Sequence of DCSG_STRLA
EC Number:6.3.3.5
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
O-ureido-D-serine + ATP + H2O = D-cycloserine + CO2 + NH3 + ADP + phosphate
General information:
Sequence
0 MGILALVTDA VSLPIDYDMP PLLEACRTVG ITAEVCDWED GTVDWSRFEA VVFRSPWTWA
60 ERQAEFLAFC ERVSHVTRLI TPMPLVRWAL DKRYLADLAA HGVPVIPTTV VAPGSDALAA
120 VRDFLAARPE AREFVVKPTD GCYSKDVQRY QRSLAEPASR HVARLLANGS HVILQPYVES
180 VDRHGETDLT FFDGVYSHAI HKGAMLMPDG TVHVPTLDFR QARDADEDQR AVAAAALAAS
240 VAHLGLDLPL VCGRVDLVRG ADGSPMVLEM ELCEPSLNLT FSEDGALRFA QALAERLKP
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
210459
Kumagai T.,Koyama Y.,Oda K.,Noda M.,Matoba Y.,Sugiyama M.
Molecular cloning and heterologous expression of a biosynthetic gene cluster for the antitubercular agent D-cycloserine produced by Streptomyces lavendulae.
Antimicrob. Agents Chemother.
54
1132-1139
2010
210460
Uda N.,Matoba Y.,Kumagai T.,Oda K.,Noda M.,Sugiyama M.
Establishment of an in vitro D-cycloserine-synthesizing system by using O-ureido-L-serine synthase and D-cycloserine synthetase found in the biosynthetic pathway.
Antimicrob. Agents Chemother.
57
2603-2612
2013
210461
Uda N.,Matoba Y.,Kumagai T.,Oda K.,Noda M.,Sugiyama M.
Antimicrob. Agents Chemother.
59
7926-7926
2015
210462
Matoba Y.,Uda N.,Kudo M.,Sugiyama M.
Cyclization mechanism catalyzed by an ATP-grasp enzyme essential for D-cycloserine biosynthesis.
FEBS J.
287
2763-2778
2020
