Sequence of I18RA_HUMAN

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase
O95256
Homo sapiens
599
68310
Reaction
cyclic ADP-ribose + H2O = ADP-D-ribose
Sequences with same EC No.
Sequence
show sequence in fasta format
  0 MLCLGWIFLW LVAGERIKGF NISGCSTKKL LWTYSTRSEE EFVLFCDLPE PQKSHFCHRN
 60 RLSPKQVPEH LPFMGSNDLS DVQWYQQPSN GDPLEDIRKS YPHIIQDKCT LHFLTPGVNN
120 SGSYICRPKM IKSPYDVACC VKMILEVKPQ TNASCEYSAS HKQDLLLGST GSISCPSLSC
180 QSDAQSPAVT WYKNGKLLSV ERSNRIVVDE VYDYHQGTYV CDYTQSDTVS SWTVRAVVQV
240 RTIVGDTKLK PDILDPVEDT LEVELGKPLT ISCKARFGFE RVFNPVIKWY IKDSDLEWEV
300 SVPEAKSIKS TLKDEIIERN IILEKVTQRD LRRKFVCFVQ NSIGNTTQSV QLKEKRGVVL
360 LYILLGTIGT LVAVLAASAL LYRHWIEIVL LYRTYQSKDQ TLGDKKDFDA FVSYAKWSSF
420 PSEATSSLSE EHLALSLFPD VLENKYGYSL CLLERDVAPG GVYAEDIVSI IKRSRRGIFI
480 LSPNYVNGPS IFELQAAVNL ALDDQTLKLI LIKFCYFQEP ESLPHLVKKA LRVLPTVTWR
540 GLKSVPPNSR FWAKMRYHMP VKNSQGFTWN QLRITSRIFQ WKGLSRTETT GRSSQPKEW
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
45251
Born T.L.,Thomassen E.,Bird T.A.,Sims J.E.
Cloning of a novel receptor subunit, AcPL, required for interleukin-18 signaling.
J. Biol. Chem.
273
29445-29450
1998
45252
Fiszer D.,Rozwadowska N.,Rychlewski L.,Kosicki W.,Kurpisz M.
Identification of IL-18RAP mRNA truncated splice variants in human testis and the other human tissues.
Cytokine
39
178-183
2007
45253
Hillier L.W.,Graves T.A.,Fulton R.S.,Fulton L.A.,Pepin K.H.,Minx P.,Wagner-McPherson C.,Layman D.,Wylie K.,Sekhon M.,Becker M.C.,Fewell G.A.,Delehaunty K.D.,Miner T.L.,Nash W.E.,Kremitzki C.,Oddy L.,Du H.,Sun H.,Bradshaw-Cordum H.,Ali J.,Carter J.,Cordes M.,Harris A.,Isak A.,van Brunt A.,Nguyen C.,Du F.,Courtney L.,Kalicki J.,Ozersky P.,Abbott S.,Armstrong J.,Belter E.A.,Caruso L.,Cedroni M.,Cotton M.,Davidson T.,Desai A.,Elliott G.,Erb T.,Fronick C.,Gaige T.,Haakenson W.,Haglund K.,Holmes A.,Harkins R.,Kim K.,Kruchowski S.S.,Strong C.M.,Grewal N.,Goyea E.,Hou S.,Levy A.,Martinka S.,Mead K.,McLellan M.D.,Meyer R.,Randall-Maher J.,Tomlinson C.,Dauphin-Kohlberg S.,Kozlowicz-Reilly A.,Shah N.,Swearengen-Shahid S.,Snider J.,Strong J.T.,Thompson J.,Yoakum M.,Leonard S.,Pearman C.,Trani L.,Radionenko M.,Waligorski J.E.,Wang C.,Rock S.M.,Tin-Wollam A.-M.,Maupin R.,Latreille P.,Wendl M.C.,Yang S.-P.,Pohl C.,Wallis J.W.,Spieth J.,Bieri T.A.,Berkowicz N.,Nelson J.O.,Osborne J.,Ding L.,Meyer R.,Sabo A.,Shotland Y.,Sinha P.,Wohldmann P.E.,Cook L.L.,Hickenbotham M.T.,Eldred J.,Williams D.,Jones T.A.,She X.,Ciccarelli F.D.,Izaurralde E.,Taylor J.,Schmutz J.,Myers R.M.,Cox D.R.,Huang X.,McPherson J.D.,Mardis E.R.,Clifton S.W.,Warren W.C.,Chinwalla A.T.,Eddy S.R.,Marra M.A.,Ovcharenko I.,Furey T.S.,Miller W.,Eichler E.E.,Bork P.,Suyama M.,Torrents D.,Waterston R.H.,Wilson R.K.
Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
Nature
434
724-731
2005
45256
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
45257
Tominaga K.,Yoshimoto T.,Torigoe K.,Kurimoto M.,Matsui K.,Hada T.,Okamura H.,Nakanishi K.
IL-12 synergizes with IL-18 or IL-1beta for IFN-gamma production from human T cells.
Int. Immunol.
12
151-160
2000
45258
Sareneva T.,Julkunen I.,Matikainen S.
IFN-alpha and IL-12 induce IL-18 receptor gene expression in human NK and T cells.
J. Immunol.
165
1933-1938
2000
45259
Debets R.,Timans J.C.,Churakowa T.,Zurawski S.,de Waal Malefyt R.,Moore K.W.,Abrams J.S.,O'Garra A.,Bazan J.F.,Kastelein R.A.
IL-18 receptors, their role in ligand binding and function: anti-IL-1RAcPL antibody, a potent antagonist of IL-18.
J. Immunol.
165
4950-4956
2000
45260
Kato Z.,Jee J.,Shikano H.,Mishima M.,Ohki I.,Ohnishi H.,Li A.,Hashimoto K.,Matsukuma E.,Omoya K.,Yamamoto Y.,Yoneda T.,Hara T.,Kondo N.,Shirakawa M.
The structure and binding mode of interleukin-18.
Nat. Struct. Biol.
10
966-971
2003
45261
Tsutsumi N.,Kimura T.,Arita K.,Ariyoshi M.,Ohnishi H.,Yamamoto T.,Zuo X.,Maenaka K.,Park E.Y.,Kondo N.,Shirakawa M.,Tochio H.,Kato Z.
The structural basis for receptor recognition of human interleukin-18.
Nat. Commun.
5
5340-5340
2014