Sequence of PEPA2_MACFU
EC Number:3.4.23.1
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
Preferential cleavage: hydrophobic, preferably aromatic, residues in P1 and P1' positions. Cleaves Phe1-/-Val, Gln4-/-His, Glu13-/-Ala, Ala14-/-Leu, Leu15-/-Tyr, Tyr16-/-Leu, Gly23-/-Phe, Phe24-/-Phe and Phe25-/-Tyr bonds in the B chain of insulin
Other sequences found for EC No. 3.4.23.1
General information:
Sequence
0 MKWLLLLGLV ALSECIIHKV PLVRKKSLRR NLSEHGLLKD FLKKHNFNPA SKYFPQAEAP
60 TLIDEQPLEN YLDMEYFGTI GIGTPAQDFT VIFDTGSSNL WVPSVYCSSL ACTNHNRFNP
120 QDSSTYQSTS GTVSITYGTG SMTGILGYDT VQVGGISDTN QIFGLSETEP GSFLYYAPFD
180 GILGLAYPSI SSSGATPVFD NIWNQGLVSQ DLFSVYLSAD DQSGSVVIFG GIDSSYYTGS
240 LNWVPVSVEG YWQISVDSIT MNGEAIACAE GCQAIVDTGT SLLTGPTSPI ANIQSDIGAS
300 ENSDGEMVVS CSAISSLPDI VFTINGIQYP VPPSAYILQS QGSCISGFQG MDVPTESGEL
360 WILGDVFIRQ YFTVFDRANN QVGLAPVA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
457431
Kageyama T.,Tanabe K.,Koiwai O.
Development-dependent expression of isozymogens of monkey pepsinogens and structural differences between them.
Eur. J. Biochem.
202
205-215
1991
