Sequence of AOXC_MOUSE
EC Number:1.2.3.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
an aldehyde + H2O + O2 = a carboxylate + H2O2
General information:
Sequence
show sequence in normal format
>G3X982|aldehyde oxidase|EC 1.2.3.1|Mus musculus|Swiss-Prot
MSPSKESDELIFFVNGKKVTERNADPEVNLLFYLRKVIRLTGTKYGCGGGDCGACTVMIS
RYDPISKRISHFSATACLVPICSLHGAAVTTVEGIGSTKTRIHPVQERIAKGHGTQCGFC
TPGMVMSIYTLLRNHPEPSTEQIMETLGGNLCRCTGYRPIVESAKSFCPSSTCCQMNGEG
KCCLDEEKNEPERKNSVCTKLYEKKEFQPLDPTQELIFPPELMRMAEESQNTVLTFRGER
TTWIAPGTLNDLLELKMKHPSAPLVIGNTYLGLHMKFTDVSYPIIISPARILELFVVTNT
KQGLTLGAGLSLTQVKNVLSDVVSRLPKEKTQIYCALLKQLKTLAGQQIRNVASLGGHII
SRLPTSDLNPILGIGNCILNVASTEGIQQIPLNDHFLAGVPDAILKPEQVLISVFVPRSS
KWEFVSAFRQAPRQQNAFATVNAGMKVVFKEDTNTITDLGILYGGIGATVISADKSCRQL
IGRCWDEEMLDDAGKMICEEVSLLMAAPGGMEEYRKTLAISFLFMFYLDVLKQLKTRDPH
KYPDISQKLLHILEDFPLTMPYGMQSFQDVDFQQPLQDPIGRPIMHQSGIKHATGEAVFC
DDMSVLPGELFLAVVTSSKSHAKIISLDASEALASLGVVDVVTARDVPGDNGREEESLYA
QDEVICVGQIVCAVAADSYAHAQQAAKKVKIVYQDIEPMIVTVQDALQYESFIGPERKLE
QGNVEEAFQCADQILEGEVHLGGQEHFYMETQSVRVVPKGEDKEMDIYVSSQDAAFTQEM
VARTLGIPKNRINCHVKRVGGAFGGKASKPGLLASVAAVAAQKTGRPIRFILERRDDMLI
TGGRHPLLGKYKIGFMNNGKIKAADIQLYINGGCTPDDSELVIEYALLKLENAYKIPNLR
VRGRVCKTNLPSNTAFRGFGFPQGAFVTETCMSAVAAKCRLPPEKVRELNMYRTIDRTIH
NQEFDPTNLLQCWEACVENSSYYNRKKAVDEFNQQRFWKKRGIAIIPMKFSVGFPKTFYY
QAAALVQIYTDGSVLVAHGGVELGQGINTKMIQVASRELKIPMSYIHLDEMSTVTVPNTV
TTGASTGADVNGRAVQNACQILMKRLEPIIKQNPSGTWEEWVKEAFVQSISLSATGYFRG
YQADMDWEKGEGDIFPYFVFGAACSEVEIDCLTGAHKNIRTDIVMDGSFSINPAVDIGQI
EGAFVQGLGLYTLEELKYSPEGVLYTRGPHQYKIASVTDIPEEFHVSLLTPTPNPKAIYS
SKGLGEAGTFLGCSVFFAIAAAVAAAREERGLSPIWAINSPATAEVIRMACEDQFTNLVP
QTDSKCCKPWSIPVA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
227413
Terao M.,Kurosaki M.,Marini M.,Vanoni M.A.,Saltini G.,Bonetto V.,Bastone A.,Federico C.,Saccone S.,Fanelli R.,Salmona M.,Garattini E.
Purification of the aldehyde oxidase homolog 1 (AOH1) protein and cloning of the AOH1 and aldehyde oxidase homolog 2 (AOH2) genes. Identification of a novel molybdo-flavoprotein gene cluster on mouse chromosome 1.
J. Biol. Chem.
276
46347-46363
2001
227414
Church D.M.,Goodstadt L.,Hillier L.W.,Zody M.C.,Goldstein S.,She X.,Bult C.J.,Agarwala R.,Cherry J.L.,DiCuccio M.,Hlavina W.,Kapustin Y.,Meric P.,Maglott D.,Birtle Z.,Marques A.C.,Graves T.,Zhou S.,Teague B.,Potamousis K.,Churas C.,Place M.,Herschleb J.,Runnheim R.,Forrest D.,Amos-Landgraf J.,Schwartz D.C.,Cheng Z.,Lindblad-Toh K.,Eichler E.E.,Ponting C.P.
Lineage-specific biology revealed by a finished genome assembly of the mouse.
PLoS Biol.
7
E1000112-E1000112
2009
227416
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
227417
Kurosaki M.,Terao M.,Barzago M.M.,Bastone A.,Bernardinello D.,Salmona M.,Garattini E.
The aldehyde oxidase gene cluster in mice and rats. Aldehyde oxidase homologue 3, a novel member of the molybdo-flavoenzyme family with selective expression in the olfactory mucosa.
J. Biol. Chem.
279
50482-50498
2004
227418
Terao M.,Kurosaki M.,Barzago M.M.,Fratelli M.,Bagnati R.,Bastone A.,Giudice C.,Scanziani E.,Mancuso A.,Tiveron C.,Garattini E.
Role of the molybdoflavoenzyme aldehyde oxidase homolog 2 in the biosynthesis of retinoic acid: generation and characterization of a knockout mouse.
Mol. Cell. Biol.
29
357-377
2009
227419
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
227420
Mahro M.,Coelho C.,Trincao J.,Rodrigues D.,Terao M.,Garattini E.,Saggu M.,Lendzian F.,Hildebrandt P.,Romao M.J.,Leimkuhler S.
Characterization and crystallization of mouse aldehyde oxidase 3: from mouse liver to Escherichia coli heterologous protein expression.
Drug Metab. Dispos.
39
1939-1945
2011
227421
Kurosaki M.,Bolis M.,Fratelli M.,Barzago M.M.,Pattini L.,Perretta G.,Terao M.,Garattini E.
Structure and evolution of vertebrate aldehyde oxidases: from gene duplication to gene suppression.
Cell. Mol. Life Sci.
70
1807-1830
2013
227422
Coelho C.,Mahro M.,Trincao J.,Carvalho A.T.,Ramos M.J.,Terao M.,Garattini E.,Leimkuhler S.,Romao M.J.
The first mammalian aldehyde oxidase crystal structure: insights into substrate specificity.
J. Biol. Chem.
287
40690-40702
2012
