Sequence of POLG_HCVJ1
EC Number:3.4.21.98
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Hydrolysis of four peptide bonds in the viral precursor polyprotein, commonly with Asp or Glu in the P6 position, Cys or Thr in P1 and Ser or Ala in P1'
Other sequences found for EC No. 3.4.21.98
General information:
Sequence
0 MSTIPKPQRK TKRNTNRRPQ DVKFPGGGQI VGGVYLLPRR GPRLGVRATR KTSERSQPRG
60 RRQPIPKVRR PEGRTWAQPG YPWPLYGNEG CGWAGWLLSP RGSRPSWGPT DPRRRSRNLG
120 KVIDTLTCGF ADLMGYIPLV GAPLGGAARA LAHGVRVLED GVNYATGNLP GCSFSIFLLA
180 LLSCLTVPAS AYQVRNSTGL YHVTNDCPNS SIVYEAHDAI LHTPGCVPCV REGNVSRCWV
240 AMTPTVATRD GKLPATQLRR HIDLLVGSAT LCSALYVGDL CGSVFLIGQL FTFSPRRHWT
300 TQGCNCSIYP GHITGHRMAW DMMMNWSPTA ALVMAQLLRI PQAILDMIAG AHWGVLAGIA
360 YFSMVGNWAK VLVVLLLFAG VDAETIVSGG QAARAMSGLV SLFTPGAKQN IQLINTNGSW
420 HINSTALNCN ESLNTGWLAG LIYQHKFNSS GCPERLASCR RLTDFDQGWG PISHANGSGP
480 DQRPYCWHYP PKPCGIVPAK SVCGPVYCFT PSPVVVGTTD RSGAPTYNWG ANDTDVFVLN
540 NTRPPLGNWF GCTWMNSTGF TKVCGAPPCV IGGGGNNTLH CPTDCFRKHP EATYSRCGSG
600 PWITPRCLVD YPYRLWHYPC TINYTIFKVR MYVGGVEHRL DAACNWTRGE RCDLEDRDRS
660 ELSPLLLSTT QWQVLPCSFT TLPALSTGLI HLHQNIVDVQ YLYGVGSSIA SWAIKWEYVV
720 LLFLLLADAR VCSCLWMMLL ISQAEAALEN LVILNAASLA GTRGLVSFLV FFCFAWYLKG
780 RWVPGAAYAL YGMWPLLLLL LALPQRAYAL DTEVAASCGG VVLVGLMALT LSPYYKRCIS
840 WCLWWLQYFL TRVEAQLHVW VPPLNVRGGR DAVILLMCVV HPTLVFDITK LLLAVLGPLW
900 ILQASLLKVP YFVRVQGLLR ICALARKMVG GHYVQMAIIK LGALTGTYVY NHLTPLRDWA
960 HNGLRDLAVA VEPVVFSQME TKLITWGADT AACGDIINGL PVSARKGREI LLGPADGMVS
1020 KGWRLLAPIT AYAQQTRGLL GCIITSLTGR DKNQVEGEVQ IVSTAAQTFL ATCINGVCWT
1080 VYHGAGTRTI ASPKGPVIQM YTNVDQDLVG WPAPQGARSL TPCTCGSSDL YLVTRHADVI
1140 PVRRRGDSRG SLLSPRPISY LKGSSGGPLL CPAGHVVGIF RAAVCTRGVA KAVDFIPVES
1200 LETTMRSPVF TDNSSPPAVP QSFQVAHLHA PTGSGKSTKV PAAYAAQGYK VLVLNPSVAA
1260 TLGFGAYMSK AHGIDPNIRT GVRTITTGSP ITYSTYGKFL ADGGCSGGAY DIIICDECHS
1320 TDATSVLGIG TVLDQAETAG ARLVVLATAT PPGSITVPHA NIEEVALSTT GEIPFYGKAI
1380 PLEAIKGGRH LIFCHSKKKC DELAAKLVAL GVNAVAYYRG LDVSVIPTSG DVVVVATDAL
1440 MTGYTGDFDS VIDCNTCVTQ TVDFSLDPTF TIETTTLPQD AVSRTQRRGR TGRGKPGIYR
1500 FVAPGERPSG MFDSSILCEC YDTGCAWYEL TPAETTVRLR AYMNTPGLPV CQDHLEFWEG
1560 VFTGLTHIDA HFLSQTKQGG ENFPYLVAYQ ATVCARAQAP PPSWDQMWKC LIRLKPTLHG
1620 PTPLLYRLGA VQGEVTLTHP VTKYIMTCMS ADLEVVTSTW VLVGGVLAAL AAYCLSTGCV
1680 VIVGRIVLSG RPAIIPDREV LYREFDEMEE CSQHLPYIEQ GMMLAEQFKQ KALGLLQTAS
1740 RQAEVIAPTV QTNWQKLEAF WAKHMWNFIS GIQYLAGLST LPGNPAIASL MAFTAAVTSP
1800 LTTSQTLLFN ILGGWVAAQL AAPGAATAFV GSGLAGAAVG SVGLGRVLVD ILAGYGAGVA
1860 GALVAFKIMS GELPSTEDLV NLLPAILSPG ALVVGVVCAA ILRRHVGPGE GAVQWMNRLI
1920 AFASRGNHVS PTHYVPESDA AARVTAILSS LTVTQLLRRL HQWLSSESTT PCSGSWLRDI
1980 WDWICEVLSD FKTWLKTKLM PHLPGIPFVS CQHGYKGVWR GDGIMHTRCH CGAEITGHVK
2040 NGTMRIVGPK TCRNMWSGTF PINAYTTGPC TPLPAPNYTF ALWRVSAEEY VEIRRVGDFH
2100 YVTGMTTDNL KCPCQVPSPE FFTELDGVRL HRFAPPCKPL LREEVSFRVG LHDYPVGSQL
2160 PCEPEPDVAV LTSMLTDPSH ITAAAAGRRL ARGSPPSEAS SSASQLSAPS LKATCTINHD
2220 SPDAELIEAN LLWRQEMGGN ITRVESENKV VILDSFDPLV AEEDEREISV PAEILRKSRR
2280 FTQALPIWAR PDYNPPLIET WKKPNYEPPV VHGCPLPPPQ SPPVPPPRKK RTVVLTESTL
2340 STALAELAAK SFGSSSTSGI TGDNTTTSSE PAPSGCSPDS DAESYSSMPP LEGEPGDPDL
2400 SDGSWSTVSS EAGTEDVVCC SMSYTWTGAL ITPCAAEEQK LPINALSNSL LRHHNLVYST
2460 TSRSACQRQK KVTFDRLQVL DSHYQDVLKE VKAAASKVKA NLLSVEEACS LTPPHSAKSK
2520 FGYGAKDVRC HARKAVNHIN SVWKDLLEDS VTPIQTTIMA KNEVFCVQPE KGGRKPARLI
2580 VFPDLGVRVC EKMALYDVVS KLPPAVMGSS YGFQYSPGQR VEFLVQAWKS KRTPMGFSYD
2640 TRCFDSTVTE SDIRTEEAIY QCCDLDPQAR VAIRSLTERL YVGGPLTNSR GENCGYRRCR
2700 ASGVLTTSCG NTLTCYIKAR AACRAAGLQD CTMLVCGDDL VVICESAGVQ EDAASLRAFT
2760 EAMTRYSAPP GDPPQPEYDL ELITSCSSNV SVAHDGTGKR VYYLTRDPTT PLARAAWETA
2820 RHTPVNSWLG NIIMFAPTLW ARMILMTHFF SVLIARDQLE QALDCEIYGA CYSIEPLDLP
2880 PIIQRLHGLS AFSLHSYSPG EINRVAACLR KLGVPPLRAW RHRARSVRAR LLSRGGRAAI
2940 CGKYLFNWAV RTKLKLTPIA AAGRLDLSGW FTAGYSGGDI YHSVSHARPR WFWFCLLLLA
3000 AGVGIYLLPN R
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
460624
Okamoto H.,Kanai N.,Mishiro S.
Full-length nucleotide sequence of a Japanese hepatitis C virus isolate (HC-J1) with high homology to USA isolates.
Nucleic Acids Res.
20
6410-6410
1992
460625
Shirakura M.,Murakami K.,Ichimura T.,Suzuki R.,Shimoji T.,Fukuda K.,Abe K.,Sato S.,Fukasawa M.,Yamakawa Y.,Nishijima M.,Moriishi K.,Matsuura Y.,Wakita T.,Suzuki T.,Howley P.M.,Miyamura T.,Shoji I.
E6AP ubiquitin ligase mediates ubiquitylation and degradation of hepatitis C virus core protein.
J. Virol.
81
1174-1185
2007
