Sequence of CBPC5_AILME
EC Number:3.4.17.24
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
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This is a subfamily of enzymes that cleave C-terminal and/or side chain amino acids from tubulins. The dual-specificity enzymes can cleave both alpha- and gamma-linked L-glutamate from tubulins, removing the posttranslationally added polyglutamyl side chains from the C-terminal regions. In addition, the enzyme removes two glutamate residues from the C-terminus of beta-tubulin and detyrosinated alpha-tubulin (from which the C-terminal L-tyrosine has been removed by EC 3.4.17.17, tubulinyl-Tyr carboxypeptidase). The latter is cleaved to delta2-tubulin and further to delta3-tubulin.
General information:
Sequence
0 MELRCGGLLF SSRFDSGNLA HVEKVDSVSG DGEGGAAGAS APFSSIASSP DYEFNVWTRP
60 DCAETEFENG NRSWFYFSVR GGTPGKLIKI NIMNMNKQSK LYSQGMAPFV RTLPTRPRWE
120 RIRDRPTFEM TETQFVLSFV HRFVEGRGAT TFFAFCYPFS YSDCQDLLNQ LDQRFLENHP
180 THSSPLDTIY YHREILCYSL DGLRVDLLTI TSCHGLREDR EPRLQQLFPD TGTPRPFCFT
240 GKRIFFLSSR VHPGETPSSF VFNGFLDFIL RPDDPRAQTL RRLFVFKLIP MLNPDGVVRG
300 HYRTDSRGVN LNRQYLKPDA ALHPAIYGAK AVLLYHHVHS RLHPQSPSEH QHSPCLPPDA
360 PLSDLEKANH LRNEAHLGHT SDGDSPEDWT QTRPAEQKAS GVWLMPQQCA DAEQPAPDTI
420 PPKESGVAYY VDLHGHASKR GCFMYGNSFS DESTQVENML YPKLISLNSA HFDFQGCNFS
480 EKNMYARDRR DGQSKEGSGR VAIYKASGII HSYTLECNYN TGRSVNSIPA ACHDNGRASP
540 PPPPAFPSRY TVELFEQVGR AMAIAALDMA ECNPWPRIVL SEHSSLTNLR AWMLKHVRSS
600 RGLSSTVSGA VNKKRGSRTP PRSNSGLPVS CSENPLSRAR SFSTGTSAGG SSSSQQNSPQ
660 MKNSPSFPFH GSRPTGLPGL GSSTQKVSHR VLGPVREPRS QDRRRRQQPL THRPTSSSLA
720 PSPNPTSSSP ASSHSTGPCL LPSAFSVSGS SCSLLSSGDK PEAVMVIGKG LLGPRIPCIR
780 TRLQVRPRLG QGSPPTCRGM SGSSGPTSPI PRTRESSEPE PGPHSAPGLP QAGPPRPRSA
840 PAFSPISCSL SDSQSRICYS GGPLGQPEVC FGPKSPPLTV SPRV
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
209764
Li R.,Fan W.,Tian G.,Zhu H.,He L.,Cai J.,Huang Q.,Cai Q.,Li B.,Bai Y.,Zhang Z.,Zhang Y.,Wang W.,Li J.,Wei F.,Li H.,Jian M.,Li J.,Zhang Z.,Nielsen R.,Li D.,Gu W.,Yang Z.,Xuan Z.,Ryder O.A.,Leung F.C.,Zhou Y.,Cao J.,Sun X.,Fu Y.,Fang X.,Guo X.,Wang B.,Hou R.,Shen F.,Mu B.,Ni P.,Lin R.,Qian W.,Wang G.,Yu C.,Nie W.,Wang J.,Wu Z.,Liang H.,Min J.,Wu Q.,Cheng S.,Ruan J.,Wang M.,Shi Z.,Wen M.,Liu B.,Ren X.,Zheng H.,Dong D.,Cook K.,Shan G.,Zhang H.,Kosiol C.,Xie X.,Lu Z.,Zheng H.,Li Y.,Steiner C.C.,Lam T.T.,Lin S.,Zhang Q.,Li G.,Tian J.,Gong T.,Liu H.,Zhang D.,Fang L.,Ye C.,Zhang J.,Hu W.,Xu A.,Ren Y.,Zhang G.,Bruford M.W.,Li Q.,Ma L.,Guo Y.,An N.,Hu Y.,Zheng Y.,Shi Y.,Li Z.,Liu Q.,Chen Y.,Zhao J.,Qu N.,Zhao S.,Tian F.,Wang X.,Wang H.,Xu L.,Liu X.,Vinar T.,Wang Y.,Lam T.W.,Yiu S.M.,Liu S.,Zhang H.,Li D.,Huang Y.,Wang X.,Yang G.,Jiang Z.,Wang J.,Qin N.,Li L.,Li J.,Bolund L.,Kristiansen K.,Wong G.K.,Olson M.,Zhang X.,Li S.,Yang H.,Wang J.,Wang J.
The sequence and de novo assembly of the giant panda genome.
Nature
463
311-317
2010
