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Sequence of CDK16_MOUSE

EC Number:2.7.11.22

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
cyclin-dependent kinase
Q04735
Mus musculus
496
55914
Reaction
ATP + a [protein]-(L-serine/L-threonine) = ADP + a [protein]-(L-serine/L-threonine) phosphate
Other sequences found for EC No. 2.7.11.22

General information:

Sequence
show sequence in fasta format
  0 MDRMKKIKRQ LSMTLRGGRG IDKTNGVPEQ IGLDESGGGG GSDLGEAPTR IAPGELRSVR
 60 GPLSSAPEIV HEDMKMGSDG ESDQASATSS DEVQSPVRVR MRNHPPRKIS TEDINKRLSL
120 PADIRLPEGY LEKLTLNSPI FDKPLSRRLR RVSLSEIGFG KLETYIKLDK LGEGTYATVY
180 KGKSKLTDNL VALKEIRLEH EEGAPCTAIR EVSLLKDLKH ANIVTLHDII HTEKSLTLVF
240 EYLDKDLKQY LDDCGNVINM HNVKLFLFQL LRGLAYCHRQ KVLHRDLKPQ NLLINERGEL
300 KLADFGLARA KSIPTKTYSN EVVTLWYRPP DILLGSTDYS TQIDMWGVGC IFYEMATGRP
360 LFPGSTVEEQ LHFIFRILGT PTEETWPGIL SNEEFRTYNY PKYRAEALLS HAPRLDSDGA
420 DLLTKLLQFE GRNRISAEDA RKHPFFLSLG ERIHKLPDTT SIFALKEVQL QKEANIRSTS
480 MPDSGRPAFR VVDTEF
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
399860
Okuda T.,Cleveland J.L.,Downing J.R.
PCTAIRE-1 and PCTAIRE-3, two members of a novel cdc2/CDC28-related protein kinase gene family.
Oncogene
7
2249-2258
1992
399861
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Genome Res.
14
2121-2127
2004
399862
Ershler M.A.,Nagorskaya T.V.,Visser J.W.M.,Belyavsky A.V.
Novel CDC2-related protein kinases produced in murine hematopoietic stem cells.
Gene
124
305-306
1993
399863
Sladeczek F.,Camonis J.H.,Burnol A.-F.,Le Bouffant F.
The Cdk-like protein PCTAIRE-1 from mouse brain associates with p11 and 14-3-3 proteins.
Mol. Gen. Genet.
254
571-577
1997
399864
Liu Y.,Cheng K.,Gong K.,Fu A.K.,Ip N.Y.
Pctaire1 phosphorylates N-ethylmaleimide-sensitive fusion protein: implications in the regulation of its hexamerization and exocytosis.
J. Biol. Chem.
281
9852-9858
2006
399865
Huttlin E.L.,Jedrychowski M.P.,Elias J.E.,Goswami T.,Rad R.,Beausoleil S.A.,Villen J.,Haas W.,Sowa M.E.,Gygi S.P.
A tissue-specific atlas of mouse protein phosphorylation and expression.
Cell
143
1174-1189
2010
399866
Fu W.Y.,Cheng K.,Fu A.K.,Ip N.Y.
Cyclin-dependent kinase 5-dependent phosphorylation of Pctaire1 regulates dendrite development.
Neuroscience
180
353-359
2011
399867
Shehata S.N.,Hunter R.W.,Ohta E.,Peggie M.W.,Lou H.J.,Sicheri F.,Zeqiraj E.,Turk B.E.,Sakamoto K.
Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase.
Cell. Signal.
24
2085-2094
2012
399868
Chen X.Y.,Gu X.T.,Saiyin H.,Wan B.,Zhang Y.J.,Li J.,Wang Y.L.,Gao R.,Wang Y.F.,Dong W.P.,Najjar S.M.,Zhang C.Y.,Ding H.F.,Liu J.O.,Yu L.
Brain-selective kinase 2 (BRSK2) phosphorylation on PCTAIRE1 negatively regulates glucose-stimulated insulin secretion in pancreatic beta-cells.
J. Biol. Chem.
287
30368-30375
2012
399869
Mikolcevic P.,Sigl R.,Rauch V.,Hess M.W.,Pfaller K.,Barisic M.,Pelliniemi L.J.,Boesl M.,Geley S.
Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis.
Mol. Cell. Biol.
32
868-879
2012