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Sequence of PNTD_STRAE

EC Number:1.14.11.36

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
pentalenolactone F synthase
E3VWI8
Streptomyces arenae
299
33460
Reaction
pentalenolactone D + 2 2-oxoglutarate + 2 O2 = pentalenolactone F + 2 succinate + 2 CO2 + H2O

General information:

Sequence
show sequence in fasta format
  0 MEVTPIPGAP LGAVVHGARV TGDMDKTHLE EIWSALDTYL VLVLRGHETP SYEEFLAFGR
 60 RFGHIPKTGL TSGAHPEHNE ILIVSNLVED GRKIGVGDAE WMGWHTDYSF RPRVSQVGFL
120 EAVEVPYSGG GETLFTDMYA LYESLSPEER RRLHSFRVRH ALRTGYEETI EEELQREVTL
180 GEGADRIQPE DGTSTVHPLI ARNPRTGRRS VYISTLNTER IVDLAPDDSR ELLDGLLAHA
240 GKPQYTYAHT WQPGDLVVWD QLGTVHAKQA FDPAERRVMR QVVSIFDDPA GPWRAEAAA
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
215608
Zhu D.,Seo M.J.,Ikeda H.,Cane D.E.
Genome mining in streptomyces. Discovery of an unprecedented P450-catalyzed oxidative rearrangement that is the final step in the biosynthesis of pentalenolactone.
J. Am. Chem. Soc.
133
2128-2131
2011
215609
Seo M.J.,Zhu D.,Endo S.,Ikeda H.,Cane D.E.
Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone.
Biochemistry
50
1739-1754
2011