Sequence of PNTD_STRAE
EC Number:1.14.11.36
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
pentalenolactone D + 2 2-oxoglutarate + 2 O2 = pentalenolactone F + 2 succinate + 2 CO2 + H2O
General information:
Sequence
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>E3VWI8|pentalenolactone F synthase|EC 1.14.11.36|Streptomyces arenae|Swiss-Prot
MEVTPIPGAPLGAVVHGARVTGDMDKTHLEEIWSALDTYLVLVLRGHETPSYEEFLAFGR
RFGHIPKTGLTSGAHPEHNEILIVSNLVEDGRKIGVGDAEWMGWHTDYSFRPRVSQVGFL
EAVEVPYSGGGETLFTDMYALYESLSPEERRRLHSFRVRHALRTGYEETIEEELQREVTL
GEGADRIQPEDGTSTVHPLIARNPRTGRRSVYISTLNTERIVDLAPDDSRELLDGLLAHA
GKPQYTYAHTWQPGDLVVWDQLGTVHAKQAFDPAERRVMRQVVSIFDDPAGPWRAEAAA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
215608
Zhu D.,Seo M.J.,Ikeda H.,Cane D.E.
Genome mining in streptomyces. Discovery of an unprecedented P450-catalyzed oxidative rearrangement that is the final step in the biosynthesis of pentalenolactone.
J. Am. Chem. Soc.
133
2128-2131
2011
215609
Seo M.J.,Zhu D.,Endo S.,Ikeda H.,Cane D.E.
Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone.
Biochemistry
50
1739-1754
2011
