Sequence of KAT2A_MOUSE

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
histone acetyltransferase
Q9JHD2
Mus musculus
830
93394
Reaction
acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N6-acetyl-L-lysine
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MAEPSQAPNP VPAAQPRPLH SPAPAPTSTP APSPASASTP APTPAPAPAP AAAPAGSTGS
 60 GGAGVGSGGD PARPGLSQQQ RASQRKAQVR GLPRAKKLEK LGVFSACKAN ETCKCNGWKN
120 PKPPTAPRMD LQQPAANLSE LCRSCEHPLA DHVSHLENVS EDEINRLLGM VVDVENLFMS
180 VHKEEDTDTK QVYFYLFKLL RKCILQMTRP VVEGSLGSPP FEKPNIEQGV LNFVQYKFSH
240 LAPRERQTMF ELSKMFLLCL NYWKLETPAQ FRQRSQSEDV ATYKVNYTRW LCYCHVPQSC
300 DSLPRYETTH VFGRSLLRSI FTVTRRQLLE KFRVEKDKLV PEKRTLILTH FPKFLSMLEE
360 EIYGANSPIW ESGFTMPPSE GTQLVPRPAT VSATVVPSFS PSMGGGSNSS LSLDSAGTEP
420 MPAGEKRKLP ENLTLEDAKR LRVMGDIPME LVNEVMLTIT DPAAMLGPET SLLSANAARD
480 ETARLEERRG IIEFHVIGNS LTPKANRRVL LWLVGLQNVF SHQLPRMPKE YIARLVFDPK
540 HKTLALIKDG RVIGGICFRM FPTQGFTEIV FCAVTSNEQV KGYGTHLMNH LKEYHIKHSI
600 LYFLTYADEY AIGYFKKQGF SKDIKVPKSR YLGYIKDYEG ATLMECELNP RIPYTELSHI
660 IKKQKEIIKK LIERKQAQIR KVYPGLSCFK EGVRQIPVES VPGIRETGWK PLGKEKGKEL
720 KDPDQLYTTL KNLLAQIKSH PSAWPFMEPV KKSEAPDYYE VIRFPIDLKT MTERLRSRYY
780 VTRKLFVADL QRVIANCREY NPPDSEYCRC ASALEKFFYF KLKEGGLIDK
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
46345
Xu W.,Edmondson D.G.,Roth S.Y.
Mammalian GCN5 and P/CAF acetyltransferases have homologous amino-terminal domains important for recognition of nucleosomal substrates.
Mol. Cell. Biol.
18
5659-5669
1998
46346
Carninci P.,Kasukawa T.,Katayama S.,Gough J.,Frith M.C.,Maeda N.,Oyama R.,Ravasi T.,Lenhard B.,Wells C.,Kodzius R.,Shimokawa K.,Bajic V.B.,Brenner S.E.,Batalov S.,Forrest A.R.,Zavolan M.,Davis M.J.,Wilming L.G.,Aidinis V.,Allen J.E.,Ambesi-Impiombato A.,Apweiler R.,Aturaliya R.N.,Bailey T.L.,Bansal M.,Baxter L.,Beisel K.W.,Bersano T.,Bono H.,Chalk A.M.,Chiu K.P.,Choudhary V.,Christoffels A.,Clutterbuck D.R.,Crowe M.L.,Dalla E.,Dalrymple B.P.,de Bono B.,Della Gatta G.,di Bernardo D.,Down T.,Engstrom P.,Fagiolini M.,Faulkner G.,Fletcher C.F.,Fukushima T.,Furuno M.,Futaki S.,Gariboldi M.,Georgii-Hemming P.,Gingeras T.R.,Gojobori T.,Green R.E.,Gustincich S.,Harbers M.,Hayashi Y.,Hensch T.K.,Hirokawa N.,Hill D.,Huminiecki L.,Iacono M.,Ikeo K.,Iwama A.,Ishikawa T.,Jakt M.,Kanapin A.,Katoh M.,Kawasawa Y.,Kelso J.,Kitamura H.,Kitano H.,Kollias G.,Krishnan S.P.,Kruger A.,Kummerfeld S.K.,Kurochkin I.V.,Lareau L.F.,Lazarevic D.,Lipovich L.,Liu J.,Liuni S.,McWilliam S.,Madan Babu M.,Madera M.,Marchionni L.,Matsuda H.,Matsuzawa S.,Miki H.,Mignone F.,Miyake S.,Morris K.,Mottagui-Tabar S.,Mulder N.,Nakano N.,Nakauchi H.,Ng P.,Nilsson R.,Nishiguchi S.,Nishikawa S.,Nori F.,Ohara O.,Okazaki Y.,Orlando V.,Pang K.C.,Pavan W.J.,Pavesi G.,Pesole G.,Petrovsky N.,Piazza S.,Reed J.,Reid J.F.,Ring B.Z.,Ringwald M.,Rost B.,Ruan Y.,Salzberg S.L.,Sandelin A.,Schneider C.,Schoenbach C.,Sekiguchi K.,Semple C.A.,Seno S.,Sessa L.,Sheng Y.,Shibata Y.,Shimada H.,Shimada K.,Silva D.,Sinclair B.,Sperling S.,Stupka E.,Sugiura K.,Sultana R.,Takenaka Y.,Taki K.,Tammoja K.,Tan S.L.,Tang S.,Taylor M.S.,Tegner J.,Teichmann S.A.,Ueda H.R.,van Nimwegen E.,Verardo R.,Wei C.L.,Yagi K.,Yamanishi H.,Zabarovsky E.,Zhu S.,Zimmer A.,Hide W.,Bult C.,Grimmond S.M.,Teasdale R.D.,Liu E.T.,Brusic V.,Quackenbush J.,Wahlestedt C.,Mattick J.S.,Hume D.A.,Kai C.,Sasaki D.,Tomaru Y.,Fukuda S.,Kanamori-Katayama M.,Suzuki M.,Aoki J.,Arakawa T.,Iida J.,Imamura K.,Itoh M.,Kato T.,Kawaji H.,Kawagashira N.,Kawashima T.,Kojima M.,Kondo S.,Konno H.,Nakano K.,Ninomiya N.,Nishio T.,Okada M.,Plessy C.,Shibata K.,Shiraki T.,Suzuki S.,Tagami M.,Waki K.,Watahiki A.,Okamura-Oho Y.,Suzuki H.,Kawai J.,Hayashizaki Y.
The transcriptional landscape of the mammalian genome.
Science
309
1559-1563
2005
46347
Church D.M.,Goodstadt L.,Hillier L.W.,Zody M.C.,Goldstein S.,She X.,Bult C.J.,Agarwala R.,Cherry J.L.,DiCuccio M.,Hlavina W.,Kapustin Y.,Meric P.,Maglott D.,Birtle Z.,Marques A.C.,Graves T.,Zhou S.,Teague B.,Potamousis K.,Churas C.,Place M.,Herschleb J.,Runnheim R.,Forrest D.,Amos-Landgraf J.,Schwartz D.C.,Cheng Z.,Lindblad-Toh K.,Eichler E.E.,Ponting C.P.
Lineage-specific biology revealed by a finished genome assembly of the mouse.
PLoS Biol.
7
0-0
2009
46349
Xu W.,Edmondson D.G.,Evrard Y.A.,Wakamiya M.,Behringer R.R.,Roth S.Y.
Loss of Gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development.
Nat. Genet.
26
229-232
2000
46350
Wiper-Bergeron N.,Salem H.A.,Tomlinson J.J.,Wu D.,Hache R.J.
Glucocorticoid-stimulated preadipocyte differentiation is mediated through acetylation of C/EBPbeta by GCN5.
Proc. Natl. Acad. Sci. U.S.A.
104
2703-2708
2007
46351
Carracedo A.,Weiss D.,Leliaert A.K.,Bhasin M.,de Boer V.C.,Laurent G.,Adams A.C.,Sundvall M.,Song S.J.,Ito K.,Finley L.S.,Egia A.,Libermann T.,Gerhart-Hines Z.,Puigserver P.,Haigis M.C.,Maratos-Flier E.,Richardson A.L.,Schafer Z.T.,Pandolfi P.P.
A metabolic prosurvival role for PML in breast cancer.
J. Clin. Invest.
122
3088-3100
2012
46352
Stilling R.M.,Roenicke R.,Benito E.,Urbanke H.,Capece V.,Burkhardt S.,Bahari-Javan S.,Barth J.,Sananbenesi F.,Schuetz A.L.,Dyczkowski J.,Martinez-Hernandez A.,Kerimoglu C.,Dent S.Y.,Bonn S.,Reymann K.G.,Fischer A.
K-Lysine acetyltransferase 2a regulates a hippocampal gene expression network linked to memory formation.
EMBO J.
33
1912-1927
2014
46353
Gao B.,Kong Q.,Zhang Y.,Yun C.,Dent S.Y.R.,Song J.,Zhang D.D.,Wang Y.,Li X.,Fang D.
The histone acetyltransferase Gcn5 positively regulates T cell activation.
J. Immunol.
198
3927-3938
2017