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Sequence of ABEC1_HUMAN

EC Number:3.5.4.36

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
mRNA(cytosine6666) deaminase
P41238
Homo sapiens
236
28192
Reaction
cytosine6666 in apolipoprotein B mRNA + H2O = uracil6666 in apolipoprotein B mRNA + NH3
Other sequences found for EC No. 3.5.4.36

General information:

Sequence
show sequence in fasta format
  0 MTSEKGPSTG DPTLRRRIEP WEFDVFYDPR ELRKEACLLY EIKWGMSRKI WRSSGKNTTN
 60 HVEVNFIKKF TSERDFHPSM SCSITWFLSW SPCWECSQAI REFLSRHPGV TLVIYVARLF
120 WHMDQQNRQG LRDLVNSGVT IQIMRASEYY HCWRNFVNYP PGDEAHWPQY PPLWMMLYAL
180 ELHCIILSLP PCLKISRRWQ NHLTFFRLHL QNCHYQTIPP HILLATGLIH PSVAWR
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
510415
Hadjiagapiou C.,Giannoni F.,Funahashi T.,Skarosi S.F.,Davidson N.O.
Molecular cloning of a human small intestinal apolipoprotein B mRNA editing protein.
Nucleic Acids Res.
22
1874-1879
1994
510416
Lau P.P.,Zhu H.-J.,Baldini A.,Charnsangavej C.,Chan L.
Dimeric structure of a human apolipoprotein B mRNA editing protein and cloning and chromosomal localization of its gene.
Proc. Natl. Acad. Sci. U.S.A.
91
8522-8526
1994
510417
Hirano K.,Min J.,Funahashi T.,Baunoch D.A.,Davidson N.O.
Characterization of the human apobec-1 gene: expression in gastrointestinal tissues determined by alternative splicing with production of a novel truncated peptide.
J. Lipid Res.
38
847-859
1997
510418
Fujino T.,Navaratnam N.,Scott J.
Human apolipoprotein B RNA editing deaminase gene (APOBEC1).
Genomics
47
266-275
1998
510420
Lau P.P.,Zhu H.J.,Nakamuta M.,Chan L.
Cloning of an Apobec-1-binding protein that also interacts with apolipoprotein B mRNA and evidence for its involvement in RNA editing.
J. Biol. Chem.
272
1452-1455
1997
510421
Lau P.P.,Chang B.-H.,Chan L.
Two-hybrid cloning identifies an RNA-binding protein, GRY-RBP, as a component of apobec-1 editosome.
Biochem. Biophys. Res. Commun.
282
977-983
2001
510422
Mukhopadhyay D.,Anant S.,Lee R.M.,Kennedy S.,Viskochil D.,Davidson N.O.
C-->U editing of neurofibromatosis 1 mRNA occurs in tumors that express both the type II transcript and apobec-1, the catalytic subunit of the apolipoprotein B mRNA-editing enzyme.
Am. J. Hum. Genet.
70
38-50
2002
510423
Sun H.,Samarghandi A.,Zhang N.,Yao Z.,Xiong M.,Teng B.B.
Proprotein convertase subtilisin/kexin type 9 interacts with apolipoprotein B and prevents its intracellular degradation, irrespective of the low-density lipoprotein receptor.
Arterioscler. Thromb. Vasc. Biol.
32
1585-1595
2012