Sequence of TRIM5_CHLAE
EC Number:2.3.2.27
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N6-ubiquitinyl-L-lysine
Other sequences found for EC No. 2.3.2.27
General information:
Sequence
0 MASGILLNVK EEVTCPICLE LLTEPLSLPC GHSFCQACIT ANHKESMLYK EEERSCPVCR
60 ISYQPENIQP NRHVANIVEK LREVKLSPEE GQKVDHCARH GEKLLLFCQE DSKVICWLCE
120 RSQEHRGHHT FLMEEVAQEY HVKLQTALEM LRQKQQEAEK LEADIREEKA SWKIQIDYDK
180 TNVSADFEQL REILDWEESN ELQNLEKEEE DILKSLTKSE TEMVQQTQYM RELISDLEHR
240 LQGSMMELLQ GVDGIIKRVE NMTLKKPKTF HKNQRRVFRA PDLKGMLDMF RELTDVRRYW
300 VDVTLAPNNI SHAVIAEDKR QVSYQNPQIM YQAPGSSFGS LTNFNYCTGV LGSQSITSRK
360 LTNFNYCTGV LGSQSITSGK HYWEVDVSKK SAWILGVCAG FQPDATYNIE QNENYQPKYG
420 YWVIGLQEGD KYSVFQDSSS HTPFAPFIVP LSVIICPDRV GVFVDYEACT VSFFNITNHG
480 FLIYKFSQCS FSKPVFPYLN PRKCTVPMTL CSPSS
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
494936
Hatziioannou T.,Perez-Caballero D.,Yang A.,Cowan S.,Bieniasz P.D.
Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alpha.
Proc. Natl. Acad. Sci. U.S.A.
101
10774-10779
2004
494937
Yap M.W.,Nisole S.,Lynch C.,Stoye J.P.
Trim5alpha protein restricts both HIV-1 and murine leukemia virus.
Proc. Natl. Acad. Sci. U.S.A.
101
10786-10791
2004
494938
Nakayama E.E.,Miyoshi H.,Nagai Y.,Shioda T.
A specific region of 37 amino acid residues in the SPRY (B30.2) domain of African green monkey TRIM5alpha determines species-specific restriction of simian immunodeficiency virus SIVmac infection.
J. Virol.
79
8870-8877
2005
494939
Sawyer S.L.,Wu L.I.,Emerman M.,Malik H.S.
Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain.
Proc. Natl. Acad. Sci. U.S.A.
102
2832-2837
2005