVEDSEDARLAARWSTGEEVPWPTLWQGLPCPVGG
LLYPFLRDRHALAPPEIRMDSGRERPGEQVEIVVSHTFTGDESYIRDHVIGNSPILPGTA
YVGLCSVLIGQAGGDGWAFDLQDLAWSSPYRWVPTAAKQLLVRGRRLGPSLSIEIASSSD
ARPLHFTARADLGGRSPTADGEPIPAIRERCTRSADVAGFYALAADFGMVFGESFRCIAR
ASKGRGEALVEAKLPTGSRRGGTTGLPIDPGLLDAVFQSAFFSVEEGFDGPHVPVRAKAV
RIHGDLGSNLVIHVRAVAQASDGFTFDYRLLAPSGAVIGEIEALTFQRIEAVRGRSALAE
RSINIFEPVWLPDAAVGFGGPPTALLALGRQDRNDIRLGLTGGTTQVRLRPGGAFEIDGS
RTVTLDPERKDHLEHLWRTFKADGSLPAAVVADLRHQPAVSPHGLERHLGLGPFIGAMAL
LKSVVEAYAPSKSCRMILICQGPAASAAAAMMRSVHIEAPSLDFTVLETDGAEHPAYLDQ
FVDAEAKRTAGGGVRHVRFIGGTPLVRRYAALDLPSRDADVRSGDVVLITGGLGAVGLHI
AKHLALHRGVRIALLGRSRPAEHSRAAVASLRMAEGDCSYWECDCSSGEDLTQTLADIRS
RMGPLTGILHCAGVLKDAFFTRHTDTERYEVLKSKALSARLLDEMTRQDPLRWFVLSSAL
AAVCGNIGQSVYGLSNGWLDGFAEERNSLTAAGRASGRTVAVAWPLWNTRTGMQASERFL
RRLQDEGLDLLEPDEGARLFAAATWSDRSLIVPIKGDEERSSRILGIKDAGIPAGNTDDA
TLEPQPGTADANGGQEDRVLRYLIGTLSDVTGTAPERIEPDTPLEAFGLDSLLVLEMSDR
LQERFPRIARTALFEARTLRALARLLIDELPLDVAKLVASGVSVEDDEPLEEPTRPAVSA
AVVGGSPEPGSTTGNRPAIAIVGLAGRYPGSADLWDLWDHLCAGSDLVTELPPRLSAGEE
RNGVYAKWGSFIDDVDTFDPLFFGISPRDAERMDPQERIFLQTAWHAVEDAGYTPEGLSG
GSERGTRRRVAVIAGVMYGEYQFFGAAGTSEGGALTNSSYASIANRVSYCLDFDGPSFAV
DSMCSSSLTSMHLACELLQSGGCDIALAGGVNISVHPYKYRMLSELKFAATDGRCRSFGV
GGDGYVPGEGCGVVVLRPLEAALAAGDHIYGVIRGSDIGHGARSSGYTVPNPDAQAEVVR
RAFERSGVDPARLSYIEAHGTGTSLGDPIEIRGLSKALGRQFPEGGTCAIGSIKANIGHL
ESAAGIAGLTKVLLQMKHRRLVPSIHSAELNPFIDFNQTPFRVQREQAEWQAVGGRRLAA
VSSFGAGGANAHLVVESWDHPTMPEVASREPLALLLSSANEGQLREAARVLLKHLEREGE
ISPDAGQYWIGSQHFSLRDVALTLLHGRRHGDHRLAIIAADFDEFRRKLALFIRTDSNVG
AASGDFERLGILIGGLQPTVQGDAIYREARAWVDGGPPPPPEAPWRRVPLPGYVFQRRRF
WLGSLPAENEDPDKAVVDLHRSPPKTKDPDLTPSGIIAKVKAGDMTQETARELLLAMR
>A0A7K0CKT0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces smaragdinus|TrEMBL
MDEIAVVGIDCAFPGATGTEAYWTLLMSGGDVIGPVPGQRWDPADFPGTPDSGGFLADAD
AFDADFFSVVPRDAAAMDPHHRLLLHCAWRALENSGRAPGELAGSDTGVFVGVMGGEWGR
LTVGGHGRMTPQHGAGSSAGMAANRISYHFDFTGPSLAVDTACSSSLVAVHLAAGALRAG
ECDTALAGGVNVQLSPALGEVYAQMGLAARDGRCKPFGASADGIGRGDGVGLVVLRRLGD
AIADGQRIYAVLRGSAVNQDGRSNGITAPNRWSQQRVIDAAYRRAGVAPADVRFLEAHGT
GTALGDAIECAALGTVHGVERAEPCAIGSVKGNLGHTEGAAGIASLIKTALALHHGIVPA
SRYADQENPQLRLAARGLRLLKSPLRLPPGESVAGVSSFGMGGTNAHAVLATAPRTRGPG
RRPARARGERTAGFGVFTLSADTPEALARNLAAQAEAVARRPRGRATGLCWSSNLVKTGL
PYRFAVAARDSAGLTDELRAAAAGEGHEPHRPWRAPVVALLFTGQGAEFPGMTAGLYRDS
HTYRQHLDEADKAIAPHLGLSVRELVLGGDERVLEPRYAHPASFAVGWALAATLGSLGVR
PAGVLGHSAGEYAAAVHAGALELDEAARLVVRRAELMARLPDTGGMLAVGLGAEEIGRRR
DEAGDAWRDVTLAVVNGPHDTVLSGPRDTLRGLAERFAAQGVRTRLLAAARAFHSPDVAP
VAAELRTEPVACNRPVVPYASTRYGRLLGEEPLDAAYWAGQAERPVLFDDALGALVATAA
PTHLIEVGPRPQLLPLAGRTGRVAGLDLLHPAHGPDAAGRELAELVAALYRGGLDPVWEA
LYAPEERVSEPLRPYEFATGHRFWDRQAGPGEPAAAPVTRPDDDPGAAGSEGDEPPDEVL
AAVTAAVAEVGGHAREKVVRGARFYEDLGFDSVMIMQLKDRVEHRLPQAGEVSVQELLPA
LRSVGSLADFLSGLVMANTR
>A0A1N0NW58|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides abscessus subsp. abscessus|TrEMBL
MVGLIKLLLSGQYGHIPPSLFADNPTTKIDWSMTGIRLATKLHPWEPKDGIRYGAVSSFG
AGGANAHAIIAMPAMDTQGEDGDDF
>A0A2X3LLR7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Frankia sp. Ea1.12|TrEMBL
MEVAAVNGPSATVVAGEPAGLDELLSVWEAEGVRVRRLPVDYASHTVQVDRVRDRLIAEL
AGIVPRVGTVEMWSTVTGSPVVSGQLDGEYWFRNLRSTVRLHEVADALVGEGHRVFVEIS
PHPVLTAAIIETAEAAGVPDAVVVGSLRRGDGGLDRLAAGAAQLWVRGVPVDWAPLVAGG
RQVDLPTYPFQNQRYWLLGDGRPAGGAASGGGAAGWTDLDGLRYRVGWHPLGPEPPRAAP
AAATGRWLVVTPYPAADGVPPLAADAVRALAEDGAEIVSVPVGPAELTREGLSGRLRAVT
GAGESDPRGVLSLLALTGTAHPDGPPRADGADGADGADGADGAVGTVGATATLLLVQALG
DAGIGAPLWCLTRGAVSVGGGDPVTDPAQAQTWGLGRVAALEHPSRWGGLVDLPDTLDGS
ARRRLAAVLRGATDEDQVAIRAGTAFARRLLRAPLGGVEPARRWRPRGTVLVTSTGPLGP
HLAGWLAERGAGHVVLAGSHRADDPDIAALRHGAFTGDVRLTVATCDLADREALAAVVRG
QATDGEGIRAVVHTAALLGLRPLADTSVTDLAGAIAAKATAADWLDELFPTDDLDAFVLF
SSVVGVWGGADHAAYAAANAHLDALAVRRRARGLPATSIAWGLWRPLAESGSAGAAAAED
PGVRRQRARGLGYLEPDRALEALRQVLDHDETHTVVAEIDWTRFIPVFTSAGRRPLFDTL
AEDAEAAGEARPSGVADGDASPAASGTGSPLARRLAALPPAERDRALVETVRTRAAAVLG
HSDATAVEAHRAFRDLGFDSLTSVDLRNGLGAALGLRLPSTLVFDYPTPLALAEFLRVEI
TGGDADDAPAAGVPGAVASRDRSGHGGEHDLLDAEPVAIVAMACRLPGGVDSPEDLWRLL
AEGRDAIGGFPADRGWDLDALHDPDPERSGTSYVRHGGFLAGVADFDAEFFGINPREALA
MDPQQRLLLELSWEAVERAGIDPSTLRGTPGGVFVGTNVQDYGPRALAAGAETEGYIGIG
NAASVMSGRISYTLGLQGPAVTVDTACSSSLVALHHAVQALRRGECSLALAGGAVVMSSP
LMYVEFSRQRALSPDGRCRAFGAGGDGTGLSEGVGLLVLERLSDARRAGRPVLAVVEGTA
VNSDGASNGLSAPNGPAQQRVIRQALAVAGLSPSEVDAVEAHGTGTKLGDPIEAQALIAA
YGRDRPAGRPLWLGSLKSNIGHTQAAAGVAGVIKMVLAMRHGVLPRTLHADEPTPQVDWD
GSGVRLLTEEVAWPARPLPDGAPAGRERAGESGPRRAAVSAFGISGTNAHVILREAPATE
EPRVGPASSPASSPRPVPLLVSARTTEGLRAQARRLAAHLDDRPGPAAADVALATAATRA
AFDHRAVVVGADRDELRAGLVELAGDQDPADGTAPAAGTAPVDGMAPAGVGRPGGLVVRG
VAVPDPRVVFVFPGQGSQWSGMGRELLESCPPFRERMTECAAAFEPYLDWSLLDVIRGAG
DAPPLEAIEVIQPALMSMMVSLAAAWRAHGVTPAAVVGTSQGEVAAAHVAGALSLADAAR
IIALRSRLLATRLLGRGALASVGLPPADVAARLDRFGGRLAVGGINGPRQVTVAGETGAL
DDLVAELTAEGVRARLVAASVATHCAQVDGIRPELMEILRPLAPAPARIPVYSTVTGGPL
DAVALDAEYWYSNTREPVLLDGAARALLAAGFDTFVEVSPHPVVGFGLAETAHDAGRDAV
VVSTLQRGRGGADRLLAALAEVHVHGVGVDWREAFAGTGAHPADLPTYAFQRRRFWPRPA
PARPADAVAAPGRDGPAHPLVTAAVPMADGGLLLTARISPAAQPWLAGRTVAGVPVVPDG
VLLELAIQAGDEVGCPEVTDLALTGPLVLPESGALRLQLHAGAPDGTGNRALTVHARPDG
APADAPWTAHATATLAGTADPAASVPDPRAWPPPGAVPVDVDRLYGELLAAGHGHGPDGP
RLTRAWQAGTELFAEAVLDGEHEVAGFGLHPVLLEAAGHLALWGRLPAAGAEPPAEPPAV
SEPVVAVDGGYRGVRLYATGARAVRVRVGPAGAGAVSVELADHTGAAVAAYGSTGLRPLA
AARLRALRASAADAMFALDWVPVAPARASGAGAPGWAVLGPDPLGLRTALALAGVHAPAC
PDLAAAAALPAIPEVVLVTSDSAAAGPDLAAAARTALRSVLALAQEWLRDDRFAAARLVV
VTRGAVAVGAHDDVTGLADAAVWGLLGSAAAENPDRFLLVDVDGTPASERALPAAVACGE
PRVALREGAVLGQRLVRAPVAGAGVDAGRARWRPDGTVLITGGTGTLGGLVARHLVTGYG
IRNLLLVSRGGAGSPGVAELTDDLTALGARVTVAACDVADRAALTGVLAAIPAAHPLTAV
VHAAGTLDDGVFSAMTPERLDTVLRPKMDAALHLHELTRGDDLAAFVLFSSSAAAFGSAG
QANYAAANTFLDALAHHRRAAGLPALALGWGYWAPRSALAGHLDAAALDQRMAANGLRPI
SAAAGMALFDAALTADRPVLLPMRLDPRAPRAGAVPPLLRGLVRHPARRSVDGAADDPVE
TLARRLAGASGPERDRALLDVVCATAAAALGHMSAAEVAPDRPFRELGFDSLASVQFRNR
LTAATGLRLRPMLVFDFPTPEAIAGHLRDQLFPEVAPAAAGPPAAAPAPAPASASAPAGP
PDPEPPAAPGGGEPASAFDEMDAETLVRLALGEGT
>A0A3N6IYR9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI98-10|TrEMBL
MTLLDVLLDAVREAPAQVVVHVRGDGSELSVTLRELRDDSLRVAGGLREAGVAPGTCVPL
LADRSEDFQPMFWGAVAAGLVPVPLAPDARRVLPVWEHLGRPPVVVDASTASLTGELPDG
VRALTLDALREGPVLRDPVVAAGHDDVAFVQFSSGSTGAPKGVEVTHGAVLANLEQIRAA
SALGADDVVVSWMPYFHDMGLIGTHLAPLAARARQVKIGPLTFAKRPRVWFEVAARHRAT
VLSAANFALALAVRRVPDEVLARLDLSAVRLLLVGAEPIAPAVWRAFALRTRAAGLDPAA
AQPVYGLAEATLAVTFPPPGEVAVPLVLDRASLSGGVAVDAGPGEGAVELMDVGRPVTGC
AVRIVDDAGTVLGDRRVGHIMVSGPQLARGYHRLPGVSAEVFAEGWLRTGDLGFLRDGRL
CVTGRHKDVLFLNGRTFHATDVEAVAAATPGLPPGAPAVVGSTDPVSGAERVVVFVPWAR
PPRDAAEVLERVAARVREALFHDDVRVLALPPGAFPRTTSGKLQRRRLRERFETGEFAAG
WRRAGDGDGLPTEAPGRAEAPRSSAEPRAAAPRARAETVAEAPRTWAETVEAVREVWARV
LDRPAASIGAHESFGGLGGTSLKAMEVLVALEDAFGVTLPPAVIRDHGTVTALAGHLLTV
APGTDPAATSTPACPEATTSTAVIGMACRFPGADTPEAFWDLLVDGHDAVTPVPHGRWGD
GHDRPGAGPTAPRKRWAALLEDPAAFDAGYFGIGEDEARALDPQARLFLELAHEALERAG
YAGPRRRGRRIGVFAAAGDSGYREVLERASSDGSPPPSTALTGNLPALIAARVSQSLDLD
GPALAVDTACSSGLVALHLARRSLLDGECDLAVVGGVNLHLTSAPHRLLEEAGALSPTGR
SRAFSADADGFVPGEGGAAIVLTRLDAARLADDPVLAVVRGTAVNNDGRSMSLMAPNPLR
QREAITRAYEAAGVDPASVTYVESHGTGTAVGDPIELRSLAHAFPVRPDGEPRLLGSVKT
NIGHLLNAAALPALVKVVLALGHRRLPPSLHHAPASRGLAPAGFSVVTEARDWTSAGPLV
AGINAFGFGGTNAHAVLEQAPLPQPSPLPAVPASLSPDAAGEAAVEAPHLLTLSARSAGG
LRDAVAQLTAHLESRPHLREGDVCRTASTSRDEGPHRLAVIADGDLRERLAAIAAGSGEA
GGHVGSVVRSRQRVVFLFPGQGSQLPGQDLALYRTASVFRDTFDEASAVLGPVCGRTLLD
WGLDPEVDAAAQAVTEVAQPLLVASGVALARQLRTWGVEPDAVAGHSVGEITAACVSGVL
SLPEAVRFAAERGRLMGTFTEPGAMIAVRGGEDAVAAAVAASDGALAVAAYNGPGLQVLS
GTVSAVERAALGLDAQGVPTRRLRVSRAFHSPLMRPVGNLLADAARALAPRAPSVPLMST
VTAEWQPVLGPEYLREHAERPVVFGAAVERLAREGYGTFVEIGHGATLSGAVRGATGGHL
AGTPVAHVGGASASPSASGPSTPSDTPEDSGASSASSGRTTVMCALPGRPGDRADTERPP
GDGHGGRTALLETVGRLWSLGVPLDRTALDAGHRRIPLPTYPFQRSRYWPGPPPSSPLLH
RVLWEDAPLPANAAGAVRSVLLTGPDSAFVDRLASQLAAEGIRRYEPGDGPPDAVVLVAG
PAPGQDTGDALGRAQDAALAAFDEALARLDETRADRLLVVTEDVQVTRAVRERARPAHAV
LGGLLLALPQETPGASAVAVDLCSLDTPSQRLAAVLAELASGGTPGRAATVAWRAGRRLT
RRFVPLTNGGDPAPTGATRSVLPPDGTFLITGGGGGIGAALARDLAGRGRPTLVLAGRSP
HPPEGLAEELRSLGATVHYRVADVSVEREVDALLAGLPRLDALFHAAGVVRPGTLRNRCA
EETADVLAAKTRGTLLLSLALRRHGLDPAVRIAFSSVSAVLPGLAGALGDYAGANAFLDA
FAASERHAGRPWQSVNLAAFAGTGMAAAIGTGADEGSTAVRSAGGRPVAPAAALAALRTA
CGVDTAQLLLADLTPSPRPAVLTPSPATAAATGTDPATPRRAPSPSPATATSVSRSTRPG
ARPRTGTEALLRRLLAAALRLPPAGIPDDEPFLTLGLDSLAAVDLVKQLERELDRPLPAT
LFFEYRTVAELAAHLDTTPSPAPVPTPGPAAVPAVHAPVPQGVPFPLTPVQRALYTSSRL
HPEVPAHGYVRQTVQGPLDTRLLGRALAALADRHTMLRIRVESIGSTPDGIGSATPRQYV
APPAALSTWYEVQELSGRIEELETALCNRPFDLATEPPVRAVLARESPELSHLVLVIHHA
AGDGYSLNVLTGELWSLYTALAHGPEYGHAPTLPPLGTDFARYATAAADERSSTDGARAL
ADDRRYWSERLASRREPLHLPYDGDPAALPTAPLATRQSALDAVLTAALEKRAAAHGVSL
FHLLLAVHVRCLARWSGQREIAVNVARARREGRMPGLDRLVGPLADTLPLLCGTDPDEPV
GALAERLAGIWLEGEKHASPTGLDLARLLPAGPSGAGPRTVSPAGFSFSRFPAALDEHCP
VKVRPTAAGTATAATRLSLLCWQDETVLRFSWNFPVRLFAPATVARLDRDFHDELAALVG
PRPDVPDLPPVRSLSGAGAVRSEPASAAPAVTEAPEDPPHRDTRSATLVRRLVGRFRATP
DAVAVDTGDATLTYAELDRASHALAASLLARGVTPGSLVGLLTEPGADTVVSVVAALRAG
AGWVPLDAGHPTARLVDQLTRSGARTVLCHAATRAVGDTLGDVTLVSVDASPPLPSDARQ
GCAAGAGRAAGWVLAPDGGPAPDGPVDAGETAYVIFTSGSTGRPKAVPITHRSMENYLNW
AIGTFGYDEHDRLAQTASPCFDASVRQLLAPLLVGATVVTVAWDLLRDPDRLLTYVEHSR
ITVWSSVPTLWEQLLSASEERVRHGAPRPDLAALRWIHVGGEALSPAHVRRWFDLFGTGQ
HIANLYGPTEATINTSCHIIRARPGDQVRRLPIGRPVSGTEVEVVGPGGECLRPGEAGEL
LISGIGLTPGYLGEPALTEAAFTVRRGRRWYRSGDRVRCSEDGTLEFLGRLDDQVKIRGN
RVEPGEIEAVLETHPDITRAVVLAQDGRLTAFVTPGPGPSGADAVALRLHLAKSLPGYML
PSRITRVGRMPLTSTGKIDRRALSQQTLQPFQEAAVPPGADTDTGLGARAGDVRTPPRTA
TEVRLAAIWSALLRTEDVCREDDFFALGGDSLLVLEVFAQLEKQSGPLPRPTVIYRHRTL
AALAGAVDAGVDAAANAPARERDGTAARLRSLDPAGSPAPFPLTPTQRGFLLAEAMAPGA
TSSGLTRLRLHGRLDPARFQSAVDTLVGRHPMLRTVFPAGARPAVQQELPPSLRLPIDFE
TLTDPEQVEERVTAERARRFEPWAWPLLRLRVLTVAPDEHVLVAHAHHIIGDGYSAALLV
RELTAVYDSLSRGEELATAPLRSTFRDHAVQLAERNDAATTAGPGAGSVRPPGGDRWARL
SAPYRPPVLSAGTSTVTPSGTSESPLFHTHGFTVGPGQVEALRRLAARTGSTLYAPVLTA
YYRALVAATGRADLVLGLAVSGRDDALPDAHRVFGPFARAVPLRPAGPVTGGGRGGPGRP
DDAGFEDDVRRVAAEVAAARAYEGVVPLLPGGLPLASQFFFTYLDFSALGPESGGALTVT
REDGDSAYTPPPAGTDVFLAARPDDGRLRITVRAAARAFTPEELAAFADSIRDGLVRAAA
SAVPGPGRPDRRGGPGRGRWMDAALVGYLPSPADLARLAGLPGTALPREELRTLLFPDGR
PRLLETLRTPLGRSGFVCVPLFADELAPGDDLLGHTTRGVELASSLGARAVSLAGMIPAL
TGYGFDVLRAVGMTGTVPGVPADPALPGVPAASAALAVPAAPAVTTGHAATVVSVVRTVH
SALDATGQELGSLTVAFVGLGSIGCSSLELLLTRAQRPPARLLLCDVPGSGPRLRELAES
LRERGLAGVVEAVESDQGLPDAVYGARLIVAAVSGGGTLLDVGRLAPGTTVVDDSFPHCF
DTSRAIGRMERAKDVLVVGGGLLSAGPSERQVAEGLPAAAVAGYLAQPMVPDTIASCRLE
SLLHASGADVPLVHGPVDAATGLAYWEAAEAAGVRPAPLHLLTRTIDPHMLRRHPWGP
>B2J017|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Nostoc punctiforme (strain ATCC 29133 / PCC 73102)|TrEMBL
MSSEQANSLSPIKRALMALEKMQAQLDAVEYAKKEPIAIVGMGCRFPGGADNPEAFWQLL
RDGVDAIIDIPGDRWDTAAYYDPNPDTPGKIYTRKGGCLSDRLDSFEPQFFGISATEAKS
LDPQQRLLLEVAWEALENANQSPEKLFNSLTGVFLGICSNDYNNMIWQTGGATQVDAFCA
TGNALSVAAGRLSYFLGLKGPSLAVDTACSSSLVALHLACQHLRNQECHLALVGGVHLLL
SPETSVAFARTKMLDADGYCKTFDADANGYVRGEGCGVIVLKRLSDAVAHKDKILAVIRG
SAVNHNGRSSSLIAPNGPSQQALIRQALENASVEPAAVSYIEVQGTSTSLGQPIEVEALA
AVYGKNRPLDNPLLIGSVKTNIGHLEAASGIASLMKIVLAMQHGQIPPHLHLHQPNPYID
WEKLPVKVPTQNIPWDKGDRQRLAGISAFSFSGTNAHIVLEEYTNAENPQGLSRSLHILA
LSAKTQESLVQLTAAYEKYLVGNPELNLADICFTANTKRSHFPYRLAVTAASTLELAGKL
GAFRDGKAVEGLSQGKATTNFPEELQIPDLNSKSINWQSILENVTQSYIKGVTIDWAALY
PDDLCARLQLPNYPWQRQRYWIESGTQINADLSIIDSIKQGNVHQLTQQLSAAENLSADE
WELLSQLLTKLTDPSPSIQQLQRQSLTLTDIQNWLVSQIAKEMGVKPDDIEVQAPFDSYG
LDSMLAISIANAGQKYLGIQVSPLMLVHYPTIAVLSQHLATELAASETEAFEI
>A0A3N6FAR9|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-17|TrEMBL
MLVPVRLDLAALRRQSAGMPLPVMFRSLVRRAAPRAADGRSASSDGGGSFADRLRPLPDA
ERERLALQLVCDRVAEVLGHARGEDVKPHDAFTEMGFDSLTAVELRNRLNAETGLRLPAT
LVFDYPTPMVLAEYILGEAAPAKAAARSVLSELDQLEAVFAALDTADEEPVAEVTARLNA
LVAKWNEARGQAAVTTDDVGNTLDTASDDELFDFIDNRFGR
>A0A3N6F1L5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces sp. ADI95-17|TrEMBL
MVMATPAGFAGLSGQGGFASDGRCRAFAESADGTGWSEGVGVLLVERLSDARANGHPVLA
VLRGSAINQDGASNGLTAPNGPSQQRVIRQALANAGLGTADVDVVEAHGTGTKLGDPIEA
QAVLATYGQDRPADRPLLLGSIKSNIGHAQAAAGVTGIIKMVMAMRHGTAPRSLHLDEPT
SHVDWTAGAVSLLQEAVPWPATGRPRRAAVSSFGISGTNAHVVLEQGDDEGTEPAAGPAA
DAPAAAADEPLIGTPALPFVLSGGSADALREQAARLRSHLLAHEDAALADIGWSLATGRA
RLAHRAALVAGDRDELLHGLAALADGTGAPGLVQGSAPAEPPKVVFAFPGQGAQWAGMGL
ELLDSSPVFAERLRECATALSAYTDWSLLDVLRGEPGAPGFDRVDVVQPALWAVMVSLAE
LWRAGGVEPAAVVGHSQGEIAAACVAGALSLDDAARVVALRSKAILELSGLGGMASVPEP
VDRVRERIARWDGRLSVAAVNGPSSVVVSGDTDALDELLATCTAEGVRAKRIDVDYASHS
AHVERIHERLGEVLSGITPRASDVPLHSTVTGELLDTTVMDAEYWYRNLRRTVRLEEATR
GLLRTGHSVFVEISPHPVLAVGLQETLDDAQANGAVLGSLRREEGGPARFLTSLTTAYVH
GAGLDWTALFAGRDARRADLPTYAFQNRRYWLPIRTGGPGDAASIGLGATDHPMLAAAVT
LADTDSHLFTGQLSAQTQRWTADHVVMETILLPGTGFVEMALRAAEQVGCDLVEELTLEA
PLVLPERGAIQVQLVVGAPDGTGHRPLTVHSRPAEFAAEGPGERPWLRHATGVLAVRDGA
PAPGFDFAAWPPPAATALELEGVYEQAALLGFGYGPMFQGLRSAWQSGEDIYAEVALPED
GRAEAADFGLHPALFDAALQAMGLGTFGPGQGRGEDAGKPRLPFAWRGVRVYATGASVLR
VRLSPSGANGIAFQVADGTGAPVATVDSLDMRPVDPRQLKTAGHGDHDSLFQLEWAEAPA
AAVPTGLHWAVLGADPAPLTAAGVRTDTHPGLPALLTEVEKGAPLPDTVVVTVGALTTGD
AATDATGAGTGDATGDMAQDAHTVARATLALLQHWLADERLTAARLVIRTSGAVATVAGE
TVDGLTAAPAWGLVRSAQAEHPDQFVLVDADDSEASWQALPAALTLPEPQFALREGTVLV
PRLVRTGPAADPAPDTAFDDRGTVLITGGTGTLGSSLARHLVDRHGVRHLLLLSRQGATA
DGAAELLAELRDAGAHAHAVACDTADRDQLACVLDDIDDAHPLTAVVHAAGVLDDGVITS
LTDERLDAVLRPKVDAAVHLHELTRDSALKAFVMFSSAAGTLGSSGQGNYAAANAFQDAL
AHHRRAAGLPATTLAWGFWAQASGMTGHLSDTEVLRMSGGGVTGLSTEAGLTLFDLGTAA
GEPLLLPVRLDLTALRAQATAGTLPPLMRKLVRAAAPRAAAGDDATGTGGVGLAQRLAGL
SEDDRDRVVLDLVRTHAAAVLGHASASAVEPDMAFKKLGFDSLIAVDMRNRLNAASGLRL
PATLVFDYPTPVELAAYLRSEVVPDAAGASDAPVLAGIDRLENLLAAVGSDDEQRTRITL
RLNDMLAKWGDVRVAAEPAAAPKDLDTVSDEEIFDFLGKEFGIS
>F1TC79|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Ruminiclostridium papyrosolvens DSM 2782|TrEMBL
MEKLIDITELGKGDKYSGSTSQIKNLSGKDIAVIGASGRFGCAENLGEFWDGLKEGRDFI
RSLPENRKADSEVYYRLSKADEEEHRYREAAYMDRIDAFDSSIFRIPPREADLMDPNQRQ
MLEVIWESIEDAGYGGDKIRGSRTGVFVGYSSDFSEEYKNYIRTVTNNQEEVSITGNLKS
IIAARIAYILDLKGPAMMIDTACSSSLVAVHLACRALRNGECSMAVAGGVKLLITAPAET
GEQGDTGILSPTGRARTFDESSDGTGLGEGAGAVLLKPLSKAVEDGDPIYAIIKGSAVNQ
DGNSIGITAPNMSAQEDVILRAWKDANIEPETVTYIETHGTATKLGDPIEVTAIKKAFEN
FTNKKQFCAVASVKSNIGHLDHTAGIAAILKAVMAIKHGELPPSLHFKKPNGKIPFEGSP
VYVNDKLTKWESQGPRRCGISSFGLSGTNCHLIMEEYTGHKRQEADKTAANIFLLSAASR
EAFMSLLKSYDAFLSNCSEGEFADICYTANTGREHFNIRLAIVADSLEDLRSKIKFLIQE
GIENTVETDMFHGEHKIVAASKLSRLTGEITEDEKKQLTNQVIAEMDILCGKAGAVEDLD
ELRKLGKLYVQGADVEWKGLYSSGKYNRLNLPVYPFLKERHWISTQVKNAVPVQYDNGSR
GKPLIDECTAESMDIRIYSTRFSAEKHWVLGEHKVAGDYVIPGTTYIEMVCELVAQKDYT
GVIEFRDVLFLTPVAVKGGSEVEVQTILRKDGTYSEFAFDTRPGGESFVRHVEGKFEIRE
AATPLFYDINECKGRLQMLEHFQYGEDADYAVEIGPRFKNLTDIYMGSGEVLAYLSLPQE
YSGDLLDFKMHPALMDTAVNMANSAIGEGFYLPLSYKSLKVYGKMPGKFYCHLVRKNKDA
ASSETGVFDILLIEESGKIFAAIEGYTVKKVHTQKTGTFIPVNKDLDFYETRWLESTALK
ATDGLNTGTVLVFKDKSDVSSALISRLKEIGCELYEIEMGSSFEMQDDHKFIISGVEEDY
HKVLSKVSSKISRIIHLMSIGGGREINTIENLDESYRTGVYSLFYLAKAIMKYKINPLEL
ILVSDNTAVVSGKEHDINSQGAAMFALGRVMENEYSGLRCKCIDMGDGTSASEIIKEMAA
SDTGSYAAYRNGKRYVEEFGKALLTGGKEDEIDIKSEGVYIITGGAGGIGLEIAKYLASR
NKVRLCLINRTALPDRDEWDGIQKRKDDTKLCKKITAIMEIEESGSSVLCYTADVSDFQS
MGIIINELVEKYGGINGVIHGAGVAGDGYLIRKPEEVFRQVVLPKINGTWVLDKLTENLK
LDFFILFSSISGYTFTPGQGDYTAANAYLDAFAQYRDKKGKRTLSINWPAWKETGMAVDH
NALNNESFFKPISTADACKAFEILLDKHIVRVLPSVLNYKIFERGNIKIPFALSEEIRVD
NPIRQKITEPKEAKVILKGKLGNGYSDTEQSLGRLWSLVLGVTEVDIYDNFESLGGDSLL
ATSLLKEMQKTYGNLVDISDIFTYSSIFDMAEYIESKTNKKKEFEKINEEEDTEEARLND
ILDELASGKLSLEEAGGMIDLGVVE
>A0A0F4Z1N5|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Rasamsonia emersonii CBS 393.64|TrEMBL
MAASLSVYLFGDQTADFQDDLRALLLVKSNALLATLIDQATVSLQREIQSLPWSQREQLP
SFGNLLDLLSIGASKPLHPALHLALSCLHHFGLYVCQRDSHGDDVGYTVGFGTGRLAATV
VSCCPAPEKLLPAALETVLIGFRVGLLAANAGDQINVNRKGLASWIVQIETDESDDVLEQ
LKEFSIQKRLPTCSKPYLCAVFQGSLLIGGSPALLRELVDTHHLKASYLPVHAPFYGSAI
FSDRDVDRLVRSFPPTLSDASPKFTLLSGLNGKTVPSQTLHSLLAMAVKAILQEQLATDE
VLSSIKDTVLPDTAKPCTIISIGTNMGSKLVAMIQESGVAEVTYLENKAILNQTAGSQPA
RQQKLAITGFSGRFPGAENVHEFWDLLHRGVDTCSETPPSRWDVKTHVDPTLKGKNTSAT
PWGCWLNNPGLFDRSFFSISPREAPQMDPAQRLALMCAYEAVEMAGLVPDATPSTMRSRV
GVFIGVTSNDWCETNSAQDVDFYFIPGGNRAFIPGRLNYYFKFSGPSFSIDTACSSSLAA
IHLACNALWRKEIDTAIVGGTNVLTNPDVTAGLDRGHFLSRTGNCKSFDDGADGYCRGEG
VGIVILKRLEDAQADNDPIYGCILAAATNHSAEAESITRPHVGAQQALFSKILADAGVHP
NEVSYVEMHGTGTQAGDSREMASVSQTFAPWPQGAPRSRDNDLYVGSVKANVGHGESVSG
VTSLIKVLLMMQKNEIPPHCGIKTRINQAFPPDLHERRVRIAMQPTPWHRNRKPRRALIN
NFSAAGGNSCLLIEDAPEQPARKDRLDTRPAHVITLSAKTQTALDANIRSMADFLQNSDS
VSLPDLAYTSTARRMHYNFRSSYAVRSIEELCQSLERDVANPPKQVRGPPTMIFAFSGQG
SNHAGMGKQLYETNSTFRSDLDRFDAIVQNLGFGSILPYLRGLDEAANEASFSTVQLAQV
SLQMALARLWRSWGITPKAVVGHSLGEYAALNCAGLLSDFDALWICGQRAQLLEDYCHAG
THAMLAVRSQQDEVIASLKGIPVEIACINGPRETVVSGANEDIDESAQILEAKGIKCNRI
KVPYAFHSSQLEPILDHFSRVLDGSAFGVPTIPILSPLLSAVIQAGDEISKDYLVQQCRE
PVNFIGAVQAGEAAGILSDRSHILEIGPGMVLARLIQRTIERPTTIIPSLDPNQDSWLVL
SRSVATAYRVGCNIDWAQYYRDYEYSVLQLPSYAWDLKNYWIQYVHDWSLRKGDPLPAIT
ASAAASKLEIATTCCQKTVHAEFKGDTVHAVWDSDLQSESLKQVVAGHRVNGVAVCIGSV
YADMAITSAKAILQSFQDDTTDTAMILKDMDMQDALIVNDSAEPQIVRIEANCSWQEKKV
EVQISSVDNNGKISKTHAKATIAFTSREQERETLRREMAETGFQIETLKNSVESGLVERF
TTSMAYRMVASLAHYNPSHRGVKAVYMNSTTLEASALVQSAVDDRLPGVFTIHPCVFDSV
LQLATFVLNSNENSKFDEEVYVVRGWDSVFLDDLLTPEERYETYVKMTARDKDVSVGDIA
IMKGKEVIGCIKGVRAQRVPRRLMDVMFRRKTDAAASTLSNDTPATVVEVQEHILREDGR
DSSKLDKALSIVAEESGIALGELKDEDFLSDIGIDSLLILVIASRFREELELDLSANFFM
EVNSIGAIKAFFNGQEDSTSHSGTATPTSSSAASTRATSVSAETSLGEGKHESTSPKKAP
VSTSILLQGTLKPHTKTMFLFPDGSGSATSYMHLPRVHEDVAVIALNCPYMTNPKDWEGN
FEDIANILLAEVRRRQPKGPYYLGGWSAGGAFAHYATRVLLEAGEEVRSLLLIDAPCPIG
LGKLPQAFFDYWRTIHEPGGIVEDRPLPPWLMDHFQAVNENLRGYVASPLPAGKSPKTYL
VWAAKGTDNLAGFTGRHLLTPEEDADLGFLMDDKTDFGTRGWERLIEGEITIERAMTSNH
FTIVRGEGAALLSSQIKRACLAQD
>A0A0F4YMZ6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Rasamsonia emersonii CBS 393.64|TrEMBL
MGSTSHVYLFGDQTGEFDTGLRRLIQAKNNSLLTSFFERCFHALRHEIAQLPPSDRQFFP
RFTSIVDLLARYRESGPNPALESALTCIYQLASFINYYGDEGQVYPLGSDSHVIGLCTGL
LAAAAVSSSRTVGELIPVAIEVVVTALRLGLCALKVRDLVGQYEAQSQSWSAVISGLHED
QALVAIREFSKRKALSPSSQPYISAVSSHSLTISAPPLILEEFIESQLPRDVKPFRVPVH
APYHAPHLYGKVDVDWIFKSRSNGTFANYEPRIPLLSSTTGKVMVAKSFEDLLETALEEI
LLHQLCWDKVLDGCSSVLMSAQTSSCTIFPVATAASQGLMSTLKRVGIPNVVLENSTMET
LKDNDRVNLTGRSEKSKIAIIGLSGRFPDAPSPEHFWEVLYKGLDVHREVPPDRWNVKTH
FDPTGKRRNTSQVPYGCWIEEPGLFDPRFFNMSPREALQADPAQRLALVTAYEALEMAGF
VPDSTPSTQKDRVGIFYGMTSDDYREVNSGQDIDTYFIPGGNRAFTPGRINYYFKFSGPS
VSVDTACSSSLAAIHMACNSLWRNDCDTAIAGGTNILTNPDNFAGLDRGHFLSRKGNCNT
FDDGADGYCRADSVGTVVLKRLEDAQADNDPILGVIVGAYTNHSAEAVSMTRPHVGAQAF
IFDKLLNEAGVHPHEISYIEMHGTGTQAGDAVEMKSVLDIFAPDHRRKPEQSLHLGSAKA
NIGHAESASGVASLIKVLLMMRENTIPPHCGIKTKINHNFPTDLKERNVHIAFKPTPWTR
PDAGKRKVFINNFSAAGGNTALLMEDGPLPCAEHAVQDPRSTHVVAVSARCEISLRNNIK
SLVDYINKNIGNCADKEFLAKLSYTTTARRIHHPFRVMVSGSSLVEVRDALEASVRKESI
SPVPASTPNVGFIFTGQGAQYAAMGKQLYEHFPQFRANIQRFDGIGQSLGFPSFLPLIDG
SVPIEDLSPLVTQLGTTCLQMALARLWMSWGARPTFVLGHSLGEYAALNISGALTAFDTI
YLCGRRAQLLEEHCKVGTHAMLALKASLGQVTPFLNGKVHEIACINAPGETVISGTCDNI
DLLSEKLAAEGIKATKLRVPFAFHSAQVEPILEQLLECAKGVKFHKPSIPFVSALLGEVI
TEANYDVLSPSYLSRHCRETVNFLGALEATRHAKLMGERTVWIEIGSHTVCSGMIKATIG
PQANTIASLRRNEDSWKVLSQSLASVYLAGIEVQWREYHQDFKSCHQVLHLPAYSWDNKN
YWIPYKNDFCLTKGEGPIPQAESQPAHQFLTTSVQKIVEVHNEGGKATVVMESDISDPLL
NPVIQGHKVNGAALCPSSLYADIAQTLGDYLIENFKPELRGSGLEVCNMTVPKPLIAKND
GPQMFRATATADWNEKCASVQIYSVNSDGKKMVDHGSCLVKFSDCNVWKEEWRRHAYLIR
RSIDRLFQRAADGESHKLGRGMVYKLFSALVEYDSNYKSMEEVILDSEQYEATARVKFQA
KPGNFHRNPFWIDSLGHLSGFVMNANDATDSKTLVFVNHGWDSMRCLKKFSADTTYRTYV
KMQPWQNNIYAGDVYVFEGDDIIAVYGGVKFQGVPRQVLNTVLPPAGGFKGLSPATKAVP
PRPVEPIAKVSNAKPAVKSATPSVLVQALKILASEIGVPESELSDDLQFADYGVDSLLSL
TISSKFREELNIDVDSSVFMDHPSVKDLKQFLLQASPSDSSESSEESAFFEDSSSSTDSS
TPGTPGDFCTPGPKFMQAGESSTMKVIRQTLSEEIGVPPEELTGTANLGEMGMDSLLSLT
VLGKLRETLDLDLPSDFFIENQTLDDIETALDLKPKAPLPPSPAPVSIPAPVALKTEALI
ESKVVHPPATSILLQGNPKTATKTLFLFPDGSGSATSYASLPKTSPDVCVYGLNCPYMKT
PENLNCGLSDLTAPYVAEIRRRQPKGPYNLGGWSAGGICAYDAARQLVLEEGETVERLIL
LDSPFPIGLEKLPPRLYQFFDSMKIFGEGNAPPPSWLLPHFMAFIDALDAYKAVPYPSDD
PQYRDRLPKTYLIWAKDGVCGKPGDPRPEPAPDGSKDPREMLWLLNDRKDFGPNGWDTLV
GKDKVAAIETISDANHFTMMKGDKAKELSAFLEKAFR
>A0A4R8RZF1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Mycobacteroides salmoniphilum|TrEMBL
MLFRTRVPRRHRTILAVSDHESLLSALRAVADDRNHPSVVHGALSADAQRVGFVFPGQGG
QRPGMGRVFYDAVEAYRNEADRCAALFETRFGQSPLSYLLDDSVPADAGASTVQPALFTQ
MAALAAMWRSYGVTPDVTIGHSQGEIAAAYVSGTVPLSDAVAVVGIRAGIVDTFGSSDYA
MAVAAIDRDACEDIIARRSGWAEVSVLNSASMAGISGDRETIHEIVEYLTAKGIFSRVIP
VRYPAHTSLMNTIGDKVRQELRDSLGDARFQDSPIGCFGATLGEAITPDLPQDQYWFLNL
RNPVRFDRAITAALAQGVDTFVELAEHPTLQLAVQENCAAAVGDRVTSVVGTSTRTATNL
DEFTMNLAAIAVNTPGYGWENLRAEPPGKFALPLRDFPNAPTNDIRLWLPYNETGNNRAE
QVASSTQSIPVRAEPRREPGAQVVLEEWVRLTQRSLRPARPFSVVDPTGDCAQLVSALQV
EAEDQGVPLHLVVAGEVAEDTQSLVIVVPAMPEMDEIDSVTAVSQFFAGGSWLPPLSKLV
SDCWIVTVGGESVTSSDLPPNPVHAAISAGYRTLAMDHPSVTFRHLDLGHGDAQGGTARA
VFMALMTGGESELALRDGVLHVKRLRLADPSEFDAAGNPAHVLITGGTGALGLELCEHYS
QAGAQHITLLSRSGETPSITERLALIRKASTCVVTVATCDVGDAAAMARLADELAHPVDL
IAHAAADFSSTVELDLRAIKAETVVEAFRGKVLGLPNLLSSFARESSCRVVLFSSLAATL
GGRGMLLYAAANRMIDSLATRYRAAGVDCVSVQWGQWDVFEGRDSSDLERLGGLGYRPMN
SAEAIRLGMNGLRQNAIVADFDWARGYATLNAFGHGSALSELAQNITEATPEAPTHHASS
GGRPPRDLISLLAEVIGADQADTIDTTAAMVALGVDSLQALEFRRRVKAEFDYELEVSDL
LGGASINDIIATLEQKASPPAGQRASARPAEPITLDDITQRARATAEKAMPSVLNLDVMH
SARDDLDLFGMHAMMAVLRPALQDGAAHSAADIADRLSFTPRHRWLLNRWLEVLNSHGHL
SHHPDHGYRLDRPLPAPTRARLLDVCQDLGYRSELVEFMEKCNNRLLELGQDRTRVQELL
FPDGDMLTAEAGYRENLISRYLNLAARETVSNMVARLQRDRSPVRILELGAGIGGTTDEV
IAGLSGLPVDYHFTDVSTFFLAAAQERFANNPQLRYGLMNLNTDLSGAERYDIVLGANVI
HNATHIGHSLRQLHDVINPGGAIVFIETCNANYQVLTSLKFLMSAAPGQTHPGQSDIRAG
ERIFLTEGEWNDELSQAGFRPLMVLPEAGHPLHLLDQRVFAAVRD
>A0A379U0T4|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Salmonella diarizonae|TrEMBL
MDLGRLAVNWLREKGARRIALLAPRVDESWLRDVEGGQTRVCRCDVGDAGQLATVLTIWR
PTAGIAGAIHAAGVLADAPLQELDDHQLAAVFAVKAQAANQLLQTLRNHDGRYLILYSSA
AATLARRSERHALACGYLDGWPSSFPPLMRRKRSLSPGAHGEKAVGRPRRKCWRRSPTAV
WAR
>A0A100JFV3|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MAHTEEKLLEYLKRVTADLRRTEHRLHDLEAAGHEPIAVIGMACRLPGGIRSPEDLWDLV
ATGGDAVTPLPGDRDWDLDALYDPDPESTGTSYVREGGFVQDVGGFDAAFFGIGPSEALT
MAPQQRLALETAWEAIERAGIDPLTLRGSDTSTFIGCDGLDYAFGDVEVPDGTTGYLTIG
NSGSVTSGRVAYTLGLEGPAVTVDTACSSSLVSLHLAVRSLRTEECALALAGGTYVMATP
APLIGFSELRGLAPDGRCKPFSAHSDGMGMAEGTGVLLLERLSDARRNGHDVLAVIRGSA
VNQDGASNGLTAPNGPSQERVIQAALADAGLSPEDIDAVEAHGTGTVLGDPIEAGALIAA
YGRGRPAERPLWVGAVKSNIGHTQIAAGVAGVIKTVLALQHEVLPPILHVGVPSGHVEWD
GSGVRLLTEGVEWGRGERVRRAGVSSFGFSGTNAHLILEEAPSVEGAGVSGGEVSGVVPW
VVSARSSGALGEQVRRVGELEASAVEVGWSLVTARSVFEHRAVIVDGDMVSGVAGDIGPG
PVLVFPGQGSQWVGMGAQLLDESPVFADRIAECEQALAPHVGWSLTEVLRDGRELDRVDV
VQPVLWAVMVSLAAVWEGYGVRPAAVIGHSQGEIAAACVAGVLSLQDAARIVAVRSDALR
QLQGRGDMASIGTGPDEVRALIGDERPGVSVAVVNSASSTVISGPPAEVAAVVSEAEARG
LRARLIDVGYASHNAQIDELAGQLEERLSGVRPVAVSDVAFYSTVTAGRIDTDALTAEYW
VTNLREQVRFAETLEALQADGYHLFIEASPHPVLVLPMEETIEAGTVVPTLRRDQGGTKQ
LTLAAAQAFTAGADINWRRWFPTPQHPIDLPTYPFQHHHYWLKRTRPHPPTPGAQPTASE
AQLWRAVEERDLGLLSQTLGPEEGSEEAVQALAPALPVLGSWRRRHQEQATIDSWRYHVT
WTHVPDSGSPELGGDWLLFVSAGQAEHPAVQAVFDALTKHGAADVRLCSVEPRTDLAPVR
TDGLAGIVNLLALDEDPHPDHPAVPSGLAATIALVQALGDTGVPLYTVTQGAVSTSAADP
LGRPVQAQVWGLGRVAALEYPRLWGGLVDLPARIDHRTLPRLAAALSPQDEDQIAVRSDG
VHVRRLAHADPVGIEASWRPEGTTLITGGTGGIGAVLARWLAHQGAPHLHLTSRRGPDAP
GAHQLTTELTDLGTHVTVTACDVSNRQQLRDLIDTHPPTAIIHAAGAADLTPIGELTAAH
LGGVLGAKAHAAWNLHELTRGLDLSAFVMFSSGAAVWGSGQQGAYGAANHFLDALAEHRR
AQGLAATSVAWGPWAEAGMSAGEESLAYFKRFGLLPLGSELCVKALHQAISSGRPTLTVA
DFDWARFTPTFTAQRPSPFLADLPENRRAAEGGGSDAELSAFRAELEKTPAAQRQDFLVR
QVRAYAAATLGRAVEEVPAVKPFQELGFDSLTAVQLRNQLNSATGLALPPTVVFDHPTSE
ALATYLREQLGVEGEAGEGQVLTALDKWATAYDAAGLDEAARRRVVGRLRALVSKWSPAA
DGSENGGHDDLEKASADDIFDLISSEFGKS
>A0A1Q2ZMJ0|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces acidiscabies|TrEMBL
MRKALALSGVQPGGESALRSRLAGLGERERARALLDLVRREAAVTLGFDNADALPQGRAF
RDVGFDSLTAVELRNKLASATGLVLPASLVFDYPTPAALAEHLGSELLGTVEAAPVTPVI
TAALDEPIAIVGMGCRFPGGVSSPEQLWNAVVSSVDAMSEFPADRGWDLVGDGFARVGGF
VEDVAGFDAGFFGISPREALAMDPQQRLLLETAWEALERTGIAPNALKGSKTGVFVGGAV
SGYETVGNVSDEADGYRITGGASSVLSGRIAYVLGLEGPAVTVDTACSSSLVALHLAAQA
LRSGECDLALTGGVAVMATPGAFAEFATQGVLAGDGRCKSFAASADGTGWGEGAGLLVVE
RLSDARRNGHRVLAVVRSSAINQDGASNGLSAPNGPSQQRVIRQALASAGLTTAEVDVVE
AHGTGTRLGDPIEAQALLATYGQDRPEDRPLWLGSLKSNIGHTQAAAGVAGVIKMVLAMQ
HGQLPRTLHVDEPTPEVDWSAGAVELLTEQRPWPVVDRPWRAGVSSFGVSGTNAHVILEQ
APELEPASRVEAEPSVVPWVLSARSESALRDQARRLAAHMEADPELDPVDVGAALVSTRA
GLEHRAVVLGTDRDELIARLTGLATGEPGTGVVTGIAGQTGEREVVFVFPGQGAQWTGMA
QELLAASPVFAERMAECAQALAPFVDWDLLEALEDQEALGRVEVVQPVLWAVMVSLAQVW
QSLGVTPAAVMGHSQGEIAAACVAGGLSLADAARIIAVRSRLLAKSLSGRGGMVSVRLPR
AEAESLITRWEGRLSIAAVNGPSWVVVSGDAEAVTELVVAGEAEDFRTRRMDTDCAGHSP
QVDEIKAELIEALADIAPMEGTVAFYSTVTGELTDTRDLDAEYWYRNARETVRLAETTPV
LATAGYEMFVEVSPHPVLTPSLEETLFESHPAAVVTGTLRRGENEPEQLLTALSTLHTHG
VPVDWSAIVGQDSTVELPTYAFQHQRYWPRPRTVAGDARGMGLTSVGHPLLGAAVELAGG
EGVVFTNRLSLTSHAWLADHTARGVVLLAGTAFVELVVRAGDEVGCGVLEDLALERPLVL
SERGAVQVQVVVEAPAESGRRAVSVYSRPEETGTEAGWTRHASGTLTSEAGAPSGVELTV
WPPAGAEPVPVDGFYEALAETGYGYGPAFQGVRTVWRRGEEVFAEVRLPDEVAERAGEFG
IHPALFDAALHAAAFLPAGGEGGLPFSWSGVSLHASGARSLRVRLSETDDGALCLNAADD
TGAPVLSVDSLTLRPLRAELLDGDAQRSLFSVDWTLKPAVPTGTENSPRCVVAGAGGQDL
AKMLGVAWYPELSECPETDLVLLPTGADADDGDVAAAARSEVCRVLELVQEWVADERGDA
RLVVVTRNAVSTGTGDRVEDMAGVQGLVRSARSEHPGRFGLVDVDGSAESWQCLPAVLSE
TTDDEGDFELAVRAGQAYTPRLTRTREVLTAPMETWRLGMTGQGSVDDLVLEPSPEAEVP
LEAGQVRIGVRAAGLNFRDVLNVLGVYPGEAPLLGAEVAGVVLEAGPGVTGFVPGDRVMG
MAVGGFGPVVAADARLIVPIPRGWSFAQAAGVPVVFLTALYGLRETGRLTAGQRVLVHAA
AGGVGMAAVQLARLWGAEVFATASPGKQDTVYGLGVARDHIASSRTTEFADRFTGMDVVL
NSLAGEFIDASLNVLRDGGRFVELGKTDLRDTDAIATTHPGVSYHAIDLEIDLDVVGGML
AELAELFESGVLSPLPTRTWDVRQSRDAFRYMAQARHVGKIVLTVPQQLDPDRTVLITGG
TGGLGGLLARHLADRHGIRHLTLVSRQGIAAPGAQELVEELTALGAQVRVVACDVSDRNA
VTELIAGVPQQHPLTAVIHAAAVLDDGTITSLTPERIDTVMRPKADAAWYLHEATAGLDL
AAFILFSSFSATSGAPGQGNYAAANAFLDALALHRQVQGLPAASLAWGWWADTSSMTGLG
HTDHARFGRAGVRAMPAAEGLALFDLACRRPEAYLVPVGLELPRNGGSVPPLLRGLVASG
PARPVARAGVQDSSGLVRRLAGLTAADQQRLLLDLVCGHVATVLGHASVEAVDPEKALRD
MGFDSLTTVELRNRLAAATGLRLPATLAFDHPTTSRLATHLRQQLLGTVEAVSVTPVTTA
ALDEPIAIVGMGCRFPGGVESPEQLWTLLTGGIDTISAFPTQRGWDLTGDGATQTGGFLK
DVAGFDAGFFGISPREALVMDPQQRLLLETAWEALERSGIDPNTLKGSRTGVFVGGTGSG
YDTVGDAADQVDGYLLTGAASSVLSGRIAYTLGLEGPAVTVDTACSSSLVALHLAAQALR
SGECSMALAGGVTVMATPGVFIAGSAMQGGVGGDGRCKAFAATADGFGVAEGAGLLVVER
LSDARRNGHRVLAVVRGSAINQDGASNGLTAPNGPSQQRVIRQALASAGVPTTEVDVVEA
HGTGTRLGDPIEAQALLATYGQDRSEDRPLWLGSVKSNLGHTQAAAGVAGVIKMVLAMQH
GQLPRTLHVDEPTPEVDWSAGAVELLTEQQPWPAVDRPWRAGVSSFGISGTNAHVILEQA
PDQAPDLEPAPDVEVVPWVLSARSESALRDQARRLLAHVEANPELDPVDVGAALVSTRAS
FGHRAVVLGTDRDQLIAGLAGLAAGEPGAGVASGVSAASGRTAFLFTGQSAQRLEMGREL
AAEFPVFAEAFDEVRARFAEWLPGSPEPAATDDGLADPAWAQAALFAFEVAMFRLLSSWG
VTPDYVAGHATGEAVAAYVAGAWSLDDARRVLTAGHDENGTAPTESPGPSRIVLVSLESG
EPVQERPEFAVADTQRPARFAEAVVWLREQGATRFVELGPDATLTGLRPDGVDAEFVAMQ
CQDRPQVYEAMAALASLYTRGVTVDWRAMFPRSGARRVELPTYAFQRERFWSLASGTGGV
AGAGLSTAGHALLGAVVRLADRDELVFTSRLSQATHPWLAEHHLGATAVLPVTALVDIAM
RAGDEAGCAVLEELTVHAPLVIPDHGAVQVQVVVGSPDEEGRRPIAVYARPENTDDEWLS
YATGLLAALGGEPGWTERTWPPADARPVPVEDAYDLLAERGHRYGPVFQGLRAVWRRGDV
VFAEVALPQRAAGESARFGIHPALLDAALHPLLIASEDVRLPSTWTNVSLHTTGTTALRV
VLTPAGDDDGYRLDVADEVGNAVATARLSRWERVSTGQRGVEDDLLRVEWAPVGSLEDTG
EHEDSVALLGEVSSELAEAGFLRFGDITEAALSYEPWDILVAESPADGELPSVAHRAVRH
VLTRLQEWVTRDDLPDNRLVVVTRGAVAASEGEAVVDLAGAAVWGLVRSAQSEHPDRITL
VDIPDGGSVPWARIAAAAAIEPQLAVRDGEVLVPRLVRTTGGGTARPSQAGQGTVLVTGG
TGALGALFARHLVTRHGVRHLVLASRRGAQAPQADVLRETLAELGAQVEFVACDVADRES
VAHLLAGIGEEHPLVGVVHAAGALDDGVVTSLTGERVTEVLRAKADGAWHLHELTQHLDL
DLFVLFSSVSGVLGIPGQANYAAANAFLDGVAEHRRARALPAVSLAWGLFDDTAGAAKQL
GLKPITTETAVRLFDQALHDGPAAVVPALLDLGRLGQESVRVPTLLRSLLPARATRGTGS
VAEESLTERLAGMPRSEAEQYVRDLVRRETATALGYASAGEVAPEVSFRDAGFDSLAAVR
FRNQLVDKTGLALPTTLVFDHTSPAVLADHLVGRLVVTGESPERAVLAELDRLEAVLMSM
PGGDPETEAIGSRLDAVVSRWRTAFRPSGTDDHAETVTKLQDATEEEVLDFIDRQFRRDE
R
>A0A4U9U9U1|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Serratia fonticola|TrEMBL
MSSNAQLPENMKVIEISQPGEPEVLVSAERPLPVLAQGEILVKVAAAGVNRPDVMQRRGQ
YAPPPGASDIPGLEIAGTVVAVGVGVQRYAPGDAVCALIAGGGYAEYCKVHESNALPVPQ
GFSMIEAAAMPETFFTVWVNVFQRGHLRAGKPC
>A0A1C3P5N7|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Candidatus Frankia californiensis|TrEMBL
MRVSLPASGGDWSSELAAWDGEAVERRLSEALSTAGRIDLCLTILGGSETRDHSVRQDTW
DHSVRQLADAVLVAKHASVPLAAAARSDDRAAFVTVTRLDGGLGHRGGRQAAEALLGGVG
GVVKTLAHEEPSIFCRALDIDPALGDDDALAVLLDEVRDAAVDTLEVGVDAARGRWTVAP
GPYGSPRASTATAVAGVTTGPVPPASTVGAGDVFVVTGGARGVTASCVRALGEHSQVEFL
LLGRTALTAEPDWAAGVAEGDLKRAAIAALGAGGGKPPTPRQVDAVLRDIQAQREIRSTL
DALAGTGSSAAASYIQVDVGDAAAVRDALSAHRDRITGVVHGAGTLADGLVRTKTPDDVR
RVFTPKLAGLRNVLDALDGAPVRHIVLFTSVAGLFGNAGQADYAAANEALCRVAASLKHE
HPDRHVTAIDWGAWDGGMVAADLREVFRARGVELLAPATGARMFVEQFSPDHADDVCVLV
GQSKALTDGTGPRPARAFVARRDLTGIEDTEVLQAHRIDAFPVLPATFGLGWLVNVLERA
HPGLQVIESRGFEVHKGIVFDGAQGREYQVEVPLAESRDGRLTVRAGVRAAGGSGLPISH
YVGTFVLAEAPPAAPTGPGRPGEAVGSGPEDGLEIYTGGTLFHGPALQGIRRILQRRDDR
VVLECRLADQAVAGGAFAGALHSPVLADILLHGPSVLGRWLTGLACLPLAVGRWEYFAPL
PDGDPFVVVLDEVRRAASSITVTVTASGPGGRVLQRLTDVSMIGTPDMAAKFAAAVQWWL
PGEGA
>O54593|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Amycolatopsis mediterranei|TrEMBL
MATDEKLLKYLKRVTAELHSLRKQGARHADEPLAVVGMACRFPGGVSSPEDLWQLVAGGV
DALSDFPDDRGWELDGLFDPDPDHPGTSYTSQGGFLRGAGLFDAGLFGISPREALVMDPQ
QRVLLETSWEALEDAGVDPLSLKGSDVGVFSGVFTQGYGAGAITPDLEAFAGIGAASSVA
SGRVSYVFGLEGPAVTIDTACSSSLVAIHLAAQALRAGECSMALAGGATVMPTPGTFVAF
SRQRVLAADGRSKAFSSTADGTGWAEGAGVLVLERLSVAQERGHRILAVLRGSAVNQDGA
SNGLTAPNGPSQQRVIRKALAGAGLVASDVDVVEAHGTGTALGDPIEAQALLATYGQGRE
RPLWLGSVKSNFGHTQAAAGVAGVIKMVQALRHGAMPPTLHVAEPTPEVDWSAGAVELLT
EPREWPAGDRPRRAGVSAFGISGTNAHLILEEAPPADAVAEEPEFKGPVPLVVSAGSPTS
LAAQAGRLAEVLASGGVSRARLASGLLSGRALLGDRAVVVAGTDEDAVAGLRALARGDRA
PGVLTGSAKHGKVVYVFPGQGSQRLGMGRELYDRYPVFATAFDEACEQLDVCLAGRAGHR
VRDVVLGEVPAETGLLNQTVFTQAGLFAVESALFRLAESWGVRPDVVLGHSIGEITAAYA
AGVFSLPDAARIVAARGRLMQALAPGGAMVAVAASEAEVAELLGDGVELAAVNGPSAVVL
SGDADAVVAAAARMRERGHKTKQLKVSHAFHSARMAPMLAEFAAELAGVTWREPEIPVVS
NVTGRFAEPGELTEPGYWAEHVRRPVRFAEGVAAATESGGSLFVELGPGAALTALVEETA
EVTCVAALRDDRPEVTALITAVAELFVRGVAVDWPALLPPVTGFVDLPKYAFDQQHYWLQ
PAAQATDAASLGQVAADHPLLGAVVRLPQSDGLVFTSRLSLKSHPWLADHVIGGVVLVAG
TGLVELAVRAGDEAGCPVLEELVIEAPLVVPDHGGVRIQVVVGAPGETGSRAVEVYSLRE
DAGAEVWARHATGFLAATPSQHKPFDFTAWPPPGVERVDVEDFYDGLVDRGYAYGPSFRG
LRAVWRRGDEVFAEVALAEDDRADAARFGIHPGLLDAALHAGMAGATTTEEPGRPVLPFA
WNGLVLHAAGASALRVRLAPSGPDALSVEAADEAGGLVVTADSLVSRPVSAEQLGAAANH
DALFRVEWTEISSAGDVPADHVEVLEAVGEDPLELTGRVLEAVQTWLADAADDARLVVVT
RGAVHEVTDPAGAAVWGLIRAAQAENPDRIVLLDTDGEVPLGRVLATGEPQTAVRGATLF
APRLARAEAAEAPAVTGGTVLISGAGSLGALTARHLVARHGVRRLVLVSRRGPDADGMAE
LTAELIAQGAEVAVVACDLADRDQVRVLLAEHRPNAVVHTAGVLDDGVFESLTRERLAKV
FAPKVTAANHLDELTRELDLRAFVVFSSASGVFGSAGQGNYAAANAYLDAVVANRRAAGL
PGTSLAWGLWEQTDGMTAHLGDADQARASRGGVLAISPAEGMELFDAAPDGLVVPVKLDL
RKTRAGGTVPHLLRGLVRPGRQQARPASTVDNGLAGRLAGLAPAEQEALLLDVVRTQVAL
VLGHAGPEAVRADTAFKDTGFDSLTSVELRNRLREASGLKLPATLVFDYPTPVALARYLR
DELGDTVATTPVATAAAADAGEPIAIVGMACRLPGGVTDPEGLWRLVRDGLEGLSPFPED
RGWDLENLFDDDPDRSGTTYTSRGGFLDGAGLFDAGFFGISPREALAMDPQQRLLLEAAW
EALEGTGVDPGSLKGADVGVFAGVSNQGYGMGADPAELAGYASTAGASSVVSGRVSYVFG
FEGPAVTIDTACSSSLVAMHLAGQALRQGECSMALAGGVTVMGTPGTFVEFAKQRGLAGD
GRCKAYAEGADGTGWAEGVGVVVLERLSVARERGHRVLAVLRGSAVNSDGASNGLTAPNG
PSQQRVIRRALAGAGLEPSDVDIVEGHGTGTALGDPIEAQALLATYGKDRDPETPLWLGS
VKSNFGHTQSAAGVAGVIKMVQALRHGVMPPTLHVDRPTSQVDWSAGAVEVLTEAREWPR
NGRPRRAGVSSFGISGTNAHLIIEEAPAEPQLAGPPPDGGVVPLVVSARSPGALAGQARR
LATFLGDGPLSDVAGALTSRALFGERAVVVADSAEEARAGLGALARGEDAPGLVRGRVPA
SGLPGKLVWVFPGQGTQWVGMGRELLEESPVFAERIAECAAALEPWIGWSLFDVLRGDGD
LDRVDVLQPACFAVMVGLAAVWSSAGVVPDAVLGHSQGEIAAACVSGALSLEDAAKVVAL
RSQAIAAKLSGRGGMASVALGEADVVSRLADGVEVAAVNGPASVVIAGDAQALDETLEAL
SGAGIRARRVAVDYASHTRHVEDIEDTLAEALAGIDARAPLVPFLSTLTGEWIRDEGVVD
GGYWYRNLRGRVRFGPAVEALLAQGHGVFVELSAHPVLVQPITELTDETAAVVTGSLRRD
DGGLRRLLTSMAELFVRGVEVDWTSLVPPARADLPTYAFDHEHYWLRAADTASDAVSLGL
AGADHPLLGAVVQLPQSDGLVFTSRLSLRSHPWLADHAVRDVVIVPGTGLVELAVRAGDE
AGCPVLDELVIEAPLVVPRRGGVRVQVALGGPADDGSRTVDVFSLREDADSWLRHATGVL
VPENRPRGTAAFDFAAWPPPEAKPVDLTGAYDVLADVGYGYGPTFRAVRAVWRRGSGNTT
ETFAEIALPEDARAEAGRFGIHPALLDAALHSTMVSAAADTESYGDEVRLPFAWNGLRLH
AAGASVLRVRVAKPERDSLSLEAVDESGGLVVTLDSLVGRPVSNDQLTTAAGPAGAGSLY
RVDWTPLSSVDTSGRVPSWLPVATAEEVATLADDVLTGATEAPAVAVMEAVADEGSVLAL
TVRVLDVVQCWLAGGGLEGTKLAIVTRGAVPAGDGVVHDPAAAAVWGLVRAAQAENPDRI
VLLDVEPEADVPPLLGSVLADGEPQVAVRGTTLSIPRLARAARPDPAAGFKTRGPVLVTG
GTGSLGGLVARHLVERHGVRQLVLASRRGLDAEGAKDLVTDLTALGADVAVAACDVADRD
QVAALLTEHRPSAVVHTAGVPDAGVIGTVTPDRLAEVFAPKVTAARHLDELTRDLDLDSF
VVYSSVSAVFMGAGSGSYAAANAYLDGLMAHRRAAGLPGQSLAWGLWDQTTGGMAAGTDE
AGRARMTRRGGLVAMKPAAGLDLFDAAIGSGEPLLVPAQLDLRGLRAEAAGGTEVPHLLR
GLVRAGRQQARAASTVEENWAGRLAGLEPAERGQVLLELVRAQVAGVLGYRAAHQVDPDQ
GLFEIGFDSLTAIELRNRLRARTERKISPGVVFDHPTPALLAAHLNELLRKKV
>Q5UNP6|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Saccharopolyspora erythraea|TrEMBL
MADLSKLSDSRTAQPGRIVRPWPLSGCNESALRARARQLRAHLDRFPDAGVEGVGAALAH
DEQADAGPHRAVVVASSTSELLDGLAAVADGRPHASVVRGVARPSAPVVFVFPGQGAQWA
GMAGELLGESRVFAAAMDACARAFEPVTDWTLAQVLDSPEQSRRVEVVQPALFAVQTSLA
ALWRSFGVTPDAVVGHSIGELAAAHVCGAAGAADAARAAALWSREMIPLVGNGDMAAVAL
SADEIEPRIARWDDDVVLAGVNGPRSVLLTGSPEPVARRVQELSAEGVRAQVINVSMAAH
SAQVDDIAEGMRSALAWFAPGGSEVPFYASLTGGAVDTRELVADYWRRSFRLPVRFDEAI
RSALEVGPGTFVEASPHPVLAAALQQTLDAEGSSAAVVPTLQRGQGGMRRFLLAAAQAFT
GGVAVDWTAAYDDVGAEPGSLPEFAPAEEEDEPAESGVDWNAPPHVLRERLLAVVNGETA
ALAGREADAEATFRELGLDSVLAAQLRAKVSAAIGREVNIALLYDHPTPRALAEALAAGT
EVAQRETRARTNEAAPGEPVAVVAMACRLPGGVSTPEEFWELLSEGRDAVAGLPTDRGWD
LDSLFHPDPTRSGTAHQRGGGFLTEATAFDPAFFGMSPREALAVDPQQRLMLELSWEVLE
RAGIPPTSLQASPTGVFVGLIPQEYGPRLAEGGEGVEGYLMTGTTTSVASGRIAYTLGLE
GPAISVDTACSSSLVAVHLACQSLRRGESSLAMAGGVTVMPTPGMLVDFSRMNSLAPDGR
CKAFSAGANGFGMAEGAGMLLLERLSDARRNGHPVLAVLRGTAVNSDGASNGLSAPNGRA
QVRVIQQALAESGLGPADIDAVEAHGTGTRLGDPIEARALFEAYGRDREQPLHLGSVKSN
LGHTQAAAGVAGVIKMVLAMRAGTLPRTLHASERSKEIDWSSGAISLLDEPEPWPAGARP
RRAGVSSFGISGTNAHAIIEEAPQVVEGERVEAGDVVAPWVLSASSAEGLRAQAARLAAH
LREHPGQDPRDIAYSLATGRAALPHRAAFAPVDESAALRVLDGLATGNADGAAVGTSRAQ
QRAVFVFPGQGWQWAGMAVDLLDTSPVFAAALRECADALEPHLDFEVIPFLRAEAARREQ
DAALSTERVDVVQPVMFAVMVSLASMWRAHGVEPAAVIGHSQGEIAAACVAGALSLDDAA
RVVALRSRVIATMPGNKGMASIAAPAGEVRARIGDRVEIAAVNGPRSVVVAGDSDELDRL
VASCTTECIRAKRLAVDYASHSSHVETIRDALHAELGEDFHPLPGFVPFFSTVTGRWTQP
DELDAGYWYRNLRRTVRFADAVRALAEQGYRTFLEVSAHPILTAAIEEIGDGSGADLSAI
HSLRRGDGSLADFGEALSRAFAAGVAVDWESVHLGTGARRVPLPTYPFQRERVWLEPKPV
ARRSTEVDEVSALRYRIEWRPTGAGEPARLDGTWLVAKYAGTADETSTAAREALESAGAR
VRELVVDARCGRDELAERLRSVGEVAGVLSLLAVDEAEPEEAPLALASLADTLSLVQAMV
SAELGCPLWTVTESAVATGPFERVRNAAHGALWGVGRVIALENPAVWGGLVDVPAGSVAE
LARHLAAVVSGGAGEDQLALRADGVYGRRWVRAAAPATDDEWKPTGTVLVTGGTGGVGGQ
IARWLARRGAPHLLLVSRSGPDADGAGELVAELEALGARTTVAACDVTDRESVRELLGGI
GDDVPLSAVFHAAATLDDGTVDTLTGERIERASRAKVLGARNLHELTRELDLTAFVLFSS
FASAFGAPGLGGYAPGNAYLDGLAQQRRSDGLPATAVAWGTWAGSGMAEGPVADRFRRHG
VIEMPPETACRALQNALDRAEVCPIVIDVRWDRFLLAYTAQRPTRLFDEIDDARRAAPQA
AAEPRVGALASLPAPEREKALFELVRSHAAAVLGHASAERVPADQAFAELGVDSLSALEL
RNRLGAATGVRLPTTTVFDHPDVRTLAAHLAAELGGATGAEQAAPATTAPVDEPIAIVGM
ACRLPGEVDSPERLWELITSGRDSAAEVPDDRGWVPDELMASDAAGTRRAHGNFMAGAGD
FDAAFFGISPREALAMDPQQRQALETTWEALESAGIPPETLRGSDTGVFVGMSHQGYATG
RPRPEDGVDGYLLTGNTASVASGRIAYVLGLEGPALTVDTACSSSLVALHTACGSLRDGD
CGLAVAGGVSVMAGPEVFTEFSRQGALSPDGRCKPFSDEADGFGLGEGSAFVVLQRLSDA
RREGRRVLGVVAGSAVNQDGASNGLSAPSGVAQQRVIRRAWARAGITGADVAVVEAHGTG
TRLGDPVEASALLATYGKSRGSSGPVLLGSVKSNIGHAQAAAGVAGVIKVLLGLERGVVP
PMLCRGERSGLIDWSSGEIELADGVREWSPAADGVRRAGVSAFGVSGTNAHVIIAEPPEP
EPVPQPRRMLPATGVVPVVLSARTGAALRAQAGRLADHLAAHPGIAPADVSWTMARARQH
FEERAAVLAADTAEAVHRLRAVADGAVVPGVVTGSASDGGSVFVFPGQGAQWEGMARELL
PVPVFAESIAECDAVLSEVAGFSVSEVLEPRPDAPSLERVDVVQPVLFAVMVSLARLWRA
CGAVPSAVIGHSQGEIAAAVVAGALSLEDGMRVVARRSRAVRAVAGRGSMLSVRGGRSDV
EKLLADDSWTGRLEVAAVNGPDAVVVAGDAQAAREFLEYCEGVGIRARAIPVDYASHTAH
VEPVRDELVQALAGITPRRAEVPFFSTLTGDFLDGTELDAGYWYRNLRHPVEFHSAVQAL
TDQGYATFIEVSPHPVLASSVQETLDDAESDAAVLGTLERDAGDADRFLTALADAHTRGV
AVDWEAVLGRAGLVDLPGYPFQGKRFWLLPDRTTPRDELDGWFYRVDWTEVPRSEPAALR
GRWLVVVPEGHEEDGWTVEVRSALAEAGAEPEVTRGVGGLVGDCAGVVSLLALEGDGAVQ
TLVLVRELDAEGIDAPLWTVTFGAVDAGSPVARPDQAKLWGLGQVASLERGPRWTGLVDL
PHMPDPELRGRLTAVLAGSEDQVAVRADAVRARRLSPAHVTATSEYAVPGGTILVTGGTA
GLGAEVARWLAGRGAEHLALVSRRGPDTEGVGDLTAELTRLGARVSVHACDVSSREPVRE
LVHGLIEQGDVVRGVVHAAGLPQQVAINDMDEAAFDEVVAAKAGGAVHLDELCSDAELFL
LFSSGAGVWGSARQGAYAAGNAFLDAFARHRRGRGLPATSVAWGLWAAGGMTGDEEAVSF
LRERGVRAMPVPRALAALDRVLASGETAVVVTDVDWPAFAESYTAARPRPLLDRIVTTAP
SERAGEPETESLRDRLAGLPRAERTAELVRLVRTSTATVLGHDDPKAVRATTPFKELGFD
SLAAVRLRNLLNAATGLRLPSTLVFDHPNASAVAGFLDAELGTEVRGEAPSALAGLDALE
AALPEVPATEREELVQRLERMLAALRPVAQAADASGTGANPSGDDLGEAGVDELLEALGR
ELDGD
>B6ZK67|6-deoxyerythronolide-B synthase|EC 2.3.1.94|Streptomyces lasalocidi|TrEMBL
MADVVNTEDRLRDYLKRATADLSRVRRQLQETEAASREPIAIIGMACRLPGGVDSPEGLW
ELVDSGTDAIAGFPLDRGWDVEGMYDPDAEAPGKTYVKEAGFLYDAGEFDAGFFGISPRE
AVSMDPQQRLMLEASWEAFERAGLDPARQRGTATGVFVGATATGYVSPAAEVPEGAEGFA
ITGNMTAVTSGRISYTLGLQGPAVTIDTACSSSLVALHLACQSLRQGECTTALAGGVTVM
PTPTAFTEFSRQRGLAPDGRCKSFAAAADGTNWAEGVAVLVVERLSDARRNGHRVLAVVR
GTAINQDGASNGLSAPNDLAQERVIRSALDNAGLTASDVDAVEAHGTGTTLGDPIEAQAL
LAAYGHERPAHRPLRVGSLKSNIGHAGPAAGVAGVIKMVMAMRHGVLPRSLHIDEPTPQV
DWSSGAVTLLTEPVDWPDSDRPRRAGVSAFGISGTNAHVILEQAPTQDPQQPAPPVPAAP
WLLSAKTPAALRAQARRLHTHLARHPHPDPTDIAHALATTRTPHEHRAALVTDDHGTRGP
ALAALAEGAPDACLISGTALSKGRTVFVFPGQGSQWTGMGRELLHTSPEFAAYIAECETA
LNDFVDWSLTDVLRGTEGAPGYDRVDVVQPALFAVMVSLARLWQHHGIHPDAVIGHSQGE
IAAAHIAGALSLQDAARIVALRSQALLPLAGLGGMTSLALPHDQALQLIQPWGQDLSIAS
VNGPHSTVVSGTTHALDELHTTCDTQGVRARRIPVDYASHSAQVESIRDTVLQAATGINP
QPTTIPLYSTVTGQPIDGTQLDADYWYTNLRHTVRFEETTRALLGSGHRHFIETTAHPVL
ALALEETIEATGSDARVTGTLRRDHGDLTQLHTALATAWTHGIDVDWTAVLGDRRTPFEL
PTYAFQRQRYWLEPGAGVGVPVGGTSAEARFWDAVEDEDLEALVAAIGADGDDASWAGVL
PALAGWRRRQREQSALDDLRYKVTWKPTAVADGASATGTWLVVVPESLAGGGWPVVVARA
VDQAGGRPVVLSVDAADGADRSRLGLRIHEALGEGPVPDAVVSLLALDPSALPGLPDVPQ
ALASTAALVQALLDLGLEARLWCVTSGAVSVSGADGPSAPEQAAVWGFGRVAGLEHPHLW
AGLVDLPPEADERTAARLVGVLAGAGGEDQVALRSSGVFVRRLVRAPASEVPAVRSWKPG
GTVLVTGGTGGLGRQVARWLARGGADHLLLVSRRGVDAPGADELVDELTDLGARVTVAAC
DVADRDAVQRLLSEQVPSDAPLTAVIHTAAVLDDGVIDSLSPERMEQVLRVKVGGAVHLY
ELTRESDLSAFVLFSSFGSTFGLPGLGNYAPGNAALEALAEQWRAEGRPATAVGWGTWAG
GGMADGGVGERGRTHGIHELEPALATAALEQALERDESSPVIIDIDWERFAVAFHAKRPT
RGFELVPEAQAALEAADGGPGPDGGAGDPSELLDRLAALPDAERDRALLEVVRGNAASVM
SHGAMRTATLEAVEPTRAFRDLGFDSLMAVELRNRIGAATGLRLAPTLVFDHPTPEAVVR
HLRAELGLEGDGAPDPVFDELDGLERALSSYTPDTDTRVKITKRLESLLWEWTRSEADAP
DPVDAADLAAVSDDEMFELIDRELGSA