Sequence of FTME_ASPFM
EC Number:1.14.19.71
EC Number
Recommended Name
Accession Code
Organism
No of amino acids
Molecular Weight [Da]
Source
Reaction
tryprostatin A + [reduced NADPH-hemoprotein reductase] + O2 = fumitremorgin C + [oxidized NADPH-hemoprotein reductase] + 2 H2O
Other sequences found for EC No. 1.14.19.71
General information:
Sequence
0 MERLPLSPAV LFLIIVLPIL YLWIRYTAPA RPHGKHLSLP PGPPRLPKIG NLHQVPRQIP
60 WKKYKEWSDT YGPIMSVQLA DTIAVVFSSW DLIKNHIERR NTIYSSRPSV PFFLHATGGL
120 NASILPYGPE WKLQRAIRSS VLKPSMTVKY RDVQHVETTQ LLHELLSTND FPVCLRRCIA
180 SVFLTVAYGE RCVDHAGLEA IDRLEELNRA IALHAEALFS GAAGILTQLV LPKALVDRLP
240 VRWKKDADML HNRLTADLVA RTRAALVRPG WNWVKEFSMK DGIGSGDGDG EQGSKVELKR
300 LAYMVGSLYE ASMAASQALR VIILAGLLHP DATRRMHDEL DAVVGTGRLP DFHDAAQLPY
360 TQAFIKEAMR WRSLTPMGSP RATSDEDECR GYHIPCGATV LVNVWAINHD EAIFLDPFAF
420 QPERWIENPD LPQLMYGMGQ RACPGRHMGQ DSLFLATARL FWAFDMALPD GADPIDQERF
480 LDSGTTLAAF LPDFEVRFTP RSEKYQEVIE NSMAVLPDVL SISATP
Download this sequence
in fasta formatDownload all sequences for 1.14.19.71
in fasta format
in csv (Excel, OpenOffice) formatSequence related references
Sequence Reference
Authors
Title
Journal
Volume
Pages
Year
PubMed ID
35435
Kato N.,Suzuki H.,Takagi H.,Asami Y.,Kakeya H.,Uramoto M.,Usui T.,Takahashi S.,Sugimoto Y.,Osada H.
Identification of cytochrome P450s required for fumitremorgin biosynthesis in Aspergillus fumigatus.
ChemBioChem
10
920-928
2009
35436
Grundmann A.,Li S.M.
Overproduction, purification and characterization of FtmPT1, a brevianamide F prenyltransferase from Aspergillus fumigatus.
Microbiology
151
2199-2207
2005
35437
Maiya S.,Grundmann A.,Li S.M.,Turner G.
The fumitremorgin gene cluster of Aspergillus fumigatus: identification of a gene encoding brevianamide F synthetase.
ChemBioChem
7
1062-1069
2006
35438
Grundmann A.,Kuznetsova T.,Afiyatullov S.S.,Li S.M.
FtmPT2, an N-prenyltransferase from Aspergillus fumigatus, catalyses the last step in the biosynthesis of fumitremorgin B.
ChemBioChem
9
2059-2063
2008
35439
Steffan N.,Grundmann A.,Afiyatullov S.,Ruan H.,Li S.M.
FtmOx1, a non-heme Fe(II) and alpha-ketoglutarate-dependent dioxygenase, catalyses the endoperoxide formation of verruculogen in Aspergillus fumigatus.
Org. Biomol. Chem.
7
4082-4087
2009
35440
Jost M.,Zocher G.,Tarcz S.,Matuschek M.,Xie X.,Li S.M.,Stehle T.
Structure-function analysis of an enzymatic prenyl transfer reaction identifies a reaction chamber with modifiable specificity.
J. Am. Chem. Soc.
132
17849-17858
2010
35441
Wollinsky B.,Ludwig L.,Xie X.,Li S.M.
Breaking the regioselectivity of indole prenyltransferases: identification of regular C3-prenylated hexahydropyrrolo[2,3-b]indoles as side products of the regular C2-prenyltransferase FtmPT1.
Org. Biomol. Chem.
10
9262-9270
2012
35442
Kato N.,Suzuki H.,Okumura H.,Takahashi S.,Osada H.
A point mutation in ftmD blocks the fumitremorgin biosynthetic pathway in Aspergillus fumigatus strain Af293.
Biosci. Biotechnol. Biochem.
77
1061-1067
2013
