Sequence of PATK_PENEN
EC Number:2.3.1.165
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
acetyl-CoA + 3 malonyl-CoA + NADPH + H+ = 6-methylsalicylate + 4 CoA + 3 CO2 + NADP+ + H2O
Other sequences found for EC No. 2.3.1.165
General information:
Sequence
0 MHSVSPSTYP SGGTSPAPAD TPGTEYSEYE FSNDVAVVGM ACRVAGGNHN PELLWQSLLS
60 QKSAVGEIPE MRWEPYYRRD PRNAKELKKT TSRGYFLDRL EDFDCQFFGI SPKEAEQMDP
120 QQRVSLEVAS EALEDAGIPA KSLSGSDTAV FWGVNSDDYS KLVLEDLPNV EAWMGIGTAY
180 CGVPNRISYH LNLMGPSTAV DAACASSLVA VHHGVQAIRL GESQVAIVGG VNALCGPGLT
240 RVLDKAGAIS SDGSCKSFDD DAHGYARGEG AGALVLKSLH RALLDHDNVL AVIKGSAVAQ
300 DGKTNGIMAP NAKAQQLAAR TALNVAGVDP STVRYVEAHA TSTPLGDPTE ISAIAGVYGT
360 NRPADDPCYI GSIKPNIGHL EAGAGVMGFI KAILTIQKGV LPPQANLTNL NSRIDWKTAG
420 VKVVQEATPW PSSDPIRRAG VCSYGYGGTV SHAVIEEFNP ILRPDPLDDG AATGPGLLLL
480 SGPQEKRLAL QAKTLREWMT ADGKDNNLSE ILTTLATRRD HHDYRAALVV DDHLDATQVL
540 QALANGTDHS FTTQSRVLGA DVSKDVVWVF SGHGAQWPDM GKQLIHNPVF FAAIQPLDEL
600 IQAEIGLSPI ELLRTGDFES SDRVQILTYL MQIGLSAILQ SNGITPQAVI GHSVGEIAAS
660 VVAGALTSAE GALIVTRRAL LYRQVMGKGG MILVNLPSAE TEEILGRRQD LVVAIDSSPS
720 SCVVAGDKDI VAETAEAFKA RGVKTFTVKS DIAFHSPTLN VLMDPLRDAL GQALAPTVHI
780 KLYSTALVDP RGQDVRDLEY WTGNMVNRVR LTSAIQAAVE DGYRLFLEVS THPVVSHSIN
840 ETLMDAGLED FAVIPTLLRK KPTEKHILHS IAQLHCRGAE VNWAAQMPGR WATGLPTTTW
900 MHKPIWRKIE TAPLHTGLTH DVEKHTLLGQ RIPVPGTDTF VYTSRLDNET KPFPGSHPLH
960 GTEIVPAAGL INTFLKGTGG QMLQNVVLRV PVAINAPRSV QVVVQQDQVK VVSRLISSDP
1020 SLSDDDASWV THTTAYWDRK VLGSADRIDL AAVKARLTTK LADNFSIDYL DKVGVSAMGF
1080 PWAVTEHYRD TKQMLARVDV NPAVLGDDPL PWDSSSWAPV LDAATSVGST VFQTAALRMP
1140 AQIERVEIFT SEDPPKISYL FVEEASDSVP TSHVSVLSET GEVLAKFTAM RFSEIEGTPG
1200 VSGSMESLVH QIAWPPATPA EEPLLITKVI LVSPDATARA QYAATLPTQV QSFQFSTTED
1260 FFSNASSLPL EKGTVVAYIP GEVASLAEVP AASESFTWNL LELIKFIVNG SLPIKVFTLT
1320 SSVGDGQTPT ALAQSPLIGL ARIIASEHPD LGSLIDIEEP KIPLSTMRYI QGADVIRISD
1380 GIARVSRFRS LPRTKLRPAS EGPRLLPRPD GTYLITGGLG ILGLEVADFL VEKGARRLLL
1440 ISRRALPPRR TWDQVSEDLQ PTIAKIRLLE SRGASVHVLP LDITKPDAVE QLSTALDRLS
1500 LPAVQGVVHA AGVLDNEMVL QTTRDAFNRV LAPKIAGALA LHEVFPPKSV DFFVMFSSCG
1560 NLVGFTGQAS YGSGNAFLDT LATHRARLGD SGAVAFQWTA WRGLGMGSST DFINAELEAK
1620 GITDVTRDEA FAAWQHLAKY DIDHGVVLRS LAIDDGEPVP VPILNDIVVR RVSELSGSAQ
1680 AAAGSSGNDA VPSSGPELKA YLDEKIRGCV AKVLQMTAED VDSKAALADL GVDSVMTVTL
1740 RRQLQQTLKI PVPPTLTWSH PTVSHLVVWF AEKIGK
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
456000
Tannous J.,El Khoury R.,Snini S.P.,Lippi Y.,El Khoury A.,Atoui A.,Lteif R.,Oswald I.P.,Puel O.
Sequencing, physical organization and kinetic expression of the patulin biosynthetic gene cluster from Penicillium expansum.
Int. J. Food Microbiol.
189C
51-60
2014
456001
Ballester A.R.,Marcet-Houben M.,Levin E.,Sela N.,Selma-Lazaro C.,Carmona L.,Wisniewski M.,Droby S.,Gonzalez-Candelas L.,Gabaldon T.
Genome, transcriptome, and functional analyses of Penicillium expansum provide new insights into secondary metabolism and pathogenicity.
Mol. Plant Microbe Interact.
28
232-248
2015
456003
de Melo F.T.,de Oliveira I.M.,Greggio S.,Dacosta J.C.,Guecheva T.N.,Saffi J.,Henriques J.A.,Rosa R.M.
DNA damage in organs of mice treated acutely with patulin, a known mycotoxin.
Food Chem. Toxicol.
50
3548-3555
2012
456004
Boussabbeh M.,Ben Salem I.,Rjiba-Touati K.,Bouyahya C.,Neffati F.,Najjar M.F.,Bacha H.,Abid-Essefi S.
The potential effect of patulin on mice bearing melanoma cells: an anti-tumour or carcinogenic effect?
Tumor Biol.
37
6285-6295
2016
456005
Kumar D.,Barad S.,Chen Y.,Luo X.,Tannous J.,Dubey A.,Glam Matana N.,Tian S.,Li B.,Keller N.,Prusky D.
LaeA regulation of secondary metabolism modulates virulence in Penicillium expansum and is mediated by sucrose.
Mol. Plant Pathol.
18
1150-1163
2017
456006
Kumar D.,Tannous J.,Sionov E.,Keller N.,Prusky D.
Apple intrinsic factors modulating the global regulator, LaeA, the patulin gene cluster and patulin accumulation during fruit colonization by Penicillium expansum.
Front. Plant Sci.
9
1094-1094
2018
456007
Li B.,Zong Y.,Du Z.,Chen Y.,Zhang Z.,Qin G.,Zhao W.,Tian S.
Genomic characterization reveals insights into patulin biosynthesis and pathogenicity in Penicillium species.
Mol. Plant Microbe Interact.
28
635-647
2015
456008
Li B.,Chen Y.,Zong Y.,Shang Y.,Zhang Z.,Xu X.,Wang X.,Long M.,Tian S.
Dissection of patulin biosynthesis, spatial control and regulation mechanism in Penicillium expansum.
Environ. Microbiol.
21
1124-1139
2019
456009
Clemmensen S.E.,Kromphardt K.J.K.,Frandsen R.J.N.
Marker-free CRISPR-Cas9 based genetic engineering of the phytopathogenic fungus, Penicillium expansum.
Fungal Genet. Biol.
160
103689-103689
2022
