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Sequence of MK10_MOUSE

EC Number:2.7.11.24

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
mitogen-activated protein kinase
Q61831
Mus musculus
464
52532
Reaction
ATP + a [protein]-(L-serine/L-threonine) = ADP + a [protein]-(L-serine/L-threonine) phosphate
Other sequences found for EC No. 2.7.11.24

General information:

Sequence
show sequence in fasta format
  0 MSLHFLYYCS EPTLDVKIAF CQGFDKHVDV SSIAKHYNMS KSKVDNQFYS VEVGDSTFTV
 60 LKRYQNLKPI GSGAQGIVCA AYDAVLDRNV AIKKLSRPFQ NQTHAKRAYR ELVLMKCVNH
120 KNIISLLNVF TPQKTLEEFQ DVYLVMELMD ANLCQVIQME LDHERMSYLL YQMLCGIKHL
180 HSAGIIHRDL KPSNIVVKSD CTLKILDFGL ARTAGTSFMM TPYVVTRYYR APEVILGMGY
240 KENVDIWSVG CIMGEMVRHK ILFPGRSYID QWNKVIEQLG TPCPEFMKKL QPTVRNYVEN
300 RPKYAGLTFP KLFPDSLFPA DSEHNKLKAS QARDLLSKML VIDPVKRISV DDALQHPYIN
360 VWYDPAEVEA PPPQIYDKQL DEREHTIEEW KELIYKEVMN SEEKTKNGVV KSQPSPSGAA
420 VNSSESLPPS SAVNDISSMS TDQTLASDTD SSLEASAGPL GCCR
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
443220
Martin J.H.,Mohit A.A.,Miller C.A.
Developmental expression in the mouse nervous system of the p493F12 SAP kinase.
Brain Res. Mol. Brain Res.
35
47-57
1996
443221
Ito M.,Yoshioka K.,Akechi M.,Yamashita S.,Takamatsu N.,Sugiyama K.,Hibi M.,Nakabeppu Y.,Shiba T.,Yamamoto K.
JSAP1, a novel jun N-terminal protein kinase (JNK)-binding protein that functions as a scaffold factor in the JNK signaling pathway.
Mol. Cell. Biol.
19
7539-7548
1999
443223
Yang D.D.,Kuan C.-Y.,Whitmarsh A.J.,Rincon M.,Zheng T.S.,Davis R.J.,Rakic P.,Flavell R.A.
Absence of excitotoxicity-induced apoptosis in the hippocampus of mice lacking the Jnk3 gene.
Nature
389
865-870
1997
443224
Koyano S.,Ito M.,Takamatsu N.,Shiba T.,Yamamoto K.,Yoshioka K.
A novel Jun N-terminal kinase (JNK)-binding protein that enhances the activation of JNK by MEK kinase 1 and TGF-beta-activated kinase 1.
FEBS Lett.
457
385-388
1999
443225
Morrison B.E.,Majdzadeh N.,Zhang X.,Lyles A.,Bassel-Duby R.,Olson E.N.,D'Mello S.R.
Neuroprotection by histone deacetylase-related protein.
Mol. Cell. Biol.
26
3550-3564
2006
443226
Kim Y.,Zhou P.,Qian L.,Chuang J.Z.,Lee J.,Li C.,Iadecola C.,Nathan C.,Ding A.
MyD88-5 links mitochondria, microtubules, and JNK3 in neurons and regulates neuronal survival.
J. Exp. Med.
204
2063-2074
2007
443227
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
443228
Choi W.S.,Abel G.,Klintworth H.,Flavell R.A.,Xia Z.
JNK3 mediates paraquat- and rotenone-induced dopaminergic neuron death.
J. Neuropathol. Exp. Neurol.
69
511-520
2010
443229
Atkinson P.J.,Cho C.H.,Hansen M.R.,Green S.H.
Activity of all JNK isoforms contributes to neurite growth in spiral ganglion neurons.
Hear. Res.
278
77-85
2011
443230
Yoshitane H.,Honma S.,Imamura K.,Nakajima H.,Nishide S.Y.,Ono D.,Kiyota H.,Shinozaki N.,Matsuki H.,Wada N.,Doi H.,Hamada T.,Honma K.,Fukada Y.
JNK regulates the photic response of the mammalian circadian clock.
EMBO Rep.
13
455-461
2012