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Sequence of GLN1A_BACSU

EC Number:6.3.1.2

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
glutamine synthetase
P12425
Bacillus subtilis (strain 168)
444
50278
Reaction
ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine
Other sequences found for EC No. 6.3.1.2

General information:

Sequence
show sequence in fasta format
  0 MAKYTREDIE KLVKEENVKY IRLQFTDILG TIKNVEIPVS QLGKALDNKV MFDGSSIEGF
 60 VRIEESDMYL YPDLNTFVIF PWTAEKGKVA RFICDIYNPD GTPFEGDPRN NLKRILKEME
120 DLGFSDFNLG PEPEFFLFKL DEKGEPTLEL NDKGGYFDLA PTDLGENCRR DIVLELEEMG
180 FEIEASHHEV APGQHEIDFK YAGAVRSCDD IQTFKLVVKT IARKHGLHAT FMPKPLFGVN
240 GSGMHCNLSL FKNGVNAFFD ENADLQLSET AKHFIAGIVK HATSFTAVTN PTVNSYKRLV
300 PGYEAPCYVA WSAQNRSPLI RIPASRGIST RVEVRSVDPA ANPYLALSVL LAAGLDGIKN
360 KLEAPAPIDR NIYVMSKEER MENGIVDLPA TLAEALEEFK SNEVMVKALG EHLFEHFIEA
420 KEIEWDMFRT QVHPWEREQY MSQY
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
38549
Strauch M.A.,Aronson A.I.,Brown S.W.,Schreier H.J.,Sonenshein A.L.
Sequence of the Bacillus subtilis glutamine synthetase gene region.
Gene
71
257-265
1988
38550
Nakano Y.,Tanaka E.,Kato C.,Kimura K.,Horikoshi K.
The complete nucleotide sequence of the glutamine synthetase gene (glnA) of Bacillus subtilis.
FEMS Microbiol. Lett.
48
81-86
1989
38552
Kunst F.,Ogasawara N.,Moszer I.,Albertini A.M.,Alloni G.,Azevedo V.,Bertero M.G.,Bessieres P.,Bolotin A.,Borchert S.,Borriss R.,Boursier L.,Brans A.,Braun M.,Brignell S.C.,Bron S.,Brouillet S.,Bruschi C.V.,Caldwell B.,Capuano V.,Carter N.M.,Choi S.-K.,Codani J.-J.,Connerton I.F.,Cummings N.J.,Daniel R.A.,Denizot F.,Devine K.M.,Duesterhoeft A.,Ehrlich S.D.,Emmerson P.T.,Entian K.-D.,Errington J.,Fabret C.,Ferrari E.,Foulger D.,Fritz C.,Fujita M.,Fujita Y.,Fuma S.,Galizzi A.,Galleron N.,Ghim S.-Y.,Glaser P.,Goffeau A.,Golightly E.J.,Grandi G.,Guiseppi G.,Guy B.J.,Haga K.,Haiech J.,Harwood C.R.,Henaut A.,Hilbert H.,Holsappel S.,Hosono S.,Hullo M.-F.,Itaya M.,Jones L.-M.,Joris B.,Karamata D.,Kasahara Y.,Klaerr-Blanchard M.,Klein C.,Kobayashi Y.,Koetter P.,Koningstein G.,Krogh S.,Kumano M.,Kurita K.,Lapidus A.,Lardinois S.,Lauber J.,Lazarevic V.,Lee S.-M.,Levine A.,Liu H.,Masuda S.,Mauel C.,Medigue C.,Medina N.,Mellado R.P.,Mizuno M.,Moestl D.,Nakai S.,Noback M.,Noone D.,O'Reilly M.,Ogawa K.,Ogiwara A.,Oudega B.,Park S.-H.,Parro V.,Pohl T.M.,Portetelle D.,Porwollik S.,Prescott A.M.,Presecan E.,Pujic P.,Purnelle B.,Rapoport G.,Rey M.,Reynolds S.,Rieger M.,Rivolta C.,Rocha E.,Roche B.,Rose M.,Sadaie Y.,Sato T.,Scanlan E.,Schleich S.,Schroeter R.,Scoffone F.,Sekiguchi J.,Sekowska A.,Seror S.J.,Serror P.,Shin B.-S.,Soldo B.,Sorokin A.,Tacconi E.,Takagi T.,Takahashi H.,Takemaru K.,Takeuchi M.,Tamakoshi A.,Tanaka T.,Terpstra P.,Tognoni A.,Tosato V.,Uchiyama S.,Vandenbol M.,Vannier F.,Vassarotti A.,Viari A.,Wambutt R.,Wedler E.,Wedler H.,Weitzenegger T.,Winters P.,Wipat A.,Yamamoto H.,Yamane K.,Yasumoto K.,Yata K.,Yoshida K.,Yoshikawa H.-F.,Zumstein E.,Yoshikawa H.,Danchin A.
The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.
Nature
390
249-256
1997
38553
Deuel T.F.,Prusiner S.
Regulation of glutamine synthetase from Bacillus subtilis by divalent cations, feedback inhibitors, and L-glutamine.
J. Biol. Chem.
249
257-264
1974
38554
Schreier H.J.,Brown S.W.,Hirschi K.D.,Nomellini J.F.,Sonenshein A.L.
Regulation of Bacillus subtilis glutamine synthetase gene expression by the product of the glnR gene.
J. Mol. Biol.
210
51-63
1989
38555
Schreier H.J.,Rostkowski C.A.,Kellner E.M.
Altered regulation of the glnRA operon in a Bacillus subtilis mutant that produces methionine sulfoximine-tolerant glutamine synthetase.
J. Bacteriol.
175
892-897
1993
38556
Wray L.V. Jr.,Ferson A.E.,Rohrer K.,Fisher S.H.
TnrA, a transcription factor required for global nitrogen regulation in Bacillus subtilis.
Proc. Natl. Acad. Sci. U.S.A.
93
8841-8845
1996
38557
Wray L.V. Jr.,Zalieckas J.M.,Fisher S.H.
Bacillus subtilis glutamine synthetase controls gene expression through a protein-protein interaction with transcription factor TnrA.
Cell
107
427-435
2001
38558
Fisher S.H.,Brandenburg J.L.,Wray L.V. Jr.
Mutations in Bacillus subtilis glutamine synthetase that block its interaction with transcription factor TnrA.
Mol. Microbiol.
45
627-635
2002
38559
Heinrich A.,Woyda K.,Brauburger K.,Meiss G.,Detsch C.,Stuelke J.,Forchhammer K.
Interaction of the membrane-bound GlnK-AmtB complex with the master regulator of nitrogen metabolism TnrA in Bacillus subtilis.
J. Biol. Chem.
281
34909-34917
2006
38560
Murray D.S.,Chinnam N.,Tonthat N.K.,Whitfill T.,Wray L.V. Jr.,Fisher S.H.,Schumacher M.A.
Structures of the Bacillus subtilis glutamine synthetase dodecamer reveal large intersubunit catalytic conformational changes linked to a unique feedback inhibition mechanism.
J. Biol. Chem.
288
35801-35811
2013
38561
Schumacher M.A.,Chinnam N.B.,Cuthbert B.,Tonthat N.K.,Whitfill T.
Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis.
Genes Dev.
29
451-464
2015