Sequence of DRTS_PLAVI
EC Number:2.1.1.45
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP
Other sequences found for EC No. 2.1.1.45
General information:
Sequence
0 MEDLSDVFDI YAICACCKVA PTSEGTKNEP FSPRTFRGLG NKGTLPWKCN SVDMKYFSSV
60 TTYVDESKYE KLKWKRERYL RMEASQGGGD NTSGGDNTHG GDNADKLQNV VVMGRSSWES
120 IPKQYKPLPN RINVVLSKTL TKEDVKEKVF IIDSIDDLLL LLKKLKYYKC FIIGGAQVYR
180 ECLSRNLIKQ IYFTRINGAY PCDVFFPEFD ESQFRVTSVS EVYNSKGTTL DFLVYSKVGG
240 GVDGGASNGS TATALRRTAM RSTAMRRNVA PRTAAPPMGP HSRANGERAP PRARARRTTP
300 RQRKTTSCTS ALTTKWGRKT RSTCKILKFT TASRLMQHPE YQYLGIIYDI IMNGNKQGDR
360 TGVGVMSNFG YMMKFNLSEY FPLLTTKKLF LRGIIEELLW FIRGETNGNT LLNKNVRIWE
420 ANGTREFLDN RKLFHREVND LGPIYGFQWR HFGAEYTNMH DNYEDKGVDQ LKNVIHLIKN
480 EPTSRRIILC AWNVKDLDQM ALPPCHILCQ FYVFDGKLSC IMYQRSCDLG LGVPFNIASY
540 SIFTHMIAQV CNLQPAQFIH ILGNAHVYNN HVDSLKVQLN RIPYPFPTLK LNPEVKNIED
600 FTISDFTIEN YVHHDKITME MAA
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Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
411500
Eldin de Pecoulas P.,Basco L.K.,Tahar R.,Ouatas T.,Mazabraud A.
Analysis of the Plasmodium vivax dihydrofolate reductase-thymidylate synthase gene sequence.
Gene
211
177-185
1998
411501
Kongsaeree P.,Khongsuk P.,Leartsakulpanich U.,Chitnumsub P.,Tarnchompoo B.,Walkinshaw M.D.,Yuthavong Y.
Crystal structure of dihydrofolate reductase from Plasmodium vivax: pyrimethamine displacement linked with mutation-induced resistance.
Proc. Natl. Acad. Sci. U.S.A.
102
13046-13051
2005
