Any feedback?
Please rate this page
(sequences.php)
(0/150)

BRENDA support

Sequence of XGPT_ECOLI

EC Number:2.4.2.22

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
xanthine phosphoribosyltransferase
P0A9M5
Escherichia coli (strain K12)
152
16971
Reaction
XMP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine
Other sequences found for EC No. 2.4.2.22

General information:

Sequence
show sequence in fasta format
  0 MSEKYIVTWD MLQIHARKLA SRLMPSEQWK GIIAVSRGGL VPGALLAREL GIRHVDTVCI
 60 SSYDHDNQRE LKVLKRAEGD GEGFIVIDDL VDTGGTAVAI REMYPKAHFV TIFAKPAGRP
120 LVDDYVVDIP QDTWIEQPWD MGVVFVPPIS GR
Download this sequence
in fasta format
Download all sequences for 2.4.2.22
in fasta format
in csv (Excel, OpenOffice) format
Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
501790
Pratt D.,Subramani S.
Nucleotide sequence of the Escherichia coli xanthine-guanine phosphoribosyl transferase gene.
Nucleic Acids Res.
11
8817-8823
1983
501791
Richardson K.K.,Fostel J.,Skopek T.R.
Nucleotide sequence of the xanthine guanine phosphoribosyl transferase gene of E. coli.
Nucleic Acids Res.
11
8809-8816
1983
501792
Nueesch J.,Schuemperli D.
Structural and functional organization of the gpt gene region of Escherichia coli.
Gene
32
243-249
1984
501793
Jagadeeswaran P.,Ashman C.R.,Roberts S.,Langenberg J.
Nucleotide sequence and analysis of deletion mutants of the Escherichia coli gpt gene in plasmid pSV2 gpt.
Gene
31
309-313
1984
501794
Richardson K.K.,Richardson F.C.,Crosby R.M.,Swenberg J.A.,Skopek T.R.
DNA base changes and alkylation following in vivo exposure of Escherichia coli to N-methyl-N-nitrosourea or N-ethyl-N-nitrosourea.
Proc. Natl. Acad. Sci. U.S.A.
84
344-348
1987
501797
Blattner F.R.,Plunkett G. III,Bloch C.A.,Perna N.T.,Burland V.,Riley M.,Collado-Vides J.,Glasner J.D.,Rode C.K.,Mayhew G.F.,Gregor J.,Davis N.W.,Kirkpatrick H.A.,Goeden M.A.,Rose D.J.,Mau B.,Shao Y.
The complete genome sequence of Escherichia coli K-12.
Science
277
1453-1462
1997
501798
Hayashi K.,Morooka N.,Yamamoto Y.,Fujita K.,Isono K.,Choi S.,Ohtsubo E.,Baba T.,Wanner B.L.,Mori H.,Horiuchi T.
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.
Mol. Syst. Biol.
2
0-0
2006
501799
Mulligan R.C.,Berg P.
Factors governing the expression of a bacterial gene in mammalian cells.
Mol. Cell. Biol.
1
449-459
1981
501800
Vos S.,de Jersey J.,Martin J.L.
Crystal structure of Escherichia coli xanthine phosphoribosyltransferase.
Biochemistry
36
4125-4134
1997
501801
Deo S.S.,Tseng W.C.,Saini R.,Coles R.S.,Athwal R.S.
Purification and characterization of Escherichia coli xanthine-guanine phosphoribosyltransferase produced by plasmid pSV2gpt.
Biochim. Biophys. Acta
839
233-239
1985
501802
Vos S.,de Jersey J.,Martin J.L.
Crystallization and preliminary X-ray crystallographic studies of Escherichia coli xanthine phosphoribosyltransferase.
J. Struct. Biol.
116
330-334
1996
501803
Vos S.,Parry R.J.,Burns M.R.,de Jersey J.,Martin J.L.
Structures of free and complexed forms of Escherichia coli xanthine-guanine phosphoribosyltransferase.
J. Mol. Biol.
282
875-889
1998
501804
Keough D.T.,Hockova D.,Rejman D.,Spacek P.,Vrbkova S.,Krecmerova M.,Eng W.S.,Jans H.,West N.P.,Naesens L.M.,de Jersey J.,Guddat L.W.
Inhibition of the Escherichia coli 6-oxopurine phosphoribosyltransferases by nucleoside phosphonates: potential for new antibacterial agents.
J. Med. Chem.
56
6967-6984
2013