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Sequence of FUM1_LEIMA

EC Number:4.2.1.2

EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
fumarate hydratase
Q4QAU9
Leishmania major
549
60808
Reaction
(S)-malate = fumarate + H2O
Other sequences found for EC No. 4.2.1.2

General information:

Sequence
show sequence in fasta format
  0 MLRRLAPLLA EFNFVPLVSK VSHKETKYRL LTKDYVSVVQ PGAGLPEMLR VDPAALTLLS
 60 STAFDDVEHL LRSSHLMSLR KIFDDPEASD NDKFVALQLL KNANISSARL LPGCQDTGTA
120 IIAGYRGDQV FVPGNDEEAL SRGVYDIFQK RNFRYSQNVP LSMYDEKNTG TNLPAQIDLY
180 ASKGMEYSFM FVAKGGGSAN KSFLLQETKS VLNPKSLRNF LKEKLAMFGT SACPPYHVAV
240 VIGGTSAEMT MKVLKYASCH YYDDLITKPD MKTGYTFRDL ELEEEVLKVC QNIGMGAQFG
300 GKYYAHDVRV IRMPRHGASC PIGIGVSCSA DRQALGKINK DGVWLEELEM EPSQYLPDLK
360 EDELLKTPAV MVNLNRPMPE VLQELSKHPV RTRLSLTGTI IVARDSAHAR MREMLEAGKP
420 LPQYMKEHPV YYAGPAKQPD GLPSGSFGPT TAGRMDPFVD LFQSHGGSMV MLAKGNRSKQ
480 VTKACHKYGG FYLGSIGGPA AVLAQNAIKK VECLDMKDLG MEAVWRIEVE NFPAFIVVDD
540 KGNDFFEQL
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Sequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
35678
Ivens A.C.,Peacock C.S.,Worthey E.A.,Murphy L.,Aggarwal G.,Berriman M.,Sisk E.,Rajandream M.A.,Adlem E.,Aert R.,Anupama A.,Apostolou Z.,Attipoe P.,Bason N.,Bauser C.,Beck A.,Beverley S.M.,Bianchettin G.,Borzym K.,Bothe G.,Bruschi C.V.,Collins M.,Cadag E.,Ciarloni L.,Clayton C.,Coulson R.M.R.,Cronin A.,Cruz A.K.,Davies R.M.,De Gaudenzi J.,Dobson D.E.,Duesterhoeft A.,Fazelina G.,Fosker N.,Frasch A.C.,Fraser A.,Fuchs M.,Gabel C.,Goble A.,Goffeau A.,Harris D.,Hertz-Fowler C.,Hilbert H.,Horn D.,Huang Y.,Klages S.,Knights A.,Kube M.,Larke N.,Litvin L.,Lord A.,Louie T.,Marra M.,Masuy D.,Matthews K.,Michaeli S.,Mottram J.C.,Mueller-Auer S.,Munden H.,Nelson S.,Norbertczak H.,Oliver K.,O'neil S.,Pentony M.,Pohl T.M.,Price C.,Purnelle B.,Quail M.A.,Rabbinowitsch E.,Reinhardt R.,Rieger M.,Rinta J.,Robben J.,Robertson L.,Ruiz J.C.,Rutter S.,Saunders D.,Schaefer M.,Schein J.,Schwartz D.C.,Seeger K.,Seyler A.,Sharp S.,Shin H.,Sivam D.,Squares R.,Squares S.,Tosato V.,Vogt C.,Volckaert G.,Wambutt R.,Warren T.,Wedler H.,Woodward J.,Zhou S.,Zimmermann W.,Smith D.F.,Blackwell J.M.,Stuart K.D.,Barrell B.G.,Myler P.J.
The genome of the kinetoplastid parasite, Leishmania major.
Science
309
436-442
2005
35679
Feliciano P.R.,Gupta S.,Dyszy F.,Dias-Baruffi M.,Costa-Filho A.J.,Michels P.A.,Nonato M.C.
Fumarate hydratase isoforms of Leishmania major: subcellular localization, structural and kinetic properties.
Int. J. Biol. Macromol.
51
25-31
2012
35680
Feliciano P.R.,Drennan C.L.,Nonato M.C.
Crystal structures of fumarate hydratases from Leishmania major in a complex with inhibitor 2-thiomalate.
ACS Chem. Biol.
14
266-275
2019