Sequence of PPB1_HUMAN

alkaline phosphatase

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Nucleotide sequence of the human placental alkaline phosphatase gene. Evolution of the 5' flanking region by deletion/substitution.

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Millan J.L.

Molecular cloning and sequence analysis of human placental alkaline phosphatase.

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Henthorn P.S.,Knoll B.J.,Raducha M.,Rothblum K.N.,Slaughter C.,Weiss M.,Lafferty M.A.,Fischer T.,Harris H.

Products of two common alleles at the locus for human placental alkaline phosphatase differ by seven amino acids.

Proc. Natl. Acad. Sci. U.S.A.

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Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

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The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

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344533

Kam W.,Clauser E.,Kim Y.S.,Kan Y.W.,Rutter W.J.

Cloning, sequencing, and chromosomal localization of human term placental alkaline phosphatase cDNA.

Proc. Natl. Acad. Sci. U.S.A.

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344534

Ezra E.,Blacher R.,Udenfriend S.

Purification and partial sequencing of human placental alkaline phosphatase.

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1983

344535

Ovitt C.E.,Strauss A.W.,Alpers D.H.,Chou J.Y.,Boime I.

Expression of different-sized placental alkaline phosphatase mRNAs in placenta and choriocarcinoma cells.

Proc. Natl. Acad. Sci. U.S.A.

83

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1986

344536

Micanovic R.,Bailey C.A.,Brink L.,Gerber L.,Pan Y.C.E.,Hulmes J.D.,Udenfriend S.

Aspartic acid-484 of nascent placental alkaline phosphatase condenses with a phosphatidylinositol glycan to become the carboxyl terminus of the mature enzyme.

Proc. Natl. Acad. Sci. U.S.A.

85

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1988

344537

Micanovic R.,Gerber L.D.,Berger J.,Kodukula K.,Udenfriend S.

Selectivity of the cleavage/attachment site of phosphatidylinositol-glycan-anchored membrane proteins determined by site-specific mutagenesis at Asp-484 of placental alkaline phosphatase.

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87

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1990

344538

Watanabe T.,Wada N.,Kim E.E.,Wyckoff H.W.,Chou J.Y.

Mutation of a single amino acid converts germ cell alkaline phosphatase to placental alkaline phosphatase.

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1991

344539

Lowe M.E.

Site-specific mutations in the COOH-terminus of placental alkaline phosphatase: a single amino acid change converts a phosphatidylinositol-glycan-anchored protein to a secreted protein.

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1992

344540

Kozlenkov A.,Manes T.,Hoylaerts M.F.,Millan J.L.

Function assignment to conserved residues in mammalian alkaline phosphatases.

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Dephoure N.,Zhou C.,Villen J.,Beausoleil S.A.,Bakalarski C.E.,Elledge S.J.,Gygi S.P.

A quantitative atlas of mitotic phosphorylation.

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2008

344542

Hoylaerts M.F.,Van Kerckhoven S.,Kiffer-Moreira T.,Sheen C.,Narisawa S.,Millan J.L.

Functional significance of calcium binding to tissue-nonspecific alkaline phosphatase.

PLoS ONE

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2015

344543

Le Du M.H.,Stigbrand T.,Taussig M.J.,Menez A.,Stura E.A.

Crystal structure of alkaline phosphatase from human placenta at 1.8 A resolution. Implication for a substrate specificity.

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344544

Llinas P.,Stura E.A.,Menez A.,Kiss Z.,Stigbrand T.,Millan J.L.,Le Du M.H.

Structural studies of human placental alkaline phosphatase in complex with functional ligands.

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344545

Llinas P.,Masella M.,Stigbrand T.,Menez A.,Stura E.A.,Le Du M.H.

Structural studies of human alkaline phosphatase in complex with strontium: implication for its secondary effect in bones.

Protein Sci.

15

1691-1700

2006

344546

Stec B.,Cheltsov A.,Millan J.L.

Refined structures of placental alkaline phosphatase show a consistent pattern of interactions at the peripheral site.

Acta Crystallogr. F

66

866-870

2010