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Sequence of KMO_YEAST

EC Number:1.14.13.9

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
kynurenine 3-monooxygenase
P38169
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
460
52429
Reaction
L-kynurenine + NADPH + H+ + O2 = 3-hydroxy-L-kynurenine + NADP+ + H2O
Other sequences found for EC No. 1.14.13.9

General information:

Sequence
show sequence in fasta format
  0 MSESVAIIGA GLVGCLAALA FSKEGYNVTL YDFRQDPRLD TTKNKNLKSI NLAISARGID
 60 ALKSIDPDAC EHILQDMIPM KGRMIHDLKG RQESQLYGLH GEAINSINRS VLNNSLLDEL
120 EKSTTELKFG HKLVKIEWTD DKQICHFAIG EDLKTPHTEK YDFVIGCDGA YSATRSQMQR
180 KVEMDFSQEY MNLRYIELYI PPTEEFKPNY GGNFAIAPDH LHIWPRHKFM LIALANSDGS
240 FTSTFFGSKD QISDLITSKS RVREFLIENF PDIINIMDLD DAVKRFITYP KESLVCVNCK
300 PYDVPGGKAI LLGDAAHAMV PFYGQGMNCG FEDVRILMAL LKKHSGDRSR AFTEYTQTRH
360 KDLVSITELA KRNYKEMSHD VTSKRFLLRK KLDALFSIIM KDKWIPLYTM ISFRSDISYS
420 RALERAGKQT RILKFLESLT LGMLSIGGYK LFKFLTRERS
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
435390
Obermaier B.,Gassenhuber J.,Piravandi E.,Domdey H.
Sequence analysis of a 78.6 kb segment of the left end of Saccharomyces cerevisiae chromosome II.
Yeast
11
1103-1112
1995
435391
Feldmann H.,Aigle M.,Aljinovic G.,Andre B.,Baclet M.C.,Barthe C.,Baur A.,Becam A.-M.,Biteau N.,Boles E.,Brandt T.,Brendel M.,Brueckner M.,Bussereau F.,Christiansen C.,Contreras R.,Crouzet M.,Cziepluch C.,Demolis N.,Delaveau T.,Doignon F.,Domdey H.,Duesterhus S.,Dubois E.,Dujon B.,El Bakkoury M.,Entian K.-D.,Feuermann M.,Fiers W.,Fobo G.M.,Fritz C.,Gassenhuber J.,Glansdorff N.,Goffeau A.,Grivell L.A.,de Haan M.,Hein C.,Herbert C.J.,Hollenberg C.P.,Holmstroem K.,Jacq C.,Jacquet M.,Jauniaux J.-C.,Jonniaux J.-L.,Kallesoee T.,Kiesau P.,Kirchrath L.,Koetter P.,Korol S.,Liebl S.,Logghe M.,Lohan A.J.E.,Louis E.J.,Li Z.Y.,Maat M.J.,Mallet L.,Mannhaupt G.,Messenguy F.,Miosga T.,Molemans F.,Mueller S.,Nasr F.,Obermaier B.,Perea J.,Pierard A.,Piravandi E.,Pohl F.M.,Pohl T.M.,Potier S.,Proft M.,Purnelle B.,Ramezani Rad M.,Rieger M.,Rose M.,Schaaff-Gerstenschlaeger I.,Scherens B.,Schwarzlose C.,Skala J.,Slonimski P.P.,Smits P.H.M.,Souciet J.-L.,Steensma H.Y.,Stucka R.,Urrestarazu L.A.,van der Aart Q.J.M.,Van Dyck L.,Vassarotti A.,Vetter I.,Vierendeels F.,Vissers S.,Wagner G.,de Wergifosse P.,Wolfe K.H.,Zagulski M.,Zimmermann F.K.,Mewes H.-W.,Kleine K.
Complete DNA sequence of yeast chromosome II.
EMBO J.
13
5795-5809
1994
435392
Engel S.R.,Dietrich F.S.,Fisk D.G.,Binkley G.,Balakrishnan R.,Costanzo M.C.,Dwight S.S.,Hitz B.C.,Karra K.,Nash R.S.,Weng S.,Wong E.D.,Lloyd P.,Skrzypek M.S.,Miyasato S.R.,Simison M.,Cherry J.M.
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
G3 (Bethesda)
4
389-398
2014
435393
Hu Y.,Rolfs A.,Bhullar B.,Murthy T.V.S.,Zhu C.,Berger M.F.,Camargo A.A.,Kelley F.,McCarron S.,Jepson D.,Richardson A.,Raphael J.,Moreira D.,Taycher E.,Zuo D.,Mohr S.,Kane M.F.,Williamson J.,Simpson A.J.G.,Bulyk M.L.,Harlow E.,Marsischky G.,Kolodner R.D.,LaBaer J.
Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
Genome Res.
17
536-543
2007
435394
Panozzo C.,Nawara M.,Suski C.,Kucharczyka R.,Skoneczny M.,Becam A.-M.,Rytka J.,Herbert C.J.
Aerobic and anaerobic NAD+ metabolism in Saccharomyces cerevisiae.
FEBS Lett.
517
97-102
2002
435395
Zahedi R.P.,Sickmann A.,Boehm A.M.,Winkler C.,Zufall N.,Schoenfisch B.,Guiard B.,Pfanner N.,Meisinger C.
Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.
Mol. Biol. Cell
17
1436-1450
2006
435396
Sickmann A.,Reinders J.,Wagner Y.,Joppich C.,Zahedi R.P.,Meyer H.E.,Schoenfisch B.,Perschil I.,Chacinska A.,Guiard B.,Rehling P.,Pfanner N.,Meisinger C.
The proteome of Saccharomyces cerevisiae mitochondria.
Proc. Natl. Acad. Sci. U.S.A.
100
13207-13212
2003
435397
Huh W.-K.,Falvo J.V.,Gerke L.C.,Carroll A.S.,Howson R.W.,Weissman J.S.,O'Shea E.K.
Global analysis of protein localization in budding yeast.
Nature
425
686-691
2003
435398
Ghaemmaghami S.,Huh W.-K.,Bower K.,Howson R.W.,Belle A.,Dephoure N.,O'Shea E.K.,Weissman J.S.
Global analysis of protein expression in yeast.
Nature
425
737-741
2003
435399
Giorgini F.,Guidetti P.,Nguyen Q.,Bennett S.C.,Muchowski P.J.
A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington disease.
Nat. Genet.
37
526-531
2005
435400
Amaral M.,Levy C.,Heyes D.J.,Lafite P.,Outeiro T.F.,Giorgini F.,Leys D.,Scrutton N.S.
Structural basis of kynurenine 3-monooxygenase inhibition.
Nature
496
382-385
2013
435401
Kim H.T.,Na B.K.,Chung J.,Kim S.,Kwon S.K.,Cha H.,Son J.,Cho J.M.,Hwang K.Y.
Structural Basis for Inhibitor-Induced Hydrogen Peroxide Production by Kynurenine 3-Monooxygenase.
Cell Chem. Biol.
0
0-0
2018