Sequence of MK10_HUMAN
EC Number:2.7.11.24
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
ATP + a [protein]-(L-serine/L-threonine) = ADP + a [protein]-(L-serine/L-threonine) phosphate
Other sequences found for EC No. 2.7.11.24
General information:
Sequence
0 MSLHFLYYCS EPTLDVKIAF CQGFDKQVDV SYIAKHYNMS KSKVDNQFYS VEVGDSTFTV
60 LKRYQNLKPI GSGAQGIVCA AYDAVLDRNV AIKKLSRPFQ NQTHAKRAYR ELVLMKCVNH
120 KNIISLLNVF TPQKTLEEFQ DVYLVMELMD ANLCQVIQME LDHERMSYLL YQMLCGIKHL
180 HSAGIIHRDL KPSNIVVKSD CTLKILDFGL ARTAGTSFMM TPYVVTRYYR APEVILGMGY
240 KENVDIWSVG CIMGEMVRHK ILFPGRDYID QWNKVIEQLG TPCPEFMKKL QPTVRNYVEN
300 RPKYAGLTFP KLFPDSLFPA DSEHNKLKAS QARDLLSKML VIDPAKRISV DDALQHPYIN
360 VWYDPAEVEA PPPQIYDKQL DEREHTIEEW KELIYKEVMN SEEKTKNGVV KGQPSPSGAA
420 VNSSESLPPS SSVNDISSMS TDQTLASDTD SSLEASAGPL GCCR
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
443202
Mohit A.A.,Martin J.H.,Miller C.A.
p493F12 kinase: a novel MAP kinase expressed in a subset of neurons in the human nervous system.
Neuron
14
67-78
1995
443203
Gupta S.,Barrett T.,Whitmarsh A.J.,Cavanagh J.,Sluss H.K.,Derijard B.,Davis R.J.
Selective interaction of JNK protein kinase isoforms with transcription factors.
EMBO J.
15
2760-2770
1996
443204
Ota T.,Suzuki Y.,Nishikawa T.,Otsuki T.,Sugiyama T.,Irie R.,Wakamatsu A.,Hayashi K.,Sato H.,Nagai K.,Kimura K.,Makita H.,Sekine M.,Obayashi M.,Nishi T.,Shibahara T.,Tanaka T.,Ishii S.,Yamamoto J.,Saito K.,Kawai Y.,Isono Y.,Nakamura Y.,Nagahari K.,Murakami K.,Yasuda T.,Iwayanagi T.,Wagatsuma M.,Shiratori A.,Sudo H.,Hosoiri T.,Kaku Y.,Kodaira H.,Kondo H.,Sugawara M.,Takahashi M.,Kanda K.,Yokoi T.,Furuya T.,Kikkawa E.,Omura Y.,Abe K.,Kamihara K.,Katsuta N.,Sato K.,Tanikawa M.,Yamazaki M.,Ninomiya K.,Ishibashi T.,Yamashita H.,Murakawa K.,Fujimori K.,Tanai H.,Kimata M.,Watanabe M.,Hiraoka S.,Chiba Y.,Ishida S.,Ono Y.,Takiguchi S.,Watanabe S.,Yosida M.,Hotuta T.,Kusano J.,Kanehori K.,Takahashi-Fujii A.,Hara H.,Tanase T.-O.,Nomura Y.,Togiya S.,Komai F.,Hara R.,Takeuchi K.,Arita M.,Imose N.,Musashino K.,Yuuki H.,Oshima A.,Sasaki N.,Aotsuka S.,Yoshikawa Y.,Matsunawa H.,Ichihara T.,Shiohata N.,Sano S.,Moriya S.,Momiyama H.,Satoh N.,Takami S.,Terashima Y.,Suzuki O.,Nakagawa S.,Senoh A.,Mizoguchi H.,Goto Y.,Shimizu F.,Wakebe H.,Hishigaki H.,Watanabe T.,Sugiyama A.,Takemoto M.,Kawakami B.,Yamazaki M.,Watanabe K.,Kumagai A.,Itakura S.,Fukuzumi Y.,Fujimori Y.,Komiyama M.,Tashiro H.,Tanigami A.,Fujiwara T.,Ono T.,Yamada K.,Fujii Y.,Ozaki K.,Hirao M.,Ohmori Y.,Kawabata A.,Hikiji T.,Kobatake N.,Inagaki H.,Ikema Y.,Okamoto S.,Okitani R.,Kawakami T.,Noguchi S.,Itoh T.,Shigeta K.,Senba T.,Matsumura K.,Nakajima Y.,Mizuno T.,Morinaga M.,Sasaki M.,Togashi T.,Oyama M.,Hata H.,Watanabe M.,Komatsu T.,Mizushima-Sugano J.,Satoh T.,Shirai Y.,Takahashi Y.,Nakagawa K.,Okumura K.,Nagase T.,Nomura N.,Kikuchi H.,Masuho Y.,Yamashita R.,Nakai K.,Yada T.,Nakamura Y.,Ohara O.,Isogai T.,Sugano S.
Complete sequencing and characterization of 21,243 full-length human cDNAs.
Nat. Genet.
36
40-45
2004
443205
Hillier L.W.,Graves T.A.,Fulton R.S.,Fulton L.A.,Pepin K.H.,Minx P.,Wagner-McPherson C.,Layman D.,Wylie K.,Sekhon M.,Becker M.C.,Fewell G.A.,Delehaunty K.D.,Miner T.L.,Nash W.E.,Kremitzki C.,Oddy L.,Du H.,Sun H.,Bradshaw-Cordum H.,Ali J.,Carter J.,Cordes M.,Harris A.,Isak A.,van Brunt A.,Nguyen C.,Du F.,Courtney L.,Kalicki J.,Ozersky P.,Abbott S.,Armstrong J.,Belter E.A.,Caruso L.,Cedroni M.,Cotton M.,Davidson T.,Desai A.,Elliott G.,Erb T.,Fronick C.,Gaige T.,Haakenson W.,Haglund K.,Holmes A.,Harkins R.,Kim K.,Kruchowski S.S.,Strong C.M.,Grewal N.,Goyea E.,Hou S.,Levy A.,Martinka S.,Mead K.,McLellan M.D.,Meyer R.,Randall-Maher J.,Tomlinson C.,Dauphin-Kohlberg S.,Kozlowicz-Reilly A.,Shah N.,Swearengen-Shahid S.,Snider J.,Strong J.T.,Thompson J.,Yoakum M.,Leonard S.,Pearman C.,Trani L.,Radionenko M.,Waligorski J.E.,Wang C.,Rock S.M.,Tin-Wollam A.-M.,Maupin R.,Latreille P.,Wendl M.C.,Yang S.-P.,Pohl C.,Wallis J.W.,Spieth J.,Bieri T.A.,Berkowicz N.,Nelson J.O.,Osborne J.,Ding L.,Meyer R.,Sabo A.,Shotland Y.,Sinha P.,Wohldmann P.E.,Cook L.L.,Hickenbotham M.T.,Eldred J.,Williams D.,Jones T.A.,She X.,Ciccarelli F.D.,Izaurralde E.,Taylor J.,Schmutz J.,Myers R.M.,Cox D.R.,Huang X.,McPherson J.D.,Mardis E.R.,Clifton S.W.,Warren W.C.,Chinwalla A.T.,Eddy S.R.,Marra M.A.,Ovcharenko I.,Furey T.S.,Miller W.,Eichler E.E.,Bork P.,Suyama M.,Torrents D.,Waterston R.H.,Wilson R.K.
Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
Nature
434
724-731
2005
443207
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
443208
Lisnock J.,Griffin P.,Calaycay J.,Frantz B.,Parsons J.,O'Keefe S.J.,LoGrasso P.
Activation of JNK3 alpha 1 requires both MKK4 and MKK7: kinetic characterization of in vitro phosphorylated JNK3 alpha 1.
Biochemistry
39
3141-3148
2000
443209
Fleming Y.,Armstrong C.G.,Morrice N.,Paterson A.,Goedert M.,Cohen P.
Synergistic activation of stress-activated protein kinase 1/c-Jun N-terminal kinase (SAPK1/JNK) isoforms by mitogen-activated protein kinase kinase 4 (MKK4) and MKK7.
Biochem. J.
352
145-154
2000
443210
Neidhart S.,Antonsson B.,Gillieron C.,Vilbois F.,Grenningloh G.,Arkinstall S.
c-Jun N-terminal kinase-3 (JNK3)/stress-activated protein kinase-beta (SAPKbeta) binds and phosphorylates the neuronal microtubule regulator SCG10.
FEBS Lett.
508
259-264
2001
443211
Jagadish N.,Rana R.,Selvi R.,Mishra D.,Garg M.,Yadav S.,Herr J.C.,Okumura K.,Hasegawa A.,Koyama K.,Suri A.
Characterization of a novel human sperm-associated antigen 9 (SPAG9) having structural homology with c-Jun N-terminal kinase-interacting protein.
Biochem. J.
389
73-82
2005
443212
Shoichet S.A.,Duprez L.,Hagens O.,Waetzig V.,Menzel C.,Herdegen T.,Schweiger S.,Dan B.,Vamos E.,Ropers H.-H.,Kalscheuer V.M.
Truncation of the CNS-expressed JNK3 in a patient with a severe developmental epileptic encephalopathy.
Hum. Genet.
118
559-567
2006
443213
Song X.,Raman D.,Gurevich E.V.,Vishnivetskiy S.A.,Gurevich V.V.
Visual and both non-visual arrestins in their 'inactive' conformation bind JNK3 and Mdm2 and relocalize them from the nucleus to the cytoplasm.
J. Biol. Chem.
281
21491-21499
2006
443214
Morrison B.E.,Majdzadeh N.,Zhang X.,Lyles A.,Bassel-Duby R.,Olson E.N.,D'Mello S.R.
Neuroprotection by histone deacetylase-related protein.
Mol. Cell. Biol.
26
3550-3564
2006
443215
Xu T.-R.,Baillie G.S.,Bhari N.,Houslay T.M.,Pitt A.M.,Adams D.R.,Kolch W.,Houslay M.D.,Milligan G.
Mutations of beta-arrestin 2 that limit self-association also interfere with interactions with the beta2-adrenoceptor and the ERK1/2 MAPKs: implications for beta2-adrenoceptor signalling via the ERK1/2 MAPKs.
Biochem. J.
413
51-60
2008
443216
Yang G.,Liu Y.,Yang K.,Liu R.,Zhu S.,Coquinco A.,Wen W.,Kojic L.,Jia W.,Cynader M.
Isoform-specific palmitoylation of JNK regulates axonal development.
Cell Death Differ.
19
553-561
2012
443217
Yoshitane H.,Honma S.,Imamura K.,Nakajima H.,Nishide S.Y.,Ono D.,Kiyota H.,Shinozaki N.,Matsuki H.,Wada N.,Doi H.,Hamada T.,Honma K.,Fukada Y.
JNK regulates the photic response of the mammalian circadian clock.
EMBO Rep.
13
455-461
2012
443218
Huang J.,Gurung B.,Wan B.,Matkar S.,Veniaminova N.A.,Wan K.,Merchant J.L.,Hua X.,Lei M.
The same pocket in menin binds both MLL and JUND but has opposite effects on transcription.
Nature
482
542-546
2012
443219
Xie X.,Gu Y.,Fox T.,Coll J.T.,Fleming M.A.,Markland W.,Caron P.R.,Wilson K.P.,Su M.S.-S.
Crystal structure of JNK3: a kinase implicated in neuronal apoptosis.
Structure
6
983-991
1998
